temozolomide has been researched along with Cushing Syndrome in 2 studies
Cushing Syndrome: A condition caused by prolonged exposure to excess levels of cortisol (HYDROCORTISONE) or other GLUCOCORTICOIDS from endogenous or exogenous sources. It is characterized by upper body OBESITY; OSTEOPOROSIS; HYPERTENSION; DIABETES MELLITUS; HIRSUTISM; AMENORRHEA; and excess body fluid. Endogenous Cushing syndrome or spontaneous hypercortisolism is divided into two groups, those due to an excess of ADRENOCORTICOTROPIN and those that are ACTH-independent.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Targeting dopamine and somatostatin receptors on corticotroph adenomas with cabergoline or pasireotide, or both, controls cortisol production in up to 40% of patients." | 5.01 | Advances in the medical treatment of Cushing's syndrome. ( Feelders, RA; Hofland, LJ; Lacroix, A; Newell-Price, J; Nieman, LK; Pivonello, R, 2019) |
| "Three cases of patients with pituitary adenomas who underwent temozolomide treatment are presented." | 3.75 | Use of temozolomide in aggressive pituitary tumors: case report. ( Cusimano, MD; Kovacs, K; Mason, W; Mohammed, S; Smyth, H, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Feelders, RA | 1 |
| Newell-Price, J | 1 |
| Pivonello, R | 1 |
| Nieman, LK | 1 |
| Hofland, LJ | 1 |
| Lacroix, A | 1 |
| Mohammed, S | 1 |
| Kovacs, K | 1 |
| Mason, W | 1 |
| Smyth, H | 1 |
| Cusimano, MD | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Metabolic, Pressor and Neuropsychological Effects of Metyrapone Treatment in Patients With Hypercortisolism[NCT05255900] | 20 participants (Anticipated) | Observational | 2022-04-28 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for temozolomide and Cushing Syndrome
| Article | Year |
|---|---|
Advances in the medical treatment of Cushing's syndrome.
Topics: ACTH Syndrome, Ectopic; ACTH-Secreting Pituitary Adenoma; Adenoma; Adrenal Gland Neoplasms; Antibodi | 2019 |
1 other study available for temozolomide and Cushing Syndrome
| Article | Year |
|---|---|
Use of temozolomide in aggressive pituitary tumors: case report.
Topics: Adenoma; Adult; Antineoplastic Agents, Alkylating; Cushing Syndrome; Dacarbazine; Female; Humans; Ma | 2009 |