terfenadine has been researched along with Asthma, Bronchial in 74 studies
Terfenadine: A selective histamine H1-receptor antagonist devoid of central nervous system depressant activity. The drug was used for ALLERGY but withdrawn due to causing LONG QT SYNDROME.
Excerpt | Relevance | Reference |
---|---|---|
"Fourteen atopic patients with mild-to-moderate asthma (forced expiratory volume in 1 second of 76%) completed a double-blind, randomized, crossover study consisting of 3-week treatment blocks of either fluticasone propionate-salmeterol, 250 microg twice daily, or fluticasone propionate alone, 250 microg twice daily, in conjunction with either fexofenadine, 180 mg once daily, or matched placebo." | 9.11 | Addition of fexofenadine to inhaled corticosteroid therapy to reduce inflammatory biomarkers in atopic asthma. ( Fardon, TC; Hodge, MR; Lee, DK; Lipworth, BJ, 2005) |
"It has been reported that acetaldehyde may be a main factor of alcohol-induced bronchoconstriction in Japanese patients with asthma." | 9.07 | Aerosolized acetaldehyde induces histamine-mediated bronchoconstriction in asthmatics. ( Fujimura, M; Matsuda, T; Myou, S; Nishi, K; Ohka, T, 1993) |
"00 h in eight asthmatics 6 h after placebo or terfenadine 120 mg, to determine if diurnal variation in histamine mediated effects contribute to nocturnal bronchoconstriction in asthma." | 9.07 | Effects of H1-receptor blockade with terfenadine in nocturnal asthma. ( Morrison, JF; Pearson, SB; Teale, C, 1991) |
"Acetaldehyde induces bronchial hyperresponsiveness in patients with asthma by mechanisms other than histamine release." | 9.07 | Potentiating effect of inhaled acetaldehyde on bronchial responsiveness to methacholine in asthmatic subjects. ( Fujimura, M; Matsuda, M; Matsuda, T; Myou, S; Nishi, K; Ohka, T, 1994) |
"Neurokinin A (NKA) elicits a potent contractile effect in asthmatic airways." | 9.07 | Effect of oral terfenadine on bronchoconstrictor response to inhaled neurokinin A and histamine in asthmatic subjects. ( Crimi, N; Mistretta, A; Oliveri, R; Palemo, F; Polosa, R; Prosperini, G; Pulvirenti, G, 1993) |
"The bronchodilator effect of terfenadine, 60-mg or 120-mg single dose, and 1 week twice daily dosing, was evaluated in 12 allergic asthmatic patients." | 9.07 | Effect of terfenadine in asthmatic patients. ( Huster, W; Katz, RM; Lee, N; McNutt, B; Rachelefsky, G; Rohr, A; Siegel, S; Spector, S, 1992) |
" We investigated the contribution of the mast cell products, histamine and prostaglandins, to the bronchoconstriction induced by isocapnic hyperventilation (ISH) using single doses of terfenadine, a specific histamine H1-receptor antagonist, and flurbiprofen, a potent cyclooxygenase inhibitor." | 9.07 | The relative contributions of histamine and prostanoids to bronchoconstriction provoked by isocapnic hyperventilation in asthma. ( Finnerty, JP; Harvey, A; Holgate, ST, 1992) |
"The orally active histamine H1 blocker terfenadine was investigated for its effect on resting bronchial tone and exercise induced bronchoconstriction in 20 asthmatic children by a double blind placebo controlled study." | 9.06 | Selective histamine blockade in childhood asthma; the effect of terfenadine on resting bronchial tone and exercise induced bronchoconstriction. ( Heaf, DP; MacFarlane, PI, 1989) |
" Terfenadine, a histamine H1-receptor antagonist, was studied in 52 patients with stable mild perennial asthma with an allergic basis." | 9.06 | Treatment of bronchial asthma with terfenadine; a randomized controlled trial. ( Beaumont, D; Lewis, PJ; Pujet, JC; Sapene, M; Taytard, A, 1987) |
"The dose-response effect of nonsedating H1 histamine-receptor antagonist, terfenadine, administered orally in single doses, was studied on methacholine-induced bronchoconstriction in nine patients with extrinsic bronchial asthma in a double-blind, placebo-controlled, crossover trial." | 9.06 | Effect of terfenadine on methacholine-induced bronchoconstriction in asthma. ( Patel, KR, 1987) |
"We compared the effects of pretreatment of 800 micrograms of inhaled Smith Kline & French (SK&F) 104353, a leukotriene receptor antagonist, and 120 mg of oral terfenadine on the bronchial responses to inhaled histamine in 12 subjects with asthma." | 9.06 | Effects of SK&F 104353, a leukotriene receptor antagonist, on the bronchial responses to histamine in subjects with asthma: a comparative study with terfenadine. ( Dinh Xuan, AT; Lockhart, A; Marsac, J; Regnard, J; Rey, J; Similowski, T, 1990) |
"Inhaled adenosine and adenosine 5'-monophosphate (AMP) cause bronchoconstriction in atopic and nonatopic asthmatics by a mechanism believed to involve histamine release from airway mast cells and an interaction with neural reflexes." | 9.06 | The effect of oral terfenadine alone and in combination with flurbiprofen on the bronchoconstrictor response to inhaled adenosine 5'-monophosphate in nonatopic asthma. ( Holgate, ST; Phillips, GD, 1989) |
"Bradykinin, a nonapeptide cleavage product of high molecular weight kininogen, is a potent bronchoconstrictor agonist in asthma; however, its mechanism of action is not known." | 9.06 | Contribution of histamine and prostanoids to bronchoconstriction provoked by inhaled bradykinin in atopic asthma. ( Holgate, ST; Lai, CK; Phillips, GD; Polosa, R, 1990) |
" We have assessed the effect of a specific histamine H1-receptor antagonist, terfenadine, in the treatment of atopic asthmatics during the grass pollen season." | 9.06 | Terfenadine, a potent histamine H1-receptor antagonist in the treatment of grass pollen sensitive asthma. ( Holgate, ST; Jackson, L; Rafferty, P; Smith, R, 1990) |
