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terfenadine and Chronic Disease

terfenadine has been researched along with Chronic Disease in 49 studies

Terfenadine: A selective histamine H1-receptor antagonist devoid of central nervous system depressant activity. The drug was used for ALLERGY but withdrawn due to causing LONG QT SYNDROME.

Chronic Disease: Diseases which have one or more of the following characteristics: they are permanent, leave residual disability, are caused by nonreversible pathological alteration, require special training of the patient for rehabilitation, or may be expected to require a long period of supervision, observation, or care (Dictionary of Health Services Management, 2d ed). For epidemiological studies chronic disease often includes HEART DISEASES; STROKE; CANCER; and diabetes (DIABETES MELLITUS, TYPE 2).

Research Excerpts

ExcerptRelevanceReference
"H1-antihistamines are the first-line treatment of chronic idiopathic urticaria (CIU), but CIU is occasionally refractory to the conventional treatment doses."9.17Comparison of the efficacy of fexofenadine 120 and 240 mg/day on chronic idiopathic urticaria and histamine-induced skin responses in Japanese populations. ( Kabashima, K; Miyachi, Y; Nakahigashi, K; Tanizaki, H, 2013)
"The present study examined the impact of once-daily fexofenadine hydrochloride (HCl) 180 mg on health-related quality of life (HRQL) in subjects with chronic idiopathic urticaria (CIU)."9.12The effect of fexofenadine hydrochloride on productivity and quality of life in patients with chronic idiopathic urticaria. ( Harding, G; Leahy, MJ; Meeves, S; Shikiar, R; Spector, SL, 2007)
"This dose-finding study assessed the safety and efficacy of fexofenadine in chronic idiopathic urticaria."9.09Fexofenadine HCl is safe and effective for treatment of chronic idiopathic urticaria. ( Mason, J; Nelson, HS; Reynolds, R, 2000)
"The effect of 60 mg twice-daily fexofenadine HCl on health-related quality of life and productivity at work, in the classroom, and during daily activities in patients with moderate to severe chronic idiopathic urticaria symptoms was studied in two identical, 4-week, placebo-controlled, multicenter clinical trials."9.09Effect of 60 mg twice-daily fexofenadine HCl on quality of life, work and classroom productivity, and regular activity in patients with chronic idiopathic urticaria. ( Finn, AF; Schoenwetter, WF; Thompson, AK, 2000)
"In this 4-week, multicenter, placebo-controlled study, 439 patients with moderate to severe pruritus and urticaria received 1 of 4 oral doses of fexofenadine HCl (20, 60, 120, or 240 mg twice a day) or placebo."9.09A double-blind, placebo-controlled trial of fexofenadine HCl in the treatment of chronic idiopathic urticaria. ( Finn, AF; Fretwell, R; Kaplan, AP; Long, J; Qu, R, 1999)
"Ebastine is a new second generation histamine H1 receptor antagonist that has shown clinical efficacy in the treatment of seasonal and perennial allergic rhinitis and chronic urticaria after once-daily administration."9.08Double-blind multicentre comparative study of ebastine, terfenadine and placebo in the treatment of chronic idiopathic urticaria in adults. ( Kalis, B, 1996)
"Clinical trials of a new histamine H1-blocker of the III generation zyrtec (cetirizine) manufactured in Belgium (UCB) demonstrated its high efficacy in pollenosis and chronic idiopathic urticaria."9.07[The efficacy of the Zirtek (cetirizine) preparation in chronic recurrent urticaria and seasonal allergic rhinitis]. ( Androsov, VN; Belostotskaia, OI; Il'ina, NI, 1994)
"Our randomised study in parallel groups, double-blind double placebo, has compared the efficacy, onset of action and safety of terfenadine and cetirizine in chronic idiopathic urticaria."9.07[Double-blind comparative study of terfenadine and cetirizine in chronic idiopathic urticaria]. ( Bloom, M; Danglas, P; Hantzperg, M; Lambert, D, 1993)
"In a 20-d, double-blind, randomized, parallel study, the efficacy of cetirizine and terfenadine was compared in 30 patients with chronic idiopathic urticaria."9.07A comparison of the efficacy of cetirizine and terfenadine. A double-blind, controlled study of chronic idiopathic urticaria. ( Andri, G; Andri, L; Betteli, C; Givanni, S; Lombardi, C; Mezzelani, P; Senna, GE, 1993)
"Forty patients with chronic urticaria were treated with terfenadine or astemizole in a randomized double-blind study."9.06Comparative study of astemizole and terfenadine in the treatment of chronic idiopathic urticaria. A randomized double-blind study of 40 patients. ( Bödeker, RH; Paul, E, 1989)
"Results of a double-blind, randomized, placebo-controlled, parallel study in 37 patients indicate that terfenadine, 60 mg bid, is significantly more effective than placebo and as effective as hydroxyzine, 25 mg qid, in the treatment of chronic idiopathic urticaria without causing the somnolence that was associated with the use of hydroxyzine."9.06Double-blind, placebo-controlled study of terfenadine and hydroxyzine in patients with chronic idiopathic urticaria. ( Ball, R; Boggs, PB; Ellis, CN; Grossman, J; Gupta, AK; Shulan, D; Washburne, WF, 1989)
"The objective of these three double-blind multi-centre studies was to determine whether terfenadine 120 mg once daily has similar efficacy and tolerability as the standard dosage of 60 mg twice daily in the treatment of chronic urticaria."9.06Terfenadine once daily in chronic urticaria. A multi-centre double-blind comparison of terfenadine once daily versus twice daily. ( , 1989)
