Page last updated: 2024-11-04

temozolomide and Brain Neoplasms

temozolomide has been researched along with Brain Neoplasms in 3270 studies

Brain Neoplasms: Neoplasms of the intracranial components of the central nervous system, including the cerebral hemispheres, basal ganglia, hypothalamus, thalamus, brain stem, and cerebellum. Brain neoplasms are subdivided into primary (originating from brain tissue) and secondary (i.e., metastatic) forms. Primary neoplasms are subdivided into benign and malignant forms. In general, brain tumors may also be classified by age of onset, histologic type, or presenting location in the brain.

Research Excerpts

ExcerptRelevanceReference
"Addition of temozolomide (TMZ) to radiotherapy (RT) improves overall survival (OS) in patients with glioblastoma (GBM), but previous studies suggest that patients with tumors harboring an unmethylated MGMT promoter derive minimal benefit."9.69Radiotherapy combined with nivolumab or temozolomide for newly diagnosed glioblastoma with unmethylated MGMT promoter: An international randomized phase III trial. ( Baehring, J; Bähr, O; Brandes, AA; Butowski, N; Carpentier, AF; Chalamandaris, AG; Cloughesy, T; Di Giacomo, AM; Fu, AZ; Idbaih, A; Khasraw, M; Lassen, U; Lim, M; Liu, Y; Lombardi, G; Mulholland, P; Muragaki, Y; Omuro, A; Potter, V; Qian, X; Reardon, DA; Roth, P; Sepulveda, JM; Sumrall, A; Tabatabai, G; Tatsuoka, K; van den Bent, M; Vauleon, E; Weller, M, 2023)
"Despite intensive treatment with surgery, radiation therapy, temozolomide (TMZ) chemotherapy, and tumor-treating fields, mortality of newly diagnosed glioblastoma (nGBM) remains very high."9.69Phase IIa Study of SurVaxM Plus Adjuvant Temozolomide for Newly Diagnosed Glioblastoma. ( Abad, AP; Ahluwalia, MS; Belal, AN; Birkemeier, MT; Casucci, DM; Ciesielski, MJ; Curry, WT; Dharma, SS; Dhawan, A; Fenstermaker, RA; Figel, SA; Hutson, AD; Liu, S; Mechtler, LL; Mogensen, KM; Peereboom, DM; Qiu, J; Reardon, DA; Withers, HG; Wong, ET, 2023)
"Preclinical data showed that prophylactic, low-dose temozolomide (TMZ) significantly prevented breast cancer brain metastasis."9.69Phase I Study and Cell-Free DNA Analysis of T-DM1 and Metronomic Temozolomide for Secondary Prevention of HER2-Positive Breast Cancer Brain Metastases. ( Anders, CK; Arisa, O; Armstrong, TS; Brastianos, P; Burton, E; Carter, S; Connolly, RM; Figg, WD; Gilbert, MR; Houston, N; Jenkins, S; Khan, I; Lipkowitz, S; Mendoza, TR; Mozarsky, B; Nousome, D; Peer, CJ; Shah, R; Smart, DD; Smith, KL; Steeg, PS; Steinberg, SM; Tweed, C; Vera, E; Wu, X; Zhang, W; Zimmer, AS, 2023)
"Despite standard treatments including chemoradiotherapy with temozolomide (TMZ) (STUPP protocol), the prognosis of glioblastoma patients remains poor."9.69Phase I/II study testing the combination of AGuIX nanoparticles with radiochemotherapy and concomitant temozolomide in patients with newly diagnosed glioblastoma (NANO-GBM trial protocol). ( Biau, J; Casile, M; De Beaumont, O; Dufort, S; Durando, X; Le Duc, G; Loeffler, M; Molnar, I; Moreau, J; Seddik, K; Thivat, E, 2023)
"This study was aimed at analyzing the efficacy and safety of an injectable form of chlorogenic acid (CGA) in patients with recurrent high-grade glioma after standard of care treatments, through a first-in-human, open-label, dose-escalation phase I trial."9.69Phase I study of chlorogenic acid injection for recurrent high-grade glioma with long-term follow-up. ( Chen, F; Deng, J; Jiang, J; Kang, X; Kang, Z; Li, S; Li, W; Yang, H; Zhang, J, 2023)
"In an international randomised controlled phase II study of temozolomide (TMZ) versus TMZ in combination with bevacizumab (BEV) in locally diagnosed non-1p/19q co-deleted World Health Organization grade 2 or 3 gliomas with a first and contrast-enhancing recurrence after initial radiotherapy, and overall survival at 12 months was not significantly different (61% in the TMZ arm and 55% in the TMZ + BEV arm)."9.69Health-related quality-of-life results from the randomised phase II TAVAREC trial on temozolomide with or without bevacizumab in 1p/19q intact first-recurrence World Health Organization grade 2 and 3 glioma (European Organization for Research and Treatmen ( Bottomley, A; Clement, PM; Coens, C; de Vos, FYF; Ghislain, I; Golfinopoulos, V; Idbaih, A; Klein, M; Lewis, J; Machingura, A; Mulholland, PJ; Reijneveld, JC; Taal, W; Taphoorn, MJB; van den Bent, MJ; Wick, W, 2023)
"In a post hoc analysis of the CATNON trial (NCT00626990), we explored whether adding temozolomide to radiotherapy improves outcome in patients with IDH1/2 wildtype (wt) anaplastic astrocytomas with molecular features of glioblastoma [redesignated as glioblastoma, isocitrate dehydrogenase-wildtype (IDH-wt) in the 2021 World Health Organization (WHO) classification of central nervous system tumors]."9.51Temozolomide and Radiotherapy versus Radiotherapy Alone in Patients with Glioblastoma, IDH-wildtype: Post Hoc Analysis of the EORTC Randomized Phase III CATNON Trial. ( Aldape, K; Atmodimedjo, PN; Baumert, BG; Baurain, JF; Brandes, AA; Brouwer, RWW; Cheung, KJ; Chinot, OL; Clement, PM; de Heer, I; Dubbink, HJ; Erridge, SC; French, PJ; Gill, S; Golfinopoulos, V; Gorlia, T; Griffin, M; Hoogstrate, Y; Jenkins, RB; Kros, JM; Mason, WP; McBain, C; Nowak, AK; Rogers, L; Rudà, R; Sanson, M; Taal, W; Tesileanu, CMS; van den Bent, MJ; van IJcken, WFJ; van Linde, ME; Vogelbaum, MA; von Deimling, A; Weller, M; Wesseling, P; Wheeler, H; Wick, W, 2022)
"Temozolomide is applied as the standard chemotherapy agent in patients with glioblastoma (GBM) after surgery."9.51The efficacy of temozolomide combined with levetiracetam for glioblastoma (GBM) after surgery: a study protocol for a double-blinded and randomized controlled trial. ( Cheng, Y; Huang, N; Liu, G; Mao, J; Sun, M; Tao, Y; Wen, R; Xie, Z; Zhang, X; Zhao, G, 2022)
"Nearly all patients with newly diagnosed glioblastoma experience recurrence following standard-of-care radiotherapy (RT) + temozolomide (TMZ)."9.51Phase III trial of chemoradiotherapy with temozolomide plus nivolumab or placebo for newly diagnosed glioblastoma with methylated MGMT promoter. ( Ansstas, G; Baehring, J; De Vos, F; Finocchiaro, G; Honnorat, J; Idbaih, A; Kinoshita, M; Lee, M; Leung, D; Lim, M; Mellinghoff, IK; Omuro, A; Petrecca, K; Raval, RR; Reardon, DA; Roberts, M; Sahebjam, S; Slepetis, R; Steinbach, J; Sumrall, A; Taylor, JW; Warad, D; Weller, M; Wick, A, 2022)
"The KNOG-1101 study showed improved 2-year PFS with temozolomide during and after radiotherapy compared to radiotherapy alone for patients with anaplastic gliomas."9.51Influence of Concurrent and Adjuvant Temozolomide on Health-Related Quality of Life of Patients with Grade III Gliomas: A Secondary Analysis of a Randomized Clinical Trial (KNOG-1101 Study). ( Ahn, GS; Chang, JH; Choe, G; Choi, BS; Hong, YK; Hwang, K; Joo, J; Jung, TY; Kang, SG; Kim, CY; Kim, EY; Kim, JH; Kim, SH; Kim, TM; Kim, YJ; Lee, DE; Nam, DH; Park, CK; Yoo, H, 2022)
"Patients age 18 or older with histologically proven and progressive ependymoma or anaplastic ependymoma were eligible and received dose-dense TMZ and daily lapatinib."9.41A phase II study of dose-dense temozolomide and lapatinib for recurrent low-grade and anaplastic supratentorial, infratentorial, and spinal cord ependymoma. ( Aldape, K; Armstrong, TS; Gerstner, ER; Gilbert, MR; Lieberman, F; Mendoza, T; Mikkelsen, T; Omuro, A; Robins, HI; Vera, E; Wen, PY; Wu, J; Yuan, Y, 2021)
" We performed a phase I study to determine the maximum tolerated dose and preliminary efficacy of pegylated nanoliposomal irinotecan (nal-IRI)+metronomic temozolomide (TMZ) in patients with recurrent glioblastoma."9.41Nanoliposomal Irinotecan and Metronomic Temozolomide for Patients With Recurrent Glioblastoma: BrUOG329, A Phase I Brown University Oncology Research Group Trial. ( Baekey, J; Carcieri, A; Cielo, D; Disano, D; Donnelly, J; Elinzano, H; MacKinnon, K; Mohler, A; Robison, J; Safran, H; Sturtevant, A; Toms, S; Vatketich, J; Wood, R, 2021)
"To investigate the toxicity profile and establish an optimal dosing schedule of zotiraciclib with temozolomide in patients with recurrent high-grade astrocytoma."9.41Phase I Study of Zotiraciclib in Combination with Temozolomide for Patients with Recurrent High-grade Astrocytomas. ( Aboud, O; Ahmad, S; Antony, R; Armstrong, TS; Boris, L; Bryla, C; Burton, EM; Butler, MK; Calvo, KR; Cordova, C; Figg, WD; Fink, D; Gallin, JI; Garren, N; Gilbert, MR; Gonzales, J; Grajkowska, E; Kuhns, DB; Leeper, H; Lindsley, M; Lollo, N; Long Priel, DA; Mendoza, TR; Mentges, K; Pang, Y; Peer, CJ; Penas-Prado, M; Siegel, C; Sissung, TM; Su, YT; Theeler, BJ; Vera, E; Wu, J; Yu, G; Yuan, Y, 2021)
"Temozolomide offers minimal benefit in patients with glioblastoma with unmethylated O6-methylguanine-DNA methyltransferase (MGMT) promoter status, hence, the need for novel therapies."9.41A randomized phase II trial of veliparib, radiotherapy, and temozolomide in patients with unmethylated MGMT glioblastoma: the VERTU study. ( Ashley, DM; Back, M; Barnes, EH; Buckland, ME; Fisher, L; Foote, MC; Hall, M; Khasraw, M; Koh, ES; Leonard, R; Lwin, Z; McDonald, KL; Rosenthal, M; Sim, HW; Simes, J; Sulman, EP; Wheeler, H; Yip, S, 2021)
"CINV remains a distressing side effect experienced by glioma patients receiving multi-day temozolomide therapy, in spite of guideline-based antiemetic therapy with selective serotonin-receptor-antagonists."9.34Randomized open-label phase II trial of 5-day aprepitant plus ondansetron compared to ondansetron alone in the prevention of chemotherapy-induced nausea-vomiting (CINV) in glioma patients receiving adjuvant temozolomide. ( Affronti, ML; Desjardins, A; Friedman, HS; Healy, P; Herndon, JE; Lipp, ES; McSherry, F; Miller, E; Patel, MP; Peters, KB; Randazzo, DM; Woodring, S, 2020)
" We investigated Depatux-M in combination with temozolomide or as a single agent in a randomized controlled phase II trial in recurrent EGFR amplified glioblastoma."9.34INTELLANCE 2/EORTC 1410 randomized phase II study of Depatux-M alone and with temozolomide vs temozolomide or lomustine in recurrent EGFR amplified glioblastoma. ( Ansell, P; Brilhante, J; Chinot, O; Clement, PM; Coens, C; De Vos, F; Dey, J; Dubbink, HJ; Eoli, M; Franceschi, E; French, P; Frenel, JS; Golfinopoulos, V; Gorlia, T; Krause, S; Looman, J; Nuyens, S; Sanghera, P; Sepulveda, JM; Smits, M; Spruyt, M; Van Den Bent, M; Walenkamp, A; Weller, M; Whenham, N, 2020)
"We sought to determine the maximum tolerated dose (MTD) of 5-fraction stereotactic radiosurgery (SRS) with 5-mm margins delivered with concurrent temozolomide in newly diagnosed glioblastoma (GBM)."9.34A phase I/II trial of 5-fraction stereotactic radiosurgery with 5-mm margins with concurrent temozolomide in newly diagnosed glioblastoma: primary outcomes. ( Adler, JR; Azoulay, M; Chang, SD; Choi, CYH; Fujimoto, D; Gibbs, IC; Hancock, SL; Harraher, C; Harsh, GR; Hayden Gephart, M; Jacobs, LR; Li, G; Modlin, LA; Nagpal, S; Pollom, EL; Recht, LD; Seiger, K; Soltys, SG; Thomas, RP; Usoz, M; von Eyben, R; Wynne, J, 2020)
"A Pediatric Brain Tumor Consortium (PBTC) phase I/II trial of veliparib and radiation followed by veliparib and temozolomide (TMZ) was conducted in children with newly diagnosed diffuse intrinsic pontine glioma (DIPG)."9.34A phase I/II study of veliparib (ABT-888) with radiation and temozolomide in newly diagnosed diffuse pontine glioma: a Pediatric Brain Tumor Consortium study. ( Adesina, A; Ansell, P; Baxter, PA; Billups, CA; Blaney, SM; Broniscer, A; Dunkel, IJ; Fouladi, M; Giranda, V; Kilburn, L; Li, XN; Onar-Thomas, A; Paulino, A; Poussaint, TY; Quaddoumi, I; Smith, ER; Su, JM; Thompson, P, 2020)
" TTFields plus Temozolomide (TTFields/TMZ) extended survival versus TMZ alone in newly diagnosed glioblastoma (GBM) patients in the EF-14 trial."9.34Tumor treating fields plus temozolomide for newly diagnosed glioblastoma: a sub-group analysis of Korean patients in the EF-14 phase 3 trial. ( Chang, JH; Hong, YK; Kim, CY; Kim, JH; Kim, OL; Kim, SH; Nam, DH; Paek, SH, 2020)
"Ipi-Glio is a phase II, open label, randomised study of ipilimumab with temozolomide (Arm A) versus temozolomide alone (Arm B) after surgery and chemoradiotherapy in patients with recently diagnosed glioblastoma."9.34A phase II open label, randomised study of ipilimumab with temozolomide versus temozolomide alone after surgery and chemoradiotherapy in patients with recently diagnosed glioblastoma: the Ipi-Glio trial protocol. ( Blagden, S; Brooks, C; Brown, NF; Coutts, T; Elhussein, L; Holmes, J; Hoskin, P; Maughan, T; Mulholland, P; Ng, SM; Roberts, C, 2020)
"Standard of care for glioblastoma includes concurrent chemoradiation and maintenance temozolomide with tumor treatment fields (TTFields)."9.34Initial experience with scalp sparing radiation with concurrent temozolomide and tumor treatment fields (SPARE) for patients with newly diagnosed glioblastoma. ( Andrews, DW; Bar-Ad, V; Chervoneva, I; Evans, JJ; Farrell, CJ; Glass, J; Judy, K; Liu, H; Ly, M; Martinez, N; Palmer, JD; Shi, W; Song, A; Werner-Wasik, M, 2020)
"Temozolomide (TMZ) has been the standard-of-care chemotherapy for glioblastoma (GBM) patients for more than a decade."9.34Image-based metric of invasiveness predicts response to adjuvant temozolomide for primary glioblastoma. ( Bendok, BR; Doyle, T; Hawkins-Daarud, A; Hu, LS; Jackson, PR; Johnston, SK; Massey, SC; Mrugala, MM; Porter, AB; Sarkaria, JN; Singleton, KW; Swanson, KR; Vora, S; White, H; Whitmire, P, 2020)
"To report the long-term outcomes of the RTOG 0424 study of a high-risk, low-grade glioma population treated with concurrent and adjuvant temozolomide (TMZ) and radiation therapy (RT)."9.34Phase 2 Study of a Temozolomide-Based Chemoradiation Therapy Regimen for High-Risk, Low-Grade Gliomas: Long-Term Results of Radiation Therapy Oncology Group 0424. ( Bahary, JP; Barani, IJ; Bovi, JA; Chakravatri, A; D'Souza, D; Doyle, T; Fisher, BJ; Fiveash, JB; Fox, S; Howard, SP; Kwok, Y; Laack, NN; Lesser, GJ; Macdonald, DR; Mehta, MP; Michael Yu, HH; Pugh, SL; Rogers, CL; Strasser, JF; Wahl, DR; Werner-Wasik, M; Won, M, 2020)
"Standard treatment for glioblastoma is radiation with concomitant and adjuvant temozolomide for 6 cycles, although the optimal number of cycles of adjuvant temozolomide has long been a subject of debate."9.34A phase II randomized, multicenter, open-label trial of continuing adjuvant temozolomide beyond 6 cycles in patients with glioblastoma (GEINO 14-01). ( Alonso, M; Balana, C; Berrocal, A; Carrato, C; Covela, M; de Las Peñas, R; Del Barco, S; Domenech, M; Esteve, A; Estival, A; Fuster, J; Gallego, O; Gil-Gil, M; Gironés, R; Herrero, A; Luque, R; Manuel Sepúlveda, J; Martinez-García, M; Mesia, C; Munne, N; Muñoz-Langa, J; Navarro, LM; Olier, C; Peralta, S; Perez-Martín, FJ; Perez-Segura, P; Pineda, E; Sanz, C; Vaz, MA; Villa, S, 2020)
"This study aimed to explore the genetic alterations and to identify good responders in the experimental arm in the tumor samples from newly diagnosed glioblastoma (GBM) patients enrolled in JCOG0911; a randomized phase II trial was conducted to compare the efficacy of interferonβ (IFNβ) plus temozolomide (TMZ) with that of TMZ alone."9.34Genetic analysis in patients with newly diagnosed glioblastomas treated with interferon-beta plus temozolomide in comparison with temozolomide alone. ( Abe, T; Adilijiang, A; Aoki, K; Aoki, T; Arakawa, Y; Asai, A; Asano, K; Beppu, T; Hashimoto, N; Hirano, H; Hirano, M; Ishikawa, E; Ito, T; Iwadate, Y; Kayama, T; Kobayashi, H; Kumabe, T; Kurisu, K; Maeda, S; Maruyama, T; Matsumura, A; Matsuo, T; Mishima, K; Motomura, K; Mukasa, A; Muragaki, Y; Nagane, M; Nakamura, H; Nakasu, Y; Narita, Y; Natsume, A; Nishikawa, R; Ohka, F; Okuno, Y; Onishi, T; Sasaki, H; Sato, S; Shibui, S; Shinoura, N; Sugiyama, K; Sumi, M; Terasaki, M; Wakabayashi, T; Yamasaki, F; Yoshimoto, K; Yoshino, A, 2020)
" In a previously-published multi-centre randomized clinical trial of 562 elderly glioblastoma patients, temozolomide plus short-course radiotherapy conferred a survival benefit over radiotherapy alone."9.34Temozolomide and seizure outcomes in a randomized clinical trial of elderly glioblastoma patients. ( Brandes, AA; Cairncross, JG; Climans, SA; Ding, K; Fay, M; Laperriere, N; Mason, WP; Menten, J; Nishikawa, R; O'Callaghan, CJ; Perry, JR; Phillips, C; Roa, W; Wick, W; Winch, C, 2020)
"The optimal management of high risk WHO grade II gliomas after surgery is debated including the role of initial temozolomide to delay radiotherapy and risk of cognitive defects."9.30Efficacy of initial temozolomide for high-risk low grade gliomas in a phase II AINO (Italian Association for Neuro-Oncology) study: a post-hoc analysis within molecular subgroups of WHO 2016. ( Bello, L; Bertero, L; Carapella, CM; Caroli, M; Cassoni, P; Dealis, C; Faedi, M; Marchese, G; Migliore, E; Pace, A; Pellerino, A; Rudà, R; Soffietti, R, 2019)
"To determine the efficacy of the thrombopoietin receptor agonist romiplostim for the prevention of temozolomide-induced thrombocytopenia in newly diagnosed glioblastoma."9.30Romiplostim for temozolomide-induced thrombocytopenia in glioblastoma: The PLATUM trial. ( Cartalat, S; Chinot, O; Devos, P; Di Stefano, AL; Dubois, F; Houillier, C; Le Rhun, E; Lepage, C; Reyns, N; Weller, M, 2019)
" The present standard treatment for newly diagnosed glioblastoma is maximal resection followed by chemoradiotherapy with temozolomide."9.30A multicenter randomized phase III study for newly diagnosed maximally resected glioblastoma comparing carmustine wafer implantation followed by chemoradiotherapy with temozolomide with chemoradiotherapy alone; Japan Clinical Oncology Group Study JCOG1703 ( Ichimura, K; Igaki, H; Kadota, T; Katayama, H; Kinoshita, M; Komori, T; Kumabe, T; Mizusawa, J; Narita, Y; Nishikawa, R; Saito, R; Sumi, M, 2019)
" We assessed the efficacy and safety of iniparib with standard radiotherapy and temozolomide in patients with newly diagnosed glioblastoma (GBM)."9.30Phase II Study of Iniparib with Concurrent Chemoradiation in Patients with Newly Diagnosed Glioblastoma. ( Ahluwalia, MS; Blakeley, JO; Chi, AS; Desideri, S; Eichler, A; Grossman, SA; Mikkelsen, T; Nabors, LB; Ribas, IG; Rosenfeld, MR; Ye, X, 2019)
"Memantine, mefloquine, and metformin can be combined safely with TMZ in patients with newly diagnosed glioblastoma."9.30Phase 1 lead-in to a phase 2 factorial study of temozolomide plus memantine, mefloquine, and metformin as postradiation adjuvant therapy for newly diagnosed glioblastoma. ( Aldape, KD; Alfred Yung, WK; Conrad, CA; de Groot, JF; Gilbert, MR; Groves, MD; Hess, KR; Loghin, ME; Mammoser, AG; Maraka, S; Melguizo-Gavilanes, I; O'Brien, BJ; Penas-Prado, M; Puduvalli, VK; Sulman, EP; Tremont-Lukats, IW, 2019)
" Gliomas, which are common in dogs and also represent the majority of fatal brain tumours in humans, can be amenable to chemotherapy with temozolomide."9.30Intratumoral temozolomide in spontaneous canine gliomas: feasibility of a novel therapy using implanted microcylinders. ( Hicks, J; Holmes, S; Howerth, E; Kaplan, E; Kaplan, J; Kent, M; Platt, S; Senneca, C; Stewart, G, 2019)
"Preclinical studies have suggested promising activity for the combination of disulfiram and copper (DSF/Cu) against glioblastoma (GBM) including re-sensitization to temozolomide (TMZ)."9.30A multicenter phase II study of temozolomide plus disulfiram and copper for recurrent temozolomide-resistant glioblastoma. ( Boockvar, J; Campian, JL; Chaudhary, R; Chinnaiyan, P; Cohen, AL; Fink, K; Goldlust, S; Huang, J; Marcus, S; Wan, L, 2019)
"The treatment using hypofractionated stereotactic radiotherapy concurrent with temozolomide appeared to be safe and could significantly extend overall survival compared with historical control in complex brain metastases."9.30A Phase II Trial of Concurrent Temozolomide and Hypofractionated Stereotactic Radiotherapy for Complex Brain Metastases. ( Bi, N; Chen, X; Deng, L; Hu, C; Huang, X; Li, J; Li, Y; Liu, F; Liu, Q; Ma, Y; Tian, Y; Wang, K; Wang, W; Xiao, J; Xu, Y; Yang, S; Yi, J; Zhang, H; Zhang, Y; Zhao, R, 2019)
"In RPA V-VI glioblastoma patients both hypofractionated radiotherapy and exclusive temozolomide can be used; the purpose of this trial is to compare these treatment regimens in terms of survival and quality of life."9.30Hypofractionated radiation therapy versus chemotherapy with temozolomide in patients affected by RPA class V and VI glioblastoma: a randomized phase II trial. ( Borghetti, P; Bruni, A; Buglione, M; Fusco, V; Gatta, R; Krengli, M; Magrini, SM; Masini, L; Meduri, B; Pedretti, S; Pegurri, L; Pirtoli, L; Ricardi, U; Riva, N; Santoni, R; Scoccianti, S; Triggiani, L; Turco, E, 2019)
"A multicenter phase II study for assessing the efficacy and the toxicity of hypofractionated radiotherapy with SIB plus temozolomide in patients with glioblastoma was carried out by the Brain Study Group of the Italian Association of Radiation Oncology."9.27Hypofractionated radiotherapy with simultaneous integrated boost (SIB) plus temozolomide in good prognosis patients with glioblastoma: a multicenter phase II study by the Brain Study Group of the Italian Association of Radiation Oncology (AIRO). ( Buglione, M; Detti, B; Doino, D; Fiorentino, A; Fusco, V; Greto, D; Krengli, M; Livi, L; Lonardi, F; Magrini, SM; Marrazzo, L; Marzano, S; Masini, L; Migliaccio, F; Pirtoli, L; Ricardi, U; Rubino, G; Santoni, R; Scoccianti, S, 2018)
"Vorinostat combined with standard chemoradiation had acceptable tolerability in newly diagnosed glioblastoma."9.27Phase I/II trial of vorinostat combined with temozolomide and radiation therapy for newly diagnosed glioblastoma: results of Alliance N0874/ABTC 02. ( Ahluwalia, MS; Anderson, SK; Ballman, KV; Buckner, JC; Cerhan, J; Galanis, E; Gerstner, ER; Giannini, C; Grossman, SA; Jaeckle, K; Lee, EQ; Lesser, GJ; Ligon, KL; Loboda, A; Miller, CR; Moore, DF; Nebozhyn, M; Prados, M; Sarkaria, JN; Schiff, D; Wen, PY, 2018)
"We recently reported an acceptable safety and pharmacokinetic profile of depatuxizumab mafodotin (depatux-m), formerly called ABT-414, plus radiation and temozolomide in newly diagnosed glioblastoma (arm A)."9.27Safety, pharmacokinetics, and antitumor response of depatuxizumab mafodotin as monotherapy or in combination with temozolomide in patients with glioblastoma. ( Ansell, PJ; Butowski, N; Fichtel, L; Fischer, J; Gan, HK; Gomez, EJ; Holen, KD; Kumthekar, P; Lassman, AB; Lee, HJ; Lwin, Z; Mandich, H; Merrell, R; Munasinghe, WP; Reardon, DA; Roberts-Rapp, LA; Scott, AM; van den Bent, M; Wheeler, H; Xiong, H, 2018)
"The GLARIUS trial, which investigated the efficacy of bevacizumab (BEV)/irinotecan (IRI) compared with standard temozolomide in the first-line therapy of O6-methylguanine-DNA methyltransferase (MGMT)-nonmethylated glioblastoma, showed that progression-free survival was significantly prolonged by BEV/IRI, while overall survival was similar in both arms."9.27Quality of life in the GLARIUS trial randomizing bevacizumab/irinotecan versus temozolomide in newly diagnosed, MGMT-nonmethylated glioblastoma. ( Belka, C; Friedrich, F; Glas, M; Goldbrunner, R; Grau, S; Grauer, O; Hänel, M; Hau, P; Herrlinger, U; Kebir, S; Krex, D; Leutgeb, B; Mack, F; Nießen, M; Proescholdt, M; Ringel, F; Rohde, V; Ronellenfitsch, MW; Sabel, M; Schäfer, N; Schaub, C; Schlegel, U; Schnell, O; Steinbach, JP; Stummer, W; Tabatabai, G; Tzaridis, T; Uhl, M; Urbach, H; Vajkoczy, P; Weyerbrock, A, 2018)
"This phase II study was designed to determine the efficacy of the mammalian target of rapamycin (mTOR) inhibitor everolimus administered daily with conventional radiation therapy and chemotherapy in patients with newly diagnosed glioblastoma."9.27A randomized phase II study of everolimus in combination with chemoradiation in newly diagnosed glioblastoma: results of NRG Oncology RTOG 0913. ( Ahluwalia, MS; Ashby, LS; Chinnaiyan, P; Fiveash, JB; Kee, AY; Malone, SC; Mehta, MP; Michael Yu, HH; Mohile, NA; Rojiani, AM; Shih, HA; Stella, PJ; Stieber, VW; Wen, PY; Wendland, MM; Werner-Wasik, M; Won, M, 2018)
" We sought to study vorinostat (VOR), a histone deacetylase inhibitor, in combination with bevacizumab (BEV) and daily metronomic temozolomide (TMZ) in a Phase I/II trial in recurrent high-grade gliomas (HGGs)."9.27Phase I/II trial of vorinostat, bevacizumab, and daily temozolomide for recurrent malignant gliomas. ( Desjardins, A; Friedman, HS; Herndon, JE; Lipp, ES; McSherry, F; Miller, E; Peters, KB; Reardon, DA, 2018)
"Disulfiram has shown promising activity including proteasome inhibitory properties and synergy with temozolomide in preclinical glioblastoma (GBM) models."9.27Final results of a phase I dose-escalation, dose-expansion study of adding disulfiram with or without copper to adjuvant temozolomide for newly diagnosed glioblastoma. ( Ansstas, G; Campian, JL; DeWees, TA; Gujar, AD; Huang, J; Kim, AH; Lockhart, AC; Tran, DD; Tsien, C, 2018)
"Concomitant radiochemotherapy followed by six cycles of temozolomide (= short term) is considered as standard therapy for adults with newly diagnosed glioblastoma."9.27Cost-effectiveness of the long-term use of temozolomide for treating newly diagnosed glioblastoma in Germany. ( Arefian, H; Hartmann, M; Kalff, R; Maschmann, J; Walter, J; Waschke, A, 2018)
"1/CATNON intergroup trial was designed to evaluate the impact on concurrent and adjuvant temozolomide chemotherapy in newly diagnosed non-1p/19q deleted anaplastic gliomas."9.27Radiotherapy quality assurance for the RTOG 0834/EORTC 26053-22054/NCIC CTG CEC.1/CATNON intergroup trial "concurrent and adjuvant temozolomide chemotherapy in newly diagnosed non-1p/19q deleted anaplastic glioma": Individual case review analysis. ( Abrunhosa-Branquinho, AN; Bar-Deroma, R; Baumert, BG; Clementel, E; Collette, S; Feuvret, L; Hurkmans, CW; Liu, Y; Van Beek, K; van den Bent, M; Weber, DC, 2018)
"In this phase II study, we investigate clinical outcomes and tolerability of hypofractionated radiotherapy (HRT) combined with temozolomide (TMZ) to treat elderly patients with glioblastoma (GBM)."9.27Interim Results of a Phase II Study of Hypofractionated Radiotherapy with Concurrent Temozolomide Followed by Adjuvant Temozolomide in Patients over 70 Years Old with Newly Diagnosed Glioblastoma. ( Amsbaugh, M; Boakye, M; Burton, E; Hattab, EM; Nelson, M; Ugiliweneza, B; Williams, B; Woo, S; Yusuf, M, 2018)
"Adult patients with intermediate- to high-grade glioma on adjuvant temozolomide (TMZ) with facilities for live video call were invited to participate in the study."9.27Shadow study: randomized comparison of clinic with video follow-up in glioma undergoing adjuvant temozolomide therapy. ( Chakraborty, S; Chandrasekharan, A; Dsouza, H; Goda, JS; Gupta, T; Jalali, R; Krishnatry, R; M, C; Pande, N; Patil, VM; Tonse, R; Vallathol, DH, 2018)
"In this study, MGMT promoter methylation was an independent prognostic biomarker of high-risk, low-grade glioma treated with temozolomide and radiotherapy."9.27Association of MGMT Promoter Methylation Status With Survival Outcomes in Patients With High-Risk Glioma Treated With Radiotherapy and Temozolomide: An Analysis From the NRG Oncology/RTOG 0424 Trial. ( Aldape, KD; Ashby, LS; Bahary, JP; Becker, AP; Bell, EH; Chakraborty, AR; Chakravarti, A; Fabian, D; Fisher, BJ; Fleming, J; Gray, HJ; Kwok, Y; Laack, NN; Lesser, GJ; Liu, Z; Macdonald, DR; McElroy, JP; Mehta, MP; Robins, HI; Schultz, CJ; Walker, EM; Werner-Wasik, M; Yu, HM; Zhang, P, 2018)
"Mibefradil (MIB), previously approved for treatment of hypertension, is a selective T-type calcium channel blocker with preclinical activity in high-grade gliomas (HGGs)."9.24Timed sequential therapy of the selective T-type calcium channel blocker mibefradil and temozolomide in patients with recurrent high-grade gliomas. ( Desai, AS; Desideri, S; Fisher, JD; Grossman, SA; Holdhoff, M; Leal, J; Lesser, GJ; Lieberman, FS; Lodge, MA; Nabors, LB; Read, WL; Schiff, D; Supko, JG; Wahl, RL; Walbert, T; Ye, X, 2017)
"We report a longitudinal assessment of health-related quality of life (HRQOL) in patients with glioblastoma (GBM) treated on a prospective dose escalation trial of 5-fraction stereotactic radiosurgery (25-40 Gy in 5 fractions) with concurrent and adjuvant temozolomide."9.24Phase 1/2 Trial of 5-Fraction Stereotactic Radiosurgery With 5-mm Margins With Concurrent and Adjuvant Temozolomide in Newly Diagnosed Supratentorial Glioblastoma: Health-Related Quality of Life Results. ( Adler, JR; Azoulay, M; Chang, SD; Choi, CYH; Fujimoto, D; Gibbs, IC; Hancock, SL; Harraher, C; Harsh, GR; Jacobs, LR; Li, G; Modlin, LA; Nagpal, S; Pollom, EL; Recht, LD; Seiger, K; Soltys, SG; Thomas, RP; Tupper, L; von Eyben, R; Wynne, J, 2017)
"Bevacizumab plus bi-weekly temozolomide was well tolerated and may be a salvage regimen to be considered in a subset of patients with recurrent glioblastoma."9.24Phase II study of bi-weekly temozolomide plus bevacizumab for adult patients with recurrent glioblastoma. ( Ahmadi, MM; Badruddoja, MA; Kuzma, K; Mahadevan, D; Norton, T; Pazzi, M; Sanan, A; Schroeder, K; Scully, T, 2017)
"We characterized health-related quality of life (HRQoL), cognitive, and functional status in newly diagnosed glioblastoma (GBM) patients receiving Tumor treating fields (TTFields) with temozolomide (TMZ) versus TMZ alone in a planned interim analysis of a randomized phase III trial [NCT00916409], which showed significant improvement in progression-free and overall survival with TTFields/TMZ."9.24Health-related quality of life, cognitive screening, and functional status in a randomized phase III trial (EF-14) of tumor treating fields with temozolomide compared to temozolomide alone in newly diagnosed glioblastoma. ( Avgeropoulos, N; Benouaich-Amiel, A; David, C; Demireva, P; Goldlust, S; Kanner, AA; Mehdorn, M; Pannullo, S; Salmaggi, A; Silvani, A; Zhu, JJ, 2017)
"While our study failed to meet the primary endpoint for objective radiographic response, patients with high-risk low-grade glioma receiving adjuvant temozolomide demonstrated a high rate of radiographic stability and favorable survival outcomes while meaningfully delaying radiotherapy."9.24Chemotherapy for adult low-grade gliomas: clinical outcomes by molecular subtype in a phase II study of adjuvant temozolomide. ( Berger, MS; Butowski, N; Chang, SM; Clarke, JL; Costello, JF; Dayal, M; Haas-Kogan, DA; Lin, Y; Molinaro, AM; Nelson, S; Perry, A; Phillips, JJ; Prados, M; Wahl, M, 2017)
"The primary objective of this study was to compare the overall survival (OS) of patients with anaplastic astrocytoma (AA) treated with radiotherapy (RT) and either temozolomide (TMZ) or a nitrosourea (NU)."9.24Phase III randomized study of radiation and temozolomide versus radiation and nitrosourea therapy for anaplastic astrocytoma: results of NRG Oncology RTOG 9813. ( Aldape, KD; Bahary, JP; Barger, GR; Belanger, K; Bell, EH; Brachman, D; Brown, PD; Cairncross, JG; Chakravarti, A; Chang, S; Dolinskas, CA; Gilbert, MR; Hunter, G; Jaeckle, K; Mehta, M; Penas-Prado, M; Robins, HI; Schiff, D; Schultz, C; Shih, H; Werner-Wasik, M; Zhang, P, 2017)
"We performed a phase 2 trial of neoadjuvant temozolomide (TMZ), followed by hypofractionated accelerated radiation therapy (HART) with concurrent TMZ, and adjuvant TMZ in patients with newly diagnosed glioblastoma to determine whether neoadjuvant TMZ would safely improve outcomes in this group of patients prior to subsequent cytotoxic therapy."9.24A Phase 2 Trial of Neoadjuvant Temozolomide Followed by Hypofractionated Accelerated Radiation Therapy With Concurrent and Adjuvant Temozolomide for Patients With Glioblastoma. ( Abdulkarim, B; Corredor, AG; Guiot, MC; Owen, S; Panet-Raymond, V; Petrecca, K; Shenouda, G; Souhami, L, 2017)
"The purpose of this study was to determine the maximum tolerated dose (MTD), recommended phase II dose (RPTD), safety, and pharmacokinetics of ABT-414 plus radiation and temozolomide in newly diagnosed glioblastoma."9.24Efficacy and safety results of ABT-414 in combination with radiation and temozolomide in newly diagnosed glioblastoma. ( Ansell, P; Fichtel, L; Fischer, J; Gan, HK; Gomez, E; Holen, KD; Kumthekar, P; Lassman, AB; Lee, HJ; Mandich, H; Merrell, R; Munasinghe, W; Reardon, DA; Roberts-Rapp, L; Scott, AM; Sulman, EP; van den Bent, M; Xiong, H, 2017)
"There is a need for a more refined, molecularly based classification model for glioblastoma (GBM) in the temozolomide era."9.24Molecular-Based Recursive Partitioning Analysis Model for Glioblastoma in the Temozolomide Era: A Correlative Analysis Based on NRG Oncology RTOG 0525. ( Aldape, K; Barnholtz-Sloan, JS; Becker, AP; Bell, EH; Blumenthal, DT; Brachman, D; Bredel, M; Brown, PD; Chakravarti, A; Curran, W; Flickinger, J; Gilbert, MR; Glass, J; Grosu, AL; Klimowicz, AC; Lee, RJ; Magliocco, A; McElroy, JP; Mehta, M; Pugh, SL; Robe, P; Salavaggione, AL; Souhami, L; Stupp, R; Won, M, 2017)
"Temozolomide (TMZ), an imidazotetrazine, is a second-generation DNA alkylating agent used as a first-line treatment of glioblastoma multiforme (GBM)."9.22Polymeric and small molecule-conjugates of temozolomide as improved therapeutic agents for glioblastoma multiforme. ( Chitkara, D; Jatyan, R; Karthik, YG; Mittal, A; Sahel, DK; Singh, P, 2022)
"To evaluate the safety and efficacy of nimotuzumab, a humanized monoclonal antibody specific for the epidermal growth factor receptor (EGFR), in combination with temozolomide (TMZ) and radiation therapy (RT) in the treatment of newly diagnosed glioblastoma (GBM) in Chinese patients."9.22Nimotuzumab, a humanized monoclonal antibody specific for the EGFR, in combination with temozolomide and radiation therapy for newly diagnosed glioblastoma multiforme: First results in Chinese patients. ( Chen, S; Dai, JZ; Pan, L; Sheng, XF; Wang, Y, 2016)
"We report on a phase II clinical trial to determine the effect of a concurrent ultra-fractionated radiotherapy and temozolomide treatment in inoperable glioblastoma patients."9.22A concurrent ultra-fractionated radiation therapy and temozolomide treatment: A promising therapy for newly diagnosed, inoperable glioblastoma. ( Beauchesne, P; Bernier, V; Carnin, C; Faure, G; Gorlia, T; Noel, G; Pedeux, R; Quetin, P; Quillien, V, 2016)
"This study tested the hypothesis that ABT-888 (velparib), a poly (ADP-ribose) polymerase (PARP) inhibitor, can modulate temozolomide (TMZ) resistance in recurrent TMZ refractory glioblastoma patients."9.22A randomized phase I/II study of ABT-888 in combination with temozolomide in recurrent temozolomide resistant glioblastoma: an NRG oncology RTOG group study. ( Cavaliere, R; Chakravarti, A; Chmura, SJ; Colman, H; de Groot, JF; Gilbert, MR; Grimm, SA; Kee, AY; Kesari, S; Krauze, A; Lieberman, FS; Mehta, M; Mohile, N; Robins, HI; Trotti, AM; Wang, F; Zhang, P, 2016)
"This phase II study was conducted to determine the efficacy and safety of metronomic temozolomide (TMZ) in combination with irinotecan in glioblastoma (GB) at first relapse."9.22Phase II trial of irinotecan and metronomic temozolomide in patients with recurrent glioblastoma. ( Balañá, C; Benavides, M; Fleitas, T; Gallego, O; Gil-Gil, M; Martínez-Sales, V; Palomero, I; Pérez-Segura, P; Reche, E; Reynés, G; Vaz, MA; Vila, V, 2016)
"Adding temozolomide (TMZ) to radiation for patients with newly-diagnosed anaplastic astrocytomas (AAs) is common clinical practice despite the lack of prospective studies demonstrating a survival advantage."9.22The role of temozolomide in the management of patients with newly diagnosed anaplastic astrocytoma: a comparison of survival in the era prior to and following the availability of temozolomide. ( Abuali, I; Grossman, SA; Lu, Y; Strowd, RE; Ye, X, 2016)
"The proposed use of bevacizumab with radiotherapy/temozolomide for newly diagnosed glioblastoma raised potential safety concerns."9.22Bevacizumab, temozolomide, and radiotherapy for newly diagnosed glioblastoma: comprehensive safety results during and after first-line therapy. ( Chinot, OL; Cloughesy, T; Dhar, S; Garcia, J; Henriksson, R; Mason, W; Nishikawa, R; Pozzi, E; Saran, F; Wick, W, 2016)
"Following maximal surgical resection, newly diagnosed children with nonmetastatic high-grade glioma underwent involved field radiotherapy with concurrent temozolomide."9.22Phase 2 study of concurrent radiotherapy and temozolomide followed by temozolomide and lomustine in the treatment of children with high-grade glioma: a report of the Children's Oncology Group ACNS0423 study. ( Brat, DJ; Burger, PC; Buxton, A; Cohen, KJ; Eckel, SP; Hamilton, RL; Jakacki, RI; Krailo, MD; Lavey, RS; Pollack, IF; Rosenblum, MK; Zhou, T, 2016)
"To evaluate the maximum tolerated dose of simultaneous integrated-boost intensity-modulated radiotherapy (SIB-IMRT) associated with temozolomide in patients with glioblastoma."9.22A phase I dose escalation study using simultaneous integrated-boost IMRT with temozolomide in patients with unifocal glioblastoma. ( Bernier, V; Blanchard, N; Bonnetain, F; Dalban, C; Lagneau, É; Maingon, P; Mazoyer, F; Mirjolet, C; Noël, G; Truc, G, 2016)
" Patients with MGMT unmethylated glioblastoma (n = 111) were randomized 1:1 between standard chemo-radiotherapy with temozolomide or radiotherapy plus weekly temsirolimus (25 mg)."9.22Phase II Study of Radiotherapy and Temsirolimus versus Radiochemotherapy with Temozolomide in Patients with Newly Diagnosed Glioblastoma without MGMT Promoter Hypermethylation (EORTC 26082). ( Bady, P; Brandes, AA; Campone, M; Frenel, JS; Golfinopoulos, V; Gorlia, T; Hamou, MF; Hegi, ME; Homicsko, K; Hopkins, K; Kosch, M; Lhermitte, B; Marosi, C; Pesce, G; Platten, M; Ricard, D; Roth, P; Steuve, J; Stupp, R; Taphoorn, MJ; van den Bent, MJ; Villa, S; Weller, M; Weyerbrock, A; Wick, A; Wick, W, 2016)
"Overall, there was no significant difference in progression-free survival in patients with low-grade glioma when treated with either radiotherapy alone or temozolomide chemotherapy alone."9.22Temozolomide chemotherapy versus radiotherapy in high-risk low-grade glioma (EORTC 22033-26033): a randomised, open-label, phase 3 intergroup study. ( Balana, C; Baumert, BG; Brandes, AA; Bravo-Marques, J; Bromberg, JE; Capper, D; Chinot, O; Clement, PM; Dhermain, F; Dif, N; Enting, R; Feuvret, L; Gijtenbeek, JMM; Gorlia, T; Hartmann, C; Hassel, MB; Hegi, ME; Hoang-Xuan, K; Kantor, G; Kros, JM; Kurscheid, S; Lacombe, D; Marosi, C; Mason, WP; Nordal, RA; Rees, J; Reijneveld, JC; Reni, M; Rossiter, JP; Ryan, G; Stupp, R; Taphoorn, MJB; Thiessen, B; Tzuk-Shina, T; van den Bent, MJ; von Deimling, A; Wick, W, 2016)
"Temozolomide (TMZ) administered daily with radiation therapy (RT) for 6 weeks, followed by adjuvant TMZ for 6 cycles, is the standard therapy for newly diagnosed glioblastoma (GBM) patients."9.20Clinical and Genetic Factors Associated With Severe Hematological Toxicity in Glioblastoma Patients During Radiation Plus Temozolomide Treatment: A Prospective Study. ( Amadori, A; Berti, F; Bertorelle, R; Della Puppa, A; Farina, P; Lombardi, G; Marcato, R; Rumiato, E; Sacchetto, V; Saggioro, D; Zagonel, V; Zustovich, F, 2015)
"This phase I/II trial evaluated the maximum tolerated dose (MTD) and pharmacokinetics of afatinib plus temozolomide as well as the efficacy and safety of afatinib as monotherapy (A) or with temozolomide (AT) vs temozolomide monotherapy (T) in patients with recurrent glioblastoma (GBM)."9.20Phase I/randomized phase II study of afatinib, an irreversible ErbB family blocker, with or without protracted temozolomide in adults with recurrent glioblastoma. ( Cong, J; Cseh, A; Eisenstat, DD; Fu, Y; Kavan, P; Mason, WP; Mathieu, D; Nabors, LB; Perry, JR; Phuphanich, S; Reardon, DA; Shapiro, W; Wind, S, 2015)
"Chemoradiation, followed by adjuvant temozolomide, is the standard treatment for newly diagnosed glioblastoma."9.20Randomized phase II adjuvant factorial study of dose-dense temozolomide alone and in combination with isotretinoin, celecoxib, and/or thalidomide for glioblastoma. ( Aldape, KD; Chang, EL; Colman, H; Conrad, CA; De Groot, JF; Fisch, MJ; Floyd, JD; Giglio, P; Gilbert, MR; Gonzalez, J; Groves, MD; Hess, KR; Hsu, SH; Lagrone, LW; Levin, VA; Loghin, ME; Mahajan, A; Penas-Prado, M; Puduvalli, VK; Salacz, ME; Volas-Redd, G; Woo, SY; Yung, WK, 2015)
"To improve the therapeutic index of whole-brain radiation therapy (WBRT) in the treatment of brain metastases (BM) from breast cancer, we investigated the efficacy and safety of WBRT combined with temozolomide (TMZ) in this population."9.20Phase II randomized study of whole-brain radiation therapy with or without concurrent temozolomide for brain metastases from breast cancer. ( Bourgier, C; Cao, KI; Gerber, S; Gobillion, A; Kirova, YM; Le Scodan, R; Lebas, N; Levy, C; Pierga, JY; Savignoni, A, 2015)
" We evaluated the efficacy and toxicity of hypofractionated intensity-modulated radiation therapy with concurrent and adjuvant temozolomide and bevacizumab in patients with newly diagnosed glioblastoma."9.20Phase II trial of hypofractionated intensity-modulated radiation therapy combined with temozolomide and bevacizumab for patients with newly diagnosed glioblastoma. ( Carlson, JA; Chen, C; Damek, DM; Gaspar, LE; Kavanagh, BD; Kleinschmidt-DeMasters, BK; Lillehei, KO; Ney, DE; Reddy, K; Waziri, AE, 2015)
"Patients with a newly diagnosed glioblastoma multiforme (GBM) have a high risk of recurrent disease with a dismal outcome despite intensive treatment of sequential surgery and chemoradiotherapy with temozolomide (TMZ), followed by TMZ as a single agent."9.20Bevacizumab in combination with radiotherapy and temozolomide for patients with newly diagnosed glioblastoma multiforme. ( Reijneveld, JC; Richel, DJ; Stalpers, LJ; van Furth, WR; van Linde, ME; Verheul, HM; Verhoeff, JJ, 2015)
"Rechallenge with temozolomide (TMZ) at first progression of glioblastoma after temozolomide chemoradiotherapy (TMZ/RT→TMZ) has been studied in retrospective and single-arm prospective studies, applying temozolomide continuously or using 7/14 or 21/28 days schedules."9.20MGMT Promoter Methylation Is a Strong Prognostic Biomarker for Benefit from Dose-Intensified Temozolomide Rechallenge in Progressive Glioblastoma: The DIRECTOR Trial. ( Bähr, O; Felsberg, J; Goldbrunner, R; Hau, P; Herrlinger, U; Homicsko, K; Hüsing, J; Kästner, B; Ketter, R; Kollias, S; Marosi, C; Meixensberger, J; Nikkhah, G; Pichler, J; Platten, M; Reifenberger, G; Sabel, MC; Schlegel, U; Schnell, O; Steinbach, JP; Stupp, R; Tabatabai, G; Tonn, JC; Vajkoczy, P; Weller, M; Wick, A; Wick, W; Wirsching, HG, 2015)
