temozolomide has been researched along with Lymph Node Metastasis in 19 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| "Temozolomide (Temodar) has demonstrated clinical activity against melanoma equivalent to that of intravenous dacarbazine (DTIC)." | 9.10 | Phase II evaluation of temozolomide in metastatic choroidal melanoma. ( Bedikian, AY; Eton, O; Papadopoulos, N; Plager, C; Ring, S, 2003) |
| " In a clinical trial of temozolomide in advanced malignant melanoma, the relationship between pretreatment MGMT levels in biopsies of cutaneous tumours and involved lymph nodes and clinical response to the drug has been studied." | 9.08 | O6-methylguanine-DNA methyltransferase in pretreatment tumour biopsies as a predictor of response to temozolomide in melanoma. ( Bleehen, NM; Brampton, MH; Calvert, AH; Lee, SM; Lind, MJ; Lunn, JM; Margison, GP; Middleton, MR; Morris, C; Newell, DR; Newlands, ES; Rustin, G; Thatcher, N; Wedge, SR, 1998) |
| "The authors retrospectively evaluated 3 patients with progressive, metastatic neuroendocrine tumors of the thymus who were treated with a combination of capecitabine and temozolomide." | 7.79 | Treatment of metastatic neuroendocrine tumors of the thymus with capecitabine and temozolomide: a case series. ( Centeno, B; Kvols, L; Morse, B; Saranga-Perry, V; Strosberg, J, 2013) |
| " A 67-year-old renal transplant recipient developed a nodular malignant melanoma after 30 years of immunosuppression with azathioprine and prednisolone." | 7.75 | Nodular malignant melanoma and multiple cutaneous neoplasms under immunosuppression with azathioprine. ( Guenova, E; Hoetzenecker, W; Lichte, V; Moehrle, M; Roecken, M; Schaller, M; Woelbing, F, 2009) |
| " 11 (44%) patients showed cerebral metastases prior to therapy with temozolomide." | 7.71 | [Temozolomide as therapeutic option for patients with metastatic melanoma and poor prognosis]. ( Christophers, E; Frick, S; Haacke, TC; Hauschild, A; Lischner, S; Rosien, F; Schäfer, F, 2002) |
| "Temozolomide is a rapidly absorbed chemotherapeutic agent, achieving significant central nervous system penetration." | 6.72 | Alternating chemo-immunotherapy with temozolomide and low-dose interleukin-2 in patients with metastatic melanoma. ( Hansson, J; Månsson-Brahme, E; Masucci, GV; Nilsson, B; Ragnarsson-Olding, B; Wagenius, G, 2006) |
| "Temozolomide (Temodar) has demonstrated clinical activity against melanoma equivalent to that of intravenous dacarbazine (DTIC)." | 5.10 | Phase II evaluation of temozolomide in metastatic choroidal melanoma. ( Bedikian, AY; Eton, O; Papadopoulos, N; Plager, C; Ring, S, 2003) |
| " In a clinical trial of temozolomide in advanced malignant melanoma, the relationship between pretreatment MGMT levels in biopsies of cutaneous tumours and involved lymph nodes and clinical response to the drug has been studied." | 5.08 | O6-methylguanine-DNA methyltransferase in pretreatment tumour biopsies as a predictor of response to temozolomide in melanoma. ( Bleehen, NM; Brampton, MH; Calvert, AH; Lee, SM; Lind, MJ; Lunn, JM; Margison, GP; Middleton, MR; Morris, C; Newell, DR; Newlands, ES; Rustin, G; Thatcher, N; Wedge, SR, 1998) |
| "In the present study we collected fresh-frozen pretreatment lymph-node metastasis samples (n=14) from melanoma patients with differential response to dacarbazine (DTIC) or temozolomide (TMZ) chemotherapy, to identify proteins with an impact on treatment response." | 3.80 | Proteomics analysis of melanoma metastases: association between S100A13 expression and chemotherapy resistance. ( Azimi, A; Egyházi Brage, S; Frostvik Stolt, M; Hansson, J; Hertzman Johansson, C; Lehtiö, J; Pernemalm, M, 2014) |
| "The authors retrospectively evaluated 3 patients with progressive, metastatic neuroendocrine tumors of the thymus who were treated with a combination of capecitabine and temozolomide." | 3.79 | Treatment of metastatic neuroendocrine tumors of the thymus with capecitabine and temozolomide: a case series. ( Centeno, B; Kvols, L; Morse, B; Saranga-Perry, V; Strosberg, J, 2013) |
