terbutaline has been researched along with Asthma in 824 studies
Terbutaline: A selective beta-2 adrenergic agonist used as a bronchodilator and tocolytic.
terbutaline : A member of the class of phenylethanolamines that is catechol substituted at position 5 by a 2-(tert-butylamino)-1-hydroxyethyl group.
Asthma: A form of bronchial disorder with three distinct components: airway hyper-responsiveness (RESPIRATORY HYPERSENSITIVITY), airway INFLAMMATION, and intermittent AIRWAY OBSTRUCTION. It is characterized by spasmodic contraction of airway smooth muscle, WHEEZING, and dyspnea (DYSPNEA, PAROXYSMAL).
| Excerpt | Relevance | Reference |
|---|---|---|
| "In adults with mild to moderate asthma, budesonide-formoterol used as needed for symptom relief was more effective at preventing severe exacerbations than maintenance low-dose budesonide plus as-needed terbutaline." | 9.30 | Budesonide-formoterol reliever therapy versus maintenance budesonide plus terbutaline reliever therapy in adults with mild to moderate asthma (PRACTICAL): a 52-week, open-label, multicentre, superiority, randomised controlled trial. ( Baggott, C; Beasley, R; Corin, A; Fingleton, J; Hall, D; Hancox, RJ; Hardy, J; Harwood, M; Holliday, M; Mane, S; Martindale, J; Reddel, HK; Sabbagh, D; Shirtcliffe, P; Sparks, J; Vohlidkova, A; Weatherall, M; Williams, M, 2019) |
| "This study compared the efficacy of intravenous magnesium sulphate, terbutaline and aminophylline for children with acute, severe asthma poorly responsive to standard initial treatment." | 9.19 | Randomised comparison of intravenous magnesium sulphate, terbutaline and aminophylline for children with acute severe asthma. ( Bansal, A; Chopra, K; Grover, S; Singhi, S, 2014) |
| "To compare tulobuterol patch and oral salbutamol sulfate in terms of efficacy and safety in children with mild or moderate acute attack of bronchial asthma." | 9.17 | [Efficacy and safety of tulobuterol patch versus oral salbutamol sulfate in children with mild or moderate acute attack of bronchial asthma: a comparative study]. ( Bao, YX; Lin, Q; Liu, QH, 2013) |
| "To evaluate the efficacy and tolerability of budesonide/formoterol as maintenance and reliever therapy versus budesonide/formoterol maintenance plus terbutaline in adults with persistent asthma not adequately controlled with inhaled corticosteroid (ICS) therapy alone." | 9.17 | Budesonide/formoterol maintenance and reliever therapy via Turbuhaler versus fixed-dose budesonide/formoterol plus terbutaline in patients with asthma: phase III study results. ( Aquino, T; Atienza, T; Boonsawat, W; Carlsson, LG; Ekelund, J; Fernández, M; Ivanov, S; Kawai, M; Kudo, T, 2013) |
| "Tulobuterol patch (Tulo) is often used for treatment of elder patient with asthma in Japan." | 9.16 | [Clinical effects of budesonide/formoterol combination drug in elder patients with asthma compared with budesonide plus tulobuterol patch combination treatment]. ( Haruta, Y; Kondoh, K; Mukaida, K; Onari, Y, 2012) |
| "Whether the additive effects of the tulobuterol patch (TP), the world's first transdermal beta2-agonist preparation, are useful in asthma patients receiving inhaled corticosteroid (ICS) is unclear." | 9.14 | Effects of the addition of Beta2-agonist tulobuterol patches to inhaled corticosteroid in patients with asthma. ( Haruta, Y; Hozawa, S; Terada, M; Yamakido, M, 2009) |
| "Formoterol therapy was at least as effective as terbutaline therapy in children and adolescents with mild and moderate asthma exacerbations." | 9.14 | A randomized, comparative study of formoterol and terbutaline dry powder inhalers in the treatment of mild to moderate asthma exacerbations in the pediatric acute care setting. ( Bussamra, MH; Cukier, A; Rodrigues, JC; Stelmach, R, 2009) |
| "Levels of 3-bromotyrosine and 3,5-dibromotyrosine were measured in sputum supernatants using stable isotope dilution gas chromatography-mass spectrometry in a randomized, placebo-controlled, crossover study of treatment with terbutaline, budesonide, and their combination in patients with persistent asthma." | 9.14 | Bromotyrosines in sputum proteins and treatment effects of terbutaline and budesonide in asthma. ( Aldridge, RE; Chan, T; Cowan, JO; Hancox, RJ; Kettle, AJ; Senthilmohan, R; Taylor, DR; Town, GI; van Dalen, CJ, 2009) |
| "In a quasi-randomized crossover design, children aged 5 months to 5 years with severe recurrent asthma episodes were treated either with inhaled budesonide 200 mcg or inhaled fluticasone 125 mcg delivered with a similar spacer." | 9.13 | Effectiveness of high repeated doses of inhaled budesonide or fluticasone in controlling acute asthma exacerbations in young children. ( Bilavsky, E; Nussinovitch, M; Volovitz, B, 2008) |
| "Nebulized terbutaline given at baseline and 6 h later was significantly more effective in improving PEFR and asthmatic symptoms (pulmonary index scores) for at least 12 h when the initial dose was administered in combination with intravenous betamethasone." | 9.12 | Comparison of the effects of nebulized terbutaline with or without intravenous betamethasone on exhaled nitric oxide in children with acute asthma attack. ( Hung, CH; Lee, MY; Tsai, YG; Yang, KD, 2006) |
| "Although frequently used to treat status asthmaticus in children, intravenous (IV) terbutaline has not been shown to decrease hospital length of stay (LOS)." | 9.12 | Protocol-based titration of intravenous terbutaline decreases length of stay in pediatric status asthmaticus. ( Carroll, CL; Schramm, CM, 2006) |
| "Patients with inadequately controlled asthma on inhaled corticosteroid (400 to 1,600 microg/day chlorofluorocarbon beclomethasone equivalent) were treated with concomitant salmeterol (n = 18) or sustained-release tulobuterol (patch) (n = 18), or the inhaled corticosteroid dose was doubled (add-on) (n = 13) to compare clinical efficacy." | 9.12 | Comparison of the clinical efficacy of salmeterol and sustained-release tulobuterol (patch) on inadequately controlled asthma patients on inhaled corticosteroids. ( Fujimoto, K; Komatsu, Y; Kubo, K; Urushihata, K; Yasuo, M, 2006) |
| "To evaluate the efficacy and safety of tulobuterol tape in mild and moderate persistent asthma patients." | 9.12 | [The efficacy and safety of tulobuterol tape in mild and moderate persistent asthma patients]. ( Cao, ZL; Chen, BY; Chen, X; He, J; He, QY; Lin, JT; Su, N; Xiao, Y; Yan, XX; Yang, M, 2007) |
| "Sixty-four patients with persistent asthma receiving 200 to 800 microg of fluticasone propionate daily were enrolled in this switchover study." | 9.12 | Addition of transdermal or inhaled long-acting Beta2-agonists in adult asthmatic patients treated with inhaled corticosteroids: switchover study from tulobuterol patch to salmeterol dry powder inhaler. ( Kita, H; Kobayashi, Y; Kudou, M; Yasuba, H, 2007) |
| "To compare the efficacy and tolerability of nebulized adrenaline and terbutaline in acute severe asthma." | 9.11 | Comparison of nebulized epinephrine and terbutaline in patients with acute severe asthma: a controlled trial. ( Adoun, M; Doré, P; Frat, JP; Godet, C; Robert, R; Rouffineau, J, 2004) |
| "5 microg) via Turbuhaler) are at least as safe as and associated with less systemic effects than multiple inhalations of the clinically equipotent dose of terbutaline (500 microg) in children with asthma." | 9.11 | Cumulative high doses of inhaled formoterol have less systemic effects in asthmatic children 6-11 years-old than cumulative high doses of inhaled terbutaline. ( Agertoft, L; Bengtsson, T; Johannes-Hellberg, I; Kaae, R; Nordvall, SL; Pedersen, S; Pedroletti, C; Rosenborg, J, 2004) |
| "To compare the clinical efficacy and side effects of terbutaline and salbutamol administered by metered dose inhaler and holding chamber in the mild to moderate acute exacerbations of asthma in children." | 9.11 | Comparison of terbutaline and salbutamol inhalation in children with mild or moderate acute exacerbation of asthma. ( Chandra, P; Kabra, SK; Lodha, R; Paliwal, L, 2004) |
| "5 mg terbutaline, both by Turbuhaler and used as needed, in addition to regular formoterol in moderate asthma." | 9.10 | Safety of formoterol by Turbuhaler as reliever medication compared with terbutaline in moderate asthma. ( Böszörményi, NG; Ind, PW; Pietinalho, A; Selroos, O; Shiner, RJ; Soliman, S; Villasante, C, 2002) |
| "To compare the efficacy of terbutaline sulphate delivered via Turbuhaler with a pressurised metered dose inhaler (pMDI) connected to Nebuhaler spacer in a population of asthmatic children presenting to emergency departments because of an acute episode of asthma." | 9.10 | Comparative efficacy of terbutaline sulphate delivered by Turbuhaler dry powder inhaler or pressurised metered dose inhaler with Nebuhaler spacer in children during an acute asthmatic episode. ( Cummins-McManus, B; Drblik, S; Gaudreault, P; Haddon, J; Lapierre, G; Lee, J; Spier, S; Thivierge, R; Turgeon, J; Verdy, I, 2003) |
| "To assess the bronchodilatory effect of loratadine in children with mild-to-moderate asthma and to determine whether loratadine interacts with terbutaline." | 9.10 | The bronchodilatory effects of loratadine, terbutaline, and both together versus placebo in childhood asthma. ( Baki, A; Orhan, F, 2003) |
| "To investigate dose proportionality, dosing frequency, and ethnic aspects of the pharmacokinetics of bambuterol in asthmatic children, and to discuss the relationship with previous observations in adults." | 9.09 | Pharmacokinetics of bambuterol during oral administration to asthmatic children. ( Ahlström, H; Alvero, J; Alvero, R; Espos, R; Fajutrao, L; Herrera, J; Kjellman, B; Kubista, J; Laxmyr, L; Leviste, C; Meyer, P; Nyberg, L; Oldaeus, G; Olsson, H; Rosenborg, J; Siricururat, A; Vichyanond, P; Weibull, E; Wettrell, G; Wong, E, 1999) |
| " We undertook a randomized, crossover study to investigate the effects of 6 wk of treatment with regular terbutaline (1 mg four times a day), regular budesonide (400 microg twice a day), combined treatment, and placebo in subjects with mild to moderate asthma." | 9.09 | Effects of terbutaline and budesonide on sputum cells and bronchial hyperresponsiveness in asthma. ( Aldridge, RE; Cowan, JO; Frampton, CM; Hancox, RJ; Robin Taylor, D; Town, GI; Winn, MC, 2000) |
| "5 microg provided better asthma control than terbutaline 0." | 9.09 | Comparison of formoterol and terbutaline for as-needed treatment of asthma: a randomised trial. ( Eivindson, A; Ekström, T; Löfdahl, CG; Postma, DS; Rasidakis, A; Schreurs, AG; Tattersfield, AE, 2001) |
| "We investigated the relationship between pulmonary deposition of terbutaline and bronchoprotection against methacholine and histamine with the Turbuhaler (AstraZeneca, Lund, Sweden) and a pressurized metered dose inhaler (pMDI) in 13 asthmatic patients." | 9.09 | Lung deposition and protective effect of terbutaline delivered from pressurized metered-dose inhalers and the Turbuhaler in asthmatic individuals. ( Borgström, L; Derom, E; Löfroos, AB; Pauwels, R; Van Schoor, J, 2001) |
| "The aim of this study was to evaluate if continuous treatment with budesonide or salmeterol influences the bronchodilator response to terbutaline in children with asthma; 23 children, aged 7 to 16 years (mean = 11 years), with mild asthma were treated with inhaled budesonide 100 micrograms b." | 9.08 | Influence of budesonide on the response to inhaled terbutaline in children with mild asthma. ( Agertoft, L; Fuglsang, G; Pedersen, S; Vikre-Jørgensen, J, 1995) |
| "The aim of the study was to compare the efficacy, tolerability and patient acceptability of bambuterol (Bambec) against controlled release (CR) salbutamol (Volmax) in the treatment of nocturnal asthma." | 9.08 | Comparison of the efficacy, tolerability and patient acceptability of once-daily bambuterol tablets against twice-daily controlled release salbutamol in nocturnal asthma. ACROBATICS Research Group. ( Ayres, JG; Gunn, SD; McConchie, SM, 1995) |
| "Bambuterol is a new long-acting oral bronchodilator for once daily use in patients with asthma." | 9.08 | One month treatment with the once daily oral beta 2-agonist bambuterol in asthmatic patients. ( Baas, A; Knight, A; Larsen, B; Olsson, H; Persson, G, 1995) |
| "Once-daily morning (7 AM) vs evening (10 PM) administration of the terbutaline prodrug bambuterol (20-mg tablet dose) was investigated in a double-blind, cross-over, randomized, and placebo-controlled study involving 29 diurnally active patients with asthma." | 9.08 | Bambuterol in the treatment of asthma. A placebo-controlled comparison of once-daily morning vs evening administration. ( D'Alonzo, GE; Feldman, S; Gnosspelius, Y; Karlsson, K; Smolensky, MH, 1995) |
| "This was a 4-week, open-label, parallel-group study designed to compare the efficacy and safety of the long-acting inhaled bronchodilator, salmeterol, with the established inhaled bronchodilator, terbutaline, in the treatment of patients with mild to moderate asthma." | 9.08 | A 4-week comparison of salmeterol and terbutaline in adult asthma. ( Hermansson, BA; Jenkins, RJ, 1995) |
| "0 mg of terbutaline, administered via Turbuhaler, in children with mild to moderate asthma, and to register peak inspiratory flow rates through Turbuhaler (PIFTBH)." | 9.08 | Dose response to inhaled terbutaline powder and peak inspiratory flow through Turbuhaler in children with mild to moderate asthma. ( Ribeiro, LB; Sandahl, G; Ståhl, E, 1996) |
| "Ninety children with acute asthma, equally divided into two study groups, were studied to compare the efficacy and safety of nebulized terbutaline with injected epinephrine in the treatment of acute exacerbation." | 9.08 | Terbutaline nebulization and epinephrine injection in treating acute asthmatic children. ( Chang, LF; Chu, CY; Hsieh, KH; Lin, YZ, 1996) |
| " The bronchodilator, cardiovascular, and tremorigenic responses following administration of salbutamol (SAL), terbutaline (TER) and fenoterol (FEN) by closed-port intermittent nebulization were compared for a period of 8 hr." | 9.08 | Efficacy and side effects of beta 2-agonists by inhaled route in acute asthma in children: comparison of salbutamol, terbutaline, and fenoterol. ( Naspitz, CK; Scalabrin, DM; Solé, D, 1996) |
| "The aim of this study was to investigate whether regular treatment with inhaled salmeterol modifies the dose-response curve to the inhaled short-acting beta2-agonist terbutaline or affects the concentration of nitric oxide (NO) in exhaled air of children with asthma." | 9.08 | Effect of salmeterol treatment on nitric oxide level in exhaled air and dose-response to terbutaline in children with mild asthma. ( Agertoft, L; Fuglsang, G; Pedersen, S; Vikre-Jørgensen, J, 1998) |
| "Eight patients with stable asthma weaned off beta2-agonist therapy were studied in a randomized, double-blinded, placebo-controlled study utilizing aerosolized terbutaline, 400 microg q6h." | 9.08 | Hemodynamic, cardiac, and electrolyte effects of low-dose aerosolized terbutaline sulfate in asthmatic patients. ( Braden, GL; Bria, WF; Germain, MJ; Hafer, JG; Mulhern, JG, 1998) |
| "Subcutaneous administration of epinephrine is as effective as terbutaline in treating acute attack of asthma in infants." | 9.08 | [Comparison of the effect of subcutaneous injection of adrenaline and terbutaline in asthma crisis in infants]. ( Khaldi, F; Salem, N, 1998) |
| "The aim of the multicenter, randomized, double-blind, double-dummy, parallel-group clinical trial with a 2-week treatment period was to compare the efficacy and safety of salmeterol (50 micrograms twice daily) with slow-release (SR) terbutaline (5 mg orally, twice daily) in nocturnal asthma." | 9.07 | Salmeterol compared with slow-release terbutaline in nocturnal asthma. A multicenter, randomized, double-blind, double-dummy, sequential clinical trial. French Multicenter Study Group. ( Bertin, L; Brambilla, C; Chastang, C; Georges, D, 1994) |
| " In order to investigate the possibility of replacing established treatment modalities with bambuterol once daily, we wanted to compare the bronchodilating and tremorogenic effects of bambuterol, 10 mg once daily, and terbutaline, 5 mg controlled-release (CR) tablets twice daily." | 9.07 | Therapeutic equivalence between bambuterol, 10 mg once daily, and terbutaline controlled release, 5 mg twice daily, in mild to moderate asthma. ( Fugleholm, AM; Ibsen, TB; Laxmyr, L; Svendsen, UG, 1993) |
| "We compared the bronchodilator response of terbutaline delivered either by a dry powder inhaler, the Turbuhaler, or by a metered-dose inhaler attached to a Nebuhaler inhaler in 10 children with stable asthma who were 3 to 6 years of age." | 9.07 | Comparison of inhaled terbutaline administered by either the Turbuhaler dry powder inhaler or a metered-dose inhaler with spacer in preschool children with asthma. ( Drblik, SP; Laberge, S; Spier, S; Turgeon, JP, 1994) |
| "Bambuterol was compared with placebo in 28 patients with nocturnal asthma in a randomized, double-blind cross-over study." | 9.07 | Bambuterol: effective in nocturnal asthma. ( Chookang, JY; Hassan, WU; Morrison, JF; Ning, AC; O'Reilly, JF; Pearson, SB; Petrie, GR; Shneerson, JM; Tang, OT; Turbitt, ML, 1993) |
| " In a double blind, randomised, crossover study the effect of preservatives in determining the airway responses to 5 mg of terbutaline was studied in a group of 21 atopic asthmatic patients." | 9.07 | Effect of preservative on the efficacy of terbutaline nebuliser solution in atopic asthma. ( Chan, CH; Lai, CK, 1993) |
| "A new long-acting bronchodilator prodrug, bambuterol hydrochloride, was tested in a randomized, crossover, and double-blind study in elderly asthmatic patients (aged 64 to 82 years)." | 9.07 | A placebo-controlled dose-finding study with bambuterol in elderly patients with asthma. ( Alexander, M; Aoki, FY; Grossman, RF; Knight, A; Sitar, DS; Soliman, S; Warren, CP, 1993) |
| "The effect of oral terbutaline (controlled-release [CR] tablets) was compared with that of inhaled ipratropium bromide (aerosol) in 21 patients with nocturnal asthma." | 9.07 | Terbutaline controlled-release tablets and ipratropium aerosol in nocturnal asthma. ( Elo, J; Mansury, L; Tammivaara, R, 1993) |
| "Effects of the inhaled corticosteroid budesonide and the oral beta-agonist bambuterol on the nocturnal worsening of asthma were studied in patients with allergic asthma with a circadian peak expiratory flow variation greater than or equal to 15% (group 1, n = 8) and less than 15% (group 2, n = 9)." | 9.07 | Effects of budesonide and bambuterol on circadian variation of airway responsiveness and nocturnal symptoms of asthma. ( Auffarth, B; Koëter, GH; Postma, DS; Tammeling, EP; Teengs, JP; Wempe, JB, 1992) |
| "We compared the changes in peak expiratory flow rate (PEFR), plasma potassium and plasma glucose during and after an infusion of the beta 2-agonist, terbutaline, in seven asthmatic subjects." | 9.07 | Pilot study to compare the bronchodilator and metabolic responses to terbutaline infusion in seven asthmatic subjects--are they correlated? ( Haffner, CA; Holder, R; Hughes, B; Kendall, MJ, 1992) |
| "In a double-blind cross-over study comparing the duration of action of 12 micrograms and 24 micrograms formoterol, 500 micrograms terbutaline and placebo, lung function tests were performed in 12 never-smokers with non-allergic bronchial asthma." | 9.07 | Effect of inhaled formoterol versus terbutaline on respiratory function in moderate bronchial asthma. ( Boman, G; Hedenström, H; Melander, B; Wåhlander, L; Wegener, T, 1992) |
| "Disposition and efficacy of bambuterol were studied in 10 younger (20 to 37 years) and 10 older (69 to 76 years) patients with asthma (nine men and 11 women) at steady state, after single daily doses of 20 mg (50 mumol) for 1 week." | 9.07 | Pharmacokinetics and pharmacodynamics of bambuterol, a long-acting bronchodilator pro-drug of terbutaline, in young and elderly patients with asthma. ( Aoki, FY; Sitar, DS; Warren, CP, 1992) |
| "We compared the effect of an inhaled corticosteroid, budesonide, and an inhaled beta 2-agonist, terbutaline, on clinical symptoms, lung function, and airway inflammation in 14 adult patients with newly diagnosed asthma." | 9.07 | A comparative study of the effects of an inhaled corticosteroid, budesonide, and a beta 2-agonist, terbutaline, on airway inflammation in newly diagnosed asthma: a randomized, double-blind, parallel-group controlled trial. ( Haahtela, T; Laitinen, A; Laitinen, LA, 1992) |
| "The effect of different methods of administration of inhaled terbutaline on mucociliary clearance and forced expiratory volume in one second (FEV1) was assessed in 10 patients with asthma and 10 healthy subjects." | 9.07 | Effect of terbutaline on mucociliary clearance in asthmatic and healthy subjects after inhalation from a pressurised inhaler and a dry powder inhaler. ( Groth, S; Hermansen, F; Lange, P; Mortensen, J, 1991) |
| "Our study investigated the differential effects of continuous or unequal day-night terbutaline dosing on circadian bronchial patency, heart rate, and arterial pressure in severe acute asthma." | 9.07 | Unequal day-night terbutaline i.v. dosing in acute severe asthma: effect on nocturnal bronchial patency, heart rate, and arterial pressure. ( Arnaud, A; Bruguerolle, B; Lagier, F; Leonardelli, M; Orlando, JP; Philip-Joet, F; Pierson, F; Reynaud, M; Vervloet, D, 1991) |
| "The effects of treatment with budesonide (200 micrograms twice daily) and terbutaline (500 micrograms four times daily) has been compared with the effects of placebo and terbutaline in 27 children with mild asthma, aged 7-14 years, in a double blind, randomised placebo controlled study over eight weeks." | 9.07 | Budesonide and terbutaline or terbutaline alone in children with mild asthma: effects on bronchial hyperresponsiveness and diurnal variation in peak flow. ( Gerritsen, J; Knol, K; Koëter, GH; Krouwels, FH; van Aalderen, WM; Waalkens, HJ, 1991) |
| "Antiinflammatory therapy with inhaled budesonide is an effective first-line treatment for patients with newly detected, mild asthma, and it is superior to the use of terbutaline in such patients." | 9.07 | Comparison of a beta 2-agonist, terbutaline, with an inhaled corticosteroid, budesonide, in newly detected asthma. ( Haahtela, T; Järvinen, M; Kava, T; Kiviranta, K; Koskinen, S; Lehtonen, K; Nikander, K; Persson, T; Reinikainen, K; Selroos, O, 1991) |
| "The airway response and cardiovascular and hypokalaemic effects of fenoterol, salbutamol, and terbutaline given in multiples of standard doses from metered-dose inhalers were studied in ten patients with mild asthma." | 9.06 | Bronchodilator, cardiovascular, and hypokalaemic effects of fenoterol, salbutamol, and terbutaline in asthma. ( Britton, JR; Pavord, ID; Tattersfield, AE; Williams, J; Wong, CS, 1990) |
| "Nine adult asthmatics with a history of nocturnal symptoms and with morning dips in peak expiratory flow (PEF) were treated for 10-14 days with 24-h controlled-release preparation of theophylline (Th), or a controlled-release preparation of terbutaline (Te), in a double-blind cross-over experiment." | 9.06 | Nocturnal oxygen saturation and body movement in asthmatics treated with controlled-release preparations of theophylline or terbutaline. ( Brander, PE; Hakulinen, A; Poppius, H; Salmi, T; Sovijärvi, AR, 1990) |
| "A study was carried out in 8 patients with chronic stable bronchial asthma to compare the bronchodilator response with terbutaline, administered by a recently developed powder inhalation system ('Turbuhaler') and equipotent doses of salbutamol administered by a widely used powder inhaler ('Rotahaler')." | 9.06 | Dose-effect relationship of terbutaline using a multi-dose powder inhalation system ('Turbuhaler') and salbutamol administered by powder inhalation ('Rotahaler') in asthmatics. ( Bogaard, JM; Slingerland, R; Verbraak, AF, 1989) |
| "The purpose of this study was to compare effect of treatment with an oral long-acting beta 2-agonist (sustained-release terbutaline, Bricanyl depot), an inhaled steroid (budesonide, Pulmicort), and the combined treatment in patients with nocturnal asthma." | 9.06 | Nocturnal asthma: effect of treatment with oral sustained-release terbutaline, inhaled budesonide, and the two in combination. ( Dahl, R; Hägglöf, B; Pedersen, B, 1989) |
| "To evaluate the long-term effects of slow-release formulations of theophylline and terbutaline on pulmonary function, clinical symptoms, and side effects, 24 children with stable and moderately severe perennial asthma participated in a prospective double-blind cross-over study." | 9.06 | Slow-release terbutaline and theophylline for the long-term therapy of children with asthma: a Latin square and factorial study of drug effects and interactions. ( Chow, OK; Fung, KP, 1989) |
| "We compared the use of terbutaline sulphate that was delivered by a nebulizer with its delivery by a Nebuhaler at two dose levels in 27 children (nine children per group) of between three and six years of age with acute asthma." | 9.06 | Comparative efficacy of terbutaline administered by Nebuhaler and by nebulizer in young children with acute asthma. ( Hopkins, J; Pendergast, J; Timms, B; Van Asperen, PP, 1989) |
| "A randomized clinical trial comparing subcutaneous epinephrine and terbutaline injections was conducted in asthmatic children at The Methodist Hospital, Brooklyn, New York." | 9.06 | Comparison between epinephrine and terbutaline injections in the acute management of asthma. ( Battista, CJ; Nangia, BS; Victoria, MS, 1989) |
| "The aim of this study was to evaluate the efficacy, safety and preference of pre-school children with regard to two different devices for treatment of bronchial asthma with terbutaline." | 9.06 | Treatment of asthma in pre-school children with inhalation of terbutaline in Turbuhaler compared with Nebuhaler. ( Ahlström, H; Svenonius, E; Svensson, M, 1989) |
| "In a group of ten patients with chronic asthmatic bronchitis, the effect of monotherapy with theophylline and terbutaline and the combination of both drugs, as sustained-release tablets, was compared to placebo, in a double-blind cross-over, triple dummy at random study." | 9.06 | Combination therapy of theophylline and terbutaline as sustained-release preparations in patients with asthmatic bronchitis. ( Fokkens, JK; Hamelink, MJ; Kreukniet, J; Maes, RA; van der Vet, AP; van Drost, RH, 1987) |
| "The beta 2-adrenoceptor mediated effects on ventilatory capacity, forced expiratory volume in one second (FEV1), forced ventilatory capacity (FVC), heart rate, and skeletal muscle tremor of a new controlled-release (CR) formulation of metoprolol, 100 mg and 200 mg, and of atenolol tablets, 100 mg, were studied in eight asthmatic patients." | 9.06 | Controlled-release metoprolol compared with atenolol in asthmatic patients: interaction with terbutaline. ( Dahlöf, C; Löfdahl, CG; Olofsson, B; Svedmyr, N; Westergren, G, 1988) |
| "52 severely ill asthmatic patients requiring acute admission to hospital entered a double-blind placebo-controlled trial to determine whether intravenous hydrocortisone given in addition to high-dose oral prednisolone and standard bronchodilator therapy accelerated recovery." | 9.06 | Need for intravenous hydrocortisone in addition to oral prednisolone in patients admitted to hospital with severe asthma without ventilatory failure. ( Ali, NJ; Harrison, BD; Hart, GJ; Robinson, AA; Stokes, TC; Vaughan, DA, 1986) |
| "Fifteen asthmatic patients participated in a dose-ranging study using tulobuterol syrup in single doses of 10 to 60 mcg/kg." | 9.06 | Tulobuterol in childhood asthma: single dose ranging and repeated oral dose comparative studies. ( Javier, MA; Noche, ML, 1986) |
| "The effects of single oral doses of atenolol 50 mg and xamoterol 200 mg (a recently developed partial beta 1-adrenoceptor agonist) on lung function, heart rate and blood pressure were investigated in 11 patients with asthma." | 9.06 | A comparative study on the ventilatory and haemodynamic effects of xamoterol and atenolol in asthmatic patients. ( Folgering, HT; Lammers, JW; Müller, ME; van Herwaarden, CL, 1986) |
| "The effect of long-term treatment with theophylline was studied in 20 chronic asthmatic patients receiving oral and inhaled beta 2-agonists." | 9.06 | Theophylline in maintenance treatment of chronic asthma: concentration-dependent additional effect to beta 2-agonist therapy. ( Billing, B; Dahlqvist, R; Hörnblad, Y; Leideman, T; Ripe, E; Skareke, L, 1987) |
| "Twenty-two asthmatics received bambuterol solution, a terbutaline pro-drug, once every evening." | 9.06 | Bambuterol: clinical effects of three doses of bambuterol once daily in asthmatic patients. ( Clemmensen, IH; Laursen, LC; Pedersen, BK; Ravn, S; Weeke, B, 1988) |
| "The effects of oral treatment with terbutaline sustained-release (SR) tablets (Bricanyl Depot) were studied in nine patients who had bronchial asthma and marked diurnal variation in ventilatory function." | 9.06 | Terbutaline sustained-release tablets in nocturnal asthma--a placebo-controlled comparison between a high and a low evening dose. ( Anehus, S; Dahl, R; Harving, H; Säwedal, L, 1988) |
| "We have investigated the use of subcutaneous terbutaline in 17 patients with brittle asthma and five patients with chronic severe asthma." | 9.06 | Long term treatment of severe asthma with subcutaneous terbutaline. ( Ayres, JG; Cochrane, GM; O'Driscoll, BR; Ruffles, SP, 1988) |
| "To evaluate whether the potency of a long-acting selective beta 2-agonist negates the need for cromolyn, 27 children, aged 6 to 12 years, with mild to moderate asthma requiring long-term medication, were assessed for the therapeutic effects of cromolyn and/or terbutaline by jet nebulizer." | 9.06 | Double-blind evaluation of nebulized cromolyn, terbutaline, and the combination for childhood asthma. ( Bierman, CW; Furukawa, CT; Menendez, R; Pierson, WE; Shapiro, GG; Sharpe, MJ, 1988) |
| "The effect of terbutaline, in a slow-release preparation, on spirometry and arterial blood-gases, was studied in fourteen patients with nocturnal asthma." | 9.06 | Nocturnal asthma: effects of slow-release terbutaline on spirometry and arterial blood-gases. ( Eklundh, G; Eriksson, L; Jonson, B; Persson, G, 1988) |
| "The objective of this open randomized cross-over study was to compare the clinical efficacy and safety of a recently introduced beta-2 mimetic, tulobuterol, with fenoterol in asthma patients." | 9.06 | Open cross-over comparison of tulobuterol and fenoterol in asthmatic adult patients. ( Azanza, JR; Dal-Re, R; Rivero, A; Sanchez, J, 1988) |
| "Twelve adult asthmatic patients participated in an open, randomized, cross-over comparison between cumulatively increasing doses of terbutaline sulphate administered via the multiple dose powder inhaler (Turbuhaler) or via a pressurized inhaler." | 9.06 | A new multiple dose powder inhaler, (Turbuhaler), compared with a pressurized inhaler in a study of terbutaline in asthmatics. ( Gruvstad, E; Persson, G; Ståhl, E, 1988) |
| "We compared the bronchodilating effects of intravenously administered enprofylline (2 mg/kg) with nebulized terbutaline (10 mg) in patients presenting to hospital with acute asthma in a multicenter double-blind parallel study." | 9.06 | Comparison of the effects of nebulized terbutaline with intravenous enprofylline in patients with acute asthma. ( Bryant, D; Burdon, J; Marlin, G; Mitchell, C; O'Hehir, R; Ruffin, R; Webb, S; Wilson, J; Woolcock, A, 1988) |
| "Subcutaneous adrenaline and terbutaline have been compared in a double blind study of 20 patients with acute severe asthma presenting to an accident and emergency department." | 9.06 | Subcutaneous adrenaline versus terbutaline in the treatment of acute severe asthma. ( Clarke, SW; Millar, AB; Pavia, D; Spiteri, MA, 1988) |
| "Twenty-three patients with acute severe asthma were treated in a randomized double-blind way by either intravenous terbutaline two times at an hour interval 6 micrograms/kg or inhaled terbutaline two times 0." | 9.06 | Intravenous versus nebulized terbutaline in patients with acute severe asthma; a double-blind randomized study. ( Elinck, W; Lamont, H; Pauwels, R; Van der Straeten, M; Van Renterghem, D, 1987) |
| "In fifteen patients with asthma tulobuterol, a new beta 2-adrenoceptor agonist, given by inhalation in 100 micrograms increments up to a cumulative dose of 600 micrograms produced dose related increases in both the FEV1 and FVC." | 9.06 | Bronchodilator activity of a new inhaled beta 2-adrenoceptor agonist, tulobuterol and its protective effect in exercise-induced asthma. ( Patel, KR, 1986) |
| "The efficacy and side effects of oral or inhaled terbutaline were examined in 13 mild-to-moderate asthmatic patients (ages 12 to 71 years) on maintenance theophylline (levels 10 to 25 micrograms/ml)." | 9.06 | Addition of terbutaline to optimal theophylline therapy. Double blind crossover study in asthmatic patients. ( Kray, KT; Nelson, HS; Vandewalker, ML; Weber, RW, 1986) |
| "The bronchodilator response to cumulative doses of terbutaline administered by metered dose inhaler with and without a conical spacer device and by Acorn nebuliser has been compared in groups of patients with chronic severe and moderately severe asthma." | 9.06 | Domiciliary comparison of terbutaline treatment by metered dose inhaler with and without conical spacer in severe and moderately severe chronic asthma. ( Gould, G; Kendrick, AH; Laszlo, G; O'Reilly, JF, 1986) |
| "The study was designed to compare terbutaline inhaled via a 750 ml spacer (Nebuhaler) with subcutaneous adrenaline injection as a first-line treatment for acute severe asthma." | 9.06 | Terbutaline pressurised aerosol inhaled via a Nebuhaler--an effective alternative to subcutaneous adrenaline for treatment of acute severe asthma. ( Charoenratanakul, S; Youngchaiyud, P, 1987) |
| "4 years who needed regular use of antiasthmatic drugs and showed after abandoning them with the appropriate intervals a FEV1 below 85% of their highest previous value, received in a randomized, double-blind crossover fashion two puffs of terbutaline 1 hour apart on two consecutive days." | 9.06 | [Bronchodilating effect of terbutaline inhaled with and without a tube spacer in asthmatic children]. ( Bilbao Aburto, A; Gutiérrez Mazorriaga, P; Ubetagoyena Arrieta, M; Vázquez Cordero, C, 1987) |
| "The equipotent bronchodilating doses of terbutaline and a new beta-agonist KWD 2131 with a relatively stronger anti-allergic (inhibition of mediator release) than bronchodilating effect given in nebulized form was estimated in eight patients with intrinsic asthma." | 9.05 | New beta-agonist, KWD 2131, compared with terbutaline in asthmatics. A cumulative dose-response study. ( Hegardt, B; Löwhagen, O; Svedmyr, N, 1980) |
| "The reproducibility of the histamine challenge in seven asymptomatic patients with extrinsic asthma, provoked four times each with 1-2 weeks interval, was investigated." | 9.05 | Histamine-induced bronchospasm. Its reproducibility and usage in clinical evaluation of the sub-threshold bronchodilating dose of a new beta-agonist, KWD 2131. ( Hegardt, B; Löwhagen, O; Svedmyr, N, 1980) |
| "The selective anti-allergic effect of a new beta-agonist, KWD 2131, in inhibiting allergen-provoked asthma was compared with that of placebo in a double-blind crossover study." | 9.05 | Evaluation of the protective effect of a new beta-agonist, KWD 2131, on allergen-induced bronchospasm. ( Hegardt, B; Löwhagen, O; Svedmyr, N, 1980) |
| "5 mg) combined with 280 mg anhydrous theophylline orally in the randomized, double-blind, cross-over study in eight asthmatics." | 9.05 | Effects of oral theophylline combined with oral and inhaled beta-2-adrenostimulants in asthmatics. ( Svedmyr, K, 1982) |
| "In 8 asthmatic patients a comparative study was performed of the ventilatory and haemodynamic effects of the beta 1-receptor stimulator prenalterol and the beta 2-receptor stimulator terbutaline infused in increasing doses after a placebo." | 9.05 | Ventilatory and haemodynamic effects of prenalterol and terbutaline in asthmatic patients. ( Greefhorst, AP; van Herwaarden, CL, 1983) |
| "To study the cardioselectivity of xamoterol, eight asthmatic patients took part in a randomised, double-blind, cross-over study, in which xamoterol or saline were infused, followed by four increasing doses of terbutaline i." | 9.05 | Effects of xamoterol (ICI 118,587) in asthmatic patients. ( Löfdahl, CG; Svedmyr, N, 1984) |
| "A study was performed to investigate changes in plasma cyclic adenosine monophosphate (cyclic AMP), peak expiratory flow and arterial blood gas tensions in response to running exercise and terbutaline sulphate aerosol in asthmatic patients regularly receiving sympathomimetic bronchodilator aerosols." | 9.05 | Plasma cyclic AMP levels in response to exercise and terbutaline sulphate aerosol in normal and asthmatic subjects. ( Anderson, SD; Bye, PT; Daviskas, E; Marty, JJ; Sampson, D, 1980) |
| "Eight asthmatic patients and two normal subjects performed two identical exercise tests 140 minutes apart (first test preceded by inhalation of saline and the second by terbutaline sulphate)." | 9.05 | Arterial plasma histamine levels at rest, and during and after exercise in patients with asthma: effects of terbutaline aerosol. ( Anderson, SD; Bye, PT; Ferris, L; Schoeffel, RE; Seale, JP; Taylor, KM, 1981) |
| "The acute bronchomotor effect of nabilone, a synthetic cannabinoid compound, was compared to that of terbutaline sulfate and placebo in six healthy and six asthmatic subjects." | 9.05 | Comparison of bronchial effects of nabilone and terbutaline in healthy and asthmatic subjects. ( Calvarese, B; Gong, H; Tashkin, DP, 1983) |
| "In 8 asthmatic subjects, serum concentrations of terbutaline were correlated with changes in volume of air expelled in the first second of forced expiration (FEV1), other parameters of lung function, c-AMP plasma concentrations and finger tremor values after administration of either 5 mg terbutaline sulphate orally, 0." | 9.05 | The effects of oral and subcutaneous administration of terbutaline in asthmatic patients. ( Bruynzeel, PL; Fokkens, JK; Kreukniet, J; Leferink, JG; Maes, RA; van den Berg, W, 1984) |
| "A study to compare the bronchodilator effect of salbutamol powder (Ventolin, 200 micrograms) administered via a Rotahaler (SR), with that of terbutaline sulphate (Bricanyl, 500 micrograms) administered via a Misthaler (TM) was carried out in 25 children with stable moderate to severe asthma." | 9.05 | Bronchodilator effects of salbutamol powder administered via Rotahaler and of terbutaline aerosol administered via Misthaler. A comparison study in children with asthma. ( Mellis, CM; Sharota, E; Simpson, SJ; Towns, SJ, 1983) |
| "In 11 asthmatic subjects the relative magnitude and the site of airway bronchoconstriction were compared after the oral administration of 40 mg of propranolol and 2." | 9.05 | Beta-blockers in bronchial asthma: effect of propranolol and pindolol on large and small airways. ( Argiropoulou, V; Louridas, G; Patakas, D; Tsara, V, 1983) |
| "A double-blind randomized study of 50 patients was conducted to evaluate the efficacy and safety of terbutaline sulfate aerosol and isoproterenol sulfate aerosol in the treatment of patients with moderate to severe asthma." | 9.05 | Terbutaline sulfate and isoproterenol sulfate (metered dose aerosols) in the treatment of asthma. ( Kemp, JP; Meltzer, EO; Orgel, HA; Welch, MJ, 1983) |
| "Seven asthmatic patients were studied in a single-blind randomized, crossover study after oral administration of 20 mg nifedipine or placebo." | 9.05 | Nifedipine--a calcium channel blocker--in asthmatic patients. Interaction with terbutaline. ( Löfdahl, CG; Svedmyr, K; Svedmyr, N, 1984) |
| "25 mg terbutaline sulfate on serum potassium (K+), sodium (Na+), glucose, and insulin in a group of asymptomatic asthmatics." | 9.05 | The effect of subcutaneously administered terbutaline on serum potassium in asymptomatic adult asthmatics. ( Burki, NK; Küng, M; White, JR, 1984) |
| "A bronchodilator aerosol, terbutaline sulphate, was administered to 18 asthmatic children, mean age 8." | 9.05 | Childhood asthma: improved efficacy of pressurized terbutaline aerosol by use of a 750-ml spacer. ( Hidinger, KG; Kjellman, NI, 1984) |
| "In a pilot study two patients with brittle asthma and two with morning dipping received terbutaline or a placebo administered subcutaneously either by continuous infusion or in injections every six hours." | 9.05 | Subcutaneous terbutaline and control of brittle asthma or appreciable morning dipping. ( Ayres, J; Cochrane, GM; Fish, DR; Skinner, C; Wheeler, DC; Wiggins, J, 1984) |
| "Patients with acute asthmatic attacks were prospectively randomized to receive either aerosolized terbutaline or subcutaneous epinephrine." | 9.05 | A comparative study of aerosolized terbutaline and subcutaneously administered epinephrine in the treatment of acute bronchial asthma. ( Baughman, RP; James, W; Ploysongsang, Y, 1984) |
| "The bronchodilator effect of 400 micrograms of salbutamol powder (2 capsules) administered by a rota-haler was compared with that of 500 micrograms of terbutaline (2 metered doses) administered as an aerosol via a tube-spacer in a group of ten stable asthmatic children (mean age 12 years)." | 9.05 | Comparison of salbutamol powder with terbutaline aerosol administered with a tube spacer in asthmatic children. ( Francis, PW; Kelly, CA; Zimmerman, PV, 1983) |
| "Eight asthmatic patients were investigated in a double-blind cross-over study after oral administration of 100 mg atenolol, 10 mg metoprolol and placebo." | 9.05 | Cardioselectivity of atenolol and metoprolol. A study in asthmatic patients. ( Löfdahl, CG; Svedmyr, N, 1981) |
| "A double-blind, placebo-controlled study of the haemodynamic and ventilatory effects of two beta 1-selective adrenoceptor blockers and their interaction with the beta 2-adrenoceptor agonist terbutaline was carried out in eight asthmatic patients." | 9.05 | Ventilatory and haemodynamic effects of terbutaline infusion during beta 1-selective blockade with metoprolol and acebutolol in asthmatic patients. ( Greefhorst, AP; van Herwaarden, CL, 1982) |
| "The effect of adding theophylline to treatment with a beta2-adrenoceptor stimulant was studied in 18 asthmatic children in a double-blind cross-over trial." | 9.05 | Combined treatment with sustained-release theophylline and beta2-adrenoceptor-stimulating agents in chronic childhood asthma. ( Foucard, T; Lindström, B; Lönnerholm, G, 1981) |
| "The peak response and the duration of bronchodilator effect were measured after four inhalations at 20 min intervals of 250 micrograms of aerosolized terbutaline in 13 patients with bronchial asthma." | 9.05 | Aerosolized terbutaline in asthmatics: development of subsensitivity with long-term administration. ( Nelson, HS; Smith, JA; Weber, RW, 1982) |
| "Ventilatory function and whole lung mucociliary clearance have been assessed in 10 patients with mild stable asthma following inhalation of 1 mg of the beta-adrenergic receptor agonist terbutaline sulphate (Bricanyl, Astra Pharmaceuticals) from a metered dose inhaler (MDI)." | 9.05 | Effects of terbutaline sulphate aerosol on bronchodilator response and lung mucociliary clearance in patients with mild stable asthma. ( Bateman, JR; Clarke, SW; Newman, SP; Pavia, D; Sheahan, NF, 1983) |
| "The bronchodilator response to aerosolized terbutaline and optimal doses of theophylline, given singly and in combination, was studied in ten patients with perennial asthma." | 9.05 | Theophylline and aerosolized terbutaline in the treatment of bronchial asthma. Double-blind comparison of optimal doses. ( Nelson, HS; Smith, JA; Weber, RW, 1980) |
| "In a double-blind crossover controlled study, intravenous (IV) or nebulized terbutaline was given to eight patients with moderately severe asthma on two separate days." | 9.05 | Comparison of intravenous and inhaled terbutaline in the treatment of asthma. ( Clark, TJ; Denison, DM; Payne, CR; Pierce, RJ; Williams, SJ, 1981) |
| "In patients with acute severe asthma, 5 mg of terbutaline by inhalation and 500 microgram intravenously in divided doses both produced equally effective but not maximal bronchodilatation." | 9.05 | Comparison of inhaled and intravenous terbutaline in acute severe asthma. ( Clark, TJ; Williams, SJ; Winner, SJ, 1981) |
| "Terbutaline sulphate (Bricanyl; Keatings) aerosol or placebo aerosol was administered in a randomized fashion to 26 asthmatic children with proven exercise-induced asthma." | 9.05 | The effect of terbutaline sulphate on exercise-induced asthma in children. ( Weinberg, EG, 1982) |
| "0 mg of terbutaline or placebo disclosed that terbutaline produced a highly significant protective effect against exercise-induced asthma." | 9.05 | Effect of oral terbutaline on exercise-induced asthma. ( O'Brien, SR; Sly, RM, 1982) |
| "The bioavailability of three different theophylline tablets (microcrystallinic theophylline, Theolair, Nuelin, 3M Riker), choline theophyllinate as a new film-coated tablet (Teovent, Ferrosan, Sweden) and theophyllaminopropanol (Oxyphylline, Draco, Sweden) was investigated in eight adult asthmatics and a randomized, double-blind, cross-over study." | 9.05 | Bioavailability of theophylline from three different tablets in asthmatic patients and their bronchodilating effects in combination with terbutaline inhalation. ( Mellstrand, T; Svedmyr, K; Svedmyr, N, 1982) |
| "The effect of the beta 1-selective adrenoceptor blocker, metoprolol, on ventilatory function was studied in eight asthmatic patients in relation to the plasma level of the agent following its administration in ordinary and slow-release tablets." | 9.05 | Ventilatory effects of ordinary and slow-release tablets of metoprolol in asthmatic patients. ( van den Bergh, JH; van Herwaarden, CL, 1981) |
| "The effects of fenoterol and terbutaline, new beta 2 selective bronchodilators each administered orally in five mgm doses, was assessed in 33 asthmatics treated for six weeks." | 9.05 | A comparison of oral terbutaline and fenoterol in asthma. ( Miller, WC; Rice, DL, 1980) |
| "Bronchodilation and side effects of 28 days treatment with either a full therapeutic dose of theophylline slow-release preparation 500 mg twice daily (400-600 mg), a slow-release terbutaline preparation 10 mg twice daily or combinations of the 2 drugs in full or half doses were evaluated in 31 asthmatic outpatients in a double-blind, randomized crossover design." | 9.05 | Long-term oral therapy of asthma with terbutaline and theophylline, alone and combined. ( Gnosspelius, Y; Gymose, E; Laursen, LC; Taudorf, E; Weeke, B, 1985) |
| "Procaterol, a new beta-2 adrenoceptor stimulant, was studied in a double-blind, placebo-controlled, cross-over trial in patients with bronchial asthma." | 9.05 | Procaterol and terbutaline in bronchial asthma. A double-blind, placebo-controlled, cross-over study. ( Dahl, R; Harving, H; Henriksen, J; Rønne, K; Schøler, P, 1985) |
| "The efficacy of terbutaline (1 mg) administered from pressurised aerosol through a nebuhaler was compared in a crossover trial with terbutaline (4 mg) as nebulised solution in 20 patients with acute severe asthma." | 9.05 | Pear shaped spacer nebuhaler compared with nebulised solution for terbutaline administration in acute severe asthma. ( Beasley, CR; O'Donnell, TV, 1985) |
| "Thirty children 8-13 years old, with perennial asthma and with a reversibility of greater than or equal to 20% in lung function (FEV1) were given a sustained-release preparation of terbutaline sulphate 5 mg twice a day and ordinary tablets 2." | 9.05 | Terbutaline depot tablets in childhood asthma. A double-blind controlled study. ( Foged, N; Høst, A; Ljungholm, K, 1985) |
| "Twenty-seven asthmatic outpatients were randomly treated with bambuterol 30 mg administered once daily before going to bed and sustained release terbutaline 10 mg twice daily in a 14 day, double blind cross over study." | 9.05 | Bambuterol: effects of a new anti-asthmatic drug. ( Faurschou, P; Gnosspelius, Y; Laursen, LC; Pedersen, BK; Weeke, B, 1985) |
| "The acute cardiopulmonary effects of oral albuterol, 4 mg, metaproterenol sulfate, 20 mg, and terbutaline sulfate, 5 mg, were compared over eight hours in 20 moderate to severe asthmatics." | 9.05 | Comparison of the acute cardiopulmonary effects of oral albuterol, metaproterenol, and terbutaline in asthmatics. ( Biedermann, AA; Chu, TJ; Wolfe, JD; Yamate, M, 1985) |
| "We studied the effect of oral terbutaline on serum theophylline levels in 12 children with asthma." | 9.05 | Reduction of serum theophylline levels by terbutaline in children with asthma. ( Danziger, Y; Garty, M; Ilfeld, D; Rosenfeld, JB; Varsano, I; Volwitz, B, 1985) |
| "We performed a double-blind crossover study to compare the effects of long-term treatment of inhaled budesonide and terbutaline on bronchial hyperreactivity in 17 patients with allergic asthma." | 9.05 | Changes in bronchial hyperreactivity induced by 4 weeks of treatment with antiasthmatic drugs in patients with allergic asthma: a comparison between budesonide and terbutaline. ( de Vries, K; Koëter, GH; Kraan, J; Sluiter, HJ; vd Mark, TW, 1985) |
| "Terbutaline, a new bronchodilator drug reported to have selective affinity for beta 2-adrenergic receptors, was compared with epinephrine in the treatment of 49 adult subjects with acute bronchial asthma." | 9.04 | A comparative study of subcutaneously administered terbutaline and epinephrine in the treatment of acute bronchial asthma. ( Henis, MM; Heurich, AE; Leffler, CT; Lyons, HA; Smith, PR, 1977) |
| "Comparison of the bronchodilator and cardiovascular effects of subcutaneous terbutaline and epinephrine in the treatment of acute asthmatic attacks in children disclosed that bronchodilation occurred with 5 min after subcutaneous injection of either drug (0." | 9.04 | Comparison of subcutaneous terbutaline with epinephrine in the treatment of asthma in children. ( Badiei, B; Faciane, J; Sly, RM, 1977) |
| "Twenty-one patients with asthma were studied in a double-blind manner for the effects of three aerosolized bronchodilators (isoproterenol, metaproterenol and terbutaline) on small, large and mixed airways, blood pressure, heart rate and various blood chemistries." | 9.04 | A comparative study of the aerosolized bronchodilators, isoproterenol, metaproterenol and terbutaline in asthma. ( Novey, HS; Roth, MJ; Wilson, AF, 1977) |
| "The effects of terbutaline, ephedrine, and placebo on the cardiovascular and pulmonary systems have been compared in 24 asthmatic children." | 9.04 | Terbutaline and ephedrine in asthmatic children. ( Avner, SE; Blumberg, BS; Blumberg, MZ; Ginchansky, EJ; Taylor, JC; Tinkelman, DG, 1977) |
| "The effect of administration of terbutaline on the pulmonary and cardiovascular systems was studied in ten children with status asthmaticus." | 9.04 | Terbutaline in the treatment of status asthmaticus. ( Davis, WJ; Mellins, RB; Pang, LM; Rodriguez-Martinez, F, 1977) |
| "We have compared bronchodilator responses to atropine and terbutaline in 39 chronic bronchitics and 16 stable asthmatics." | 9.04 | Comparative bronchodilator responses to atropine and terbutaline in asthma and chronic bronchitis. ( Chick, TW; Jenne, JW, 1977) |
| "In 17 patients with moderate to severe asthma, we compared acute bronchodilator effects of the following drugs or drug combinations using a double-blind crossover design: terbutaline, 5; aminophyline 400; terbutaline, 5, plus aminophyline, 400; terbutaline, 2." | 9.04 | Bronchodilator effects of terbutaline and aminophylline alone and in combination in asthmatic patients. ( Calvarese, B; Simmons, M; Tashkin, DP; Wolfe, JD, 1978) |
| "In a double-blind trial of six weeks' duration 30 chronic asthmatic outpatients were treated with 5 mg tablets of either fenoterol or terbutaline two to four times daily." | 9.04 | A comparative evaluation of fenoterol and terbutaline in the treatment of asthma. ( Chervinsky, P, 1978) |
| "Fenoterol and terbutaline, two long-acting beta 2-adrenoceptor agonists in aerosol form, were compared in an 8-wk randomized double-blind crossover study in 22 mild to moderately severe asthmatics." | 9.04 | Comparison of four weeks' treatment with fenoterol and terbutaline aerosols in adult asthmatics. A double-blind crossover study. ( Anderson, M; Dimmock, S; Green, M; Greenacre, JK; Mansfield, L; Trembath, PW; Wadsworth, J, 1979) |
| "In a double-blind, single-dose trial asthmatic children, ages two to six years, received 25, 50 or 100 ug/kg terbutaline and placebo on four consecutive days." | 9.04 | Terbutaline elixir in preschool children with chronic asthma. ( Archer, JW; Pagtakhan, RD; Pizey, DM; Simons, FE, 1979) |
| "A double-blind crossover trial was conducted in 10 asthmatic patients for comparison of fenoterol with salbutamol, in 12 other asthmatic patients for comparison of reproterol with salbutamol, and in 15 other asthmatic patients for comparison of terbutaline with salbutamol." | 9.04 | [The bronchospasmolytics salbutamol, fenoterol, terbutaline and reproterol. Their effects and side effects in asthmatics after inhalation with an electric nebulizer]. ( Budmiger, H; Kyd, K; Scherrer, M, 1978) |
| "The bronchodilating effect, circulatory effects, and subjective side effects of ibuterol hydrochloride, the di-isobutyric acid ester of terbutaline, at two dose levels (2 and 4 mg) were compared with those of 5 mg terbutaline sulphate in a double-blind cross-over study on 12 patients with asthma." | 9.04 | Comparison between ibuterol hydrochloride and terbutaline in asthma. ( Arner, B; Magnusson, PO, 1976) |
| "A double blind study of 5 asthmatic subjects in remission demonstrated that the severity of bronchoconstriction after exercise was decreased by a single oral dose of 5 mg of terbutaline." | 9.04 | The effect of terbutaline in exercise-induced asthma. ( Anderson, GD; Jones, NL; Morse, JL, 1976) |
| "Terbutaline administration given to pediatric patients experiencing a severe asthma exacerbation was not associated with decreased PICU or general hospital floor admission." | 8.12 | The Impact of Terbutaline as Adjuvant Therapy in the Treatment of Severe Asthma in the Pediatric Emergency Department. ( Adair, E; Dibaba, D; Fowke, JH; Snider, M, 2022) |
| "Terbutaline aerosol and budesonide suspension are commonly used in the treatment of bronchial asthma, and budesonide suspension has local high efficiency and anti-inflammatory effects." | 7.88 | Effect of terbutaline combined with budesonide in treatment of bronchial asthma and rehabilitation nursing. ( Lu, W; Ruihong, Z; Xiaoli, L, 2018) |
| "The use of continuous intravenous terbutaline treatment in severe asthma attacks has been hampered by the lack of well-powered clinical trials where effects of such treatment are described in detail." | 7.88 | Safety of Terbutaline for Treatment of Acute Severe Pediatric Asthma. ( Doymaz, S; Schneider, J, 2018) |
| "To investigate the influence of early initiation of IV terbutaline on the incidence of acute respiratory failure requiring mechanical ventilation in severe pediatric asthma." | 7.80 | Early administration of terbutaline in severe pediatric asthma may reduce incidence of acute respiratory failure. ( Doymaz, S; Sagy, M; Schneider, J, 2014) |
| "Long-term subcutaneous or intravenous infusion of terbutaline has been used to stabilize asthma in patients enduring frequent hospital admissions due to severe asthma despite maximum therapy." | 7.80 | Continuous terbutaline infusion in severe asthma in adults: a retrospective study of long-term efficacy and safety. ( Afridi, L; Ayres, JG; Mansur, AH; Sullivan, J; Wilson, D, 2014) |