"We have investigated the effect of a specific H1-receptor antagonist, terfenadine, on antigen-induced asthma." | 9.06 | Effect of an oral H1-receptor antagonist, terfenadine, on antigen-induced asthma. ( Chan, TB; Eiser, NM; Shelton, DM, 1986) |
"Because the older antihistamines possessed relatively weak antihistaminic action, as well as sedative and anticholinergic effects, they could not be administered in doses high enough to confer relief to atopic patients with asthma." | 8.78 | Antihistamines in the treatment of clinical asthma. ( Rafferty, P, 1990) |
"Bronchodilatation data from three, four-period cross-over studies were combined to assess the effect of oral terfenadine 60, 120, 180 mg and placebo on the airways of 26 patients with atopic asthma." | 7.68 | Lack of dose-response effect of terfenadine on resting bronchomotor tone in patients with asthma. ( Ghosh, SK; Matcham, J; Patel, KR, 1991) |
" To investigate this further we have determined that, in eight mild atopic asthmatic subjects, terfenadine (180 mg), administered 3 hr pre-challenge, increases the geometric mean PC20 for histamine from 0." | 7.67 | The effect of histamine-H1 receptor antagonism with terfenadine on concentration-related AMP-induced bronchoconstriction in asthma. ( Holgate, ST; Phillips, GD; Polosa, R, 1989) |
"We have attempted to use a potent and selective histamine H1-receptor antagonist terfenadine to allow a larger dose of allergen to be administered to previous single early responders to investigate if an increased dose of allergen could induce a late asthmatic response." | 7.67 | The effect of an increase in inhaled allergen dose after terfenadine on the occurrence and magnitude of the late asthmatic response. ( Beasley, R; Holgate, ST; Lai, CK, 1989) |
"To assess the role of histamine as a mediator in the response to exercise and isocapnic hyperventilation of cold air (IHCA) in asthma, we studied nine asthmatic subjects, age 13 to 25 years." | 7.67 | Effect of terfenadine on the response to exercise and cold air in asthma. ( Chernick, V; Montgomery, M; Pasterkamp, H; Poynter, A; Wiebicke, W, 1988) |
" Eight patients with alcohol-induced asthma received terfenadine (60 mg, twice on the test day) or placebo, with the last dosing 2 h before the test in a double-blind, randomized, cross-over manner." | 6.68 | Inhibitory effect of terfenadine, a selective H1 histamine antagonist, on alcoholic beverage-induced bronchoconstriction in asthmatic patients. ( Fujimura, M; Matsuda, T; Myou, S; Nishi, K; Ohka, T, 1995) |
"Terfenadine or placebo was administered 3 h prior to exercise, and flurbiprofen or placebo was administered 2 h prior to exercise, in a double-blind randomized trial." | 6.67 | Evidence for the roles of histamine and prostaglandins as mediators in exercise-induced asthma: the inhibitory effect of terfenadine and flurbiprofen alone and in combination. ( Finnerty, JP; Holgate, ST, 1990) |
"Terfenadine (Seldane) is a new, highly potent H1 histamine receptor antagonist that in clinically effective doses is free of side effects." | 6.66 | Terfenadine (Seldane) is a potent and selective histamine H1 receptor antagonist in asthmatic airways. ( Holgate, ST; Rafferty, P, 1987) |
"Among patients in whom coughing developed during the peak pollen season, airway responsiveness significantly increased in the fexofenadine group." | 5.14 | Effects of pranlukast hydrate on airway hyperresponsiveness in non-asthmatic patients with Japanese cedar pollinosis. ( Fukuda, T; Kashima, R; Okada, T; Sagara, H; Yukawa, T, 2009) |
"We elected to evaluate the effects of repeated dosing with fexofenadine (FEX) and montelukast (ML) at clinically recommended doses in ICS-treated asthmatic patients using adenosine monophosphate (AMP) bronchial challenge as the primary outcome." | 5.11 | Repeated dosing effects of mediator antagonists in inhaled corticosteroid-treated atopic asthmatic patients. ( Haggart, K; Jackson, CM; Lee, DK; Lipworth, BJ, 2004) |
"Fourteen atopic patients with mild-to-moderate asthma (forced expiratory volume in 1 second of 76%) completed a double-blind, randomized, crossover study consisting of 3-week treatment blocks of either fluticasone propionate-salmeterol, 250 microg twice daily, or fluticasone propionate alone, 250 microg twice daily, in conjunction with either fexofenadine, 180 mg once daily, or matched placebo." | 5.11 | Addition of fexofenadine to inhaled corticosteroid therapy to reduce inflammatory biomarkers in atopic asthma. ( Fardon, TC; Hodge, MR; Lee, DK; Lipworth, BJ, 2005) |
"Sixteen atopic patients with mild-to-moderate asthma of whom 10 were receiving inhaled corticosteroid therapy (all had positive results to house dust mite on skin prick testing) were randomized in a double-blind, placebo-controlled, cross-over fashion to receive single doses of 5 mg of desloratadine, 180 mg of fexofenadine hydrochloride (FEX), 5 mg of levocetirizine dihydrochloride (LEV), or placebo, with AMP challenge performed 12 hours after dosing." | 5.10 | Comparative in vivo bioactivity of modern H1-antihistamines on AMP challenge in atopic asthma. ( Bates, CE; Currie, GP; Lee, DK; Lipworth, BJ, 2003) |
"We studied, separately, the effects of the histamine antagonist, fexofenadine hydrochloride, and the leukotriene antagonist, montelukast sodium, and their placebos on airway sensitivity to and recovery from inhaled mannitol in subjects with asthma." | 5.09 | Fexofenadine decreases sensitivity to and montelukast improves recovery from inhaled mannitol. ( Anderson, SD; Brannan, JD; Chan, HK; Gomes, K; King, GG; Seale, JP, 2001) |