"The objective of this double-blind study, which is part of a multicenter study, was to determine whether terfenadine (120 mg once daily) has similar efficacy and tolerability to the standard dosage of 60 mg twice daily in the treatment of chronic urticaria."9.06Comparison of efficacy and tolerability of terfenadine administered once daily versus twice daily in patients with chronic idiopathic urticaria. ( Köhler, ME; Paul, E; Reinel, D; Ulrich, R, 1989)
"Patients (n = 56) with a diagnosis of chronic idiopathic urticaria were assessed in a fully randomized, double-blind, crossover study to investigate the efficacy of acrivastine at two doses (8 and 4 mg) versus 60 mg terfenadine and placebo administered three times daily."9.06A comparison of acrivastine versus terfenadine and placebo in the treatment of chronic idiopathic urticaria. ( Blog, FB; den Boer, MS; Gibson, JR; Harvey, SG; Jansen, FC; Kuneman, JJ; Starink, TM; van Joost, T; Westerhof, W, 1989)
"The efficacy of terfenadine, a nonsedating H1 antihistamine, in the management of chronic idiopathic urticaria was compared with chlorpheniramine and placebo in a parallel multicenter trial."9.06Double-blind comparison of terfenadine, chlorpheniramine, and placebo in the treatment of chronic idiopathic urticaria. ( Bernstein, DI; Buckley, CE; Chu, T; Fox, RW; Grant, JA; Rocklin, RE; Schoenwetter, WF; Spector, SL; Stafford, CT; Stroh, JE, 1988)
"The use of the nonsedating antihistamine terfenadine (60 mg twice daily) in the treatment of chronic idiopathic urticaria and contact urticaria associated with atopic dermatitis was assessed."9.06Terfenadine in the treatment of chronic idiopathic urticaria and atopic dermatitis. ( Hjorth, N, 1988)
"Two new non-sedating antihistamines, astemizole (10 mg per day) and terfenadine (120 mg per day), were compared in a double-blind randomized study in 42 adult patients suffering from chronic urticaria."9.06Double-blind comparison of astemizole and terfenadine in the treatment of chronic urticaria. ( Cainelli, T; Mosca, M; Seidenari, S; Valsecchi, R, 1986)
"45 patients with chronic urticaria were randomized to double blind therapy with terfenadine an H1-antihistamine or ranitidine, an H2-antihistamine, or a combination of both drugs."9.06Treatment of chronic urticaria with terfenadine and ranitidine. A randomized double-blind study in 45 patients. ( Bödeker, RH; Paul, E, 1986)
"40 patients suffering from chronic urticaria were randomly treated with either Terfenadine or Astemizole."9.05[Comparison of astemizole and terfenadine in the treatment of chronic urticaria. A randomized double-blind study of 40 patients]. ( Bödeker, RH; Paul, E, 1985)
"Terfenadine, a potent and non-sedative antihistamine, was shown to be effective in chronic idiopathic urticaria in a double-blind crossover placebo controlled trial."9.05Terfenadine and placebo compared in the treatment of chronic idiopathic urticaria: a randomised double-blind study. ( Ferguson, J; Kenicer, KJ; MacDonald, KJ, 1985)
"fexofenadine is clinically effective in the treatment of seasonal allergic rhinitis and chronic idiopathic urticaria for which it is a suitable option for first-line therapy."7.70Fexofenadine: a review of its use in the management of seasonal allergic rhinitis and chronic idiopathic urticaria. ( Jarvis, B; Simpson, K, 2000)
"To evaluate the efficacy and safety of once-daily dosing of fexofenadine hydrochloride, 180 mg, on CIU."6.71Once-daily fexofenadine treatment for chronic idiopathic urticaria: a multicenter, randomized, double-blind, placebo-controlled study. ( Georges, G; Kaplan, AP; Liao, Y; Meeves, S; Spector, SL; Varghese, ST, 2005)
"Fexofenadine 180 mg is a new antihistamine that is effective in the treatment of chronic urticaria and that has a profile of side effects similar to placebo."6.70[Chronic idiopathic urticaria: effectiveness of fexofenadine. A double-blind, placebo controlled study with 21 patients]. ( Bircher, A; Degonda, M; Helbling, A; Pichler, WJ, 2002)
" Adverse events occurred in 20 cases (18."6.70Multicenter study of the efficacy and safety of fexofenadine 60 mg. twice daily in 108 Thai patients with chronic idiopathic urticaria. ( Aunhachoke, K; Charuwichitratana, S; Gherunpong, N; Gritiyarangsan, P; Janjumratsang, P; Jiamton, S; Korkij, W; Krisadapong, J; Kullavanijaya, P; Kulthanan, K; Kuntiranont, M; Sitakalin, C, 2001)
"Loratadine is a new selective peripheral histamine H1-receptor antagonist, that is orally effective, long-acting, and devoid of significant central and autonomic nervous system activity."6.67Comparative effects of loratadine and terfenadine in the treatment of chronic idiopathic urticaria. ( Belaich, S; Bruttmann, G; DeGreef, H; Lachapelle, JM; Paul, E; Pedrali, P; Tennstedt, D, 1990)
"Total 100 patients of chronic idiopathic urticaria aged 18 years and above with exclusion and inclusion criteria were selected."5.56Efficacy of Fexofenadine in the Treatment of Chronic Idiopathic Urticaria. ( Akhter, F; Jahan, H; Nandi, AK, 2020)
"H1-antihistamines are the first-line treatment of chronic idiopathic urticaria (CIU), but CIU is occasionally refractory to the conventional treatment doses."5.17Comparison of the efficacy of fexofenadine 120 and 240 mg/day on chronic idiopathic urticaria and histamine-induced skin responses in Japanese populations. ( Kabashima, K; Miyachi, Y; Nakahigashi, K; Tanizaki, H, 2013)
