Page last updated: 2024-11-04

temozolomide and Meningeal Neoplasms

temozolomide has been researched along with Meningeal Neoplasms in 40 studies

Meningeal Neoplasms: Benign and malignant neoplastic processes that arise from or secondarily involve the meningeal coverings of the brain and spinal cord.

Research Excerpts

ExcerptRelevanceReference
"Based on our findings in two paediatric patients, temozolomide may be a useful agent in the management of progressive recurrent low grade spinal cord astrocytomas."9.12Role of temozolomide in spinal cord low grade astrocytomas: results in two paediatric patients. ( Abboud, MR; Al Kutoubi, AO; Alaraj, AM; Chamoun, RB; Haddad, GF, 2006)
"A prospective Phase II study of temozolomide (TMZ) was conducted in 16 patients with refractory meningioma."9.11Temozolomide for treatment-resistant recurrent meningioma. ( Chamberlain, MC; Groshen, S; Tsao-Wei, DD, 2004)
"Temozolomide (TMZ) is a DNA alkylating agent that appears to have a radiosensitizing effect when used in combination with RT and may be worthwhile in meningioma treatment."5.72Concomitant Temozolomide plus radiotherapy for high-grade and recurrent meningioma: a retrospective chart review. ( Belanger, K; Damek, D; Lillehei, KO; Ormond, DR; Ung, TH, 2022)
"High-grade meningioma is an aggressive type of brain cancer that is often recalcitrant to surgery and radiotherapy, leading to poor overall survival."5.62Evaluation of a procaspase-3 activator with hydroxyurea or temozolomide against high-grade meningioma in cell culture and canine cancer patients. ( Basuli, F; Berry, MR; Botham, RC; Chen, Z; Daniel, GB; Fan, TM; Hergenrother, PJ; Huang, S; Joslyn, SK; LeBlanc, AK; Rao, J; Riggins, GJ; Rossmeisl, JH; Tonogai, EJ; Zhang, X, 2021)
"The diagnosis of an anaplastic oligodendroglioma (WHO grade 3) was made on pathological examination."5.35Primary leptomeningeal anaplastic oligodendroglioma with a 1p36-19q13 deletion: report of a unique case successfully treated with Temozolomide. ( Chaskis, C; Michotte, A; Neyns, B; Sadones, J; Veld, PI, 2009)
" After irradiation of the symptomatic sites, intrathecal liposomal Ara-C every 2-4 weeks was combined with temozolomide 100 mg/m(2) day 1-5/7."5.35Neoplastic meningitis from breast cancer: feasibility and activity of long-term intrathecal liposomal Ara-C combined with dose-dense temozolomide. ( Buhk, JH; Hoffmann, AL; Strik, H, 2009)
"Based on our findings in two paediatric patients, temozolomide may be a useful agent in the management of progressive recurrent low grade spinal cord astrocytomas."5.12Role of temozolomide in spinal cord low grade astrocytomas: results in two paediatric patients. ( Abboud, MR; Al Kutoubi, AO; Alaraj, AM; Chamoun, RB; Haddad, GF, 2006)
"A prospective Phase II study of temozolomide (TMZ) was conducted in 16 patients with refractory meningioma."5.11Temozolomide for treatment-resistant recurrent meningioma. ( Chamberlain, MC; Groshen, S; Tsao-Wei, DD, 2004)
" Cases from June 2006 through October 2016 were identified for patients receiving bevacizumab and temozolomide for locally advanced, recurrent or metastatic solitary fibrous tumour or hemangiopericytoma, which is sometimes used to describe tumours arising from the meninges."3.91Efficacy of bevacizumab and temozolomide therapy in locally advanced, recurrent, and metastatic malignant solitary fibrous tumour: A population-based analysis. ( de Lemos, ML; Kang, I; Schaff, K, 2019)
