terfenadine has been researched along with Allergic Conjunctivitis in 23 studies
Terfenadine: A selective histamine H1-receptor antagonist devoid of central nervous system depressant activity. The drug was used for ALLERGY but withdrawn due to causing LONG QT SYNDROME.
| Excerpt | Relevance | Reference |
|---|---|---|
| "This double-masked, comparative, multicenter study was conducted to assess the onset of action and tolerability of nedocromil sodium 2% ophthalmic solution BID, 60-mg terfenadine tablets BID, and placebo in the treatment of seasonal allergic conjunctivitis." | 9.09 | Comparison of topical nedocromil sodium and oral terfenadine for the treatment of seasonal allergic conjunctivitis. ( Alexander, M; Rosen, LJ; Yang, WH, 1999) |
| "A multicentre, group comparative open study was carried out on 68 patients to compare the effects of 2% sodium cromoglycate eyedrops and an oral antihistamine, terfenadine, on acute symptoms of seasonal allergic conjunctivitis." | 9.07 | The effect of sodium cromoglycate eyedrops compared to the effect of terfenadine on acute symptoms of seasonal allergic conjunctivitis. ( Carlson, C; Kilkku, O; Kumpulainen, T; Kyrönpalo-Kauppinen, S; Laaka, V; Leino, M; Norio, M; Valtola, J, 1992) |
| ") to be more effective overall than the regimen containing the highest fexo-fenadine dosage (with nedocromil as rescue only)." | 6.71 | Supplementation of fexofenadine therapy with nedocromil sodium 2% ophthalmic solution to treat ocular symptoms of seasonal allergic conjunctivitis. ( Alexander, M; Allegro, S; Hicks, A; Patel, P, 2003) |
| "This double-masked, comparative, multicenter study was conducted to assess the onset of action and tolerability of nedocromil sodium 2% ophthalmic solution BID, 60-mg terfenadine tablets BID, and placebo in the treatment of seasonal allergic conjunctivitis." | 5.09 | Comparison of topical nedocromil sodium and oral terfenadine for the treatment of seasonal allergic conjunctivitis. ( Alexander, M; Rosen, LJ; Yang, WH, 1999) |
| "A multicentre, group comparative open study was carried out on 68 patients to compare the effects of 2% sodium cromoglycate eyedrops and an oral antihistamine, terfenadine, on acute symptoms of seasonal allergic conjunctivitis." | 5.07 | The effect of sodium cromoglycate eyedrops compared to the effect of terfenadine on acute symptoms of seasonal allergic conjunctivitis. ( Carlson, C; Kilkku, O; Kumpulainen, T; Kyrönpalo-Kauppinen, S; Laaka, V; Leino, M; Norio, M; Valtola, J, 1992) |
| "Levocabastine is a newly synthesized histamine H1 antagonist which has been formulated as both eye drops and nasal spray." | 3.77 | New trends in the treatment of allergic conjunctivitis. ( Blockhuys, S; Janssens, M; Parys, W, 1992) |
| ") to be more effective overall than the regimen containing the highest fexo-fenadine dosage (with nedocromil as rescue only)." | 2.71 | Supplementation of fexofenadine therapy with nedocromil sodium 2% ophthalmic solution to treat ocular symptoms of seasonal allergic conjunctivitis. ( Alexander, M; Allegro, S; Hicks, A; Patel, P, 2003) |
| "Mizolastine was associated with early phase reduction of: i) clinical symptoms (p < 0." | 2.71 | Mizolastine and fexofenadine modulate cytokine pattern after nasal allergen challenge. ( Ciprandi, G; Cirillo, I; Vizzaccaro, A, 2004) |
