Page last updated: 2024-11-04

terbutaline and Arrhythmias, Cardiac

terbutaline has been researched along with Arrhythmias, Cardiac in 31 studies

Terbutaline: A selective beta-2 adrenergic agonist used as a bronchodilator and tocolytic.
terbutaline : A member of the class of phenylethanolamines that is catechol substituted at position 5 by a 2-(tert-butylamino)-1-hydroxyethyl group.

Arrhythmias, Cardiac: Any disturbances of the normal rhythmic beating of the heart or MYOCARDIAL CONTRACTION. Cardiac arrhythmias can be classified by the abnormalities in HEART RATE, disorders of electrical impulse generation, or impulse conduction.

Research Excerpts

ExcerptRelevanceReference
"Bronchodilation and side effects of 28 days treatment with either a full therapeutic dose of theophylline slow-release preparation 500 mg twice daily (400-600 mg), a slow-release terbutaline preparation 10 mg twice daily or combinations of the 2 drugs in full or half doses were evaluated in 31 asthmatic outpatients in a double-blind, randomized crossover design."9.05Long-term oral therapy of asthma with terbutaline and theophylline, alone and combined. ( Gnosspelius, Y; Gymose, E; Laursen, LC; Taudorf, E; Weeke, B, 1985)
" Although rebound hyperkalemia after cessation of tocolytic therapy with ritodrine has been reported, there have been no reports of hyperkalemia occurring after the cessation of beta-adrenergic tocolytic therapy with terbutaline for preterm labor; we report such a case."7.72Rebound hyperkalemia after cessation of intravenous tocolytic therapy with terbutaline in the treatment of preterm labor: anesthetic implications. ( Benumof, JL; Kuczkowski, KM, 2003)
"Continuous monitoring for arrhythmias, ST-segment changes, and DBP values during variations in the dose of intravenous terbutaline, with or without epinephrine."7.70Continuous intravenous terbutaline for pediatric status asthmaticus. ( Monge, R; Peterson, BM; Schell, KH; Stephanopoulos, DE; Wyckoff, P, 1998)
"The purpose of this study was to evaluate prospectively the occurrence of cardiac arrhythmias during the combined therapy with intravenous aminophylline and terbutaline in 29 consecutive patients with status asthmaticus."7.67Cardiac arrhythmias during the combined use of intravenous aminophylline and terbutaline in status asthmaticus. ( Chauvet, JP; Iung, B; Laaban, JP; Proteau, J; Psychoyos, I; Rochemaure, J, 1988)
"After a run-in period practolol was given in the dose of 100 mg twice daily to 29 patients with chronic bronchial asthma on the indication hypertension (12) and supraventricular arrhythmia (17)."7.65Effects of practolol in combination with terbutaline in the treatment of hypertension and arrhythmias in asthmatic patients. ( Eriksson, NE; Formgren, H, 1975)
"The enhancement of arrhythmias appeared to be the result of triggering ouabain-induced delayed afterdepolarizations (DAD) into overt arrhythmia."5.28The bronchodilator terbutaline enhances digitalis-induced arrhythmia. ( Zavecz, JH, 1991)
"Bronchodilation and side effects of 28 days treatment with either a full therapeutic dose of theophylline slow-release preparation 500 mg twice daily (400-600 mg), a slow-release terbutaline preparation 10 mg twice daily or combinations of the 2 drugs in full or half doses were evaluated in 31 asthmatic outpatients in a double-blind, randomized crossover design."5.05Long-term oral therapy of asthma with terbutaline and theophylline, alone and combined. ( Gnosspelius, Y; Gymose, E; Laursen, LC; Taudorf, E; Weeke, B, 1985)
