terfenadine has been researched along with Anesthesia in 2 studies
Terfenadine: A selective histamine H1-receptor antagonist devoid of central nervous system depressant activity. The drug was used for ALLERGY but withdrawn due to causing LONG QT SYNDROME.
Anesthesia: A state characterized by loss of feeling or sensation. This depression of nerve function is usually the result of pharmacologic action and is induced to allow performance of surgery or other painful procedures.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In order to better understand the variability of pharmacodynamic and pharmacokinetic profiles of terfenadine between the previous studies as well as to qualitatively and quantitatively examine the proarrhythmic potential of its major active metabolite fexofenadine in comparison with that of terfenadine, we directly compared their electropharmacological effects with halothane-anesthetized dogs (n = 3)." | 1.48 | Comparison of electropharmacological effects between terfenadine and its active derivative fexofenadine using a cross-over study in halothane-anesthetized dogs to analyze variability of pharmacodynamic and pharmacokinetic profiles of terfenadine and torsa ( Ando, K; Chiba, K; Goto, A; Hagiwara-Nagasawa, M; Harada, H; Inamura, N; Izumi-Nakaseko, H; Lubna, NJ; Miyamoto, H; Naito, AT; Nakamura, Y; Sugiyama, A; Takagi, K, 2018) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ando, K | 1 |
| Nakamura, Y | 1 |
| Hagiwara-Nagasawa, M | 1 |
| Harada, H | 1 |
| Miyamoto, H | 1 |
| Inamura, N | 1 |
| Takagi, K | 1 |
| Goto, A | 1 |
| Chiba, K | 1 |
| Lubna, NJ | 1 |
| Izumi-Nakaseko, H | 1 |
| Naito, AT | 1 |
| Sugiyama, A | 1 |
| Lu, HR | 1 |
| Remeysen, P | 1 |
| De Clerck, F | 1 |
2 other studies available for terfenadine and Anesthesia
| Article | Year |
|---|---|
Comparison of electropharmacological effects between terfenadine and its active derivative fexofenadine using a cross-over study in halothane-anesthetized dogs to analyze variability of pharmacodynamic and pharmacokinetic profiles of terfenadine and torsa
Topics: Anesthesia; Animals; Arrhythmias, Cardiac; Blood Pressure; Cross-Over Studies; Dogs; Dose-Response R | 2018 |
Nonselective I(Kr)-blockers do not induce torsades de pointes in the anesthetized rabbit during alpha1-adrenoceptor stimulation.
Topics: Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-Agonists; Anesthesia; Animals; Anti-Arrhythmi | 2000 |