| "Aggravation of asthmatic response (asthmatic attack, 2 cases) and adverse events (tremor, 1 case) due to a switch from a brand-name tulobuterol tape to a generic tape were recently reported." | 7.78 | [Questionnaire survey on the change of asthmatic response, adverse events and product usability due to drug switching between name-brand and generic tulobuterol tapes]. ( Hori, S; Izumi, T; Miki, A; Satoh, H; Sawada, Y, 2012) |
| "These findings suggest that polymorphisms of β(2)-AR 16 are related to nocturnal asthma and polymorphisms of β(2)-AR 27 are associated with the variable responses to the inhaled terbutaline in children with nocturnal and nonnocturnal asthma." | 7.77 | Polymorphisms of the β2-adrenergic receptor correlated to nocturnal asthma and the response of terbutaline nebulizer. ( Chen, SJ; Cheng, SN; Fan, HC; Huang, HL; Lee, MY; Wang, CC, 2011) |
| "The study was undertaken to investigate the influence of once-daily treatment with montelukast (Singulair; MSD; Glattbrugg, Switzerland) on levels of exhaled nitric oxide (eNO) and lung function in preschool children with asthma." | 7.73 | The effect of montelukast on exhaled nitric oxide and lung function in asthmatic children 2 to 5 years old. ( Hamacher, J; Minocchieri, S; Moeller, A; Straub, DA; Wildhaber, JH, 2005) |
| "We investigated the efficacy of nighttime transdermal tulobuterol (beta2-adrenoceptor agonist) chronotherapy for nocturnal asthma by assessing changes both in the frequency of symptoms and features of the circadian rhythm in peak expiratory flow (PEF), a measure of airway caliber." | 7.73 | Alteration of the circadian rhythm in peak expiratory flow of nocturnal asthma following nighttime transdermal beta2-adrenoceptor agonist tulobuterol chronotherapy. ( Burioka, N; Endo, M; Fukuoka, Y; Igawa, K; Miyata, M; Nakazaki, H; Shimizu, E; Suyama, H, 2005) |
| "(1) To determine the effect of intravenous terbutaline in children with acute severe asthma on parameters like heart rate, blood pressure, electrocardiogram and serum electrolytes; (2) to assess the safety profile and to evaluate the outcome of children treated with intravenous terbutaline for acute severe asthma." | 7.73 | Safety of intravenous terbutaline in acute severe asthma: a retrospective study. ( Kambalapalli, M; Nichani, S; Upadhyayula, S, 2005) |
| "A continuous subcutaneous infusion of terbutaline (CSIT) was used to treat 8 children with chronic severe asthma who continued to experience frequent symptoms, despite treatment with regular oral prednisolone." | 7.71 | Subcutaneous terbutaline in children with chronic severe asthma. ( Balfour-Lynn, IM; Biggart, EA; Bush, A; Payne, DN; Rosenthal, M, 2002) |
| "To examine the cardiac toxicity as measured by elevations in serum cardiac troponin T (cTnT) and to compare creatine kinase (CK) and creatine kinase MB (CK-MB) and findings on electrocardiography (ECG) as markers of cardiac toxicity with cTnT during the infusion of intravenous terbutaline for the treatment of severe asthma in children." | 7.70 | Cardiac toxicity of intravenous terbutaline for the treatment of severe asthma in children: a prospective assessment. ( Adams, MJ; Burns, JP; Chiang, VW; Lipshultz, SE; Rifai, N; Weiner, DL, 2000) |
| "We report the pharmacokinetics and pharmacodynamics of tulobuterol patch, HN-078, in the treatment of childhood asthma." | 7.69 | Pharmacokinetics and pharmacodynamics of the tulobuterol patch, HN-078, in childhood asthma. ( Akimoto, K; Ebisawa, M; Iikura, Y; Ishizu, H; Kabayama, H; Miura, K; Sakaguchi, N; Tsubaki, T; Uchiyama, H; Yagi, K, 1995) |
| "Thirty five young subjects with long standing bronchial asthma were studied for the effects of terbutaline misthaler (500 micrograms) during acute asthma." | 7.69 | Effect of inhaled terbutaline on platelet activity in bronchial asthma. ( Chari, VI; Khatri, DP; Nabar, ST; Nadkar, MY; Paidhungat, AJ; Prabhu, SR; Salgaonkar, DS, 1994) |
| "35 asthmatic patients, aged from 23 to 73 years, participated in an open study aimed to compare the efficacy and tolerance of terbutaline and budesonide administered in similar amounts with a metered-dose inhaler fitted with a spacer (Nebuhaler) or by a powder inhaler (Turbuhaler)." | 7.68 | [Efficacy and tolerance of terbutaline and budesonide administered via a pressurized aerosol inhaler or a Turbohaler in asthmatic patients]. ( Anderhub, HP; Langloh, P; Zellweger, JP, 1993) |
| "The purpose of this study was to investigate the effect of a constant infusion rate of terbutaline on circadian bronchial peak expiratory flow rate (PEFR), heart rate and arterial pressure in patients with asthma exacerbation." | 7.68 | Effects of a constant dose rate of terbutaline on circadian peak expiratory flow, heart rate and systolic arterial pressure in patients with asthma exacerbation. ( Arnaud, A; Bruguerolle, B; Lagier, F; Leonardelli, M; Orlando, JP; Philip-Joet, F; Pierson, F; Reynaud, M; Vervloet, D, 1992) |
| "An integrated pharmacokinetic-pharmacodynamic model was used to quantify the beta 2-blocking activity of metoprolol in seven asthmatic patients." | 7.68 | Quantification of metoprolol beta 2-adrenoceptor antagonism in asthmatic patients by pharmacokinetic-pharmacodynamic modelling. ( Braat, MC; Jonkers, RE; van Boxtel, CJ, 1992) |
| " Serum creatine kinase activity was compared in 13 patients with brittle asthma currently being treated with subcutaneous terbutaline and an age and sex matched control group of patients with moderate asthma having inhaled treatment only." | 7.68 | Creatine kinase activity in patients with brittle asthma treated with long term subcutaneous terbutaline. ( Ayres, JG; Finnegan, JA; Lawson, N; Sykes, AP, 1991) |
| "Since absorption of nebulized and subcutaneous terbutaline may be delayed or decreased during episodes of severe asthma, a preliminary trial of intravenous terbutaline was instituted in five adult patients with status asthmaticus." | 7.68 | Continuous intravenous terbutaline infusions for adult patients with status asthmaticus. ( Iber, C; O'Connell, MB, 1990) |
| "Forty-four Pediatric Intensive Care Unit (PICU) admissions for acute severe asthma in 27 children between 8/80 and 10/86 were reviewed to determine the safety of prolonged administration of frequently nebulized terbutaline." | 7.68 | Safety of frequent high dose nebulized terbutaline in children with acute severe asthma. ( Katz, R; Kelly, HW; McWilliams, BC; Murphy, S, 1990) |
| "Experiences in combined use of beta-adrenergic stimulants and cardioselective beta-receptor blocker Talinolol are reported in 3 patients in Status Asthmaticus." | 7.67 | [Combined use of talinolol and beta adrenergic stimulants in status asthmaticus. Report on 3 patients]. ( Knappe, J; Oltmanns, G; Schwela, H; Szeszat, S, 1984) |
| "The absorption and excretion profiles of orally administered terbutaline were investigated in 10 asthmatic patients who received a solution containing 5 mg of [3H]terbutaline sulphate." | 7.67 | Oral administration of terbutaline in asthmatic patients. ( Hörnblad, Y; Ripe, E; Tegnér, K, 1984) |
| "Seven asthmatic children (8-12 years) were given terbutaline sulphate intravenously (5." | 7.67 | Kinetics of terbutaline in asthmatic children. ( Hultquist, C; Kjellman, B; Lindberg, C; Nyberg, L; Wettrell, G, 1984) |
| "Nine children, 10-15 years old with chronic asthma, were treated for weekly periods with gradually increasing doses of oral terbutaline sulphate: 45, 79, 118 and 166 micrograms/kg (mean values) 3 times daily." | 7.67 | Oral terbutaline in chronic childhood asthma; effects related to plasma concentrations. ( Foucard, T; Lindström, B; Lönnerholm, G, 1984) |
| "Oral terbutaline in gradually increasing doses from 45 to 166 micrograms/kg three times daily was administered to asthmatic school children." | 7.67 | Dose, plasma concentration, and effect of oral terbutaline in long-term treatment of childhood asthma. ( Foucard, T; Lindström, B; Lönnerholm, G, 1984) |
| "Seven asthmatic children were given terbutaline intravenously." | 7.67 | Pharmacokinetics of intravenous terbutaline in asthmatic children. ( Hultquist, C; Kjellman, B; Lindberg, C; Nyberg, L; Wettrell, G, 1989) |
| "The protective effect of pre-exercise treatment with disodium cromoglycate (DC), terbutaline sulphate (TS) and thiazinamium methylsulphate (TM) on exercise-induced asthma (EIA) was investigated." | 7.67 | Comparison of disodium cromoglycate, terbutaline and thiazinamium in the prevention of exercise-induced asthma and its relation to non-specific bronchial responsiveness. ( Berg, WC; Gimeno, F; Steenhuis, EJ; van Veenen, R, 1985) |
| "The bronchodilator effect of three successive stable plasma terbutaline levels was studied in 10 children with asthma." | 7.67 | Dose-response relationships of intravenously administered terbutaline in children with asthma. ( Borgström, L; Fuglsang, G; Pedersen, S, 1989) |
| "A group of 10 patients with chronic asthmatic bronchitis was titrated with slow-release theophylline (Theolin Retard) to a steady state plasma theophylline level of 10 mg/l." | 7.67 | Pharmacodynamics (lung function tests, tremor measurements and cAMP determinations) of a single dose of 0.5 mg terbutaline subcutaneously during sustained-release theophylline medication in patients with asthmatic bronchitis. ( Drost, RH; Fokkens, JK; Hamelink, ML; Kreukniet, J; Maes, RA; van der Vet, AP, 1986) |
| "Twelve children with severe asthma were treated in an intensive care unit with continuously nebulized terbutaline at doses between 1." | 7.67 | Continuous terbutaline nebulization for the treatment of severe exacerbations of asthma in children. ( Aggarwal, J; Portnoy, J, 1988) |
| "We analyzed continuous nebulized terbutaline (CNT) therapy in 19 patients with 27 admissions for severe asthma and impending respiratory failure who failed to respond to our standard asthma protocol of methylprednisolone, aminophylline, and intermittently nebulized terbutaline." | 7.67 | Improvement in clinical asthma score and PaCO2 in children with severe asthma treated with continuously nebulized terbutaline. ( Custer, JR; Hurwitz, ME; Moler, FW, 1988) |
| "In order to localize the main site of action of the beta 2-adrenoceptor selective agonist terbutaline and the beta 1-adrenoceptor selective antagonist atenolol in the airways of asthmatic patients, we compared the effects of these drugs on maximal expiratory flow-volume (MEFV) curves when breathing air and when breathing a helium-oxygen (HeO2) mixture." | 7.67 | Effects of terbutaline and atenolol on large and small airways in asthmatic patients. ( Folgering, HT; Lammers, JW; Müller, ME; van Herwaarden, CL, 1988) |
| "The purpose of this study was to evaluate prospectively the occurrence of cardiac arrhythmias during the combined therapy with intravenous aminophylline and terbutaline in 29 consecutive patients with status asthmaticus." | 7.67 | Cardiac arrhythmias during the combined use of intravenous aminophylline and terbutaline in status asthmaticus. ( Chauvet, JP; Iung, B; Laaban, JP; Proteau, J; Psychoyos, I; Rochemaure, J, 1988) |
| "This is a summary of five pediatric cases of unresponsive status asthmaticus treated with frequent subcutaneous injections of terbutaline." | 7.67 | Frequent parenteral terbutaline in the treatment of status asthmaticus in children. ( Nelson, HS; Tipton, WR, 1987) |
| "In 12, symptom-free, asthmatic children, aged 5-10 years, responses (increases in FEV1) were measured to cumulative doses of inhaled terbutaline delivered by two methods: a) 5 breaths from a 750 ml spacer (Nebuhaler) attached to a metered dose aerosol (doses were 0." | 7.67 | A dose-response study of inhaled terbutaline administered via Nebuhaler or nebuliser to asthmatic children. ( Blackhall, MI; O'Donnell, SR, 1987) |
| "Three out of nine unstable asthmatics whose asthma is subjectively and objectively better controlled on continuous subcutaneous terbutaline infusions (6-12 mg/24 hours) developed tender indurated subcutaneous swellings at the infusion site." | 7.67 | An unusual local reaction to continuous subcutaneous infused terbutaline in unstable asthmatics. ( Cochrane, GM; Hartley, RB; Lewis, LD; O'Driscoll, BR, 1987) |
| "The concentrations of theophylline, terbutaline and salbutamol in post-mortem blood samples from 68 patients (17-85 years old) with asthma or chronic obstructive lung disease, 54 of whom had died of asthma, were analysed." | 7.67 | Post-mortem concentrations of salbutamol, terbutaline and theophylline in asthma patients. ( Boman, G; Lindsjö, M; Lindström, B; Strandberg, K; Wiholm, BE, 1987) |
| "The bronchodilatation achieved by the beta 2 agonist terbutaline sulphate given as nebulised aerosol from different devices has been measured in seven patients with mild asthma (mean FEV1 76% predicted) over two hours after inhalation." | 7.67 | Effect of aerosol particle size on bronchodilatation with nebulised terbutaline in asthmatic subjects. ( Clarke, SW; Clay, MM; Pavia, D, 1986) |
| "The study of terbutaline pharmacodynamics in patients with asthma is hampered by interfering stimuli when steady-state methods are employed." | 7.67 | Pharmacokinetic-pharmacodynamic modeling of terbutaline bronchodilation in asthma. ( Braat, MC; Oosterhuis, B; Roos, CM; Van Boxtel, CJ; Wemer, J, 1986) |
| "Terbutaline serum levels, c-AMP plasma levels and percentage improvement in FEV1, were strongly correlated after subcutaneous administration of terbutaline to normals (n = 6) and to asthmatics (n = 5)." | 7.66 | Correlation between terbutaline serum levels, c-AMP plasma levels and FEV1 in normals and asthmatics after subcutaneous administration. ( Bruynzeel, PL; Kreukniet, J; Leferink, JG; Van Den Berg, W, 1980) |
| "Repeated finger tremor measurements have been performed in six normal and eight asthmatic subjects after subcutaneous and oral administration of terbutaline." | 7.66 | Tremor measurement in asthma. II. Changes after terbutaline administration suggesting beta-adrenergic blockade. ( Bruynzeel, PL; Fokkens, J; Kreukniet, J; Leferink, JG; Maes, RA; van den Berg, W, 1982) |
| "Plasma terbutaline levels and peak expiratory flow rates were measured in 5 asthmatic children using doses of 0." | 7.66 | Plasma terbutaline levels in asthma. ( Dinwiddie, R; Frame, MH; Gewitz, M; Van der Laag, H, 1983) |
| "Eight patients with chronic severe asthma, poorly controlled by conventional doses of inhaled bronchodilator, were treated with high-dose inhaled terbutaline (4 mg four times daily), via either wet nebulisation of terbutaline respirator solution, or by tube-spacer aerosol, using cannisters delivering 1 mg terbutaline per metered dose." | 7.66 | High-dose inhaled terbutaline in the management of chronic severe asthma: comparison of wet nebulisation and tube-spacer delivery. ( Cochrane, GM; Nowell, RV; Prior, JG, 1982) |
| "The bronchodilating properties and side effects of theophylline and a beta 2-adrenoceptor stimulating drug (terbutaline) alone and in combination were studied in 10 adult asthmatic patients." | 7.66 | Separate and combined use of terbutaline and theophylline in asthmatics. Effects related to plasma levels. ( Billing, B; Dahlqvist, R; Garle, M; Hörnblad, Y; Ripe, E, 1982) |
| "A patient developed severe asthma following insulation of her house with urea-formaldehyde foam." | 7.66 | Asthma induced by dust from urea-formaldehyde foam insulating material. ( Filley, WV; Frigas, E; Reed, CE, 1981) |
| "Ten asthmatic children received regular daily therapy with terbutaline aerosol for 50 weeks." | 7.66 | Terbutaline aerosol in the long-term treatment of asthmatic children. ( Blackhall, MI; Macartney, B; O'Donnell, SR, 1981) |
| "We compared pulmonary function in 15 asthmatic subjects before and after ingestion of 5 mg terbutaline and placebo." | 7.66 | Site and duration of bronchodilation in asthmatic patients after oral administration of terbutaline. ( Fairshter, RD; Novey, HS; Wilson, AF, 1981) |
| "Sixteen patients with bronchial asthma participated in three studies of inhaled terbutaline." | 7.66 | Aerosolized terbutaline in asthmatics. Comparison of dosage strength, schedule, and method of administration. ( Nelson, HS; Petty, WE; Weber, RW, 1979) |
| "After a run-in period practolol was given in the dose of 100 mg twice daily to 29 patients with chronic bronchial asthma on the indication hypertension (12) and supraventricular arrhythmia (17)." | 7.65 | Effects of practolol in combination with terbutaline in the treatment of hypertension and arrhythmias in asthmatic patients. ( Eriksson, NE; Formgren, H, 1975) |
| "10 U kg(-1) inhaled human insulin was administered on each dosing day with or without prior administration of the bronchodilator terbutaline (in random order)." | 6.75 | The effect of terbutaline on the absorption of pulmonary administered insulin in subjects with asthma. ( Köhler, G; Korsatko, S; Olschewski, H; Petersen, AH; Pieber, TR; Råstam, J; Sparre, T; Wollmer, P; Wutte, A, 2010) |
| " The primary objective was to evaluate safety (pulse rate, blood pressure, adverse events, hematology, and clinical chemistry)." | 6.69 | One-year safety study with bambuterol once daily and terbutaline three times daily in 2-12-year-old children with asthma. The Bambuterol Multicentre Study Group. ( Kuusela, AL; Marenk, M; Olsson, H; Persson, B; Sandahl, G; Valovirta, E; Zarkovic, JP, 2000) |
| " The study showed improved bronchodilation when PEP was combined with inhalation of beta 2-agonist compared with beta 2-agonist alone." | 6.67 | Treatment of bronchial asthma with terbutaline inhaled by conespacer combined with positive expiratory pressure mask. ( Dahl, R; Frischknecht-Christensen, E; Nørregaard, O, 1991) |
| " The slow-release tablets were preferred by 15 of 18 children and their families when the effects, side effects and dosage were evaluated." | 6.66 | Terbutaline slow-release tablets in children with asthma. A comparison with t.i.d. beta 2-agonist therapy. ( Croner, S; Gustafsson, M; Kjellman, NI; Säwedal, L, 1986) |
| "The pharmacokinetic mechanism of the theophylline-terbutaline interaction has been studied." | 6.66 | Increased theophylline clearance in asthmatic patients due to terbutaline. ( Garty, M; Ilfeld, DN; Mazar, A; Paul-Keslin, L; Rosenfeld, JB; Spitzer, S, 1989) |
| "Enprofylline is a novel xanthine derivative with negligible adenosine antagonizing ability." | 6.66 | Additive bronchodilator effects of terbutaline and enprofylline in asthma. ( Lunell, E; Rasmussen, JB, 1987) |
| " After the terbutaline dose-response curve was determined, terbutaline was inhaled three times in increasing doses." | 6.65 | Pafenolol, a highly selective beta 1-adrenoceptor-antagonist, in asthmatic patients: interaction with terbutaline. ( Löfdahl, CG; Marlin, GE; Svedmyr, N, 1983) |
| "Twenty-five patients with chronic bronchial asthma completed the trial." | 6.65 | A comparison of sustained-release terbutaline with ordinary salbutamol in bronchial asthma. ( Beskow, R; Ericsson, CH; Grönneberg, R; Sjögren, I; Skedinger, M, 1984) |
| " This study indicates that the bronchodilating effect of terbutaline administered via the spacer is dose-dependent at the first inhalation, and that succeeding inhalations show no dose-response effects." | 6.65 | Cumulative dose response study comparing clinical effects of two doses of terbutaline sulphate administered via a 750 ml spacer to asthmatic patients. ( Franck, K; Laursen, LC; Munch, EP; Taudorf, E; Weeke, B, 1984) |
| "125 mg given intramuscularly, while this dosage elicited maximal bronchodilator effect." | 6.65 | Cardiovascular effects of intramuscular or inhaled terbutaline in asthmatics. ( Buch, J; Bundgaard, A, 1984) |
| "A sustained release preparation of terbutaline sulphate has been formulated (Bricanyl depot tablets) in order to extend the duration and accordingly change the dosage regimen to twice a day." | 6.65 | Terbutaline depot tablets in asthma. A clinical evaluation. ( Bundgaard, A; Fagerström, PO; Taudorf, E; Weeke, B; Weeke, E, 1981) |
| "Terbutaline is a safe bronchodilator drug when administered orally in 2." | 6.65 | Safety and effectiveness of terbutaline in children with chronic asthma. ( Gavani, UD; Hyde, JS; Khurana, S; Manaligod, LM, 1979) |
| "25 mg/puff) when administered as metered aerosol in a dosage of one puff followed by two puffs 30 min later produced the same maximum improvement of ventilatory function." | 6.64 | Hexoprenaline and terbutaline administered by inhalation. A comparison between two beta2-adrenoreceptor agonists with respect to effect on bronchial obstruction, heart rate, blood pressure and muscle tremor. ( Hörnblad, Y; Leideman, T; Ripe, E, 1978) |
| " Usually, oral dosage forms of beta 2-agonists have been used, but side effects such as palpitation and tremor have been reported because of excessive serum levels around Tmax." | 6.41 | [Development of transdermal formulation of tulobuterol for the treatment of bronchial asthma]. ( Kato, H; Nagata, O; Nakano, Y; Suzuki, T; Yamazaki, M, 2002) |
| "Bronchial asthma is a chronic disease which is currently treated using various inhalants." | 5.62 | Sustained release of tulobuterol from graphene oxide laden hydrogel to manage asthma. ( Chen, Y; Jin, S; Luo, L; Luo, S; Wu, B; Xu, C; Yang, T, 2021) |
| "Terbutaline is used for the management of bronchospasm associated with asthma, bronchitis, emphysema, and chronic obstructive pulmonary disease." | 5.41 | Clinical pharmacokinetics of terbutaline in humans: a systematic review. ( Ashraf, W; Imran, I; Majeed, A; Rasool, MF; Rehman, AU; Saeed, H; Sultan, K; Zamir, A, 2023) |
| "We analyzed daily peak expiratory flow and symptom scores recorded by participants in the SAKURA study (NCT00839800), an international multicentre randomized controlled trial comparing budesonide/formoterol as maintenance and reliever therapy versus budesonide/formoterol maintenance plus terbutaline as reliever, in adults with persistent asthma." | 5.41 | Detecting asthma exacerbations using daily home monitoring and machine learning. ( Gonem, S; Minku, LL; Zhang, O, 2021) |
| "In adolescents with mild asthma, as-needed BUD-FORM was superior to as-needed terbutaline for severe exacerbation reduction, with similar efficacy to BUD maintenance." | 5.41 | Efficacy and Safety of As-Needed Budesonide-Formoterol in Adolescents with Mild Asthma. ( Alagappan, VKT; Barnes, PJ; Bateman, ED; FitzGerald, JM; Ivanov, S; Lamarca, R; O'Byrne, PM; Puu, M; Reddel, HK; Zheng, J, 2021) |
| " Our findings suggested that the initial dosage of theophylline should be adjusted according to the gender of pediatric patients and particularly in the case of infants." | 5.35 | Effect of gender on theophylline clearance in the asthmatic acute phase in Japanese pediatric patients. ( Igarashi, T; Iwakawa, S, 2009) |
| "We suggest that this treatment of bronchial asthma may protect against endotoxin contained in inhaled house dust." | 5.35 | Tulobuterol patch maintains diaphragm muscle contractility for over twenty-four hours in a mouse model of sepsis. ( Miura, M; Murakami, Y; Nishio, T; Sasaki, K; Shindoh, C; Shishido, R, 2009) |
| "The PRACTICAL study was a 52-week, open-label, parallel group, randomised controlled trial of 890 adults with mild to moderate asthma, who were randomised to budesonide/formoterol Turbuhaler 200/6mcg one actuation as required or budesonide Turbuhaler 200mcg one actuation twice daily and terbutaline Turbuhaler 250mcg two actuations as required." | 5.34 | Combination budesonide/formoterol inhaler as sole reliever therapy in Māori and Pacific people with mild and moderate asthma. ( Baggott, C; Fingleton, J; Hancox, RJ; Hardy, J; Harwood, M; Holliday, M; Semprini, A; Tewhaiti-Smith, J; Weatherall, M, 2020) |
| "2." | 5.31 | Effects of sustained-release tulobuterol on asthma control and beta-adrenoceptor function. ( Ito, Y; Kondo, M; Kume, H; Suzuki, R; Takagi, K; Yamaki, K, 2002) |
| "In adults with mild to moderate asthma, budesonide-formoterol used as needed for symptom relief was more effective at preventing severe exacerbations than maintenance low-dose budesonide plus as-needed terbutaline." | 5.30 | Budesonide-formoterol reliever therapy versus maintenance budesonide plus terbutaline reliever therapy in adults with mild to moderate asthma (PRACTICAL): a 52-week, open-label, multicentre, superiority, randomised controlled trial. ( Baggott, C; Beasley, R; Corin, A; Fingleton, J; Hall, D; Hancox, RJ; Hardy, J; Harwood, M; Holliday, M; Mane, S; Martindale, J; Reddel, HK; Sabbagh, D; Shirtcliffe, P; Sparks, J; Vohlidkova, A; Weatherall, M; Williams, M, 2019) |
| "terbutaline because of bronchoconstriction (dosage not documented)." | 5.30 | [Acute theophylline intoxication as differential diagnosis of pneumothorax in an asthma patient]. ( Schaarschmidt, S; Standl, T, 1997) |
| "Seventeen asthmatic patients with acute airway obstruction had either IT or eFE on 2 consecutive days." | 5.29 | 'Functional relaxation' reduces acute airway obstruction in asthmatics as effectively as inhaled terbutaline. ( Hahn, EG; Loew, TH; Martus, P; Siegfried, W; Tritt, K, 1996) |
| "In patients with mild asthma, as-needed budesonide-formoterol provided superior asthma-symptom control to as-needed terbutaline, assessed according to electronically recorded weeks with well-controlled asthma, but was inferior to budesonide maintenance therapy." | 5.27 | Inhaled Combined Budesonide-Formoterol as Needed in Mild Asthma. ( Barnes, PJ; Bateman, ED; FitzGerald, JM; Ivanov, S; Jorup, C; Keen, C; Lamarca, R; O'Byrne, PM; Reddel, HK; Zhong, N, 2018) |
| "Pretreatment with lidocaine, the beta-receptor agonist, terbutaline, or the adenosine non-blocking xanthine, enprofylline, inhibited the capsaicine induced inflammatory response." | 5.27 | Anti-asthma drugs and capsaicine-induced microvascular effects in lower airways. ( Erjefält, I; Persson, CG, 1985) |
| " Some important parameters are the biological half-life at 3." | 5.26 | Pharmacokinetics of terbutaline, a beta 2-sympathomimetic, in healthy volunteers and asthmatic patients. ( Kreukniet, J; Leferink, JG; Maes, RA; van den Berg, W; Wagemaker-Engels, I, 1982) |
| " The receptors were tested by infusion of increasing doses of isoprenaline, so that dose-response curves for isoprenaline were recorded." | 5.26 | Lack of bronchial beta adrenoceptor resistance in asthmatics during long-term treatment with terbutaline. ( Larsson, S; Svedmyr, N; Thiringer, G, 1977) |
| " Tachycardia is a side effect which limits dosage in a few patients only." | 5.26 | Comparison of infused and inhaled terbutaline in patients with asthma. ( Svedmyr, N; Thiringer, G, 1976) |
| "This study compared the efficacy of intravenous magnesium sulphate, terbutaline and aminophylline for children with acute, severe asthma poorly responsive to standard initial treatment." | 5.19 | Randomised comparison of intravenous magnesium sulphate, terbutaline and aminophylline for children with acute severe asthma. ( Bansal, A; Chopra, K; Grover, S; Singhi, S, 2014) |
| "To compare tulobuterol patch and oral salbutamol sulfate in terms of efficacy and safety in children with mild or moderate acute attack of bronchial asthma." | 5.17 | [Efficacy and safety of tulobuterol patch versus oral salbutamol sulfate in children with mild or moderate acute attack of bronchial asthma: a comparative study]. ( Bao, YX; Lin, Q; Liu, QH, 2013) |
| "To evaluate the efficacy and tolerability of budesonide/formoterol as maintenance and reliever therapy versus budesonide/formoterol maintenance plus terbutaline in adults with persistent asthma not adequately controlled with inhaled corticosteroid (ICS) therapy alone." | 5.17 | Budesonide/formoterol maintenance and reliever therapy via Turbuhaler versus fixed-dose budesonide/formoterol plus terbutaline in patients with asthma: phase III study results. ( Aquino, T; Atienza, T; Boonsawat, W; Carlsson, LG; Ekelund, J; Fernández, M; Ivanov, S; Kawai, M; Kudo, T, 2013) |
| "Tulobuterol patch (Tulo) is often used for treatment of elder patient with asthma in Japan." | 5.16 | [Clinical effects of budesonide/formoterol combination drug in elder patients with asthma compared with budesonide plus tulobuterol patch combination treatment]. ( Haruta, Y; Kondoh, K; Mukaida, K; Onari, Y, 2012) |
| "Whether the additive effects of the tulobuterol patch (TP), the world's first transdermal beta2-agonist preparation, are useful in asthma patients receiving inhaled corticosteroid (ICS) is unclear." | 5.14 | Effects of the addition of Beta2-agonist tulobuterol patches to inhaled corticosteroid in patients with asthma. ( Haruta, Y; Hozawa, S; Terada, M; Yamakido, M, 2009) |
| "Formoterol therapy was at least as effective as terbutaline therapy in children and adolescents with mild and moderate asthma exacerbations." | 5.14 | A randomized, comparative study of formoterol and terbutaline dry powder inhalers in the treatment of mild to moderate asthma exacerbations in the pediatric acute care setting. ( Bussamra, MH; Cukier, A; Rodrigues, JC; Stelmach, R, 2009) |
| "Levels of 3-bromotyrosine and 3,5-dibromotyrosine were measured in sputum supernatants using stable isotope dilution gas chromatography-mass spectrometry in a randomized, placebo-controlled, crossover study of treatment with terbutaline, budesonide, and their combination in patients with persistent asthma." | 5.14 | Bromotyrosines in sputum proteins and treatment effects of terbutaline and budesonide in asthma. ( Aldridge, RE; Chan, T; Cowan, JO; Hancox, RJ; Kettle, AJ; Senthilmohan, R; Taylor, DR; Town, GI; van Dalen, CJ, 2009) |
| "In a 3-year study, adult patients who recently developed asthma (symptoms for less than 1 year) were treated for 2 years with the inhaled corticosteroid (ICS) budesonide (early therapy) or terbutaline." | 5.14 | Thirteen-year follow-up of early intervention with an inhaled corticosteroid in patients with asthma. ( Haahtela, T; Kava, T; Malmberg, LP; Nikander, K; Persson, T; Rytilä, P; Selroos, O; Tamminen, K, 2009) |
| "To compare the cost-effectiveness of budesonide/formoterol in a single inhaler used as Maintenance and Reliever Therapy (SMART) versus fixed higher-dose budesonide/formoterol plus as-needed terbutaline reliever (FHDBF) or fixed dose fluticasone/salmeterol plus as-needed terbutaline reliever (FDFS) in controlling asthma in adults and adolescents." | 5.13 | Budesonide/formoterol as maintenance and reliever treatment compared to fixed dose combination strategies - a Canadian economic evaluation. ( FitzGerald, JM; Miller, E, 2008) |
| "In a quasi-randomized crossover design, children aged 5 months to 5 years with severe recurrent asthma episodes were treated either with inhaled budesonide 200 mcg or inhaled fluticasone 125 mcg delivered with a similar spacer." | 5.13 | Effectiveness of high repeated doses of inhaled budesonide or fluticasone in controlling acute asthma exacerbations in young children. ( Bilavsky, E; Nussinovitch, M; Volovitz, B, 2008) |
| "Nebulized terbutaline given at baseline and 6 h later was significantly more effective in improving PEFR and asthmatic symptoms (pulmonary index scores) for at least 12 h when the initial dose was administered in combination with intravenous betamethasone." | 5.12 | Comparison of the effects of nebulized terbutaline with or without intravenous betamethasone on exhaled nitric oxide in children with acute asthma attack. ( Hung, CH; Lee, MY; Tsai, YG; Yang, KD, 2006) |
| "To compare a novel asthma management strategy--budesonide/formoterol in a single inhaler for both maintenance therapy and symptom relief--with a higher dose of budesonide plus as-needed terbutaline." | 5.12 | Budesonide/formoterol in a single inhaler for maintenance and relief in mild-to-moderate asthma: a randomized, double-blind trial. ( Atienza, T; Balanzat, AM; Jorup, C; Lier, PA; Pizzichini, E; Rabe, KF; Romero, S; Ställberg, B, 2006) |
| "Although frequently used to treat status asthmaticus in children, intravenous (IV) terbutaline has not been shown to decrease hospital length of stay (LOS)." | 5.12 | Protocol-based titration of intravenous terbutaline decreases length of stay in pediatric status asthmaticus. ( Carroll, CL; Schramm, CM, 2006) |
| "To assess the effectiveness of distinct salbutamol and terbutaline doses delivered via an MDI with spacer for the treatment of acute asthma in the pediatric emergency department." | 5.12 | [Bronchodilators via metered-dose inhaler with spacer in the pediatric emergency department: what is the dosage?]. ( Benito Fernández, J; González Díaz, C; Landa Garriz, M; Mintegi Raso, S; Trebolazabala Quirante, N, 2006) |
| "Patients with inadequately controlled asthma on inhaled corticosteroid (400 to 1,600 microg/day chlorofluorocarbon beclomethasone equivalent) were treated with concomitant salmeterol (n = 18) or sustained-release tulobuterol (patch) (n = 18), or the inhaled corticosteroid dose was doubled (add-on) (n = 13) to compare clinical efficacy." | 5.12 | Comparison of the clinical efficacy of salmeterol and sustained-release tulobuterol (patch) on inadequately controlled asthma patients on inhaled corticosteroids. ( Fujimoto, K; Komatsu, Y; Kubo, K; Urushihata, K; Yasuo, M, 2006) |
| "To evaluate the efficacy and safety of tulobuterol tape in mild and moderate persistent asthma patients." | 5.12 | [The efficacy and safety of tulobuterol tape in mild and moderate persistent asthma patients]. ( Cao, ZL; Chen, BY; Chen, X; He, J; He, QY; Lin, JT; Su, N; Xiao, Y; Yan, XX; Yang, M, 2007) |
| "Sixty-four patients with persistent asthma receiving 200 to 800 microg of fluticasone propionate daily were enrolled in this switchover study." | 5.12 | Addition of transdermal or inhaled long-acting Beta2-agonists in adult asthmatic patients treated with inhaled corticosteroids: switchover study from tulobuterol patch to salmeterol dry powder inhaler. ( Kita, H; Kobayashi, Y; Kudou, M; Yasuba, H, 2007) |
| "To compare the efficacy and tolerability of nebulized adrenaline and terbutaline in acute severe asthma." | 5.11 | Comparison of nebulized epinephrine and terbutaline in patients with acute severe asthma: a controlled trial. ( Adoun, M; Doré, P; Frat, JP; Godet, C; Robert, R; Rouffineau, J, 2004) |
| "5 microg) via Turbuhaler) are at least as safe as and associated with less systemic effects than multiple inhalations of the clinically equipotent dose of terbutaline (500 microg) in children with asthma." | 5.11 | Cumulative high doses of inhaled formoterol have less systemic effects in asthmatic children 6-11 years-old than cumulative high doses of inhaled terbutaline. ( Agertoft, L; Bengtsson, T; Johannes-Hellberg, I; Kaae, R; Nordvall, SL; Pedersen, S; Pedroletti, C; Rosenborg, J, 2004) |
| "To compare the clinical efficacy and side effects of terbutaline and salbutamol administered by metered dose inhaler and holding chamber in the mild to moderate acute exacerbations of asthma in children." | 5.11 | Comparison of terbutaline and salbutamol inhalation in children with mild or moderate acute exacerbation of asthma. ( Chandra, P; Kabra, SK; Lodha, R; Paliwal, L, 2004) |
| "MCC was measured at baseline and in response to 1 mg terbutaline (or placebo) on three visits over 80 min in 16 asthmatics (52+/-13 years of age)." | 5.11 | Mucociliary clearance in patients with chronic asthma: effects of beta agonists. ( Anderson, SD; Daviskas, E; Eberl, S; Seale, JP; Shaw, J; Yang, IA; Young, IH, 2005) |
| "5 mg terbutaline, both by Turbuhaler and used as needed, in addition to regular formoterol in moderate asthma." | 5.10 | Safety of formoterol by Turbuhaler as reliever medication compared with terbutaline in moderate asthma. ( Böszörményi, NG; Ind, PW; Pietinalho, A; Selroos, O; Shiner, RJ; Soliman, S; Villasante, C, 2002) |
| "Our aim was to confirm that sputum and serum ECP measurements would provide a more sensitive indicator of responses to asthma treatment than eosinophil counts per se, in a randomized, placebo-controlled, crossover study of terbutaline, budesonide, and their combination in patients with chronic persistent asthma." | 5.10 | Eosinophils and eosinophilic cationic protein in induced sputum and blood: effects of budesonide and terbutaline treatment. ( Aldridge, RE; Cowant, JO; Frampton, CM; Hancox, RJ; Taylor, DR; Town, GI, 2002) |
| " The effects of inhaling terbutaline in combination with mannitol on MCC were investigated in nine healthy (aged 19+/-1 yrs) and 11 mild (aged 21+/-4 yrs) asthmatic subjects." | 5.10 | Effects of terbutaline in combination with mannitol on mucociliary clearance. ( Anderson, SD; Chan, HK; Daviskas, E; Eberl, S; Seale, JP; Young, IH, 2002) |
| "To compare the efficacy of terbutaline sulphate delivered via Turbuhaler with a pressurised metered dose inhaler (pMDI) connected to Nebuhaler spacer in a population of asthmatic children presenting to emergency departments because of an acute episode of asthma." | 5.10 | Comparative efficacy of terbutaline sulphate delivered by Turbuhaler dry powder inhaler or pressurised metered dose inhaler with Nebuhaler spacer in children during an acute asthmatic episode. ( Cummins-McManus, B; Drblik, S; Gaudreault, P; Haddon, J; Lapierre, G; Lee, J; Spier, S; Thivierge, R; Turgeon, J; Verdy, I, 2003) |
| "We examined whether a combination of glucocorticoids and beta-agonists inhaled by asthmatics had an influence on the metabolism of L-arginine, an amino acid involved in the production of urea, creatinine, and NO that is known to play a significant role in asthma." | 5.10 | Creatininuria in asthmatic children treated with a combination of glucocorticoid and beta-agonist. ( Ferrières, J; Giroux, M, 2003) |
| "To assess the bronchodilatory effect of loratadine in children with mild-to-moderate asthma and to determine whether loratadine interacts with terbutaline." | 5.10 | The bronchodilatory effects of loratadine, terbutaline, and both together versus placebo in childhood asthma. ( Baki, A; Orhan, F, 2003) |
| " Thirty-eight patients with stable mild to moderate asthma and receiving inhaled corticosteroids were randomized in a parallel group, double-blind, double-dummy fashion to receive 2 weeks of treatment with either formoterol (12 microg once daily, 6 microg twice daily or 24 microg twice daily) or terbutaline (500 microg four times daily)." | 5.09 | Beta2-adrenoceptor polymorphism and bronchoprotective sensitivity with regular short- and long-acting beta2-agonist therapy. ( Aziz, I; Hall, IP; Lipworth, BJ; Tan, KS; Wheatley, A, 1999) |
| "Following a run in period, 33 subjects with asthma taking regular beta agonists were converted to an equivalent dose of terbutaline via a Turbohaler." | 5.09 | Randomised placebo controlled trial of beta agonist dose reduction in asthma. ( Harrison, TW; Oborne, J; Tattersfield, AE; Wilding, PJ, 1999) |
| "Sixty one subjects with mild to moderate asthma were randomised to a double blind crossover comparison of inhaled budesonide (200-400 microg twice daily), terbutaline (500-1000 microg four times daily), combined treatment, and placebo." | 5.09 | Randomised trial of an inhaled beta2 agonist, inhaled corticosteroid and their combination in the treatment of asthma. ( Cowan, JO; Flannery, EM; Hancox, RJ; Herbison, GP; McLachlan, CR; Taylor, DR; Wong, CS, 1999) |
| "To investigate dose proportionality, dosing frequency, and ethnic aspects of the pharmacokinetics of bambuterol in asthmatic children, and to discuss the relationship with previous observations in adults." | 5.09 | Pharmacokinetics of bambuterol during oral administration to asthmatic children. ( Ahlström, H; Alvero, J; Alvero, R; Espos, R; Fajutrao, L; Herrera, J; Kjellman, B; Kubista, J; Laxmyr, L; Leviste, C; Meyer, P; Nyberg, L; Oldaeus, G; Olsson, H; Rosenborg, J; Siricururat, A; Vichyanond, P; Weibull, E; Wettrell, G; Wong, E, 1999) |
| " We undertook a randomized, crossover study to investigate the effects of 6 wk of treatment with regular terbutaline (1 mg four times a day), regular budesonide (400 microg twice a day), combined treatment, and placebo in subjects with mild to moderate asthma." | 5.09 | Effects of terbutaline and budesonide on sputum cells and bronchial hyperresponsiveness in asthma. ( Aldridge, RE; Cowan, JO; Frampton, CM; Hancox, RJ; Robin Taylor, D; Town, GI; Winn, MC, 2000) |
| " We have recently completed a study of the regular terbutaline and budesonide treatment in asthma." | 5.09 | Bronchodilator tolerance and rebound bronchoconstriction during regular inhaled beta-agonist treatment. ( Cowan, JO; Flannery, EM; Hancox, RJ; Herbison, GP; McLachlan, CR; Taylor, DR, 2000) |
| "5 microg provided better asthma control than terbutaline 0." | 5.09 | Comparison of formoterol and terbutaline for as-needed treatment of asthma: a randomised trial. ( Eivindson, A; Ekström, T; Löfdahl, CG; Postma, DS; Rasidakis, A; Schreurs, AG; Tattersfield, AE, 2001) |
| "Sixty children who have experienced an acute exacerbation of asthma unresponsive to home management with regular use of inhaled beta2 mimetics, yet not severe enough to hospitalize, were randomized to be treated with either high-dose inhaled budesonide (1,600 microg daily) or oral methylprednisolone (1 mg/kg daily) plus medium-dose inhaled budesonide (800 microg daily, both in addition to inhaled terbutaline, 2,000 microg daily)." | 5.09 | The effectiveness of high-dose inhaled budesonide therapy in the treatment of acute asthma exacerbations in children. ( Bahçeciler, NN; Barlan, IB; Müjdat Başaran, M; Nuhoğlu, Y, 2001) |
| "To determine the benefit of inhaled high dose budesonide combined with terbutaline in patients with severe asthma at high altitude." | 5.09 | [Inhaled budesonide for severe asthma at high altitude]. ( Feng, E; Suo, Y; Yang, S, 2000) |
| "This study aimed to compare the duration of protection against exercise-induced bronchoconstriction (EIB) after inhalation of formoterol (Oxis) Turbuhaler with that of terbutaline Turbuhaler and placebo Turbuhaler in asthmatic patients treated regularly with formoterol Turbuhaler 9 microg b." | 5.09 | Protection against cold air and exercise-induced bronchoconstriction while on regular treatment with Oxis. ( Ankerst, J; Johansson, A; Palmqvist, M; Persson, G; Schaanning, J; Schwabe, G; Vilsvik, J, 2001) |
| "We investigated the relationship between pulmonary deposition of terbutaline and bronchoprotection against methacholine and histamine with the Turbuhaler (AstraZeneca, Lund, Sweden) and a pressurized metered dose inhaler (pMDI) in 13 asthmatic patients." | 5.09 | Lung deposition and protective effect of terbutaline delivered from pressurized metered-dose inhalers and the Turbuhaler in asthmatic individuals. ( Borgström, L; Derom, E; Löfroos, AB; Pauwels, R; Van Schoor, J, 2001) |
| "The aim of this study was to evaluate if continuous treatment with budesonide or salmeterol influences the bronchodilator response to terbutaline in children with asthma; 23 children, aged 7 to 16 years (mean = 11 years), with mild asthma were treated with inhaled budesonide 100 micrograms b." | 5.08 | Influence of budesonide on the response to inhaled terbutaline in children with mild asthma. ( Agertoft, L; Fuglsang, G; Pedersen, S; Vikre-Jørgensen, J, 1995) |
| "The aim of the study was to compare the efficacy, tolerability and patient acceptability of bambuterol (Bambec) against controlled release (CR) salbutamol (Volmax) in the treatment of nocturnal asthma." | 5.08 | Comparison of the efficacy, tolerability and patient acceptability of once-daily bambuterol tablets against twice-daily controlled release salbutamol in nocturnal asthma. ACROBATICS Research Group. ( Ayres, JG; Gunn, SD; McConchie, SM, 1995) |
| "One hundred and eleven children with acute asthma were studied to compare delivery of terbutaline by either a metered dose inhaler (MDI) with a valved holding chamber or a nebuliser driven by air." | 5.08 | Metered dose inhaler and nebuliser in acute asthma. ( Hsieh, KH; Lin, YZ, 1995) |
| "Bambuterol is a new long-acting oral bronchodilator for once daily use in patients with asthma." | 5.08 | One month treatment with the once daily oral beta 2-agonist bambuterol in asthmatic patients. ( Baas, A; Knight, A; Larsen, B; Olsson, H; Persson, G, 1995) |
| "Once-daily morning (7 AM) vs evening (10 PM) administration of the terbutaline prodrug bambuterol (20-mg tablet dose) was investigated in a double-blind, cross-over, randomized, and placebo-controlled study involving 29 diurnally active patients with asthma." | 5.08 | Bambuterol in the treatment of asthma. A placebo-controlled comparison of once-daily morning vs evening administration. ( D'Alonzo, GE; Feldman, S; Gnosspelius, Y; Karlsson, K; Smolensky, MH, 1995) |
| "This was a 4-week, open-label, parallel-group study designed to compare the efficacy and safety of the long-acting inhaled bronchodilator, salmeterol, with the established inhaled bronchodilator, terbutaline, in the treatment of patients with mild to moderate asthma." | 5.08 | A 4-week comparison of salmeterol and terbutaline in adult asthma. ( Hermansson, BA; Jenkins, RJ, 1995) |
| "An open, randomized, parallel-group study was conducted to investigate whether asthmatic patients, considered adequately treated with a corticosteroid and/or short-acting beta 2-agonist via pressurized metered-dose inhaler (pMDI), could be transferred to a corresponding nominal dose of budesonide and/or terbutaline via Turbuhaler, an inspiratory flow-driven multidose dry powder inhaler (Astra Draco; Lund, Sweden), without a decrease in the effect of treatment." | 5.08 | A 1-year comparison of turbuhaler vs pressurized metered-dose inhaler in asthmatic patients. ( Bukoski, M; Camus, P; Hargreave, FE; Pauwels, RA; Ståhl, E, 1996) |
| "0 mg of terbutaline, administered via Turbuhaler, in children with mild to moderate asthma, and to register peak inspiratory flow rates through Turbuhaler (PIFTBH)." | 5.08 | Dose response to inhaled terbutaline powder and peak inspiratory flow through Turbuhaler in children with mild to moderate asthma. ( Ribeiro, LB; Sandahl, G; Ståhl, E, 1996) |
| "Ninety children with acute asthma, equally divided into two study groups, were studied to compare the efficacy and safety of nebulized terbutaline with injected epinephrine in the treatment of acute exacerbation." | 5.08 | Terbutaline nebulization and epinephrine injection in treating acute asthmatic children. ( Chang, LF; Chu, CY; Hsieh, KH; Lin, YZ, 1996) |
| " The bronchodilator, cardiovascular, and tremorigenic responses following administration of salbutamol (SAL), terbutaline (TER) and fenoterol (FEN) by closed-port intermittent nebulization were compared for a period of 8 hr." | 5.08 | Efficacy and side effects of beta 2-agonists by inhaled route in acute asthma in children: comparison of salbutamol, terbutaline, and fenoterol. ( Naspitz, CK; Scalabrin, DM; Solé, D, 1996) |
| "Sixteen subjects with mild stable asthma inhaled budesonide 800 micrograms twice daily for two periods of 14 days with terbutaline 1000 micrograms three times daily or placebo in a double blind crossover fashion." | 5.08 | Effect of regular terbutaline on the airway response to inhaled budesonide. ( Bennett, JA; Clark, MM; Oborne, J; Tattersfield, AE; Wilding, PJ, 1996) |
| "The response to histamine and AMP challenges and the protection afforded by terbutaline (500 micrograms) against these two challenges was measured on two occasions two weeks apart in 20 subjects with asthma (19 completed the study)." | 5.08 | Adenosine monophosphate and histamine induced bronchoconstriction: repeatability and protection by terbutaline. ( Egbagbe, E; Pavord, ID; Tattersfield, AE; Thompson-Coon, J; Wilding, P, 1997) |
| "This study was designed to compare the bronchodilatatory effect of terbutaline inhaled through Turbuhaler (TH) or pressurized metered-dose inhaler (pMDI) in young asthmatics, and to assess the possible relationship between patients' inspiratory capacity and bronchodilatation for both devices." | 5.08 | Influence of inspiratory capacity on bronchodilatation via Turbuhaler or pressurized metered-dose inhaler in asthmatic children: a comparison. ( Hirsch, T; Koch, R; Leupold, W; Peter-Kern, M, 1997) |
| " On two occasions, seven asthmatic subjects were administered terbutaline or its vehicle by intravenous infusion 7 h after inhaled allergen, at which point the forced expiratory volume in 1 s was 57% of baseline." | 5.08 | Rapid reversibility of the allergen-induced pulmonary late-phase reaction by an intravenous beta2-agonist. ( Peebles, RS; Permutt, S; Togias, A, 1998) |
| "Inhaled glucocorticosteroids in a single dose had no significant effect in restoring terbutaline induced loss of bronchoprotection, implying that mast cell beta 2 adrenoceptor sensitivity is not restored by a single dose of an inhaled glucocorticosteroid in asthma." | 5.08 | Effect of an inhaled glucocorticosteroid on mast cell and smooth muscle beta 2 adrenergic tolerance in mild asthma. ( Barnes, PJ; Worsdell, M; Yates, DH, 1998) |
| "In a randomized, parallel group, double-blind study at two centers, patients with stable asthma of mild to moderate severity who were treated with inhaled corticosteroids were treated with formoterol 6 micrograms twice daily, 24 micrograms twice daily, 12 micrograms once daily; terbutaline 500 micrograms four times daily; or placebo." | 5.08 | Effects of treatment with formoterol on bronchoprotection against methacholine. ( Aiken, T; Baker, R; Devlin, M; Hendrick, D; Lipworth, B; Tan, S, 1998) |
| "The aim of this study was to investigate whether regular treatment with inhaled salmeterol modifies the dose-response curve to the inhaled short-acting beta2-agonist terbutaline or affects the concentration of nitric oxide (NO) in exhaled air of children with asthma." | 5.08 | Effect of salmeterol treatment on nitric oxide level in exhaled air and dose-response to terbutaline in children with mild asthma. ( Agertoft, L; Fuglsang, G; Pedersen, S; Vikre-Jørgensen, J, 1998) |
| "Eight patients with stable asthma weaned off beta2-agonist therapy were studied in a randomized, double-blinded, placebo-controlled study utilizing aerosolized terbutaline, 400 microg q6h." | 5.08 | Hemodynamic, cardiac, and electrolyte effects of low-dose aerosolized terbutaline sulfate in asthmatic patients. ( Braden, GL; Bria, WF; Germain, MJ; Hafer, JG; Mulhern, JG, 1998) |
| "Subcutaneous administration of epinephrine is as effective as terbutaline in treating acute attack of asthma in infants." | 5.08 | [Comparison of the effect of subcutaneous injection of adrenaline and terbutaline in asthma crisis in infants]. ( Khaldi, F; Salem, N, 1998) |
| " On three consecutive days, at the same time of day, 20 adult patients with chronic asthma inhaled two puffs of terbutaline sulphate (0." | 5.07 | Improvement of inhaler efficacy by home-made spacer. ( Janvitayanuchit, S; Sritara, P, 1993) |
| "Patients with chronic obstructive diseases of the lungs and bronchial asthma were treated with terbutaline sulfate in combination with cefotaxime." | 5.07 | [Effectiveness of comprehensive therapy of broncho-obstructive syndrome]. ( Bormotova, MS; Sokolova, VI; Zavolovskaia, LI, 1994) |
| "Ease of handling as well as efficacy of a new terbutaline inhalation device--Bricanyl Turbuhaler--were evaluated among eighty-six Asian children with mild to moderate asthma with a mean age of 8." | 5.07 | Ease of handling and efficacy of Bricanyl Turbuhaler in Asian asthmatic children. ( Omar, AH; Phanichyakarn, P; Tam, A; Vichyanond, P; Wong, E, 1994) |
| "The aim of the multicenter, randomized, double-blind, double-dummy, parallel-group clinical trial with a 2-week treatment period was to compare the efficacy and safety of salmeterol (50 micrograms twice daily) with slow-release (SR) terbutaline (5 mg orally, twice daily) in nocturnal asthma." | 5.07 | Salmeterol compared with slow-release terbutaline in nocturnal asthma. A multicenter, randomized, double-blind, double-dummy, sequential clinical trial. French Multicenter Study Group. ( Bertin, L; Brambilla, C; Chastang, C; Georges, D, 1994) |
| "In a randomized, double-blind, placebo-controlled study, we investigated the protective effects of ipratropium bromide 160 micrograms and 320 micrograms and terbutaline 500 micrograms on ultrasonically nebulized distilled water (UNDW)-induced bronchoconstriction in nine stable asthmatic patients." | 5.07 | The protective effects of ipratropium bromide and terbutaline on distilled water-induced bronchoconstriction. ( Festen, J; Groot, CA; Lammers, JW; van Herwaarden, CL, 1994) |
| "In a previous study, we found that two years of treatment with an inhaled corticosteroid, budesonide, was more effective than treatment with an inhaled beta 2-agonist, terbutaline, in patients with newly diagnosed, generally mild asthma." | 5.07 | Effects of reducing or discontinuing inhaled budesonide in patients with mild asthma. ( Haahtela, T; Järvinen, M; Kava, T; Kiviranta, K; Koskinen, S; Lehtonen, K; Nikander, K; Persson, T; Selroos, O; Sovijärvi, A, 1994) |
| " In order to investigate the possibility of replacing established treatment modalities with bambuterol once daily, we wanted to compare the bronchodilating and tremorogenic effects of bambuterol, 10 mg once daily, and terbutaline, 5 mg controlled-release (CR) tablets twice daily." | 5.07 | Therapeutic equivalence between bambuterol, 10 mg once daily, and terbutaline controlled release, 5 mg twice daily, in mild to moderate asthma. ( Fugleholm, AM; Ibsen, TB; Laxmyr, L; Svendsen, UG, 1993) |
| "Twenty seven adults and 20 children with previously diagnosed stable asthma, using a salbutamol pressurized metered dose inhaler (P-MDI) and living in Cairns, Townsville and Southport, Queensland, Australia participated in a randomized, open-label cross-over comparison of terbutaline administered via Turbuhaler and salbutamol administered via P-MDI." | 5.07 | A multicentre comparison of the efficacy of terbutaline Turbuhaler and salbutamol pressurized metered dose inhaler in hot, humid regions. ( Buchanan, PR; Lindsay, DA; Russell, NL; Shellshear, ID; Thompson, JE; Warnock, TH, 1994) |
| "We compared the bronchodilator response of terbutaline delivered either by a dry powder inhaler, the Turbuhaler, or by a metered-dose inhaler attached to a Nebuhaler inhaler in 10 children with stable asthma who were 3 to 6 years of age." | 5.07 | Comparison of inhaled terbutaline administered by either the Turbuhaler dry powder inhaler or a metered-dose inhaler with spacer in preschool children with asthma. ( Drblik, SP; Laberge, S; Spier, S; Turgeon, JP, 1994) |
| "Bambuterol was compared with placebo in 28 patients with nocturnal asthma in a randomized, double-blind cross-over study." | 5.07 | Bambuterol: effective in nocturnal asthma. ( Chookang, JY; Hassan, WU; Morrison, JF; Ning, AC; O'Reilly, JF; Pearson, SB; Petrie, GR; Shneerson, JM; Tang, OT; Turbitt, ML, 1993) |
| " In a double blind, randomised, crossover study the effect of preservatives in determining the airway responses to 5 mg of terbutaline was studied in a group of 21 atopic asthmatic patients." | 5.07 | Effect of preservative on the efficacy of terbutaline nebuliser solution in atopic asthma. ( Chan, CH; Lai, CK, 1993) |
| "To evaluate the influence of inhaled terbutaline and positive expiratory pressure (PEP) on airway resistance (Raw) and functional residual capacity (FRC) in bronchial asthma." | 5.07 | Inhaled beta 2-agonist and positive expiratory pressure in bronchial asthma. Influence on airway resistance and functional residual capacity. ( Christensen, EF; Dahl, R; Jensen, LW; Nørregaard, O, 1993) |
