Page last updated: 2024-11-04

terfenadine and Benign Neoplasms

terfenadine has been researched along with Benign Neoplasms in 6 studies

Terfenadine: A selective histamine H1-receptor antagonist devoid of central nervous system depressant activity. The drug was used for ALLERGY but withdrawn due to causing LONG QT SYNDROME.

Research Excerpts

ExcerptRelevanceReference
" In addition, characterization of the UGT1A locus and genetic studies directed at understanding the role of bilirubin glucuronidation and the biochemical basis of the clinical symptoms found in unconjugated hyperbilirubinemia have uncovered the structural gene polymorphisms associated with Crigler-Najjar's and Gilbert's syndrome."4.80Human UDP-glucuronosyltransferases: metabolism, expression, and disease. ( Strassburg, CP; Tukey, RH, 2000)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (50.00)29.6817
2010's3 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Tukey, RH1
Strassburg, CP1
Diamandis, P1
Wildenhain, J1
Clarke, ID1
Sacher, AG1
Graham, J1
Bellows, DS1
Ling, EK1
Ward, RJ1
Jamieson, LG1
Tyers, M1
Dirks, PB1
Unzue, A1
Lafleur, K1
Zhao, H1
Zhou, T1
Dong, J1
Kolb, P1
Liebl, J1
Zahler, S1
Caflisch, A1
Nevado, C1
Chen, C2
Wang, DW2
Li, G1
Liao, W1
Wu, J1
Liu, L1
Ma, D1
Zhou, J1
Elbekai, RH1
Edin, ML1
Zeldin, DC1
Covell, DG1

Reviews

3 reviews available for terfenadine and Benign Neoplasms

ArticleYear
Human UDP-glucuronosyltransferases: metabolism, expression, and disease.
    Annual review of pharmacology and toxicology, 2000, Volume: 40

    Topics: Autoimmunity; Chromosome Mapping; Glucuronides; Glucuronosyltransferase; Humans; Hyperbilirubinemia;

2000
Three stories on Eph kinase inhibitors: From in silico discovery to in vivo validation.
    European journal of medicinal chemistry, 2016, Apr-13, Volume: 112

    Topics: Animals; Computer Simulation; Drug Design; Humans; Isoquinolines; Neoplasms; Protein Kinase Inhibito

2016
CYP epoxygenase derived EETs: from cardiovascular protection to human cancer therapy.
    Current topics in medicinal chemistry, 2013, Volume: 13, Issue:12

    Topics: 8,11,14-Eicosatrienoic Acid; Cardiovascular Diseases; Cytochrome P-450 CYP2J2; Cytochrome P-450 Enzy

2013

Other Studies

3 other studies available for terfenadine and Benign Neoplasms

ArticleYear
Chemical genetics reveals a complex functional ground state of neural stem cells.
    Nature chemical biology, 2007, Volume: 3, Issue:5

    Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutic

2007
Selective inhibitors of CYP2J2 related to terfenadine exhibit strong activity against human cancers in vitro and in vivo.
    The Journal of pharmacology and experimental therapeutics, 2009, Volume: 329, Issue:3

    Topics: Animals; Antineoplastic Agents; Apoptosis; Caspase 3; Cell Adhesion; Cell Line, Tumor; Cell Movement

2009
Integrating constitutive gene expression and chemoactivity: mining the NCI60 anticancer screen.
    PloS one, 2012, Volume: 7, Issue:10

    Topics: Algorithms; Antineoplastic Agents; Camptothecin; Cell Line, Tumor; Cell Proliferation; Cell Survival

2012