"Radiation Therapy Oncology Group (RTOG) 0424 was a phase 2 study of a high-risk low-grade glioma (LGG) population who were treated with temozolomide (TMZ) and radiation therapy (RT), and outcomes were compared to those of historical controls."9.20Phase 2 study of temozolomide-based chemoradiation therapy for high-risk low-grade gliomas: preliminary results of Radiation Therapy Oncology Group 0424. ( Bahary, JP; Brachman, DG; Chakravarti, A; Coons, SW; Fisher, BJ; Hu, C; Lesser, GJ; Liu, J; Macdonald, DR; Mehta, M; Ryu, S; Werner-Wasik, M, 2015)
"To investigate the safety of combined Wilms tumor 1 peptide vaccination and temozolomide treatment of glioblastoma, a phase I clinical trial was designed."9.20Wilms tumor 1 peptide vaccination combined with temozolomide against newly diagnosed glioblastoma: safety and impact on immunological response. ( Arita, N; Chiba, Y; Hashimoto, N; Hosen, N; Izumoto, S; Kagawa, N; Kijima, N; Kinoshita, M; Morimoto, S; Morita, S; Nakajima, H; Nishida, S; Oji, Y; Oka, Y; Sakamoto, J; Sugiyama, H; Tsuboi, A; Yoshimine, T, 2015)
"The purpose of phase 1 was to determine the maximum tolerated dose (MTD) of motexafin gadolinium (MGd) given concurrently with temozolomide (TMZ) and radiation therapy (RT) in patients with newly diagnosed supratentorial glioblastoma multiforme (GBM)."9.20Phase 1/2 trials of Temozolomide, Motexafin Gadolinium, and 60-Gy fractionated radiation for newly diagnosed supratentorial glioblastoma multiforme: final results of RTOG 0513. ( Ashby, LS; Bovi, JA; Brachman, DG; Curran, WP; Dunbar, EM; Narayan, S; Pugh, SL; Robins, HI; Rockhill, JK; Thomas, TA; Won, M, 2015)
"Temozolomide (TMZ) and BCNU have demonstrated anti-glioma synergism in preclinical models."9.20BCNU wafer placement with temozolomide (TMZ) in the immediate postoperative period after tumor resection followed by radiation therapy with TMZ in patients with newly diagnosed high grade glioma: final results of a prospective, multi-institutional, phase ( Ashby, L; Asher, AL; Blaker, BD; Boltes, P; Brick, W; Burri, SH; Heideman, BE; Judy, K; Kelly, R; Norton, HJ; Prabhu, RS; Sumrall, AL; Symanowski, JT; Wiggins, WF, 2015)
"This phase I study aimed to evaluate safety, maximum tolerated dose, pharmacokinetics, pharmacodynamics, and preliminary efficacy of voxtalisib (SAR245409, XL765), a pan-class I phosphoinositide 3-kinase (PI3K) and mammalian target of rapamycin (mTOR) inhibitor, in combination with temozolomide (TMZ), with or without radiation therapy (RT), in patients with high-grade glioma."9.20Phase I dose-escalation study of the PI3K/mTOR inhibitor voxtalisib (SAR245409, XL765) plus temozolomide with or without radiotherapy in patients with high-grade glioma. ( Ahluwalia, MS; Cloughesy, TF; Egile, C; Fathallah-Shaykh, HM; Jiang, J; Lager, JJ; Laird, AD; Mohile, N; Omuro, A; Tang, J; Wen, PY, 2015)
"The aim of this prospective and multicentric phase II study was to evaluate the efficacy and safety of temozolomide (TMZ) and bevacizumab (BV) in patients (pts) with recurrent glioblastoma (GB), previously treated with chemoradiotherapy and at least three cycles of adjuvant TMZ."9.20A phase II study of feasibility and toxicity of bevacizumab in combination with temozolomide in patients with recurrent glioblastoma. ( Balañá, C; Belda-Iniesta, C; Berrocal, A; Capellades, J; Gallego, O; Gil-Gil, M; La Orden, B; Ordoñez, JM; Pérez-Segura, P; Reynés, G; Sepúlveda, JM, 2015)
"We report on the long-term results of a phase II study of pre-irradiation temozolomide followed by concurrent temozolomide and radiotherapy (RT) in patients with newly diagnosed anaplastic oligodendroglioma (AO) and mixed anaplastic oligoastrocytoma."9.20Phase II trial of pre-irradiation and concurrent temozolomide in patients with newly diagnosed anaplastic oligodendrogliomas and mixed anaplastic oligoastrocytomas: long term results of RTOG BR0131. ( Brachman, DG; Giannini, C; Hu, C; Jenkins, RB; Laack, NN; Macdonald, DR; Mehta, MP; Peereboom, DM; Shrieve, DC; Souhami, L; Suh, JH; Vogelbaum, MA, 2015)
"Valproic acid (VPA) is an antiepileptic agent with histone deacetylase inhibitor (HDACi) activity shown to sensitize glioblastoma (GBM) cells to radiation in preclinical models."9.20A Phase 2 Study of Concurrent Radiation Therapy, Temozolomide, and the Histone Deacetylase Inhibitor Valproic Acid for Patients With Glioblastoma. ( Camphausen, K; Chang, MG; Fine, HA; Holdford, DJ; Krauze, AV; Myrehaug, SD; Shih, J; Smith, S; Tofilon, PJ, 2015)
"In this multicenter, double-blind trial, adults with unresectable stage III or IV metastatic melanoma were randomized 1:1:1 to TMZ plus veliparib 20 or 40 mg, or placebo twice daily."9.20Randomized phase II study evaluating veliparib (ABT-888) with temozolomide in patients with metastatic melanoma. ( Chyla, B; Daud, A; Falotico, N; Friedlander, P; Giranda, VL; Hamid, O; Jiang, F; Luo, Y; McArthur, GA; McKee, M; McKeegan, E; Middleton, MR; Mostafa, NM; Plummer, R; Qian, J; Zhu, M, 2015)
"Iniparib is a prodrug that converts to highly reactive cytotoxic metabolites intracellularly with activity in preclinical glioma models."9.20Phase I study of iniparib concurrent with monthly or continuous temozolomide dosing schedules in patients with newly diagnosed malignant gliomas. ( Blakeley, JO; Chi, AS; Desideri, S; Emmons, G; Garcia Ribas, I; Grossman, SA; Mikkelsen, T; Nabors, LB; Peereboom, D; Rosenfeld, MR; Supko, JG; Ye, X, 2015)
"To evaluate the efficacy and safety of TTFields used in combination with temozolomide maintenance treatment after chemoradiation therapy for patients with glioblastoma."9.20Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial. ( Barnett, GH; Caroli, M; Chen, TC; Desai, R; Engelhard, HH; Fink, KL; Hegi, ME; Henson, JW; Honnorat, J; Hottinger, AF; Idbaih, A; Kanner, AA; Kesari, S; Kew, Y; Kirson, ED; Landolfi, J; Lieberman, F; Palti, Y; Ram, Z; Silvani, A; Sroubek, J; Steinberg, DM; Stupp, R; Taillibert, S; Taylor, LP; Toms, SA; Tran, DD; Tran, ND; Weinberg, U; Zhu, JJ, 2015)
"To evaluate the efficacy of limited margins intensity-modulated radiotherapy (IMRT) with temozolomide chemotherapy in patients with malignant glioma, and explore the prognostic factors of malignant glioma."9.20[Randomized controlled study of limited margins IMRT and temozolomide chemotherapy in patients with malignant glioma]. ( Cao, Y; Sun, J; Yang, X; Zhang, W, 2015)
"Adult patients with newly surgical diagnosed glioblastoma were randomly assigned to receive either temozolomide or semustine after radiation treatment."9.19Gain of function of mutant TP53 in glioblastoma: prognosis and response to temozolomide. ( Chen, JX; Liu, JP; Liu, YH; Mao, Q; Wang, X; You, C, 2014)
" We sought to determine whether the addition of a vascular endothelial growth factor (VEGF) signaling inhibitor (cediranib) to conventional CRT had an impact on the frequency of PsP, by comparing two groups of patients with newly diagnosed glioblastoma before, during, and after CRT."9.19Low incidence of pseudoprogression by imaging in newly diagnosed glioblastoma patients treated with cediranib in combination with chemoradiation. ( Batchelor, TT; Emblem, KE; Gerstner, ER; Jain, RK; Jennings, D; Kalpathy-Cramer, J; Pinho, MC; Polaskova, P; Rosen, BR; Sorensen, AG; Wen, PY, 2014)
"We conducted a phase I study to determine (a) the maximum tolerated dose of peri-radiation therapy temozolomide (TMZ) and (b) the safety of a selected hypofractionated intensity modulated radiation therapy (HIMRT) regimen in glioblastoma multiforme (GBM) patients."9.19Hypofractionated intensity modulated radiotherapy with temozolomide in newly diagnosed glioblastoma multiforme. ( Ammirati, M; Chotai, S; Grecula, J; Lamki, T; Newton, H; Wei, L, 2014)
"The integrin antagonist cilengitide has been explored as an adjunct with anti-angiogenic properties to standard of care temozolomide chemoradiotherapy (TMZ/RT → TMZ) in newly diagnosed glioblastoma."9.19Cilengitide treatment of newly diagnosed glioblastoma patients does not alter patterns of progression. ( Clément, PM; Eisele, AC; Eisele, G; Krex, D; Neyns, B; Nikkhah, G; Ochsenbein, A; Picard, M; Schlegel, U; Simon, M; Stupp, R; Tabatabai, G; Tonn, J; Weller, M; Wick, A; Wick, W, 2014)
"Surgery followed by radiotherapy and concomitant and adjuvant temozolomide is standard therapy in newly diagnosed glioblastoma multiforme (GBM)."9.19Neoadjuvant bevacizumab and irinotecan versus bevacizumab and temozolomide followed by concomitant chemoradiotherapy in newly diagnosed glioblastoma multiforme: A randomized phase II study. ( Ask, A; Costa, JC; Engelholm, S; Grunnet, K; Hansen, S; Hofland, KF; Kristiansen, C; Lassen, U; Muhic, A; Poulsen, HS; Schultz, HP; Sorensen, M; Thomsen, C, 2014)
"To assess the effect and toxicity of hypofractionated high-dose intensity modulated radiation therapy (IMRT) with concurrent and adjuvant temozolomide (TMZ) in 46 patients with newly diagnosed glioblastoma multiforme (GBM)."9.19Phase 2 trial of hypofractionated high-dose intensity modulated radiation therapy with concurrent and adjuvant temozolomide for newly diagnosed glioblastoma. ( Hara, R; Hasegawa, Y; Hatano, K; Iuchi, T; Kawasaki, K; Kodama, T; Sakaida, T; Yokoi, S, 2014)
"Standard therapy for newly diagnosed glioblastoma is radiotherapy plus temozolomide."9.19Bevacizumab plus radiotherapy-temozolomide for newly diagnosed glioblastoma. ( Abrey, L; Brandes, AA; Carpentier, AF; Cernea, D; Chinot, OL; Cloughesy, T; Henriksson, R; Hilton, M; Hoang-Xuan, K; Kavan, P; Mason, W; Nishikawa, R; Saran, F; Wick, W, 2014)
"Prognosis of unresectable glioblastoma (GB) remains poor, despite temozolomide (TMZ)-based chemoradiation."9.19Randomized phase II trial of irinotecan and bevacizumab as neo-adjuvant and adjuvant to temozolomide-based chemoradiation compared with temozolomide-chemoradiation for unresectable glioblastoma: final results of the TEMAVIR study from ANOCEF†. ( Bonnetain, F; Campello, C; Castera, D; Chauffert, B; Chinot, O; Dalban, C; Durando, X; Fabbro, M; Feuvret, L; Frappaz, D; Frenay, M; Ghiringhelli, F; Guillamo, JS; Honnorat, J; Schott, R; Skrzypski, J; Taillandier, L; Taillia, H; Tennevet, I, 2014)
"The objective of this study was to report the patterns of failure in patients with glioblastoma multiforme (GBM) treated on a phase II trial of hypofractionated intensity-modulated radiotherapy (hypo-IMRT) with concurrent and adjuvant temozolomide (TMZ)."9.19Hypofractionated intensity-modulated radiotherapy with temozolomide chemotherapy may alter the patterns of failure in patients with glioblastoma multiforme. ( Chen, C; Gaspar, LE; Kavanagh, BD; Reddy, K, 2014)
" The primary objective of this trial was to determine the maximum tolerated dose (MTD) and efficacy of HCQ in combination with radiation therapy (RT) and temozolomide (TMZ) for newly diagnosed glioblastoma (GB)."9.19A phase I/II trial of hydroxychloroquine in conjunction with radiation therapy and concurrent and adjuvant temozolomide in patients with newly diagnosed glioblastoma multiforme. ( Amaravadi, RK; Brem, S; Chang, YC; Davis, LE; Desideri, S; Fisher, J; Grossman, SA; Heitjan, DF; Hu, J; McAfee, Q; Mikkelson, T; O'Dwyer, PJ; Piao, S; Pontiggia, L; Rosenfeld, MR; Supko, JG; Tan, KS; Troxel, AB; Wang, D; Ye, X, 2014)
"Temozolomide (TMZ) may enhance antitumor immunity in patients with glioblastoma multiforme (GBM)."9.19Phase I/IIa trial of fractionated radiotherapy, temozolomide, and autologous formalin-fixed tumor vaccine for newly diagnosed glioblastoma. ( Abe, T; Hashimoto, K; Ikuta, S; Ishihara, T; Ishikawa, E; Karasawa, K; Maruyama, T; Matsuda, M; Matsumura, A; Matsutani, M; Muragaki, Y; Nakazato, Y; Ohno, T; Tsuboi, K; Uemae, Y; Yamamoto, T, 2014)
" We conducted a phase II trial in newly diagnosed glioblastoma utilizing a novel hypofractionated stereotactic radiotherapy (HFSRT) schedule combined with temozolomide and bevacizumab."9.19Phase II study of bevacizumab, temozolomide, and hypofractionated stereotactic radiotherapy for newly diagnosed glioblastoma. ( Abrey, LE; Barradas-Panchal, R; Baser, RE; Beal, K; Brennan, CW; Chan, TA; Correa, DD; DeAngelis, LM; Faivre, G; Gavrilovic, IT; Grommes, C; Gutin, P; Hormigo, A; Huse, JT; Kaley, TJ; Karimi, S; Lassman, AB; Mellinghoff, I; Nolan, C; Omuro, A; Panageas, KS; Pentsova, E; Reiner, AS; Sanchez, J; Tabar, V; Zhang, J, 2014)
" Data from phase 2 trials suggest that it has antitumour activity as a single agent in recurrent glioblastoma and in combination with standard temozolomide chemoradiotherapy in newly diagnosed glioblastoma (particularly in tumours with methylated MGMT promoter)."9.19Cilengitide combined with standard treatment for patients with newly diagnosed glioblastoma with methylated MGMT promoter (CENTRIC EORTC 26071-22072 study): a multicentre, randomised, open-label, phase 3 trial. ( Adamska, K; Aldape, KD; Brandes, AA; Erridge, SC; Gorlia, T; Grujicic, D; Gupta, T; Hau, P; Hegi, ME; Herrlinger, U; Hicking, C; Hong, YK; Kim, CY; Kortmann, RD; Lhermitte, B; Markivskyy, A; McBain, C; Nabors, LB; Nam, DH; Perry, J; Picard, M; Pietsch, T; Rao, N; Reardon, DA; Schnell, O; Shen, CC; Steinbach, JP; Stupp, R; Taphoorn, MJ; Tarnawski, R; Thurzo, L; Tonn, JC; van den Bent, MJ; Weller, M; Weyerbrock, A; Wick, W; Wiegel, T, 2014)
" The primary objective of this study was to determine the safety of the combination of PPX with temozolomide and concurrent radiation for high-grade gliomas."9.19Paclitaxel poliglumex, temozolomide, and radiation for newly diagnosed high-grade glioma: a Brown University Oncology Group Study. ( Boxerman, J; Cielo, D; Constantinou, M; Dipetrillo, T; Donahue, J; Elinzano, H; Evans, D; Goldman, M; Isdale, D; Jeyapalan, S; Kinsella, T; Mantripragada, K; Oyelese, A; Puthawala, Y; Rosati, K; Safran, H; Santaniello, A; Stopa, E, 2014)
"To determine the safety and efficacy of hypofractionated intensity modulated radiation therapy (Hypo-IMRT) using helical tomotherapy (HT) with concurrent low dose temozolomide (TMZ) followed by adjuvant TMZ in patients with glioblastoma multiforme (GBM)."9.17Phase I study of hypofractionated intensity modulated radiation therapy with concurrent and adjuvant temozolomide in patients with glioblastoma multiforme. ( Abdulkarim, B; Fallone, G; Field, C; Fulton, D; Ghosh, S; Jastaniyah, N; Le, D; Mackenzie, M; Murtha, A; Patel, S; Pervez, N; Roa, W, 2013)
"A multicenter, two stage phase II study, investigated irinotecan plus temozolomide in children with newly diagnosed high grade glioma."9.17A phase II single-arm study of irinotecan in combination with temozolomide (TEMIRI) in children with newly diagnosed high grade glioma: a joint ITCC and SIOPE-brain tumour study. ( Ashley, D; Breazna, A; Cisar, L; Clausen, N; Cruz-Martinez, O; Dorman, A; Elliott, M; English, M; Frappaz, D; Fuster, JL; Geoerger, B; Gesner, L; Grill, J; Hargrave, D; Icher, C; Leblond, P; Perilongo, G; Pietsch, T; Rialland, X, 2013)
"The alkylating agent temozolomide (TMZ) is widely used for the treatment of gliomas."9.17Secondary hematological malignancies associated with temozolomide in patients with glioma. ( Miyakita, Y; Momota, H; Narita, Y; Shibui, S, 2013)
"Among patients with glioblastoma (GBM) who progress on standard temozolomide, the optimal therapy is unknown."9.17Phase 2 study of dose-intense temozolomide in recurrent glioblastoma. ( Batchelor, TT; Beroukhim, R; Doherty, L; Drappatz, J; Fadul, CE; Hammond, SN; Lafrankie, D; Lee, EQ; Lesser, GJ; Ligon, KL; Lis, R; Muzikansky, A; Norden, AD; Plotkin, SR; Reardon, DR; Rosenfeld, MR; Smith, K; Stack, EC; Tafoya, V; Wen, PY; Zhu, JJ, 2013)
"To describe the quality of life (QOL) in elderly patients with glioblastoma (GBM) treated with an abbreviated course of radiation therapy (RT; 40 Gy in 15 fractions) plus concomitant and adjuvant temozolomide (TMZ)."9.17Health-related quality of life in elderly patients with newly diagnosed glioblastoma treated with short-course radiation therapy plus concomitant and adjuvant temozolomide. ( Baldoni, A; De Sanctis, V; Enrici, RM; Esposito, V; Lanzetta, G; Minniti, G; Scaringi, C, 2013)
"The prognostic role of O(6)-methylguanine-DNA methyltransferase (MGMT) promoter methylation in glioblastoma patients treated with carmustine (BCNU) wafer implantation is unclear."9.17MGMT promoter methylation status and prognosis of patients with primary or recurrent glioblastoma treated with carmustine wafers. ( Bock, HC; Brück, W; Doerner, L; Felsberg, J; Giese, A; Gutenberg, A; Mehdorn, HM; Reifenberger, G; Roggendorf, W; Westphal, M, 2013)
"To determine the safety of the mammalian target of rapamycin inhibitor everolimus (RAD001) administered daily with concurrent radiation and temozolomide in newly diagnosed glioblastoma patients."9.17RTOG 0913: a phase 1 study of daily everolimus (RAD001) in combination with radiation therapy and temozolomide in patients with newly diagnosed glioblastoma. ( Chinnaiyan, P; Corn, BW; Dipetrillo, TA; Mehta, MP; Rojiani, AM; Wen, PY; Wendland, M; Won, M, 2013)
"To report health-related quality of life (HRQOL) in glioblastoma (GBM) patients treated on a phase II trial of hypofractionated intensity-modulated radiotherapy (hypo-IMRT) with temozolomide (TMZ)."9.17Prospective evaluation of health-related quality of life in patients with glioblastoma multiforme treated on a phase II trial of hypofractionated IMRT with temozolomide. ( Chen, C; Damek, DM; Gaspar, LE; Kavanagh, BD; Lillehei, KO; Ney, D; Reddy, K; Waziri, A, 2013)
"The current standard-of-care for glioblastoma (GBM) is represented by concomitant radiotherapy (RT) and temozolomide (TMZ), according to Stupp's protocol."9.17Continuous tamoxifen and dose-dense temozolomide in recurrent glioblastoma. ( Caroli, M; Carrabba, G; DI Cristofori, A; Lanfranchi, G; Menghetti, C; Rampini, P, 2013)
"To investigate the impact of nonstandard concomitant temozolomide (TMZ) administration in two prospective phase II studies for glioblastoma (GBM)."9.17Concurrent and adjuvant temozolomide-based chemoradiotherapy schedules for glioblastoma. Hypotheses based on two prospective phase II trials. ( Alitto, AR; Anile, C; Balducci, M; Chiesa, S; Colosimo, C; D'Agostino, GR; De Bonis, P; Fiorentino, A; Frascino, V; Mangiola, A; Mantini, G; Mattiucci, GC; Valentini, V, 2013)
"Radiotherapy with concomitant and adjuvant temozolomide is the standard of care for newly diagnosed glioblastoma (GBM)."9.17Dose-dense temozolomide for newly diagnosed glioblastoma: a randomized phase III clinical trial. ( Aldape, KD; Armstrong, TS; Baumert, B; Blumenthal, DT; Brown, PD; Chakravarti, A; Curran, WJ; Erridge, S; Gilbert, MR; Hegi, ME; Hopkins, KI; Jaeckle, KA; Mahajan, A; Mehta, MP; Schultz, CJ; Stupp, R; Tzuk-Shina, T; Wang, M; Wefel, JS; Won, M, 2013)
"Radiation Therapy Oncology Group trial 0525 tested whether dose-intensifying temozolomide versus standard chemoradiotherapy improves overall survival (OS) or progression-free survival (PFS) in newly diagnosed glioblastoma."9.17Net clinical benefit analysis of radiation therapy oncology group 0525: a phase III trial comparing conventional adjuvant temozolomide with dose-intensive temozolomide in patients with newly diagnosed glioblastoma. ( Armstrong, TS; Bottomley, A; Brachman, DG; Choucair, AK; Coens, C; Gilbert, MR; Mehta, M; Mendoza, TR; Wang, M; Wefel, JS; Werner-Wasik, M; Won, M, 2013)
" Multiple glioma cell lines were analyzed for viability after treatment with radiation, temozolomide, or sorafenib or combinations of them."9.17A phase I study of the combination of sorafenib with temozolomide and radiation therapy for the treatment of primary and recurrent high-grade gliomas. ( Andrews, DW; Camphausen, K; Den, RB; Dicker, AP; Dougherty, E; Friedman, DP; Glass, J; Green, MR; Hegarty, S; Hyslop, T; Kamrava, M; Lawrence, YR; Marinucchi, M; Sheng, Z; Werner-Wasik, M, 2013)
"We performed a dose-escalation trial to determine the maximum tolerated dose (MTD) of intensity-modulated radiotherapy (IMRT) with standard concurrent and sequential-dose temozolomide (TMZ) in patients with glioblastoma multiforme."9.17Accelerated intensity-modulated radiotherapy plus temozolomide in patients with glioblastoma: a phase I dose-escalation study (ISIDE-BT-1). ( Balducci, M; Cilla, S; Deodato, F; Ferro, M; Macchia, G; Massaccesi, M; Morganti, AG; Valentini, V, 2013)
"In this phase II trial, we investigated the efficacy of a metronomic temozolomide schedule in the treatment of recurrent malignant gliomas (MGs)."9.17Phase II trial of continuous low-dose temozolomide for patients with recurrent malignant glioma. ( Abrey, LE; Chan, TA; Deangelis, LM; Gavrilovic, IT; Heguy, A; Hormigo, A; Hottinger, AF; Huse, JT; Kaley, TJ; Kaufman, A; Khasraw, M; Lassman, AB; Mellinghoff, I; Nolan, CP; Omuro, A; Panageas, KS; Reiner, AS; Salvant, C, 2013)
"We undertook this phase I study to investigate the feasibility of the combination of temozolomide (TMZ) and lapatinib (LP) and to define the maximum tolerated dose (MTD) of LP in patients with relapsed high-grade gliomas."9.17A phase I study of temozolomide and lapatinib combination in patients with recurrent high-grade gliomas. ( Bobos, M; Chrisafi, S; Fountzilas, G; Karavasilis, V; Kotoula, V; Lambaki, S; Pentheroudakis, G; Televantou, D, 2013)
"Locoregional chemotherapy with carmustine wafers, positioned at surgery and followed by radiation therapy, has been shown to prolong survival in patients with newly diagnosed glioblastoma, as has concomitant radiochemotherapy with temozolomide."9.17Prospective study of carmustine wafers in combination with 6-month metronomic temozolomide and radiation therapy in newly diagnosed glioblastoma: preliminary results. ( Casali, C; Ciusani, E; Dimeco, F; Fariselli, L; Gaviani, P; Guzzetti, S; Maccagnano, C; Marchetti, M; Milanesi, I; Pollo, B; Salmaggi, A; Silvani, A; Solero, CL, 2013)
"To determine the safety of the addition of bevacizumab to standard radiation therapy and daily temozolomide for newly diagnosed glioblastoma multiforme (GBM)."9.16Addition of bevacizumab to standard radiation therapy and daily temozolomide is associated with minimal toxicity in newly diagnosed glioblastoma multiforme. ( Bailey, L; Desjardins, A; Friedman, A; Friedman, HS; Herndon, JE; Kirkpatrick, JP; Marcello, J; Peters, KB; Reardon, DA; Sampson, J; Threatt, S; Vredenburgh, JJ, 2012)
"The new standard treatment of glioblastoma multiforme is concurrent radiotherapy (RT) and temozolomide."9.16Phase I clinical trial assessing temozolomide and tamoxifen with concomitant radiotherapy for treatment of high-grade glioma. ( Amin, P; Cheston, S; Dhople, A; DiBiase, S; Flannery, T; Meisenberg, B; Patel, A; Patel, S, 2012)
"The authors performed a phase 2 trial of combined protracted daily temozolomide and biweekly bevacizumab for patients with recurrent glioblastoma who had previously received radiation therapy and temozolomide."9.16Bevacizumab and daily temozolomide for recurrent glioblastoma. ( Bailey, L; Coan, A; Desjardins, A; Friedman, HS; Herndon, JE; Marcello, J; Peters, KB; Reardon, DA; Vredenburgh, JJ, 2012)
"Patients with high-grade glioma can be treated with carmustine wafers or following the Stupp protocol."9.16Prognostic factors and survival in a prospective cohort of patients with high-grade glioma treated with carmustine wafers or temozolomide on an intention-to-treat basis. ( Aurrecoechea-Obieta, J; Bilbao-Barandica, G; Canales-Llantada, M; Carbayo-Lozano, G; Catalán-Uribarrena, G; Galbarriatu-Gutiérrez, L; Igartua-Azkune, A; Pomposo-Gaztelu, I; Ruiz de Gopegui-Ruiz, E; Undabeitia-Huertas, J, 2012)
"This phase I trial was designed to determine the recommended phase II dose(s) of everolimus (RAD001) with temozolomide (TMZ) in patients with glioblastoma (GBM)."9.16A phase I study of temozolomide and everolimus (RAD001) in patients with newly diagnosed and progressive glioblastoma either receiving or not receiving enzyme-inducing anticonvulsants: an NCIC CTG study. ( Easaw, J; Eisenhauer, E; Kavan, P; Lwin, Z; Macdonald, D; Macneil, M; Mason, WP; McIntosh, L; Thiessen, B; Urva, S, 2012)
"To report toxicity and overall survival (OS) in patients with newly diagnosed glioblastoma multiforme (GBM) treated with hypofractionated intensity-modulated radiotherapy (hypo-IMRT) with concurrent and adjuvant temozolomide (TMZ)."9.16Phase II trial of hypofractionated IMRT with temozolomide for patients with newly diagnosed glioblastoma multiforme. ( Chen, C; Damek, D; Gaspar, LE; Kavanagh, BD; Lillehei, K; Ney, D; Reddy, K; Stuhr, K; Waziri, A, 2012)
" The primary objectives of this randomized phase 2 trial were to determine the safety and efficacy of cilengitide when combined with radiation and temozolomide for patients with newly diagnosed glioblastoma multiforme and to select a dose for comparative clinical testing."9.16A safety run-in and randomized phase 2 study of cilengitide combined with chemoradiation for newly diagnosed glioblastoma (NABTT 0306). ( Batchelor, T; Brem, S; Fisher, JD; Grossman, SA; Hegi, ME; Lesser, G; Mikkelsen, T; Nabors, LB; Olsen, J; Peereboom, D; Rosenfeld, MR; Ye, X, 2012)
" We did a randomised trial to compare the efficacy and safety of dose-dense temozolomide alone versus radiotherapy alone in elderly patients with anaplastic astrocytoma or glioblastoma."9.16Temozolomide chemotherapy alone versus radiotherapy alone for malignant astrocytoma in the elderly: the NOA-08 randomised, phase 3 trial. ( Braun, C; Combs, SE; Felsberg, J; Ketter, R; Mayer-Steinacker, R; Meisner, C; Meixensberger, J; Nikkhah, G; Papsdorf, K; Platten, M; Reifenberger, G; Sabel, M; Simon, M; Steinbach, JP; Tabatabai, G; Vesper, J; Weller, M; Wick, W, 2012)
"To evaluate the efficacy of adding bevacizumab, a vascular endothelial growth factor (VEGF) inhibitor, and everolimus, a mammalian target of rapamycin (mTOR inhibitor), to standard radiation therapy/temozolomide in the first-line treatment of patients with glioblastoma."9.16Phase II study of concurrent radiation therapy, temozolomide, and bevacizumab followed by bevacizumab/everolimus as first-line treatment for patients with glioblastoma. ( Brinker, BT; Hainsworth, JD; Shepard, GC; Shih, KC; Spigel, DR; Tillinghast, GW, 2012)
"To evaluate the toxicity and maximum tolerated dose (MTD) of arsenic trioxide (ATO) in combination with temozolomide (TMZ) and radiation therapy (RT) in malignant gliomas."9.16Phase I study of arsenic trioxide and temozolomide in combination with radiation therapy in patients with malignant gliomas. ( Chandler, JP; Grimm, SA; Jovanovic, B; Levy, RM; Marymont, M; McCarthy, K; Muro, K; Newman, SB; Raizer, JJ, 2012)
" Both temozolomide and hypofractionated radiotherapy should be considered as standard treatment options in elderly patients with glioblastoma."9.16Temozolomide versus standard 6-week radiotherapy versus hypofractionated radiotherapy in patients older than 60 years with glioblastoma: the Nordic randomised, phase 3 trial. ( Abacioglu, U; Frappaz, D; Grønberg, BH; Hegi, ME; Henriksson, R; Lhermitte, B; Malmström, A; Marosi, C; Rosell, J; Schultz, H; Stupp, R; Tavelin, B, 2012)
"The assessment of the therapeutic response of high-grade gliomas treated with concomitant chemoradiotherapy (CCRT) using temozolomide is difficult because of the frequent occurrence of early imaging changes that are indistinguishable from tumor progression, termed pseudoprogression."9.16Diffusion-weighted MR imaging for the differentiation of true progression from pseudoprogression following concomitant radiotherapy with temozolomide in patients with newly diagnosed high-grade gliomas. ( Choi, SH; Kim, IH; Kim, JH; Kim, TM; Lee, SH; Lee, WJ; Park, CK; Park, SH; Sohn, CH; Yi, KS, 2012)
"A phase I, dose-finding study of vorinostat in combination with temozolomide (TMZ) was conducted to determine the maximum tolerated dose (MTD), safety, and pharmacokinetics in patients with high-grade glioma (HGG)."9.16Phase I study of vorinostat in combination with temozolomide in patients with high-grade gliomas: North American Brain Tumor Consortium Study 04-03. ( Ames, MM; Chang, SM; Cloughesy, TF; Desideri, S; Drappatz, J; Espinoza-Delgado, I; Gilbert, MR; Kuhn, JG; Lamborn, KR; Lassman, AB; Lee, EQ; Lieberman, FS; McGovern, RM; Prados, MD; Puduvalli, VK; Reid, JM; Robins, HI; Wen, PY; Xu, J; Ye, X; Yung, WK, 2012)
"To determine whether the pattern of progressive disease (PD) for glioblastoma multiforme (GBM) patients has changed with the introduction of the current standard of care protocol - postoperative conformal radiotherapy to a dose of 60 Gray in 30 fractions with concurrent low-dose (75-100 mg/m(2) ) temozolomide, followed by six cycles of adjuvant high-dose (150-200 mg/m(2) ) temozolomide - as compared with radiotherapy alone."9.16The addition of temozolomide does not change the pattern of progression of glioblastoma multiforme post-radiotherapy. ( Bressel, M; Gunjur, A; Ryan, G, 2012)
"In the present study we investigated the feasibility and effectiveness of a new biweekly schedule of fotemustine (FTM) in patients with recurrent glioblastoma, after at least one previous treatment."9.15A new schedule of fotemustine in temozolomide-pretreated patients with relapsing glioblastoma. ( Abbruzzese, A; Addeo, R; Caraglia, M; Carraturo, M; Cennamo, G; De Santi, MS; Del Prete, S; Faiola, V; Genovese, M; Montella, L; Parlato, C; Vincenzi, B, 2011)
"To determine the maximal tolerated biologic dose intensification of radiotherapy using fractional dose escalation with temozolomide (TMZ) chemotherapy in patients with newly diagnosed glioblastoma multiforme."9.15Phase I trial of hypofractionated intensity-modulated radiotherapy with temozolomide chemotherapy for patients with newly diagnosed glioblastoma multiforme. ( Chen, C; Damek, D; Gaspar, LE; Kavanagh, BD; Kleinschmidt-DeMasters, BK; Lillehei, K; Robischon, M; Rusthoven, KE; Stuhr, K; Waziri, A, 2011)
"To determine the maximum tolerated dose (MTD) of tipifarnib in combination with conventional radiotherapy for patients with newly diagnosed glioblastoma."9.15A phase I trial of tipifarnib with radiation therapy, with and without temozolomide, for patients with newly diagnosed glioblastoma. ( Abrey, L; Chang, SM; Cloughesy, TF; DeAngelis, LM; Demopoulos, A; Drappatz, J; Fine, HA; Fink, K; Kesari, S; Lamborn, KR; Lassman, AB; Lieberman, FS; Malkin, MG; Mehta, MP; Nghiemphu, PL; Prados, MD; Robins, HI; Torres-Trejo, A; Wen, PY, 2011)
"This open-label, prospective, multicenter single-arm phase II study combined bevacizumab (BV) with radiation therapy (RT) and temozolomide (TMZ) for the treatment of newly diagnosed glioblastoma (GBM)."9.15Phase II study of bevacizumab plus temozolomide during and after radiation therapy for patients with newly diagnosed glioblastoma multiforme. ( Black, K; Cloughesy, T; Elashoff, R; Fehrenbacher, L; Filka, E; Green, RM; Kolevska, T; Lai, A; Liau, LM; Mischel, PS; Nghiemphu, PL; Peak, S; Phuphanich, S; Polikoff, J; Pope, WB; Selch, M; Solis, OE; Spier, CE; Tran, A; Yong, WH, 2011)
"The objective of this prospective, monocentric phase-II pilot study was to evaluate toxicity and efficacy of neoadjuvant temozolomide (TMZ) and 13-cis retinoic acid (13-cRA) treatment in patients with newly diagnosed anaplastic gliomas after total or subtotal tumor resection."9.15Temozolomide and 13-cis retinoic acid in patients with anaplastic gliomas: a prospective single-arm monocentric phase-II study (RNOP-05). ( Bogdahn, U; Brawanski, A; Grauer, O; Hartmann, C; Hau, P; Pascher, C; Pietsch, T; Proescholdt, M; Weller, M; Wick, W; Zeman, F, 2011)
"To analyse patterns of failure in patients with glioblastoma multiforme treated with concurrent radiation and temozolomide."9.15Patterns of failure for glioblastoma multiforme following concurrent radiation and temozolomide. ( Burnett Iii, OL; Dobelbower, MC; Fiveash, JB; Hyatt, MD; Markert, JM; Nabors, LB; Nordal, RA, 2011)
"This study compared the central nervous system (CNS) metastasis incidence between a temozolomide- and a dacarbazine-based regimen in untreated stage IV melanoma patients."9.15Central nervous system failure in melanoma patients: results of a randomised, multicentre phase 3 study of temozolomide- and dacarbazine- based regimens. ( Brugnara, S; Chiarion-Sileni, V; Colucci, G; De Salvo, GL; Del Bianco, P; Guida, M; Pigozzo, J; Ridolfi, L; Ridolfi, R; Romanini, A, 2011)
"Concurrent and post-radiotherapy temozolomide (T) significantly improves survival in patient with newly diagnosed glioblastoma multiforme."9.15Phase 2 trial of temozolomide and pegylated liposomal doxorubicin in the treatment of patients with glioblastoma multiforme following concurrent radiotherapy and chemotherapy. ( Ananda, S; Brown, C; Cher, L; Dowling, A; Nowak, AK; Rosenthal, MA; Simes, J, 2011)
"This analysis was performed to assess whether antiepileptic drugs (AEDs) modulate the effectiveness of temozolomide radiochemotherapy in patients with newly diagnosed glioblastoma."9.15Prolonged survival with valproic acid use in the EORTC/NCIC temozolomide trial for glioblastoma. ( Belanger, K; Bogdahn, U; Brandes, AA; Cairncross, JG; Forsyth, P; Gorlia, T; Lacombe, D; Macdonald, DR; Mason, W; Mirimanoff, RO; Rossetti, AO; Stupp, R; van den Bent, MJ; Vecht, CJ; Weller, M, 2011)
"This open-label, single-arm, phase II study combined enzastaurin with temozolomide plus radiation therapy (RT) to treat glioblastoma multiforme (GBM) and gliosarcoma."9.15Phase II and pharmacogenomics study of enzastaurin plus temozolomide during and following radiation therapy in patients with newly diagnosed glioblastoma multiforme and gliosarcoma. ( Butowski, N; Chang, SM; Clarke, J; Costa, BM; Costello, JF; Hristova-Kazmierski, M; Hsieh, E; Lamborn, KR; Nicol, SJ; Nicole, A; Parvataneni, R; Pieper, R; Polley, MY; Prados, MD; Reis, RM; Sneed, PK; Thornton, DE; Vandenberg, S, 2011)
"The primary objectives of this phase II study were to evaluate the use of preirradiation temozolomide followed by concurrent temozolomide and radiotherapy (RT) in patients with newly diagnosed anaplastic oligodendroglioma (AO) and mixed anaplastic oligoastrocytoma (MOA)."9.14Phase II trial of preirradiation and concurrent temozolomide in patients with newly diagnosed anaplastic oligodendrogliomas and mixed anaplastic oligoastrocytomas: RTOG BR0131. ( Berkey, B; Biggs, C; Blumenthal, DT; Brown, P; Giannini, C; Herman, J; Jenkins, R; Macdonald, D; Mehta, M; Peereboom, D; Schultz, C; Suh, JH; Vogelbaum, MA, 2009)
"To determine whether increased uptake on 11C-methionine-PET (MET-PET) imaging obtained before radiation therapy and temozolomide is associated with the site of subsequent failure in newly diagnosed glioblastoma multiforme (GBM)."9.14Association of 11C-methionine PET uptake with site of failure after concurrent temozolomide and radiation for primary glioblastoma multiforme. ( Cao, Y; Gomez-Hassan, D; Hayman, J; Junck, L; Lawrence, TS; Lee, IH; Piert, M; Rogers, L; Ten Haken, RK; Tsien, C, 2009)
"In a search for more effective combination chemotherapy for the treatment of metastatic melanoma, we conducted a phase I trial of a novel combination of docetaxel, temozolomide, and cisplatin."9.14Phase I study of the combination of docetaxel, temozolomide and cisplatin in patients with metastatic melanoma. ( Bedikian, AY; Camacho, LH; Frost, AM; Hernandez, IM; Hwu, P; Hwu, WJ; Jack, MA; Kim, KB; Ng, C; Papadopoulos, NE, 2009)
"This open-label, prospective, single-arm, phase II study combined erlotinib with radiation therapy (XRT) and temozolomide to treat glioblastoma multiforme (GBM) and gliosarcoma."9.14Phase II study of erlotinib plus temozolomide during and after radiation therapy in patients with newly diagnosed glioblastoma multiforme or gliosarcoma. ( Ayers-Ringler, J; Berger, MS; Butowski, N; Carliner, H; Chang, SM; DeBoer, R; Fedoroff, A; Haas-Kogan, DA; James, CD; Kabuubi, P; Lamborn, KR; McDermott, MW; Page, M; Parsa, AT; Parvataneni, R; Prados, MD; Rabbitt, J; Sneed, PK; Stokoe, D; Vandenberg, S, 2009)
"Patients with newly diagnosed oligodendroglioma or oligoastrocytoma with a MIB-1 index of >5% or recurrent low-grade gliomas received temozolomide (75 mg/m(2)/day in 11-week cycles of 7 weeks on/4 weeks off)."9.14Phase II study of protracted daily temozolomide for low-grade gliomas in adults. ( Black, PM; Bradshaw, J; Ciampa, A; Doherty, L; Drappatz, J; Kesari, S; LaFrankie, D; Levy, B; Ligon, KL; Macklin, EA; Muzikansky, A; Norden, AD; Radakovic, G; Ramakrishna, N; Santagata, S; Schiff, D; Wen, PY, 2009)
"Standardized salvage treatment has not yet proved effective in glioblastoma multiforme (GBM) patients who receive prior standard radiotherapy plus concomitant and adjuvant temozolomide."9.14Fotemustine as second-line treatment for recurrent or progressive glioblastoma after concomitant and/or adjuvant temozolomide: a phase II trial of Gruppo Italiano Cooperativo di Neuro-Oncologia (GICNO). ( Amistà, P; Bianchini, C; Blatt, V; Brandes, AA; Ermani, M; Faedi, M; Franceschi, E; Gardiman, M; Labianca, R; Reni, M; Santoro, A; Tosoni, A, 2009)
"This phase II trial was designed to define the role of O(6)-benzylguanine (O(6)-BG) in restoring temozolomide sensitivity in patients with recurrent or progressive, temozolomide-resistant malignant glioma and to evaluate the safety of administering O(6)-BG in combination with temozolomide."9.14Phase II trial of temozolomide plus o6-benzylguanine in adults with recurrent, temozolomide-resistant malignant glioma. ( Bigner, DD; Desjardins, A; Friedman, AH; Friedman, HS; Gururangan, S; Herndon, JE; Jiang, SX; McLendon, RE; Quinn, JA; Reardon, DA; Rich, JN; Sampson, JH; Vredenburgh, JJ; Walker, A, 2009)
"In 2004, a randomised phase III trial by the European Organisation for Research and Treatment of Cancer (EORTC) and National Cancer Institute of Canada Clinical Trials Group (NCIC) reported improved median and 2-year survival for patients with glioblastoma treated with concomitant and adjuvant temozolomide and radiotherapy."9.14Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial. ( Allgeier, A; Belanger, K; Brandes, AA; Cairncross, JG; Eisenhauer, E; Fisher, B; Gijtenbeek, J; Gorlia, T; Hau, P; Hegi, ME; Janzer, RC; Lacombe, D; Ludwin, SK; Marosi, C; Mason, WP; Mirimanoff, RO; Mokhtari, K; Stupp, R; Taphoorn, MJ; van den Bent, MJ; Vecht, CJ; Villa, S; Weller, M; Wesseling, P, 2009)
"This phase I clinical trial conducted with patients who had recurrent or progressive malignant glioma (MG) was designed to determine the maximum tolerated dose (MTD) and toxicity of three different 5-day dosing regimens of temozolomide (TMZ) in combination with O(6)-benzylguanine (O(6)-BG)."9.14Phase I trial of temozolomide plus O6-benzylguanine 5-day regimen with recurrent malignant glioma. ( Bigner, DD; Desjardins, A; Friedman, AH; Friedman, HS; Gururangan, S; Herndon, JE; Jiang, SX; McLendon, RE; Quinn, JA; Reardon, DA; Rich, JN; Sampson, JH; Vredenburgh, JJ; Walker, A, 2009)
" We investigated the time course of tumor metabolism in low-grade gliomas (LGG) during temozolomide chemotherapy, and compared metabolic responses as measured with positron emission tomography (PET) with volume responses as revealed by magnetic resonance imaging (MR)."9.14Early metabolic responses in temozolomide treated low-grade glioma patients. ( Bärtschi, E; Bruehlmeier, M; Buettner, UW; Hefti, M; Hofer, S; Roelcke, U; Uhlmann, C; Wyss, M, 2009)
"Alternative dosing schedules of temozolomide may improve survival in patients with newly diagnosed glioblastoma (GBM) by increasing the therapeutic index, overcoming common mechanisms of temozolomide resistance, or both."9.14Randomized phase II trial of chemoradiotherapy followed by either dose-dense or metronomic temozolomide for newly diagnosed glioblastoma. ( Abrey, LE; Clarke, JL; DeAngelis, LM; Gavrilovic, I; Hormigo, A; Iwamoto, FM; Karimi, S; Lassman, AB; Nolan, CP; Panageas, K; Sul, J, 2009)
"This phase II trial evaluated efficacy and safety of temozolomide (TMZ) in combination with irinotecan (CPT-11) before radiotherapy in patients with newly diagnosed glioblastoma multiforme (GBM)."9.14Phase II trial of temozolomide (TMZ) plus irinotecan (CPT-11) in adults with newly diagnosed glioblastoma multiforme before radiotherapy. ( Desjardins, A; Friedman, AH; Friedman, HS; Herndon, JE; Jiang, SX; McLendon, RE; Quinn, JA; Reardon, DA; Sampson, JH; Vredenburgh, JJ, 2009)
"This trial was designed to estimate overall survival in adults with newly diagnosed glioblastoma treated with talampanel in addition to standard radiation (RT) and temozolomide (TMZ)."9.14Talampanel with standard radiation and temozolomide in patients with newly diagnosed glioblastoma: a multicenter phase II trial. ( Batchelor, T; Chamberlain, M; Desideri, S; Fine, HA; Fisher, J; Grossman, SA; Mikkelsen, T; Piantadosi, S; Ye, X, 2009)
"To present outcome data in a prospective study of radiotherapy (RT) with concurrent and adjuvant temozolomide (TMZ) in children with diffuse intrinsic pontine gliomas (DIPGs)."9.14Prospective evaluation of radiotherapy with concurrent and adjuvant temozolomide in children with newly diagnosed diffuse intrinsic pontine glioma. ( Arora, B; Dutta, D; Gupta, T; Jalali, R; Kurkure, P; Munshi, A; Raut, N; Sarin, R, 2010)
"This multicenter phase II study conducted by the Spanish Neuro-Oncology Group evaluated the activity of an extended, dose-dense temozolomide regimen in patients with temozolomide-refractory malignant glioma."9.14Extended-schedule dose-dense temozolomide in refractory gliomas. ( Balaña, C; Berrocal, A; Gallego, O; Garcia Lopez, J; Gil, M; Iglesias, L; Perez Segura, P; Reynes, G; Rodríguez, J; Yaya, R, 2010)
"Because of the poor outcomes for patients with recurrent glioblastoma multiforme (GBM), and some laboratory and clinical evidence of efficacy using interferon in GBM, we assessed the toxicity and efficacy of temozolomide (TMZ) combined with either short-acting (IFN) or long-acting (pegylated) interferon alpha2b (PEG) in two single-arm phase II studies, and compared the results to 6-month progression-free survival (PFS-6) data from historical controls."9.14Two phase II trials of temozolomide with interferon-alpha2b (pegylated and non-pegylated) in patients with recurrent glioblastoma multiforme. ( Alfred Yung, WK; Conrad, CA; Gilbert, MR; Groves, MD; Hess, KR; Hunter, K; Levin, VA; Liu, VH; Meyers, C; Puduvalli, VK, 2009)