| "A new long-acting bronchodilator prodrug, bambuterol hydrochloride, was tested in a randomized, crossover, and double-blind study in elderly asthmatic patients (aged 64 to 82 years)." | 5.07 | A placebo-controlled dose-finding study with bambuterol in elderly patients with asthma. ( Alexander, M; Aoki, FY; Grossman, RF; Knight, A; Sitar, DS; Soliman, S; Warren, CP, 1993) |
| "The effect of oral terbutaline (controlled-release [CR] tablets) was compared with that of inhaled ipratropium bromide (aerosol) in 21 patients with nocturnal asthma." | 5.07 | Terbutaline controlled-release tablets and ipratropium aerosol in nocturnal asthma. ( Elo, J; Mansury, L; Tammivaara, R, 1993) |
| "Effects of the inhaled corticosteroid budesonide and the oral beta-agonist bambuterol on the nocturnal worsening of asthma were studied in patients with allergic asthma with a circadian peak expiratory flow variation greater than or equal to 15% (group 1, n = 8) and less than 15% (group 2, n = 9)." | 5.07 | Effects of budesonide and bambuterol on circadian variation of airway responsiveness and nocturnal symptoms of asthma. ( Auffarth, B; Koëter, GH; Postma, DS; Tammeling, EP; Teengs, JP; Wempe, JB, 1992) |
| "We observed tolerance to the nonbronchodilator actions of the inhaled beta 2-agonist terbutaline in patients with mild asthma, an effect that may be more pronounced in mast cells than in bronchial smooth muscle." | 5.07 | Tolerance to the nonbronchodilator effects of inhaled beta 2-agonists in asthma. ( Aikman, SL; Barnes, PJ; O'Connor, BJ, 1992) |
| " Thirty six adults with chronic asthma requiring beta-agonists four times daily were treated with terbutaline 500 micrograms via T and salbutamol 400 micrograms via D four times daily, each period lasting four weeks." | 5.07 | Breath-actuated inhalers in chronic asthma: comparison of Diskhaler and Turbohaler for delivery of beta-agonists. ( Armstrong, S; Brown, PH; Crompton, GK; Lenney, J; Ning, AC, 1992) |
| "We compared the changes in peak expiratory flow rate (PEFR), plasma potassium and plasma glucose during and after an infusion of the beta 2-agonist, terbutaline, in seven asthmatic subjects." | 5.07 | Pilot study to compare the bronchodilator and metabolic responses to terbutaline infusion in seven asthmatic subjects--are they correlated? ( Haffner, CA; Holder, R; Hughes, B; Kendall, MJ, 1992) |
| "In a double-blind cross-over study comparing the duration of action of 12 micrograms and 24 micrograms formoterol, 500 micrograms terbutaline and placebo, lung function tests were performed in 12 never-smokers with non-allergic bronchial asthma." | 5.07 | Effect of inhaled formoterol versus terbutaline on respiratory function in moderate bronchial asthma. ( Boman, G; Hedenström, H; Melander, B; Wåhlander, L; Wegener, T, 1992) |
| "Disposition and efficacy of bambuterol were studied in 10 younger (20 to 37 years) and 10 older (69 to 76 years) patients with asthma (nine men and 11 women) at steady state, after single daily doses of 20 mg (50 mumol) for 1 week." | 5.07 | Pharmacokinetics and pharmacodynamics of bambuterol, a long-acting bronchodilator pro-drug of terbutaline, in young and elderly patients with asthma. ( Aoki, FY; Sitar, DS; Warren, CP, 1992) |
| "We have measured the plasma levels of salbutamol, terbutaline and theophylline in 140 patients (70 men, mean age 57 yrs) arriving for emergency treatment with severe acute asthma." | 5.07 | Bronchodilator intake and plasma levels on admission for severe acute asthma. ( Boe, J; Boman, G; Janson, C; Mossberg, B; Svedmyr, N, 1992) |
| "We compared the effect of an inhaled corticosteroid, budesonide, and an inhaled beta 2-agonist, terbutaline, on clinical symptoms, lung function, and airway inflammation in 14 adult patients with newly diagnosed asthma." | 5.07 | A comparative study of the effects of an inhaled corticosteroid, budesonide, and a beta 2-agonist, terbutaline, on airway inflammation in newly diagnosed asthma: a randomized, double-blind, parallel-group controlled trial. ( Haahtela, T; Laitinen, A; Laitinen, LA, 1992) |
| "The effect of different methods of administration of inhaled terbutaline on mucociliary clearance and forced expiratory volume in one second (FEV1) was assessed in 10 patients with asthma and 10 healthy subjects." | 5.07 | Effect of terbutaline on mucociliary clearance in asthmatic and healthy subjects after inhalation from a pressurised inhaler and a dry powder inhaler. ( Groth, S; Hermansen, F; Lange, P; Mortensen, J, 1991) |
| "Our study investigated the differential effects of continuous or unequal day-night terbutaline dosing on circadian bronchial patency, heart rate, and arterial pressure in severe acute asthma." | 5.07 | Unequal day-night terbutaline i.v. dosing in acute severe asthma: effect on nocturnal bronchial patency, heart rate, and arterial pressure. ( Arnaud, A; Bruguerolle, B; Lagier, F; Leonardelli, M; Orlando, JP; Philip-Joet, F; Pierson, F; Reynaud, M; Vervloet, D, 1991) |
| "The effects of treatment with budesonide (200 micrograms twice daily) and terbutaline (500 micrograms four times daily) has been compared with the effects of placebo and terbutaline in 27 children with mild asthma, aged 7-14 years, in a double blind, randomised placebo controlled study over eight weeks." | 5.07 | Budesonide and terbutaline or terbutaline alone in children with mild asthma: effects on bronchial hyperresponsiveness and diurnal variation in peak flow. ( Gerritsen, J; Knol, K; Koëter, GH; Krouwels, FH; van Aalderen, WM; Waalkens, HJ, 1991) |
| "Bambuterol, a carbamate prodrug of terbutaline as a 5, 10, or 20-mg tablet, was given once every evening to patients with asthma in a randomized double-blind crossover study." | 5.07 | Bambuterol: a new long acting bronchodilating prodrug. ( Holthe, S; Kvelstad, G; Langaker, O; Persson, G; Ringdal, N; Schaanning, J; Soliman, S; Svensson, K; Vilsvik, JS, 1991) |
| "Antiinflammatory therapy with inhaled budesonide is an effective first-line treatment for patients with newly detected, mild asthma, and it is superior to the use of terbutaline in such patients." | 5.07 | Comparison of a beta 2-agonist, terbutaline, with an inhaled corticosteroid, budesonide, in newly detected asthma. ( Haahtela, T; Järvinen, M; Kava, T; Kiviranta, K; Koskinen, S; Lehtonen, K; Nikander, K; Persson, T; Reinikainen, K; Selroos, O, 1991) |
| " The effects of a new long-acting inhaled beta 2-adrenoceptor agonist aerosol formoterol (12 micrograms), on FEV1, and on methacholine-induced bronchoconstriction, were compared with those of terbutaline (250 micrograms) and placebo in 12 midly asthmatic subjects." | 5.06 | Effect of formoterol, a long-lasting beta 2-adrenoceptor agonist, against methacholine-induced bronchoconstriction. ( Barnes, PJ; Chung, KF; Nichol, GM; Nix, A; Robson, A, 1990) |
| "The airway response and cardiovascular and hypokalaemic effects of fenoterol, salbutamol, and terbutaline given in multiples of standard doses from metered-dose inhalers were studied in ten patients with mild asthma." | 5.06 | Bronchodilator, cardiovascular, and hypokalaemic effects of fenoterol, salbutamol, and terbutaline in asthma. ( Britton, JR; Pavord, ID; Tattersfield, AE; Williams, J; Wong, CS, 1990) |
| "Nine adult asthmatics with a history of nocturnal symptoms and with morning dips in peak expiratory flow (PEF) were treated for 10-14 days with 24-h controlled-release preparation of theophylline (Th), or a controlled-release preparation of terbutaline (Te), in a double-blind cross-over experiment." | 5.06 | Nocturnal oxygen saturation and body movement in asthmatics treated with controlled-release preparations of theophylline or terbutaline. ( Brander, PE; Hakulinen, A; Poppius, H; Salmi, T; Sovijärvi, AR, 1990) |
| "The effects on baseline ventilation as well as beta 2-receptor stimulant-induced bronchodilation and tremor of atenolol and dilevalol, a beta-blocking agent with non-selective beta-antagonistic properties and intrinsic activity on the beta 2-receptor were evaluated in 8 patients with stable asthma." | 5.06 | Effects of dilevalol, a beta-adrenoceptor antagonist with intrinsic sympathetic activity in asthmatic patients. ( Hedner, J; Lemne, C; Svedmyr, N; Ullman, A, 1989) |
| "Eighteen patients (nine asthmatic patients and nine with poorly reversible airflow obstruction) with stable, severe chronic airflow obstruction, completed a four-week randomized, doubled-blind, placebo-control, crossover trial comparing the acute and chronic effects of terbutaline administered by metered-dose inhaler (MDI) and nebulizer (NEB)." | 5.06 | Comparison of outpatient nebulized vs metered dose inhaler terbutaline in chronic airflow obstruction. ( Copland, JM; McDonald, CF; Mestitz, H, 1989) |
| "A study was carried out in 8 patients with chronic stable bronchial asthma to compare the bronchodilator response with terbutaline, administered by a recently developed powder inhalation system ('Turbuhaler') and equipotent doses of salbutamol administered by a widely used powder inhaler ('Rotahaler')." | 5.06 | Dose-effect relationship of terbutaline using a multi-dose powder inhalation system ('Turbuhaler') and salbutamol administered by powder inhalation ('Rotahaler') in asthmatics. ( Bogaard, JM; Slingerland, R; Verbraak, AF, 1989) |
| "The purpose of this study was to compare effect of treatment with an oral long-acting beta 2-agonist (sustained-release terbutaline, Bricanyl depot), an inhaled steroid (budesonide, Pulmicort), and the combined treatment in patients with nocturnal asthma." | 5.06 | Nocturnal asthma: effect of treatment with oral sustained-release terbutaline, inhaled budesonide, and the two in combination. ( Dahl, R; Hägglöf, B; Pedersen, B, 1989) |
| "To evaluate the long-term effects of slow-release formulations of theophylline and terbutaline on pulmonary function, clinical symptoms, and side effects, 24 children with stable and moderately severe perennial asthma participated in a prospective double-blind cross-over study." | 5.06 | Slow-release terbutaline and theophylline for the long-term therapy of children with asthma: a Latin square and factorial study of drug effects and interactions. ( Chow, OK; Fung, KP, 1989) |
| "We compared the use of terbutaline sulphate that was delivered by a nebulizer with its delivery by a Nebuhaler at two dose levels in 27 children (nine children per group) of between three and six years of age with acute asthma." | 5.06 | Comparative efficacy of terbutaline administered by Nebuhaler and by nebulizer in young children with acute asthma. ( Hopkins, J; Pendergast, J; Timms, B; Van Asperen, PP, 1989) |
| " 57 children with asthma participated in this clinical trial to compare the clinical effect and acceptance of terbutaline sulphate via Turbuhaler with that of metered dose inhaler (MDI)." | 5.06 | A double-blind comparison between a new multidose powder inhaler (Turbuhaler) and metered dose inhaler in children with asthma. ( Ahlström, H; Hultquist, C; Kjellman, NI; Malmqvist, LA; Melin, S; Svenonius, E, 1989) |
| "A randomized clinical trial comparing subcutaneous epinephrine and terbutaline injections was conducted in asthmatic children at The Methodist Hospital, Brooklyn, New York." | 5.06 | Comparison between epinephrine and terbutaline injections in the acute management of asthma. ( Battista, CJ; Nangia, BS; Victoria, MS, 1989) |
| "25 mg terbutaline from a Turbuhaler was assessed, in a double-blind cross-over study, of 14 asthmatic children aged 8-14 yrs (mean 11." | 5.06 | Optimal inhalation technique with terbutaline Turbuhaler. ( Hansen, OR; Pedersen, S, 1989) |
| "Thirteen children with asthma were treated with cumulative doses of terbutaline delivered as a pressurized aerosol and from a new multidose powder inhaler (Turbuhaler) in a randomized cross-over dose-response study." | 5.06 | Comparison of a new multidose powder inhaler with a pressurized aerosol in children with asthma. ( Fuglsang, G; Pedersen, S, 1989) |
| "The aim of this study was to evaluate the efficacy, safety and preference of pre-school children with regard to two different devices for treatment of bronchial asthma with terbutaline." | 5.06 | Treatment of asthma in pre-school children with inhalation of terbutaline in Turbuhaler compared with Nebuhaler. ( Ahlström, H; Svenonius, E; Svensson, M, 1989) |
| "In a group of ten patients with chronic asthmatic bronchitis, the effect of monotherapy with theophylline and terbutaline and the combination of both drugs, as sustained-release tablets, was compared to placebo, in a double-blind cross-over, triple dummy at random study." | 5.06 | Combination therapy of theophylline and terbutaline as sustained-release preparations in patients with asthmatic bronchitis. ( Fokkens, JK; Hamelink, MJ; Kreukniet, J; Maes, RA; van der Vet, AP; van Drost, RH, 1987) |
| "The beta 2-adrenoceptor mediated effects on ventilatory capacity, forced expiratory volume in one second (FEV1), forced ventilatory capacity (FVC), heart rate, and skeletal muscle tremor of a new controlled-release (CR) formulation of metoprolol, 100 mg and 200 mg, and of atenolol tablets, 100 mg, were studied in eight asthmatic patients." | 5.06 | Controlled-release metoprolol compared with atenolol in asthmatic patients: interaction with terbutaline. ( Dahlöf, C; Löfdahl, CG; Olofsson, B; Svedmyr, N; Westergren, G, 1988) |
| "52 severely ill asthmatic patients requiring acute admission to hospital entered a double-blind placebo-controlled trial to determine whether intravenous hydrocortisone given in addition to high-dose oral prednisolone and standard bronchodilator therapy accelerated recovery." | 5.06 | Need for intravenous hydrocortisone in addition to oral prednisolone in patients admitted to hospital with severe asthma without ventilatory failure. ( Ali, NJ; Harrison, BD; Hart, GJ; Robinson, AA; Stokes, TC; Vaughan, DA, 1986) |
| "Fifteen asthmatic patients participated in a dose-ranging study using tulobuterol syrup in single doses of 10 to 60 mcg/kg." | 5.06 | Tulobuterol in childhood asthma: single dose ranging and repeated oral dose comparative studies. ( Javier, MA; Noche, ML, 1986) |
| "The effects of single oral doses of atenolol 50 mg and xamoterol 200 mg (a recently developed partial beta 1-adrenoceptor agonist) on lung function, heart rate and blood pressure were investigated in 11 patients with asthma." | 5.06 | A comparative study on the ventilatory and haemodynamic effects of xamoterol and atenolol in asthmatic patients. ( Folgering, HT; Lammers, JW; Müller, ME; van Herwaarden, CL, 1986) |
| "The effect of long-term treatment with theophylline was studied in 20 chronic asthmatic patients receiving oral and inhaled beta 2-agonists." | 5.06 | Theophylline in maintenance treatment of chronic asthma: concentration-dependent additional effect to beta 2-agonist therapy. ( Billing, B; Dahlqvist, R; Hörnblad, Y; Leideman, T; Ripe, E; Skareke, L, 1987) |
| " Subjects with mild asthma were investigated to determine the course of change in bronchial responsiveness, measured as the provocative dose (PD20) of histamine that caused a 20% fall in forced expiratory volume in 1 s after short-term and longer term treatment with an inhaled beta-agonist." | 5.06 | Rebound increase in bronchial responsiveness after treatment with inhaled terbutaline. ( Britton, JR; Higgins, BG; Knox, AJ; Tattersfield, AE; Vathenen, AS, 1988) |
| "Nebulization treatment of acute asthma with terbutaline and ipratropium bromide, given either separately with a 30-minute interval or combined as single inhalation, was compared with injection treatment with a combination of terbutaline given subcutaneously and theophylline given intravenously." | 5.06 | Nebulization versus injection in ambulatory treatment of acute asthma: a comparative study. ( Herala, M; Janson, C; Sjögren, I, 1988) |
| "In a controlled, open cross-over study 15 asthmatic children received increasing doses of terbutaline (0." | 5.06 | Cumulative dose response relationship of terbutaline delivered by three different inhalers. ( Fuglsang, G; Pedersen, S, 1988) |
| "Twenty-two asthmatics received bambuterol solution, a terbutaline pro-drug, once every evening." | 5.06 | Bambuterol: clinical effects of three doses of bambuterol once daily in asthmatic patients. ( Clemmensen, IH; Laursen, LC; Pedersen, BK; Ravn, S; Weeke, B, 1988) |
| "The effects of oral treatment with terbutaline sustained-release (SR) tablets (Bricanyl Depot) were studied in nine patients who had bronchial asthma and marked diurnal variation in ventilatory function." | 5.06 | Terbutaline sustained-release tablets in nocturnal asthma--a placebo-controlled comparison between a high and a low evening dose. ( Anehus, S; Dahl, R; Harving, H; Säwedal, L, 1988) |
| " We have compared in 10 asthmatic patients the bronchodilator responses following inhalations of terbutaline sulphate from Nebuhaler after delays of 1, 5 and 30 seconds and following placebo inhalation." | 5.06 | Bronchodilatory therapy with nebuhaler: how important is the delay between firing the dose and inhaling? ( Clarke, SW; Morén, F; Newman, SP; Woodman, G, 1988) |
| "We have investigated the use of subcutaneous terbutaline in 17 patients with brittle asthma and five patients with chronic severe asthma." | 5.06 | Long term treatment of severe asthma with subcutaneous terbutaline. ( Ayres, JG; Cochrane, GM; O'Driscoll, BR; Ruffles, SP, 1988) |
| "To evaluate whether the potency of a long-acting selective beta 2-agonist negates the need for cromolyn, 27 children, aged 6 to 12 years, with mild to moderate asthma requiring long-term medication, were assessed for the therapeutic effects of cromolyn and/or terbutaline by jet nebulizer." | 5.06 | Double-blind evaluation of nebulized cromolyn, terbutaline, and the combination for childhood asthma. ( Bierman, CW; Furukawa, CT; Menendez, R; Pierson, WE; Shapiro, GG; Sharpe, MJ, 1988) |
| "The effect of terbutaline, in a slow-release preparation, on spirometry and arterial blood-gases, was studied in fourteen patients with nocturnal asthma." | 5.06 | Nocturnal asthma: effects of slow-release terbutaline on spirometry and arterial blood-gases. ( Eklundh, G; Eriksson, L; Jonson, B; Persson, G, 1988) |
| "The objective of this open randomized cross-over study was to compare the clinical efficacy and safety of a recently introduced beta-2 mimetic, tulobuterol, with fenoterol in asthma patients." | 5.06 | Open cross-over comparison of tulobuterol and fenoterol in asthmatic adult patients. ( Azanza, JR; Dal-Re, R; Rivero, A; Sanchez, J, 1988) |
| "Twelve adult asthmatic patients participated in an open, randomized, cross-over comparison between cumulatively increasing doses of terbutaline sulphate administered via the multiple dose powder inhaler (Turbuhaler) or via a pressurized inhaler." | 5.06 | A new multiple dose powder inhaler, (Turbuhaler), compared with a pressurized inhaler in a study of terbutaline in asthmatics. ( Gruvstad, E; Persson, G; Ståhl, E, 1988) |
| "We compared the bronchodilating effects of intravenously administered enprofylline (2 mg/kg) with nebulized terbutaline (10 mg) in patients presenting to hospital with acute asthma in a multicenter double-blind parallel study." | 5.06 | Comparison of the effects of nebulized terbutaline with intravenous enprofylline in patients with acute asthma. ( Bryant, D; Burdon, J; Marlin, G; Mitchell, C; O'Hehir, R; Ruffin, R; Webb, S; Wilson, J; Woolcock, A, 1988) |
| "Subcutaneous adrenaline and terbutaline have been compared in a double blind study of 20 patients with acute severe asthma presenting to an accident and emergency department." | 5.06 | Subcutaneous adrenaline versus terbutaline in the treatment of acute severe asthma. ( Clarke, SW; Millar, AB; Pavia, D; Spiteri, MA, 1988) |
| "Twenty-three patients with acute severe asthma were treated in a randomized double-blind way by either intravenous terbutaline two times at an hour interval 6 micrograms/kg or inhaled terbutaline two times 0." | 5.06 | Intravenous versus nebulized terbutaline in patients with acute severe asthma; a double-blind randomized study. ( Elinck, W; Lamont, H; Pauwels, R; Van der Straeten, M; Van Renterghem, D, 1987) |
| "In fifteen patients with asthma tulobuterol, a new beta 2-adrenoceptor agonist, given by inhalation in 100 micrograms increments up to a cumulative dose of 600 micrograms produced dose related increases in both the FEV1 and FVC." | 5.06 | Bronchodilator activity of a new inhaled beta 2-adrenoceptor agonist, tulobuterol and its protective effect in exercise-induced asthma. ( Patel, KR, 1986) |
| "Twelve patients with bronchial asthma participated in a blind, randomized, crossover study comparing the effects of 500 micrograms terbutaline in one inhalation, 125 micrograms in four inhalations taken in rapid succession, and 125 micrograms in four inhalations taken with an intervening time interval of 30 min." | 5.06 | Effects of divided doses of a bronchodilator aerosol and the intervening time interval on the forced expiration. ( Bake, B; Hidinger, KG, 1986) |
| "The efficacy and side effects of oral or inhaled terbutaline were examined in 13 mild-to-moderate asthmatic patients (ages 12 to 71 years) on maintenance theophylline (levels 10 to 25 micrograms/ml)." | 5.06 | Addition of terbutaline to optimal theophylline therapy. Double blind crossover study in asthmatic patients. ( Kray, KT; Nelson, HS; Vandewalker, ML; Weber, RW, 1986) |
| "The bronchodilator response to cumulative doses of terbutaline administered by metered dose inhaler with and without a conical spacer device and by Acorn nebuliser has been compared in groups of patients with chronic severe and moderately severe asthma." | 5.06 | Domiciliary comparison of terbutaline treatment by metered dose inhaler with and without conical spacer in severe and moderately severe chronic asthma. ( Gould, G; Kendrick, AH; Laszlo, G; O'Reilly, JF, 1986) |
| ", terbutaline) would reduce BR in children with asthma and with minimal or no bronchoconstriction." | 5.06 | Effect of long-term treatment with inhaled corticosteroids and beta-agonists on the bronchial responsiveness in children with asthma. ( Kerrebijn, KF; Neijens, HJ; van Essen-Zandvliet, EE, 1987) |
| "The study was designed to compare terbutaline inhaled via a 750 ml spacer (Nebuhaler) with subcutaneous adrenaline injection as a first-line treatment for acute severe asthma." | 5.06 | Terbutaline pressurised aerosol inhaled via a Nebuhaler--an effective alternative to subcutaneous adrenaline for treatment of acute severe asthma. ( Charoenratanakul, S; Youngchaiyud, P, 1987) |
| "4 years who needed regular use of antiasthmatic drugs and showed after abandoning them with the appropriate intervals a FEV1 below 85% of their highest previous value, received in a randomized, double-blind crossover fashion two puffs of terbutaline 1 hour apart on two consecutive days." | 5.06 | [Bronchodilating effect of terbutaline inhaled with and without a tube spacer in asthmatic children]. ( Bilbao Aburto, A; Gutiérrez Mazorriaga, P; Ubetagoyena Arrieta, M; Vázquez Cordero, C, 1987) |
| "Terbutaline sulphate was administered to 40 adult asthmatic patients via an ordinary metered-dose inhaler (MDI) or one connected to a 750-ml spacer in an open, randomized, crossover study." | 5.06 | Airflows after inhalation of terbutaline sulphate aerosol from a 750-ml spacer for four weeks. ( Eriksson, NE; Hagstad, H; Hidinger, KG; Löfgren, L; Perk, J; Rosenhall, L; Stiksa, G; Ström, K, 1986) |
| "In a double-blind, cross-over study, 21 children with acute severe asthma were treated with terbutaline (0." | 5.06 | Comparison of Nebuhaler and nebulizer treatment of acute severe asthma in children. ( Fuglsang, G; Pedersen, S, 1986) |
| "In a double-blind crossover study, 16 children with asthma were treated with two puffs of terbutaline (0." | 5.06 | The importance of a pause between the inhalation of two puffs of terbutaline from a pressurized aerosol with a tube spacer. ( Pedersen, S, 1986) |
| "The equipotent bronchodilating doses of terbutaline and a new beta-agonist KWD 2131 with a relatively stronger anti-allergic (inhibition of mediator release) than bronchodilating effect given in nebulized form was estimated in eight patients with intrinsic asthma." | 5.05 | New beta-agonist, KWD 2131, compared with terbutaline in asthmatics. A cumulative dose-response study. ( Hegardt, B; Löwhagen, O; Svedmyr, N, 1980) |
| "The reproducibility of the histamine challenge in seven asymptomatic patients with extrinsic asthma, provoked four times each with 1-2 weeks interval, was investigated." | 5.05 | Histamine-induced bronchospasm. Its reproducibility and usage in clinical evaluation of the sub-threshold bronchodilating dose of a new beta-agonist, KWD 2131. ( Hegardt, B; Löwhagen, O; Svedmyr, N, 1980) |
| "The selective anti-allergic effect of a new beta-agonist, KWD 2131, in inhibiting allergen-provoked asthma was compared with that of placebo in a double-blind crossover study." | 5.05 | Evaluation of the protective effect of a new beta-agonist, KWD 2131, on allergen-induced bronchospasm. ( Hegardt, B; Löwhagen, O; Svedmyr, N, 1980) |
| "The influence of pretreatment with equipment bronchodilating doses of intravenous theophyllamine and inhaled terbutaline on the effect of five terbutaline inhalations was investigated in a cross-over study in six adult asthmatics with stable and reproducible bronchoconstriction." | 5.05 | Does theophylline potentiate inhaled beta 2-agonists? ( Svedmyr, K; Svedmyr, N, 1982) |
| "5 mg) combined with 280 mg anhydrous theophylline orally in the randomized, double-blind, cross-over study in eight asthmatics." | 5.05 | Effects of oral theophylline combined with oral and inhaled beta-2-adrenostimulants in asthmatics. ( Svedmyr, K, 1982) |
| "In 8 asthmatic patients a comparative study was performed of the ventilatory and haemodynamic effects of the beta 1-receptor stimulator prenalterol and the beta 2-receptor stimulator terbutaline infused in increasing doses after a placebo." | 5.05 | Ventilatory and haemodynamic effects of prenalterol and terbutaline in asthmatic patients. ( Greefhorst, AP; van Herwaarden, CL, 1983) |
| "To study the cardioselectivity of xamoterol, eight asthmatic patients took part in a randomised, double-blind, cross-over study, in which xamoterol or saline were infused, followed by four increasing doses of terbutaline i." | 5.05 | Effects of xamoterol (ICI 118,587) in asthmatic patients. ( Löfdahl, CG; Svedmyr, N, 1984) |
| "In ten adult patients with severe, partially reversible airflow obstruction due to asthma, with or without co-existent chronic bronchitis, the acute bronchodilator responses of ipratropium bromide (40 micrograms) and terbutaline (500 micrograms) from metered-dose inhalers, atropine methonitrate (2 mg) as a wet aerosol and placebo were compared in a double blind trial." | 5.05 | Use of ipratropium bromide in patients with severe airways obstruction. ( Campbell, AH; Holmes, PW; Pierce, RJ, 1982) |
| "A study was performed to investigate changes in plasma cyclic adenosine monophosphate (cyclic AMP), peak expiratory flow and arterial blood gas tensions in response to running exercise and terbutaline sulphate aerosol in asthmatic patients regularly receiving sympathomimetic bronchodilator aerosols." | 5.05 | Plasma cyclic AMP levels in response to exercise and terbutaline sulphate aerosol in normal and asthmatic subjects. ( Anderson, SD; Bye, PT; Daviskas, E; Marty, JJ; Sampson, D, 1980) |
| "Eight asthmatic patients and two normal subjects performed two identical exercise tests 140 minutes apart (first test preceded by inhalation of saline and the second by terbutaline sulphate)." | 5.05 | Arterial plasma histamine levels at rest, and during and after exercise in patients with asthma: effects of terbutaline aerosol. ( Anderson, SD; Bye, PT; Ferris, L; Schoeffel, RE; Seale, JP; Taylor, KM, 1981) |
| "In eight asthmatic and six normal subjects serum terbutaline concentrations were correlated with changes in FEV1, MEF50%, Gaw, sGaw, and plasma cAMP concentrations after administration of 0." | 5.05 | Terbutaline serum concentrations related to different lung function parameters and beta-receptor function. ( Bruynzeel, PL; Kreukniet, J; Leferink, JG; Maes, RA; Serra, R; Tabingh Suermondt, W; van den Berg, W, 1983) |
| "The acute bronchomotor effect of nabilone, a synthetic cannabinoid compound, was compared to that of terbutaline sulfate and placebo in six healthy and six asthmatic subjects." | 5.05 | Comparison of bronchial effects of nabilone and terbutaline in healthy and asthmatic subjects. ( Calvarese, B; Gong, H; Tashkin, DP, 1983) |
| "In 8 asthmatic subjects, serum concentrations of terbutaline were correlated with changes in volume of air expelled in the first second of forced expiration (FEV1), other parameters of lung function, c-AMP plasma concentrations and finger tremor values after administration of either 5 mg terbutaline sulphate orally, 0." | 5.05 | The effects of oral and subcutaneous administration of terbutaline in asthmatic patients. ( Bruynzeel, PL; Fokkens, JK; Kreukniet, J; Leferink, JG; Maes, RA; van den Berg, W, 1984) |
| "The protective effects of oxyphenonium bromide, terbutaline and theophylline were compared in 8 asthmatic patients by determination of the degree of non-specific airway reactivity after 1 week of oral treatment according to a fixed dose scheme in a double-blind random order: oxyphenonium bromide 3 X 10 mg; terbutaline 3 X 5 mg; theophylline 2 X 300 mg and placebo." | 5.05 | Protective effect of oral oxyphenonium bromide, terbutaline and theophylline against the bronchial obstructive effects of inhaled histamine, acetylcholine and propranolol. ( de Vries, K; de Zeeuw, RA; Greving, J; Jonkman, JH; Koëter, GH; Leferink, J; Meurs, H; Sluiter, HJ, 1984) |
| "A study to compare the bronchodilator effect of salbutamol powder (Ventolin, 200 micrograms) administered via a Rotahaler (SR), with that of terbutaline sulphate (Bricanyl, 500 micrograms) administered via a Misthaler (TM) was carried out in 25 children with stable moderate to severe asthma." | 5.05 | Bronchodilator effects of salbutamol powder administered via Rotahaler and of terbutaline aerosol administered via Misthaler. A comparison study in children with asthma. ( Mellis, CM; Sharota, E; Simpson, SJ; Towns, SJ, 1983) |
| "In 11 asthmatic subjects the relative magnitude and the site of airway bronchoconstriction were compared after the oral administration of 40 mg of propranolol and 2." | 5.05 | Beta-blockers in bronchial asthma: effect of propranolol and pindolol on large and small airways. ( Argiropoulou, V; Louridas, G; Patakas, D; Tsara, V, 1983) |
| "A double-blind randomized study of 50 patients was conducted to evaluate the efficacy and safety of terbutaline sulfate aerosol and isoproterenol sulfate aerosol in the treatment of patients with moderate to severe asthma." | 5.05 | Terbutaline sulfate and isoproterenol sulfate (metered dose aerosols) in the treatment of asthma. ( Kemp, JP; Meltzer, EO; Orgel, HA; Welch, MJ, 1983) |
| "The influence on lung function of small cumulative doses (31 + 31 + 63 + 125 + 250 micrograms) of terbutaline inhalations from a pressurized aerosol with a 750 ml spacer was evaluated in 12 stable asthmatics." | 5.05 | Bronchodilation of terbutaline in small doses from a 750 ml spacer. A cumulative dose-response study. ( Hidinger, KG; Munch, EP; Weeke, B, 1983) |
| "The efficacy of terbutaline inhaled from different aerosol systems was studied in 13 adult asthmatics." | 5.05 | Comparative efficacy of different methods of nebulising terbutaline. ( Bundgaard, A; Pedersen, JZ, 1983) |
| "Seven asthmatic patients were studied in a single-blind randomized, crossover study after oral administration of 20 mg nifedipine or placebo." | 5.05 | Nifedipine--a calcium channel blocker--in asthmatic patients. Interaction with terbutaline. ( Löfdahl, CG; Svedmyr, K; Svedmyr, N, 1984) |
| "25 mg terbutaline sulfate on serum potassium (K+), sodium (Na+), glucose, and insulin in a group of asymptomatic asthmatics." | 5.05 | The effect of subcutaneously administered terbutaline on serum potassium in asymptomatic adult asthmatics. ( Burki, NK; Küng, M; White, JR, 1984) |
| "A bronchodilator aerosol, terbutaline sulphate, was administered to 18 asthmatic children, mean age 8." | 5.05 | Childhood asthma: improved efficacy of pressurized terbutaline aerosol by use of a 750-ml spacer. ( Hidinger, KG; Kjellman, NI, 1984) |
| "We compared the effect of inhaled terbutaline sulphate (1,000 micrograms), cromolyn sodium (20 mg), terbutaline plus cromolyn, and placebo on the response to respiratory heat loss (RHL) in 10 asthmatics in whom terbutaline alone did not completely inhibit the response to RHL." | 5.05 | Bronchoconstriction stimulated by airway cooling. Better protection with combined inhalation of terbutaline sulphate and cromolyn sodium than with either alone. ( Hargreave, FE; Latimer, KM; Morris, MM; O'Byrne, PM; Roberts, R, 1983) |
| "In a pilot study two patients with brittle asthma and two with morning dipping received terbutaline or a placebo administered subcutaneously either by continuous infusion or in injections every six hours." | 5.05 | Subcutaneous terbutaline and control of brittle asthma or appreciable morning dipping. ( Ayres, J; Cochrane, GM; Fish, DR; Skinner, C; Wheeler, DC; Wiggins, J, 1984) |
| "Patients with acute asthmatic attacks were prospectively randomized to receive either aerosolized terbutaline or subcutaneous epinephrine." | 5.05 | A comparative study of aerosolized terbutaline and subcutaneously administered epinephrine in the treatment of acute bronchial asthma. ( Baughman, RP; James, W; Ploysongsang, Y, 1984) |
| "The bronchodilator effect of 400 micrograms of salbutamol powder (2 capsules) administered by a rota-haler was compared with that of 500 micrograms of terbutaline (2 metered doses) administered as an aerosol via a tube-spacer in a group of ten stable asthmatic children (mean age 12 years)." | 5.05 | Comparison of salbutamol powder with terbutaline aerosol administered with a tube spacer in asthmatic children. ( Francis, PW; Kelly, CA; Zimmerman, PV, 1983) |
| "Eight asthmatic patients were investigated in a double-blind cross-over study after oral administration of 100 mg atenolol, 10 mg metoprolol and placebo." | 5.05 | Cardioselectivity of atenolol and metoprolol. A study in asthmatic patients. ( Löfdahl, CG; Svedmyr, N, 1981) |
| "A double-blind, placebo-controlled study of the haemodynamic and ventilatory effects of two beta 1-selective adrenoceptor blockers and their interaction with the beta 2-adrenoceptor agonist terbutaline was carried out in eight asthmatic patients." | 5.05 | Ventilatory and haemodynamic effects of terbutaline infusion during beta 1-selective blockade with metoprolol and acebutolol in asthmatic patients. ( Greefhorst, AP; van Herwaarden, CL, 1982) |
| "Increasing doses of fenoterol and terbutaline were administered by inhaler to 12 stable asthmatics in a double-blind crossover trial." | 5.05 | A comparative double-blind study of the bronchodilator effects and side effects of inhaled fenoterol and terbutaline administered in equipotent doses. ( Costello, JF; Frame, MH; Gray, BJ, 1982) |
| "Double-blind cross-over studies of oral and inhaled terbutaline and salbutamol have been performed in two groups of asthmatic patients." | 5.05 | A comparison of the effects of different methods of administration of beta-2-sympathomimetics in patients with asthma. ( Clark, TJ; Rees, J; Webb, J, 1982) |
| "Ten asthmatic patients inhaled terbutaline sulphate (250, 500, or 1000 micrograms) or placebo on separate days, double blind and in random order, 30 minutes before isocapnic hyperventilation induced by cold air inhaled in doses that increased in a precisely controlled manner." | 5.05 | Inhibition of the bronchial response to respiratory heat exchange by increasing doses of terbutaline sulphate. ( Hargreave, FE; Morris, M; O'Byrne, PM; Roberts, R, 1982) |
| "The effect of adding theophylline to treatment with a beta2-adrenoceptor stimulant was studied in 18 asthmatic children in a double-blind cross-over trial." | 5.05 | Combined treatment with sustained-release theophylline and beta2-adrenoceptor-stimulating agents in chronic childhood asthma. ( Foucard, T; Lindström, B; Lönnerholm, G, 1981) |
| "The peak response and the duration of bronchodilator effect were measured after four inhalations at 20 min intervals of 250 micrograms of aerosolized terbutaline in 13 patients with bronchial asthma." | 5.05 | Aerosolized terbutaline in asthmatics: development of subsensitivity with long-term administration. ( Nelson, HS; Smith, JA; Weber, RW, 1982) |
| "Ventilatory function and whole lung mucociliary clearance have been assessed in 10 patients with mild stable asthma following inhalation of 1 mg of the beta-adrenergic receptor agonist terbutaline sulphate (Bricanyl, Astra Pharmaceuticals) from a metered dose inhaler (MDI)." | 5.05 | Effects of terbutaline sulphate aerosol on bronchodilator response and lung mucociliary clearance in patients with mild stable asthma. ( Bateman, JR; Clarke, SW; Newman, SP; Pavia, D; Sheahan, NF, 1983) |
| "The bronchodilator response to aerosolized terbutaline and optimal doses of theophylline, given singly and in combination, was studied in ten patients with perennial asthma." | 5.05 | Theophylline and aerosolized terbutaline in the treatment of bronchial asthma. Double-blind comparison of optimal doses. ( Nelson, HS; Smith, JA; Weber, RW, 1980) |
| "The purpose of this study was to compare the efficacy of a new bronchodilator, reproterol with standard bronchodilators terbutaline and theophylline in patients with allergic asthma." | 5.05 | Inhibition of antigen-induced bronchoconstriction with reproterol, a new beta agonist-xanthine derivative. ( Klaustermeyer, WB; Kuhn, GJ; Santiago, SM; Weliky, I, 1981) |
| "In a double-blind crossover controlled study, intravenous (IV) or nebulized terbutaline was given to eight patients with moderately severe asthma on two separate days." | 5.05 | Comparison of intravenous and inhaled terbutaline in the treatment of asthma. ( Clark, TJ; Denison, DM; Payne, CR; Pierce, RJ; Williams, SJ, 1981) |
| ": reproterol (Bronchospasmin), terbutalin (Bricanyl) and fenoterol (Berotec) were examined in a randomized study in 90 patients." | 5.05 | [Postoperative respiratory therapy: bronchospasmolytic activity and side-effects of some recently introduced beta-sympatheticomimetic agents (author's transl)]. ( Beer, S; Brandl, M; Hamer, P, 1981) |
| "In patients with acute severe asthma, 5 mg of terbutaline by inhalation and 500 microgram intravenously in divided doses both produced equally effective but not maximal bronchodilatation." | 5.05 | Comparison of inhaled and intravenous terbutaline in acute severe asthma. ( Clark, TJ; Williams, SJ; Winner, SJ, 1981) |
| "Terbutaline sulphate (Bricanyl; Keatings) aerosol or placebo aerosol was administered in a randomized fashion to 26 asthmatic children with proven exercise-induced asthma." | 5.05 | The effect of terbutaline sulphate on exercise-induced asthma in children. ( Weinberg, EG, 1982) |
| "The effect of inhaled or oral terbutaline on the subsequent response to inhaled terbutaline was studied using a double-blind cross-over technique in 12 asthmatic patients." | 5.05 | Do oral and inhaled terbutaline have different effects on the lung? ( Clark, TJ; Hetzel, MR; Shaw, RJ; Waller, JF, 1982) |
| "0 mg of terbutaline or placebo disclosed that terbutaline produced a highly significant protective effect against exercise-induced asthma." | 5.05 | Effect of oral terbutaline on exercise-induced asthma. ( O'Brien, SR; Sly, RM, 1982) |
| "The bioavailability of three different theophylline tablets (microcrystallinic theophylline, Theolair, Nuelin, 3M Riker), choline theophyllinate as a new film-coated tablet (Teovent, Ferrosan, Sweden) and theophyllaminopropanol (Oxyphylline, Draco, Sweden) was investigated in eight adult asthmatics and a randomized, double-blind, cross-over study." | 5.05 | Bioavailability of theophylline from three different tablets in asthmatic patients and their bronchodilating effects in combination with terbutaline inhalation. ( Mellstrand, T; Svedmyr, K; Svedmyr, N, 1982) |
| "The effect of the beta 1-selective adrenoceptor blocker, metoprolol, on ventilatory function was studied in eight asthmatic patients in relation to the plasma level of the agent following its administration in ordinary and slow-release tablets." | 5.05 | Ventilatory effects of ordinary and slow-release tablets of metoprolol in asthmatic patients. ( van den Bergh, JH; van Herwaarden, CL, 1981) |
| "The effects of fenoterol and terbutaline, new beta 2 selective bronchodilators each administered orally in five mgm doses, was assessed in 33 asthmatics treated for six weeks." | 5.05 | A comparison of oral terbutaline and fenoterol in asthma. ( Miller, WC; Rice, DL, 1980) |
| "Bronchodilation and side effects of 28 days treatment with either a full therapeutic dose of theophylline slow-release preparation 500 mg twice daily (400-600 mg), a slow-release terbutaline preparation 10 mg twice daily or combinations of the 2 drugs in full or half doses were evaluated in 31 asthmatic outpatients in a double-blind, randomized crossover design." | 5.05 | Long-term oral therapy of asthma with terbutaline and theophylline, alone and combined. ( Gnosspelius, Y; Gymose, E; Laursen, LC; Taudorf, E; Weeke, B, 1985) |
| "Procaterol, a new beta-2 adrenoceptor stimulant, was studied in a double-blind, placebo-controlled, cross-over trial in patients with bronchial asthma." | 5.05 | Procaterol and terbutaline in bronchial asthma. A double-blind, placebo-controlled, cross-over study. ( Dahl, R; Harving, H; Henriksen, J; Rønne, K; Schøler, P, 1985) |
| "The efficacy of terbutaline (1 mg) administered from pressurised aerosol through a nebuhaler was compared in a crossover trial with terbutaline (4 mg) as nebulised solution in 20 patients with acute severe asthma." | 5.05 | Pear shaped spacer nebuhaler compared with nebulised solution for terbutaline administration in acute severe asthma. ( Beasley, CR; O'Donnell, TV, 1985) |
| "Thirty children 8-13 years old, with perennial asthma and with a reversibility of greater than or equal to 20% in lung function (FEV1) were given a sustained-release preparation of terbutaline sulphate 5 mg twice a day and ordinary tablets 2." | 5.05 | Terbutaline depot tablets in childhood asthma. A double-blind controlled study. ( Foged, N; Høst, A; Ljungholm, K, 1985) |
| "Twenty-seven asthmatic outpatients were randomly treated with bambuterol 30 mg administered once daily before going to bed and sustained release terbutaline 10 mg twice daily in a 14 day, double blind cross over study." | 5.05 | Bambuterol: effects of a new anti-asthmatic drug. ( Faurschou, P; Gnosspelius, Y; Laursen, LC; Pedersen, BK; Weeke, B, 1985) |
| "The acute cardiopulmonary effects of oral albuterol, 4 mg, metaproterenol sulfate, 20 mg, and terbutaline sulfate, 5 mg, were compared over eight hours in 20 moderate to severe asthmatics." | 5.05 | Comparison of the acute cardiopulmonary effects of oral albuterol, metaproterenol, and terbutaline in asthmatics. ( Biedermann, AA; Chu, TJ; Wolfe, JD; Yamate, M, 1985) |
| "We studied the effect of oral terbutaline on serum theophylline levels in 12 children with asthma." | 5.05 | Reduction of serum theophylline levels by terbutaline in children with asthma. ( Danziger, Y; Garty, M; Ilfeld, D; Rosenfeld, JB; Varsano, I; Volwitz, B, 1985) |
| "In a double blind cross-over study the bronchodilator response after eight different modes of inhalation of terbutaline from a pressurized aerosol with a tube spacer was assessed in fifteen asthmatic children." | 5.05 | Optimal use of tube spacer aerosols in asthmatic children. ( Pedersen, S, 1985) |
| "We performed a double-blind crossover study to compare the effects of long-term treatment of inhaled budesonide and terbutaline on bronchial hyperreactivity in 17 patients with allergic asthma." | 5.05 | Changes in bronchial hyperreactivity induced by 4 weeks of treatment with antiasthmatic drugs in patients with allergic asthma: a comparison between budesonide and terbutaline. ( de Vries, K; Koëter, GH; Kraan, J; Sluiter, HJ; vd Mark, TW, 1985) |
| "In a single-blind, crossover study 10 adult asthmatic patients received a theophylline-ephedrine combination tablet (theophylline 90 mg, ephedrine 16 mg and phenobarbital 25 mg in an immediate release layer and theophylline 90 mg and ephedrine 32 mg in a sustained release layer) twice daily or terbutaline 5 mg three times daily for two weeks." | 5.04 | A comparison of a theophylline-ephedrine combination with terbutaline. ( Alcala, JC; Bush, RK; Lee, TP; Smith, AM; Welling, PG, 1978) |
| "Terbutaline, a new bronchodilator drug reported to have selective affinity for beta 2-adrenergic receptors, was compared with epinephrine in the treatment of 49 adult subjects with acute bronchial asthma." | 5.04 | A comparative study of subcutaneously administered terbutaline and epinephrine in the treatment of acute bronchial asthma. ( Henis, MM; Heurich, AE; Leffler, CT; Lyons, HA; Smith, PR, 1977) |
| "Comparison of the bronchodilator and cardiovascular effects of subcutaneous terbutaline and epinephrine in the treatment of acute asthmatic attacks in children disclosed that bronchodilation occurred with 5 min after subcutaneous injection of either drug (0." | 5.04 | Comparison of subcutaneous terbutaline with epinephrine in the treatment of asthma in children. ( Badiei, B; Faciane, J; Sly, RM, 1977) |
| "Twenty-one patients with asthma were studied in a double-blind manner for the effects of three aerosolized bronchodilators (isoproterenol, metaproterenol and terbutaline) on small, large and mixed airways, blood pressure, heart rate and various blood chemistries." | 5.04 | A comparative study of the aerosolized bronchodilators, isoproterenol, metaproterenol and terbutaline in asthma. ( Novey, HS; Roth, MJ; Wilson, AF, 1977) |
| "Ninety-nine patients with severe bronchial asthma were tested with two inhalations of Terbutaline." | 5.04 | Terbutaline: an effective bronchodilator by inhalation. ( Goldgraber, MB, 1977) |
| "The bronchodilator effects of terbutaline, 500 microng, and salbutamol, 200 microng, by pressurised aerosol were compared in 16 patients (eight asthma, eight chronic bronchitis with asthma)." | 5.04 | Comparison of terbutaline and salbutamol aerosols. ( Hartnett, BJ; Marlin, GE, 1977) |
| "The effects of terbutaline, ephedrine, and placebo on the cardiovascular and pulmonary systems have been compared in 24 asthmatic children." | 5.04 | Terbutaline and ephedrine in asthmatic children. ( Avner, SE; Blumberg, BS; Blumberg, MZ; Ginchansky, EJ; Taylor, JC; Tinkelman, DG, 1977) |
| "The effect of administration of terbutaline on the pulmonary and cardiovascular systems was studied in ten children with status asthmaticus." | 5.04 | Terbutaline in the treatment of status asthmaticus. ( Davis, WJ; Mellins, RB; Pang, LM; Rodriguez-Martinez, F, 1977) |
| "We have compared bronchodilator responses to atropine and terbutaline in 39 chronic bronchitics and 16 stable asthmatics." | 5.04 | Comparative bronchodilator responses to atropine and terbutaline in asthma and chronic bronchitis. ( Chick, TW; Jenne, JW, 1977) |
| "In 17 patients with moderate to severe asthma, we compared acute bronchodilator effects of the following drugs or drug combinations using a double-blind crossover design: terbutaline, 5; aminophyline 400; terbutaline, 5, plus aminophyline, 400; terbutaline, 2." | 5.04 | Bronchodilator effects of terbutaline and aminophylline alone and in combination in asthmatic patients. ( Calvarese, B; Simmons, M; Tashkin, DP; Wolfe, JD, 1978) |
| "In a double-blind trial of six weeks' duration 30 chronic asthmatic outpatients were treated with 5 mg tablets of either fenoterol or terbutaline two to four times daily." | 5.04 | A comparative evaluation of fenoterol and terbutaline in the treatment of asthma. ( Chervinsky, P, 1978) |
| "Fenoterol and terbutaline, two long-acting beta 2-adrenoceptor agonists in aerosol form, were compared in an 8-wk randomized double-blind crossover study in 22 mild to moderately severe asthmatics." | 5.04 | Comparison of four weeks' treatment with fenoterol and terbutaline aerosols in adult asthmatics. A double-blind crossover study. ( Anderson, M; Dimmock, S; Green, M; Greenacre, JK; Mansfield, L; Trembath, PW; Wadsworth, J, 1979) |
| "In a single-blind, placebo-controlled, cross-over study, the effects of intravenous 20 micrograms NAB 365 (clenbuterol) and intravenous 250 microgram terbutaline were compared in nine asthmatic patients with bronchospasm induced by exercise." | 5.04 | Intravenous NAB 365 (clenbuterol) and terbutaline in exercise-induced bronchospasm (EIB). ( Del Bono, N; Quartieri, F; Vibelli, C, 1979) |
| "In a double-blind, single-dose trial asthmatic children, ages two to six years, received 25, 50 or 100 ug/kg terbutaline and placebo on four consecutive days." | 5.04 | Terbutaline elixir in preschool children with chronic asthma. ( Archer, JW; Pagtakhan, RD; Pizey, DM; Simons, FE, 1979) |
| "The acute bronchodilator effect of the beta 2-adrenoceptor agonist terbutaline was tested single-blind cross-over in out-patients with chronic obstructive airways disease (intrinsic asthma)." | 5.04 | [Lung function studies with the bronchodilator terbutaline]. ( Bonelli, J; Hitzenberger, G; Kaik, G; Laggner, A; Magometschnigg, D, 1979) |
| "A double-blind crossover trial was conducted in 10 asthmatic patients for comparison of fenoterol with salbutamol, in 12 other asthmatic patients for comparison of reproterol with salbutamol, and in 15 other asthmatic patients for comparison of terbutaline with salbutamol." | 5.04 | [The bronchospasmolytics salbutamol, fenoterol, terbutaline and reproterol. Their effects and side effects in asthmatics after inhalation with an electric nebulizer]. ( Budmiger, H; Kyd, K; Scherrer, M, 1978) |
| "Measurements of peak expiratory flow rate during serial exercise tests were used to assess the efficacy of the beta adrenergic stimulants oral terbutaline (5 mg) and fenoterol aerosol (400 micrograms), in preventing post-exercise bronchoconstriction in 18 asthmatic subjects." | 5.04 | Inhaled and oral bronchodilator therapy in exercise induced asthma. ( Anderson, SD; Dolton, R; Lindsay, DA; Rozea, PJ, 1975) |
| "Because of reports of drug tolerance occurring with chronic use of adrenergic agents in asthma, we investigated cardiopulmonary responsiveness to ephedrine and to the beta-2 agent, tebutaline, following chronic drug administration for periods up to one year." | 5.04 | Cardiopulmonary effects of long-term bronchodilator administration. ( Cloninger, P; Davis, J; Novey, HS; White, D; Wilson, AF, 1976) |
| "Acute effects of oral terbutaline (5 mg), ephedrine (25 mg) and placebo on bronchial dynamics, heart rate, systolic and diastolic pressure and arterial blood gases at rest were compared over a period of 7 hours in 20 subjects with bronchial asthma using a double-blind crossover technique." | 5.04 | Double-blind comparison of acute bronchial and cardiovascular effects of oral terbutaline and ephedrine. ( Lee, YE; Meth, R; Simmons, DH; Tashkin, DP, 1975) |
| "Double-blind studies of the bronchodilator effects of rimiterol, terbutaline and a combination of rimiterol and terbutaline were performed in patients with chronic asthma." | 5.04 | Objective and subjective comparisons of terbutaline and rimiterol bronchodilator aerosols. ( Crompton, GK; Grant, IW; Paterson, IC; Shotter, V; Willey, RF, 1975) |
| "The bronchodilating effect, circulatory effects, and subjective side effects of ibuterol hydrochloride, the di-isobutyric acid ester of terbutaline, at two dose levels (2 and 4 mg) were compared with those of 5 mg terbutaline sulphate in a double-blind cross-over study on 12 patients with asthma." | 5.04 | Comparison between ibuterol hydrochloride and terbutaline in asthma. ( Arner, B; Magnusson, PO, 1976) |
| "A double blind study of 5 asthmatic subjects in remission demonstrated that the severity of bronchoconstriction after exercise was decreased by a single oral dose of 5 mg of terbutaline." | 5.04 | The effect of terbutaline in exercise-induced asthma. ( Anderson, GD; Jones, NL; Morse, JL, 1976) |
| " Bogie 2007 investigated the addition of intravenous terbutaline to high dose nebulised albuterol in children with acute severe asthma, requiring intensive care unit (ICU) admission." | 4.88 | Addition of intravenous beta(2)-agonists to inhaled beta(2)-agonists for acute asthma. ( Camargo, CA; Jones, AP; Milan, SJ; Rowe, BH; Travers, AH, 2012) |
| "Bambuterol, a biscarbamate ester prodrug of the beta 2 adrenergic agonist terbutaline, has been approved for the treatment of asthma in 28 countries." | 4.79 | Clinical pharmacokinetics of bambuterol. ( Sitar, DS, 1996) |
| "The acute bronchodilator effect of the beta 2-adrenoceptor agonist terbutaline was tested single-blind cross-over in out-patients with chronic obstructive airways disease (intrinsic asthma)." | 4.76 | [Pulmonary function tests with the bronchodilator Terbutaline]. ( Bonelli, J; Hitzenberger, G; Kaik, G; Laggner, A; Magometschnigg, D, 1979) |
| "Terbutaline administration given to pediatric patients experiencing a severe asthma exacerbation was not associated with decreased PICU or general hospital floor admission." | 4.12 | The Impact of Terbutaline as Adjuvant Therapy in the Treatment of Severe Asthma in the Pediatric Emergency Department. ( Adair, E; Dibaba, D; Fowke, JH; Snider, M, 2022) |
| "The present work aimed to improve the bioavailability of terbutaline sulphate (TS) and to prolong its nasal residence time for the treatment of asthma." | 3.96 | Novel lipid-polymer hybrid nanoparticles incorporated in thermosensitive in situ gel for intranasal delivery of terbutaline sulphate. ( Mohamed, S; Nasr, M; Refai, H; Salama, A, 2020) |
| " Effectiveness of switch was assessed as the proportion without severe asthma exacerbation and the proportion achieving risk domain asthma control (RDAC; no asthma-related hospitalization, antibiotics without upper respiratory diagnosis or acute course of oral corticosteroids) and overall asthma control (OAC; RDAC and ≤ 200 μg salbutamol/≤500 μg terbutaline average daily dose) comparing 1 year after and before the switch." | 3.91 | Real-life effectiveness of inhaler device switch from dry powder inhalers to pressurized metred-dose inhalers in patients with asthma treated with ICS/LABA. ( Ban, GY; Carter, V; Hardjojo, A; Jie, JLZ; Lee, HY; Park, HS; Price, DB; Van Boven, JFM; Wan Yau Ming, S; Yoon, D, 2019) |
| "Terbutaline aerosol and budesonide suspension are commonly used in the treatment of bronchial asthma, and budesonide suspension has local high efficiency and anti-inflammatory effects." | 3.88 | Effect of terbutaline combined with budesonide in treatment of bronchial asthma and rehabilitation nursing. ( Lu, W; Ruihong, Z; Xiaoli, L, 2018) |
| "The use of continuous intravenous terbutaline treatment in severe asthma attacks has been hampered by the lack of well-powered clinical trials where effects of such treatment are described in detail." | 3.88 | Safety of Terbutaline for Treatment of Acute Severe Pediatric Asthma. ( Doymaz, S; Schneider, J, 2018) |
| "To investigate the influence of early initiation of IV terbutaline on the incidence of acute respiratory failure requiring mechanical ventilation in severe pediatric asthma." | 3.80 | Early administration of terbutaline in severe pediatric asthma may reduce incidence of acute respiratory failure. ( Doymaz, S; Sagy, M; Schneider, J, 2014) |
