terfenadine has been researched along with Delayed Hypersensitivity in 9 studies
Terfenadine: A selective histamine H1-receptor antagonist devoid of central nervous system depressant activity. The drug was used for ALLERGY but withdrawn due to causing LONG QT SYNDROME.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Because the older antihistamines possessed relatively weak antihistaminic action, as well as sedative and anticholinergic effects, they could not be administered in doses high enough to confer relief to atopic patients with asthma." | 8.78 | Antihistamines in the treatment of clinical asthma. ( Rafferty, P, 1990) |
| "We have attempted to use a potent and selective histamine H1-receptor antagonist terfenadine to allow a larger dose of allergen to be administered to previous single early responders to investigate if an increased dose of allergen could induce a late asthmatic response." | 7.67 | The effect of an increase in inhaled allergen dose after terfenadine on the occurrence and magnitude of the late asthmatic response. ( Beasley, R; Holgate, ST; Lai, CK, 1989) |
| "Because the older antihistamines possessed relatively weak antihistaminic action, as well as sedative and anticholinergic effects, they could not be administered in doses high enough to confer relief to atopic patients with asthma." | 4.78 | Antihistamines in the treatment of clinical asthma. ( Rafferty, P, 1990) |
| "We have attempted to use a potent and selective histamine H1-receptor antagonist terfenadine to allow a larger dose of allergen to be administered to previous single early responders to investigate if an increased dose of allergen could induce a late asthmatic response." | 3.67 | The effect of an increase in inhaled allergen dose after terfenadine on the occurrence and magnitude of the late asthmatic response. ( Beasley, R; Holgate, ST; Lai, CK, 1989) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (33.33) | 18.7374 |
| 1990's | 4 (44.44) | 18.2507 |
| 2000's | 1 (11.11) | 29.6817 |
| 2010's | 1 (11.11) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Matsubara, R | 1 |
| Kumagai, K | 1 |
| Shigematsu, H | 1 |
| Kitaura, K | 1 |
| Nakasone, Y | 1 |
| Suzuki, S | 1 |
| Hamada, Y | 1 |
| Suzuki, R | 1 |
| de Weck, AL | 1 |
| Derer, T | 1 |
| Bischoff, SC | 1 |
| Takafuji, S | 1 |
| Simons, FE | 1 |
| Silver, NA | 1 |
| Gu, X | 1 |
| Simons, KJ | 1 |
| Hamid, M | 1 |
| Rafferty, P | 2 |
| Holgate, ST | 3 |
| Norval, M | 1 |
| Gilmour, JW | 1 |
| Simpson, TJ | 1 |
| Akagi, M | 1 |
| Mio, M | 1 |
| Miyoshi, K | 1 |
| Tasaka, K | 1 |
| Church, MM | 1 |
| Lai, C | 1 |
| Beasley, R | 2 |
| Featherstone, RL | 1 |
| Lai, CK | 1 |
1 review available for terfenadine and Delayed Hypersensitivity
| Article | Year |
|---|---|
Antihistamines in the treatment of clinical asthma.
Topics: Animals; Asthma; Benzhydryl Compounds; Cetirizine; Dose-Response Relationship, Drug; Forced Expirato | 1990 |
3 trials available for terfenadine and Delayed Hypersensitivity
| Article | Year |
|---|---|
The effect of terfenadine on the immediate and late-phase reactions mediated by immunoglobulin E.
Topics: Administration, Oral; Allergens; Antibodies, Anti-Idiotypic; Basophils; Candida albicans; Complement | 1993 |
Skin concentrations of H1-receptor antagonists.
Topics: Adult; Diphenhydramine; Double-Blind Method; Histamine H1 Antagonists; Humans; Hypersensitivity, Del | 2001 |
The inhibitory effect of terfenadine and flurbiprofen on early and late-phase bronchoconstriction following allergen challenge in atopic asthma.
Topics: Adolescent; Adult; Allergens; Asthma; Benzhydryl Compounds; Bronchial Provocation Tests; Female; Flu | 1990 |
5 other studies available for terfenadine and Delayed Hypersensitivity
| Article | Year |
|---|---|
Fexofenadine Suppresses Delayed-Type Hypersensitivity in the Murine Model of Palladium Allergy.
Topics: Allergens; Animals; Anti-Allergic Agents; Antigen-Presenting Cells; Biomarkers; Cytokines; Disease M | 2017 |
The effect of histamine receptor antagonists on immunosuppression induced by the cis-isomer of urocanic acid.
Topics: Adenosine Triphosphatases; Animals; Benzhydryl Compounds; Cell Count; Cimetidine; Female; Herpes Sim | 1990 |
Antiallergic effects of terfenadine on immediate type hypersensitivity reactions.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adenylyl Cyclases; Anaphylaxis; Animals; Asthma; Benzhydryl Com | 1987 |
The mediator and cellular basis of the allergic response.
Topics: Animals; Asthma; Benzhydryl Compounds; Cromolyn Sodium; Eosinophils; Guinea Pigs; Histamine H1 Antag | 1988 |
The effect of an increase in inhaled allergen dose after terfenadine on the occurrence and magnitude of the late asthmatic response.
Topics: Administration, Inhalation; Adult; Aged; Allergens; Asthma; Benzhydryl Compounds; Female; Forced Exp | 1989 |