"To determine the maximum tolerated dose (MTD) of fractionated intensity-modulated radiotherapy (IMRT) with temozolomide (TMZ) in patients with glioblastoma."9.14A phase I dose-escalation study (ISIDE-BT-1) of accelerated IMRT with temozolomide in patients with glioblastoma. ( Balducci, M; Calista, F; Cantore, GP; Cellini, N; Cilla, S; Deodato, F; Digesù, C; Esposito, V; Ferro, M; Ianiri, M; Macchia, G; Morganti, AG; Piermattei, A; Romanelli, P; Salvati, M; Valentini, V, 2010)
"This alternating weekly, dose-dense temozolomide regimen was well tolerated and clinically active in heavily pretreated patients with brain metastases, particularly in patients with melanoma."9.14Dose-dense temozolomide regimen for the treatment of brain metastases from melanoma, breast cancer, or lung cancer not amenable to surgery or radiosurgery: a multicenter phase II study. ( Bajetta, E; Cascinu, S; Crinò, L; Danova, M; Del Prete, S; Salvagni, S; Schiavetto, I; Siena, S; Vitali, M, 2010)
"To evaluate the toxicity and efficacy of chemoradiotherapy with temozolomide (TMZ) administered in an intensified 1-week on/1-week off schedule plus indomethacin in patients with newly diagnosed glioblastoma."9.14Chemoradiotherapy of newly diagnosed glioblastoma with intensified temozolomide. ( Bähr, O; Bamberg, M; Gorlia, T; Hartmann, C; Herrlinger, U; Meyermann, R; Tatagiba, M; von Deimling, A; Weiler, M; Weller, M; Wick, W; Wiewrodt, D, 2010)
"Heavily pre-treated patients with temozolomide-refractory high-grade malignant glioma received cisplatin at a dose of 75 mg/m(2) on day 1 and temozolomide at a dose of 150 mg/m(2) on days 1 to 5 every 21 days until progression or major toxicity."9.14A phase II study of cisplatin and temozolomide in heavily pre-treated patients with temozolomide-refractory high-grade malignant glioma. ( Della Puppa, A; Lombardi, G; Pastorelli, D; Rotilio, A; Scienza, R; Zustovich, F, 2009)
"We retrospectively investigated the correlation of IDH1 and IDH2 mutations with overall survival and response to temozolomide in a cohort of patients with dedifferentiated low-grade astrocytomas treated with temozolomide at the time of progression after radiotherapy."9.14IDH1 mutations in low-grade astrocytomas predict survival but not response to temozolomide. ( Boogerd, W; Bromberg, JE; Dinjens, WN; Dubbink, HJ; Gijtenbeek, JM; Groenendijk, FH; Kros, JM; Postma, TJ; Smitt, PA; Taal, W; van den Bent, MJ; van Heuvel, I; van Marion, R; Zonnenberg, BA; Zonnenberg, CB, 2009)
"To investigate the efficacy and safety of temozolomide (TMZ) and lomustine (CCNU) in malignant brain gliomas."9.14[A multicenter randomized controlled study of temozolomide in 97 patients with malignant brain glioma]. ( Chang, Y; Fu, Z; Liu, XM; Liu, XY; Qian, ZZ; Wang, HQ; Yang, SY; Yu, H, 2009)
"We conducted a phase I study to determine the safety and recommended phase II dose of enzastaurin (oral inhibitor of the protein kinase C-beta [PKCbeta] and the PI3K/AKT pathways) when given in combination with radiation therapy (RT) plus temozolomide to patients with newly diagnosed glioblastoma multiforme or gliosarcoma."9.14Enzastaurin plus temozolomide with radiation therapy in glioblastoma multiforme: a phase I study. ( Butowski, N; Chang, SM; Hristova-Kazmierski, M; Lamborn, KR; Musib, L; Nicol, SJ; Parvataneni, R; Polley, MY; Prados, MD; Thornton, DE, 2010)
"We assessed six-month progression-free survival (PFS) as an alternative primary efficacy endpoint to overall survival in newly diagnosed glioblastoma multiforme (GBM) patients receiving temozolomide (TMZ)."9.14Six-month progression-free survival as an alternative primary efficacy endpoint to overall survival in newly diagnosed glioblastoma patients receiving temozolomide. ( Butowski, N; Chang, SM; Clarke, JL; Lamborn, KR; Polley, MY; Prados, M, 2010)
"To determine the maximum tolerated dose of ABT-510, a thrombospondin-1 mimetic drug with antiangiogenic properties, when used concurrently with temozolomide and radiotherapy in patients with newly diagnosed glioblastoma."9.14A phase 1 trial of ABT-510 concurrent with standard chemoradiation for patients with newly diagnosed glioblastoma. ( Fathallah-Shaykh, HM; Fiveash, JB; Gillespie, GY; Gladson, CL; Huang, Z; Johnson, MJ; Kekan, MS; Kuo, H; Markert, JM; Meleth, S; Nabors, LB, 2010)
"PURPOSE Concomitant temozolomide (TMZ)/radiotherapy followed by adjuvant TMZ has increased survival in patients with glioblastoma multiforme (GBM)."9.14Phase II trial of continuous dose-intense temozolomide in recurrent malignant glioma: RESCUE study. ( Bélanger, K; Easaw, J; Eisenstat, DD; Forsyth, P; Fulton, D; Kavan, P; Kirby, S; Macdonald, DR; Mason, WP; Perry, JR; Pouliot, JF; Shields, C; Thiessen, B, 2010)
"Twenty-two patients with newly diagnosed malignant glioma who received standard radiation/temozolomide therapy were recruited for the study."9.14Effects of concomitant temozolomide and radiation therapies on WT1-specific T-cells in malignant glioma. ( Chiba, Y; Hashimoto, N; Hosen, N; Kagawa, N; Kinoshita, M; Murao, A; Nishida, S; Oji, Y; Oka, Y; Sugiyama, H; Tsuboi, A; Yoshimine, T, 2010)
"The aim of this clinical trial was to investigate safety and efficacy when combining cetuximab with bevacizumab and irinotecan in patients with recurrent primary glioblastoma multiforme (GBM)."9.14Cetuximab, bevacizumab, and irinotecan for patients with primary glioblastoma and progression after radiation therapy and temozolomide: a phase II trial. ( Broholm, H; Hansen, S; Hasselbalch, B; Holmberg, M; Kosteljanetz, M; Lassen, U; Poulsen, HS; Stockhausen, MT; Sørensen, M, 2010)
"Compared with historical controls, the addition of concomitant and adjuvant cilengitide to standard chemoradiotherapy demonstrated promising activity in patients with glioblastoma with MGMT promoter methylation."9.14Phase I/IIa study of cilengitide and temozolomide with concomitant radiotherapy followed by cilengitide and temozolomide maintenance therapy in patients with newly diagnosed glioblastoma. ( Clement, PM; Dietrich, PY; Diserens, AC; Goldbrunner, R; Grabenbauer, GG; Hegi, ME; Hermisson, M; Hicking, C; Krueger, S; Neyns, B; Ochsenbein, AF; Pica, A; Picard, M; Pietsch, T; Schlegel, U; Simon, M; Stupp, R; Tonn, JC; Weller, M, 2010)
"The current study was conducted to evaluate the efficacy of sorafenib, an oral vascular endothelial growth factor receptor tyrosine kinase inhibitor, when added to standard radiotherapy and temozolomide in the first-line treatment of patients with glioblastoma multiforme."9.14Concurrent radiotherapy and temozolomide followed by temozolomide and sorafenib in the first-line treatment of patients with glioblastoma multiforme. ( Clark, BL; Ervin, T; Friedman, E; Hainsworth, JD; Lamar, RE; Murphy, PB; Priego, V, 2010)
"The objectives of this study were to determine the safety and efficacy of polyinosinic-polycytidylic acid stabilized with poly-l-lysine and carboxymethylcellulose (poly-ICLC) when added to radiation and temozolomide (TMZ) in adults with newly diagnosed glioblastoma (GB)."9.14A multi-institution phase II study of poly-ICLC and radiotherapy with concurrent and adjuvant temozolomide in adults with newly diagnosed glioblastoma. ( Batchelor, TT; Chamberlain, MC; Desideri, S; Grossman, SA; Lesser, GJ; Peereboom, DM; Rosenfeld, MR; Salazar, AM; Ye, X, 2010)
"Treatment standard for patients with primary glioblastoma (GBM) is combined radiochemotherapy with temozolomide (TMZ)."9.14Randomized phase II study evaluating a carbon ion boost applied after combined radiochemotherapy with temozolomide versus a proton boost after radiochemotherapy with temozolomide in patients with primary glioblastoma: the CLEOPATRA trial. ( Combs, SE; Debus, J; Haberer, T; Habermehl, D; Haselmann, R; Jäkel, O; Kieser, M; Nikoghosyan, A; Rieken, S; Unterberg, A; Wick, W, 2010)
"To evaluate efficacy and safety of fotemustine chemotherapy in temozolomide (TMZ) pretreated adults with recurrent glioblastoma multiforme (GBM)."9.13Second-line chemotherapy with fotemustine in temozolomide-pretreated patients with relapsing glioblastoma: a single institution experience. ( Ammannati, F; Biti, G; Bordi, L; Borghesi, S; Detti, B; Iannalfi, A; Leonulli, BG; Martinelli, F; Meattini, I; Sardaro, A; Scoccianti, S, 2008)
"We performed a new phase II trial enrolling patients with newly diagnosed high-grade glioma (HGG) to test the efficacy of a weekly alternating temozolomide (TMZ) schedule after surgery and concomitant chemoradiotherapy."9.13Dose-intensity temozolomide after concurrent chemoradiotherapy in operated high-grade gliomas. ( D'Amico, A; Dall'oglio, S; Gabbani, M; Maluta, S; Pasini, F; Passarin, MG; Pioli, F; Talacchi, A; Turazzi, S, 2008)
"The combination of temozolomide (TMZ) and thalidomide was reported to produce a high response rate, including shrinkage of brain metastases, in patients with metastatic melanoma."9.13Temozolomide, thalidomide, and whole brain radiation therapy for patients with brain metastasis from metastatic melanoma: a phase II Cytokine Working Group study. ( Agarwala, S; Atkins, MB; Clark, JI; Curti, B; Dutcher, JP; Ernstoff, MS; Lawson, D; Logan, T; Margolin, KA; Sosman, JA; Weiss, G, 2008)
"A multicenter phase I clinical trial, namely, Integrated Japanese Multicenter Clinical Trial: A Phase I Study of Interferon-beta and Temozolomide for Glioma in Combination with Radiotherapy (INTEGRA Study), is being conducted for patients with high-grade glioma in order to evaluate the safety, feasibility and preliminary clinical effectiveness of the combination of interferon-beta and temozolomide."9.13A multicenter phase I trial of interferon-beta and temozolomide combination therapy for high-grade gliomas (INTEGRA Study). ( Aoki, T; Hashimoto, N; Kayama, T; Kurisu, K; Natsume, A; Nishikawa, R; Ogura, M; Takahashi, H; Wakabayashi, T; Yoshida, J; Yoshimine, T, 2008)
"To evaluate the efficacy of simultaneous postoperative temozolomide radiochemotherapy in glioblastoma patients."9.13Randomized study of postoperative radiotherapy and simultaneous temozolomide without adjuvant chemotherapy for glioblastoma. ( Becker, G; Borberg, SK; Fischedick, AR; Frommolt, P; Grauthoff, H; Herfarth, K; Kocher, M; Müller, RP; Niewald, M; Rühl, U; Staar, S; Steingräber, M; Stuschke, M, 2008)
"This is a phase-I study of gefitinib in combination with temozolomide in patients with gliomas."9.13Phase-1 trial of gefitinib and temozolomide in patients with malignant glioma: a North American brain tumor consortium study. ( Chang, S; Cloughesy, T; Dancey, J; Fink, K; Junck, L; Kuhn, J; Prados, MD; Robins, HI; Wen, PY; Yung, WK, 2008)
"The study aimed to compare the cost-effectiveness of concomitant and adjuvant temozolomide (TMZ) for the treatment of newly diagnosed glioblastoma multiforme versus initial radiotherapy alone from a public health care perspective."9.13Cost-effectiveness of temozolomide for the treatment of newly diagnosed glioblastoma multiforme: a report from the EORTC 26981/22981 NCI-C CE3 Intergroup Study. ( Al, MJ; Crott, R; Gorlia, T; Jin Seung, S; Lamers, LM; Mittmann, N; Stupp, R; Uyl-de Groot, CA; van den Bent, MJ; Wasserfallen, JB, 2008)
"Twice-daily dosing may enhance the efficacy of temozolomide in the treatment of recurrent gliomas without increasing toxicity."9.13Multi-institutional phase II study of temozolomide administered twice daily in the treatment of recurrent high-grade gliomas. ( Alavi, J; Balmaceda, C; Chen, J; Cheung, YK; Fine, RL; Fisher, PG; Pannullo, S; Peereboom, D; Sisti, M, 2008)
"To evaluate toxicity and outcomes in patients with primary glioblastoma (GB) treated with postoperative radiochemotherapy (RCHT) with temozolomide (TMZ) comparing two dose regimens."9.13Radiochemotherapy in patients with primary glioblastoma comparing two temozolomide dose regimens. ( Bischof, M; Combs, SE; Debus, J; Edler, L; Rausch, R; Schulz-Ertner, D; Wagner, F; Wagner, J; Welzel, T; Zabel-du Bois, A, 2008)
"We conducted a single institution phase II trial to evaluate the tolerability and effectiveness of therapy with arsenic trioxide (ATO) and ascorbic acid (AA) with temozolomide (TMZ) in patients with advanced melanoma."9.13Phase II trial of arsenic trioxide and ascorbic acid with temozolomide in patients with metastatic melanoma with or without central nervous system metastases. ( Bael, TE; Gollob, JA; Peterson, BL, 2008)
"To assess interim safety and tolerability of a 10-patient, Phase II pilot study using bevacizumab (BV) in combination with temozolomide (TMZ) and regional radiation therapy (RT) in the up-front treatment of patients with newly diagnosed glioblastoma."9.13Phase II pilot study of bevacizumab in combination with temozolomide and regional radiation therapy for up-front treatment of patients with newly diagnosed glioblastoma multiforme: interim analysis of safety and tolerability. ( Bergsneider, M; Cloughesy, T; Filka, E; Graham, C; Lai, A; Liau, LM; McGibbon, B; Mischel, P; Nghiemphu, PL; Pope, W; Selch, M; Yong, WH, 2008)
"We determined the maximum tolerated dose (MTD) and dose-limiting toxicity (DLT) of imatinib mesylate, an inhibitor of the receptor tyrosine kinases platelet-derived growth factor receptor (PDGFR), the proto-oncogene product c-kit, and the fusion protein Bcr-Abl, when administered for 8 days in combination with temozolomide (TMZ) to malignant glioma (MG) patients."9.13Safety and pharmacokinetics of dose-intensive imatinib mesylate plus temozolomide: phase 1 trial in adults with malignant glioma. ( Desjardins, A; Egorin, MJ; Friedman, AH; Friedman, HS; Gururangan, S; Herndon, JE; Lagattuta, TF; McLendon, R; Quinn, JA; Reardon, DA; Rich, JN; Salvado, AJ; Sathornsumetee, S; Vredenburgh, JJ, 2008)
"The primary objective of this prospective phase 2 study of CPT-11 in adult patients with recurrent temozolomide-refractory anaplastic astrocytoma (AA) was to evaluate 6-month progression-free survival (PFS)."9.13Salvage chemotherapy with CPT-11 for recurrent temozolomide-refractory anaplastic astrocytoma. ( Blumenthal, DT; Chamberlain, MC; Glantz, MJ; Wei-Tsao, DD, 2008)
"We conducted a phase II study of the combination of temozolomide and angiogenesis inhibitors for treating adult patients with newly diagnosed glioblastoma."9.13Phase II study of temozolomide, thalidomide, and celecoxib for newly diagnosed glioblastoma in adults. ( Batchelor, TT; Black, PM; Ciampa, A; Doherty, L; Drappatz, J; Folkman, J; Gigas, DC; Henson, JW; Kesari, S; Kieran, M; Laforme, A; Ligon, KL; Longtine, JA; Muzikansky, A; Ramakrishna, N; Schiff, D; Weaver, S; Wen, PY, 2008)
"The aim of the present study was to determine in patients with progressive or recurrent low grade gliomas, the response rate and toxicity incurred by a continued schedule of temozolomide chemotherapy administered before radiation therapy, and to explore correlations between response and survival with 1p/19q deletions and MGMT promoter methylation status."9.13Temozolomide three weeks on and one week off as first line therapy for patients with recurrent or progressive low grade gliomas. ( Bertorelle, R; Blatt, V; Bonaldi, L; Brandes, AA; Ermani, M; Franceschi, E; Tosoni, A, 2008)
"To evaluate outcome after fractionated stereotactic radiotherapy (FSRT) and concomitant daily temozolomide (TMZ) in patients with recurrent gliomas."9.13Radiochemotherapy with temozolomide as re-irradiation using high precision fractionated stereotactic radiotherapy (FSRT) in patients with recurrent gliomas. ( Bischof, M; Combs, SE; Debus, J; Hof, H; Oertel, S; Schulz-Ertner, D; Welzel, T, 2008)
"A Phase II study of CPT-11 in adults with recurrent, temozolomide (TMZ)-refractory, 1p19q co-deleted, anaplastic oligodendroglioma (AO) with a primary objective of determining 6-month progression free survival (PFS)."9.13CPT-11 for recurrent temozolomide-refractory 1p19q co-deleted anaplastic oligodendroglioma. ( Chamberlain, MC; Glantz, MJ, 2008)
"A phase I trial was conducted to determine the maximum tolerated dose (MTD) of temozolomide given in combination with lomustine in newly diagnosed pediatric patients with high-grade gliomas."9.13A phase I trial of temozolomide and lomustine in newly diagnosed high-grade gliomas of childhood. ( Adamson, PC; Blaney, SM; Flom, L; Ingle, AM; Jakacki, RI; Pollack, IF; Prados, MD; Timmerman, R; Yates, A; Zhou, T, 2008)
"We performed a Cochrane Review to examine studies using different techniques to measure MGMT and predict survival in glioblastoma patients treated with temozolomide."9.12MGMT promoter methylation testing to predict overall survival in people with glioblastoma treated with temozolomide: a comprehensive meta-analysis based on a Cochrane Systematic Review. ( Brandner, S; Cheng, HY; Dawson, S; Faulkner, CL; Higgins, JPT; Jefferies, S; Kelly, C; Kurian, KM; McAleenan, A; Schmidt, L; Spiga, F; Wragg, C, 2021)
"Recent developments in pharmacogenomics have created opportunities for predicting temozolomide response in gliomas."9.12Comprehensive pharmacogenomics characterization of temozolomide response in gliomas. ( Long, J; Tong, S; Wang, B; Wang, Y; Wu, J; Zhong, P, 2021)
"We searched Medline and Embase (Jan 1994-Jan 2021) for studies evaluating the effect of temozolomide monotherapy on cell viability of at least one malignant glioma cell line."9.12Temozolomide sensitivity of malignant glioma cell lines - a systematic review assessing consistencies between in vitro studies. ( Brennan, PM; Bruce, M; Hannan, CJ; Poon, MTC; Simpson, JE, 2021)
"To determine which method for assessing MGMT methylation status best predicts overall survival in people diagnosed with glioblastoma who are treated with temozolomide."9.12Prognostic value of test(s) for O6-methylguanine-DNA methyltransferase (MGMT) promoter methylation for predicting overall survival in people with glioblastoma treated with temozolomide. ( Brandner, S; Cheng, HY; Dawson, S; Faulkner, CL; Higgins, JPT; Howell, A; Jefferies, S; Kelly, C; Kernohan, A; Kurian, KM; McAleenan, A; Robinson, T; Schmidt, L; Spiga, F; Vale, L; Wragg, C, 2021)
"In this review, we discuss the use of the alkylating agent temozolomide (TMZ) in the treatment of IDH-mutant gliomas."9.12From Laboratory Studies to Clinical Trials: Temozolomide Use in IDH-Mutant Gliomas. ( Sun, X; Turcan, S, 2021)
"(1) Background: Studies in elderly patients over the age of 65 with glioblastoma have shown survival benefits of short-course radiation therapy with concurrent and adjuvant temozolomide, making it the standard of care adopted at Juravinski Cancer Center."9.12Outcomes in Elderly Patients with Glioblastoma Multiforme Treated with Short-Course Radiation Alone Compared to Short-Course Radiation and Concurrent and Adjuvant Temozolomide Based on Performance Status and Extent of Resection. ( Greenspoon, JN; Mir, T; Pond, G, 2021)
"The objective of the study was to evaluate the efficacy and toxicity of Temozolomide (TMZ) administered for 5 consecutive days in three daily dosing in children with recurrent or refractory high-grade glioma."9.12Phase II trial of temozolomide in children with recurrent high-grade glioma. ( Abate, ME; Attinà, G; Caldarelli, M; Cefalo, G; Clerico, A; Colosimo, C; Di Rocco, C; Garré, ML; Lazzareschi, I; Madon, E; Massimino, M; Maurizi, P; Mazzarella, G; Riccardi, R; Ridola, V; Ruggiero, A; Sandri, A, 2006)
"A prospective Phase II study of cyclophosphamide (CYC) was conducted in adult patients with recurrent temozolomide-refractory anaplastic astrocytoma (AA) with a primary objective of evaluating 6-month progression-free survival (PFS)."9.12Salvage chemotherapy with cyclophosphamide for recurrent temozolomide-refractory anaplastic astrocytoma. ( Chamberlain, MC; Groshen, S; Tsao-Wei, DD, 2006)
"Temozolomide (TMZ) a recent, oral, second generation alkylating agent is a chemotherapeutic with demonstrated efficacy for the treatment of high-grade gliomas."9.12Surgery, radiotherapy and temozolomide in treating high-grade gliomas. ( Barbarisi, M; Moraci, A; Moraci, M; Parlato, C, 2006)
"Our objective was to evaluate the toxicity and antitumor efficacy of concurrent biochemotherapy in metastatic melanoma patients and the effectiveness of adding temozolomide to protect the brain from metastases."9.12A biochemotherapy regimen with concurrent administration of cisplatin, vinblastine, temozolomide (Temodal), interferon-alfa and interleukin-2 for metastatic melanoma: a phase II study. ( Asna, N; Inbar, MJ; Metser, U; Ron, IG; Ryvo, L; Safra, T; Sapir, EE; Sarid, D; Schneebaum, S, 2006)
"The purpose of this study was to define the maximum tolerated dose of erlotinib and characterize its pharmaco-kinetics and safety profile, alone and with temozolomide, with and without enzyme-inducing antiepileptic drugs (EIAEDs), in patients with malignant gliomas."9.12Phase 1 study of erlotinib HCl alone and combined with temozolomide in patients with stable or recurrent malignant glioma. ( Burton, E; Butowski, N; Chang, S; Fedoroff, A; Kapadia, A; Kelley, SK; Lamborn, KR; Malec, M; Page, MS; Prados, MD; Rabbitt, J; Xie, D, 2006)
"Since anaplastic gliomas (AG) depend on matrix metalloproteinases for tumor cell invasion and angiogenesis, we undertook this phase II study to evaluate the matrix metalloproteinase inhibitor marimastat (MT), combined with the alkylator temozolomide (TMZ) in patients with recurrent AG, looking for improved outcomes."9.12Phase II trial of temozolomide plus marimastat for recurrent anaplastic gliomas: a relationship among efficacy, joint toxicity and anticonvulsant status. ( Aldape, KD; Conrad, CA; Gilbert, MR; Groves, MD; Hess, KR; Jaeckle, K; Levin, VA; Liu, V; Puduvalli, VK; Yung, WK, 2006)
"The implementation of combined radiochemotherapy (RCHT) with temozolomide (TMZ) has lead to a significant increase in overall survival times in patients with Glioblastoma multiforme (GBM), however, outcome still remains unsatisfactory."9.12Treatment of primary glioblastoma multiforme with cetuximab, radiotherapy and temozolomide (GERT)--phase I/II trial: study protocol. ( Combs, SE; Debus, J; Edler, L; Haselmann, R; Heeger, S; Schulz-Ertner, D, 2006)
"The European Organisation for Research and Treatment of Cancer and National Cancer Institute of Canada trial on temozolomide (TMZ) and radiotherapy (RT) in glioblastoma (GBM) has demonstrated that the combination of TMZ and RT conferred a significant and meaningful survival advantage compared with RT alone."9.12Radiotherapy and temozolomide for newly diagnosed glioblastoma: recursive partitioning analysis of the EORTC 26981/22981-NCIC CE3 phase III randomized trial. ( Allgeier, A; Brandes, AA; Cairncross, G; Curschmann, J; Fisher, B; Gorlia, T; Kortmann, RD; Lacombe, D; Mason, W; Mirimanoff, RO; Reni, M; Stupp, R; Van den Bent, MJ; Villa, S, 2006)
"To date, no data are available on the relationship between 1p/19q deletions and the response to temozolomide (TMZ) in primary anaplastic oligodendroglioma (AO) and anaplastic oligoastrocytoma (AOA) recurrent after surgery and standard radiotherapy."9.12Correlations between O6-methylguanine DNA methyltransferase promoter methylation status, 1p and 19q deletions, and response to temozolomide in anaplastic and recurrent oligodendroglioma: a prospective GICNO study. ( Bertorelle, R; Blatt, V; Bonaldi, L; Brandes, AA; Cavallo, G; Ermani, M; Franceschi, E; Gardiman, M; Ghimenton, C; Iuzzolino, P; Pession, A; Reni, M; Tosoni, A, 2006)
"The efficacy and safety of temozolomide were evaluated in 32 patients with anaplastic astrocytoma at first relapse."9.12[Efficacy and safety of monotherapy with temozolomide in patients with anaplastic astrocytoma at first relapse--a phase II clinical study]. ( Aoki, T; Fujimaki, T; Hori, T; Ikeda, J; Kochi, M; Maruno, M; Matsutani, M; Nakamura, H; Nishikawa, R; Sato, S; Sawamura, Y; Shibui, S; Sugiyama, K; Takahashi, H; Takahashi, J; Wakabayashi, T, 2006)
"The combination of TMZ and celecoxib is safe and potentially effective in the treatment of metastatic melanoma."9.12Temozolomide in combination with celecoxib in patients with advanced melanoma. A phase II study of the Hellenic Cooperative Oncology Group. ( Fountzilas, G; Frangia, K; Gogas, H; Mantzourani, M; Markopoulos, C; Middleton, M; Panagiotou, P; Papadopoulos, O; Pectasides, D; Polyzos, A; Stavrinidis, I; Tsoutsos, D; Vaiopoulos, G, 2006)
"To evaluate toxicity and efficacy of the combination of lomustine, temozolomide (TMZ) and involved-field radiotherapy in patients with newly diagnosed glioblastoma (GBM)."9.12Phase II trial of lomustine plus temozolomide chemotherapy in addition to radiotherapy in newly diagnosed glioblastoma: UKT-03. ( Bamberg, M; Blaschke, B; Herrlinger, U; Hundsberger, T; Koch, D; Kortmann, RD; Loeser, S; Meyermann, R; Reifenberger, G; Rieger, J; Sommer, C; Steinbach, JP; Tan, TC; Weller, M; Wick, W, 2006)
"Preliminary studies suggesting that extended-dose temozolomide with thalidomide is safe and active in patients with metastatic melanoma have led to frequent use of this oral regimen."9.12Phase II study of temozolomide and thalidomide in patients with metastatic melanoma in the brain: high rate of thromboembolic events (CALGB 500102). ( Haluska, FG; Hodgson, L; Houghton, AN; Hwu, WJ; Krown, SE; Niedzwiecki, D, 2006)
"Temozolomide has shown some efficacy in metastatic melanoma and recently received extended approval to treat brain tumours."9.12Dose-intensified bi-weekly temozolomide in patients with asymptomatic brain metastases from malignant melanoma: a phase II DeCOG/ADO study. ( Egberts, F; Garbe, C; Hauschild, A; Kreissig, M; Linse, R; Mohr, P; Schadendorf, D; Thoelke, A; Tilgen, W; Trefzer, U; Ugurel, S; Vogt, T, 2006)
" The aim of this pilot study was to evaluate the efficacy and safety of metronomic temozolomide (TMZ) treatment in twelve consecutive patients with recurrent TMZ-refractory glioblastoma."9.12A pilot study of metronomic temozolomide treatment in patients with recurrent temozolomide-refractory glioblastoma. ( Eoh, W; Kim, JH; Kim, ST; Kim, WS; Kong, DS; Lee, JI; Lim, DH; Nam, DH; Park, K; Son, MJ, 2006)
"Laboratory and clinical data suggest that the anti-angiogenic agent, thalidomide, if combined with cytotoxic agents, may be effective against recurrent glioblastoma multiforme (GBM)."9.12A North American brain tumor consortium (NABTC 99-04) phase II trial of temozolomide plus thalidomide for recurrent glioblastoma multiforme. ( Abrey, LE; Chang, SM; Cloughesy, TF; Conrad, CA; DeAngelis, LM; Gilbert, MR; Greenberg, H; Groves, MD; Hess, KR; Lamborn, KR; Liu, TJ; Peterson, P; Prados, MD; Puduvalli, VK; Schiff, D; Tremont-Lukats, IW; Wen, PY; Yung, WK, 2007)
"Temozolomide is an alkylating agent with activity in the treatment of melanoma metastatic to the brain."9.12A phase I/II study of lomustine and temozolomide in patients with cerebral metastases from malignant melanoma. ( Bate, SC; Beirne, DA; Eisen, TG; Gibbens, IM; Gore, ME; Hughes, SA; Larkin, JM; Patel, PM; Thomas, K, 2007)
"Temozolomide (TMZ) has demonstrated activity and acceptable toxicity for the treatment of recurrent malignant gliomas in carious prospective phase II studies."9.12[Temozolomide in the treatment of recurrent malignant glioma]. ( Ishii, N; Iwasaki, Y; Kobayashi, H; Murata, J; Sawamura, Y, 2006)
"The methylation status of the O6-methylguanine-methyltransferase promoter (MGMTP) was evaluated in 68 low-grade gliomas treated by neoadjuvant temozolomide."9.12MGMT methylation: a marker of response to temozolomide in low-grade gliomas. ( Benouaich-Amiel, A; Crinière, E; Delattre, JY; Everhard, S; Hoang-Xuan, K; Kaloshi, G; Kujas, M; Lejeune, J; Marie, Y; Mokhtari, K; Sanson, M; Thillet, J, 2006)
"We conducted a phase II study to assess the efficacy of oral temozolomide (TMZ) in children with progressive low-grade glioma."9.12Temozolomide in children with progressive low-grade glioma. ( Allen, JC; Desjardins, A; Fisher, MJ; Friedman, AH; Friedman, HS; Gururangan, S; Herndon, JE; Krauser, JM; Phillips, PC; Quinn, JA; Reardon, DA; Vredenburgh, JJ; Watral, MA, 2007)
"To evaluate if timing of chemotherapy with Temozolomide (TMZ) was able to modify the outcome of glioblastoma (GBM), we analyzed two comparable series of supratentorial GBM patients, treated with surgery and radiotherapy, in which the administration of TMZ has been performed in the first group at first relapse and in the second group in newly diagnosed cases."9.12Temozolomide in glioblastoma: results of administration at first relapse and in newly diagnosed cases. Is still proposable an alternative schedule to concomitant protocol? ( Borsa, S; Campanella, R; Caroli, M; Gaini, SM; Locatelli, M; Martinelli-Boneschi, F; Mora, A; Motta, F; Prada, F; Saladino, A, 2007)
"This phase II study evaluated the efficacy and safety of a 7-day on/7-day off regimen of temozolomide before radiotherapy (RT) in patients with inoperable newly diagnosed glioblastoma."9.12Correlation between O6-methylguanine-DNA methyltransferase and survival in inoperable newly diagnosed glioblastoma patients treated with neoadjuvant temozolomide. ( Barrié, M; Braguer, D; Chinot, OL; Dufour, H; Eudes, N; Figarella-Branger, D; Fuentes, S; Lancelot, S; Martin, PM; Metellus, P; Muracciole, X; Ouafik, L, 2007)
"Evaluation of toxicity and efficacy of an alternating weekly regimen of temozolomide administered 1 week on and 1 week off in patients with recurrent glioma."9.12Efficacy and tolerability of temozolomide in an alternating weekly regimen in patients with recurrent glioma. ( Blaschke, B; Felsberg, J; Herrlinger, U; Meyermann, R; Platten, M; Reifenberger, G; Steinbach, JP; Weller, M; Wick, A; Wick, W, 2007)
"To determine the maximum tolerated dose of irinotecan when administrated with temozolomide every 28 days, in patients with recurrent malignant glioma who were also receiving CYP450 enzyme-inducing antiepileptic drugs (EIAED), and to characterize the pharmacokinetics of irinotecan and its metabolites."9.12Phase I study of temozolomide and irinotecan for recurrent malignant gliomas in patients receiving enzyme-inducing antiepileptic drugs: a north american brain tumor consortium study. ( Aldape, KD; Chang, SM; Cloughesy, T; DeAngelis, LM; Fine, H; Fink, KL; Junck, L; Kuhn, J; Lamborn, K; Lieberman, F; Loghin, ME; Metha, M; Prados, MD; Robins, IH; Wen, P; Yung, WK, 2007)
"Patients with recurrent malignant glioma at any time during recurrence were treated with oral temozolomide at a dose of 150 mg/m2 per day on a 5-day schedule every 28 days."9.11Temozolomide in the treatment of recurrent malignant glioma. ( Chang, SM; Lamborn, K; Malec, M; Page, M; Prados, MD; Rabbitt, J; Theodosopoulos, P, 2004)
"The purpose of this study was to evaluate the activity, measured in terms of progression-free survival (PFS) and response rates, of 1,3-bis(chloro-ethyl)-1-nitrosourea (BCNU) plus temozolomide in adult patients with recurrent glioblastoma multiforme."9.11Phase 2 study of BCNU and temozolomide for recurrent glioblastoma multiforme: North American Brain Tumor Consortium study. ( Chang, SM; Fine, HA; Fink, KL; Greenberg, HS; Hess, KR; Jaeckle, KA; Junck, L; Kuhn, J; Mehta, MP; Nicholas, MK; Prados, MD; Robins, HI; Schold, SC; Yung, WK, 2004)
"Temozolomide has established activity in the treatment of recurrent glioblastoma multiforme (GBM)."9.11Phase 2 study of temozolomide and Caelyx in patients with recurrent glioblastoma multiforme. ( Ashley, DM; Cher, LM; Chua, SL; Dowling, A; Rosenthal, MA; Wong, SS; Woods, AM, 2004)
"We report a phase II trial of cisplatinum and temozolomide (TMZ) combination in recurrent malignant glioma patients."9.11Phase II trial of cisplatin plus temozolomide, in recurrent and progressive malignant glioma patients. ( Boiardi, A; Broggi, G; Eoli, M; Lamperti, E; Maccagnano, E; Salmaggi, A; Silvani, A, 2004)
"The primary objective of the current prospective Phase II study of cyclophosphamide (CYC) in adult patients with recurrent, temozolomide-refractory glioblastoma multiforme was to evaluate 6-month progression-free survival (PFS)."9.11Salvage chemotherapy with cyclophosphamide for recurrent, temozolomide-refractory glioblastoma multiforme. ( Chamberlain, MC; Tsao-Wei, DD, 2004)
"In the setting of a prospective clinical trial, we determined the predictive value of the methylation status of the O-6-methylguanine-DNA methyltransferase (MGMT) promoter for outcome in glioblastoma patients treated with the alkylating agent temozolomide."9.11Clinical trial substantiates the predictive value of O-6-methylguanine-DNA methyltransferase promoter methylation in glioblastoma patients treated with temozolomide. ( de Tribolet, N; Dietrich, PY; Diserens, AC; Godard, S; Hegi, ME; Ostermann, S; Otten, P; Regli, L; Stupp, R; Van Melle, G, 2004)
"Temozolomide (TMZ) and 1, 3-bis (2-chloroethyl)-1-nitrosourea (BCNU) are reported to be active agents in anaplastic glioma (AG)."9.11Phase II study of neoadjuvant 1, 3-bis (2-chloroethyl)-1-nitrosourea and temozolomide for newly diagnosed anaplastic glioma: a North American Brain Tumor Consortium Trial. ( Chang, SM; Fine, H; Fink, KL; Greenberg, H; Hess, K; Jaeckle, KA; Junck, L; Kuhn, J; Mehta, M; Prados, MD; Robins, HI; Schold, C; Yung, WK, 2004)
"Cisplatin and temozolomide (TMZ) are active in glioblastoma multiforme (GBM), with different profiles of toxicity."9.11First-line chemotherapy with cisplatin plus fractionated temozolomide in recurrent glioblastoma multiforme: a phase II study of the Gruppo Italiano Cooperativo di Neuro-Oncologia. ( Basso, U; Brandes, AA; Cavallo, G; Ermani, M; Ferreri, AJ; Monfardini, S; Panucci, MG; Reni, M; Scopece, L; Tosoni, A; Vastola, F, 2004)
"To determine the safety and toxicity of carmustine (BCNU) and temozolomide (TMZ) with radiotherapy (RT) in newly diagnosed anaplastic astrocytoma."9.11Phase I study pilot arms of radiotherapy and carmustine with temozolomide for anaplastic astrocytoma (Radiation Therapy Oncology Group 9813): implications for studies testing initial treatment of brain tumors. ( Atkins, J; Bahary, JP; Barger, G; Buckner, J; Bushunow, P; Cairncross, G; Chang, SM; Choucair, A; Curran, W; Dolinskas, C; Gilbert, M; Kresl, J; Louis, DN; Mehta, M; Seiferheld, W; Share, R; Thoron, L, 2004)
"This report describes a single-centre study with temozolomide (TMZ) (200 mg m(-2) day(-1) x 5 per cycle of 28 days) in children with (recurrent) high-grade glioma."9.11Temozolomide in paediatric high-grade glioma: a key for combination therapy? ( Couanet, D; Grill, J; Kalifa, C; Lelouch-Tubiana, A; Vassal, G; Verschuur, AC, 2004)
"The authors investigated the results of PCV chemotherapy within a cohort of 24 patients treated within the EORTC study 26971 on temozolomide chemotherapy in recurrent oligodendroglioma."9.11Salvage PCV chemotherapy for temozolomide-resistant oligodendrogliomas. ( Allgeier, A; Brandes, AA; Enting, RH; Frenay, M; Kros, JM; Menten, J; Stege, EB; Taphoorn, MJ; Tosoni, A; Triebels, VH; van den Bent, MJ; van Heuvel, I, 2004)
"Thirty-two patients with relapsing glioma were treated with temozolomide in two university hospitals in Finland."9.11Temozolomide treatment in glioma--experiences in two university hospitals in Finland. ( Aaltonen, K; Mäenpää, HO; Mäntylä, R; Minn, H, 2004)
"An analysis of 73 patients with hystologically confirmed glioblastoma multiforme (GBM), treated with the ''3 step'' (90)Y-biotin based LR-RIT, is herein reported."9.11Combined treatment of glioblastoma patients with locoregional pre-targeted 90Y-biotin radioimmunotherapy and temozolomide. ( Bartolomei, M; Bodei, L; Grana, C; Handkiewicz-Junak, D; Maira, G; Mazzetta, C; Paganelli, G; Rocca, P; Sturiale, C; Villa, G, 2004)
"Seventy-five consecutive patients with recurrent malignant astrocytomas and glioblastomas had been treated at our institute with per os temozolomide for five days every month."9.11Temozolomide chemotherapy of patients with recurrent anaplastic astrocytomas and glioblastomas. ( Afra, D; Sipos, L; Vitanovics, D, 2004)
"This phase II study evaluates the activity of temozolomide and cisplatin administered before radiation therapy in newly diagnosed glioblastoma multiforme patients, in terms of response, time to progression and survival."9.11Phase II study of temozolomide and cisplatin as primary treatment prior to radiotherapy in newly diagnosed glioblastoma multiforme patients with measurable disease. A study of the Spanish Medical Neuro-Oncology Group (GENOM). ( Balaña, C; Balart, J; Ballester, R; Benavides, M; Berrocal, A; Capellades, J; Cerdá-Nicolás, M; García, JL; Herrero, A; López-Pousa, A; Martín-Broto, J; Yaya-Tur, R, 2004)
"Patients with newly diagnosed, histologically confirmed glioblastoma were randomly assigned to receive radiotherapy alone (fractionated focal irradiation in daily fractions of 2 Gy given 5 days per week for 6 weeks, for a total of 60 Gy) or radiotherapy plus continuous daily temozolomide (75 mg per square meter of body-surface area per day, 7 days per week from the first to the last day of radiotherapy), followed by six cycles of adjuvant temozolomide (150 to 200 mg per square meter for 5 days during each 28-day cycle)."9.11Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma. ( Allgeier, A; Belanger, K; Bogdahn, U; Brandes, AA; Cairncross, JG; Curschmann, J; Eisenhauer, E; Fisher, B; Gorlia, T; Janzer, RC; Lacombe, D; Ludwin, SK; Marosi, C; Mason, WP; Mirimanoff, RO; Stupp, R; Taphoorn, MJ; van den Bent, MJ; Weller, M, 2005)
"Temozolomide plus thalidomide was an active oral regimen for patients with brain metastases from malignant melanoma."9.11Temozolomide plus thalidomide in patients with brain metastases from melanoma: a phase II study. ( Chapman, PB; Houghton, AN; Hwu, WJ; Krown, SE; Lamb, LA; Lis, E; Livingston, PO; Menell, JH; Merrell, J; Panageas, KS; Williams, LJ; Wolchok, JD, 2005)
"The authors determined the maximum tolerated dose (MTD) and dose-limiting toxicity (DLT) of irinotecan (CPT-11), a topoisomerase I inhibitor, when administered with temozolomide among patients with recurrent malignant glioma (MG)."9.11Phase I trial of irinotecan plus temozolomide in adults with recurrent malignant glioma. ( Badruddoja, M; Burkart, JL; Desjardins, A; Dowell, JM; Friedman, AH; Friedman, HS; Gururangan, S; Herndon, JE; McLendon, R; Newton, HB; Provenzale, J; Quinn, JA; Reardon, DA; Rich, JN; Sathornsumetee, S; Vredenburgh, J, 2005)
" Food and Drug Administration approved temozolomide (Temodar capsules, Schering-Plough Research Institute) for the treatment of adult patients with newly diagnosed glioblastoma multiforme concomitantly with radiotherapy and then as maintenance treatment."9.11Food and Drug Administration Drug approval summary: temozolomide plus radiation therapy for the treatment of newly diagnosed glioblastoma multiforme. ( Cohen, MH; Johnson, JR; Pazdur, R, 2005)
"To determine the anti-tumour efficacy and safety profile of temozolomide in local Chinese patients with recurrent malignant glioma."9.11Temozolomide in the treatment of recurrent malignant glioma in Chinese patients. ( Chan, DT; Chan, YL; Ng, HK; Poon, WS, 2005)
"In an effort to reduce the frequency of central nervous system (CNS) progression in patients with metastatic melanoma with ongoing systemic response to biochemotherapy, we modified our standard concurrent biochemotherapy regimen by replacing dacarbazine (DTIC) with oral temozolomide."9.10A phase II pilot trial of concurrent biochemotherapy with cisplatin, vinblastine, temozolomide, interleukin 2, and IFN-alpha 2B in patients with metastatic melanoma. ( Atkins, MB; Gollob, JA; McDermott, DF; Mier, JW; Parker, RA; Sorokin, P; Sosman, JA; Tutin, L, 2002)
"To determine the response rate of the malignant gliomas of childhood to an oral, daily schedule of temozolomide."9.10Temozolomide in malignant gliomas of childhood: a United Kingdom Children's Cancer Study Group and French Society for Pediatric Oncology Intergroup Study. ( Couanet, D; Doz, F; Dugan, M; Frappaz, D; Griffiths, PD; Hobson, R; Ironside, J; Jaspan, T; Jouvet, A; Lashford, LS; Pearson, AD; Robson, K; Thiesse, P; Vassal, G, 2002)
"Although temozolomide is active against recurrent malignant glioma, responses in many patients are modest and short-lived."9.10Phase I study of temozolomide and escalating doses of oral etoposide for adults with recurrent malignant glioma. ( Benita-Weiss, M; Bushunow, P; Coyle, TE; Evans, B; Friedman, H; Korones, DN; Mechtler, L; Quinn, JA; Reardon, DA, 2003)
"Temozolomide (TMZ) is an oral alkylating agent with a good safety profile and proven efficacy in the treatment of malignant glioma."9.10Phase I study of temozolamide (TMZ) combined with procarbazine (PCB) in patients with gliomas. ( Foster, T; Newlands, ES; Zaknoen, S, 2003)
"To further investigate the efficacy and safety of temozolomide plus thalidomide in patients with metastatic melanoma without brain metastases."9.10Phase II study of temozolomide plus thalidomide for the treatment of metastatic melanoma. ( Chapman, PB; Foster, T; Houghton, AN; Hwu, WJ; Krown, SE; Lamb, LA; Livingston, PO; Menell, JH; Merrell, J; Panageas, KS; Quinn, CJ; Williams, LJ; Wolchok, JD, 2003)
"The aim of this study was to assess the efficacy of temozolomide in patients with World Health Organisation (WHO) grade II gliomas treated with surgery alone using imaging and clinical criteria."9.10Phase II study of primary temozolomide chemotherapy in patients with WHO grade II gliomas. ( Abson, C; Ashley, S; Brada, M; Britton, J; Gonsalves, A; Hines, F; Sardell, S; Traish, D; Viviers, L; Westbury, C; Wilkins, P, 2003)
"Forty-three patients affected with LGG (29 astrocytoma, four oligodendroglioma and 10 mixed oligo-astrocytoma) were treated with temozolomide (TMZ) at the time of documented clinical and radiological progression."9.10Temozolomide chemotherapy for progressive low-grade glioma: clinical benefits and radiological response. ( Canalini, P; Carapella, CM; Carosi, M; Cianciulli, AM; Galiè, E; Giannarelli, D; Jandolo, B; Pace, A; Telera, S; Vidiri, A, 2003)
"Temozolomide is an effective agent in the treatment of recurrent malignant gliomas."9.10A phase II study of extended low-dose temozolomide in recurrent malignant gliomas. ( Abrey, LE; Bazylewicz, KA; Khan, RB; Malkin, MG; Raizer, JJ, 2002)
