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temozolomide and Triple Negative Breast Neoplasms

temozolomide has been researched along with Triple Negative Breast Neoplasms in 6 studies

Triple Negative Breast Neoplasms: Breast neoplasms that do not express ESTROGEN RECEPTORS; PROGESTERONE RECEPTORS; and do not overexpress the NEU RECEPTOR/HER-2 PROTO-ONCOGENE PROTEIN.

Research Excerpts

ExcerptRelevanceReference
"Temozolomide profoundly prevented the outgrowth of experimental brain metastases of breast cancer in an MGMT-dependent manner."7.80Profound prevention of experimental brain metastases of breast cancer by temozolomide in an MGMT-dependent manner. ( Biernat, W; Duchnowska, R; Gril, B; Hewitt, SM; Hua, E; Jassem, J; Liewehr, DJ; Palmieri, D; Qian, Y; Sosińska-Mielcarek, K; Stark, AM; Steeg, PS; Steinberg, SM; Woditschka, S, 2014)
"Temozolomide profoundly prevented the outgrowth of experimental brain metastases of breast cancer in an MGMT-dependent manner."3.80Profound prevention of experimental brain metastases of breast cancer by temozolomide in an MGMT-dependent manner. ( Biernat, W; Duchnowska, R; Gril, B; Hewitt, SM; Hua, E; Jassem, J; Liewehr, DJ; Palmieri, D; Qian, Y; Sosińska-Mielcarek, K; Stark, AM; Steeg, PS; Steinberg, SM; Woditschka, S, 2014)
"Zj6413 treated breast cancers (BCs) showed an elevated level of DNA damage evidenced by the accumulation of γ-H2AX foci and DNA damaged related proteins."1.43Poly (ADP-ribose) polymerases inhibitor, Zj6413, as a potential therapeutic agent against breast cancer. ( Chen, J; Chen, X; Ji, M; Jin, J; Xu, B; Xue, N; Zhou, J; Zhou, Q, 2016)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's5 (83.33)24.3611
2020's1 (16.67)2.80

Authors

AuthorsStudies
Papeo, G1
Posteri, H1
Borghi, D1
Busel, AA1
Caprera, F1
Casale, E1
Ciomei, M1
Cirla, A1
Corti, E1
D'Anello, M1
Fasolini, M1
Forte, B1
Galvani, A1
Isacchi, A1
Khvat, A1
Krasavin, MY1
Lupi, R1
Orsini, P1
Perego, R1
Pesenti, E1
Pezzetta, D1
Rainoldi, S1
Riccardi-Sirtori, F1
Scolaro, A1
Sola, F1
Zuccotto, F1
Felder, ER1
Donati, D1
Montagnoli, A1
Xiao, G1
Lundine, D1
Annor, GK1
Canar, J1
Ellison, V1
Polotskaia, A1
Donabedian, PL1
Reiner, T1
Khramtsova, GF1
Olopade, OI1
Mazo, A1
Bargonetti, J1
Martínez-Aranda, A1
Hernández, V1
Picón, C1
Modolell, I1
Sierra, A1
Chen, TC1
Cho, HY1
Wang, W1
Barath, M1
Sharma, N1
Hofman, FM1
Schönthal, AH1
Palmieri, D1
Duchnowska, R1
Woditschka, S1
Hua, E1
Qian, Y1
Biernat, W1
Sosińska-Mielcarek, K1
Gril, B1
Stark, AM1
Hewitt, SM1
Liewehr, DJ1
Steinberg, SM1
Jassem, J1
Steeg, PS1
Zhou, Q1
Ji, M1
Zhou, J1
Jin, J1
Xue, N1
Chen, J1
Xu, B1
Chen, X1

Other Studies

6 other studies available for temozolomide and Triple Negative Breast Neoplasms

ArticleYear
Discovery of 2-[1-(4,4-Difluorocyclohexyl)piperidin-4-yl]-6-fluoro-3-oxo-2,3-dihydro-1H-isoindole-4-carboxamide (NMS-P118): A Potent, Orally Available, and Highly Selective PARP-1 Inhibitor for Cancer Therapy.
    Journal of medicinal chemistry, 2015, Sep-10, Volume: 58, Issue:17

    Topics: Administration, Oral; Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols

2015
Gain-of-Function Mutant p53 R273H Interacts with Replicating DNA and PARP1 in Breast Cancer.
    Cancer research, 2020, 02-01, Volume: 80, Issue:3

    Topics: Antineoplastic Agents, Alkylating; Cell Proliferation; DNA Replication; DNA, Neoplasm; Female; Gain

2020
Development of a preclinical therapeutic model of human brain metastasis with chemoradiotherapy.
    International journal of molecular sciences, 2013, Apr-16, Volume: 14, Issue:4

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Chemoradiotherapy; Da

2013
A novel temozolomide-perillyl alcohol conjugate exhibits superior activity against breast cancer cells in vitro and intracranial triple-negative tumor growth in vivo.
    Molecular cancer therapeutics, 2014, Volume: 13, Issue:5

    Topics: Animals; Brain Neoplasms; Cell Line, Tumor; Cell Survival; Dacarbazine; Disease Models, Animal; DNA

2014
Profound prevention of experimental brain metastases of breast cancer by temozolomide in an MGMT-dependent manner.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2014, May-15, Volume: 20, Issue:10

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Breast Neoplasms; Cell Line, Tumor; Dac

2014
Poly (ADP-ribose) polymerases inhibitor, Zj6413, as a potential therapeutic agent against breast cancer.
    Biochemical pharmacology, 2016, May-01, Volume: 107

    Topics: Animals; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Apoptosi

2016