| "Long-term subcutaneous or intravenous infusion of terbutaline has been used to stabilize asthma in patients enduring frequent hospital admissions due to severe asthma despite maximum therapy." | 3.80 | Continuous terbutaline infusion in severe asthma in adults: a retrospective study of long-term efficacy and safety. ( Afridi, L; Ayres, JG; Mansur, AH; Sullivan, J; Wilson, D, 2014) |
| "Aggravation of asthmatic response (asthmatic attack, 2 cases) and adverse events (tremor, 1 case) due to a switch from a brand-name tulobuterol tape to a generic tape were recently reported." | 3.78 | [Questionnaire survey on the change of asthmatic response, adverse events and product usability due to drug switching between name-brand and generic tulobuterol tapes]. ( Hori, S; Izumi, T; Miki, A; Satoh, H; Sawada, Y, 2012) |
| "These findings suggest that polymorphisms of β(2)-AR 16 are related to nocturnal asthma and polymorphisms of β(2)-AR 27 are associated with the variable responses to the inhaled terbutaline in children with nocturnal and nonnocturnal asthma." | 3.77 | Polymorphisms of the β2-adrenergic receptor correlated to nocturnal asthma and the response of terbutaline nebulizer. ( Chen, SJ; Cheng, SN; Fan, HC; Huang, HL; Lee, MY; Wang, CC, 2011) |
| "Tulobuterol patches are long-acting bronchodilators for percutaneous absorption including the β(2)-adrenoreceptor agonist tulobuterol, as a main ingredient, used for long-term management of pediatric asthma." | 3.76 | Comparative study of skin permeation profiles between brand and generic tulobuterol patches. ( Abe, T; Arisaka, O; Fukuda, H; Yoshihara, S, 2010) |
| "The study was undertaken to investigate the influence of once-daily treatment with montelukast (Singulair; MSD; Glattbrugg, Switzerland) on levels of exhaled nitric oxide (eNO) and lung function in preschool children with asthma." | 3.73 | The effect of montelukast on exhaled nitric oxide and lung function in asthmatic children 2 to 5 years old. ( Hamacher, J; Minocchieri, S; Moeller, A; Straub, DA; Wildhaber, JH, 2005) |
| "A 3-year old boy was treated for asthma by budesonide (Pulmicort) and terbutaline (Bricanyl) aerosols with an inhalation chamber (Babyhaler)." | 3.73 | [Connubial contact dermatitis to an inhaled corticosteroid]. ( Co Minh, HB; Guilhou, JJ; Guillot, B; Raison-Peyron, N; Vidal-Mazuy, A, 2005) |
| "We investigated the efficacy of nighttime transdermal tulobuterol (beta2-adrenoceptor agonist) chronotherapy for nocturnal asthma by assessing changes both in the frequency of symptoms and features of the circadian rhythm in peak expiratory flow (PEF), a measure of airway caliber." | 3.73 | Alteration of the circadian rhythm in peak expiratory flow of nocturnal asthma following nighttime transdermal beta2-adrenoceptor agonist tulobuterol chronotherapy. ( Burioka, N; Endo, M; Fukuoka, Y; Igawa, K; Miyata, M; Nakazaki, H; Shimizu, E; Suyama, H, 2005) |
| "(1) To determine the effect of intravenous terbutaline in children with acute severe asthma on parameters like heart rate, blood pressure, electrocardiogram and serum electrolytes; (2) to assess the safety profile and to evaluate the outcome of children treated with intravenous terbutaline for acute severe asthma." | 3.73 | Safety of intravenous terbutaline in acute severe asthma: a retrospective study. ( Kambalapalli, M; Nichani, S; Upadhyayula, S, 2005) |
| " This paper presents age- and gender-specific asthma death rates in patients prescribed the long-acting beta2-agonists salmeterol and bambuterol." | 3.71 | Age- and gender-specific asthma death rates in patients taking long-acting beta2-agonists: prescription event monitoring pharmacosurveillance studies. ( Martin, RM; Shakir, S, 2001) |
| "A continuous subcutaneous infusion of terbutaline (CSIT) was used to treat 8 children with chronic severe asthma who continued to experience frequent symptoms, despite treatment with regular oral prednisolone." | 3.71 | Subcutaneous terbutaline in children with chronic severe asthma. ( Balfour-Lynn, IM; Biggart, EA; Bush, A; Payne, DN; Rosenthal, M, 2002) |
| " To clarify part of the bronchodilating effects of theophylline, lymphocyte cyclic AMP (cAMP) and phosphodiesterase (PDE) activity in asthmatic patients and healthy adults were measured." | 3.70 | Effects of theophylline on lymphocyte phosphodiesterase activity. ( Fukuoka, M; Kubo, H; Nakahara, H; Nakajima, S; Ohkawa, K; Tohda, Y, 1998) |
| "Patients with asthma showed changes in the spectral acoustic analysis frequencies after the administration of a bronchodilator drug (terbutaline) during forced expiratory maneuvers." | 3.70 | Analysis of tracheal sounds during forced exhalation in asthma patients and normal subjects: bronchodilator response effect. ( Caminal, P; Fiz, JA; Izquierdo, J; Jané, R; Lores, L; Morera, J; Salvatella, D, 1999) |
| "To examine the cardiac toxicity as measured by elevations in serum cardiac troponin T (cTnT) and to compare creatine kinase (CK) and creatine kinase MB (CK-MB) and findings on electrocardiography (ECG) as markers of cardiac toxicity with cTnT during the infusion of intravenous terbutaline for the treatment of severe asthma in children." | 3.70 | Cardiac toxicity of intravenous terbutaline for the treatment of severe asthma in children: a prospective assessment. ( Adams, MJ; Burns, JP; Chiang, VW; Lipshultz, SE; Rifai, N; Weiner, DL, 2000) |
| "We report the pharmacokinetics and pharmacodynamics of tulobuterol patch, HN-078, in the treatment of childhood asthma." | 3.69 | Pharmacokinetics and pharmacodynamics of the tulobuterol patch, HN-078, in childhood asthma. ( Akimoto, K; Ebisawa, M; Iikura, Y; Ishizu, H; Kabayama, H; Miura, K; Sakaguchi, N; Tsubaki, T; Uchiyama, H; Yagi, K, 1995) |
| "Thirty five young subjects with long standing bronchial asthma were studied for the effects of terbutaline misthaler (500 micrograms) during acute asthma." | 3.69 | Effect of inhaled terbutaline on platelet activity in bronchial asthma. ( Chari, VI; Khatri, DP; Nabar, ST; Nadkar, MY; Paidhungat, AJ; Prabhu, SR; Salgaonkar, DS, 1994) |
| "A 40-yr-old woman with severe chronic asthma complained that her regular nebulized albuterol was exacerbating her symptoms." | 3.68 | Paradoxical bronchoconstriction with nebulized albuterol but not with terbutaline. ( Finnerty, JP; Howarth, PH, 1993) |
| "35 asthmatic patients, aged from 23 to 73 years, participated in an open study aimed to compare the efficacy and tolerance of terbutaline and budesonide administered in similar amounts with a metered-dose inhaler fitted with a spacer (Nebuhaler) or by a powder inhaler (Turbuhaler)." | 3.68 | [Efficacy and tolerance of terbutaline and budesonide administered via a pressurized aerosol inhaler or a Turbohaler in asthmatic patients]. ( Anderhub, HP; Langloh, P; Zellweger, JP, 1993) |
| "The purpose of this study was to investigate the effect of a constant infusion rate of terbutaline on circadian bronchial peak expiratory flow rate (PEFR), heart rate and arterial pressure in patients with asthma exacerbation." | 3.68 | Effects of a constant dose rate of terbutaline on circadian peak expiratory flow, heart rate and systolic arterial pressure in patients with asthma exacerbation. ( Arnaud, A; Bruguerolle, B; Lagier, F; Leonardelli, M; Orlando, JP; Philip-Joet, F; Pierson, F; Reynaud, M; Vervloet, D, 1992) |
| "An integrated pharmacokinetic-pharmacodynamic model was used to quantify the beta 2-blocking activity of metoprolol in seven asthmatic patients." | 3.68 | Quantification of metoprolol beta 2-adrenoceptor antagonism in asthmatic patients by pharmacokinetic-pharmacodynamic modelling. ( Braat, MC; Jonkers, RE; van Boxtel, CJ, 1992) |
| " Serum creatine kinase activity was compared in 13 patients with brittle asthma currently being treated with subcutaneous terbutaline and an age and sex matched control group of patients with moderate asthma having inhaled treatment only." | 3.68 | Creatine kinase activity in patients with brittle asthma treated with long term subcutaneous terbutaline. ( Ayres, JG; Finnegan, JA; Lawson, N; Sykes, AP, 1991) |
| "Since absorption of nebulized and subcutaneous terbutaline may be delayed or decreased during episodes of severe asthma, a preliminary trial of intravenous terbutaline was instituted in five adult patients with status asthmaticus." | 3.68 | Continuous intravenous terbutaline infusions for adult patients with status asthmaticus. ( Iber, C; O'Connell, MB, 1990) |
| "Forty-four Pediatric Intensive Care Unit (PICU) admissions for acute severe asthma in 27 children between 8/80 and 10/86 were reviewed to determine the safety of prolonged administration of frequently nebulized terbutaline." | 3.68 | Safety of frequent high dose nebulized terbutaline in children with acute severe asthma. ( Katz, R; Kelly, HW; McWilliams, BC; Murphy, S, 1990) |
| "Experiences in combined use of beta-adrenergic stimulants and cardioselective beta-receptor blocker Talinolol are reported in 3 patients in Status Asthmaticus." | 3.67 | [Combined use of talinolol and beta adrenergic stimulants in status asthmaticus. Report on 3 patients]. ( Knappe, J; Oltmanns, G; Schwela, H; Szeszat, S, 1984) |
| "Drug intake and plasma concentrations of theophylline and beta-agonists were recorded in 19 patients with acute asthma (peak expiratory flow rate less than 50% of predicted normal value and heart rate greater than 100 beats/min)." | 3.67 | Drug intake and plasma concentrations in acute asthma. ( Boe, J; Ljungholm, K, 1984) |
| "The efficacy of terbutaline delivered via a 750 ml spacer device (Nebuhaler) compared with a metered dose inhaler alone was studied by means of an open cross-over trial in eight patients with stable asthma." | 3.67 | The efficacy of drug delivery by a pear-shaped spacer and metered dose inhaler. ( Higgins, A; Milledge, JS; Morris, J; Moszoro, H, 1984) |
| "The absorption and excretion profiles of orally administered terbutaline were investigated in 10 asthmatic patients who received a solution containing 5 mg of [3H]terbutaline sulphate." | 3.67 | Oral administration of terbutaline in asthmatic patients. ( Hörnblad, Y; Ripe, E; Tegnér, K, 1984) |
| "Seven asthmatic children (8-12 years) were given terbutaline sulphate intravenously (5." | 3.67 | Kinetics of terbutaline in asthmatic children. ( Hultquist, C; Kjellman, B; Lindberg, C; Nyberg, L; Wettrell, G, 1984) |
| "Nine children, 10-15 years old with chronic asthma, were treated for weekly periods with gradually increasing doses of oral terbutaline sulphate: 45, 79, 118 and 166 micrograms/kg (mean values) 3 times daily." | 3.67 | Oral terbutaline in chronic childhood asthma; effects related to plasma concentrations. ( Foucard, T; Lindström, B; Lönnerholm, G, 1984) |
| "The bronchodilating effect and side-effects of theophylline and a beta 2-adrenoceptor stimulating drug (terbutaline) alone and in combination were studied in 10 adult asthmatic patients." | 3.67 | Simultaneous treatment with terbutaline and theophylline. ( Billing, B; Dahlqvist, R; Garle, M; Hörnblad, Y; Ripe, E, 1984) |
| "Oral terbutaline in gradually increasing doses from 45 to 166 micrograms/kg three times daily was administered to asthmatic school children." | 3.67 | Dose, plasma concentration, and effect of oral terbutaline in long-term treatment of childhood asthma. ( Foucard, T; Lindström, B; Lönnerholm, G, 1984) |
| "Seven asthmatic children were given terbutaline intravenously." | 3.67 | Pharmacokinetics of intravenous terbutaline in asthmatic children. ( Hultquist, C; Kjellman, B; Lindberg, C; Nyberg, L; Wettrell, G, 1989) |
| "The protective effect of pre-exercise treatment with disodium cromoglycate (DC), terbutaline sulphate (TS) and thiazinamium methylsulphate (TM) on exercise-induced asthma (EIA) was investigated." | 3.67 | Comparison of disodium cromoglycate, terbutaline and thiazinamium in the prevention of exercise-induced asthma and its relation to non-specific bronchial responsiveness. ( Berg, WC; Gimeno, F; Steenhuis, EJ; van Veenen, R, 1985) |
| "The bronchodilator effect of three successive stable plasma terbutaline levels was studied in 10 children with asthma." | 3.67 | Dose-response relationships of intravenously administered terbutaline in children with asthma. ( Borgström, L; Fuglsang, G; Pedersen, S, 1989) |
| "A group of 10 patients with chronic asthmatic bronchitis was titrated with slow-release theophylline (Theolin Retard) to a steady state plasma theophylline level of 10 mg/l." | 3.67 | Pharmacodynamics (lung function tests, tremor measurements and cAMP determinations) of a single dose of 0.5 mg terbutaline subcutaneously during sustained-release theophylline medication in patients with asthmatic bronchitis. ( Drost, RH; Fokkens, JK; Hamelink, ML; Kreukniet, J; Maes, RA; van der Vet, AP, 1986) |
| "Twelve children with severe asthma were treated in an intensive care unit with continuously nebulized terbutaline at doses between 1." | 3.67 | Continuous terbutaline nebulization for the treatment of severe exacerbations of asthma in children. ( Aggarwal, J; Portnoy, J, 1988) |
| "We analyzed continuous nebulized terbutaline (CNT) therapy in 19 patients with 27 admissions for severe asthma and impending respiratory failure who failed to respond to our standard asthma protocol of methylprednisolone, aminophylline, and intermittently nebulized terbutaline." | 3.67 | Improvement in clinical asthma score and PaCO2 in children with severe asthma treated with continuously nebulized terbutaline. ( Custer, JR; Hurwitz, ME; Moler, FW, 1988) |
| "In order to localize the main site of action of the beta 2-adrenoceptor selective agonist terbutaline and the beta 1-adrenoceptor selective antagonist atenolol in the airways of asthmatic patients, we compared the effects of these drugs on maximal expiratory flow-volume (MEFV) curves when breathing air and when breathing a helium-oxygen (HeO2) mixture." | 3.67 | Effects of terbutaline and atenolol on large and small airways in asthmatic patients. ( Folgering, HT; Lammers, JW; Müller, ME; van Herwaarden, CL, 1988) |
| "Sixty-eight asthmatics participated in a dose-finding study on bambuterol, a terbutaline prodrug, administered once every evening." | 3.67 | Bambuterol: clinical effects of different doses of a long-acting bronchodilator prodrug. ( Asander, L; Clemmensen, IH; Eklund, G; Gnosspelius, Y; Klarlund Pedersen, B; Persson, G; Ravn, S; Rosenhall, L; Sandström, T; Weeke, B, 1988) |
| "The purpose of this study was to evaluate prospectively the occurrence of cardiac arrhythmias during the combined therapy with intravenous aminophylline and terbutaline in 29 consecutive patients with status asthmaticus." | 3.67 | Cardiac arrhythmias during the combined use of intravenous aminophylline and terbutaline in status asthmaticus. ( Chauvet, JP; Iung, B; Laaban, JP; Proteau, J; Psychoyos, I; Rochemaure, J, 1988) |
| "This is a summary of five pediatric cases of unresponsive status asthmaticus treated with frequent subcutaneous injections of terbutaline." | 3.67 | Frequent parenteral terbutaline in the treatment of status asthmaticus in children. ( Nelson, HS; Tipton, WR, 1987) |
| "In 12, symptom-free, asthmatic children, aged 5-10 years, responses (increases in FEV1) were measured to cumulative doses of inhaled terbutaline delivered by two methods: a) 5 breaths from a 750 ml spacer (Nebuhaler) attached to a metered dose aerosol (doses were 0." | 3.67 | A dose-response study of inhaled terbutaline administered via Nebuhaler or nebuliser to asthmatic children. ( Blackhall, MI; O'Donnell, SR, 1987) |
| "Three out of nine unstable asthmatics whose asthma is subjectively and objectively better controlled on continuous subcutaneous terbutaline infusions (6-12 mg/24 hours) developed tender indurated subcutaneous swellings at the infusion site." | 3.67 | An unusual local reaction to continuous subcutaneous infused terbutaline in unstable asthmatics. ( Cochrane, GM; Hartley, RB; Lewis, LD; O'Driscoll, BR, 1987) |
| "The concentrations of theophylline, terbutaline and salbutamol in post-mortem blood samples from 68 patients (17-85 years old) with asthma or chronic obstructive lung disease, 54 of whom had died of asthma, were analysed." | 3.67 | Post-mortem concentrations of salbutamol, terbutaline and theophylline in asthma patients. ( Boman, G; Lindsjö, M; Lindström, B; Strandberg, K; Wiholm, BE, 1987) |
| " Histamine aerosol significantly increased Rnaw in healthy subjects, asthmatics and asthmatics with allergic rhinitis." | 3.67 | Effects of pulmonary inhalation of water and histamine aerosols on nasal airflow resistance in man. ( Bundgaard, A; Schmidt, A; Syabbalo, NC; Widdicombe, JG, 1986) |
| "The bronchodilatation achieved by the beta 2 agonist terbutaline sulphate given as nebulised aerosol from different devices has been measured in seven patients with mild asthma (mean FEV1 76% predicted) over two hours after inhalation." | 3.67 | Effect of aerosol particle size on bronchodilatation with nebulised terbutaline in asthmatic subjects. ( Clarke, SW; Clay, MM; Pavia, D, 1986) |
| "The study of terbutaline pharmacodynamics in patients with asthma is hampered by interfering stimuli when steady-state methods are employed." | 3.67 | Pharmacokinetic-pharmacodynamic modeling of terbutaline bronchodilation in asthma. ( Braat, MC; Oosterhuis, B; Roos, CM; Van Boxtel, CJ; Wemer, J, 1986) |
| "Terbutaline serum levels, c-AMP plasma levels and percentage improvement in FEV1, were strongly correlated after subcutaneous administration of terbutaline to normals (n = 6) and to asthmatics (n = 5)." | 3.66 | Correlation between terbutaline serum levels, c-AMP plasma levels and FEV1 in normals and asthmatics after subcutaneous administration. ( Bruynzeel, PL; Kreukniet, J; Leferink, JG; Van Den Berg, W, 1980) |
| "Subsensitization of beta-adrenoceptors in airways and lymphocytes developing during 4 to 5 wk of orally administered terbutaline (a long-acting beta 2 selective bronchodilator) was compared in 10 healthy subjects and 11 subjects with mild asthma." | 3.66 | Subsensitization of beta-adrenoceptors in airways and lymphocytes of healthy and asthmatic subjects. ( Abrass, I; Conolly, ME; Deutsch, RI; Hui, KK; Littner, M; Scarpace, P; Tashkin, DP, 1982) |
| "To investigate the effect of glucocorticoids on beta-agonist-induced desensitization, we studied the effect of a single intravenous dose of methylprednisolone (2 mg/kg) on beta-receptor density and affinity in lymphocytes from four normal and four mildly asthmatic subjects at the end of 3 to 5 wk of terbutaline therapy and from four normal subjects taking no other drug." | 3.66 | Reversal of human lymphocyte beta-adrenoceptor desensitization by glucocorticoids. ( Conolly, ME; Hui, KK; Tashkin, DP, 1982) |
| "Repeated finger tremor measurements have been performed in six normal and eight asthmatic subjects after subcutaneous and oral administration of terbutaline." | 3.66 | Tremor measurement in asthma. II. Changes after terbutaline administration suggesting beta-adrenergic blockade. ( Bruynzeel, PL; Fokkens, J; Kreukniet, J; Leferink, JG; Maes, RA; van den Berg, W, 1982) |
| "In five subjects with mild asthma and in five normal subjects, we determined the effect of a 4 wk course of inhaled salbutamol (albuterol), 200 micrograms q." | 3.66 | Selective subsensitization of beta-adrenergic receptors in central airways of asthmatics and normal subjects during long-term therapy with inhaled salbutamol. ( Conolly, ME; Hui, KK; Littner, MR; Tashkin, DP; Wolfe, RN, 1982) |
| "The time course of response to initiation and withdrawal of treatment with terbutaline (5 mg orally, three times daily) was examined in eight normal subjects and 14 asthmatic patients." | 3.66 | Timed effects of an oral adrenergic bronchodilator on pulmonary function and measurements of plasma and leukocyte cyclic AMP: divergence in duration of drug action and development of tolerance. ( Mills, D; Morris, HG; Shepperdson, FT; Sherman, NA; Silvers, WS, 1983) |
| "Plasma terbutaline levels and peak expiratory flow rates were measured in 5 asthmatic children using doses of 0." | 3.66 | Plasma terbutaline levels in asthma. ( Dinwiddie, R; Frame, MH; Gewitz, M; Van der Laag, H, 1983) |
| "The effect of 250 micrograms terbutaline sulphate of three different particle sizes from a metered dose inhaler was examined in ten non-asthmatic and ten asthmatic subjects." | 3.66 | The importance of particle size in response to inhaled bronchodilators. ( Clark, TJ; Morén, F; Rees, PJ, 1982) |
| "Two pregnant patients with a history of migraine each developed evidence of cerebral ischemia while being treated with subcutaneous terbutaline, for asthma in one case and for tocolysis in the other." | 3.66 | Cerebral ischemia associated with parenteral terbutaline use in pregnant migraine patients. ( Benedetti, TJ; Featherstone, HJ; Rosene, KA, 1982) |
| "Eight patients with chronic severe asthma, poorly controlled by conventional doses of inhaled bronchodilator, were treated with high-dose inhaled terbutaline (4 mg four times daily), via either wet nebulisation of terbutaline respirator solution, or by tube-spacer aerosol, using cannisters delivering 1 mg terbutaline per metered dose." | 3.66 | High-dose inhaled terbutaline in the management of chronic severe asthma: comparison of wet nebulisation and tube-spacer delivery. ( Cochrane, GM; Nowell, RV; Prior, JG, 1982) |
| "The bronchodilating properties and side effects of theophylline and a beta 2-adrenoceptor stimulating drug (terbutaline) alone and in combination were studied in 10 adult asthmatic patients." | 3.66 | Separate and combined use of terbutaline and theophylline in asthmatics. Effects related to plasma levels. ( Billing, B; Dahlqvist, R; Garle, M; Hörnblad, Y; Ripe, E, 1982) |
| "A patient developed severe asthma following insulation of her house with urea-formaldehyde foam." | 3.66 | Asthma induced by dust from urea-formaldehyde foam insulating material. ( Filley, WV; Frigas, E; Reed, CE, 1981) |
| "In a cross-over experiment, 16 adult asthmatics slowly inhaled, at functional residual capacity, cumulative doses of terbutaline spray with and without extension of the mouthpiece of the aerosol canister by a cylindrical tube (length 10." | 3.66 | Inhalation of terbutaline spray through an extended mouthpiece: effect on central and peripheral airways. ( Poppius, H, 1980) |
| " An additional 5 patients with traumatic spinal cord injuries and paraplegia received terbutaline for asthma." | 3.66 | Bladder electromyography: response to electric stimulation and to terbutaline. ( Kaplan, PE; Nanninga, JB; Richardson, RR, 1981) |
| "Ten asthmatic children received regular daily therapy with terbutaline aerosol for 50 weeks." | 3.66 | Terbutaline aerosol in the long-term treatment of asthmatic children. ( Blackhall, MI; Macartney, B; O'Donnell, SR, 1981) |
| "We compared pulmonary function in 15 asthmatic subjects before and after ingestion of 5 mg terbutaline and placebo." | 3.66 | Site and duration of bronchodilation in asthmatic patients after oral administration of terbutaline. ( Fairshter, RD; Novey, HS; Wilson, AF, 1981) |
| "Development of beta-receptor desensitization in leucocytes of asthmatics and normals during oral therapy with terbutaline was established by means of in vitro stimulation with terbutaline and isoproterenol." | 3.66 | Desensitization of the beta-adrenergic receptor on leucocytes after long-term oral use of a beta-sympathicomimetic; its effect on the beta-adrenergic blockade hypothesis of Szentivanyi. ( Bruijnzeel, PL; Hamelink, ML; Houben, LA; Kreukniet, J; van den Berg, W; van den Bogaard, W, 1979) |
| "Sixteen patients with bronchial asthma participated in three studies of inhaled terbutaline." | 3.66 | Aerosolized terbutaline in asthmatics. Comparison of dosage strength, schedule, and method of administration. ( Nelson, HS; Petty, WE; Weber, RW, 1979) |
| "The sites of airway obstruction and dilatation after terbutaline administration were studied by inhalation imaging and pulmonary function tests in 12 stable asthmatic patients." | 3.66 | Imaging sites of airway obstruction and measuring functional responses to bronchodilator treatment in asthma. ( Chopra, SK; Elam, D; Taplin, GV; Tashkin, DP; Trevor, E, 1979) |
| "There are many sympathomimetic products available in treatment of asthma, such as ephedrin, isoproterenol, orciprenalin, salbutamol, terbutalin." | 3.66 | [Use of sympathomimetics in the treatment of asthma]. ( Hugues, FC; Julien, D, 1978) |
| "A dose-response study of terbutaline nebulizer solution has been performed in nine convalescent asthmatic patients." | 3.66 | Terbutaline sulphate nebulizer solution: a dose-response study. ( Birrell, DJ; Clarke, CW; May, CS, 1978) |
| "Monolayers of adherent mononuclear leukocytes prepared from normal subjects and asthmatic children whose bronchodilater therapy did not include sympathomimetic drugs, respond to relatively low concentrations of isoproterenol (ISO) and prostaglandin E1 with increased intracellular cyclic adenosine monophosphate (cAMP) levels." | 3.65 | Drug-induced changes of adenylate cyclase activity in cells from asthmatic and nonasthmatic subjects. ( Kalisker, A; Middleton, E; Nelson, HE, 1977) |
| "After a run-in period practolol was given in the dose of 100 mg twice daily to 29 patients with chronic bronchial asthma on the indication hypertension (12) and supraventricular arrhythmia (17)." | 3.65 | Effects of practolol in combination with terbutaline in the treatment of hypertension and arrhythmias in asthmatic patients. ( Eriksson, NE; Formgren, H, 1975) |
| "Complete in vitro dose-response curves for (see article) -isoproterenol (isoprenaline) sulfate showed no functional defects in bronchial muscular beta-adrenergic receptors in three patients with chronic intrinsic asthma, as compared to 60 patients with normal pulmonary function." | 3.65 | Development of "resistance" in beta-adrenergic receptors of asthmatic patients. ( Larsson, SA; Svedmyr, NL; Thiringer, GK, 1976) |
| " Adverse events (AEs), serious AEs (SAEs), discontinuations due to AEs (DAEs), and study-defined asthma-related discontinuations from corresponding treatment groups in both studies were pooled." | 3.01 | Safety of As-Needed Budesonide-Formoterol in Mild Asthma: Data from the Two Phase III SYGMA Studies. ( Alagappan, VKT; Barnes, PJ; Bateman, ED; Emerath, U; FitzGerald, JM; Ivanov, S; Jansen, G; Lamarca, R; Larsdotter, U; O'Byrne, PM; Puu, M; Reddel, HK; Surmont, F; Zheng, J, 2021) |
| "Terbutaline is a prohibited drug except for athletes with a therapeutic use exemption certificate; terbutaline's effects on endurance performance are relatively unknown." | 2.90 | The Effects of Inhaled Terbutaline on 3-km Running Time-Trial Performance. ( Chester, NJ; Dickinson, JW; Loosemore, M; Molphy, J; Whyte, G, 2019) |
| "10 U kg(-1) inhaled human insulin was administered on each dosing day with or without prior administration of the bronchodilator terbutaline (in random order)." | 2.75 | The effect of terbutaline on the absorption of pulmonary administered insulin in subjects with asthma. ( Köhler, G; Korsatko, S; Olschewski, H; Petersen, AH; Pieber, TR; Råstam, J; Sparre, T; Wollmer, P; Wutte, A, 2010) |
| " The clinical condition scores, frequency of attacks and dosage of Terbutaline inhaled were scored and recorded on the first day of hospitalization (before treatment) and after treatment." | 2.73 | Effect of ligustrazine injection on levels of interleukin-4 and interferon-gamma in patients with bronchial asthma. ( Che, XW; Wang, H; Wang, W; Zhang, Y, 2008) |
| "terbutaline and there were no significant differences between Arg-16 and Gly-16 individuals in this respect." | 2.73 | The influence of the AA 16 beta 2-adrenoceptor polymorphism on systemic and airway responses in asthma. ( Jansen, HM; Jonkers, RE; van Veen, A; Weller, FR; Wierenga, EA, 2008) |
| " Dose-response curves were compared using an analysis of covariance." | 2.69 | Tolerance to beta-agonists during acute bronchoconstriction. ( Aldridge, RE; Cowan, JO; Flannery, EM; Hancox, RJ; Herbison, GP; McLachlan, CR; Taylor, DR; Town, GI, 1999) |
| " The primary objective was to evaluate safety (pulse rate, blood pressure, adverse events, hematology, and clinical chemistry)." | 2.69 | One-year safety study with bambuterol once daily and terbutaline three times daily in 2-12-year-old children with asthma. The Bambuterol Multicentre Study Group. ( Kuusela, AL; Marenk, M; Olsson, H; Persson, B; Sandahl, G; Valovirta, E; Zarkovic, JP, 2000) |
| "Terbutaline was ineffective by these criteria." | 2.69 | Detection and treatment of early asthma. ( Björkstén, F; Haahtela, T; Kilpiö, K; Kiviranta, K; Metso, T, 2000) |
| "Pretreatment with terbutaline did produce small but nonsignificant increases in aerobic fractional utilization (percent peak VO2 on drug: 65." | 2.67 | Beta 2-agonists and running economy in prepubertal boys. ( Aitchison, TC; Paton, JY; Thomson, KJ; Unnithan, VB, 1994) |
| " Of 25 subjects whose control differed significantly between treatments with baseline vs increased corticosteroid, 22 (88 percent) favored the increased dosage (p < 0." | 2.67 | Increased inhaled bronchodilator vs increased inhaled corticosteroid in the control of moderate asthma. ( Flannery, EM; Herbison, GP; Lake, DC; Print, CG; Sears, MR; Taylor, DR, 1992) |
| "Terbutaline was administered four times daily via Nebuhaler/MDI or nebuliser." | 2.67 | Nebuhaler versus wet aerosol for domiciliary bronchodilator therapy. A multi-centre clinical comparison. ( Antic, R; Armstrong, JG; Francis, PW; Landau, LI; Le Souef, PN; Martin, AJ; McDonald, CF; Mitchell, CA; Musk, AW; Pierce, RJ, 1992) |
| " The study showed improved bronchodilation when PEP was combined with inhalation of beta 2-agonist compared with beta 2-agonist alone." | 2.67 | Treatment of bronchial asthma with terbutaline inhaled by conespacer combined with positive expiratory pressure mask. ( Dahl, R; Frischknecht-Christensen, E; Nørregaard, O, 1991) |
| "Tulobuterol is a synthetic beta-adrenergic agonist which, when administered orally, is a potent, long-acting bronchodilator." | 2.67 | Can a new beta 2-agonist reduce the mortality of asthma? ( Aldons, PM, 1990) |
| "Tulobuterol is a new synthetic beta 2-agonist with potent and prolonged bronchodilator activity when given by oral and inhaled routes." | 2.67 | Prolonged treatment with oral and inhaled tulobuterol does not induce airways tachyphlaxis. ( Patel, KR, 1990) |
| "Treatment with terbutaline in Turbuhaler was preferred by a majority of children and parents." | 2.67 | Comparison of Bricanyl Turbuhaler and Berotec dry powder inhaler. ( Ribeiro, LB; Wirén, JE, 1990) |
| " Eight patients with extrinsic and 10 patients with intrinsic asthma deprived of oral bronchodilator treatment and corticosteroids for at least a week, and in a clinically stable condition, 10 patients with extrinsic rhinitis and on no treatment, as well as age and sex matched healthy control subjects showed almost identical dose-response relations for the inhibitory effect of intradermally injected terbutaline (0." | 2.66 | Equivalent inhibition by terbutaline of anti-human IgE skin responses in atopic and non-atopic subjects. ( Grönneberg, R; Stålenheim, G; Strandberg, K; Zetterström, O, 1985) |
| " The slow-release tablets were preferred by 15 of 18 children and their families when the effects, side effects and dosage were evaluated." | 2.66 | Terbutaline slow-release tablets in children with asthma. A comparison with t.i.d. beta 2-agonist therapy. ( Croner, S; Gustafsson, M; Kjellman, NI; Säwedal, L, 1986) |
| "The pharmacokinetic mechanism of the theophylline-terbutaline interaction has been studied." | 2.66 | Increased theophylline clearance in asthmatic patients due to terbutaline. ( Garty, M; Ilfeld, DN; Mazar, A; Paul-Keslin, L; Rosenfeld, JB; Spitzer, S, 1989) |
| "Nine adult patients with bronchial asthma participated." | 2.66 | Turbuhaler: a new device for dry powder terbutaline inhalation. ( Johnsen, CR; Weeke, ER, 1988) |
| "Bambuterol is a prodrug, from which terbutaline is slowly generated." | 2.66 | Comparison between a new once-daily, bronchodilating drug, bambuterol, and terbutaline sustained-release, twice daily. ( Anehus, S; Gnosspelius, Y; Persson, G, 1988) |
| "Enprofylline is a novel xanthine derivative with negligible adenosine antagonizing ability." | 2.66 | Additive bronchodilator effects of terbutaline and enprofylline in asthma. ( Lunell, E; Rasmussen, JB, 1987) |
| "KWD 2131 is a new beta-agonist with preferably anti allergic property." | 2.65 | Inhibitory effect of KWD 2131, terbutaline, and DSCG on the immediate and late allergen-induced bronchoconstriction. ( Hegardt, B; Pauwels, R; Van Der Straeten, M, 1981) |
| " After the terbutaline dose-response curve was determined, terbutaline was inhaled three times in increasing doses." | 2.65 | Pafenolol, a highly selective beta 1-adrenoceptor-antagonist, in asthmatic patients: interaction with terbutaline. ( Löfdahl, CG; Marlin, GE; Svedmyr, N, 1983) |
| " Inhaled beta-2-agonists were found to give better protection against EIA than intramuscular dosed beta-2-agonists." | 2.65 | Exercise-induced asthma - laboratory observations. ( Bundgaard, A, 1983) |
| "Twenty-five patients with chronic bronchial asthma completed the trial." | 2.65 | A comparison of sustained-release terbutaline with ordinary salbutamol in bronchial asthma. ( Beskow, R; Ericsson, CH; Grönneberg, R; Sjögren, I; Skedinger, M, 1984) |
| " This study indicates that the bronchodilating effect of terbutaline administered via the spacer is dose-dependent at the first inhalation, and that succeeding inhalations show no dose-response effects." | 2.65 | Cumulative dose response study comparing clinical effects of two doses of terbutaline sulphate administered via a 750 ml spacer to asthmatic patients. ( Franck, K; Laursen, LC; Munch, EP; Taudorf, E; Weeke, B, 1984) |
| "125 mg given intramuscularly, while this dosage elicited maximal bronchodilator effect." | 2.65 | Cardiovascular effects of intramuscular or inhaled terbutaline in asthmatics. ( Buch, J; Bundgaard, A, 1984) |
| "Both terbutaline treatments resulted in a significant increase in forced expiratory volume in one second, as compared with placebo (P less than 0." | 2.65 | Aerosol treatment of bronchoconstriction in children, with or without a tube spacer. ( Pedersen, S, 1983) |
| "A sustained release preparation of terbutaline sulphate has been formulated (Bricanyl depot tablets) in order to extend the duration and accordingly change the dosage regimen to twice a day." | 2.65 | Terbutaline depot tablets in asthma. A clinical evaluation. ( Bundgaard, A; Fagerström, PO; Taudorf, E; Weeke, B; Weeke, E, 1981) |
| " Our findings suggest that the two effects have different dose-response relationships, with higher doses of adrenergic agonists needed to prevent EIA than to maintain bronchodilation." | 2.65 | Bronchodilation and inhibition of induced asthma by adrenergic agonists. ( Beasley, PP; Eggleston, PA, 1981) |
| "Terbutaline is a safe bronchodilator drug when administered orally in 2." | 2.65 | Safety and effectiveness of terbutaline in children with chronic asthma. ( Gavani, UD; Hyde, JS; Khurana, S; Manaligod, LM, 1979) |
| "Terbutaline (5 mg) was found to be an effective bronchodilator with minimal side effects and an earlier onset and longer duration of action than ephedrine (25 mg)." | 2.64 | Evaluation of a new oral beta2-adrenoceptor stimulant bronchodilator, terbutaline. ( Gast, LR; Geumei, A; Miller, WF; Paez, PN, 1975) |
| "50 mg terbutaline aerosol used on a regular dosage schedule over a six-week period." | 2.64 | Aerosolized terbutaline sulfate--an evalution of efficacy and side effects in patients with reversible airway disease. ( Allegra, J; Gillin, M; Trautlein, J, 1977) |
| "25 mg/puff) when administered as metered aerosol in a dosage of one puff followed by two puffs 30 min later produced the same maximum improvement of ventilatory function." | 2.64 | Hexoprenaline and terbutaline administered by inhalation. A comparison between two beta2-adrenoreceptor agonists with respect to effect on bronchial obstruction, heart rate, blood pressure and muscle tremor. ( Hörnblad, Y; Leideman, T; Ripe, E, 1978) |
| "The aim of this review is to assess the risk of fatal and non-fatal serious adverse events in trials that randomised patients with chronic asthma to regular formoterol versus placebo or regular short-acting beta(2)-agonists." | 2.48 | Regular treatment with formoterol for chronic asthma: serious adverse events. ( Cates, CJ; Cates, MJ, 2012) |
| "For the acute COPD studies, one was double-blind and randomised, one was single-blind and randomised, and one was open-label." | 2.45 | Use of dry powder inhalers in acute exacerbations of asthma and COPD. ( Borgström, L; Ingelf, J; Selroos, O, 2009) |
| " Usually, oral dosage forms of beta 2-agonists have been used, but side effects such as palpitation and tremor have been reported because of excessive serum levels around Tmax." | 2.41 | [Development of transdermal formulation of tulobuterol for the treatment of bronchial asthma]. ( Kato, H; Nagata, O; Nakano, Y; Suzuki, T; Yamazaki, M, 2002) |
| " When chronic symptoms necessitate maintenance treatment, the frequency of dosing may become a deciding factor in the selection of a bronchodilator." | 2.37 | Tulobuterol in the management of obstructive airways disease in adults. ( Patel, KR, 1985) |
| " Initial findings from studies of unequal (morning versus evening) BID dosing schedules--more theophylline or terbutaline before bed-time than arising--reveal a better therapeutic advantage relative to equal BID dosing schedules for those patients with predominantly nocturnal symptoms." | 2.37 | Chronobiology and asthma. II. Body-time-dependent differences in the kinetics and effects of bronchodilator medications. ( McGovern, JP; Reinberg, A; Scott, PH; Smolensky, MH, 1987) |
| "Occasionally, segmental or subsegmental atelectasis develops, but in most series radiographically visible atelectasis is uncommon." | 2.37 | Clinical aspects of mucus and mucous plugging in asthma. ( Fanta, CH, 1985) |
| "Bronchial asthma is a chronic disease which is currently treated using various inhalants." | 1.62 | Sustained release of tulobuterol from graphene oxide laden hydrogel to manage asthma. ( Chen, Y; Jin, S; Luo, L; Luo, S; Wu, B; Xu, C; Yang, T, 2021) |
| " However, this side effect may be complicated by a tachypnea compensating for metabolic acidosis and should be known to avoid unnecessary therapeutic escalation." | 1.51 | [Hyperlactatemia induced by inhaled β2 agonists: An underrecognized side effect. Report of two cases]. ( David, C; Pouchot, J; Ranque, B, 2019) |
| "Persistent cough is a frequent cause of doctor and hospital visits, and its incidence may be increasing." | 1.39 | Cough variant and cough-predominant asthma are major causes of persistent cough: a multicenter study in Japan. ( Adachi, M; Akiyama, K; Hasegawa, M; Inoue, H; Kimura, G; Kobayashi, H; Niimi, A; Ohbayashi, H; Sagara, H; Takahashi, K; Wakayama, T; Yamauchi, K; Yokoe, T, 2013) |
| "Lactic acidosis is a marker of tissue hypoperfusion and impairs oxygen delivery." | 1.38 | Lactic acidosis as a complication of β-adrenergic aerosols. ( Bobbia, X; Boutin, C; Claret, PG; de la Coussaye, JE; Rougier, M, 2012) |
| "Anti-asthmatic agents could alleviate pulmonary edema through upregulating the expression of AQP1 and AQP5 in mouse lungs that have OVA-induced asthma." | 1.38 | Anti-asthmatic agents alleviate pulmonary edema by upregulating AQP1 and AQP5 expression in the lungs of mice with OVA-induced asthma. ( Bai, C; Dong, C; Huang, H; Li, B; Ma, Z; Wang, G; Wang, X; Xiao, K, 2012) |
| " Our findings suggested that the initial dosage of theophylline should be adjusted according to the gender of pediatric patients and particularly in the case of infants." | 1.35 | Effect of gender on theophylline clearance in the asthmatic acute phase in Japanese pediatric patients. ( Igarashi, T; Iwakawa, S, 2009) |
| "We suggest that this treatment of bronchial asthma may protect against endotoxin contained in inhaled house dust." | 1.35 | Tulobuterol patch maintains diaphragm muscle contractility for over twenty-four hours in a mouse model of sepsis. ( Miura, M; Murakami, Y; Nishio, T; Sasaki, K; Shindoh, C; Shishido, R, 2009) |
| "The prevalence of bronchial asthma is 4-8% among pregnant women." | 1.33 | [The management of bronchial asthma during pregnancy--Hungarian experiences]. ( Bohács, A; Losonczy, G; Magyar, P; Pállinger, E; Rigó, J; Tamási, L, 2005) |
| "Wheezing is a common clinical finding in patients with asthma and COPD during episodes of severe airway obstruction, and can also be heard in normal subjects during forced expiratory maneuvers; however, the properties of wheezing are difficult to perceive and quantify during auscultation." | 1.31 | Detection of wheezing during maximal forced exhalation in patients with obstructed airways. ( Fiz, JA; García, MA; Homs, A; Izquierdo, J; Jané, R; Morera, J, 2002) |
| " Pharmacokinetic analysis indicated that absorption of bambuterol was slow and multi-phasic and that slow biotransformation to terbutaline occurred both presystemically and systemically." | 1.31 | Clinical-pharmacokinetic aspects of prolonged effect duration as illustrated by beta2-agonists. ( Rosenburg, J, 2002) |
| "2." | 1.31 | Effects of sustained-release tulobuterol on asthma control and beta-adrenoceptor function. ( Ito, Y; Kondo, M; Kume, H; Suzuki, R; Takagi, K; Yamaki, K, 2002) |
| "terbutaline because of bronchoconstriction (dosage not documented)." | 1.30 | [Acute theophylline intoxication as differential diagnosis of pneumothorax in an asthma patient]. ( Schaarschmidt, S; Standl, T, 1997) |
| " The accuracy of dosing and the technically perfect use of devices are extremely important, especially when drugs with potential systemic side effects are administered." | 1.30 | Inhalation devices in childhood asthma. ( Gács, E; Göndöcs, R; Jákly, A; Uhereczky, G, 1998) |
| "Seventeen asthmatic patients with acute airway obstruction had either IT or eFE on 2 consecutive days." | 1.29 | 'Functional relaxation' reduces acute airway obstruction in asthmatics as effectively as inhaled terbutaline. ( Hahn, EG; Loew, TH; Martus, P; Siegfried, W; Tritt, K, 1996) |
| " During the high dosing the secretion rate of parotid saliva decreased and the concentrations of its total protein, amylase, hexosamine and the ratio of hexosamine/total protein were lowered." | 1.28 | Saliva composition in asthmatic patients after treatment with two dose levels of a beta 2-adrenoceptor agonist. ( Ericson, T; Möller, C; Ryberg, M, 1990) |
| " This study emphasizes the need for individual dosing of inhaled bronchodilators." | 1.28 | The bronchodilator response from increasing doses of terbutaline inhaled from a multi-dose powder inhaler (Turbuhaler). ( Persson, G; Wirén, JE, 1990) |
| "Forty-seven patients with allergic bronchial asthma were challenged with the relevant allergen." | 1.28 | Factors influencing the occurrence of late bronchial reactions after allergen challenge. ( Machado, L; Stålenheim, G, 1990) |
| " The dose-response curves of terbutaline on isolated tracheae of actively sensitized guinea pigs were significantly shifted to the right in comparison with control trachea (ED50 11." | 1.27 | Mechanical and biochemical alterations in guinea-pig tracheae caused by sensitisation. ( Beier, W; Feddersen, C; Kaukel, E; Koppermann, G; Schrum, C, 1984) |
| " A dose-response study with inhaled terbutaline in six patients before and after 4 weeks of nebulizer treatment showed no evidence of a decline in response." | 1.27 | Home nebulizers in severe chronic asthma. ( Davies, D; Macfarlane, J; McGivern, DV; Revill, S; Sechiari, A; Ward, M, 1984) |
| " Dose-response curves were plotted upon the inhalation of salbutamol in two-week intervals in patients treated with betamimetics." | 1.27 | Development of drug tachyphylaxis in asthmatic patients treated with beta-adrenergic drugs. ( Böszörményi-Nagy, G; Debreczeni, LA; Herjavecz, I; Szeitz, A, 1987) |
| " There was a significant decrease in the density of beta-adrenoceptors following chronic administration of terbutaline." | 1.27 | Ketotifen prevents terbutaline-induced down-regulation of beta-adrenoceptors in guinea pig lung. ( Agrawal, DK; Koshino, T; Townley, RG; Townley, TA, 1988) |
| "Terbutaline sulfate has been selected as a suitable compound for evaluation of this inhaler." | 1.27 | Turbuhaler: a new powder inhaler for administration of drugs to the airways. ( Wetterlin, K, 1988) |
| "The slow disappearance of the arrhythmia is a result of the prolonged half-life of theophylline in the fetus." | 1.27 | [Fetal bigeminus following combined bronchodilator treatment of the mother]. ( Neeb, U, 1986) |
| "Pretreatment with lidocaine, the beta-receptor agonist, terbutaline, or the adenosine non-blocking xanthine, enprofylline, inhibited the capsaicine induced inflammatory response." | 1.27 | Anti-asthma drugs and capsaicine-induced microvascular effects in lower airways. ( Erjefält, I; Persson, CG, 1985) |
| " Thus, although there are differences in routes of metabolism, the selectivity of action within the airways when the drugs are inhaled is to a large part dependent on pharmacokinetic and metabolic factors." | 1.26 | Pharmacokinetic studies with inhaled drugs. ( Davies, DS, 1982) |
| " Some important parameters are the biological half-life at 3." | 1.26 | Pharmacokinetics of terbutaline, a beta 2-sympathomimetic, in healthy volunteers and asthmatic patients. ( Kreukniet, J; Leferink, JG; Maes, RA; van den Berg, W; Wagemaker-Engels, I, 1982) |
| " Neither an acute loading dose nor chronic administration of either drug singly produced significant changes in wheal size in response to histamine, ragweed, or grass allergens." | 1.26 | Effect of theophylline and terbutaline on immediate skin tests. ( Chipps, BE; Lichtenstein, LM; Norman, PS; Sanders, JP; Sobotka, AK; Teets, KC, 1980) |
| " The receptors were tested by infusion of increasing doses of isoprenaline, so that dose-response curves for isoprenaline were recorded." | 1.26 | Lack of bronchial beta adrenoceptor resistance in asthmatics during long-term treatment with terbutaline. ( Larsson, S; Svedmyr, N; Thiringer, G, 1977) |
| " Tachycardia is a side effect which limits dosage in a few patients only." | 1.26 | Comparison of infused and inhaled terbutaline in patients with asthma. ( Svedmyr, N; Thiringer, G, 1976) |
| " The dose-response curves obtained during infusions of beta-adrenergic-stimulating drugs are linearly related to the dose given and are highly reproducible." | 1.25 | Evaluation of skeletal muscle tremor due to bronchodilator agents. ( Svedmyr, N; Thiringer, G, 1975) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 474 (57.52) | 18.7374 |
| 1990's | 184 (22.33) | 18.2507 |
| 2000's | 98 (11.89) | 29.6817 |
| 2010's | 52 (6.31) | 24.3611 |
| 2020's | 16 (1.94) | 2.80 |
| Authors | Studies |
|---|---|
| Sultan, K | 1 |
| Zamir, A | 1 |
| Ashraf, W | 1 |
| Imran, I | 1 |
| Saeed, H | 1 |
| Rehman, AU | 1 |
| Majeed, A | 1 |
| Rasool, MF | 1 |
| Sriprasart, T | 1 |
| Waterer, G | 1 |
| Garcia, G | 1 |
| Rubin, A | 1 |
| Andrade, MAL | 1 |
| Roguska, A | 1 |
| Phansalkar, A | 1 |
| Fulmali, S | 1 |
| Martin, A | 1 |
| Mittal, L | 1 |
| Aggarwal, B | 1 |
| Levy, G | 1 |
| Carvajal Gonczi, CM | 1 |
| Hajiaghayi, M | 1 |
| Gholizadeh, F | 1 |
| Xavier Soares, MA | 1 |
| Touma, F | 1 |
| Lopez Naranjo, C | 1 |
| Rios, AJ | 1 |
| Pozzebon, C | 1 |
| Daigneault, T | 1 |
| Burchell-Reyes, K | 1 |
| Darlington, PJ | 1 |
| Hardy, J | 2 |
| Baggott, C | 3 |
| Fingleton, J | 3 |
| Reddel, HK | 7 |
| Hancox, RJ | 11 |
| Harwood, M | 2 |
| Corin, A | 1 |
| Sparks, J | 2 |
| Hall, D | 1 |
| Sabbagh, D | 1 |
| Mane, S | 1 |
| Vohlidkova, A | 1 |
| Martindale, J | 1 |
| Williams, M | 1 |
| Shirtcliffe, P | 1 |
| Holliday, M | 3 |
| Weatherall, M | 3 |
| Beasley, R | 3 |
| Gauthier, M | 1 |
| Wenzel, SE | 1 |
| Lai, K | 2 |
| Yi, F | 2 |
| Han, L | 2 |
| Liu, B | 2 |
| Zhang, X | 2 |
| Xue, Y | 2 |
| Luo, W | 2 |
| Chen, Q | 2 |
| Stone, RG | 1 |
| McDonald, M | 1 |
| Elnazir, B | 1 |
| Zhang, O | 1 |
| Minku, LL | 1 |
| Gonem, S | 1 |
| Hansen, P | 1 |
| Hardy, JK | 1 |
| Mohamed, S | 1 |
| Nasr, M | 1 |
| Salama, A | 1 |
| Refai, H | 1 |
| Tewhaiti-Smith, J | 1 |
| Semprini, A | 1 |
| Adair, E | 1 |
| Dibaba, D | 1 |
| Fowke, JH | 1 |
| Snider, M | 1 |
| Luo, S | 1 |
| Jin, S | 1 |
| Yang, T | 1 |
| Wu, B | 1 |
| Xu, C | 1 |
| Luo, L | 1 |
| Chen, Y | 1 |
| FitzGerald, JM | 5 |
| O'Byrne, PM | 7 |
| Bateman, ED | 5 |
| Barnes, PJ | 10 |
| Zheng, J | 2 |
| Ivanov, S | 4 |
| Lamarca, R | 4 |
| Larsdotter, U | 1 |
| Emerath, U | 1 |
| Jansen, G | 1 |
| Puu, M | 2 |
| Alagappan, VKT | 2 |
| Surmont, F | 1 |
| Crossingham, I | 1 |
| Turner, S | 1 |
| Ramakrishnan, S | 1 |
| Fries, A | 1 |
| Gowell, M | 1 |
| Yasmin, F | 1 |
| Richardson, R | 1 |
| Webb, P | 1 |
| O'Boyle, E | 1 |
| Hinks, TS | 1 |
| Kirby, T | 1 |
| Jenkins, CR | 1 |
| Eriksson, G | 1 |
| Sears, MR | 5 |
| Lindberg, M | 1 |
| Buhl, LF | 1 |
| Pedersen, FN | 1 |
| Andersen, MS | 1 |
| Glintborg, D | 1 |
| Zhong, N | 2 |
| Keen, C | 2 |
| Jorup, C | 4 |
| Siwek-Posluszna, A | 1 |
| Steurer, J | 2 |
| Stanbrook, MB | 1 |
| Ruihong, Z | 1 |
| Lu, W | 1 |
| Xiaoli, L | 1 |
| David, C | 1 |
| Pouchot, J | 1 |
| Ranque, B | 1 |
| Molphy, J | 1 |
| Dickinson, JW | 1 |
| Chester, NJ | 1 |
| Loosemore, M | 1 |
| Whyte, G | 1 |
| Park, HS | 1 |
| Yoon, D | 1 |
| Lee, HY | 2 |
| Ban, GY | 1 |
| Wan Yau Ming, S | 1 |
| Jie, JLZ | 1 |
| Carter, V | 1 |
| Hardjojo, A | 1 |
| Van Boven, JFM | 1 |
| Price, DB | 1 |
| Wang, W | 2 |
| Liu, QB | 1 |
| Jing, W | 1 |
| Beng, H | 1 |
| Su, H | 1 |
| Wang, S | 1 |
| Kuai, Y | 1 |
| Hu, J | 1 |
| Zhang, R | 1 |
| Liu, F | 1 |
| Tan, W | 1 |
| Hong, JG | 1 |
| Li, Z | 1 |
| Cates, CJ | 5 |
| Karner, C | 1 |
| Lin, Q | 1 |
| Liu, QH | 1 |
| Bao, YX | 1 |
| Niimi, A | 2 |
| Ohbayashi, H | 1 |
| Sagara, H | 1 |
| Yamauchi, K | 1 |
| Akiyama, K | 2 |
| Takahashi, K | 1 |
| Inoue, H | 2 |
| Wakayama, T | 1 |
| Kobayashi, H | 1 |
| Hasegawa, M | 1 |
| Kimura, G | 1 |
| Yokoe, T | 1 |
| Adachi, M | 2 |
| Moustafa, F | 1 |
| Garrouste, C | 1 |
| Bertrand, PM | 1 |
| Kauffmann, S | 1 |
| Schmidt, J | 1 |
| Doymaz, S | 2 |
| Schneider, J | 2 |
| Sagy, M | 1 |
| Kantor, DB | 1 |
| Phipatanakul, W | 1 |
| Carroll, CL | 2 |
| Coro, M | 1 |
| Cowl, A | 1 |
| Sala, KA | 1 |
| Schramm, CM | 2 |
| Mansur, AH | 1 |
| Afridi, L | 1 |
| Sullivan, J | 1 |
| Ayres, JG | 6 |
| Wilson, D | 1 |
| Singhi, S | 1 |
| Grover, S | 1 |
| Bansal, A | 1 |
| Chopra, K | 1 |
| Lin, CH | 1 |
| Hsu, JY | 1 |
| Hsiao, YH | 1 |
| Tseng, CM | 1 |
| Su, VY | 1 |
| Chen, YH | 1 |
| Yang, SN | 1 |
| Lee, YC | 1 |
| Su, KC | 1 |
| Perng, DW | 1 |
| Kerstjens, HAM | 1 |
| van den Berge, M | 1 |
| Papi, A | 1 |
| Marku, B | 1 |
| Scichilone, N | 1 |
| Maestrelli, P | 1 |
| Paggiaro, P | 1 |
| Saetta, M | 1 |
| Nava, S | 1 |
| Folletti, I | 1 |
| Bertorelli, G | 1 |
| Bertacco, S | 1 |
| Contoli, M | 1 |
| Plebani, M | 1 |
| Barbaro, MPF | 1 |
| Spanevello, A | 1 |
| Aliani, M | 1 |
| Pannacci, M | 1 |
| Morelli, P | 1 |
| Beghé, B | 1 |
| Fabbri, LM | 1 |
| Bussienne, F | 1 |
| Maillot, A | 1 |
| Reynaud, T | 1 |
| Jacobson, GA | 1 |
| Hostrup, M | 2 |
| Matsumoto, H | 1 |
| Ito, I | 1 |
| Oguma, T | 1 |
| Otsuka, K | 1 |
| Takeda, T | 1 |
| Nakaji, H | 1 |
| Tajiri, T | 1 |
| Iwata, T | 1 |
| Nagasaki, T | 1 |
| Mishima, M | 1 |
| Miller, E | 1 |
| Ställberg, B | 2 |
| Ekström, T | 5 |
| Neij, F | 1 |
| Olsson, P | 1 |
| Skoogh, BE | 1 |
| Wennergren, G | 1 |
| Löfdahl, CG | 13 |
| Volovitz, B | 1 |
| Bilavsky, E | 1 |
| Nussinovitch, M | 1 |
| Che, XW | 1 |
| Zhang, Y | 1 |
| Wang, H | 2 |
| Lasserson, TJ | 2 |
| Igarashi, T | 1 |
| Iwakawa, S | 1 |
| Chan, CK | 1 |
| Kuo, ML | 1 |
| Yeh, KW | 1 |
| Ou, LS | 1 |
| Chen, LC | 1 |
| Yao, TC | 1 |
| Huang, JL | 1 |
| Selroos, O | 7 |
| Borgström, L | 4 |
| Ingelf, J | 1 |
| Shindoh, C | 1 |
| Murakami, Y | 1 |
| Shishido, R | 1 |
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| Nishio, T | 1 |
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| Terada, M | 1 |
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| Bussamra, MH | 1 |
| Stelmach, R | 1 |
| Rodrigues, JC | 1 |
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| van Dalen, CJ | 1 |
| Aldridge, RE | 5 |
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| Senthilmohan, R | 1 |
| Cowan, JO | 6 |
| Taylor, DR | 10 |
| Town, GI | 5 |
| Kettle, AJ | 1 |
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| Tamminen, K | 1 |
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| de la Coussaye, JE | 1 |
| Wang, G | 2 |
| Liu, Y | 1 |
| Yang, M | 2 |
| Liu, S | 1 |
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| Agertoft, L | 3 |
| Pedersen, S | 16 |
| Nordvall, SL | 1 |
| Pedroletti, C | 1 |
| Bengtsson, T | 3 |
| Johannes-Hellberg, I | 1 |
| Rosenborg, J | 3 |
| Chandra, P | 1 |
| Paliwal, L | 1 |
| Lodha, R | 2 |
| Kabra, SK | 2 |
| Straub, DA | 1 |
| Minocchieri, S | 1 |
| Moeller, A | 1 |
| Hamacher, J | 1 |
| Wildhaber, JH | 1 |
| Chuchalin, A | 1 |
| Kasl, M | 1 |
| Nihlen, U | 1 |
| Raison-Peyron, N | 1 |
| Co Minh, HB | 1 |
| Vidal-Mazuy, A | 1 |
| Guilhou, JJ | 1 |
| Guillot, B | 1 |
| Burioka, N | 1 |
| Miyata, M | 1 |
| Endo, M | 1 |
| Fukuoka, Y | 1 |
| Suyama, H | 1 |
| Nakazaki, H | 1 |
| Igawa, K | 1 |
| Shimizu, E | 1 |
| Shaw, J | 1 |
| Yang, IA | 1 |
| Moreno-Ancillo, A | 1 |
| Gil-Adrados, AC | 1 |
| Domínguez-Noche, C | 1 |
| Cosmes, PM | 1 |
| Kambalapalli, M | 1 |
| Nichani, S | 1 |
| Upadhyayula, S | 1 |
| Tamási, L | 1 |
| Bohács, A | 1 |
| Pállinger, E | 1 |
| Rigó, J | 1 |
| Magyar, P | 2 |
| Losonczy, G | 1 |
| Sannier, N | 1 |
| Timsit, S | 1 |
| Cojocaru, B | 1 |
| Leis, A | 1 |
| Wille, C | 1 |
| Garel, D | 1 |
| Bocquet, N | 1 |
| Chéron, G | 1 |
| Tsai, YG | 2 |
| Yang, KD | 2 |
| Hung, CH | 2 |
| Balatsouras, DG | 1 |
| Eliopoulos, P | 1 |
| Rallis, E | 1 |
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| Corre, KA | 1 |
| Rothstein, RJ | 1 |
| Arne, M | 1 |
| Sjölund, K | 1 |
| Uden, DL | 1 |
| Goetz, DR | 1 |
| Kohen, DP | 1 |
| Fifield, GC | 1 |
| Beasley, CR | 1 |
| O'Donnell, TV | 1 |
| Foged, N | 1 |
| Høst, A | 1 |
| Fanta, CH | 1 |
| Faurschou, P | 1 |
| Margulies, JL | 1 |
| Kallus, L | 1 |
| Yamate, M | 1 |
| Biedermann, AA | 1 |
| Chu, TJ | 1 |
| Danziger, Y | 1 |
| Volwitz, B | 1 |
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| Sennhauser, F | 1 |
| Schoeni, M | 1 |
| Aelony, Y | 1 |
| vd Mark, TW | 1 |
| Becker, AB | 1 |
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| von Wichert, P | 1 |
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| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Comparison of Symbicort® SMART (160/4.5μg) and Symbicort® Turbuhaler 160/4.5 μg, Plus Terbutaline Turbuhaler 0.4 mg as Needed, for Treatment of Asthma - a 12-month, Randomized, Double-blind, Parallel Group, Active-controlled, Multinational Phase III Stu[NCT00839800] | Phase 3 | 2,091 participants (Actual) | Interventional | 2009-02-28 | Completed | ||
| A Clinical Study Comparing Symbicort 'as Needed' With Pulmicort Twice Daily Plus Terbutaline 'as Needed' in Adult and Adolescent Patients With Asthma[NCT02224157] | Phase 3 | 4,215 participants (Actual) | Interventional | 2014-11-28 | Completed | ||
| A Clinical Study Comparing Symbicort® 'as Needed' With Terbutaline 'as Needed' and With Pulmicort® Twice Daily Plus Terbutaline 'as Needed' in Adult and Adolescent Patients With Asthma.[NCT02149199] | Phase 3 | 3,850 participants (Actual) | Interventional | 2014-07-07 | Completed | ||