"Temozolomide is a novel oral alkylating agent that is effective against melanoma."9.10Temozolomide in combination with docetaxel in patients with advanced melanoma: a phase II study of the Hellenic Cooperative Oncology Group. ( Bafaloukos, D; Briassoulis, E; Fountzilas, G; Georgoulias, V; Gogas, H; Kalofonos, Ch; Karabelis, A; Kosmidis, P; Samantas, E; Skarlos, D, 2002)
"Temozolomide is a novel oral alkylating agent with demonstrated efficacy as second-line therapy for patients with recurrent anaplastic astrocytoma and glioblastoma multiforme (GBM)."9.10Promising survival for patients with newly diagnosed glioblastoma multiforme treated with concomitant radiation plus temozolomide followed by adjuvant temozolomide. ( de Tribolet, N; Dietrich, PY; Janzer, R; Leyvraz, S; Maeder, P; Maillard, I; Meuli, R; Miralbell, R; Mirimanoff, RO; Ostermann Kraljevic, S; Pica, A; Pizzolato, G; Porchet, F; Regli, L; Stupp, R, 2002)
"Temozolomide has shown efficacy in the treatment of metastatic melanoma similar to that of dacarbazine (DTIC), the standard chemotherapy, but with the added benefit of penetration into the central nervous system (CNS)."9.10Effect of temozolomide on central nervous system relapse in patients with advanced melanoma. ( Brampton, MH; Calvert, AH; Middleton, MR; Paul, MJ; Rustin, G; Summers, Y; Thatcher, N, 2002)
"To evaluate the antitumor effects and toxicities of whole brain irradiation (WBI) with temozolomide (TMZ) administered by prolonged oral dosing in patients with melanoma metastatic to the brain."9.10Temozolomide and whole brain irradiation in melanoma metastatic to the brain: a phase II trial of the Cytokine Working Group. ( Atkins, B; Clark, I; Dutcher, P; Ernstoff, S; Flaherty, L; Gollob, J; II Smith, W; Johnson, D; Longmate, J; Margolin, K; Sosman, J; Thompson, A; Weber, J; Weiss, G, 2002)
"To determine the antitumor efficacy and safety profile of temozolomide in patients with malignant astrocytoma at first relapse."9.09Multicenter phase II trial of temozolomide in patients with anaplastic astrocytoma or anaplastic oligoastrocytoma at first relapse. Temodal Brain Tumor Group. ( Albright, R; Brada, M; Bruner, J; Chang, SM; Dugan, M; Friedman, AH; Friedman, HS; Levin, VA; O'Neill, AM; Olson, J; Prados, MD; Rosenfeld, SS; Yaya-Tur, R; Yue, N; Yung, WK; Zaknoen, S, 1999)
"To determine whether chemotherapy with temozolomide (TMZ) versus procarbazine (PCB) for recurrent glioblastoma multiforme (GBM) was associated with improvement in health-related quality of life (HRQOL)."9.09Health-related quality of life in patients treated with temozolomide versus procarbazine for recurrent glioblastoma multiforme. ( Brada, M; Osoba, D; Prados, M; Yung, WK, 2000)
"A randomized, multicentre, open-label, phase II study compared temozolomide (TMZ), an oral second-generation alkylating agent, and procarbazine (PCB) in 225 patients with glioblastoma multiforme at first relapse."9.09A phase II study of temozolomide vs. procarbazine in patients with glioblastoma multiforme at first relapse. ( Albright, RE; Brada, M; Bruner, J; Fink, K; Fredericks, R; Friedman, H; Glantz, M; Greenberg, H; Hohl, RJ; Levin, VA; Olson, J; Osoba, D; Phillips, P; Prados, MD; Rampling, R; Selker, RG; Shapiro, W; Spence, A; Vick, NA; Yue, N; Yung, WK; Zaknoen, S, 2000)
"One of the objectives of this phase II study was to determine whether temozolomide (TMZ) improved the health-related quality of life (HRQL) of patients with recurrent anaplastic astrocytoma (AA)."9.09Health-related quality of life in patients with anaplastic astrocytoma during treatment with temozolomide. ( Brada, M; Osoba, D; Prados, MD; Yung, WK, 2000)
"Forty-one patients with high-grade glioma, at second recurrence or progression, of which twenty-two (54%) had glioblastoma multiforme, ten (24%) anaplastic astrocytoma, and nine (22%) anaplastic oligodendroglioma were administered temozolomide, 150 mg/m2/daily for five days every four weeks."9.09Temozolomide as a second-line systemic regimen in recurrent high-grade glioma: a phase II study. ( Amistà, P; Basso, U; Berti, F; Brandes, AA; Ermani, M; Gardiman, M; Monfardini, S; Pinna, G; Rotilio, A; Scienza, R, 2001)
"We report an open-label, uncontrolled, multicenter phase II trial of temozolomide in 138 patients (intent-to-treat [ITT] population) with glioblastoma multiforme at first relapse and a Karnofsky performance status (KPS) > or = 70."9.09Multicenter phase II trial of temozolomide in patients with glioblastoma multiforme at first relapse. ( Brada, M; Bravo-Marques, JM; Bruner, J; Dietrich, PY; Dirix, LY; Dugan, M; Heimans, JJ; Henriksson, R; Hoang-Xuan, K; Macdonald, D; Rampling, R; Rao, S; Stupp, R; Yue, N; Zaknoen, S; Zonnenberg, BA, 2001)
" A novel second-generation alkylating agent, temozolomide, has recently demonstrated efficacy and safety in patients with recurrent glioblastoma multiforme and anaplastic astrocytoma."9.09Safety and efficacy of temozolomide in patients with recurrent anaplastic oligodendrogliomas after standard radiotherapy and chemotherapy. ( Barrie, M; Braguer, D; Chinot, OL; Dufour, H; Figarella-Branger, D; Grisoli, F; Honore, S; Martin, PM; Muracciole, X, 2001)
"Temozolomide, a new oral cytotoxic agent, was given to 75 patients with malignant gliomas."9.08The Charing Cross Hospital experience with temozolomide in patients with gliomas. ( Bower, M; Brampton, MH; Brock, C; Colquhoun, I; Evans, H; Glaser, MG; Illingworth, RD; Lewis, P; Newlands, ES; O'Reilly, SM; Rice-Edwards, JM; Richards, PG, 1996)
"Patients with progressive or recurrent supratentorial high-grade gliomas were entered into a multicentre phase II trial to evaluate the efficacy and toxicity of temozolomide."9.08Multicentre CRC phase II trial of temozolomide in recurrent or progressive high-grade glioma. ( Begent, RJ; Bleehen, NM; Bower, M; Brada, M; Brampton, MH; Calvert, H; Colquhoun, I; Lewis, P; Newlands, ES, 1997)
"The majority of patients with high-risk lower grade gliomas (LGG) are treated with single-agent temozolomide (TMZ) and radiotherapy despite three randomized trials showing a striking overall survival benefit with adjuvant procarbazine, lomustine, and vincristine (PCV) chemotherapy and radiotherapy."9.05Radiation and chemotherapy for high-risk lower grade gliomas: Choosing between temozolomide and PCV. ( Atkins, KM; Dietrich, J; Loeffler, JS; McDuff, SGR; Oh, KS; Shih, HA, 2020)
"The efficacy of radiotherapy with adjuvant temozolomide for glioblastoma remains controversial."9.05The efficacy and safety of radiotherapy with adjuvant temozolomide for glioblastoma: A meta-analysis of randomized controlled studies. ( Feng, Y; Wang, Y, 2020)
"Glioblastoma (GB) is one of the most common malignancies with limited standard therapies such as surgery, radiotherapy (RT) plus temozolomide (TMZ)."9.01Prognosis of patients with newly diagnosed glioblastoma treated with molecularly targeted drugs combined with radiotherapy vs temozolomide monotherapy: A meta-analysis. ( Aru, N; Ding, YM; Jin, WY; Liu, Z; Qin, HH; Shen, X; Wang, WL; Wu, SJ, 2019)
"Temozolomide is a first-line treatment for newly diagnosed glioblastoma."9.01Evidence-Based Practice: Temozolomide Beyond Glioblastoma. ( Chua, J; Leung, D; Nafziger, E, 2019)
"Here we review tumoricidal efficacy of Vitamin D analogues in glioblastoma multiforme (GBM) and potential synergisms with retinoic acid and temozolomide based on epidemiological and cellular studies."9.01From epidemiology and neurometabolism to treatment: Vitamin D in pathogenesis of glioblastoma Multiforme (GBM) and a proposal for Vitamin D + all-trans retinoic acid + Temozolomide combination in treatment of GBM. ( Altinoz, MA; Elmaci, I; Ozpinar, A; Perez, JL, 2019)
"Although reoperation likely confers survival benefit for glioblastoma, whether the extent of resection (EOR) of the reoperation affects survival outcome has yet to be thoroughly evaluated in the current temozolomide (TMZ) era."9.01Survival Benefit of Maximal Resection for Glioblastoma Reoperation in the Temozolomide Era: A Meta-Analysis. ( Burns, TC; Chaichana, KL; Goyal, A; Graffeo, CS; Lu, VM; Parney, IF; Perry, A; Quinones-Hinojosa, A, 2019)
"Temozolomide is the most widely used chemotherapy for patients with glioblastoma (GBM) despite the fact that approximately half of treated patients have temozolomide resistance and all patients eventually fail therapy."8.98Temozolomide for immunomodulation in the treatment of glioblastoma. ( Dastmalchi, F; Karachi, A; Mitchell, DA; Rahman, M, 2018)
"To assess the effectiveness and safety of procarbazine, lomustine, and vincristine (PCV) chemotherapy with other interventions in adults with recurrent high-grade glioma."8.95Procarbazine, lomustine and vincristine for recurrent high-grade glioma. ( Guo, J; Parasramka, S; Rosenfeld, M; Talari, G; Villano, JL, 2017)
"There is a growing body of evidence that carmustine wafer implantation during surgery is an effective therapeutic adjunct to the standard combined radio-chemotherapy regimen using temozolomide in newly diagnosed and recurrent high-grade glioma patient management with a statistically significant survival benefit demonstrated across several randomized clinical trials, as well as prospective and retrospective studies (grade A recommendation)."8.95Carmustine wafer implantation for high-grade gliomas: Evidence-based safety efficacy and practical recommendations from the Neuro-oncology Club of the French Society of Neurosurgery. ( Caire, F; Guyotat, J; Menei, P; Metellus, P; Pallud, J; Roux, A, 2017)
"The current meta-analysis evaluated the survival outcomes of newly diagnosed glioblastoma patients treated with radiotherapy (RT) alone and with RT + temozolomide (TMZ)."8.95Temozolomide with or without Radiotherapy in Patients with Newly Diagnosed Glioblastoma Multiforme: A Meta-Analysis. ( Feng, E; Sui, C; Sun, G; Wang, T, 2017)
"This review article summarizes in vitro, in vivo, and clinical evidence pertaining to temozolomide (TMZ) and bevacizumab (BEV) efficacy and mechanism of action in gliomas."8.91Current evidence of temozolomide and bevacizumab in treatment of gliomas. ( Chattipakorn, N; Chattipakorn, SC; Nanegrungsunk, D; Onchan, W, 2015)
"Long-term temozolomide might be an optimal choice for patients with multifocal glioblastoma, especially with deep-seated structure involvement."8.91Long-term temozolomide might be an optimal choice for patient with multifocal glioblastoma, especially with deep-seated structure involvement: a case report and literature review. ( Gao, Z; Hao, S; Liu, Y; Yu, L, 2015)
"The goal of this meta-analysis was to identify the temozolomide (TMZ) regimen with optimal efficacy and tolerance for treatment of recurrent high-grade glioma (HGG)."8.91The efficacy and safety of various dose-dense regimens of temozolomide for recurrent high-grade glioma: a systematic review with meta-analysis. ( Chen, X; Guo, Z; Ma, X; Wang, D; Wei, W, 2015)
" The authors hereby, evaluated the use of temozolomide (TMZ) for treating metastatic melanoma compared to dacarbazine (DTIC), the effectiveness of TMZ for treating brain metastases, as well as TMZ resistance and how the efficacy of TMZ in malignant melanoma can be increased."8.91Temozolomide for Treating Malignant Melanoma. ( Hou, XY; Jiang, G; Li, RH; Liu, WL; Liu, YQ; Tang, JQ; Yang, CS, 2015)
"Temozolomide (TMZ) alone has been proposed as a promising alternative to radiotherapy (RT) in elderly glioblastoma (GBM) patients."8.90A meta-analysis of temozolomide versus radiotherapy in elderly glioblastoma patients. ( Cai, S; Cheng, JX; Dong, Y; Liu, BL; Yin, AA; Zhang, LH; Zhang, X, 2014)
"This analysis was conducted to evaluate the efficacy and safety of temozolomide based chemotherapy in treating patients with glioma."8.90Comprehensive analysis of temozolomide treatment for patients with glioma. ( Liang, H; Xing, BZ; Yang, WB, 2014)
"Temozolomide (TMZ) is an alkylating agent currently used as first-line therapy for gliomas treatment due to its DNA-damaging effect."8.89O6-methylguanine DNA methyltransferase as a promising target for the treatment of temozolomide-resistant gliomas. ( Cao, H; Chen, L; Fan, CH; Jiang, G; Liu, WL; Wen, C, 2013)
"The efficacy of temozolomide (TMZ) in recurrent glioblastoma multiforme (GBM) has been evaluated by several clinical trials."8.89The efficacy of temozolomide for recurrent glioblastoma multiforme. ( Chen, C; Chen, J; Lu, Y; Wu, S; Xu, T, 2013)
"We searched three online databases to systematically identify publications testing temozolomide in animal models of glioma."8.89Systematic review and meta-analysis of temozolomide in animal models of glioma: was clinical efficacy predicted? ( Egan, KJ; Hirst, TC; Macleod, MR; Sena, ES; Vesterinen, HM; Whittle, IR, 2013)
"The landmark Stupp study demonstrated a survival advantage with concomitant and adjuvant temozolomide (TMZ) with standard radiotherapy (RT) in glioblastoma multiforme (GBM) patients but excluded those older than 70 years."8.88Hypofractionated radiotherapy with or without concurrent temozolomide in elderly patients with glioblastoma multiforme: a review of ten-year single institutional experience. ( Bauman, GS; Cao, JQ; Fisher, BJ; Macdonald, DR; Megyesi, JF; Watling, CJ, 2012)
"This article provides historical and recent perspectives related to the use of temozolomide for the treatment of glioblastoma multiforme."8.88Temozolomide and other potential agents for the treatment of glioblastoma multiforme. ( Chow, F; Cremer, N; Kim, W; Nagasawa, DT; Yang, I; Yew, A, 2012)
"The standard therapy for newly diagnosed malignant gliomas comprises surgery, radiotherapy, and commonly temozolomide chemotherapy."8.87An algorithm for chemotherapy treatment of recurrent glioma patients after temozolomide failure in the general oncology setting. ( Kyritsis, AP; Levin, VA, 2011)
"Temozolomide-based chemotherapy represents an incremental improvement in the treatment of patients with high-grade gliomas."8.86Temozolomide: therapeutic limitations in the treatment of adult high-grade gliomas. ( Chamberlain, MC, 2010)
"One barrier to successful treatment of malignant glioma is resistance to alkylating agents such as temozolomide."8.85New (alternative) temozolomide regimens for the treatment of glioma. ( Platten, M; Weller, M; Wick, W, 2009)
"Patients with brain metastasis were identified from 3 prospective studies of temozolomide (with or without immunotherapy) for metastatic melanoma."8.84Temozolomide in advanced malignant melanoma with small brain metastases: can we withhold cranial irradiation? ( Boogerd, W; Dalesio, O; de Gast, GC, 2007)
" In this paper we address different clinical outcomes measures separately and we illustrate the value of multiple outcome measures using the results of a recent clinical trial comparing temozolomide with procarbazine in the treatment of Glioblastoma Multiforme."8.82Benefit of temozolomide compared to procarbazine in treatment of glioblastoma multiforme at first relapse: effect on neurological functioning, performance status, and health related quality of life. ( Kiebert, G; Macdonald, DR; Olson, J; Prados, M; Yung, A, 2005)
"Temozolomide (TMZ) has been used as standard-of-care for glioblastoma multiforme (GBM), but the resistance to TMZ develops quickly and frequently."8.31Involvement of cell shape and lipid metabolism in glioblastoma resistance to temozolomide. ( An, YJ; Choo, M; Kim, DH; Kim, HS; Ku, JL; Lee, SK; Mai, VH; Park, CK; Park, S, 2023)
"Temozolomide (TMZ) is the recommended drug for glioblastoma (GBM) treatment, but its clinical effect is restricted due to drug resistance."8.31Implication of lncRNA ZBED3-AS1 downregulation in acquired resistance to Temozolomide and glycolysis in glioblastoma. ( Dong, J; Jiang, Z; Peng, Y; Wang, K; Wu, Y; Xie, Z; Zhong, M, 2023)
"Temozolomide (TMZ) has been determined to be the chemotherapeutic drug with efficacy for glioblastoma (GBM)."8.31Ultrasound-excited temozolomide sonosensitization induces necroptosis in glioblastoma. ( Song, S; Tong, X; Wang, F; Wang, Y; Wen, B; Wu, H; Wu, Q; Xu, L; Yan, H; Zhou, Y, 2023)
"Complete resection of glioblastoma via a supraorbital transciliary approach with 5-Aminolevulinic Acid use was performed without any complications, as demonstrated on postoperative MRI."8.31Supraorbital transciliary approach as primary route to fronto-basal high grade glioma resection with 5-Aminolevulinic Acid use: Technical note. ( Aboukaïs, R; Bourgeois, P; Devalckeneer, A; Lejeune, JP; Reyns, N, 2023)
"Temozolomide (TMZ) is a conventional chemotherapeutic drug for glioma, however, its clinical application and efficacy is severely restricted by its drug resistance properties."8.31The nanoprodrug of polytemozolomide combines with MGMT siRNA to enhance the effect of temozolomide in glioma. ( Li, L; Liu, H; Ma, H; Qian, F; Quan, A; Ren, Y; Wang, L; Xu, H; Yu, R; Zhang, Y, 2023)
" In this study, we investigated the role of KDM1A/LSD1 in DNA double-strand break (DSB) repair and a combination of KDM1A inhibitor and temozolomide (TMZ) in vitro and in vivo using patient-derived glioma stem cells (GSCs)."8.31Lysine-specific histone demethylase 1A (KDM1A/LSD1) inhibition attenuates DNA double-strand break repair and augments the efficacy of temozolomide in glioblastoma. ( Alejo, S; Brenner, AJ; Chen, Y; Clarke, K; Gilbert, AR; He, Y; Jayamohan, S; Johnson, JD; Lai, Z; Li, W; Lv, Y; Palacios, BE; Pratap, UP; Sareddy, GR; Suzuki, T; Tekmal, RR; Vadlamudi, RK; Venkata, PP; Viswanadhapalli, S; Weldon, K; Ye, Z; Zhao, W; Zheng, S; Zou, Y, 2023)
"Although temozolomide (TMZ) provides significant clinical benefit for glioblastoma (GBM), responses are limited by the emergence of acquired resistance."8.31Exosome-transmitted circCABIN1 promotes temozolomide resistance in glioblastoma via sustaining ErbB downstream signaling. ( Cao, Z; Gao, G; Gu, J; Guan, Z; Guo, Q; Hao, Q; Jia, B; Li, M; Li, W; Liu, X; Wang, S; Wang, W; Zhang, K; Zhang, W; Zhang, Y, 2023)
"The development of resistance to temozolomide (TMZ), a standard chemotherapeutic, limits the effective treatment of glioblastoma (GBM)."8.31The PYK2 inhibitor PF-562271 enhances the effect of temozolomide on tumor growth in a C57Bl/6-Gl261 mouse glioma model. ( Kucheryavykh, L; Kucheryavykh, Y; Nuñez, R; Ortiz-Rivera, J, 2023)
" We aimed to clarify the interplay between purinergic signaling and chemotherapeutic drug temozolomide (TMZ) in human glioma cell line."8.31Purinergic approach to effective glioma treatment with temozolomide reveals enhanced anti-cancer effects mediated by P2X7 receptor. ( Czach, S; Czarnecka, J; Nowak, W; Roszek, K; Szymczak, B, 2023)
"Temozolomide (TMZ) is one of the best choices for treating glioblastoma."8.31Exploring temozolomide encapsulated PEGylated liposomes and lyotropic liquid crystals for effective treatment of glioblastoma: in-vitro, cell line, and pharmacokinetic studies. ( Laxmi Swetha, K; Narayan Saha, R; Roy, A; Singhvi, G; Waghule, T, 2023)
"Temozolomide (TMZ) is the preferred chemotherapy strategy for glioma therapy."8.31Gut microbiota mediated the individualized efficacy of Temozolomide via immunomodulation in glioma. ( Deng, Y; Du, H; Hou, X; Liu, J; Liu, W; Liu, Y; Qiao, J; Shu, X; Sun, B; Wang, H, 2023)
" Protein disulfide isomerase (PDI) is a molecular chaperone known to be highly expressed in glioblastomas with acquired resistance to temozolomide (TMZ)."8.31Targeting unfolded protein response using albumin-encapsulated nanoparticles attenuates temozolomide resistance in glioblastoma. ( Kiang, KM; Lam, TL; Leung, GK; Li, N; Liu, J; Shum, HC; Song, Q; Tang, W; Zhu, Z, 2023)
"The chemoresistance of temozolomide-based therapy is a serious limitation for lasting effective treatment of gliomas, while the underlying mechanisms remain unclear."8.31Downregulation of BASP1 Promotes Temozolomide Resistance in Gliomas via Epigenetic Activation of the FBXO32/NF-κB/MGMT Axis. ( Chen, S; Li, J; Li, M; Li, X; Li, Z; Liao, X; Qian, W; Song, L; Tang, M; Xu, Y; Yu, R; Zhang, S; Zheng, H, 2023)
"Temozolomide (TMZ)-based chemotherapy plays a central part in glioma treatment."8.31SRSF4 Confers Temozolomide Resistance of Glioma via Accelerating Double Strand Break Repair. ( Liu, X; Sun, Y; Wang, X; Wu, Z; Yan, W; You, Y; Zhang, Y, 2023)
" TTFields therapy is approved for treatment of newly-diagnosed glioblastoma (GBM) concurrent with maintenance temozolomide (TMZ)."8.31Tumor Treating Fields (TTFields) increase the effectiveness of temozolomide and lomustine in glioblastoma cell lines. ( Dor-On, E; Fishman, H; Giladi, M; Haber, A; Kinzel, A; Monin, R; Palti, Y; Weinberg, U, 2023)
"Glioblastoma (GBM) is a malignant brain tumor, commonly treated with temozolomide (TMZ)."8.31ADAM17 Confers Temozolomide Resistance in Human Glioblastoma Cells and miR-145 Regulates Its Expression. ( Chen, JC; Chong, ZY; Huang, C; Huang, HC; Lee, IN; Wu, YP; Yang, JT, 2023)
"Patients with glioblastoma (GBM) have poor prognosis and limited therapeutic options, largely because of chemoresistance to temozolomide (TMZ) treatment."8.31UBE2T Promotes Temozolomide Resistance of Glioblastoma Through Regulating the Wnt/β-Catenin Signaling Pathway. ( Gao, G; Wang, Y; Wei, X; Yu, J; Zhang, Y, 2023)
"Temozolomide resistance remains a major obstacle in the treatment of glioblastoma (GBM)."8.31The DRD2 Antagonist Haloperidol Mediates Autophagy-Induced Ferroptosis to Increase Temozolomide Sensitivity by Promoting Endoplasmic Reticulum Stress in Glioblastoma. ( Chen, H; Chen, K; Chen, L; Huang, A; Huang, Y; Li, C; Li, H; Lu, Y; Qi, S; Shi, L; Song, C; Wang, T; Zhong, C, 2023)
"Chemoresistance blunts the efficacy of temozolomide (TMZ) in the treatment of glioblastoma (GBM)."8.31Resveratrol Enhances Temozolomide Efficacy in Glioblastoma Cells through Downregulated MGMT and Negative Regulators-Related STAT3 Inactivation. ( Ahmad, N; Cheng, X; Deng, S; Li, H; Shu, X; Song, D; Wang, Q; Wu, M; Xu, H; Yang, X, 2023)
"Glioblastoma multiforme (GBM) is the deadliest glioma and its resistance to temozolomide (TMZ) remains intractable."8.31HOXD-AS2-STAT3 feedback loop attenuates sensitivity to temozolomide in glioblastoma. ( Cao, YY; Chen, JX; Chen, QZ; Huang, GH; Li, Y; Liu, GL; Lv, SQ; Pei, YC; Ren, P; Wang, TT; Xiang, Y; Yang, L; Yang, W; Zhang, ZX; Zhou, S, 2023)
"To explore the role of forkhead box protein O1 (FOXO1) in the progression of glioblastoma multiforme (GBM) and related drug resistance, we deciphered the roles of FOXO1 and miR-506 in proliferation, apoptosis, migration, invasion, autophagy, and temozolomide (TMZ) sensitivity in the U251 cell line using in vitro and in vivo experiments."8.31FOXO1-miR-506 axis promotes chemosensitivity to temozolomide and suppresses invasiveness in glioblastoma through a feedback loop of FOXO1/miR-506/ETS1/FOXO1. ( Chen, C; Chen, J; Liu, Y; Shi, Y; Wang, H; Zhang, X, 2023)
"The cytotoxic effects of shikonin against murine glioblastoma cells, SB28 and CT-2A, were reported resistance to temozolomide, were evaluated using an allophycocyanin-conjugated annexin V and propidium iodide assay with flow cytometry."8.31Local administration of shikonin improved the overall survival in orthotopic murine glioblastoma models with temozolomide resistance. ( Maeoka, R; Matsuda, R; Morimoto, T; Nakagawa, I; Nakase, H; Nakazawa, T; Nishimura, F; Ouji, Y; Park, YS; Yamada, S; Yokoyama, S; Yoshikawa, M, 2023)
"To report the long-term outcomes in adult patients with grade 2 IDH-mutant astrocytoma treated with temozolomide (TMZ)-based chemoradiation."8.31Long-term treatment outcomes of temozolomide-based chemoradiation in patients with adult-type diffuse IDH-mutant grade 2 astrocytoma. ( Antonelli, M; Arcella, A; Bozzao, A; Capone, L; De Pietro, R; Esposito, V; Gianno, F; Giraffa, M; Lanzetta, G; Minniti, G; Paolini, S; Romano, A; Tini, P, 2023)
"In our previous study, we found for the first time that temozolomide (TMZ), the first-line chemotherapeutic agent for glioblastoma (GBM), can generate a large amount of reactive oxygen species (ROS) under ultrasound irradiation."8.31Temozolomide-based sonodynamic therapy induces immunogenic cell death in glioma. ( Jiao, J; Tong, X; Wen, B; Wu, Q; Xu, L; Yan, H; Yang, R; Zhou, Y, 2023)
"To investigate the effect of Temozolomide combined with intensity modulated radiation therapy on serum factor, immune function and clinical efficacy in postoperative glioma patients."8.31Effect of Temozolomide Combined with Intensity Modulated Radiation Therapy on Serum Factor, Immune Function and Clinical Efficacy in Postoperative Glioma Patients. ( Fan, R; Liu, J; Liu, Z; Yuan, J, 2023)
"Altogether, our results indicate that using nanoemulsion containing temozolomide in combination with ferrocene is an effective approach to improve glioblastoma therapy outcomes."8.31Development and characterization of a temozolomide-loaded nanoemulsion and the effect of ferrocene pre and co-treatments in glioblastoma cell models. ( Bernardes Ferro, M; da Rosa, RG; da Silva, LF; de Oliveira, JVR; de Souza, BM; Henn, JG; Lopes Alves, GA; Morás, AM; Moura, DJ; Nugent, M; Pires Peña, F; Rapack Jacinto Silva, V; Silva Pinheiro, AC; Silveira Aguirre, TA; Steffens Reinhardt, L, 2023)
"Temozolomide (TMZ) treatment efficacy in glioblastoma (GBM) patients has been limited by resistance in the clinic."8.31Albumin-bound paclitaxel augment temozolomide treatment sensitivity of glioblastoma cells by disrupting DNA damage repair and promoting ferroptosis. ( Huang, G; Li, Z; Qi, S; Qu, S; Wang, K; Ye, R; Yi, GZ; Zhang, H; Zhang, W; Zhu, T, 2023)
"To explore the mechanism through which curcumol reverses primary drug resistance in glioma cells."8.31[Curcumol reverses temozolomide resistance in glioma cells by regulating the UTX/MGMT axis]. ( Qian, Y; Sun, J; Tan, R; Tian, N; Xing, J, 2023)
"Chemotherapy using temozolomide is the standard treatment for patients with glioblastoma."8.31Genomic Exploration of Distinct Molecular Phenotypes Steering Temozolomide Resistance Development in Patient-Derived Glioblastoma Cells. ( Arijs, I; Beerens, C; Biswas, A; Byrne, AT; Chien, MP; Connor, K; Dilcan, G; Fabro, F; Feller, KJ; Idbaih, A; Kers, TV; Kremer, A; Lambrechts, D; Lamfers, MLM; Leenstra, S; Lodi, F; Ntafoulis, I; O'Farrell, AC; Prehn, JHM; Salvucci, M; Tching Chi Yen, R; Verreault, M, 2023)
"The standard treatment of glioblastoma patients consists of surgery followed by normofractionated radiotherapy (NFRT) with concomitant and adjuvant temozolomide chemotherapy."8.12Accelerated hyper-versus normofractionated radiochemotherapy with temozolomide in patients with glioblastoma: a multicenter retrospective analysis. ( Ehret, F; Grosu, AL; Kaul, D; Klement, RJ; Lewitzki, V; Polat, B; Popp, I; Sweeney, RA, 2022)
" With novel strategies focused on targeting hypoxia-inducible factor (HIF) regulatory pathways, recent evidence has shown that Acriflavine (ACF) can effectively target glioma invasiveness and recurrence."8.12Combined intracranial Acriflavine, temozolomide and radiation extends survival in a rat glioma model. ( Alomari, S; Brem, H; Cecia, A; Darjee, N; Domb, AJ; Gorelick, NL; Mangraviti, A; Rottenberg, Y; Serra, R; Shapira-Furman, T; Tyler, B, 2022)
"Resistance to temozolomide (TMZ) chemotherapy is the main reason for treatment failure in patients with glioblastoma (GBM)."8.12Biochanin A Sensitizes Glioblastoma to Temozolomide by Inhibiting Autophagy. ( Dong, Q; Duan, L; Li, L; Li, Q; Liu, Y; Pan, Y; Wang, D; Wang, J; Wang, X; Yin, H; Yuan, G, 2022)
"Nearly 10% of patients with adult diffuse glioma develop clinically significant myelotoxicity while on temozolomide (TMZ) leading to treatment interruptions."8.12Temozolomide-induced myelotoxicity and single nucleotide polymorphisms in the MGMT gene in patients with adult diffuse glioma: a single-institutional pharmacogenetic study. ( Chatterjee, A; Dasgupta, A; Epari, S; Gupta, T; Kota, PK; Kowtal, P; Moitra, P; Patil, V; Sarin, R, 2022)
"It is necessary to elucidate the individual effects of temozolomide (TMZ) on carcinogenesis and tumor resistance to chemotherapy mechanisms."8.12The Different Temozolomide Effects on Tumorigenesis Mechanisms of Pediatric Glioblastoma PBT24 and SF8628 Cell Tumor in CAM Model and on Cells In Vitro. ( Alonso, MM; Balnytė, I; Damanskienė, E; Preikšaitis, A; Stakišaitis, D; Valančiūtė, A, 2022)
"Temozolomide (TMZ) is a standard-of-care chemotherapeutic drug for the treatment of glioblastoma (GBM), but TMZ-acquired resistance limits its therapeutic effect."8.12Efficacy of Temozolomide-Conjugated Gold Nanoparticle Photothermal Therapy of Drug-Resistant Glioblastoma and Its Mechanism Study. ( Chu, L; Liu, X; Sha, C; Sun, K; Sun, Y; Wang, A; Wang, S; Xu, L; Yang, X; Yu, Y; Zhou, L, 2022)
"Temozolomide (TMZ) monotherapy is known to be insufficient for resistant/relapsed glioblastoma (GBM), thus seeking a sensitization agent for TMZ is necessary."8.12Regorafenib Reverses Temozolomide-Induced CXCL12/CXCR4 Signaling and Triggers Apoptosis Mechanism in Glioblastoma. ( Ali, AAA; Chiang, IT; Chou, SY; Hsu, FT; Hsu, TI; Liu, HS; Liu, YC, 2022)
"This retrospective study enrolled 65 patients with IDH wild-type recurrent glioblastoma who received standard therapy and then received either bevacizumab (46 patients) or temozolomide (19 patients) as a secondary treatment."8.12Contrast enhancing pattern on pre-treatment MRI predicts response to anti-angiogenic treatment in recurrent glioblastoma: comparison of bevacizumab and temozolomide treatment. ( Kim, HS; Kim, JH; Kim, YH; Moon, HH; Park, JE, 2022)
"Temozolomide (TMZ) is a first-line chemotherapeutic agent for the treatment of glioma."8.12The RNA-binding protein fragile-X mental retardation autosomal 1 (FXR1) modulates glioma cells sensitivity to temozolomide by regulating ferroptosis. ( Duan, S; Gong, F; Li, Q; Wei, Y, 2022)
"We retrospectively analyzed cytopenia during temozolomide-based concomitant radiochemotherapy in 492 patients with glioma."8.12Sex-Dependent Analysis of Temozolomide-Induced Myelosuppression and Effects on Survival in a Large Real-life Cohort of Patients With Glioma. ( Filipski, K; Filmann, N; Fokas, E; Forster, MT; Harter, PN; Herrlinger, U; Ronellenfitsch, MW; Steinbach, JP; Voss, M; Zeiner, PS, 2022)
" Temozolomide is widely used first-line chemotherapy drug to treat glioma patients, but development of temozolomide resistance is almost inevitable."8.12Inhibitory effects of temozolomide on glioma cells is sensitized by RSL3-induced ferroptosis but negatively correlated with expression of ferritin heavy chain 1 and ferritin light chain. ( Bian, XW; Cai, XW; Cao, MF; Gai, QJ; He, J; He, MM; Leng, P; Lu, HM; Mao, M; Qin, Y; Wang, C; Wang, Y; Wang, YX; Wen, XM; Yang, FC; Yao, XH; Yao, XX; Zhu, J, 2022)
" We herein investigate the therapeutic potential of bioinformatically identified HOTAIR transferred by serum-derived EVs (serum-EVs) in temozolomide (TMZ) resistance of glioblastoma (GBM) and the downstream mechanisms."8.12Serum-derived extracellular vesicles facilitate temozolomide resistance in glioblastoma through a HOTAIR-dependent mechanism. ( Han, J; Wang, S; Wang, X; Wang, Y; Wei, K; Xu, H; Yu, X, 2022)
"The aim of this study was to clarify whether PET with 11C-methyl-l-methionine (11C-met PET) can predict consequential outcomes at the time of discontinuing temozolomide (TMZ)-adjuvant chemotherapy in patients with residual isocitrate dehydrogenase gene (IDH)-mutant lower-grade glioma."8.12PET With 11C-Methyl-l-Methionine as a Predictor of Consequential Outcomes at the Time of Discontinuing Temozolomide-Adjuvant Chemotherapy in Patients With Residual IDH-Mutant Lower-Grade Glioma. ( Beppu, T; Fujiwara, S; Iwaya, T; Nomura, JI; Ogasawara, K; Sasaki, T; Sato, Y; Sugai, T; Terasaki, K; Yamada, N, 2022)
"Gliosarcoma is an uncommon glioblastoma subtype, for which MGMT promoter methylation's relationship with response to temozolomide chemotherapy is unclear."8.12Survival outcomes associated with MGMT promoter methylation and temozolomide in gliosarcoma patients. ( Iorgulescu, JB; Kavouridis, VK; Ligon, KL; Wen, PY, 2022)
"We sought to evaluate the effects of concurrent temozolomide-based chemoradiation therapy on neurocognitive function in patients with low-grade glioma (LGG)."8.12Cognitive function after concurrent temozolomide-based chemoradiation therapy in low-grade gliomas. ( Ahluwalia, MS; Angelov, L; Barnett, GH; Chao, ST; Chen, Y; Hogan, T; Kissel, C; Lapin, B; Mohammadi, A; Murphy, ES; Naugle, R; Park, DY; Parsons, MW; Peereboom, DM; Schuermeyer, I; Stevens, GHJ; Suh, JH; Tewari, S; Tom, MC; Yu, JS, 2022)
"Temozolomide (TMZ) is generally applied for glioma treatment, while drug resistance of TMZ limits its therapeutic efficacy."8.12Mannose inhibits proliferation and promotes apoptosis to enhance sensitivity of glioma cells to temozolomide through Wnt/β-catenin signaling pathway. ( Fei, YQ; Shi, RT; Song, Z; Wu, JZ; Zhou, YF, 2022)
"To study the relationship between temozolomide (TMZ) chemotherapy-resistant cells and stem cells in gliomas."8.12Preliminary Study on Relationship Between Temozolomide Chemotherapy-Resistant Cells and Stem Cells in Gliomas. ( Cunzu, W; Dingchao, X; Min, X; Xun, Z, 2022)
"To investigate the function of primary cilia in regulating the cellular response to temozolomide (TMZ) and ionizing radiation (IR) in glioblastoma (GBM)."8.12Inhibition of Ciliogenesis Enhances the Cellular Sensitivity to Temozolomide and Ionizing Radiation in Human Glioblastoma Cells. ( Cai, H; Gao, L; He, JP; Ma, W; Peng, SP; Tian, HB; Wang, JF; Wei, L, 2022)
"Glioblastoma multiforme (GBM) is an aggressive brain tumor, often occurring with seizures managed with antiepileptic drugs, such as levetiracetam (LEV)."8.12Association of plasma levetiracetam concentration, MGMT methylation and sex with survival of chemoradiotherapy-treated glioblastoma patients. ( Banchi, M; Bocci, G; Cucchiara, F; Danesi, R; Di Paolo, A; Giannini, N; Giorgi, FS; Luci, G; Orlandi, P; Pasqualetti, F, 2022)
"Temozolomide (TMZ) is the primary chemotherapeutic drug for treating glioblastoma (GBM); however, the final clinical outcome is considerably limited by the poor response and resistance to TMZ."8.12SOCS5 contributes to temozolomide resistance in glioblastoma by regulating Bcl-2-mediated autophagy. ( Han, L; Hu, L; Yang, F; Yu, J; Zhao, M; Zhou, H, 2022)
"Temozolomide (TMZ) is the first-line drug for the clinical treatment of glioblastoma (GBM), but drug resistance limits its treatment benefits."8.12Propofol enhances the sensitivity of glioblastoma cells to temozolomide by inhibiting macrophage activation in tumor microenvironment to down-regulate HIF-1α expression. ( Yun, K; Zhao, W, 2022)
"The mechanism by which glioblastoma evades temozolomide (TMZ)-induced cytotoxicity is largely unknown."8.12SH3GLB1-related autophagy mediates mitochondrial metabolism to acquire resistance against temozolomide in glioblastoma. ( Chang, KY; Chen, PY; Chen, SH; Cheng, SM; Chi, PI; Chien, CH; Chu, JM; Chuang, JY; Huang, CY; Hwang, DY; Lai, CC; Lee, JS; Liao, WA; Liu, CC; Wu, AC; Yang, ST; Yang, WB, 2022)
"Resistance to temozolomide (TMZ) is a major obstacle to preventing glioblastoma (GBM) recurrence after surgery."8.12PDIA3P1 promotes Temozolomide resistance in glioblastoma by inhibiting C/EBPβ degradation to facilitate proneural-to-mesenchymal transition. ( Deng, L; Fan, Y; Gao, Z; Guo, X; Li, G; Qi, Y; Sun, C; Wang, S; Xu, J; Xue, H; Zhang, P; Zhao, R; Zhao, S, 2022)
"Temozolomide (TMZ) resistance remains the main therapy challenge in patients with glioblastoma multiforme (GBM)."8.12TTK Protein Kinase promotes temozolomide resistance through inducing autophagy in glioblastoma. ( Gao, G; Wang, Y; Wei, X; Yu, J, 2022)
"We included 41 patients with isocitrate dehydrogenase 1/2-wildtype glioblastoma, who received 12 or more cycles of temozolomide therapy between June 2006 and December 2019."8.12Continuing maintenance temozolomide therapy beyond 12 cycles confers no clinical benefit over discontinuation at 12 cycles in patients with IDH1/2-wildtype glioblastoma. ( Miyakita, Y; Narita, Y; Ohno, M; Takahashi, M; Tamura, Y; Yanagisawa, S, 2022)
" Optical microscopy and flow cytometry were employed to assess the differences in glioblastoma cells morphology, proliferation, and cytotoxicity of anticancer drug temozolomide (TMZ) due to increased substrate viscosity."8.12Substrate viscosity impairs temozolomide-mediated inhibition of glioblastoma cells' growth. ( Bucki, R; Cieśluk, M; Kochanowicz, J; Kułakowska, A; Piktel, E; Pogoda, K; Skłodowski, K; Wnorowska, U, 2022)
" Temozolomide is the standard of care for gliomas, frequently results in resistance to drug and tumor recurrence."8.12Anticancer Effect of Cathelicidin LL-37, Protegrin PG-1, Nerve Growth Factor NGF, and Temozolomide: Impact on the Mitochondrial Metabolism, Clonogenic Potential, and Migration of Human U251 Glioma Cells. ( Alaverdian, DA; Buntovskaya, AS; Chernov, AN; Fedorov, EV; Filatenkova, TA; Galimova, ES; Glushakov, RI; Kim, AV; Matsko, MV; Shamova, OV; Skliar, SS; Tsapieva, AN, 2022)
"The DNA alkylating agent temozolomide (TMZ), is the first-line therapeutic for the treatment of glioblastoma (GBM)."8.12Potentiation of temozolomide activity against glioblastoma cells by aromatase inhibitor letrozole. ( DasGupta, B; Dave, N; Desai, JM; Desai, PB; Gudelsky, GA; Karve, AS; Phoenix, TN; Plas, DR; Sengupta, S; Wise-Draper, TM, 2022)
"The complex of formononetin and calycosin (FMN/CAL) shows a synergistic effect on temozolomide in the treatment of malignant glioma, however the mechanism is unclear."8.12The mechanism of formononetin/calycosin compound optimizing the effects of temozolomide on C6 malignant glioma based on metabolomics and network pharmacology. ( Fan, H; Fan, Y; Huang, T; Li, J; Li, S; Qiu, R; Zhang, Q; Zhou, Y, 2022)
"A MEX3A/CCR4-NOT/MSH2 axis plays a crucial role in promoting temozolomide resistance, providing new insights into the function of MEX3A and suggesting MEX3A as a potential therapeutic target in therapy-resistant glioblastoma."8.12MEX3A Impairs DNA Mismatch Repair Signaling and Mediates Acquired Temozolomide Resistance in Glioblastoma. ( Gan, T; Miao, F; Nie, E; Qian, X; Shen, Z; Shi, Q; Wang, P; Wang, Q; Wang, Y; Xie, M; Zhao, S, 2022)
"The role of temozolomide chemotherapy alone in isocitrate dehydrogenase (IDH)-mutant astrocytomas has not been conclusively determined."8.12Limited efficacy of temozolomide alone for astrocytoma, IDH-mutant, CNS WHO grades 2 or 3. ( Becker, H; Blobner, J; Egensperger, R; Katzendobler, S; Niyazi, M; Quach, S; Suchorska, B; Thiele, F; Thon, N; Tonn, JC; Weller, J; Weller, M, 2022)
"Systemic chemotherapy including monotherapy with temozolomide (TMZ) or bevacizumab (BEV); two-drug combinations, such as irinotecan (IRI) and BEV, TMZ and BEV and a three-drug combination with TMZ, IRI and BEV (TIB) have been used in treating patients with progressive high-grade gliomas including glioblastoma (GBM)."8.12Postmortem study of organ-specific toxicity in glioblastoma patients treated with a combination of temozolomide, irinotecan and bevacizumab. ( Ballester, LY; Bhattacharjee, MB; Brown, RE; Buja, LM; Chen, L; Glass, WF; Hergenroeder, GW; Hunter, RL; Linendoll, N; Lu, G; Pilichowska, M; Pillai, AK; Rao, M; Tian, X; Wu, JK; Zhang, R; Zhu, JJ; Zhu, P, 2022)
"Temozolomide (TMZ) resistance limits its use in glioblastoma (GBM)."8.12Hsa_circ_0043949 reinforces temozolomide resistance via upregulating oncogene ITGA1 axis in glioblastoma. ( Leng, H; Li, X; Wang, N; Xu, L; Yuan, H, 2022)
"Brain radiotherapy combined with concomitant and six cycles of adjuvant temozolomide (TMZ) is the standard treatment for newly diagnosed high-grade gliomas (HGGs)."8.12Standard or extended STUPP? Optimal duration of temozolomide for patients with high-grade gliomas: a retrospective analysis. ( Ai, P; Chen, J; He, L; Huang, Y; Li, R; Liu, Z; Pei, Y; Peng, X; Wang, J; Wei, Z; Zhao, F, 2022)
"Although temozolomide is the primary chemotherapeutic agent in glioblastoma, current studies have focused on its combinational applications to overcome resistance by targeting multiple pathways."8.12Ruxolitinib enhances cytotoxic and apoptotic effects of temozolomide on glioblastoma cells by regulating WNT signaling pathway-related genes. ( Biray Avci, C; Goker Bagca, B; Ozates, NP, 2022)
"It has been noted that temozolomide resistance occurs in a number of malignancies, including glioma, although the underlying cause of this is unknown."8.12CD147 Protein Expression and Temozolomide Resistance in Glioma Cells: An Ex vivo and In vivo Study. ( Bai, S; Chen, H; Fan, LL; Hu, Y; Luo, GQ; Yan, ZJ, 2022)
" The main cause is the presence of glioma stem cells (GSCs), exceptionally resistant to temozolomide (TMZ) treatment."8.12TRPML2 Mucolipin Channels Drive the Response of Glioma Stem Cells to Temozolomide and Affect the Overall Survival in Glioblastoma Patients. ( Amantini, C; Maggi, F; Morelli, MB; Nabissi, M; Pallini, R; Ricci-Vitiani, L; Santoni, G, 2022)
"It was found that radiotherapy combined with temozolomide administration often increased the size of the original lesion or produced a new glioblastoma lesion."8.12Apatinib combined with temozolomide treatment for pseudoprogression in glioblastoma: A case report. ( Cheng, P; Han, Q; Ma, H; Yang, H; Zhao, M; Zhao, Y, 2022)
"Thirty rats with glioma were divided into control group, temozolomide (TMZ) group (TMZ 30 mg/kg once daily for 5 day), and TMZ plus Caffeine group (TMZ 30 mg/kg once daily for 5 day and caffeine 100 mg/kg once daily for 2 weeks)."8.12Caffeine Inhibits Growth of Temozolomide-Treated Glioma via Increasing Autophagy and Apoptosis but Not via Modulating Hypoxia, Angiogenesis, or Endoplasmic Reticulum Stress in Rats. ( Chen, JC; Hwang, JH, 2022)
" Therefore, we aimed to examine the Synergistic effects of Gefitinib (GFI) in combination with Temozolomide on VEGF and MMPs in glioma cell line (U87MG)."8.12Synergistic Effect of Gefitinib and Temozolomide on U87MG Glioblastoma Angiogenesis. ( Hossienpour, M; Karami, A; Kiani, A; Mohammadi Noori, E; Najafi, K; Rahpyma, M, 2022)
"Glioma is the most frequent primary malignancy in the brain; temozolomide (TMZ) is the first-line chemotherapeutic agent used to combat this tumor."8.02AEG-1 silencing attenuates M2-polarization of glioma-associated microglia/macrophages and sensitizes glioma cells to temozolomide. ( Li, J; Ma, Y; Sun, X; Sun, Y; Wang, Y; Zhang, X; Zhao, X, 2021)
