terfenadine has been researched along with Dermatitis, Atopic in 26 studies
Terfenadine: A selective histamine H1-receptor antagonist devoid of central nervous system depressant activity. The drug was used for ALLERGY but withdrawn due to causing LONG QT SYNDROME.
Dermatitis, Atopic: A chronic inflammatory genetically determined disease of the skin marked by increased ability to form reagin (IgE), with increased susceptibility to allergic rhinitis and asthma, and hereditary disposition to a lowered threshold for pruritus. It is manifested by lichenification, excoriation, and crusting, mainly on the flexural surfaces of the elbow and knee. In infants it is known as infantile eczema.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Fexofenadine (n = 201) significantly decreased the severity of pruritus compared with placebo (n = 199) (mean change in score -0." | 9.10 | Addition of fexofenadine to a topical corticosteroid reduces the pruritus associated with atopic dermatitis in a 1-week randomized, multicentre, double-blind, placebo-controlled, parallel-group study. ( Harada, S; Inagi, M; Kawashima, M; Nakagawa, H; Noguchi, T; Tango, T, 2003) |
| "We report the results of a double-blind, placebo-controlled, cross-over study of terfenadine 120 mg twice daily for pruritus in atopic dermatitis." | 9.06 | Failure of terfenadine in relieving the pruritus of atopic dermatitis. ( Berth-Jones, J; Graham-Brown, RA, 1989) |
| "The use of the nonsedating antihistamine terfenadine (60 mg twice daily) in the treatment of chronic idiopathic urticaria and contact urticaria associated with atopic dermatitis was assessed." | 9.06 | Terfenadine in the treatment of chronic idiopathic urticaria and atopic dermatitis. ( Hjorth, N, 1988) |
| "Fexofenadine (n = 201) significantly decreased the severity of pruritus compared with placebo (n = 199) (mean change in score -0." | 5.10 | Addition of fexofenadine to a topical corticosteroid reduces the pruritus associated with atopic dermatitis in a 1-week randomized, multicentre, double-blind, placebo-controlled, parallel-group study. ( Harada, S; Inagi, M; Kawashima, M; Nakagawa, H; Noguchi, T; Tango, T, 2003) |
| "We report the results of a double-blind, placebo-controlled, cross-over study of terfenadine 120 mg twice daily for pruritus in atopic dermatitis." | 5.06 | Failure of terfenadine in relieving the pruritus of atopic dermatitis. ( Berth-Jones, J; Graham-Brown, RA, 1989) |
| "The use of the nonsedating antihistamine terfenadine (60 mg twice daily) in the treatment of chronic idiopathic urticaria and contact urticaria associated with atopic dermatitis was assessed." | 5.06 | Terfenadine in the treatment of chronic idiopathic urticaria and atopic dermatitis. ( Hjorth, N, 1988) |
| " Marked sedation occurred in three of the first 10 subjects treated with topical doxepin, necessitating a reduction in dosage for the remaining six subjects." | 2.68 | The effects of topical doxepin on responses to histamine, substance P and prostaglandin E2 in human skin. ( Archer, CB; Kennedy, CT; Sabroe, RA, 1997) |
| " The itch responses provoked by wool fibres were significantly stronger in AD patients than in controls, whereas the histamine-induced dose-response curves for itch did not differ significantly between the two groups, who discriminated equally well between weak and strong histamine stimuli." | 2.67 | Itch and atopic dermatitis: clinical and experimental studies. ( Wahlgren, CF, 1991) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (19.23) | 18.7374 |
| 1990's | 7 (26.92) | 18.2507 |
| 2000's | 12 (46.15) | 29.6817 |
| 2010's | 1 (3.85) | 24.3611 |
| 2020's | 1 (3.85) | 2.80 |
| Authors | Studies |
|---|---|
| Ningombam, A | 1 |
| Handa, S | 1 |
| Srivastava, N | 1 |
| Mahajan, R | 1 |
| De, D | 1 |
