temozolomide has been researched along with Intradural-Extramedullary Spinal Cord Neoplasms in 27 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| "Patients age 18 or older with histologically proven and progressive ependymoma or anaplastic ependymoma were eligible and received dose-dense TMZ and daily lapatinib." | 9.41 | A phase II study of dose-dense temozolomide and lapatinib for recurrent low-grade and anaplastic supratentorial, infratentorial, and spinal cord ependymoma. ( Aldape, K; Armstrong, TS; Gerstner, ER; Gilbert, MR; Lieberman, F; Mendoza, T; Mikkelsen, T; Omuro, A; Robins, HI; Vera, E; Wen, PY; Wu, J; Yuan, Y, 2021) |
| "Based on our findings in two paediatric patients, temozolomide may be a useful agent in the management of progressive recurrent low grade spinal cord astrocytomas." | 9.12 | Role of temozolomide in spinal cord low grade astrocytomas: results in two paediatric patients. ( Abboud, MR; Al Kutoubi, AO; Alaraj, AM; Chamoun, RB; Haddad, GF, 2006) |
| "Since virtually no trials have evaluated the effectiveness of temozolomide (TMZ) in the treatment of spinal cord (SC) glioblastoma multiforme (GBM), we conducted a systematic review to evaluate its efficacy." | 8.91 | Primary spinal cord glioblastoma multiforme treated with temozolomide. ( Bregy, A; Hanft, S; Hernández-Durán, S; Komotar, RJ; Manzano, GR; Shah, AH, 2015) |
| "We retrospectively analyzed the data of 5 adult patients treated with temozolomide between 2008 and 2015 for a grade II intramedullary astrocytoma with progression after surgery." | 7.85 | [Contribution of temozolomide chemotherapy for intramedullary grade II spinal cord astrocytomas in adults: Our experience]. ( Chaskis, E; De Witte, O; Devriendt, D; Goldman, S; Lefranc, F; Luce, S; Minichini, V; Sadeghi, N, 2017) |
| "We report a case of prolonged survival in a patient with cervical intramedullary glioblastoma multiforme (GBM) treated with total resection, radiotherapy, and temozolomide." | 7.76 | Prolonged survival of a patient with cervical intramedullary glioblastoma multiforme treated with total resection, radiation therapy, and temozolomide. ( Huang, CY; Kuo, LT; Lien, HC; Liu, KL; Liu, MT; Tseng, HM, 2010) |
| "Myxopapillary ependymomas are intradural tumors which grow from the terminal filum of the spinal cord." | 6.58 | Remarkable efficacy of temozolomide for relapsed spinal myxopapillary ependymoma with multiple recurrence and cerebrospinal dissemination: a case report and literature review. ( Adachi, N; Fujiwara, Y; Izumi, B; Manabe, H; Shima, T, 2018) |
| "Patients age 18 or older with histologically proven and progressive ependymoma or anaplastic ependymoma were eligible and received dose-dense TMZ and daily lapatinib." | 5.41 | A phase II study of dose-dense temozolomide and lapatinib for recurrent low-grade and anaplastic supratentorial, infratentorial, and spinal cord ependymoma. ( Aldape, K; Armstrong, TS; Gerstner, ER; Gilbert, MR; Lieberman, F; Mendoza, T; Mikkelsen, T; Omuro, A; Robins, HI; Vera, E; Wen, PY; Wu, J; Yuan, Y, 2021) |
| "Temozolomide was administered to three patients at initial diagnosis and five patients at recurrence after failing prior radiotherapy." | 5.38 | Temozolomide or bevacizumab for spinal cord high-grade gliomas. ( Gavrilovic, IT; Kaley, TJ; Mondesire-Crump, I, 2012) |
| "Histology revealed an anaplastic oligodendroglioma." | 5.37 | Spinal cord anaplastic oligodendroglioma with 1p deletion: report of a relapsing case treated with temozolomide. ( Lou, X; Qiao, G; Wang, F, 2011) |