"The present study examined the impact of once-daily fexofenadine hydrochloride (HCl) 180 mg on health-related quality of life (HRQL) in subjects with chronic idiopathic urticaria (CIU)."5.12The effect of fexofenadine hydrochloride on productivity and quality of life in patients with chronic idiopathic urticaria. ( Harding, G; Leahy, MJ; Meeves, S; Shikiar, R; Spector, SL, 2007)
"In this 4-week, multicenter, placebo-controlled study, 439 patients with moderate to severe pruritus and urticaria received 1 of 4 oral doses of fexofenadine HCl (20, 60, 120, or 240 mg twice a day) or placebo."5.09A double-blind, placebo-controlled trial of fexofenadine HCl in the treatment of chronic idiopathic urticaria. ( Finn, AF; Fretwell, R; Kaplan, AP; Long, J; Qu, R, 1999)
"This dose-finding study assessed the safety and efficacy of fexofenadine in chronic idiopathic urticaria."5.09Fexofenadine HCl is safe and effective for treatment of chronic idiopathic urticaria. ( Mason, J; Nelson, HS; Reynolds, R, 2000)
"The effect of 60 mg twice-daily fexofenadine HCl on health-related quality of life and productivity at work, in the classroom, and during daily activities in patients with moderate to severe chronic idiopathic urticaria symptoms was studied in two identical, 4-week, placebo-controlled, multicenter clinical trials."5.09Effect of 60 mg twice-daily fexofenadine HCl on quality of life, work and classroom productivity, and regular activity in patients with chronic idiopathic urticaria. ( Finn, AF; Schoenwetter, WF; Thompson, AK, 2000)
"Ebastine is a new second generation histamine H1 receptor antagonist that has shown clinical efficacy in the treatment of seasonal and perennial allergic rhinitis and chronic urticaria after once-daily administration."5.08Double-blind multicentre comparative study of ebastine, terfenadine and placebo in the treatment of chronic idiopathic urticaria in adults. ( Kalis, B, 1996)
"Our randomised study in parallel groups, double-blind double placebo, has compared the efficacy, onset of action and safety of terfenadine and cetirizine in chronic idiopathic urticaria."5.07[Double-blind comparative study of terfenadine and cetirizine in chronic idiopathic urticaria]. ( Bloom, M; Danglas, P; Hantzperg, M; Lambert, D, 1993)
"Clinical trials of a new histamine H1-blocker of the III generation zyrtec (cetirizine) manufactured in Belgium (UCB) demonstrated its high efficacy in pollenosis and chronic idiopathic urticaria."5.07[The efficacy of the Zirtek (cetirizine) preparation in chronic recurrent urticaria and seasonal allergic rhinitis]. ( Androsov, VN; Belostotskaia, OI; Il'ina, NI, 1994)
"In a 20-d, double-blind, randomized, parallel study, the efficacy of cetirizine and terfenadine was compared in 30 patients with chronic idiopathic urticaria."5.07A comparison of the efficacy of cetirizine and terfenadine. A double-blind, controlled study of chronic idiopathic urticaria. ( Andri, G; Andri, L; Betteli, C; Givanni, S; Lombardi, C; Mezzelani, P; Senna, GE, 1993)
"Ten patients with stable chronic asthma completed a randomized double-blind placebo controlled crossover study examining the effect of 120mg terfenadine twice daily for 4 weeks on bronchial responsiveness."5.07Lack of effect of 4 weeks of oral H1 antagonist on bronchial responsiveness. ( Latimer, KM; Ruffin, RE, 1991)
"Forty patients with chronic urticaria were treated with terfenadine or astemizole in a randomized double-blind study."5.06Comparative study of astemizole and terfenadine in the treatment of chronic idiopathic urticaria. A randomized double-blind study of 40 patients. ( Bödeker, RH; Paul, E, 1989)
"Patients (n = 56) with a diagnosis of chronic idiopathic urticaria were assessed in a fully randomized, double-blind, crossover study to investigate the efficacy of acrivastine at two doses (8 and 4 mg) versus 60 mg terfenadine and placebo administered three times daily."5.06A comparison of acrivastine versus terfenadine and placebo in the treatment of chronic idiopathic urticaria. ( Blog, FB; den Boer, MS; Gibson, JR; Harvey, SG; Jansen, FC; Kuneman, JJ; Starink, TM; van Joost, T; Westerhof, W, 1989)
"The objective of this double-blind study, which is part of a multicenter study, was to determine whether terfenadine (120 mg once daily) has similar efficacy and tolerability to the standard dosage of 60 mg twice daily in the treatment of chronic urticaria."5.06Comparison of efficacy and tolerability of terfenadine administered once daily versus twice daily in patients with chronic idiopathic urticaria. ( Köhler, ME; Paul, E; Reinel, D; Ulrich, R, 1989)
"The objective of these three double-blind multi-centre studies was to determine whether terfenadine 120 mg once daily has similar efficacy and tolerability as the standard dosage of 60 mg twice daily in the treatment of chronic urticaria."5.06Terfenadine once daily in chronic urticaria. A multi-centre double-blind comparison of terfenadine once daily versus twice daily. ( , 1989)
"Results of a double-blind, randomized, placebo-controlled, parallel study in 37 patients indicate that terfenadine, 60 mg bid, is significantly more effective than placebo and as effective as hydroxyzine, 25 mg qid, in the treatment of chronic idiopathic urticaria without causing the somnolence that was associated with the use of hydroxyzine."5.06Double-blind, placebo-controlled study of terfenadine and hydroxyzine in patients with chronic idiopathic urticaria. ( Ball, R; Boggs, PB; Ellis, CN; Grossman, J; Gupta, AK; Shulan, D; Washburne, WF, 1989)
