terfenadine has been researched along with Cancer of Prostate in 5 studies
Terfenadine: A selective histamine H1-receptor antagonist devoid of central nervous system depressant activity. The drug was used for ALLERGY but withdrawn due to causing LONG QT SYNDROME.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Enzalutamide also induced bradycardia and death in zebrafish embryos in a dose-dependent manner and strongly synergized with the potassium-channel blocking agent, terfenadine, known to induce long QT syndrome and cardiac arrhythmia." | 3.85 | Enzalutamide inhibits testosterone-induced growth of human prostate cancer xenografts in zebrafish and can induce bradycardia. ( Berman, JN; Collins, CC; Dellaire, G; Holly, A; MacDonald, M; Melong, N; Steele, S; Zoubeidi, A, 2017) |
| "Salinomycin inhibited the growth of prostate cancer cells, but did not affect non-malignant prostate epithelial cells." | 1.38 | Salinomycin inhibits prostate cancer growth and migration via induction of oxidative stress. ( Hilvo, M; Hyötyläinen, T; Iljin, K; Kallioniemi, O; Ketola, K; Orešič, M; Ruskeepää, AL; Vuoristo, A, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 5 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wlodarczyk, N | 1 |
| Le Broc-Ryckewaert, D | 1 |
| Gilleron, P | 1 |
| Lemoine, A | 1 |
| Farce, A | 1 |
| Chavatte, P | 1 |
| Dubois, J | 1 |
| Pommery, N | 1 |
| Hénichart, JP | 1 |
| Furman, C | 1 |
| Millet, R | 1 |
| Melong, N | 1 |
| Steele, S | 1 |
| MacDonald, M | 1 |
| Holly, A | 1 |
| Collins, CC | 1 |
| Zoubeidi, A | 1 |
| Berman, JN | 1 |
| Dellaire, G | 1 |
| Wang, WT | 1 |
| Chen, YH | 1 |
| Hsu, JL | 1 |
| Leu, WJ | 1 |
| Yu, CC | 1 |
| Chan, SH | 1 |
| Ho, YF | 1 |
| Hsu, LC | 1 |
| Guh, JH | 1 |
| Ketola, K | 2 |
| Vainio, P | 1 |
| Fey, V | 1 |
| Kallioniemi, O | 2 |
| Iljin, K | 2 |
| Hilvo, M | 1 |
| Hyötyläinen, T | 1 |
| Vuoristo, A | 1 |
| Ruskeepää, AL | 1 |
| Orešič, M | 1 |
5 other studies available for terfenadine and Cancer of Prostate
| Article | Year |
|---|---|
Potent farnesyltransferase inhibitors with 1,4-diazepane scaffolds as novel destabilizing microtubule agents in hormone-resistant prostate cancer.
Topics: Androgen Antagonists; Azepines; Cell Line; Cell Line, Tumor; Drug Resistance, Neoplasm; Drug Screeni | 2011 |
Enzalutamide inhibits testosterone-induced growth of human prostate cancer xenografts in zebrafish and can induce bradycardia.
Topics: Animals; Antineoplastic Agents; Benzamides; Bradycardia; Cell Line, Tumor; Cell Proliferation; Disea | 2017 |
Terfenadine induces anti-proliferative and apoptotic activities in human hormone-refractory prostate cancer through histamine receptor-independent Mcl-1 cleavage and Bak up-regulation.
Topics: Apoptosis; bcl-2 Homologous Antagonist-Killer Protein; Cell Proliferation; Dose-Response Relationshi | 2014 |
Monensin is a potent inducer of oxidative stress and inhibitor of androgen signaling leading to apoptosis in prostate cancer cells.
Topics: Aldehyde Dehydrogenase; Androgen Antagonists; Androgens; Animals; Apoptosis; Ascorbic Acid; Cattle; | 2010 |
Salinomycin inhibits prostate cancer growth and migration via induction of oxidative stress.
Topics: Aldehyde Dehydrogenase; Blotting, Western; Cell Division; Cell Line, Tumor; Cell Movement; Humans; M | 2012 |