| A Randomized, Open-labeled, Multicenter Clinical Trial to Compare the Efficacy and Safety of On-demand and Continuous Administration of Nasal Spray in the Treatment of Moderate-to-severe Persistent Allergic Rhinitis[NCT05080322] | Phase 4 | 150 participants (Anticipated) | Interventional | 2023-02-10 | Recruiting | ||
| This Study Will Record the Use of Budesonide / Formoterol Either as Maintenance Treatment or / or as Needed According to Standard Clinical Practice and at the Discretion of the Treating Physician.[NCT04835961] | 1,037 participants (Actual) | Observational | 2021-05-01 | Completed | |||
| Comparasion of Efficacy of Nebulized Magnesium Sulphate With Intravenous Magnesium Sulphate in Children With Acute Asthma[NCT04497766] | Phase 4 | 148 participants (Actual) | Interventional | 2019-10-01 | Completed | ||
| As Needed Budesonide/Formoterol Combination Versus Regular Budesonide/Formoterol Combination Plus as Needed Terbutaline in Mild-Moderate Persistent Asthma[NCT00849095] | Phase 3 | 860 participants (Actual) | Interventional | 2009-04-30 | Completed | ||
| The Various Effects of Gaseous Albuterol on Serum Lactate[NCT02073747] | 28 participants (Actual) | Interventional | 2015-04-30 | Completed | |||
| Study on the Effect of Precise Aerosol Inhalation Nursing Program on Effective Sputum Excretion in Elderly Patients With Lung Surgery[NCT05025215] | 200 participants (Anticipated) | Interventional | 2021-05-08 | Recruiting | |||
| Effectiveness and Costs of Albuterol Delivered by MDI With Spacer Versus Nebulizer in Children Hospitalized With Moderate and Severe Asthma Exacerbations[NCT00623688] | 11 participants (Actual) | Interventional | 2008-02-29 | Completed | |||
| Redesigning Ambulatory Care Delivery to Enhance Asthma Control in Children[NCT02409277] | 926 participants (Actual) | Interventional | 2013-08-31 | Completed | |||
| A Study of (R, R') and (S,S': R,R')- Fenoterol: Initial Clinical Evaluation for Pharmacokinetics, Pharmacodynamics, and Safety[NCT01440335] | Phase 1 | 29 participants (Actual) | Interventional | 2011-07-10 | Completed | ||
| Analysis of the Distribution of Pulmonary Ventilation After Nebulization by Heliox Associated With Positive Expiratory Pressure in Patients Asthmatics Stable.[NCT01784146] | 27 participants (Actual) | Interventional | 2009-06-30 | Completed | |||
| Effects of Herbal Lollipops on Streptococcus Mutans Levels and the Dental Caries Experience of Children With Asthma Taking beta2-adrenergic Agonist Drugs[NCT01147835] | 39 participants (Actual) | Interventional | 2009-09-23 | Terminated (stopped due to Study was stopped and not completed) | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
The ACQ developed by Juniper and colleagues (Juniper et al 1999) was used without the FEV1 and Beta 2-agonist questions. The Asthma Control Questionnaire has 5 questions that are assessed on a 7-point scale from 0 to 6 where 0 represents good control and 6 represents poor control. The overall score is the mean of the five responses. At least 4 out of the 5 questions must have been answered to provide a value. The mean of the overall score for Weeks 4 to 52 was presented here. (NCT00839800)
Timeframe: 4, 12, 24, 36 and 52 weeks after randomization
| Intervention | units on a scale (Mean) |
|---|---|
| Symbicort SMART | 1.162 |
| Symbicort+Terbutaline As Needed | 1.289 |
The mean value from the treatment period for Total Asthma Symptom Score (total score: 0 is best - no asthma symptoms; 6 is worst). (NCT00839800)
Timeframe: 52-week treatment period
| Intervention | units on a scale (Mean) |
|---|---|
| Symbicort SMART | 1.12 |
| Symbicort+Terbutaline As Needed | 1.22 |
The mean value from a 52-week treatment period. (NCT00839800)
Timeframe: 2-week run-in period (14 - 18 days before randomization - week 0) and a 52-week treatment period
| Intervention | L/min (Mean) |
|---|---|
| Symbicort SMART | 334.2 |
| Symbicort+Terbutaline As Needed | 327.8 |
The mean value for Weeks 4, 12, 24, 36 and 52 was analysed. (NCT00839800)
Timeframe: 4, 12, 24, 36 and 52 weeks after randomization
| Intervention | Liter (L) (Geometric Mean) |
|---|---|
| Symbicort SMART | 2.258 |
| Symbicort+Terbutaline As Needed | 2.222 |
The mean value from a 52-week treatment period. (NCT00839800)
Timeframe: 52-week treatment period
| Intervention | Liter/minute (L/min) (Mean) |
|---|---|
| Symbicort SMART | 331.8 |
| Symbicort+Terbutaline As Needed | 324.7 |
The mean value from the treatment period was presented here. (NCT00839800)
Timeframe: 52-week treatment period
| Intervention | Nights With Awakening(s) (Mean) |
|---|---|
| Symbicort SMART | 15.7 |
| Symbicort+Terbutaline As Needed | 17.5 |
Asthma exacerbation was defined as deterioration in asthma leading to oral GCS treatment, hospitalization, or ER treatment. Number of asthma exacerbations during 52 weeks treatment was presented here. (NCT00839800)
Timeframe: up to 52 weeks
| Intervention | Asthma exacerbations (Number) |
|---|---|
| Symbicort SMART | 259 |
| Symbicort+Terbutaline As Needed | 363 |
An as-needed-free day is defined as a night and day with no use of as-needed medication. The mean value from the treatment period was presented here. (NCT00839800)
Timeframe: 52-week treatment period
| Intervention | percentage of as-needed-free days (Mean) |
|---|---|
| Symbicort SMART | 51.4 |
| Symbicort+Terbutaline As Needed | 47.2 |
An asthma-control day was defined as a a night and day with no asthma symptoms, no awakenings due to asthma symptoms, and no as-needed medication use. The mean value from the treatment period was presented here. (NCT00839800)
Timeframe: 52-week treatment period
| Intervention | percentage of asthma-control days (Mean) |
|---|---|
| Symbicort SMART | 41.7 |
| Symbicort+Terbutaline As Needed | 37.9 |
A symptom-free day was defined as a day without daytime or night-time symptoms and without night-time awakenings due to asthma symptoms. The mean value was presented here. (NCT00839800)
Timeframe: 52-week treatment period
| Intervention | symptom-free days (Mean) |
|---|---|
| Symbicort SMART | 45.5 |
| Symbicort+Terbutaline As Needed | 41.6 |
Asthma exacerbation was defined as deterioration in asthma leading to oral glucocorticosteroid [GCS] treatment, hospitalization, or emergency room [ER] treatment. (NCT00839800)
Timeframe: week 52
| Intervention | percentage of participants (Number) |
|---|---|
| Symbicort SMART | 16 |
| Symbicort+Terbutaline As Needed | 22 |
Mild asthma exacerbation was defined as morning PEF ≥20% below baseline, daily as-needed medication use ≥2 inhalations above baseline, or a night with awakening due to asthma symptoms. The percentage of participants who had experienced mild asthma exacerbation(s) at the end of the study was presented here. (NCT00839800)
Timeframe: up to 52 weeks
| Intervention | percentage of participants (Number) |
|---|---|
| Symbicort SMART | 71 |
| Symbicort+Terbutaline As Needed | 80 |
The mean value of total daily number of inhalations from the treatment period for use of as-needed medication (daytime, night-time). (NCT00839800)
Timeframe: 52-week treatment period
| Intervention | inhalations/day (Mean) |
|---|---|
| Symbicort SMART | 1.21 |
| Symbicort+Terbutaline As Needed | 1.46 |
Severe asthma exacerbations over the randomised treatment period, negative binomial model for non-inferiority test evaluation (NCT02224157)
Timeframe: up to 52 weeks
| Intervention | exacerbations per participant year (Least Squares Mean) |
|---|---|
| Placebo Bid + Symbicort 'as Needed' (Experimental) | 0.11 |
| Pulmicort Bid + Terbutaline 'as Needed' (Active Comparator) | 0.12 |
Severe asthma exacerbations over the randomised treatment period, negative binomial model for superiority test evaluation (NCT02224157)
Timeframe: up to 52 weeks
| Intervention | exacerbations per participant year (Least Squares Mean) |
|---|---|
| Placebo Bid + Symbicort 'as Needed' (Experimental) | 0.11 |
| Pulmicort Bid + Terbutaline 'as Needed' (Active Comparator) | 0.12 |
'As-needed' use change from baseline over the randomised treatment period. Baseline was defined as the last 10 days of the run-in period. 'As needed' use was calculated as the cumulative doses of 'as-needed' medication over the randomised treatment period divided by the follow-up time (number of days - 1). ie, average number of inhalations per day. (NCT02224157)
Timeframe: Week 0 up to 52 weeks
| Intervention | Number of inhalations per day (Least Squares Mean) |
|---|---|
| Placebo Bid + Symbicort 'as Needed' (Experimental) | -0.84 |
| Pulmicort Bid + Terbutaline 'as Needed' (Active Comparator) | -0.87 |
ACQ questionnaire contains five questions on patients' symptoms, which are assessed on a 7-point scale from 0 (representing good control) to 6 (representing poor control). The score is the mean score of all questions for which responses are provided. The average change from baseline to treatment period average in ACQ-5 was derived by computing a contrast for the mean across all post-randomisation visits (week 17, 34, 52) from the MMRM (mixed model repeated measures) analysis. (NCT02224157)
Timeframe: Study weeks 0, 17, 34, 52
| Intervention | Score (Least Squares Mean) |
|---|---|
| Placebo Bid + Symbicort 'as Needed' (Experimental) | -0.35 |
| Pulmicort Bid + Terbutaline 'as Needed' (Active Comparator) | -0.46 |
AQLQ(S) consists of 32 questions in 4 domains. Each question is assessed on a 7-point scale from 1 to 7, with higher values indicating better health-related quality of life. The overall score is calculated as the mean score of all 32 items. The average change from baseline to treatment period average in AQLQ(S) overall score was derived by computing a contrast for the mean across all post-randomisation visits (week 17, 34, 52) from the MMRM (mixed model repeated measures) analysis. (NCT02224157)
Timeframe: Study weeks 0,17, 34, 52
| Intervention | AQLQ(S) overall score (Least Squares Mean) |
|---|---|
| Placebo Bid + Symbicort 'as Needed' (Experimental) | 0.335 |
| Pulmicort Bid + Terbutaline 'as Needed' (Active Comparator) | 0.431 |
The average change from baseline (baseline defined by measurement at week 0, prior to first dose of IP) to the treatment period average assessed over the entire treatment period in pre-bronchodilator FEV1 was derived by computing a contrast for the mean across the post-randomisation visits (week 17, 34, 52) from the MMRM (mixed model repeated measures) analysis. (NCT02224157)
Timeframe: Study weeks 0,17, 34, 52
| Intervention | mL (Least Squares Mean) |
|---|---|
| Placebo Bid + Symbicort 'as Needed' (Experimental) | 104.0 |
| Pulmicort Bid + Terbutaline 'as Needed' (Active Comparator) | 136.6 |
'As needed' free days (%) change from baseline during randomised treatment period. An 'as-needed' free day was defined as a day and night with no use of 'as needed' medication. Variable analysed is the percentage (%) of 'as-needed' free days during the randomised treatment period. Baseline is defined by the last 10 days of the run-in period. (NCT02224157)
Timeframe: Week 0 up to 52 weeks
| Intervention | Percentage of 'as needed' free days (Least Squares Mean) |
|---|---|
| Placebo Bid + Symbicort 'as Needed' (Experimental) | 41.01 |
| Pulmicort Bid + Terbutaline 'as Needed' (Active Comparator) | 47.86 |
A severe exacerbation is defined as a deterioration of asthma requiring any of the following: use of systemic glucocorticosteroids (GCS) for at least 3 days, inpatient hospitalization, or emergency room visit due to asthma that required systemic steroids. (NCT02224157)
Timeframe: Day 1 up to 52 weeks
| Intervention | Participants (Number) |
|---|---|
| Placebo Bid + Symbicort 'as Needed' (Experimental) | 177 |
| Pulmicort Bid + Terbutaline 'as Needed' (Active Comparator) | 184 |
The following two criteria lead to discontinuation from the IP due to asthma related events: A severe asthma exacerbation with duration for more than 3 weeks, and/or three severe asthma exacerbations during 6 months. (NCT02224157)
Timeframe: Day 1 up to 52 weeks
| Intervention | Participants (Number) |
|---|---|
| Placebo Bid + Symbicort 'as Needed' (Experimental) | 0 |
| Pulmicort Bid + Terbutaline 'as Needed' (Active Comparator) | 4 |
ICS controller use days (%) during the randomised treatment period is calculated as the cumulative days when any controller medication (containing ICS) was taken including maintenance (Pulmicort bid group) and 'as needed' medication (Symbicort 'as needed' group) and additional prescribed ICS for asthma (all treatment groups), divided by the number of days in the randomised treatment period. (NCT02224157)
Timeframe: Week 0 up to 52 weeks
| Intervention | Percentage of days (Least Squares Mean) |
|---|---|
| Placebo Bid + Symbicort 'as Needed' (Experimental) | 30.45 |
| Pulmicort Bid + Terbutaline 'as Needed' (Active Comparator) | 67.92 |
A well-controlled asthma week is defined as the fulfilment of both conditions A) and B) below: A) Two or more of the following criteria are fulfilled: - No more than 2 days with a daily asthma symptom score >1 - No more than 2 days of 'as needed' medication use, up to a maximum of 4 occasions per week (multiple occasions per day should be regarded as separate occasions) - Morning PEF ≥80% of Predicted Normal every day B) Both of the following criteria are fulfilled: - No nighttime awakenings due to asthma - No additional inhaled and/or systemic glucocorticosteroid treatment due to asthma. The binary variable well-controlled asthma week was derived for each patient and study week. In addition, for each week, the percent of patients with well-controlled asthma week was derived. It is required that the eDiary had to be completed on at least 5 days in a week to be a well-controlled asthma week. (NCT02149199)
Timeframe: Weekly, up to 52 weeks
| Intervention | Percentage (Mean) |
|---|---|
| Placebo Bid + Symbicort 'as Needed' | 34.4 |
| Placebo Bid + Terbutaline 'as Needed' | 31.1 |
| Pulmicort Bid + Terbutaline 'as Needed' | 44.4 |
Moderate or severe asthma exacerbations during the randomised treatment period. (NCT02149199)
Timeframe: up to 52 weeks
| Intervention | exacerbations per year (Least Squares Mean) |
|---|---|
| Placebo Bid + Symbicort 'as Needed' | 0.14 |
| Placebo Bid + Terbutaline 'as Needed' | 0.36 |
| Pulmicort Bid + Terbutaline 'as Needed' | 0.15 |
Severe asthma exacerbations over the randomised treatment period. (NCT02149199)
Timeframe: up to 52 weeks
| Intervention | exacerbations per year (Least Squares Mean) |
|---|---|
| Placebo Bid + Symbicort 'as Needed' | 0.07 |
| Placebo Bid + Terbutaline 'as Needed' | 0.20 |
| Pulmicort Bid + Terbutaline 'as Needed' | 0.09 |
Asthma Control Questionnaire 5-item version score change from baseline. ACQ questionnaire contains five questions on patients' symptoms, which are assessed on a 7-point scale from 0 (representing good control) to 6 (representing poor control). The score is the mean score of all questions for which responses are provided. (NCT02149199)
Timeframe: Study weeks 0,4,16,28,40,52
| Intervention | units on a scale (Least Squares Mean) |
|---|---|
| Placebo Bid + Symbicort 'as Needed' | -0.33 |
| Placebo Bid + Terbutaline 'as Needed' | -0.17 |
| Pulmicort Bid + Terbutaline 'as Needed' | -0.48 |
Asthma Quality of Life Questionnaire Standardised Version (AQLQ (S) overall score change from baseline. AQLQ(S) consists of 32 questions in 4 domains. Each question is assessed on a 7-point scale from 1 to 7, with higher values indicating better health-related quality of life. The overall score is calculated as the mean score of all 32 items. (NCT02149199)
Timeframe: Study weeks 0,16,28,40,52
| Intervention | units on a scale (Least Squares Mean) |
|---|---|
| Placebo Bid + Symbicort 'as Needed' | 0.313 |
| Placebo Bid + Terbutaline 'as Needed' | 0.186 |
| Pulmicort Bid + Terbutaline 'as Needed' | 0.415 |
Asthma symptom score (eDiary) change from baseline during the randomised treatment period. Symptom score is entered morning and evening by the patient on a 4-point scale from 0 to 3 with higher values indicating more severe symptoms. Asthma symptom score is then the sum of the day and night scores, which implies a range of scores from 0 - 6, with higher values indicating more severe symptoms. Baseline is defined as the mean of all non-missing measurements during the last 10 days of the run-in period. (NCT02149199)
Timeframe: up to 52 weeks
| Intervention | units on a scale (Least Squares Mean) |
|---|---|
| Placebo Bid + Symbicort 'as Needed' | -0.23 |
| Placebo Bid + Terbutaline 'as Needed' | -0.11 |
| Pulmicort Bid + Terbutaline 'as Needed' | -0.32 |
Evening peak expiratory flow (eDiary) change from baseline during the randomised treatment period. Baseline is defined as the mean of all non-missing evening measurements during the last 10 days of the run-in period. (NCT02149199)
Timeframe: up to 52 weeks
| Intervention | L/min (Least Squares Mean) |
|---|---|
| Placebo Bid + Symbicort 'as Needed' | -11.20 |
| Placebo Bid + Terbutaline 'as Needed' | -22.15 |
| Pulmicort Bid + Terbutaline 'as Needed' | -4.97 |
Morning peak expiratory flow (eDiary) change from baseline over the randomised treatment period. Baseline is defined as the mean of all non-missing morning measurements during the last 10 days of the run-in period. (NCT02149199)
Timeframe: up to 52 weeks
| Intervention | L/min (Least Squares Mean) |
|---|---|
| Placebo Bid + Symbicort 'as Needed' | -3.97 |
| Placebo Bid + Terbutaline 'as Needed' | -15.92 |
| Pulmicort Bid + Terbutaline 'as Needed' | 6.01 |
'As needed' inhalations change from baseline over the randomised treatment period. Baseline is defined as the last 10 days of the run-in period. 'As needed' use was calculated as the cumulative doses of 'as needed' medication over the randomised treatment period divided by the follow-up time (number of days - 1). ie, average number of inhalations per day. (NCT02149199)
Timeframe: up to 52 weeks
| Intervention | Number of inhalations per day (Mean) |
|---|---|
| Placebo Bid + Symbicort 'as Needed' | -0.95 |
| Placebo Bid + Terbutaline 'as Needed' | -0.82 |
| Pulmicort Bid + Terbutaline 'as Needed' | -1.06 |
Overall estimate of FEV1 (mL) pre-bronchodilator change from baseline. Baseline is the measurement at Visit 3 (prior to first dose of Investigational Product) from MMRM (mixed model repeated measures analysis). (NCT02149199)
Timeframe: Study weeks 0,4,16,28,40,52
| Intervention | mL (Least Squares Mean) |
|---|---|
| Placebo Bid + Symbicort 'as Needed' | 65 |
| Placebo Bid + Terbutaline 'as Needed' | 11.2 |
| Pulmicort Bid + Terbutaline 'as Needed' | 119.3 |
'As needed' free days (%) change from baseline during the randomised treatment period. An 'as needed' free day is defined as a day and night with no use of 'as needed' medication. Variable analysed is the proportion (%) of 'as needed' free days during the relevant period. Baseline refers to the last 10 days of the run-in period. (NCT02149199)
Timeframe: up to 52 weeks
| Intervention | % of days (Mean) |
|---|---|
| Placebo Bid + Symbicort 'as Needed' | 44.2 |
| Placebo Bid + Terbutaline 'as Needed' | 45.0 |
| Pulmicort Bid + Terbutaline 'as Needed' | 51.7 |
Asthma control days (%) change from baseline. An asthma control day is defined as the fulfilment of all of the following criteria; a day and night with no asthma symptoms, a night with no awakenings due to asthma symptoms and a day and night with no use of 'as needed' medication. Variable analysed is the proportion (%) of asthma control days during the randomised treatment period. Baseline refers to the last 10 days of the run-in period. (NCT02149199)
Timeframe: up to 52 weeks
| Intervention | % of days (Mean) |
|---|---|
| Placebo Bid + Symbicort 'as Needed' | 13.2 |
| Placebo Bid + Terbutaline 'as Needed' | 12.8 |
| Pulmicort Bid + Terbutaline 'as Needed' | 18.5 |
Symptom-free days (%) change from baseline during the randomised treatment period.Variable analysed is the proportion (%) of symptom-free days during the relevant period. Baseline refers to the last 10 days of the run-in period. (NCT02149199)
Timeframe: up to 52 weeks
| Intervention | % of days (Mean) |
|---|---|
| Placebo Bid + Symbicort 'as Needed' | 4.2 |
| Placebo Bid + Terbutaline 'as Needed' | 1.3 |
| Pulmicort Bid + Terbutaline 'as Needed' | 6.8 |
Night-time awakenings (%) due to asthma change from baseline. Variable analysed is the proportion (%) of nights during the relevant period with night-time awakenings. Baseline refers to the last 10 nights of the run-in period. (NCT02149199)
Timeframe: up to 52 weeks
| Intervention | % of nights (Mean) |
|---|---|
| Placebo Bid + Symbicort 'as Needed' | -7.5 |
| Placebo Bid + Terbutaline 'as Needed' | -4.6 |
| Pulmicort Bid + Terbutaline 'as Needed' | -9.8 |
"A moderate exacerbation is defined as a deterioration of asthma requiring a change in treatment, i.e. initiation of prescribed additional ICS treatment to avoid progression of the worsening of asthma to a severe exacerbation.~A severe exacerbation is defined as a deterioration of asthma requiring any of the following: use of systemic glucocorticosteroids (GCS) for at least 3 days, inpatient hospitalization, or emergency room visit due to asthma that required systemic steroids" (NCT02149199)
Timeframe: Day 1 up to 52 weeks
| Intervention | Participants (Number) |
|---|---|
| Placebo Bid + Symbicort 'as Needed' | 131 |
| Placebo Bid + Terbutaline 'as Needed' | 274 |
| Pulmicort Bid + Terbutaline 'as Needed' | 143 |
Additional steroids for asthma includes any additional inhaled and/or systemic glucocorticosteroids treatment due to asthma while in the randomised treatment period. (NCT02149199)
Timeframe: Day 1 up to 52 weeks
| Intervention | Participants (Number) |
|---|---|
| Placebo Bid + Symbicort 'as Needed' | 164 |
| Placebo Bid + Terbutaline 'as Needed' | 345 |
| Pulmicort Bid + Terbutaline 'as Needed' | 187 |
A severe exacerbation is defined as a deterioration of asthma requiring any of the following: use of systemic glucocorticosteroids (GCS) for at least 3 days, inpatient hospitalization, or emergency room visit due to asthma that required systemic steroids (NCT02149199)
Timeframe: Day 1 up to 52 weeks
| Intervention | Participants (Number) |
|---|---|
| Placebo Bid + Symbicort 'as Needed' | 71 |
| Placebo Bid + Terbutaline 'as Needed' | 152 |
| Pulmicort Bid + Terbutaline 'as Needed' | 78 |
Study specific asthma related discontinuation (NCT02149199)
Timeframe: up to 52 weeks
| Intervention | Participants (Number) |
|---|---|
| Placebo Bid + Symbicort 'as Needed' | 4 |
| Placebo Bid + Terbutaline 'as Needed' | 21 |
| Pulmicort Bid + Terbutaline 'as Needed' | 6 |
ICS controller use days (%) during the randomised treatment period is calculated as the cumulative number of days when any controller medication (containing ICS) was taken including maintenance (Pulmicort bid group) and 'as needed' medication (Symbicort 'as needed' group) and additional prescribed ICS for asthma exacerbations and/or long term poor asthma control (all treatment groups), divided by the number of days in the randomised treatment period. (NCT02149199)
Timeframe: up to 52 weeks
| Intervention | % of days (Mean) |
|---|---|
| Placebo Bid + Symbicort 'as Needed' | 30.8 |
| Placebo Bid + Terbutaline 'as Needed' | 5.6 |
| Pulmicort Bid + Terbutaline 'as Needed' | 85.6 |
A poorly-controlled asthma week is defined as a week meeting any one of the following conditions: Two or more consecutive days with awakenings due to asthma on both nights; A recorded use of 'as needed' medication for symptom relief of at least 3 occasions per day, for at least 2 consecutive days; Additional systemic GCS treatment required for severe exacerbation. If there were sufficient data within a week available to confirm the week was not poorly-controlled, the week is labelled as 'does not meet criteria for poorly-controlled'. (NCT02149199)
Timeframe: Weekly for up to 52 weeks
| Intervention | weeks (Mean) |
|---|---|
| Placebo Bid + Symbicort 'as Needed' | 7.7 |
| Placebo Bid + Terbutaline 'as Needed' | 9.7 |
| Pulmicort Bid + Terbutaline 'as Needed' | 6.7 |
We powered our study to detect a difference of 0.5 mmol/L between pre and post-treatment lactate levels, but hypothesize that the difference will be greater than 1.0 mmol/L. (NCT02073747)
Timeframe: Change in serum lactate from baseline to 1 hour
| Intervention | mmol/L (Mean) |
|---|---|
| Normal Saline Control Group | -0.15 |
| Albuterol Trial Group | 0.77 |
ED and hospital admission evaluated using data collected through Intermountain Healthcare claims data and ED visits and hospital encounters. Statistical analysis was not conducted since the numbers of ED/Hospital admissions was very small (2 and 0) in both group (during the 3 months study window). Here we used intent-to-treat analysis and included the overall 325 (rather than 318 used in analysis of other outcomes) participants. (NCT02409277)
Timeframe: 3-month period prior to the late clinics starting the e-AT
| Intervention | number of ED/Hospital admission (Number) |
|---|---|
| Early Starting Clinics | 2 |
| Late Starting Clinics | 0 |
ED and hospital admission was evaluated using data collected through Intermountain Healthcare claims data and ED visits and hospital encounters. Analyses (at the patient level) comparing the rates of ED/hospital admissions between a 1 year period following initiation of the e-AT for those in both standard and intensive e-AT groups who were enrolled early during the study period (patients with enrollment dates between January 2014 and December 2014) to rates of ED/hospital admissions for patients who started the e-AT later (patients with enrollment dates between January 2015 and December 2015), during a 1-year period prior to the late patient starting the e-AT. (NCT02409277)
Timeframe: 1 year following e-AT use for early and late starting patients
| Intervention | number of ED/Hospital admission (Mean) |
|---|---|
| Early Starting Patients | 0.10 |
| Late Starting Patients | 0.18 |
ED/hospital re-admission data were compared between prior and post 12 month period (for both intensive and standard interventions overall) when e-AT was administered. (NCT02409277)
Timeframe: 1 year
| Intervention | number of ED/hospital admission (Mean) |
|---|---|
| Prior e-AT Use | 0.22 |
| Post e-AT Use | 0.09 |
Use of oral steroid was evaluated using data collected through Intermountain Healthcare claims data and oral steroids prescribed. Statistical analysis was not conducted since the numbers of ED/Hospital admissions was very small (2 and 0) in both group (during the 3 months study window). Here we used intent-to-treat analysis and included the overall 325 (rather than 318 used in analysis of other outcomes) participants (NCT02409277)
Timeframe: 3 month period prior to the late clinics starting the e-AT
| Intervention | number of oral steroid use (Number) |
|---|---|
| Early Patients | 4 |
| Late Patients | 0 |
"Oral steroid use data was collected through Intermountain Healthcare claims data and clinics prescribing oral steroid.~Oral steroid use was evaluated using data collected through Intermountain Healthcare claims data and oral steroids prescribed. Analyses (at the patient level) comparing the rates oral steroid use between a 1 year period following initiation of the e-AT for those in both standard and intensive e-AT groups who were enrolled early during the study period (patients with enrollment dates between January 2014 and December 2014) to rates of oral steroid use for patients who started the e-AT later (patients with enrollment dates between January 2015 and December 2015), during a 1-year period prior to the late patient starting the e-AT." (NCT02409277)
Timeframe: 1 year
| Intervention | number of oral steroid use (Mean) |
|---|---|
| Early Starting Patients | 0.53 |
| Late Starting Patients | 0.53 |
Use of oral steroid was evaluated using data collected through Intermountain Healthcare claims data and oral steroids prescribed. Comparison was made between prior and post e-AT (both interventions) overall. (NCT02409277)
Timeframe: 1 year
| Intervention | number of oral steroid use (Mean) |
|---|---|
| Prior e-AT Use | 0.74 |
| Post e-AT Use | 0.51 |
Asthma control information was collected weekly through the e-AT for 1 year. Asthma control was measured using the Asthma Control Test (ACT), which had a score ranging from 5 to 25, with 5 being poor control and 25 being optimal control. The analysis compared the mean change in scores from baseline to quarters 1, 2, 3, and 4. (NCT02409277)
Timeframe: Average baseline ACT scores compared to average ACT scores at quarter 1, 2, 3 and 4, and between Standard vs. Intensive
| Intervention | mean score (points) change (Mean) | |||
|---|---|---|---|---|
| Qtr 1 vs baseline | Qtr 2 vs baseline | Qtr 3 vs baseline | Qtr 4 vs baseline | |
| Intensive e-AT Intervention | 1.78 | 2.18 | 2.18 | 3.30 |
| Standard e-AT Intervention | 2.55 | 3.09 | 3.26 | 3.33 |
"Asthma control information was collected through the e-AT, comparing change of asthma control from baseline to quarter 1, quarter 2, quarter 3 and quarter 4.~Asthma control was measured using the Asthma Control Test (ACT), which scale ranged from 5-25, with 5=poorly controlled and 25=well controlled.~Each patient submitted an ACT score weekly for 12 months." (NCT02409277)
Timeframe: baseline ACT scores were compared to quarters 1, 2, 3, 4.
| Intervention | Score (points) ranging from 5-25 (Mean) | ||||
|---|---|---|---|---|---|
| Baseline | Quarter 1 | Quarter 2 | Quarter 3 | Quarter 4 | |
| All e-AT Users | 18.85 | 22.28 | 22.82 | 22.81 | 22.97 |
Number of child interrupted/missed school days were collected longitudinally (information includes mean at baseline, 3, 6, and 12 months in the study). (NCT02409277)
Timeframe: 1 year
| Intervention | Number of days (interrupted or missed) (Mean) | |||
|---|---|---|---|---|
| Baseline | 3 Months Follow-up | 6 Months Follow-up | 12 Months Follow-up | |
| All e-AT Users | 1.91 | 0.80 | 0.52 | 0.79 |
"Number of child interrupted/missed school days were collected longitudinally at the same time as collecting the QOL scores: baseline, 3, 6, and 12 months in the study.~Number of child interrupted/missed school days during the 3 months prior to baseline, 3, 6, and 12 months follow-up surveys were counted." (NCT02409277)
Timeframe: Interrupted/missed school days were collected at baseline, 3, 6, and 12 month follow-ups
| Intervention | Number of interrupted/missed school days (Number) | |||
|---|---|---|---|---|
| Baseline | 3 Months Follow-up | 6 Months Follow-up | 12 Months Follow-up | |
| Intensive e-AT Intervention | 129 | 60 | 30 | 37 |
| Standard e-AT Intervention | 435 | 114 | 87 | 129 |
Non randomized comparison of ED and hospital admissions between e-AT interventions (both intensive and standard) compared usual care (matched control patients drawn from non-participating clinics) in the prior vs. post e-AT intervention time periods. (NCT02409277)
Timeframe: 1 year
| Intervention | Rate per 1000-days (Mean) | |
|---|---|---|
| Prior | Post | |
| e-AT Intervention | 0.59 | 0.24 |
| Usual Care (Non-randomized Cohort) | 0.23 | 0.24 |
"ED and hospital admissions were evaluated using data collected through Intermountain Healthcare claims data and ED visits and hospital encounters.~We evaluated number ED and hospital admissions 12 months prior to intervention and 12 months post intervention" (NCT02409277)
Timeframe: Change in 1 year ED/hospital admission between 12-month prior and 12 month post e-AT use
| Intervention | Number of ED/hospital admissions (Number) | |
|---|---|---|
| Prior | Post | |
| Intensive e-AT Intervention | 18 | 8 |
| Standard e-AT Intervention | 53 | 21 |
Non randomized comparison of use of oral steroid between e-AT interventions (both intensive and standard) compared usual care (matched control patients drawn from non-participating clinics) in the prior vs. post e-AT intervention time periods. (NCT02409277)
Timeframe: 1 year
| Intervention | Rate per 1000-days (Mean) | |
|---|---|---|
| Prior | Post | |
| e-AT Intervention | 2.02 | 1.41 |
| Usual Care (Non-randomized Cohort) | 1.87 | 1.99 |
Number of parent interrupted/missed work days were collected longitudinally at the same time as collecting the QOL scores: Information includes mean at baseline, 3, 6, and 12 months in the study. (NCT02409277)
Timeframe: 1 year
| Intervention | Number of days (interrupted or missed) (Mean) | |||
|---|---|---|---|---|
| Baseline | 3 Months Follow-up | 6 Months Follow-Up | 12 Months Follow-up | |
| All e-AT Users | 0.72 | 0.27 | 0.25 | 0.20 |
"Number of parent interrupted/missed work days were collected longitudinally at the same time as collecting the QOL scores: baseline, 3, 6, and 12 months in the study.~Number of parent interrupted/missed work days during the 3 months prior to baseline, 3, 6, and 12 months follow-up surveys were counted." (NCT02409277)
Timeframe: Interrupted/missed work days were measured baseline 3, 6, and 12 months
| Intervention | Number of interrupted/missed work days (Number) | |||
|---|---|---|---|---|
| Baseline | 3 Months Follow-up | 6 Months Follow-up | 12 Months Follow-up | |
| Intensive e-AT Intervention | 56 | 14 | 15 | 18 |
| Standard e-AT Intervention | 176 | 44 | 42 | 23 |
"Parent satisfaction data was collected using a modified version of patient satisfaction survey developed and validated by Varni et al. at baseline and at 12 months in the study.~The scale ranged from 1-5, with 1=Very Dissatisfied and 5=Very Satisfied." (NCT02409277)
Timeframe: Satisfaction at 1 year following e-AT use was compared to baseline satisfaction scores
| Intervention | units (points) on a scale (from 1-5) (Mean) | |
|---|---|---|
| Baseline | 12 months Follow-up | |
| All e-AT Users | 4.66 | 4.46 |
"Parent satisfaction data was collected at baseline and at 12 months in the study.~The scale ranges from 1-5, with 1 being Very Dissatisfied and 5 Very Satisfied." (NCT02409277)
Timeframe: Changes in satisfaction was compared between 12 month follow-up and baseline satisfaction across Standard and Intensive interventions
| Intervention | units (points) on a scale (from 1-5) (Mean) | |
|---|---|---|
| Baseline | 12 months Follow-up | |
| Intensive e-AT Intervention | 4.63 | 4.54 |
| Standard e-AT Intervention | 4.63 | 4.38 |
"Patient QOL and missed school days was collected longitudinally through surveys of the study population defined above. The QOL questionnaire included the Integrated Therapeutics Group Child Asthma Short Form (ITG-CASF) and was used at baseline (at first assessment), 3, 6, and 12 months in the study.~Items within QOL scales are summed and linearly transformed from 0 to 100, with higher scores indicating better functioning." (NCT02409277)
Timeframe: Quality of Life assessed at baseline, then compared to 3 months, 6 months, and 12 months after intervention.
| Intervention | Units on a scale (Mean) | ||
|---|---|---|---|
| 3 Months Follow-up vs Baseline | 6 Months Follow-up compared vs Baseline | 12 Months Follow-up vs Baseline | |
| Intensive e-AT Intervention | 7.64 | 5.78 | 9.29 |
| Standard e-AT Intervention | 8.55 | 8.37 | 9.39 |
Patient QOL and missed school days was collected longitudinally through surveys of the study population defined above. The QOL questionnaire included the Integrated Therapeutics Group Child Asthma Short Form - ITG-CASF and was used at baseline (at first assessment), 3, 6, and 12 months in the study. Items within scales are summed and linearly transformed from 0 to 100, with higher scores indicating better functioning. (NCT02409277)
Timeframe: Average Baseline QOL was compared to QOL scores at 3, 6 and 12 month follow-up QOL
| Intervention | units (points) on a scale, range 0-100 (Mean) | |||
|---|---|---|---|---|
| Baseline | 3 Months | 6 Months | 12 Months | |
| All e-AT Users | 79.07 | 90.98 | 90.04 | 90.64 |
48 reviews available for terbutaline and Asthma
| Article | Year |
|---|---|
Clinical pharmacokinetics of terbutaline in humans: a systematic review.
Topics: Administration, Intravenous; Asthma; Female; Humans; Kinetics; Pregnancy; Terbutaline; Theophylline | 2023 |
Safety of SABA Monotherapy in Asthma Management: a Systematic Review and Meta-analysis.
Topics: Administration, Inhalation; Adolescent; Adrenal Cortex Hormones; Adult; Anti-Asthmatic Agents; Asthm | 2023 |
Combination fixed-dose beta agonist and steroid inhaler as required for adults or children with mild asthma.
Topics: Adolescent; Adrenal Cortex Hormones; Adrenergic beta-2 Receptor Agonists; Adult; Anti-Asthmatic Agen | 2021 |
[Clinical application of transdermal beta-2 agonists for the wheezing diseases in childhood].
Topics: Adrenergic beta-2 Receptor Agonists; Asthma; Bronchitis; Bronchodilator Agents; Child; Child, Presch | 2013 |
Combination formoterol and budesonide as maintenance and reliever therapy versus current best practice (including inhaled steroid maintenance), for chronic asthma in adults and children.
Topics: Administration, Inhalation; Adolescent; Adrenal Cortex Hormones; Adult; Anti-Asthmatic Agents; Asthm | 2013 |
Combination formoterol and inhaled steroid versus beta2-agonist as relief medication for chronic asthma in adults and children.
Topics: Administration, Inhalation; Adolescent; Adult; Anti-Asthmatic Agents; Asthma; Bronchial Diseases; Br | 2009 |
Combination formoterol and budesonide as maintenance and reliever therapy versus inhaled steroid maintenance for chronic asthma in adults and children.
Topics: Administration, Inhalation; Adrenal Cortex Hormones; Adult; Anti-Asthmatic Agents; Asthma; Bronchodi | 2009 |
Use of dry powder inhalers in acute exacerbations of asthma and COPD.
Topics: Adrenergic beta-Agonists; Albuterol; Asthma; Bronchodilator Agents; Disease Progression; Ethanolamin | 2009 |
Management of severe asthma in children.
Topics: Administration, Inhalation; Adrenal Cortex Hormones; Allergens; Anti-Asthmatic Agents; Asthma; Azath | 2010 |
Formoterol versus short-acting beta-agonists as relief medication for adults and children with asthma.
Topics: Adult; Age Factors; Albuterol; Asthma; Bronchodilator Agents; Budesonide; Child; Cromolyn Sodium; Et | 2010 |
Continuous infusions of terbutaline in asthma - a review.
Topics: Adrenergic beta-Agonists; Asthma; Humans; Infusions, Subcutaneous; Peak Expiratory Flow Rate; Terbut | 2011 |
Transdermal tulobuterol patch, a long-actingβ(2)-agonist.
Topics: Adrenergic beta-Agonists; Asthma; Bronchodilator Agents; Drug Approval; Evidence-Based Medicine; Hum | 2012 |
Regular treatment with formoterol for chronic asthma: serious adverse events.
Topics: Adrenergic beta-Agonists; Adult; Age Factors; Albuterol; Asthma; Bronchodilator Agents; Child; Chron | 2012 |
Addition of intravenous beta(2)-agonists to inhaled beta(2)-agonists for acute asthma.
Topics: Acetamides; Acute Disease; Administration, Inhalation; Administration, Intravenous; Adrenal Cortex H | 2012 |
From adrenaline to formoterol: advances in beta-agonist therapy in the treatment of asthma.
Topics: Administration, Inhalation; Adrenergic beta-Agonists; Albuterol; Asthma; Bronchodilator Agents; Etha | 2002 |
The use of inhaled formoterol in the treatment of asthma.
Topics: Administration, Inhalation; Adolescent; Adrenergic beta-2 Receptor Agonists; Adrenergic beta-Agonist | 2006 |
Managing bronchospasm with short-acting beta(2)-agonists.
Topics: Acute Disease; Adrenergic beta-2 Receptor Agonists; Adrenergic beta-Agonists; Adult; Albuterol; Asth | 2006 |
Adrenergic drugs.
Topics: Adrenergic beta-Agonists; Aerosols; Albuterol; Asthma; Catecholamines; Chemical Phenomena; Chemistry | 1983 |
Clinical pharmacology of adrenergic drugs.
Topics: Adrenergic beta-Agonists; Aerosols; Asthma; Biological Availability; Bronchodilator Agents; Catechol | 1984 |
Adrenergic agents in acute asthma: valuable new alternatives.
Topics: Acute Disease; Aerosols; Albuterol; Asthma; Bronchi; Bronchodilator Agents; Epinephrine; Humans; Iso | 1983 |
Bronchial asthma in adults: presentation to the emergency department. Part II: Sympathomimetics, respiratory failure, recommendations for initial treatment, indications for admission, and summary.
Topics: Adrenal Cortex Hormones; Albuterol; Aminophylline; Asthma; Emergencies; Epinephrine; Humans; Hydroge | 1983 |
Asthma in childhood.
Topics: Adolescent; Asthma; Beclomethasone; Behavior Therapy; Child; Child, Preschool; Cromolyn Sodium; Epin | 1983 |
Response: asthma in childhood.
Topics: Administration, Oral; Adrenal Cortex Hormones; Aerosols; Albuterol; Asthma; Bronchodilator Agents; C | 1983 |
Clinical pharmacokinetics of bambuterol.
Topics: Animals; Asthma; Bronchodilator Agents; Humans; Prodrugs; Terbutaline; Tissue Distribution | 1996 |
[The brittle asthmatic and the morning dipper].
Topics: Adrenergic beta-Agonists; Anti-Inflammatory Agents; Asthma; Bronchodilator Agents; Chromones; Circad | 1996 |
Emergency treatment of asthma.
Topics: Acute Disease; Administration, Inhalation; Adrenal Cortex Hormones; Adrenergic beta-Agonists; Airway | 1996 |
Long-acting inhaled beta 2-agonists and the loss of "bronchoprotective" efficacy.
Topics: Adrenergic beta-Agonists; Asthma; Bronchoconstrictor Agents; Bronchodilator Agents; Ethanolamines; F | 1998 |
Inhaled beta2-agonists and airway responses to allergen.
Topics: Adenosine Monophosphate; Administration, Inhalation; Adrenergic beta-Agonists; Albuterol; Allergens; | 1998 |
Difficult asthma: beyond the guidelines.
Topics: Asthma; Budesonide; Child; Chronic Disease; Cyclosporine; Drug Administration Routes; Glucocorticoid | 1999 |
Review of therapeutically equivalent alternatives to short acting beta(2) adrenoceptor agonists delivered via chlorofluorocarbon-containing inhalers.
Topics: Adrenergic beta-Agonists; Albuterol; Asthma; Chlorofluorocarbons; Clinical Trials as Topic; Drug Del | 1999 |
Pharmacological similarities and differences between beta2-agonists.
Topics: Adrenergic beta-Agonists; Albuterol; Animals; Asthma; Blood Glucose; Blood Pressure; Bronchodilator | 2001 |
[Japanese guideline for the diagnosis and management of bronchial asthma (1998)--its results and reversion].
Topics: Administration, Cutaneous; Administration, Inhalation; Aminophylline; Androstadienes; Asthma; Eviden | 2001 |
[Long-acting beta 2-stimulants].
Topics: Administration, Cutaneous; Administration, Inhalation; Adrenergic beta-2 Receptor Agonists; Adrenerg | 2001 |
[Development of transdermal formulation of tulobuterol for the treatment of bronchial asthma].
Topics: Administration, Cutaneous; Adrenergic beta-Agonists; Asthma; Chronotherapy; Clinical Trials as Topic | 2002 |
Newer medications to aid treatment of asthma.
Topics: Adrenal Cortex Hormones; Adrenergic alpha-Agonists; Adrenergic beta-Agonists; Aminophylline; Asthma; | 1977 |
Rimiterol: a review of its pharmacological properties and therapeutic efficacy in asthma.
Topics: Absorption; Administration, Oral; Aerosols; Albuterol; Animals; Asthma; Bronchodilator Agents; Catec | 1977 |
Long-term treatment with beta2-adrenostimulants in asthma. Side effects, selectivity, tolerance, and routes of administration.
Topics: Administration, Oral; Adrenergic beta-Agonists; Aerosols; Albuterol; Arrhythmias, Cardiac; Asthma; E | 1977 |
[Pulmonary function tests with the bronchodilator Terbutaline].
Topics: Administration, Oral; Adult; Aged; Albuterol; Asthma; Atropine; Clenbuterol; Epinephrine; Female; Fe | 1979 |
New drug therapy for asthma.
Topics: Asthma; Atropine; Beclomethasone; Cromolyn Sodium; Humans; Isoproterenol; Metaproterenol; Receptors, | 1978 |
Review of sympathomimetic bronchodilators.
Topics: Asthma; Bronchi; Bronchodilator Agents; Ephedrine; Epinephrine; Humans; Isoetharine; Isoproterenol; | 1979 |
Beta 2 agonist therapy: oral versus inhaled delivery.
Topics: Administration, Inhalation; Administration, Oral; Adrenergic beta-Agonists; Albuterol; Asthma; Human | 1992 |
[Nocturnal bronchial asthma: mechanisms of development and prevention of attacks].
Topics: Adrenergic beta-Agonists; Asthma; Bronchodilator Agents; Circadian Rhythm; Humans; Respiratory Thera | 1991 |
Tulobuterol in the management of obstructive airways disease in adults.
Topics: Adrenal Cortex Hormones; Adrenergic beta-Agonists; Adult; Aged; Asthma; Bronchodilator Agents; Femal | 1985 |
Chronobiology and asthma. II. Body-time-dependent differences in the kinetics and effects of bronchodilator medications.
Topics: Adult; Airway Resistance; Asthma; Bronchodilator Agents; Chronobiology Phenomena; Delayed-Action Pre | 1987 |
Assessing severity of adult asthma and need for hospitalization.
Topics: Acidosis; Adult; Age Factors; Aged; Airway Obstruction; Asthma; Epinephrine; Female; Forced Expirato | 1985 |
Clinical aspects of mucus and mucous plugging in asthma.
Topics: Acetylcysteine; Asthma; Biological Transport; Bronchi; Cilia; Expectorants; Humans; Mucus; Pulmonary | 1985 |
[Treatment of bronchial asthma].
Topics: Adrenergic alpha-Agonists; Adrenergic beta-Agonists; Albuterol; Aminophylline; Asthma; Bronchitis; C | 1974 |
Asthma: current concepts.
Topics: Adolescent; Albuterol; Asthma; Beclomethasone; Bronchodilator Agents; Carboxylic Acids; Child; Child | 1974 |
439 trials available for terbutaline and Asthma
| Article | Year |
|---|---|
Budesonide-formoterol reliever therapy versus maintenance budesonide plus terbutaline reliever therapy in adults with mild to moderate asthma (PRACTICAL): a 52-week, open-label, multicentre, superiority, randomised controlled trial.
Topics: Adolescent; Adult; Aged; Anti-Asthmatic Agents; Asthma; Bronchodilator Agents; Budesonide; Budesonid | 2019 |
Response to bronchodilator and clinical, pathophysiological features in patients with nonasthmatic eosinophilic bronchitis.
Topics: Administration, Oral; Adult; Airway Remodeling; Asthma; Bronchial Hyperreactivity; Bronchitis; Bronc | 2020 |
Determinants of response to bronchodilator in patients with cough variant asthma- A randomized, single-blinded, placebo-controlled study.
Topics: Adrenergic beta-2 Receptor Agonists; Adult; Aged; Asthma; Bronchial Hyperreactivity; Bronchial Provo | 2020 |
Detecting asthma exacerbations using daily home monitoring and machine learning.
Topics: Asthma; Bronchodilator Agents; Budesonide; Disease Progression; Drug Combinations; Female; Formotero | 2021 |
What matters most to patients when choosing treatment for mild-moderate asthma? Results from a discrete choice experiment.
Topics: Adult; Asthma; Bronchodilator Agents; Budesonide, Formoterol Fumarate Drug Combination; Decision Mak | 2020 |
Combination budesonide/formoterol inhaler as sole reliever therapy in Māori and Pacific people with mild and moderate asthma.
Topics: Administration, Inhalation; Adult; Anti-Asthmatic Agents; Asthma; Bronchodilator Agents; Budesonide; | 2020 |
Safety of As-Needed Budesonide-Formoterol in Mild Asthma: Data from the Two Phase III SYGMA Studies.
Topics: Administration, Inhalation; Asthma; Bronchodilator Agents; Budesonide; Drug Combinations; Ethanolami | 2021 |
Safety of As-Needed Budesonide-Formoterol in Mild Asthma: Data from the Two Phase III SYGMA Studies.
Topics: Administration, Inhalation; Asthma; Bronchodilator Agents; Budesonide; Drug Combinations; Ethanolami | 2021 |
Safety of As-Needed Budesonide-Formoterol in Mild Asthma: Data from the Two Phase III SYGMA Studies.
Topics: Administration, Inhalation; Asthma; Bronchodilator Agents; Budesonide; Drug Combinations; Ethanolami | 2021 |
Safety of As-Needed Budesonide-Formoterol in Mild Asthma: Data from the Two Phase III SYGMA Studies.
Topics: Administration, Inhalation; Asthma; Bronchodilator Agents; Budesonide; Drug Combinations; Ethanolami | 2021 |
Efficacy and Safety of As-Needed Budesonide-Formoterol in Adolescents with Mild Asthma.
Topics: Administration, Inhalation; Adolescent; Asthma; Bronchodilator Agents; Budesonide; Budesonide, Formo | 2021 |
Efficacy of budesonide/formoterol maintenance and reliever therapy compared with higher-dose budesonide as step-up from low-dose inhaled corticosteroid treatment.
Topics: Administration, Inhalation; Adolescent; Adrenal Cortex Hormones; Adrenergic beta-2 Receptor Agonists | 2017 |
As-Needed Budesonide-Formoterol versus Maintenance Budesonide in Mild Asthma.
Topics: Administration, Inhalation; Adolescent; Adult; Aged; Aged, 80 and over; Asthma; Bronchodilator Agent | 2018 |
As-Needed Budesonide-Formoterol versus Maintenance Budesonide in Mild Asthma.
Topics: Administration, Inhalation; Adolescent; Adult; Aged; Aged, 80 and over; Asthma; Bronchodilator Agent | 2018 |
As-Needed Budesonide-Formoterol versus Maintenance Budesonide in Mild Asthma.
Topics: Administration, Inhalation; Adolescent; Adult; Aged; Aged, 80 and over; Asthma; Bronchodilator Agent | 2018 |
As-Needed Budesonide-Formoterol versus Maintenance Budesonide in Mild Asthma.
Topics: Administration, Inhalation; Adolescent; Adult; Aged; Aged, 80 and over; Asthma; Bronchodilator Agent | 2018 |
As-Needed Budesonide-Formoterol versus Maintenance Budesonide in Mild Asthma.
Topics: Administration, Inhalation; Adolescent; Adult; Aged; Aged, 80 and over; Asthma; Bronchodilator Agent | 2018 |
As-Needed Budesonide-Formoterol versus Maintenance Budesonide in Mild Asthma.
Topics: Administration, Inhalation; Adolescent; Adult; Aged; Aged, 80 and over; Asthma; Bronchodilator Agent | 2018 |
As-Needed Budesonide-Formoterol versus Maintenance Budesonide in Mild Asthma.
Topics: Administration, Inhalation; Adolescent; Adult; Aged; Aged, 80 and over; Asthma; Bronchodilator Agent | 2018 |
As-Needed Budesonide-Formoterol versus Maintenance Budesonide in Mild Asthma.
Topics: Administration, Inhalation; Adolescent; Adult; Aged; Aged, 80 and over; Asthma; Bronchodilator Agent | 2018 |
As-Needed Budesonide-Formoterol versus Maintenance Budesonide in Mild Asthma.
Topics: Administration, Inhalation; Adolescent; Adult; Aged; Aged, 80 and over; Asthma; Bronchodilator Agent | 2018 |
Inhaled Combined Budesonide-Formoterol as Needed in Mild Asthma.
Topics: Administration, Inhalation; Adolescent; Adult; Aged; Asthma; Bronchodilator Agents; Budesonide; Chil | 2018 |
Inhaled Combined Budesonide-Formoterol as Needed in Mild Asthma.
Topics: Administration, Inhalation; Adolescent; Adult; Aged; Asthma; Bronchodilator Agents; Budesonide; Chil | 2018 |
Inhaled Combined Budesonide-Formoterol as Needed in Mild Asthma.
Topics: Administration, Inhalation; Adolescent; Adult; Aged; Asthma; Bronchodilator Agents; Budesonide; Chil | 2018 |
Inhaled Combined Budesonide-Formoterol as Needed in Mild Asthma.
Topics: Administration, Inhalation; Adolescent; Adult; Aged; Asthma; Bronchodilator Agents; Budesonide; Chil | 2018 |
Inhaled Combined Budesonide-Formoterol as Needed in Mild Asthma.
Topics: Administration, Inhalation; Adolescent; Adult; Aged; Asthma; Bronchodilator Agents; Budesonide; Chil | 2018 |
Inhaled Combined Budesonide-Formoterol as Needed in Mild Asthma.
Topics: Administration, Inhalation; Adolescent; Adult; Aged; Asthma; Bronchodilator Agents; Budesonide; Chil | 2018 |
Inhaled Combined Budesonide-Formoterol as Needed in Mild Asthma.
Topics: Administration, Inhalation; Adolescent; Adult; Aged; Asthma; Bronchodilator Agents; Budesonide; Chil | 2018 |
Inhaled Combined Budesonide-Formoterol as Needed in Mild Asthma.
Topics: Administration, Inhalation; Adolescent; Adult; Aged; Asthma; Bronchodilator Agents; Budesonide; Chil | 2018 |
Inhaled Combined Budesonide-Formoterol as Needed in Mild Asthma.
Topics: Administration, Inhalation; Adolescent; Adult; Aged; Asthma; Bronchodilator Agents; Budesonide; Chil | 2018 |
Topics: Administration, Inhalation; Adult; Asthma; Budesonide; Budesonide, Formoterol Fumarate Drug Combinat | 2018 |
Topics: Adolescent; Adult; Asthma; Budesonide; Double-Blind Method; Drug Administration Schedule; Female; Fo | 2018 |
The Effects of Inhaled Terbutaline on 3-km Running Time-Trial Performance.
Topics: Administration, Inhalation; Adult; Asthma; Athletic Performance; Female; Forced Expiratory Volume; H | 2019 |
[Efficacy and safety of tulobuterol patch versus oral salbutamol sulfate in children with mild or moderate acute attack of bronchial asthma: a comparative study].
Topics: Acute Disease; Administration, Oral; Adrenergic beta-2 Receptor Agonists; Albuterol; Asthma; Female; | 2013 |
Randomised comparison of intravenous magnesium sulphate, terbutaline and aminophylline for children with acute severe asthma.
Topics: Acute Disease; Administration, Intravenous; Aminophylline; Analgesics; Asthma; Bronchodilator Agents | 2014 |
Budesonide/formoterol maintenance and reliever therapy in asthma control: acute, dose-related effects and real-life effectiveness.
Topics: Administration, Inhalation; Adult; Asthma; Breath Tests; Bronchodilator Agents; Budesonide, Formoter | 2015 |
Regular versus as-needed budesonide and formoterol combination treatment for moderate asthma: a non-inferiority, randomised, double-blind clinical trial.
Topics: Administration, Inhalation; Adolescent; Adult; Aged; Anti-Asthmatic Agents; Asthma; Bronchodilator A | 2015 |
A 12-week, randomized, parallel-group, proof-of-concept study of tulobuterol patch and salmeterol inhaler as add-on therapy in adult-onset mild-to-moderate asthma.
Topics: Adult; Aged; Asthma; Bronchodilator Agents; Drug Therapy, Combination; Female; Follow-Up Studies; Hu | 2017 |
Budesonide/formoterol as maintenance and reliever treatment compared to fixed dose combination strategies - a Canadian economic evaluation.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Albuterol; Androstadienes; Asthma; Bronchodilator Agents | 2008 |
A real-life cost-effectiveness evaluation of budesonide/formoterol maintenance and reliever therapy in asthma.
Topics: Administration, Inhalation; Adolescent; Adult; Asthma; Bronchodilator Agents; Budesonide; Child; Cos | 2008 |
Effectiveness of high repeated doses of inhaled budesonide or fluticasone in controlling acute asthma exacerbations in young children.
Topics: Acute Disease; Administration, Inhalation; Androstadienes; Asthma; Bronchodilator Agents; Budesonide | 2008 |
Effect of ligustrazine injection on levels of interleukin-4 and interferon-gamma in patients with bronchial asthma.
Topics: Adrenergic beta-Agonists; Aged; Aged, 80 and over; Asthma; Case-Control Studies; Female; Humans; Inj | 2008 |
Effects of the addition of Beta2-agonist tulobuterol patches to inhaled corticosteroid in patients with asthma.
Topics: Administration, Inhalation; Adrenal Cortex Hormones; Adrenergic beta-Agonists; Adult; Aged; Asthma; | 2009 |
A randomized, comparative study of formoterol and terbutaline dry powder inhalers in the treatment of mild to moderate asthma exacerbations in the pediatric acute care setting.
Topics: Administration, Inhalation; Asthma; Child; Disease Progression; Emergency Medical Services; Ethanola | 2009 |
Bromotyrosines in sputum proteins and treatment effects of terbutaline and budesonide in asthma.
Topics: Adolescent; Adrenergic beta-Agonists; Adult; Asthma; Bronchodilator Agents; Budesonide; Cross-Over S | 2009 |
Thirteen-year follow-up of early intervention with an inhaled corticosteroid in patients with asthma.
Topics: Administration, Inhalation; Anti-Asthmatic Agents; Asthma; Bronchodilator Agents; Budesonide; Double | 2009 |
The effect of terbutaline on the absorption of pulmonary administered insulin in subjects with asthma.
Topics: Absorption; Administration, Inhalation; Adolescent; Adult; Anti-Asthmatic Agents; Asthma; Bronchocon | 2010 |
Acute supra-therapeutic oral terbutaline administration has no ergogenic effect in non-asthmatic athletes.
Topics: Administration, Oral; Adrenergic beta-2 Receptor Agonists; Adult; Asthma; Athletic Performance; Bron | 2013 |
[Clinical effects of budesonide/formoterol combination drug in elder patients with asthma compared with budesonide plus tulobuterol patch combination treatment].
