Page last updated: 2024-11-04

tempol-h and Huntington Disease

tempol-h has been researched along with Huntington Disease in 1 studies

TEMPOL-H: hydroxylamine (protonated, reduced) form of TEMPOL; a N-hydroxyl form of LASTAR A; TEMPOL is paramagnetic radical used in NMR as SPIN LABELS whereas TEMPOL-H is not
4-hydroxy-TEMPO : A member of the class of aminoxyls that is TEMPO carrying a hydroxy substituent at position 4. It is a radical scavenger which exhibits anti-inflammatory and analgesic properties.

Huntington Disease: A familial disorder inherited as an autosomal dominant trait and characterized by the onset of progressive CHOREA and DEMENTIA in the fourth or fifth decade of life. Common initial manifestations include paranoia; poor impulse control; DEPRESSION; HALLUCINATIONS; and DELUSIONS. Eventually intellectual impairment; loss of fine motor control; ATHETOSIS; and diffuse chorea involving axial and limb musculature develops, leading to a vegetative state within 10-15 years of disease onset. The juvenile variant has a more fulminant course including SEIZURES; ATAXIA; dementia; and chorea. (From Adams et al., Principles of Neurology, 6th ed, pp1060-4)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Sandhir, R1
Mahajan, N1
Mehrotra, A1
Aggarwal, A1
Sunkaria, A1

Other Studies

1 other study available for tempol-h and Huntington Disease

ArticleYear
4-hydroxy tempo improves mitochondrial and neurobehavioral deficits in experimental model of Huntington's disease.
    Synapse (New York, N.Y.), 2015, Volume: 69, Issue:3

    Topics: Animals; Catalase; Cognition; Cyclic N-Oxides; Female; Free Radical Scavengers; Huntington Disease;

2015