Page last updated: 2024-11-04

temozolomide and Chromosomal Instability

temozolomide has been researched along with Chromosomal Instability in 2 studies

Chromosomal Instability: An increased tendency to acquire CHROMOSOME ABERRATIONS when various processes involved in chromosome replication, repair, or segregation are dysfunctional.

Research Excerpts

ExcerptRelevanceReference
"Temozolomide treatment of 293_pcDNA3."1.42Step-wise and punctuated genome evolution drive phenotype changes of tumor cells. ( Andreieva, S; Huleyuk, N; Kavsan, V; Korets, K; Mykytenko, D; Stepanenko, A; Vassetzky, Y, 2015)
"Glioblastoma multiforme is characterised by invasive growth and frequent recurrence."1.34Dynamics of chemosensitivity and chromosomal instability in recurrent glioblastoma. ( Berger, W; Buchroithner, J; Fischer, J; Marosi, C; Micksche, M; Pichler, J; Pirker, C; Silye, R; Spiegl-Kreinecker, S, 2007)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (50.00)29.6817
2010's1 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Stepanenko, A1
Andreieva, S1
Korets, K1
Mykytenko, D1
Huleyuk, N1
Vassetzky, Y1
Kavsan, V1
Spiegl-Kreinecker, S1
Pirker, C1
Marosi, C1
Buchroithner, J1
Pichler, J1
Silye, R1
Fischer, J1
Micksche, M1
Berger, W1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Multicenter Phase II Study of Preoperative Chemoradiotherapy With CApecitabine Plus Temozolomide in Patients With MGMT Silenced and Microsatellite Stable Locally Advanced RecTal Cancer: the CATARTIC Trial[NCT05136326]Phase 221 participants (Anticipated)Interventional2021-12-01Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Other Studies

2 other studies available for temozolomide and Chromosomal Instability

ArticleYear
Step-wise and punctuated genome evolution drive phenotype changes of tumor cells.
    Mutation research, 2015, Volume: 771

    Topics: Antineoplastic Agents, Alkylating; Chromosomal Instability; Dacarbazine; DNA Damage; Evolution, Mole

2015
Dynamics of chemosensitivity and chromosomal instability in recurrent glioblastoma.
    British journal of cancer, 2007, Mar-26, Volume: 96, Issue:6

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Chromosomal Instability; Dacar

2007