Topics: Aged; Aged, 80 and over; Asthma; Biomarkers; Breath Tests; Bronchodilator Agents; Budesonide; Drug T | 2012 |
Effects of transdermal tulobuterol in pediatric asthma patients on long-term leukotriene receptor antagonist therapy: results of a randomized, open-label, multicenter clinical trial in Japanese children aged 4-12 years.
Topics: Administration, Cutaneous; Adrenergic beta-Agonists; Asthma; Child; Child, Preschool; Female; Humans | 2013 |
Budesonide/formoterol maintenance and reliever therapy via Turbuhaler versus fixed-dose budesonide/formoterol plus terbutaline in patients with asthma: phase III study results.
Topics: Administration, Inhalation; Adrenal Cortex Hormones; Adult; Asthma; Bronchodilator Agents; Budesonid | 2013 |
Safety of formoterol by Turbuhaler as reliever medication compared with terbutaline in moderate asthma.
Topics: Administration, Inhalation; Adrenal Cortex Hormones; Adult; Asthma; Dose-Response Relationship, Drug | 2002 |
Eosinophils and eosinophilic cationic protein in induced sputum and blood: effects of budesonide and terbutaline treatment.
Topics: Administration, Topical; Adult; Anti-Inflammatory Agents; Asthma; Blood Proteins; Bronchodilator Age | 2002 |
Effects of terbutaline in combination with mannitol on mucociliary clearance.
Topics: Administration, Inhalation; Adrenergic beta-Agonists; Adult; Asthma; Diuretics, Osmotic; Drug Therap | 2002 |
Comparative efficacy of terbutaline sulphate delivered by Turbuhaler dry powder inhaler or pressurised metered dose inhaler with Nebuhaler spacer in children during an acute asthmatic episode.
Topics: Acute Disease; Administration, Inhalation; Adolescent; Adrenergic beta-Agonists; Asthma; Bronchodila | 2003 |
Creatininuria in asthmatic children treated with a combination of glucocorticoid and beta-agonist.
Topics: Administration, Inhalation; Adrenergic beta-Agonists; Albuterol; Anti-Asthmatic Agents; Asthma; Becl | 2003 |
[A multi-centered clinical study an domestic intravenous Turbutalin sulfate in the treatment of asthma and chronic asthmatic bronchitis].
Topics: Adolescent; Adrenergic beta-Agonists; Adult; Aged; Asthma; Bronchitis, Chronic; Female; Humans; Infu | 2001 |
The bronchodilatory effects of loratadine, terbutaline, and both together versus placebo in childhood asthma.
Topics: Administration, Inhalation; Administration, Oral; Adolescent; Asthma; Bronchodilator Agents; Child; | 2003 |
[Clinical evaluation of tulobuterol patch in patients with mild or moderate persistent bronchial asthma-effects of long-term treatment on airway inflammation and hypersensitivity].
Topics: Administration, Cutaneous; Administration, Inhalation; Adrenergic beta-Agonists; Aged; Androstadiene | 2004 |
Clinical evaluation of a transdermal therapeutic system of the beta2-agonist tulobuterol in patients with mild or moderate persistent bronchial asthma.
Topics: Administration, Cutaneous; Adult; Anti-Asthmatic Agents; Asthma; Blood Proteins; Bronchial Hyperreac | 2004 |
Comparison of nebulized epinephrine and terbutaline in patients with acute severe asthma: a controlled trial.
Topics: Acute Disease; Adolescent; Adrenergic beta-Agonists; Adult; Aerosols; Asthma; Bronchodilator Agents; | 2004 |
Cumulative high doses of inhaled formoterol have less systemic effects in asthmatic children 6-11 years-old than cumulative high doses of inhaled terbutaline.
Topics: Administration, Inhalation; Asthma; Blood Pressure; Bronchodilator Agents; Child; Cross-Over Studies | 2004 |
Comparison of terbutaline and salbutamol inhalation in children with mild or moderate acute exacerbation of asthma.
Topics: Administration, Inhalation; Adolescent; Albuterol; Asthma; Child; Confidence Intervals; Dose-Respons | 2004 |
Formoterol used as needed in patients with intermittent or mild persistent asthma.
Topics: Administration, Inhalation; Adolescent; Adrenergic beta-Agonists; Adult; Aged; Aged, 80 and over; As | 2005 |
Mucociliary clearance in patients with chronic asthma: effects of beta agonists.
Topics: Administration, Inhalation; Adolescent; Adrenergic beta-Agonists; Adult; Aged; Asthma; Chronic Disea | 2005 |
[Metered-dose inhaler with spacer vs nebulization for severe and potentially severe acute asthma treatment in the pediatric emergency department].
Topics: Acute Disease; Adolescent; Adrenal Cortex Hormones; Albuterol; Anti-Asthmatic Agents; Asthma; Bronch | 2006 |
Comparison of the effects of nebulized terbutaline with or without intravenous betamethasone on exhaled nitric oxide in children with acute asthma attack.
Topics: Acute Disease; Adolescent; Anti-Asthmatic Agents; Asthma; Betamethasone; Breath Tests; Bronchodilato | 2006 |
Improvement of otitis media with effusion after treatment of asthma with leukotriene antagonists in children with co-existing disease.
Topics: Acetates; Administration, Inhalation; Adolescent; Asthma; Bronchodilator Agents; Budesonide; Child; | 2005 |
Budesonide/formoterol in a single inhaler for maintenance and relief in mild-to-moderate asthma: a randomized, double-blind trial.
Topics: Administration, Inhalation; Adolescent; Adult; Aged; Aged, 80 and over; Asthma; Bronchodilator Agent | 2006 |
Protocol-based titration of intravenous terbutaline decreases length of stay in pediatric status asthmaticus.
Topics: Adrenergic beta-Agonists; Albuterol; Asthma; Child; Clinical Protocols; Connecticut; Female; Hospita | 2006 |
[Bronchodilators via metered-dose inhaler with spacer in the pediatric emergency department: what is the dosage?].
Topics: Adolescent; Albuterol; Asthma; Bronchodilator Agents; Child; Child, Preschool; Double-Blind Method; | 2006 |
The use of patch formulation of tulobuterol, a long-acting beta2-adrenoreceptor agonist, in the treatment of severe pediatric asthma.
Topics: Administration, Cutaneous; Adrenergic beta-2 Receptor Agonists; Adrenergic beta-Agonists; Asthma; Be | 2006 |
Effect of budesonide in combination with formoterol for reliever therapy in asthma exacerbations: a randomised controlled, double-blind study.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Asthma; Bronchodilator Agents; Budesonide; Child; Double | 2006 |
Comparison of the clinical efficacy of salmeterol and sustained-release tulobuterol (patch) on inadequately controlled asthma patients on inhaled corticosteroids.
Topics: Administration, Cutaneous; Adrenal Cortex Hormones; Adult; Aged; Albuterol; Anti-Inflammatory Agents | 2006 |
Comparison of the effects of tulobuterol patch and salmeterol in moderate to severe asthma.
Topics: Administration, Cutaneous; Aged; Albuterol; Asthma; Bronchodilator Agents; Cross-Over Studies; Femal | 2006 |
Budesonide/formoterol maintenance plus reliever therapy: a new strategy in pediatric asthma.
Topics: Adrenal Cortex Hormones; Adrenergic beta-Agonists; Anti-Asthmatic Agents; Asthma; Budesonide; Budeso | 2006 |
The influence of the AA 16 beta 2-adrenoceptor polymorphism on systemic and airway responses in asthma.
Topics: Administration, Inhalation; Adrenergic beta-Agonists; Adult; Asthma; Cross-Over Studies; Double-Blin | 2008 |
[The efficacy and safety of tulobuterol tape in mild and moderate persistent asthma patients].
Topics: Adrenergic beta-2 Receptor Antagonists; Adult; Asthma; Bronchodilator Agents; Female; Humans; Male; | 2007 |
Addition of transdermal or inhaled long-acting Beta2-agonists in adult asthmatic patients treated with inhaled corticosteroids: switchover study from tulobuterol patch to salmeterol dry powder inhaler.
Topics: Administration, Cutaneous; Administration, Inhalation; Adrenergic beta-Agonists; Adult; Aged; Albute | 2007 |
New beta-agonist, KWD 2131, compared with terbutaline in asthmatics. A cumulative dose-response study.
Topics: Adrenergic beta-Agonists; Adult; Aerosols; Aged; Asthma; Bronchodilator Agents; Chemical Phenomena; | 1980 |
Histamine-induced bronchospasm. Its reproducibility and usage in clinical evaluation of the sub-threshold bronchodilating dose of a new beta-agonist, KWD 2131.
Topics: Adrenergic beta-Agonists; Adult; Asthma; Bronchial Provocation Tests; Bronchial Spasm; Bronchodilato | 1980 |
Evaluation of the protective effect of a new beta-agonist, KWD 2131, on allergen-induced bronchospasm.
Topics: Adrenergic beta-Agonists; Adult; Allergens; Asthma; Bronchial Provocation Tests; Bronchial Spasm; Cl | 1980 |
[Evaluation of the effectiveness of bricanyl].
Topics: Adrenergic beta-Agonists; Adult; Asthma; Bronchitis; Bronchodilator Agents; Chronic Disease; Clinica | 1980 |
Evaluation of the bronchodilating and antiallergic properties of a beta-adrenoceptor stimulant, KWD 2131, in asthmatic patients.
Topics: Adrenergic beta-Antagonists; Adult; Allergens; Asthma; Bronchodilator Agents; Chronic Disease; Clini | 1980 |
Inhibitory effect of KWD 2131, terbutaline, and DSCG on the immediate and late allergen-induced bronchoconstriction.
Topics: Adrenergic beta-Agonists; Adult; Asthma; Bronchial Provocation Tests; Bronchial Spasm; Clinical Tria | 1981 |
Comparative study of the ventilatory effects of three beta 1-selective blocking agents in asthmatic patients.
Topics: Acebutolol; Adrenergic beta-Antagonists; Adult; Asthma; Atenolol; Bronchi; Clinical Trials as Topic; | 1981 |
Two new beta 2-adrenoceptor agonists, D-2343 and QH 25, studied in asthmatic patients.
Topics: Adrenergic beta-Agonists; Adult; Aged; Albuterol; Animals; Asthma; Bronchodilator Agents; Depression | 1982 |
Does theophylline potentiate inhaled beta 2-agonists?
Topics: Administration, Intranasal; Administration, Oral; Adrenergic beta-Agonists; Asthma; Blood Pressure; | 1982 |
Effects of oral theophylline combined with oral and inhaled beta-2-adrenostimulants in asthmatics.
Topics: Administration, Intranasal; Administration, Oral; Adrenergic beta-Agonists; Adult; Aged; Asthma; Blo | 1982 |
Pafenolol, a highly selective beta 1-adrenoceptor-antagonist, in asthmatic patients: interaction with terbutaline.
Topics: Adrenergic beta-Antagonists; Aged; Asthma; Dose-Response Relationship, Drug; Double-Blind Method; Dr | 1983 |
Effect of prenalterol in asthmatic patients.
Topics: Adrenergic beta-Agonists; Aerosols; Aged; Asthma; Blood Pressure; Dose-Response Relationship, Drug; | 1982 |
Ventilatory and haemodynamic effects of prenalterol and terbutaline in asthmatic patients.
Topics: Adrenergic beta-Agonists; Adult; Asthma; Blood Pressure; Female; Heart Rate; Hemodynamics; Humans; M | 1983 |
Pretreatment of exercise-induced asthma with beta-2 agonists inhaled from RV to TLC or at TLC. A preliminary report.
Topics: Administration, Intranasal; Adult; Asthma; Asthma, Exercise-Induced; Clinical Trials as Topic; Gluco | 1983 |
Selectivity of beta-adrenergic stimulating and blocking agents.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Airway Resistance; Albuterol; Asthma; Bronchi | 1984 |
Effects of xamoterol (ICI 118,587) in asthmatic patients.
Topics: Adrenergic beta-Agonists; Adult; Aged; Asthma; Blood Pressure; Female; Forced Expiratory Volume; Hum | 1984 |
Use of ipratropium bromide in patients with severe airways obstruction.
Topics: Aerosols; Aged; Airway Obstruction; Asthma; Atropine Derivatives; Clinical Trials as Topic; Double-B | 1982 |
Plasma cyclic AMP levels in response to exercise and terbutaline sulphate aerosol in normal and asthmatic subjects.
Topics: Adult; Aerosols; Asthma; Blood Gas Analysis; Cyclic AMP; Humans; Middle Aged; Peak Expiratory Flow R | 1980 |
Arterial plasma histamine levels at rest, and during and after exercise in patients with asthma: effects of terbutaline aerosol.
Topics: Adult; Aerosols; Asthma; Asthma, Exercise-Induced; Cyclic AMP; Forced Expiratory Volume; Histamine; | 1981 |
Terbutaline serum concentrations related to different lung function parameters and beta-receptor function.
Topics: Adult; Asthma; Cyclic AMP; Humans; Lung; Male; Middle Aged; Receptors, Adrenergic; Receptors, Adrene | 1983 |
Comparison of bronchial effects of nabilone and terbutaline in healthy and asthmatic subjects.
Topics: Adult; Asthma; Blood Pressure; Bronchi; Bronchodilator Agents; Dronabinol; Female; Heart Rate; Human | 1983 |
The effects of oral and subcutaneous administration of terbutaline in asthmatic patients.
Topics: Administration, Oral; Adult; Asthma; Cyclic AMP; Forced Expiratory Volume; Humans; Injections, Subcu | 1984 |
Protective effect of oral oxyphenonium bromide, terbutaline and theophylline against the bronchial obstructive effects of inhaled histamine, acetylcholine and propranolol.
Topics: Acetylcholine; Administration, Oral; Adolescent; Adult; Asthma; Bronchi; Bronchial Provocation Tests | 1984 |
Preventive measures in mite asthma. A controlled trial.
Topics: Adolescent; Adult; Asthma; Bedding and Linens; Beds; Clinical Trials as Topic; Dust; Female; Househo | 1983 |
Bronchodilator effects of salbutamol powder administered via Rotahaler and of terbutaline aerosol administered via Misthaler. A comparison study in children with asthma.
Topics: Adolescent; Aerosols; Albuterol; Asthma; Bronchi; Child; Child, Preschool; Clinical Trials as Topic; | 1983 |
Beta-blockers in bronchial asthma: effect of propranolol and pindolol on large and small airways.
Topics: Adult; Asthma; Bronchi; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Male; Maximal | 1983 |
Nebulised terbutaline (Bricanyl) compared to placebo.
Topics: Adult; Asthma; Clinical Trials as Topic; Dose-Response Relationship, Drug; Female; Forced Expiratory | 1983 |
Exercise-induced asthma - laboratory observations.
Topics: Adult; Asthma; Asthma, Exercise-Induced; Bronchial Provocation Tests; Clinical Trials as Topic; Doub | 1983 |
Cardiac response to oral and aerosol administration of beta agonists.
Topics: Administration, Oral; Adolescent; Aerosols; Albuterol; Asthma; Child; Clinical Trials as Topic; Hear | 1983 |
Terbutaline sulfate and isoproterenol sulfate (metered dose aerosols) in the treatment of asthma.
Topics: Adolescent; Adult; Aerosols; Asthma; Clinical Trials as Topic; Double-Blind Method; Humans; Isoprote | 1983 |
Bronchodilation of terbutaline in small doses from a 750 ml spacer. A cumulative dose-response study.
Topics: Adult; Aerosols; Asthma; Clinical Trials as Topic; Dose-Response Relationship, Drug; Double-Blind Me | 1983 |
Effects of inhaled budesonide alone and in combination with low-dose terbutaline in children with exercise-induced asthma.
Topics: Adolescent; Aerosols; Asthma; Asthma, Exercise-Induced; Budesonide; Child; Clinical Trials as Topic; | 1983 |
Comparative efficacy of different methods of nebulising terbutaline.
Topics: Adult; Aerosols; Asthma; Evaluation Studies as Topic; Female; Humans; Intermittent Positive-Pressure | 1983 |
Nifedipine--a calcium channel blocker--in asthmatic patients. Interaction with terbutaline.
Topics: Administration, Oral; Adult; Aged; Asthma; Blood Pressure; Calcium Channel Blockers; Clinical Trials | 1984 |
The effect of subcutaneously administered terbutaline on serum potassium in asymptomatic adult asthmatics.
Topics: Adult; Asthma; Clinical Trials as Topic; Double-Blind Method; Female; Forced Expiratory Volume; Huma | 1984 |
Childhood asthma: improved efficacy of pressurized terbutaline aerosol by use of a 750-ml spacer.
Topics: Adolescent; Aerosols; Asthma; Bronchodilator Agents; Child; Child, Preschool; Clinical Trials as Top | 1984 |
A comparison of sustained-release terbutaline with ordinary salbutamol in bronchial asthma.
Topics: Adult; Aged; Albuterol; Asthma; Clinical Trials as Topic; Delayed-Action Preparations; Double-Blind | 1984 |
Aerosol formulations of terbutaline and isoproterenol in theophylline-stabilized asthmatic patients.
Topics: Adolescent; Adult; Aerosols; Asthma; Clinical Trials as Topic; Double-Blind Method; Female; Humans; | 1984 |
[Effect of the combined use of bricanyl and polomigran on ventilatory disorders in bronchial asthma].
Topics: Adult; Airway Obstruction; Asthma; Bronchodilator Agents; Clinical Trials as Topic; Drug Therapy, Co | 1984 |
Treatment with Bricanyl elixir in obstructive bronchitis and asthma of childhood.
Topics: Adolescent; Asthma; Bronchitis; Child; Child, Preschool; Clinical Trials as Topic; Humans; Infant; T | 1983 |
Pressurised aerosol with conical spacer is an effective alternative to nebuliser in chronic stable asthma.
Topics: Adult; Aerosols; Asthma; Forced Expiratory Volume; Humans; Middle Aged; Terbutaline; Vital Capacity | 1983 |
Bronchoconstriction stimulated by airway cooling. Better protection with combined inhalation of terbutaline sulphate and cromolyn sodium than with either alone.
Topics: Adult; Aerosols; Asthma; Bronchi; Clinical Trials as Topic; Cold Temperature; Cromolyn Sodium; Dose- | 1983 |
Incidence of cardiac arrhythmias in patients taking slow release salbutamol and slow release terbutaline for asthma.
Topics: Adult; Albuterol; Arrhythmias, Cardiac; Asthma; Delayed-Action Preparations; Female; Humans; Male; M | 1984 |
Subcutaneous terbutaline and control of brittle asthma or appreciable morning dipping.
Topics: Adult; Asthma; Circadian Rhythm; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Inje | 1984 |
Nebuhaler versus nebuliser in children with acute asthma.
Topics: Acute Disease; Adolescent; Aerosols; Asthma; Child; Child, Preschool; Humans; Male; Terbutaline | 1984 |
A new beta 2-adrenoceptor agonist--D 2343--with long duration. Inhalation comparison with terbutaline in asthmatics.
Topics: Asthma; Heart Rate; Humans; Octopamine; Respiratory Function Tests; Respiratory Therapy; Terbutaline | 1984 |
[Comparative effects of terbutaline sulphate and ipratropium bromide on the respiratory system (author's transl)].
Topics: Aerosols; Asthma; Atropine Derivatives; Bronchitis; Bronchodilator Agents; Clinical Trials as Topic; | 1980 |
A comparative study of aerosolized terbutaline and subcutaneously administered epinephrine in the treatment of acute bronchial asthma.
Topics: Acute Disease; Administration, Oral; Adult; Aerosols; Asthma; Blood Pressure; Epinephrine; Female; F | 1984 |
Bronchodilator effect of terbutaline aerosol is not affected by propellant vapour pressure or dose volume.
Topics: Aerosols; Aged; Asthma; Female; Humans; Male; Maximal Expiratory Flow Rate; Middle Aged; Pressure; R | 1983 |
Comparison of salbutamol powder with terbutaline aerosol administered with a tube spacer in asthmatic children.
Topics: Adolescent; Aerosols; Albuterol; Asthma; Bronchi; Child; Forced Expiratory Volume; Humans; Maximal M | 1983 |
Influence of an extension tube on the bronchodilator efficacy of terbutaline delivered from a metered dose inhaler.
Topics: Adolescent; Adult; Aerosols; Aged; Asthma; Equipment and Supplies; Female; Forced Expiratory Flow Ra | 1984 |
Cumulative dose response study comparing clinical effects of two doses of terbutaline sulphate administered via a 750 ml spacer to asthmatic patients.
Topics: Adult; Asthma; Dose-Response Relationship, Drug; Female; Humans; Isoproterenol; Male; Middle Aged; R | 1984 |
Cardiovascular effects of intramuscular or inhaled terbutaline in asthmatics.
Topics: Adolescent; Adult; Aged; Asthma; Blood Pressure; Dose-Response Relationship, Drug; Female; Heart Rat | 1984 |
Cardioselectivity of atenolol and metoprolol. A study in asthmatic patients.
Topics: Adult; Aged; Asthma; Atenolol; Blood Pressure; Clinical Trials as Topic; Double-Blind Method; Female | 1981 |
Terbutaline in asthmatic children--a comparison of the conventional "inhaler" and "spacer" methods of administration.
Topics: Aerosols; Asthma; Child; Child, Preschool; Clinical Trials as Topic; Double-Blind Method; Female; Hu | 1982 |
Ventilatory and haemodynamic effects of terbutaline infusion during beta 1-selective blockade with metoprolol and acebutolol in asthmatic patients.
Topics: Acebutolol; Adult; Asthma; Clinical Trials as Topic; Double-Blind Method; Female; Forced Expiratory | 1982 |
A comparative double-blind study of the bronchodilator effects and side effects of inhaled fenoterol and terbutaline administered in equipotent doses.
Topics: Adolescent; Adult; Airway Resistance; Asthma; Clinical Trials as Topic; Dose-Response Relationship, | 1982 |
A comparison of the effects of different methods of administration of beta-2-sympathomimetics in patients with asthma.
Topics: Administration, Oral; Albuterol; Asthma; Clinical Trials as Topic; Double-Blind Method; Humans; Resp | 1982 |
Inhibition of the bronchial response to respiratory heat exchange by increasing doses of terbutaline sulphate.
Topics: Adult; Asthma; Bronchi; Clinical Trials as Topic; Cold Temperature; Dose-Response Relationship, Drug | 1982 |
Combined treatment with sustained-release theophylline and beta2-adrenoceptor-stimulating agents in chronic childhood asthma.
Topics: Adolescent; Albuterol; Asthma; Child; Chronic Disease; Clinical Trials as Topic; Delayed-Action Prep | 1981 |
Therapeutic modulation of bronchial hyperreactivity.
Topics: Asthma; Bronchodilator Agents; Clinical Trials as Topic; Cromolyn Sodium; Double-Blind Method; Human | 1982 |
Terbutaline aerosol given through pear spacer in acute severe asthma.
Topics: Adolescent; Adult; Aerosols; Aged; Asthma; Female; Forced Expiratory Volume; Heart Rate; Humans; Mal | 1982 |
Aerosolized terbutaline in asthmatics: development of subsensitivity with long-term administration.
Topics: Adrenal Cortex Hormones; Adult; Aerosols; Aged; Asthma; Bronchodilator Agents; Dose-Response Relatio | 1982 |
Long-term effects of a tube extension on bronchodilator treatment with pressurized aerosol.
Topics: Adult; Aerosols; Aged; Asthma; Female; Humans; Long-Term Care; Male; Middle Aged; Outcome and Proces | 1982 |
Aerosol treatment of bronchoconstriction in children, with or without a tube spacer.
Topics: Aerosols; Asthma; Asthma, Exercise-Induced; Bronchial Spasm; Child; Double-Blind Method; Female; For | 1983 |
Effects of terbutaline sulphate aerosol on bronchodilator response and lung mucociliary clearance in patients with mild stable asthma.
Topics: Adult; Aerosols; Asthma; Bronchodilator Agents; Cilia; Double-Blind Method; Female; Forced Expirator | 1983 |
Interaction between corticosteroids and beta 2-agonists in acute asthma.
Topics: Acute Disease; Adult; Aged; Asthma; Drug Therapy, Combination; Female; Forced Expiratory Volume; Hum | 1982 |
Effect on lung function of budesonide by inhalation, terbutaline s.c. and placebo given simultaneously or as single treatments.
Topics: Adult; Aged; Asthma; Budesonide; Drug Therapy, Combination; Female; Humans; Injections, Subcutaneous | 1982 |
Management of acute asthma in childhood. A randomized evaluation of beta-adrenergic agents.
Topics: Acute Disease; Administration, Intranasal; Adolescent; Adult; Amino Alcohols; Aminophylline; Asthma; | 1980 |
Clinical trial of two inhalation techniques for pressurized aerosols.
Topics: Adolescent; Adult; Aerosols; Aged; Asthma; Child; Clinical Trials as Topic; Female; Humans; Male; Mi | 1980 |
Comparison of fenoterol and terbutaline administered by intermittent positive pressure breathing.
Topics: Aged; Asthma; Clinical Trials as Topic; Double-Blind Method; Ethanolamines; Female; Fenoterol; Heart | 1980 |
Theophylline and aerosolized terbutaline in the treatment of bronchial asthma. Double-blind comparison of optimal doses.
Topics: Adult; Aerosols; Aged; Asthma; Clinical Trials as Topic; Double-Blind Method; Drug Therapy, Combinat | 1980 |
Inhibition of antigen-induced bronchoconstriction with reproterol, a new beta agonist-xanthine derivative.
Topics: Adult; Aged; Antigens; Asthma; Bronchial Provocation Tests; Clinical Trials as Topic; Double-Blind M | 1981 |
Comparison of intravenous and inhaled terbutaline in the treatment of asthma.
Topics: Adult; Aerosols; Airway Obstruction; Asthma; Clinical Trials as Topic; Dose-Response Relationship, D | 1981 |
Value of combining B2 sympathomimetic metered aerosol and oral theophylline in children with asthma.
Topics: Administration, Oral; Adolescent; Aerosols; Asthma; Child; Child, Preschool; Clinical Trials as Topi | 1981 |
Effectiveness of terbutaline and theophylline alone and in combination in exercise-induced bronchospasm.
Topics: Adolescent; Adult; Asthma; Asthma, Exercise-Induced; Child; Clinical Trials as Topic; Double-Blind M | 1981 |
Clinical trial of a modified inhaler for pressurized aerosols.
Topics: Adult; Aerosols; Aged; Asthma; Bronchodilator Agents; Clinical Trials as Topic; Female; Forced Expir | 1981 |
[Postoperative respiratory therapy: bronchospasmolytic activity and side-effects of some recently introduced beta-sympatheticomimetic agents (author's transl)].
Topics: Adult; Aged; Asthma; Bronchial Spasm; Bronchitis; Clinical Trials as Topic; Drug Combinations; Ethan | 1981 |
Comparison of oral and aerosol adrenergic bronchodilators in asthma.
Topics: Administration, Oral; Adolescent; Aerosols; Asthma; Child; Clinical Trials as Topic; Forced Expirato | 1981 |
Comparison of inhaled and intravenous terbutaline in acute severe asthma.
Topics: Acute Disease; Aerosols; Asthma; Clinical Trials as Topic; Double-Blind Method; Humans; Injections, | 1981 |
[Should stable asthma be treated with a nebulizer or spray?].
Topics: Adult; Aerosols; Asthma; Asthma, Exercise-Induced; Child; Clinical Trials as Topic; Humans; Middle A | 1981 |
Terbutaline depot tablets in asthma. A clinical evaluation.
Topics: Adolescent; Adult; Asthma; Bronchodilator Agents; Clinical Trials as Topic; Delayed-Action Preparati | 1981 |
The effect of terbutaline sulphate on exercise-induced asthma in children.
Topics: Aerosols; Asthma; Asthma, Exercise-Induced; Child; Clinical Trials as Topic; Female; Humans; Male; P | 1982 |
Do oral and inhaled terbutaline have different effects on the lung?
Topics: Administration, Oral; Adult; Aerosols; Asthma; Clinical Trials as Topic; Double-Blind Method; Female | 1982 |
A comparison of sustained-release terbutaline and ordinary terbutaline in bronchial asthma.
Topics: Adult; Aged; Asthma; Clinical Trials as Topic; Delayed-Action Preparations; Double-Blind Method; Fem | 1982 |
Effect of oral terbutaline on exercise-induced asthma.
Topics: Administration, Oral; Asthma; Asthma, Exercise-Induced; Blood Pressure; Child; Female; Forced Expira | 1982 |
A double-blind comparative study of the effects of aerosolized isoproterenol and terbutaline in adult asthmatic patients.
Topics: Adolescent; Adult; Aerosols; Asthma; Blood Pressure; Double-Blind Method; Electrocardiography; Femal | 1982 |
Cumulative dose-response study comparing terbutaline pressurized aerosol administered via a pearshaped spacer and terbutaline in a nebulized solution.
Topics: Adult; Aerosols; Asthma; Dose-Response Relationship, Drug; Female; Forced Expiratory Volume; Humans; | 1982 |
Bioavailability of theophylline from three different tablets in asthmatic patients and their bronchodilating effects in combination with terbutaline inhalation.
Topics: Administration, Intranasal; Administration, Oral; Asthma; Biological Availability; Bronchodilator Ag | 1982 |
Dose response of subcutaneous terbutaline and epinephrine in children with acute asthma.
Topics: Adolescent; Airway Obstruction; Akathisia, Drug-Induced; Asthma; Blood Pressure; Child; Dose-Respons | 1981 |
Ventilatory effects of ordinary and slow-release tablets of metoprolol in asthmatic patients.
Topics: Adolescent; Adult; Asthma; Delayed-Action Preparations; Female; Forced Expiratory Volume; Heart Rate | 1981 |
Sites of airway dilatation in asthma following inhaled versus subcutaneous terbutaline. Comparison of physiologic tests with radionuclide lung images.
Topics: Aerosols; Airway Obstruction; Airway Resistance; Asthma; Humans; Injections, Subcutaneous; Lung; Lun | 1980 |
A comparison of oral terbutaline and fenoterol in asthma.
Topics: Administration, Oral; Asthma; Blood Pressure; Bronchodilator Agents; Drug Tolerance; Ethanolamines; | 1980 |
Bronchodilator effects of low doses of oral theophylline and terbutaline in asthmatic subjects.
Topics: Adult; Aged; Asthma; Bronchodilator Agents; Dose-Response Relationship, Drug; Female; Hemodynamics; | 1980 |
Bronchodilation and inhibition of induced asthma by adrenergic agonists.
Topics: Adolescent; Adult; Asthma; Asthma, Exercise-Induced; Bronchodilator Agents; Forced Expiratory Volume | 1981 |
Influence of budesonide on the response to inhaled terbutaline in children with mild asthma.
Topics: Administration, Inhalation; Adolescent; Albuterol; Asthma; Bronchodilator Agents; Budesonide; Child; | 1995 |
The psychological factors associated with poor compliance with treatment in asthma.
Topics: Administration, Inhalation; Adolescent; Adult; Aged; Analysis of Variance; Anxiety; Asthma; Bronchod | 1995 |
Comparison of the efficacy, tolerability and patient acceptability of once-daily bambuterol tablets against twice-daily controlled release salbutamol in nocturnal asthma. ACROBATICS Research Group.
Topics: Adolescent; Adrenergic beta-Agonists; Adult; Aged; Albuterol; Asthma; Bronchodilator Agents; Cross-O | 1995 |
Use of a fixed combination beta 2-agonist and steroid dry powder inhaler in asthma.
Topics: Adolescent; Adult; Asthma; Bronchodilator Agents; Budesonide; Cross-Over Studies; Double-Blind Metho | 1995 |
Costs and effects of inhaled corticosteroids and bronchodilators in asthma and chronic obstructive pulmonary disease.
Topics: Adult; Asthma; Beclomethasone; Cost-Benefit Analysis; Double-Blind Method; Drug Therapy, Combination | 1995 |
Comparison of Bricanyl Turbuhaler and Ventolin Rotahaler in children with asthma.
Topics: Albuterol; Asthma; Child; Child, Preschool; Cross-Over Studies; Drug Tolerance; Female; Humans; Lung | 1995 |
Dose potency relationship of terbutaline inhaled via Turbuhaler or via a pressurized metered dose inhaler.
Topics: Administration, Inhalation; Adolescent; Adult; Aged; Asthma; Cross-Over Studies; Female; Humans; Mal | 1995 |
Metered dose inhaler and nebuliser in acute asthma.
Topics: Acute Disease; Adolescent; Asthma; Child; Child, Preschool; Drug Delivery Systems; Female; Humans; M | 1995 |
One month treatment with the once daily oral beta 2-agonist bambuterol in asthmatic patients.
Topics: Administration, Oral; Adrenergic beta-Agonists; Asthma; Bronchodilator Agents; Double-Blind Method; | 1995 |
Improvement of inhaler efficacy by home-made spacer.
Topics: Adolescent; Adult; Aerosols; Aged; Asthma; Equipment Design; Female; Humans; Male; Middle Aged; Nebu | 1993 |
Terbutaline powder for acute asthma.
Topics: Administration, Inhalation; Adolescent; Asthma; Child; Child, Preschool; Humans; Nebulizers and Vapo | 1995 |
Influence of treatment on peak expiratory flow and its relation to airway hyperresponsiveness and symptoms. The Dutch CNSLD Study Group.
Topics: Adolescent; Adult; Asthma; Beclomethasone; Circadian Rhythm; Double-Blind Method; Drug Therapy, Comb | 1994 |
Bambuterol in the treatment of asthma. A placebo-controlled comparison of once-daily morning vs evening administration.
Topics: Adolescent; Adult; Aged; Asthma; Bronchodilator Agents; Cholinesterases; Cross-Over Studies; Double- | 1995 |
[Effectiveness of comprehensive therapy of broncho-obstructive syndrome].
Topics: Asthma; Cefotaxime; Drug Therapy, Combination; Evaluation Studies as Topic; Humans; Lung Diseases, O | 1994 |
Ease of handling and efficacy of Bricanyl Turbuhaler in Asian asthmatic children.
Topics: Administration, Inhalation; Adolescent; Asia; Asthma; Child; Female; Humans; Male; Nebulizers and Va | 1994 |
Comparison of terbutaline and placebo from a pressurised metered dose inhaler and a dry powder inhaler in a subgroup of patients with asthma.
Topics: Albuterol; Asthma; Chlorofluorocarbons; Dose-Response Relationship, Drug; Double-Blind Method; Drug | 1994 |
Continuous versus intermittent nebulized terbutaline: plasma levels and effects.
Topics: Administration, Inhalation; Adolescent; Aerosols; Asthma; Blood Pressure; Child; Double-Blind Method | 1995 |
Salmeterol compared with slow-release terbutaline in nocturnal asthma. A multicenter, randomized, double-blind, double-dummy, sequential clinical trial. French Multicenter Study Group.
Topics: Adolescent; Adrenergic beta-Agonists; Adult; Aged; Albuterol; Asthma; Delayed-Action Preparations; D | 1994 |
Effect of regular terbutaline and budesonide on bronchial reactivity to allergen challenge.
Topics: Adolescent; Adult; Allergens; Asthma; Bronchi; Bronchial Provocation Tests; Budesonide; Dose-Respons | 1994 |
Assessment of the ability of young children to use a powder inhaler device (Turbuhaler).
Topics: Age Factors; Asthma; Child; Child, Preschool; Humans; Nebulizers and Vaporizers; Patient Compliance; | 1994 |
Terbutaline via pressurised metered dose inhaled (P-MDI) and Turbuhaler in highly reactive asthmatic patients.
Topics: Adult; Asthma; Bronchoconstriction; Cross-Over Studies; Female; Humans; Male; Nebulizers and Vaporiz | 1994 |
The protective effects of ipratropium bromide and terbutaline on distilled water-induced bronchoconstriction.
Topics: Administration, Inhalation; Adolescent; Adult; Asthma; Bronchoconstriction; Dose-Response Relationsh | 1994 |
Patient compliance with inhaled medication: does combining beta-agonists with corticosteroids improve compliance?
Topics: Administration, Inhalation; Adult; Aerosols; Asthma; Bronchodilator Agents; Budesonide; Drug Combina | 1994 |
Nonbronchodilator effects of inhaled beta 2 agonists. Greater protection against adenosine monophosphate- than methacholine-induced bronchoconstriction in asthma.
Topics: Adenosine Monophosphate; Administration, Inhalation; Adult; Asthma; Bronchi; Bronchoconstriction; Do | 1994 |
Effects of reducing or discontinuing inhaled budesonide in patients with mild asthma.
Topics: Administration, Inhalation; Adult; Asthma; Bronchial Hyperreactivity; Bronchodilator Agents; Budeson | 1994 |
Beta 2-agonists and running economy in prepubertal boys.
Topics: Administration, Inhalation; Analysis of Variance; Asthma; Child; Exercise Test; Forced Expiratory Vo | 1994 |
Therapeutic equivalence between bambuterol, 10 mg once daily, and terbutaline controlled release, 5 mg twice daily, in mild to moderate asthma.
Topics: Adolescent; Adult; Asthma; Bronchodilator Agents; Delayed-Action Preparations; Double-Blind Method; | 1993 |
[Efficacy of a powder inhaler (Turbuhaler) in moderate asthmatic crises in children].
Topics: Acute Disease; Administration, Inhalation; Adolescent; Aerosols; Airway Resistance; Asthma; Child; C | 1993 |
Bronchodilating effect of terbutaline powder in acute severe bronchial obstruction.
Topics: Acute Disease; Administration, Inhalation; Analysis of Variance; Asthma; Female; Forced Expiratory V | 1994 |
Variability of bronchodilator response and effects of inhaled corticosteroid treatment in obstructive airways disease. Dutch CNSLD Study Group.
Topics: Administration, Inhalation; Adolescent; Adult; Albuterol; Asthma; Beclomethasone; Bronchi; Bronchial | 1993 |
A multicentre comparison of the efficacy of terbutaline Turbuhaler and salbutamol pressurized metered dose inhaler in hot, humid regions.
Topics: Aerosols; Albuterol; Asthma; Child; Female; Hot Temperature; Humans; Humidity; Male; Middle Aged; Ne | 1994 |
Comparison of inhaled terbutaline administered by either the Turbuhaler dry powder inhaler or a metered-dose inhaler with spacer in preschool children with asthma.
Topics: Administration, Inhalation; Asthma; Child; Child, Preschool; Double-Blind Method; Equipment Design; | 1994 |
Bambuterol: effective in nocturnal asthma.
Topics: Adult; Asthma; Bronchodilator Agents; Circadian Rhythm; Double-Blind Method; Female; Humans; Male; M | 1993 |
Effect of preservative on the efficacy of terbutaline nebuliser solution in atopic asthma.
Topics: Administration, Inhalation; Adult; Asthma; Bronchoconstriction; Double-Blind Method; Female; Forced | 1993 |
Airways hyperresponsiveness, bronchodilator response, allergy and smoking predict improvement in FEV1 during long-term inhaled corticosteroid treatment. Dutch CNSLD Study Group.
Topics: Administration, Inhalation; Adult; Asthma; Beclomethasone; Bronchi; Bronchial Hyperreactivity; Doubl | 1993 |
Inhaled beta 2-agonist and positive expiratory pressure in bronchial asthma. Influence on airway resistance and functional residual capacity.
Topics: Administration, Inhalation; Airway Resistance; Asthma; Female; Functional Residual Capacity; Humans; | 1993 |
A placebo-controlled dose-finding study with bambuterol in elderly patients with asthma.
Topics: Aged; Asthma; Bronchodilator Agents; Cholinesterases; Delayed-Action Preparations; Dose-Response Rel | 1993 |
Terbutaline controlled-release tablets and ipratropium aerosol in nocturnal asthma.
Topics: Adult; Aerosols; Asthma; Circadian Rhythm; Delayed-Action Preparations; Double-Blind Method; Drug Th | 1993 |
Regular inhaled beta agonist in asthma: effects on exacerbations and lung function.
Topics: Administration, Inhalation; Adolescent; Adult; Albuterol; Asthma; Bronchoconstriction; Double-Blind | 1993 |
Inhaled ipratropium bromide and terbutaline in asthmatic children.
Topics: Administration, Inhalation; Asthma; Child; Child, Preschool; Drug Administration Schedule; Drug Ther | 1993 |
Dyspnea in acute asthma: relationship with other clinical and physiologic variables.
Topics: Administration, Inhalation; Adult; Aged; Aged, 80 and over; Airway Obstruction; Aminophylline; Asthm | 1993 |
Rebound airway obstruction and responsiveness after cessation of terbutaline: effects of budesonide.
Topics: Administration, Inhalation; Administration, Topical; Adolescent; Adrenergic beta-Agonists; Adult; Ae | 1996 |
A 4-week comparison of salmeterol and terbutaline in adult asthma.
Topics: Adolescent; Adult; Aged; Albuterol; Asthma; Bronchodilator Agents; Female; Forced Expiratory Volume; | 1995 |
Is delayed introduction of inhaled corticosteroids harmful in patients with obstructive airways disease (asthma and COPD)? The Dutch CNSLD Study Group. The Dutch Chronic Nonspecific Lung Disease Study Groups.
Topics: Administration, Inhalation; Adolescent; Adrenergic beta-Agonists; Adult; Asthma; Beclomethasone; Bro | 1996 |
A 1-year comparison of turbuhaler vs pressurized metered-dose inhaler in asthmatic patients.
Topics: Administration, Inhalation; Adrenergic beta-Agonists; Adult; Asthma; Bronchodilator Agents; Budesoni | 1996 |
A comparison of the clinical efficacy and patient acceptability of terbutaline Turbuhaler and salbutamol Rotahaler, in adult patients with asthma.
Topics: Adolescent; Adult; Albuterol; Asthma; Bronchodilator Agents; Cross-Over Studies; Female; Follow-Up S | 1996 |
Dose response to inhaled terbutaline powder and peak inspiratory flow through Turbuhaler in children with mild to moderate asthma.
Topics: Administration, Inhalation; Adrenergic beta-Agonists; Age Factors; Asthma; Child; Child, Preschool; | 1996 |
Terbutaline nebulization and epinephrine injection in treating acute asthmatic children.
Topics: Administration, Inhalation; Asthma; Child; Epinephrine; Female; Humans; Injections, Subcutaneous; Ma | 1996 |
Efficacy and side effects of beta 2-agonists by inhaled route in acute asthma in children: comparison of salbutamol, terbutaline, and fenoterol.
Topics: Administration, Inhalation; Adolescent; Adrenergic beta-Agonists; Albuterol; Asthma; Bronchodilator | 1996 |
Effect of regular terbutaline on the airway response to inhaled budesonide.
Topics: Adrenergic beta-Agonists; Adult; Aerosols; Asthma; Bronchial Provocation Tests; Bronchodilator Agent | 1996 |
Sodium cromoglycate as a replacement for inhaled corticosteroids in mild-to-moderate childhood asthma.
Topics: Administration, Inhalation; Adolescent; Adrenal Cortex Hormones; Asthma; Child; Child, Preschool; Cr | 1996 |
Adenosine monophosphate and histamine induced bronchoconstriction: repeatability and protection by terbutaline.
Topics: Adenosine Monophosphate; Adult; Asthma; Bronchial Provocation Tests; Bronchoconstriction; Bronchodil | 1997 |
Effects of the long acting beta agonist formoterol on asthma control in asthmatic patients using inhaled corticosteroids. The Netherlands and Canadian Formoterol Study Investigators.
Topics: Adrenergic beta-Agonists; Adult; Asthma; Bronchodilator Agents; Double-Blind Method; Drug Therapy, C | 1997 |
Influence of inspiratory capacity on bronchodilatation via Turbuhaler or pressurized metered-dose inhaler in asthmatic children: a comparison.
Topics: Adolescent; Adult; Asthma; Bronchi; Bronchodilator Agents; Child; Child, Preschool; Double-Blind Met | 1997 |
Rapid reversibility of the allergen-induced pulmonary late-phase reaction by an intravenous beta2-agonist.
Topics: Adrenergic Agonists; Adult; Allergens; Asthma; Bronchial Spasm; Bronchodilator Agents; Forced Expira | 1998 |
Effect of an inhaled glucocorticosteroid on mast cell and smooth muscle beta 2 adrenergic tolerance in mild asthma.
Topics: Adenosine Monophosphate; Administration, Inhalation; Administration, Topical; Adrenergic beta-Agonis | 1998 |
Effects of treatment with formoterol on bronchoprotection against methacholine.
Topics: Adolescent; Adrenergic beta-Agonists; Adult; Aged; Anti-Inflammatory Agents; Asthma; Bronchoconstric | 1998 |
Effect of salmeterol treatment on nitric oxide level in exhaled air and dose-response to terbutaline in children with mild asthma.
Topics: Adolescent; Adrenergic beta-Agonists; Albuterol; Asthma; Breath Tests; Bronchodilator Agents; Child; | 1998 |
Hemodynamic, cardiac, and electrolyte effects of low-dose aerosolized terbutaline sulfate in asthmatic patients.
Topics: Administration, Inhalation; Adrenergic beta-Agonists; Adult; Aerosols; Aldosterone; Asthma; Bicarbon | 1998 |
[Comparison of the effect of subcutaneous injection of adrenaline and terbutaline in asthma crisis in infants].
Topics: Asthma; Bronchodilator Agents; Child, Preschool; Epinephrine; Female; Humans; Infant; Injections, Su | 1998 |
Tolerability to high doses of formoterol and terbutaline via Turbuhaler for 3 days in stable asthmatic patients.
Topics: Administration, Inhalation; Adrenergic beta-Agonists; Adult; Aged; Analysis of Variance; Asthma; Blo | 1998 |
Risk of overtreatment with current peak flow criteria in self-management plans. Dutch CNSLD Study Group. Chronic Non-Specific Lung Disease.
Topics: Administration, Inhalation; Adolescent; Adult; Asthma; Beclomethasone; Bronchodilator Agents; Dose-R | 1998 |
Low-dose formoterol Turbuhaler (Oxis) b.i.d., a 3-month placebo-controlled comparison with terbutaline (q.i.d.).
Topics: Adolescent; Adrenergic beta-Agonists; Adult; Aged; Asthma; Bronchodilator Agents; Double-Blind Metho | 1998 |
Beta2-adrenoceptor polymorphism and bronchoprotective sensitivity with regular short- and long-acting beta2-agonist therapy.
Topics: Adolescent; Adrenergic beta-Agonists; Adult; Asthma; Bronchoconstrictor Agents; Bronchodilator Agent | 1999 |
Comparison of oral bambuterol and inhaled salmeterol in patients with symptomatic asthma and using inhaled corticosteroids.
Topics: Administration, Inhalation; Administration, Oral; Adolescent; Adrenergic beta-Agonists; Adult; Aged; | 1999 |
Peak expiratory flow rate guided protocol did not improve outcome in emergency room asthma.
Topics: Acute Disease; Adult; Algorithms; Asthma; Bronchodilator Agents; Decision Trees; Emergency Treatment | 1998 |
Randomised placebo controlled trial of beta agonist dose reduction in asthma.
Topics: Administration, Inhalation; Adolescent; Adrenergic beta-Agonists; Adult; Aged; Asthma; Bronchodilato | 1999 |
Randomised trial of an inhaled beta2 agonist, inhaled corticosteroid and their combination in the treatment of asthma.
Topics: Administration, Inhalation; Adolescent; Adrenergic beta-Agonists; Adult; Anti-Inflammatory Agents; A | 1999 |
Effects of inhaled beta agonist and corticosteroid treatment on nuclear transcription factors in bronchial mucosa in asthma.
Topics: Administration, Inhalation; Adolescent; Adrenergic beta-Agonists; Adult; Aged; Anti-Inflammatory Age | 1999 |
A comparison of two long-acting beta-agonists, oral bambuterol and inhaled salmeterol, in the treatment of moderate to severe asthmatic patients with nocturnal symptoms. The French Bambuterol Study Group.
Topics: Administration, Inhalation; Administration, Oral; Adrenergic beta-Agonists; Adult; Aged; Albuterol; | 1999 |
Pharmacokinetics of bambuterol during oral administration to asthmatic children.
Topics: Administration, Oral; Area Under Curve; Asthma; Bronchodilator Agents; Child; Child, Preschool; Chol | 1999 |
Tolerance to beta-agonists during acute bronchoconstriction.
Topics: Acute Disease; Adolescent; Adrenergic beta-Agonists; Adult; Airway Obstruction; Albuterol; Asthma; B | 1999 |
Variability in lung deposition of inhaled drug, within and between asthmatic patients, with a pMDI and a dry powder inhaler, Turbuhaler.
Topics: Administration, Inhalation; Adult; Anti-Asthmatic Agents; Asthma; Bronchi; Bronchoconstrictor Agents | 2000 |
Changes in transfer factor of the lung in response to bronchodilatation.
Topics: Adult; Asthma; Bronchial Provocation Tests; Bronchodilator Agents; Carbon Monoxide; Female; Humans; | 2000 |
Comparative study using oral solutions of bambuterol once daily or terbutaline three times daily in 2-5-year-old children with asthma. Bambuterol Multicentre Study Group.
Topics: Administration, Oral; Asthma; Blood Pressure; Bronchodilator Agents; Child; Child, Preschool; Circad | 2000 |
Effects of terbutaline and budesonide on sputum cells and bronchial hyperresponsiveness in asthma.
Topics: Administration, Topical; Adolescent; Adrenergic beta-Agonists; Adult; Anti-Inflammatory Agents; Asth | 2000 |
One-year safety study with bambuterol once daily and terbutaline three times daily in 2-12-year-old children with asthma. The Bambuterol Multicentre Study Group.
Topics: Administration, Oral; Asthma; Blood Pressure; Bronchodilator Agents; Child; Child, Preschool; Drug A | 2000 |
Detection and treatment of early asthma.
Topics: Administration, Inhalation; Adolescent; Adult; Asthma; Biomarkers; Blood Proteins; Bronchodilator Ag | 2000 |
Lung function response to cold air challenge in asthmatic and healthy children of 2-5 years of age.
Topics: Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Bronchodilator Agents; Child, Presch | 2000 |
Bronchodilator tolerance and rebound bronchoconstriction during regular inhaled beta-agonist treatment.
Topics: Administration, Inhalation; Adolescent; Adult; Aged; Asthma; Bronchoconstriction; Bronchodilator Age | 2000 |
Comparison of formoterol and terbutaline for as-needed treatment of asthma: a randomised trial.
Topics: Administration, Inhalation; Adolescent; Adrenergic beta-Agonists; Adult; Aged; Analysis of Variance; | 2001 |
The effectiveness of high-dose inhaled budesonide therapy in the treatment of acute asthma exacerbations in children.
Topics: Acute Disease; Administration, Inhalation; Administration, Oral; Anti-Inflammatory Agents; Asthma; B | 2001 |
[Inhaled budesonide for severe asthma at high altitude].
Topics: Administration, Inhalation; Adrenergic beta-Agonists; Adult; Altitude; Asthma; Budesonide; Double-Bl | 2000 |
Protection against cold air and exercise-induced bronchoconstriction while on regular treatment with Oxis.
Topics: Adult; Analysis of Variance; Anti-Asthmatic Agents; Asthma; Bronchoconstriction; Cold Temperature; C | 2001 |
Comparison of the acute effects of salbutamol and terbutaline on heart rate variability in adult asthmatic patients.
Topics: Administration, Inhalation; Adult; Albuterol; Asthma; Autonomic Nervous System; Cross-Over Studies; | 2001 |
Discriminative capacity of bronchodilator response measured with three different lung function techniques in asthmatic and healthy children aged 2 to 5 years.
Topics: Administration, Inhalation; Age Factors; Airway Resistance; Asthma; Bronchodilator Agents; Case-Cont | 2001 |
A single dose of nebulized budesonide decreases exhaled nitric oxide in children with acute asthma.
Topics: Adolescent; Asthma; Blood Pressure; Bronchodilator Agents; Budesonide; Case-Control Studies; Child; | 2001 |
A cost-effectiveness study comparing the as-needed use of formoterol (Oxis) and terbutaline (Bricanyl) in patients with moderate to severe asthma.
Topics: Acute Disease; Anti-Asthmatic Agents; Asthma; Confidence Intervals; Cost of Illness; Cost Savings; C | 2001 |
Lung deposition and protective effect of terbutaline delivered from pressurized metered-dose inhalers and the Turbuhaler in asthmatic individuals.
Topics: Adult; Asthma; Bronchodilator Agents; Cross-Over Studies; Double-Blind Method; Female; Humans; Lung; | 2001 |
Initial improvements in lung function and bronchial hyperresponsiveness are maintained during 5 years of treatment with inhaled beclomethasone dipropionate and terbutaline.
Topics: Administration, Inhalation; Adult; Anti-Asthmatic Agents; Asthma; Beclomethasone; Bronchial Hyperrea | 2002 |
Effect of patient education on self-management skills and health status in patients with asthma: a randomized trial.
Topics: Adult; Albuterol; Asthma; Attitude to Health; Bronchodilator Agents; Female; Hospitalization; Humans | 2002 |
Selective beta2-receptor agonists for the treatment of asthma--therapeutic breakthrough or advertising ploy? A commentary.
Topics: Adolescent; Adrenergic beta-Agonists; Adult; Aged; Asthma; Child; Child, Preschool; Clinical Trials | 1976 |
Comparison of rimiterol and terbutaline, given by aerosol, in a long-term study.
Topics: Aerosols; Asthma; Bronchitis; Catechols; Chronic Disease; Drug Evaluation; Female; Humans; Isoproter | 1977 |
Rimiterol: a review of its pharmacological properties and therapeutic efficacy in asthma.
Topics: Absorption; Administration, Oral; Aerosols; Albuterol; Animals; Asthma; Bronchodilator Agents; Catec | 1977 |
[Treatment of acute asthma. Comparison of the effectiveness of corticosteroids and of a combination of corticosteroids and an adrenergic beta-stimulant (author's transl)].
Topics: Adrenal Cortex Hormones; Adrenergic beta-Agonists; Asthma; Blood Gas Analysis; Blood Pressure; Cosyn | 1977 |
The rapidity of bronchodilatation. A comparison of isoprenaline, terbutaline and rimiterol.
Topics: Adult; Aged; Asthma; Bronchodilator Agents; Bronchospirometry; Catechols; Clinical Trials as Topic; | 1978 |
Long-term beta2 bronchodilator therapy and the question of tolerance.
Topics: Adrenergic beta-Agonists; Asthma; Clinical Trials as Topic; Ephedrine; Fenoterol; Forced Expiratory | 1978 |
A comparison of a theophylline-ephedrine combination with terbutaline.
Topics: Adult; Asthma; Clinical Trials as Topic; Cyclic AMP; Drug Combinations; Ephedrine; Humans; Lung; Ter | 1978 |
Subsensitivity of beta responses on terbutaline therapy.
Topics: Asthma; Blood Pressure; Bronchitis; Clinical Trials as Topic; Cyclic AMP; Humans; Lactates; Respirat | 1978 |
Evaluation of a new oral beta2-adrenoceptor stimulant bronchodilator, terbutaline.
Topics: Administration, Oral; Adrenergic beta-Agonists; Adult; Aged; Airway Obstruction; Asthma; Blood Press | 1975 |
A comparative study of subcutaneously administered terbutaline and epinephrine in the treatment of acute bronchial asthma.
Topics: Acute Disease; Adult; Asthma; Blood Pressure; Clinical Trials as Topic; Epinephrine; Heart Rate; Hum | 1977 |
Aerosolized terbutaline sulfate--an evalution of efficacy and side effects in patients with reversible airway disease.
Topics: Adult; Aerosols; Aged; Asthma; Clinical Trials as Topic; Drug Evaluation; Female; Forced Expiratory | 1977 |
Assessing bronchodilator responsiveness.
Topics: Adolescent; Asthma; Bronchi; Child; Clinical Trials as Topic; Drug Evaluation; Ephedrine; Female; Hu | 1977 |
Comparison of subcutaneous terbutaline with epinephrine in the treatment of asthma in children.
Topics: Adolescent; Asthma; Blood Pressure; Child; Child, Preschool; Clinical Trials as Topic; Epinephrine; | 1977 |
A comparative study of the aerosolized bronchodilators, isoproterenol, metaproterenol and terbutaline in asthma.
Topics: Adolescent; Adult; Aerosols; Aged; Asthma; Bronchodilator Agents; Clinical Trials as Topic; Female; | 1977 |
Terbutaline: an effective bronchodilator by inhalation.
Topics: Aerosols; Albuterol; Asthma; Bronchodilator Agents; Clinical Trials as Topic; Female; Humans; Male; | 1977 |
Comparison of terbutaline and salbutamol aerosols.
Topics: Adult; Aged; Albuterol; Asthma; Bronchitis; Chronic Disease; Clinical Trials as Topic; Female; Force | 1977 |
Terbutaline and ephedrine in asthmatic children.
Topics: Adolescent; Asthma; Blood Pressure; Child; Clinical Trials as Topic; Double-Blind Method; Drug Evalu | 1977 |
Terbutaline in the treatment of status asthmaticus.
Topics: Adolescent; Asthma; Blood Pressure; Carbon Dioxide; Child; Child, Preschool; Clinical Trials as Topi | 1977 |
Terbutaline in the treatment of acute asthma in childhood.
Topics: Acute Disease; Adolescent; Asthma; Blood Pressure; Child; Child, Preschool; Clinical Trials as Topic | 1977 |
Comparative bronchodilator responses to atropine and terbutaline in asthma and chronic bronchitis.
Topics: Airway Resistance; Asthma; Atropine; Bronchi; Bronchitis; Chronic Disease; Clinical Trials as Topic; | 1977 |
Bronchodilator effects of terbutaline and aminophylline alone and in combination in asthmatic patients.
Topics: Adolescent; Adult; Aged; Aminophylline; Asthma; Clinical Trials as Topic; Double-Blind Method; Drug | 1978 |
A comparison between an equimolar inhaled dose of ibuterol and terbutaline in asthmatics.
Topics: Adult; Aerosols; Aged; Asthma; Blood Pressure; Bronchial Spasm; Butyrates; Chemical Phenomena; Chemi | 1977 |
A controlled comparison of salbutamol and terbutaline inhaled by IPPV in asthmatic patients: a dose-response study.
Topics: Adult; Albuterol; Asthma; Bronchitis; Clinical Trials as Topic; Dose-Response Relationship, Drug; Do | 1977 |
A comparison between effects of aminophylline, proxyphylline and terbutaline in asthmatics.
Topics: Adult; Aminophylline; Asthma; Clinical Trials as Topic; Dose-Response Relationship, Drug; Drug Evalu | 1977 |
Stimulatory effect of beta-adrenergic drugs on mucociliary transport.
Topics: Asthma; Bronchi; Bronchitis; Chronic Disease; Cilia; Clinical Trials as Topic; Double-Blind Method; | 1977 |
A comparative evaluation of fenoterol and terbutaline in the treatment of asthma.