| " Evaluation criteria were: (a) clinical: signs and symptoms (recorded daily in a diary card by patients); (b) cytological: inflammatory cell count (neutrophils, eosinophils, metachromatic cells) from nasal lavage at T0 and T7; (c) immunocytochemical: ICAM-1/CD54 expression on nasal epithelial cells at T0 and T7; and (d) mediators dosage (ECP-MPO) on nasal lavage at T0 and T7." | 2.68 | Terfenadine exerts antiallergic activity reducing ICAM-1 expression on nasal epithelial cells in patients with pollen allergy. ( Canonica, GW; Ciprandi, G; Del Giacco, GS; Pronzato, C; Ricca, V; Varese, P, 1995) |
| "Levocabastine is a very potent histamine H1 antagonist, available for ocular use as eye drops containing 0." | 2.67 | Tolerability of levocabastine eye drops. ( Blockhuys, S; Janssens, M, 1993) |
| "Levocabastine was significantly more effective than terfenadine in relieving ocular itching (p = ." | 2.67 | Safety and efficacy of topical levocabastine compared with oral terfenadine. ( Bahmer, FA; Ruprecht, KW, 1994) |
| "Levocabastine was significantly more effective than terfenadine in relieving sneezing, rhinorrhea, lacrimation, itch, and burning sensation (p < 0." | 2.67 | Topical levocabastine compared with orally administered terfenadine for the prophylaxis and treatment of seasonal rhinoconjunctivitis. ( Freng, BA; Garud, O; Korsrud, FR; Kramer, J; Olsen, AK; Poppe, S; Rebo, R; Søhoel, P; Woxen, OJ, 1993) |
| "Pre-treatment with terfenadine resulted in a significantly higher allergen threshold dose than placebo (p less than 0." | 2.67 | Protective effect of different doses of terfenadine on the conjunctival provocation test. ( Buscaglia, S; Canonica, GW; Ciprandi, G; Iudice, A, 1992) |
| " Recommended dosage of loratadine (CAS 79794-75-5) is 10 mg once daily, whereas terfenadine (CAS 50679-08-8) until recently has been recommended as 60 mg twice daily." | 2.67 | Comparison of loratadine and terfenadine in allergic seasonal rhinoconjunctivitis with emphasis on nasal stuffiness and peak flow. ( Hindberg Rasmussen, W; Høi, L; Lorentzen, KA; Nüchel Petersen, L; Olsen, OT; Svendsen, UG, 1992) |
| "The long QT syndrome is a rare disease." | 1.33 | Long QT syndrome in a patient with allergic rhinoconjunctivitis and auto-immune diabetes: focus on the choice of anti-H1 drugs. ( Codreanu, A; de Chillou, C; Moneret-Vautrin, DA, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (13.04) | 18.7374 |
| 1990's | 14 (60.87) | 18.2507 |
| 2000's | 5 (21.74) | 29.6817 |
| 2010's | 1 (4.35) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Andoh, T | 1 |
| Sakai, K | 1 |
| Urashima, M | 1 |
| Kitazawa, K | 1 |
| Honma, A | 1 |
| Kuraishi, Y | 1 |
| Lanier, BQ | 1 |
| Abelson, MB | 2 |
| Berger, WE | 1 |
| Granet, DB | 1 |
| D'Arienzo, PA | 1 |
| Spangler, DL | 2 |
| Kägi, MK | 1 |
| Alexander, M | 2 |
| Patel, P | 1 |
| Allegro, S | 1 |
| Hicks, A | 1 |
| Ober, A | 1 |
| Gotnes, PJ | 1 |
| Ciprandi, G | 3 |
| Cirillo, I | 1 |
| Vizzaccaro, A | 1 |
| Moneret-Vautrin, DA | 1 |
| de Chillou, C | 1 |
| Codreanu, A | 1 |
| Obel, AO | 1 |
| Bahmer, FA | 2 |
| Janssens, M | 2 |
| Blockhuys, S | 2 |
| Ruprecht, KW | 1 |
| Sabbah, A | 2 |
| Hassoun, S | 2 |
