tenatoprazole and Arthritis--Rheumatoid

tenatoprazole has been researched along with Arthritis--Rheumatoid* in 1 studies

Other Studies

1 other study(ies) available for tenatoprazole and Arthritis--Rheumatoid

Article	Year
Discovery of the First Selective IDO2 Inhibitor As Novel Immunotherapeutic Avenues for Rheumatoid Arthritis. Journal of medicinal chemistry, 2022, 11-10, Volume: 65, Issue:21 Indoleamine 2,3-dioxygenase 2 (IDO2), a closely related homologue of well-studied immunomodulatory enzyme IDO1, has been identified as a pathogenic mediator of inflammatory autoimmunity in preclinical models. Therapeutic targeting IDO2 in autoimmune diseases has been challenging due to the lack of small-molecule IDO2 inhibitors. Here, based on our previously developed IDO1/IDO2 dual inhibitor, guided by the homology model of the IDO2 structure, we discovered compound Topics: Animals; Arthritis, Experimental; Arthritis, Rheumatoid; Immunotherapy; Indoleamine-Pyrrole 2,3,-Dioxygenase; Mice; Rats	2022

Article

Year

Discovery of the First Selective IDO2 Inhibitor As Novel Immunotherapeutic Avenues for Rheumatoid Arthritis.

Journal of medicinal chemistry, 2022, 11-10, Volume: 65, Issue:21

Indoleamine 2,3-dioxygenase 2 (IDO2), a closely related homologue of well-studied immunomodulatory enzyme IDO1, has been identified as a pathogenic mediator of inflammatory autoimmunity in preclinical models. Therapeutic targeting IDO2 in autoimmune diseases has been challenging due to the lack of small-molecule IDO2 inhibitors. Here, based on our previously developed IDO1/IDO2 dual inhibitor, guided by the homology model of the IDO2 structure, we discovered compound

Topics: Animals; Arthritis, Experimental; Arthritis, Rheumatoid; Immunotherapy; Indoleamine-Pyrrole 2,3,-Dioxygenase; Mice; Rats

2022