temozolomide has been researched along with Cancer, Second Primary in 23 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| "The alkylating agent temozolomide (TMZ) is widely used for the treatment of gliomas." | 9.17 | Secondary hematological malignancies associated with temozolomide in patients with glioma. ( Miyakita, Y; Momota, H; Narita, Y; Shibui, S, 2013) |
| "We present a case of a 12-year-old female with a germline TP53 mutation who presented with anaplastic astrocytoma and subsequent acute lymphoblastic leukemia (ALL) 13 months after starting treatment with temozolomide (TMZ)." | 7.76 | Acute lymphoblastic leukemia after temozolomide treatment for anaplastic astrocytoma in a child with a germline TP53 mutation. ( Hosono, A; Makimoto, A; Miyakita, Y; Momota, H; Nariata, Y; Narita, Y; Shibui, S, 2010) |
| "Case report of a 77-year-old woman with a radiation-induced, high-grade cerebellar glioma that responded durably to temozolomide." | 7.74 | Durable response of a radiation-induced, high-grade cerebellar glioma to temozolomide. ( Doherty, LM; Drappatz, J; Kesari, S; Monje, ML; Ramakrishna, NR; Wen, PY; Young, G, 2007) |
| "Children and young adults with recurrent or treatment-induced malignant gliomas have limited responses to temozolomide or oral VP-16 when either is administered as a single agent." | 7.73 | Temozolomide and oral VP-16 for children and young adults with recurrent or treatment-induced malignant gliomas. ( Bouffet, E; Foreman, N; Korones, DN; Smith, A, 2006) |
| "Patients with grade IV astrocytoma or glioblastoma multiforme (GBM) have a median survival of <12 months, increased to 14." | 5.43 | Regression of a glioblastoma multiforme: spontaneous versus a potential antineoplastic effect of dexamethasone and levetiracetam. ( Ajit, NE; Burton, GV; El-Osta, H; Peddi, P, 2016) |
| "The alkylating agent temozolomide (TMZ) is widely used for the treatment of gliomas." | 5.17 | Secondary hematological malignancies associated with temozolomide in patients with glioma. ( Miyakita, Y; Momota, H; Narita, Y; Shibui, S, 2013) |
| "The therapeutic options for metastatic pheochromocytomas/paragangliomas (mPPGLs) include chemotherapy with cyclophosphamide/vincristine/dacarbazine (CVD), temozolomide monotherapy, radionuclide therapies, and tyrosine kinase inhibitors such as sunitinib." | 4.31 | Responses to systemic therapy in metastatic pheochromocytoma/paraganglioma: a retrospective multicenter cohort study. ( Auernhammer, CJ; Bechmann, N; Beuschlein, F; Bornstein, SR; Dischinger, U; Fischer, A; Fliedner, SMJ; Grossman, AB; Hantel, C; Kloos, S; Kroiss, M; Maurer, J; Mohr, H; Nölting, S; Pacak, K; Pamporaki, C; Pellegata, NS; Reincke, M; Remde, H; Reul, A; Robledo, M; Timmers, HJLM; Wang, K, 2023) |
| "We present a case of a 12-year-old female with a germline TP53 mutation who presented with anaplastic astrocytoma and subsequent acute lymphoblastic leukemia (ALL) 13 months after starting treatment with temozolomide (TMZ)." | 3.76 | Acute lymphoblastic leukemia after temozolomide treatment for anaplastic astrocytoma in a child with a germline TP53 mutation. ( Hosono, A; Makimoto, A; Miyakita, Y; Momota, H; Nariata, Y; Narita, Y; Shibui, S, 2010) |
| "Temozolomide (TMZ) is an oral alkylating agent with significant activity against glioblastoma multiforme (GBM) and melanoma." | 3.75 | Non-Hodgkin lymphoma following temozolomide. ( Das, P; Dwary, A; Goyal, S; Gupta, D; Mohanti, BK; Muzumder, S; Sharma, A; Thulkar, S, 2009) |
