Page last updated: 2024-11-04

temozolomide and Carcinoma

temozolomide has been researched along with Carcinoma in 37 studies

Carcinoma: A malignant neoplasm made up of epithelial cells tending to infiltrate the surrounding tissues and give rise to metastases. It is a histological type of neoplasm and not a synonym for cancer.

Research Excerpts

ExcerptRelevanceReference
" Temozolomide (TMZ) is an oral alkylating agent that has shown promise in treating aggressive pituitary adenomas and carcinomas that are resistant to other therapies."8.95Temozolomide therapy for resistant prolactin-secreting pituitary adenomas and carcinomas: a systematic review. ( Ahmad, MM; Aldabas, BS; Aljoaib, NN; Almalki, MH; Alotaibi, MJ; Alshahrani, F; Wahedi, TS, 2017)
"Temozolomide is an alkylating agent used in the treatment of gliomas and, more recently, aggressive pituitary adenomas and carcinomas."8.88Temozolomide in aggressive pituitary adenomas and carcinomas. ( Fadul, CE; Horvath, E; Kovacs, K; Ortiz, LD; Rotondo, F; Scheithauer, BW; Syro, LV; Uribe, H, 2012)
"Despite growing evidence that temozolomide (TMZ) therapy is effective for the treatment of aggressive pituitary tumors (APTs) or carcinomas (PCs), individual therapy decisions remain challenging."7.96Efficacy of Temozolomide Therapy in Patients With Aggressive Pituitary Adenomas and Carcinomas-A German Survey. ( Bojunga, J; Buchfelder, M; Buslei, R; Deutschbein, T; Droste, M; Elbelt, U; Honegger, J; Johanssen, S; Knappe, UJ; Kolenda, H; Lammert, A; Micko, A; Petersenn, S; Ritzel, K; Schlaffer, SM; Strasburger, CJ; Topuzoglu-Müller, T; Unger, N; Vila, G, 2020)
"To evaluate the impact of temozolomide (TMZ) introduction on the survival of patients with pituitary carcinoma (PC) compared to aggressive pituitary adenoma (APA)."7.91Lower all-cause mortality rates in patients harboring pituitary carcinoma following the introduction of temozolomide. ( Aharon-Hananel, G; Badarna, M; Percik, R; Tirosh, A; Uri, I, 2019)
" Descriptions of aggressive pituitary tumors and pituitary carcinomas have increased notably over the last decade following the first report on the successful treatment of pituitary carcinomas using temozolomide."7.83Therapeutic innovations in endocrine diseases - part 3 : temozolomide and future therapeutics for aggressive pituitary tumors and carcinomas. ( Lasolle, H; Raverot, G, 2016)
"We report here a rare case of a young male patient presenting with a Multiple Endocrine Neoplasia Type 1 - prolactin-secreting pituitary carcinoma, controlled long-term after temozolomide withdrawal."7.78Long-term control of a MEN1 prolactin secreting pituitary carcinoma after temozolomide treatment. ( Barlier, A; Barrie, M; Brue, T; Castinetti, F; Conte-Devolx, B; Dufour, H; Morange, I; Philippon, M; Taieb, D, 2012)
"Prolonged administration of adjuvant temozolomide is safe and can be favorable for patients with anaplastic gliomas."7.77Prolonged administration of temozolomide in adult patients with anaplastic glioma. ( Freyschlag, CF; Janzen, E; Lohr, F; Schmieder, K; Seiz, M; Smolczyk, DR; Thomé, C; Tuettenberg, J; Weiss, C; Wenz, F, 2011)
"The case presented here describes the clinical evolution of a pituitary carcinoma from an atypical prolactinoma after temozolomide (TMZ) treatment."7.77A mechanism of acquiring temozolomide resistance during transformation of atypical prolactinoma into prolactin-producing pituitary carcinoma: case report. ( Asano, S; Ishida, Y; Katakami, H; Matsuno, A; Mizutani, A; Murakami, M; Okinaga, H; Ozawa, Y; Takano, K; Yamazaki, K, 2011)
"Temozolomide treatment has a wide range of efficacy in patients with pituitary carcinoma or locally aggressive pituitary adenoma."7.76Salvage therapy with temozolomide in patients with aggressive or metastatic pituitary adenomas: experience in six cases. ( Cangi, MG; Gill, AJ; Losa, M; Mazza, E; McCormack, A; Mortini, P; Motta, M; Reni, M; Talarico, A; Terreni, MR, 2010)
"Eight patients, five with pituitary carcinomas (three prolactin (PRL) and two ACTH) and three with aggressive pituitary tumors (one PRL and two ACTH), all treated with temozolomide administered orally for four to 24 cycles, were included in our French multicenter study."7.76Temozolomide treatment in aggressive pituitary tumors and pituitary carcinomas: a French multicenter experience. ( Assaker, R; Bernier, M; Borson-Chazot, F; Brue, T; Caron, P; Chabre, O; Chanson, P; Cornélius, A; Cortet-Rudelli, C; de Fraipont, F; Dufour, H; Figarella-Branger, D; François, P; Gaillard, S; Jouanneau, E; Muller, M; Passagia, JG; Raverot, G; Salenave, S; Sturm, N; Trouillas, J, 2010)
