terfenadine has been researched along with Air Sickness in 3 studies
Terfenadine: A selective histamine H1-receptor antagonist devoid of central nervous system depressant activity. The drug was used for ALLERGY but withdrawn due to causing LONG QT SYNDROME.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The failure of the second-generation antihistamines cetirizine and fexofenadine to prevent motion sickness suggests that the therapeutic actions of this class of antihistamines against motion sickness may be mediated through central versus peripheral receptors." | 9.10 | Failure of cetirizine and fexofenadine to prevent motion sickness. ( Cheung, BS; Heskin, R; Hofer, KD, 2003) |
| "Terfenadine (Seldane) was administered to 14 male subjects in a randomized, double-blinded, and crossed-over design to assess the efficacy of this peripherally active antihistamine as an anti-motion sickness drug." | 9.07 | Control of nausea and autonomic dysfunction with terfenadine, a peripherally acting antihistamine. ( Calkins, DS; Kohl, RL; Robinson, RE, 1991) |
| "The failure of the second-generation antihistamines cetirizine and fexofenadine to prevent motion sickness suggests that the therapeutic actions of this class of antihistamines against motion sickness may be mediated through central versus peripheral receptors." | 5.10 | Failure of cetirizine and fexofenadine to prevent motion sickness. ( Cheung, BS; Heskin, R; Hofer, KD, 2003) |
| "Terfenadine (Seldane) was administered to 14 male subjects in a randomized, double-blinded, and crossed-over design to assess the efficacy of this peripherally active antihistamine as an anti-motion sickness drug." | 5.07 | Control of nausea and autonomic dysfunction with terfenadine, a peripherally acting antihistamine. ( Calkins, DS; Kohl, RL; Robinson, RE, 1991) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (66.67) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cheung, BS | 1 |
| Heskin, R | 1 |
| Hofer, KD | 1 |
| Kohl, RL | 2 |
| Calkins, DS | 1 |
| Robinson, RE | 1 |
3 trials available for terfenadine and Air Sickness
| Article | Year |
|---|---|
Failure of cetirizine and fexofenadine to prevent motion sickness.
Topics: Adult; Analysis of Variance; Cetirizine; Cross-Over Studies; Double-Blind Method; Female; Humans; Ma | 2003 |
Is there a role for nonsedating antihistamines in motion sickness? Fallout from space research may soon benefit your patients.
Topics: Aerospace Medicine; Astemizole; Coriolis Force; Doxepin; Drug Evaluation; Head Movements; Histamine | 1991 |
Control of nausea and autonomic dysfunction with terfenadine, a peripherally acting antihistamine.
Topics: Autonomic Nervous System; Benzhydryl Compounds; Double-Blind Method; Histamine H1 Antagonists; Human | 1991 |