terfenadine has been researched along with Atrioventricular Nodal Re-Entrant Tachycardia in 10 studies
Terfenadine: A selective histamine H1-receptor antagonist devoid of central nervous system depressant activity. The drug was used for ALLERGY but withdrawn due to causing LONG QT SYNDROME.
| Excerpt | Relevance | Reference |
|---|---|---|
| "For terfenadine, TRIaD predicts drug-induced proarrhythmia: with λ prolongation, Torsade de Pointes is preferred, otherwise ventricular tachycardia/ventricular fibrillation." | 3.77 | Drug-induced QTC prolongation dangerously underestimates proarrhythmic potential: lessons from terfenadine. ( De Clerck, F; Dujardin, K; Dumotier, B; Hoffmann, P; Hondeghem, LM, 2011) |
| "Terfenadine is a second generation histamine receptor antagonist which is widely used as a non‑sedating antihistamine to relieve allergic responses." | 1.40 | Comparative study of the protective effects of terfenadine and amiodarone on barium chloride/aconitine-induced ventricular arrhythmias in rats: a potential role of terfenadine. ( Li, S; Liu, B; Su, Y; Xiong, M; Xu, Y, 2014) |
| "Terfenadine has been reported to cause cardiac death." | 1.38 | Does terfenadine-induced ventricular tachycardia/fibrillation directly relate to its QT prolongation and Torsades de Pointes? ( Gallacher, DJ; Hermans, AN; Lu, HR, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 6 (60.00) | 18.2507 |
| 2000's | 1 (10.00) | 29.6817 |
| 2010's | 3 (30.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Liu, B | 1 |
| Li, S | 1 |
| Su, Y | 1 |
| Xiong, M | 1 |
| Xu, Y | 1 |
| Hondeghem, LM | 1 |
| Dujardin, K | 1 |
| Hoffmann, P | 1 |
| Dumotier, B | 1 |
| De Clerck, F | 1 |
| Lu, HR | 1 |
| Hermans, AN | 1 |
| Gallacher, DJ | 1 |
| Aiba, T | 1 |
| Shimizu, W | 1 |
| Hidaka, I | 1 |
| Uemura, K | 1 |
| Noda, T | 1 |
| Zheng, C | 1 |
| Kamiya, A | 1 |
| Inagaki, M | 1 |
| Sugimachi, M | 1 |
| Sunagawa, K | 1 |
| Woosley, R | 1 |
| Darrow, WR | 1 |
| Kothari, SS | 1 |
| Sharma, S | 1 |
| Wasir, HS | 1 |
| DuBuske, LM | 1 |
| de Abajo, FJ | 1 |
| Rodríguez, LA | 1 |
| Pinto, YM | 1 |
| van Gelder, IC | 1 |
| Heeringa, M | 1 |
| Crijns, HJ | 1 |
1 review available for terfenadine and Atrioventricular Nodal Re-Entrant Tachycardia
| Article | Year |
|---|---|
Second-generation antihistamines: the risk of ventricular arrhythmias.
Topics: Animals; Astemizole; Cytochrome P-450 Enzyme System; Drug Interactions; Electrocardiography; Heart; | 1999 |
9 other studies available for terfenadine and Atrioventricular Nodal Re-Entrant Tachycardia
| Article | Year |
|---|---|
Comparative study of the protective effects of terfenadine and amiodarone on barium chloride/aconitine-induced ventricular arrhythmias in rats: a potential role of terfenadine.
Topics: Aconitine; Amiodarone; Animals; Anti-Arrhythmia Agents; Barium Compounds; Chlorides; Electrocardiogr | 2014 |
Drug-induced QTC prolongation dangerously underestimates proarrhythmic potential: lessons from terfenadine.
Topics: Action Potentials; Animals; Dose-Response Relationship, Drug; Electrocardiography; Female; Heart; Hi | 2011 |
Does terfenadine-induced ventricular tachycardia/fibrillation directly relate to its QT prolongation and Torsades de Pointes?
Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Atrial Appendage; Biological Transport; Cells, C | 2012 |
Cellular basis for trigger and maintenance of ventricular fibrillation in the Brugada syndrome model: high-resolution optical mapping study.
Topics: Action Potentials; Animals; Cardiovascular Agents; Disease Models, Animal; Dogs; Electrocardiography | 2006 |
Analysis of potential adverse drug reactions--a case of mistaken identity.
Topics: Astemizole; Atrial Fibrillation; Drug Interactions; Electrocardiography; Humans; Loratadine; Quinidi | 1994 |
Terfenadine overdose induced polymorphous ventricular tachycardia.
Topics: Child; Drug Overdose; Heart Septal Defects, Ventricular; Histamine H1 Antagonists; Humans; Male; Pos | 1995 |
FDA announces plan to halt marketing of terfenadine.
Topics: Drug and Narcotic Control; Drug Interactions; Histamine H1 Antagonists; Humans; Tachycardia, Ventric | 1997 |
Risk of ventricular arrhythmias associated with nonsedating antihistamine drugs.
Topics: Adolescent; Adult; Aged; Arrhythmias, Cardiac; Astemizole; Case-Control Studies; Cetirizine; Child; | 1999 |
QT lengthening and life-threatening arrhythmias associated with fexofenadine.
Topics: Aged; Electrocardiography; Histamine H1 Antagonists; Humans; Long QT Syndrome; Male; Syncope; Tachyc | 1999 |