Page last updated: 2024-08-24

tenofovir and Herpes Genitalis

tenofovir has been researched along with Herpes Genitalis in 23 studies

Research

Studies (23)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (8.70)29.6817
2010's21 (91.30)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Abbai, NS; Naidoo, S; Nyirenda, M; Ramjee, G1
Andrei, G; Gillemot, S; Snoeck, R; Topalis, D1
Chirenje, ZM; Deal, C; Hendrix, CW; Hillier, SL; Kelly, C; Marrazzo, JM; Marzinke, MA; Morrow, RA; Piper, J; Rabe, L; Richardson, B; Schwartz, JL1
Anderson, SM; Doncel, GF; Gajer, P; Marzinke, MA; Ravel, J; Schwartz, JL; Thurman, AR; Yousefieh, N1
Baeten, JM; Celum, C; Irungu, E; Katabira, E; Lingappa, JR; Lund, JM; Meyers, AFA; Mugo, N; Muwonge, TR; Pattacini, L; Plews, M; Richert-Spuhler, LE1
Herold, BC; Jandl, T; Kiser, PF; Nagaraja, U; Nixon, B; Taneva, E; Teller, RS; Wang, Y1
Cox, AP; Delany-Moretlwe, S; Foss, AM; Heise, L; Mertenskoetter, T; Meyer-Rath, G; Rees, H; Terris-Prestholt, F; Vickerman, P; Watts, CH1
Baeten, JM; Celum, C; Donnell, D; Fife, KH; Hendrix, CW; Hong, T; Morrow, RA; Mujugira, A; Nakku-Joloba, E; Thomas, KK1
Alt, C; Shankar, GN1
Bender Ignacio, RA; Huang, ML; Johnston, C; Magaret, AS; Marrazzo, J; Perti, T; Rajagopal, S; Selke, S; Stevens, CE; Wald, A1
Abdool Karim, Q; Abdool Karim, SS; Baxter, C; Gengiah, TN; Grobler, AC; Kashuba, A; Kharsany, AB; Mansoor, LE; Mindel, A; Samsunder, N; Werner, L1
Cheshenko, N; Crooker, K; Frank, B; Herold, BC; Kiser, PF; Mesquita, PM; Ott, A; Park, SH; Su, JT; Szleifer, I; Taneva, E1
Brand, RM; Carballo-Diéguez, A; Cranston, RD; Dolezal, C; Duffill, K; Engstrom, JC; Febo, I; Frasca, T; Giguere, R; Jacobson, C; Leu, CS; Mayer, KH; McGowan, I; Nikiforov, A; Park, SY; Schwartz, JL; Siegel, A1
Cheshenko, N; Fakioglu, E; Herold, BC; Keller, MJ; Mesquita, PM; Wilson, SS1
Andrei, G; Balestra, E; Balzarini, J; Cihlar, T; Introini, A; Lisco, A; Margolis, L; Perno, CF; Snoeck, R; van den Oord, J; Vanpouille, C1
Baum, MM; Butkyavichene, I; Clark, MR; Friend, DR; Gilman, J; Kennedy, S; Kopin, E; Malone, AM; Moss, JA; Motamedi, M; Nguyen, C; Smith, TJ; Vincent, KL1
Friend, DR1
Herold, BC; Huber, AM; Kiser, PF; Mesquita, PM; Rastogi, R; Segarra, TJ; Teller, RS; Torres, NM1
Abdool Karim, Q; Abdool Karim, SS; Altfeld, M; Carr, WH; Naranbhai, V; Ndung'u, T1
Abdool Karim, Q; Abdool Karim, SS; Altfeld, M; Carr, WH; Durgiah, R; Naranbhai, V; Samsunder, N; Sibeko, S1
Melchjorsen, J; Paludan, SR; Reinert, LS; Søgaard, OS; Tolstrup, M; Vibholm, L; Østergaard, L1
Cohen, J1

Reviews

1 review(s) available for tenofovir and Herpes Genitalis

ArticleYear
Drug delivery in multiple indication (multipurpose) prevention technologies: systems to prevent HIV-1 transmission and unintended pregnancies or HSV-2 transmission.
    Expert opinion on drug delivery, 2012, Volume: 9, Issue:4

    Topics: Adenine; Administration, Intravaginal; Anti-Infective Agents; Antiviral Agents; Biopharmaceutics; Contraception; Disease Transmission, Infectious; Drug Delivery Systems; Female; Herpes Genitalis; Herpesvirus 2, Human; HIV Infections; HIV-1; Humans; Organophosphonates; Pregnancy; Pregnancy Complications, Infectious; Pregnancy, Unplanned; Tenofovir

