temozolomide has been researched along with Pancytopenia in 8 studies
Pancytopenia: Deficiency of all three cell elements of the blood, erythrocytes, leukocytes and platelets.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We performed a phase 2 trial of neoadjuvant temozolomide (TMZ), followed by hypofractionated accelerated radiation therapy (HART) with concurrent TMZ, and adjuvant TMZ in patients with newly diagnosed glioblastoma to determine whether neoadjuvant TMZ would safely improve outcomes in this group of patients prior to subsequent cytotoxic therapy." | 9.24 | A Phase 2 Trial of Neoadjuvant Temozolomide Followed by Hypofractionated Accelerated Radiation Therapy With Concurrent and Adjuvant Temozolomide for Patients With Glioblastoma. ( Abdulkarim, B; Corredor, AG; Guiot, MC; Owen, S; Panet-Raymond, V; Petrecca, K; Shenouda, G; Souhami, L, 2017) |
| "To report pancytopenia caused by temozolomide, a second-generation alkylating agent." | 7.77 | Another cause of pancytopenia in a patient receiving temozolomide. ( Camci, C; Dirier, A; Kalender, ME; Pehlivan, Y; Sevinc, A; Turkbeyler, IH, 2011) |
| "We report a case of a 51-year-old woman with newly diagnosed glioblastoma multiforme (GBM) who was treated with surgery followed by the standard concomitant temozolomide (TMZ) and radiotherapy (RT)." | 7.75 | Prolonged and severe thrombocytopenia with pancytopenia induced by radiation-combined temozolomide therapy in a patient with newly diagnosed glioblastoma--analysis of O6-methylguanine-DNA methyltransferase status. ( Fujioka, Y; Homori, M; Kurita, H; Miyazaki, H; Nagane, M; Nozue, K; Shimizu, S; Shiokawa, Y; Waha, A, 2009) |
| "We report the case of a 30-year-old woman with glioblastoma multiforme (GBM) treated with surgery followed by concomitant Temozolomide (TMZ) and external beam radiation, which she tolerated well without any interruptions." | 7.74 | Unexpected case of aplastic anemia in a patient with glioblastoma multiforme treated with Temozolomide. ( Gujral, S; Jalali, R; Menon, H; Singh, P, 2007) |
| "Temozolomide may cause thrombocytopenia or neutropenia in 3-4% of glioblastoma patients, respectively." | 6.55 | MGMT gene variants, temozolomide myelotoxicity and glioma risk. A concise literature survey including an illustrative case. ( Altinoz, MA; Bolukbasi, FH; Ekmekci, CG; Elmaci, I; Sari, R; Sav, A; Yenmis, G, 2017) |
| "We performed a phase 2 trial of neoadjuvant temozolomide (TMZ), followed by hypofractionated accelerated radiation therapy (HART) with concurrent TMZ, and adjuvant TMZ in patients with newly diagnosed glioblastoma to determine whether neoadjuvant TMZ would safely improve outcomes in this group of patients prior to subsequent cytotoxic therapy." | 5.24 | A Phase 2 Trial of Neoadjuvant Temozolomide Followed by Hypofractionated Accelerated Radiation Therapy With Concurrent and Adjuvant Temozolomide for Patients With Glioblastoma. ( Abdulkarim, B; Corredor, AG; Guiot, MC; Owen, S; Panet-Raymond, V; Petrecca, K; Shenouda, G; Souhami, L, 2017) |
| "Temozolomide (TMZ) is an oral alkylating agent principally indicated for neurological malignancies including glioblastoma (GBM) and astrocytoma." | 5.12 | Temozolomide-induced aplastic anaemia: Case report and review of the literature. ( Gilbar, PJ; Mangos, HM; Pokharel, K, 2021) |
| "To report pancytopenia caused by temozolomide, a second-generation alkylating agent." | 3.77 | Another cause of pancytopenia in a patient receiving temozolomide. ( Camci, C; Dirier, A; Kalender, ME; Pehlivan, Y; Sevinc, A; Turkbeyler, IH, 2011) |
| "We report a case of a 51-year-old woman with newly diagnosed glioblastoma multiforme (GBM) who was treated with surgery followed by the standard concomitant temozolomide (TMZ) and radiotherapy (RT)." | 3.75 | Prolonged and severe thrombocytopenia with pancytopenia induced by radiation-combined temozolomide therapy in a patient with newly diagnosed glioblastoma--analysis of O6-methylguanine-DNA methyltransferase status. ( Fujioka, Y; Homori, M; Kurita, H; Miyazaki, H; Nagane, M; Nozue, K; Shimizu, S; Shiokawa, Y; Waha, A, 2009) |