" Although rebound hyperkalemia after cessation of tocolytic therapy with ritodrine has been reported, there have been no reports of hyperkalemia occurring after the cessation of beta-adrenergic tocolytic therapy with terbutaline for preterm labor; we report such a case."3.72Rebound hyperkalemia after cessation of intravenous tocolytic therapy with terbutaline in the treatment of preterm labor: anesthetic implications. ( Benumof, JL; Kuczkowski, KM, 2003)
"Continuous monitoring for arrhythmias, ST-segment changes, and DBP values during variations in the dose of intravenous terbutaline, with or without epinephrine."3.70Continuous intravenous terbutaline for pediatric status asthmaticus. ( Monge, R; Peterson, BM; Schell, KH; Stephanopoulos, DE; Wyckoff, P, 1998)
"Arrhythmia was induced by the investigated drugs, injected intravenously: adrenaline (ADR); noradrenaline (NA); phenylephrine (PE); isoprenaline (IP); terbutaline (Tb) and salbutamol (Sb)."3.68Sympathomimetic amines and cardiac arrhythmias. ( Akavia, E; Korczyn, AD; Oppenheimer, E; Shavit, S, 1990)
"The purpose of this study was to evaluate prospectively the occurrence of cardiac arrhythmias during the combined therapy with intravenous aminophylline and terbutaline in 29 consecutive patients with status asthmaticus."3.67Cardiac arrhythmias during the combined use of intravenous aminophylline and terbutaline in status asthmaticus. ( Chauvet, JP; Iung, B; Laaban, JP; Proteau, J; Psychoyos, I; Rochemaure, J, 1988)
"Although propranolol antagonized CaCl2-induced arrhythmias in the rat due to its local anaesthetic properties, arrhythmias-protected animals died because of respiratory failure."3.66Beta-adrenoreceptor blockers and CaCl2-induced arrhythmias in the rat: discrepancies between antiarrhythmic properties and survival rate. ( Evangelista, S; Grimaldi, G; Maggi, CA; Manzini, S; Meli, A, 1983)
"After a run-in period practolol was given in the dose of 100 mg twice daily to 29 patients with chronic bronchial asthma on the indication hypertension (12) and supraventricular arrhythmia (17)."3.65Effects of practolol in combination with terbutaline in the treatment of hypertension and arrhythmias in asthmatic patients. ( Eriksson, NE; Formgren, H, 1975)
"The successful management of fetal arrhythmias is contingent on an accurate diagnosis of arrhythmia and its effects on fetal well-being."2.46Doppler echocardiography for managing fetal cardiac arrhythmia. ( Cuneo, BF; Matta, MJ, 2010)
"Treatment with terbutaline, a Na/K-ATPase-stimulating drug, resulted in attack-free periods of approximately 9 months, after which the attacks reoccurred."1.30Multiple anomalies, hypokalaemic paralysis and partial symptomatic relief by terbutaline. ( Andersen, PE; Djurhuus, MS; Jensen, BM; Klitgaard, NA; Schrøder, HD, 1998)
"The ultimate cause of death was cardiac arrhythmia, the origin of which was probably multifactorial."1.29Sudden death associated with terbutaline sulfate administration. ( Conradi, SE; Hudgens, DR, 1993)
"The enhancement of arrhythmias appeared to be the result of triggering ouabain-induced delayed afterdepolarizations (DAD) into overt arrhythmia."1.28The bronchodilator terbutaline enhances digitalis-induced arrhythmia. ( Zavecz, JH, 1991)
"The slow disappearance of the arrhythmia is a result of the prolonged half-life of theophylline in the fetus."1.27[Fetal bigeminus following combined bronchodilator treatment of the mother]. ( Neeb, U, 1986)

