Page last updated: 2024-11-04

terbutaline and Heart Failure

terbutaline has been researched along with Heart Failure in 21 studies

Terbutaline: A selective beta-2 adrenergic agonist used as a bronchodilator and tocolytic.
terbutaline : A member of the class of phenylethanolamines that is catechol substituted at position 5 by a 2-(tert-butylamino)-1-hydroxyethyl group.

Heart Failure: A heterogeneous condition in which the heart is unable to pump out sufficient blood to meet the metabolic need of the body. Heart failure can be caused by structural defects, functional abnormalities (VENTRICULAR DYSFUNCTION), or a sudden overload beyond its capacity. Chronic heart failure is more common than acute heart failure which results from sudden insult to cardiac function, such as MYOCARDIAL INFARCTION.

Research Excerpts

ExcerptRelevanceReference
"To determine whether metoprolol succinate (a beta(1)-selective beta-blocker) remains beta(1)-selective compared with carvedilol (a nonselective beta-blocker) during upward titration of doses in patients with American College of Cardiology (ACC) stage C heart failure."9.14Beta-receptor selectivity of carvedilol and metoprolol succinate in patients with heart failure (SELECT trial): a randomized dose-ranging trial. ( Gilbert, EM; Lombardi, WL; Macgregor, J; Munger, M; Stoddard, GP; Zebrack, JS, 2009)
"To describe the replacement of intravenous dopamine with oral terbutaline in a patient with American College of Cardiology/American Heart Association stage D heart failure (HF)."7.79Oral terbutaline in replacement for intravenous dopamine in a patient with end-stage heart failure. ( Cheng, JW; Miles, A; Shulan, A, 2013)
"The hemodynamic effects of captopril (CPT) alone and in combination with the beta-adrenergic receptor agonist terbutaline (TBT) were evaluated in 10 patients with severe chronic congestive heart failure (CHF)."7.66Complementary combined captopril and terbutaline therapy in severe chronic congestive heart failure. ( Amsterdam, EA; Awan, NA; Lui, H; Mason, DT; Needham, KE; Rutledge, J, 1982)
"To determine whether metoprolol succinate (a beta(1)-selective beta-blocker) remains beta(1)-selective compared with carvedilol (a nonselective beta-blocker) during upward titration of doses in patients with American College of Cardiology (ACC) stage C heart failure."5.14Beta-receptor selectivity of carvedilol and metoprolol succinate in patients with heart failure (SELECT trial): a randomized dose-ranging trial. ( Gilbert, EM; Lombardi, WL; Macgregor, J; Munger, M; Stoddard, GP; Zebrack, JS, 2009)
"To describe the replacement of intravenous dopamine with oral terbutaline in a patient with American College of Cardiology/American Heart Association stage D heart failure (HF)."3.79Oral terbutaline in replacement for intravenous dopamine in a patient with end-stage heart failure. ( Cheng, JW; Miles, A; Shulan, A, 2013)
" To control hypertension and chronic heart failure he had been treated with 5 mg ramipril and 12."3.73[A patient with severe hyperkalaemia -- an emergency after RALES]. ( Daul, A; Nürnberger, J; Philipp, T, 2005)
" We initiated maternal administration of a sympathomimetic, specifically terbutaline, to prevent fetal heart failure."3.71Treatment of fetal congenital complete heart block with maternal administration of beta-sympathomimetics (terbutaline): a case report. ( Hirahara, F; Iwamoto, M; Sakakibara, H; Sato, K; Shigeta, H; Yoshida, H, 2001)
"Four cases are presented of maternal pulmonary edema occurring in patients who had no primary cardiac disease but who were receiving terbutaline and glucocorticoids or terbutaline alone for treatment of premature labor."3.66Maternal pulmonary edema resulting from betamimetic and glucocorticoid therapy. ( Arias, F; Jacobs, MM; Knight, AB, 1980)
"The hemodynamic effects of captopril (CPT) alone and in combination with the beta-adrenergic receptor agonist terbutaline (TBT) were evaluated in 10 patients with severe chronic congestive heart failure (CHF)."3.66Complementary combined captopril and terbutaline therapy in severe chronic congestive heart failure. ( Amsterdam, EA; Awan, NA; Lui, H; Mason, DT; Needham, KE; Rutledge, J, 1982)
"Terbutaline was added to the instillate to determine whether heart failure rats responded to beta-adrenoceptor stimulation."1.35Beta-adrenoceptor stimulation of alveolar fluid clearance is increased in rats with heart failure. ( Folkesson, HG; Horne, WI; Koshy, S; Li, T; Luther, DJ; Maron, MB; Meszaros, JG; Ohanyan, V; Pilati, CF; Walro, JM, 2009)
" The beta(2)AR polymorphism significantly affected the dose-response curves for terbutaline-induced inotropic and chronotropic responses: compared with WT individuals, subjects with the Thr164Ile receptor had substantial blunting in maximal increases in heart rate (WT, 29."1.31Blunted cardiac responses to receptor activation in subjects with Thr164Ile beta(2)-adrenoceptors. ( Brodde, OE; Büscher, R; Dhein, S; Insel, PA; Radke, J; Tellkamp, R, 2001)

