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terbutaline and Bronchial Hyperreactivity

terbutaline has been researched along with Bronchial Hyperreactivity in 20 studies

Terbutaline: A selective beta-2 adrenergic agonist used as a bronchodilator and tocolytic.
terbutaline : A member of the class of phenylethanolamines that is catechol substituted at position 5 by a 2-(tert-butylamino)-1-hydroxyethyl group.

Bronchial Hyperreactivity: Tendency of the smooth muscle of the tracheobronchial tree to contract more intensely in response to a given stimulus than it does in the response seen in normal individuals. This condition is present in virtually all symptomatic patients with asthma. The most prominent manifestation of this smooth muscle contraction is a decrease in airway caliber that can be readily measured in the pulmonary function laboratory.

Research Excerpts

ExcerptRelevanceReference
" We undertook a randomized, crossover study to investigate the effects of 6 wk of treatment with regular terbutaline (1 mg four times a day), regular budesonide (400 microg twice a day), combined treatment, and placebo in subjects with mild to moderate asthma."9.09Effects of terbutaline and budesonide on sputum cells and bronchial hyperresponsiveness in asthma. ( Aldridge, RE; Cowan, JO; Frampton, CM; Hancox, RJ; Robin Taylor, D; Town, GI; Winn, MC, 2000)
"Atopy and bronchial responsiveness to histamine, exercise and bronchodilators were investigated in 18 adult patients with cystic fibrosis (CF)."7.68Bronchial vagal tone and responsiveness to histamine, exercise and bronchodilators in adult patients with cystic fibrosis. ( Festen, J; Lammers, JW; van Haren, EH; van Herwaarden, CL, 1992)
"Sixty one subjects with mild to moderate asthma were randomised to a double blind crossover comparison of inhaled budesonide (200-400 microg twice daily), terbutaline (500-1000 microg four times daily), combined treatment, and placebo."5.09Randomised trial of an inhaled beta2 agonist, inhaled corticosteroid and their combination in the treatment of asthma. ( Cowan, JO; Flannery, EM; Hancox, RJ; Herbison, GP; McLachlan, CR; Taylor, DR; Wong, CS, 1999)
" We undertook a randomized, crossover study to investigate the effects of 6 wk of treatment with regular terbutaline (1 mg four times a day), regular budesonide (400 microg twice a day), combined treatment, and placebo in subjects with mild to moderate asthma."5.09Effects of terbutaline and budesonide on sputum cells and bronchial hyperresponsiveness in asthma. ( Aldridge, RE; Cowan, JO; Frampton, CM; Hancox, RJ; Robin Taylor, D; Town, GI; Winn, MC, 2000)
"In a previous study, we found that two years of treatment with an inhaled corticosteroid, budesonide, was more effective than treatment with an inhaled beta 2-agonist, terbutaline, in patients with newly diagnosed, generally mild asthma."5.07Effects of reducing or discontinuing inhaled budesonide in patients with mild asthma. ( Haahtela, T; Järvinen, M; Kava, T; Kiviranta, K; Koskinen, S; Lehtonen, K; Nikander, K; Persson, T; Selroos, O; Sovijärvi, A, 1994)
"A 40-yr-old woman with severe chronic asthma complained that her regular nebulized albuterol was exacerbating her symptoms."3.68Paradoxical bronchoconstriction with nebulized albuterol but not with terbutaline. ( Finnerty, JP; Howarth, PH, 1993)
"Atopy and bronchial responsiveness to histamine, exercise and bronchodilators were investigated in 18 adult patients with cystic fibrosis (CF)."3.68Bronchial vagal tone and responsiveness to histamine, exercise and bronchodilators in adult patients with cystic fibrosis. ( Festen, J; Lammers, JW; van Haren, EH; van Herwaarden, CL, 1992)
"The effect of 5-amino-4-imidazolecarboxamide riboside (AICA riboside), a modulator of purine metabolism, was studied on antigen-induced bronchospasm in ovalbumin (OA)-sensitized guinea pigs."3.68Antagonism of airway reactivity induced by ovalbumin antigen in guinea pigs by 5-amino-4-imidazolecarboxamide riboside. ( Bergren, DR; Bergren, VA; Gruber, HE; Marquardt, DL; Townley, RG, 1991)
"Chronic obstructive pulmonary disease (COPD) is a syndrome of chronic progressive airflow limitation as a result of chronic inflammation of the airways and lung parenchyma."2.73Atomization inhalation of terbutaline and budesonide efficiently improved immunity and lung function of AECOPD patients. ( Li, X; Wei, L; Xiong, G; Xu, L, 2008)
" Bronchoconstrictor and bronchodilator responsiveness were assessed with cumulative dose-response curves, using histamine and terbutaline, respectively."1.30Lack of correlation between bronchoconstrictor response and bronchodilator response in a population-based study. ( de Gooijer, A; Douma, WR; Koëter, GH; Postma, DS; Rijcken, B; Schouten, JP; Weiss, ST, 1997)