| " A 67-year-old renal transplant recipient developed a nodular malignant melanoma after 30 years of immunosuppression with azathioprine and prednisolone." | 3.75 | Nodular malignant melanoma and multiple cutaneous neoplasms under immunosuppression with azathioprine. ( Guenova, E; Hoetzenecker, W; Lichte, V; Moehrle, M; Roecken, M; Schaller, M; Woelbing, F, 2009) |
| " 11 (44%) patients showed cerebral metastases prior to therapy with temozolomide." | 3.71 | [Temozolomide as therapeutic option for patients with metastatic melanoma and poor prognosis]. ( Christophers, E; Frick, S; Haacke, TC; Hauschild, A; Lischner, S; Rosien, F; Schäfer, F, 2002) |
| "Temozolomide is a rapidly absorbed chemotherapeutic agent, achieving significant central nervous system penetration." | 2.72 | Alternating chemo-immunotherapy with temozolomide and low-dose interleukin-2 in patients with metastatic melanoma. ( Hansson, J; Månsson-Brahme, E; Masucci, GV; Nilsson, B; Ragnarsson-Olding, B; Wagenius, G, 2006) |
| "As long as metastasis is confined to one organ system and is removable, surgery remains the treatment of first choice." | 2.42 | [Therapy of malignant melanoma at the stage of distant metastasis]. ( Eigentler, TK; Garbe, C, 2004) |
| "Primary vaginal melanoma is a rare, highly malignant, and poor prognostic disease." | 1.35 | Primary malignant melanoma of the vagina. ( Baloglu, A; Bezircioglu, I; Cetinkaya, B; Yavuzcan, A, 2009) |
| "Temozolomide (TMZ) is an alkylating cytostaticum." | 1.35 | Temozolomide treatment of a pituitary carcinoma and two pituitary macroadenomas resistant to conventional therapy. ( Andersen, M; Hagen, C; Hansen, S; Schroeder, HD, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (5.26) | 18.2507 |
| 2000's | 9 (47.37) | 29.6817 |
| 2010's | 9 (47.37) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Janco, JM | 1 |
| Markovic, SN | 1 |
| Weaver, AL | 1 |
| Cliby, WA | 1 |
| Blume, C | 1 |
| von Lehe, M | 1 |
| van Landeghem, F | 1 |
| Greschus, S | 1 |
| Boström, J | 1 |
| Sha, SJ | 1 |
| Wu, HP | 1 |
| Lu, K | 1 |
| Chen, HJ | 1 |
| Huang, PH | 1 |
| Huang, SH | 1 |
| Hsu, CT | 1 |
| Lipson, EJ | 1 |
| Bodell, MA | 1 |
| Kraus, ES | 1 |
| Sharfman, WH | 1 |
| Azimi, A | 1 |
| Pernemalm, M | 1 |
| Frostvik Stolt, M | 1 |
| Hansson, J | 2 |
| Lehtiö, J | 1 |
| Egyházi Brage, S | 1 |
| Hertzman Johansson, C | 1 |
| Baloglu, A | 1 |
| Bezircioglu, I | 1 |
| Cetinkaya, B | 1 |
| Yavuzcan, A | 1 |
| Guenova, E | 1 |
| Lichte, V | 1 |
| Hoetzenecker, W | 1 |
| Woelbing, F | 1 |
| Moehrle, M | 1 |
| Roecken, M | 1 |
| Schaller, M | 1 |
| Hagen, C | 2 |
| Schroeder, HD | 1 |
| Hansen, S | 1 |
| Andersen, M | 1 |
| Paulino, AC | 1 |
| Pappo, A | 1 |
| Fateh, S | 1 |
| Schell, TD | 1 |
| Gingrich, R | 1 |
| Neves, RI | 1 |
| Drabick, JJ | 1 |
| Shacham-Shmueli, E | 1 |
| Beny, A | 1 |
| Geva, R | 1 |
| Blachar, A | 1 |
| Figer, A | 1 |
| Aderka, D | 1 |
| Koreen, L | 1 |
| He, SX | 1 |
| Johnson, MW | 1 |
| Hackel, RE | 1 |
| Khan, NW | 1 |
| Heckenlively, JR | 1 |
| Saranga-Perry, V | 1 |
| Morse, B | 1 |
| Centeno, B | 1 |
| Kvols, L | 1 |
| Strosberg, J | 1 |
| Frick, S | 1 |
| Lischner, S | 1 |
| Rosien, F | 1 |
| Haacke, TC | 1 |
| Schäfer, F | 1 |
| Christophers, E | 1 |
| Hauschild, A | 1 |
| Dréno, B | 1 |
| Wallon-Dumont, G | 1 |
| Bedikian, AY | 1 |
| Papadopoulos, N | 1 |
| Plager, C | 1 |
| Eton, O | 1 |
| Ring, S | 1 |
| Garbe, C | 1 |
| Eigentler, TK | 1 |
| Masucci, GV | 1 |
| Månsson-Brahme, E | 1 |
| Ragnarsson-Olding, B | 1 |
| Nilsson, B | 1 |
| Wagenius, G | 1 |
| Middleton, MR | 1 |
| Lunn, JM | 1 |
| Morris, C | 1 |
| Rustin, G | 1 |
| Wedge, SR | 1 |
| Brampton, MH | 1 |
| Lind, MJ | 1 |
| Lee, SM | 1 |
| Newell, DR | 1 |
| Bleehen, NM | 1 |
| Newlands, ES | 1 |
| Calvert, AH | 1 |
| Margison, GP | 1 |
| Thatcher, N | 1 |
3 reviews available for temozolomide and Lymph Node Metastasis
| Article | Year |
|---|---|
Extracranial glioblastoma with synchronous metastases in the lung, pulmonary lymph nodes, vertebrae, cervical muscles and epidural space in a young patient - case report and review of literature.