"Temozolomide (TMZ) has been used in the last 15 years in patients with aggressive pituitary tumors."7.01Knowing when to discontinue Temozolomide therapy in responding aggressive pituitary tumors and carcinomas: a systematic review and Padua (Italy) case series. ( Barbot, M; Bergo, E; Caccese, M; Ceccato, F; Cerretti, G; Lombardi, G; Occhi, G; Padovan, M; Scaroni, C, 2023)
"Aggressive pituitary adenomas (APAs) and pituitary carcinomas (PCs) are challenging for their invasive nature, resistance to treatment and recurrences."6.66Long-course temozolomide in aggressive pituitary adenoma: real-life experience in two tertiary care centers and review of the literature. ( Barbot, M; Bellu, L; Ceccato, F; Gardiman, MP; Lizzul, L; Lombardi, G; Losa, M; Mazza, E; Regazzo, D; Scaroni, C, 2020)
"A significant proportion of pituitary adenomas and carcinomas had low MGMT immunoexpression."6.47Treatment of pituitary neoplasms with temozolomide: a review. ( Cusimano, M; Gonzalez, R; Horvath, E; Kovacs, K; Lau, Q; Lloyd, R; Ortiz, LD; Scheithauer, BW; Syro, LV; Uribe, H, 2011)
"Pituitary adenomas have relatively high expression of vascular endothelial growth factor; therefore, bevacizumab, an antiangiogenic agent, has been used in a small number of aggressive or malignant pituitary tumors after recurrence."5.46Successful treatment of pituitary carcinoma with concurrent radiation, temozolomide, and bevacizumab after resection. ( Hoostal, S; Lou, E; Peterson, RA; SantaCruz, KS; Touma, W; Wiernik, A, 2017)
"Locally aggressive pituitary tumors (LAPT) and pituitary carcinomas respond poorly to conventional therapy and cytotoxic drugs."5.42Long-term outcome and MGMT as a predictive marker in 24 patients with atypical pituitary adenomas and pituitary carcinomas given treatment with temozolomide. ( Andersen, M; Bengtsson, D; Berinder, K; Burman, P; Feldt Rasmussen, U; Hoybye, C; Johannsson, G; Maiter, D; Petersson, M; Ragnarsson, O; Rasmussen, ÅK; Schrøder, HD; van der Lely, AJ, 2015)
"Pituitary carcinomas are rare and neurosurgically challenging lesions, as they commonly relapse after surgical removal."5.36SOM230 (pasireotide) and temozolomide achieve sustained control of tumour progression and ACTH secretion in pituitary carcinoma with widespread metastases. ( Back, W; Bode, H; Brockmann, MA; Hammes, HP; Lammert, A; Seiz, M; Thomé, C, 2010)
"Once temozolomide has failed, there is no recommended treatment option for pituitary carcinomas and aggressive pituitary tumors."5.22Immunotherapy in aggressive pituitary tumors and carcinomas: a systematic review. ( Ilie, MD; Jouanneau, E; Raverot, G; Vasiljevic, A, 2022)
"A single-institution phase II trial of Temodal (temozolomide, SCH52365) in Chinese patients with advance nasopharyngeal carcinoma was undertaken to determine the efficacy and safety of the drug in this population."5.08Phase II study of Temodal in the treatment of patients with advanced nasopharyngeal carcinoma. ( Chan, AT; Johnson, PJ; Kwan, WH; Lai, M; Leung, TW; Mok, TS; Yeo, W, 1998)
" Temozolomide (TMZ) is an oral alkylating agent that has shown promise in treating aggressive pituitary adenomas and carcinomas that are resistant to other therapies."4.95Temozolomide therapy for resistant prolactin-secreting pituitary adenomas and carcinomas: a systematic review. ( Ahmad, MM; Aldabas, BS; Aljoaib, NN; Almalki, MH; Alotaibi, MJ; Alshahrani, F; Wahedi, TS, 2017)
"Temozolomide is an alkylating agent used in the treatment of gliomas and, more recently, aggressive pituitary adenomas and carcinomas."4.88Temozolomide in aggressive pituitary adenomas and carcinomas. ( Fadul, CE; Horvath, E; Kovacs, K; Ortiz, LD; Rotondo, F; Scheithauer, BW; Syro, LV; Uribe, H, 2012)
"After temozolomide failure, no evidence-based treatment is available for pituitary carcinomas (PCs) and aggressive pituitary tumors (APTs)."4.12Real-life efficacy and predictors of response to immunotherapy in pituitary tumors: a cohort study. ( Assie, G; Baussart, B; Cancel, M; Chanson, P; Cortet, C; Cuny, T; Decoudier, B; Deluche, E; Di Stefano, AL; Drui, D; Gaillard, S; Goichot, B; Huillard, O; Ilie, MD; Joncour, A; Larrieu-Ciron, D; Libe, R; Nars, G; Raverot, G; Vasiljevic, A; Villa, C, 2022)