| Izumi, N | 1 |
| Mizuguchi, H | 1 |
| Umehara, H | 1 |
| Ogino, S | 1 |
| Fukui, H | 1 |
| Andoh, T | 1 |
| Saito, A | 1 |
| Kuraishi, Y | 1 |
| Funakushi, N | 1 |
| Yamaguchi, T | 1 |
| Jiang, J | 1 |
| Imamura, S | 1 |
| Kuhara, T | 1 |
| Suto, H | 1 |
| Ueki, R | 1 |
| Kase, Y | 1 |
| Kobayashi, H | 1 |
| Ogawa, H | 1 |
| Ikeda, S | 1 |
| Kawashima, M | 1 |
| Tango, T | 1 |
| Noguchi, T | 1 |
| Inagi, M | 1 |
| Nakagawa, H | 1 |
| Harada, S | 1 |
| Urabe, K | 1 |
| Nakahara, T | 1 |
| Moroi, Y | 1 |
| Morita, K | 1 |
| Furue, M | 1 |
| Jackson, CM | 1 |
| Lee, DK | 1 |
| Lipworth, BJ | 1 |
| Takahashi, H | 1 |
| Ishida-Yamamoto, A | 1 |
| Iizuka, H | 1 |
| Izu, K | 1 |
| Tokura, Y | 1 |
| Yamashita, H | 1 |
| Makino, T | 1 |
| Mizukami, H | 1 |
| Nose, M | 1 |
| Maier, T | 1 |
| Herzinger, T | 1 |
| Holen, E | 1 |
| Elsayed, S | 1 |
| Nyfors, A | 1 |
| Goldsmith, P | 1 |
| Dowd, PM | 1 |
| García, G | 1 |
| DeMora, F | 1 |
| Ferrer, L | 1 |
| Puigdemont, A | 1 |
| Sabroe, RA | 1 |
| Kennedy, CT | 2 |
| Archer, CB | 1 |
| Phillips, RL | 1 |
| Koenig, CJ | 1 |
| Amon, U | 1 |
| Amon, S | 1 |
| Gibbs, BF | 1 |
| Purohit, A | 1 |
| Duvernelle, C | 1 |
| Melac, M | 1 |
| Pauli, G | 1 |
| Frossard, N | 1 |
| Wahlgren, CF | 2 |
| Massey, WA | 1 |
| Lichtenstein, LM | 1 |
| Hägermark, O | 1 |
| Bergström, R | 1 |
| Doherty, V | 1 |
| Sylvester, DG | 1 |
| Harvey, SG | 1 |
| Calthrop, JG | 1 |
| Gibson, JR | 1 |
| Berth-Jones, J | 1 |
| Graham-Brown, RA | 1 |
| Castro Torres, A | 1 |
| Martín Moreno, L | 1 |
| Jiménez Reyes, J | 1 |
| Riesgo Bucher, Y | 1 |
| Hjorth, N | 1 |
| Takahashi, GY | 1 |
2 reviews available for terfenadine and Dermatitis, Atopic
| Article | Year |
|---|---|
The new H1 antihistamines. Treatment of urticaria and other clinical problems.
Topics: Astemizole; Cetirizine; Dermatitis, Atopic; Histamine H1 Antagonists; Humans; Loratadine; Terfenadin | 1993 |
The effects of antihistamines beyond H1 antagonism in allergic inflammation.
Topics: Benzhydryl Compounds; Cetirizine; Cyproheptadine; Dermatitis, Atopic; Histamine H1 Antagonists; Hist | 1990 |
14 trials available for terfenadine and Dermatitis, Atopic
| Article | Year |
|---|---|
Addition of oral fexofenadine to topical therapy leads to a significantly greater reduction in the serum interleukin-31 levels in mild to moderate paediatric atopic dermatitis.
Topics: Administration, Topical; Child; Dermatitis, Atopic; Double-Blind Method; Humans; Interleukins; Prosp | 2022 |
Addition of fexofenadine to a topical corticosteroid reduces the pruritus associated with atopic dermatitis in a 1-week randomized, multicentre, double-blind, placebo-controlled, parallel-group study.
Topics: Adolescent; Adult; Aged; Anti-Allergic Agents; Dermatitis, Atopic; Dermatologic Agents; Double-Blind | 2003 |
Mite-antigen induced immediate reactions in atopic dermatitis are inhibited by daily administration of fexofenadine.
Topics: Administration, Oral; Adult; Animals; Antigens, Dermatophagoides; Dermatitis, Allergic Contact; Derm | 2003 |
The effects of butterbur on the histamine and allergen cutaneous response.
Topics: Acetates; Adult; Anti-Inflammatory Agents; Cross-Over Studies; Cyclopropanes; Dermatitis, Atopic; Do | 2004 |
Effects of bepotastine, cetirizine, fexofenadine, and olopatadine on histamine-induced wheal-and flare-response, sedation, and psychomotor performance.
Topics: Adult; Cetirizine; Cross-Over Studies; Dermatitis, Atopic; Dibenzoxepins; Double-Blind Method; Femal | 2004 |
The effects of topical doxepin on responses to histamine, substance P and prostaglandin E2 in human skin.
Topics: Administration, Topical; Adult; Antipruritics; Dermatitis, Atopic; Dinoprostone; Double-Blind Method | 1997 |
Twenty-four hours of activity of cetirizine and fexofenadine in the skin.
