terfenadine has been researched along with Benign Neoplasms in 6 studies
Terfenadine: A selective histamine H1-receptor antagonist devoid of central nervous system depressant activity. The drug was used for ALLERGY but withdrawn due to causing LONG QT SYNDROME.
Excerpt | Relevance | Reference |
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" In addition, characterization of the UGT1A locus and genetic studies directed at understanding the role of bilirubin glucuronidation and the biochemical basis of the clinical symptoms found in unconjugated hyperbilirubinemia have uncovered the structural gene polymorphisms associated with Crigler-Najjar's and Gilbert's syndrome." | 4.80 | Human UDP-glucuronosyltransferases: metabolism, expression, and disease. ( Strassburg, CP; Tukey, RH, 2000) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 3 (50.00) | 29.6817 |
2010's | 3 (50.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Tukey, RH | 1 |
Strassburg, CP | 1 |
Diamandis, P | 1 |
Wildenhain, J | 1 |
Clarke, ID | 1 |
Sacher, AG | 1 |
Graham, J | 1 |
Bellows, DS | 1 |
Ling, EK | 1 |
Ward, RJ | 1 |
Jamieson, LG | 1 |
Tyers, M | 1 |
Dirks, PB | 1 |
Unzue, A | 1 |
Lafleur, K | 1 |
Zhao, H | 1 |
Zhou, T | 1 |
Dong, J | 1 |
Kolb, P | 1 |
Liebl, J | 1 |
Zahler, S | 1 |
Caflisch, A | 1 |
Nevado, C | 1 |
Chen, C | 2 |
Wang, DW | 2 |
Li, G | 1 |
Liao, W | 1 |
Wu, J | 1 |
Liu, L | 1 |
Ma, D | 1 |
Zhou, J | 1 |
Elbekai, RH | 1 |
Edin, ML | 1 |
Zeldin, DC | 1 |
Covell, DG | 1 |
3 reviews available for terfenadine and Benign Neoplasms
Article | Year |
---|---|
Human UDP-glucuronosyltransferases: metabolism, expression, and disease.
Topics: Autoimmunity; Chromosome Mapping; Glucuronides; Glucuronosyltransferase; Humans; Hyperbilirubinemia; | 2000 |
Three stories on Eph kinase inhibitors: From in silico discovery to in vivo validation.
Topics: Animals; Computer Simulation; Drug Design; Humans; Isoquinolines; Neoplasms; Protein Kinase Inhibito | 2016 |
CYP epoxygenase derived EETs: from cardiovascular protection to human cancer therapy.
Topics: 8,11,14-Eicosatrienoic Acid; Cardiovascular Diseases; Cytochrome P-450 CYP2J2; Cytochrome P-450 Enzy | 2013 |
3 other studies available for terfenadine and Benign Neoplasms
Article | Year |
---|---|
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutic | 2007 |
Selective inhibitors of CYP2J2 related to terfenadine exhibit strong activity against human cancers in vitro and in vivo.
Topics: Animals; Antineoplastic Agents; Apoptosis; Caspase 3; Cell Adhesion; Cell Line, Tumor; Cell Movement | 2009 |
Integrating constitutive gene expression and chemoactivity: mining the NCI60 anticancer screen.
Topics: Algorithms; Antineoplastic Agents; Camptothecin; Cell Line, Tumor; Cell Proliferation; Cell Survival | 2012 |