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terfenadine and Atrioventricular Conduction Block

terfenadine has been researched along with Atrioventricular Conduction Block in 2 studies

Terfenadine: A selective histamine H1-receptor antagonist devoid of central nervous system depressant activity. The drug was used for ALLERGY but withdrawn due to causing LONG QT SYNDROME.

Research Excerpts

ExcerptRelevanceReference
"It has been difficult to experimentally reproduce synergistic effects of ketoconazole on terfenadine-induced torsade de pointes."3.96Utilization of the chronic atrioventricular block cynomolgus monkey as an in vivo model to evaluate drug interaction-associated torsade de pointes. ( Chiba, K; Goto, A; Hagiwara-Nagasawa, M; Izumi-Nakaseko, H; Kambayashi, R; Matsumoto, A; Nunoi, Y; Sakamoto, K; Sugiyama, A, 2020)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (50.00)24.3611
2020's1 (50.00)2.80

Authors

AuthorsStudies
Goto, A1
Sakamoto, K1
Hagiwara-Nagasawa, M1
Kambayashi, R1
Chiba, K1
Nunoi, Y1
Izumi-Nakaseko, H1
Matsumoto, A1
Sugiyama, A1
Bobesh, KA1
Renuka, J1
Srilakshmi, RR1
Yellanki, S1
Kulkarni, P1
Yogeeswari, P1
Sriram, D1

Other Studies

2 other studies available for terfenadine and Atrioventricular Conduction Block

ArticleYear
Utilization of the chronic atrioventricular block cynomolgus monkey as an in vivo model to evaluate drug interaction-associated torsade de pointes.
    Journal of pharmacological sciences, 2020, Volume: 142, Issue:4

    Topics: Animals; Atrioventricular Block; Chronic Disease; Disease Models, Animal; Drug Synergism; Ketoconazo

2020
Replacement of cardiotoxic aminopiperidine linker with piperazine moiety reduces cardiotoxicity? Mycobacterium tuberculosis novel bacterial topoisomerase inhibitors.
    Bioorganic & medicinal chemistry, 2016, Jan-01, Volume: 24, Issue:1

    Topics: Animals; Antitubercular Agents; Atrioventricular Block; Cardiotoxicity; DNA Gyrase; Enzyme Assays; E

2016