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terfenadine and Bronchospasm, Exercise-Induced

terfenadine has been researched along with Bronchospasm, Exercise-Induced in 9 studies

Terfenadine: A selective histamine H1-receptor antagonist devoid of central nervous system depressant activity. The drug was used for ALLERGY but withdrawn due to causing LONG QT SYNDROME.

Research Excerpts

ExcerptRelevanceReference
"The effect of terfenadine, a selective H1-receptor antagonist devoid of central nervous system side effects, was evaluated on hyperventilation-induced bronchospasm in 11 adult subjects with asthma in a double-blind, placebo-controlled, crossover study."9.06Attenuation of hyperventilation-induced bronchospasm by terfenadine: a new antihistamine. ( Badier, M; Beaumont, D; Orehek, J, 1988)
"The orally active histamine H1 blocker terfenadine was investigated for its effect on resting bronchial tone and exercise induced bronchoconstriction in 20 asthmatic children by a double blind placebo controlled study."9.06Selective histamine blockade in childhood asthma; the effect of terfenadine on resting bronchial tone and exercise induced bronchoconstriction. ( Heaf, DP; MacFarlane, PI, 1989)
"To assess the role of histamine as a mediator in the response to exercise and isocapnic hyperventilation of cold air (IHCA) in asthma, we studied nine asthmatic subjects, age 13 to 25 years."7.67Effect of terfenadine on the response to exercise and cold air in asthma. ( Chernick, V; Montgomery, M; Pasterkamp, H; Poynter, A; Wiebicke, W, 1988)
"Terfenadine or placebo was administered 3 h prior to exercise, and flurbiprofen or placebo was administered 2 h prior to exercise, in a double-blind randomized trial."6.67Evidence for the roles of histamine and prostaglandins as mediators in exercise-induced asthma: the inhibitory effect of terfenadine and flurbiprofen alone and in combination. ( Finnerty, JP; Holgate, ST, 1990)
"The effect of terfenadine, a selective H1-receptor antagonist devoid of central nervous system side effects, was evaluated on hyperventilation-induced bronchospasm in 11 adult subjects with asthma in a double-blind, placebo-controlled, crossover study."5.06Attenuation of hyperventilation-induced bronchospasm by terfenadine: a new antihistamine. ( Badier, M; Beaumont, D; Orehek, J, 1988)
"The orally active histamine H1 blocker terfenadine was investigated for its effect on resting bronchial tone and exercise induced bronchoconstriction in 20 asthmatic children by a double blind placebo controlled study."5.06Selective histamine blockade in childhood asthma; the effect of terfenadine on resting bronchial tone and exercise induced bronchoconstriction. ( Heaf, DP; MacFarlane, PI, 1989)
"To assess the role of histamine as a mediator in the response to exercise and isocapnic hyperventilation of cold air (IHCA) in asthma, we studied nine asthmatic subjects, age 13 to 25 years."3.67Effect of terfenadine on the response to exercise and cold air in asthma. ( Chernick, V; Montgomery, M; Pasterkamp, H; Poynter, A; Wiebicke, W, 1988)
"Terfenadine or placebo was administered 3 h prior to exercise, and flurbiprofen or placebo was administered 2 h prior to exercise, in a double-blind randomized trial."2.67Evidence for the roles of histamine and prostaglandins as mediators in exercise-induced asthma: the inhibitory effect of terfenadine and flurbiprofen alone and in combination. ( Finnerty, JP; Holgate, ST, 1990)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19905 (55.56)18.7374
1990's3 (33.33)18.2507
2000's0 (0.00)29.6817
2010's1 (11.11)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Magen, E1
Chikovani, T1
Patel, KR1
Finnerty, JP2
Holgate, ST2
Anderson, SD1
Badier, M1
Beaumont, D1
Orehek, J1
MacFarlane, PI1
Heaf, DP1
Wiebicke, W1
Poynter, A1
Montgomery, M1
Chernick, V1
Pasterkamp, H1
MacFarlane, P1
Heaf, D1

Trials

5 trials available for terfenadine and Bronchospasm, Exercise-Induced

ArticleYear
Terfenadine in exercise induced asthma.
    British medical journal (Clinical research ed.), 1984, May-19, Volume: 288, Issue:6429

    Topics: Adolescent; Adult; Asthma; Asthma, Exercise-Induced; Benzhydryl Compounds; Clinical Trials as Topic;

1984
The contribution of histamine release and vagal reflexes, alone and in combination, to exercise-induced asthma.
    The European respiratory journal, 1993, Volume: 6, Issue:8

    Topics: Adult; Asthma, Exercise-Induced; Double-Blind Method; Exercise Test; Female; Forced Expiratory Volum

1993
Evidence for the roles of histamine and prostaglandins as mediators in exercise-induced asthma: the inhibitory effect of terfenadine and flurbiprofen alone and in combination.
    The European respiratory journal, 1990, Volume: 3, Issue:5

    Topics: Adult; Asthma; Asthma, Exercise-Induced; Benzhydryl Compounds; Double-Blind Method; Exercise Test; F

1990
Attenuation of hyperventilation-induced bronchospasm by terfenadine: a new antihistamine.
    The Journal of allergy and clinical immunology, 1988, Volume: 81, Issue:2

    Topics: Adolescent; Adult; Asthma, Exercise-Induced; Benzhydryl Compounds; Bronchial Spasm; Clinical Trials

1988
Selective histamine blockade in childhood asthma; the effect of terfenadine on resting bronchial tone and exercise induced bronchoconstriction.
    Respiratory medicine, 1989, Volume: 83, Issue:1

    Topics: Adolescent; Airway Resistance; Asthma; Asthma, Exercise-Induced; Benzhydryl Compounds; Bronchi; Chil

1989

Other Studies

4 other studies available for terfenadine and Bronchospasm, Exercise-Induced

ArticleYear
A case of food-dependent exercise-induced angioedema.
    The journal of allergy and clinical immunology. In practice, 2019, Volume: 7, Issue:1

    Topics: Adult; Allergens; Angioedema; Animals; Asthma, Exercise-Induced; Cattle; Diet Therapy; Female; Human

2019
Drugs and the control of exercise-induced asthma.
    The European respiratory journal, 1993, Volume: 6, Issue:8

    Topics: Adult; Aerosols; Asthma, Exercise-Induced; Bronchodilator Agents; Child; Cromolyn Sodium; Dose-Respo

1993
Effect of terfenadine on the response to exercise and cold air in asthma.
    Pediatric pulmonology, 1988, Volume: 4, Issue:4

    Topics: Adolescent; Adult; Asthma; Asthma, Exercise-Induced; Benzhydryl Compounds; Cold Temperature; Forced

1988
Pre-treatment with terfenadine.
    Pediatric pulmonology, 1988, Volume: 5, Issue:4

    Topics: Asthma; Asthma, Exercise-Induced; Benzhydryl Compounds; Child; Humans; Terfenadine

1988