"Glioblastomas (GBM) often acquire resistance against temozolomide (TMZ) after continuous treatment and recur as TMZ-resistant GBM (TMZ-R-GBM)."8.02Lomustine and nimustine exert efficient antitumor effects against glioblastoma models with acquired temozolomide resistance. ( Fujii, T; Ichimura, K; Kawauchi, D; Kobayashi, T; Kondo, A; Nakano, T; Narita, Y; Sasaki, N; Satomi, K; Takahashi, M; Tomiyama, A; Uchida, E; Wada, K; Yamamuro, S; Yoshino, A, 2021)
" Here, we show that NSUN6 methylates both large and small RNA in glioblastoma and controls glioblastoma response to temozolomide with or without influence of the MGMT promoter status, with high NSUN6 expression conferring survival benefit to glioblastoma patients and in other cancers."8.02NSUN6, an RNA methyltransferase of 5-mC controls glioblastoma response to temozolomide (TMZ) via NELFB and RPS6KB2 interaction. ( Awah, CU; Mazdoom, CM; Ogunwobi, OO; Winter, J, 2021)
" CDC20 expression is increased in a variety of tumors and associated with temozolomide (TMZ) resistance in glioma cells."8.02Apcin inhibits the growth and invasion of glioblastoma cells and improves glioma sensitivity to temozolomide. ( Ding, Y; He, L; Pan, Y; Song, X; Yu, S; Zhang, C; Zheng, C, 2021)
"About 95% of Glioblastoma (GBM) patients experience tumor relapse as a consequence of resistance to the first-line standard chemotherapy using temozolomide (TMZ)."8.02Inhibition of Carbonic Anhydrase 2 Overcomes Temozolomide Resistance in Glioblastoma Cells. ( Bartsch, JW; Culmsee, C; Elsässer, K; Nimsky, C; Pagenstecher, A; Schäfer, A; Zhang, Z; Zhao, K; Zhong, L, 2021)
"To explore whether or not aberrant expression of miR-29b in glioblastoma multiforme (GBM) cells was associated with temozolomide (TMZ) resistance and to elucidate potential underlying mechanisms."8.02Micro-RNA29b enhances the sensitivity of glioblastoma multiforme cells to temozolomide by promoting autophagy. ( Luan, XP; Xu, JX; Yang, Y; Zhang, X, 2021)
"Temozolomide (TMZ) is widely used for glioma therapy in the clinic."8.02LncRNA MIR155HG Promotes Temozolomide Resistance by Activating the Wnt/β-Catenin Pathway Via Binding to PTBP1 in Glioma. ( He, X; Liu, Q; Sheng, J; Wang, K; Yu, W; Zhu, S, 2021)
"The study includes 132 IDH-wildtype glioblastoma patients treated between 2013 and 2017 with open resection followed by radiotherapy with concomitant and maintenance temozolomide."8.02Age-stratified clinical performance and survival of patients with IDH-wildtype glioblastoma homogeneously treated by radiotherapy with concomitant and maintenance temozolomide. ( Berger, K; Budach, W; Felsberg, J; Hänggi, D; Haussmann, J; Kamp, MA; Knipps, J; Malzkorn, B; Mijderwijk, HJ; Rapp, M; Reifenberger, G; Sabel, M; Steiger, HJ; Turowski, B, 2021)
"We report a case of acute interstitial nephritis with associated nephrogenic diabetes insipidus in a patient treated with temozolomide and sulfamethoxazole-trimethoprim for glioblastoma multiforme."8.02Acute interstitial nephritis and nephrogenic diabetes insipidus following treatment with sulfamethoxazole-trimethoprim and temozolomide. ( Athavale, A; Gallagher, M; Jardine, M; Morris, J; Ritchie, A; Sen, S; Wang, AY, 2021)
" Temozolomide is an oral DNA-alkylating agent capable of crossing the blood-brain barrier and used as chemotherapy primarily to treat glioblastoma and other brain cancers."8.02Central diabetes insipidus induced by temozolomide: A report of two cases. ( Capes, A; Duck, L; Duprez, T; Labriola, L; Mahiat, C; Whenham, N, 2021)
"Temozolomide (TMZ) is the major chemotherapy agent in glioma, and isocitrate dehydrogenase (IDH) is a well-known prognostic marker in glioma."8.02Identification of a three-long non-coding RNA signature for predicting survival of temozolomide-treated isocitrate dehydrogenase mutant low-grade gliomas. ( Chen, W; Jing, J; Li, R; Mao, P; Sun, Q; Wang, J; Wang, M; Yu, X, 2021)
"The purpose of this study is to clarify the clinical features of temozolomide (TMZ)-related hepatitis B virus (HBV) reactivation and to identify HBV reactivation predictive factors."8.02Hepatitis B virus reactivation during temozolomide administration for malignant glioma. ( Chonan, M; Inoue, J; Kanamori, M; Masamune, A; Osada, Y; Saito, R; Shimoda, Y; Shoji, T; Tominaga, T; Uenohara, H, 2021)
"8% of actual body weight calculated body surface area dosing was determined for concurrent phase temozolomide."8.02Actual body weight dosing of temozolomide and overall survival in patients with glioblastoma. ( Chambers, C; Coppens, R; de Robles, P; Dersch-Mills, D; Folkman, F; Ghosh, S; Hsu, PYH; Leckie, C, 2021)
"EORTC study 22033-26033 showed no difference in progression-free survival between high-risk low-grade glioma receiving either radiotherapy (RT) or temozolomide (TMZ) chemotherapy alone as primary treatment."8.02Memory in low-grade glioma patients treated with radiotherapy or temozolomide: a correlative analysis of EORTC study 22033-26033. ( Baumert, BG; Ben Hassel, M; Bromberg, JC; Drijver, AJ; Eekers, DBP; Freixa, SV; Golfinopoulos, V; Gorlia, T; Hoang-Xuan, K; Hottinger, AF; Klein, M; Lucas, A; Reijneveld, JC; Stupp, R; Taphoorn, MJB; Tzuk-Shina, T; van den Bent, MJ; Vauleon, E, 2021)
"Limited therapeutic efficacy of temozolomide (TMZ) against glioblastomas highlights the importance of exploring new drugs for clinical therapy."8.02Guanabenz Sensitizes Glioblastoma Cells to Sunitinib by Inhibiting GADD34-Mediated Autophagic Signaling. ( Chen, KC; Chen, PH; Cheng, CH; Ho, KH; Lee, YT; Shih, CM, 2021)
"Temozolomide (TMZ) is a first-line chemotherapy drug for the treatment of malignant glioma and resistance to it poses a major challenge."8.02Regulation of temozolomide resistance in glioma cells via the RIP2/NF-κB/MGMT pathway. ( Hu, YH; Jiao, BH; Wang, CY; Wu, JL, 2021)
" Temozolomide (TMZ) is widely used in the treatment of glioblastoma and is considered as the primary treatment modality."8.02Molecular biological investigation of temozolomide and KC7F2 combination in U87MG glioma cell line. ( Abbaszade, Z; Avci, CB; Bagca, BG, 2021)
" Treatment of patients suffering from relapsed/refractory glioblastoma (GBM) with a combination of depatux-m and temozolomide (TMZ) tended to increase overall survival."8.02Synergistic therapeutic benefit by combining the antibody drug conjugate, depatux-m with temozolomide in pre-clinical models of glioblastoma with overexpression of EGFR. ( Alvey, C; Anderson, M; Ansell, P; Boghaert, ER; Falls, HD; Mishra, S; Mitten, MJ; Oleksijew, A; Palma, J; Phillips, AC; Reilly, EB; Vaidya, KS; Zelaya-Lazo, AL, 2021)
"IDH-mutant anaplastic astrocytomas (AAs) are chemosensitive tumors for which the best choice of adjuvant chemotherapy between procarbazine, lomustine, and vincristine (PCV) or temozolomide (TMZ) after radiotherapy (RT) remains unclear."8.02Radiotherapy Plus Procarbazine, Lomustine, and Vincristine Versus Radiotherapy Plus Temozolomide for IDH-Mutant Anaplastic Astrocytoma: A Retrospective Multicenter Analysis of the French POLA Cohort. ( Bronniman, C; Carpentier, C; Ciron, DL; Dehais, C; Ducray, F; Esteyrie, V; Figarella-Branger, D; Martin, E; Moyal, EC; Network, P; Pouessel, D; Uro-Coste, E, 2021)
"Temozolomide (TMZ), an alkylating agent with a broad-spectrum antitumor activity, ability to cross blood-brain barrier (BBB), shown to be effective against malignant glioma."8.02Pharmacogenetics of ATP binding cassette transporter MDR1(1236C>T) gene polymorphism with glioma patients receiving Temozolomide-based chemoradiation therapy in Indian population. ( Baburaj, G; Jose, A; Kumar, JP; Munisamy, M; Munisamy, S; Subbiah, V; Thomas, L, 2021)
"Previous studies showed that the chemotherapeutic effect of temozolomide (TMZ) and vincristine (VCR) against glioma might be blunted by the co-culture with astrocytes, and connexin-43 (CX43) was thought to play a vital role in the communication between glioma cells and astrocytes."8.02AS602801 sensitizes glioma cells to temozolomide and vincristine by blocking gap junction communication between glioma cells and astrocytes. ( Fan, T; Fu, X; Gong, Y; Huang, Y; Li, Z; Wang, H; Xiang, P; Zhang, S, 2021)
" However, whether glioma stem cells (GSCs) can be sensitized to chemotherapy via combined treatment with temozolomide (TMZ) and nicardipine is unclear."8.02Nicardipine sensitizes temozolomide by inhibiting autophagy and promoting cell apoptosis in glioma stem cells. ( Dong, J; Dong, X; Jiang, Q; Li, H; Liu, L; Shi, J; Wang, H; Wang, L, 2021)
"To assess the recurrence interval and predictive significance of TP53 expression and O6-methylguanine-DNA methyltransferase (MGMT) promoter methylation in glioblastomas treated with radiotherapy and combined chemotherapies, including temozolomide, lomustine, procarbazine and bevacizumab."8.02Prognostic value of TP53 expression and MGMT methylation in glioblastoma patients treated with temozolomide combined with other chemotherapies. ( Alghamdi, B; Alkhayyat, S; Baeesa, S; Bardeesi, A; Bari, MO; Butt, NS; Dallol, A; Kurdi, M; Lary, AI; Maghrabi, Y; Mohamed, F; Saeedi, R; Samkari, A, 2021)
"Temozolomide (TMZ) is the internationally recognized and preferred drug for glioma chemotherapy treatment."8.02Hsa_circ_0110757 upregulates ITGA1 to facilitate temozolomide resistance in glioma by suppressing hsa-miR-1298-5p. ( Chen, Z; Li, H; Li, Y; Liu, Q; Su, J; Wu, M; Zhang, C, 2021)
"The alkylating agent, temozolomide (TMZ), is the most commonly used chemotherapeutic for the treatment of glioblastoma (GBM)."8.02CDK1 is up-regulated by temozolomide in an NF-κB dependent manner in glioblastoma. ( Arina, A; Bernal, GM; Cahill, KE; Campbell, PS; Crawley, CD; Mansour, N; Voce, DJ; Weichselbaum, RR; Wu, L; Yamini, B, 2021)
"Chemotherapy improves overall survival after surgery and radiotherapy for newly diagnosed high-risk IDH-mutant low-grade gliomas (LGGs), but a proportion of patients treated with temozolomide (TMZ) will develop recurrent tumors with TMZ-induced hypermutation."8.02Temozolomide-induced hypermutation is associated with distant recurrence and reduced survival after high-grade transformation of low-grade IDH-mutant gliomas. ( Berger, MS; Butowski, N; Chang, SM; Choi, S; Clarke, JL; Costello, JF; Grimmer, MR; Haas-Kogan, D; Hilz, S; Hong, C; Mazor, T; McDermott, M; Molinaro, AM; Oberheim Bush, NA; Phillips, JJ; Shai, A; Solomon, DA; Taylor, JW; Villanueva-Meyer, J; Wahl, M; Wainer, BH; Yu, Y, 2021)
" However, the alterations in gut microbiota observed during glioma growth and temozolomide (TMZ) therapy remain poorly understood."8.02Temozolomide-Induced Changes in Gut Microbial Composition in a Mouse Model of Brain Glioma. ( Jiang, Y; Jin, XQ; Li, J; Li, XC; Li, YR; Li, ZQ; Ma, C; Wang, ZF; Wu, BS; Yao, J, 2021)
"Our data revealed (i) a clinical association of the EMT-like process with glioma malignancy and a poor survival and (ii) an anticancer and temozolomide sensitizing effect of rabeprazole by repressing EMT."8.02Rabeprazole has efficacy per se and reduces resistance to temozolomide in glioma via EMT inhibition. ( Babu, D; Mudiraj, A; Panigrahi, M; Prakash Babu, P; Y B V K, C; Yadav, N, 2021)
"Temozolomide (TMZ) resistance limits its application in glioma."8.02Warburg effect-promoted exosomal circ_0072083 releasing up-regulates NANGO expression through multiple pathways and enhances temozolomide resistance in glioma. ( Bu, X; Chen, X; Ding, C; Gu, J; Kang, D; Lin, Y; Lin, Z; Sun, Y; Wu, X; Wu, Z; Yi, X; You, H; Zhang, G, 2021)
" This study investigated whether the improved oxygenation and perfusion that has been previously observed with RRx-001 both preclinically and clinically in the context of a brain metastasis trial was correlated with increased penetration and accumulation of the cytotoxic chemotherapies, irinotecan and temozolomide, in orthotopically implanted gliomas, priming tumours for improved response."8.02Vascular priming with RRx-001 to increase the uptake and accumulation of temozolomide and irinotecan in orthotopically implanted gliomas. ( Cabrales, P; Oronsky, B; Reid, T, 2021)
"Temozolomide (TMZ) resistance is the main challenge in the management of glioma patients."8.02Heparanase confers temozolomide resistance by regulation of exosome secretion and circular RNA composition in glioma. ( Cao, L; Chen, Z; Jiang, Z; Li, W; Li, X; Si, J, 2021)
"To clarify whether differential compartmentalization of Survivin impacts temozolomide (TMZ)-triggered end points, we established a well-defined glioblastoma cell model in vitro (LN229 and A172) and in vivo, distinguishing between its nuclear and cytoplasmic localization."8.02Localization matters: nuclear-trapped Survivin sensitizes glioblastoma cells to temozolomide by elevating cellular senescence and impairing homologous recombination. ( Baymaz, HI; Beli, P; Christmann, M; Mühlhäusler, F; Nikolova, T; Poplawski, A; Reich, TR; Schwarzenbach, C; Tomicic, MT; Unger, S; Vilar, JB, 2021)
"Glioblastoma multiforme (GBM) is the most fatal cancer among brain tumors, and the standard treatment of GBM patients is surgical tumor resection followed by radiotherapy and temozolomide (TMZ) chemotherapy."8.0217β-estradiol induces temozolomide resistance through NRF2-mediated redox homeostasis in glioblastoma. ( Chen, GY; Hsu, SP; Hsu, TI; Hung, CY; Ko, CY; Liao, KH; Lin, HY, 2021)
"Following captopril treatment, MMP-2 protein expression and migratory capabilities of 9 L gliosarcoma cells were assessed in vitro via western blots and scratch wound assays, respectively."8.02Captopril inhibits Matrix Metalloproteinase-2 and extends survival as a temozolomide adjuvant in an intracranial gliosarcoma model. ( Brem, H; Casaos, J; Huq, S; Mangraviti, A; Paldor, I; Perdomo-Pantoja, A; Pinheiro, L; Tyler, B; Vigilar, V; Wang, Y; Witham, TF, 2021)
"To report clinical outcomes of temozolomide (TMZ)-based radio-chemotherapy and adjuvant chemotherapy in patients with aggressive/high-risk low-grade glioma (LGG)."8.02Upfront Therapy of Aggressive/High-Risk Low-Grade Glioma: Single-Institution Outcome Analysis of Temozolomide-Based Radio-Chemotherapy and Adjuvant Chemotherapy. ( Anand, S; Chatterjee, A; Epari, S; Goda, JS; Gupta, T; Jalali, R; Krishnatry, R; Moiyadi, A; Panda, P; Patil, V, 2021)
"A maximal surgical resection followed by radiotherapy and chemotherapy with temozolomide (TMZ) as the representative agent is the standard therapy for gliomas."8.02The function and mechanism of the JARID2/CCND1 axis in modulating glioma cell growth and sensitivity to temozolomide (TMZ). ( Chen, Y; Jiang, W; Kuang, W; Liu, Z; Tian, Y, 2021)
"Apatinib and TMZ may represent an alternative treatment option for patients with recurrent high-gradeglioma, especially those with a low Karnofsky performance status."8.02Clinical study of apatinib plus temozolomide for the treatment of recurrent high-grade gliomas. ( Feng, M; Gan, W; Huang, Y; Li, X; Liu, J; Shao, Y; Wang, X; Yao, H; Zhang, C; Zhou, Y, 2021)
"Intrinsic or acquired resistance to temozolomide (TMZ) is a frequent occurrence in patients with glioblastoma (GBM)."8.02Exosomal transfer of miR‑25‑3p promotes the proliferation and temozolomide resistance of glioblastoma cells by targeting FBXW7. ( Li, T; Wang, B; Wang, J, 2021)
"To evaluate the predictive significance of the duration of temozolomide (TMZ) in patients with glioblastoma multiforme (GBM) who were treated with bevacizumab (Beva) as second-line setting."8.02Is the Duration of Temozolomide Predictive for Sequential Bevacizumab Treatment Responses in the Glioblastoma Multiforme Cancer Setting? ( Besiroglu, M; Demir, T; Shbair, ATM; Topcu, A; Turk, HM; Yasin, AI, 2021)
" We investigated the effects of dopamine in combination with platinum on human glioblastoma U-251MG cells upon X-ray irradiation, comparing with L-DOPA, 2-phenylethylamine and temozolomide."8.02Effects of platinum-coexisting dopamine with X-ray irradiation upon human glioblastoma cell proliferation. ( Kato, S, 2021)
"Improving the chemotherapy resistance of temozolomide (TMZ) is of great significance in the treatment of glioblastoma multiforme (GBM)."8.02Long noncoding RNA just proximal to X-inactive specific transcript facilitates aerobic glycolysis and temozolomide chemoresistance by promoting stability of PDK1 mRNA in an m6A-dependent manner in glioblastoma multiforme cells. ( Jiang, XB; Li, XD; Wang, MJ; Wang, X; Wu, YH; Zheng, JL, 2021)
"Standard treatment for glioblastoma (GBM) patients is surgery and radiochemotherapy (RCT) with temozolomide (TMZ)."7.96ABCB1 single-nucleotide variants and survival in patients with glioblastoma treated with radiotherapy concomitant with temozolomide. ( Åkesson, L; Bratthäll, C; Broholm, H; Fomichov, V; Green, H; Grunnet, K; Hallbeck, M; Jakobsen, I; Malmström, A; Milos, P; Mudaisi, M; Papagiannopoulou, A; Poulsen, HS; Söderkvist, P; Stenmark-Askmalm, M; Strandeus, M; Łysiak, M, 2020)
"Temozolomide (TMZ) is one of the most common drugs selected for glioma chemotherapy, but the therapeutic effect of glioma treatment is usually limited due to its resistance."7.96LINC00174 down-regulation decreases chemoresistance to temozolomide in human glioma cells by regulating miR-138-5p/SOX9 axis. ( Chen, M; Li, B; Song, J; Wang, F; Zhao, H, 2020)
"Temozolomide is a first line anti-tumor drug used for the treatment of patients with Glioblastoma multiforme (GBM)."7.96Microarray expression profiles and bioinformatics analysis of mRNAs, lncRNAs, and circRNAs in the secondary temozolomide-resistant glioblastoma. ( Gao, Y; Guo, R; Li, H; Yang, B; Zhao, C, 2020)
"In the EF-14 trial for newly diagnosed glioblastoma (ndGBM) patients addition of Tumour Treating Fields (TTFields) to temozolomide treatment resulted in a significantly improved overall survival (OS)."7.96Tumour Treating Fields (TTFields) in combination with lomustine and temozolomide in patients with newly diagnosed glioblastoma. ( Blau, T; Deuschl, C; Glas, M; Herrlinger, U; Kebir, S; Keyvani, K; Kleinschnitz, C; Lazaridis, L; Oster, C; Pierscianek, D; Schäfer, N; Scheffler, B; Schmidt, T; Stuschke, M; Sure, U; Teuber-Hanselmann, S; Tzaridis, T; Weller, J, 2020)
"This analysis aimed to investigate whether the long-term administration of temozolomide (TMZ) claimed a survival advantage for patients with glioblastoma in China."7.96Survival analysis of patients with glioblastoma treated by long-term administration of temozolomide. ( Li, X; Li, Z; Quan, R; Zhang, H, 2020)
" Here, we detail anti-PD-L1 antibody effects on the tumor microenvironment, including Mϕ infiltration, using a temozolomide (TMZ)-treated glioma model."7.96Infiltration of CD163-positive macrophages in glioma tissues after treatment with anti-PD-L1 antibody and role of PI3Kγ inhibitor as a combination therapy with anti-PD-L1 antibody in in vivo model using temozolomide-resistant murine glioma-initiating cell ( Akutsu, H; Ishikawa, E; Kohzuki, H; Matsuda, M; Matsumura, A; Miyazaki, T; Sakamoto, N; Sugii, N; Takano, S, 2020)
"Chemo-induced thrombocytopenia is a limiting toxicity among patients receiving temozolomide (TMZ) as first-line treatment for glioblastoma."7.96Deleterious impact of a generic temozolomide formulation compared with brand-name product on the kinetic of platelet concentration and survival in newly diagnosed glioblastoma. ( Alexandru, C; Basuyau, F; Clatot, F; Di Fiore, F; Fontanilles, A; Fontanilles, M; Hanzen, C; Joannidès, R; Lamoureux, F; Langlois, O; Massy, N; Pereira, T; Rouvet, J; Tennevet, I, 2020)
"The isocitrate dehydrogenase (IDH) 1 wild-type glioblastoma (GBM) is a major population of GBM that should be of concern in terms of the efficacy of using Temozolomide (TMZ) in adjuvant treatment."7.96Temozolomide for patients with wild-type isocitrate dehydrogenase (IDH) 1 glioblastoma using propensity score matching. ( Sangkhathat, S; Tunthanathip, T, 2020)
"This is the long-term update of NOA-08 (NCT01502241), which compared efficacy and safety of radiotherapy (RT, n = 176) and temozolomide (TMZ, n = 193) at 7/14 days in patients >65 years old with anaplastic astrocytoma or glioblastoma."7.96Superiority of temozolomide over radiotherapy for elderly patients with RTK II methylation class, MGMT promoter methylated malignant astrocytoma. ( Bamberg, M; Bölting, H; Debus, J; Felsberg, J; Herrlinger, U; Hertler, C; Kessler, T; Ketter, R; Mayer-Steinacker, R; Meisner, C; Meixensberger, J; Papsdorf, K; Platten, M; Reifenberger, G; Reuss, D; Sabel, M; Sahm, F; Steinbach, JP; Vesper, J; von Deimling, A; Weisang, S; Weller, M; Weyerbrock, A; Wick, A; Wick, W, 2020)
"Temozolomide (TMZ) is a drug of choice in glioblastoma treatment."7.96Revealing the epigenetic effect of temozolomide on glioblastoma cell lines in therapeutic conditions. ( Barciszewska, AM; Barciszewski, J; Belter, A, 2020)
"Glioblastoma multiforme (GBM) is the most frequent primary brain tumor in adults and Temozolomide (TMZ) is an effective chemotherapeutic agent for its treatment."7.96Reinforcement learning for optimal scheduling of Glioblastoma treatment with Temozolomide. ( Ebrahimi Zade, A; Shahabi Haghighi, S; Soltani, M, 2020)
"Temozolomide (TMZ) resistance is a major cause of recurrence and poor prognosis in glioblastoma (GBM)."7.96LncRNA SOX2OT promotes temozolomide resistance by elevating SOX2 expression via ALKBH5-mediated epigenetic regulation in glioblastoma. ( Chi, Y; Fu, Z; Guo, H; Huang, Q; Lian, C; Liao, C; Liu, B; Wang, C; Wei, Q; Xu, N; Yang, Z; Zeng, H; Zhou, J, 2020)
"To some extent, Si wei xiao xiu yin combined with temozolomide can inhibit the growth of subcutaneous xenografts in glioma nude mice."7.96New advances on the inhibition of Siwei Xiaoliuyin combined with Temozolomide in glioma based on the regulatory mechanism of miRNA21/221. ( Chen, H; Chen, Y; Li, C; Sharma, A; Sharma, HS; Tan, Q; Xie, C; Yang, Y; Zhan, W; Zhang, Z, 2020)
"Temozolomide (TMZ) chemotherapy is a current standard of care for glioblastoma (GBM), however it has only extended overall survival by a few months."7.96Temozolomide antagonizes oncolytic immunovirotherapy in glioblastoma. ( Martuza, RL; Rabkin, SD; Saha, D, 2020)
"Temozolomide is a first line anti-tumor drug used for the treatment of patients with Glioblastoma multiforme (GBM)."7.96MicroRNA-128-3p Enhances the Chemosensitivity of Temozolomide in Glioblastoma by Targeting c-Met and EMT. ( Guan, F; Guo, R; Li, H; Li, M; Liu, X; Ma, S; Wu, J; Yang, B; Zhao, C, 2020)
"Temozolomide (TMZ) is a DNA-alkylating agent used for chemo-radiotherapy of glioblastoma, which is also a target cancer for boron neutron capture therapy (BNCT)."7.96The combined effect of neutron irradiation and temozolomide on glioblastoma cell lines with different MGMT and P53 status. ( Ikawa, T; Kinashi, Y; Takahashi, S, 2020)
"To evaluate the potential prognostic utility of pretreatment systemic immune-inflammation index (SII) in newly diagnosed glioblastoma multiforme (GBM) patients who underwent postneurosurgical radiotherapy and concurrent plus adjuvant temozolomide."7.96Prognostic Value of Pretreatment Systemic Immune-Inflammation Index in Glioblastoma Multiforme Patients Undergoing Postneurosurgical Radiotherapy Plus Concurrent and Adjuvant Temozolomide. ( Besen, AA; Kucuk, A; Mertsoylu, H; Ozdemir, Y; Pehlivan, B; Selek, U; Topkan, E, 2020)
"5, 1 g/kg) or temozolomide (10 mg/kg) treatment alone inhibited tumor growth in glioblastoma U87 and U251 xenografts."7.96Xihuang pill potentiates the anti-tumor effects of temozolomide in glioblastoma xenografts through the Akt/mTOR-dependent pathway. ( Fu, J; Kong, PS; Wang, J; Wang, X; Xu, HB; Xu, YQ; Zhu, SH, 2020)
"Temozolomide (TMZ) is a chemotherapeutic used for the treatment of glioblastoma."7.96A co-formulation of interferons type I and II enhances temozolomide response in glioblastoma with unmethylated MGMT promoter status. ( Bello-Rivero, I; Leenstra, S; van der Kaaij, M; Vázquez-Blomquist, D; Villarreal, A, 2020)
"We designed a conjugated compound by coupling temozolomide (TMZ) with doxorubicin (DOX) via an acylhydrazone linkage as a potential prodrug used for glioblastoma multiforme (GBM) treatment."7.96Temozolomide-Doxorubicin Conjugate as a Double Intercalating Agent and Delivery by Apoferritin for Glioblastoma Chemotherapy. ( Du, K; Feng, F; Heng, H; Xia, Q, 2020)
"Resistance of glioblastoma to the chemotherapeutic compound temozolomide is associated with the presence of glioblastoma stem cells in glioblastoma and is a key obstacle for the poor prognosis of glioblastoma."7.96Phospholipase D1 inhibition sensitizes glioblastoma to temozolomide and suppresses its tumorigenicity. ( Hwang, WC; Kang, DW; Min, DS; Noh, YN; Park, KS, 2020)
"Temozolomide is the most effective chemotherapy for malignant glioma."7.96Temozolomide desensitization followed by metronomic dosing in patients with hypersensitivity. ( Divekar, RD; Johnson, DR; Maddox, DE; Neth, BJ; Ruff, MW; Uhm, JH, 2020)
"Temozolomide (TMZ) therapy is the standard of care for patients with glioblastoma (GBM)."7.96Preconditioning with INC280 and LDK378 drugs sensitizes MGMT-unmethylated glioblastoma to temozolomide: Pre-clinical assessment. ( Alshareef, M; Cachia, D; Das, A; Infinger, LK; Lindhorst, SM; Patel, SJ; Porto, GBF; Vandergrift, WA; Varma, AK, 2020)
" Concurrent temozolomide (TMZ) radiation-the cornerstone of glioma control-extends the overall median survival of GB patients by only a few months over radiotherapy alone."7.96Developing a clinically relevant radiosensitizer for temozolomide-resistant gliomas. ( Chen, TC; Cho, HY; Duc, TC; Hartman, H; Hofman, FM; Huang, M; Minea, RO; Schönthal, AH; Swenson, SD, 2020)
" In glioblastoma (GBM), predictive biomarkers of cellular responses to temozolomide (TMZ) combined with poly‑ADP‑ribose polymerase inhibitor (PARPi) remain largely unidentified."7.96PARP‑1 inhibition sensitizes temozolomide‑treated glioblastoma cell lines and decreases drug resistance independent of MGMT activity and PTEN proficiency. ( Godoy, PRDV; Lima, SCG; Montaldi, AP; Sakamoto-Hojo, ET; Xavier, DJ, 2020)
" The transfection efficiency was determined with flow cytometry, and the therapeutic efficacy of CD::UPRT::GFP expressing MSCs was evaluated in cocultures with temozolomide (TMZ)-sensitive or TMZ-resistant human glioblastoma cell lines."7.96A facile and scalable in production non-viral gene engineered mesenchymal stem cells for effective suppression of temozolomide-resistant (TMZR) glioblastoma growth. ( Ho, YK; Ng, ZX; Teo, KJ; Too, HP; Tu, GXE; Yeo, TT, 2020)
"To assess the patterns of failure and prognostic factors in Brazilian patients with glioblastoma multiforme (GBM) treated with radiotherapy (RT) and concurrent and adjuvant temozolomide (TMZ)."7.96Patterns of recurrence and outcomes of glioblastoma multiforme treated with chemoradiation and adjuvant temozolomide. ( Faustino, AC; Hamamura, AC; Viani, GA, 2020)
" In this study, we explore whether CAP, an ionized gas produced in laboratory settings and that operates at near room temperature, can enhance Temozolomide (TMZ) cytotoxicity on a glioblastoma cell line (U87MG)."7.96Combination therapy of cold atmospheric plasma (CAP) with temozolomide in the treatment of U87MG glioblastoma cells. ( Gjika, E; Keidar, M; Kirschner, ME; Lin, L; Pal-Ghosh, S; Sherman, JH; Stepp, MA, 2020)
"Glioma, especially glioblastoma (GBM), is the most aggressive malignant brain tumor and its standard therapy is often ineffective because of temozolomide (TMZ) resistance."7.96Combination of levetiracetam and IFN-α increased temozolomide efficacy in MGMT-positive glioma. ( Cai, HP; Chen, FR; Chen, ZP; Guo, CC; Ma, JX; Ni, XR; Wang, J; Wu, WC; Yu, YJ; Yu, ZH, 2020)
"Despite aggressive treatment with temozolomide and radiotherapy and extensive research into alternative therapies there has been little improvement in Glioblastoma patient survival."7.96Reduced EGFR and increased miR-221 is associated with increased resistance to temozolomide and radiotherapy in glioblastoma. ( Areeb, Z; Gomez, J; Jones, J; Kaye, AH; Luwor, RB; Morokoff, AP; Nguyen, HPT; Paradiso, L; Stuart, SF; West, AJ; Zulkifli, A, 2020)
"Glioblastoma (GBM) is a malignant brain tumour with a dismal prognosis, despite best treatment by surgical resection, radiation therapy (RT) and chemotherapy with temozolomide (TMZ)."7.96Cytotoxic lanthanum oxide nanoparticles sensitize glioblastoma cells to radiation therapy and temozolomide: an in vitro rationale for translational studies. ( Jue, TR; Lu, VM; McDonald, KL, 2020)
"Objective To investigate the expression of cathepsin S (CTSS) in temozolomide-resistant glioblastoma T98G (T98G-R) cells."7.96[Cathepsin S (CTSS) is highly expressed in temozolomide-resistant glioblastoma T98G cells and associated with poor prognosis]. ( Guo, Q; Jia, B; Liu, W; Lyu, W, 2020)
" However, the function of circ_0005198 in the temozolomide (TMZ) resistance of glioma has not been well elucidated."7.96Circ_0005198 enhances temozolomide resistance of glioma cells through miR-198/TRIM14 axis. ( Deng, Y; Liu, C; Meng, X; Xiao, L; Zhu, H, 2020)
" In this study, we investigated whether selective add-on BEV for patients with newly diagnosed glioblastoma (GBM) and anaplastic astrocytoma (AA) improves prognosis, in cases where tumors were continuously growing during radiotherapy concomitant with temozolomide (TMZ)."7.96The prognostic improvement of add-on bevacizumab for progressive disease during concomitant temozolomide and radiation therapy in patients with glioblastoma and anaplastic astrocytoma. ( Hirata, K; Houkin, K; Ishi, Y; Kobayashi, H; Motegi, H; Oda, Y; Okamoto, M; Tanaka, S; Terasaka, S; Yamaguchi, S, 2020)
"The natural product primary sulfonamide, psammaplin C (1), when used in combination with clinically used chemotherapeutic drugs, including temozolomide, reverses multidrug resistance and increases survival in glioblastoma, a highly aggressive primary brain tumor."7.91Carbonic Anhydrase XII Inhibitors Overcome Temozolomide Resistance in Glioblastoma. ( Bua, S; Kopecka, J; Mujumdar, P; Poulsen, SA; Riganti, C; Supuran, CT, 2019)
"Temozolomide (TMZ) is a first-line chemotherapeutic agent used against glioblastoma multiforme (GBM), but this disease exhibits recurrence and high lethality."7.91miR-140 targeting CTSB signaling suppresses the mesenchymal transition and enhances temozolomide cytotoxicity in glioblastoma multiforme. ( Chen, KC; Chen, PH; Cheng, CH; Chou, CM; Ho, KH; Lin, CW; Liu, AJ; Shih, CM, 2019)
"Our study elucidated the role of oncogenic LINC01198 in glioma proliferation and temozolomide resistance, and this role may serve as a promising target for glioma therapy."7.91LINC01198 promotes proliferation and temozolomide resistance in a NEDD4-1-dependent manner, repressing PTEN expression in glioma. ( Chen, HJ; Chen, WL; Ge, JW; Hou, GQ; Zhang, XH, 2019)
" In this study, we investigate the underlying mechanism by which glioblastoma (GBM) cells acquire resistance to Temozolomide (TMZ) through Aurora kinase B (AURKB) thus to identify novel therapeutic targets and prognostic biomarkers for GBM."7.91Targeting Aurora kinase B attenuates chemoresistance in glioblastoma via a synergistic manner with temozolomide. ( Alafate, W; Liu, C; Sun, L; Wang, J; Wang, M; Wu, W; Xie, W; Zuo, J, 2019)
" However, the role of circular RNA CEP128 in the resistance of glioma cells to temozolomide has not yet been characterized."7.91Knockdown of circular RNA CEP128 suppresses proliferation and improves cytotoxic efficacy of temozolomide in glioma cells by regulating miR-145-5p. ( Feng, H; Hua, L; Huang, L; Shen, B; Zhang, X, 2019)
"To investigate the underlying mechanism by which glioblastoma (GBM) cells gain temozolomide (TMZ) resistance and to clarify novel therapeutic targets and new prognostic biomarkers for GBM."7.91Nuclear factor I A promotes temozolomide resistance in glioblastoma via activation of nuclear factor κB pathway. ( Li, R; Mao, P; Wahafu, A; Wang, J; Wang, M; Wu, W; Xie, W; Yu, X; Zuo, J, 2019)
"Current treatment of recurrent glioblastoma multiforme (GBM) demands dose-intense temozolomide (TMZ), a prodrug of 5-(3-methyltriazen-1-yl) imidazole-4-carboxamide (MTIC), based on the spontaneous hydrolysis of TMZ at basic pH."7.91Enhanced Copper-Temozolomide Interactions by Protein for Chemotherapy against Glioblastoma Multiforme. ( Du, K; Feng, F; Li, X; Shao, F; Sun, J; Sun, Y, 2019)
"Drug resistance to temozolomide (TMZ) contributes to the majority of tumor recurrence and treatment failure in patients with glioblastoma multiforme (GBM)."7.91Lovastatin Enhances Cytotoxicity of Temozolomide via Impairing Autophagic Flux in Glioblastoma Cells. ( Cheng, SY; Kiang, KMY; Leung, GK; Li, N; Wong, VK; Zhang, P; Zhu, Z, 2019)
"The purpose of this study was to evaluate the outcomes of elderly patients (aged ≥75 years) with newly diagnosed glioblastoma (GBM), who were treated with hypofractionated radiotherapy comprising 45 Gy in 15 fractions combined with temozolomide (TMZ) or TMZ and bevacizumab (TMZ/Bev)."7.91Survival benefits of hypofractionated radiotherapy combined with temozolomide or temozolomide plus bevacizumab in elderly patients with glioblastoma aged ≥ 75 years. ( Ichimura, K; Igaki, H; Matsushita, Y; Miyakita, Y; Narita, Y; Ohno, M; Takahashi, M, 2019)
"Temozolomide (TMZ) is the most commonly used chemotherapeutic agent used to treat glioblastoma (GBM), which causes significant DNA damage to highly proliferative cells."7.91Inhibition of phosphatidylinositol 3-kinase by PX-866 suppresses temozolomide-induced autophagy and promotes apoptosis in glioblastoma cells. ( Harder, BG; Kitange, GJ; Loftus, JC; Peng, S; Sarkaria, JN; Sereduk, CP; Sodoma, AM; Tran, NL, 2019)
"In the management of patients with newly diagnosed glioblastoma, there is no standard duration for adjuvant temozolomide treatment."7.91Feasibility study of finalizing the extended adjuvant temozolomide based on methionine positron emission tomography (Met-PET) findings in patients with glioblastoma. ( Hasegawa, Y; Hatano, K; Hirono, S; Iuchi, T; Sakaida, T; Uchino, Y, 2019)
"Bortezomib was found to inhibit glioma growth and improved TMZ chemotherapy efficacy, probably via down-regulating the FOXM1-Survivin axis."7.91Bortezomib inhibits growth and sensitizes glioma to temozolomide (TMZ) via down-regulating the FOXM1-Survivin axis. ( Chen, JX; Du, L; Huang, GH; Li, QR; Lv, SQ; Tang, JH; Xiang, Y; Xu, QF; Yang, L; Zhang, ZX; Zhou, Z; Zhu, LR, 2019)
"Current standard of treatment for newly diagnosed patients with glioblastoma (GBM) is surgical resection with adjuvant normofractionated radiotherapy (NFRT) combined with temozolomide (TMZ) chemotherapy."7.91Accelerated hyperfractionated radiochemotherapy with temozolomide is equivalent to normofractionated radiochemotherapy in a retrospective analysis of patients with glioblastoma. ( Flentje, M; Klement, RJ; Kosmala, R; Lewitzki, V; Lisowski, D; Polat, B, 2019)
"Temozolomide (TMZ) is known to induce thrombocytopenia but no early predictive test has yet been clearly established."7.91Early platelet variation during concomitant chemo-radiotherapy predicts adjuvant temozolomide-induced thrombocytopenia in newly diagnosed glioblastoma patients. ( Alexandru, C; Clatot, F; David, M; Di Fiore, F; Fontanilles, M; Gilard, V; Hanzen, C; Langlois, O; Laquerriere, A; Marguet, F; Tennevet, I; Veresezan, O, 2019)
"Glioblastoma multiforme (GBM) has a poor prognosis with an overall survival of 14-15 months after surgery, radiation and chemotherapy using temozolomide (TMZ)."7.91Thioridazine inhibits autophagy and sensitizes glioblastoma cells to temozolomide. ( Bjerkvig, R; Denisova, O; Grudic, A; Hasan-Olive, MM; Janji, B; Johannessen, TC; Latif, MA; Lund-Johansen, M; Nordal, A; Prestegarden, L; Røsland, GV; Saed, H; Simonsen, A; Sundstrøm, T; Tronstad, KJ; Varughese, JK; Wang, J; Westermarck, J; Yang, N; Zhu, H, 2019)
"To describe oncological patterns of care, prognostic factors, and survival for all patients in France with newly-diagnosed and histologically confirmed glioblastoma, and evaluate the impact of extended temozolomide use at the population level."7.91Association of patterns of care, prognostic factors, and use of radiotherapy-temozolomide therapy with survival in patients with newly diagnosed glioblastoma: a French national population-based study. ( Amelot, A; Bauchet, F; Bauchet, L; Bessaoud, F; Charissoux, M; Darlix, A; Duffau, H; Fabbro, M; Fabbro-Peray, P; Figarella-Branger, D; Mandonnet, E; Mathieu-Daude, H; Pallud, J; Rigau, V; Riondel, A; Sorbets, E; Taillandier, L; Tretarre, B; Zouaoui, S, 2019)
"Despite the clinical success of temozolomide (TMZ), its sensitivity remains a major challenge in glioblastoma (GBM)."7.91PLK4 is a determinant of temozolomide sensitivity through phosphorylation of IKBKE in glioblastoma. ( Han, L; Huang, K; Liang, H; Liu, Y; Wang, G; Wang, Q; Wang, Z; Wei, C; Zhang, A; Zhang, W; Zhang, Z; Zhen, Y; Zhou, J, 2019)
"Chemotherapy is the main postsurgical and adjuvant therapy for glioma, and intrinsic or acquired temozolomide (TMZ) resistance may result in poor prognosis."7.91MiR-181b-5p modulates chemosensitivity of glioma cells to temozolomide by targeting Bcl-2. ( Feng, B; Ren, H; Wang, J; Yu, J; Yuan, Z; Zhang, B; Zhang, X; Zhao, C; Zhuang, J, 2019)
"For our studies, we have particularly chosen C6 rat glioma cell line due to several reasons: i) We previously showed that MPA reduced growth and induced procarbazine-sensitization in C6 cells; ii) temozolomide has a triazene-type molecular structure like procarbazine; iii) other groups previously showed that C6 glioma cell line is more resistant to temozolomide than human glioma cells; hence it may provide a native model of chemoresistance."7.91Medroxyprogesterone effects on colony growth, autophagy and mitochondria of C6 glioma cells are augmented with tibolone and temozolomide: Cell kinetic and electron microscopical studies with a broad review of the literature. ( Altinoz, MA; Bilir, A; Elmaci, İ; Ozpinar, A, 2019)
"Chemotherapy with temozolomide (TMZ) is the traditional treatment for glioblastoma (GBM)."7.91MCCK1 enhances the anticancer effect of temozolomide in attenuating the invasion, migration and epithelial-mesenchymal transition of glioblastoma cells in vitro and in vivo. ( Li, A; Liu, T; Xin, Y; Xu, Y, 2019)
"Temozolomide (TMZ) is a widely used chemotherapeutic agent for glioblastoma multiforme (GBM)."7.91Momelotinib sensitizes glioblastoma cells to temozolomide by enhancement of autophagy via JAK2/STAT3 inhibition. ( Li, A; Liu, T; Xin, Y; Xu, Y, 2019)
"Despite advances in cancer therapies, glioblastoma multiforme treatment remains inefficient due to the brain-blood barrier (BBB) inhibitory activity and to the low temozolomide (TMZ) chemotherapeutic selectivity."7.91Targeted and Synergic Glioblastoma Treatment: Multifunctional Nanoparticles Delivering Verteporfin as Adjuvant Therapy for Temozolomide Chemotherapy. ( de Melo, MT; Paula, LB; Pellosi, DS; Tedesco, AC, 2019)
"Standard-of-care treatment of glioblastomas involves maximal safe resection and adjuvant temozolomide chemo-radiotherapy."7.91Determining a cut-off residual tumor volume threshold for patients with newly diagnosed glioblastoma treated with temozolomide chemoradiotherapy: A multicenter cohort study. ( Chan, DTM; Chan, KY; Ho, JMK; Lam, SW; Lee, MWY; Mak, CHK; Poon, WS; Tse, TPK; Wong, ST; Woo, PYM, 2019)
"The aims of the present study were to compare the longitudinal changes of glioblastoma multiforme after radiotherapy (RT) between 11C-methionine positron emission tomography (MET-PET) and gadolinium (Gd)-enhanced magnetic resonance imaging (MRI) and to clarify whether these changes were predictive of survival."7.91Dissociation Between 11C-Methionine-Positron Emission Tomography and Gadolinium-Enhanced Magnetic Resonance Imaging in Longitudinal Features of Glioblastoma After Postoperative Radiotherapy. ( Asano, Y; Ikegame, Y; Iwama, T; Kawasaki, T; Miwa, K; Shinoda, J; Takei, H; Yano, H; Yokoyama, K, 2019)
"When only treated with D,L-methadone, 1 µM of the opioid was sufficient to reduce viability of fibroblasts, whereas 10 µM was needed to significantly reduce glioblastoma cell viability."7.91D,L-Methadone does not improve radio- and chemotherapy in glioblastoma in vitro. ( Baran-Schmidt, R; Dietterle, J; Gaunitz, F; Glasow, A; Matusova, M; Meixensberger, J; Neumann, K; Oppermann, H, 2019)
"Although temozolomide (TMZ) resistance is a significant clinical problem in glioblastoma (GBM), its underlying molecular mechanisms are poorly understood."7.91Exosomal transfer of miR-1238 contributes to temozolomide-resistance in glioblastoma. ( Shi, Z; Yan, W; Yin, J; You, Y; Zeng, A; Zhang, Z, 2019)
"Temozolomide (TMZ) is an alkylating agent used in the treatment of high-grade malignant glioma, notably glioblastoma multiforme, the most aggressive form of brain cancer."7.91Are There Thresholds in Glioblastoma Cell Death Responses Triggered by Temozolomide? ( He, Y; Kaina, B, 2019)
" In this preliminary study, the purpose was to evaluate the feasibility of APT imaging in monitoring the early therapeutic response to nitroxoline (NTX) in a temozolomide (TMZ)-resistant glioblastoma multiforme (GBM) mouse model, which was compared with diffusion-weighted imaging (DWI)."7.91Assessment of Early Therapeutic Response to Nitroxoline in Temozolomide-Resistant Glioblastoma by Amide Proton Transfer Imaging: A Preliminary Comparative Study with Diffusion-weighted Imaging. ( Cho, HR; Choi, SH; Kumari, N; Thakur, N, 2019)
"The acquired drug resistance has been regarded as a main barrier for the effective treatment of temozolomide (TMZ) in glioblastoma (GBM)."7.91miR-126-3p sensitizes glioblastoma cells to temozolomide by inactivating Wnt/β-catenin signaling via targeting SOX2. ( Li, X; Liu, X; Luo, W; Song, Z; Yan, D; Zhao, S; Zhu, X, 2019)
"The aim of this current work was to study the therapeutic enhancement of temozolomide (TMZ) on gliomavia combining with calycosin and FMN."7.91In vitro and in vivo Study on Glioma Treatment Enhancement by Combining Temozolomide with Calycosin and Formononetin. ( Fan, H; Fan, Y; Li, Y; Ni, Q; Zhang, X, 2019)
"To identify novel epigenetic signatures that could provide predictive information that is complementary to promoter methylation status of the O-6-methylguanine-DNA methyltransferase (MGMT) gene for predicting temozolomide (TMZ) response, among glioblastomas (GBMs) without glioma-CpGs island methylator phenotype (G-CIMP) METHODS: Different cohorts of primary non-G-CIMP GBMs with genome-wide DNA methylation microarray data were included for discovery and validation of a multimarker signature, combined using a RISK score model."7.91Novel predictive epigenetic signature for temozolomide in non-G-CIMP glioblastomas. ( Aubry, M; Barnholtz-Sloan, J; Etcheverry, A; He, YL; Liu, BL; Liu, YH; Lu, ZF; Mosser, J; Yin, AA; Zhang, X, 2019)