| "Case report of a 77-year-old woman with a radiation-induced, high-grade cerebellar glioma that responded durably to temozolomide." | 3.74 | Durable response of a radiation-induced, high-grade cerebellar glioma to temozolomide. ( Doherty, LM; Drappatz, J; Kesari, S; Monje, ML; Ramakrishna, NR; Wen, PY; Young, G, 2007) |
| "Children and young adults with recurrent or treatment-induced malignant gliomas have limited responses to temozolomide or oral VP-16 when either is administered as a single agent." | 3.73 | Temozolomide and oral VP-16 for children and young adults with recurrent or treatment-induced malignant gliomas. ( Bouffet, E; Foreman, N; Korones, DN; Smith, A, 2006) |
| "Glioblastoma multiforme is the most common and most lethal pri- mary malignant tumor of the central nervous system." | 2.50 | Astrocytoma malignum in glioblastoma multiforme vertens with long term survival--case report and a literature review. ( Bochenek-Cibor, J; Krupa, M; Moskała, M; Trojanowski, T, 2014) |
| " Alternative dosing regimens, such as 1-week on/1-week off, or 3-week on/1-week off, that deliver more prolonged exposure have been observed to result in higher cumulative doses than the standard 5-day regimen and may deplete tumor-derived O6-methylguanine-DNA methyltransferase (MGMT) in tumor cells, thus sensitizing tumor cells to the effects of TMZ." | 2.45 | [Treatment of glioma with temozolomide]. ( Nishikawa, R, 2009) |
| "Patients with grade IV astrocytoma or glioblastoma multiforme (GBM) have a median survival of <12 months, increased to 14." | 1.43 | Regression of a glioblastoma multiforme: spontaneous versus a potential antineoplastic effect of dexamethasone and levetiracetam. ( Ajit, NE; Burton, GV; El-Osta, H; Peddi, P, 2016) |
| "Histological examination revealed anaplastic astrocytoma." | 1.38 | Radiation-induced spinal cord anaplastic astrocytoma subsequent to radiotherapy for testicular seminoma. ( Hoshimaru, M; Kawanabe, Y; Kihara, S; Koizumi, T; Sasaki, N; Sawada, M; Ueda, S; Yukawa, H, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 8 (34.78) | 29.6817 |
| 2010's | 11 (47.83) | 24.3611 |
| 2020's | 4 (17.39) | 2.80 |
| Authors | Studies |
|---|---|
| Urquhart, C | 3 |
| Fleming, B | 3 |
| Harper, I | 3 |
| Aloj, L | 3 |
| Armstrong, R | 3 |
| Hook, L | 3 |
| Long, AM | 3 |
| Jackson, C | 3 |
| Gallagher, FA | 3 |
| McLean, MA | 3 |
| Tarpey, P | 3 |
| Kosmoliaptsis, V | 3 |
| Nicholson, J | 3 |
| Hendriks, AEJ | 3 |
| Casey, RT | 3 |
| Fischer, A | 1 |
| Kloos, S | 1 |
| Remde, H | 1 |
| Dischinger, U | 1 |
| Pamporaki, C | 1 |
| Timmers, HJLM | 1 |
| Robledo, M | 1 |
| Fliedner, SMJ | 1 |
| Wang, K | 1 |
| Maurer, J | 1 |
| Reul, A | 1 |
| Bechmann, N | 1 |
| Hantel, C | 1 |
| Mohr, H | 1 |
| Pellegata, NS | 1 |
| Bornstein, SR | 1 |
| Kroiss, M | 1 |
| Auernhammer, CJ | 1 |
| Reincke, M | 1 |
| Pacak, K | 1 |
| Grossman, AB | 1 |
| Beuschlein, F | 1 |
| Nölting, S | 1 |
| Kiang, KM | 1 |
| Chan, AA | 1 |
| Leung, GK | 1 |
| Renaud, L | 1 |
| Bossard, JB | 1 |
| Carpentier, B | 1 |
| Terriou, L | 1 |
| Cambier, N | 1 |
| Chanteau, G | 1 |
| Escure, G | 1 |
| Tilmont, R | 1 |
| Barbieux, S | 1 |
| Wemeau, M | 1 |
| Hieulle, J | 1 |
| Boyle, EM | 1 |
| Morschhauser, F | 1 |
| Joseph, R | 1 |
| McRee, AJ | 1 |
| Mathews, S | 1 |
| Zeidner, JF | 1 |
| Momota, H | 2 |
| Narita, Y | 2 |
| Miyakita, Y | 2 |
| Shibui, S | 2 |
| Bochenek-Cibor, J | 1 |