2012

Trials

8 trial(s) available for tenofovir and Herpes Genitalis

ArticleYear
Prevalent Herpes Simplex Virus-2 Increases the Risk of Incident Bacterial Vaginosis in Women from South Africa.
    AIDS and behavior, 2018, Volume: 22, Issue:7

    Topics: Administration, Intravaginal; Administration, Oral; Adult; Cross-Sectional Studies; Developing Countries; Double-Blind Method; Emtricitabine, Tenofovir Disoproxil Fumarate Drug Combination; Female; Gels; Herpes Genitalis; Herpesvirus 2, Human; HIV Infections; HIV Seronegativity; Humans; Incidence; Risk Factors; South Africa; Tenofovir; Unsafe Sex; Vaginosis, Bacterial; Young Adult

2018
Tenofovir Gel for Prevention of Herpes Simplex Virus Type 2 Acquisition: Findings From the VOICE Trial.
    The Journal of infectious diseases, 2019, 05-24, Volume: 219, Issue:12

    Topics: Adolescent; Adult; Antiviral Agents; Double-Blind Method; Female; Herpes Genitalis; Herpesvirus 2, Human; HIV Infections; HIV-1; Humans; Incidence; Pre-Exposure Prophylaxis; Sexual Behavior; Tenofovir; Vaginal Creams, Foams, and Jellies; Young Adult

2019
Vaginal microbiota and mucosal pharmacokinetics of tenofovir in healthy women using tenofovir and tenofovir/levonorgestrel vaginal rings.
    PloS one, 2019, Volume: 14, Issue:5

    Topics: Adenine; Adult; Anti-HIV Agents; Antiviral Agents; Contraceptive Agents, Hormonal; Contraceptive Devices, Female; Device Removal; Female; Herpes Genitalis; HIV Infections; Humans; Levonorgestrel; Microbiota; Middle Aged; Mucous Membrane; Organophosphates; Tenofovir; Vagina; Young Adult

2019
Pre-exposure prophylaxis differentially alters circulating and mucosal immune cell activation in herpes simplex virus type 2 seropositive women.
    AIDS (London, England), 2019, 11-15, Volume: 33, Issue:14

    Topics: Adult; Female; Genitalia, Female; Herpes Genitalis; Herpesvirus 2, Human; HIV Infections; Humans; Immunity, Mucosal; Mucous Membrane; Pre-Exposure Prophylaxis; T-Lymphocytes; Tenofovir; Virus Shedding

2019
Daily oral tenofovir and emtricitabine-tenofovir preexposure prophylaxis reduces herpes simplex virus type 2 acquisition among heterosexual HIV-1-uninfected men and women: a subgroup analysis of a randomized trial.
    Annals of internal medicine, 2014, 07-01, Volume: 161, Issue:1

    Topics: Adenine; Administration, Oral; Adult; Anti-Retroviral Agents; Antiviral Agents; Deoxycytidine; Drug Therapy, Combination; Emtricitabine; Female; Herpes Genitalis; Herpesvirus 2, Human; Heterosexuality; HIV Infections; HIV Seronegativity; HIV-1; Humans; Incidence; Male; Medication Adherence; Organophosphonates; RNA, Viral; Tenofovir

2014
Oral and Vaginal Tenofovir for Genital Herpes Simplex Virus Type 2 Shedding in Immunocompetent Women: A Double-Blind, Randomized, Cross-over Trial.
    The Journal of infectious diseases, 2015, Dec-15, Volume: 212, Issue:12

    Topics: Administration, Intravaginal; Administration, Oral; Adult; Antiviral Agents; Cross-Over Studies; Double-Blind Method; Female; Herpes Genitalis; Herpesvirus 2, Human; Humans; Middle Aged; Placebos; Tenofovir; Treatment Outcome; Virus Shedding

2015
Tenofovir Gel for the Prevention of Herpes Simplex Virus Type 2 Infection.
    The New England journal of medicine, 2015, Aug-06, Volume: 373, Issue:6

    Topics: Adenine; Administration, Intravaginal; Adult; Double-Blind Method; Female; Follow-Up Studies; Gels; Herpes Genitalis; Herpesvirus 2, Human; HIV Infections; HIV Seronegativity; Humans; Incidence; Kaplan-Meier Estimate; Organophosphonates; Reverse Transcriptase Inhibitors; Tenofovir; Young Adult

2015
Project Gel a Randomized Rectal Microbicide Safety and Acceptability Study in Young Men and Transgender Women.
    PloS one, 2016, Volume: 11, Issue:6