"The LMD source was breast cancer (53 %) and non-small-cell lung cancer (37 %)."2.77Phase II trial of temozolomide for leptomeningeal metastases in patients with solid tumors. ( Balañá, C; Bruna, J; Chacón, I; Gil, M; Langa, JM; Martín, M; Segura, PP, 2012)
"Temozolomide (TMZ) is a DNA alkylating agent that appears to have a radiosensitizing effect when used in combination with RT and may be worthwhile in meningioma treatment."1.72Concomitant Temozolomide plus radiotherapy for high-grade and recurrent meningioma: a retrospective chart review. ( Belanger, K; Damek, D; Lillehei, KO; Ormond, DR; Ung, TH, 2022)
"Glioblastoma multiforme is one of the most common malignant types of tumor arising from the central nervous system known for its devastating intracranial progress and dismal prognosis."1.62FDG PET/CT in Recurrent Glioblastoma Multiforme With Leptomeningeal and Diffuse Spinal Cord Metastasis. ( Malik, D, 2021)
"High-grade meningioma is an aggressive type of brain cancer that is often recalcitrant to surgery and radiotherapy, leading to poor overall survival."1.62Evaluation of a procaspase-3 activator with hydroxyurea or temozolomide against high-grade meningioma in cell culture and canine cancer patients. ( Basuli, F; Berry, MR; Botham, RC; Chen, Z; Daniel, GB; Fan, TM; Hergenrother, PJ; Huang, S; Joslyn, SK; LeBlanc, AK; Rao, J; Riggins, GJ; Rossmeisl, JH; Tonogai, EJ; Zhang, X, 2021)
"Compared with pilocytic astrocytoma, PMA is more aggressive, has a higher rate of local recurrence, and often disseminates to the leptomeninges."1.38Successful treatment of leptomeningeal gliomatosis of pilomyxoid astrocytoma after failed frontline chemotherapy. ( Bouffet, E; Maeda, M; Morioka, M; Sawamura, Y; Sugita, Y; Terasaki, M, 2012)
"Meningiomas are usually cured by surgical resection."1.35Methylation status of MGMT gene promoter in meningiomas. ( Cairncross, G; de Robles, P; Easaw, J; Forsyth, P; Hamilton, M; Kalra, S; Magliocco, T; McIntyre, J; Roldán, G, 2008)
"The diagnosis of an anaplastic oligodendroglioma (WHO grade 3) was made on pathological examination."1.35Primary leptomeningeal anaplastic oligodendroglioma with a 1p36-19q13 deletion: report of a unique case successfully treated with Temozolomide. ( Chaskis, C; Michotte, A; Neyns, B; Sadones, J; Veld, PI, 2009)
" After irradiation of the symptomatic sites, intrathecal liposomal Ara-C every 2-4 weeks was combined with temozolomide 100 mg/m(2) day 1-5/7."1.35Neoplastic meningitis from breast cancer: feasibility and activity of long-term intrathecal liposomal Ara-C combined with dose-dense temozolomide. ( Buhk, JH; Hoffmann, AL; Strik, H, 2009)
"Thus, we describe a malignant meningioma model system that will be useful for investigating the biology of meningiomas and for preclinical assessment of therapeutic agents."1.35An orthotopic skull base model of malignant meningioma. ( Baia, GS; Dinca, EB; James, CD; Kimura, ET; Lal, A; McDermott, MW; Ozawa, T; VandenBerg, SR, 2008)

