Page last updated: 2024-11-04

temozolomide and Central Nervous System Disease

temozolomide has been researched along with Central Nervous System Disease in 2 studies

Research Excerpts

ExcerptRelevanceReference
"Temozolomide is a well-tolerated alkylating agent, that is able to permeate the blood-brain barrier (BBB), and has additive cytotoxicity when given with radiotherapy (RT)."6.71Salvage chemotherapy with temozolomide in primary CNS lymphomas: preliminary results of a phase II trial. ( Abbadessa, A; Bernardi, D; Bordonaro, R; Candela, M; Dell'Oro, S; Ferreri, AJ; Franceschi, E; Latte, G; Mason, W; Pace, A; Perry, J; Reni, M; Stelitano, C; Villa, E; Zaja, F, 2004)
"Temozolomide was well tolerated; there were no treatment withdrawals or dose reductions caused by toxicity."5.43Temozolomide for central nervous system involvement in mycosis fungoides. ( Bird, TG; Child, F; Morris, SL; Wain, EM; Whittaker, S, 2016)
"Temozolomide is a well-tolerated alkylating agent, that is able to permeate the blood-brain barrier (BBB), and has additive cytotoxicity when given with radiotherapy (RT)."2.71Salvage chemotherapy with temozolomide in primary CNS lymphomas: preliminary results of a phase II trial. ( Abbadessa, A; Bernardi, D; Bordonaro, R; Candela, M; Dell'Oro, S; Ferreri, AJ; Franceschi, E; Latte, G; Mason, W; Pace, A; Perry, J; Reni, M; Stelitano, C; Villa, E; Zaja, F, 2004)
"Temozolomide was well tolerated; there were no treatment withdrawals or dose reductions caused by toxicity."1.43Temozolomide for central nervous system involvement in mycosis fungoides. ( Bird, TG; Child, F; Morris, SL; Wain, EM; Whittaker, S, 2016)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (50.00)29.6817
2010's1 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bird, TG1
Whittaker, S1
Wain, EM1
Child, F1
Morris, SL1
Reni, M1
Mason, W1
Zaja, F1
Perry, J1
Franceschi, E1
Bernardi, D1
Dell'Oro, S1
Stelitano, C1
Candela, M1
Abbadessa, A1
Pace, A1
Bordonaro, R1
Latte, G1
Villa, E1
Ferreri, AJ1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Pilot Study Investigating Neoadjuvant Temozolomide-based Proton Chemoradiotherapy for High-Risk Soft Tissue Sarcomas[NCT00881595]Phase 20 participants (Actual)Interventional2009-02-28Withdrawn (stopped due to No patients accrued since study opened)
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

1 trial available for temozolomide and Central Nervous System Disease

ArticleYear
Salvage chemotherapy with temozolomide in primary CNS lymphomas: preliminary results of a phase II trial.
    European journal of cancer (Oxford, England : 1990), 2004, Volume: 40, Issue:11

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Central Nervous System Diseases; Dacarba

2004

Other Studies

1 other study available for temozolomide and Central Nervous System Disease

ArticleYear
Temozolomide for central nervous system involvement in mycosis fungoides.
    International journal of dermatology, 2016, Volume: 55, Issue:7

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Central Nervous System Diseases; Dacarbazine;

2016