temozolomide has been researched along with Colonic Inertia in 3 studies
Colonic Inertia: Symptom characterized by the passage of stool once a week or less.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Cabozantinib inhibits mesenchymal-epithelial transition factor (MET) and vascular endothelial growth factor receptor 2 (VEGFR2) and has demonstrated activity in patients with recurrent glioblastoma, warranting evaluation of the addition of cabozantinib to radiotherapy (RT) and temozolomide (TMZ) for patients with newly diagnosed high-grade glioma." | 5.22 | Phase 1 dose escalation trial of the safety and pharmacokinetics of cabozantinib concurrent with temozolomide and radiotherapy or temozolomide after radiotherapy in newly diagnosed patients with high-grade gliomas. ( Chamberlain, MC; Cloughesy, T; Desjardins, A; Glantz, M; Mikkelsen, T; Reardon, DA; Schiff, D; Wen, PY, 2016) |
| "Ratio of log-transformed means (intravenous:oral) of area under the concentration-time curve and maximum concentration of drug after dosing for temozolomide and 5-(3-methyltriazen-1-yl)imidazole-4-carboxamide (MTIC) met exposure equivalence criteria (90% confidence interval = 0." | 2.75 | Evaluation of the exposure equivalence of oral versus intravenous temozolomide. ( Abutarif, MA; Cantillon, M; Cutler, D; Diez, BD; Kantesaria, B; Ottaviano, FH; Pallotta, MG; Schwarz, M; Statkevich, P; Xuan, F; Zhu, Y, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 2 (66.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Schiff, D | 1 |
| Desjardins, A | 1 |
| Cloughesy, T | 1 |
| Mikkelsen, T | 1 |
| Glantz, M | 1 |
| Chamberlain, MC | 1 |
| Reardon, DA | 1 |
| Wen, PY | 1 |
| Diez, BD | 1 |
| Statkevich, P | 1 |
| Zhu, Y | 1 |
| Abutarif, MA | 1 |
| Xuan, F | 1 |
| Kantesaria, B | 1 |
| Cutler, D | 1 |
| Cantillon, M | 1 |
| Schwarz, M | 1 |
| Pallotta, MG | 1 |
| Ottaviano, FH | 1 |
| Brandes, AA | 1 |
| Tosoni, A | 1 |
| Cavallo, G | 1 |
| Bertorelle, R | 1 |
| Gioia, V | 1 |
| Franceschi, E | 1 |
| Biscuola, M | 1 |
| Blatt, V | 1 |
| Crinò, L | 1 |
| Ermani, M | 1 |
3 trials available for temozolomide and Colonic Inertia
| Article | Year |
|---|---|
Phase 1 dose escalation trial of the safety and pharmacokinetics of cabozantinib concurrent with temozolomide and radiotherapy or temozolomide after radiotherapy in newly diagnosed patients with high-grade gliomas.
Topics: Adult; Aged; Alanine Transaminase; Anilides; Antineoplastic Combined Chemotherapy Protocols; Asparta | 2016 |
Evaluation of the exposure equivalence of oral versus intravenous temozolomide.
Topics: Administration, Oral; Adult; Anemia; Antineoplastic Agents, Alkylating; Area Under Curve; Central Ne | 2010 |
Temozolomide 3 weeks on and 1 week off as first-line therapy for recurrent glioblastoma: phase II study from gruppo italiano cooperativo di neuro-oncologia (GICNO).
Topics: Adult; Aged; Anemia; Antineoplastic Agents, Alkylating; Brain Neoplasms; Constipation; Dacarbazine; | 2006 |