Research

Studies (31)

TimeframeStudies, this research(%)All Research%
pre-199016 (51.61)18.7374
1990's11 (35.48)18.2507
2000's1 (3.23)29.6817
2010's2 (6.45)24.3611
2020's1 (3.23)2.80

Authors

AuthorsStudies
Walker, AL1
Ueda, Y1
Crofton, AE1
Harris, SP1
Stern, JA1
Płusa, T1
Matta, MJ1
Cuneo, BF1
Kuczkowski, KM1
Benumof, JL1
Evangelista, S1
Grimaldi, G1
Maggi, CA1
Manzini, S1
Meli, A1
Al-Hillawi, AH1
Hayward, R1
Johnson, NM1
Harrison, P1
Roque d'Orbcastel, O1
de Fenoyl, O1
Buoncuore, A1
Laaban, JP2
Rochemaure, J2
Ravindran, R1
Viegas, OJ1
Padilla, LM1
LaBlonde, P1
Perry, KG1
Morrison, JC1
Rust, OA1
Sullivan, CA1
Martin, RW1
Naef, RW1
Tveskov, C1
Djurhuus, MS2
Klitgaard, NA2
Egstrup, K1
Hudgens, DR1
Conradi, SE1
Seider, N1
Abinader, EG1
Oliven, A1
Jensen, BM1
Andersen, PE1
Schrøder, HD1
Stephanopoulos, DE1
Monge, R1
Schell, KH1
Wyckoff, P1
Peterson, BM1
Cazzola, M1
Calderaro, F1
Califano, C1
Di Pema, F1
Vinciguerra, A1
Donner, CF1
Matera, MG1
Larsson, S1
Hirsch, SR1
Ingemarsson, I2
Formgren, H1
Eriksson, NE1
Zavecz, JH1
Oppenheimer, E1
Akavia, E1
Shavit, S1
Korczyn, AD1
Shvela, Kh1
Oltmanis, G1
Faidley, CK1
Dix, PM1
Morgan, MA1
Schechter, E1
Laursen, LC1
Taudorf, E1
Gnosspelius, Y1
Gymose, E1
Weeke, B1
Lim, R1
Walshaw, MJ1
Saltissi, S1
Hind, CR1
Laorden, ML1
Hernández, J1
Brugger, AJ1
Arulkumaran, S1
Kottegoda, SR1
Iung, B1
Chauvet, JP1
Psychoyos, I1
Proteau, J1
Neeb, U1
Thiagarajah, S1
Grynsztejn, M1
Lear, E1
Azar, I1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A 12-week, Double-blind, Multicenter, 3-crossover, Placebo Controlled and Randomized Trial to Investigate the Efficacy and Safety of 10mg and 5mg Bambuterol Tablets Once Daily in Patients With Chronic Obstructive Pulmonary Disease (COPD)[NCT01796730]Phase 460 participants (Actual)Interventional2013-02-28Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

3 reviews available for terbutaline and Arrhythmias, Cardiac

ArticleYear
Doppler echocardiography for managing fetal cardiac arrhythmia.
    Clinical obstetrics and gynecology, 2010, Volume: 53, Issue:4

    Topics: Adrenergic beta-2 Receptor Agonists; Arrhythmias, Cardiac; Dexamethasone; Echocardiography, Doppler;

2010
Long-term treatment with beta2-adrenostimulants in asthma. Side effects, selectivity, tolerance, and routes of administration.
    Acta medica Scandinavica. Supplementum, 1977, Volume: 608

    Topics: Administration, Oral; Adrenergic beta-Agonists; Aerosols; Albuterol; Arrhythmias, Cardiac; Asthma; E

1977
Complications of beta-mimetic therapy in preterm labour.
    The Australian & New Zealand journal of obstetrics & gynaecology, 1985, Volume: 25, Issue:3

    Topics: Adrenergic beta-Agonists; Adult; Arrhythmias, Cardiac; Child; Child, Preschool; Coronary Disease; Fe

1985

Trials

5 trials available for terbutaline and Arrhythmias, Cardiac

ArticleYear
Incidence of cardiac arrhythmias in patients taking slow release salbutamol and slow release terbutaline for asthma.
    British medical journal (Clinical research ed.), 1984, Feb-04, Volume: 288, Issue:6414

    Topics: Adult; Albuterol; Arrhythmias, Cardiac; Asthma; Delayed-Action Preparations; Female; Humans; Male; M

1984
Potassium and magnesium distribution, ECG changes, and ventricular ectopic beats during beta 2-adrenergic stimulation with terbutaline in healthy subjects.
    Chest, 1994, Volume: 106, Issue:6

    Topics: Adult; Arrhythmias, Cardiac; Double-Blind Method; Electrocardiography; Humans; Injections, Intraveno