| Krupa, M | 1 |
| Moskała, M | 1 |
| Trojanowski, T | 1 |
| Peddi, P | 1 |
| Ajit, NE | 1 |
| Burton, GV | 1 |
| El-Osta, H | 1 |
| Neyns, B | 1 |
| Cordera, S | 1 |
| Joosens, E | 1 |
| Pouratian, N | 1 |
| Nader, P | 1 |
| Weiss, B | 1 |
| Geiger, H | 1 |
| Davies, SM | 1 |
| Sharma, A | 1 |
| Gupta, D | 1 |
| Mohanti, BK | 1 |
| Thulkar, S | 1 |
| Dwary, A | 1 |
| Goyal, S | 1 |
| Muzumder, S | 1 |
| Das, P | 1 |
| Nishikawa, R | 1 |
| Nariata, Y | 1 |
| Hosono, A | 1 |
| Makimoto, A | 1 |
| Komatsu, F | 1 |
| Kawaguchi, H | 1 |
| Tsugu, H | 1 |
| Oshiro, S | 1 |
| Komatsu, M | 1 |
| Fukushima, T | 1 |
| Nabeshima, K | 1 |
| Inoue, T | 1 |
| Ogura, M | 1 |
| Todo, T | 1 |
| Tanaka, M | 1 |
| Nannya, Y | 1 |
| Ichikawa, M | 1 |
| Nakamura, F | 1 |
| Kurokawa, M | 1 |
| Kawanabe, Y | 1 |
| Sawada, M | 1 |
| Yukawa, H | 1 |
| Ueda, S | 1 |
| Sasaki, N | 1 |
| Koizumi, T | 1 |
| Kihara, S | 1 |
| Hoshimaru, M | 1 |
| Vajtai, I | 1 |
| Vassella, E | 1 |
| Hewer, E | 1 |
| Kappeler, A | 1 |
| Reinert, MM | 1 |
| Khoo, HM | 1 |
| Kishima, H | 1 |
| Kinoshita, M | 1 |
| Goto, Y | 1 |
| Kagawa, N | 1 |
| Hashimoto, N | 1 |
| Maruno, M | 1 |
| Yoshimine, T | 1 |
| Dixit, S | 1 |
| Salvage, D | 1 |
| Rajaraman, C | 1 |
| Hingorani, M | 1 |
| Rowland-Hill, C | 1 |
| Korones, DN | 1 |
| Smith, A | 1 |
| Foreman, N | 1 |
| Bouffet, E | 2 |
| Noronha, V | 1 |
| Berliner, N | 1 |
| Ballen, KK | 1 |
| Lacy, J | 1 |
| Kracher, J | 1 |
| Baehring, J | 1 |
| Henson, JW | 1 |
| Monje, ML | 1 |
| Ramakrishna, NR | 1 |
| Young, G | 1 |
| Drappatz, J | 1 |
| Doherty, LM | 1 |
| Wen, PY | 1 |
| Kesari, S | 1 |
| Terasaki, M | 1 |
| Katsuki, H | 1 |
| Fukushima, S | 1 |
| Shigemori, M | 1 |
5 reviews available for temozolomide and Cancer, Second Primary
| Article | Year |
|---|---|
The use of temozolomide in paediatric metastatic phaeochromocytoma/paraganglioma: A case report and literature review.
Topics: Adrenal Gland Neoplasms; Adult; Brain Neoplasms; Child; Female; Humans; Neoplasms, Second Primary; P | 2022 |
The use of temozolomide in paediatric metastatic phaeochromocytoma/paraganglioma: A case report and literature review.
Topics: Adrenal Gland Neoplasms; Adult; Brain Neoplasms; Child; Female; Humans; Neoplasms, Second Primary; P | 2022 |
The use of temozolomide in paediatric metastatic phaeochromocytoma/paraganglioma: A case report and literature review.
Topics: Adrenal Gland Neoplasms; Adult; Brain Neoplasms; Child; Female; Humans; Neoplasms, Second Primary; P | 2022 |
The use of temozolomide in paediatric metastatic phaeochromocytoma/paraganglioma: A case report and literature review.
Topics: Adrenal Gland Neoplasms; Adult; Brain Neoplasms; Child; Female; Humans; Neoplasms, Second Primary; P | 2022 |
Astrocytoma malignum in glioblastoma multiforme vertens with long term survival--case report and a literature review.
Topics: Adult; Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neoplasms; Chemoradiotherapy, Adjuvant; | 2014 |
[Treatment of glioma with temozolomide].
Topics: Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Pro | 2009 |
Temozolomide may induce therapy-related acute lymphoblastic leukaemia.
Topics: Antineoplastic Agents, Alkylating; Dacarbazine; Glioma; Humans; Neoplasms, Second Primary; Precursor | 2011 |
Treatment-related myelodysplasia/AML in a patient with a history of breast cancer and an oligodendroglioma treated with temozolomide: case study and review of the literature.