Research

Studies (40)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (2.50)18.2507
2000's15 (37.50)29.6817
2010's20 (50.00)24.3611
2020's4 (10.00)2.80

Authors

AuthorsStudies
Gonda, T1
Wakabayashi, K1
Haraguchi, K1
Arai, Y1
Oyama, H1
Belanger, K1
Ung, TH1
Damek, D1
Lillehei, KO1
Ormond, DR1
Malik, D1
Tonogai, EJ1
Huang, S1
Botham, RC1
Berry, MR1
Joslyn, SK1
Daniel, GB1
Chen, Z1
Rao, J1
Zhang, X1
Basuli, F1
Rossmeisl, JH1
Riggins, GJ1
LeBlanc, AK1
Fan, TM1
Hergenrother, PJ1
van der Vlist, A1
Snijders, TJ1
Stades, AME1
Spliet, WGM1
De Vos, FYFL1
de Lemos, ML1
Kang, I1
Schaff, K1
Schwartz, C1
Romagna, A1
Machegger, L1
Weiss, L1
Huemer, F1
Fastner, G1
Kleindienst, W1
Weis, S1
Greil, R1
Winkler, PA1
Autran, D1
Barrie, M1
Matta, M1
Monserrat, C1
Campello, C1
Petrirena, G1
Boucard, C1
Padovani, L1
Loundou, A1
Appay, R1
Graillon, T1
Dufour, H1
Figarella-Branger, D1
Chinot, O1
Tabouret, E1
Aghajan, Y1
Malicki, DM1
Levy, ML1
Crawford, JR1
Grah, JJ1
Katalinic, D1
Stern-Padovan, R1
Paladino, J1
Santek, F1
Juretic, A1
Zarkovic, K1
Plestina, S1
Supe, M1
Kuo, LT1
Tsai, SY1
Yang, CY1
Lin, LW1
Yamasaki, K1
Yokogami, K1
Ohta, H1
Yamashita, S1
Uehara, H1
Sato, Y1
Takeshima, H1
Wilisch-Neumann, A1
Pachow, D1
Wallesch, M1
Petermann, A1
Böhmer, FD1
Kirches, E1
Mawrin, C1
Kong, X1
Wang, Y1
Liu, S1
Chen, K1
Zhou, Q1
Yan, C1
He, H1
Gao, J1
Guan, J1
Yang, Y1
Li, Y1
Xing, B1
Wang, R1
Ma, W1
He, J1
Liu, C1
Wang, B1
Li, N1
Zuo, G1
Gao, D1
Pellerino, A1
Soffietti, R2
Rudà, R2
Sahuc, P1
Joubert, C1
Nguyen, AT1
Fouet, B1
Wybrecht, D1
Faivre, A1
Alla, P1
Dagain, A1
de Robles, P1
McIntyre, J1
Kalra, S1
Roldán, G1
Cairncross, G1
Forsyth, P1
Magliocco, T1
Hamilton, M1
Easaw, J1
Jicha, GA1
Glantz, J1
Clarke, MJ1
Lehwald, LM1
Russo, DP1
Giannini, C1
Wald, JT1
Uhm, J1
Kumar, N1
Aksamit, AJ1
Wetmore, CJ1
Walker, JG1
Subbiah, V1
Wolff, JE1
Michotte, A1
Chaskis, C1
Sadones, J1
Veld, PI1
Neyns, B1
Passarin, MG1
Moretto, G1
Musso, AM1
Ottaviani, S1
Masotto, B1
Ghimenton, C1
Iuzzolino, P1
Buffone, E1
Vattemi, E1
Pedersini, R1
Hoffmann, AL1
Buhk, JH1
Strik, H1
Zauderer, M1
Krug, LM1
Pietanza, MC1
O'Rourke, D1
Schaefer, N1
Rasch, K1
Moehlenbruch, M1
Urbach, H1
Stuplich, M1
Blasius, E1
Scheffler, B1
Herrlinger, U1
Glas, M1
Hansen, N1
Wittig, A1
Hense, J1
Kastrup, O1
Gizewski, ER1
Van de Nes, JA1
Terasaki, M1
Bouffet, E1
Maeda, M1
Sugita, Y1
Sawamura, Y1
Morioka, M1
Segura, PP1
Gil, M1
Balañá, C1
Chacón, I1
Langa, JM1
Martín, M1
Bruna, J1
Salmaggi, A1
Silvani, A1
Eoli, M1
Lamperti, E1
Boiardi, A1
Chamberlain, MC1
Tsao-Wei, DD1
Groshen, S1
Wong, ET1
Franceschi, E1
Cavallo, G1
Scopece, L1
Esposti, RD1
Paioli, G1
Paioli, A1
Palmerini, E1
Foschini, MP1
Marliani, AF1
Crinò, L1
Koch, HJ1
Roeber, S1
Zimmermann, UW1
Schäfer, C1
Villarrubia, V1
Kuchelmeister, K1
Schachenmayr, W1
Bogdahn, U1
Steinbrecher, A1
Chamoun, RB1
Alaraj, AM1
Al Kutoubi, AO1
Abboud, MR1
Haddad, GF1
Enting, RH1
van der Graaf, WT1
Kros, JM1
Heesters, M1
Metzemaekers, J1
den Dunnen, W1
Ku, GY1
Krol, G1
Ilson, DH1
Baia, GS1
Dinca, EB1
Ozawa, T1
Kimura, ET1
McDermott, MW1
James, CD1
VandenBerg, SR1
Lal, A1
Sampson, JH1
Archer, GE1
Villavicencio, AT1
McLendon, RE1
Friedman, AH1
Bishop, WR1
Bigner, DD1
Friedman, HS1
Rao, RD1
Robins, HI1
Mehta, MP1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Phase 2a Study of the Addition of Temozolomide to a Standard Conditioning Regimen for Autologous Stem Cell Transplantation in Relapsed and Refractory Central Nervous System (CNS) Lymphoma[NCT01235793]Phase 211 participants (Actual)Interventional2010-10-14Terminated (stopped due to The clinical trial was terminated due to poor enrollment)
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Safest Dose of Temozolomide for the DRBEAT Regimen