"The bronchodilator effect of terfenadine, 60-mg or 120-mg single dose, and 1 week twice daily dosing, was evaluated in 12 allergic asthmatic patients." | 5.07 | Effect of terfenadine in asthmatic patients. ( Huster, W; Katz, RM; Lee, N; McNutt, B; Rachelefsky, G; Rohr, A; Siegel, S; Spector, S, 1992) |
" We investigated the contribution of the mast cell products, histamine and prostaglandins, to the bronchoconstriction induced by isocapnic hyperventilation (ISH) using single doses of terfenadine, a specific histamine H1-receptor antagonist, and flurbiprofen, a potent cyclooxygenase inhibitor." | 5.07 | The relative contributions of histamine and prostanoids to bronchoconstriction provoked by isocapnic hyperventilation in asthma. ( Finnerty, JP; Harvey, A; Holgate, ST, 1992) |
"Ten patients with stable chronic asthma completed a randomized double-blind placebo controlled crossover study examining the effect of 120mg terfenadine twice daily for 4 weeks on bronchial responsiveness." | 5.07 | Lack of effect of 4 weeks of oral H1 antagonist on bronchial responsiveness. ( Latimer, KM; Ruffin, RE, 1991) |
"00 h in eight asthmatics 6 h after placebo or terfenadine 120 mg, to determine if diurnal variation in histamine mediated effects contribute to nocturnal bronchoconstriction in asthma." | 5.07 | Effects of H1-receptor blockade with terfenadine in nocturnal asthma. ( Morrison, JF; Pearson, SB; Teale, C, 1991) |
"Twenty-four adult asthmatic subjects were included in a parallel group study that compared the duration of effect of two antihistamines and a placebo on cutaneous and inhaled reactivity to histamine." | 5.07 | Duration of effect of loratadine and terfenadine administered once a day for one week on cutaneous and inhaled reactivity to histamine. ( Cartier, A; Ghezzo, H; L'Archevêque, J; Labrecque, M; Malo, JL; Trudeau, C, 1993) |
"It has been reported that acetaldehyde may be a main factor of alcohol-induced bronchoconstriction in Japanese patients with asthma." | 5.07 | Aerosolized acetaldehyde induces histamine-mediated bronchoconstriction in asthmatics. ( Fujimura, M; Matsuda, T; Myou, S; Nishi, K; Ohka, T, 1993) |
"Acetaldehyde induces bronchial hyperresponsiveness in patients with asthma by mechanisms other than histamine release." | 5.07 | Potentiating effect of inhaled acetaldehyde on bronchial responsiveness to methacholine in asthmatic subjects. ( Fujimura, M; Matsuda, M; Matsuda, T; Myou, S; Nishi, K; Ohka, T, 1994) |
"Neurokinin A (NKA) elicits a potent contractile effect in asthmatic airways." | 5.07 | Effect of oral terfenadine on bronchoconstrictor response to inhaled neurokinin A and histamine in asthmatic subjects. ( Crimi, N; Mistretta, A; Oliveri, R; Palemo, F; Polosa, R; Prosperini, G; Pulvirenti, G, 1993) |
" We have assessed the effect of a specific histamine H1-receptor antagonist, terfenadine, in the treatment of atopic asthmatics during the grass pollen season." | 5.06 | Terfenadine, a potent histamine H1-receptor antagonist in the treatment of grass pollen sensitive asthma. ( Holgate, ST; Jackson, L; Rafferty, P; Smith, R, 1990) |
"Bradykinin, a nonapeptide cleavage product of high molecular weight kininogen, is a potent bronchoconstrictor agonist in asthma; however, its mechanism of action is not known." | 5.06 | Contribution of histamine and prostanoids to bronchoconstriction provoked by inhaled bradykinin in atopic asthma. ( Holgate, ST; Lai, CK; Phillips, GD; Polosa, R, 1990) |
"In a study designed to determine the protective effect of the specific histamine H1 antagonist terfenadine on hypertonic saline induced bronchoconstriction, 10 asthmatic subjects underwent hypertonic saline challenge (3." | 5.06 | Role of histamine release in hypertonic saline induced bronchoconstriction. ( Belcher, NG; Lee, TH; O'Hickey, SP; Rees, PJ, 1989) |
"Inhaled adenosine and adenosine 5'-monophosphate (AMP) cause bronchoconstriction in atopic and nonatopic asthmatics by a mechanism believed to involve histamine release from airway mast cells and an interaction with neural reflexes." | 5.06 | The effect of oral terfenadine alone and in combination with flurbiprofen on the bronchoconstrictor response to inhaled adenosine 5'-monophosphate in nonatopic asthma. ( Holgate, ST; Phillips, GD, 1989) |
"The orally active histamine H1 blocker terfenadine was investigated for its effect on resting bronchial tone and exercise induced bronchoconstriction in 20 asthmatic children by a double blind placebo controlled study." | 5.06 | Selective histamine blockade in childhood asthma; the effect of terfenadine on resting bronchial tone and exercise induced bronchoconstriction. ( Heaf, DP; MacFarlane, PI, 1989) |
"The dose-response effect of nonsedating H1 histamine-receptor antagonist, terfenadine, administered orally in single doses, was studied on methacholine-induced bronchoconstriction in nine patients with extrinsic bronchial asthma in a double-blind, placebo-controlled, crossover trial." | 5.06 | Effect of terfenadine on methacholine-induced bronchoconstriction in asthma. ( Patel, KR, 1987) |
" To investigate the possibility that benzalkonium chloride-induced bronchoconstriction results from the endogenous release of histamine, we examined the effect of the selective histamine antagonists terfenadine and astemizole, on the airways response to inhaled benzalkonium chloride and histamine in 12 asthmatic subjects." | 5.06 | The contribution of histamine release to bronchoconstriction provoked by inhaled benzalkonium chloride in asthma. ( Beasley, R; Holgate, ST; Miszkiel, KA; Rafferty, P, 1988) |