Research

Studies (20)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's12 (60.00)18.2507
2000's6 (30.00)29.6817
2010's0 (0.00)24.3611
2020's2 (10.00)2.80

Authors

AuthorsStudies
Lai, K2
Yi, F2
Han, L2
Liu, B2
Zhang, X2
Xue, Y2
Luo, W2
Chen, Q2
Xiong, G1
Xu, L1
Wei, L1
Li, X1
Horiguchi, T2
Kondo, R2
Miyazaki, J2
Torigoe, H2
Tachikawa, S1
Fukumokto, K1
Mazzoni, L1
Naef, R1
Chapman, ID1
Morley, J1
Haahtela, T1
Järvinen, M1
Kava, T1
Kiviranta, K1
Koskinen, S1
Lehtonen, K1
Nikander, K1
Persson, T1
Selroos, O1
Sovijärvi, A1
Kerstjens, HA3
Overbeek, SE2
Schouten, JP2
Brand, PL2
Postma, DS4
Finnerty, JP1
Howarth, PH1
Källström, BL1
Sjöberg, J1
Waldeck, B1
Douma, WR2
de Gooijer, A2
Rijcken, B1
Koëter, GH2
Weiss, ST1
Portel, L1
Tunon de Lara, JM1
Vernejoux, JM1
Weiss, I1
Taytard, A1
Hancox, RJ2
Cowan, JO2
Flannery, EM1
Herbison, GP1
McLachlan, CR1
Wong, CS1
Taylor, DR1
Aldridge, RE1
Robin Taylor, D1
Winn, MC1
Frampton, CM1
Town, GI1
Nielsen, KG1
Bisgaard, H1
van Haren, EH1
Lammers, JW1
Festen, J1
van Herwaarden, CL2
Sterk, PJ1
Quanjer, PH1
Sluiter, HJ1
Dijkman, JH1
Hilvering, C1
Jansen, HM1
Wilts, M1
Hop, WC1
van der Heyden, GH1
Kerrebijn, KF1
de Jongste, JC1
Bergren, DR1
Townley, RG1
Marquardt, DL1
Gruber, HE1
Bergren, VA1

Trials

12 trials available for terbutaline and Bronchial Hyperreactivity

ArticleYear
Response to bronchodilator and clinical, pathophysiological features in patients with nonasthmatic eosinophilic bronchitis.
    The clinical respiratory journal, 2020, Volume: 14, Issue:3

    Topics: Administration, Oral; Adult; Airway Remodeling; Asthma; Bronchial Hyperreactivity; Bronchitis; Bronc

2020
Determinants of response to bronchodilator in patients with cough variant asthma- A randomized, single-blinded, placebo-controlled study.
    Pulmonary pharmacology & therapeutics, 2020, Volume: 61

    Topics: Adrenergic beta-2 Receptor Agonists; Adult; Aged; Asthma; Bronchial Hyperreactivity; Bronchial Provo

2020
Atomization inhalation of terbutaline and budesonide efficiently improved immunity and lung function of AECOPD patients.
    Cellular & molecular immunology, 2008, Volume: 5, Issue:4

    Topics: Administration, Inhalation; Aged; Bronchial Hyperreactivity; Bronchodilator Agents; Budesonide; C-Re

2008
[Clinical evaluation of tulobuterol patch in patients with mild or moderate persistent bronchial asthma-effects of long-term treatment on airway inflammation and hypersensitivity].
    Nihon Kokyuki Gakkai zasshi = the journal of the Japanese Respiratory Society, 2004, Volume: 42, Issue:2

    Topics: Administration, Cutaneous; Administration, Inhalation; Adrenergic beta-Agonists; Aged; Androstadiene

2004
Clinical evaluation of a transdermal therapeutic system of the beta2-agonist tulobuterol in patients with mild or moderate persistent bronchial asthma.
    Arzneimittel-Forschung, 2004, Volume: 54, Issue:5

    Topics: Administration, Cutaneous; Adult; Anti-Asthmatic Agents; Asthma; Blood Proteins; Bronchial Hyperreac

2004
Effects of reducing or discontinuing inhaled budesonide in patients with mild asthma.
    The New England journal of medicine, 1994, Sep-15, Volume: 331, Issue:11

    Topics: Administration, Inhalation; Adult; Asthma; Bronchial Hyperreactivity; Bronchodilator Agents; Budeson