Safety will be assessed using a dose escalation design for temozolomide's use to determine the target dose and also to evaluate any and all acute treatment related toxicities. During the course of patient follow up and therapy, toxicities will be evaluated, particularly as the investigators will be determining the target dose of temozolomide. One of the major criteria for dose limiting toxicity for the study will be any Grade 3 or 4 nonhematologic toxicity from a list of commonly expected toxicities associated with autologous transplantation and temozolomide. (NCT01235793)
Timeframe: One Year

Interventiondose in mg/m^2 (Number)
DRBEAT Regimen773.25

One-year Progression-free Survival and Overall Survival

"Efficacy of the DRBEAT Regimen will be assessed by analysis of~one-year progression-free survival (PFS), defined as the time interval from maximal response from therapy to tumor regrowth, progression*, or death, (*Progression is defined as meeting the response criteria listed in Table 4: Response Criteria for Primary Central Nervous System Lymphoma according to Abrey LE, Batchelor TT, Ferreri AJM et al.)~and~Overall survival, defined as the time interval between the date of transplant and the date of death from any cause." (NCT01235793)
Timeframe: (1) One Year (2) Until date of death from any cause, assessed up to 2 years

InterventionDays (Median)
Progression Free SurvivalOverall Survival
DRBEAT Regimen132564

Reviews

1 review available for temozolomide and Meningeal Neoplasms

ArticleYear
Glioblastoma Secondary to Meningioma: A Case Report and Literature Review.
    World neurosurgery, 2017, Volume: 98

    Topics: Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Glial Fibrillary Acidic Prote

2017

Trials

4 trials available for temozolomide and Meningeal Neoplasms

ArticleYear
Phase II trial of temozolomide for leptomeningeal metastases in patients with solid tumors.
    Journal of neuro-oncology, 2012, Volume: 109, Issue:1

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Breast Neoplasms; Carcinoma, Non-Small-Cell Lung; Da

2012
Temozolomide and cisplatin in the treatment of leptomeningeal metastatic involvement from melanoma: a case report.
    Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 2002, Volume: 23, Issue:5

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Dacarbazine; Humans; Magnetic Reso

2002
Temozolomide for treatment-resistant recurrent meningioma.
    Neurology, 2004, Apr-13, Volume: 62, Issue:7

    Topics: Administration, Oral; Aged; Antineoplastic Agents, Alkylating; Dacarbazine; Dexamethasone; Disease P

2004
Role of temozolomide in spinal cord low grade astrocytomas: results in two paediatric patients.
    Acta neurochirurgica, 2006, Volume: 148, Issue:2

    Topics: Adolescent; Antineoplastic Agents, Alkylating; Astrocytoma; Child; Dacarbazine; Disease Progression;

2006

Other Studies

35 other studies available for temozolomide and Meningeal Neoplasms

ArticleYear
[Primary leptomeningeal gliomatosis treated with temozolomide: a case report].
    Rinsho shinkeigaku = Clinical neurology, 2021, Dec-22, Volume: 61, Issue:12

    Topics: Adult; Humans; Magnetic Resonance Imaging; Male; Meningeal Neoplasms; Meninges; Neoplasms, Neuroepit

2021
Concomitant Temozolomide plus radiotherapy for high-grade and recurrent meningioma: a retrospective chart review.
    BMC cancer, 2022, Apr-07, Volume: 22, Issue:1

    Topics: Brain Neoplasms; Child; Humans; Meningeal Neoplasms; Meningioma; Neoplasm Recurrence, Local; Retrosp

2022
FDG PET/CT in Recurrent Glioblastoma Multiforme With Leptomeningeal and Diffuse Spinal Cord Metastasis.
    Clinical nuclear medicine, 2021, Feb-01, Volume: 46, Issue:2

    Topics: Adult; Brain Neoplasms; Female; Fluorodeoxyglucose F18; Glioblastoma; Humans; Meningeal Neoplasms; P

2021
Evaluation of a procaspase-3 activator with hydroxyurea or temozolomide against high-grade meningioma in cell culture and canine cancer patients.
    Neuro-oncology, 2021, 10-01, Volume: 23, Issue:10

    Topics: Animals; Apoptosis; Caspase 3; Cell Culture Techniques; Cell Line, Tumor; Dogs; Humans; Hydroxyurea;