Research

Studies (21)

TimeframeStudies, this research(%)All Research%
pre-19907 (33.33)18.7374
1990's5 (23.81)18.2507
2000's7 (33.33)29.6817
2010's2 (9.52)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Miles, A1
Shulan, A1
Cheng, JW1
Maron, MB1
Luther, DJ1
Pilati, CF1
Ohanyan, V1
Li, T1
Koshy, S1
Horne, WI1
Meszaros, JG1
Walro, JM1
Folkesson, HG1
Zebrack, JS1
Munger, M1
Macgregor, J1
Lombardi, WL1
Stoddard, GP1
Gilbert, EM1
Cuneo, BF1
Lee, M1
Roberson, D1
Niksch, A1
Ovadia, M1
Parilla, BV1
Benson, DW1
Tsurikisawa, N1
Taniguchi, M1
Suzuki, S1
Akiyama, K1
Nürnberger, J1
Daul, A1
Philipp, T1
Brodde, OE2
Bruck, H1
Leineweber, K1
Jacobs, MM1
Knight, AB1
Arias, F1
Bijak, A1
Czołpiński, T1
Carpenter, RJ1
Decuir, P1
Awan, NA1
Needham, KE1
Lui, H1
Rutledge, J1
Amsterdam, EA1
Mason, DT1
Wang, RY1
Tse, TF1
Yu, DY1
Lee, PK1
Sum, MS1
Chow, MS1
Slutsky, R1
Jenne, JW1
Lindmark, B1
Ottosson, A1
Büscher, R1
Tellkamp, R1
Radke, J1
Dhein, S1
Insel, PA2
Yoshida, H1
Iwamoto, M1
Sakakibara, H1
Shigeta, H1
Hirahara, F1
Sato, K1
Takahashi, M1
Shichiri, G1
Amano, M1
Kanamori, T1
Kinoshita, M1
Maisel, AS2
Knowlton, KU1
Fowler, P1
Rearden, A1
Ziegler, MG1
Motulsky, HJ1
Michel, MC2
Aksel'rud, MM1
Ustinov, AG1
Tatarskiĭ, AR1
Godiaev, MIa1
Zasimov, AA1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Heart Sounds at Home: Prospective Maternal Surveillance of SSA Positive Pregnancies Using a Hand-Held Fetal Heart Rate Monitor[NCT02920346]700 participants (Anticipated)Observational2014-03-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

2 reviews available for terbutaline and Heart Failure

ArticleYear
Cardiac adrenoceptors: physiological and pathophysiological relevance.
    Journal of pharmacological sciences, 2006, Volume: 100, Issue:5

    Topics: Adrenergic beta-1 Receptor Agonists; Adrenergic beta-2 Receptor Agonists; Cyclic AMP-Dependent Prote

2006
[New drugs with positive inotropic action].
    Kardiologia polska, 1982, Volume: 25, Issue:4

    Topics: Adrenergic beta-Agonists; Albuterol; Aminopyridines; Amrinone; Cardiotonic Agents; Chronic Disease;

1982

Trials

1 trial available for terbutaline and Heart Failure

ArticleYear
Beta-receptor selectivity of carvedilol and metoprolol succinate in patients with heart failure (SELECT trial): a randomized dose-ranging trial.
    Pharmacotherapy, 2009, Volume: 29, Issue:8

    Topics: Adrenergic beta-1 Receptor Antagonists; Adrenergic beta-2 Receptor Antagonists; Adrenergic beta-Agon

2009

Other Studies

18 other studies available for terbutaline and Heart Failure

ArticleYear
Oral terbutaline in replacement for intravenous dopamine in a patient with end-stage heart failure.
    The Annals of pharmacotherapy, 2013, Volume: 47, Issue:4

    Topics: Adrenergic beta-2 Receptor Agonists; Cardiotonic Agents; Dopamine; Heart Failure; Humans; Male; Midd

2013
Beta-adrenoceptor stimulation of alveolar fluid clearance is increased in rats with heart failure.
    American journal of physiology. Lung cellular and molecular physiology, 2009, Volume: 297, Issue:3

    Topics: Animals; Body Fluids; Epithelial Cells; Gene Expression Regulation; Heart Failure; Hormones; Hyperpl

2009
A management strategy for fetal immune-mediated atrioventricular block.
    The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians, 2010, Volume: 23, Issue:12

    Topics: Atrioventricular Block; Cardiotonic Agents; Cesarean Section; Dexamethasone; Digoxin; Female; Fetal