Topics: Aged; Breast Neoplasms; Dacarbazine; Female; Humans; Leukemia, Myeloid, Acute; Myelodysplastic Syndr | 2006 |
2 trials available for temozolomide and Cancer, Second Primary
| Article | Year |
|---|---|
Secondary hematological malignancies associated with temozolomide in patients with glioma.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chil | 2013 |
Pilot trial of the rate of response, safety, and tolerability of temozolomide and oral VP-16 in patients with recurrent or treatment-induced malignant central nervous system tumors.
Topics: Administration, Oral; Adolescent; Adult; Aged; Antineoplastic Agents; Brain Neoplasms; Dacarbazine; | 2008 |
16 other studies available for temozolomide and Cancer, Second Primary
| Article | Year |
|---|---|
Responses to systemic therapy in metastatic pheochromocytoma/paraganglioma: a retrospective multicenter cohort study.
Topics: Adrenal Gland Neoplasms; Brain Neoplasms; Cardiovascular Diseases; Cohort Studies; Humans; Iodine Ra | 2023 |
Secondary gliosarcoma: the clinicopathological features and the development of a patient-derived xenograft model of gliosarcoma.
Topics: Animals; Biomarkers, Tumor; Brain; Brain Neoplasms; Cell Cycle Proteins; Chemoradiotherapy; Cranioto | 2021 |
Treatment with temozolomide and ibrutinib in recurrent/refractory primary (PCNSL) and secondary CNS lymphoma (SCNSL).
Topics: Adenine; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Central Ner | 2021 |
Inversion 16 (inv(16)) acute myeloid leukemia (AML) following treatment with radiation, capecitabine, and temozolomide in a patient with metastatic neuroendocrine tumor (NET).
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemoradiotherapy; Chromosome I | 2019 |
Regression of a glioblastoma multiforme: spontaneous versus a potential antineoplastic effect of dexamethasone and levetiracetam.
Topics: Antineoplastic Combined Chemotherapy Protocols; Astrocytoma; Brain Neoplasms; Cognition Disorders; D | 2016 |
Non-Hodgkin's lymphoma in patients with glioma treated with temozolomide.
Topics: Animals; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Dacarbaz | 2008 |
Possible leukemogenic potential of temozolomide.
Topics: Animals; Antineoplastic Agents, Alkylating; Bone Marrow Cells; Dacarbazine; DNA; Mice; Mice, Transge | 2009 |
Non-Hodgkin lymphoma following temozolomide.
Topics: Adult; Antineoplastic Agents, Alkylating; Dacarbazine; Female; Glioblastoma; Humans; Lymphoma, Non-H | 2009 |
Acute lymphoblastic leukemia after temozolomide treatment for anaplastic astrocytoma in a child with a germline TP53 mutation.
Topics: Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neoplasms; Child; Dacarbazine; Female; Frontal | 2010 |
Radiation-induced astrocytoma with rapid malignant transformation: case report.
Topics: Antineoplastic Agents, Alkylating; Astrocytoma; Basal Ganglia; Brain Neoplasms; Cell Transformation, | 2011 |
Radiation-induced spinal cord anaplastic astrocytoma subsequent to radiotherapy for testicular seminoma.
Topics: Antineoplastic Agents; Astrocytoma; Chemotherapy, Adjuvant; Combined Modality Therapy; Dacarbazine; | 2012 |
Sarcomatous evolution of oligodendroglioma ("oligosarcoma"): confirmatory report of an uncommon pattern of malignant progression in oligodendroglial tumors.
Topics: Adult; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chromosome Deletion; Chromosomes, Human, | 2012 |
Radiation-induced anaplastic ependymoma with a remarkable clinical response to temozolomide: a case report.
Topics: Adult; Antineoplastic Agents, Alkylating; Astrocytoma; Cerebellar Neoplasms; Dacarbazine; Ependymoma | 2013 |
Hypernatremia-associated myelinolysis following the management of sepsis in a patient with glioblastoma treated with radiotherapy and temozolomide.
Topics: Antineoplastic Agents; Brain Diseases; Brain Neoplasms; Carcinoma; Carcinoma, Papillary; Dacarbazine | 2013 |
Temozolomide and oral VP-16 for children and young adults with recurrent or treatment-induced malignant gliomas.
Topics: Administration, Oral; Adolescent; Adult; Antineoplastic Agents, Alkylating; Antineoplastic Agents, P | 2006 |
Durable response of a radiation-induced, high-grade cerebellar glioma to temozolomide.
Topics: Aged; Antineoplastic Agents, Alkylating; Carcinoma, Squamous Cell; Cerebellar Neoplasms; Dacarbazine | 2007 |