Page last updated: 2024-11-04

temozolomide and Experimental Leukemia

temozolomide has been researched along with Experimental Leukemia in 2 studies

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19901 (50.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Stevens, MF1
Hickman, JA1
Stone, R1
Gibson, NW1
Baig, GU1
Lunt, E1
Newton, CG1
Braun, CJ1
Bruno, PM1
Horlbeck, MA1
Gilbert, LA1
Weissman, JS1
Hemann, MT1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Phase II Study of Gamma Knife Radiosurgery and Temozolomide (Temodar) for Newly Diagnosed Brain Metastases[NCT00582075]Phase 225 participants (Actual)Interventional2002-07-31Completed
A Pilot Study Investigating Neoadjuvant Temozolomide-based Proton Chemoradiotherapy for High-Risk Soft Tissue Sarcomas[NCT00881595]Phase 20 participants (Actual)Interventional2009-02-28Withdrawn (stopped due to No patients accrued since study opened)
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Overall Survival

(NCT00582075)
Timeframe: 2 years

Interventionweeks (Median)
Radiosurgery 15-24 Gy + Adjuvant Temozolomide31

Percentage of Participants With Distant Brain Failure (DBF) at One Year

Patients developing distant brain failure (DBF) at one year. An approximation method was used to arrive at the reported percentage. (NCT00582075)
Timeframe: 1 years

Interventionpercentage of participants (Number)
Radiosurgery 15-24 Gy + Adjuvant Temozolomide37

Other Studies

2 other studies available for temozolomide and Experimental Leukemia

ArticleYear
Antitumor imidazotetrazines. 1. Synthesis and chemistry of 8-carbamoyl-3-(2-chloroethyl)imidazo[5,1-d]-1,2,3,5-tetrazin-4(3 H)-one , a novel broad-spectrum antitumor agent.
    Journal of medicinal chemistry, 1984, Volume: 27, Issue:2

    Topics: Animals; Antineoplastic Agents; Chemical Phenomena; Chemistry; Imidazoles; Leukemia, Experimental; M

1984
Antitumor imidazotetrazines. 1. Synthesis and chemistry of 8-carbamoyl-3-(2-chloroethyl)imidazo[5,1-d]-1,2,3,5-tetrazin-4(3 H)-one , a novel broad-spectrum antitumor agent.
    Journal of medicinal chemistry, 1984, Volume: 27, Issue:2

    Topics: Animals; Antineoplastic Agents; Chemical Phenomena; Chemistry; Imidazoles; Leukemia, Experimental; M

1984
Antitumor imidazotetrazines. 1. Synthesis and chemistry of 8-carbamoyl-3-(2-chloroethyl)imidazo[5,1-d]-1,2,3,5-tetrazin-4(3 H)-one , a novel broad-spectrum antitumor agent.
    Journal of medicinal chemistry, 1984, Volume: 27, Issue:2

    Topics: Animals; Antineoplastic Agents; Chemical Phenomena; Chemistry; Imidazoles; Leukemia, Experimental; M

1984
Antitumor imidazotetrazines. 1. Synthesis and chemistry of 8-carbamoyl-3-(2-chloroethyl)imidazo[5,1-d]-1,2,3,5-tetrazin-4(3 H)-one , a novel broad-spectrum antitumor agent.
    Journal of medicinal chemistry, 1984, Volume: 27, Issue:2

    Topics: Animals; Antineoplastic Agents; Chemical Phenomena; Chemistry; Imidazoles; Leukemia, Experimental; M

1984
Versatile in vivo regulation of tumor phenotypes by dCas9-mediated transcriptional perturbation.
    Proceedings of the National Academy of Sciences of the United States of America, 2016, 07-05, Volume: 113, Issue:27

    Topics: Animals; Bacterial Proteins; CRISPR-Associated Protein 9; Dacarbazine; DNA Damage; DNA Modification

2016