Page last updated: 2024-11-04

temozolomide and Lymphoma, Non-Hodgkin

temozolomide has been researched along with Lymphoma, Non-Hodgkin in 16 studies

Lymphoma, Non-Hodgkin: Any of a group of malignant tumors of lymphoid tissue that differ from HODGKIN DISEASE, being more heterogeneous with respect to malignant cell lineage, clinical course, prognosis, and therapy. The only common feature among these tumors is the absence of giant REED-STERNBERG CELLS, a characteristic of Hodgkin's disease.

Research Excerpts

ExcerptRelevanceReference
"Glioblastoma multiforme is an astrocyte-derived tumour representing the most aggressive primary brain malignancy."5.51Temozolomide-induced aplastic anaemia and incidental low-grade B-cell non-Hodgkin lymphoma in a geriatric patient with glioblastoma multiforme. ( Aleixo, GF; Batalini, F; Drews, R; Kaufmann, MR, 2019)
"Temozolomide (TMZ) is an oral alkylating agent with significant activity against glioblastoma multiforme (GBM) and melanoma."3.75Non-Hodgkin lymphoma following temozolomide. ( Das, P; Dwary, A; Goyal, S; Gupta, D; Mohanti, BK; Muzumder, S; Sharma, A; Thulkar, S, 2009)
"Glioblastoma multiforme is an astrocyte-derived tumour representing the most aggressive primary brain malignancy."1.51Temozolomide-induced aplastic anaemia and incidental low-grade B-cell non-Hodgkin lymphoma in a geriatric patient with glioblastoma multiforme. ( Aleixo, GF; Batalini, F; Drews, R; Kaufmann, MR, 2019)
"Temozolomide (TMZ) has established antineoplastic activity in the central nervous system in other disease states, with a favorable toxicity profile."1.51Temozolomide as a Single Agent Maintenance Therapy in Elderly Patients With Primary CNS Lymphoma. ( Brenner, A; Butler, MJ; Faivre, G; Le, I, 2019)
"The temozolomide was stopped and the lymphoma was successfully treated with chemotherapy."1.38Non-Hodgkin's lymphoma in a patient on treatment with temozolomide. ( Otty, Z; Sabesan, S, 2012)

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (6.25)18.2507
2000's4 (25.00)29.6817
2010's9 (56.25)24.3611
2020's2 (12.50)2.80

Authors

AuthorsStudies
Kaulen, LD1
Baehring, JM1
Wang, H1
Wang, M1
Wei, J1
Wang, L1
Mao, L1
Jin, J1
Zheng, J1
Wang, C1
Liu, F1
Li, X1
Xu, X1
Chen, K1
Wu, H1
Wang, Y2
Yang, S1
Wang, K1
Chen, C1
Sun, P1
Cui, J1
Yan, S1
Chen, H1
Xia, Y1
Bi, X1
Liu, P1
Yang, H1
Nie, M1
Zhang, XW1
Jiang, W1
Li, ZM1
Batalini, F1
Kaufmann, MR1
Aleixo, GF1
Drews, R1
Faivre, G1
Butler, MJ1
Le, I1
Brenner, A1
Pulczynski, EJ1
Kuittinen, O1
Erlanson, M1
Hagberg, H1
Fosså, A1
Eriksson, M1
Nordstrøm, M1
Østenstad, B1
Fluge, Ø1
Leppä, S1
Fiirgaard, B1
Bersvendsen, H1
Fagerli, UM1
Broes, K1
Van Ginderachter, L1
Joosens, E2
Maes, A1
Theunissen, K1
Schepers, S1
Deben, K1
Claes, J1
Mebis, J1
Cox, T1
Neyns, B1
Cordera, S1
Pouratian, N1
Nader, P1
Sharma, A1
Gupta, D1
Mohanti, BK1
Thulkar, S1
Dwary, A1
Goyal, S1
Muzumder, S1
Das, P1
Otty, Z1
Sabesan, S1
Osmani, AH1
Masood, N1
Herrlinger, U1
Hebart, H1
Kanz, L1
Dichgans, J1
Weller, M1
Woll, PJ1
Crowther, D1
Johnson, PW1
Soukop, M1
Harper, PG1
Harris, M1
Brampton, MH1
Newlands, ES1
Reni, M1
Ferreri, AJ1
Landoni, C1
Villa, E1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Immunochemotherapy in Primary Central Nervous System Lymphoma With Rituximab, HD-MTX, HD-Ara C, Cyclophosphamide, Ifosfamide, Vincristine, Vindesine, Temozolomide and DepoCyte Induction Followed by Maintenance Treatment in Elderly Patients With Temozolomi[NCT01458730]Phase 266 participants (Actual)Interventional2007-05-31Completed
Phase II Study of Gamma Knife Radiosurgery and Temozolomide (Temodar) for Newly Diagnosed Brain Metastases[NCT00582075]Phase 225 participants (Actual)Interventional2002-07-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Overall Survival