"Despite growing evidence that temozolomide (TMZ) therapy is effective for the treatment of aggressive pituitary tumors (APTs) or carcinomas (PCs), individual therapy decisions remain challenging."3.96Efficacy of Temozolomide Therapy in Patients With Aggressive Pituitary Adenomas and Carcinomas-A German Survey. ( Bojunga, J; Buchfelder, M; Buslei, R; Deutschbein, T; Droste, M; Elbelt, U; Honegger, J; Johanssen, S; Knappe, UJ; Kolenda, H; Lammert, A; Micko, A; Petersenn, S; Ritzel, K; Schlaffer, SM; Strasburger, CJ; Topuzoglu-Müller, T; Unger, N; Vila, G, 2020)
"To evaluate the impact of temozolomide (TMZ) introduction on the survival of patients with pituitary carcinoma (PC) compared to aggressive pituitary adenoma (APA)."3.91Lower all-cause mortality rates in patients harboring pituitary carcinoma following the introduction of temozolomide. ( Aharon-Hananel, G; Badarna, M; Percik, R; Tirosh, A; Uri, I, 2019)
"To collect outcome data in a large cohort of patients with aggressive pituitary tumours (APT)/carcinomas (PC) and specifically report effects of temozolomide (TMZ) treatment."3.88Treatment of aggressive pituitary tumours and carcinomas: results of a European Society of Endocrinology (ESE) survey 2016. ( Burman, P; Dekkers, OM; McCormack, A; Petersenn, S; Popovic, V; Raverot, G; Trouillas, J, 2018)
" Descriptions of aggressive pituitary tumors and pituitary carcinomas have increased notably over the last decade following the first report on the successful treatment of pituitary carcinomas using temozolomide."3.83Therapeutic innovations in endocrine diseases - part 3 : temozolomide and future therapeutics for aggressive pituitary tumors and carcinomas. ( Lasolle, H; Raverot, G, 2016)
"We report here a rare case of a young male patient presenting with a Multiple Endocrine Neoplasia Type 1 - prolactin-secreting pituitary carcinoma, controlled long-term after temozolomide withdrawal."3.78Long-term control of a MEN1 prolactin secreting pituitary carcinoma after temozolomide treatment. ( Barlier, A; Barrie, M; Brue, T; Castinetti, F; Conte-Devolx, B; Dufour, H; Morange, I; Philippon, M; Taieb, D, 2012)
"The case presented here describes the clinical evolution of a pituitary carcinoma from an atypical prolactinoma after temozolomide (TMZ) treatment."3.77A mechanism of acquiring temozolomide resistance during transformation of atypical prolactinoma into prolactin-producing pituitary carcinoma: case report. ( Asano, S; Ishida, Y; Katakami, H; Matsuno, A; Mizutani, A; Murakami, M; Okinaga, H; Ozawa, Y; Takano, K; Yamazaki, K, 2011)
"Prolonged administration of adjuvant temozolomide is safe and can be favorable for patients with anaplastic gliomas."3.77Prolonged administration of temozolomide in adult patients with anaplastic glioma. ( Freyschlag, CF; Janzen, E; Lohr, F; Schmieder, K; Seiz, M; Smolczyk, DR; Thomé, C; Tuettenberg, J; Weiss, C; Wenz, F, 2011)
"MGMT promoter hypermethylation of aggressive pituitary adenomas and pituitary carcinomas and low protein expression are implicated in improved response to treatment with temozolomide (TMZ)."3.77MGMT promoter methylation and immunoexpression in aggressive pituitary adenomas and carcinomas. ( Erickson, D; Fealey, M; Horvath, E; Kovacs, K; Kros, JM; Lau, Q; Lloyd, RV; Salehi, F; Scheithauer, BW, 2011)
"Eight patients, five with pituitary carcinomas (three prolactin (PRL) and two ACTH) and three with aggressive pituitary tumors (one PRL and two ACTH), all treated with temozolomide administered orally for four to 24 cycles, were included in our French multicenter study."3.76Temozolomide treatment in aggressive pituitary tumors and pituitary carcinomas: a French multicenter experience. ( Assaker, R; Bernier, M; Borson-Chazot, F; Brue, T; Caron, P; Chabre, O; Chanson, P; Cornélius, A; Cortet-Rudelli, C; de Fraipont, F; Dufour, H; Figarella-Branger, D; François, P; Gaillard, S; Jouanneau, E; Muller, M; Passagia, JG; Raverot, G; Salenave, S; Sturm, N; Trouillas, J, 2010)
"Temozolomide treatment has a wide range of efficacy in patients with pituitary carcinoma or locally aggressive pituitary adenoma."3.76Salvage therapy with temozolomide in patients with aggressive or metastatic pituitary adenomas: experience in six cases. ( Cangi, MG; Gill, AJ; Losa, M; Mazza, E; McCormack, A; Mortini, P; Motta, M; Reni, M; Talarico, A; Terreni, MR, 2010)