| Le Sellin, J | 1 |
| André, C | 2 |
| Sicard, H | 2 |
| Søhoel, P | 1 |
| Freng, BA | 1 |
| Kramer, J | 1 |
| Poppe, S | 1 |
| Rebo, R | 1 |
| Korsrud, FR | 1 |
| Garud, O | 1 |
| Woxen, OJ | 1 |
| Olsen, AK | 1 |
| Lesellin, J | 1 |
| Pronzato, C | 1 |
| Ricca, V | 1 |
| Varese, P | 1 |
| Del Giacco, GS | 1 |
| Canonica, GW | 2 |
| Rosen, LJ | 1 |
| Yang, WH | 1 |
| Parys, W | 1 |
| Wood, SF | 1 |
| Buscaglia, S | 1 |
| Iudice, A | 1 |
| Olsen, OT | 1 |
| Nüchel Petersen, L | 1 |
| Høi, L | 1 |
| Lorentzen, KA | 1 |
| Hindberg Rasmussen, W | 1 |
| Svendsen, UG | 1 |
| Leino, M | 1 |
| Carlson, C | 1 |
| Kilkku, O | 1 |
| Kumpulainen, T | 1 |
| Kyrönpalo-Kauppinen, S | 1 |
| Laaka, V | 1 |
| Norio, M | 1 |
| Valtola, J | 1 |
| Kjellman, NI | 1 |
| Andersson, B | 1 |
| Juniper, EF | 1 |
| White, J | 1 |
| Dolovich, J | 1 |
3 reviews available for terfenadine and Allergic Conjunctivitis
| Article | Year |
|---|---|
Topical levocabastine--an effective alternative to oral antihistamines in seasonal allergic rhinoconjunctivitis.
Topics: Administration, Oral; Administration, Topical; Clinical Trials as Topic; Conjunctivitis, Allergic; D | 1995 |
New trends in the treatment of allergic conjunctivitis.
Topics: Animals; Antazoline; Conjunctivitis, Allergic; Cromolyn Sodium; Histamine H1 Antagonists; Humans; Na | 1992 |
Clinical experience with non-sedating antihistamines in paediatric allergic rhinitis.
Topics: Adolescent; Astemizole; Asthma; Child; Child, Preschool; Chlorpheniramine; Clinical Trials as Topic; | 1992 |
18 trials available for terfenadine and Allergic Conjunctivitis
| Article | Year |
|---|---|
Comparison of the efficacy of combined fluticasone propionate and olopatadine versus combined fluticasone propionate and fexofenadine for the treatment of allergic rhinoconjunctivitis induced by conjunctival allergen challenge.
Topics: Administration, Intranasal; Administration, Topical; Adult; Allergens; Androstadienes; Anti-Allergic | 2002 |
Supplementation of fexofenadine therapy with nedocromil sodium 2% ophthalmic solution to treat ocular symptoms of seasonal allergic conjunctivitis.
Topics: Adolescent; Adult; Ambrosia; Anti-Allergic Agents; Child; Conjunctivitis, Allergic; Drug Therapy, Co | 2003 |
Randomized, double-masked comparison of olopatadine ophthalmic solution, mometasone furoate monohydrate nasal spray, and fexofenadine hydrochloride tablets using the conjunctival and nasal allergen challenge models.
Topics: Administration, Intranasal; Administration, Oral; Administration, Topical; Adult; Aged; Allergens; A | 2003 |
Mizolastine and fexofenadine modulate cytokine pattern after nasal allergen challenge.
Topics: Adult; Allergens; Anti-Allergic Agents; Benzimidazoles; Conjunctivitis, Allergic; Cytokines; Double- | 2004 |
A comparison of topical levocabastine and oral terfenadine in the treatment of allergic rhinoconjunctivitis. The Livostin Study Group.
Topics: Administration, Intranasal; Administration, Oral; Adult; Conjunctivitis, Allergic; Double-Blind Meth | 1993 |
Tolerability of levocabastine eye drops.
Topics: Adolescent; Adult; Conjunctivitis, Allergic; Double-Blind Method; Drug Administration Schedule; Drug | 1993 |
Safety and efficacy of topical levocabastine compared with oral terfenadine.