| "Treatment with temozolomide resulted in relief of clinical symptoms and stabilization of tumour growth for 8 months." | 5.34 | Metastatic medulloblastoma in an adult; treatment with temozolomide. ( Bernsen, HJ; Poelen, J; Prick, MJ, 2007) |
| "Based on our findings in two paediatric patients, temozolomide may be a useful agent in the management of progressive recurrent low grade spinal cord astrocytomas." | 5.12 | Role of temozolomide in spinal cord low grade astrocytomas: results in two paediatric patients. ( Abboud, MR; Al Kutoubi, AO; Alaraj, AM; Chamoun, RB; Haddad, GF, 2006) |
| "Since virtually no trials have evaluated the effectiveness of temozolomide (TMZ) in the treatment of spinal cord (SC) glioblastoma multiforme (GBM), we conducted a systematic review to evaluate its efficacy." | 4.91 | Primary spinal cord glioblastoma multiforme treated with temozolomide. ( Bregy, A; Hanft, S; Hernández-Durán, S; Komotar, RJ; Manzano, GR; Shah, AH, 2015) |
| "We retrospectively analyzed the data of 5 adult patients treated with temozolomide between 2008 and 2015 for a grade II intramedullary astrocytoma with progression after surgery." | 3.85 | [Contribution of temozolomide chemotherapy for intramedullary grade II spinal cord astrocytomas in adults: Our experience]. ( Chaskis, E; De Witte, O; Devriendt, D; Goldman, S; Lefranc, F; Luce, S; Minichini, V; Sadeghi, N, 2017) |
| "We report a case of prolonged survival in a patient with cervical intramedullary glioblastoma multiforme (GBM) treated with total resection, radiotherapy, and temozolomide." | 3.76 | Prolonged survival of a patient with cervical intramedullary glioblastoma multiforme treated with total resection, radiation therapy, and temozolomide. ( Huang, CY; Kuo, LT; Lien, HC; Liu, KL; Liu, MT; Tseng, HM, 2010) |
| " There was no clear relationship between vorinostat dosage and drug exposure over the dose range studied." | 2.78 | A pediatric phase 1 trial of vorinostat and temozolomide in relapsed or refractory primary brain or spinal cord tumors: a Children's Oncology Group phase 1 consortium study. ( Ahern, C; Ames, MM; Blaney, SM; Fouladi, M; Gilbertson, RJ; Horton, T; Hummel, TR; Ingle, AM; McGovern, RM; Reid, JM; Wagner, L; Weigel, B, 2013) |
| "Myxopapillary ependymomas are intradural tumors which grow from the terminal filum of the spinal cord." | 2.58 | Remarkable efficacy of temozolomide for relapsed spinal myxopapillary ependymoma with multiple recurrence and cerebrospinal dissemination: a case report and literature review. ( Adachi, N; Fujiwara, Y; Izumi, B; Manabe, H; Shima, T, 2018) |
| "Glioblastoma multiforme is one of the most common malignant types of tumor arising from the central nervous system known for its devastating intracranial progress and dismal prognosis." | 1.62 | FDG PET/CT in Recurrent Glioblastoma Multiforme With Leptomeningeal and Diffuse Spinal Cord Metastasis. ( Malik, D, 2021) |
| "Spinal cord oligodendrogliomas are rare tumors, with a reported incidence varying between 0." | 1.43 | Spinal Anaplastic Oligodendroglioma With Oligodendrogliomatosis: Molecular Markers and Management: Case Report. ( Cachia, D; Cykowski, MD; Jalali, A; Langford, LA; Li, J; Penas-Prado, M; Shah, K; Strickland, BA; Weinberg, JS, 2016) |
| "Temozolomide was administered to three patients at initial diagnosis and five patients at recurrence after failing prior radiotherapy." | 1.38 | Temozolomide or bevacizumab for spinal cord high-grade gliomas. ( Gavrilovic, IT; Kaley, TJ; Mondesire-Crump, I, 2012) |