" These studies evaluated the antitumor efficacy of CEP-7055 using orthotopic models of glioblastoma and colon carcinoma in combination with temozolomide, and irinotecan and oxaliplatin, respectively, for their effects on primary and metastatic tumor burden and median survival."3.73The effects of the oral, pan-VEGF-R kinase inhibitor CEP-7055 and chemotherapy in orthotopic models of glioblastoma and colon carcinoma in mice. ( Hunter, K; Jones-Bolin, S; Klein-Szanto, A; Ruggeri, B; Zhao, H, 2006)
"Temozolomide (TMZ) has been used in the last 15 years in patients with aggressive pituitary tumors."3.01Knowing when to discontinue Temozolomide therapy in responding aggressive pituitary tumors and carcinomas: a systematic review and Padua (Italy) case series. ( Barbot, M; Bergo, E; Caccese, M; Ceccato, F; Cerretti, G; Lombardi, G; Occhi, G; Padovan, M; Scaroni, C, 2023)
"Pituitary tumors are generally benign, although in rare cases aggressive pituitary tumors (APTs) and carcinomas present important diagnostic and therapeutic challenges and are associated with a high mortality rate."2.82Aggressive corticotroph tumors and carcinomas. ( Ilie, MD; Jouanneau, E; Lasolle, H; Raverot, G; Vasiljevic, A, 2022)
"Cushing's disease is a syndromic pathological condition caused by adrenocorticotropic hormone (ACTH)-secreting pituitary adenomas (ACTHomas) mediated by hypercortisolemia."2.72Aggressive Cushing's Disease: Molecular Pathology and Its Therapeutic Approach. ( Fukuoka, H; Nakao, T; Ogawa, W; Yamamoto, M, 2021)
"Aggressive pituitary adenomas (APAs) and pituitary carcinomas (PCs) are challenging for their invasive nature, resistance to treatment and recurrences."2.66Long-course temozolomide in aggressive pituitary adenoma: real-life experience in two tertiary care centers and review of the literature. ( Barbot, M; Bellu, L; Ceccato, F; Gardiman, MP; Lizzul, L; Lombardi, G; Losa, M; Mazza, E; Regazzo, D; Scaroni, C, 2020)
"A significant proportion of pituitary adenomas and carcinomas had low MGMT immunoexpression."2.47Treatment of pituitary neoplasms with temozolomide: a review. ( Cusimano, M; Gonzalez, R; Horvath, E; Kovacs, K; Lau, Q; Lloyd, R; Ortiz, LD; Scheithauer, BW; Syro, LV; Uribe, H, 2011)
"The majority of anterior pituitary tumors behave benignly, that is, they grow slowly and do not metastasize, and were therefore called adenomas."1.91Aggressive pituitary tumors (PitNETs). ( Nishioka, H, 2023)
"Temozolomide treatment in 156/171 patients resulted in complete response in 9."1.72Aggressive pituitary tumours and carcinomas, characteristics and management of 171 patients. ( Burman, P; Dekkers, OM; Losa, M; McCormack, A; Petersenn, S; Popovic, V; Raverot, G; Theodoropoulou, M; Trouillas, J, 2022)
"Pituitary adenomas have relatively high expression of vascular endothelial growth factor; therefore, bevacizumab, an antiangiogenic agent, has been used in a small number of aggressive or malignant pituitary tumors after recurrence."1.46Successful treatment of pituitary carcinoma with concurrent radiation, temozolomide, and bevacizumab after resection. ( Hoostal, S; Lou, E; Peterson, RA; SantaCruz, KS; Touma, W; Wiernik, A, 2017)
"Locally aggressive pituitary tumors (LAPT) and pituitary carcinomas respond poorly to conventional therapy and cytotoxic drugs."1.42Long-term outcome and MGMT as a predictive marker in 24 patients with atypical pituitary adenomas and pituitary carcinomas given treatment with temozolomide. ( Andersen, M; Bengtsson, D; Berinder, K; Burman, P; Feldt Rasmussen, U; Hoybye, C; Johannsson, G; Maiter, D; Petersson, M; Ragnarsson, O; Rasmussen, ÅK; Schrøder, HD; van der Lely, AJ, 2015)
"Nasopharyngeal carcinoma is a rare but highly invasive cancer."1.39PARP1 is overexpressed in nasopharyngeal carcinoma and its inhibition enhances radiotherapy. ( Chen, H; Cheung, F; Chow, JP; Li Lung, M; Man, WY; Mao, M; Nicholls, J; Poon, RY; Tsao, SW, 2013)
"Most drugs used for colorectal cancer therapy induce DNA-alkylation damage, which is primarily repaired by the base excision repair (BER) pathway."1.37DNA polymerase β as a novel target for chemotherapeutic intervention of colorectal cancer. ( Aneja, R; Banerjee, S; Jaiswal, AS; Narayan, S; Ostrov, DA; Sarkar, FH, 2011)
"Pituitary carcinomas are rare and neurosurgically challenging lesions, as they commonly relapse after surgical removal."1.36SOM230 (pasireotide) and temozolomide achieve sustained control of tumour progression and ACTH secretion in pituitary carcinoma with widespread metastases. ( Back, W; Bode, H; Brockmann, MA; Hammes, HP; Lammert, A; Seiz, M; Thomé, C, 2010)