"We have investigated the effect of a specific H1-receptor antagonist, terfenadine, on antigen-induced asthma." | 5.06 | Effect of an oral H1-receptor antagonist, terfenadine, on antigen-induced asthma. ( Chan, TB; Eiser, NM; Shelton, DM, 1986) |
"We compared the effects of pretreatment of 800 micrograms of inhaled Smith Kline & French (SK&F) 104353, a leukotriene receptor antagonist, and 120 mg of oral terfenadine on the bronchial responses to inhaled histamine in 12 subjects with asthma." | 5.06 | Effects of SK&F 104353, a leukotriene receptor antagonist, on the bronchial responses to histamine in subjects with asthma: a comparative study with terfenadine. ( Dinh Xuan, AT; Lockhart, A; Marsac, J; Regnard, J; Rey, J; Similowski, T, 1990) |
"The effect of flurbiprofen, a potent cyclo-oxygenase inhibitor, on histamine and methacholine reactivity was assessed in seven atopic subjects with asthma." | 5.06 | Effects of a cyclo-oxygenase inhibitor, flurbiprofen, and an H1 histamine receptor antagonist, terfenadine, alone and in combination on allergen induced immediate bronchoconstriction in man. ( Curzen, N; Holgate, ST; Rafferty, P, 1987) |
" Terfenadine, a histamine H1-receptor antagonist, was studied in 52 patients with stable mild perennial asthma with an allergic basis." | 5.06 | Treatment of bronchial asthma with terfenadine; a randomized controlled trial. ( Beaumont, D; Lewis, PJ; Pujet, JC; Sapene, M; Taytard, A, 1987) |
"Since tranilast, the first inhibitor of chemical mediator (ICMR), had been assessed to be as effective as disodium cromogycate in asthma, several orally active ICMRs, which have no antihistamine or bronchodilator effect, have been developed and prescribed for asthma control in Japan." | 4.79 | [Inhibitor of chemical mediator release]. ( Fujimura, M, 1996) |
"Because the older antihistamines possessed relatively weak antihistaminic action, as well as sedative and anticholinergic effects, they could not be administered in doses high enough to confer relief to atopic patients with asthma." | 4.78 | Antihistamines in the treatment of clinical asthma. ( Rafferty, P, 1990) |
"Bronchodilatation data from three, four-period cross-over studies were combined to assess the effect of oral terfenadine 60, 120, 180 mg and placebo on the airways of 26 patients with atopic asthma." | 3.68 | Lack of dose-response effect of terfenadine on resting bronchomotor tone in patients with asthma. ( Ghosh, SK; Matcham, J; Patel, KR, 1991) |
" Allergic bronchial eosinophilia in guinea pigs was inhibited by orally administered dexamethasone and methylprednisolone." | 3.68 | Allergic bronchial eosinophilia: a therapeutic approach for the selection of potential bronchial anti-inflammatory drugs. ( Chand, N; De Vine, CL; Diamantis, W; Harrison, JE; Jakubicki, RG; Nolan, KW; Pillar, J; Rooney, SM; Sofia, RD, 1993) |
"We measured the bronchial response to histamine in 26 allergic asthmatics and 17 healthy subjects before and after the bronchial pretreatment with selective H2-receptor antagonist ranitidine." | 3.68 | [A study on the relationship between histamine receptors and bronchial hyperresponsiveness in asthma]. ( Wang, SZ, 1991) |
"We have attempted to use a potent and selective histamine H1-receptor antagonist terfenadine to allow a larger dose of allergen to be administered to previous single early responders to investigate if an increased dose of allergen could induce a late asthmatic response." | 3.67 | The effect of an increase in inhaled allergen dose after terfenadine on the occurrence and magnitude of the late asthmatic response. ( Beasley, R; Holgate, ST; Lai, CK, 1989) |
" To investigate this further we have determined that, in eight mild atopic asthmatic subjects, terfenadine (180 mg), administered 3 hr pre-challenge, increases the geometric mean PC20 for histamine from 0." | 3.67 | The effect of histamine-H1 receptor antagonism with terfenadine on concentration-related AMP-induced bronchoconstriction in asthma. ( Holgate, ST; Phillips, GD; Polosa, R, 1989) |
"Until the appearance of nonsedating antihistamines such as terfenadine and astemizole, clinical studies of H1 antagonists in the treatment of asthma yielded disappointing results." | 3.67 | The European experience with antihistamines in asthma. ( Rafferty, P, 1989) |
"To assess the role of histamine as a mediator in the response to exercise and isocapnic hyperventilation of cold air (IHCA) in asthma, we studied nine asthmatic subjects, age 13 to 25 years." | 3.67 | Effect of terfenadine on the response to exercise and cold air in asthma. ( Chernick, V; Montgomery, M; Pasterkamp, H; Poynter, A; Wiebicke, W, 1988) |
" However, the effect of long-term use of montelukast, a cystenil leukotriene receptor antagonist, on skin prick test hasn't been full elucidated." | 2.78 | The effect of montelukast on wheal reactions in skin prick tests: a double-blind-placebo-controlled randomized trial. ( Aydogan, M; Aydogmus, CY; Bulan, K; Siraneci, R, 2013) |
"Fexofenadine, 15, 30, and 60 mg twice daily, was safe and well tolerated in this large pediatric patient population." | 2.70 | Safety of fexofenadine in children treated for seasonal allergic rhinitis. ( Bernstein, DI; Goldsobel, A; Graft, DF; Long, J; Meltzer, EO; Portnoy, J, 2001) |