1994
Cardiac arrhythmias after inhaled bronchodilators in patients with COPD and ischemic heart disease.
    Chest, 1993, Volume: 104, Issue:4

    Topics: Administration, Inhalation; Aged; Arrhythmias, Cardiac; Double-Blind Method; Electrocardiography, Am

1993
Oral bambuterol compared to inhaled salmeterol in patients with partially reversible chronic obstructive pulmonary disease.
    European journal of clinical pharmacology, 1999, Volume: 54, Issue:11

    Topics: Administration, Inhalation; Administration, Oral; Adult; Aged; Albuterol; Arrhythmias, Cardiac; Bron

1999
Long-term oral therapy of asthma with terbutaline and theophylline, alone and combined.
    European journal of respiratory diseases, 1985, Volume: 66, Issue:2

    Topics: Administration, Oral; Adolescent; Adult; Aged; Akathisia, Drug-Induced; Arrhythmias, Cardiac; Asthma

1985

Other Studies

23 other studies available for terbutaline and Arrhythmias, Cardiac

ArticleYear
Ambulatory electrocardiography, heart rate variability, and pharmacologic stress testing in cats with subclinical hypertrophic cardiomyopathy.
    Scientific reports, 2022, 02-04, Volume: 12, Issue:1

    Topics: Administration, Oral; Adrenergic beta-2 Receptor Agonists; Animals; Arrhythmias, Cardiac; Asymptomat

2022
[Agonists of beta2 adrenergic receptor in the therapy of obstructive diseases].
    Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego, 2010, Volume: 28, Issue:163

    Topics: Adrenergic beta-2 Receptor Agonists; Adrenergic beta-Agonists; Albuterol; Arrhythmias, Cardiac; Card

2010
Rebound hyperkalemia after cessation of intravenous tocolytic therapy with terbutaline in the treatment of preterm labor: anesthetic implications.
    Journal of clinical anesthesia, 2003, Volume: 15, Issue:5

    Topics: Adult; Anesthesia, Obstetrical; Arrhythmias, Cardiac; Female; Humans; Hyperkalemia; Infusions, Intra

2003
Beta-adrenoreceptor blockers and CaCl2-induced arrhythmias in the rat: discrepancies between antiarrhythmic properties and survival rate.
    Pharmacology, 1983, Volume: 27, Issue:2

    Topics: Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardi

1983
Incidence of cardiac arrhythmias in patients taking slow release salbutamol and terbutaline for asthma.
    British medical journal (Clinical research ed.), 1984, Mar-17, Volume: 288, Issue:6420

    Topics: Adult; Albuterol; Arrhythmias, Cardiac; Humans; Middle Aged; Terbutaline

1984
[Treatment of status asthmaticus. Prospective evaluation of a protocol combining aminophylline and terbutaline (44 cases)].
    Revue de pneumologie clinique, 1984, Volume: 40, Issue:5

    Topics: Adult; Aged; Aminophylline; Arrhythmias, Cardiac; Asthma; Bronchial Spasm; Carbon Dioxide; Drug Eval

1984
Anesthetic considerations in pregnant patients receiving terbutaline therapy.
    Anesthesia and analgesia, 1980, Volume: 59, Issue:5

    Topics: Adult; Anesthesia; Anesthesia, General; Anesthesia, Obstetrical; Arrhythmias, Cardiac; Cesarean Sect

1980
Incidence of adverse cardiopulmonary effects with low-dose continuous terbutaline infusion.
    American journal of obstetrics and gynecology, 1995, Volume: 173, Issue:4

    Topics: Adrenergic beta-Agonists; Angina Pectoris; Arrhythmias, Cardiac; Female; Heart Arrest; Hemodynamics;

1995
Sudden death associated with terbutaline sulfate administration.
    American journal of obstetrics and gynecology, 1993, Volume: 169, Issue:1

    Topics: Adult; Arrhythmias, Cardiac; Death, Sudden; Female; Humans; Obstetric Labor, Premature; Pregnancy; P

1993
Multiple anomalies, hypokalaemic paralysis and partial symptomatic relief by terbutaline.
    Acta paediatrica (Oslo, Norway : 1992), 1998, Volume: 87, Issue:4

