Page last updated: 2024-11-04

terbutaline and Bronchiolitis, Viral

terbutaline has been researched along with Bronchiolitis, Viral in 2 studies

Terbutaline: A selective beta-2 adrenergic agonist used as a bronchodilator and tocolytic.
terbutaline : A member of the class of phenylethanolamines that is catechol substituted at position 5 by a 2-(tert-butylamino)-1-hydroxyethyl group.

Bronchiolitis, Viral: An acute inflammatory disease of the lower RESPIRATORY TRACT, caused by paramyxoviruses, occurring primarily in infants and young children; the viruses most commonly implicated are PARAINFLUENZA VIRUS TYPE 3; RESPIRATORY SYNCYTIAL VIRUS, HUMAN; and METAPNEUMOVIRUS.

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19901 (50.00)18.7374
1990's0 (0.00)18.2507
2000's1 (50.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Sarrell, EM1
Tal, G1
Witzling, M1
Someck, E1
Houri, S1
Cohen, HA1
Mandelberg, A1
Müller-Wening, W1
Ruland, F1
Wenner, J1
von der Hardt, H1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Safety and Efficacy of Hypertonic Vrs. Normal Saline as Diluent of Salbutamol to Reduce Respiratory Distress in Outpatients With the Clinical Diagnosis of Bronchiolitis During the RSV Epidemic.[NCT00696540]Phase 274 participants (Anticipated)Interventional2008-06-30Recruiting
Nebulized Hypertonic Saline for Acute Bronchiolitis in the Emergency Department[NCT01247064]Phase 462 participants (Actual)Interventional2010-10-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Oxygen Saturation Change

(NCT01247064)
Timeframe: Baseline and 1 hour

Interventionpercent (Mean)
Nebulized 3% Saline1.1
Nebulized 0.9% Normal Saline0.1

Parental Perception of Improvement of Breathing After Study Medication

(NCT01247064)
Timeframe: 1 hour

Interventionpercentage of participants (Number)
Nebulized 3% Saline50
Nebulized 0.9% Normal Saline54.8

Rate of Hospitalization

(NCT01247064)
Timeframe: 1 day

Interventionpercentage of participants (Number)
Nebulized 3% Saline71
Nebulized 0.9% Normal Saline64.5

Respiratory Assessment Change Score (RACS)

The Respiratory Assessment Change Score (RACS) assesses change in respiratory status using the change in the Respiratory Distress Assessment Instrument (RDAI) and a standardized change in respiratory rate, with points being assigned by change increments of 10%. Thus, a change in respiratory rate of ≤5% from baseline counted as a change of 0 units, decrease/increase of 6% to 15% counted as improvement/deterioration of 1 unit, etc. The overall RACS is the arithmetic sum of the RDAI change and the standardized respiratory rate change between assessments with a decrease in RACS signifying improvement. (NCT01247064)
Timeframe: Baseline and 1 hour

Interventionunits on a scale (Mean)
Nebulized 3% Saline-1.5
Nebulized 0.9% Normal Saline-4

Respiratory Rate Change

(NCT01247064)
Timeframe: Baseline and 1 hour

Interventionbreaths per minute (Mean)
Nebulized 3% Saline-1.8
Nebulized 0.9% Normal Saline-9.8

Trials

1 trial available for terbutaline and Bronchiolitis, Viral

ArticleYear
Nebulized 3% hypertonic saline solution treatment in ambulatory children with viral bronchiolitis decreases symptoms.
    Chest, 2002, Volume: 122, Issue:6

    Topics: Adrenergic beta-Agonists; Aerosols; Bronchiolitis, Viral; Double-Blind Method; Female; Humans; Infan

2002
Nebulized 3% hypertonic saline solution treatment in ambulatory children with viral bronchiolitis decreases symptoms.
    Chest, 2002, Volume: 122, Issue:6

    Topics: Adrenergic beta-Agonists; Aerosols; Bronchiolitis, Viral; Double-Blind Method; Female; Humans; Infan

2002
Nebulized 3% hypertonic saline solution treatment in ambulatory children with viral bronchiolitis decreases symptoms.
    Chest, 2002, Volume: 122, Issue:6

    Topics: Adrenergic beta-Agonists; Aerosols; Bronchiolitis, Viral; Double-Blind Method; Female; Humans; Infan

2002
Nebulized 3% hypertonic saline solution treatment in ambulatory children with viral bronchiolitis decreases symptoms.
    Chest, 2002, Volume: 122, Issue:6

    Topics: Adrenergic beta-Agonists; Aerosols; Bronchiolitis, Viral; Double-Blind Method; Female; Humans; Infan

2002

Other Studies

1 other study available for terbutaline and Bronchiolitis, Viral

ArticleYear
[Bronchodilators in babies with wheezy bronchitis (author's transl)].
    Monatsschrift fur Kinderheilkunde, 1978, Volume: 126, Issue:11

    Topics: Asthma; Bronchiolitis, Viral; Bronchitis; Complement Fixation Tests; Female; Humans; Immunoglobulin

1978