"Despite the increased understanding of the oncological mechanisms underlying Glioblastoma multiforme (GBM) pathophysiology, and recent advances in therapeutic strategies such as maximal surgical resection and post-operative radiotherapy with concomitant and adjuvant temozolomide chemotherapy, the prognosis for patients with brain tumors remains limited."7.91microRNA-181d associated with the methylation status of the MGMT gene in Glioblastoma multiforme cancer stem cells submitted to treatments with ionizing radiation and temozolomide. ( Carlotti, CG; de Assis Cirino, ML; Lizarte Neto, FS; Matias, CCMS; Pereira-da-Silva, G; Peria, FM; Rodrigues, AR; Tirapelli, DPDC; Trevisan, FA, 2019)
"We formulated an ultra-small, gadolinium-based nanoparticle (AGuIX) with theranostic properties to simultaneously enhance MRI tumor delineation and radiosensitization in a glioma model."7.91Ultrasmall theranostic gadolinium-based nanoparticles improve high-grade rat glioma survival. ( Appelboom, G; Barbier, EL; Bräuer-Krisch, E; Chang, SD; Dufort, S; Le Duc, G; Lux, F; Roux, S; Sancey, L; Tillement, O; Verry, C; Zhang, M, 2019)
"The acquisition of temozolomide resistance is a major clinical challenge for glioblastoma treatment."7.91Acquired temozolomide resistance in MGMT-deficient glioblastoma cells is associated with regulation of DNA repair by DHC2. ( Chen, Z; Deng, S; Guo, M; Huang, G; Lei, B; Li, Y; Li, Z; Liu, Y; Pan, J; Qi, S; Wang, H; Xiang, W; Yi, GZ; Yu, L; Zhang, X, 2019)
"This study aimed to screen in vitro antitumour activity of the redox couple avarol/avarone against the human malignant glioma cell line U-251 MG for the first time."7.88The redox couple avarol/avarone in the fight with malignant gliomas: the case study of U-251 MG cells. ( Glumac, M; Jakimov, D; Kojic, V; Pejin, B; Tommonaro, G, 2018)
"Glioblastoma (GBM) is an aggressive brain tumor with temozolomide (TMZ)-based chemotherapy as the main therapeutic strategy."7.88Low Dose of Doxorubicin Potentiates the Effect of Temozolomide in Glioblastoma Cells. ( Kipper, FC; Lenz, G; Lopez, PLDC; Silva, AO; Villodre, ES, 2018)
"We evaluated stereotactic volume modulated arc radiotherapy (VMAT) for canine gliomas, alone (radiotherapy [RT]) and in combination with temozolomide (RT + TMZ), compared with palliation."7.88Frameless stereotactic radiotherapy alone and combined with temozolomide for presumed canine gliomas. ( Bianchi, C; Carrara, N; Dolera, M; Finesso, S; Malfassi, L; Marcarini, S; Mazza, G; Pavesi, S; Sala, M; Urso, G, 2018)
"Standard treatment for patients with primary glioblastoma (GBM) includes surgery, radiotherapy, and concomitant and adjuvant temozolomide (TMZ)."7.88Prognostic importance of temozolomide-induced neutropenia in glioblastoma, IDH-wildtype patients. ( Hama, S; Kawamata, T; Kurisu, K; Muragaki, Y; Nosaka, R; Saito, T; Sugiyama, K; Takayasu, T; Yamasaki, F, 2018)
"Our study tested the diagnostic accuracy of increased signal intensity (SI) within FLAIR MR images of resection cavities in differentiating early progressive disease (ePD) from pseudoprogression (PsP) in patients with glioblastoma treated with radiotherapy with concomitant temozolomide therapy."7.88Increased signal intensity within glioblastoma resection cavities on fluid-attenuated inversion recovery imaging to detect early progressive disease in patients receiving radiotherapy with concomitant temozolomide therapy. ( Agrawal, JP; Erickson, BJ; Korfiatis, P; Perry, LA, 2018)
" By manipulation of Cx43 expression or gap junction function, we found that there were gap junction-dependent and independent effect of Cx43 on temozolomide (TMZ) sensitivity in U87 glioblastoma cells."7.88Tramadol attenuates the sensitivity of glioblastoma to temozolomide through the suppression of Cx43‑mediated gap junction intercellular communication. ( Huang, H; Ma, L; Peng, J; Peng, Y; Shao, M; Wang, L; Xia, Z; Zhong, G; Zhu, Z, 2018)
"Numerous studies suggested autophagy was involved in temozolomide (TMZ) resistance in glioma."7.88Upregulation of CASC2 sensitized glioma to temozolomide cytotoxicity through autophagy inhibition by sponging miR-193a-5p and regulating mTOR expression. ( Du, J; Fang, X; Huang, X; Jiang, C; Li, X; Liu, Z; Shen, F; Su, J; Wang, X, 2018)
"Although upfront temozolomide (TMZ) has been widely-used to treat 1p/19q-codeleted diffuse low-grade gliomas (LGG), its long-term impact on the growth kinetics of these tumors has not been determined."7.88Long-term impact of temozolomide on 1p/19q-codeleted low-grade glioma growth kinetics. ( Alentorn, A; Barritault, M; Bruna, J; Delattre, JY; Ducray, F; Honnorat, J; Idbaih, A; Izquierdo, C; Kaloshi, G; Meyronet, D; Ricard, D; Simó, M, 2018)
"The purpose of the study is to investigate the efficacy of combined treatment with temozolomide (TMZ) and metformin for glioblastoma (GBM) in vitro and in vivo."7.88High-Dose Metformin Plus Temozolomide Shows Increased Anti-tumor Effects in Glioblastoma In Vitro and In Vivo Compared with Monotherapy. ( Hong, YK; Lee, JE; Lim, JH; Yang, SH, 2018)
"The impact of DNA mismatch repair (MMR) on resistance to temozolomide (TMZ) therapy in patients with glioblastoma (GBM) is recently reported but the mechanisms are not understood."7.88Up-regulation of MSH6 is associated with temozolomide resistance in human glioblastoma. ( Dong, T; Dong, Y; Gao, Y; Gong, Y; Li, Q; Pei, C; Ren, H; Su, J; Sun, Q; Xiao, Y; Xing, W; Zhen, Z; Zhou, P, 2018)
"Resistance to temozolomide (TMZ) is a major clinical challenge in glioma treatment, but the mechanisms of TMZ resistance are poorly understood."7.88Fasudil increases temozolomide sensitivity and suppresses temozolomide-resistant glioma growth via inhibiting ROCK2/ABCG2. ( Ding, Y; Hu, R; Liu, X; Wang, Q; Yang, M; Zhang, X; Zhou, W, 2018)
"To retrospectively determine the safety and efficacy of combined chemotherapy with carmustine (BCNU) wafer, bevacizumab, and temozolomide plus radiotherapy in patients with newly diagnosed glioblastoma (GBM)."7.88Advantages and Disadvantages of Combined Chemotherapy with Carmustine Wafer and Bevacizumab in Patients with Newly Diagnosed Glioblastoma: A Single-Institutional Experience. ( Akiyama, Y; Enatsu, R; Kimura, Y; Mikami, T; Mikuni, N; Wanibuchi, M, 2018)
"A standard post-concomitant radiochemotherapy involving adjuvant temozolomide (TMZ) was stopped after 6 cycles for high-grade gliomas (HGG)."7.88Tumor Volume Changes During and After Temozolomide Treatment for Newly Diagnosed Higher-Grade Glioma (III and IV). ( Ho, JT; Ho, RW; Lin, WC; Lin, YJ; Lin, YT; Lu, CH; Tsai, NW; Wang, HC, 2018)
" This phenomenon, which has deleterious outcomes for the patient, has long been observed in patients with glioblastoma receiving temozolomide (TMZ)-based radiochemotherapy."7.88Characterizing the molecular mechanisms of acquired temozolomide resistance in the U251 glioblastoma cell line by protein microarray. ( Cui, Y; Feng, H; He, H; Li, J; Li, S; Lin, J; Qiu, G; Song, C; Wei, W; Wu, X; Xu, Q; Zuo, J, 2018)
"Multi-institutional data from 159 patients with newly diagnosed glioblastoma who received adjuvant temozolomide concomitant chemoradiotherapy (CCRT) were collected."7.88A Comparative Analysis of the Usefulness of Survival Prediction Models for Patients with Glioblastoma in the Temozolomide Era: The Importance of Methylguanine Methyltransferase Promoter Methylation, Extent of Resection, and Subventricular Zone Location. ( Chan, D; Chan, KY; Ho, J; Lam, S; Lee, M; Ma, E; Mak, C; Poon, WS; Wong, ST; Wong, WK; Woo, P, 2018)
"To evaluate the prognostic value of the Glasgow Prognostic Score (GPS), the combination of C-reactive protein (CRP) and albumin, in glioblastoma multiforme (GBM) patients treated with radiotherapy (RT) and concurrent plus adjuvant temozolomide (GPS)."7.88Prognostic value of the Glasgow Prognostic Score for glioblastoma multiforme patients treated with radiotherapy and temozolomide. ( Ciner, F; Guler, OC; Mertsoylu, H; Ozdemir, Y; Selek, U; Topkan, E; Tufan, K; Yildirim, BA, 2018)
"To identify patients with recurrent glioblastoma after temozolomide (TMZ) concurrent with and adjuvant to radiotherapy who could benefit from TMZ rechallenge at the time of disease progression."7.88Temozolomide rechallenge in recurrent glioblastoma: when is it useful? ( Bartolini, S; Brandes, AA; Cubeddu, A; De Biase, D; Di Battista, M; Franceschi, E; Lamberti, G; Minichillo, S; Mura, A; Paccapelo, A; Pession, A; Tallini, G; Tosoni, A; Visani, M, 2018)
"Temozolomide (TMZ) is the most frequent adjuvant chemotherapy drug in gliomas."7.88Temozolomide combined with PD-1 Antibody therapy for mouse orthotopic glioma model. ( Dai, B; Li, J; Qi, N; Zhang, G, 2018)
"To investigate the clinical efficacy of stereotactic radiation therapy combined with temozolomide on recurrent glioma."7.88[Clinical efficacy of stereotactic radiation therapy combined with temozolomide on recurrent brain glioma]. ( Jiang, C; Li, X; Liu, S; Tang, S; Zhao, H, 2018)
"Human glioblastoma U251 and T98 cells and normal astrocytes C8D1A were loaded with coenzyme Q10 (CoQ)."7.88Regulation of the oxidative balance with coenzyme Q10 sensitizes human glioblastoma cells to radiation and temozolomide. ( Alcaín, FJ; Ariza, J; Arjona-Gutiérrez, J; De la Mata, M; Durán-Prado, M; Ferrín, G; Frontiñán-Rubio, J; Gil-Agudo, A; Gómez, MV; Lozano, E; Martínez-González, A; Moreno, M; Nieva-Velasco, CM; Peinado, JR; Pérez-García, VM; Pérez-Romasanta, L; Pesic, M; Santiago-Mora, RM; Villalba, JM, 2018)
"We retrospectively analyzed the safety and efficacy of hypofractionated radiotherapy (45 Gy/15 fr) combined with temozolomide (TMZ) followed by bevacizumab (BEV) salvage treatment in 18 glioblastoma patients aged > 75 years."7.88Treatment outcomes of hypofractionated radiotherapy combined with temozolomide followed by bevacizumab salvage therapy in glioblastoma patients aged > 75 years. ( Kayama, T; Matsuda, KI; Nemoto, K; Sakurada, K; Sonoda, Y, 2018)
"Temozolomide (TMZ) is currently the first-line drug used for clinical postoperative or non-surgical chemotherapy for glioma, but acquired and intrinsic resistance to TMZ limits its application."7.88Synergistic Anticancer Effects of Formononetin and Temozolomide on Glioma C6 Cells. ( Fan, H; Li, Y; Ni, Q; Wang, Y; Zhang, X, 2018)
"Temozolomide (TMZ) is the preferred chemotherapeutic drug approved for the Glioblastoma multiforme (GBM) treatment."7.88miR-1268a regulates ABCC1 expression to mediate temozolomide resistance in glioblastoma. ( Deng, S; Guo, M; Li, Y; Liu, Y; Peng, Y; Qi, S; Ren, J; Shu, S; Yi, G; Zhao, L, 2018)
"Recently, D,L-methadone has been put forward as adjuvant treatment in glioblastoma (GBM)."7.88Efficacy of D,L-methadone in the treatment of glioblastoma in vitro. ( Brawanski, A; Brawanski, K; Brockhoff, G; Freyschlag, C; Hau, P; Lohmeier, A; Proescholdt, MA; Riemenschneider, MJ; Thomé, C; Vollmann-Zwerenz, A, 2018)
"Temozolomide (TMZ) is the current first-line chemotherapy for treatment of glioblastoma multiforme (GBM)."7.88Brain Targeting by Liposome-Biomolecular Corona Boosts Anticancer Efficacy of Temozolomide in Glioblastoma Cells. ( Arcella, A; Capriotti, AL; Caracciolo, G; Digiacomo, L; Frati, L; Mahmoudi, M; Oliva, MA; Palchetti, S; Pozzi, D; Rota, R; Screpanti, I; Tsaouli, G, 2018)
" Multidrug resistance, particularly resistance to temozolomide (TMZ), is a challenge in combating glioma, and more effective therapies are needed."7.88Newcastle disease virus enhances the growth-inhibiting and proapoptotic effects of temozolomide on glioblastoma cells in vitro and in vivo. ( Bai, Y; Chen, Y; Dong, X; Hong, X; Li, S; Li, Y; Liu, X; Su, X; Zhao, G, 2018)
" For example, temozolomide (TMZ), of use for glioblastoma (GBM) treatment, appears as capable of inducing autophagy partially inhibiting cancer cell proliferation."7.88Inhibition of autophagy increases susceptibility of glioblastoma stem cells to temozolomide by igniting ferroptosis. ( Ascione, B; Buccarelli, M; D'Alessandris, QG; De Pascalis, I; Larocca, LM; Malorni, W; Marconi, M; Martini, M; Matarrese, P; Pacioni, S; Pallini, R; Ricci-Vitiani, L, 2018)
"Chemoresistance blunts the effect of Temozolomide (TMZ) in the treatment of glioblastoma multiforme (GBM)."7.88Exosomal transfer of miR-151a enhances chemosensitivity to temozolomide in drug-resistant glioblastoma. ( Huang, X; Li, R; Shen, F; Wang, X; Wei, Z; Wu, W; Yan, W; Yin, J; You, Y; Zeng, A; Zhou, X, 2018)
"In this study, we aimed to evaluate the expression and functions of MAPK8 in temozolomide (TMZ) -resistant glioblastoma cells as well as to explore the mechanism of TMZ resistance in glioblastoma cells."7.88MAPK8 mediates resistance to temozolomide and apoptosis of glioblastoma cells through MAPK signaling pathway. ( Hou, S; Sha, LG; Xu, P; Zhang, G, 2018)
"To estimate the mean lifetime survival benefit, an essential component of health economic evaluations in oncology, of adding tumor treating fields (TTFields) to maintenance temozolomide (TMZ) for newly diagnosed glioblastoma patients."7.88Estimated lifetime survival benefit of tumor treating fields and temozolomide for newly diagnosed glioblastoma patients. ( Guzauskas, GF; Salzberg, M; Wang, BC, 2018)
"Discriminating between tumor recurrence and treatment effects in glioblastoma patients undergoing radiation-temozolomide (RT/TMZ) therapy remains a major clinical challenge."7.88Diagnostic utility of restriction spectrum imaging (RSI) in glioblastoma patients after concurrent radiation-temozolomide treatment: A pilot study. ( Bartsch, H; Chen, CC; Dale, AM; Farid, N; Khan, UA; Rennert, RC; White, NS, 2018)
"Radiotherapy with procarbazine, lomustine, and vincristine (PCV) improves overall survival in patients with anaplastic oligodendroglioma 1p19q codeleted."7.88Radiotherapy plus temozolomide or PCV in patients with anaplastic oligodendroglioma 1p19q codeleted. ( Castro-Martinez, E; Gonzalez-Aguilar, A; Guerrero-Juarez, V; Gutierrez-Aceves, A; Hernandez-Hernandez, A; Lopez-Martinez, M; Peiro-Osuna, RP; Reyes-Moreno, I; Santos-Zambrano, J, 2018)
"A series of polymer-drug conjugates based on 2-methacryloyloxyethyl phosphorylcholine (MPC) was prepared with the glioblastoma drug temozolomide (TMZ) as pendent groups."7.88Polymer-Temozolomide Conjugates as Therapeutics for Treating Glioblastoma. ( Emrick, T; Saha, B; Skinner, M; Ward, SM, 2018)
"The efficacy of temozolomide (TMZ) chemotherapy for treating newly diagnosed glioblastoma (GBM), a primary brain tumor with short survival, was demonstrated in a clinical trial in 2005, and since then, the standard-of-care for newly diagnosed GBM has been maximal safe surgery followed by 60 Gray of radiation with concomitant and adjuvant TMZ (standard radiotherapy and TMZ)."7.88Glioblastoma Treatment with Temozolomide and Bevacizumab and Overall Survival in a Rural Tertiary Healthcare Practice. ( Carter, TC; Lawler, BE; Medina-Flores, R, 2018)
"Radiation with concurrent and adjuvant (6 cycles) temozolomide (TMZ) is the established standard of postsurgical care for newly diagnosed glioblastoma (GBM)."7.85Is more better? The impact of extended adjuvant temozolomide in newly diagnosed glioblastoma: a secondary analysis of EORTC and NRG Oncology/RTOG. ( Baumert, BG; Blumenthal, DT; Brown, PD; Burt Nabors, L; Corn, BW; Erridge, SC; Gilbert, MR; Golfinopoulos, V; Gorlia, T; Hegi, ME; Hyun Nam, D; Kim, MM; Mason, WP; Mehta, MP; Mirimanoff, RO; Perry, JR; Reardon, DA; Stupp, R; van den Bent, MJ; Weller, M; Zhang, P, 2017)
"To determine if there is an association between the incidental radiation dose to the subventricular zone and survival in patients with glioblastoma multiforme treated with surgery, radiotherapy and temozolomide."7.85Influence of incidental radiation dose in the subventricular zone on survival in patients with glioblastoma multiforme treated with surgery, radiotherapy, and temozolomide. ( Algara, M; Foro Arnalot, P; Granados, R; Membrive, I; Ortiz, A; Pera, O; Reig, A; Rodriguez, N; Sanz, X, 2017)
"To compare various pro-apoptotic effects of synthetic 4-thiazolidinone derivative (Les-3288), doxorubicin (Dox) and temozolomide (TMZ) in the treatment of human glioma U251 cells to improve treatment outcomes of glioblastoma and avoid anticancer drug resistance."7.85Differential pro-apoptotic effects of synthetic 4-thiazolidinone derivative Les-3288, doxorubicin and temozolomide in human glioma U251 cells. ( Finiuk, N; Grytsyna, II; Klyuchivska, OY; Lehka, L; Lesyk, RB; Panchuk, RR; Starykovych, MO; Stoika, RS; Zіmenkovsky, BS; Коbylinska, LI, 2017)
"In glioblastoma several histone demethylase genes (KDM) are overexpressed compared to normal brain tissue and the development of Temozolomide (TMZ) resistance is accompanied by the transient further increased expression of KDM5A and other KDMs following a mechanism that we defined as "epigenetic resilience"."7.85Small molecules targeting histone demethylase genes (KDMs) inhibit growth of temozolomide-resistant glioblastoma cells. ( Allemanni, G; Banelli, B; Daga, A; Forlani, A; Marubbi, D; Pistillo, MP; Profumo, A; Romani, M, 2017)
"Glioblastoma multiforme (GBM) exhibits high resistance to the standard treatment of temozolomide (TMZ) combined with radiotherapy, due to its remarkable cell heterogeneity."7.85Comparative analysis of the effects of a sphingosine kinase inhibitor to temozolomide and radiation treatment on glioblastoma cell lines. ( Abdollahi, A; Dokic, I; Klein, C; Oancea-Castillo, LR; Régnier-Vigouroux, A; Weber, KJ, 2017)
"Temozolomide (TMZ) is a promising chemotherapeutic agent to treat Glioblastoma multiforme (GBM)."7.85MiR-181b modulates chemosensitivity of glioblastoma multiforme cells to temozolomide by targeting the epidermal growth factor receptor. ( Chen, Y; Li, R; Liu, N; Pan, M; Shi, Z; Wang, X; Yan, W; You, Y; Zhang, J, 2017)
" For these reasons, the anti-glioblastoma drug temozolomide was tested in vitro for activity against bloodstream forms of T."7.85Front-line glioblastoma chemotherapeutic temozolomide is toxic to Trypanosoma brucei and potently enhances melarsoprol and eflornithine. ( Rushworth, SA; Steverding, D, 2017)
"Limited benefits and clinical utility of temozolomide (TMZ) for glioblastoma (GB) are frequently compromised by the development of acquired drug resistance."7.85Connective tissue growth factor promotes temozolomide resistance in glioblastoma through TGF-β1-dependent activation of Smad/ERK signaling. ( Fu, Z; Guo, H; Lian, C; Liu, B; Xu, N; Yang, Z; Zeng, H, 2017)
" In the present study, whether MALAT1 contributes to the resistance of glioblastoma cell lines to temozolomide (TMZ) was investigated."7.85Long Non-Coding RNA MALAT1 Decreases the Sensitivity of Resistant Glioblastoma Cell Lines to Temozolomide. ( Dong, Y; Guan, F; Li, D; Li, H; Liu, X; Wang, H; Yan, D; Yang, B; Yuan, X, 2017)
"The present study analyzed outcomes of surgery followed by concomitant chemoradiotherapy (CCRT) with temozolomide (TMZ) in patients with newly diagnosed glioblastoma (GBM) at a single institution."7.85Long-term outcomes of concomitant chemoradiotherapy with temozolomide for newly diagnosed glioblastoma patients: A single-center analysis. ( Ahn, SS; Chang, JH; Cho, J; Choi, HJ; Hong, CK; Kang, SG; Kim, DS; Kim, EH; Kim, SH; Lee, KS; Lee, SK; Moon, JH; Park, HH; Roh, TH; Suh, CO, 2017)
"Recent experimental data showed that the PI3K pathway contributes to resistance to temozolomide (TMZ) in paediatric glioblastoma and that this effect is reversed by combination treatment of TMZ with a PI3K inhibitor."7.85In vitro nuclear magnetic resonance spectroscopy metabolic biomarkers for the combination of temozolomide with PI3K inhibition in paediatric glioblastoma cells. ( Agliano, A; Al-Saffar, NMS; Balarajah, G; Clarke, PA; Jackson, LE; Jones, C; Leach, MO; Marshall, LV; Pearson, ADJ; Sidhu, J; Workman, P, 2017)
"Temozolomide is the first chemotherapeutic agent proven effective for patients with newly diagnosed glioblastoma."7.85Feasibility and safety of extended adjuvant temozolomide beyond six cycles for patients with glioblastoma. ( Chan, DT; Hsieh, SY; Kam, MK; Loong, HH; Ng, SC; Poon, DM; Poon, WS; Tsang, WK, 2017)
"Acquisition of temozolomide (TMZ) resistance is a major factor leading to the failure of glioblastoma (GBM) treatment."7.85Specificity protein 1-modulated superoxide dismutase 2 enhances temozolomide resistance in glioblastoma, which is independent of O ( Chang, KY; Chang, WC; Chen, KY; Chou, SW; Chuang, CK; Chuang, JY; Hsu, CC; Hsu, TI; Hung, JJ; Kao, TJ; Ko, CY; Liou, JP; Liu, JJ; Liu, MS; Tsai, SY, 2017)
"To assess the efficacy and cost-effectiveness of modulated electrohyperthermia (mEHT) concurrent to dose-dense temozolomide (ddTMZ) 21/28 days regimen versus ddTMZ 21/28 days alone in patients with recurrent glioblastoma (GBM)."7.85Clinical and economic evaluation of modulated electrohyperthermia concurrent to dose-dense temozolomide 21/28 days regimen in the treatment of recurrent glioblastoma: a retrospective analysis of a two-centre German cohort trial with systematic comparison ( Roussakow, SV, 2017)
" Standard of care for glioblastoma (GBM) includes temozolomide chemotherapy, which is not curative, due, in part, to residual therapy-resistant brain tumor-initiating cells (BTICs)."7.85Addition of carbonic anhydrase 9 inhibitor SLC-0111 to temozolomide treatment delays glioblastoma growth in vivo. ( Audia, A; Bar, EE; Benavides, GA; Bevensee, MO; Bhat, KP; Boyd, NH; Cooper, SJ; Darley-Usmar, V; Dedhar, S; Fried, J; Gillespie, GY; Gordon, E; Griguer, C; Hackney, JR; Hjelmeland, AB; Landis, CJ; McDonald, PC; Nabors, B; Nozell, S; Scott, SE; Spina, R; Tran, AN; Walker, K; Xu, B, 2017)
"It is controversial whether concurrent chemoradiotherapy (CRT) with temozolomide is feasible and beneficial in elderly patients with glioblastoma."7.85A Model to Predict the Feasibility of Concurrent Chemoradiotherapy With Temozolomide in Glioblastoma Multiforme Patients Over Age 65. ( Fietkau, R; Knippen, S; Lahmer, G; Putz, F; Semrau, S, 2017)
"The current standard treatment protocol for patients with newly diagnosed glioblastoma (GBM) includes surgery, radiotherapy, and concomitant and adjuvant temozolomide (TMZ)."7.85Permeability Surface Area Product Using Perfusion Computed Tomography Is a Valuable Prognostic Factor in Glioblastomas Treated with Radiotherapy Plus Concomitant and Adjuvant Temozolomide. ( Ikawa, F; Ishifuro, M; Kawamata, T; Kurisu, K; Muragaki, Y; Nishibuchi, I; Nosaka, R; Saito, T; Sugiyama, K; Takayasu, T; Yamasaki, F, 2017)
"It is unknown whether the addition of temozolomide (TMZ) to radiotherapy (RT) is associated with improved overall survival (OS) among older glioblastoma patients."7.85Comparative effectiveness of radiotherapy with vs. without temozolomide in older patients with glioblastoma. ( Arvold, ND; Cefalu, M; Dominici, F; Schrag, D; Wang, Y; Zigler, C, 2017)
" In this study, we investigated the effect of silver nanoparticles (AgNPs) on human glioma U251 cells and its role in the combinational use with Temozolomide (TMZ), an imidazotetrazine derivative of the alkylating agent dacarbazine, against glioma cells."7.85Silver nanoparticles enhance the sensitivity of temozolomide on human glioma cells. ( Chen, H; Gong, Z; Gui, Q; Guo, X; Liang, P; Meng, J; Shi, H; Xu, Y; Zhu, W, 2017)
"The occurrence of an inherent or acquired resistance to temozolomide (TMZ) is a major burden for patients suffering from glioma."7.85Up-regulation of miR-497 confers resistance to temozolomide in human glioma cells by targeting mTOR/Bcl-2. ( Cai, L; Su, Z; Tu, M; Yu, Z; Zeng, B; Zheng, W; Zhu, D, 2017)
"The present study aimed to investigate whether overexpression of integrin-linked kinase (ILK) affects drug resistance to temozolomide (TMZ) in glioma cells."7.85Overexpression of ILK promotes temozolomide resistance in glioma cells. ( Bao, L; Liang, F; Wang, B; Zhang, SM; Zhang, SQ; Zhao, YS, 2017)
"Temozolomide-(TMZ)-based chemoradiotherapy defines the current gold standard for the treatment of newly diagnosed glioblastoma."7.85Temozolomide during radiotherapy of glioblastoma multiforme : Daily administration improves survival. ( Ballhausen, H; Belka, C; Nachbichler, SB; Niyazi, M; Schupp, G, 2017)
"Glioblastoma multiforme (GBM), the most common malignant brain tumor, is currently treated with temozolomide (TMZ), but GBM often exhibits resistance to TMZ."7.85FoxO3a induces temozolomide resistance in glioblastoma cells via the regulation of β-catenin nuclear accumulation. ( Li, L; Pei, H; Wang, H; Xia, Q; Xu, K; Zhang, Z, 2017)
"The chemotherapeutic agent temozolomide (TMZ) is widely used in the treatment of glioblastoma multiforme (GBM)."7.85Rutin increases the cytotoxicity of temozolomide in glioblastoma via autophagy inhibition. ( Cheng, YS; Ho, ASW; Kiang, KMY; Lee, D; Leung, GKK; Li, N; Poon, MW; Pu, JKS; Sun, S; Zhang, P; Zhang, X, 2017)
"To explore an association with survival of modifying the current standard of care for patients with newly diagnosed glioblastoma of surgery followed by radiotherapy plus concurrent and 6 cycles of maintenance temozolomide chemotherapy (TMZ/RT → TMZ) by extending TMZ beyond 6 cycles."7.85Limited role for extended maintenance temozolomide for newly diagnosed glioblastoma. ( Bendszus, M; Felsberg, J; Gramatzki, D; Hentschel, B; Herrlinger, U; Kickingereder, P; Loeffler, M; Pietsch, T; Reifenberger, G; Sabel, M; Schackert, G; Schlegel, U; Tonn, JC; Weller, M; Westphal, M; Wick, W, 2017)
"Arginine-glycine-aspartic acid peptide (RGD)-modified nanostructured lipid carriers (NLCs) were used for the delivery of temozolomide (TMZ) into the GBM to provide a new paradigm in gliomatosis cerebri treatment."7.83Novel RGD containing, temozolomide-loading nanostructured lipid carriers for glioblastoma multiforme chemotherapy. ( Du, J; Mao, G; Song, S; Zhu, X, 2016)
"Few data are available on temozolomide (TMZ) in ependymomas."7.83Temozolomide as salvage treatment for recurrent intracranial ependymomas of the adult: a retrospective study. ( Bosa, C; Cassoni, P; Fiano, V; Franchino, F; Magistrello, M; Pellerino, A; Rudà, R; Soffietti, R; Trevisan, M, 2016)
"Temozolomide is a standard chemotherapy agent for malignant gliomas, but the efficacy is still not satisfactory."7.83Temozolomide reverses doxorubicin resistance by inhibiting P-glycoprotein in malignant glioma cells. ( Kanamori, M; Saito, R; Shibahara, I; Sonoda, Y; Sugiyama, S; Tominaga, T; Zhang, R, 2016)
"Resistance of glioblastoma (GBM) to the front-line chemotherapeutic agent temozolomide (TMZ) continues to challenge GBM treatment efforts."7.83Connexin 43 Inhibition Sensitizes Chemoresistant Glioblastoma Cells to Temozolomide. ( Gourdie, RG; Guo, S; Jourdan, J; Kanabur, P; Lamouille, S; Murphy, SF; Osimani, AM; Pridham, KJ; Rodgers, CM; Sharma, S; Sheng, Z; Simonds, GR; Varghese, RT, 2016)
"We aimed to analyze the value of seizure reduction and radiological response as prognostic markers of survival in patients with low-grade glioma (LGG) treated with temozolomide (TMZ) chemotherapy."7.83Seizure reduction is a prognostic marker in low-grade glioma patients treated with temozolomide. ( Dirven, L; Heimans, JJ; Koekkoek, JA; Postma, TJ; Reijneveld, JC; Taphoorn, MJ; Vos, MJ, 2016)
"The survival benefits of patients with glioblastoma (GBM) remain unsatisfactory due to the intrinsic or acquired resistance to temozolomide (TMZ)."7.83Sulforaphane reverses chemo-resistance to temozolomide in glioblastoma cells by NF-κB-dependent pathway downregulating MGMT expression. ( Han, J; Lan, F; Wu, Q; Yang, Y; Yu, H; Yue, X, 2016)
"Resistance to temozolomide (TMZ) greatly limits chemotherapeutic effectiveness in glioblastoma (GBM)."7.83Patient-derived glioblastoma cells show significant heterogeneity in treatment responses to the inhibitor-of-apoptosis-protein antagonist birinapant. ( Boyd, AW; Byrne, AT; Day, BW; Flanagan, L; Kögel, D; Murray, DW; O'Brien, DF; Prehn, JH; Rehm, M; Salvucci, M; Stringer, BW; Tivnan, A; Zakaria, Z, 2016)
"O6-methylguanine-DNA methyltransferase (MGMT) protein expression using immunohistochemical analysis was proposed as a prognostic marker for patients with newly diagnosed glioblastoma (GBM) treated with radiation therapy with concurrent and adjuvant Temozolomide (TMZ)."7.83Immunohistochemical analysis of O6-methylguanine-DNA methyltransferase (MGMT) protein expression as prognostic marker in glioblastoma patients treated with radiation therapy with concomitant and adjuvant Temozolomide. ( El-Shorbagy, SH; Khedr, RA; Younis, SG, 2016)
"A gene drug delivery system for glioma therapy based on transferrin (Tf)-modified polyamidoamine dendrimer (PAMAM) was prepared."7.83Plasmid pORF-hTRAIL targeting to glioma using transferrin-modified polyamidoamine dendrimer. ( Gao, S; Hao, B; Hong, B; Jiang, C; Li, J, 2016)
" Human glioma U87MG or LNZ308 cells overexpressing either wild-type (wt) EGFR or EGFRvIII were treated with nimotuzumab, temozolomide, or both."7.83Nimotuzumab enhances temozolomide-induced growth suppression of glioma cells expressing mutant EGFR in vivo. ( Nagane, M; Nitta, Y; Shimizu, S; Shiokawa, Y; Shishido-Hara, Y; Suzuki, K, 2016)
"To confirm the hypothesis suggested above, a combined analysis of survival association of antiepileptic drug use at the start of chemoradiotherapy with temozolomide was performed in the pooled patient cohort (n = 1,869) of four contemporary randomized clinical trials in newly diagnosed glioblastoma: AVAGlio (Avastin in Glioblastoma; NCT00943826), CENTRIC (Cilengitide, Temozolomide, and Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma and Methylated Gene Promoter Status; NCT00689221), CORE (Cilengitide, Temozolomide, and Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma and Unmethylated Gene Promoter Status; NCT00813943), and Radiation Therapy Oncology Group 0825 (NCT00884741)."7.83Does Valproic Acid or Levetiracetam Improve Survival in Glioblastoma? A Pooled Analysis of Prospective Clinical Trials in Newly Diagnosed Glioblastoma. ( Chinot, O; Cloughesy, T; Gilbert, MR; Gorlia, T; Happold, C; Hegi, M; Mehta, MP; Nabors, LB; Perry, JR; Pugh, SL; Reardon, DA; Roth, P; Stupp, R; Weller, M; Wick, W, 2016)
" Triple-mutant astrocytes formed serially transplantable glioblastoma allografts that were sensitive to radiation but expressed MGMT and were resistant to temozolomide."7.83Core pathway mutations induce de-differentiation of murine astrocytes into glioblastoma stem cells that are sensitive to radiation but resistant to temozolomide. ( Bash, RE; Ewend, MG; Huey, L; McNeill, RS; Miller, CR; Schmid, RS; Simon, JM; Vitucci, M; Werneke, AM; White, KK; Wu, J, 2016)
"The current standard of care for glioblastoma (GBM) is surgical resection, radiotherapy, and treatment with temozolomide (TMZ)."7.83MR Studies of Glioblastoma Models Treated with Dual PI3K/mTOR Inhibitor and Temozolomide:Metabolic Changes Are Associated with Enhanced Survival. ( Chaumeil, MM; Eriksson, P; Phillips, JJ; Radoul, M; Ronen, SM; Wang, AS, 2016)
"The role of temozolomide concurrent with and adjuvant to radiotherapy (RT/TMZ) in elderly patients with glioblastoma (GBM) remains unclear."7.83Which elderly newly diagnosed glioblastoma patients can benefit from radiotherapy and temozolomide? A PERNO prospective study. ( Baruzzi, A; Bertolini, F; Biasini, C; Brandes, AA; Cavallo, MA; Crisi, G; Dazzi, C; Depenni, R; Ermani, M; Faedi, M; Franceschi, E; Michiara, M; Mucciarini, C; Paccapelo, A; Pasini, G; Pavesi, G; Pisanello, A; Servadei, F; Sturiale, C; Urbini, B, 2016)
"The combination of radiotherapy, temozolomide and valproic acid (VPA) has shown some promise in retrospective analyses of patients with glioblastoma, although their mechanisms of action remain unknown."7.83Adaptive Immune Response to and Survival Effect of Temozolomide- and Valproic Acid-induced Autophagy in Glioblastoma. ( Bumes, E; Eyüpoglu, IY; Hau, P; Hutterer, M; Proske, J; Savaskan, NE; Seliger, C; Uhl, M; Vollmann-Zwerenz, A; Walter, L, 2016)
"Clinical guidelines for gliosarcoma (GSM) are poorly defined and GSM patients are usually treated in accordance with existing guidelines for glioblastoma (GBM), with maximal surgical resection followed by chemoradiation with temozolomide (TMZ)."7.83Radiotherapy plus concomitant temozolomide in primary gliosarcoma. ( Adeberg, S; Bernhardt, D; Debus, J; Diehl, C; Harrabi, SB; Koelsche, C; Rieken, S; Unterberg, A; von Deimling, A, 2016)
" Food and Drug Administration and EMA-approved xCT inhibitor, sulfasalazine (SAS) in gliomas."7.83Sulfasalazine impacts on ferroptotic cell death and alleviates the tumor microenvironment and glioma-induced brain edema. ( Buchfelder, M; Dörfler, A; Engelhorn, T; Eyüpoglu, IY; Fan, Z; Ghoochani, A; Klucken, J; Minakaki, G; Rauh, M; Savaskan, N; Sehm, T, 2016)
"The effects of KLF8 on glioma cell proliferation, apoptosis and chemosensitivity to temozolomide (TMZ) were analyzed by Cell Counting Kit 8 assay and flow cytometry assay."7.83KLF8 Promotes Temozolomide Resistance in Glioma Cells via β-Catenin Activation. ( Wang, E; Wu, F; Yu, G, 2016)
"HIF-1α downregulation sensitizes U251 glioma cells to the temozolomide treatment via inhibiting MGMT expression and Notch1 pathway activation."7.83Downregulation of HIF-1a sensitizes U251 glioma cells to the temozolomide (TMZ) treatment. ( Huang, GH; Li, N; Lv, SQ; Ma, ZX; Sidlauskas, K; Tang, JH; Xiang, Y; Xu, QF; Zhang, EE, 2016)
"Although temozolomide (TMZ) is the most effective chemotherapy agent for glioma, chemotherapy resistance has limited its clinical use."7.83Fluoxetine synergizes with temozolomide to induce the CHOP-dependent endoplasmic reticulum stress-related apoptosis pathway in glioma cells. ( Chen, MH; Chen, W; Ma, J; Sun, LL; Wang, DC; Wang, FZ; Wang, H; Wang, XD; Yang, YR, 2016)
" In the case of glioma, temozolomide (TMZ) is the main option for treatment, but it has limited success due to drug resistance."7.83NRF2 and glutathione are key resistance mediators to temozolomide in glioma and melanoma cells. ( Fortunato, RS; Kajitani, GS; Menck, CF; Quinet, A; Rocha, CR, 2016)
"Temozolomide (TMZ) is the most commonly used alkylating agent in glioma chemotherapy."7.83miR-29c contribute to glioma cells temozolomide sensitivity by targeting O6-methylguanine-DNA methyltransferases indirectely. ( Liao, Y; Liu, J; Liu, Q; Lv, R; Qiu, X; Wu, M; Xiao, S; Yang, Z, 2016)
"Genotoxic chemotherapy with temozolomide (TMZ) is a mainstay of treatment for glioblastoma (GBM); however, at best, TMZ provides only modest survival benefit to a subset of patients."7.83Predicting the cell death responsiveness and sensitization of glioma cells to TRAIL and temozolomide. ( Johnston, G; Lincoln, FA; Murphy, BM; Noonan, J; Rehm, M; Weyhenmeyer, BC; Würstle, ML, 2016)
" 1) VPA treatment clearly sensitized glioma cells to temozolomide: A protruding VPA-induced molecular feature in this context was the transcriptional upregulation/reexpression of numerous solute carrier (SLC) transporters that was also reflected by euchromatinization on the histone level and a reexpression of SLC transporters in human biopsy samples after VPA treatment."7.83Molecular dissection of the valproic acid effects on glioma cells. ( Hau, P; Herold-Mende, C; Hoja, S; Proescholdt, M; Rehli, M; Riemenschneider, MJ; Schulze, M, 2016)
"Temozolomide (TMZ) is an alkylating agent that has become the mainstay treatment of the most malignant brain cancer, glioblastoma multiforme (GBM)."7.83Zinc enhances temozolomide cytotoxicity in glioblastoma multiforme model systems. ( Assoulin, M; Constantini, S; Daniels, D; Fisher, T; Freedman, S; Guez, D; Last, D; Mardor, Y; Mehrian-Shai, R; Moshe, I; Pismenyuk, T; Reichardt, JK; Simon, AJ; Toren, A; Yalon, M, 2016)
" The purpose of this study was determining the effects of HL156A, a newly designed biguanide with improved pharmacokinetics, on glioblastoma TSs (GMB TSs) and assess the feasibility of this drug as a new line of therapy against glioblastoma, alone or combined with a conventional therapeutic agent, temozolomide(TMZ)."7.83Inhibiting stemness and invasive properties of glioblastoma tumorsphere by combined treatment with temozolomide and a newly designed biguanide (HL156A). ( Chang, JH; Cheong, JH; Choi, J; Huh, YM; Jeon, JY; Kang, SG; Kim, EH; Kim, P; Kim, SH; Koh, I; Lee, JH; Lee, SJ; Park, J; Pollak, M; Shim, JK; Yook, JI; Yun, M, 2016)
" In the OP group with GBM and anaplastic glioma, patients treated with RT combined with temozolomide (TMZ) manifested significantly longer OS and PFS compared with patients assigned to RT alone (P < 0."7.83Radiation combined with temozolomide contraindicated for young adults diagnosed with anaplastic glioma. ( Cai, J; Jiang, T; Li, S; Li, W; Peng, X; Qiu, X; Wang, Y; Wu, C; Yang, P; Yao, K; You, G; Zhang, C; Zhang, W, 2016)
"Twenty patients with recurrent glioblastoma were treated with biweekly BEV plus temozolomide."7.83MRI and 11C-methyl-L-methionine PET Differentiate Bevacizumab True Responders After Initiating Therapy for Recurrent Glioblastoma. ( Beppu, T; Kato, K; Ogasawara, K; Sasaki, M; Sasaki, T; Sato, Y; Terasaki, K; Tomabechi, M, 2016)
"Concomitant use of temozolomide (TMZ) and radiotherapy, which is the standard therapy for patients with high-grade glioma, involves a unique regimen with multiple-day, long-term administration."7.83Combination of Palonosetron, Aprepitant, and Dexamethasone Effectively Controls Chemotherapy-induced Nausea and Vomiting in Patients Treated with Concomitant Temozolomide and Radiotherapy: Results of a Prospective Study. ( Akutsu, H; Ishikawa, E; Matsuda, M; Matsumura, A; Takano, S; Yamamoto, T, 2016)
"It has been reported that metformin acts synergistically with temozolomide (TMZ) to inhibit proliferation of glioma cells including glioblastoma multiforme (GBM)."7.83Metformin treatment reduces temozolomide resistance of glioblastoma cells. ( Kim, DH; Li, S; Liu, Y; Lu, G; Xue, H; Yang, SH; Zhu, JJ, 2016)
"Temozolomide (TMZ), an alkylating agent of the imidazotetrazine series, is a first-line chemotherapeutic drug used in the clinical therapy of glioblastoma multiforme, the most common and high-grade primary glioma in adults."7.83The Inhibition of microRNA-128 on IGF-1-Activating mTOR Signaling Involves in Temozolomide-Induced Glioma Cell Apoptotic Death. ( Chang, CK; Chen, KC; Chen, PH; Cheng, CH; Ho, KH; Lee, CC; Lin, CW; Liu, AJ; Shih, CM, 2016)
"The aim of this study was to investigate the effect of downregulating Hedgehog pathway by GANT61 on human glioma cells, examine the consequent changes of temozolomide (TMZ)-induced effects and explore the molecular mechanisms."7.83GANT61, a GLI inhibitor, sensitizes glioma cells to the temozolomide treatment. ( Cai, J; Chen, L; Jiang, C; Li, J; Li, R; Li, Y; Sun, Y; Yao, K; Zhai, X; Zhang, J; Zhao, S, 2016)
"Concurrent chemoradiotherapy with temozolomide, the current standard treatment after surgery for glioblastoma, could be shortened without increasing side effects for patients with poor prognostic features."7.81Hypofractionated chemoradiotherapy with temozolomide as a treatment option for glioblastoma patients with poor prognostic features. ( Choi, SH; Han, TJ; Kim, IH; Kim, TM; Lee, SH; Lim, YJ; Paek, SH; Park, CK; Park, SH, 2015)
"To explore the role of dynamic contrast material-enhanced magnetic resonance (MR) imaging in the differentiation of true progression from pseudoprogression in patients with glioblastoma on the basis of findings in entirely newly developed or enlarged enhancing lesions after concurrent radiation therapy and chemotherapy with temozolomide and to evaluate the diagnostic performance of the quantitative pharmacokinetic parameters obtained at dynamic contrast-enhanced MR imaging, such as the volume transfer constant (K(trans)), the extravascular extracellular space per unit volume of tissue(ve), and the blood plasma volume per unit volume of tissue(vp)."7.81Glioblastoma treated with concurrent radiation therapy and temozolomide chemotherapy: differentiation of true progression from pseudoprogression with quantitative dynamic contrast-enhanced MR imaging. ( Choi, SH; Kim, IH; Kim, JH; Kim, TM; Lee, SH; Park, CK; Park, SH; Sohn, CH; Yun, TJ, 2015)
"The cellular responses to two new temozolomide (TMZ) analogues, DP68 and DP86, acting against glioblastoma multiforme (GBM) cell lines and primary culture models are reported."7.81Evaluation of novel imidazotetrazine analogues designed to overcome temozolomide resistance and glioblastoma regrowth. ( Gynther, M; Mladek, AC; Phillips, RM; Ramirez, YP; Rautio, J; Ross, AH; Sakaria, JN; Wheelhouse, RT, 2015)
"The present in vitro study aimed to assess the effects of combining the mTOR inhibitor RAD001 and temozolomide (TMZ) together with irradiation by either low-linear energy transfer (LET) radiation (γ-rays) or high-LET radiation (fast neutrons) on the growth and cell survival of the human glioblastoma cell line U-87."7.81Combination of the mTOR inhibitor RAD001 with temozolomide and radiation effectively inhibits the growth of glioblastoma cells in culture. ( Bischoff, P; Burckel, H; Denis, JM; Gueulette, J; Josset, E; Noël, G; Slabbert, J, 2015)
"To evaluate 2 specific radiation schedules, each combined with temozolomide (TMZ), assessing their efficacy and safety in patients aged ≥65 years with newly diagnosed glioblastoma (GBM)."7.81Standard (60 Gy) or short-course (40 Gy) irradiation plus concomitant and adjuvant temozolomide for elderly patients with glioblastoma: a propensity-matched analysis. ( Arcella, A; Bozzao, A; Enrici, RM; Esposito, V; Giangaspero, F; Lanzetta, G; Minniti, G; Pace, A; Scaringi, C; Terrenato, I, 2015)
"Glioblastoma Multiforme (GBM), the most common and lethal adult primary tumor of the brain, showed a link between Sonic Hedgehog (SHH) pathway in the resistance to temozolomide (TMZ)."7.81Temozolomide resistance in glioblastoma occurs by miRNA-9-targeted PTCH1, independent of sonic hedgehog level. ( Greco, SJ; Ligon, KL; Munoz, JL; Rameshwar, P; Ramkissoon, SH; Rodriguez-Cruz, V, 2015)
" Chemotherapy has been observed to prolong overall survival rate and temozolomide (TMZ), a promising chemotherapeutic agent for treating glioblastoma (GBM), possesses the most effective clinical activity at present, although drug resistance limits its clinical outcome."7.81p53 upregulated modulator of apoptosis sensitizes drug-resistant U251 glioblastoma stem cells to temozolomide through enhanced apoptosis. ( Fan, Y; Guo, G; Li, Q; Lian, S; Liu, X; Miao, W; Wang, H; Wang, S; Wang, X; Yang, X, 2015)