| "Histological examination revealed anaplastic astrocytoma." | 1.38 | Radiation-induced spinal cord anaplastic astrocytoma subsequent to radiotherapy for testicular seminoma. ( Hoshimaru, M; Kawanabe, Y; Kihara, S; Koizumi, T; Sasaki, N; Sawada, M; Ueda, S; Yukawa, H, 2012) |
| "Histology revealed an anaplastic oligodendroglioma." | 1.37 | Spinal cord anaplastic oligodendroglioma with 1p deletion: report of a relapsing case treated with temozolomide. ( Lou, X; Qiao, G; Wang, F, 2011) |
| "Intramedullary gangliogliomas are indolent tumors of the spine with rare cases of malignant transformation." | 1.34 | Malignant transformation of conus medullaris ganglioglioma: case report. ( Amini, A; Chin, SS; Schmidt, MH, 2007) |
| "Temozolomide was administered at a dose of 200 mg/m(2) daily for 5 days, in a 4-week cycle." | 1.34 | Temozolomide in pediatric low-grade glioma. ( Ashley, DM; Coleman, LT; Downie, PA; Heath, JA; Khaw, SL, 2007) |
| "Treatment with temozolomide resulted in relief of clinical symptoms and stabilization of tumour growth for 8 months." | 1.34 | Metastatic medulloblastoma in an adult; treatment with temozolomide. ( Bernsen, HJ; Poelen, J; Prick, MJ, 2007) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 8 (29.63) | 29.6817 |
| 2010's | 16 (59.26) | 24.3611 |
| 2020's | 3 (11.11) | 2.80 |
| Authors | Studies |
|---|---|
| Yang, K | 1 |
| Man, W | 1 |
| Jing, L | 1 |
| Sun, Z | 1 |
| Liang, P | 1 |
| Wang, J | 1 |
| Wang, G | 1 |
| Gilbert, MR | 1 |
| Yuan, Y | 1 |
| Wu, J | 2 |
| Mendoza, T | 1 |
| Vera, E | 1 |
| Omuro, A | 1 |
| Lieberman, F | 1 |
| Robins, HI | 1 |
| Gerstner, ER | 1 |
| Wen, PY | 1 |
| Mikkelsen, T | 1 |
| Aldape, K | 1 |
| Armstrong, TS | 1 |
| Malik, D | 1 |
| Cheng, X | 1 |
| Lou, S | 1 |
| Huang, S | 1 |
| Chen, H | 1 |
| Liu, J | 1 |
| Takai, K | 1 |
| Tanaka, S | 1 |
| Sota, T | 1 |
| Mukasa, A | 1 |
| Komori, T | 1 |
| Taniguchi, M | 1 |
| Chaskis, E | 1 |
| Minichini, V | 1 |
| Luce, S | 1 |
| Devriendt, D | 1 |
| Goldman, S | 1 |
| De Witte, O | 1 |
| Sadeghi, N | 1 |
| Lefranc, F | 1 |
| van der Vlist, A | 1 |
| Snijders, TJ | 1 |
| Stades, AME | 1 |
| Spliet, WGM | 1 |
| De Vos, FYFL | 1 |
| Fujiwara, Y | 1 |
| Manabe, H | 1 |
| Izumi, B | 1 |
| Shima, T | 1 |
| Adachi, N | 1 |
| Grah, JJ | 1 |
| Katalinic, D | 1 |
| Stern-Padovan, R | 1 |
| Paladino, J | 1 |
| Santek, F | 1 |
| Juretic, A | 1 |
| Zarkovic, K | 1 |
| Plestina, S | 1 |
| Supe, M | 1 |
| Hummel, TR | 1 |
| Wagner, L | 1 |
| Ahern, C | 1 |
| Fouladi, M | 1 |
| Reid, JM | 1 |
| McGovern, RM | 1 |
| Ames, MM | 1 |
| Gilbertson, RJ | 1 |
| Horton, T | 1 |
| Ingle, AM | 1 |
| Weigel, B | 1 |
| Blaney, SM | 1 |
| Gwak, SJ | 1 |
| An, SS | 1 |
| Yang, MS | 1 |
| Joe, E | 1 |
| Kim, DH | 1 |
| Yoon, DH | 1 |
| Kim, KN | 1 |
| Ha, Y | 1 |
| Lau, PK | 1 |
| Lee, G | 1 |
| Bynevelt, M | 1 |
| Nowak, AK | 1 |
| Strickland, BA | 1 |
| Cachia, D | 1 |
| Jalali, A | 1 |
| Cykowski, MD | 1 |
| Penas-Prado, M | 1 |
| Langford, LA | 1 |
| Li, J | 1 |
| Shah, K | 1 |
| Weinberg, JS | 1 |
| Hernández-Durán, S | 1 |
| Bregy, A | 1 |
| Shah, AH | 1 |
| Hanft, S | 1 |
| Komotar, RJ | 1 |
| Manzano, GR | 1 |
| Chamberlain, MC | 1 |
| Kim, WH | 2 |
| Yoon, SH | 1 |
| Kim, CY | 1 |
| Kim, KJ | 1 |
| Lee, MM | 1 |
| Choe, G | 1 |
| Kim, IA | 1 |
| Kim, JH | 1 |
| Kim, YJ | 1 |
| Kim, HJ | 1 |
| Tseng, HM | 1 |
| Kuo, LT | 1 |
| Lien, HC | 1 |
| Liu, KL | 1 |
| Liu, MT | 1 |
| Huang, CY | 1 |
| Wang, F | 1 |