" Eight patients with alcohol-induced asthma received terfenadine (60 mg, twice on the test day) or placebo, with the last dosing 2 h before the test in a double-blind, randomized, cross-over manner." | 2.68 | Inhibitory effect of terfenadine, a selective H1 histamine antagonist, on alcoholic beverage-induced bronchoconstriction in asthmatic patients. ( Fujimura, M; Matsuda, T; Myou, S; Nishi, K; Ohka, T, 1995) |
"Terfenadine or placebo was administered 3 h prior to exercise, and flurbiprofen or placebo was administered 2 h prior to exercise, in a double-blind randomized trial." | 2.67 | Evidence for the roles of histamine and prostaglandins as mediators in exercise-induced asthma: the inhibitory effect of terfenadine and flurbiprofen alone and in combination. ( Finnerty, JP; Holgate, ST, 1990) |
"Terfenadine (Seldane) is a new, highly potent H1 histamine receptor antagonist that in clinically effective doses is free of side effects." | 2.66 | Terfenadine (Seldane) is a potent and selective histamine H1 receptor antagonist in asthmatic airways. ( Holgate, ST; Rafferty, P, 1987) |
" This was conducted, first as a dose-response study and, second, as a time-course study." | 2.66 | Inhibition of hypertonic saline-induced bronchoconstriction by terfenadine and flurbiprofen. Evidence for the predominant role of histamine. ( Finnerty, JP; Holgate, ST; Wilmot, C, 1989) |
"Terfenadine is a selective H1-histamine receptor antagonist." | 2.37 | Terfenadine. A review of its pharmacodynamic properties and therapeutic efficacy. ( Heel, RC; Sorkin, EM, 1985) |
" Terfenadine, at concentrations achievable at standard dosing regimens, has anti-inflammatory properties in vitro." | 1.29 | Effect of terfenadine on human eosinophil and neutrophil chemotactic response and generation of superoxide. ( Eda, R; Hopp, RJ; Townley, RG, 1994) |
" The cumulative results indicate that the nonsedative antihistamine terfenadine, given orally at a dosage of 60 mg twice daily, is effective in the treatment of seasonal allergic rhinitis in both adults and children." | 1.27 | The use of antihistamines for the treatment of airway disease. ( Meltzer, EO, 1988) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 26 (35.14) | 18.7374 |
1990's | 33 (44.59) | 18.2507 |
2000's | 14 (18.92) | 29.6817 |
2010's | 1 (1.35) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Bulan, K | 1 |
Aydogan, M | 1 |
Siraneci, R | 1 |
Aydogmus, CY | 1 |
Izumi, N | 1 |
Mizuguchi, H | 1 |
Umehara, H | 1 |
Ogino, S | 1 |
Fukui, H | 1 |
Sagara, H | 1 |
Yukawa, T | 1 |
Kashima, R | 1 |
Okada, T | 1 |
Fukuda, T | 1 |
Li, AM | 1 |
Abdullah, VJ | 1 |
Tsen, CS | 1 |
Au, CT | 1 |
Lam, HS | 1 |
So, HK | 1 |
Chan, MH | 1 |
Leung, AW | 1 |
Chan, IH | 1 |
Lam, CW | 1 |
Ng, PC | 1 |
Shaikh, WA | 1 |
Shaikh, SW | 1 |
Lee, DK | 3 |
Bates, CE | 1 |
Currie, GP | 1 |
Lipworth, BJ | 3 |
Grzelewska-Rzymowska, I | 1 |
Kroczyńska-Bednarek, J | 1 |
Pietrzkowicz, M | 1 |
Li, DR | 1 |
Jackson, CM | 1 |
Haggart, K | 1 |
Fardon, TC | 1 |
Hodge, MR | 1 |
Patel, KR | 3 |
Myou, S | 3 |
Fujimura, M | 4 |
Nishi, K | 3 |
Ohka, T | 3 |
Matsuda, T | 3 |
Wood-Baker, R | 1 |
Smith, R | 2 |
Holgate, ST | 16 |
Tasaka, K | 2 |
Tomioka, H | 1 |
Lulich, KM | 1 |
Paterson, JW | 1 |
Goldie, RG | 1 |
Matsuda, M | 1 |
Eda, R | 1 |
Townley, RG | 5 |
Hopp, RJ | 3 |
Crimi, N | 1 |
Oliveri, R | 1 |
Polosa, R | 4 |
Pulvirenti, G | 1 |
Prosperini, G | 1 |
Palemo, F | 1 |
Mistretta, A | 1 |
Chand, N | 1 |
Harrison, JE | 1 |
Rooney, SM | 1 |
Nolan, KW | 1 |
De Vine, CL | 1 |
Jakubicki, RG | 1 |
Pillar, J | 1 |
Diamantis, W | 1 |
Sofia, RD | 1 |
Masheter, HC | 1 |
Labrecque, M | 1 |
Ghezzo, H | 1 |
L'Archevêque, J | 1 |
Trudeau, C | 1 |
Cartier, A | 1 |
Malo, JL | 1 |
Gupta, SK | 1 |
Brannan, JD | 1 |
Anderson, SD | 2 |
Gomes, K | 1 |
King, GG | 1 |
Chan, HK | 1 |
Seale, JP | 1 |
Graft, DF | 1 |
Bernstein, DI | 1 |
Goldsobel, A | 1 |
Meltzer, EO | 2 |
Portnoy, J | 1 |
Long, J | 1 |
Takizawa, T | 1 |
Watanabe, C | 1 |
Saiki, I | 1 |
Wada, Y | 1 |
Tohma, T | 1 |
Nagai, H | 1 |
Wilson, AM | 1 |
Wood, SF | 1 |
Spector, S | 1 |
Lee, N | 1 |
McNutt, B | 1 |
Katz, RM | 1 |
Huster, W | 1 |
Siegel, S | 1 |
Rachelefsky, G | 1 |
Rohr, A | 1 |
Finnerty, JP | 3 |
Harvey, A | 1 |
Ciprandi, G | 1 |
Tosca, MA | 1 |
Iudice, A | 1 |
Buscaglia, S | 1 |
Fasce, L | 1 |
Canonica, GW | 1 |
Phillips, GD | 5 |
Rajakulasingam, K | 1 |
Ghosh, SK | 1 |
Matcham, J | 1 |
Ruffin, RE | 1 |
Latimer, KM | 1 |
Hamid, M | 1 |
Rafferty, P | 8 |
Eiser, N | 1 |
Teale, C | 1 |
Morrison, JF | 1 |
Pearson, SB | 1 |
Wang, SZ | 1 |
Agrawal, DK | 2 |
Bewtra, AK | 2 |
Lai, CK | 2 |
Dinh Xuan, AT | 1 |
Regnard, J | 1 |
Similowski, T | 1 |
Rey, J | 1 |
Marsac, J | 1 |
Lockhart, A | 1 |
Finney, MJ | 1 |
Black, JL | 1 |
Jackson, L | 1 |
Dijkman, JH | 1 |
Hekking, PR | 1 |
Molkenboer, JF | 1 |
Nierop, G | 1 |
Vanderschueren, R | 1 |
Bernheim, J | 1 |
Van Ganse, EH | 1 |
Akagi, M | 1 |
Mio, M | 1 |
Miyoshi, K | 1 |
Miszkiel, KA | 1 |
Beasley, R | 4 |
Church, MM | 1 |
Lai, C | 1 |
Featherstone, RL | 1 |
Nabe, M | 1 |
Sarmiento, EU | 1 |
O'Hickey, SP | 1 |
Belcher, NG | 1 |
Rees, PJ | 1 |
Lee, TH | 1 |
Nair, NM | 1 |
Lantin, JP | 1 |
Pécoud, A | 1 |
Wilmot, C | 1 |
MacFarlane, PI | 1 |
Heaf, DP | 1 |
Sorkin, EM | 1 |
Heel, RC | 1 |
Fink, P | 1 |
von Minckwitz, A | 1 |
Roser, E | 1 |
Ruge, H | 1 |
Cookson, WO | 1 |
Chan, TB | 1 |
Shelton, DM | 1 |
Eiser, NM | 1 |
Curzen, N | 1 |
Wiebicke, W | 1 |
Poynter, A | 1 |
Montgomery, M | 1 |
Chernick, V | 1 |
Pasterkamp, H | 1 |
Taytard, A | 1 |
Beaumont, D | 1 |
Pujet, JC | 1 |
Sapene, M | 1 |
Lewis, PJ | 1 |
MacFarlane, P | 1 |
Heaf, D | 1 |
7 reviews available for terfenadine and Asthma, Bronchial
Article | Year |
---|---|
Terfenadine. The first nonsedating antihistamine.
