tempo-carboxylic-acid and Ataxia-Telangiectasia

tempo-carboxylic-acid has been researched along with Ataxia-Telangiectasia* in 1 studies

Other Studies

1 other study(ies) available for tempo-carboxylic-acid and Ataxia-Telangiectasia

ArticleYear
The impact of carboxy nitroxide antioxidants on irradiated ataxia telangiectasia cells.
    Free radical biology & medicine, 2004, Oct-01, Volume: 37, Issue:7

    Three water-soluble carboxy nitroxide antioxidants, 5-carboxy-1,1,3,3-tetramethylisoindolin-2-yloxyl, 4-carboxy-2,2,6,6-tetramethylpiperidin-1-yloxyl, and 3-carboxy-2,2,5,5-tetramethylpyrrolidin-1-yloxyl, show significant impact on the postirradiation survival rates of ataxia telangiectasia (A-T) cells compared to normal cells, an assay which represents a model for understanding the impact of ROS damage on the A-T phenotype. The effects of these antioxidants are much more significant than those of vitamin E or Trolox (a water-soluble vitamin E analog), studied using the same cell survival model.

    Topics: Antioxidants; Ataxia Telangiectasia; Cell Proliferation; Cell Survival; Cells, Cultured; Chromosome Aberrations; Cyclic N-Oxides; Humans; Indoles; Molecular Structure; Pyrrolidines

2004