| Qiao, G | 1 |
| Lou, X | 1 |
| Kaley, TJ | 1 |
| Mondesire-Crump, I | 1 |
| Gavrilovic, IT | 1 |
| Kawanabe, Y | 1 |
| Sawada, M | 1 |
| Yukawa, H | 1 |
| Ueda, S | 1 |
| Sasaki, N | 1 |
| Koizumi, T | 1 |
| Kihara, S | 1 |
| Hoshimaru, M | 1 |
| Salmaggi, A | 1 |
| Silvani, A | 1 |
| Eoli, M | 1 |
| Lamperti, E | 1 |
| Boiardi, A | 1 |
| Chamoun, RB | 1 |
| Alaraj, AM | 1 |
| Al Kutoubi, AO | 1 |
| Abboud, MR | 1 |
| Haddad, GF | 1 |
| Amini, A | 1 |
| Chin, SS | 1 |
| Schmidt, MH | 1 |
| Rovin, RA | 1 |
| Winn, R | 1 |
| Khaw, SL | 1 |
| Coleman, LT | 1 |
| Downie, PA | 1 |
| Heath, JA | 1 |
| Ashley, DM | 1 |
| Poelen, J | 1 |
| Bernsen, HJ | 1 |
| Prick, MJ | 1 |
| Groves, MD | 1 |
| Katz, RL | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Phase I Study of SAHA and Temozolomide in Children With Relapsed or Refractory Primary Brain or Spinal Cord Tumors[NCT01076530] | Phase 1 | 27 participants (Actual) | Interventional | 2010-02-28 | Completed | ||
| Genomic Landscape of Intramedullary Astrocytoma[NCT04211974] | 50 participants (Anticipated) | Observational | 2019-12-10 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
4 reviews available for temozolomide and Intradural-Extramedullary Spinal Cord Neoplasms
| Article | Year |
|---|---|
Clinical Features and Outcomes of Primary Spinal Cord Glioblastoma: A Single-Center Experience and Literature Review.
Topics: Adolescent; Adult; Age Factors; Aged; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Immu | 2020 |
Remarkable efficacy of temozolomide for relapsed spinal myxopapillary ependymoma with multiple recurrence and cerebrospinal dissemination: a case report and literature review.
Topics: Adult; Antineoplastic Agents, Alkylating; Cauda Equina; Chemotherapy, Adjuvant; Combined Modality Th | 2018 |
Primary spinal cord glioblastoma multiforme treated with temozolomide.
Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Dacarbazine; Female; Glioblastoma; Humans; Kaplan-Me | 2015 |
Temozolomide for malignant primary spinal cord glioma: an experience of six cases and a literature review.
Topics: Adolescent; Antineoplastic Agents, Alkylating; Combined Modality Therapy; Dacarbazine; Female; Gliom | 2011 |
4 trials available for temozolomide and Intradural-Extramedullary Spinal Cord Neoplasms
| Article | Year |
|---|---|
A phase II study of dose-dense temozolomide and lapatinib for recurrent low-grade and anaplastic supratentorial, infratentorial, and spinal cord ependymoma.
Topics: Adolescent; Adult; Brain Neoplasms; Dacarbazine; Disease-Free Survival; Ependymoma; Humans; Lapatini | 2021 |
A pediatric phase 1 trial of vorinostat and temozolomide in relapsed or refractory primary brain or spinal cord tumors: a Children's Oncology Group phase 1 consortium study.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Child; Child, Pr | 2013 |
Temozolomide and cisplatin in the treatment of leptomeningeal metastatic involvement from melanoma: a case report.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Dacarbazine; Humans; Magnetic Reso | 2002 |
Role of temozolomide in spinal cord low grade astrocytomas: results in two paediatric patients.
Topics: Adolescent; Antineoplastic Agents, Alkylating; Astrocytoma; Child; Dacarbazine; Disease Progression; | 2006 |
19 other studies available for temozolomide and Intradural-Extramedullary Spinal Cord Neoplasms
| Article | Year |
|---|---|
FDG PET/CT in Recurrent Glioblastoma Multiforme With Leptomeningeal and Diffuse Spinal Cord Metastasis.