    Topics: Abnormalities, Multiple; Arrhythmias, Cardiac; Child; Fatal Outcome; Humans; Hypokalemia; Male; Mand

1998
Continuous intravenous terbutaline for pediatric status asthmaticus.
    Critical care medicine, 1998, Volume: 26, Issue:10

    Topics: Adolescent; Arrhythmias, Cardiac; Blood Pressure; Bronchodilator Agents; Child; Child, Preschool; Cr

1998
Intravenous therapy with terbutaline.
    Chest, 1979, Volume: 75, Issue:5

    Topics: Adult; Arrhythmias, Cardiac; Asthma; Drug Evaluation; Female; Heart; Humans; Infusions, Parenteral;

1979
Terbutaline in obstetrics.
    Acta pharmacologica et toxicologica, 1979, Volume: 44 Suppl 2

    Topics: Arrhythmias, Cardiac; Female; Fetal Distress; Humans; Obstetric Labor Complications; Obstetric Labor

1979
Effects of practolol in combination with terbutaline in the treatment of hypertension and arrhythmias in asthmatic patients.
    Scandinavian journal of respiratory diseases, 1975, Volume: 56, Issue:4

    Topics: Adult; Aged; Arrhythmias, Cardiac; Asthma; Blood Pressure; Chronic Disease; Drug Therapy, Combinatio

1975
The bronchodilator terbutaline enhances digitalis-induced arrhythmia.
    The American journal of the medical sciences, 1991, Volume: 302, Issue:3

    Topics: Animals; Arrhythmias, Cardiac; Digitalis Glycosides; Drug Therapy, Combination; Guinea Pigs; In Vitr

1991
Sympathomimetic amines and cardiac arrhythmias.
    Cardiovascular research, 1990, Volume: 24, Issue:9

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Albuterol; Animals; Arrhythmias, Cardiac;

1990
[Comment on combined use of beta-adrenergic stimulants and beta-adrenoblockers].
    Kardiologiia, 1990, Volume: 30, Issue:9

    Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Aminophylline; Arrhythmias, Cardiac; Drug The

1990
Electrocardiographic abnormalities during ritodrine administration.
    Southern medical journal, 1990, Volume: 83, Issue:5

    Topics: Adolescent; Adult; Arrhythmias, Cardiac; Blood Glucose; Electrocardiography; Electrocardiography, Am

1990
Cardiac arrhythmias during acute exacerbations of chronic airflow limitation: effect of fall in plasma potassium concentration induced by nebulised beta 2-agonist therapy.
    Postgraduate medical journal, 1989, Volume: 65, Issue:765

    Topics: Acute Disease; Adult; Aged; Aged, 80 and over; Albuterol; Arrhythmias, Cardiac; Asthma; Humans; Male

1989
The beta-agonist drug tulobuterol decreases cardiac automaticity in the rat: comparison with isoproterenol.
    General pharmacology, 1985, Volume: 16, Issue:1

    Topics: Adrenergic beta-Agonists; Animals; Arrhythmias, Cardiac; Female; Heart; In Vitro Techniques; Isoprot

1985
Cardiac arrhythmias during the combined use of intravenous aminophylline and terbutaline in status asthmaticus.
    Chest, 1988, Volume: 94, Issue:3

    Topics: Adult; Aged; Aminophylline; Arrhythmias, Cardiac; Asthma; Drug Therapy, Combination; Electrocardiogr

1988
[Fetal bigeminus following combined bronchodilator treatment of the mother].
    Geburtshilfe und Frauenheilkunde, 1986, Volume: 46, Issue:8

    Topics: Arrhythmias, Cardiac; Asthma; Drug Therapy, Combination; Electrocardiography; Female; Fetal Diseases

1986
Ventricular arrhythmias after terbutaline administration to patients anesthetized with halothane.
    Anesthesia and analgesia, 1986, Volume: 65, Issue:4

    Topics: Aged; Anesthesia; Arrhythmias, Cardiac; Drug Interactions; Female; Halothane; Humans; Male; Middle A

1986