temozolomide has been researched along with Cholestasis in 5 studies
Cholestasis: Impairment of bile flow due to obstruction in small bile ducts (INTRAHEPATIC CHOLESTASIS) or obstruction in large bile ducts (EXTRAHEPATIC CHOLESTASIS).
| Excerpt | Relevance | Reference |
|---|---|---|
| "Glioblastoma patients undergoing treatment with surgery followed by radiation and temozolomide chemotherapy often develop a state of immunosuppression and are at risk for opportunistic infections and reactivation of hepatitis and herpes viruses." | 7.74 | Valproic acid related idiosyncratic drug induced hepatotoxicity in a glioblastoma patient treated with temozolomide. ( Hoorens, A; Neyns, B; Stupp, R, 2008) |
| " Hematotoxicity is listed as a frequent adverse drug reaction in the US prescribing information and hepatotoxicity has been reported infrequently in the postmarketing period." | 6.48 | Severe sustained cholestatic hepatitis following temozolomide in a patient with glioblastoma multiforme: case study and review of data from the FDA adverse event reporting system. ( Bronder, E; Garbe, E; Herbst, H; Kauffmann, W; Klimpel, A; Orzechowski, HD; Sarganas, G; Thomae, M, 2012) |
| "Temozolomide is the current standard of therapy for postoperative patients with glioblastoma starting adjuvant radiotherapy." | 4.91 | Severe cholestatic hepatitis due to temozolomide: an adverse drug effect to keep in mind. Case report and review of literature. ( Balducci, N; Biolato, M; Di Napoli, N; Diletto, B; Grieco, A; Miele, L; Tafuri, MA; Vecchio, FM, 2015) |
| "Temozolomide is an alkylating agent used along with concurrent radiation therapy in the treatment of glioblastoma." | 3.83 | Temozolomide-induced biliary ductopenia: a case report. ( Balakrishnan, A; Jaglal, M; Ledford, R, 2016) |
| "Glioblastoma patients undergoing treatment with surgery followed by radiation and temozolomide chemotherapy often develop a state of immunosuppression and are at risk for opportunistic infections and reactivation of hepatitis and herpes viruses." | 3.74 | Valproic acid related idiosyncratic drug induced hepatotoxicity in a glioblastoma patient treated with temozolomide. ( Hoorens, A; Neyns, B; Stupp, R, 2008) |
| " Hematotoxicity is listed as a frequent adverse drug reaction in the US prescribing information and hepatotoxicity has been reported infrequently in the postmarketing period." | 2.48 | Severe sustained cholestatic hepatitis following temozolomide in a patient with glioblastoma multiforme: case study and review of data from the FDA adverse event reporting system. ( Bronder, E; Garbe, E; Herbst, H; Kauffmann, W; Klimpel, A; Orzechowski, HD; Sarganas, G; Thomae, M, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 4 (80.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Grieco, A | 1 |
| Tafuri, MA | 1 |
| Biolato, M | 1 |
| Diletto, B | 1 |
| Di Napoli, N | 1 |
| Balducci, N | 1 |
| Vecchio, FM | 1 |
| Miele, L | 1 |
| Balakrishnan, A | 1 |
| Ledford, R | 1 |
| Jaglal, M | 1 |
| Neyns, B | 1 |
| Hoorens, A | 1 |
| Stupp, R | 1 |
| Sarganas, G | 1 |
| Orzechowski, HD | 1 |
| Klimpel, A | 1 |
| Thomae, M | 1 |
| Kauffmann, W | 1 |
| Herbst, H | 1 |
| Bronder, E | 1 |
| Garbe, E | 1 |
| Zamani, N | 1 |
| Mohammad Alizadeh, A | 1 |
2 reviews available for temozolomide and Cholestasis
| Article | Year |
|---|---|
Severe cholestatic hepatitis due to temozolomide: an adverse drug effect to keep in mind. Case report and review of literature.
Topics: Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemical and Drug Induced Liver Injury; Ch | 2015 |
Severe sustained cholestatic hepatitis following temozolomide in a patient with glioblastoma multiforme: case study and review of data from the FDA adverse event reporting system.
Topics: Adverse Drug Reaction Reporting Systems; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemica | 2012 |
3 other studies available for temozolomide and Cholestasis
| Article | Year |
|---|---|
Temozolomide-induced biliary ductopenia: a case report.
Topics: Antineoplastic Agents, Alkylating; Bile Duct Diseases; Bile Ducts, Intrahepatic; Chemoradiotherapy; | 2016 |
Valproic acid related idiosyncratic drug induced hepatotoxicity in a glioblastoma patient treated with temozolomide.
Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemical and Drug Induced Liver Injury; Chemothe | 2008 |
Drug-induced cholestatic hepatitis: how late can it occur even after the cessation of the culpable drug?
Topics: Acetaminophen; Analgesics, Non-Narcotic; Antineoplastic Agents, Alkylating; Chemical and Drug Induce | 2012 |