2010
Effects of a nitro compound patch on neuropathy in Churg-Strauss syndrome.
    Allergy, 2003, Volume: 58, Issue:7

    Topics: Adrenergic beta-Agonists; Asthma; Churg-Strauss Syndrome; Cyclophosphamide; Drug Hypersensitivity; F

2003
[A patient with severe hyperkalaemia -- an emergency after RALES].
    Deutsche medizinische Wochenschrift (1946), 2005, Sep-09, Volume: 130, Issue:36

    Topics: Acute Kidney Injury; Adrenergic beta-Agonists; Angiotensin II Type 1 Receptor Blockers; Angiotensin-

2005
Maternal pulmonary edema resulting from betamimetic and glucocorticoid therapy.
    Obstetrics and gynecology, 1980, Volume: 56, Issue:1

    Topics: Adolescent; Adrenergic beta-Agonists; Adult; Cardiac Output; Drug Therapy, Combination; Female; Gluc

1980
Cardiovascular collapse associated with oral terbutaline tocolytic therapy.
    American journal of obstetrics and gynecology, 1984, Mar-15, Volume: 148, Issue:6

    Topics: Administration, Oral; Adult; Electrocardiography; Female; Heart Failure; Humans; Obstetric Labor, Pr

1984
Complementary combined captopril and terbutaline therapy in severe chronic congestive heart failure.
    American heart journal, 1982, Volume: 104, Issue:5 Pt 2

    Topics: Adult; Aged; Captopril; Cardiac Catheterization; Drug Therapy, Combination; Female; Heart Failure; H

1982
Beneficial hemodynamic effects of intravenous terbutaline in patients with severe heart failure.
    American heart journal, 1982, Volume: 104, Issue:5 Pt 1

    Topics: Adult; Aged; Blood Pressure; Cardiac Output; Female; Heart Failure; Heart Rate; Hemodynamics; Humans

1982
Hemodynamic effects of inhaled terbutaline in congestive heart failure patients without lung disease: beneficial cardiotonic and vasodilator beta-agonist properties evaluated by ventricular catheterization and radionuclide angiography.
    American heart journal, 1981, Volume: 101, Issue:5

    Topics: Cardiac Catheterization; Cardiac Output; Cardiac Volume; Heart; Heart Failure; Hemodynamics; Humans;

1981
Can oral beta2 agonists cause heart failure?
    Lancet (London, England), 1998, Oct-03, Volume: 352, Issue:9134

    Topics: Administration, Oral; Adrenergic beta-Agonists; Aged; Albuterol; Asthma; Bronchodilator Agents; Coho

1998
Beta2 agonists and heart failure.
    Lancet (London, England), 1998, Nov-21, Volume: 352, Issue:9141

    Topics: Adrenergic beta-2 Receptor Agonists; Adrenergic beta-Agonists; Albuterol; Evidence-Based Medicine; H

1998
Blunted cardiac responses to receptor activation in subjects with Thr164Ile beta(2)-adrenoceptors.
    Circulation, 2001, Feb-27, Volume: 103, Issue:8

    Topics: Adrenergic beta-Agonists; Adult; Amino Acid Substitution; Female; Genetic Testing; Genotype; Heart F

2001
Treatment of fetal congenital complete heart block with maternal administration of beta-sympathomimetics (terbutaline): a case report.
    Gynecologic and obstetric investigation, 2001, Volume: 52, Issue:2

    Topics: Adult; Cardiotocography; Female; Fetal Diseases; Fetal Heart; Heart Block; Heart Failure; Heart Rate

2001
Increased uncoupling of beta-, beta 1- and beta 2-adrenoceptor to myocardial contraction in failing human myocardium.
    Japanese circulation journal, 1992, Volume: 56, Issue:7

    Topics: Adult; Aged; Binding, Competitive; Dobutamine; Down-Regulation; Female; Heart Failure; Humans; Iodoc

1992
Adrenergic control of circulating lymphocyte subpopulations. Effects of congestive heart failure, dynamic exercise, and terbutaline treatment.
    The Journal of clinical investigation, 1990, Volume: 85, Issue:2

    Topics: Adult; Aged; Heart Failure; Humans; Leukocyte Count; Lymphocytes; Male; Middle Aged; Physical Exerti

1990
Beta-adrenoceptor control of immune function in congestive heart failure.
    British journal of clinical pharmacology, 1990, Volume: 30 Suppl 1

    Topics: Adenylyl Cyclases; Adult; Aged; Cyclic AMP; Female; Heart Failure; Humans; Isoproterenol; Lymphocyte

1990
[Use of terbutaline in patients with myocardial infarct and concomitant chronic obstructive diseases of the lungs].
    Sovetskaia meditsina, 1988, Issue:3

    Topics: Administration, Inhalation; Cardiac Catheterization; Drug Evaluation; Heart Failure; Hemodynamics; H

1988