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terbutaline and Cystic Fibrosis

terbutaline has been researched along with Cystic Fibrosis in 13 studies

Terbutaline: A selective beta-2 adrenergic agonist used as a bronchodilator and tocolytic.
terbutaline : A member of the class of phenylethanolamines that is catechol substituted at position 5 by a 2-(tert-butylamino)-1-hydroxyethyl group.

Cystic Fibrosis: An autosomal recessive genetic disease of the EXOCRINE GLANDS. It is caused by mutations in the gene encoding the CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR expressed in several organs including the LUNG, the PANCREAS, the BILIARY SYSTEM, and the SWEAT GLANDS. Cystic fibrosis is characterized by epithelial secretory dysfunction associated with ductal obstruction resulting in AIRWAY OBSTRUCTION; chronic RESPIRATORY INFECTIONS; PANCREATIC INSUFFICIENCY; maldigestion; salt depletion; and HEAT PROSTRATION.

Research Excerpts

ExcerptRelevanceReference
"Twenty three patients completed a double-blind study, comparing intravenous and nebulized terbutaline, during the first four days of a pulmonary exacerbation of cystic fibrosis (CF), with follow-up to day 10."9.07Comparison of nebulized and intravenous terbutaline during exacerbations of pulmonary infection in patients with cystic fibrosis. ( Finnegan, MJ; Hodson, ME; Hughes, DV, 1992)
"Atopy and bronchial responsiveness to histamine, exercise and bronchodilators were investigated in 18 adult patients with cystic fibrosis (CF)."7.68Bronchial vagal tone and responsiveness to histamine, exercise and bronchodilators in adult patients with cystic fibrosis. ( Festen, J; Lammers, JW; van Haren, EH; van Herwaarden, CL, 1992)
"Twenty three patients completed a double-blind study, comparing intravenous and nebulized terbutaline, during the first four days of a pulmonary exacerbation of cystic fibrosis (CF), with follow-up to day 10."5.07Comparison of nebulized and intravenous terbutaline during exacerbations of pulmonary infection in patients with cystic fibrosis. ( Finnegan, MJ; Hodson, ME; Hughes, DV, 1992)
"The airway response to exercise and inhaled terbutaline was assessed in 25 patients with cystic fibrosis (CF), seeking evidence for the possible deleterious effects of bronchial muscle relaxation."5.06Changes in airflow obstruction and oxygen saturation in response to exercise and bronchodilators in cystic fibrosis. ( Heaf, D; Macfarlane, PI, 1990)
"Patients with cystic fibrosis (CF) were investigated for mucociliary clearance (with and without stimulation by terbutaline), clinical picture, ventilatory function and ultrastructure of cilia."5.04Cystic fibrosis compared with the immotile-cilia syndrome. A study of mucociliary clearance, ciliary ultrastructure, clinical picture and ventilatory function. ( Afzelius, BA; Camner, P; Kollberg, H; Mossberg, B; Philipson, K, 1978)
"Atopy and bronchial responsiveness to histamine, exercise and bronchodilators were investigated in 18 adult patients with cystic fibrosis (CF)."3.68Bronchial vagal tone and responsiveness to histamine, exercise and bronchodilators in adult patients with cystic fibrosis. ( Festen, J; Lammers, JW; van Haren, EH; van Herwaarden, CL, 1992)
"Elemental distribution and ultrastructure of the submandibular gland, the parotid gland and the pancreas were investigated in three suggested animal models of the disease cystic fibrosis: the chronically reserpinized rat, the chronically isoproterenol-treated rat, and the chronically pilocarpine-treated rat."3.67X-ray microanalysis of exocrine glands in animal models for cystic fibrosis. ( Müller, RM; Roomans, GM, 1985)

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19904 (30.77)18.7374
1990's9 (69.23)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Götz, M1
Zabner, J2
Couture, LA1
Gregory, RJ1
Graham, SM1
Smith, AE2
Welsh, MJ2
Middleton, PG1
Geddes, DM1
Alton, EW1
Mortensen, J1
Hansen, A1
Falk, M1
Nielsen, IK1
Groth, S1
Duperrex, O1
Berclaz, PY1
Bertrand, D1
Lacroix, JS1
Pochon, N1
Belli, D1
Rochat, T1
Cheng, SH1
Meeker, D1
Launspach, J1
Balfour, R1
Perricone, MA1
Morris, JE1
Marshall, J1
Fasbender, A1
Kollberg, H1
Mossberg, B1
Afzelius, BA1
Philipson, K1
Camner, P1
Wood, RE1
Wanner, A1
Hirsch, J1
Farrell, PM1
van Haren, EH2
Lammers, JW2
Festen, J2
van Herwaarden, CL2
Finnegan, MJ1
Hughes, DV1
Hodson, ME1
Macfarlane, PI1
Heaf, D1
Müller, RM1
Roomans, GM1