(NCT00582075)
Timeframe: 2 years

Interventionweeks (Median)
Radiosurgery 15-24 Gy + Adjuvant Temozolomide31

Percentage of Participants With Distant Brain Failure (DBF) at One Year

Patients developing distant brain failure (DBF) at one year. An approximation method was used to arrive at the reported percentage. (NCT00582075)
Timeframe: 1 years

Interventionpercentage of participants (Number)
Radiosurgery 15-24 Gy + Adjuvant Temozolomide37

Reviews

1 review available for temozolomide and Lymphoma, Non-Hodgkin

ArticleYear
Treatment Options for Recurrent Primary CNS Lymphoma.
    Current treatment options in oncology, 2022, Volume: 23, Issue:11

    Topics: Agammaglobulinaemia Tyrosine Kinase; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms

2022

Trials

2 trials available for temozolomide and Lymphoma, Non-Hodgkin

ArticleYear
Successful change of treatment strategy in elderly patients with primary central nervous system lymphoma by de-escalating induction and introducing temozolomide maintenance: results from a phase II study by the Nordic Lymphoma Group.
    Haematologica, 2015, Volume: 100, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Central Nervous Syst

2015
Phase II trial of temozolomide in low-grade non-Hodgkin's lymphoma.
    British journal of cancer, 1995, Volume: 72, Issue:1

    Topics: Adult; Aged; Antineoplastic Agents; Dacarbazine; Female; Humans; Lymphoma, Non-Hodgkin; Male; Middle

1995

Other Studies

13 other studies available for temozolomide and Lymphoma, Non-Hodgkin

ArticleYear
Primary central nervous system lymphoma: Retrospective analysis of 34 cases in a single centre.
    The Journal of international medical research, 2018, Volume: 46, Issue:2

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Central Nervous System Neoplasms; Child

2018
Stereotactic Brachytherapy with Iodine-125 Seeds Plus Temozolomide Induced Complete and Durable Remission in a Patient with Recurrent Primary Central Nervous System Lymphoma.
    World neurosurgery, 2018, Volume: 117

    Topics: Antineoplastic Agents, Alkylating; Brachytherapy; Central Nervous System Neoplasms; Combined Modalit

2018
miR-370 Sensitizes TMZ Response Dependent of MGMT Status in Primary Central Nervous System Lymphoma.
    Pathology oncology research : POR, 2020, Volume: 26, Issue:2

    Topics: Antineoplastic Agents, Alkylating; Central Nervous System Neoplasms; DNA Modification Methylases; DN

2020
High-dose Methotrexate plus temozolomide with or without rituximab in patients with untreated primary central nervous system lymphoma: A retrospective study from China.
    Cancer medicine, 2019, Volume: 8, Issue:4

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Central Nervous System Neoplasms; Femal

2019
Temozolomide-induced aplastic anaemia and incidental low-grade B-cell non-Hodgkin lymphoma in a geriatric patient with glioblastoma multiforme.
    BMJ case reports, 2019, Jun-29, Volume: 12, Issue:6

    Topics: Aged, 80 and over; Anemia, Aplastic; Antineoplastic Agents, Alkylating; Brain; Brain Neoplasms; Fata

2019
Temozolomide as a Single Agent Maintenance Therapy in Elderly Patients With Primary CNS Lymphoma.
    Clinical lymphoma, myeloma & leukemia, 2019, Volume: 19, Issue:10

    Topics: Aged; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Brain Disea

2019
Secondary non-Hodgkin lymphoma of the ethmoid sinus after temozolomide.
    B-ENT, 2015, Volume: 11, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Dacarbazine; Ethmoid Sinus; Humans; Lymphoma, Non-Hodgkin; Male;

2015
Non-Hodgkin's lymphoma in patients with glioma treated with temozolomide.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2008, Sep-20, Volume: 26, Issue:27

    Topics: Animals; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Dacarbaz

2008
Non-Hodgkin lymphoma following temozolomide.
    Pediatric blood & cancer, 2009, Volume: 53, Issue:4

    Topics: Adult; Antineoplastic Agents, Alkylating; Dacarbazine; Female; Glioblastoma; Humans; Lymphoma, Non-H

2009
Non-Hodgkin's lymphoma in a patient on treatment with temozolomide.
    Asia-Pacific journal of clinical oncology, 2012, Volume: 8, Issue:4

    Topics: Aged; Antineoplastic Agents, Alkylating; Cerebellar Neoplasms; Chemoradiotherapy; Dacarbazine; Gliob

2012
Temozolomide for relapsed primary CNS lymphoma.
    Journal of the College of Physicians and Surgeons--Pakistan : JCPSP, 2012, Volume: 22, Issue:9

    Topics: Adult; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Central Ne

2012
Relapse of primary CNS lymphoma after more than 10 years in complete remission.
    Journal of neurology, 2005, Volume: 252, Issue:11

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Central Nervous System Neoplasms; Combined Mo

2005
Salvage therapy with temozolomide in an immunocompetent patient with primary brain lymphoma.
    Journal of the National Cancer Institute, 2000, Apr-05, Volume: 92, Issue:7

    Topics: Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Humans; Immunocompetence; Lym

2000