terfenadine has been researched along with Bronchial Hyperreactivity in 12 studies
Terfenadine: A selective histamine H1-receptor antagonist devoid of central nervous system depressant activity. The drug was used for ALLERGY but withdrawn due to causing LONG QT SYNDROME.
Bronchial Hyperreactivity: Tendency of the smooth muscle of the tracheobronchial tree to contract more intensely in response to a given stimulus than it does in the response seen in normal individuals. This condition is present in virtually all symptomatic patients with asthma. The most prominent manifestation of this smooth muscle contraction is a decrease in airway caliber that can be readily measured in the pulmonary function laboratory.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Acetaldehyde induces bronchial hyperresponsiveness in patients with asthma by mechanisms other than histamine release." | 9.07 | Potentiating effect of inhaled acetaldehyde on bronchial responsiveness to methacholine in asthmatic subjects. ( Fujimura, M; Matsuda, M; Matsuda, T; Myou, S; Nishi, K; Ohka, T, 1994) |
| "Fexofenadine treatment of sensitized mice prevented the development of airway hyperresponsiveness in both the primary sensitization and challenge, as well as in the adoptive transfer experiments." | 5.31 | Fexofenadine modulates T-cell function, preventing allergen-induced airway inflammation and hyperresponsiveness. ( Cui, ZH; Gelfand, EW; Joetham, A; Kanehiro, A; Takeda, K, 2002) |
| "The goal of the study was to determine if pranlukast has effects on the upper and lower airways through a comparison of the effects of fexofenadine and pranlukast on airway hyperresponsiveness in non-asthmatic patients with cedar pollinosis before the Japanese cedar pollen season and during the peak pollen season." | 5.14 | Effects of pranlukast hydrate on airway hyperresponsiveness in non-asthmatic patients with Japanese cedar pollinosis. ( Fukuda, T; Kashima, R; Okada, T; Sagara, H; Yukawa, T, 2009) |
| "We studied, separately, the effects of the histamine antagonist, fexofenadine hydrochloride, and the leukotriene antagonist, montelukast sodium, and their placebos on airway sensitivity to and recovery from inhaled mannitol in subjects with asthma." | 5.09 | Fexofenadine decreases sensitivity to and montelukast improves recovery from inhaled mannitol. ( Anderson, SD; Brannan, JD; Chan, HK; Gomes, K; King, GG; Seale, JP, 2001) |
| "Acetaldehyde induces bronchial hyperresponsiveness in patients with asthma by mechanisms other than histamine release." | 5.07 | Potentiating effect of inhaled acetaldehyde on bronchial responsiveness to methacholine in asthmatic subjects. ( Fujimura, M; Matsuda, M; Matsuda, T; Myou, S; Nishi, K; Ohka, T, 1994) |
| " Allergic bronchial eosinophilia in guinea pigs was inhibited by orally administered dexamethasone and methylprednisolone." | 3.68 | Allergic bronchial eosinophilia: a therapeutic approach for the selection of potential bronchial anti-inflammatory drugs. ( Chand, N; De Vine, CL; Diamantis, W; Harrison, JE; Jakubicki, RG; Nolan, KW; Pillar, J; Rooney, SM; Sofia, RD, 1993) |
| "We measured the bronchial response to histamine in 26 allergic asthmatics and 17 healthy subjects before and after the bronchial pretreatment with selective H2-receptor antagonist ranitidine." | 3.68 | [A study on the relationship between histamine receptors and bronchial hyperresponsiveness in asthma]. ( Wang, SZ, 1991) |
| "Fexofenadine treatment of sensitized mice prevented the development of airway hyperresponsiveness in both the primary sensitization and challenge, as well as in the adoptive transfer experiments." | 1.31 | Fexofenadine modulates T-cell function, preventing allergen-induced airway inflammation and hyperresponsiveness. ( Cui, ZH; Gelfand, EW; Joetham, A; Kanehiro, A; Takeda, K, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 6 (50.00) | 18.2507 |
| 2000's | 6 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Sagara, H | 1 |
| Yukawa, T | 1 |
| Kashima, R | 1 |
| Okada, T | 1 |