Trials

5 trials available for terbutaline and Cystic Fibrosis

ArticleYear
Reduced effect of inhaled beta 2-adrenergic agonists on lung mucociliary clearance in patients with cystic fibrosis.
    Chest, 1993, Volume: 103, Issue:3

    Topics: Administration, Inhalation; Adolescent; Adrenergic beta-Agonists; Aerosols; Analysis of Variance; Ch

1993
Comparison of DNA-lipid complexes and DNA alone for gene transfer to cystic fibrosis airway epithelia in vivo.
    The Journal of clinical investigation, 1997, Sep-15, Volume: 100, Issue:6

    Topics: Adolescent; Adult; Amiloride; Chlorine; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance R

1997
Cystic fibrosis compared with the immotile-cilia syndrome. A study of mucociliary clearance, ciliary ultrastructure, clinical picture and ventilatory function.
    Scandinavian journal of respiratory diseases, 1978, Volume: 59, Issue:6

    Topics: Adult; Bronchi; Bronchial Diseases; Cilia; Clinical Trials as Topic; Cystic Fibrosis; Double-Blind M

1978
Comparison of nebulized and intravenous terbutaline during exacerbations of pulmonary infection in patients with cystic fibrosis.
    The European respiratory journal, 1992, Volume: 5, Issue:9

    Topics: Administration, Intranasal; Adult; Cystic Fibrosis; Double-Blind Method; Female; Humans; Infusions,

1992
Changes in airflow obstruction and oxygen saturation in response to exercise and bronchodilators in cystic fibrosis.
    Pediatric pulmonology, 1990, Volume: 8, Issue:1

    Topics: Adolescent; Adult; Child; Child, Preschool; Cystic Fibrosis; Exercise; Female; Forced Expiratory Vol

1990

Other Studies

8 other studies available for terbutaline and Cystic Fibrosis

ArticleYear
[Obstructive airway diseases in children].
    Wiener medizinische Wochenschrift (1946), 1982, Feb-28, Volume: 132, Issue:4

    Topics: Abscess; Adult; Asthma; Child; Child, Preschool; Cystic Fibrosis; Foreign-Body Reaction; Humans; Inh

1982
Adenovirus-mediated gene transfer transiently corrects the chloride transport defect in nasal epithelia of patients with cystic fibrosis.
    Cell, 1993, Oct-22, Volume: 75, Issue:2

    Topics: Adenoviridae; Adult; Amiloride; Biological Transport; Chlorides; Cystic Fibrosis; Cystic Fibrosis Tr

1993
Protocols for in vivo measurement of the ion transport defects in cystic fibrosis nasal epithelium.
    The European respiratory journal, 1994, Volume: 7, Issue:11

    Topics: Adult; Amiloride; Biological Transport, Active; Chlorides; Cystic Fibrosis; Electric Conductivity; F

1994
A new device for in vivo measurement of nasal transepithelial potential difference in cystic fibrosis patients and normal subjects.
    The European respiratory journal, 1997, Volume: 10, Issue:7

    Topics: Adult; Amiloride; Case-Control Studies; Cystic Fibrosis; Electric Conductivity; Electrodes; Endoscop

1997
Tracheal mucociliary transport in patients with cystic fibrosis and its stimulation by terbutaline.
    The American review of respiratory disease, 1975, Volume: 111, Issue:6

    Topics: Adolescent; Adult; Airway Obstruction; Bronchoscopy; Cilia; Cystic Fibrosis; Female; Humans; Male; M

1975
Bronchial vagal tone and responsiveness to histamine, exercise and bronchodilators in adult patients with cystic fibrosis.
    The European respiratory journal, 1992, Volume: 5, Issue:9

    Topics: Adolescent; Adult; Bronchi; Bronchial Hyperreactivity; Bronchial Provocation Tests; Cystic Fibrosis;

1992
Bronchodilator response in adult patients with cystic fibrosis: effects on large and small airways.
    The European respiratory journal, 1991, Volume: 4, Issue:3

    Topics: Administration, Inhalation; Adolescent; Adult; Airway Resistance; Bronchoconstriction; Cystic Fibros

1991
X-ray microanalysis of exocrine glands in animal models for cystic fibrosis.
    Scanning electron microscopy, 1985, Issue:Pt 4

    Topics: Adrenergic beta-Agonists; Animals; Cystic Fibrosis; Cytoplasmic Granules; Disease Models, Animal; El

1985