terfenadine has been researched along with Aging in 4 studies
Terfenadine: A selective histamine H1-receptor antagonist devoid of central nervous system depressant activity. The drug was used for ALLERGY but withdrawn due to causing LONG QT SYNDROME.
Aging: The gradual irreversible changes in structure and function of an organism that occur as a result of the passage of time.
| Excerpt | Relevance | Reference |
|---|---|---|
| " We conclude that the cause of the increased oral clearance of fexofenadine is a reduced bioavailability caused by induction of intestinal P-glycoprotein." | 2.70 | The effect of rifampin administration on the disposition of fexofenadine. ( Bruce, MA; Haehner-Daniels, BD; Hall, SD; Hamman, MA, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (25.00) | 18.7374 |
| 1990's | 2 (50.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Melillo, G | 1 |
| D'Amato, G | 1 |
| Zanussi, C | 1 |
| Ortolani, C | 1 |
| Pastorello, E | 1 |
| Loy, M | 1 |
| Di Tucci, A | 1 |
| Locci, F | 1 |
| Del Giacco, GS | 1 |
| Lenzini, L | 1 |
| Sestini, P | 1 |
| Rottoli, P | 1 |
| Philpot, E | 1 |
| Hamman, MA | 1 |
| Bruce, MA | 1 |
| Haehner-Daniels, BD | 1 |
| Hall, SD | 1 |
| Simons, KJ | 1 |
| Martin, TJ | 1 |
| Watson, WT | 1 |
| Simons, FE | 1 |
3 trials available for terfenadine and Aging
| Article | Year |
|---|---|
A multicentre controlled trial of terfenadine, dexchlorpheniramine, and placebo in allergic rhinitis.
Topics: Adolescent; Adult; Aging; Benzhydryl Compounds; Chlorpheniramine; Clinical Trials as Topic; Double-B | 1982 |
The effect of rifampin administration on the disposition of fexofenadine.
Topics: Administration, Oral; Adult; Aged; Aging; Analysis of Variance; ATP Binding Cassette Transporter, Su | 2001 |
Pharmacokinetics and pharmacodynamics of terfenadine and chlorpheniramine in the elderly.
Topics: Aged; Aging; Benzhydryl Compounds; Chlorpheniramine; Chromatography, High Pressure Liquid; Double-Bl | 1990 |
1 other study available for terfenadine and Aging
| Article | Year |
|---|---|
Reply to Gonzalez and Estes.
Topics: Adult; Aged; Aging; Histamine H1 Antagonists; Humans; Terfenadine | 1999 |