| "We report the case of a 30-year-old woman with glioblastoma multiforme (GBM) treated with surgery followed by concomitant Temozolomide (TMZ) and external beam radiation, which she tolerated well without any interruptions." | 3.74 | Unexpected case of aplastic anemia in a patient with glioblastoma multiforme treated with Temozolomide. ( Gujral, S; Jalali, R; Menon, H; Singh, P, 2007) |
| "This is a report of a 53 year-old man with a glioblastoma multiforme (GBM) treated with an excessive dose of temozolomide (TMZ)." | 3.73 | Complications of a temozolomide overdose: a case report. ( Kiem, HP; Partap, S; Peterson, RA; Schuetze, S; Silber, JR; Spence, AM, 2006) |
| "Temozolomide may cause thrombocytopenia or neutropenia in 3-4% of glioblastoma patients, respectively." | 2.55 | MGMT gene variants, temozolomide myelotoxicity and glioma risk. A concise literature survey including an illustrative case. ( Altinoz, MA; Bolukbasi, FH; Ekmekci, CG; Elmaci, I; Sari, R; Sav, A; Yenmis, G, 2017) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (37.50) | 29.6817 |
| 2010's | 4 (50.00) | 24.3611 |
| 2020's | 1 (12.50) | 2.80 |
| Authors | Studies |
|---|---|
| Gilbar, PJ | 1 |
| Pokharel, K | 1 |
| Mangos, HM | 1 |
| Altinoz, MA | 1 |
| Elmaci, I | 1 |
| Bolukbasi, FH | 1 |
| Ekmekci, CG | 1 |
| Yenmis, G | 1 |
| Sari, R | 1 |
| Sav, A | 1 |
| Shenouda, G | 1 |
| Souhami, L | 1 |
| Petrecca, K | 1 |
| Owen, S | 1 |
| Panet-Raymond, V | 1 |
| Guiot, MC | 1 |
| Corredor, AG | 1 |
| Abdulkarim, B | 1 |
| Nagane, M | 1 |
| Nozue, K | 1 |
| Shimizu, S | 1 |
| Waha, A | 1 |
| Miyazaki, H | 1 |
| Kurita, H | 1 |
| Homori, M | 1 |
| Fujioka, Y | 1 |
| Shiokawa, Y | 1 |
| Łata, S | 1 |
| Molczyk, A | 1 |
| Pehlivan, Y | 1 |
| Sevinc, A | 1 |
| Turkbeyler, IH | 1 |
| Dirier, A | 1 |
| Kalender, ME | 1 |
| Camci, C | 1 |
| Spence, AM | 1 |
| Kiem, HP | 1 |
| Partap, S | 1 |
| Schuetze, S | 1 |
| Silber, JR | 1 |
| Peterson, RA | 1 |
| Jalali, R | 1 |
| Singh, P | 1 |
| Menon, H | 1 |
| Gujral, S | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| [NCT01702610] | 50 participants (Actual) | Interventional | 2008-12-31 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for temozolomide and Pancytopenia
| Article | Year |
|---|---|
Temozolomide-induced aplastic anaemia: Case report and review of the literature.
Topics: Aged; Anemia, Aplastic; Antineoplastic Agents, Alkylating; Brain Neoplasms; Female; Glioblastoma; Gr | 2021 |
MGMT gene variants, temozolomide myelotoxicity and glioma risk. A concise literature survey including an illustrative case.
Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; DNA Modification Methylases; DNA Re | 2017 |
1 trial available for temozolomide and Pancytopenia
| Article | Year |
|---|---|
A Phase 2 Trial of Neoadjuvant Temozolomide Followed by Hypofractionated Accelerated Radiation Therapy With Concurrent and Adjuvant Temozolomide for Patients With Glioblastoma.
Topics: Adult; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Chemotherapy, Adjuvant | 2017 |
5 other studies available for temozolomide and Pancytopenia
| Article | Year |
|---|---|
Prolonged and severe thrombocytopenia with pancytopenia induced by radiation-combined temozolomide therapy in a patient with newly diagnosed glioblastoma--analysis of O6-methylguanine-DNA methyltransferase status.
Topics: Antineoplastic Agents, Alkylating; Base Sequence; Blotting, Western; Brain Neoplasms; Combined Modal | 2009 |
[Side effects of temozolomide treatment in patient with glioblastoma multiforme--case study].
Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant; Dacarbazine; Female; Gli | 2010 |
Another cause of pancytopenia in a patient receiving temozolomide.
Topics: Antineoplastic Agents, Alkylating; Dacarbazine; Female; Glioblastoma; Humans; Pancytopenia; Risk Fac | 2011 |
Complications of a temozolomide overdose: a case report.
Topics: Antineoplastic Agents, Alkylating; Bacterial Infections; Brain Neoplasms; Combined Modality Therapy; | 2006 |
Unexpected case of aplastic anemia in a patient with glioblastoma multiforme treated with Temozolomide.
Topics: Adult; Anemia, Aplastic; Antineoplastic Agents, Alkylating; Blood Cell Count; Bone Marrow; Brain Neo | 2007 |