Topics: Adolescent; Adult; Anti-Allergic Agents; Cetirizine; Cross-Over Studies; Dermatitis, Atopic; Double- | 2001 |
Itch and atopic dermatitis: clinical and experimental studies.
Topics: Adolescent; Adult; Clemastine; Cyclosporine; Dermatitis, Atopic; Double-Blind Method; Female; Histam | 1991 |
The effects of antihistamines beyond H1 antagonism in allergic inflammation.
Topics: Benzhydryl Compounds; Cetirizine; Cyproheptadine; Dermatitis, Atopic; Histamine H1 Antagonists; Hist | 1990 |
The antipruritic effect of a sedative and a non-sedative antihistamine in atopic dermatitis.
Topics: Adolescent; Adult; Benzhydryl Compounds; Clemastine; Dermatitis, Atopic; Double-Blind Method; Female | 1990 |
Treatment of itching in atopic eczema with antihistamines with a low sedative profile.
Topics: Adolescent; Adult; Benzhydryl Compounds; Clinical Trials as Topic; Dermatitis, Atopic; Female; Hista | 1989 |
Failure of terfenadine in relieving the pruritus of atopic dermatitis.
Topics: Adolescent; Adult; Aged; Benzhydryl Compounds; Child; Dermatitis, Atopic; Double-Blind Method; Hista | 1989 |
[Terfenadine compared to clemastine in the treatment of pruriginous cutaneous diseases. Double-blind comparative study].
Topics: Adolescent; Adult; Aged; Benzhydryl Compounds; Clemastine; Clinical Trials as Topic; Dermatitis, Ato | 1987 |
Terfenadine in the treatment of chronic idiopathic urticaria and atopic dermatitis.
Topics: Adolescent; Adult; Aged; Benzhydryl Compounds; Chronic Disease; Clemastine; Dermatitis, Atopic; Doub | 1988 |
11 other studies available for terfenadine and Dermatitis, Atopic
| Article | Year |
|---|---|
Analysis of disease-dependent sedative profiles of H(1)-antihistamines by large-scale surveillance using the visual analog scale.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Asthma; Butyrophenones; Cetirizine; Child; Chlorpheniram | 2008 |
Leukotriene B(4) mediates sphingosylphosphorylcholine-induced itch-associated responses in mouse skin.
Topics: Animals; Calcium; Dermatitis, Atopic; Ganglia, Spinal; Histamine; Histamine H1 Antagonists, Non-Seda | 2009 |
Ameliorating effect of Yokukansan on the development of atopic dermatitis-like lesions and scratching behavior in socially isolated NC/Nga mice.
Topics: Animals; Anti-Anxiety Agents; Dermatitis, Atopic; Drugs, Chinese Herbal; Excitatory Amino Acid Trans | 2011 |
The various effects of four H1-antagonists on serum substance P levels in patients with atopic dermatitis.
Topics: Adult; Anti-Allergic Agents; Cetirizine; Dermatitis, Atopic; Dibenzazepines; Dibenzoxepins; E-Select | 2005 |
Pharmacological characterization of a chronic pruritus model induced by multiple application of 2,4,6-trinitrochlorobenzene in NC mice.
Topics: Animals; Antipruritics; Cell Degranulation; Chronic Disease; Cromolyn Sodium; Cyproheptadine; Dermat | 2007 |
[Linear dermatitis due to shiitake mushrooms].
Topics: Administration, Oral; Administration, Topical; Adult; Androstadienes; Anti-Allergic Agents; Dermatit | 2007 |
The effect of H1 receptor antagonists on peripheral blood mononuclear cells, adenoid cells and primary cell lines.
Topics: Adenoids; Adult; Cell Division; Cell Line; Chlorpheniramine; Dermatitis, Atopic; Dose-Response Relat | 1995 |
Effect of H1-antihistamines on histamine release from dispersed canine cutaneous mast cells.
Topics: Animals; Calcimycin; Cell Survival; Cetirizine; Concanavalin A; Dermatitis, Atopic; Dog Diseases; Do | 1997 |
Antihistamines for atopic dermatitis.
Topics: Adolescent; Adult; Aged; Antipruritics; Cetirizine; Child; Clemastine; Dermatitis, Atopic; Double-Bl | 2000 |
In vitro studies with fexofenadine, a new nonsedating histamine H1 receptor antagonist, on isolated human basophils.
Topics: Basophils; Dermatitis, Atopic; Enzyme Inhibitors; Histamine H1 Antagonists; Histamine Release; Human | 2000 |
Medication for the flight deck.
Topics: Advertising; Aerospace Medicine; Benzhydryl Compounds; Dermatitis, Atopic; Humans; Terfenadine; Trut | 1985 |