terfenadine has been researched along with Bradyarrhythmia in 4 studies
Terfenadine: A selective histamine H1-receptor antagonist devoid of central nervous system depressant activity. The drug was used for ALLERGY but withdrawn due to causing LONG QT SYNDROME.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Enzalutamide also induced bradycardia and death in zebrafish embryos in a dose-dependent manner and strongly synergized with the potassium-channel blocking agent, terfenadine, known to induce long QT syndrome and cardiac arrhythmia." | 3.85 | Enzalutamide inhibits testosterone-induced growth of human prostate cancer xenografts in zebrafish and can induce bradycardia. ( Berman, JN; Collins, CC; Dellaire, G; Holly, A; MacDonald, M; Melong, N; Steele, S; Zoubeidi, A, 2017) |
| "The effects of epinastine hydrochloride and terfenadine on electrocardiographic (ECG) parameters in rats were investigated from a pharmacokinetic and pharmacodynamic perspective." | 1.30 | A comparative pharmacokinetic-pharmacodynamic study of the electrocardiographic effects of epinastine and terfenadine in rats. ( Iga, T; Kotaki, H; Ohtani, H; Sawada, Y, 1997) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (50.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Melong, N | 1 |
| Steele, S | 1 |
| MacDonald, M | 1 |
| Holly, A | 1 |
| Collins, CC | 1 |
| Zoubeidi, A | 1 |
| Berman, JN | 1 |
| Dellaire, G | 1 |
| Takahara, A | 1 |
| Sugiyama, A | 1 |
| Ishida, Y | 1 |
| Satoh, Y | 1 |
| Wang, K | 1 |
| Nakamura, Y | 1 |
| Hashimoto, K | 1 |
| Crane, JK | 1 |
| Shih, HT | 1 |
| Ohtani, H | 1 |
| Kotaki, H | 1 |
| Sawada, Y | 1 |
| Iga, T | 1 |
4 other studies available for terfenadine and Bradyarrhythmia
| Article | Year |
|---|---|
Enzalutamide inhibits testosterone-induced growth of human prostate cancer xenografts in zebrafish and can induce bradycardia.
Topics: Animals; Antineoplastic Agents; Benzamides; Bradycardia; Cell Line, Tumor; Cell Proliferation; Disea | 2017 |
Long-term bradycardia caused by atrioventricular block can remodel the canine heart to detect the histamine H1 blocker terfenadine-induced torsades de pointes arrhythmias.
Topics: Animals; Atrioventricular Node; Bradycardia; Catheter Ablation; Dogs; Dose-Response Relationship, Dr | 2006 |
Syncope and cardiac arrhythmia due to an interaction between itraconazole and terfenadine.
Topics: Bradycardia; Drug Interactions; Humans; Itraconazole; Male; Middle Aged; Syncope; Terfenadine | 1993 |
A comparative pharmacokinetic-pharmacodynamic study of the electrocardiographic effects of epinastine and terfenadine in rats.
Topics: Animals; Bradycardia; Chromatography, High Pressure Liquid; Dibenzazepines; Dose-Response Relationsh | 1997 |