temozolomide has been researched along with Nelson Syndrome in 6 studies
Nelson Syndrome: A syndrome characterized by HYPERPIGMENTATION, enlarging pituitary mass, visual defects secondary to compression of the OPTIC CHIASM, and elevated serum ACTH. It is caused by the expansion of an underlying ACTH-SECRETING PITUITARY ADENOMA that grows in the absence of feedback inhibition by adrenal CORTICOSTEROIDS, usually after ADRENALECTOMY.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Temozolomide has been used in patients with aggressive Nelson's with no consistent results." | 2.82 | Management of Nelson's Syndrome. ( Fountas, A; Karavitaki, N, 2022) |
| "Cushing's disease is a syndromic pathological condition caused by adrenocorticotropic hormone (ACTH)-secreting pituitary adenomas (ACTHomas) mediated by hypercortisolemia." | 2.72 | Aggressive Cushing's Disease: Molecular Pathology and Its Therapeutic Approach. ( Fukuoka, H; Nakao, T; Ogawa, W; Yamamoto, M, 2021) |
| "Treatment with temozolomide resulted in a significant improvement in symptoms, a reduction of plasma ACTH to 389 pmol/l and regression of tumour on magnetic resonance imaging scan after four cycles of treatment." | 1.35 | Treatment of Nelson's syndrome with temozolomide. ( Alusi, G; Berney, DM; Drake, WM; Evanson, J; Kovacs, K; Monson, JP; Moyes, VJ; Plowman, PN; Sabin, HI, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (16.67) | 29.6817 |
| 2010's | 2 (33.33) | 24.3611 |
| 2020's | 3 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Mirallas, O | 1 |
| Filippi-Arriaga, F | 1 |
| Hernandez Hernandez, I | 1 |
| Aubanell, A | 1 |
| Chaachou, A | 1 |
| Garcia-Alvarez, A | 1 |
| Hernando, J | 1 |
| MartÃnez-Saez, E | 1 |
| Biagetti, B | 1 |
| Capdevila, J | 1 |
| Fountas, A | 1 |
| Karavitaki, N | 2 |
| Yamamoto, M | 1 |
| Nakao, T | 1 |
| Ogawa, W | 1 |
| Fukuoka, H | 1 |
| Moyes, VJ | 2 |
| Alusi, G | 1 |
| Sabin, HI | 1 |
| Evanson, J | 1 |
| Berney, DM | 1 |
| Kovacs, K | 2 |
| Monson, JP | 1 |
| Plowman, PN | 1 |
| Drake, WM | 2 |
| Barber, TM | 1 |
| Adams, E | 1 |
| Ansorge, O | 1 |
| Byrne, JV | 1 |
| Wass, JA | 1 |
| Salehi, F | 1 |
| Scheithauer, BW | 1 |
| Syro, LV | 1 |
| Manoranjan, B | 1 |
| Sharma, S | 1 |
| Horvath, E | 1 |
3 reviews available for temozolomide and Nelson Syndrome
| Article | Year |
|---|---|
Management of Nelson's Syndrome.
Topics: Adrenalectomy; Adrenocorticotropic Hormone; Humans; Nelson Syndrome; Temozolomide | 2022 |
Aggressive Cushing's Disease: Molecular Pathology and Its Therapeutic Approach.
Topics: ACTH-Secreting Pituitary Adenoma; Adenoma; Adrenocorticotropic Hormone; Carcinoma; Dopamine Agonists | 2021 |
Nelson's syndrome.
Topics: Adrenocorticotropic Hormone; Alkylating Agents; Dacarbazine; Humans; Magnetic Resonance Imaging; Nel | 2010 |
3 other studies available for temozolomide and Nelson Syndrome
| Article | Year |
|---|---|
Aggressive Pituitary Macroadenoma Treated With Capecitabine and Temozolomide Chemotherapy Combination in a Patient With Nelson's Syndrome: A Case Report.
Topics: Adenoma; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Humans; Male; Middle Aged; Ne | 2021 |
Treatment of Nelson's syndrome with temozolomide.
Topics: Adrenocorticotropic Hormone; Antineoplastic Agents, Alkylating; Dacarbazine; Female; Humans; Middle | 2009 |
Low immunohistochemical expression of MGMT in ACTH secreting pituitary tumors of patients with Nelson syndrome.
Topics: ACTH-Secreting Pituitary Adenoma; Adenoma; Aged; Antineoplastic Agents, Alkylating; Dacarbazine; DNA | 2010 |