Topics: Adult; Brain Neoplasms; Female; Fluorodeoxyglucose F18; Glioblastoma; Humans; Meningeal Neoplasms; P | 2021 |
Primary Spinal Cord Glioblastoma Multiforme: A Retrospective Study of Patients at a Single Institution.
Topics: Adolescent; Adult; Antineoplastic Agents, Alkylating; Combined Modality Therapy; Dacarbazine; Female | 2017 |
Spinal Cord Astrocytoma with Isocitrate Dehydrogenase 1 Gene Mutation.
Topics: Adult; Antineoplastic Agents, Alkylating; Astrocytoma; Chemoradiotherapy, Adjuvant; Dacarbazine; Fat | 2017 |
[Contribution of temozolomide chemotherapy for intramedullary grade II spinal cord astrocytomas in adults: Our experience].
Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Astrocytoma; Chemotherapy, Adjuvant; Dacarbazine; Di | 2017 |
Successful treatment of leptomeningeally metastasised pituitary carcinoma with temozolomide.
Topics: Aged; Antineoplastic Agents, Alkylating; Dacarbazine; Humans; Male; Meningeal Neoplasms; Pituitary N | 2017 |
Leptomeningeal and intramedullary metastases of glioblastoma multiforme in a patient reoperated during adjuvant radiochemotherapy.
Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy, Adjuvant; Combined Modality T | 2013 |
Effect of combined bevacizumab and temozolomide treatment on intramedullary spinal cord tumor.
Topics: Animals; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Bevacizu | 2014 |
Marked functional improvement after combined chemoradiotherapy for cervical spine glioblastoma causing quadriparesis in an adolescent.
Topics: Adolescent; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Antineoplastic Agents, Alkyl | 2014 |
Spinal Anaplastic Oligodendroglioma With Oligodendrogliomatosis: Molecular Markers and Management: Case Report.
Topics: Aged; Antineoplastic Agents, Alkylating; Chemoradiotherapy; Dacarbazine; Humans; Magnetic Resonance | 2016 |
Temozolomide for recurrent low-grade spinal cord gliomas in adults.
Topics: Adult; Antineoplastic Agents, Alkylating; Dacarbazine; Disease-Free Survival; Drug Administration Sc | 2008 |
Prolonged survival of a patient with cervical intramedullary glioblastoma multiforme treated with total resection, radiation therapy, and temozolomide.
Topics: Adult; Antineoplastic Agents, Alkylating; Biopsy; Cervical Vertebrae; Chemotherapy, Adjuvant; Combin | 2010 |
Spinal cord anaplastic oligodendroglioma with 1p deletion: report of a relapsing case treated with temozolomide.
Topics: Adolescent; Antineoplastic Agents, Alkylating; Chromosome Deletion; Chromosomes, Human, Pair 1; Daca | 2011 |
Temozolomide or bevacizumab for spinal cord high-grade gliomas.
Topics: Adult; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Antineoplastic Agents, Alkylating | 2012 |
Radiation-induced spinal cord anaplastic astrocytoma subsequent to radiotherapy for testicular seminoma.
Topics: Antineoplastic Agents; Astrocytoma; Chemotherapy, Adjuvant; Combined Modality Therapy; Dacarbazine; | 2012 |
Malignant transformation of conus medullaris ganglioglioma: case report.
Topics: Adult; Antineoplastic Agents; Combined Modality Therapy; Dacarbazine; Ganglioglioma; Glioblastoma; H | 2007 |
Expression of O6-methylguanine-deoxyribose nucleic acid methyltransferase and temozolomide response in a patient with a malignant spinal cord astrocytoma. Case report.
Topics: Adult; Antineoplastic Agents, Alkylating; Astrocytoma; Combined Modality Therapy; Dacarbazine; Femal | 2007 |
Temozolomide in pediatric low-grade glioma.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Astrocytoma; Brain Neoplasms; Carboplati | 2007 |
Metastatic medulloblastoma in an adult; treatment with temozolomide.
Topics: Adult; Antineoplastic Agents, Alkylating; Cerebellar Neoplasms; Dacarbazine; Female; Humans; Magneti | 2007 |
Low grade astrocytoma presenting with visual loss.
Topics: Adolescent; Antineoplastic Agents, Alkylating; Astrocytoma; Biomarkers, Tumor; Brain Neoplasms; Daca | 2008 |