Research

Studies (37)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (2.70)18.2507
2000's5 (13.51)29.6817
2010's21 (56.76)24.3611
2020's10 (27.03)2.80

Authors

AuthorsStudies
Ilie, MD3
Vasiljevic, A4
Jouanneau, E4
Raverot, G9
Lasolle, H3
Burman, P4
Trouillas, J4
Losa, M4
McCormack, A4
Petersenn, S4
Popovic, V3
Theodoropoulou, M2
Dekkers, OM3
Villa, C2
Cuny, T1
Cortet, C2
Assie, G2
Baussart, B1
Cancel, M1
Chanson, P3
Decoudier, B1
Deluche, E1
Di Stefano, AL1
Drui, D1
Gaillard, S3
Goichot, B1
Huillard, O1
Joncour, A1
Larrieu-Ciron, D1
Libe, R1
Nars, G1
Nishioka, H1
Padovan, M1
Cerretti, G1
Caccese, M1
Barbot, M2
Bergo, E1
Occhi, G1
Scaroni, C2
Lombardi, G2
Ceccato, F2
Elbelt, U1
Schlaffer, SM1
Buchfelder, M1
Knappe, UJ1
Vila, G1
Micko, A1
Deutschbein, T1
Unger, N1
Lammert, A2
Topuzoglu-Müller, T1
Bojunga, J1
Droste, M1
Johanssen, S1
Kolenda, H1
Ritzel, K1
Buslei, R1
Strasburger, CJ1
Honegger, J1
Lizzul, L1
Gardiman, MP1
Regazzo, D1
Bellu, L1
Mazza, E2
Yamamoto, M1
Nakao, T1
Ogawa, W1
Fukuoka, H1
Castinetti, F2
Cloix, L1
Caron, P2
Delemer, B1
Desailloud, R1
Jublanc, C1
Lebrun-Frenay, C1
Sadoul, JL1
Taillandier, L1
Batisse-Lignier, M1
Bonnet, F1
Bourcigaux, N1
Bresson, D1
Chabre, O2
Garcia, C1
Haissaguerre, M1
Reznik, Y1
Borot, S1
Almalki, MH1
Aljoaib, NN1
Alotaibi, MJ1
Aldabas, BS1
Wahedi, TS1
Ahmad, MM1
Alshahrani, F1
Aharon-Hananel, G1
Percik, R1
Badarna, M1
Uri, I1
Tirosh, A1
Chow, JP1
Man, WY1
Mao, M1
Chen, H1
Cheung, F1
Nicholls, J1
Tsao, SW1
Li Lung, M1
Poon, RY1
Minniti, G1
Scaringi, C1
Lanzetta, G1
Bozzao, A1
Romano, A1
De Sanctis, V1
Valeriani, M1
Osti, M1
Enrici, RM1
Bengtsson, D1
Schrøder, HD1
Andersen, M1
Maiter, D1
Berinder, K1
Feldt Rasmussen, U1
Rasmussen, ÅK1
Johannsson, G1
Hoybye, C1
van der Lely, AJ1
Petersson, M1
Ragnarsson, O1
Chen, TC1
Cho, HY1
Wang, W1
Wetzel, SJ1
Singh, A1
Nguyen, J1
Hofman, FM1
Schönthal, AH1
Touma, W1
Hoostal, S1
Peterson, RA1
Wiernik, A1
SantaCruz, KS1
Lou, E1
Lozier, AP1
Arbaje, YM1
Scheithauer, BW4
Bode, H1
Seiz, M2
Brockmann, MA1
Back, W1
Hammes, HP1
Thomé, C2
Sturm, N1
de Fraipont, F1
Muller, M1
Salenave, S1
Cortet-Rudelli, C1
Assaker, R1
Dufour, H2
François, P1
Passagia, JG1
Bernier, M1
Cornélius, A1
Figarella-Branger, D1
Borson-Chazot, F1
Brue, T2
Syro, LV2
Ortiz, LD2
Lloyd, R1
Lau, Q2
Gonzalez, R1
Uribe, H2
Cusimano, M1
Kovacs, K3
Horvath, E3
Terreni, MR1
Gill, AJ1
Motta, M1
Cangi, MG1
Talarico, A1
Mortini, P1
Reni, M1
Jaiswal, AS1
Banerjee, S1
Aneja, R1
Sarkar, FH1
Ostrov, DA1
Narayan, S1
Salehi, F1
Kros, JM1
Fealey, M1
Erickson, D1
Lloyd, RV1
Murakami, M1
Mizutani, A1
Asano, S1
Katakami, H1
Ozawa, Y1
Yamazaki, K1
Ishida, Y1
Takano, K1
Okinaga, H1
Matsuno, A1
Freyschlag, CF1
Smolczyk, DR1
Janzen, E1
Schmieder, K1
Lohr, F1
Wenz, F1
Weiss, C1
Tuettenberg, J1
Philippon, M1
Morange, I1
Barrie, M1
Barlier, A1
Taieb, D1
Conte-Devolx, B1
Rotondo, F1
Fadul, CE1
Dixit, S1
Salvage, D1
Rajaraman, C1
Hingorani, M1
Rowland-Hill, C1
Lim, S1
Shahinian, H1
Maya, MM1
Yong, W1
Heaney, AP1
Jones-Bolin, S1
Zhao, H1
Hunter, K1
Klein-Szanto, A1
Ruggeri, B1
Siker, ML1
Chakravarti, A1
Mehta, MP1
Caporali, S1
Levati, L1
Starace, G1
Ragone, G1
Bonmassar, E1
Alvino, E1
D'Atri, S1
Chan, AT1
Leung, TW1
Kwan, WH1
Mok, TS1
Yeo, W1
Lai, M1
Johnson, PJ1