Topics: Adult; Asthma; Child; Drug Interactions; Electroencephalography; Humans; Rhinitis; Skin Tests; Terfe | 1993 |
[Inhibitor of chemical mediator release].
Topics: Asthma; Clinical Trials as Topic; Depression, Chemical; Double-Blind Method; Histamine H1 Antagonist | 1996 |
Are antihistamines useful in managing asthma?
Topics: Acetates; Anti-Inflammatory Agents, Non-Steroidal; Asthma; Bronchospirometry; Cetirizine; Cyclopropa | 2002 |
Antiallergic properties of the second-generation H1 antihistamines during the early and late reactions to antigen.
Topics: Antigens; Asthma; Cetirizine; Chemotaxis, Leukocyte; Cold Temperature; Forced Expiratory Volume; His | 1992 |
Clinical experience with non-sedating antihistamines in paediatric allergic rhinitis.
Topics: Adolescent; Astemizole; Asthma; Child; Child, Preschool; Chlorpheniramine; Clinical Trials as Topic; | 1992 |
Antihistamines in the treatment of clinical asthma.
Topics: Animals; Asthma; Benzhydryl Compounds; Cetirizine; Dose-Response Relationship, Drug; Forced Expirato | 1990 |
Terfenadine. A review of its pharmacodynamic properties and therapeutic efficacy.
Topics: Animals; Asthma; Benzhydryl Compounds; Histamine H1 Antagonists; Humans; Hypnotics and Sedatives; Ki | 1985 |
43 trials available for terfenadine and Asthma, Bronchial
Article | Year |
---|---|
The effect of montelukast on wheal reactions in skin prick tests: a double-blind-placebo-controlled randomized trial.
Topics: Acetates; Allergens; Animals; Asthma; Chi-Square Distribution; Child; Cyclopropanes; Dose-Response R | 2013 |
Effects of pranlukast hydrate on airway hyperresponsiveness in non-asthmatic patients with Japanese cedar pollinosis.
Topics: Acetylcholine; Activities of Daily Living; Adult; Anti-Allergic Agents; Anti-Asthmatic Agents; Antig | 2009 |
Leukotriene receptor antagonist in the treatment of childhood allergic rhinitis--a randomized placebo-controlled study.
Topics: Acetates; Adolescent; Asthma; Child; Cyclopropanes; Double-Blind Method; Drug Therapy, Combination; | 2009 |
Comparative in vivo bioactivity of modern H1-antihistamines on AMP challenge in atopic asthma.
Topics: Acetates; Adenosine Monophosphate; Adult; Aged; Asthma; Bronchial Provocation Tests; Cetirizine; Cro | 2003 |
[Observation on effect of integrative Chinese and Western medicine in treating acute attack of bronchial asthma].
Topics: Adolescent; Adult; Aged; Anti-Asthmatic Agents; Asthma; Drug Therapy, Combination; Drugs, Chinese He | 2003 |
Repeated dosing effects of mediator antagonists in inhaled corticosteroid-treated atopic asthmatic patients.
Topics: Acetates; Adenosine Monophosphate; Administration, Inhalation; Adrenal Cortex Hormones; Anti-Allergi | 2004 |
Addition of fexofenadine to inhaled corticosteroid therapy to reduce inflammatory biomarkers in atopic asthma.
Topics: Adenosine Monophosphate; Administration, Inhalation; Adolescent; Adrenal Cortex Hormones; Adult; Alb | 2005 |
Terfenadine in exercise induced asthma.
Topics: Adolescent; Adult; Asthma; Asthma, Exercise-Induced; Benzhydryl Compounds; Clinical Trials as Topic; | 1984 |
Inhibitory effect of terfenadine, a selective H1 histamine antagonist, on alcoholic beverage-induced bronchoconstriction in asthmatic patients.
Topics: Adult; Alcoholic Beverages; Asthma; Beer; Bronchial Provocation Tests; Bronchoconstriction; Cross-Ov | 1995 |
A double-blind, placebo controlled study of the effect of the specific histamine H1-receptor antagonist, terfenadine, in chronic severe asthma.
Topics: Adult; Analysis of Variance; Asthma; Chronic Disease; Cross-Over Studies; Double-Blind Method; Femal | 1995 |
The Japanese perspective: effects of terfenadine in bronchial asthma: in vitro and in vivo research.
Topics: Adult; Airway Resistance; Animals; Asthma; Female; Guinea Pigs; Histamine Release; Humans; Japan; Ke | 1993 |
Aerosolized acetaldehyde induces histamine-mediated bronchoconstriction in asthmatics.
Topics: Acetaldehyde; Adult; Aerosols; Analysis of Variance; Asthma; Bronchial Provocation Tests; Bronchocon | 1993 |
Potentiating effect of inhaled acetaldehyde on bronchial responsiveness to methacholine in asthmatic subjects.
Topics: Acetaldehyde; Adult; Aged; Asthma; Bronchi; Bronchial Hyperreactivity; Bronchial Provocation Tests; | 1994 |
Effect of oral terfenadine on bronchoconstrictor response to inhaled neurokinin A and histamine in asthmatic subjects.
Topics: Administration, Oral; Adolescent; Adult; Asthma; Bronchial Provocation Tests; Bronchoconstriction; B | 1993 |
Duration of effect of loratadine and terfenadine administered once a day for one week on cutaneous and inhaled reactivity to histamine.
Topics: Administration, Inhalation; Adult; Aged; Asthma; Bronchoconstriction; Dose-Response Relationship, Dr | 1993 |
Reversion and antihistamines.
Topics: Anti-Asthmatic Agents; Asthma; Beclomethasone; Cetirizine; Cromolyn Sodium; Glucocorticoids; Histami | 1996 |
Fexofenadine decreases sensitivity to and montelukast improves recovery from inhaled mannitol.