1994
Airways hyperresponsiveness, bronchodilator response, allergy and smoking predict improvement in FEV1 during long-term inhaled corticosteroid treatment. Dutch CNSLD Study Group.
    The European respiratory journal, 1993, Volume: 6, Issue:6

    Topics: Administration, Inhalation; Adult; Asthma; Beclomethasone; Bronchi; Bronchial Hyperreactivity; Doubl

1993
Randomised trial of an inhaled beta2 agonist, inhaled corticosteroid and their combination in the treatment of asthma.
    Thorax, 1999, Volume: 54, Issue:6

    Topics: Administration, Inhalation; Adolescent; Adrenergic beta-Agonists; Adult; Anti-Inflammatory Agents; A

1999
Effects of terbutaline and budesonide on sputum cells and bronchial hyperresponsiveness in asthma.
    American journal of respiratory and critical care medicine, 2000, Volume: 161, Issue:5

    Topics: Administration, Topical; Adolescent; Adrenergic beta-Agonists; Adult; Anti-Inflammatory Agents; Asth

2000
Lung function response to cold air challenge in asthmatic and healthy children of 2-5 years of age.
    American journal of respiratory and critical care medicine, 2000, Volume: 161, Issue:6

    Topics: Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Bronchodilator Agents; Child, Presch

2000
Initial improvements in lung function and bronchial hyperresponsiveness are maintained during 5 years of treatment with inhaled beclomethasone dipropionate and terbutaline.
    Chest, 2002, Volume: 121, Issue:1

    Topics: Administration, Inhalation; Adult; Anti-Asthmatic Agents; Asthma; Beclomethasone; Bronchial Hyperrea

2002
Long-term multicentre trial in chronic nonspecific lung disease: methodology and baseline assessment in adult patients. Dutch CNSLD Study Group.
    The European respiratory journal, 1992, Volume: 5, Issue:1

    Topics: Adult; Asthma; Beclomethasone; Bronchial Hyperreactivity; Double-Blind Method; Follow-Up Studies; Fo

1992

Other Studies

8 other studies available for terbutaline and Bronchial Hyperreactivity

ArticleYear
Hyperresponsiveness of the airways following exposure of guinea-pigs to racemic mixtures and distomers of beta 2-selective sympathomimetics.
    Pulmonary pharmacology, 1994, Volume: 7, Issue:6

    Topics: Administration, Topical; Adrenergic beta-2 Receptor Agonists; Adrenergic beta-Agonists; Airway Resis

1994
Paradoxical bronchoconstriction with nebulized albuterol but not with terbutaline.
    The American review of respiratory disease, 1993, Volume: 148, Issue:2

    Topics: Adult; Aerosols; Albuterol; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Bronchoc

1993
Steric aspects of formoterol and terbutaline: is there an adverse effect of the distomer on airway smooth muscle function?
    Chirality, 1996, Volume: 8, Issue:8

    Topics: Adrenergic beta-Agonists; Animals; Bronchi; Bronchial Hyperreactivity; Carbachol; Choline; Electric

1996
Lack of correlation between bronchoconstrictor response and bronchodilator response in a population-based study.
    The European respiratory journal, 1997, Volume: 10, Issue:12

    Topics: Administration, Inhalation; Adolescent; Adult; Bronchi; Bronchial Hyperreactivity; Bronchial Provoca

1997
[Osmolarity of solutions used in nebulization].
    Revue des maladies respiratoires, 1998, Volume: 15, Issue:2

    Topics: Acetylcysteine; Administration, Inhalation; Aerosols; Albuterol; Anti-Asthmatic Agents; Bicarbonates

1998
Bronchial vagal tone and responsiveness to histamine, exercise and bronchodilators in adult patients with cystic fibrosis.
    The European respiratory journal, 1992, Volume: 5, Issue:9

    Topics: Adolescent; Adult; Bronchi; Bronchial Hyperreactivity; Bronchial Provocation Tests; Cystic Fibrosis;

1992
Measurement of bronchial responsiveness in young children: comparison of transcutaneous oxygen tension and functional residual capacity during induced bronchoconstriction and -dilatation.
    Pediatric pulmonology, 1992, Volume: 12, Issue:3

    Topics: Asthma; Blood Gas Monitoring, Transcutaneous; Bronchial Hyperreactivity; Bronchial Provocation Tests

1992
Antagonism of airway reactivity induced by ovalbumin antigen in guinea pigs by 5-amino-4-imidazolecarboxamide riboside.
    The Journal of allergy and clinical immunology, 1991, Volume: 88, Issue:4

    Topics: Aminoimidazole Carboxamide; Analysis of Variance; Animals; Bronchial Hyperreactivity; Bronchial Spas

1991