"45 patients with chronic urticaria were randomized to double blind therapy with terfenadine an H1-antihistamine or ranitidine, an H2-antihistamine, or a combination of both drugs."5.06Treatment of chronic urticaria with terfenadine and ranitidine. A randomized double-blind study in 45 patients. ( Bödeker, RH; Paul, E, 1986)
"The use of the nonsedating antihistamine terfenadine (60 mg twice daily) in the treatment of chronic idiopathic urticaria and contact urticaria associated with atopic dermatitis was assessed."5.06Terfenadine in the treatment of chronic idiopathic urticaria and atopic dermatitis. ( Hjorth, N, 1988)
"The efficacy of terfenadine, a nonsedating H1 antihistamine, in the management of chronic idiopathic urticaria was compared with chlorpheniramine and placebo in a parallel multicenter trial."5.06Double-blind comparison of terfenadine, chlorpheniramine, and placebo in the treatment of chronic idiopathic urticaria. ( Bernstein, DI; Buckley, CE; Chu, T; Fox, RW; Grant, JA; Rocklin, RE; Schoenwetter, WF; Spector, SL; Stafford, CT; Stroh, JE, 1988)
"Two new non-sedating antihistamines, astemizole (10 mg per day) and terfenadine (120 mg per day), were compared in a double-blind randomized study in 42 adult patients suffering from chronic urticaria."5.06Double-blind comparison of astemizole and terfenadine in the treatment of chronic urticaria. ( Cainelli, T; Mosca, M; Seidenari, S; Valsecchi, R, 1986)
"Terfenadine, a potent and non-sedative antihistamine, was shown to be effective in chronic idiopathic urticaria in a double-blind crossover placebo controlled trial."5.05Terfenadine and placebo compared in the treatment of chronic idiopathic urticaria: a randomised double-blind study. ( Ferguson, J; Kenicer, KJ; MacDonald, KJ, 1985)
"40 patients suffering from chronic urticaria were randomly treated with either Terfenadine or Astemizole."5.05[Comparison of astemizole and terfenadine in the treatment of chronic urticaria. A randomized double-blind study of 40 patients]. ( Bödeker, RH; Paul, E, 1985)
"It has been difficult to experimentally reproduce synergistic effects of ketoconazole on terfenadine-induced torsade de pointes."3.96Utilization of the chronic atrioventricular block cynomolgus monkey as an in vivo model to evaluate drug interaction-associated torsade de pointes. ( Chiba, K; Goto, A; Hagiwara-Nagasawa, M; Izumi-Nakaseko, H; Kambayashi, R; Matsumoto, A; Nunoi, Y; Sakamoto, K; Sugiyama, A, 2020)
"fexofenadine is clinically effective in the treatment of seasonal allergic rhinitis and chronic idiopathic urticaria for which it is a suitable option for first-line therapy."3.70Fexofenadine: a review of its use in the management of seasonal allergic rhinitis and chronic idiopathic urticaria. ( Jarvis, B; Simpson, K, 2000)
"To evaluate the efficacy and safety of once-daily dosing of fexofenadine hydrochloride, 180 mg, on CIU."2.71Once-daily fexofenadine treatment for chronic idiopathic urticaria: a multicenter, randomized, double-blind, placebo-controlled study. ( Georges, G; Kaplan, AP; Liao, Y; Meeves, S; Spector, SL; Varghese, ST, 2005)
"Fexofenadine 180 mg is a new antihistamine that is effective in the treatment of chronic urticaria and that has a profile of side effects similar to placebo."2.70[Chronic idiopathic urticaria: effectiveness of fexofenadine. A double-blind, placebo controlled study with 21 patients]. ( Bircher, A; Degonda, M; Helbling, A; Pichler, WJ, 2002)
" Adverse events occurred in 20 cases (18."2.70Multicenter study of the efficacy and safety of fexofenadine 60 mg. twice daily in 108 Thai patients with chronic idiopathic urticaria. ( Aunhachoke, K; Charuwichitratana, S; Gherunpong, N; Gritiyarangsan, P; Janjumratsang, P; Jiamton, S; Korkij, W; Krisadapong, J; Kullavanijaya, P; Kulthanan, K; Kuntiranont, M; Sitakalin, C, 2001)
"Treatment with hydroxyzine in patients with CU improved the clinical symptoms and modified the profile of HR; more histamine was recovered at 1 hour (p less than 0."2.67Effects of H1-antihistamine drug regimen on histamine release by nonlesional skin mast cells of patients with chronic urticaria. ( Bédard, PM; Brunet, C; Hébert, J, 1990)
"Loratadine was safe and well tolerated."2.67Comparative study of the efficacy and safety of loratadine syrup and terfenadine suspension in the treatment of chronic allergic skin diseases in a pediatric population. ( Cerio, R; Chieira, ML; deGroot, LJ; Giannetti, A; Gonçalves, HM; Guillot, B; Lutsky, BN; Lynde, CW; Schuller, JL; Vareltzides, A, 1993)
"Loratadine is a new selective peripheral histamine H1-receptor antagonist, that is orally effective, long-acting, and devoid of significant central and autonomic nervous system activity."2.67Comparative effects of loratadine and terfenadine in the treatment of chronic idiopathic urticaria. ( Belaich, S; Bruttmann, G; DeGreef, H; Lachapelle, JM; Paul, E; Pedrali, P; Tennstedt, D, 1990)
"Total 100 patients of chronic idiopathic urticaria aged 18 years and above with exclusion and inclusion criteria were selected."1.56Efficacy of Fexofenadine in the Treatment of Chronic Idiopathic Urticaria. ( Akhter, F; Jahan, H; Nandi, AK, 2020)

