terfenadine has been researched along with Cardiac Arrest, Sudden in 5 studies
Terfenadine: A selective histamine H1-receptor antagonist devoid of central nervous system depressant activity. The drug was used for ALLERGY but withdrawn due to causing LONG QT SYNDROME.
| Excerpt | Relevance | Reference |
|---|---|---|
| "This study compared the occurrence of syncope, ventricular arrhythmias, and corrected QT interval (QTc) prolongation over a 2 1/2-year period in persons prescribed terfenadine versus other prescription antihistamines among 265,000 members of the Harvard Community Health Plan (HCHP), the largest staff-model health maintenance organization in New England." | 7.69 | Terfenadine-associated ventricular arrhythmias and QTc interval prolongation. A retrospective cohort comparison with other antihistamines among members of a health maintenance organization. ( Carlson, W; Choo, PW; Faich, GA; Greineder, D; Hanrahan, JP; Platt, R, 1995) |
| "An observational, historical cohort evaluation was performed to examine the hypothesis that terfenadine (Seldane) exposure increases the risk of developing life-threatening ventricular arrhythmias." | 7.69 | Risk of developing life-threatening ventricular arrhythmia associated with tefenadine in comparison with over-the-counter antihistamines, ibuprofen and clemastine. ( Crowell, SP; Ellis, BE; Hertz, RP; Louv, W; Moyé, L; Pratt, CM, 1994) |
| "This study compared the occurrence of syncope, ventricular arrhythmias, and corrected QT interval (QTc) prolongation over a 2 1/2-year period in persons prescribed terfenadine versus other prescription antihistamines among 265,000 members of the Harvard Community Health Plan (HCHP), the largest staff-model health maintenance organization in New England." | 3.69 | Terfenadine-associated ventricular arrhythmias and QTc interval prolongation. A retrospective cohort comparison with other antihistamines among members of a health maintenance organization. ( Carlson, W; Choo, PW; Faich, GA; Greineder, D; Hanrahan, JP; Platt, R, 1995) |
| "An observational, historical cohort evaluation was performed to examine the hypothesis that terfenadine (Seldane) exposure increases the risk of developing life-threatening ventricular arrhythmias." | 3.69 | Risk of developing life-threatening ventricular arrhythmia associated with tefenadine in comparison with over-the-counter antihistamines, ibuprofen and clemastine. ( Crowell, SP; Ellis, BE; Hertz, RP; Louv, W; Moyé, L; Pratt, CM, 1994) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (60.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 1 (20.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Radnic, B | 1 |
| Radojevic, N | 1 |
| Vucinic, J | 1 |
| Duborija-Kovacevic, N | 1 |
| Brown, AM | 1 |
| Hanrahan, JP | 1 |
| Choo, PW | 1 |
| Carlson, W | 1 |
| Greineder, D | 1 |
| Faich, GA | 1 |
| Platt, R | 1 |
| Pratt, CM | 1 |
| Hertz, RP | 1 |
| Ellis, BE | 1 |
| Crowell, SP | 1 |
| Louv, W | 1 |
| Moyé, L | 1 |
| Flockhart, DA | 1 |
1 review available for terfenadine and Cardiac Arrest, Sudden
| Article | Year |
|---|---|
Drugs, hERG and sudden death.
Topics: Death, Sudden, Cardiac; Drug Evaluation, Preclinical; ERG1 Potassium Channel; Ether-A-Go-Go Potassiu | 2004 |
4 other studies available for terfenadine and Cardiac Arrest, Sudden
| Article | Year |
|---|---|
The association between pro-arrhythmic agents and aortic stenosis in young adults: is it sufficient to clarify the sudden unexpected deaths?
Topics: Adult; Amitriptyline; Aortic Valve Stenosis; Arrhythmias, Cardiac; Autopsy; Caffeine; Death, Sudden, | 2017 |
Terfenadine-associated ventricular arrhythmias and QTc interval prolongation. A retrospective cohort comparison with other antihistamines among members of a health maintenance organization.
Topics: Administration, Oral; Adolescent; Adult; Aged; Arrhythmias, Cardiac; Boston; Cohort Studies; Death, | 1995 |
Risk of developing life-threatening ventricular arrhythmia associated with tefenadine in comparison with over-the-counter antihistamines, ibuprofen and clemastine.
Topics: Adult; Age Factors; Aged; Arrhythmias, Cardiac; Clemastine; Cohort Studies; Death, Sudden, Cardiac; | 1994 |
Drug interactions, cardiac toxicity, and terfenadine: from bench to clinic?
Topics: Death, Sudden, Cardiac; Drug Interactions; Heart; Histamine H1 Antagonists; Humans; Long QT Syndrome | 1996 |