"Temozolomide (TMZ) increases the overall survival of patients with glioblastoma (GBM), but its role in the clinical management of diffuse low-grade gliomas (LGG) is still being defined."7.81Evolution of DNA repair defects during malignant progression of low-grade gliomas after temozolomide treatment. ( Aburatani, H; Aihara, K; Berger, MS; Chang, SM; Costello, JF; Fouse, SD; Hallbeck, M; Heimans, JJ; Hong, C; Johnson, BE; Kloezeman, JJ; Lamfers, ML; Malmström, A; Mazor, T; Molinaro, AM; Mukasa, A; Reijneveld, JC; Saito, N; Söderkvist, P; Stenmark-Askmalm, M; Taylor, BS; van Thuijl, HF; Wesseling, P; Ylstra, B, 2015)
"Lack of robust predictive biomarkers, other than MGMT promoter methylation, makes temozolomide responsiveness in newly diagnosed glioblastoma (GBM) patients difficult to predict."7.81EGFR amplified and overexpressing glioblastomas and association with better response to adjuvant metronomic temozolomide. ( Bonetti, MF; Branca, C; Buglione, M; Buttolo, L; Cominelli, M; Dalerba, P; Facchetti, F; Finocchiaro, G; Furlan, D; Galli, R; Grisanti, S; Liserre, B; Liserre, R; Mazzoleni, S; Medicina, D; Pellegatta, S; Pellegrini, V; Pizzi, M; Poliani, PL, 2015)
" In this project, we evaluated the effects of silibinin, a natural plant component of milk thistle seeds, to potentiate toxic effects of chemotherapy drugs such as temozolomide, etoposide and irinotecan on LN229, U87 and A172 (P53 and phosphatase and tensin homolog (PTEN) -tumor suppressor-mutated) glioma cell lines."7.81The effect of silibinin in enhancing toxicity of temozolomide and etoposide in p53 and PTEN-mutated resistant glioma cell lines. ( Elhag, R; Mazzio, EA; Soliman, KF, 2015)
"In this study, we developed and characterized a delivery system for the epigenetic demethylating drug, decitabine, to sensitize temozolomide-resistant human glioblastoma multiforme (GBM) cells to alkylating chemotherapy."7.81Decitabine nanoconjugate sensitizes human glioblastoma cells to temozolomide. ( Cui, Y; Irudayaraj, J; Naz, A; Thompson, DH, 2015)
"Temozolomide (TMZ) is the first line drug in the care of high grade gliomas."7.81Temozolomide and radiotherapy versus radiotherapy alone in high grade gliomas: a very long term comparative study and literature review. ( Clemente, MA; Corsa, P; Cossa, S; Donno, E; Munafò, T; Parisi, F; Parisi, S; Perrone, A; Piombino, M; Raguso, A; Sanpaolo, G; Valle, G, 2015)
"Despite multimodal treatment, glioblastoma (GBM) therapy with temozolomide (TMZ) remains inefficient due to chemoresistance."7.81The metalloprotease-disintegrin ADAM8 contributes to temozolomide chemoresistance and enhanced invasiveness of human glioblastoma cells. ( Bartsch, JW; Biniossek, ML; Carl, B; Conrad, C; Culmsee, C; Dolga, AM; Dong, F; Eibach, M; Koller, G; Nimsky, C; Schieber, S; Schilling, O; Schlomann, U; Strik, H, 2015)
"High-grade gliomas, glioblastomas (GB), are refractory to conventional treatment combining surgery, chemotherapy, mainly temozolomide, and radiotherapy."7.81Metformin inhibits growth of human glioblastoma cells and enhances therapeutic response. ( Brem, H; Cohen-Jonathan Moyal, E; Dahan, P; Dang, VT; Lemarié, A; Saland, E; Sarry, JE; Scotland, SJ; Sesen, J; Skuli, N; Toulas, C; Tyler, BM, 2015)
"We examined whether the amino acid PET tracers, trans-1-amino-3-(18)F-fluorocyclobutanecarboxylic acid (anti-(18)F-FACBC) and (11)C-methyl-l-methionine ((11)C-Met), are suitable for detecting early responses to combination therapies including temozolomide (TMZ), interferon-β (IFN), and bevacizumab (Bev) in glioblastoma."7.81Amino acid PET tracers are reliable markers of treatment responses to single-agent or combination therapies including temozolomide, interferon-β, and/or bevacizumab for glioblastoma. ( Baden, A; Doi, Y; Kanagawa, M; Mizoi, K; Oka, S; Ono, M; Ono, T; Sasajima, T; Shimizu, H, 2015)
"Two independent temozolomide-treated glioblastoma cohorts-one Australian (Australian Genomics and Clinical Outcomes of Glioma, n = 163) and the other American (University of California Los Angeles/Kaiser Permanente Los Angeles, n = 159)-were studied."7.81The MGMT promoter SNP rs16906252 is a risk factor for MGMT methylation in glioblastoma and is predictive of response to temozolomide. ( Cloughesy, TF; Ha, W; Hitchins, MP; Lai, A; McDonald, KL; Nguyen, HN; Nowak, AK; Rapkins, RW; Wang, F, 2015)
"Resistance to temozolomide (TMZ) is a major obstacle in the treatment of glioblastoma multiforme (GBM)."7.81miR-20a mediates temozolomide-resistance in glioblastoma cells via negatively regulating LRIG1 expression. ( Mo, L; Qi, X; Wan, Y; Wang, Y; Wei, J; Xie, D; Xie, J; Yan, Q; Yang, S; Zhan, Q; Zhou, D, 2015)
" The objective of this study was to assess the survival benefit of LEV compared with other antiepileptic drugs as a chemosensitizer to temozolomide for patients with glioblastoma."7.81Survival benefit of levetiracetam in patients treated with concomitant chemoradiotherapy and adjuvant chemotherapy with temozolomide for glioblastoma multiforme. ( Han, JH; Joo, JD; Kim, CY; Kim, IA; Kim, T; Kim, YH; Kim, YJ; Yun, CH, 2015)
"It is currently unclear whether adjuvant therapy for WHO grade III anaplastic astrocytomas (AA) should be carried out as combined chemoradiotherapy with temozolomide (TMZ)--analogous to the approach for glioblastoma multiforme--or as radiotherapy (RT) alone."7.81Adjuvant temozolomide-based chemoradiotherapy versus radiotherapy alone in patients with WHO III astrocytoma: The Mainz experience. ( Giese, A; Mayer, A; Renovanz, M; Schmidberger, H; Schwanbeck, C; Sommer, C; Stockinger, M; Vaupel, P, 2015)
"Acute severe lymphopenia (ASL) frequently develops during radiation therapy (RT) and concurrent temozolomide (TMZ) for high-grade glioma (HGG) and is associated with decreased survival."7.81Clinical and Dosimetric Predictors of Acute Severe Lymphopenia During Radiation Therapy and Concurrent Temozolomide for High-Grade Glioma. ( Badiyan, SN; Campian, JL; Chicoine, MR; DeWees, TA; Dunn, G; Fergus, S; Huang, J; Kim, AH; Linette, G; Mullen, DF; Robinson, CG; Simpson, JR; Speirs, CK; Tran, DD, 2015)
"The AVAglio (Avastin in Glioblastoma) and RTOG-0825 randomized, placebo-controlled phase III trials in newly diagnosed glioblastoma reported prolonged progression-free survival (PFS), but not overall survival (OS), with the addition of bevacizumab to radiotherapy plus temozolomide."7.81Patients With Proneural Glioblastoma May Derive Overall Survival Benefit From the Addition of Bevacizumab to First-Line Radiotherapy and Temozolomide: Retrospective Analysis of the AVAglio Trial. ( Abrey, LE; Bais, C; Bourgon, R; Chinot, OL; Cloughesy, T; Garcia, J; Hegde, P; Henriksson, R; Kharbanda, S; Lai, A; Li, C; Mason, W; Moore, N; Nishikawa, R; Peale, F; Phillips, HS; Sandmann, T; Saran, F; Wick, W, 2015)
" The introduction of temozolomide (TMZ) has advanced chemotherapy for malignant gliomas."7.81NVP-BEZ235, a novel dual PI3K-mTOR inhibitor displays anti-glioma activity and reduces chemoresistance to temozolomide in human glioma cells. ( Chen, Y; Cheng, Y; Li, Y; Xie, G; Yao, G; Yu, Z; Zhang, G; Zhao, G; Zhou, G, 2015)
"Temozolomide plays a critical role in curing glioma at present."7.81Liposome encapsulated of temozolomide for the treatment of glioma tumor: preparation, characterization and evaluation. ( Gao, J; Huang, G; Liu, H; Wang, L; Wang, Z, 2015)
" Glioblastoma (GBM) has poor survival rate and uniformly acquired chemoresistance to its frontline agent, Temozolomide (TMZ)."7.81Temozolomide competes for P-glycoprotein and contributes to chemoresistance in glioblastoma cells. ( Munoz, JL; Rameshwar, P; Scotto, KW; Walker, ND, 2015)
" The present study was undertaken to determine whether the cytotoxicity of curcumin (diferuloylmethane), a natural polyphenolic compound isolated from turmeric (Curcuma longa Linn), in glioblastoma cells is mediated through upregulation of miR‑146a."7.81Induction of microRNA-146a is involved in curcumin-mediated enhancement of temozolomide cytotoxicity against human glioblastoma. ( Cai, T; Chen, YD; Liu, Q; Wang, ZF; Wu, H, 2015)
" Our aim was to determine whether the subependymal enhancement pattern and ADC can differentiate true progression from pseudoprogression in patients with glioblastoma multiforme treated with concurrent chemoradiotherapy by using temozolomide."7.81Independent Poor Prognostic Factors for True Progression after Radiation Therapy and Concomitant Temozolomide in Patients with Glioblastoma: Subependymal Enhancement and Low ADC Value. ( Choi, SH; Kim, IH; Kim, JH; Kim, TM; Lee, SH; Park, CK; Park, SH; Sohn, CH; Yoo, RE; Yun, TJ, 2015)
"Although temozolomide (TMZ) is the current first-line chemotherapy for glioblastoma multiforme (GBM), most patients either do not respond or ultimately fail TMZ treatment."7.81Encapsulation of temozolomide in a tumor-targeting nanocomplex enhances anti-cancer efficacy and reduces toxicity in a mouse model of glioblastoma. ( Chang, EH; DeMarco, J; Kim, E; Kim, SS; Pirollo, KF; Rait, A, 2015)
" Interestingly, our findings showed an association of metformin therapy and prolonged progression-free survival in glioblastoma patients with diabetes and therefore serve as a foundation for further preclinical and clinical investigations."7.81Metformin influences progression in diabetic glioblastoma patients. ( Adeberg, S; Ben Harrabi, S; Bernhardt, D; Bostel, T; Debus, J; Diehl, C; Koelsche, C; Mohr, A; Rieken, S, 2015)
"Mesoporous silica nanoparticles (MSNPs), 100 nm in size, incorporating a Cy5 fluorophore within the silica framework, are synthesized and loaded with the anti-cancer drug temozolomide (TMZ), used in the treatment of gliomas."7.81Combined Delivery of Temozolomide and Anti-miR221 PNA Using Mesoporous Silica Nanoparticles Induces Apoptosis in Resistant Glioma Cells. ( Bertucci, A; Brognara, E; Corradini, R; De Cola, L; Gambari, R; Manicardi, A; Prasetyanto, EA; Septiadi, D, 2015)
"The efficacy of temozolomide (TMZ) plus radiation therapy (RT) in elderly patients with glioblastoma is unclear."7.81Predictors of survival and effect of short (40 Gy) or standard-course (60 Gy) irradiation plus concomitant temozolomide in elderly patients with glioblastoma: a multicenter retrospective study of AINO (Italian Association of Neuro-Oncology). ( Anghileri, E; Bazzoli, E; Bellu, L; Berti, F; D'Avella, D; Dall'Agata, M; Della Puppa, A; Eoli, M; Fabi, A; Faedi, M; Ferrazza, P; Gurrieri, L; Lombardi, G; Nicolotto, E; Pace, A; Pambuku, A; Pasqualetti, F; Rizzato, S; Rudà, R; Villani, V; Zagonel, V, 2015)
"Our laboratory reported that Irinophore C™ (IrC™; a lipid-based nanoparticulate formulation of irinotecan) is effective against an orthotopic model of glioblastoma (GBM) and that treatment with IrC™ was associated with vascular normalization within the tumor."7.81Determination of an optimal dosing schedule for combining Irinophore C™ and temozolomide in an orthotopic model of glioblastoma. ( Anantha, M; Backstrom, I; Bally, MB; Chu, F; Kalra, J; Masin, D; Strutt, D; Verreault, M; Walker, D; Waterhouse, D; Wehbe, M; Yapp, DT, 2015)
"This study was performed to validate the effectiveness and safety of concurrent chemoradiotherapy and adjuvant therapy with temozolomide for newly diagnosed glioblastoma multiforme as a standard treatment protocol."7.81Validation of the Effectiveness and Safety of Temozolomide during and after Radiotherapy for Newly Diagnosed Glioblastomas: 10-year Experience of a Single Institution. ( Han, JH; Joo, JD; Kim, CY; Kim, H; Kim, YH, 2015)
"Glioblastoma (GBM) generally exhibits high IC50 values for its standard drug treatment, temozolomide (TMZ)."7.81Nanoparticle-Delivered Antisense MicroRNA-21 Enhances the Effects of Temozolomide on Glioblastoma Cells. ( Ananta, JS; Massoud, TF; Paulmurugan, R, 2015)
"Notwithstanding current multimodal treatment, including surgery, radiotherapy and chemotherapy with temozolomide (TMZ), median survival of glioblastoma (GBM) patients is about 14 months, due to the rapid emergence of cell clones resistant to treatment."7.81The histone demethylase KDM5A is a key factor for the resistance to temozolomide in glioblastoma. ( Allemanni, G; Banelli, B; Barbieri, F; Carosio, R; Carra, E; Daga, A; Florio, T; Forlani, A; Marubbi, D; Parodi, F; Pattarozzi, A; Romani, M; Würth, R, 2015)
"Glioma stem cells are associated for temozolomide-resistance in glioblastoma."7.81Co-expression of Cytoskeletal Protein Adducin 3 and CD133 in Neurospheres and a Temozolomide-resistant Subclone of Glioblastoma. ( Leung, GK; Poon, MW; Sun, S; Wong, ST; Zhang, XQ; Zhuang, JT, 2015)
"Temozolomide (TMZ) with radiotherapy is the current standard of care for newly diagnosed glioma."7.81MiR-16 modulate temozolomide resistance by regulating BCL-2 in human glioma cells. ( Chen, Q; Han, J, 2015)
"The standard adjuvant treatment for glioblastoma is temozolomide concomitant with radiotherapy, followed by a further six cycles of temozolomide."7.80Should we continue temozolomide beyond six cycles in the adjuvant treatment of glioblastoma without an evidence of clinical benefit? A cost analysis based on prescribing patterns in Spain. ( Arranz, JL; Balañá, C; Benavides, M; Bugés, C; Cano, JM; de la Peñas, R; García-Bueno, JM; Gil, M; Lopez, D; Martin, JM; Molina-Garrido, MJ; Perez-Segura, P; Rodriguez, A; Sanz, SM; Sepúlveda, JM; Vaz, MA, 2014)
"To assess effectiveness of 5-aminolevulinic acid (5-ALA, Gliolan(®)) in patients treated for malignant glioma under typical daily practice conditions in Spain, using complete resection rate (CR) and progression free survival at 6 months (PFS6)."7.80Observational, retrospective study of the effectiveness of 5-aminolevulinic acid in malignant glioma surgery in Spain (The VISIONA study). ( Arza, C; Díez Valle, R; Galván, J; Romariz, C; Slof, J; Vidal, C, 2014)
"Although temozolomide (TMZ) replaced nitrosoureas as the standard initial chemotherapy for glioblastoma (GBM), no studies have compared TMZ with nimustine (ACNU), a nitrosourea agent widely used in central Europe and most Asian regions."7.80Comparison of the clinical efficacy of temozolomide (TMZ) versus nimustine (ACNU)-based chemotherapy in newly diagnosed glioblastoma. ( Chen, B; Chen, L; Chen, X; Jiang, T; Li, S; Wang, J; Wang, L; Wang, Y; Wu, C; Zhang, X; Zhang, Z, 2014)
"The aim of this study is to investigate the inhibitory effects of 2T-P400, a derivative of temozolomide (TMZ), on glioma growth."7.80The temozolomide derivative 2T-P400 inhibits glioma growth via administration route of intravenous injection. ( Dong, J; Li, R; Tang, D; Wang, L; Wu, J; Zhang, J, 2014)
" This study employed intracranial human glioma models to evaluate the effect of BEV alone and in combination with temozolomide (TMZ) and/or radiation therapy (XRT) on overall survival."7.80Combination of anti-VEGF therapy and temozolomide in two experimental human glioma models. ( Blakeley, JO; Brastianos, H; Brem, H; Goodwin, RC; Grossman, R; Hwang, L; Lal, B; Mangraviti, A; Tyler, B; Wicks, RT; Zadnik, P, 2014)
"Radiation therapy with concomitant and adjuvant temozolomide (TMZ) is the standard therapy for nonelderly patients with glioblastoma."7.80Toxicity and outcome of radiotherapy with concomitant and adjuvant temozolomide in elderly patients with glioblastoma: a retrospective study. ( Mukasa, A; Narita, Y; Saito, K; Saito, N; Shibui, S; Shinoura, N; Tabei, Y, 2014)
"To investigate the mechanisms of action of the tumoricidal effects of temozolomide against the human glioma cell line U251 in vitro, and to provide preclinical proof-of-concept studies of the effects of temozolomide-containing regimens."7.80Mechanism of temozolomide-induced antitumour effects on glioma cells. ( Hu, JA; Shen, W; Zheng, JS, 2014)
"Present work mainly evaluated the inhibitory effects of lidamycin (LDM), an enediyne antibiotic, on angiogenesis or glioma-induced angiogenesis in vitro and in vivo, especially its synergistic anti-angiogenesis with temozolomide (TMZ)."7.80Synergistic inhibition of angiogenesis and glioma cell-induced angiogenesis by the combination of temozolomide and enediyne antibiotic lidamycin. ( Li, XQ; Li, Y; Liu, H; Ouyang, ZG; Shang, Y; Zhang, SH; Zhen, YS, 2014)
"With standard treatment for glioblastoma (GBM) consisting of surgery followed by radiotherapy (RT) with concurrent and adjuvant temozolomide (TMZ), median survival is ~14."7.80Conditional probability of survival and post-progression survival in patients with glioblastoma in the temozolomide treatment era. ( Chung, C; Jiang, H; Laperriere, N; Lwin, Z; Mason, WP; McNamara, MG; Millar, BA; Sahgal, A, 2014)
" In the present study aimed to: (i) evaluate the concordance between MGMT promoter methylation status in tumor tissue and plasma; (ii) monitor MGMT promoter methylation status in plasma taken before and during temozolomide treatment; (iii) explore the value of MGMT promoter methylation status in plasma as a prognostic/predictive biomarker in glioma patients."7.80MGMT promoter methylation in plasma of glioma patients receiving temozolomide. ( Cassoni, P; Castiglione, A; De Marco, L; Fiano, V; Gillio-Tos, A; Grasso, C; Magistrello, M; Merletti, F; Rudà, R; Sacerdote, C; Senetta, R; Soffietti, R; Tondat, F; Trevisan, E; Trevisan, M, 2014)
"Temozolomide profoundly prevented the outgrowth of experimental brain metastases of breast cancer in an MGMT-dependent manner."7.80Profound prevention of experimental brain metastases of breast cancer by temozolomide in an MGMT-dependent manner. ( Biernat, W; Duchnowska, R; Gril, B; Hewitt, SM; Hua, E; Jassem, J; Liewehr, DJ; Palmieri, D; Qian, Y; Sosińska-Mielcarek, K; Stark, AM; Steeg, PS; Steinberg, SM; Woditschka, S, 2014)
"Temozolomide (TMZ), used to treat glioblastoma and malignant glioma, induces autophagy, apoptosis and senescence in cancer cells."7.80Antitumor effect of fibrin glue containing temozolomide against malignant glioma. ( Anai, S; Hide, T; Kuratsu, J; Kuroda, J; Makino, K; Nakamura, H; Shinojima, N; Takezaki, T; Yano, S, 2014)
"Autophagy is a cytoprotective process, which occurs following temozolomide (TMZ) treatment, and contributes to glioma chemoresistance and TMZ treatment failure."7.80Temozolomide induces autophagy via ATM‑AMPK‑ULK1 pathways in glioma. ( Li, B; Wang, Q; Wang, W; Xie, B; Zou, Y, 2014)
" We report a retrospective multicenter study of 97 consecutive adult patients with anaplastic astrocytoma (AA) treated with radiation therapy (RT) plus concomitant and adjuvant temozolomide (TMZ) between October 2004 and March 2012."7.80IDH1 mutation and MGMT methylation status predict survival in patients with anaplastic astrocytoma treated with temozolomide-based chemoradiotherapy. ( Arcella, A; Bozzao, A; Di Stefano, D; Enrici, RM; Esposito, V; Giangaspero, F; Lanzetta, G; Minniti, G; Pace, A; Salvati, M; Scaringi, C; Scarpino, S; Villani, V, 2014)
"Cyclophosphamide-dacarbazine-vincristine regimen is recommended for the treatment of malignant pheochromocytoma and paraganglioma (MPP); however, dacarbazine is the only recognized active drug in neuroendocrine tumours."7.80SDHB mutations are associated with response to temozolomide in patients with metastatic pheochromocytoma or paraganglioma. ( Al Ghuzlan, A; Amar, L; Baudin, E; Bertherat, J; Borget, I; Caramella, C; Chougnet, C; Déandreis, D; Deschamps, F; Dumont, F; Favier, J; Gimenez-Roqueplo, AP; Hadoux, J; Leboulleux, S; Letouzé, E; Libé, R; Loriot, C; Schlumberger, M; Scoazec, JY; Young, J, 2014)
"Glioblastoma multiforme (GBM) represents the most common and deadly primary brain malignancy, particularly due to temozolomide (TMZ) and radiation (RT) resistance."7.80Kinomic exploration of temozolomide and radiation resistance in Glioblastoma multiforme xenolines. ( Anderson, JC; Bonner, JA; Bredel, M; Choradia, NV; Duarte, CW; Rohrbach, TD; Thottassery, JV; Welaya, K; Willey, CD; Yancey Gillespie, G; Yang, ES, 2014)
"Effective sensitizing strategies potentially can extend the benefit of temozolomide (TMZ) therapy in patients with glioblastoma (GBM)."7.80Discordant in vitro and in vivo chemopotentiating effects of the PARP inhibitor veliparib in temozolomide-sensitive versus -resistant glioblastoma multiforme xenografts. ( Bakken, KK; Boakye-Agyeman, F; Carlson, BL; Gupta, SK; Kizilbash, SH; Mladek, AC; Reid, J; Sarkaria, JN; Schroeder, MA, 2014)
"The present work evaluated the synergistic efficacy of an enediyne antibiotic lidamycin (LDM) plus temozolomide (TMZ) against glioma in vitro and in vivo."7.80Synergy of enediyne antibiotic lidamycin and temozolomide in suppressing glioma growth with potentiated apoptosis induction. ( Li, XQ; Li, Y; Liu, H; Ouyang, ZG; Shang, Y; Zhang, SH; Zhen, YS, 2014)
"To study the therapeutic effect of intranasal administration of temozolomide (TMZ) for brain-targeting delivery in a rat model bearing orthotopic C6 glioma xenografts."7.80[Intranasal administration of temozolomide for brain-targeting delivery: therapeutic effect on glioma in rats]. ( Gao, Y; Li, Y; Liu, G; Ma, L; Wang, Y; Zhou, X, 2014)
" The aim of this study was to investigate whether quercetin could sensitize human glioblastoma cells to temozolomide (TMZ) in vitro."7.80Quercetin sensitizes human glioblastoma cells to temozolomide in vitro via inhibition of Hsp27. ( Lan, Q; Li, RJ; Sang, DP, 2014)
"To analyze patterns of failure in patients with glioblastoma multiforme (GBM) treated with limited-margin radiation therapy and concurrent temozolomide."7.80Patterns of failure for glioblastoma multiforme following limited-margin radiation and concurrent temozolomide. ( Bag, AK; Dobelbower, MC; Ennis, WH; Fiveash, JB; Gebhardt, BJ; Markert, JM, 2014)
"We examined changes to key UPR modulators in temozolomide-sensitive and -resistant human GBM cells (D54 and U87) treated with/without temozolomide at different oxygen concentrations using western blotting, and cytotoxic benefits of overexpressing key chaperone, P4HB, in GBM cells (U87 and U251) under normoxia and hyperoxia."7.80Hyperoxia resensitizes chemoresistant glioblastoma cells to temozolomide through unfolded protein response. ( Ho, AS; Kiang, KM; Lee, D; Leung, GK; Sun, S; Xu, FF; Zhang, XQ, 2014)
"This study explored the effects of telomerase reverse transcriptase (TERT) promoter mutations on transcriptional activity of the TERT gene under hypoxic and temozolomide (TMZ) treatment conditions, and investigated the status and prognostic value of these mutations in gliomas."7.80TERT promoter mutations lead to high transcriptional activity under hypoxia and temozolomide treatment and predict poor prognosis in gliomas. ( Chen, C; Han, S; Li, Z; Meng, L; Wu, A; Zhang, X, 2014)
"This study assesses the controversial role of temozolomide (TMZ) concurrent with adjuvant radiation (RT) in patients with anaplastic astrocytoma (AA)."7.80The impact of concurrent temozolomide with adjuvant radiation and IDH mutation status among patients with anaplastic astrocytoma. ( Buckner, JC; Decker, PA; Giannini, C; Hardie, J; Jenkins, RB; Kizilbash, SH; Laack, NN; Parney, IF; Uhm, JH; Voss, JS, 2014)
"This study evaluated the toxicity profiles of temozolomide in the treatment of malignant glioma as either concurrent or adjuvant chemotherapy."7.80Toxicity profile of temozolomide in the treatment of 300 malignant glioma patients in Korea. ( Bae, SH; Cho, SY; Kim, CY; Kim, TM; Kim, YH; Kim, YJ; Lee, MM; Lee, SH; Park, CK; Park, MJ, 2014)
"The combined application of aplysin and TMZ significantly sensitizes glioma cells to TMZ action, compared with TMZ alone."7.80Aplysin enhances temozolomide sensitivity in glioma cells by increasing miR-181 level. ( Ge, N; Gong, A; Liang, H; Lu, L; Yao, W, 2014)
"The aim of the present study was to evaluate the toxicity and clinical outcome of radio-chemotherapy with temozolomide in patients with glioblastoma aged more than 65 years."7.80Radio-chemotherapy with temozolomide in elderly patients with glioblastoma. A mono-institutional experience. ( Cocuzza, P; Fabbrini, MG; Fatigante, L; Ferrazza, P; Monzani, F; Pasqualetti, F; Pasqualetti, G, 2014)
"The current standard of care for glioblastoma (GBM) involves a combination of surgery, radiotherapy, and temozolomide chemotherapy, but this regimen fails to achieve long-term tumor control."7.80Novel MSH6 mutations in treatment-naïve glioblastoma and anaplastic oligodendroglioma contribute to temozolomide resistance independently of MGMT promoter methylation. ( Cairncross, JG; Luchman, HA; Lun, XQ; Nguyen, SA; Robbins, SM; Senger, DL; Stechishin, OD; Weiss, S, 2014)
"To review clinical outcomes of moderate dose escalation using high-dose radiation therapy (HDRT) in the setting of concurrent temozolomide (TMZ) in patients with newly diagnosed glioblastoma multiforme (GBM), compared with standard-dose radiation therapy (SDRT)."7.80Radiation therapy dose escalation for glioblastoma multiforme in the era of temozolomide. ( Badiyan, SN; Chicoine, MR; Dacey, R; DeWees, T; Dowling, JL; Huang, J; Jalalizadeh, R; Kim, AH; Leuthardt, EC; Linette, G; Markovina, S; Rich, KM; Robinson, CG; Simpson, JR; Tran, DD; Zipfel, GJ, 2014)
"These results suggest that concomitant treatment with NPe6-PDT and temozolomide is a potentially useful therapy for glioma."7.80Concomitant treatment with temozolomide enhances apoptotic cell death in glioma cells induced by photodynamic therapy with talaporfin sodium. ( Akimoto, J; Beppu, M; Fujiwara, Y; Hiranuma, M; Hironaka, C; Miki, Y; Moritake, K; Omata, H, 2014)
"We report the safety and feasibility of a 3 days on/11 days off temozolomide regimen for the treatment of recurrent malignant gliomas."7.80Retrospective analysis of safety and feasibility of a 3 days on/11 days off temozolomide dosing regimen in recurrent adult malignant gliomas. ( Brown, BD; Brown, T; Juarez, T; Kesari, S; Piccioni, DE; Saria, MG; van Vugt, VA, 2014)
"To assess the prognosis predictability of a measurable enhancing lesion using histogram parameters produced by the normalized cerebral blood volume (nCBV) and normalized apparent diffusion coefficient (nADC) after completion of standard concomitant chemoradiotherapy (CCRT) and adjuvant temozolomide (TMZ) medication in glioblastoma multiforme (GBM) patients."7.80Prognosis prediction of measurable enhancing lesion after completion of standard concomitant chemoradiotherapy and adjuvant temozolomide in glioblastoma patients: application of dynamic susceptibility contrast perfusion and diffusion-weighted imaging. ( Choi, SH; Kim, IH; Kim, JH; Kim, TM; Lee, SH; Park, CK; Park, SH; Ryoo, I; Sohn, CH; Yun, TJ, 2014)
"Temozolomide, an oral alkylating agent, is used in the treatment of glioblastoma."7.80Vanishing bile duct syndrome in the context of concurrent temozolomide for glioblastoma. ( Adeyi, O; Fung, S; Mason, M; Millar, BA, 2014)
"The objective of this study was to report the authors' experience with the long-term administration of temozolomide (TMZ; > 6 cycles, up to 101) in patients with newly diagnosed glioblastoma and to analyze its feasibility and safety as well as its impact on survival."7.80Long-term therapy with temozolomide is a feasible option for newly diagnosed glioblastoma: a single-institution experience with as many as 101 temozolomide cycles. ( Albanese, V; Barbagallo, GM; Caltabiano, R; Certo, F; Lanzafame, S; Longo, A; Motta, F; Palmucci, S; Paratore, S; Parra, HS; Privitera, G; Scaglione, G, 2014)
"For glioma, temozolomide (TMZ) is a commonly used chemotherapy drug and photodynamic therapy (PDT) is an important adjuvant therapy."7.80Combination of photodynamic therapy and temozolomide on glioma in a rat C6 glioma model. ( Guo, M; Hu, S; Shen, L; Zhang, X, 2014)
"Nine post-temozolomide recurrent or progressive high-grade glioma patients (seven with glioblastoma and two with anaplastic astrocytoma) were treated with BV monotherapy."7.80Predictive significance of mean apparent diffusion coefficient value for responsiveness of temozolomide-refractory malignant glioma to bevacizumab: preliminary report. ( Kobayashi, K; Nagane, M; Shimizu, S; Shiokawa, Y; Shishido-Hara, Y; Tanaka, M; Tsuchiya, K, 2014)
"The benefit of the introduction of alkylating chemotherapy in the treatment of glioblastoma multiforme (GBM) patients has been demonstrated by comparing radiotherapy with concomitant plus intermittent temozolomide (iTMZ) to radiation therapy."7.79The impact of sequential vs. combined radiochemotherapy with temozolomide, resection and MGMT promoter hypermethylation on survival of patients with primary glioblastoma--a single centre retrospective study. ( Felsberg, J; Goeppert, M; Rapp, M; Sabel, M; Steiger, HJ, 2013)
" In this study, we investigated the predictive value of SLC22A18 promoter methylation and protein expression in glioblastoma multiforme (GBM) patients receiving temozolomide (TMZ) therapy."7.79Predictive value of the SLC22A18 protein expression in glioblastoma patients receiving temozolomide therapy. ( Chu, SH; Feng, DF; Jiang, PC; Li, ZQ; Ma, YB, 2013)
"Temozolomide (TMZ) is commonly used in the treatment of glioblastoma (GBM)."7.79Effect of lomeguatrib-temozolomide combination on MGMT promoter methylation and expression in primary glioblastoma tumor cells. ( Canpinar, H; Castresana, JS; Ilgaz, S; Ozdemir, M; Ozkan, T; Oztuna, D; Rey, JA; Sunguroğlu, A; Taspinar, M; Ugur, HC, 2013)
"Valproic acid (VA) is an antiepileptic drug (AED) and histone deacetylase (HDAC) inhibitor taken by patients with glioblastoma (GB) to manage seizures, and it can modulate the biologic effects of radiation therapy (RT)."7.79Valproic acid use during radiation therapy for glioblastoma associated with improved survival. ( Barker, CA; Beal, K; Bishop, AJ; Chan, TA; Chang, M, 2013)
"The purpose of this study is to assess the preclinical therapeutic efficacy of magnetic resonance imaging (MRI)-monitored focused ultrasound (FUS)-induced blood-brain barrier (BBB) disruption to enhance Temozolomide (TMZ) delivery for improving Glioblastoma Multiforme (GBM) treatment."7.79Focused ultrasound-induced blood-brain barrier opening to enhance temozolomide delivery for glioblastoma treatment: a preclinical study. ( Chen, PY; Chu, PC; Feng, LY; Hsu, PW; Huang, CY; Lee, PY; Liu, HL; Lu, YJ; Tsai, HC; Tseng, IC; Wang, HY; Wei, KC; Yen, TC, 2013)
"We investigated the pattern of failure in glioblastoma multiforma (GBM) patients treated with concurrent radiation, bevacizumab (BEV), and temozolomide (TMZ)."7.79Concurrent bevacizumab and temozolomide alter the patterns of failure in radiation treatment of glioblastoma multiforme. ( Kadner, R; Shields, LB; Spalding, AC; Vitaz, TW, 2013)
"We have studied the consequences of the combination of the mammalian target of rapamycin (mTOR) inhibitor RAD001 and temozolomide on the growth and cell death of the glioblastoma cell line U-87 in vitro."7.79The mTOR inhibitor RAD001 potentiates autophagic cell death induced by temozolomide in a glioblastoma cell line. ( Bischoff, P; Burckel, H; Josset, E; Noël, G, 2013)
"To determine whether immediate post-operative brachytherapy can be safely applied to newly diagnosed glioblastomas to retard tumor progression prior to initiation of external beam radiation therapy (EBRT) and temozolomide."7.79Immediate post-operative brachytherapy prior to irradiation and temozolomide for newly diagnosed glioblastoma. ( Alksne, JF; Carter, BS; Chen, CC; Gonda, DD; Lawson, J; Murphy, K; Rose, B; Russell, M; Scanderbeg, DJ; Waters, JD, 2013)
"To examine the efficacy of valproic acid (VPA) given either with or without levetiracetam (LEV) on seizure control and on survival in patients with glioblastoma multiforme (GBM) treated with chemoradiation."7.79Effect of valproic acid on seizure control and on survival in patients with glioblastoma multiforme. ( Dielemans, JC; Kerkhof, M; Taphoorn, MJ; van Breemen, MS; Vecht, CJ; Walchenbach, R; Zwinkels, H, 2013)
"Global gene expressions and drug sensitivities to three chemotherapeutic drugs (imatinib, camptothecin and temozolomide) were measured in six human glioblastoma-derived cell lines."7.79Synergistic interactions between camptothecin and EGFR or RAC1 inhibitors and between imatinib and Notch signaling or RAC1 inhibitors in glioblastoma cell lines. ( Andersson, C; Bergqvist, M; Blomquist, E; Ekman, S; Gullbo, J; Isaksson, A; Johansson, F; Kultima, HG; Lennartsson, J; Sooman, L, 2013)
"To explore the role of histogram analysis of apparent diffusion coefficient (ADC) maps obtained at standard- and high-b-value (1000 and 3000 sec/mm(2), respectively) diffusion-weighted (DW) imaging in the differentiation of true progression from pseudoprogression in glioblastoma treated with radiation therapy and concomitant temozolomide."7.79Differentiation of true progression from pseudoprogression in glioblastoma treated with radiation therapy and concomitant temozolomide: comparison study of standard and high-b-value diffusion-weighted imaging. ( Choi, SH; Chu, HH; Jung, SC; Kim, IH; Kim, JH; Kim, SC; Kim, TM; Lee, AL; Lee, SH; Park, CK; Park, SH; Ryoo, I; Shin, H; Sohn, CH; Yeom, JA; Yoon, TJ, 2013)
"Glioblastomas are the most frequent and aggressive intracranial neoplasms in humans, and despite advances and the introduction of the alkylating agent temozolomide in therapy have improved patient survival, resistance mechanisms limit benefits."7.79Extracellular sphingosine-1-phosphate: a novel actor in human glioblastoma stem cell survival. ( Caroli, M; Condomitti, G; Di Vito, C; Galli, R; Giussani, P; Riboni, L; Riccitelli, E; Tringali, C; Viani, P, 2013)
"To evaluate the efficacy of pulsed low-dose radiation therapy (PLRT) combined with temozolomide (TMZ) as a novel treatment approach for radioresistant glioblastoma multiforme (GBM) in a murine model."7.79Pulsed versus conventional radiation therapy in combination with temozolomide in a murine orthotopic model of glioblastoma multiforme. ( Chunta, JL; Grills, IS; Huang, J; Krueger, SA; Lee, DY; Marples, B; Martinez, AA; Park, SS; Wilson, GD, 2013)
"Addition of temozolomide (TMZ) to radiation therapy is the standard treatment for patients with glioblastoma (GBM)."7.79Early assessment of the efficacy of temozolomide chemotherapy in experimental glioblastoma using [18F]FLT-PET imaging. ( Faber, C; Jacobs, AH; Kopka, K; Kuhlmann, M; Schäfers, M; Schelhaas, S; Schwegmann, K; Viel, T; Wachsmuth, L; Wagner, S, 2013)
" Such chemoresistance was overcome by apparently noncytotoxic doses of temozolomide, which chemosensitized glioblastoma cells to doxorubicin, vinblastine, and etoposide."7.79Temozolomide downregulates P-glycoprotein expression in glioblastoma stem cells by interfering with the Wnt3a/glycogen synthase-3 kinase/β-catenin pathway. ( Annovazzi, L; Bosia, A; Caldera, V; Campia, I; Ghigo, D; Kopecka, J; Mellai, M; Riganti, C; Salaroglio, IC; Schiffer, D, 2013)
"Radiotherapy with concomitant and adjuvant temozolomide (six cycles) is the standard treatment after surgery in glioblastoma patients."7.79Prolonged administration of adjuvant temozolomide improves survival in adult patients with glioblastoma. ( Baumann, C; Beauchesne, P; Blonski, M; Chauffert, B; Darlix, A; Ghiringhelli, F; Lorgis, V; Pinelli, C; Rech, F; Taillandier, L; Zouaoui, S, 2013)
"To compare retrospectively outcome after photon radiotherapy alone, radiochemotherapy with temozolomide (TMZ), and carbon ion radiotherapy in patients with high-grade gliomas and to generate a hypothetical outcome curve for C12 and TMZ."7.79Comparison of carbon ion radiotherapy to photon radiation alone or in combination with temozolomide in patients with high-grade gliomas: explorative hypothesis-generating retrospective analysis. ( Bruckner, T; Combs, SE; Debus, J; Kamada, T; Kieser, M; Mizoe, JE; Tsujii, H, 2013)
"The recent progress in chemotherapy for malignant gliomas is attributable to the introduction of the DNA-methylating agent temozolomide (TMZ); however, drug resistance remains a major issue."7.79The Cdk inhibitor flavopiridol enhances temozolomide-induced cytotoxicity in human glioma cells. ( Adachi, K; Hayashi, T; Hirose, Y; Ohba, S, 2013)
" Temozolomide (TMZ) with radiation is the most frequently used first-line treatment for patients with glioblastoma, the most common and aggressive form of primary brain cancer in adults."7.79Toca 511 gene transfer and 5-fluorocytosine in combination with temozolomide demonstrates synergistic therapeutic efficacy in a temozolomide-sensitive glioblastoma model. ( Espinoza, FL; Gruber, HE; Gunzburg, W; Hlavaty, J; Huang, TT; Ibañez, CE; Jolly, DJ; Kasahara, N; Martin, B; Ostertag, D; Pertschuk, D; Petznek, H; Robbins, JM; Rodriguez-Aguirre, M, 2013)
"Temozolomide (TMZ) during and after radiotherapy (RT) is recommended for patients with newly diagnosed glioblastoma (GBM)."7.79Glioblastoma management in the temozolomide era: have we improved outcome? ( Al-Zahrani, A; Atenafu, E; Laperriere, N; Lwin, Z; MacFadden, D; Mason, WP; Menard, C; Miller, BA; Sahgal, A, 2013)
"The effect of concomitant and adjuvant temozolomide in glioblastoma patients above the age of 65 years lacks evidence."7.79Concomitant and adjuvant temozolomide of newly diagnosed glioblastoma in elderly patients. ( Behm, T; Bock, HC; Horowski, A; Mielke, D; Rohde, V; Schneider, S; Stockhammer, F, 2013)
"In 2005, maximum safe surgical resection, followed by radiotherapy with concomitant temozolomide (TMZ), followed by adjuvant TMZ became the standard of care for glioblastoma (GBM)."7.79Time trends in glioblastoma multiforme survival: the role of temozolomide. ( Darefsky, AS; Dubrow, R; Jacobs, DI; King, JT; Laurans, MS; Park, LS; Rose, MG, 2013)
"To examine whether adjuvant temozolomide treatment improved glioblastoma patients` survival in a large Canadian cohort."7.79Effectiveness of adjuvant temozolomide treatment in patients with glioblastoma. ( Al-Nuaimi, SK; Alnaami, IM; Gourishankar, S; Mehta, V; Murtha, AD; Senthilselvan, A; Walling, S, 2013)
"To analyze initial recurrence patterns in patients with newly diagnosed glioblastoma after radiotherapy plus concurrent and adjuvant temozolomide, and to investigate cumulative recurrence patterns after salvage treatment, including surgery, stereotactic radiotherapy, and chemotherapy."7.79Initial and cumulative recurrence patterns of glioblastoma after temozolomide-based chemoradiotherapy and salvage treatment: a retrospective cohort study in a single institution. ( Arakawa, Y; Hiraoka, M; Miyamoto, S; Mizowaki, T; Ogura, K; Ogura, M; Sakanaka, K, 2013)
" Here, we report for the first time that the second mitochondria-derived activator of caspases (Smac) mimetic BV6 sensitizes glioblastoma cells toward Temozolomide (TMZ), the first-line chemotherapeutic agent in the treatment of glioblastoma."7.79Smac mimetic sensitizes glioblastoma cells to Temozolomide-induced apoptosis in a RIP1- and NF-κB-dependent manner. ( Cristofanon, S; Debatin, KM; Deshayes, K; Fulda, S; Karl, S; Marschall, V; Vucic, D; Wagner, L; Zobel, K, 2013)
" We retrospectively surveyed 32 patients with GBM or GBM with oligodendroglioma component (GBMO) who underwent biopsy or maximal tumor resection followed by concurrent radiotherapy and temozolomide (TMZ)."7.79IDH1 mutation as a potential novel biomarker for distinguishing pseudoprogression from true progression in patients with glioblastoma treated with temozolomide and radiotherapy. ( Houkin, K; Kamoshima, Y; Kobayashi, H; Motegi, H; Murata, J; Tanino, M; Terasaka, S; Yamaguchi, S, 2013)
"We investigated whether high levels of activated mitogen-activated protein kinase (p-MAPK) were associated with poor survival among patients with newly diagnosed glioblastoma during the temozolomide era."7.79High levels of phosphorylated MAP kinase are associated with poor survival among patients with glioblastoma during the temozolomide era. ( Bannykh, SI; Black, KL; Carico, C; Dantis, J; Elramsisy, A; Fan, X; Hu, J; Mukherjee, D; Nuño, M; Patil, CG; Yu, JS, 2013)
" This study aimed to investigate the possible mechanism of mutant TP53 inducing temozolomide resistance in glioblastoma cells."7.79Mutant TP53 enhances the resistance of glioblastoma cells to temozolomide by up-regulating O(6)-methylguanine DNA-methyltransferase. ( Chen, JX; Liu, YH; Mao, Q; Wang, X; You, C, 2013)
" In previous studies the alkylating agent temozolomide (TMZ) incorporated into a polymer, pCPP:SA, also for local delivery, and OncoGel were individually shown to increase efficacy in a rat glioma model."7.79Combination of paclitaxel thermal gel depot with temozolomide and radiotherapy significantly prolongs survival in an experimental rodent glioma model. ( Brem, H; Eberhart, CG; Fowers, KD; Hwang, L; Li, KW; Okonma, S; Recinos, VR; Tyler, BM; Vellimana, AK; Zhang, Y, 2013)
"To compare survival and hematological toxicity rates between two postoperative therapy regimens in patients with primary glioblastoma (GBM), namely temozolomide (TMZ) concomitant to radiation, followed by adjuvant TMZ, versus adjuvant TMZ after radiation only."7.79Toxicity and survival in primary glioblastoma patients treated with concomitant plus adjuvant temozolomide versus adjuvant temozolomide: results of a single-institution, retrospective, matched-pair analysis. ( Bock, HC; Brück, W; Giese, A; Gutenberg, A; Reifenberger, G, 2013)
"We retrospectively reviewed nine cases of relapsed medulloblastoma treated with bevacizumab, irinotecan, ± temozolomide."7.79Response to bevacizumab, irinotecan, and temozolomide in children with relapsed medulloblastoma: a multi-institutional experience. ( Aguilera, D; Castellino, RC; Fangusaro, J; Hayes, LL; Kim, S; MacDonald, TJ; Mazewski, C; McNall-Knapp, RY, 2013)
"For elderly patients with glioblastoma multiforme (GBM), radiotherapy plus concomitant and adjuvant temozolomide has resulted in longer survival."7.79Performance status during and after radiotherapy plus concomitant and adjuvant temozolomide in elderly patients with glioblastoma multiforme. ( Jang, WY; Jeong, EH; Jung, S; Jung, TY; Kim, IY; Lee, JH; Moon, KS, 2013)
"To evaluate pathologically confirmed incidence of pseudoprogression and its impact on survival in glioblastoma multiforme (GBM) patients treated with radiotherapy and concurrent temozolomide (TMZ), followed by 6 months of TMZ maintenance therapy."7.78Pseudoprogression in patients with glioblastoma multiforme after concurrent radiotherapy and temozolomide. ( Oymak, E; Parlak, C; Pehlivan, B; Topkan, E; Topuk, S, 2012)
