Page last updated: 2024-11-04

terazosin and Acute Liver Injury, Drug-Induced

terazosin has been researched along with Acute Liver Injury, Drug-Induced in 6 studies

Terazosin: induces decreased blood pressure; used in the treatment of benign prostatic hyperplasia

Research Excerpts

ExcerptRelevanceReference
" Prazosin prevented hepatotoxicity when administered 1 h before a toxic paracetamol insult and importantly, when administered up to 1 h post paracetamol injection."1.35alpha(1)-Adrenoceptor antagonists prevent paracetamol-induced hepatotoxicity in mice. ( Kitteringham, NR; Macdonald, I; Park, BK; Randle, LE; Sathish, JG; Williams, DP, 2008)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (33.33)29.6817
2010's4 (66.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Liu, Z1
Shi, Q1
Ding, D1
Kelly, R1
Fang, H1
Tong, W2
Sakatis, MZ1
Reese, MJ1
Harrell, AW1
Taylor, MA1
Baines, IA1
Chen, L1
Bloomer, JC1
Yang, EY1
Ellens, HM1
Ambroso, JL1
Lovatt, CA1
Ayrton, AD1
Clarke, SE1
Morgan, RE1
van Staden, CJ1
Chen, Y1
Kalyanaraman, N1
Kalanzi, J1
Dunn, RT1
Afshari, CA1
Hamadeh, HK1
Chen, M1
Suzuki, A1
Thakkar, S1
Yu, K1
Hu, C1
Fernández Salazar, L1
Palencia García, A1
Randle, LE1
Sathish, JG1
Kitteringham, NR1
Macdonald, I1
Williams, DP1
Park, BK1

Reviews

1 review available for terazosin and Acute Liver Injury, Drug-Induced

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Pr

2016

Other Studies

5 other studies available for terazosin and Acute Liver Injury, Drug-Induced

ArticleYear
Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).
    PLoS computational biology, 2011, Volume: 7, Issue:12

    Topics: Animals; Anti-Infective Agents; Anti-Inflammatory Agents; Chemical and Drug Induced Liver Injury; Da

2011
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
    Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10

    Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme

2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily

2013
[Hepatotoxicity induced by terazosin].
    Medicina clinica, 2003, Feb-01, Volume: 120, Issue:3

    Topics: Adrenergic alpha-Antagonists; Chemical and Drug Induced Liver Injury; Humans; Hypertension; Liver; L

2003
alpha(1)-Adrenoceptor antagonists prevent paracetamol-induced hepatotoxicity in mice.
    British journal of pharmacology, 2008, Volume: 153, Issue:4

    Topics: Acetaminophen; Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Antagonists; Animals; Catec

2008