terbutaline has been researched along with Amyotrophic Lateral Sclerosis in 1 studies
Terbutaline: A selective beta-2 adrenergic agonist used as a bronchodilator and tocolytic.
terbutaline : A member of the class of phenylethanolamines that is catechol substituted at position 5 by a 2-(tert-butylamino)-1-hydroxyethyl group.
Amyotrophic Lateral Sclerosis: A degenerative disorder affecting upper MOTOR NEURONS in the brain and lower motor neurons in the brain stem and SPINAL CORD. Disease onset is usually after the age of 50 and the process is usually fatal within 3 to 6 years. Clinical manifestations include progressive weakness, atrophy, FASCICULATION, hyperreflexia, DYSARTHRIA, dysphagia, and eventual paralysis of respiratory function. Pathologic features include the replacement of motor neurons with fibrous ASTROCYTES and atrophy of anterior SPINAL NERVE ROOTS and corticospinal tracts. (From Adams et al., Principles of Neurology, 6th ed, pp1089-94)
| Excerpt | Relevance | Reference |
|---|---|---|
| " Interestingly, the prediction suggests that terbutaline sulfate, which is widely used for asthma, is a promising candidate for amyotrophic lateral sclerosis for which there are few therapeutic options." | 7.81 | Repurpose terbutaline sulfate for amyotrophic lateral sclerosis using electronic medical records. ( Butte, AJ; Chung, AY; Kim, H; Kim, J; Lee, K; Paik, H; Park, HC; Park, RW; Suk, K, 2015) |
| " Interestingly, the prediction suggests that terbutaline sulfate, which is widely used for asthma, is a promising candidate for amyotrophic lateral sclerosis for which there are few therapeutic options." | 3.81 | Repurpose terbutaline sulfate for amyotrophic lateral sclerosis using electronic medical records. ( Butte, AJ; Chung, AY; Kim, H; Kim, J; Lee, K; Paik, H; Park, HC; Park, RW; Suk, K, 2015) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Paik, H | 1 |
| Chung, AY | 1 |
| Park, HC | 1 |
| Park, RW | 1 |
| Suk, K | 1 |
| Kim, J | 1 |
| Kim, H | 1 |
| Lee, K | 1 |
| Butte, AJ | 1 |
1 other study available for terbutaline and Amyotrophic Lateral Sclerosis
| Article | Year |
|---|---|
Repurpose terbutaline sulfate for amyotrophic lateral sclerosis using electronic medical records.
Topics: Amyotrophic Lateral Sclerosis; Data Mining; Databases, Factual; Datasets as Topic; Drug Repositionin | 2015 |