terfenadine has been researched along with Carcinoma, Hepatocellular in 3 studies
Terfenadine: A selective histamine H1-receptor antagonist devoid of central nervous system depressant activity. The drug was used for ALLERGY but withdrawn due to causing LONG QT SYNDROME.
Carcinoma, Hepatocellular: A primary malignant neoplasm of epithelial liver cells. It ranges from a well-differentiated tumor with EPITHELIAL CELLS indistinguishable from normal HEPATOCYTES to a poorly differentiated neoplasm. The cells may be uniform or markedly pleomorphic, or form GIANT CELLS. Several classification schemes have been suggested.
| Excerpt | Relevance | Reference |
|---|---|---|
| " In this study we analyzed the effects of both histamine and pre-formed mediators spontaneously released by mast cells on the growth of two human hepatocellular carcinoma cell lines, HA22T/VGH and HuH-6, with different characteristics of differentiation, biological behavior and genetic defects." | 7.74 | Histamine and spontaneously released mast cell granules affect the cell growth of human hepatocellular carcinoma cells. ( Azzolina, A; Cervello, M; Lampiasi, N; Montalto, G, 2007) |
| "A 65-year-old woman with liver cirrhosis complicated by hepatocellular carcinoma lost consciousness due to torsades de pointes with prolongation of the QT-interval after 10 days of treatment with terfenadine." | 7.69 | Torsades de pointes associated with terfenadine in a case of liver cirrhosis and hepatocellular carcinoma. ( Adachi, Y; Kamisako, T; Nakagawa, H; Yamamoto, T, 1995) |
| " In this study we analyzed the effects of both histamine and pre-formed mediators spontaneously released by mast cells on the growth of two human hepatocellular carcinoma cell lines, HA22T/VGH and HuH-6, with different characteristics of differentiation, biological behavior and genetic defects." | 3.74 | Histamine and spontaneously released mast cell granules affect the cell growth of human hepatocellular carcinoma cells. ( Azzolina, A; Cervello, M; Lampiasi, N; Montalto, G, 2007) |
| "A 65-year-old woman with liver cirrhosis complicated by hepatocellular carcinoma lost consciousness due to torsades de pointes with prolongation of the QT-interval after 10 days of treatment with terfenadine." | 3.69 | Torsades de pointes associated with terfenadine in a case of liver cirrhosis and hepatocellular carcinoma. ( Adachi, Y; Kamisako, T; Nakagawa, H; Yamamoto, T, 1995) |
| "Ketoconazole (KT) is a worldwide used oral antifungal agent with a broad spectrum of activity against both superficial and systemic mycosis." | 1.31 | Ketoconazole potentiates terfenadine-induced apoptosis in human Hep G2 cells through inhibition of cytochrome p450 3A4 activity. ( Chen, CF; Chen, CH; Chen, LC; Ho, YS; Liang, YC; Lin, CH; Lin, JK; Lin, SY; Wang, YJ; Yu, CF, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 2 (66.67) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wang, YJ | 1 |
| Yu, CF | 1 |
| Chen, LC | 1 |
| Chen, CH | 1 |
| Lin, JK | 1 |
| Liang, YC | 1 |
| Lin, CH | 1 |
| Lin, SY | 1 |
| Chen, CF | 1 |
| Ho, YS | 1 |
| Lampiasi, N | 1 |
| Azzolina, A | 1 |
| Montalto, G | 1 |
| Cervello, M | 1 |
| Kamisako, T | 1 |
| Adachi, Y | 1 |
| Nakagawa, H | 1 |
| Yamamoto, T | 1 |
3 other studies available for terfenadine and Carcinoma, Hepatocellular
| Article | Year |
|---|---|
Ketoconazole potentiates terfenadine-induced apoptosis in human Hep G2 cells through inhibition of cytochrome p450 3A4 activity.
Topics: Animals; Apoptosis; Baculoviridae; Carcinoma, Hepatocellular; Cytochrome P-450 CYP3A; Cytochrome P-4 | 2002 |
Histamine and spontaneously released mast cell granules affect the cell growth of human hepatocellular carcinoma cells.
Topics: Animals; Apoptosis; beta Catenin; Carcinoma, Hepatocellular; Caspase 3; Cell Line, Tumor; Cell Proli | 2007 |
Torsades de pointes associated with terfenadine in a case of liver cirrhosis and hepatocellular carcinoma.
Topics: Aged; Carcinoma, Hepatocellular; Electrocardiography; Female; Humans; Liver Cirrhosis; Liver Neoplas | 1995 |