Topics: Adult; Antineoplastic Agents, Alkylating; Biopsy; Chemoradiotherapy, Adjuvant; Dacarbazine; Epidural | 2013 |
[Treatment of melanoma].
Topics: Antineoplastic Agents; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Proto | 2003 |
[Therapy of malignant melanoma at the stage of distant metastasis].
Topics: Antineoplastic Agents; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Phytogenic; Antineo | 2004 |
3 trials available for temozolomide and Lymph Node Metastasis
| Article | Year |
|---|---|
Phase II evaluation of temozolomide in metastatic choroidal melanoma.
Topics: Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Choroid Neoplasms; Dacarbazine; Female; | 2003 |
Alternating chemo-immunotherapy with temozolomide and low-dose interleukin-2 in patients with metastatic melanoma.
Topics: Administration, Oral; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Dacarbazine; Fema | 2006 |
O6-methylguanine-DNA methyltransferase in pretreatment tumour biopsies as a predictor of response to temozolomide in melanoma.
Topics: Adult; Antineoplastic Agents, Alkylating; Biopsy; Dacarbazine; Female; Humans; Leukocytes, Mononucle | 1998 |
13 other studies available for temozolomide and Lymph Node Metastasis
| Article | Year |
|---|---|
Vulvar and vaginal melanoma: case series and review of current management options including neoadjuvant chemotherapy.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Chemotherapy, Adjuvant; Dacarbazine; Fe | 2013 |
Extraneural metastases of anaplastic oligodendroglioma.
Topics: Antineoplastic Agents, Alkylating; Bone Neoplasms; Brain Neoplasms; Dacarbazine; Humans; Lymphatic M | 2014 |
Successful administration of ipilimumab to two kidney transplantation patients with metastatic melanoma.
Topics: Administration, Oral; Aged; Antibodies, Monoclonal; Antineoplastic Agents; Dacarbazine; Drug Adminis | 2014 |
Proteomics analysis of melanoma metastases: association between S100A13 expression and chemotherapy resistance.
Topics: Adult; Aged; Antineoplastic Agents; Cystatin B; Dacarbazine; Drug Resistance, Neoplasm; Factor XIII; | 2014 |
Primary malignant melanoma of the vagina.
Topics: Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Dacarbazine; Female; Humans; Interferon-a | 2009 |
Nodular malignant melanoma and multiple cutaneous neoplasms under immunosuppression with azathioprine.
Topics: Aged; Antineoplastic Agents, Alkylating; Azathioprine; Carcinoma, Basal Cell; Carcinoma, Squamous Ce | 2009 |
Temozolomide treatment of a pituitary carcinoma and two pituitary macroadenomas resistant to conventional therapy.
Topics: Antineoplastic Agents, Alkylating; Dacarbazine; Drug Resistance, Neoplasm; Female; Hormones; Humans; | 2009 |
Alveolar rhabdomyosarcoma of the extremity and nodal metastasis: Is the in-transit lymphatic system at risk?
Topics: Antineoplastic Combined Chemotherapy Protocols; Benzenesulfonates; Camptothecin; Child; Combined Mod | 2009 |
Unsuccessful high dose IL-2 therapy followed immediately by near continuous low dose temozolomide can result in rapid durable complete and near-complete remissions in metastatic melanoma.
Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Dacarbazine; Disease Progression; Dose-Response Rela | 2010 |
Response to temozolomide in patients with metastatic colorectal cancer with loss of MGMT expression: a new approach in the era of personalized medicine?
Topics: Adenocarcinoma; Aged; Antineoplastic Agents, Alkylating; Biopsy; Colectomy; Colorectal Neoplasms; Da | 2011 |
Anti-retinal pigment epithelium antibodies in acute exudative polymorphous vitelliform maculopathy: a new hypothesis about disease pathogenesis.
Topics: Acute Disease; Antineoplastic Agents, Alkylating; Autoantibodies; Autoantigens; Blotting, Western; C | 2011 |
Treatment of metastatic neuroendocrine tumors of the thymus with capecitabine and temozolomide: a case series.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Dacarbazine; Deoxycytidine; Flu | 2013 |
[Temozolomide as therapeutic option for patients with metastatic melanoma and poor prognosis].
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neopl | 2002 |