| Fukuda, T | 1 |
| Gelfand, EW | 1 |
| Cui, ZH | 1 |
| Takeda, K | 1 |
| Kanehiro, A | 1 |
| Joetham, A | 1 |
| Kamei, J | 1 |
| Takahashi, Y | 2 |
| Itabashi, T | 1 |
| Hayashi, S | 1 |
| Kawai, K | 1 |
| Myou, S | 2 |
| Fujimura, M | 2 |
| Nishi, K | 1 |
| Matsuda, M | 1 |
| Ohka, T | 1 |
| Matsuda, T | 2 |
| Chand, N | 1 |
| Harrison, JE | 1 |
| Rooney, SM | 1 |
| Nolan, KW | 1 |
| De Vine, CL | 1 |
| Jakubicki, RG | 1 |
| Pillar, J | 1 |
| Diamantis, W | 1 |
| Sofia, RD | 1 |
| Nomura, M | 1 |
| Harada, A | 1 |
| Mukaida, N | 1 |
| Matsushima, K | 1 |
| Nonomura, A | 1 |
| Rutgers, SR | 1 |
| Koëter, GH | 1 |
| van der Mark, TW | 1 |
| Postma, DS | 1 |
| Musoh, K | 1 |
| Maeda, Y | 1 |
| Tanaka, H | 2 |
| Inagaki, N | 2 |
| Nagai, H | 2 |
| Kawada, N | 1 |
| Takizawa, T | 1 |
| Yamada, T | 1 |
| Masuda, T | 1 |
| Brannan, JD | 1 |
| Anderson, SD | 1 |
| Gomes, K | 1 |
| King, GG | 1 |
| Chan, HK | 1 |
| Seale, JP | 1 |
| Umut, S | 1 |
| Koldaş, L | 1 |
| Gürsoy, M | 1 |
| Gemicioğlu, B | 1 |
| Yildirim, N | 1 |
| Barlas, A | 1 |
| Ozüner, Z | 1 |
| Wang, SZ | 1 |
4 trials available for terfenadine and Bronchial Hyperreactivity
| Article | Year |
|---|---|
Effects of pranlukast hydrate on airway hyperresponsiveness in non-asthmatic patients with Japanese cedar pollinosis.
Topics: Acetylcholine; Activities of Daily Living; Adult; Anti-Allergic Agents; Anti-Asthmatic Agents; Antig | 2009 |
Potentiating effect of inhaled acetaldehyde on bronchial responsiveness to methacholine in asthmatic subjects.
Topics: Acetaldehyde; Adult; Aged; Asthma; Bronchi; Bronchial Hyperreactivity; Bronchial Provocation Tests; | 1994 |
Short-term treatment with budesonide does not improve hyperresponsiveness to adenosine 5'-monophosphate in COPD.
Topics: Adenosine Monophosphate; Administration, Inhalation; Anti-Inflammatory Agents; Bronchial Hyperreacti | 1998 |
Fexofenadine decreases sensitivity to and montelukast improves recovery from inhaled mannitol.
Topics: Acetates; Administration, Inhalation; Adolescent; Adult; Aged; Anti-Asthmatic Agents; Asthma; Bronch | 2001 |
8 other studies available for terfenadine and Bronchial Hyperreactivity
| Article | Year |
|---|---|
Fexofenadine modulates T-cell function, preventing allergen-induced airway inflammation and hyperresponsiveness.
Topics: Adoptive Transfer; Allergens; Animals; Anti-Allergic Agents; Bronchial Hyperreactivity; Bronchoalveo | 2002 |
Atopic cough-like cough hypersensitivity caused by active sensitization with protein fraction of Aspergillus restrictus strain A-17.
Topics: Administration, Inhalation; Animals; Antigens, Fungal; Antitussive Agents; Aspergillus; Bronchial Hy | 2008 |
Allergic bronchial eosinophilia: a therapeutic approach for the selection of potential bronchial anti-inflammatory drugs.
Topics: Albuterol; Allergens; Animals; Anti-Inflammatory Agents; Asthma; Bronchial Hyperreactivity; Bronchoa | 1993 |
Effect of thromboxane A2 antagonists on bronchial hyperresponsiveness induced immediately after interleukin-8 inhalation in guinea-pigs.
Topics: Administration, Inhalation; Animals; Bridged Bicyclo Compounds; Bronchial Hyperreactivity; Fatty Aci | 1997 |
Effect of a novel anti-allergic agent, HSR-609, on antigen-induced airway hyperresponsiveness in mice.
Topics: Acetylcholine; Animals; Anti-Allergic Agents; Anti-Inflammatory Agents; Benzoxepins; Bronchial Hyper | 2000 |
Role of mast cells in antigen-induced airway inflammation and bronchial hyperresponsiveness in rats.
Topics: Acetylcholine; Animals; Anti-Inflammatory Agents; Bronchial Hyperreactivity; Bronchoalveolar Lavage | 2001 |
Venous blood histamine levels and effect of terfenadine in patients with bronchial hyperreactivity.
Topics: Adult; Bronchial Hyperreactivity; Bronchial Provocation Tests; Female; Forced Expiratory Volume; His | 1992 |
[A study on the relationship between histamine receptors and bronchial hyperresponsiveness in asthma].
Topics: Adolescent; Adult; Asthma; Bronchial Hyperreactivity; Female; Humans; Male; Ranitidine; Receptors, H | 1991 |