Research

Studies (49)

TimeframeStudies, this research(%)All Research%
pre-199015 (30.61)18.7374
1990's14 (28.57)18.2507
2000's15 (30.61)29.6817
2010's3 (6.12)24.3611
2020's2 (4.08)2.80

Authors

AuthorsStudies
Goto, A1
Sakamoto, K1
Hagiwara-Nagasawa, M1
Kambayashi, R1
Chiba, K1
Nunoi, Y1
Izumi-Nakaseko, H1
Matsumoto, A1
Sugiyama, A1
Jahan, H1
Akhter, F1
Nandi, AK1
Tanizaki, H2
Nakahigashi, K1
Miyachi, Y2
Kabashima, K2
Koh, SJ1
Kim, JW1
Kim, BG1
Lee, KL1
Chun, J1
Kim, JS1
Yamamoto, Y1
Nakamizo, S1
Otsuka, A1
Chowdhury, BA1
Cassano, N1
Filotico, R1
D'Argento, V1
Filieri, M1
Coviello, C1
Vena, G1
Kawashima, M1
Harada, S1
Tango, T1
Lennox, RD2
Leahy, MJ2
Shikiar, R2
Harding, G2
Leahy, M1
Kaplan, AP2
Spector, SL3
Meeves, S2
Liao, Y1
Varghese, ST1
Georges, G1
Yamashita, H1
Makino, T1
Mizukami, H1
Nose, M1
Neumann, Y1
Wood-Baker, R1
Smith, R1
Holgate, ST1
Androsov, VN1
Belostotskaia, OI1
Il'ina, NI1
Lutsky, BN1
Schuller, JL1
Cerio, R1
Chieira, ML1
Giannetti, A1
Gonçalves, HM1
deGroot, LJ1
Vareltzides, A1
Guillot, B1
Lynde, CW1
Lambert, D1
Hantzperg, M1
Danglas, P1
Bloom, M1
Andri, L1
Senna, GE1
Betteli, C1
Givanni, S1
Andri, G1
Lombardi, C1
Mezzelani, P1
Kalis, B1
Finn, AF2
Fretwell, R1
Qu, R1
Long, J1
Simpson, K1
Jarvis, B1
Nelson, HS1
Reynolds, R1
Mason, J1
Thompson, AK1
Schoenwetter, WF2
Nettis, E1
Dambra, P1
D'Oronzio, L1
Loria, MP1
Ferrannini, A1
Tursi, A1
Amichai, B1
Grunwald, MH1
Brenner, L1
Kulthanan, K1
Gritiyarangsan, P1
Sitakalin, C1
Charuwichitratana, S1
Korkij, W1
Aunhachoke, K1
Janjumratsang, P1
Jiamton, S1
Kuntiranont, M1
Krisadapong, J1
Gherunpong, N1
Kullavanijaya, P1
Degonda, M1
Pichler, WJ1
Bircher, A1
Helbling, A1
Abu Shareeah, AM1
Ciprandi, G1
Tosca, MA1
Iudice, A1
Buscaglia, S1
Fasce, L1
Canonica, GW1
Ruffin, RE1
Latimer, KM1
Brunet, C1
Bédard, PM1
Hébert, J1
Belaich, S1
Bruttmann, G1
DeGreef, H1
Lachapelle, JM1
Paul, E5
Pedrali, P1
Tennstedt, D1
Kietzmann, H1
Macher, E1
Rihoux, JP1
Ghys, L1
Bödeker, RH3
van Joost, T1
Blog, FB1
Westerhof, W1
Jansen, FC1
Starink, TM1
den Boer, MS1
Kuneman, JJ1
Harvey, SG1
Gibson, JR1
Reinel, D1
Ulrich, R1
Köhler, ME1
Boggs, PB1
Ellis, CN1
Grossman, J1
Washburne, WF1
Gupta, AK1
Ball, R1
Shulan, D1
Cainelli, T1
Seidenari, S1
Valsecchi, R1
Mosca, M1
Salisbury, J1
Bor, S1
Blair, C1
Shuster, S1
Hjorth, N1
Grant, JA1
Bernstein, DI1
Buckley, CE1
Chu, T1
Fox, RW1
Rocklin, RE1
Stafford, CT1
Stroh, JE1
Lembo, G1
Raulo, U1
Cantelli, V1
Patruno, C1
Ferguson, J1
MacDonald, KJ1
Kenicer, KJ1

