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terfenadine and Atrial Fibrillation

terfenadine has been researched along with Atrial Fibrillation in 3 studies

Terfenadine: A selective histamine H1-receptor antagonist devoid of central nervous system depressant activity. The drug was used for ALLERGY but withdrawn due to causing LONG QT SYNDROME.

Atrial Fibrillation: Abnormal cardiac rhythm that is characterized by rapid, uncoordinated firing of electrical impulses in the upper chambers of the heart (HEART ATRIA). In such case, blood cannot be effectively pumped into the lower chambers of the heart (HEART VENTRICLES). It is caused by abnormal impulse generation.

Research Excerpts

ExcerptRelevanceReference
"In search of suitable arrhythmia models, we isolated the zebrafish mutation reggae (reg), which displays clinical features of the malignant human short-QT syndrome such as accelerated cardiac repolarization accompanied by cardiac fibrillation."1.35Deficient zebrafish ether-à-go-go-related gene channel gating causes short-QT syndrome in zebrafish reggae mutants. ( Fishman, MC; Friedrich, O; Hassel, D; Just, S; Karle, CA; Katus, HA; Marquart, S; Meder, B; Rottbauer, W; Scholz, EP; Seemann, G; Trano, N; Vogel, B; Weiss, DL; Zitron, E, 2008)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (66.67)18.2507
2000's1 (33.33)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hassel, D1
Scholz, EP1
Trano, N1
Friedrich, O1
Just, S1
Meder, B1
Weiss, DL1
Zitron, E1
Marquart, S1
Vogel, B1
Karle, CA1
Seemann, G1
Fishman, MC1
Katus, HA1
Rottbauer, W1
Woosley, R1
Darrow, WR1
Feroze, H1
Suri, R1
Silverman, DI1

Other Studies

3 other studies available for terfenadine and Atrial Fibrillation

ArticleYear
Deficient zebrafish ether-à-go-go-related gene channel gating causes short-QT syndrome in zebrafish reggae mutants.
    Circulation, 2008, Feb-19, Volume: 117, Issue:7

    Topics: Action Potentials; Amino Acid Substitution; Animals; Arrhythmias, Cardiac; Atrial Fibrillation; Dise

2008
Analysis of potential adverse drug reactions--a case of mistaken identity.
    The American journal of cardiology, 1994, Jul-15, Volume: 74, Issue:2

    Topics: Astemizole; Atrial Fibrillation; Drug Interactions; Electrocardiography; Humans; Loratadine; Quinidi

1994
Torsades de pointes from terfenadine and sotalol given in combination.
    Pacing and clinical electrophysiology : PACE, 1996, Volume: 19, Issue:10

    Topics: Aged; Anti-Arrhythmia Agents; Atrial Fibrillation; Drug Interactions; Electrocardiography; Female; H

1996