2021
Successful treatment of leptomeningeally metastasised pituitary carcinoma with temozolomide.
    The Netherlands journal of medicine, 2017, Volume: 75, Issue:10

    Topics: Aged; Antineoplastic Agents, Alkylating; Dacarbazine; Humans; Male; Meningeal Neoplasms; Pituitary N

2017
Efficacy of bevacizumab and temozolomide therapy in locally advanced, recurrent, and metastatic malignant solitary fibrous tumour: A population-based analysis.
    Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners, 2019, Volume: 25, Issue:6

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Female; Hemangiopericytoma

2019
Extensive Leptomeningeal Intracranial and Spinal Metastases in a Patient with a Supratentorial Glioblastoma Multiforme, IDH-Wildtype.
    World neurosurgery, 2018, Volume: 120

    Topics: Antibodies, Monoclonal, Humanized; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Immunol

2018
Leptomeningeal Gliomatosis: A Single Institution Study of 31 Patients.
    Anticancer research, 2019, Volume: 39, Issue:2

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carmustine; Combined M

2019
Atypical anaplastic astrocytoma with unique molecular features and diffuse leptomeningeal spread in a child with long-term survival.
    BMJ case reports, 2019, Feb-13, Volume: 12, Issue:2

    Topics: Astrocytoma; Brain; Chemoradiotherapy; Child; Gene Amplification; High-Throughput Nucleotide Sequenc

2019
Leptomeningeal and intramedullary metastases of glioblastoma multiforme in a patient reoperated during adjuvant radiochemotherapy.
    World journal of surgical oncology, 2013, Mar-05, Volume: 11

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy, Adjuvant; Combined Modality T

2013
Meningeal seeding from glioblastoma multiforme treated with radiotherapy and temozolomide.
    Asian journal of surgery, 2017, Volume: 40, Issue:1

    Topics: Adult; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy, Adjuvant; Dacarbazine;

2017
Case of primary diffuse leptomeningeal gliomatosis.
    Brain tumor pathology, 2014, Volume: 31, Issue:3

    Topics: Antineoplastic Agents, Alkylating; Dacarbazine; DNA Modification Methylases; DNA Repair Enzymes; Fat

2014
Re-evaluation of cytostatic therapies for meningiomas in vitro.
    Journal of cancer research and clinical oncology, 2014, Volume: 140, Issue:8

    Topics: Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Dacarbazine; DNA Methylation; DNA Modification M

2014
Brain Stem and Entire Spinal Leptomeningeal Dissemination of Supratentorial Glioblastoma Multiforme in a Patient during Postoperative Radiochemotherapy: Case Report and Review of the Literatures.
    Medicine, 2015, Volume: 94, Issue:24

    Topics: Adult; Antineoplastic Agents; Brain Neoplasms; Brain Stem Neoplasms; Chemoradiotherapy; Cisplatin; D

2015
HMGN5 blockade by siRNA enhances apoptosis, suppresses invasion and increases chemosensitivity to temozolomide in meningiomas.
    International journal of oncology, 2015, Volume: 47, Issue:4

    Topics: Aged; Antineoplastic Agents; Apoptosis; Blotting, Western; Dacarbazine; Drug Resistance, Neoplasm; F

2015
Temozolomide for recurrent meningiomas: a case-report with unexpected clinical and radiological response.
    Journal of neuro-oncology, 2016, Volume: 127, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Dacarbazine; Humans; Magnetic Resonance Imaging; Male; Meningeal

2016
Methylation status of MGMT gene promoter in meningiomas.
    Cancer genetics and cytogenetics, 2008, Volume: 187, Issue:1

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Dacarbazine; DNA Methylation; DNA Modification Methy

2008
Primary diffuse leptomeningeal gliomatosis.
    European neurology, 2009, Volume: 62, Issue:1

    Topics: Adolescent; Antineoplastic Agents, Alkylating; Brain; Dacarbazine; Diagnosis, Differential; Humans;

2009
Diagnosis and management of leptomeningeal disease.
    Clinical journal of oncology nursing, 2009, Volume: 13, Issue:4

    Topics: Adult; Antineoplastic Agents, Alkylating; Benzenesulfonates; Dacarbazine; Female; Humans; Meningeal