Reviews

9 reviews available for temozolomide and Carcinoma

ArticleYear
Immunotherapy in aggressive pituitary tumors and carcinomas: a systematic review.
    Endocrine-related cancer, 2022, 05-27, Volume: 29, Issue:7

    Topics: Carcinoma; Humans; Immune Checkpoint Inhibitors; Immunotherapy; Pituitary Neoplasms; Temozolomide

2022
Aggressive corticotroph tumors and carcinomas.
    Journal of neuroendocrinology, 2022, Volume: 34, Issue:8

    Topics: Adenoma; Carcinoma; Corticotrophs; Humans; Pituitary Neoplasms; Temozolomide

2022
Knowing when to discontinue Temozolomide therapy in responding aggressive pituitary tumors and carcinomas: a systematic review and Padua (Italy) case series.
    Expert review of endocrinology & metabolism, 2023, Volume: 18, Issue:2

    Topics: Adenoma; Antineoplastic Agents, Alkylating; Carcinoma; Dacarbazine; Humans; Pituitary Neoplasms; Tem

2023
Long-course temozolomide in aggressive pituitary adenoma: real-life experience in two tertiary care centers and review of the literature.
    Pituitary, 2020, Volume: 23, Issue:4

    Topics: ACTH-Secreting Pituitary Adenoma; Adenoma; Adult; Aged; Antineoplastic Agents, Alkylating; Carcinoma

2020
Aggressive Cushing's Disease: Molecular Pathology and Its Therapeutic Approach.
    Frontiers in endocrinology, 2021, Volume: 12

    Topics: ACTH-Secreting Pituitary Adenoma; Adenoma; Adrenocorticotropic Hormone; Carcinoma; Dopamine Agonists

2021
Temozolomide therapy for resistant prolactin-secreting pituitary adenomas and carcinomas: a systematic review.
    Hormones (Athens, Greece), 2017, Volume: 16, Issue:2

    Topics: Antineoplastic Agents, Alkylating; Carcinoma; Dacarbazine; Humans; Pituitary Neoplasms; Prolactinoma

2017
Treatment of pituitary neoplasms with temozolomide: a review.
    Cancer, 2011, Feb-01, Volume: 117, Issue:3

    Topics: Adenoma; Antineoplastic Agents, Alkylating; Biomarkers, Tumor; Carcinoma; Dacarbazine; DNA Modificat