Topics: Adolescent; Adult; Asthma; Blood Pressure; Clinical Trials as Topic; Double-Blind Method; Drug Evalu | 1978 |
Effects of terbutaline aerosol in reversible airway obstruction.
Topics: Aerosols; Aged; Asthma; Bronchitis; Clinical Trials as Topic; Double-Blind Method; Drug Evaluation; | 1978 |
Comparison of terbutaline and salebutamol aerosols in patients with bronchial asthma.
Topics: Adolescent; Adult; Aerosols; Albuterol; Asthma; Clinical Trials as Topic; Female; Forced Expiratory | 1978 |
Terbutaline in asthmatic children: A dose-response study.
Topics: Adolescent; Asthma; Child; Child, Preschool; Clinical Trials as Topic; Dose-Response Relationship, D | 1978 |
Management of obstructive airways disease in pediatric patients with new beta2 sympathomimetic bronchodilators.
Topics: Asthma; Child; Child, Preschool; Clinical Trials as Topic; Double-Blind Method; Humans; Infant; Meta | 1978 |
Hexoprenaline and terbutaline administered by inhalation. A comparison between two beta2-adrenoreceptor agonists with respect to effect on bronchial obstruction, heart rate, blood pressure and muscle tremor.
Topics: Aerosols; Asthma; Blood Pressure; Clinical Trials as Topic; Double-Blind Method; Drug Evaluation; He | 1978 |
The efficacy of terbutaline and fenoterol aerosols on adult exercise-induced asthma [proceedings].
Topics: Adult; Aerosols; Asthma; Asthma, Exercise-Induced; Clinical Trials as Topic; Drug Evaluation; Ethano | 1979 |
Fenoterol in asthma.
Topics: Adult; Aged; Asthma; Clinical Trials as Topic; Double-Blind Method; Ethanolamines; Female; Fenoterol | 1979 |
Bronchodilator efficacy of a single oral dose of terbutaline sulphate--a double blind study.
Topics: Administration, Oral; Adult; Asthma; Clinical Trials as Topic; Double-Blind Method; Female; Humans; | 1978 |
Comparison of four weeks' treatment with fenoterol and terbutaline aerosols in adult asthmatics. A double-blind crossover study.
Topics: Adult; Aerosols; Asthma; Clinical Trials as Topic; Dose-Response Relationship, Drug; Double-Blind Me | 1979 |
Intravenous NAB 365 (clenbuterol) and terbutaline in exercise-induced bronchospasm (EIB).
Topics: Adolescent; Adult; Asthma; Asthma, Exercise-Induced; Blood Pressure; Clenbuterol; Ethanolamines; For | 1979 |
Safety and effectiveness of terbutaline in children with chronic asthma.
Topics: Administration, Oral; Adolescent; Asthma; Blood Pressure; Child; Double-Blind Method; Ephedrine; Fem | 1979 |
Terbutaline elixir in preschool children with chronic asthma.
Topics: Acute Disease; Asthma; Blood Pressure; Child; Child, Preschool; Chronic Disease; Dose-Response Relat | 1979 |
[Lung function studies with the bronchodilator terbutaline].
Topics: Adult; Aged; Airway Resistance; Asthma; Atropine; Clenbuterol; Drug Combinations; Ethylenediamines; | 1979 |
A tube spacer to improve inhalation of drugs from pressurised aerosols.
Topics: Aerosols; Aged; Asthma; Female; Humans; Male; Middle Aged; Respiratory Therapy; Terbutaline | 1979 |
Effects of oral terbutaline in children with bronchia asthma.
Topics: Administration, Oral; Airway Resistance; Asthma; Child; Dose-Response Relationship, Drug; Female; Fo | 1978 |
[The bronchospasmolytics salbutamol, fenoterol, terbutaline and reproterol. Their effects and side effects in asthmatics after inhalation with an electric nebulizer].
Topics: Adult; Aged; Albuterol; Asthma; Bronchodilator Agents; Female; Fenoterol; Humans; Hypoxia; Male; Met | 1978 |
Inhaled and oral bronchodilator therapy in exercise induced asthma.
Topics: Administration, Oral; Adolescent; Adult; Aerosols; Asthma; Child; Clinical Trials as Topic; Ethanola | 1975 |
Letter: Letter to the editor.
Topics: Asthma; Butyrates; Clinical Trials as Topic; Humans; Middle Aged; Peak Expiratory Flow Rate; Terbuta | 1976 |
[Comparison of oral terbutaline and aminophylline in asthmatic patients].
Topics: Administration, Oral; Adult; Aged; Aminophylline; Asthma; Clinical Trials as Topic; Drug Evaluation; | 1976 |
Acute effects of terbutaline and epinephrine on asthma. Double-blind crossover placebo study.
Topics: Adolescent; Adult; Asthma; Blood Pressure; Clinical Trials as Topic; Drug Evaluation; Electrocardiog | 1976 |
Tracheobronchial clearance in bronchial asthma: response to beta-adrenoceptor stimulation.
Topics: Adult; Asthma; Bronchi; Cilia; Clinical Trials as Topic; Female; Forced Expiratory Volume; Heart Rat | 1976 |
Bronchodilatory and circulatory effects of two doses of a beta2-agonist (terbutaline) inhaled with IPPB in patients with reversible airways obstruction.
Topics: Adult; Aged; Airway Obstruction; Asthma; Blood Circulation; Blood Pressure; Bronchi; Clinical Trials | 1976 |
Clinical evaluation of terbutaline and glyceryl guaiacolate in chronic obstructive lung disease.
Topics: Adult; Aged; Asthma; Bronchitis; Chronic Disease; Clinical Trials as Topic; Female; Guaifenesin; Hum | 1976 |
Asthma: ibuterol versus terbutaline inhalation.
Topics: Aerosols; Asthma; Humans; Terbutaline | 1977 |
Oral terbutaline sulfate--amelioration of exercise-induced bronchospasm.
Topics: Administration, Oral; Adult; Asthma; Bronchial Spasm; Forced Expiratory Volume; Humans; Maximal Mide | 1976 |
Studies of new sympathomimetic beta-receptor stimulating drugs in asthmatic patients. IV Acomparative trial of subcutaneous terbutaline (Bricanyl) and salbutamol (Ventolin).
Topics: Adolescent; Adult; Aged; Albuterol; Asthma; Child; Female; Heart Rate; Humans; Male; Middle Aged; Te | 1976 |
Cardiopulmonary effects of long-term bronchodilator administration.
Topics: Asthma; Blood Pressure; Bronchodilator Agents; Ephedrine; Forced Expiratory Volume; Heart Rate; Huma | 1976 |
Double-blind comparison of acute bronchial and cardiovascular effects of oral terbutaline and ephedrine.
Topics: Adolescent; Adult; Aged; Airway Resistance; Asthma; Blood Pressure; Bronchi; Cardiovascular System; | 1975 |
[Testing of the bronchodilator NAB 365 in a double blind trial author's transl].
Topics: Airway Resistance; Albuterol; Asthma; Bronchitis; Bronchodilator Agents; Carbon Dioxide; Clinical Tr | 1975 |
Objective and subjective comparisons of terbutaline and rimiterol bronchodilator aerosols.
Topics: Adult; Aerosols; Aged; Asthma; Bronchodilator Agents; Chronic Disease; Clinical Trials as Topic; Dru | 1975 |
Comparison between ibuterol hydrochloride and terbutaline in asthma.
Topics: Asthma; Blood Pressure; Bronchi; Butyrates; Clinical Trials as Topic; Dose-Response Relationship, Dr | 1976 |
The effect of terbutaline in exercise-induced asthma.
Topics: Adolescent; Adult; Asthma; Blood Pressure; Clinical Trials as Topic; Drug Evaluation; Female; Heart | 1976 |
A comparison of different intervals of administration of inhaled terbutaline in children with acute asthma.
Topics: Acute Disease; Administration, Inhalation; Adolescent; Asthma; Blood Pressure; Bronchi; Bronchoconst | 1992 |
Rapid onset of action of inhaled formoterol in asthmatic patients.
Topics: Administration, Inhalation; Adrenergic beta-Agonists; Adult; Aged; Asthma; Bronchodilator Agents; Do | 1992 |
Effects of budesonide and bambuterol on circadian variation of airway responsiveness and nocturnal symptoms of asthma.
Topics: Adolescent; Adrenergic beta-Agonists; Adult; Asthma; Bronchodilator Agents; Budesonide; Circadian Rh | 1992 |
Tolerance to the nonbronchodilator effects of inhaled beta 2-agonists in asthma.
Topics: Adenosine Monophosphate; Administration, Inhalation; Adrenergic beta-Agonists; Adult; Asthma; Bronch | 1992 |
Breath-actuated inhalers in chronic asthma: comparison of Diskhaler and Turbohaler for delivery of beta-agonists.
Topics: Administration, Inhalation; Adrenergic beta-Agonists; Adult; Aged; Albuterol; Asthma; Chronic Diseas | 1992 |
Bronchodilation and beta 2-selectivity of broxaterol in asthmatics: a crossover, single-blind, terbutaline- and placebo-controlled study.
Topics: Adrenergic beta-Agonists; Adult; Airway Resistance; Asthma; Blood Pressure; Bronchi; Bronchodilator | 1992 |
Pilot study to compare the bronchodilator and metabolic responses to terbutaline infusion in seven asthmatic subjects--are they correlated?
Topics: Adult; Asthma; Blood Glucose; Female; Humans; Infusions, Intravenous; Male; Middle Aged; Peak Expira | 1992 |
Increased inhaled bronchodilator vs increased inhaled corticosteroid in the control of moderate asthma.
Topics: Administration, Inhalation; Adult; Aerosols; Albuterol; Asthma; Beclomethasone; Bronchodilator Agent | 1992 |
Hypomagnesemia due to beta 2-agonist use in bronchial asthma.
Topics: Administration, Oral; Albuterol; Asthma; Humans; Injections, Subcutaneous; Magnesium; Potassium; Ter | 1992 |
Effect of inhaled formoterol versus terbutaline on respiratory function in moderate bronchial asthma.
Topics: Administration, Inhalation; Adult; Asthma; Bronchodilator Agents; Double-Blind Method; Ethanolamines | 1992 |
Pharmacokinetics and pharmacodynamics of bambuterol, a long-acting bronchodilator pro-drug of terbutaline, in young and elderly patients with asthma.
Topics: Adult; Aged; Asthma; Blood Pressure; Bronchodilator Agents; Cholinesterases; Female; Heart Rate; Hum | 1992 |
Long-term multicentre trial in chronic nonspecific lung disease: methodology and baseline assessment in adult patients. Dutch CNSLD Study Group.
Topics: Adult; Asthma; Beclomethasone; Bronchial Hyperreactivity; Double-Blind Method; Follow-Up Studies; Fo | 1992 |
New method of evaluating patient preference for different inhalation delivery systems.
Topics: Administration, Inhalation; Adult; Asthma; Bronchodilator Agents; Budesonide; Humans; Middle Aged; N | 1992 |
Effects, side effects and plasma concentrations of terbutaline in adult asthmatics after inhaling from a dry powder inhaler device at different inhalation flows and volumes.
Topics: Adult; Asthma; Female; Humans; Lung; Male; Nebulizers and Vaporizers; Powders; Terbutaline | 1992 |
Bronchodilator intake and plasma levels on admission for severe acute asthma.
Topics: Acute Disease; Administration, Inhalation; Adult; Aged; Albuterol; Asthma; Blood Pressure; Dose-Resp | 1992 |
A comparative study of the effects of an inhaled corticosteroid, budesonide, and a beta 2-agonist, terbutaline, on airway inflammation in newly diagnosed asthma: a randomized, double-blind, parallel-group controlled trial.
Topics: Administration, Inhalation; Adult; Asthma; Biopsy; Bronchi; Bronchitis; Bronchodilator Agents; Budes | 1992 |
Nebuhaler versus wet aerosol for domiciliary bronchodilator therapy. A multi-centre clinical comparison.
Topics: Adult; Aerosols; Airway Obstruction; Asthma; Child; Forced Expiratory Volume; Humans; Nebulizers and | 1992 |
Effect of terbutaline on mucociliary clearance in asthmatic and healthy subjects after inhalation from a pressurised inhaler and a dry powder inhaler.
Topics: Administration, Inhalation; Adult; Aerosols; Aged; Asthma; Double-Blind Method; Female; Forced Expir | 1991 |
Terbutaline powder in asthma exacerbations.
Topics: Administration, Inhalation; Adolescent; Asthma; Child; Humans; Terbutaline; Time Factors | 1991 |
Lifestyle changes in mild asthma during intermittent symptom-related use of terbutaline inhaled via 'Turbohaler'.
Topics: Activities of Daily Living; Administration, Inhalation; Adolescent; Adult; Aged; Asthma; Child; Chil | 1991 |
Unequal day-night terbutaline i.v. dosing in acute severe asthma: effect on nocturnal bronchial patency, heart rate, and arterial pressure.
Topics: Acute Disease; Adult; Analysis of Variance; Asthma; Blood Pressure; Bronchi; Circadian Rhythm; Drug | 1991 |
Dose of nebulized ipratropium bromide in acute severe asthma.
Topics: Acute Disease; Administration, Inhalation; Adult; Asthma; Double-Blind Method; Drug Administration S | 1991 |
Treatment of bronchial asthma with terbutaline inhaled by conespacer combined with positive expiratory pressure mask.
Topics: Adult; Aged; Asthma; Bronchodilator Agents; Equipment Design; Female; Forced Expiratory Volume; Huma | 1991 |
Budesonide and terbutaline or terbutaline alone in children with mild asthma: effects on bronchial hyperresponsiveness and diurnal variation in peak flow.
Topics: Administration, Inhalation; Adolescent; Asthma; Bronchial Provocation Tests; Bronchodilator Agents; | 1991 |
Effect of formoterol, a long-lasting beta 2-adrenoceptor agonist, against methacholine-induced bronchoconstriction.
Topics: Adrenergic beta-Agonists; Adult; Asthma; Blood Pressure; Bronchi; Double-Blind Method; Ethanolamines | 1990 |
Nebulized or intravenous beta 2 adrenoceptor agonist therapy in acute asthma?
Topics: Administration, Inhalation; Adrenergic beta-Agonists; Aerosols; Albuterol; Asthma; Clinical Trials a | 1990 |
Can a new beta 2-agonist reduce the mortality of asthma?
Topics: Administration, Oral; Adolescent; Adrenergic beta-Agonists; Adult; Aged; Airway Resistance; Albutero | 1990 |
Effects of a combined treatment theophylline and tulobuterol on nocturnal chronic asthma.
Topics: Adrenergic beta-Agonists; Adult; Aged; Asthma; Bronchodilator Agents; Double-Blind Method; Drug Admi | 1990 |
Prolonged treatment with oral and inhaled tulobuterol does not induce airways tachyphlaxis.
Topics: Administration, Inhalation; Administration, Oral; Adrenergic beta-Agonists; Airway Resistance; Asthm | 1990 |
Bronchodilator, cardiovascular, and hypokalaemic effects of fenoterol, salbutamol, and terbutaline in asthma.
Topics: Adolescent; Adult; Albuterol; Asthma; Bronchi; Bronchial Provocation Tests; Bronchodilator Agents; D | 1990 |
Bambuterol: a new long acting bronchodilating prodrug.
Topics: Administration, Oral; Adolescent; Adult; Aged; Asthma; Bronchi; Bronchodilator Agents; Circadian Rhy | 1991 |
Bricanyl Turbuhaler in the treatment of asthma: a six week multi-centre study carried out in Sweden, the United Kingdom, Denmark, Norway and Finland.
Topics: Administration, Inhalation; Adolescent; Adult; Aged; Asthma; Consumer Behavior; Europe; Female; Huma | 1991 |
Comparison of a beta 2-agonist, terbutaline, with an inhaled corticosteroid, budesonide, in newly detected asthma.
Topics: Adolescent; Adult; Asthma; Bronchial Provocation Tests; Bronchodilator Agents; Budesonide; Female; G | 1991 |
Exercise-induced asthma and the generation of neutrophil chemotactic activity.
Topics: Adult; Aerosols; Asthma; Asthma, Exercise-Induced; Budesonide; Chemotaxis, Leukocyte; Cromolyn Sodiu | 1990 |
Effects of sequential doses of parenteral terbutaline on plasma levels of potassium and related cardiopulmonary responses.
Topics: Adult; Asthma; Blood Glucose; Blood Pressure; Double-Blind Method; Drug Administration Schedule; Ele | 1990 |
The acceptability and efficacy of terbutaline given by metered-dose powder inhalation ('Bricanyl Turbohaler') in asthmatic hospital out-patients: a multi-centre study.
Topics: Administration, Inhalation; Adolescent; Adult; Aged; Asthma; Child; Consumer Behavior; Female; Force | 1990 |
Influence of inspiratory flow rate upon the effect of a Turbuhaler.
Topics: Adolescent; Asthma; Child; Child, Preschool; Double-Blind Method; Female; Humans; Inhalation; Male; | 1990 |
Inflammatory cells and eosinophilic activity in asthmatics investigated by bronchoalveolar lavage. The effects of antiasthmatic treatment with budesonide or terbutaline.
Topics: Adult; Asthma; Blood Proteins; Bronchoalveolar Lavage Fluid; Bronchodilator Agents; Budesonide; Eosi | 1990 |
The airways effects of inhaled chlorbutol in asthmatic subjects.
Topics: Adult; Asthma; Bronchial Provocation Tests; Bronchial Spasm; Chlorobutanol; Double-Blind Method; Fem | 1990 |
Nocturnal oxygen saturation and body movement in asthmatics treated with controlled-release preparations of theophylline or terbutaline.
Topics: Adult; Asthma; Delayed-Action Preparations; Double-Blind Method; Female; Humans; Male; Middle Aged; | 1990 |
Once-daily theophylline in the treatment of nocturnal asthma.
Topics: Adolescent; Adult; Aged; Asthma; Delayed-Action Preparations; Double-Blind Method; Drug Administrati | 1990 |
Comparison of Bricanyl Turbuhaler and Berotec dry powder inhaler.
Topics: Asthma; Child; Female; Fenoterol; Humans; Male; Nebulizers and Vaporizers; Peak Expiratory Flow Rate | 1990 |
Effects of dilevalol, a beta-adrenoceptor antagonist with intrinsic sympathetic activity in asthmatic patients.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Asthma; Atenolol; Double-Blind Method; Female; Forced Expi | 1989 |
Long-term oral therapy of asthma with terbutaline and theophylline, alone and combined.
Topics: Administration, Oral; Adolescent; Adult; Aged; Akathisia, Drug-Induced; Arrhythmias, Cardiac; Asthma | 1985 |
Equivalent inhibition by terbutaline of anti-human IgE skin responses in atopic and non-atopic subjects.
Topics: Adrenergic beta-Agonists; Adult; Antibodies, Anti-Idiotypic; Asthma; Depression, Chemical; Desensiti | 1985 |
Comparison of outpatient nebulized vs metered dose inhaler terbutaline in chronic airflow obstruction.
Topics: Administration, Inhalation; Aged; Ambulatory Care; Asthma; Dose-Response Relationship, Drug; Double- | 1989 |
Dose-effect relationship of terbutaline using a multi-dose powder inhalation system ('Turbuhaler') and salbutamol administered by powder inhalation ('Rotahaler') in asthmatics.
Topics: Administration, Inhalation; Adult; Albuterol; Asthma; Dose-Response Relationship, Drug; Forced Expir | 1989 |
Comparison of subcutaneous injections of terbutaline, salbutamol and adrenaline in acute asthmatic attacks in children.
Topics: Acute Disease; Adolescent; Albuterol; Asthma; Blood Pressure; Child; Child, Preschool; Epinephrine; | 1989 |
Nocturnal asthma: effect of treatment with oral sustained-release terbutaline, inhaled budesonide, and the two in combination.
Topics: Administration, Inhalation; Adolescent; Adult; Aged; Asthma; Budesonide; Circadian Rhythm; Clinical | 1989 |
Slow-release terbutaline and theophylline for the long-term therapy of children with asthma: a Latin square and factorial study of drug effects and interactions.
Topics: Adolescent; Analysis of Variance; Asthma; Child; Clinical Trials as Topic; Delayed-Action Preparatio | 1989 |
Management of acute bronchial asthma--intravenous terbutaline or aminophylline?
Topics: Aminophylline; Asthma; Clinical Trials as Topic; Humans; Infusions, Intravenous; Terbutaline | 1989 |
Comparative efficacy of terbutaline administered by Nebuhaler and by nebulizer in young children with acute asthma.
Topics: Acute Disease; Aerosols; Analysis of Variance; Asthma; Child; Child, Preschool; Clinical Trials as T | 1989 |
A double-blind comparison between a new multidose powder inhaler (Turbuhaler) and metered dose inhaler in children with asthma.
Topics: Adolescent; Asthma; Child; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Male; Mult | 1989 |
[Treatment of nocturnal bronchial asthma].
Topics: Adolescent; Adult; Asthma; Clinical Trials as Topic; Delayed-Action Preparations; Double-Blind Metho | 1989 |
Comparison between epinephrine and terbutaline injections in the acute management of asthma.
Topics: Asthma; Child; Child, Preschool; Epinephrine; Heart Rate; Humans; Infant; Injections; Respiration; R | 1989 |
A multiple dose powder inhaler (Turbuhaler) compared with a conventional aerosol. An acceptance study in asthmatics.
Topics: Adult; Aerosols; Aged; Asthma; Consumer Behavior; Equipment Design; Female; Humans; Lung; Male; Medi | 1989 |
Optimal inhalation technique with terbutaline Turbuhaler.
Topics: Administration, Inhalation; Adolescent; Asthma; Child; Double-Blind Method; Evaluation Studies as To | 1989 |
Duration of action of inhaled terbutaline at two different doses and of albuterol in protecting against bronchoconstriction induced by hyperventilation of dry cold air in asthmatic subjects.
Topics: Administration, Inhalation; Adult; Aged; Albuterol; Asthma; Bronchi; Child; Cold Temperature; Female | 1989 |
Comparison of a new multidose powder inhaler with a pressurized aerosol in children with asthma.
Topics: Administration, Inhalation; Adolescent; Aerosols; Asthma; Child; Dose-Response Relationship, Drug; F | 1989 |
Treatment of asthma in pre-school children with inhalation of terbutaline in Turbuhaler compared with Nebuhaler.
Topics: Asthma; Child, Preschool; Female; Humans; Male; Medical Records; Nebulizers and Vaporizers; Random A | 1989 |
Combination therapy of theophylline and terbutaline as sustained-release preparations in patients with asthmatic bronchitis.
Topics: Adult; Asthma; Cyclic AMP; Delayed-Action Preparations; Double-Blind Method; Drug Evaluation; Drug T | 1987 |
Controlled-release metoprolol compared with atenolol in asthmatic patients: interaction with terbutaline.
Topics: Adult; Aged; Asthma; Atenolol; Clinical Trials as Topic; Delayed-Action Preparations; Double-Blind M | 1988 |
Influence of terbutaline on natural killer cell activity.
Topics: Adolescent; Adult; Asthma; Cyclic AMP; Female; Humans; Killer Cells, Natural; Male; Middle Aged; Ter | 1988 |
Need for intravenous hydrocortisone in addition to oral prednisolone in patients admitted to hospital with severe asthma without ventilatory failure.
Topics: Acute Disease; Administration, Oral; Adolescent; Adult; Aerosols; Aminophylline; Asthma; Clinical Tr | 1986 |
Terbutaline slow-release tablets in children with asthma. A comparison with t.i.d. beta 2-agonist therapy.
Topics: Administration, Oral; Adolescent; Adrenergic beta-Agonists; Albuterol; Asthma; Child; Child, Prescho | 1986 |
Tulobuterol in childhood asthma: single dose ranging and repeated oral dose comparative studies.
Topics: Administration, Oral; Adolescent; Adrenergic beta-Agonists; Asthma; Child; Clinical Trials as Topic; | 1986 |
A comparative study on the ventilatory and haemodynamic effects of xamoterol and atenolol in asthmatic patients.
Topics: Adrenergic beta-Agonists; Adult; Asthma; Atenolol; Blood Pressure; Double-Blind Method; Forced Expir | 1986 |
Theophylline in maintenance treatment of chronic asthma: concentration-dependent additional effect to beta 2-agonist therapy.
Topics: Adrenergic beta-Agonists; Adult; Aged; Albuterol; Asthma; Chronic Disease; Clinical Trials as Topic; | 1987 |
Rebound increase in bronchial responsiveness after treatment with inhaled terbutaline.
Topics: Adolescent; Adult; Asthma; Bronchi; Bronchial Provocation Tests; Clinical Trials as Topic; Double-Bl | 1988 |
Increased theophylline clearance in asthmatic patients due to terbutaline.
Topics: Adult; Asthma; Delayed-Action Preparations; Drug Interactions; Female; Humans; Male; Middle Aged; Te | 1989 |
Aerosol bronchodilator delivery methods. Relative impact on pulmonary function and cost of respiratory care.
Topics: Aerosols; Asthma; Costs and Cost Analysis; Fees and Charges; Female; Hospital Bed Capacity, 100 to 2 | 1989 |
Procaterol and terbutaline in bronchial asthma. A double-blind, placebo-controlled, cross-over study.
Topics: Adolescent; Adult; Aged; Asthma; Clinical Trials as Topic; Double-Blind Method; Ethanolamines; Femal | 1985 |
Nebulization versus injection in ambulatory treatment of acute asthma: a comparative study.
Topics: Acute Disease; Aerosols; Asthma; Atropine Derivatives; Clinical Trials as Topic; Drug Therapy, Combi | 1988 |
Cumulative dose response relationship of terbutaline delivered by three different inhalers.
Topics: Adolescent; Aerosols; Asthma; Child; Clinical Trials as Topic; Dose-Response Relationship, Drug; Fem | 1988 |
Turbuhaler: a new device for dry powder terbutaline inhalation.
Topics: Administration, Inhalation; Adult; Asthma; Clinical Trials as Topic; Female; Humans; Male; Middle Ag | 1988 |
Bambuterol: clinical effects of three doses of bambuterol once daily in asthmatic patients.
Topics: Adult; Aged; Asthma; Bronchodilator Agents; Clinical Trials as Topic; Double-Blind Method; Drug Admi | 1988 |
Terbutaline sustained-release tablets in nocturnal asthma--a placebo-controlled comparison between a high and a low evening dose.
Topics: Adult; Asthma; Clinical Trials as Topic; Delayed-Action Preparations; Double-Blind Method; Humans; M | 1988 |
Bronchodilatory therapy with nebuhaler: how important is the delay between firing the dose and inhaling?
Topics: Administration, Inhalation; Asthma; Clinical Trials as Topic; Female; Forced Expiratory Volume; Huma | 1988 |
Long term treatment of severe asthma with subcutaneous terbutaline.
Topics: Adult; Asthma; Clinical Trials as Topic; Female; Humans; Infusion Pumps; Male; Middle Aged; Terbutal | 1988 |
Heat-labile neutrophil chemotactic activity in subjects with asthma after allergen inhalation: relation to the late asthmatic reaction and effects of asthma medication.
Topics: Adult; Allergens; Asthma; Budesonide; Chemotaxis, Leukocyte; Cromolyn Sodium; Double-Blind Method; F | 1987 |
Double-blind evaluation of nebulized cromolyn, terbutaline, and the combination for childhood asthma.
Topics: Asthma; Child; Cromolyn Sodium; Double-Blind Method; Drug Therapy, Combination; Female; Home Nursing | 1988 |
Nocturnal asthma: effects of slow-release terbutaline on spirometry and arterial blood-gases.
Topics: Asthma; Carbon Dioxide; Clinical Trials as Topic; Delayed-Action Preparations; Double-Blind Method; | 1988 |
Eosinophil granule proteins in serum after allergen challenge of asthmatic patients and the effects of anti-asthmatic medication.
Topics: Adult; Allergens; Asthma; Blood Proteins; Bronchodilator Agents; Budesonide; Cromolyn Sodium; Double | 1988 |
Nebuhaler technique.
Topics: Adolescent; Asthma; Child; Evaluation Studies as Topic; Female; Forced Expiratory Flow Rates; Humans | 1988 |
Open cross-over comparison of tulobuterol and fenoterol in asthmatic adult patients.
Topics: Adult; Albuterol; Asthma; Drug Evaluation; Fenoterol; Humans; Middle Aged; Random Allocation; Respir | 1988 |
A new multiple dose powder inhaler, (Turbuhaler), compared with a pressurized inhaler in a study of terbutaline in asthmatics.
Topics: Adult; Asthma; Female; Forced Expiratory Volume; Humans; Male; Middle Aged; Nebulizers and Vaporizer | 1988 |
Comparison of the effects of nebulized terbutaline with intravenous enprofylline in patients with acute asthma.
Topics: Acute Disease; Adolescent; Adult; Aged; Asthma; Bronchodilator Agents; Clinical Trials as Topic; Dou | 1988 |
Subcutaneous adrenaline versus terbutaline in the treatment of acute severe asthma.
Topics: Acute Disease; Adolescent; Adult; Asthma; Clinical Trials as Topic; Double-Blind Method; Epinephrine | 1988 |
Nocturnal asthma: slow-release terbutaline versus slow-release theophylline therapy.
Topics: Adult; Asthma; Clinical Trials as Topic; Delayed-Action Preparations; Double-Blind Method; Female; H | 1988 |
Intravenous versus nebulized terbutaline in patients with acute severe asthma; a double-blind randomized study.
Topics: Acute Disease; Administration, Inhalation; Asthma; Blood Pressure; Clinical Trials as Topic; Double- | 1987 |
Terbutaline by Nebuhaler in young children.
Topics: Age Factors; Asthma; Child; Child, Preschool; Clinical Trials as Topic; Double-Blind Method; Female; | 1986 |
Treatment of nocturnal asthma: the role of sustained-release theophylline and oral beta-2-mimetics.
Topics: Adult; Asthma; Circadian Rhythm; Clinical Trials as Topic; Delayed-Action Preparations; Double-Blind | 1987 |
Fenoterol is as effective as terbutaline in the pear-shaped spacer.
Topics: Adult; Aged; Asthma; Clinical Trials as Topic; Double-Blind Method; Fenoterol; Humans; Middle Aged; | 1987 |
Effect of sustained release terbutaline on symptoms and sleep quality in patients with nocturnal asthma.
Topics: Administration, Oral; Aged; Asthma; Clinical Trials as Topic; Delayed-Action Preparations; Double-Bl | 1987 |
Effect of terbutaline administered from metered dose inhaler (2 mg) and subcutaneously (0.25 mg) on tracheobronchial clearance in mild asthma.
Topics: Administration, Inhalation; Asthma; Bronchi; Clinical Trials as Topic; Double-Blind Method; Female; | 1987 |
Comparison between a new once-daily, bronchodilating drug, bambuterol, and terbutaline sustained-release, twice daily.
Topics: Adolescent; Adult; Aerosols; Asthma; Delayed-Action Preparations; Double-Blind Method; Drug Administ | 1988 |
A comparison of the clinical and bronchodilating effects of plain and slow-release tablets of terbutaline at steady state.
Topics: Administration, Oral; Adult; Asthma; Bronchi; Clinical Trials as Topic; Delayed-Action Preparations; | 1986 |
Bronchodilator activity of a new inhaled beta 2-adrenoceptor agonist, tulobuterol and its protective effect in exercise-induced asthma.
Topics: Adult; Albuterol; Asthma; Asthma, Exercise-Induced; Blood Pressure; Bronchodilator Agents; Clinical | 1986 |
Bambuterol: dose response study of a new terbutaline prodrug in asthma.
Topics: Adult; Aged; Asthma; Blood Pressure; Clinical Trials as Topic; Dose-Response Relationship, Drug; Dou | 1986 |
Effects of divided doses of a bronchodilator aerosol and the intervening time interval on the forced expiration.
Topics: Aerosols; Asthma; Clinical Trials as Topic; Drug Administration Schedule; Female; Forced Expiratory | 1986 |
Addition of terbutaline to optimal theophylline therapy. Double blind crossover study in asthmatic patients.
Topics: Administration, Intranasal; Administration, Oral; Adolescent; Adult; Aged; Asthma; Child; Clinical T | 1986 |
Simplification of inhalation therapy in asthmatic children. A comparison of two regimes.
Topics: Adolescent; Aerosols; Asthma; Budesonide; Child; Clinical Trials as Topic; Double-Blind Method; Fema | 1986 |
Sustained-release terbutaline in nocturnal asthma.
Topics: Adult; Aged; Asthma; Circadian Rhythm; Clinical Trials as Topic; Delayed-Action Preparations; Double | 1986 |
Comparison of two chamber devices in patients using a metered-dose inhaler with satisfactory technique.
Topics: Asthma; Bronchial Spasm; Clinical Trials as Topic; Female; Humans; Male; Middle Aged; Nebulizers and | 1986 |
Domiciliary comparison of terbutaline treatment by metered dose inhaler with and without conical spacer in severe and moderately severe chronic asthma.
Topics: Administration, Inhalation; Aerosols; Asthma; Bronchi; Clinical Trials as Topic; Dose-Response Relat | 1986 |
Effect of long-term treatment with inhaled corticosteroids and beta-agonists on the bronchial responsiveness in children with asthma.
Topics: Administration, Inhalation; Adolescent; Adrenal Cortex Hormones; Asthma; Bronchi; Budesonide; Child; | 1987 |
Additive bronchodilator effects of terbutaline and enprofylline in asthma.
Topics: Adult; Aged; Asthma; Blood Pressure; Bronchodilator Agents; Drug Synergism; Female; Forced Expirator | 1987 |
Terbutaline pressurised aerosol inhaled via a Nebuhaler--an effective alternative to subcutaneous adrenaline for treatment of acute severe asthma.
Topics: Acute Disease; Adolescent; Adult; Aerosols; Asthma; Double-Blind Method; Dyspnea; Epinephrine; Femal | 1987 |
[Bronchodilating effect of terbutaline inhaled with and without a tube spacer in asthmatic children].
Topics: Administration, Inhalation; Adolescent; Asthma; Child; Female; Forced Expiratory Volume; Humans; Mal | 1987 |
Airflows after inhalation of terbutaline sulphate aerosol from a 750-ml spacer for four weeks.
Topics: Adult; Aerosols; Aged; Asthma; Female; Forced Expiratory Volume; Humans; Male; Middle Aged; Peak Exp | 1986 |
A new inhalation technique for improved effect of aerosolized drugs in asthma. The shrug of the shoulder method.
Topics: Adult; Aerosols; Aged; Asthma; Female; Forced Expiratory Volume; Humans; Male; Middle Aged; Respirat | 1986 |
Sustained-release terbutaline vs sustained-release theophylline in young patients with asthma.
Topics: Adolescent; Aerosols; Asthma; Child; Delayed-Action Preparations; Double-Blind Method; Female; Human | 1986 |
Comparison of Nebuhaler and nebulizer treatment of acute severe asthma in children.
Topics: Acute Disease; Adolescent; Asthma; Child; Double-Blind Method; Female; Forced Expiratory Volume; Hum | 1986 |
Terbutaline slow-release tablets in children with bronchial asthma. Effect and pharmacokinetics compared with plain terbutaline tablets.
Topics: Adolescent; Asthma; Blood Pressure; Child; Delayed-Action Preparations; Drug Administration Schedule | 1986 |
[Paradoxal reaction in an asthma patient after inhalation of terbutaline].
Topics: Airway Obstruction; Asthma; Bronchial Spasm; Clinical Trials as Topic; Double-Blind Method; Humans; | 1985 |
Comparison of nebulized terbutaline and subcutaneous epinephrine in the treatment of acute asthma.
Topics: Acute Disease; Adolescent; Aerosols; Asthma; Child; Clinical Trials as Topic; Double-Blind Method; E | 1985 |
Treatment of acute bronchoconstriction in children with use of a tube spacer aerosol and a dry powder inhaler.
Topics: Adolescent; Aerosols; Albuterol; Asthma; Bronchodilator Agents; Child; Clinical Trials as Topic; Dou | 1985 |
Guaiphenesin and iodide.
Topics: Asthma; Clinical Trials as Topic; Double-Blind Method; Guaifenesin; Humans; Iodides; Lung Diseases; | 1985 |
Pear shaped spacer nebuhaler compared with nebulised solution for terbutaline administration in acute severe asthma.
Topics: Acute Disease; Adolescent; Adult; Aerosols; Aged; Asthma; Clinical Trials as Topic; Female; Forced E | 1985 |
Terbutaline depot tablets in childhood asthma. A double-blind controlled study.
Topics: Adolescent; Asthma; Child; Clinical Trials as Topic; Delayed-Action Preparations; Double-Blind Metho | 1985 |
Bambuterol: effects of a new anti-asthmatic drug.
Topics: Adult; Aged; Asthma; Bronchodilator Agents; Clinical Trials as Topic; Delayed-Action Preparations; D | 1985 |
The importance of a pause between the inhalation of two puffs of terbutaline from a pressurized aerosol with a tube spacer.
Topics: Adolescent; Aerosols; Asthma; Bronchi; Child; Dose-Response Relationship, Drug; Female; Forced Expir | 1986 |
Comparison of the acute cardiopulmonary effects of oral albuterol, metaproterenol, and terbutaline in asthmatics.
Topics: Adolescent; Adult; Albuterol; Asthma; Blood Pressure; Bronchodilator Agents; Double-Blind Method; Fe | 1985 |
Reduction of serum theophylline levels by terbutaline in children with asthma.
Topics: Asthma; Blood Pressure; Child; Chromatography, High Pressure Liquid; Delayed-Action Preparations; Do | 1985 |
[The Nebuhaler in the treatment of children with bronchial asthma: comparison of its efficacy with that of 2 other forms of administration].
Topics: Adolescent; Asthma; Child; Child, Preschool; Female; Humans; Male; Respiratory Therapy; Terbutaline | 1985 |
Optimal use of tube spacer aerosols in asthmatic children.
Topics: Adolescent; Aerosols; Asthma; Child; Female; Forced Expiratory Flow Rates; Humans; Inspiratory Capac | 1985 |
Changes in bronchial hyperreactivity induced by 4 weeks of treatment with antiasthmatic drugs in patients with allergic asthma: a comparison between budesonide and terbutaline.
Topics: Adolescent; Adult; Asthma; Bronchial Provocation Tests; Budesonide; Double-Blind Method; Eosinophils | 1985 |
Terbutaline by metered-dose inhaler: conventional inhaler versus tube spacer for children with asthma.
Topics: Aerosols; Asthma; Child; Double-Blind Method; Humans; Respiratory Function Tests; Respiratory Therap | 1985 |
[Pulmonary function tests on the bronchospasmolytic effects of the beta-2-adrenergics: salbutamol, terbutaline and NAB 365 (double placebo experiment)].
Topics: Adrenergic beta-Agonists; Airway Resistance; Albuterol; Alcohols; Amines; Asthma; Bronchitis; Chlori | 1974 |
The role of oral bronchodilator therapy as shown by a comparison between salbutamol and terbutaline.
Topics: Administration, Oral; Adult; Airway Obstruction; Albuterol; Asthma; Blood Pressure; Clinical Trials | 1973 |
Clinical comparison of intramuscular terbutaline and subcutaneous adrenaline in bronchial asthma.
Topics: Asthma; Blood Pressure; Bronchodilator Agents; Clinical Trials as Topic; Epinephrine; Heart Rate; Hu | 1974 |
Bronchodilator effects of terbutaline and epinephrine in obstructive lung disease.
Topics: Adult; Aged; Airway Resistance; Asthma; Blood Pressure; Bronchitis; Bronchodilator Agents; Chronic D | 1974 |
[Use of a new bronchiolytic preparation terbutaline in the treatment of patients with obstructive lung diseases].
Topics: Adult; Asthma; Bronchitis; Chronic Disease; Clinical Trials as Topic; Drug Evaluation; Female; Human | 1974 |
A comparison of salbutamol and terbutaline aerosols in bronchial asthma.
Topics: Adult; Aerosols; Aged; Albuterol; Asthma; Blood Pressure; Heart Rate; Humans; Middle Aged; Spirometr | 1973 |
A comparison of the effects of subcutaneous orciprenaline, salbutamol and terbutaline in asthmatic children.
Topics: Adolescent; Albuterol; Asthma; Blood Pressure; Child; Child, Preschool; Dose-Response Relationship, | 1974 |
338 other studies available for terbutaline and Asthma
| Article | Year |
|---|---|
The β2-adrenergic receptor agonist terbutaline upregulates T helper-17 cells in a protein kinase A-dependent manner.
Topics: Adrenergic Agonists; Asthma; Autoimmune Diseases; CD28 Antigens; Cyclic AMP-Dependent Protein Kinase | 2023 |
As-needed β agonist-inhaled corticosteroid in mild asthma.
Topics: Adrenal Cortex Hormones; Adult; Asthma; Budesonide; Formoterol Fumarate; Humans; Terbutaline | 2019 |
Global Initiative for Asthma 2019 Guidelines: New Changes to the Treatment of Mild Asthmatics 12 Years and Older.
Topics: Administration, Inhalation; Adolescent; Adrenal Cortex Hormones; Adrenergic beta-2 Receptor Agonists | 2020 |
Novel lipid-polymer hybrid nanoparticles incorporated in thermosensitive in situ gel for intranasal delivery of terbutaline sulphate.
Topics: Administration, Intranasal; Animals; Asthma; Chitosan; Drug Delivery Systems; Kinetics; Lipids; Male | 2020 |
The Impact of Terbutaline as Adjuvant Therapy in the Treatment of Severe Asthma in the Pediatric Emergency Department.
Topics: Asthma; Bronchodilator Agents; Child; Emergency Service, Hospital; Humans; Retrospective Studies; Te | 2022 |
Sustained release of tulobuterol from graphene oxide laden hydrogel to manage asthma.
Topics: Animals; Asthma; Delayed-Action Preparations; Graphite; Hydrogels; Rabbits; Rats; Rats, Sprague-Dawl | 2021 |
Living with severe asthma since childhood.
Topics: Adult; Anti-Asthmatic Agents; Asthma; Bronchodilator Agents; Female; Humans; Terbutaline; United Kin | 2021 |
Licorice-induced apparent mineralocorticoid excess compounded by excessive use of terbutaline and high water intake.
Topics: Aldosterone; Asthma; Bronchodilator Agents; Diagnosis, Differential; Glycyrrhiza; Humans; Hypertensi | 2018 |
As-needed budesonide-formoterol better controlled mild asthma vs terbutaline, but maintenance budesonide was better.
Topics: Administration, Inhalation; Asthma; Budesonide; Formoterol Fumarate; Humans; Terbutaline | 2018 |
Effect of terbutaline combined with budesonide in treatment of bronchial asthma and rehabilitation nursing.
Topics: Administration, Inhalation; Adult; Asthma; Bronchodilator Agents; Budesonide; Female; Glucocorticoid | 2018 |
[Hyperlactatemia induced by inhaled β2 agonists: An underrecognized side effect. Report of two cases].
Topics: Administration, Inhalation; Adrenergic beta-2 Receptor Agonists; Aged; Asthma; Female; Humans; Hyper | 2019 |
Real-life effectiveness of inhaler device switch from dry powder inhalers to pressurized metred-dose inhalers in patients with asthma treated with ICS/LABA.
Topics: Administration, Inhalation; Adolescent; Adrenal Cortex Hormones; Adrenergic beta-2 Receptor Agonists | 2019 |
Astragalus membranaceus improves therapeutic efficacy of asthmatic children by regulating the balance of Treg/Th17 cells.
Topics: Animals; Asthma; Astragalus propinquus; Budesonide; Cells, Cultured; Child; Child, Preschool; Cytoki | 2019 |
Differential effects of inhaled R- and S-terbutaline in ovalbumin-induced asthmatic mice.
Topics: Administration, Inhalation; Animals; Asthma; Bronchoalveolar Lavage Fluid; Bronchoconstriction; Bron | 2019 |
Cough variant and cough-predominant asthma are major causes of persistent cough: a multicenter study in Japan.
Topics: Adrenergic beta-Agonists; Adult; Asthma; Cough; Female; Humans; Japan; Male; Middle Aged; Prospectiv | 2013 |
[Lactic acidosis after inhaled beta-2 agonists: about 2 cases].
Topics: Acidosis, Lactic; Administration, Inhalation; Adrenergic beta-2 Receptor Agonists; Albuterol; Asthma | 2014 |
Early administration of terbutaline in severe pediatric asthma may reduce incidence of acute respiratory failure.
Topics: Adrenergic beta-2 Receptor Agonists; Asthma; Bronchodilator Agents; Child; Female; Humans; Incidence | 2014 |
Intravenous β agonists and severe pediatric asthma exacerbation: time for a closer look at terbutaline?
Topics: Adrenergic beta-2 Receptor Agonists; Asthma; Bronchodilator Agents; Female; Humans; Male; Respirator | 2014 |
Transient occult cardiotoxicity in children receiving continuous beta-agonist therapy.
Topics: Acute Disease; Administration, Inhalation; Adolescent; Adrenergic beta-Agonists; Albuterol; Asthma; | 2014 |
Continuous terbutaline infusion in severe asthma in adults: a retrospective study of long-term efficacy and safety.
Topics: Adult; Anti-Asthmatic Agents; Asthma; Female; Forced Expiratory Volume; Humans; Infusions, Intraveno | 2014 |
Regular treatment for moderate asthma: guidelines hold true.
Topics: Anti-Asthmatic Agents; Asthma; Bronchodilator Agents; Budesonide, Formoterol Fumarate Drug Combinati | 2015 |
[Acute asthma in emergency room. Primum non nocere!].
Topics: Acute Disease; Adrenergic beta-2 Receptor Agonists; Asthma; Bronchodilator Agents; Drug Therapy, Com | 2015 |
Safety of Terbutaline for Treatment of Acute Severe Pediatric Asthma.
Topics: Adolescent; Asthma; Blood Pressure; Bronchodilator Agents; Child; Child, Preschool; Female; Heart Ra | 2018 |
Terbutaline: level the playing field for inhaled β
Topics: Administration, Inhalation; Adrenergic beta-2 Receptor Agonists; Asthma; Athletes; Bronchoconstricti | 2017 |
Effect of gender on theophylline clearance in the asthmatic acute phase in Japanese pediatric patients.
Topics: Acute Disease; Aging; Anti-Asthmatic Agents; Anti-Inflammatory Agents; Asthma; Child; Child, Prescho | 2009 |
Sequential evaluation of serum monocyte chemotactic protein 1 among asymptomatic state and acute exacerbation and remission of asthma in children.
Topics: Acute Disease; Adolescent; Androstadienes; Asthma; Bronchodilator Agents; Chemokine CCL2; Child; Chi | 2009 |
Tulobuterol patch maintains diaphragm muscle contractility for over twenty-four hours in a mouse model of sepsis.
Topics: Administration, Cutaneous; Adrenergic beta-Agonists; Animals; Asthma; Diaphragm; Disease Models, Ani | 2009 |
Comparative study of skin permeation profiles between brand and generic tulobuterol patches.
Topics: Animals; Asthma; Bronchodilator Agents; Disease Models, Animal; Drugs, Generic; Female; Patents as T | 2010 |
Polymorphisms of the β2-adrenergic receptor correlated to nocturnal asthma and the response of terbutaline nebulizer.
Topics: Adrenergic beta-2 Receptor Agonists; Analysis of Variance; Asthma; Chi-Square Distribution; Child; F | 2011 |
Lactic acidosis as a complication of β-adrenergic aerosols.
Topics: Acidosis, Lactic; Adrenergic beta-2 Receptor Agonists; Aerosols; Asthma; Bronchodilator Agents; Emer | 2012 |
Effects of beta-arrestin 2 on cytokine production of CD4+ T lymphocytes of mice with allergic asthma.
Topics: Adrenergic beta-2 Receptor Agonists; Animals; Arrestins; Asthma; beta-Arrestin 2; beta-Arrestins; Bl | 2011 |
Asthma phenotypes: consistency of classification using induced sputum.
Topics: Adult; Anti-Asthmatic Agents; Asthma; Budesonide; Eosinophilia; Eosinophils; Female; Humans; Leukocy | 2012 |
Anti-asthmatic agents alleviate pulmonary edema by upregulating AQP1 and AQP5 expression in the lungs of mice with OVA-induced asthma.
Topics: Ambroxol; Animals; Anti-Asthmatic Agents; Aquaporin 1; Aquaporin 5; Asthma; Dexamethasone; Lung; Mic | 2012 |
Treating acute asthma--salbutamol may not always be the right answer.
Topics: Acidosis, Lactic; Acute Disease; Administration, Inhalation; Adrenergic beta-2 Receptor Agonists; Al | 2012 |
[Questionnaire survey on the change of asthmatic response, adverse events and product usability due to drug switching between name-brand and generic tulobuterol tapes].
Topics: Aged; Asthma; Child, Preschool; Drug Substitution; Drug Utilization; Drugs, Generic; Female; Humans; | 2012 |
Urine and serum concentrations of inhaled and oral terbutaline.
Topics: Administration, Inhalation; Administration, Oral; Adolescent; Adult; Asthma; Bronchodilator Agents; | 2012 |
Detection of wheezing during maximal forced exhalation in patients with obstructed airways.
Topics: Analysis of Variance; Anthropometry; Asthma; Bronchodilator Agents; Case-Control Studies; Female; Fo | 2002 |
Clinical-pharmacokinetic aspects of prolonged effect duration as illustrated by beta2-agonists.
Topics: Academic Dissertations as Topic; Administration, Inhalation; Administration, Oral; Adrenergic beta-A | 2002 |
Effects of sustained-release tulobuterol on asthma control and beta-adrenoceptor function.
Topics: Adrenergic beta-Agonists; Adult; Analysis of Variance; Animals; Asthma; Delayed-Action Preparations; | 2002 |
[Cramp fever?].
Topics: Anti-Inflammatory Agents; Asthma; Breast Neoplasms; Bronchodilator Agents; Budesonide; Diagnosis, Di | 2003 |
Effects of a nitro compound patch on neuropathy in Churg-Strauss syndrome.
Topics: Adrenergic beta-Agonists; Asthma; Churg-Strauss Syndrome; Cyclophosphamide; Drug Hypersensitivity; F | 2003 |
The use of inhaled and related respiratory medications in Christchurch rest homes.
Topics: Administration, Inhalation; Adrenal Cortex Hormones; Adrenergic beta-Agonists; Aged; Aged, 80 and ov | 2003 |
The effect of montelukast on exhaled nitric oxide and lung function in asthmatic children 2 to 5 years old.
Topics: Acetates; Airway Resistance; Anti-Asthmatic Agents; Asthma; Breath Tests; Bronchodilator Agents; Chi | 2005 |
[Connubial contact dermatitis to an inhaled corticosteroid].
Topics: Administration, Inhalation; Angioedema; Asthma; Bronchodilator Agents; Budesonide; Child, Preschool; | 2005 |
Alteration of the circadian rhythm in peak expiratory flow of nocturnal asthma following nighttime transdermal beta2-adrenoceptor agonist tulobuterol chronotherapy.
Topics: Administration, Cutaneous; Adrenergic beta-Agonists; Adult; Anti-Asthmatic Agents; Asthma; Biologica | 2005 |
Lupine inhalation induced asthma in a child.
Topics: Administration, Inhalation; Albuterol; Anti-Inflammatory Agents; Asthma; Bronchodilator Agents; Chil | 2005 |
Safety of intravenous terbutaline in acute severe asthma: a retrospective study.
Topics: Adolescent; Asthma; Blood Pressure; Bronchodilator Agents; Child; Child, Preschool; Cohort Studies; | 2005 |
[The management of bronchial asthma during pregnancy--Hungarian experiences].
Topics: Administration, Inhalation; Adult; Albuterol; Anti-Asthmatic Agents; Asthma; Birth Weight; Budesonid | 2005 |
Treatment strategy for asthma: one for all and all for one?
Topics: Adrenergic beta-Agonists; Asthma; Bronchodilator Agents; Budesonide; Drug Combinations; Drug Therapy | 2006 |
[Terbutaline-induced lactic acidosis during an acute asthma attack].
Topics: Acidosis, Lactic; Acute Disease; Adult; Asthma; Bronchodilator Agents; Female; Humans; Terbutaline | 2006 |
Irrational combination of montelukast and bambuterol for management of childhood asthma.
Topics: Acetates; Asthma; Bronchodilator Agents; Child; Cyclopropanes; Drug Approval; Drug Combinations; Dru | 2006 |
[How to make easier the treatment of asthma].
Topics: Administration, Inhalation; Adolescent; Adrenal Cortex Hormones; Aerosols; Albuterol; Androstadienes | 2006 |
[Metabolic acidosis in a context of acute severe asthma].
Topics: Acidosis, Lactic; Acute Disease; Albuterol; Asthma; Bronchodilator Agents; Female; Humans; Middle Ag | 2007 |
Salbutamol, terbutaline and pirbuterol allergy in an asthmatic patient.
Topics: Adult; Aerosols; Albuterol; Asthma; Bronchoconstriction; Bronchodilator Agents; Drug Hypersensitivit | 2007 |
[Oxygen driven inhalation of budesonide and terbutaline to control acute episode of asthma].
Topics: Acute Disease; Administration, Inhalation; Adolescent; Asthma; Budesonide; Child; Child, Preschool; | 2007 |
Paradoxical asthma hazard of short-acting beta2-agonists.
Topics: Adrenergic beta-2 Receptor Agonists; Adrenergic beta-Agonists; Albuterol; Asthma; Bronchoconstrictio | 2008 |
Mechanical and biochemical alterations in guinea-pig tracheae caused by sensitisation.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Airway Resistance; Animals; Asthma; Bronchi; Cyclic AMP; Dihydr | 1984 |
Combined vs. sequential vs. single-entity therapy.
Topics: Albuterol; Aminophylline; Asthma; Beclomethasone; Drug Therapy, Combination; Ephedrine; Epinephrine; | 1981 |
A pressurized beta 2-agonist aerosol used in the treatment of children with asthma caused by bronchial provocation.
Topics: Adolescent; Adrenergic beta-Agonists; Aerosols; Asthma; Bronchial Provocation Tests; Child; Child, P | 1982 |
Successful treatment of terbutaline-induced bronchospasm with orciprenaline sulfate.
Topics: Asthma; Bronchial Spasm; Female; Humans; Metaproterenol; Middle Aged; Terbutaline | 1982 |
Methylxanthines in asthma.
Topics: Adrenergic beta-Agonists; Asthma; Humans; Kinetics; Phosphodiesterase Inhibitors; Terbutaline; Theop | 1983 |
Airway hyperreactivity. Clinical treatment with drugs.
Topics: Acetylcholine; Adrenal Cortex Hormones; Adrenergic beta-Agonists; Asthma; Bronchial Provocation Test | 1983 |
Beta-adrenergic drugs in the management of asthma in athletes.
Topics: Adrenergic beta-Agonists; Albuterol; Asthma; Asthma, Exercise-Induced; Dose-Response Relationship, D | 1984 |
Effects of beta 1-adrenoceptor stimulation and blockade studied in asthmatic airways.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Asthma; Humans; Metoprolol; Practolol; Prenal | 1984 |
Studies on beta 2-sympathicomimetic-induced desensitization at the level of pulmonary adrenoceptors.
Topics: Adrenergic beta-Agonists; Animals; Asthma; Desensitization, Immunologic; Dihydroalprenolol; Lung; Ra | 1984 |
[Airway hypersensitivity and beta-adrenergic blockade in asthmatic patients, with special reference to insulin response to beta-stimulant].
Topics: Adolescent; Adrenergic beta-Agonists; Adult; Aged; Airway Resistance; Asthma; Blood Glucose; Cyclic | 1983 |
Treating the elderly asthmatic patient.
Topics: Adrenal Cortex Hormones; Adrenergic alpha-Agonists; Adrenergic beta-Agonists; Aged; Asthma; Bronchod | 1984 |
[Combined use of talinolol and beta adrenergic stimulants in status asthmaticus. Report on 3 patients].
Topics: Adrenergic beta-Antagonists; Adult; Aged; Aminophylline; Asthma; Drug Therapy, Combination; Electroc | 1984 |
Correlation between terbutaline serum levels, c-AMP plasma levels and FEV1 in normals and asthmatics after subcutaneous administration.
Topics: Adult; Asthma; Cyclic AMP; Forced Expiratory Volume; Humans; Injections, Subcutaneous; Kinetics; Mid | 1980 |
Partial beta-adrenergic receptor blockade in experimental bronchial asthma.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Asthma; Cyclic AMP; Disease Models, Animal; Guinea Pig | 1980 |
Subsensitization of beta-adrenoceptors in airways and lymphocytes of healthy and asthmatic subjects.
Topics: Adolescent; Adult; Asthma; Bronchial Provocation Tests; Desensitization, Immunologic; Dose-Response | 1982 |
Clinical implications of drug-induced desensitization of the beta receptor after continuous oral use of terbutaline.
Topics: Adult; Asthma; Cyclic AMP; Humans; Leukocytes; Lung Volume Measurements; Middle Aged; Receptors, Adr | 1982 |
Reversal of human lymphocyte beta-adrenoceptor desensitization by glucocorticoids.
Topics: Adult; Asthma; Humans; Lymphocytes; Methylprednisolone; Receptors, Adrenergic; Receptors, Adrenergic | 1982 |
The bronchial tree and the beta-adrenergic system.
Topics: Asthma; Bronchi; Bronchial Provocation Tests; Cyclic AMP; Humans; Receptors, Adrenergic; Receptors, | 1982 |
Tremor measurement in asthma. II. Changes after terbutaline administration suggesting beta-adrenergic blockade.
Topics: Administration, Oral; Adult; Asthma; Cyclic AMP; Humans; Injections, Subcutaneous; Male; Middle Aged | 1982 |
Selective subsensitization of beta-adrenergic receptors in central airways of asthmatics and normal subjects during long-term therapy with inhaled salbutamol.
Topics: Administration, Intranasal; Adult; Albuterol; Asthma; Bronchial Spasm; Bronchodilator Agents; Dose-R | 1982 |
Timed effects of an oral adrenergic bronchodilator on pulmonary function and measurements of plasma and leukocyte cyclic AMP: divergence in duration of drug action and development of tolerance.
Topics: Administration, Oral; Adult; Asthma; Bronchodilator Agents; Cyclic AMP; Delayed-Action Preparations; | 1983 |
Changes in the beta-adrenergic system in bronchial asthma induced by terbutaline.
Topics: Adult; Asthma; Cyclic AMP; Female; Forced Expiratory Volume; Humans; Lymphocytes; Male; Propranolol; | 1983 |
Measurement of beta-adrenergic receptors on lymphocytes in normal subjects and asthmatics in relation to beta-adrenergic hyperglycaemic response and bronchial responsiveness.