    Topics: Administration, Rectal; Adolescent; Adult; Anti-HIV Agents; Chlamydia Infections; Cross-Sectional Studies; Female; Gels; Herpes Genitalis; HIV Infections; Homosexuality, Male; Humans; Male; Sexually Transmitted Diseases; Tenofovir; Transgender Persons; Young Adult

2016

Other Studies

14 other study(ies) available for tenofovir and Herpes Genitalis

ArticleYear
The Anti-Human Immunodeficiency Virus Drug Tenofovir, a Reverse Transcriptase Inhibitor, Also Targets the Herpes Simplex Virus DNA Polymerase.
    The Journal of infectious diseases, 2018, 02-14, Volume: 217, Issue:5

    Topics: Acyclovir; Amino Acid Substitution; Antiviral Agents; Cells, Cultured; DNA Mutational Analysis; DNA-Directed DNA Polymerase; Drug Resistance, Viral; Exodeoxyribonucleases; Foscarnet; Herpes Genitalis; Herpes Simplex; Herpesvirus 1, Human; Herpesvirus 2, Human; Humans; Mutation, Missense; Organophosphonates; Pyrimidines; Reverse Transcriptase Inhibitors; Selection, Genetic; Sequence Analysis, DNA; Tenofovir; Viral Proteins

2018
Vaginally delivered tenofovir disoproxil fumarate provides greater protection than tenofovir against genital herpes in a murine model of efficacy and safety.
    Antimicrobial agents and chemotherapy, 2014, Volume: 58, Issue:2

    Topics: Adenine; Administration, Intravaginal; Animals; Antiviral Agents; Contraceptive Devices, Female; Disease Models, Animal; Drug Administration Schedule; Female; Herpes Genitalis; Herpesvirus 2, Human; Humans; Mice; Mice, Inbred BALB C; Organophosphonates; Survival Analysis; Tenofovir; Vagina; Vaginal Creams, Foams, and Jellies

2014
Cost-effectiveness of tenofovir gel in urban South Africa: model projections of HIV impact and threshold product prices.
    BMC infectious diseases, 2014, Jan-09, Volume: 14

    Topics: Adenine; Anti-HIV Agents; Circumcision, Male; Cost-Benefit Analysis; Female; Forecasting; Herpes Genitalis; Herpesvirus 2, Human; HIV Infections; HIV Seropositivity; Humans; Incidence; Male; Models, Economic; Organophosphonates; Prevalence; South Africa; Tenofovir

2014
Prophylactic treatment with a novel bioadhesive gel formulation containing aciclovir and tenofovir protects from HSV-2 infection.
    The Journal of antimicrobial chemotherapy, 2014, Volume: 69, Issue:12

    Topics: Acrylic Resins; Acyclovir; Adenine; Animals; Anti-Infective Agents; Chlorocebus aethiops; Disease Models, Animal; Drug-Related Side Effects and Adverse Reactions; Female; Herpes Genitalis; Herpesvirus 2, Human; Mice, Inbred BALB C; Organophosphonates; Poloxamer; Rabbits; Rats, Sprague-Dawley; Tenofovir; Treatment Outcome; Vaginal Creams, Foams, and Jellies; Vero Cells

2014
Differential Mechanisms of Tenofovir and Tenofovir Disoproxil Fumarate Cellular Transport and Implications for Topical Preexposure Prophylaxis.
    Antimicrobial agents and chemotherapy, 2015, Dec-28, Volume: 60, Issue:3

    Topics: Administration, Intravaginal; Anti-HIV Agents; Biological Transport; Carboxylic Ester Hydrolases; Cell Line; Chromatography, High Pressure Liquid; Endocytosis; Epithelial Cells; Female; Herpes Genitalis; Herpesvirus 2, Human; HIV Infections; HIV-1; Humans; Nitrophenols; Organophosphorus Compounds; T-Lymphocytes; Tandem Mass Spectrometry; Tenofovir

2015
Susceptibility to genital herpes as a biomarker predictive of increased HIV risk: expansion of a murine model of microbicide safety.
    Antiviral therapy, 2009, Volume: 14, Issue:8

    Topics: Adenine; Administration, Intravaginal; Animals; Anti-Infective Agents; Antiviral Agents; Biomarkers; Disease Models, Animal; Disease Susceptibility; Female; Herpes Genitalis; Herpesvirus 2, Human; HIV Infections; Mice; Mice, Inbred BALB C; Naphthalenesulfonates; Nonoxynol; Organophosphonates; Polymers; Predictive Value of Tests; Risk Assessment; Tenofovir

2009
Prevention. Study reveals that vaginal gel reduces HIV, herpes.
    AIDS policy & law, 2010, Volume: 25, Issue:10

    Topics: Adenine; Female; Gels; Herpes Genitalis; HIV Infections; Humans; Organophosphonates; Reverse Transcriptase Inhibitors; Tenofovir; Vagina

