Page last updated: 2024-11-04

temozolomide and Thymus Neoplasms

temozolomide has been researched along with Thymus Neoplasms in 3 studies

Thymus Neoplasms: Tumors or cancer of the THYMUS GLAND.

Research Excerpts

ExcerptRelevanceReference
"The authors retrospectively evaluated 3 patients with progressive, metastatic neuroendocrine tumors of the thymus who were treated with a combination of capecitabine and temozolomide."7.79Treatment of metastatic neuroendocrine tumors of the thymus with capecitabine and temozolomide: a case series. ( Centeno, B; Kvols, L; Morse, B; Saranga-Perry, V; Strosberg, J, 2013)
"The authors retrospectively evaluated 3 patients with progressive, metastatic neuroendocrine tumors of the thymus who were treated with a combination of capecitabine and temozolomide."3.79Treatment of metastatic neuroendocrine tumors of the thymus with capecitabine and temozolomide: a case series. ( Centeno, B; Kvols, L; Morse, B; Saranga-Perry, V; Strosberg, J, 2013)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (33.33)18.2507
2000's0 (0.00)29.6817
2010's2 (66.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Crona, J1
Björklund, P1
Welin, S1
Kozlovacki, G1
Oberg, K1
Granberg, D1
Saranga-Perry, V1
Morse, B1
Centeno, B1
Kvols, L1
Strosberg, J1
Tsang, LL1
Farmer, PB1
Gescher, A1
Slack, JA1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Phase II Study of Gamma Knife Radiosurgery and Temozolomide (Temodar) for Newly Diagnosed Brain Metastases[NCT00582075]Phase 225 participants (Actual)Interventional2002-07-31Completed
A Pilot Study Investigating Neoadjuvant Temozolomide-based Proton Chemoradiotherapy for High-Risk Soft Tissue Sarcomas[NCT00881595]Phase 20 participants (Actual)Interventional2009-02-28Withdrawn (stopped due to No patients accrued since study opened)
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Overall Survival

(NCT00582075)
Timeframe: 2 years

Interventionweeks (Median)
Radiosurgery 15-24 Gy + Adjuvant Temozolomide31

Percentage of Participants With Distant Brain Failure (DBF) at One Year

Patients developing distant brain failure (DBF) at one year. An approximation method was used to arrive at the reported percentage. (NCT00582075)
Timeframe: 1 years

Interventionpercentage of participants (Number)
Radiosurgery 15-24 Gy + Adjuvant Temozolomide37

Trials

1 trial available for temozolomide and Thymus Neoplasms

ArticleYear
Characterisation of urinary metabolites of temozolomide in humans and mice and evaluation of their cytotoxicity.
    Cancer chemotherapy and pharmacology, 1990, Volume: 26, Issue:6

    Topics: Animals; Antineoplastic Agents; Chromatography, High Pressure Liquid; Dacarbazine; Drug Evaluation;

1990
Characterisation of urinary metabolites of temozolomide in humans and mice and evaluation of their cytotoxicity.
    Cancer chemotherapy and pharmacology, 1990, Volume: 26, Issue:6

    Topics: Animals; Antineoplastic Agents; Chromatography, High Pressure Liquid; Dacarbazine; Drug Evaluation;

1990
Characterisation of urinary metabolites of temozolomide in humans and mice and evaluation of their cytotoxicity.
    Cancer chemotherapy and pharmacology, 1990, Volume: 26, Issue:6

    Topics: Animals; Antineoplastic Agents; Chromatography, High Pressure Liquid; Dacarbazine; Drug Evaluation;

1990
Characterisation of urinary metabolites of temozolomide in humans and mice and evaluation of their cytotoxicity.
    Cancer chemotherapy and pharmacology, 1990, Volume: 26, Issue:6

    Topics: Animals; Antineoplastic Agents; Chromatography, High Pressure Liquid; Dacarbazine; Drug Evaluation;

1990

Other Studies

2 other studies available for temozolomide and Thymus Neoplasms

ArticleYear
Treatment, prognostic markers and survival in thymic neuroendocrine tumours. a study from a single tertiary referral centre.
    Lung cancer (Amsterdam, Netherlands), 2013, Volume: 79, Issue:3

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Carcinoma, Neuroendo

2013
Treatment of metastatic neuroendocrine tumors of the thymus with capecitabine and temozolomide: a case series.
    Neuroendocrinology, 2013, Volume: 97, Issue:4

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Dacarbazine; Deoxycytidine; Flu

2013