Reviews

2 reviews available for terfenadine and Chronic Disease

ArticleYear
Review of fexofenadine in the treatment of chronic idiopathic urticaria.
    International journal of dermatology, 2002, Volume: 41, Issue:10

    Topics: Anti-Allergic Agents; Asia; Chronic Disease; Humans; North America; Terfenadine; Urticaria

2002
Fexofenadine hydrochloride--a new anti-histaminic drug.
    The Israel Medical Association journal : IMAJ, 2001, Volume: 3, Issue:3

    Topics: Chronic Disease; Clinical Trials as Topic; Drug Interactions; Histamine H1 Antagonists; Humans; Pati

2001

Trials

35 trials available for terfenadine and Chronic Disease

ArticleYear
Comparison of the efficacy of fexofenadine 120 and 240 mg/day on chronic idiopathic urticaria and histamine-induced skin responses in Japanese populations.
    The Journal of dermatological treatment, 2013, Volume: 24, Issue:6

    Topics: Adult; Chronic Disease; Cross-Over Studies; Double-Blind Method; Female; Histamine; Histamine H1 Ant

2013
Comparison of the efficacy of olopatadine and fexofenadine in chronic idiopathic urticaria patients: a crossover study.
    Pharmacology, 2015, Volume: 95, Issue:1-2

    Topics: Adult; Anti-Allergic Agents; Chronic Disease; Cross-Over Studies; Dibenzoxepins; Female; Histamine H

2015
Validation of the Dermatology Life Quality Index as an outcome measure for urticaria-related quality of life.
    Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 2004, Volume: 93, Issue:2

    Topics: Chronic Disease; Dermatology; Dose-Response Relationship, Drug; Double-Blind Method; Histamine H1 An

2004
Once-daily fexofenadine treatment for chronic idiopathic urticaria: a multicenter, randomized, double-blind, placebo-controlled study.
    Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 2005, Volume: 94, Issue:6

    Topics: Adolescent; Child; Chronic Disease; Double-Blind Method; Female; Humans; Male; Terfenadine; Urticari

2005
The effect of fexofenadine hydrochloride on productivity and quality of life in patients with chronic idiopathic urticaria.
    Cutis, 2007, Volume: 79, Issue:2

    Topics: Adolescent; Chronic Disease; Double-Blind Method; Efficiency; Female; Histamine H1 Antagonists, Non-

2007
[Antihistaminic therapy of chronic urticaria. Results of a multicenter study with azatadine and terfenadine].
    Fortschritte der Medizin, 1984, Oct-11, Volume: 102, Issue:38

    Topics: Adult; Benzhydryl Compounds; Chronic Disease; Clinical Trials as Topic; Cyproheptadine; Female; Hist

1984
A double-blind, placebo controlled study of the effect of the specific histamine H1-receptor antagonist, terfenadine, in chronic severe asthma.
    British journal of clinical pharmacology, 1995, Volume: 39, Issue:6

    Topics: Adult; Analysis of Variance; Asthma; Chronic Disease; Cross-Over Studies; Double-Blind Method; Femal

1995
[The efficacy of the Zirtek (cetirizine) preparation in chronic recurrent urticaria and seasonal allergic rhinitis].
    Terapevticheskii arkhiv, 1994, Volume: 66, Issue:11

    Topics: Adolescent; Adult; Cetirizine; Chronic Disease; Drug Therapy, Combination; Female; Humans; Male; Mid

1994
Comparative study of the efficacy and safety of loratadine syrup and terfenadine suspension in the treatment of chronic allergic skin diseases in a pediatric population.
    Arzneimittel-Forschung, 1993, Volume: 43, Issue:11

    Topics: Child; Chronic Disease; Dermatitis, Contact; Humans; Loratadine; Skin; Solutions; Suspensions; Terfe

1993
[Double-blind comparative study of terfenadine and cetirizine in chronic idiopathic urticaria].
    Allergie et immunologie, 1993, Volume: 25, Issue:6

    Topics: Adolescent; Adult; Cetirizine; Child; Chronic Disease; Double-Blind Method; Female; Humans; Male; Mi

1993
A comparison of the efficacy of cetirizine and terfenadine. A double-blind, controlled study of chronic idiopathic urticaria.
    Allergy, 1993, Volume: 48, Issue:5

    Topics: Adult; Cetirizine; Chronic Disease; Double-Blind Method; Humans; Terfenadine; Urticaria

1993
Double-blind multicentre comparative study of ebastine, terfenadine and placebo in the treatment of chronic idiopathic urticaria in adults.
    Drugs, 1996, Volume: 52 Suppl 1

    Topics: Adult; Anti-Allergic Agents; Butyrophenones; Chronic Disease; Double-Blind Method; Histamine H1 Anta

1996
A double-blind, placebo-controlled trial of fexofenadine HCl in the treatment of chronic idiopathic urticaria.
    The Journal of allergy and clinical immunology, 1999, Volume: 104, Issue:5

    Topics: Adolescent; Adult; Aged; Child; Chronic Disease; Double-Blind Method; Female; Histamine H1 Antagonis

1999
Fexofenadine HCl is safe and effective for treatment of chronic idiopathic urticaria.
    Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 2000, Volume: 84, Issue:5

    Topics: Adolescent; Adult; Aged; Anti-Allergic Agents; Child; Chronic Disease; Disorders of Excessive Somnol

