terfenadine and Complications, Pregnancy studies

terfenadine and Complications, Pregnancy

Terfenadine: A selective histamine H1-receptor antagonist devoid of central nervous system depressant activity. The drug was used for ALLERGY but withdrawn due to causing LONG QT SYNDROME.

Research Excerpts

Excerpt	Relevance	Reference
"Fexofenadine hydrochloride is a frequently used drug for treatment of allergic conditions during pregnancy, but the fetal safety of fexofenadine use has not been well studied."	7.96	Association Between Fexofenadine Use During Pregnancy and Fetal Outcomes. ( Andersen, JT; Andersson, NW; Torp-Pedersen, C, 2020)
"Fexofenadine hydrochloride is a frequently used drug for treatment of allergic conditions during pregnancy, but the fetal safety of fexofenadine use has not been well studied."	3.96	Association Between Fexofenadine Use During Pregnancy and Fetal Outcomes. ( Andersen, JT; Andersson, NW; Torp-Pedersen, C, 2020)
"Fexofenadine is a well-identified in vivo probe substrate of P-glycoprotein (P-gp) and/or organic anion transporting polypeptide (OATP)."	1.62	Chiral Transplacental Pharmacokinetics of Fexofenadine: Impact of P-Glycoprotein Inhibitor Fluoxetine Using the Human Placental Perfusion Model. ( Bapat, P; Berger, H; de Carvalho Cavalli, R; de Lima Moreira, F; Koren, G; Lanchote, VL; Lubetsky, A; Pinto, L, 2021)

Research

Studies (3)

Timeframe	Studies, this research(%)	All Research%
pre-1990	1 (33.33)	18.7374
1990's	0 (0.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	2 (66.67)	2.80

Timeframe

Studies, this research(%)

All Research%

pre-1990

1 (33.33)

18.7374

1990's

0 (0.00)

18.2507

2000's

0 (0.00)

29.6817

2010's

0 (0.00)

24.3611

2020's

2 (66.67)

2.80

Authors

Authors	Studies
Andersson, NW	1
Torp-Pedersen, C	1
Andersen, JT	1
Pinto, L	1
Bapat, P	1
de Lima Moreira, F	1
Lubetsky, A	1
de Carvalho Cavalli, R	1
Berger, H	1
Lanchote, VL	1
Koren, G	1
Lantin, JP	1
Pécoud, A	1

Studies

Andersson, NW

Torp-Pedersen, C

Andersen, JT

Pinto, L

Bapat, P

de Lima Moreira, F

Lubetsky, A

de Carvalho Cavalli, R

Berger, H

Lanchote, VL

Koren, G

Lantin, JP

Pécoud, A

Other Studies

3 other studies available for terfenadine and Complications, Pregnancy

Article	Year
Association Between Fexofenadine Use During Pregnancy and Fetal Outcomes. JAMA pediatrics, 2020, 08-01, Volume: 174, Issue:8 Topics: Adult; Female; Follow-Up Studies; Histamine H1 Antagonists, Non-Sedating; Humans; Infant, Newborn; I	2020
Chiral Transplacental Pharmacokinetics of Fexofenadine: Impact of P-Glycoprotein Inhibitor Fluoxetine Using the Human Placental Perfusion Model. Pharmaceutical research, 2021, Volume: 38, Issue:4 Topics: Area Under Curve; ATP Binding Cassette Transporter, Subfamily B; Drug Interactions; Female; Fluoxeti	2021
[Optimal use of antihistaminics]. Revue medicale de la Suisse romande, 1989, Volume: 109, Issue:3 Topics: Astemizole; Asthma; Benzhydryl Compounds; Benzimidazoles; Female; Histamine H1 Antagonists; Humans;	1989

Article

Year

Association Between Fexofenadine Use During Pregnancy and Fetal Outcomes.

JAMA pediatrics, 2020, 08-01, Volume: 174, Issue:8

Topics: Adult; Female; Follow-Up Studies; Histamine H1 Antagonists, Non-Sedating; Humans; Infant, Newborn; I

2020

Chiral Transplacental Pharmacokinetics of Fexofenadine: Impact of P-Glycoprotein Inhibitor Fluoxetine Using the Human Placental Perfusion Model.

Pharmaceutical research, 2021, Volume: 38, Issue:4

Topics: Area Under Curve; ATP Binding Cassette Transporter, Subfamily B; Drug Interactions; Female; Fluoxeti

2021

[Optimal use of antihistaminics].

Revue medicale de la Suisse romande, 1989, Volume: 109, Issue:3

Topics: Astemizole; Asthma; Benzhydryl Compounds; Benzimidazoles; Female; Histamine H1 Antagonists; Humans;

1989