Topics: Acetates; Administration, Inhalation; Adolescent; Adult; Aged; Anti-Asthmatic Agents; Asthma; Bronch | 2001 |
Safety of fexofenadine in children treated for seasonal allergic rhinitis.
Topics: Asthma; Child; Double-Blind Method; Humans; Rhinitis, Allergic, Seasonal; Terfenadine; Therapeutic E | 2001 |
Effect of terfenadine in asthmatic patients.
Topics: Asthma; Double-Blind Method; Forced Expiratory Volume; Humans; Terfenadine | 1992 |
The relative contributions of histamine and prostanoids to bronchoconstriction provoked by isocapnic hyperventilation in asthma.
Topics: Adolescent; Adult; Asthma; Bronchial Provocation Tests; Bronchoconstriction; Double-Blind Method; Fe | 1992 |
The effect of inhaled ipratropium bromide alone and in combination with oral terfenadine on bronchoconstriction provoked by adenosine 5'-monophosphate and histamine in asthma.
Topics: Adenosine Monophosphate; Administration, Inhalation; Administration, Oral; Adult; Asthma; Benzhydryl | 1991 |
Lack of effect of 4 weeks of oral H1 antagonist on bronchial responsiveness.
Topics: Administration, Oral; Adult; Asthma; Bronchoconstriction; Chronic Disease; Double-Blind Method; Drug | 1991 |
The inhibitory effect of terfenadine and flurbiprofen on early and late-phase bronchoconstriction following allergen challenge in atopic asthma.
Topics: Adolescent; Adult; Allergens; Asthma; Benzhydryl Compounds; Bronchial Provocation Tests; Female; Flu | 1990 |
Evidence for the roles of histamine and prostaglandins as mediators in exercise-induced asthma: the inhibitory effect of terfenadine and flurbiprofen alone and in combination.
Topics: Adult; Asthma; Asthma, Exercise-Induced; Benzhydryl Compounds; Double-Blind Method; Exercise Test; F | 1990 |
The effect of a beta 2-adrenergic agonist and a histamine H1-receptor antagonist on the late asthmatic response to inhaled antigen.
Topics: Administration, Inhalation; Adult; Albuterol; Animals; Antigens; Asthma; Bronchial Provocation Tests | 1991 |
Effects of H1-receptor blockade with terfenadine in nocturnal asthma.
Topics: Adult; Aged; Asthma; Circadian Rhythm; Female; Humans; Male; Middle Aged; Placebos; Receptors, Hista | 1991 |
Terfenadine effect on the bronchoconstriction, dermal response, and leukopenia induced by platelet-activating factor.
Topics: Asthma; Bronchial Provocation Tests; Bronchoconstriction; Double-Blind Method; Histamine; Humans; Le | 1991 |
Contribution of histamine and prostanoids to bronchoconstriction provoked by inhaled bradykinin in atopic asthma.
Topics: Adult; Asthma; Benzhydryl Compounds; Bradykinin; Bronchial Provocation Tests; Female; Flurbiprofen; | 1990 |
Effects of SK&F 104353, a leukotriene receptor antagonist, on the bronchial responses to histamine in subjects with asthma: a comparative study with terfenadine.
Topics: Adult; Asthma; Benzhydryl Compounds; Blood Pressure; Bronchi; Clinical Trials as Topic; Dicarboxylic | 1990 |
Terfenadine modifies airway narrowing induced by the inhalation of nonisotonic aerosols in subjects with asthma.
Topics: Adult; Aerosols; Asthma; Benzhydryl Compounds; Bronchi; Female; Forced Expiratory Volume; Histamine | 1990 |
Terfenadine, a potent histamine H1-receptor antagonist in the treatment of grass pollen sensitive asthma.
Topics: Adult; Asthma; Benzhydryl Compounds; Double-Blind Method; Female; Histamine H1 Antagonists; Humans; | 1990 |
Prophylactic treatment of grass pollen-induced asthma with cetirizine.
Topics: Adolescent; Adult; Aged; Asthma; Benzhydryl Compounds; Cetirizine; Child; Double-Blind Method; Femal | 1990 |
The contribution of histamine release to bronchoconstriction provoked by inhaled benzalkonium chloride in asthma.
Topics: Adult; Astemizole; Asthma; Benzalkonium Compounds; Benzhydryl Compounds; Benzimidazoles; Bronchial P | 1988 |
Role of histamine release in hypertonic saline induced bronchoconstriction.
Topics: Adult; Asthma; Benzhydryl Compounds; Bronchi; Dose-Response Relationship, Drug; Female; Forced Expir | 1989 |
The effect of oral terfenadine alone and in combination with flurbiprofen on the bronchoconstrictor response to inhaled adenosine 5'-monophosphate in nonatopic asthma.
Topics: Adenosine Monophosphate; Administration, Inhalation; Administration, Oral; Asthma; Benzhydryl Compou | 1989 |
Inhibition of hypertonic saline-induced bronchoconstriction by terfenadine and flurbiprofen. Evidence for the predominant role of histamine.
Topics: Adult; Asthma; Benzhydryl Compounds; Bronchi; Bronchial Provocation Tests; Dose-Response Relationshi | 1989 |
Selective histamine blockade in childhood asthma; the effect of terfenadine on resting bronchial tone and exercise induced bronchoconstriction.
Topics: Adolescent; Airway Resistance; Asthma; Asthma, Exercise-Induced; Benzhydryl Compounds; Bronchi; Chil | 1989 |
Terfenadine (Seldane) is a potent and selective histamine H1 receptor antagonist in asthmatic airways.
Topics: Adult; Asthma; Benzhydryl Compounds; Bronchi; Bronchial Provocation Tests; Clinical Trials as Topic; | 1987 |
Effect of terfenadine on methacholine-induced bronchoconstriction in asthma.
Topics: Adolescent; Adult; Asthma; Benzhydryl Compounds; Clinical Trials as Topic; Dose-Response Relationshi | 1987 |
[Terfenadine in allergic respiratory tract diseases. General practice study on the effectiveness and tolerance in children].
Topics: Adolescent; Asthma; Benzhydryl Compounds; Child; Clinical Trials as Topic; Female; Histamine H1 Anta | 1987 |
Effect of an oral H1-receptor antagonist, terfenadine, on antigen-induced asthma.