2000
Effect of 60 mg twice-daily fexofenadine HCl on quality of life, work and classroom productivity, and regular activity in patients with chronic idiopathic urticaria.
    Journal of the American Academy of Dermatology, 2000, Volume: 43, Issue:1 Pt 1

    Topics: Adolescent; Adult; Aged; Chronic Disease; Female; Histamine H1 Antagonists; Humans; Male; Middle Age

2000
Comparison of montelukast and fexofenadine for chronic idiopathic urticaria.
    Archives of dermatology, 2001, Volume: 137, Issue:1

    Topics: Acetates; Adult; Aged; Chronic Disease; Cyclopropanes; Double-Blind Method; Female; Histamine H1 Ant

2001
Multicenter study of the efficacy and safety of fexofenadine 60 mg. twice daily in 108 Thai patients with chronic idiopathic urticaria.
    Journal of the Medical Association of Thailand = Chotmaihet thangphaet, 2001, Volume: 84, Issue:2

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Chronic Disease; Female; Histamine H1 Antagonists; Human

2001
[Chronic idiopathic urticaria: effectiveness of fexofenadine. A double-blind, placebo controlled study with 21 patients].
    Praxis, 2002, Apr-10, Volume: 91, Issue:15

    Topics: Adult; Aged; Anti-Allergic Agents; Chronic Disease; Double-Blind Method; Female; Humans; Male; Middl

2002
Comparative efficacy of loratadine and terfenadine in the treatment of chronic idiopathic urticaria.
    International journal of dermatology, 1992, Volume: 31, Issue:5

    Topics: Adult; Chronic Disease; Cyproheptadine; Female; Histamine Antagonists; Humans; Loratadine; Male; Pru

1992
Lack of effect of 4 weeks of oral H1 antagonist on bronchial responsiveness.
    The European respiratory journal, 1991, Volume: 4, Issue:5

    Topics: Administration, Oral; Adult; Asthma; Bronchoconstriction; Chronic Disease; Double-Blind Method; Drug

1991
Effects of H1-antihistamine drug regimen on histamine release by nonlesional skin mast cells of patients with chronic urticaria.
    The Journal of allergy and clinical immunology, 1990, Volume: 86, Issue:5

    Topics: Adult; Benzhydryl Compounds; Chronic Disease; Double-Blind Method; Female; Histamine H1 Antagonists;

1990
Comparative effects of loratadine and terfenadine in the treatment of chronic idiopathic urticaria.
    Annals of allergy, 1990, Volume: 64, Issue:2 Pt 2

    Topics: Adolescent; Adult; Aged; Benzhydryl Compounds; Chronic Disease; Clinical Trials as Topic; Cyprohepta

1990
Comparison of cetirizine and terfenadine in the treatment of chronic idiopathic urticaria.
    Annals of allergy, 1990, Volume: 65, Issue:6

    Topics: Benzhydryl Compounds; Cetirizine; Chronic Disease; Double-Blind Method; Histamine H1 Antagonists; Hu

1990
Comparative study of astemizole and terfenadine in the treatment of chronic idiopathic urticaria. A randomized double-blind study of 40 patients.
    Annals of allergy, 1989, Volume: 62, Issue:4

    Topics: Astemizole; Benzhydryl Compounds; Benzimidazoles; Chronic Disease; Clinical Trials as Topic; Double-

1989
A comparison of acrivastine versus terfenadine and placebo in the treatment of chronic idiopathic urticaria.
    The Journal of international medical research, 1989, Volume: 17 Suppl 2

    Topics: Adult; Benzhydryl Compounds; Chronic Disease; Clinical Trials as Topic; Double-Blind Method; Female;

1989
Comparison of efficacy and tolerability of terfenadine administered once daily versus twice daily in patients with chronic idiopathic urticaria.
    Annals of allergy, 1989, Volume: 63, Issue:4

    Topics: Benzhydryl Compounds; Chronic Disease; Double-Blind Method; Drug Administration Schedule; Histamine

1989
Terfenadine once daily in chronic urticaria. A multi-centre double-blind comparison of terfenadine once daily versus twice daily.
    Allergy, 1989, Volume: 44, Issue:7

    Topics: Adult; Benzhydryl Compounds; Chronic Disease; Double-Blind Method; Drug Administration Schedule; Fem

1989
Double-blind, placebo-controlled study of terfenadine and hydroxyzine in patients with chronic idiopathic urticaria.
    Annals of allergy, 1989, Volume: 63, Issue:6 Pt 2

    Topics: Adolescent; Adult; Benzhydryl Compounds; Chronic Disease; Double-Blind Method; Histamine H1 Antagoni

1989
[Comparison of astemizole and terfenadine in the treatment of chronic urticaria. A randomized double-blind study of 40 patients].
    Zeitschrift fur Hautkrankheiten, 1985, Volume: 60 Suppl 1

    Topics: Astemizole; Benzhydryl Compounds; Benzimidazoles; Chronic Disease; Clinical Trials as Topic; Double-

1985
Treatment of chronic urticaria with terfenadine and ranitidine. A randomized double-blind study in 45 patients.
    European journal of clinical pharmacology, 1986, Volume: 31, Issue:3

    Topics: Adult; Aged; Benzhydryl Compounds; Chronic Disease; Double-Blind Method; Drug Therapy, Combination;

1986
Double-blind comparison of astemizole and terfenadine in the treatment of chronic urticaria.
    Pharmatherapeutica, 1986, Volume: 4, Issue:10

    Topics: Adolescent; Adult; Astemizole; Benzhydryl Compounds; Benzimidazoles; Chronic Disease; Double-Blind M

