Page last updated: 2024-11-04

temozolomide and Cancer of Head

temozolomide has been researched along with Cancer of Head in 2 studies

Research

Studies (2)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	1 (50.00)	24.3611
2020's	1 (50.00)	2.80

Authors

Authors	Studies
Pfau, LC	1
Glasow, A	1
Seidel, C	1
Patties, I	1
Hochhauser, D	1
Glynne-Jones, R	1
Potter, V	1
Grávalos, C	1
Doyle, TJ	1
Pathiraja, K	1
Zhang, Q	1
Zhang, L	1
Sausville, EA	1

Clinical Trials (5)

Trial Overview

Trial	Phase	Enrollment	Study Type	Start Date	Status
NIVOLUMAB Plus IPILIMUMAB and TEMOZOLOMIDE in Combination in Microsatellite Stable (MSS), MGMT Silenced Metastatic Colorectal Cancer (mCRC): the MAYA Study[NCT03832621]	Phase 2	135 participants (Actual)	Interventional	2019-03-25	Completed
Multicenter Phase II Study of Preoperative Chemoradiotherapy With CApecitabine Plus Temozolomide in Patients With MGMT Silenced and Microsatellite Stable Locally Advanced RecTal Cancer: the CATARTIC Trial[NCT05136326]	Phase 2	21 participants (Anticipated)	Interventional	2021-12-01	Recruiting
A Phase 2 Study of Temozolomide (SCH 52365) in Subjects With Advanced Aerodigestive Tract Cancers Selected for Methylation of O6-Methyl-Guanine-DNA Methyltransferase (MGMT) Promoter[NCT00423150]	Phase 2	86 participants (Actual)	Interventional	2007-01-26	Terminated
Phase 1b Trial of 5-fluorouracil, Leucovorin, Irinotecan in Combination With Temozolomide (FLIRT) and Bevacizumab for the First-line Treatment of Patients With MGMT Silenced, Microsatellite Stable Metastatic Colorectal Cancer.[NCT04689347]	Phase 1	18 participants (Anticipated)	Interventional	2021-01-01	Recruiting
Temozolomide and Irinotecan Consolidation in Patients With MGMT Silenced, Microsatellite Stable Colorectal Cancer With Persistence of Minimal Residual Disease in Liquid Biopsy After Standard Adjuvant Chemotherapy: the ERASE-TMZ Study[NCT05031975]	Phase 2	35 participants (Anticipated)	Interventional	2022-05-02	Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Tumor Responses (Complete and Partial Response)

"Tumor response rate was based on Response Evaluation Criteria in Solid Tumors (RECIST).~Complete Response (CR): Disappearance of all target lesions.~Partial Response (PR): At least a 30% decrease in the sum of the longest diameter (LD) of target lesions, taking as reference the baseline sum LD." (NCT00423150)
Timeframe: From start of treatment until participant's disease progression, intolerable toxicity or death, which ever comes first

Intervention	Participants (Number)
	Number of participants with Complete Response	Number of participants with Partial Response
Temozolomide	0	5