Topics: Administration, Oral; Adult; Asthma; Benzhydryl Compounds; Clinical Trials as Topic; Dose-Response R | 1986 |
Effects of a cyclo-oxygenase inhibitor, flurbiprofen, and an H1 histamine receptor antagonist, terfenadine, alone and in combination on allergen induced immediate bronchoconstriction in man.
Topics: Adult; Allergens; Asthma; Benzhydryl Compounds; Bronchi; Bronchial Provocation Tests; Drug Combinati | 1987 |
Treatment of bronchial asthma with terfenadine; a randomized controlled trial.
Topics: Adolescent; Adult; Albuterol; Asthma; Benzhydryl Compounds; Child; Clinical Trials as Topic; Double- | 1987 |
24 other studies available for terfenadine and Asthma, Bronchial
Article | Year |
---|---|
Analysis of disease-dependent sedative profiles of H(1)-antihistamines by large-scale surveillance using the visual analog scale.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Asthma; Butyrophenones; Cetirizine; Child; Chlorpheniram | 2008 |
Allergies in India: a study on medication compliance.
Topics: Adolescent; Adult; Anti-Allergic Agents; Asthma; Bronchodilator Agents; Budesonide; Child; Ethanolam | 2009 |
[Effect of fexofenadine--selective antagonist of histamine receptor (H1) on histamine-induced bronchoconstriction].
Topics: Adult; Anti-Allergic Agents; Asthma; Bronchial Provocation Tests; Bronchoconstriction; Dose-Response | 2003 |
Ipratropium, sodium cromoglycate and antihistamines.
Topics: Acetylcholine; Adolescent; Adult; Asthma; Child; Cromolyn Sodium; Histamine H1 Antagonists; Humans; | 1995 |
Effect of terfenadine on human eosinophil and neutrophil chemotactic response and generation of superoxide.
Topics: Adult; Asthma; Calcimycin; Cell Degranulation; Cell Separation; Chemotaxis, Leukocyte; Dose-Response | 1994 |
Allergic bronchial eosinophilia: a therapeutic approach for the selection of potential bronchial anti-inflammatory drugs.
Topics: Albuterol; Allergens; Animals; Anti-Inflammatory Agents; Asthma; Bronchial Hyperreactivity; Bronchoa | 1993 |
Effects of a new antiallergic drug, VUF-K-8788, on infiltration of lung parenchyma by eosinophils in guinea pigs and eosinophil-adhesion to human umbilical vein endothelial cells (HUVEC).
Topics: Animals; Anti-Allergic Agents; Asthma; Cell Adhesion; Cell Adhesion Molecules; Cell Line; Edema; End | 2001 |
[Hay fever and asthma. Many of your patients have both].
Topics: Asthma; Histamine H1 Antagonists; Humans; Rhinitis, Allergic, Seasonal; Terfenadine; Treatment Outco | 2002 |
Terfenadine in allergic chronic cough in children.
Topics: Asthma; Child; Chronic Disease; Cough; Female; Humans; Hypersensitivity; Male; Pilot Projects; Terfe | 1992 |
Lack of dose-response effect of terfenadine on resting bronchomotor tone in patients with asthma.
Topics: Adolescent; Adult; Asthma; Benzhydryl Compounds; Bronchi; Dose-Response Relationship, Drug; Female; | 1991 |
[A study on the relationship between histamine receptors and bronchial hyperresponsiveness in asthma].
Topics: Adolescent; Adult; Asthma; Bronchial Hyperreactivity; Female; Humans; Male; Ranitidine; Receptors, H | 1991 |
Antiallergic effects of terfenadine on immediate type hypersensitivity reactions.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adenylyl Cyclases; Anaphylaxis; Animals; Asthma; Benzhydryl Com | 1987 |
The mediator and cellular basis of the allergic response.
Topics: Animals; Asthma; Benzhydryl Compounds; Cromolyn Sodium; Eosinophils; Guinea Pigs; Histamine H1 Antag | 1988 |
Inhibitory effect of terfenadine on mediator release from human blood basophils and eosinophils.
Topics: Adolescent; Adult; Asthma; Basophils; Benzhydryl Compounds; Calcimycin; Eosinophils; Female; Histami | 1989 |
Effect of terfenadine on cold air-induced bronchospasm.
Topics: Air; Asthma; Benzhydryl Compounds; Bronchial Spasm; Cold Temperature; Dose-Response Relationship, Dr | 1989 |
[Optimal use of antihistaminics].
Topics: Astemizole; Asthma; Benzhydryl Compounds; Benzimidazoles; Female; Histamine H1 Antagonists; Humans; | 1989 |
The effect of an increase in inhaled allergen dose after terfenadine on the occurrence and magnitude of the late asthmatic response.
Topics: Administration, Inhalation; Adult; Aged; Allergens; Asthma; Benzhydryl Compounds; Female; Forced Exp | 1989 |
The effect of histamine-H1 receptor antagonism with terfenadine on concentration-related AMP-induced bronchoconstriction in asthma.
Topics: Adult; Asthma; Benzhydryl Compounds; Bronchial Spasm; Cyclic AMP; Double-Blind Method; Female; Force | 1989 |
The European experience with antihistamines in asthma.
Topics: Asthma; Benzhydryl Compounds; Chlorpheniramine; Europe; Forced Expiratory Volume; Histamine H1 Antag | 1989 |
Bronchodilator action of the anti-histaminic terfenadine.
Topics: Adult; Albuterol; Asthma; Benzhydryl Compounds; Bronchodilator Agents; Female; Forced Expiratory Vol | 1987 |
Effect of oral terfenadine on the bronchoconstrictor response to inhaled histamine and adenosine 5'-monophosphate in non-atopic asthma.
Topics: Adenosine Monophosphate; Administration, Inhalation; Administration, Oral; Adult; Aged; Asthma; Benz | 1987 |
Effect of terfenadine on the response to exercise and cold air in asthma.
Topics: Adolescent; Adult; Asthma; Asthma, Exercise-Induced; Benzhydryl Compounds; Cold Temperature; Forced | 1988 |
The use of antihistamines for the treatment of airway disease.
Topics: Astemizole; Asthma; Benzhydryl Compounds; Benzimidazoles; Child; Chlorpheniramine; Double-Blind Meth | 1988 |
Pre-treatment with terfenadine.
Topics: Asthma; Asthma, Exercise-Induced; Benzhydryl Compounds; Child; Humans; Terfenadine | 1988 |