Topics: Administration, Oral; Administration, Topical; Adult; Conjunctivitis, Allergic; Double-Blind Method; | 1994 |
A double-blind, placebo-controlled trial by the sublingual route of immunotherapy with a standardized grass pollen extract.
Topics: Administration, Sublingual; Adolescent; Adult; Aerosols; Betamethasone; Chlorpheniramine; Combined M | 1994 |
Topical levocabastine compared with orally administered terfenadine for the prophylaxis and treatment of seasonal rhinoconjunctivitis.
Topics: Administration, Oral; Adult; Aerosols; Conjunctivitis, Allergic; Double-Blind Method; Drug Tolerance | 1993 |
[Sublingual specific immunotherapy for rhinoconjunctivitis caused by grass pollens].
Topics: Administration, Sublingual; Adolescent; Adult; Allergens; Betamethasone; Chlorpheniramine; Combined | 1993 |
Terfenadine exerts antiallergic activity reducing ICAM-1 expression on nasal epithelial cells in patients with pollen allergy.
Topics: Adolescent; Adult; Anti-Allergic Agents; Cell Communication; Conjunctivitis, Allergic; Double-Blind | 1995 |
Comparison of topical nedocromil sodium and oral terfenadine for the treatment of seasonal allergic conjunctivitis.
Topics: Administration, Oral; Adolescent; Adult; Aged; Anti-Inflammatory Agents; Child; Conjunctivitis, Alle | 1999 |
New trends in the treatment of allergic conjunctivitis.
Topics: Animals; Antazoline; Conjunctivitis, Allergic; Cromolyn Sodium; Histamine H1 Antagonists; Humans; Na | 1992 |
Protective effect of different doses of terfenadine on the conjunctival provocation test.
Topics: Adolescent; Adult; Allergens; Cell Count; Conjunctiva; Conjunctivitis, Allergic; Female; Humans; Mal | 1992 |
Comparison of loratadine and terfenadine in allergic seasonal rhinoconjunctivitis with emphasis on nasal stuffiness and peak flow.
Topics: Adolescent; Adult; Aged; Conjunctivitis, Allergic; Double-Blind Method; Female; Humans; Loratadine; | 1992 |
The effect of sodium cromoglycate eyedrops compared to the effect of terfenadine on acute symptoms of seasonal allergic conjunctivitis.
Topics: Acute Disease; Administration, Oral; Administration, Topical; Adolescent; Adult; Aged; Child; Conjun | 1992 |
Terfenadine reduces skin and conjunctival reactivity in grass pollen allergic children.
Topics: Benzhydryl Compounds; Child; Clinical Trials as Topic; Conjunctiva; Conjunctivitis, Allergic; Double | 1986 |
Efficacy of continuous treatment with astemizole (Hismanal) and terfenadine (Seldane) in ragweed pollen-induced rhinoconjunctivitis.
Topics: Adult; Allergens; Astemizole; Benzhydryl Compounds; Benzimidazoles; Conjunctivitis, Allergic; Drug T | 1988 |
3 other studies available for terfenadine and Allergic Conjunctivitis
| Article | Year |
|---|---|
Involvement of leukotriene B4 in itching in a mouse model of ocular allergy.
Topics: Allergens; Ambrosia; Animals; Conjunctivitis, Allergic; Disease Models, Animal; Glucocorticoids; His | 2012 |
Long QT syndrome in a patient with allergic rhinoconjunctivitis and auto-immune diabetes: focus on the choice of anti-H1 drugs.
Topics: Adolescent; Adrenergic beta-Antagonists; Anti-Asthmatic Agents; Butyrophenones; Cetirizine; Conjunct | 2006 |
Practical therapeutics: the use of histamine receptor antagonists in contemporary times.
Topics: Astemizole; Benzhydryl Compounds; Benzimidazoles; Child; Cimetidine; Conjunctivitis, Allergic; Hista | 1984 |