2011
Temozolomide in aggressive pituitary adenomas and carcinomas.
    Clinics (Sao Paulo, Brazil), 2012, Volume: 67 Suppl 1

    Topics: Adenoma; Antineoplastic Agents, Alkylating; Carcinoma; Dacarbazine; Humans; Pituitary Neoplasms; Tem

2012
Should concomitant and adjuvant treatment with temozolomide be used as standard therapy in patients with anaplastic glioma?
    Critical reviews in oncology/hematology, 2006, Volume: 60, Issue:2

    Topics: Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neoplasms; Carcinoma; Chemotherapy, Adjuvant;

2006

Trials

2 trials available for temozolomide and Carcinoma

ArticleYear
Whole brain reirradiation and concurrent temozolomide in patients with brain metastases.
    Journal of neuro-oncology, 2014, Volume: 118, Issue:2

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Breast Neoplasms; Carcinoma; Carcin

2014
Phase II study of Temodal in the treatment of patients with advanced nasopharyngeal carcinoma.
    Cancer chemotherapy and pharmacology, 1998, Volume: 42, Issue:3

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Carcinoma; Dacarbazine; Female; Humans; Male; Middle

1998

Other Studies

26 other studies available for temozolomide and Carcinoma

ArticleYear
Aggressive pituitary tumours and carcinomas, characteristics and management of 171 patients.
    European journal of endocrinology, 2022, Oct-01, Volume: 187, Issue:4

    Topics: Adenoma; Adrenocorticotropic Hormone; Bevacizumab; Carcinoma; Female; Humans; Immune Checkpoint Inhi

2022
Real-life efficacy and predictors of response to immunotherapy in pituitary tumors: a cohort study.
    European journal of endocrinology, 2022, Nov-01, Volume: 187, Issue:5

    Topics: B7-H1 Antigen; Carcinoma; Cohort Studies; Humans; Immune Checkpoint Inhibitors; Immunotherapy; Pitui

2022
Aggressive pituitary tumors (PitNETs).
    Endocrine journal, 2023, Mar-28, Volume: 70, Issue:3

    Topics: Adenoma; Carcinoma; Humans; Neuroendocrine Tumors; Pituitary Neoplasms; Temozolomide

2023
Initial pathology in aggressive pituitary tumours and carcinomas: 2b or not 2b?-that is the question.
    European journal of endocrinology, 2023, 04-05, Volume: 188, Issue:4

    Topics: Carcinoma; Dacarbazine; Humans; Pituitary Neoplasms; Temozolomide

2023
Efficacy of Temozolomide Therapy in Patients With Aggressive Pituitary Adenomas and Carcinomas-A German Survey.
    The Journal of clinical endocrinology and metabolism, 2020, 03-01, Volume: 105, Issue:3

    Topics: Adenoma; Adult; Antineoplastic Agents, Alkylating; Carcinoma; Female; Germany; Humans; Male; Middle

2020
Temozolomide treatment can improve overall survival in aggressive pituitary tumors and pituitary carcinomas.
    European journal of endocrinology, 2017, Volume: 176, Issue:6

    Topics: ACTH-Secreting Pituitary Adenoma; Adult; Antineoplastic Agents, Alkylating; Carcinoma; Chemoradiothe

2017
Treatment of aggressive pituitary tumours and carcinomas: results of a European Society of Endocrinology (ESE) survey 2016.
    European journal of endocrinology, 2018, Volume: 178, Issue:3

    Topics: Adenoma; Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemoth

2018
Lower all-cause mortality rates in patients harboring pituitary carcinoma following the introduction of temozolomide.
    Endocrine, 2019, Volume: 65, Issue:2

    Topics: Adenoma; Aged; Antineoplastic Agents, Alkylating; Carcinoma; Female; Humans; Israel; Male; Middle Ag

2019
PARP1 is overexpressed in nasopharyngeal carcinoma and its inhibition enhances radiotherapy.
    Molecular cancer therapeutics, 2013, Volume: 12, Issue:11

    Topics: Adult; Aged; Animals; Antineoplastic Agents; Carcinoma; Cell Line; Cell Proliferation; Combined Moda

2013
Long-term outcome and MGMT as a predictive marker in 24 patients with atypical pituitary adenomas and pituitary carcinomas given treatment with temozolomide.
    The Journal of clinical endocrinology and metabolism, 2015, Volume: 100, Issue:4

    Topics: Adenoma; Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Biomarkers, Pharmacological; Bi

2015
Chemotherapeutic effect of a novel temozolomide analog on nasopharyngeal carcinoma in vitro and in vivo.
    Journal of biomedical science, 2015, Aug-19, Volume: 22