Topics: Acetylcholine; Adolescent; Adrenal Cortex Hormones; Adult; Aged; Airway Resistance; Asthma; Bronchia | 1983 |
Airway hyperreactivity. Cholinergic and adrenergic receptors.
Topics: Albuterol; Asthma; Bronchi; Humans; Parasympathetic Nervous System; Practolol; Prenalterol; Receptor | 1983 |
Comparison of beta 2-adrenoceptor stimulation in bronchial and skeletal muscle in experimental and clinical studies.
Topics: Albuterol; Animals; Asthma; Bronchi; Cats; Guinea Pigs; Histamine; Humans; Muscle, Smooth; Muscles; | 1984 |
Ventilatory and haemodynamic effects of beta 1-selective and beta 2-selective stimulation in asthmatic patients.
Topics: Asthma; Blood Pressure; Heart Rate; Humans; Metoprolol; Practolol; Prenalterol; Receptors, Adrenergi | 1984 |
Changes in the beta-adrenergic system due to beta-adrenergic therapy: clinical consequences.
Topics: Adenine Nucleotides; Asthma; Desensitization, Immunologic; Forced Expiratory Volume; Humans; In Vitr | 1984 |
[Rational asthma drug therapy].
Topics: Aminophylline; Anti-Bacterial Agents; Asthma; Bronchial Spasm; Cromolyn Sodium; Desensitization, Imm | 1983 |
[Modification of exercise-induced airway obstruction using a combination of 2 drugs].
Topics: Adult; Asthma; Asthma, Exercise-Induced; Cromolyn Sodium; Drug Therapy, Combination; Heart Function | 1983 |
Potential limitations of a conical spacer device in severe asthma.
Topics: Adult; Aerosols; Asthma; Equipment Failure; Female; Humans; Terbutaline | 1984 |
Conical spacer devices in severe asthma.
Topics: Asthma; Humans; Respiratory Therapy; Terbutaline | 1984 |
[Treatment of status asthmaticus. Prospective evaluation of a protocol combining aminophylline and terbutaline (44 cases)].
Topics: Adult; Aged; Aminophylline; Arrhythmias, Cardiac; Asthma; Bronchial Spasm; Carbon Dioxide; Drug Eval | 1984 |
Drug intake and plasma concentrations in acute asthma.
Topics: Acute Disease; Administration, Oral; Aerosols; Albuterol; Asthma; Ethanolamines; Female; Fenoterol; | 1984 |
The efficacy of drug delivery by a pear-shaped spacer and metered dose inhaler.
Topics: Adult; Aerosols; Aged; Asthma; Chronic Disease; Dose-Response Relationship, Drug; Female; Forced Exp | 1984 |
Home nebulizers in severe chronic asthma.
Topics: Adult; Aerosols; Aged; Asthma; Chronic Disease; Circadian Rhythm; Dose-Response Relationship, Drug; | 1984 |
[Recommendations for the treatment of status asthmaticus in private and clinical practice].
Topics: Acute Disease; Aerosols; Anti-Bacterial Agents; Asthma; Fluid Therapy; Hospitalization; Humans; Hypn | 1983 |
Anti-asthmatic effects and drug tolerance of selective beta 2-adrenergic stimulants in guinea-pigs.
Topics: Albuterol; Animals; Asthma; Disease Models, Animal; Drug Tolerance; Ethanolamines; Fenoterol; Guinea | 1983 |
Oral administration of terbutaline in asthmatic patients.
Topics: Administration, Oral; Asthma; Biotransformation; Blood Pressure; Forced Expiratory Volume; Half-Life | 1984 |
Kinetics of terbutaline in asthmatic children.
Topics: Administration, Oral; Asthma; Biological Availability; Child; Female; Half-Life; Humans; Injections, | 1984 |
Oral terbutaline in chronic childhood asthma; effects related to plasma concentrations.
Topics: Asthma; Child; Dose-Response Relationship, Drug; Forced Expiratory Volume; Humans; Peak Expiratory F | 1984 |
Simultaneous treatment with terbutaline and theophylline.
Topics: Adult; Aged; Asthma; Blood Pressure; Double-Blind Method; Drug Therapy, Combination; Female; Forced | 1984 |
Comparison of the effects of a new anticholinergic drug (AA 28-263, Sandoz) and terbutaline in a dose-response study in endogenous asthmatics.
Topics: Adult; Aerosols; Airway Resistance; Asthma; Blood Pressure; Dibenzothiepins; Dose-Response Relations | 1984 |
Plasma terbutaline levels in asthma.
Topics: Asthma; Child; Dose-Response Relationship, Drug; Humans; Terbutaline | 1983 |
Comparison of a 750 ml spacer and a nebulizer in domiciliary treatment of severe chronic asthma with terbutaline.
Topics: Adult; Aerosols; Asthma; Double-Blind Method; Female; Humans; Male; Middle Aged; Peak Expiratory Flo | 1983 |
Comparison of three techniques of inhalation on the airway response to terbutaline.
Topics: Adult; Aerosols; Asthma; Bronchi; Dose-Response Relationship, Drug; Female; Forced Expiratory Volume | 1983 |
Hypothyroidism with coexistent asthma: problems in management.
Topics: Acute Disease; Asthma; Delayed-Action Preparations; Drug Therapy, Combination; Humans; Hypothyroidis | 1984 |
Dose, plasma concentration, and effect of oral terbutaline in long-term treatment of childhood asthma.
Topics: Administration, Oral; Adolescent; Asthma; Child; Dose-Response Relationship, Drug; Female; Heart Rat | 1984 |
[Bronchodilator effect of terbutaline (Bricanyl) in bronchial asthma patients].
Topics: Asthma; Bronchial Spasm; Drug Evaluation; Female; Humans; Male; Tablets; Terbutaline; Time Factors | 1984 |
Evaluation of immediate- and late-response inhibition of a new beta-agonist, KWD 2131, compared with terbutaline and DSCG.
Topics: Asthma; Bronchial Provocation Tests; Cromolyn Sodium; Drug Evaluation; Humans; Lung Volume Measureme | 1981 |
Terbutaline aerosol given through pear spacer in acute severe asthma.
Topics: Aerosols; Asthma; Child; Humans; Terbutaline | 1982 |
Terbutaline aerosol given through poor spacer in acute severe asthma.
Topics: Asthma; Humans; Prescription Fees; Terbutaline; United Kingdom | 1982 |
Influence of different extension-actuator tubes on the bronchodilation effect of a terbutaline sulfate aerosol.
Topics: Administration, Oral; Adult; Aerosol Propellants; Aged; Asthma; Bronchi; Female; Forced Expiratory V | 1983 |
Plasma terbutaline levels in asthma.
Topics: Asthma; Child; Female; Humans; Kinetics; Male; Peak Expiratory Flow Rate; Terbutaline | 1983 |
Nasal inhalation as a cause of inefficient pulmonal aerosol inhalation technique in children.
Topics: Administration, Intranasal; Adolescent; Aerosols; Aging; Asthma; Child; Child, Preschool; Female; Fo | 1983 |
Comparison of nebulized terbutaline (TERB) and subcutaneous epinephrine (EPI) in the treatment of acute asthma.
Topics: Acute Disease; Adolescent; Adult; Aerosols; Asthma; Blood Pressure; Epinephrine; Female; Humans; Inj | 1983 |
Pretreatment of exercise-induced asthma with terbutaline administered from pressurized aerosols and nebulizers.
Topics: Aerosols; Asthma; Asthma, Exercise-Induced; Humans; Pressure; Respiratory Therapy; Terbutaline | 1982 |
Pharmacokinetic studies with inhaled drugs.
Topics: Asthma; Humans; Isoproterenol; Kinetics; Respiratory Therapy; Terbutaline | 1982 |
The importance of particle size in response to inhaled bronchodilators.
Topics: Adolescent; Adult; Asthma; Bronchodilator Agents; Child; Humans; Middle Aged; Particle Size; Respira | 1982 |
[Obstructive airway diseases in children].
Topics: Abscess; Adult; Asthma; Child; Child, Preschool; Cystic Fibrosis; Foreign-Body Reaction; Humans; Inh | 1982 |
Cerebral ischemia associated with parenteral terbutaline use in pregnant migraine patients.
Topics: Adult; Asthma; Female; Humans; Injections, Subcutaneous; Ischemic Attack, Transient; Migraine Disord | 1982 |
High-dose inhaled terbutaline in the management of chronic severe asthma: comparison of wet nebulisation and tube-spacer delivery.
Topics: Aerosols; Aged; Asthma; Female; Humans; Male; Middle Aged; Respiratory Therapy; Terbutaline | 1982 |
Assessment of optimum dose of inhaled terbutaline in patients with chronic asthma: the use of simple, cumulative dose-response curves.
Topics: Aged; Asthma; Chronic Disease; Dose-Response Relationship, Drug; Female; Humans; Male; Middle Aged; | 1982 |
Separate and combined use of terbutaline and theophylline in asthmatics. Effects related to plasma levels.
Topics: Adult; Aged; Asthma; Dose-Response Relationship, Drug; Drug Interactions; Female; Forced Expiratory | 1982 |
[Sympathomimetic drugs in the treatment of childhood asthma].
Topics: Administration, Oral; Aerosols; Asthma; Child; Child, Preschool; Epinephrine; Humans; Injections, Su | 1982 |
Seizures in a patient receiving terbutaline.
Topics: Asthma; Child; Female; Humans; Seizures; Terbutaline | 1982 |
Bricanyl (terbutaline) treatment in obstructive bronchitis and asthma of childhood.
Topics: Asthma; Bronchitis; Chemical Phenomena; Chemistry; Child; Child, Preschool; Humans; Infant; Pulmonar | 1981 |
Pharmacokinetics of terbutaline, a beta 2-sympathomimetic, in healthy volunteers and asthmatic patients.
Topics: Administration, Oral; Adult; Asthma; Biological Availability; Humans; Injections, Subcutaneous; Kine | 1982 |
Adrenergic compounds and corticosteroids.
Topics: Administration, Oral; Adrenal Cortex Hormones; Aerosols; Albuterol; Asthma; Beclomethasone; Bronchod | 1981 |
Asthma induced by dust from urea-formaldehyde foam insulating material.
Topics: Asthma; Bronchial Provocation Tests; Construction Materials; Dust; Female; Formaldehyde; Humans; Mid | 1981 |
Inhalation of terbutaline spray through an extended mouthpiece: effect on central and peripheral airways.
Topics: Adult; Aerosols; Aged; Airway Resistance; Asthma; Female; Humans; Lung; Lung Volume Measurements; Ma | 1980 |
Bladder electromyography: response to electric stimulation and to terbutaline.
Topics: Asthma; Electric Stimulation; Electromyography; Humans; Male; Muscle Contraction; Pressure; Spinal C | 1981 |
Adrenaline and terbutaline in treatment of acute asthmatic attacks on children.
Topics: Acute Disease; Adolescent; Asthma; Blood Pressure; Child; Epinephrine; Female; Heart Rate; Humans; M | 1981 |
Terbutaline aerosol in the long-term treatment of asthmatic children.
Topics: Aerosols; Asthma; Child; Chronic Disease; Female; Humans; Male; Pulse; Respiratory Function Tests; T | 1981 |
Nonparametric analysis of response curves.
Topics: Adult; Animals; Asthma; Behavior, Animal; Blood Glucose; Child; Ephedrine; Humans; Obesity; Peak Exp | 1980 |
[Fenoterol in the diagnosis and treatment of reversible bronchospasm].
Topics: Adult; Albuterol; Asthma; Bronchial Spasm; Ethanolamines; Female; Fenoterol; Humans; Lung Diseases, | 1981 |
[Bronchial asthma and exacerbated chronic obstructive bronchitis].
Topics: Aged; Aminophylline; Anti-Bacterial Agents; Asthma; Bronchitis; Digoxin; Diuretics; Emergencies; Exp | 1981 |
Effect of theophylline and terbutaline on immediate skin tests.
Topics: Administration, Oral; Asthma; Humans; Hypersensitivity, Immediate; Skin Tests; Surveys and Questionn | 1980 |
Airways reactivity and the need for a simple test.
Topics: Asthma; Bronchial Provocation Tests; Humans; Lung Diseases, Obstructive; Terbutaline | 1980 |
Use of a special inhaler attachment in asthmatic children.
Topics: Aerosols; Asthma; Child; Female; Humans; Male; Respiratory Therapy; Terbutaline | 1980 |
Site and duration of bronchodilation in asthmatic patients after oral administration of terbutaline.
Topics: Adult; Asthma; Bronchi; Double-Blind Method; Female; Humans; Lung; Male; Placebos; Pulmonary Ventila | 1981 |
Emergency treatment of asthma.
Topics: Albuterol; Asthma; Bronchodilator Agents; Emergencies; Humans; Terbutaline | 1995 |
Pharmacokinetics and pharmacodynamics of the tulobuterol patch, HN-078, in childhood asthma.
Topics: Administration, Cutaneous; Adult; Aged; Asthma; Blood Pressure; Child; Female; Humans; Male; Respira | 1995 |
Identical efficacy of terbutaline multidose dry powder inhaler prior to and after 4 weeks of use by asthmatic patients.
Topics: Adolescent; Adult; Aged; Asthma; Dose-Response Relationship, Drug; Female; Humans; Male; Middle Aged | 1995 |
Effect of inhaled terbutaline on platelet activity in bronchial asthma.
Topics: Adult; Asthma; Blood Platelets; Bronchial Spasm; Female; Humans; Immunoglobulin E; Lung Volume Measu | 1994 |
Platelet-derived growth factor-beta mRNA in human alveolar macrophages in vivo in asthma.
Topics: Adult; Aerosols; Albuterol; Asthma; Beclomethasone; Blotting, Northern; Bronchodilator Agents; Budes | 1994 |
Patient compliance with inhaled medication: does combining beta-agonists with corticosteroids improve compliance?
Topics: Administration, Inhalation; Albuterol; Asthma; Bronchodilator Agents; Budesonide; Drug Therapy, Comb | 1994 |
Sex differences in hypokalaemic and electrocardiographic effects of inhaled terbutaline.
Topics: Administration, Inhalation; Asthma; Electrocardiography; Female; Fenoterol; Humans; Hypokalemia; Mal | 1993 |
Rhabdomyolysis following life-threatening acute asthma attack.
Topics: Acute Disease; Adult; Aminophylline; Asthma; Humans; Male; Rhabdomyolysis; Terbutaline | 1993 |
Paradoxical bronchoconstriction with nebulized albuterol but not with terbutaline.
Topics: Adult; Aerosols; Albuterol; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Bronchoc | 1993 |
Effect of glucocorticosteroid treatment on beta-adrenoceptor subtype function in adipocytes from patients with asthma.
Topics: Administration, Oral; Adult; Asthma; Cells, Cultured; Clonidine; Dobutamine; Dose-Response Relations | 1993 |
Sublingual terbutalin in bronchial asthma.
Topics: Acute Disease; Administration, Sublingual; Asthma; Child, Preschool; Humans; Infant; Terbutaline | 1993 |
[Efficacy and tolerance of terbutaline and budesonide administered via a pressurized aerosol inhaler or a Turbohaler in asthmatic patients].
Topics: Administration, Inhalation; Administration, Topical; Adult; Aged; Anti-Inflammatory Agents; Asthma; | 1993 |
How do patients with either asthma or COPD perceive acute bronchodilation?
Topics: Asthma; Bronchi; Dyspnea; Female; Humans; Linear Models; Lung Diseases, Obstructive; Male; Middle Ag | 1993 |
Atopic status in patients with brittle and non-brittle asthma: a case-control study.
Topics: Animals; Asthma; Case-Control Studies; Cats; Dogs; Female; Humans; Hypersensitivity, Immediate; Immu | 1995 |
Treat patients who have nocturnal asthma with anti-inflammatory drugs first.
Topics: Administration, Topical; Anti-Inflammatory Agents; Asthma; Bronchodilator Agents; Budesonide; Circad | 1996 |
Measurement of lung function in awake 2-4-year-old asthmatic children during methacholine challenge and acute asthma: a comparison of the impulse oscillation technique, the interrupter technique, and transcutaneous measurement of oxygen versus whole-body
Topics: Acute Disease; Airway Resistance; Asthma; Blood Gas Monitoring, Transcutaneous; Bronchial Provocatio | 1996 |
[Effect of inhaled corticosteroids on serum eosinophil cationic protein and sIL-2R levels in asthmatics pulmonary hypertension].
Topics: Administration, Inhalation; Adrenergic beta-Agonists; Adult; Anti-Asthmatic Agents; Asthma; Beclomet | 1995 |
Skeletal muscle magnesium and potassium in asthmatics treated with oral beta 2-agonists.
Topics: Administration, Oral; Adrenergic beta-Agonists; Albuterol; Asthma; Biopsy, Needle; Blood Chemical An | 1996 |
'Functional relaxation' reduces acute airway obstruction in asthmatics as effectively as inhaled terbutaline.
Topics: Adult; Aged; Aged, 80 and over; Airway Obstruction; Analysis of Variance; Asthma; Bronchodilator Age | 1996 |
Gas chromatographic-mass spectrometric determination of beta 2-agonists in postmortem blood: application in forensic medicine.
Topics: Adrenergic beta-Agonists; Albuterol; Asthma; Autopsy; Calibration; Fenoterol; Forensic Medicine; Gas | 1996 |
Disturbing asthma statistics reflect suboptimal management.
Topics: Adrenergic beta-Agonists; Anti-Asthmatic Agents; Anti-Inflammatory Agents; Asthma; Budesonide; Human | 1997 |
[Acute theophylline intoxication as differential diagnosis of pneumothorax in an asthma patient].
Topics: Administration, Oral; Asthma; Bronchodilator Agents; Diagnosis, Differential; Dose-Response Relation | 1997 |
Repeatability of methacholine challenges in 2- to 4-year-old children with asthma, using a new technique for quantitative delivery of aerosol.
Topics: Aerosols; Asthma; Bronchial Provocation Tests; Bronchoconstrictor Agents; Child, Preschool; Female; | 1997 |
[Effect of the beta-2 mimetic drug terbutaline of growth hormone secretion in prepubertal asthmatic children].
Topics: Adolescent; Adrenergic beta-Agonists; Asthma; Child; Child, Preschool; Circadian Rhythm; Female; Hum | 1997 |
MDI for acute asthma in children.
Topics: Acute Disease; Administration, Inhalation; Adolescent; Adrenergic beta-Agonists; Albuterol; Asthma; | 1998 |
Inhalation devices in childhood asthma.
Topics: Administration, Inhalation; Adrenergic beta-Agonists; Albuterol; Anti-Asthmatic Agents; Asthma; Bron | 1998 |
Effects of theophylline on lymphocyte phosphodiesterase activity.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adult; Age Factors; Aminophylline; Asthma; Bronchodilator Agent | 1998 |
Can oral beta2 agonists cause heart failure?
Topics: Administration, Oral; Adrenergic beta-Agonists; Aged; Albuterol; Asthma; Bronchodilator Agents; Coho | 1998 |
Clinical efficacy and safety of Turbuhaler as compared to pressurized MDIs-beta 2-agonists.
Topics: Aged; Albuterol; Asthma; Chlorofluorocarbons; Equipment Design; Humans; Middle Aged; Nebulizers and | 1994 |
Experience of an emergency mobile asthma treatment programme.
Topics: Adolescent; Adult; Age Distribution; Aged; Aged, 80 and over; Albuterol; Ambulances; Asthma; Broncho | 1997 |
Postmortem stability and interpretation of beta 2-agonist concentrations.
Topics: Adrenergic beta-Agonists; Albuterol; Asthma; Drug Stability; Fenoterol; Humans; Postmortem Changes; | 1999 |
Analysis of tracheal sounds during forced exhalation in asthma patients and normal subjects: bronchodilator response effect.
Topics: Adolescent; Adult; Asthma; Bronchodilator Agents; Female; Forced Expiratory Volume; Humans; Male; Mi | 1999 |
Bambuterol: new preparation. Poorly demonstrated efficacy.
Topics: Adult; Asthma; Bronchodilator Agents; Clinical Trials as Topic; Humans; Terbutaline; Treatment Outco | 1999 |
Difficult asthma.
Topics: Asthma; Bronchodilator Agents; Clinical Trials as Topic; Humans; Infusions, Parenteral; Injections, | 2000 |
Beta-adrenoceptor agonists in bronchial asthma: role of k+-channel opening in mediating their bronchodilator effects.
Topics: Adrenergic beta-1 Receptor Antagonists; Adrenergic beta-2 Receptor Antagonists; Adrenergic beta-Anta | 1993 |
The use of newer asthma and allergy medications during pregnancy. The American College of Obstetricians and Gynecologists (ACOG) and The American College of Allergy, Asthma and Immunology (ACAAI).
Topics: Abnormalities, Drug-Induced; Acetates; Administration, Inhalation; Administration, Intranasal; Admin | 2000 |
Cardiac toxicity of intravenous terbutaline for the treatment of severe asthma in children: a prospective assessment.
Topics: Adrenergic beta-Agonists; Asthma; Child; Child, Preschool; Creatine; Creatine Kinase; Female; Heart; | 2000 |
[Effect of a patch formulation of tulobuterol on cough scores and PEF in patients with cough variant asthma].
Topics: Adrenergic beta-Agonists; Adult; Asthma; Bronchodilator Agents; Cough; Drug Evaluation; Female; Huma | 2000 |
Clinical characteristics of asthmatic patients prescribed various beta-agonist metered-dose inhalers at Yamagata University Hospital.
Topics: Administration, Inhalation; Adolescent; Adrenergic beta-Agonists; Adult; Aged; Albuterol; Asthma; Ch | 2001 |
Age- and gender-specific asthma death rates in patients taking long-acting beta2-agonists: prescription event monitoring pharmacosurveillance studies.
Topics: Adrenergic beta-Agonists; Adult; Age Distribution; Aged; Aged, 80 and over; Albuterol; Asthma; Bronc | 2001 |
On-demand relief treatment for asthma.
Topics: Adrenergic beta-Agonists; Asthma; Bronchodilator Agents; Budesonide; Dose-Response Relationship, Dru | 2001 |
On-demand relief treatment for asthma.
Topics: Administration, Inhalation; Adrenergic beta-Agonists; Asthma; Bronchodilator Agents; Budesonide; Dos | 2001 |
An advanced and detailed in vitro validation procedure for the radiolabeling of carrier-free terbutaline sulphate dry powder.
Topics: Administration, Inhalation; Aerosols; Asthma; Bias; Bronchodilator Agents; Dose-Response Relationshi | 2001 |
Subcutaneous terbutaline in children with chronic severe asthma.
Topics: Adolescent; Adrenergic beta-Agonists; Asthma; Child; Chronic Disease; Female; Humans; Injections, Su | 2002 |
[Use of beta-adrenergic drugs in pediatric therapy].
Topics: Adrenergic beta-Agonists; Age Factors; Albuterol; Asthma; Child; Dyspnea; Humans; Isoproterenol; Met | 1976 |
[Comparative study of the effectiveness of beta-adrenergic stimulatin drugs].
Topics: Adrenergic beta-Agonists; Albuterol; Asthma; Bronchitis; Bronchodilator Agents; Drug Evaluation; For | 1976 |
Rapid, shallow breathing after Ascaris suum antigen inhalation: role of vagus nerves.
Topics: Animals; Antigens; Ascaris; Asthma; Carbon Dioxide; Cold Temperature; Disease Models, Animal; Dogs; | 1977 |
[Comparative clinical data on the bronchodilating effect of some selective beta-2 stimulating drugs].
Topics: Adrenergic beta-Agonists; Albuterol; Asthma; Bronchodilator Agents; Child; Female; Forced Expiratory | 1977 |
Decreased beta-adrenergic receptors on polymorphonuclear leukocytes after adrenergic therapy.
Topics: Adrenergic beta-Agonists; Alprenolol; Asthma; Humans; In Vitro Techniques; Neutrophils; Receptors, A | 1978 |
Blood eosinophil leucocyte and eosinophil cationic protein. In vivo study of the influence of beta-2-adrenergic drugs and steroid medication.
Topics: Adrenal Cortex Hormones; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Albuterol; Asthma; B | 1978 |
Desensitization of the beta-adrenergic receptor on leucocytes after long-term oral use of a beta-sympathicomimetic; its effect on the beta-adrenergic blockade hypothesis of Szentivanyi.
Topics: Adrenergic beta-Antagonists; Asthma; Cyclic AMP; Desensitization, Immunologic; Dose-Response Relatio | 1979 |
Rational management of bronchial asthma.
Topics: Asthma; Beclomethasone; Cromolyn Sodium; Humans; Metaproterenol; Sympathomimetics; Terbutaline; Theo | 1978 |
The preventive treatment of asthma.
Topics: Aerosols; Asthma; Beclomethasone; Cromolyn Sodium; Humans; Metaproterenol; Sympathomimetics; Terbuta | 1979 |
Prophylactic drugs in the management of childhood asthma.
Topics: Adolescent; Aerosols; Asthma; Beclomethasone; Child; Child, Preschool; Cromolyn Sodium; Female; Huma | 1979 |
Drugs other than corticosteroids for the treatment of asthma.
Topics: Adrenal Cortex Hormones; Adult; Asthma; Child; Cromolyn Sodium; Humans; Infant; Parasympathomimetics | 1979 |
Advances in the pharmacologic management of asthma.
Topics: Asthma; Beclomethasone; Bronchodilator Agents; Cromolyn Sodium; Humans; Terbutaline; Theophylline | 1979 |
[Effect of cromoglycate and terbutaline on exertion-produced bronchial spasm in asthmatic children].
Topics: Adolescent; Asthma; Asthma, Exercise-Induced; Bronchi; Child; Cromolyn Sodium; Female; Humans; Male; | 1979 |
[Pharmacological protection against bronchospasm in bronchial asthma].
Topics: Adolescent; Adult; Aminophylline; Amitriptyline; Asthma; Bronchial Spasm; Bronchodilator Agents; Cro | 1978 |
Lack of bronchial beta adrenoceptor resistance in asthmatics during long-term treatment with terbutaline.
Topics: Adult; Asthma; Blood Pressure; Bronchi; Bronchial Spasm; Dose-Response Relationship, Drug; Drug Resi | 1977 |
Subsensitivity of beta responses during therapy with a long-acting beta-2 preparation.
Topics: Asthma; Blood Glucose; Bronchitis; Cyclic AMP; Drug Tolerance; Eosinophils; Humans; Lactates; Middle | 1977 |
[Mechanisms of action of glucocorticoids in the treatment of asthma. Comparative effects of glucocorticods via the general route and beclomethasone dipropionate via aerial route on plasma levels of cyclic AMP].
Topics: Adult; Aerosols; Aged; Asthma; Beclomethasone; Child; Cyclic AMP; Female; Humans; Hydrocortisone; In | 1977 |
Drug-induced changes of adenylate cyclase activity in cells from asthmatic and nonasthmatic subjects.
Topics: Adenylyl Cyclases; Adult; Asthma; Child; Cyclic AMP; Desensitization, Immunologic; Female; Humans; I | 1977 |
A comparison of beta adrenergic function in asthma and chronic bronchitis.
Topics: Adult; Asthma; Blood Pressure; Bronchitis; Chronic Disease; Creatinine; Cyclic AMP; Forced Expirator | 1977 |
Therapeutic considerations in status asthmaticus.
Topics: Adrenal Cortex Hormones; Adult; Asthma; Bicarbonates; Epinephrine; Female; Humans; Male; Respiration | 1977 |
[Plasmatic AMPc and GMPc changes in asthmatic patients induced by beta stimulation or blockade and methylcholine (author's transl)].
Topics: Adolescent; Asthma; Child; Cyclic AMP; Cyclic GMP; Humans; Maximal Expiratory Flow Rate; Propranolol | 1978 |
Annals of allergy.
Topics: Adrenergic beta-Agonists; Aerosols; Albuterol; Asthma; Epinephrine; Fenoterol; Hexoprenaline; Isopro | 1975 |
Effect of beta-adrenoreceptor stimulants on exercise-induced asthma.
Topics: Adrenergic beta-Agonists; Airway Obstruction; Albuterol; Asthma; Child; Epinephrine; Humans; Isoetha | 1975 |
Broncho-and cardioselective beta-receptor active drugs in the treatment of asthmatic patients. Clinical studies of effects and side effects of terbutaline, practolol and metoprolol.
Topics: Administration, Oral; Asthma; Bronchodilator Agents; Dose-Response Relationship, Drug; Drug Evaluati | 1977 |
Comparison of infused and inhaled terbutaline in patients with asthma.
Topics: Aerosols; Asthma; Drug Evaluation; Humans; Injections, Intravenous; Terbutaline; Tremor | 1977 |
Dose of terbutaline respirator solution in children with asthma.
Topics: Adolescent; Asthma; Child; Forced Expiratory Volume; Humans; Respiratory Function Tests; Solutions; | 1979 |
Aerosolized terbutaline in asthmatics. Comparison of dosage strength, schedule, and method of administration.
Topics: Adolescent; Adult; Aerosols; Asthma; Dose-Response Relationship, Drug; Drug Administration Schedule; | 1979 |
Intravenous therapy with terbutaline.
Topics: Adult; Arrhythmias, Cardiac; Asthma; Drug Evaluation; Female; Heart; Humans; Infusions, Parenteral; | 1979 |
[Bronchial asthma in childhood].
Topics: Aminophylline; Asthma; Bronchi; Child; Desensitization, Immunologic; Humans; Immunoglobulin E; Predn | 1979 |
Management of the child with asthma.
Topics: Adrenal Cortex Hormones; Asthma; Bronchodilator Agents; Child; Food Hypersensitivity; Humans; Immuno | 1979 |
Imaging sites of airway obstruction and measuring functional responses to bronchodilator treatment in asthma.
Topics: Adolescent; Adult; Aerosols; Airway Obstruction; Asthma; Humans; Injections, Subcutaneous; Lung; Mid | 1979 |
Terbutaline and terbutaline combined with theophylline in asthmatics.
Topics: Administration, Oral; Aerosols; Asthma; Drug Evaluation; Drug Therapy, Combination; Humans; Injectio | 1979 |
A comparison of the bronchodilator efficacy of oral salbutamol and terbutaline.
Topics: Adult; Albuterol; Asthma; Female; Humans; Male; Pulmonary Ventilation; Terbutaline | 1979 |
[Terbutaline sulfate: effect of the oral, aerosol and intramuscular administration on the reversible bronchospasm of asthmatic bronchitis].
Topics: Adult; Aged; Asthma; Bronchial Spasm; Female; Humans; Male; Middle Aged; Terbutaline | 1979 |
[Management of severe asthma in childhood (author's transl)].
Topics: Acetylcysteine; Age Factors; Airway Obstruction; Albuterol; Aminophylline; Asthma; Bromhexine; Child | 1977 |
Terbutaline and muscular symptoms.
Topics: Asthma; Humans; Muscle Cramp; Terbutaline | 1978 |
Management of severe acute asthma.
Topics: Asthma; Epinephrine; Humans; Injections, Subcutaneous; Terbutaline | 1978 |
The treatment of asthma.
Topics: Adult; Aminophylline; Asthma; Bronchodilator Agents; Humans; Terbutaline; Theophylline | 1978 |
[Long-term effect and tolerance of broncholytics].
Topics: Adult; Aerosols; Aged; Albuterol; Asthma; Drug Resistance; Drug Tolerance; Fenoterol; Hexoprenaline; | 1978 |
[Use of sympathomimetics in the treatment of asthma].
Topics: Albuterol; Asthma; Bronchodilator Agents; Ephedrine; Epinephrine; Humans; Isoproterenol; Metaprotere | 1978 |
Management of severe acute asthma.
Topics: Acute Disease; Asthma; Drug Evaluation; Epinephrine; Humans; Terbutaline | 1978 |
Terbutaline for asthmatic children.
Topics: Asthma; Child; Humans; Terbutaline; United States; United States Food and Drug Administration | 1978 |
[Bronchodilators in babies with wheezy bronchitis (author's transl)].
Topics: Asthma; Bronchiolitis, Viral; Bronchitis; Complement Fixation Tests; Female; Humans; Immunoglobulin | 1978 |
Terbutaline sulphate nebulizer solution: a dose-response study.
Topics: Asthma; Dose-Response Relationship, Drug; Forced Expiratory Volume; Heart Rate; Humans; Terbutaline; | 1978 |
[Effect of subcutaneously injected terbutaline in provoked bronchial obstruction within the scope of inhalative testing of allergens].
Topics: Adolescent; Airway Resistance; Allergens; Asthma; Bronchi; Child; Humans; Injections, Subcutaneous; | 1977 |
Call it asthma, or why obstetrics is better in Sweden.
Topics: Asthma; Female; Humans; Obstetric Labor, Premature; Obstetrics; Pregnancy; Sweden; Terbutaline; Unit | 1977 |
[Reduction of nitroblue tetrazolium and the dyeing of peroxidase in patients with allergic bronchial asthma: influence of adrenergic beta-2 stimulants].
Topics: Adolescent; Adult; Asthma; Female; Humans; Leukocyte Count; Leukocytes; Male; Nitroblue Tetrazolium; | 1977 |
A long-term study of low-dose aerosolized terbutaline sulfate.
Topics: Adult; Aerosols; Airway Obstruction; Asthma; Blood Pressure; Female; Forced Expiratory Volume; Heart | 1976 |
Peripheral plasma determinations of prostaglandin E in asthmatics.
Topics: Adult; Aged; Asthma; Female; Humans; Male; Middle Aged; Prostaglandins E; Terbutaline | 1976 |
The mechanism of rapid, shallow breathing after inhaling histamine aerosol in exercising dogs.
Topics: Aerosols; Airway Resistance; Animals; Asthma; Atropine; Blood Gas Analysis; Dogs; Dose-Response Rela | 1976 |
Evaluation of terbutaline therapy in asthmatic children.
Topics: Administration, Oral; Adolescent; Asthma; Child; Female; Forced Expiratory Volume; Hemodynamics; Hum | 1976 |
Studies of new sympathomimetic beta-receptor stimulating drugs in asthmatic patients. III. A comparative trial of subcutaneous terbutaline and trimetoquinol.
Topics: Adolescent; Adult; Asthma; Czechoslovakia; History of Medicine; Humans; Injections, Subcutaneous; Is | 1975 |
Bronchodilatory and circulatory effects of inhaling increasing doses of an anti-cholinergic drug, ipratropium bromide (SCH 1000).
Topics: Adult; Aerosols; Aged; Asthma; Atropine; Blood Pressure; Bronchitis; Bronchodilator Agents; Drug Com | 1975 |
Evaluation of skeletal muscle tremor due to bronchodilator agents.
Topics: Adult; Asthma; Blood Pressure; Bronchitis; Chronic Disease; Female; Heart Rate; Humans; Isoprotereno | 1975 |
Terbutaline for asthma.
Topics: Administration, Oral; Asthma; Bronchi; Humans; Muscle, Smooth; Terbutaline | 1975 |
Effects of practolol in combination with terbutaline in the treatment of hypertension and arrhythmias in asthmatic patients.
Topics: Adult; Aged; Arrhythmias, Cardiac; Asthma; Blood Pressure; Chronic Disease; Drug Therapy, Combinatio | 1975 |
[Comparison between bronchodilator activity of terbutaline and orciprenaline in bronchial asthma].
Topics: Asthma; Humans; Male; Metaproterenol; Middle Aged; Terbutaline | 1975 |
Letter: Ibuterol hydrochloride and terbutaline in asthma.
Topics: Asthma; Butyrates; Dose-Response Relationship, Drug; Humans; Terbutaline | 1976 |
Development of "resistance" in beta-adrenergic receptors of asthmatic patients.
Topics: Administration, Oral; Adult; Aged; Asthma; Bronchi; Chronic Disease; Dose-Response Relationship, Dru | 1976 |
[Our experience in the treatment of bronchial asthma and asthmatic bronchitis with salbutamol].
Topics: Adolescent; Adult; Aged; Albuterol; Asthma; Bronchitis; Child; Drug Evaluation; Female; Humans; Isop | 1976 |
An account of the treatment of five chronic asthmatic patients.
Topics: Adult; Asthma; Chronic Disease; Female; Humans; Indoramin; Middle Aged; Tachyphylaxis; Terbutaline | 1976 |
Comparison of infused and inhaled terbutaline in patients with asthma.
Topics: Adult; Aerosols; Asthma; Blood Pressure; Dose-Response Relationship, Drug; Female; Heart Rate; Human | 1976 |
Influence of beta-adrenergic receptor function during terbutaline treatment on allergen sensitivity and bronchodilator response to terbutaline in asthmatic subjects.
Topics: Adult; Allergens; Asthma; Bronchial Provocation Tests; Bronchoconstriction; Catecholamines; Humans; | 1992 |
In vivo and in vitro beta 2-adrenergic receptor responsiveness in young and elderly asthmatics.
Topics: Adult; Age Factors; Aged; Asthma; Blood Chemical Analysis; Blood Pressure; Female; Heart Rate; Human | 1992 |
Continuous subcutaneous infusion of beta 2-agonists in infantile asthma.
Topics: Adrenergic beta-Agonists; Albuterol; Asthma; Feasibility Studies; Humans; Infant; Infusion Pumps; In | 1992 |
Perceived effect on shortness of breath of an acute inhalation of saline or terbutaline: variability and sensitivity of a visual analogue scale in patients with asthma or COPD.
Topics: Asthma; Dyspnea; Female; Forced Expiratory Volume; Humans; Lung Diseases, Obstructive; Male; Middle | 1992 |
Terbutaline sulphate Turbuhaler in severe acute asthma.
Topics: Adolescent; Asthma; Child; Child, Preschool; Humans; Nebulizers and Vaporizers; Terbutaline | 1992 |
Effects of a constant dose rate of terbutaline on circadian peak expiratory flow, heart rate and systolic arterial pressure in patients with asthma exacerbation.
Topics: Adult; Analysis of Variance; Asthma; Blood Pressure; Circadian Rhythm; Drug Administration Schedule; | 1992 |
Interpretation of bronchodilator response in patients with obstructive airways disease. The Dutch Chronic Non-Specific Lung Disease (CNSLD) Study Group.
Topics: Adolescent; Adult; Asthma; Bronchi; Forced Expiratory Volume; Humans; Lung; Lung Diseases, Obstructi | 1992 |
Response to nebulized ipratropium bromide and terbutaline in acute severe asthma.
Topics: Acute Disease; Administration, Inhalation; Adult; Aged; Asthma; Drug Therapy, Combination; Female; H | 1992 |
Effects of treatment on airway inflammation and thickening of basement membrane reticular collagen in asthma. A quantitative light and electron microscopic study.
Topics: Adult; Aerosols; Asthma; Basement Membrane; Biopsy; Bronchi; Bronchodilator Agents; Budesonide; Coll | 1992 |
Quantification of metoprolol beta 2-adrenoceptor antagonism in asthmatic patients by pharmacokinetic-pharmacodynamic modelling.
Topics: Adult; Asthma; Female; Forced Expiratory Volume; Humans; Male; Metoprolol; Middle Aged; Potassium; T | 1992 |
Measurement of bronchial responsiveness in young children: comparison of transcutaneous oxygen tension and functional residual capacity during induced bronchoconstriction and -dilatation.
Topics: Asthma; Blood Gas Monitoring, Transcutaneous; Bronchial Hyperreactivity; Bronchial Provocation Tests | 1992 |
Saliva composition in asthmatic patients after treatment with two dose levels of a beta 2-adrenoceptor agonist.
Topics: Adolescent; Adult; Albuterol; Amylases; Asthma; Buffers; Female; Hexosamines; Humans; Hydrogen-Ion C | 1990 |
Plasma terbutaline levels in nebulisation treatment of acute asthma.
Topics: Acute Disease; Adult; Aerosols; Aged; Asthma; Female; Forced Expiratory Volume; Hemodynamics; Humans | 1991 |
Saliva composition and caries development in asthmatic patients treated with beta 2-adrenoceptor agonists: a 4-year follow-up study.
Topics: Adolescent; Adult; Albuterol; Asthma; Dental Caries; DMF Index; Female; Follow-Up Studies; Humans; H | 1991 |
Hypokalaemic effect of salbutamol and terbutaline in bronchial asthma.
Topics: Adult; Aged; Albuterol; Asthma; Female; Forced Expiratory Volume; Humans; Hypokalemia; Male; Middle | 1991 |
The ventilatory and oxygen costs in the anesthetized rhesus monkey of inhaling drugs used in the therapy and diagnosis of asthma.
Topics: Administration, Inhalation; Albuterol; Anesthesia; Animals; Asthma; Cromolyn Sodium; Epinephrine; Fu | 1991 |
Pharmacologic control of plasma exudation into tracheobronchial airways.
Topics: Animals; Asthma; Bronchi; Bronchodilator Agents; Capillary Permeability; Cromolyn Sodium; Guinea Pig | 1991 |
Creatine kinase activity in patients with brittle asthma treated with long term subcutaneous terbutaline.
Topics: Adult; Aged; Asthma; Creatine Kinase; Female; Humans; Infusion Pumps; Injections, Subcutaneous; Male | 1991 |
Normal responsiveness of superficial hand veins to alpha- and beta-adrenergic stimuli in allergic asthma: effects of terbutaline and prednisolone on beta-adrenergic responsiveness.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Adult; Analysis of Variance; Asthma; Dose | 1990 |
Duration of protective effect of terbutaline sulfate and cromolyn sodium alone and in combination on exercise-induced asthma.
Topics: Adolescent; Adult; Asthma; Asthma, Exercise-Induced; Cromolyn Sodium; Drug Therapy, Combination; Exe | 1990 |
Continuous intravenous terbutaline infusions for adult patients with status asthmaticus.
Topics: Adult; Asthma; Carbon Dioxide; Heart Rate; Humans; Infusions, Intravenous; Partial Pressure; Status | 1990 |
Comment on the paper by M. Garty et al.: "Increased theophylline clearance by terbutaline in asthmatic patients" in European Journal of Clinical Pharmacology, issue 1 vol. 36, pp 25-28, 1989.
Topics: Asthma; Drug Interactions; Humans; Terbutaline; Theophylline | 1990 |
Comparison of inhaled terbutaline and inhaled terbutaline plus ipratropium bromide in acute asthmatic children.
Topics: Acute Disease; Adolescent; Asthma; Atropine Derivatives; Blood Pressure; Child; Child, Preschool; Dr | 1990 |
Safety of frequent high dose nebulized terbutaline in children with acute severe asthma.
Topics: Acute Disease; Asthma; Child; Child, Preschool; Dose-Response Relationship, Drug; Female; Humans; In | 1990 |
The bronchodilator response from increasing doses of terbutaline inhaled from a multi-dose powder inhaler (Turbuhaler).
Topics: Administration, Inhalation; Adult; Asthma; Double-Blind Method; Drug Evaluation; Forced Expiratory V | 1990 |
Management of asthma: a consensus statement.
Topics: Age Factors; Asthma; Child, Preschool; Female; Humans; Infant; Infant, Newborn; Male; Nebulizers and | 1990 |
Factors influencing the occurrence of late bronchial reactions after allergen challenge.
Topics: Adolescent; Adult; Allergens; Asthma; Bronchial Provocation Tests; Female; Humans; Hypersensitivity, | 1990 |
Histopathological support of antagonism of allergen-induced mast cell mediator release in human skin by a beta-2-agonist.
Topics: Adrenergic beta-Agonists; Adult; Allergens; Asthma; Biopsy; Female; Histamine Release; Humans; Hyper | 1986 |
[Therapeutic aspects of intractable asthma].
Topics: Adult; Aged; Asthma; Cromolyn Sodium; Female; Humans; Ketotifen; Male; Middle Aged; ortho-Aminobenzo | 1988 |
Cardiac arrhythmias during acute exacerbations of chronic airflow limitation: effect of fall in plasma potassium concentration induced by nebulised beta 2-agonist therapy.
Topics: Acute Disease; Adult; Aged; Aged, 80 and over; Albuterol; Arrhythmias, Cardiac; Asthma; Humans; Male | 1989 |
Continuous intravenous therapy with theophylline in patients with brittle bronchial asthma.
Topics: Asthma; Humans; Infusions, Intravenous; Infusions, Parenteral; Terbutaline; Theophylline | 1989 |
[Pulmonary function tests in asthmatic children in treatment with tulobuterol].
Topics: Adolescent; Asthma; Bronchodilator Agents; Child; Female; Forced Expiratory Flow Rates; Forced Expir | 1989 |
Deposition and clinical efficacy of terbutaline sulphate from Turbuhaler, a new multi-dose powder inhaler.
Topics: Adult; Aerosols; Aged; Asthma; Female; Forced Expiratory Volume; Half-Life; Humans; Lung; Male; Midd | 1989 |
The bronchodilator response from inhaled terbutaline is influenced by the mass of small particles: a study on a dry powder inhaler (Turbuhaler).
Topics: Adult; Airway Resistance; Asthma; Bronchi; Female; Forced Expiratory Volume; Humans; Male; Middle Ag | 1989 |
Comparison of inhaled terbutaline and terbutaline injection in treatment of acute asthmatic attacks in children.
Topics: Acute Disease; Adolescent; Aerosols; Asthma; Blood Pressure; Child; Child, Preschool; Female; Heart | 1989 |
Pharmacokinetics of intravenous terbutaline in asthmatic children.
Topics: Asthma; Blood Pressure; Child; Chronic Disease; Female; Heart Rate; Humans; Infusions, Intravenous; | 1989 |
Breath-actuated inhalers: comparison of terbutaline Turbohaler with salbutamol Rotahaler.
Topics: Administration, Inhalation; Adolescent; Adult; Aged; Albuterol; Asthma; Chronic Disease; Evaluation | 1989 |
Oral terbutaline alone and in combination with theophylline: dose, plasma concentration, and effect in long-term treatment of bronchial asthma.
Topics: Administration, Oral; Asthma; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Terbutal | 1989 |
Adverse effects and complications of treatment with beta-adrenergic agonist drugs. Committee on drugs, the American Academy of Allergy and Immunology.
Topics: Adolescent; Adrenergic beta-Agonists; Adult; Airway Obstruction; Asthma; Bronchodilator Agents; Card | 1985 |
Beta 2 agonists for acute asthma.
Topics: Adrenergic beta-Agonists; Albuterol; Asthma; Humans; Isoetharine; Metaproterenol; Terbutaline | 1985 |
Comparison of disodium cromoglycate, terbutaline and thiazinamium in the prevention of exercise-induced asthma and its relation to non-specific bronchial responsiveness.
Topics: Adolescent; Adult; Asthma; Asthma, Exercise-Induced; Bronchial Diseases; Cromolyn Sodium; Female; Fo | 1985 |
Response to epinephrine in children receiving oral beta-agonists.
Topics: Administration, Oral; Adolescent; Adrenergic beta-Agonists; Asthma; Child; Child, Preschool; Epineph | 1986 |
Treatment of asthma.
Topics: Acute Disease; Aerosols; Albuterol; Asthma; Humans; Terbutaline | 1986 |
Development of drug tachyphylaxis in asthmatic patients treated with beta-adrenergic drugs.
Topics: Adrenergic beta-Agonists; Adult; Aerosols; Airway Resistance; Albuterol; Asthma; Female; Forced Expi | 1987 |
Ketotifen prevents terbutaline-induced down-regulation of beta-adrenoceptors in guinea pig lung.
Topics: Adrenergic beta-Agonists; Animals; Asthma; Dose-Response Relationship, Drug; Drug Interactions; Guin | 1988 |
Dose-response relationships of intravenously administered terbutaline in children with asthma.
Topics: Adolescent; Asthma; Child; Dose-Response Relationship, Drug; Forced Expiratory Volume; Heart Rate; H | 1989 |
[Dose and time relations of the effects of various asthma sprays in diagnostic use--a contribution to practicality of the bronchospasmolysis test].
Topics: Adult; Aerosols; Aged; Asthma; Bronchitis; Bronchodilator Agents; Chronic Disease; Dose-Response Rel | 1985 |
Emergency use of nebulised bronchodilator drugs in British hospitals.
Topics: Aerosols; Albuterol; Asthma; Bronchodilator Agents; Drug Utilization; Emergencies; Hospitals, Distri | 1987 |
The beta-adrenergic receptor and bronchial hyperreactivity.
Topics: Adenylyl Cyclases; Asthma; Bronchial Diseases; Bronchial Provocation Tests; Humans; Lymphocytes; Rec | 1986 |
Pharmacodynamics (lung function tests, tremor measurements and cAMP determinations) of a single dose of 0.5 mg terbutaline subcutaneously during sustained-release theophylline medication in patients with asthmatic bronchitis.
Topics: Adult; Asthma; Bronchitis; Cyclic AMP; Delayed-Action Preparations; Drug Interactions; Female; Human | 1986 |
[Respiratory disease and clinical pharmacology--serum concentration and pharmacological effect of beta-stimulant and theophylline].
Topics: Adult; Asthma; Female; Humans; Kinetics; Male; Middle Aged; Receptors, Adrenergic, beta; Terbutaline | 1987 |
The U.S. Olympic Committee experience with exercise-induced bronchospasm, 1984.
Topics: Adult; Albuterol; Asthma; Asthma, Exercise-Induced; Cromolyn Sodium; Female; Humans; Male; Sex Facto | 1986 |
Continuous terbutaline nebulization for the treatment of severe exacerbations of asthma in children.
Topics: Administration, Inhalation; Adolescent; Asthma; Carbon Dioxide; Child; Child, Preschool; Critical Ca | 1988 |
Improvement in clinical asthma score and PaCO2 in children with severe asthma treated with continuously nebulized terbutaline.
Topics: Administration, Inhalation; Adolescent; Asthma; Carbon Dioxide; Child; Child, Preschool; Drug Admini | 1988 |
Effects of terbutaline and atenolol on large and small airways in asthmatic patients.
Topics: Administration, Inhalation; Adult; Airway Resistance; Asthma; Atenolol; Dose-Response Relationship, | 1988 |
Intravenous terbutaline and aminophylline in bronchial asthma.
Topics: Adult; Aminophylline; Asthma; Female; Humans; Injections, Intravenous; Male; Random Allocation; Terb | 1988 |
[Drug information. An agent for the optimal inhalation of asthma drugs].
Topics: Administration, Inhalation; Asthma; Drug Carriers; Humans; Terbutaline | 1988 |
Protective effect of tulobuterol on methacholine-induced bronchospasm in asthmatic children.
Topics: Adolescent; Asthma; Bronchial Spasm; Bronchodilator Agents; Child; Female; Forced Expiratory Volume; | 1988 |
[Bronchospasmolytic tests with and without a nebulizer].
Topics: Adult; Aerosols; Airway Resistance; Asthma; Female; Humans; Male; Nebulizers and Vaporizers; Terbuta | 1988 |
Turbuhaler: a new powder inhaler for administration of drugs to the airways.
Topics: Asthma; Humans; Nebulizers and Vaporizers; Particle Size; Powders; Terbutaline | 1988 |
Bambuterol, a bronchodilator prodrug with sustained action, enhances delivery of active drug to the lung.
Topics: Animals; Asthma; Bronchodilator Agents; Guinea Pigs; Humans; In Vitro Techniques; Lung; Prodrugs; Te | 1988 |
[The effect of inhalation treatment with corticosteroids and beta-sympathicomimetics on bronchial responsiveness in children].
Topics: Administration, Inhalation; Adolescent; Anti-Inflammatory Agents; Asthma; Bronchi; Budesonide; Child | 1988 |
Inhaled bronchodilator treatment via the nebuhaler in young asthmatic patients.
Topics: Aerosols; Asthma; Child; Child, Preschool; Female; Humans; Lung; Lung Volume Measurements; Male; Neb | 1988 |
Bambuterol: clinical effects of different doses of a long-acting bronchodilator prodrug.
Topics: Adult; Aged; Asthma; Bronchodilator Agents; Dose-Response Relationship, Drug; Drug Therapy; Female; | 1988 |
Cardiac arrhythmias during the combined use of intravenous aminophylline and terbutaline in status asthmaticus.
Topics: Adult; Aged; Aminophylline; Arrhythmias, Cardiac; Asthma; Drug Therapy, Combination; Electrocardiogr | 1988 |
Nebuhaler in young asthmatic children.
Topics: Asthma; Child; Child, Preschool; Humans; Nebulizers and Vaporizers; Terbutaline | 1988 |
[Asthmatic cough].
Topics: Asthma; Cough; Humans; Prognosis; Steroids; Terbutaline | 1987 |
Effect of disease severity and pharmacotherapy of asthma on oral health in asthmatic children.
Topics: Adolescent; Asthma; Bronchodilator Agents; Child; Child, Preschool; Dental Caries; Female; Gingiviti | 1987 |
Frequent parenteral terbutaline in the treatment of status asthmaticus in children.
Topics: Adolescent; Asthma; Child; Emergencies; Female; Humans; Injections, Subcutaneous; Male; Nebulizers a | 1987 |
[Terbutaline and theophyllamine infusion in acute asthma. Effect on serum potassium].
Topics: Acute Disease; Aged; Aminophylline; Asthma; Female; Humans; Infusions, Intravenous; Male; Middle Age | 1987 |
Failure of long-acting, recently introduced beta-agonist in asthma.
Topics: Albuterol; Asthma; Delayed-Action Preparations; Humans; Tablets, Enteric-Coated; Terbutaline | 1987 |
A dose-response study of inhaled terbutaline administered via Nebuhaler or nebuliser to asthmatic children.
Topics: Administration, Inhalation; Asthma; Bronchiectasis; Child; Child, Preschool; Dose-Response Relations | 1987 |
An unusual local reaction to continuous subcutaneous infused terbutaline in unstable asthmatics.
Topics: Adult; Asthma; Drug Hypersensitivity; Humans; Hypersensitivity; Infusions, Parenteral; Male; Middle | 1987 |
Post-mortem concentrations of salbutamol, terbutaline and theophylline in asthma patients.
Topics: Acute Disease; Adolescent; Adult; Aged; Aged, 80 and over; Albuterol; Animals; Asthma; Female; Human | 1987 |
[Hyperkalemia precipitated by beta 2 receptor agonists].
Topics: Aged; Albuterol; Asthma; Female; Humans; Hyperkalemia; Terbutaline | 1986 |
Effects of pulmonary inhalation of water and histamine aerosols on nasal airflow resistance in man.
Topics: Adolescent; Adult; Aerosols; Aged; Airway Resistance; Asthma; Bronchial Provocation Tests; Forced Ex | 1986 |
Effect of aerosol particle size on bronchodilatation with nebulised terbutaline in asthmatic subjects.
Topics: Adult; Aerosols; Aged; Asthma; Bronchi; Dilatation; Female; Forced Expiratory Volume; Humans; Male; | 1986 |
Pharmacokinetic-pharmacodynamic modeling of terbutaline bronchodilation in asthma.
Topics: Adolescent; Adult; Asthma; Bronchi; Humans; Injections, Subcutaneous; Kinetics; Maximal Expiratory F | 1986 |
[Fetal bigeminus following combined bronchodilator treatment of the mother].
Topics: Arrhythmias, Cardiac; Asthma; Drug Therapy, Combination; Electrocardiography; Female; Fetal Diseases | 1986 |
Failure of long acting recently introduced B-agonists in asthma.
Topics: Asthma; Delayed-Action Preparations; Humans; Kinetics; Terbutaline | 1986 |
Clinical consequences of inadequate inhalation technique in asthma therapy.
Topics: Administration, Inhalation; Adult; Aged; Asthma; Humans; Middle Aged; Respiratory Function Tests; Se | 1987 |
Effects of treatment on mortality from asthma.
Topics: Administration, Oral; Adolescent; Albuterol; Asthma; Child; Child, Preschool; Female; Humans; Inject | 1986 |
Terbutaline-induced hypotension in a pregnant asthmatic patient.
Topics: Adult; Asthma; Emergencies; Female; Humans; Hypotension; Pregnancy; Pregnancy Complications; Pregnan | 1986 |
Anti-asthma drugs and capsaicine-induced microvascular effects in lower airways.
Topics: Animals; Asthma; Bronchodilator Agents; Capillary Permeability; Capsaicin; Guinea Pigs; Lidocaine; M | 1985 |
"Noninvasive" oral treatment of asthma in the emergency room.
Topics: Acute Disease; Administration, Oral; Aerosols; Asthma; Emergency Service, Hospital; Humans; Infusion | 1985 |
Acute asthma--plasma levels and effect of terbutaline i.v. injection.
Topics: Acute Disease; Adult; Aged; Asthma; Blood Pressure; Drug Administration Schedule; Female; Heart Rate | 1985 |
Comparison of bronchodilator effect of tulobuterol and salbutamol aerosols in patients with asthma.
Topics: Adult; Albuterol; Asthma; Bronchodilator Agents; Forced Expiratory Volume; Hemodynamics; Humans; Mid | 1985 |
Terbutaline: a preliminary report of its pharmacological properties and therapeutic efficacy in asthma.
Topics: Administration, Oral; Adrenergic beta-Agonists; Aerosols; Airway Resistance; Albuterol; Asthma; Bloo | 1973 |
[Indications and effectiveness of orally administered adrenergic sympathomimetics in the prolonged treatment and in prevention of attacks of bronchial asthma].
Topics: Adrenal Cortex Hormones; Asthma; Cardiovascular System; Humans; Long-Term Care; Respiration; Respira | 1973 |
[Therapy of bronchial asthma].
Topics: Adrenal Cortex Hormones; Aminophylline; Asthma; Breathing Exercises; Bromhexine; Cromolyn Sodium; Cy | 1974 |
[Pharmacodynamic effect of terbutalin (Bricanyl) in obstructive respiratory diseases].
Topics: Adult; Asthma; Female; Humans; Male; Middle Aged; Terbutaline | 1974 |
Effect of a repeated dose of terbutaline by inhalation.
Topics: Administration, Intranasal; Adult; Aerosols; Airway Obstruction; Airway Resistance; Asthma; Blood Pr | 1974 |
Terbutaline subcutaneously injected for the treatment of bronchial asthma in children.
Topics: Acute Disease; Adolescent; Asthma; Blood Pressure; Body Weight; Bronchitis; Child; Child, Preschool; | 1974 |
A comparative trial of subcutaneous terbutaline, Th1165a and adrenaline in bronchial asthma.
Topics: Adolescent; Adult; Aged; Asthma; Bronchodilator Agents; Epinephrine; Female; Heart Rate; Humans; Inj | 1973 |
Letter: Studies of resistance to long-acting adrenergic beta-stimulators in asthmatic patients.
Topics: Asthma; Blood Pressure; Bronchi; Drug Resistance; Drug Tolerance; Heart Rate; Humans; Isoproterenol; | 1974 |
Terbutaline aerosol and blood-gas tensions.
Topics: Adult; Aerosols; Aged; Analysis of Variance; Asthma; Blood Gas Analysis; Carbon Dioxide; Female; Hum | 1974 |