2009
Rapid response to therapy of neurocutaneous melanosis with leptomeningeal melanoma.
    Pediatric blood & cancer, 2010, Volume: 54, Issue:1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Benzenesulfonates; Child, Preschool; Cyclophosphamid

2010
Primary leptomeningeal anaplastic oligodendroglioma with a 1p36-19q13 deletion: report of a unique case successfully treated with Temozolomide.
    Journal of the neurological sciences, 2009, Dec-15, Volume: 287, Issue:1-2

    Topics: Antineoplastic Agents, Alkylating; Arachnoid; Brain; Chromosomes, Human, Pair 1; Chromosomes, Human,

2009
Intrathecal liposomal cytarabine in combination with temozolomide in low-grade oligoastrocytoma with leptomeningeal dissemination.
    Journal of neuro-oncology, 2010, Volume: 97, Issue:3

    Topics: Adult; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Cytar

2010
Neoplastic meningitis from breast cancer: feasibility and activity of long-term intrathecal liposomal Ara-C combined with dose-dense temozolomide.
    Anticancer research, 2009, Volume: 29, Issue:12

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Breast Neoplasms; Combined M

2009
Leptomeningeal metastases from small cell lung cancer responsive to temozolomide therapy.
    Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer, 2010, Volume: 5, Issue:10

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Female; Humans; Lung Neoplasms; Mal

2010
Leptomeningeal melanomatosis: stabilization of disease due to radiation, temozolomide and intrathecal liposomal cytarabine.
    Acta oncologica (Stockholm, Sweden), 2011, Volume: 50, Issue:8

    Topics: Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Cytarabine; Dacarbazine;

2011
Long survival of primary diffuse leptomeningeal gliomatosis following radiotherapy and temozolomide: case report and literature review.
    European journal of medical research, 2011, Sep-12, Volume: 16, Issue:9

    Topics: Antineoplastic Agents, Alkylating; Chemoradiotherapy; Dacarbazine; Humans; Male; Meningeal Neoplasms

2011
Successful treatment of leptomeningeal gliomatosis of pilomyxoid astrocytoma after failed frontline chemotherapy.
    The neurologist, 2012, Volume: 18, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Astrocytoma; Child, Preschool; Combined Modality Therapy; Cranial

2012
Salvage therapy for primary CNS lymphoma with a combination of rituximab and temozolomide.
    Neurology, 2005, Mar-08, Volume: 64, Issue:5

    Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Agents; Antineoplasti

2005
Temozolomide-induced partial response in a patient with primary diffuse leptomeningeal gliomatosis.
    Journal of neuro-oncology, 2005, Volume: 73, Issue:3

    Topics: Adult; Antineoplastic Agents, Alkylating; Dacarbazine; Female; Glioma; Humans; Magnetic Resonance Im

2005
[Spinal and cerebral leptomeningeal seeding from a melanocytoma of the cerebello-pontine angle].
    Wiener medizinische Wochenschrift (1946), 2005, Volume: 155, Issue:15-16

    Topics: Administration, Oral; Adult; Antineoplastic Agents, Alkylating; Arachnoid; Cerebellar Diseases; Cere

2005
Radiotherapy plus concomitant and adjuvant temozolomide for leptomeningeal pilomyxoid astrocytoma: a case study.
    Journal of neuro-oncology, 2006, Volume: 80, Issue:1

    Topics: Adult; Antineoplastic Agents, Alkylating; Astrocytoma; Cerebral Ventricle Neoplasms; Chemotherapy, A

2006
Successful treatment of leptomeningeal disease in colorectal cancer with a regimen of bevacizumab, temozolomide, and irinotecan.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2007, May-01, Volume: 25, Issue:13

    Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Prot

2007
An orthotopic skull base model of malignant meningioma.
    Brain pathology (Zurich, Switzerland), 2008, Volume: 18, Issue:2

    Topics: Animals; Antineoplastic Agents, Alkylating; Cell Line, Tumor; Dacarbazine; Disease Models, Animal; D

2008
Treatment of neoplastic meningitis with intrathecal temozolomide.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 1999, Volume: 5, Issue:5

    Topics: Animals; Antineoplastic Agents, Alkylating; Dacarbazine; Drug Screening Assays, Antitumor; Humans; M

1999
Late recurrence of a primitive neuro-ectodermal tumor.
    Oncology, 2001, Volume: 61, Issue:3

    Topics: Adult; Alkaline Phosphatase; Antineoplastic Agents, Alkylating; Biomarkers, Tumor; Cerebellar Neopla

2001