2010
Topical tenofovir, a microbicide effective against HIV, inhibits herpes simplex virus-2 replication.
    Cell host & microbe, 2011, Oct-20, Volume: 10, Issue:4

    Topics: Adenine; Administration, Topical; Animals; Anti-Infective Agents; Cells, Cultured; DNA-Directed DNA Polymerase; DNA, Viral; Exodeoxyribonucleases; Herpes Genitalis; Herpesvirus 2, Human; HIV Reverse Transcriptase; Humans; Mice; Molecular Sequence Data; Nucleic Acid Synthesis Inhibitors; Organophosphonates; Sequence Analysis, DNA; Tenofovir; Thymidine Kinase; Viral Proteins

2011
Simultaneous delivery of tenofovir and acyclovir via an intravaginal ring.
    Antimicrobial agents and chemotherapy, 2012, Volume: 56, Issue:2

    Topics: Acyclovir; Adenine; Administration, Intravaginal; Animals; Anti-HIV Agents; Antiviral Agents; Delayed-Action Preparations; Disease Models, Animal; Drug Combinations; Drug Delivery Systems; Equipment Design; Female; Herpes Genitalis; Herpesvirus 2, Human; HIV Infections; HIV-1; Humans; Organophosphonates; Rabbits; Sexually Transmitted Diseases, Viral; Tenofovir; Treatment Outcome

2012
Intravaginal ring delivery of tenofovir disoproxil fumarate for prevention of HIV and herpes simplex virus infection.
    The Journal of antimicrobial chemotherapy, 2012, Volume: 67, Issue:7

    Topics: Adenine; Antiviral Agents; Cell Culture Techniques; Chemoprevention; Contraceptive Devices, Female; Female; Herpes Genitalis; HIV; HIV Infections; Humans; Organ Culture Techniques; Organophosphonates; Simplexvirus; Tenofovir

2012
Natural killer cell function in women at high risk for HIV acquisition: insights from a microbicide trial.
    AIDS (London, England), 2012, Sep-10, Volume: 26, Issue:14

    Topics: Adenine; Administration, Topical; Adult; Anti-HIV Agents; Case-Control Studies; CD4-Positive T-Lymphocytes; Cell Proliferation; Clinical Trials as Topic; Disease Susceptibility; Female; Flow Cytometry; Herpes Genitalis; HIV Seropositivity; HIV-1; Humans; Interferon-gamma; Interleukin-2; Killer Cells, Natural; Lymphocyte Activation; Middle Aged; Organophosphonates; Risk Assessment; Sexual Behavior; South Africa; Tenofovir; Vaginal Creams, Foams, and Jellies

2012
Innate immune activation enhances hiv acquisition in women, diminishing the effectiveness of tenofovir microbicide gel.
    The Journal of infectious diseases, 2012, Oct-01, Volume: 206, Issue:7

    Topics: Adenine; Adult; Anti-HIV Agents; Avian Proteins; Case-Control Studies; Coinfection; Cytokines; Disease Susceptibility; Female; Herpes Genitalis; Herpesvirus 2, Human; HIV Infections; Humans; Immunity, Innate; Logistic Models; Lymphocyte Activation; Organophosphonates; Platelet Count; Principal Component Analysis; Randomized Controlled Trials as Topic; Risk Factors; Tenofovir; Vaginal Creams, Foams, and Jellies; Young Adult

2012
Antiviral and immunological effects of tenofovir microbicide in vaginal herpes simplex virus 2 infection.
    AIDS research and human retroviruses, 2012, Volume: 28, Issue:11

    Topics: Adenine; Administration, Topical; Animals; Anti-Infective Agents; Antiviral Agents; Cells, Cultured; Disease Models, Animal; Female; Herpes Genitalis; Interferon-gamma; Interleukin-2; Mice; Mice, Inbred C57BL; Organophosphonates; Tenofovir; Tumor Necrosis Factor-alpha; Vagina; Vaginal Creams, Foams, and Jellies; Virus Shedding

2012
HIV/AIDS. Prevention cocktails: combining tools to Stop HIV's spread.
    Science (New York, N.Y.), 2005, Aug-12, Volume: 309, Issue:5737

    Topics: Acyclovir; Adenine; Anti-HIV Agents; Antidepressive Agents, Second-Generation; Antiviral Agents; Bupropion; Circumcision, Male; Clinical Trials as Topic; Contraceptive Devices, Female; Female; Herpes Genitalis; Herpesvirus 2, Human; HIV; HIV Infections; Humans; Hygiene; Male; Organophosphonates; Sexual Behavior; Tenofovir; Viral Load

2005