1986
A double-blind placebo controlled study of terfenadine in the treatment of chronic idiopathic urticaria.
    The British journal of clinical practice, 1987, Volume: 41, Issue:8

    Topics: Adolescent; Adult; Aged; Benzhydryl Compounds; Chronic Disease; Clinical Trials as Topic; Double-Bli

1987
Terfenadine in the treatment of chronic idiopathic urticaria and atopic dermatitis.
    Cutis, 1988, Oct-27, Volume: 42, Issue:4A

    Topics: Adolescent; Adult; Aged; Benzhydryl Compounds; Chronic Disease; Clemastine; Dermatitis, Atopic; Doub

1988
Double-blind comparison of terfenadine, chlorpheniramine, and placebo in the treatment of chronic idiopathic urticaria.
    The Journal of allergy and clinical immunology, 1988, Volume: 81, Issue:3

    Topics: Adolescent; Adult; Benzhydryl Compounds; Chlorpheniramine; Chronic Disease; Clinical Trials as Topic

1988
Terfenadine and placebo compared in the treatment of chronic idiopathic urticaria: a randomised double-blind study.
    British journal of clinical pharmacology, 1985, Volume: 20, Issue:6

    Topics: Adult; Aged; Benzhydryl Compounds; Chronic Disease; Clinical Trials as Topic; Double-Blind Method; F

1985

Other Studies

12 other studies available for terfenadine and Chronic Disease

ArticleYear
Utilization of the chronic atrioventricular block cynomolgus monkey as an in vivo model to evaluate drug interaction-associated torsade de pointes.
    Journal of pharmacological sciences, 2020, Volume: 142, Issue:4

    Topics: Animals; Atrioventricular Block; Chronic Disease; Disease Models, Animal; Drug Synergism; Ketoconazo

2020
Efficacy of Fexofenadine in the Treatment of Chronic Idiopathic Urticaria.
    Mymensingh medical journal : MMJ, 2020, Volume: 29, Issue:2

    Topics: Adolescent; Bangladesh; Chronic Disease; Chronic Urticaria; Double-Blind Method; Humans; Terfenadine

2020
Fexofenadine regulates nuclear factor-κB signaling and endoplasmic reticulum stress in intestinal epithelial cells and ameliorates acute and chronic colitis in mice.
    The Journal of pharmacology and experimental therapeutics, 2015, Volume: 352, Issue:3

    Topics: Acute Disease; Animals; Chronic Disease; Colitis; Endoplasmic Reticulum Stress; Female; HCT116 Cells

2015
Chronic urticaria and angioedema.
    The New England journal of medicine, 2002, Jul-18, Volume: 347, Issue:3

    Topics: Angioedema; Chronic Disease; Histamine H1 Antagonists; Humans; Terfenadine; Urticaria

2002
In vivo anti-inflammatory effects of fexofenadine in chronic idiopathic urticaria.
    Journal of the European Academy of Dermatology and Venereology : JEADV, 2002, Volume: 16, Issue:4

    Topics: Adolescent; Adult; Biopsy, Needle; Case-Control Studies; Chronic Disease; Culture Techniques; E-Sele

2002
Minimal important difference (MID) of the Dermatology Life Quality Index (DLQI): results from patients with chronic idiopathic urticaria.
    Health and quality of life outcomes, 2005, May-20, Volume: 3

    Topics: Adolescent; Adult; Aged; Child; Chronic Disease; Clinical Trials, Phase III as Topic; Data Interpret

2005
Pharmacological characterization of a chronic pruritus model induced by multiple application of 2,4,6-trinitrochlorobenzene in NC mice.
    European journal of pharmacology, 2007, Jun-01, Volume: 563, Issue:1-3

    Topics: Animals; Antipruritics; Cell Degranulation; Chronic Disease; Cromolyn Sodium; Cyproheptadine; Dermat

2007
Fexofenadine: new preparation. Terfenadine, without cardiotoxicity.
    Prescrire international, 1999, Volume: 8, Issue:39

    Topics: Cetirizine; Chronic Disease; Clinical Trials as Topic; Drug Evaluation; Histamine Antagonists; Human

1999
Fexofenadine: a review of its use in the management of seasonal allergic rhinitis and chronic idiopathic urticaria.
    Drugs, 2000, Volume: 59, Issue:2

    Topics: Administration, Oral; Adolescent; Adult; Anti-Allergic Agents; Chronic Disease; Dose-Response Relati

2000
Terfenadine in allergic chronic cough in children.
    Allergy, 1992, Volume: 47, Issue:1

    Topics: Asthma; Child; Chronic Disease; Cough; Female; Humans; Hypersensitivity; Male; Pilot Projects; Terfe

1992
Antihistamines in the treatment of urticarial disorders.
    Cutis, 1988, Oct-27, Volume: 42, Issue:4A

    Topics: Astemizole; Benzhydryl Compounds; Benzimidazoles; Chronic Disease; Histamine H1 Antagonists; Humans;

1988
[Dermatographic urticaria: evaluation of the therapeutic efficacy of drugs using a dermatographic tester].
    Giornale italiano di dermatologia e venereologia : organo ufficiale, Societa italiana di dermatologia e sifilografia, 1987, Volume: 122, Issue:12

    Topics: Adolescent; Adult; Benzhydryl Compounds; Chronic Disease; Cinnarizine; Female; Humans; Hydroxyzine;

1987