Trials

1 trial available for temozolomide and Cancer of Head

Article	Year
A phase II study of temozolomide in patients with advanced aerodigestive tract and colorectal cancers and methylation of the O6-methylguanine-DNA methyltransferase promoter. Molecular cancer therapeutics, 2013, Volume: 12, Issue:5 Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Colorectal Neoplasms; Dacarbazine	2013
A phase II study of temozolomide in patients with advanced aerodigestive tract and colorectal cancers and methylation of the O6-methylguanine-DNA methyltransferase promoter. Molecular cancer therapeutics, 2013, Volume: 12, Issue:5 Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Colorectal Neoplasms; Dacarbazine	2013
A phase II study of temozolomide in patients with advanced aerodigestive tract and colorectal cancers and methylation of the O6-methylguanine-DNA methyltransferase promoter. Molecular cancer therapeutics, 2013, Volume: 12, Issue:5 Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Colorectal Neoplasms; Dacarbazine	2013
A phase II study of temozolomide in patients with advanced aerodigestive tract and colorectal cancers and methylation of the O6-methylguanine-DNA methyltransferase promoter. Molecular cancer therapeutics, 2013, Volume: 12, Issue:5 Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Colorectal Neoplasms; Dacarbazine	2013
A phase II study of temozolomide in patients with advanced aerodigestive tract and colorectal cancers and methylation of the O6-methylguanine-DNA methyltransferase promoter. Molecular cancer therapeutics, 2013, Volume: 12, Issue:5 Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Colorectal Neoplasms; Dacarbazine	2013
A phase II study of temozolomide in patients with advanced aerodigestive tract and colorectal cancers and methylation of the O6-methylguanine-DNA methyltransferase promoter. Molecular cancer therapeutics, 2013, Volume: 12, Issue:5 Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Colorectal Neoplasms; Dacarbazine	2013
A phase II study of temozolomide in patients with advanced aerodigestive tract and colorectal cancers and methylation of the O6-methylguanine-DNA methyltransferase promoter. Molecular cancer therapeutics, 2013, Volume: 12, Issue:5 Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Colorectal Neoplasms; Dacarbazine	2013
A phase II study of temozolomide in patients with advanced aerodigestive tract and colorectal cancers and methylation of the O6-methylguanine-DNA methyltransferase promoter. Molecular cancer therapeutics, 2013, Volume: 12, Issue:5 Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Colorectal Neoplasms; Dacarbazine	2013
A phase II study of temozolomide in patients with advanced aerodigestive tract and colorectal cancers and methylation of the O6-methylguanine-DNA methyltransferase promoter. Molecular cancer therapeutics, 2013, Volume: 12, Issue:5 Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Colorectal Neoplasms; Dacarbazine	2013
A phase II study of temozolomide in patients with advanced aerodigestive tract and colorectal cancers and methylation of the O6-methylguanine-DNA methyltransferase promoter. Molecular cancer therapeutics, 2013, Volume: 12, Issue:5 Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Colorectal Neoplasms; Dacarbazine	2013
A phase II study of temozolomide in patients with advanced aerodigestive tract and colorectal cancers and methylation of the O6-methylguanine-DNA methyltransferase promoter. Molecular cancer therapeutics, 2013, Volume: 12, Issue:5 Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Colorectal Neoplasms; Dacarbazine	2013
A phase II study of temozolomide in patients with advanced aerodigestive tract and colorectal cancers and methylation of the O6-methylguanine-DNA methyltransferase promoter. Molecular cancer therapeutics, 2013, Volume: 12, Issue:5 Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Colorectal Neoplasms; Dacarbazine	2013
A phase II study of temozolomide in patients with advanced aerodigestive tract and colorectal cancers and methylation of the O6-methylguanine-DNA methyltransferase promoter. Molecular cancer therapeutics, 2013, Volume: 12, Issue:5 Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Colorectal Neoplasms; Dacarbazine	2013
A phase II study of temozolomide in patients with advanced aerodigestive tract and colorectal cancers and methylation of the O6-methylguanine-DNA methyltransferase promoter. Molecular cancer therapeutics, 2013, Volume: 12, Issue:5 Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Colorectal Neoplasms; Dacarbazine	2013
A phase II study of temozolomide in patients with advanced aerodigestive tract and colorectal cancers and methylation of the O6-methylguanine-DNA methyltransferase promoter. Molecular cancer therapeutics, 2013, Volume: 12, Issue:5 Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Colorectal Neoplasms; Dacarbazine	2013
A phase II study of temozolomide in patients with advanced aerodigestive tract and colorectal cancers and methylation of the O6-methylguanine-DNA methyltransferase promoter. Molecular cancer therapeutics, 2013, Volume: 12, Issue:5 Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Colorectal Neoplasms; Dacarbazine	2013
A phase II study of temozolomide in patients with advanced aerodigestive tract and colorectal cancers and methylation of the O6-methylguanine-DNA methyltransferase promoter. Molecular cancer therapeutics, 2013, Volume: 12, Issue:5 Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Colorectal Neoplasms; Dacarbazine	2013
A phase II study of temozolomide in patients with advanced aerodigestive tract and colorectal cancers and methylation of the O6-methylguanine-DNA methyltransferase promoter. Molecular cancer therapeutics, 2013, Volume: 12, Issue:5 Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Colorectal Neoplasms; Dacarbazine	2013
A phase II study of temozolomide in patients with advanced aerodigestive tract and colorectal cancers and methylation of the O6-methylguanine-DNA methyltransferase promoter. Molecular cancer therapeutics, 2013, Volume: 12, Issue:5 Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Colorectal Neoplasms; Dacarbazine	2013
A phase II study of temozolomide in patients with advanced aerodigestive tract and colorectal cancers and methylation of the O6-methylguanine-DNA methyltransferase promoter. Molecular cancer therapeutics, 2013, Volume: 12, Issue:5 Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Colorectal Neoplasms; Dacarbazine	2013
A phase II study of temozolomide in patients with advanced aerodigestive tract and colorectal cancers and methylation of the O6-methylguanine-DNA methyltransferase promoter. Molecular cancer therapeutics, 2013, Volume: 12, Issue:5 Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Colorectal Neoplasms; Dacarbazine	2013
A phase II study of temozolomide in patients with advanced aerodigestive tract and colorectal cancers and methylation of the O6-methylguanine-DNA methyltransferase promoter. Molecular cancer therapeutics, 2013, Volume: 12, Issue:5 Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Colorectal Neoplasms; Dacarbazine	2013
A phase II study of temozolomide in patients with advanced aerodigestive tract and colorectal cancers and methylation of the O6-methylguanine-DNA methyltransferase promoter. Molecular cancer therapeutics, 2013, Volume: 12, Issue:5 Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Colorectal Neoplasms; Dacarbazine	2013
A phase II study of temozolomide in patients with advanced aerodigestive tract and colorectal cancers and methylation of the O6-methylguanine-DNA methyltransferase promoter. Molecular cancer therapeutics, 2013, Volume: 12, Issue:5 Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Colorectal Neoplasms; Dacarbazine	2013
A phase II study of temozolomide in patients with advanced aerodigestive tract and colorectal cancers and methylation of the O6-methylguanine-DNA methyltransferase promoter. Molecular cancer therapeutics, 2013, Volume: 12, Issue:5 Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Colorectal Neoplasms; Dacarbazine	2013

Other Studies

1 other study available for temozolomide and Cancer of Head

Article	Year
Imidazolyl Ethanamide Pentandioic Acid (IEPA) as Potential Radical Scavenger during Tumor Therapy in Human Hematopoietic Stem Cells. Molecules (Basel, Switzerland), 2023, Feb-21, Volume: 28, Issue:5 Topics: Cytokines; Glioblastoma; Head and Neck Neoplasms; Hematopoietic Stem Cells; Humans; Reactive Oxygen	2023