    Topics: Animals; Carcinoma; Dacarbazine; DNA Modification Methylases; DNA Repair Enzymes; Humans; Mice; Mice

2015
Therapeutic innovations in endocrine diseases - part 3 : temozolomide and future therapeutics for aggressive pituitary tumors and carcinomas.
    Presse medicale (Paris, France : 1983), 2016, Volume: 45, Issue:6 Pt 2

    Topics: Antineoplastic Agents, Alkylating; Carcinoma; Dacarbazine; Forecasting; Humans; Pituitary Neoplasms;

2016
Successful treatment of pituitary carcinoma with concurrent radiation, temozolomide, and bevacizumab after resection.
    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2017, Volume: 41

    Topics: Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Carc

2017
Supratentorial, extraventricular choroid plexus carcinoma in an adult: case report.
    Neurosurgery, 2009, Volume: 65, Issue:4

    Topics: Aged; Antineoplastic Agents, Alkylating; Brain; Carcinoma; Choroid Plexus; Choroid Plexus Neoplasms;

2009
SOM230 (pasireotide) and temozolomide achieve sustained control of tumour progression and ACTH secretion in pituitary carcinoma with widespread metastases.
    Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association, 2010, Volume: 118, Issue:10

    Topics: Adrenocorticotropic Hormone; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Hormonal; Ant

2010
Temozolomide treatment in aggressive pituitary tumors and pituitary carcinomas: a French multicenter experience.
    The Journal of clinical endocrinology and metabolism, 2010, Volume: 95, Issue:10

    Topics: ACTH-Secreting Pituitary Adenoma; Adult; Antineoplastic Agents, Alkylating; Carcinoma; Dacarbazine;

2010
Salvage therapy with temozolomide in patients with aggressive or metastatic pituitary adenomas: experience in six cases.
    European journal of endocrinology, 2010, Volume: 163, Issue:6

    Topics: Adenoma; Antineoplastic Agents, Alkylating; Carcinoma; Dacarbazine; Female; Humans; Male; Middle Age

2010
DNA polymerase β as a novel target for chemotherapeutic intervention of colorectal cancer.
    PloS one, 2011, Feb-02, Volume: 6, Issue:2

    Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Caco-2 Cells; Carcin

2011
MGMT promoter methylation and immunoexpression in aggressive pituitary adenomas and carcinomas.
    Journal of neuro-oncology, 2011, Volume: 104, Issue:3

    Topics: Adenoma; Adolescent; Adult; Antineoplastic Agents, Alkylating; Carcinoma; Dacarbazine; DNA Methylati

2011
A mechanism of acquiring temozolomide resistance during transformation of atypical prolactinoma into prolactin-producing pituitary carcinoma: case report.
    Neurosurgery, 2011, Volume: 68, Issue:6

    Topics: Antineoplastic Agents, Alkylating; Carcinoma; Cell Transformation, Neoplastic; Dacarbazine; DNA Modi

2011
Prolonged administration of temozolomide in adult patients with anaplastic glioma.
    Anticancer research, 2011, Volume: 31, Issue:11

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Carcinoma; Dacarbazine; Disease Pro

2011
Long-term control of a MEN1 prolactin secreting pituitary carcinoma after temozolomide treatment.
    Annales d'endocrinologie, 2012, Volume: 73, Issue:3

    Topics: Adult; Antineoplastic Agents; Carcinoma; Combined Modality Therapy; Cranial Irradiation; Dacarbazine

2012
Hypernatremia-associated myelinolysis following the management of sepsis in a patient with glioblastoma treated with radiotherapy and temozolomide.
    Acta neurologica Belgica, 2013, Volume: 113, Issue:4

    Topics: Antineoplastic Agents; Brain Diseases; Brain Neoplasms; Carcinoma; Carcinoma, Papillary; Dacarbazine

2013
Temozolomide: a novel treatment for pituitary carcinoma.
    The Lancet. Oncology, 2006, Volume: 7, Issue:6

    Topics: Aged; Antineoplastic Agents, Alkylating; Carcinoma; Combined Modality Therapy; Dacarbazine; Humans;

2006
The effects of the oral, pan-VEGF-R kinase inhibitor CEP-7055 and chemotherapy in orthotopic models of glioblastoma and colon carcinoma in mice.
    Molecular cancer therapeutics, 2006, Volume: 5, Issue:7

    Topics: Administration, Oral; Animals; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Carbazo

2006
AKT is activated in an ataxia-telangiectasia and Rad3-related-dependent manner in response to temozolomide and confers protection against drug-induced cell growth inhibition.
    Molecular pharmacology, 2008, Volume: 74, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Ataxia Telangiectasia Mutated Proteins; B-Lymphocytes; Breast Neo

2008