terfenadine has been researched along with Asthma, Exercise-Induced in 9 studies
Terfenadine: A selective histamine H1-receptor antagonist devoid of central nervous system depressant activity. The drug was used for ALLERGY but withdrawn due to causing LONG QT SYNDROME.
Asthma, Exercise-Induced: Asthma attacks following a period of exercise. Usually the induced attack is short-lived and regresses spontaneously. The magnitude of postexertional airway obstruction is strongly influenced by the environment in which exercise is performed (i.e. inhalation of cold air during physical exertion markedly augments the severity of the airway obstruction; conversely, warm humid air blunts or abolishes it).
| Excerpt | Relevance | Reference |
|---|---|---|
| "The effect of terfenadine, a selective H1-receptor antagonist devoid of central nervous system side effects, was evaluated on hyperventilation-induced bronchospasm in 11 adult subjects with asthma in a double-blind, placebo-controlled, crossover study." | 9.06 | Attenuation of hyperventilation-induced bronchospasm by terfenadine: a new antihistamine. ( Badier, M; Beaumont, D; Orehek, J, 1988) |
| "The orally active histamine H1 blocker terfenadine was investigated for its effect on resting bronchial tone and exercise induced bronchoconstriction in 20 asthmatic children by a double blind placebo controlled study." | 9.06 | Selective histamine blockade in childhood asthma; the effect of terfenadine on resting bronchial tone and exercise induced bronchoconstriction. ( Heaf, DP; MacFarlane, PI, 1989) |
| "To assess the role of histamine as a mediator in the response to exercise and isocapnic hyperventilation of cold air (IHCA) in asthma, we studied nine asthmatic subjects, age 13 to 25 years." | 7.67 | Effect of terfenadine on the response to exercise and cold air in asthma. ( Chernick, V; Montgomery, M; Pasterkamp, H; Poynter, A; Wiebicke, W, 1988) |
| "Terfenadine or placebo was administered 3 h prior to exercise, and flurbiprofen or placebo was administered 2 h prior to exercise, in a double-blind randomized trial." | 6.67 | Evidence for the roles of histamine and prostaglandins as mediators in exercise-induced asthma: the inhibitory effect of terfenadine and flurbiprofen alone and in combination. ( Finnerty, JP; Holgate, ST, 1990) |
| "The effect of terfenadine, a selective H1-receptor antagonist devoid of central nervous system side effects, was evaluated on hyperventilation-induced bronchospasm in 11 adult subjects with asthma in a double-blind, placebo-controlled, crossover study." | 5.06 | Attenuation of hyperventilation-induced bronchospasm by terfenadine: a new antihistamine. ( Badier, M; Beaumont, D; Orehek, J, 1988) |
| "The orally active histamine H1 blocker terfenadine was investigated for its effect on resting bronchial tone and exercise induced bronchoconstriction in 20 asthmatic children by a double blind placebo controlled study." | 5.06 | Selective histamine blockade in childhood asthma; the effect of terfenadine on resting bronchial tone and exercise induced bronchoconstriction. ( Heaf, DP; MacFarlane, PI, 1989) |
| "To assess the role of histamine as a mediator in the response to exercise and isocapnic hyperventilation of cold air (IHCA) in asthma, we studied nine asthmatic subjects, age 13 to 25 years." | 3.67 | Effect of terfenadine on the response to exercise and cold air in asthma. ( Chernick, V; Montgomery, M; Pasterkamp, H; Poynter, A; Wiebicke, W, 1988) |
| "Terfenadine or placebo was administered 3 h prior to exercise, and flurbiprofen or placebo was administered 2 h prior to exercise, in a double-blind randomized trial." | 2.67 | Evidence for the roles of histamine and prostaglandins as mediators in exercise-induced asthma: the inhibitory effect of terfenadine and flurbiprofen alone and in combination. ( Finnerty, JP; Holgate, ST, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (55.56) | 18.7374 |
| 1990's | 3 (33.33) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (11.11) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Magen, E | 1 |
| Chikovani, T | 1 |
| Patel, KR | 1 |
| Finnerty, JP | 2 |
| Holgate, ST | 2 |
| Anderson, SD | 1 |
| Badier, M | 1 |
| Beaumont, D | 1 |
| Orehek, J | 1 |
| MacFarlane, PI | 1 |
| Heaf, DP | 1 |
| Wiebicke, W | 1 |
| Poynter, A | 1 |
| Montgomery, M | 1 |
| Chernick, V | 1 |
| Pasterkamp, H | 1 |
| MacFarlane, P | 1 |
| Heaf, D | 1 |
5 trials available for terfenadine and Asthma, Exercise-Induced
| Article | Year |
|---|---|
Terfenadine in exercise induced asthma.
Topics: Adolescent; Adult; Asthma; Asthma, Exercise-Induced; Benzhydryl Compounds; Clinical Trials as Topic; | 1984 |
The contribution of histamine release and vagal reflexes, alone and in combination, to exercise-induced asthma.
Topics: Adult; Asthma, Exercise-Induced; Double-Blind Method; Exercise Test; Female; Forced Expiratory Volum | 1993 |
Evidence for the roles of histamine and prostaglandins as mediators in exercise-induced asthma: the inhibitory effect of terfenadine and flurbiprofen alone and in combination.
Topics: Adult; Asthma; Asthma, Exercise-Induced; Benzhydryl Compounds; Double-Blind Method; Exercise Test; F | 1990 |
Attenuation of hyperventilation-induced bronchospasm by terfenadine: a new antihistamine.
Topics: Adolescent; Adult; Asthma, Exercise-Induced; Benzhydryl Compounds; Bronchial Spasm; Clinical Trials | 1988 |
Selective histamine blockade in childhood asthma; the effect of terfenadine on resting bronchial tone and exercise induced bronchoconstriction.
Topics: Adolescent; Airway Resistance; Asthma; Asthma, Exercise-Induced; Benzhydryl Compounds; Bronchi; Chil | 1989 |
4 other studies available for terfenadine and Asthma, Exercise-Induced
| Article | Year |
|---|---|
A case of food-dependent exercise-induced angioedema.
Topics: Adult; Allergens; Angioedema; Animals; Asthma, Exercise-Induced; Cattle; Diet Therapy; Female; Human | 2019 |
Drugs and the control of exercise-induced asthma.
Topics: Adult; Aerosols; Asthma, Exercise-Induced; Bronchodilator Agents; Child; Cromolyn Sodium; Dose-Respo | 1993 |
Effect of terfenadine on the response to exercise and cold air in asthma.
Topics: Adolescent; Adult; Asthma; Asthma, Exercise-Induced; Benzhydryl Compounds; Cold Temperature; Forced | 1988 |
Pre-treatment with terfenadine.
Topics: Asthma; Asthma, Exercise-Induced; Benzhydryl Compounds; Child; Humans; Terfenadine | 1988 |