"We report retrospective data on the feasibility and efficacy of prolonging adjuvant temozolomide (TMZ) more than 6 months after chemoradiotherapy completion in patients with glioblastoma (GBM)."7.78Prolonged temozolomide for treatment of glioblastoma: preliminary clinical results and prognostic value of p53 overexpression. ( Auberdiac, P; Cartier, L; Chargari, C; Forest, F; Fotso, MJ; Magné, N; Malkoun, N; Nuti, C; Pacaut, C; Peoc'h, M; Schmitt, T; Thorin, J, 2012)
"Temozolomide (TMZ) is given in addition to radiotherapy in glioma patients, but its interaction with the commonly prescribed antiepileptic drug valproic acid (VPA) is largely unknown."7.78Valproic acid sensitizes human glioma cells for temozolomide and γ-radiation. ( Lafleur, MV; Slotman, BJ; Sminia, P; Stalpers, LJ; Van den Berg, J; Van Nifterik, KA, 2012)
"The standard-of-care treatment for newly diagnosed glioblastoma changed in 2005, when radiation therapy plus temozolomide chemotherapy replaced radiation therapy alone."7.78Glioblastoma survival in the United States before and during the temozolomide era. ( Johnson, DR; O'Neill, BP, 2012)
"To determine the maximum-tolerated dose (MTD) of radiation (RT) with concurrent temozolomide in patients with newly diagnosed glioblastoma (GBM), to estimate their progression-free (PFS) and overall survival (OS), and to assess the role of (11)C methionine PET (MET-PET) imaging in predicting recurrence."7.78Concurrent temozolomide and dose-escalated intensity-modulated radiation therapy in newly diagnosed glioblastoma. ( Brown, D; Cao, Y; Chenevert, T; Gomez-Hassan, D; Heth, J; Junck, L; Lawrence, T; Normolle, D; Piert, M; Schipper, M; Ten Haken, RK; Tsien, CI, 2012)
"The alkylating agent temozolomide (TMZ) is the major chemotherapeutic drug used clinically in the treatment of malignant gliomas."7.78Resveratrol enhances the therapeutic effect of temozolomide against malignant glioma in vitro and in vivo by inhibiting autophagy. ( Lee, CC; Lin, CJ; Lin, TY; Lin, YF; Shih, CM; Shih, YL; Wang, SH, 2012)
"The standard of care for newly diagnosed glioblastoma multiforme (GBM) is temozolomide (TMZ) chemotherapy given concurrently with radiation for 6 weeks followed by 6 months of adjuvant TMZ."7.78Extended adjuvant temozolomide for treatment of newly diagnosed glioblastoma multiforme. ( Easaw, JC; Roldán Urgoiti, GB; Singh, AD, 2012)
"Alkylating agents, such as temozolomide (TMZ) and fotemustine (FTM) are widely used in recurrent glioblastoma (GBM) regimes."7.78Twice-daily dosing of temozolomide in combination with fotemustine for the treatment of patients with refractory glioblastoma. ( Burattini, L; Cascinu, S; Onofri, A; Paccapelo, A; Santoni, M, 2012)
"Polysorbate 80 coated temozolomide-loaded PLGA-based superparamagnetic nanoparticles (P80-TMZ/SPIO-NPs) were successfully synthesized and characterized as drug carriers and diagnosis agent for malignant brain glioma."7.78Temozolomide loaded PLGA-based superparamagnetic nanoparticles for magnetic resonance imaging and treatment of malignant glioma. ( Ling, Y; Wei, K; Zhong, S; Zou, F, 2012)
"Interferon-beta (IFN-β) is reported to augment anti-tumor effects by temozolomide in glioblastoma via down-regulation of MGMT."7.78Up-regulation of endogenous PML induced by a combination of interferon-beta and temozolomide enhances p73/YAP-mediated apoptosis in glioblastoma. ( Hara, K; Kageji, T; Kitazato, KT; Kuwayama, K; Matsuzaki, K; Mizobuchi, Y; Morigaki, R; Mure, H; Nagahiro, S; Okazaki, T, 2012)
"The effectiveness of temozolomide (TMZ) dosing schemes and the "rechallenge" of recurrent glioblastoma (GBM) with TMZ are controversial."7.78Efficacy of clinically relevant temozolomide dosing schemes in glioblastoma cancer stem cell lines. ( Beier, CP; Beier, D; Brawanski, K; Hau, P; Schriefer, B; Schulz, JB; Weis, J, 2012)
"Temozolomide (TMZ) is an alkylating chemotherapeutic agent that prolongs the survival of patients with glioblastoma."7.78Distinct molecular mechanisms of acquired resistance to temozolomide in glioblastoma cells. ( Florea, AM; Happold, C; Reifenberger, G; Roth, P; Schmidt, N; Silginer, M; Weller, M; Wick, W, 2012)
"We analyzed the usefulness of initial or recurrent treatment of temozolomide (TMZ) in pediatric high-grade gliomas (HGGs)."7.78Prognosis of pediatric high-grade gliomas with temozolomide treatment: a retrospective, multicenter study. ( Baek, HJ; Choi, HS; Jung, TY; Kim, CY; Kim, DS; Kim, IA; Kim, SH; Ra, YS, 2012)
"Radiotherapy plus concomitant and adjuvant temozolomide (RCAT) is now standard treatment for grade IV glioblastoma (GBM)."7.78Change in platelet levels during radiotherapy with concurrent and adjuvant temozolomide for the treatment of glioblastoma: a novel prognostic factor for survival. ( Hargreaves, S; Kooner, I; Liu, ZW; Menashy, R; Michalarea, V; Williams, M; Wilson, E; Woolf, D, 2012)
"The combination of hyperbaric oxygen with temozolomide produced an important reduction in glioma growth and effective approach to the treatment of glioblastoma."7.78Combination hyperbaric oxygen and temozolomide therapy in C6 rat glioma model. ( Bilir, A; Bozkurt, ER; Dagıstan, Y; Karaca, I; Ozar, E; Toklu, A; Yagmurlu, K, 2012)
"Temozolomide (TMZ) has become a key therapeutic agent in patients with malignant gliomas; however, its survival benefit remains unsatisfactory."7.78Valproic acid downregulates the expression of MGMT and sensitizes temozolomide-resistant glioma cells. ( Hou, Y; Jeong, CH; Jeun, SS; Kim, SM; Lim, JY; Park, KY; Ryu, CH; Woo, JS; Yoon, WS, 2012)
"Temozolomide (TMZ) is standard chemotherapy for glioblastoma multiforme (GBM)."7.78Hyperoxia resensitizes chemoresistant human glioblastoma cells to temozolomide. ( Fung, CF; Lee, D; Lee, NP; Leung, GK; Lui, WM; Pu, JK; Sun, S; Wong, ST, 2012)
"Currently, treatment of malignant gliomas with temozolomide in addition to surgical resection and radiotherapy remains the foundation of glioma therapy."7.78Local delivery of slow-releasing temozolomide microspheres inhibits intracranial xenograft glioma growth. ( Chen, Y; Cui, B; Dai, X; Dong, J; Huang, Q; Lan, Q; Tang, D; Zhang, J; Zhou, G, 2012)
"The effect of temozolomide (TMZ) and radiotherapy (RT) in the treatment of glioblastoma multiforme (GBM) has been well documented in randomized controlled trials."7.78A population-based study on the effect of temozolomide in the treatment of glioblastoma multiforme. ( Helseth, E; Johannesen, TB; Meling, TR; Rønning, PA, 2012)
"Temozolomide (TMZ) is an oral alkylating agent widely used in the treatment of refractory glioma."7.78The synergistic therapeutic effect of temozolomide and hyperbaric oxygen on glioma U251 cell lines is accompanied by alterations in vascular endothelial growth factor and multidrug resistance-associated protein-1 levels. ( Cao, K; Li, QY; Lu, PS; Lu, XY; Yuan, ZC, 2012)
" Recently, in a phase II trial in Brazil for the treatment of temozolomide (TMZ)-resistant malignant gliomas, POH was well tolerated when administered intranasally."7.78Perillyl alcohol for the treatment of temozolomide-resistant gliomas. ( Chen, TC; Cho, HY; Goldkorn, A; Hofman, FM; Jhaveri, N; Lee, DJ; Leong, MN; Louie, SG; Petasis, NA; Schönthal, AH; Torres, S; Tseng, J; Wang, W; Xu, T, 2012)
"Treatment of patients with glioblastoma improved dramatically when concomitant and adjuvant temozolomide was added to external radiation therapy."7.78A review of dose-dense temozolomide alone and in combination with bevacizumab in patients with first relapse of glioblastoma. ( Bergqvist, M; Bergström, S; Blomquist, E; Ekman, S; Henriksson, R; Johansson, F, 2012)
"Implementation of chemotherapy with the drug temozolomide increased the overall survival of patients with glioblastoma multiforme (GBM; WHO grade IV), in particular when the O(6)-methylguanine DNA methyltransferase (MGMT) promoter is epigenetically silenced."7.78Aldehyde dehydrogenase 1A1--a new mediator of resistance to temozolomide in glioblastoma. ( Beier, CP; Bettstetter, M; Gempt, J; Hoepner, I; Koeritzer, J; Meyer, B; Rasper, M; Ringel, F; Schäfer, A; Schlegel, J; Schmidt-Graf, F; Teufel, J, 2012)
"Implantable and poly (d,l-lactide-co-glycolide) (PLGA) microparticles were developed to deliver temozolomide (TM) continuously in interstitial chemotherapy for glioma."7.77Temozolomide/PLGA microparticles: a new protocol for treatment of glioma in rats. ( Liu, JM; Yue, ZJ; Zhang, H; Zhang, YH, 2011)
"We analyzed 62 consecutive patients with newly diagnosed glioblastoma treated between 2006 and 2008 with standard fractionation to a total dose of 60 Gy with concurrent temozolomide (97%) or arsenic trioxide (3%)."7.77Pattern of failure after limited margin radiotherapy and temozolomide for glioblastoma. ( Crocker, IR; Curran, WJ; McDonald, MW; Shu, HK, 2011)
"We investigated pseudoprogression (psPD) in patients with malignant gliomas treated with radiotherapy (RT) and maintenance temozolomide (TMZ) in terms of incidence, outcomes, and predictive and prognostic factors."7.77Pseudoprogression in patients with malignant gliomas treated with concurrent temozolomide and radiotherapy: potential role of p53. ( Choe, GY; Han, JH; Kang, HC; Kim, CY; Kim, IA; Kim, JH, 2011)
"To evaluate the safety and efficacy of hypofractionated radiotherapy (RT) with a standard temozolomide (TMZ) regimen for adults with newly diagnosed glioblastoma multiforme (GBM), twenty-six consecutive adults (range 39-79 years) who met our enrollment criteria received short courses of hypofractionated RT (45 Gy in 15 fractions over three weeks) with concomitant TMZ at 75 mg/m(2)/d."7.77A pilot study of hypofractionated radiation therapy with temozolomide for adults with glioblastoma multiforme. ( Eto, T; Nakashima, S; Ogo, E; Okada, Y; Shigemori, M; Sugita, Y; Terasaki, M; Tokutomi, T, 2011)
" A 56-year-old man with a left parietal glioblastoma was treated with resection, radiation and concomitant and adjuvant temozolomide chemotherapy."7.77Kitten-transmitted Bordetella bronchiseptica infection in a patient receiving temozolomide for glioblastoma. ( Grommes, C; Papanicolaou, G; Redelman-Sidi, G, 2011)
"Temozolomide in combination with radiation has been in use for more than 5 years for the therapy of glioblastoma."7.77Hepatic encephalopathy after treatment with temozolomide. ( Goldbecker, A; Herrmann, J; Raab, P; Tryc, AB; Weissenborn, K; Worthmann, H, 2011)
"Patients with non-resectable glioblastoma generally exhibit a poor prognosis, even after radiotherapy plus concomitant and adjuvant temozolomide (XRT/TMZ→TMZ)."7.77Predominant influence of MGMT methylation in non-resectable glioblastoma after radiotherapy plus temozolomide. ( Belka, C; Eigenbrod, S; Grasbon-Frodl, EM; Kreth, FW; Kreth, S; Kretzschmar, HA; Lutz, J; Popperl, G; Thon, N; Tonn, JC, 2011)
"This prospective study was performed to determine the efficacy, safety, and tolerability of concurrent chemoradiotherapy (CCRT) followed by adjuvant chemotherapy with temozolomide (TMZ) in the treatment of patients with WHO grade III gliomas."7.77Temozolomide during and after radiation therapy for WHO grade III gliomas: preliminary report of a prospective multicenter study. ( Bae, SH; Cha, SH; Cho, WH; Choe, G; Jung, HW; Kim, CY; Kim, DG; Kim, IA; Kim, IH; Kim, YH; Lee, MM; Moon, S; Park, CK; Park, SH, 2011)
"The aim of this paper is to evaluate the efficacy of fractionated stereotactic radiotherapy (FSRT) and concomitant temozolomide (TMZ) as a salvage treatment option in patients with recurrent glioblastoma (GBM)."7.77Fractionated stereotactic reirradiation and concurrent temozolomide in patients with recurrent glioblastoma. ( Armosini, V; Caporello, P; Lanzetta, G; Maurizi, RE; Mei, M; Minniti, G; Osti, MF; Salvati, M, 2011)
"Only a few studies examined the effect of temozolomide (TMZ) in recurrent low-grade astrocytoma (LGA) after surgery, none of which included a homogeneous and sufficiently sized group of patients with progression after radiotherapy (RT)."7.77First-line temozolomide chemotherapy in progressive low-grade astrocytomas after radiotherapy: molecular characteristics in relation to response. ( Boogerd, W; Bromberg, JE; Dinjens, WN; Dubbink, HJ; Gijtenbeek, JM; Groenendijk, FH; Kouwenhoven, MC; Kros, JM; Postma, TJ; Sillevis Smitt, PA; Taal, W; van den Bent, MJ; van der Holt, B; van Heuvel, I; van Marion, R; Zonnenberg, BA; Zonnenberg, CB, 2011)
"The alkylating agent temozolomide, in combination with surgery and radiation, is the current standard of care for patients with glioblastoma."7.77Green tea epigallocatechin gallate enhances therapeutic efficacy of temozolomide in orthotopic mouse glioblastoma models. ( Chen, TC; Golden, EB; Hofman, FM; Louie, SG; Schönthal, AH; Sivakumar, W; Thomas, S; Wang, W, 2011)
" Induction of autophagy by temozolomide (TMZ) has been noted in glioma cell lines."7.77Induction of autophagy in temozolomide treated malignant gliomas. ( Aoki, H; Fujii, Y; Kakita, A; Miyahara, H; Natsumeda, M; Takahashi, H; Toyoshima, Y; Uzuka, T; Yajima, N, 2011)
"Concomitant radiation therapy (RT) and temozolomide (TMZ) therapy after surgery is the standard treatment for glioblastoma multiforme (GBM)."7.77Immune modulation effects of concomitant temozolomide and radiation therapy on peripheral blood mononuclear cells in patients with glioblastoma multiforme. ( Côté, AL; Ernstoff, MS; Fadul, CE; Fisher, JL; Gui, J; Hampton, TH, 2011)
"Temozolomide (TMZ) is the preferred chemotherapeutic agent in the treatment of glioma following surgical resection and/or radiation."7.77N-methylpurine DNA glycosylase and DNA polymerase beta modulate BER inhibitor potentiation of glioma cells to temozolomide. ( Banze, LA; Brown, AR; Goellner, EM; Hamilton, RL; Moore, B; Sobol, RW; Svilar, D; Tang, JB; Trivedi, RN; Wang, XH, 2011)
" Corticorelin acetate (Xerecept) or human corticotrophin-releasing factor (hCRF) is a comparatively new drug and has been evaluated in two orthotopic glioma models (U87 and C6), by a direct comparison with dexamethasone and temozolomide."7.77Comparison of corticotropin-releasing factor, dexamethasone, and temozolomide: treatment efficacy and toxicity in U87 and C6 intracranial gliomas. ( Blasberg, RG; de Stanchina, E; Gamez, I; Huang, R; Kochetkov, T; Moroz, MA; Ryan, RP; Shi, W; Thaler, H, 2011)
"We investigated the molecular mechanisms underlying the cytotoxic effect of Temozolomide (TMZ) in both O(6)-methylguanine-DNA methyl transferase (MGMT) depleted as well as undepleted glioblastoma cell lines."7.77Temozolomide induced c-Myc-mediated apoptosis via Akt signalling in MGMT expressing glioblastoma cells. ( Brunetti, E; Bucci, B; D'agnano, I; De Paula, U; De Salvo, M; Gagliassi, R; Marchese, R; Maresca, G; Raza, GH; Stigliano, A, 2011)
"To study the impact of two human glioma tissue resistance genes MGMT and ERCC(2) on the temozolomide-based treatment of malignant gliomas and detect the relationship of their expressions."7.77[Comparison of MGMT and ERCC₂ expression in temozolomide for the treatment of malignant glioma drug resistance and their genetic relationship]. ( Hou, X; Sun, JH; Wang, JJ; Wu, ZC; Zhao, Y; Zheng, YR, 2011)
"Temozolomide has significantly improved the outcome of patients with glioblastoma."7.77[Benefit of a prolonged adjuvant treatment with temozolomide for the management of patients with glioblastoma]. ( Auberdiac, P; Cartier, L; Chargari, C; Forest, F; Fotso, MJ; Magné, N; Malkoun, N; Nuti, C; Pacaut, C; Peoc'h, M; Schmitt, T; Thorin, J, 2011)
"Temozolomide (TMZ), an alkylating agent widely used for patients with glioblastoma multiforme (GBM), has the potential to enhance the acquired immune response to GBM."7.77Pathological changes after autologous formalin-fixed tumor vaccine therapy combined with temozolomide for glioblastoma - three case reports - . ( Enomoto, T; Ishikawa, E; Matsumura, A; Morishita, Y; Nakai, K; Ohno, T; Sakamoto, N; Sato, M; Satomi, K; Takano, S; Tsuboi, K; Yamamoto, T, 2011)
"This study was designed to evaluate proton magnetic resonance spectroscopy ((1)H-MRS) for monitoring the WHO grade II glioma (low-grade glioma (LGG)) treated with temozolomide (TMZ)."7.77Predicting the outcome of grade II glioma treated with temozolomide using proton magnetic resonance spectroscopy. ( Abud, L; Capelle, L; Chiras, J; Costalat, R; De Marco, G; Guillevin, R; Habas, C; Hoang-Xuan, K; Menuel, C; Taillibert, S; Vallée, JN, 2011)
" In vitro Southern Blot analysis and cytopathic effect assays demonstrate high anti-glioma potency, which was significantly increased in combination with temozolomide (TMZ), daunorubicin and cisplatin."7.77YB-1 dependent virotherapy in combination with temozolomide as a multimodal therapy approach to eradicate malignant glioma. ( Anton, M; Gänsbacher, B; Haczek, C; Holm, PS; Holzmüller, R; Kasajima, A; Lage, H; Mantwill, K; Rognoni, E; Schlegel, J; Schuster, T; Treue, D; Weichert, W, 2011)
"Patients with high-grade gliomas (HGG) routinely receive radiation, temozolomide, and glucocorticoids."7.77Immunosuppression in patients with high-grade gliomas treated with radiation and temozolomide. ( Carraway, H; Desideri, S; Grossman, SA; Lesser, G; Piantadosi, S; Sloan, A; Ye, X, 2011)
"Temozolomide (TMZ) is an alkylating agent that has yielded significant benefits and is a current standard agent in the treatment of malignant gliomas."7.77Gene expression profiles predicting the response to IFN-β and a combination of temozolomide and IFN-β in malignant gliomas. ( Fukushima, T; Katayama, Y; Ogino, A; Ohta, T; Okamoto, Y; Sano, E; Tashiro, S; Tsumoto, K; Watanabe, T; Yachi, K; Yoshino, A, 2011)
"The goal of this study was to evaluate accelerated radiotherapy with and without temozolomide (TMZ) for glioblastoma multiforme (GBM)."7.77Prolonged survival when temozolomide is added to accelerated radiotherapy for glioblastoma multiforme. ( Buttmann, M; Flentje, M; Guckenberger, M; Mayer, M; Sweeney, RA; Vince, GH, 2011)
"A 61-year-old man with glioblastoma and positive for hepatitis B surface antigen (HBsAg) developed acute hepatitis due to hepatitis B virus (HBV) reactivation after concomitant postoperative treatment with temozolomide (75 mg/m(2)/day) and radiation therapy (60 Gy in 30 fractions)."7.77Reactivation of hepatitis B virus after glioblastoma treatment with temozolomide--case report. ( Kayama, T; Miyakita, Y; Narita, Y; Ohno, M; Shibui, S; Ueno, H, 2011)
"The objective of this retrospective analysis was to assess long-term outcome and prognostic factors of unselected patients treated for glioblastoma (GB) at a single center with surgery, standard radiotherapy (RT), and concomitant temozolomide (TMZ)."7.77Radiochemotherapy with temozolomide for patients with glioblastoma. Prognostic factors and long-term outcome of unselected patients from a single institution. ( Franz, K; Gerstein, J; Rödel, C; Seifert, V; Steinbach, JP; Weiss, C, 2011)
"Prolonged administration of temozolomide is widely used in patients with glioblastoma; whereas the treatment of anaplastic glioma differs between neurooncological centres."7.77Prolonged administration of temozolomide in adult patients with anaplastic glioma. ( Freyschlag, CF; Janzen, E; Lohr, F; Schmieder, K; Seiz, M; Smolczyk, DR; Thomé, C; Tuettenberg, J; Weiss, C; Wenz, F, 2011)
"To evaluate the incidence and impact of early post-chemoradiation (cRT) 'pseudoprogression' (PsPD) amongst glioblastoma multiforme (GBM) patients treated with the current standard of care - 60 Gy conformal radiotherapy with concurrent low-dose temozolomide, followed by six cycles of high-dose temozolomide (the 'Stupp protocol')."7.77Early post-treatment pseudo-progression amongst glioblastoma multiforme patients treated with radiotherapy and temozolomide: a retrospective analysis. ( Gunjur, A; Lau, E; Ryan, G; Taouk, Y, 2011)
"To study the efficacy and safety of 3-dimensional conformal radiotherapy combined with temozolomide (TMZ) for gliomas."7.77[Efficacy and safety of 3-dimensional conformal radiotherapy combined with temozolomide for glioma]. ( Tu, Q; Wang, L; Zhou, R; Zhou, W, 2011)
" Recently, the alkylating agent temozolomide, which has demonstrated activity in patients with brain metastasis and primary tumors, was used alongside WBR to delay brain metastasis recurrence, increase survival, and improve quality-of-life in patients with brain metastases."7.77Retrospective study of patients with brain metastases from melanoma receiving concurrent whole-brain radiation and temozolomide. ( Chen, R; Devito, N; Pan, E; Yu, M, 2011)
"The aim of this study was to evaluate cognitive functioning in newly-diagnosed glioblastoma multiforme (GBM) patients during treatment with radiotherapy (RT) plus concomitant and adjuvant temozolomide (TMZ)."7.76Cognitive functioning in glioblastoma patients during radiotherapy and temozolomide treatment: initial findings. ( Bosma, I; Buter, J; Heimans, JJ; Hilverda, K; Klein, M; Peter Vandertop, W; Postma, TJ; Reijneveld, JC; Slotman, BJ, 2010)
"Concomitant daily temozolomide and radiation followed by adjuvant temozolomide is a tolerable and reasonable treatment option and has a good performance status for elderly patients diagnosed with glioblastoma."7.76Concurrent temozolomide and radiation, a reasonable option for elderly patients with glioblastoma multiforme? ( Collichio, F; Ewend, MG; Grabowski, S; Kimple, RJ; Morris, DE; Papez, M, 2010)
"In this study, we investigated the potential of combined treatment with temozolomide (TMZ) chemotherapy and tumor antigen-pulsed dendritic cells (DCs) and the underlying immunological factors of TMZ chemoimmunotherapy with an intracranial GL26 glioma animal model."7.76Immunological factors relating to the antitumor effect of temozolomide chemoimmunotherapy in a murine glioma model. ( Chung, DS; Hong, YK; Kim, CH; Kim, CK; Kim, TG; Park, JS; Park, SD, 2010)
"This study was performed to evaluate the addition of temozolomide (TMZ) to whole brain radiotherapy (WBRT) for brain metastases from melanoma."7.76Brain metastases from melanoma: is there a role for concurrent temozolomide in addition to whole brain radiation therapy? ( Bearden, JD; Behl, D; Brown, PD; Deming, RL; Markovic, SN; Rowland, KM; Sande, JR; Schild, SE, 2010)
"We present two patients with glioblastoma with an unusually stable clinical course and long-term survival who were treated after surgery and radiotherapy with adjuvant temozolomide (TMZ) chemotherapy for 17 and 20 cycles, respectively."7.76Patient-tailored, imaging-guided, long-term temozolomide chemotherapy in patients with glioblastoma. ( Backes, H; Brunn, A; Burghaus, L; Galldiks, N; Heiss, WD; Jacobs, AH; Kracht, LW; Ullrich, RT, 2010)
"O(6)-Methylguanine DNA methyltransferase (MGMT) is implicated as a major predictive factor for treatment response to alkylating agents including temozolomide (TMZ) of glioblastoma multiforme (GBM) patients."7.76O6-Methylguanine DNA methyltransferase protein expression in tumor cells predicts outcome of temozolomide therapy in glioblastoma patients. ( Berger, W; Buchroithner, J; Filipits, M; Fischer, J; Lötsch, D; Micksche, M; Pichler, J; Pirker, C; Silye, R; Spiegl-Kreinecker, S; Weis, S, 2010)
"We hypothesized that the observed clinical synergy of orally administered TMZ and carmustine (BCNU) wafers would translate into even greater effectiveness with the local delivery of BCNU and TMZ and the addition of radiotherapy in animal models of malignant glioma."7.76Combination of intracranial temozolomide with intracranial carmustine improves survival when compared with either treatment alone in a rodent glioma model. ( Bekelis, K; Brem, H; Li, KW; Recinos, VR; Sunshine, SB; Tyler, BM; Vellimana, A, 2010)
"To determine recurrence patterns of glioblastoma treated with temozolomide-based chemoradiation."7.76Patterns and timing of recurrence after temozolomide-based chemoradiation for glioblastoma. ( Donatello, RS; Korones, DN; Milano, MT; Mohile, NA; Okunieff, P; Sul, J; Walter, KA, 2010)
"Novel agents are currently combined with radiation and temozolomide (RT + TMZ) in newly diagnosed glioblastoma using overall survival as the primary end point."7.76Survival of patients with newly diagnosed glioblastoma treated with radiation and temozolomide in research studies in the United States. ( Desideri, S; Fisher, J; Grossman, SA; Nabors, LB; Piantadosi, S; Rosenfeld, M; Ye, X, 2010)
" We present the case of a 26-year-old male suffering a fatal ICH in the context of treatment of a high grade glioma with temozolomide."7.76Intracerebral hemorrhage secondary to thrombocytopenia in a patient treated with temozolomide. ( Anderson, WS; Dunn, I; Norden, A; Sure, D, 2010)
"Concurrent treatment with the methylating agent temozolomide during radiotherapy has yielded the first significant improvement in the survival of adult glioblastomas (GBM) in the last three decades."7.76Minimally cytotoxic doses of temozolomide produce radiosensitization in human glioblastoma cells regardless of MGMT expression. ( Blank, A; Bobola, MS; Kolstoe, DD; Silber, JR, 2010)
"There is a growing evidence of using Temozolomide as upfront therapy for progressive low grade gliomas."7.76Nitrosourea-based chemotherapy for low grade gliomas failing initial treatment with temozolomide. ( Dehais, C; Delattre, JY; Ducray, F; Hoang-Xuan, K; Houillier, C; Idbaih, A; Kaloshi, G; Laigle-Donadey, F; Omuro, A; Psimaras, D; Sanson, M; Sierra del Rio, M; Taillibert, S, 2010)
"To evaluate perfusion parameter changes in patients with glioblastoma multiforme by comparing the perfusion magnetic resonance (MR) imaging measurements obtained before combined radiation and temozolomide therapy (RT-TMZ) with the follow-up MR imaging measurements obtained 1 month after completion of this treatment."7.76Changes in relative cerebral blood volume 1 month after radiation-temozolomide therapy can help predict overall survival in patients with glioblastoma. ( Ekholm, SE; Korones, DN; Mangla, R; Milano, MT; Singh, G; Zhong, J; Ziegelitz, D, 2010)
"Temozolomide is the major drug in the treatment of malignant gliomas."7.76Radiation induced early necrosis in patients with malignant gliomas receiving temozolomide. ( Akmansu, M; Benekli, M; Buyukberber, S; Coskun, U; Kaya, AO; Oner, Y; Ozturk, B; Uncu, D; Yaman, E; Yildiz, R, 2010)
"O(6)-methylguanine-DNA methyltransferase (MGMT) expression in glioblastoma correlates with temozolomide resistance."7.76Effect of alternative temozolomide schedules on glioblastoma O(6)-methylguanine-DNA methyltransferase activity and survival. ( Donze, J; Liu, L; McGraw, M; Palomo, JM; Rahmathulla, G; Robinson, CG; Vogelbaum, MA, 2010)
"The aim of the present study was to investigate the effect of Temozolomide (an alkylating chemotherapeutic agent) and quercetin (natural flavonoid) on cell death in the human astrocytoma cell line MOGGCCM (WHO grade III)."7.76Temozolomide, quercetin and cell death in the MOGGCCM astrocytoma cell line. ( Jakubowicz-Gil, J; Langner, E; Piersiak, T; Rzeski, W; Wertel, I, 2010)
"We present a case of a 12-year-old female with a germline TP53 mutation who presented with anaplastic astrocytoma and subsequent acute lymphoblastic leukemia (ALL) 13 months after starting treatment with temozolomide (TMZ)."7.76Acute lymphoblastic leukemia after temozolomide treatment for anaplastic astrocytoma in a child with a germline TP53 mutation. ( Hosono, A; Makimoto, A; Miyakita, Y; Momota, H; Nariata, Y; Narita, Y; Shibui, S, 2010)
"Standard treatment of glioblastoma multiforme consists of postoperative radiochemotherapy with temozolomide, followed by a 6-month chemotherapy."7.76Aplastic anemia as a cause of death in a patient with glioblastoma multiforme treated with temozolomide. ( Kopecký, J; Kopecký, O; Macingova, Z; Petera, J; Priester, P; Slovácek, L, 2010)
"Malignant glioma patients treated with the golden standard therapy, focal radiotherapy plus concomitant daily temozolomide (radiotherapy/TMZ), often suffer severe lymphopenia."7.76Low peripheral lymphocyte count before focal radiotherapy plus concomitant temozolomide predicts severe lymphopenia during malignant glioma treatment. ( Akutsu, H; Ishikawa, E; Matsumura, A; Nakai, K; Sakamoto, N; Takano, S; Tsuboi, K; Yamamoto, T, 2010)
"Temozolomide (TM) has anti-tumor activity in patients with malignant glioma."7.76Temozolomide/PLGA microparticles plus vatalanib inhibits tumor growth and angiogenesis in an orthotopic glioma model. ( Liu, JM; Tang, GS; Wang, Y; Yue, ZJ; Zhang, H; Zhang, YH, 2010)
"The addition of temozolomide (TMZ) to radiotherapy (RT) improves survival of patients with glioblastoma (GB) when compared to postoperative RT alone in patients up to 65 years of age."7.76Postoperative radiotherapy and concomitant temozolomide for elderly patients with glioblastoma. ( Franz, K; Fraunholz, I; Gerstein, J; Rödel, C; Seifert, V; Steinbach, JP; Weiss, C, 2010)
"To analyze the recurrence patterns in patients with newly diagnosed glioblastoma (GBM) treated with conformal radiotherapy (RT) plus concomitant and adjuvant temozolomide (TMZ), and to compare the patterns of failure according to different target volume delineations."7.76Patterns of failure and comparison of different target volume delineations in patients with glioblastoma treated with conformal radiotherapy plus concomitant and adjuvant temozolomide. ( Amelio, D; Amichetti, M; Arcella, A; Bozzao, A; Enrici, RM; Lanzetta, G; Minniti, G; Muni, R; Salvati, M; Scarpino, S, 2010)
"Temozolomide is an oral alkylating agent approved for the treatment of glioblastoma and anaplastic astrocytoma, and is currently under clinical investigation for the treatment of brain metastases from a variety of cancers."7.76Urticarial hypersensitivity reaction caused by temozolomide. ( Hsu, MY; Ibrahimi, OA; Kesari, S; Pothiawala, S; Yang, C, 2010)
"Some patients with glioblastoma multiform do not respond to temozolomide even though they have aberrant promoter methylation of the DNA repair enzyme O(6)-methylguanine methyltransferase (MGMT)."7.75A MDR1 (ABCB1) gene single nucleotide polymorphism predicts outcome of temozolomide treatment in glioblastoma patients. ( Dill, C; Ehninger, G; Illmer, T; Kestel, L; Kramer, M; Krex, D; Pfirrmann, M; Robel, K; Schackert, G; Schaich, M, 2009)
" In this study, we used pharmacokinetic and pharmacodynamic approaches to investigate how sunitinib at different dose levels affects brain distribution of temozolomide (TMZ), and to ascertain the relationship between intratumoral TMZ concentrations and tumor vascularity in an orthotopic human glioma model."7.75Differential effect of sunitinib on the distribution of temozolomide in an orthotopic glioma model. ( Gallo, JM; Zhou, Q, 2009)
"CpG methylation within the O6-methylguanine-DNA-methyltransferase (MGMT) promoter is associated with enhanced survival of glioblastoma multiforme (GBM) patients treated with temozolomide (TMZ)."7.75Evaluation of MGMT promoter methylation status and correlation with temozolomide response in orthotopic glioblastoma xenograft model. ( Ballman, KV; Buckner, JC; Carlson, BL; Decker, PA; Giannini, C; Grogan, PT; James, CD; Kitange, GJ; Mladek, AC; Sarkaria, JN; Schroeder, MA; Wu, W, 2009)
"We report a case of a 51-year-old woman with newly diagnosed glioblastoma multiforme (GBM) who was treated with surgery followed by the standard concomitant temozolomide (TMZ) and radiotherapy (RT)."7.75Prolonged and severe thrombocytopenia with pancytopenia induced by radiation-combined temozolomide therapy in a patient with newly diagnosed glioblastoma--analysis of O6-methylguanine-DNA methyltransferase status. ( Fujioka, Y; Homori, M; Kurita, H; Miyazaki, H; Nagane, M; Nozue, K; Shimizu, S; Shiokawa, Y; Waha, A, 2009)
"Early radionecrosis after the Stupp protocol is not a rare event due to the radiosensitization effect of temozolomide."7.75Early clinical and neuroradiological worsening after radiotherapy and concomitant temozolomide in patients with glioblastoma: tumour progression or radionecrosis? ( Del Basso De Caro, ML; Elefante, A; Giamundo, A; Maiuri, F; Mariniello, G; Pacelli, R; Peca, C; Vergara, P, 2009)
"The aim of the present study was to evaluate factors predicting the recurrence pattern after the administration of temozolomide (TMZ), initially concurrent with radiotherapy (RT) and subsequently as maintenance therapy, which has become standard treatment for patients with newly diagnosed glioblastoma (GBM)."7.75Recurrence pattern after temozolomide concomitant with and adjuvant to radiotherapy in newly diagnosed patients with glioblastoma: correlation With MGMT promoter methylation status. ( Amistà, P; Brandes, AA; Ermani, M; Franceschi, E; Frezza, G; Morandi, L; Sotti, G; Spagnolli, F; Tosoni, A, 2009)
"Temozolomide (TMZ) is the standard of care for patients with newly diagnosed glioblastoma (GBM) as well as those with recurrent anaplastic glioma (AG) and GBM."7.75Rechallenge with temozolomide in patients with recurrent gliomas. ( Bogdahn, U; Hau, P; Jauch, T; Pascher, C; Weller, M; Wick, A; Wick, W, 2009)
"Temozolomide (TMZ) is an alkylating agent used in the management of gliomas."7.75Long-term use of temozolomide: could you use temozolomide safely for life in gliomas? ( Bell, D; Khasraw, M; Wheeler, H, 2009)
"We have completed in vivo safety and efficacy studies of the use of a novel drug delivery system, a gel matrix-temozolomide formulation that is injected intracranially into the post-resection cavity, as a candidate for glioma therapy."7.75Delivery of temozolomide to the tumor bed via biodegradable gel matrices in a novel model of intracranial glioma with resection. ( Akbar, U; Duntsch, C; Jones, T; Michael, M; Shukla, A; Sun, Y; Winestone, J, 2009)
"Temozolomide is considered the standard of care and drug of choice for the treatment of initially diagnosed malignant gliomas."7.75Glioma-associated endothelial cells are chemoresistant to temozolomide. ( Chen, TC; Golden, EB; Hofman, FM; Pen, L; Schönthal, AH; Sivakumar, W; Virrey, JJ; Wang, W, 2009)
"A 46-year-old man developed Stevens-Johnson syndrome and toxic epidermal necrolysis overlap, with severe localized denudation of the skin on the head and neck, following radiotherapy and oral temozolomide therapy for cranial glioblastoma multiforme."7.75Stevens-Johnson Syndrome and toxic epidermal necrolysis overlap due to oral temozolomide and cranial radiotherapy. ( Sarma, N, 2009)
" On the other hand, temozolomide (TMZ), an oral bioavailable alkylating agent with excellent tolerability, has demonstrated efficacy and has become a key therapeutic agent in patients with malignant gliomas; however, its survival benefit remains unsatisfactory."7.75Effect of IFN-beta on human glioma cell lines with temozolomide resistance. ( Fukushima, T; Katayama, Y; Naruse, N; Ogino, A; Ohta, T; Okamoto, Y; Sano, E; Watanabe, T; Yachi, K; Yoshino, A, 2009)
"A recent randomized study conducted on newly diagnosed glioblastoma (GBM) patients demonstrated that concomitant and adjuvant temozolomide added to standard radiotherapy had a survival advantage compared with radiotherapy alone."7.75Temozolomide concomitant and adjuvant to radiotherapy in elderly patients with glioblastoma: correlation with MGMT promoter methylation status. ( Agati, R; Bacci, A; Benevento, F; Brandes, AA; Calbucci, F; Ermani, M; Franceschi, E; Mazzocchi, V; Scopece, L; Tosoni, A, 2009)
"Previous studies have revealed that p38, a member of the family of stress-activated protein kinases (SAPKs), cooperates with the Chk1-pathway to bring about temozolomide (TMZ)-induced G2 arrest, and that the inhibition of either pathway alone is sufficient to sensitize U87MG glioma cells to TMZ-induced cytotoxicity."7.75Inhibition of c-Jun N-terminal kinase enhances temozolomide-induced cytotoxicity in human glioma cells. ( Hirose, Y; Kawase, T; Ohba, S; Sano, H, 2009)
"Concurrent temozolomide (TMZ) and radiation therapy (RT) followed by adjuvant TMZ is standard treatment for patients with glioblastoma multiforme (GBM), although the relative contribution of concurrent versus adjuvant TMZ is unknown."7.75Radiosensitizing effects of temozolomide observed in vivo only in a subset of O6-methylguanine-DNA methyltransferase methylated glioblastoma multiforme xenografts. ( Ballman, KA; Carlson, BL; Decker, PA; Giannini, C; Grogan, PT; James, CD; Kitange, GJ; Mladek, AC; Sarkaria, JN; Schroeder, MA; Wu, W, 2009)
"Our data suggest that temozolomide is an active regimen for malignant gliomas."7.74Temozolomide in newly diagnosed malignant gliomas: administered concomitantly with radiotherapy, and thereafter as consolidation treatment. ( Akmansu, M; Benekli, M; Buyukberber, S; Coskun, U; Gunel, N; Kaya, AO; Ozkan, S; Ozturk, B; Uner, A; Yamac, D; Yaman, E; Yildiz, R, 2008)
"Although high AGT levels may mediate resistance in a portion of these samples, MMR deficiency does not seem to be responsible for mediating temozolomide resistance in adult malignant glioma."7.74Mismatch repair deficiency does not mediate clinical resistance to temozolomide in malignant glioma. ( Ali-Osman, F; Bigner, DD; Friedman, AH; Friedman, HS; Horne, KS; Johnson, SP; Lister, DW; Maxwell, JA; McLendon, RE; Modrich, PL; Quinn, JA; Rasheed, A, 2008)
" Convection-enhanced delivery (CED) of either the replication-defective, ICP0-producing HSV-1 mutant, d106, or the recombinant d109, devoid of all viral genome expression, was performed to determine the in vivo efficacy of ICP0 in combination with ionizing radiation (IR) or systemic temozolomide (TMZ) in the treatment of glioblastoma multiforme (GBM)."7.74Therapeutic efficacy of a herpes simplex virus with radiation or temozolomide for intracranial glioblastoma after convection-enhanced delivery. ( Deluca, NA; Fellows-Mayle, W; Hadjipanayis, CG, 2008)
"Use of antiangiogenic therapy with radiation and temozolomide in the primary management of high-grade glioma is feasible."7.74Feasibility of using bevacizumab with radiation therapy and temozolomide in newly diagnosed high-grade glioma. ( Eagan, P; Fischer, I; Golfinos, JG; Gruber, ML; Kelly, P; Knopp, EA; Medabalmi, P; Narayana, A; Parker, E; Raza, S; Zagzag, D, 2008)
" In this study, the authors investigate the nature of the SP phenotype in 2 glioma cell lines, U87MG and T98G, and their response to temozolomide."7.74Characterization of a side population of astrocytoma cells in response to temozolomide. ( Ang, BT; Chong, KH; Chua, C; See, SJ; Tang, C; Wong, MC; Zaiden, N, 2008)
"Human GBM-derived cell lines U87, G44, G112, and the gliosarcoma-derived line G28 were treated with EPO, with and without combinations of irradiation or temozolomide (TMZ)."7.74Erythropoietin augments survival of glioma cells after radiation and temozolomide. ( Ehrenreich, H; Giese, A; Hasselblatt, M; Hassouna, I; Jelkmann, W; Kim, E; Rave-Fränk, M; Schulz-Schaeffer, W; Sperling, S, 2008)
"In the 4-year retrospective study, 31 patients with histologically confirmed malignant gliomas, in which 10 patients received radiotherapy followed by temozolomide (group A) and 21 patients received radiotherapy alone (group B)."7.74Radiotherapy followed by adjuvant temozolomide treatment of malignant glioma. ( Chang, HW; Chang, WN; Ho, JT; Lin, WC; Lin, YJ; Lu, CH; Wang, HC; Yang, TM, 2008)
"In this study, we investigated the precursor and active forms of a p53 small-molecule inhibitor for their effects on temozolomide (TMZ) antitumor activity against glioblastoma (GBM), using both in vitro and in vivo experimental approaches."7.74p53 Small-molecule inhibitor enhances temozolomide cytotoxic activity against intracranial glioblastoma xenografts. ( Berger, MS; Dinca, EB; Haas-Kogan, DA; James, CD; Lu, KV; Pieper, RO; Prados, MD; Sarkaria, JN; Vandenberg, SR, 2008)
"Glioblastoma patients undergoing treatment with surgery followed by radiation and temozolomide chemotherapy often develop a state of immunosuppression and are at risk for opportunistic infections and reactivation of hepatitis and herpes viruses."7.74Valproic acid related idiosyncratic drug induced hepatotoxicity in a glioblastoma patient treated with temozolomide. ( Hoorens, A; Neyns, B; Stupp, R, 2008)
" This epigenetic modification has been associated with a favorable prognosis in adult patients with glioblastoma (GBM) who receive temozolomide and other alkylating agents."7.74MGMT promoter methylation correlates with survival benefit and sensitivity to temozolomide in pediatric glioblastoma. ( Addo-Yobo, SO; Donson, AM; Foreman, NK; Gore, L; Handler, MH, 2007)
"Methylating drugs such as temozolomide (TMZ) are widely used in the treatment of brain tumours (malignant gliomas)."7.74Apoptosis in malignant glioma cells triggered by the temozolomide-induced DNA lesion O6-methylguanine. ( Batista, LF; Kaina, B; Menck, CF; Naumann, SC; Roos, WP; Weller, M; Wick, W, 2007)
"Dose-limiting adverse effects of thrombocytopenia and leukopenia prevent augmentation of current temozolomide (TMZ) dosing protocols; therefore, we hypothesized that the direct intracranial delivery of TMZ would lead to improved efficacy in an animal model of malignant glioma in an animal model."7.74Local delivery of temozolomide by biodegradable polymers is superior to oral administration in a rodent glioma model. ( Brem, H; Brem, S; Caplan, J; Legnani, F; Li, K; Pradilla, G; Tyler, B, 2007)
"Following the resection of newly diagnosed or recurrent glioblastomas, local implantation of carmustine-impregnated biodegradable wafers (Gliadel) in the resection cavity constitutes an adjuvant therapy that can improve the possibilities of survival."7.74Fatal outcome related to carmustine implants in glioblastoma multiforme. ( Barcia, JA; Barcia-Mariño, C; Gallego, JM, 2007)
"The aim of this study was to investigate the effect of temozolomide (TZM) in combination with X-rays on proliferation and migration in human glioma spheroids."7.74The inhibition of proliferation and migration of glioma spheroids exposed to temozolomide is less than additive if combined with irradiation. ( Fehlauer, F; Muench, M; Rades, D; Richter, E, 2007)
"Glioblastomas are treated by surgical resection followed by radiotherapy [X-ray therapy (XRT)] and the alkylating chemotherapeutic agent temozolomide."7.74Loss of the mismatch repair protein MSH6 in human glioblastomas is associated with tumor progression during temozolomide treatment. ( Batchelor, TT; Betensky, RA; Cahill, DP; Codd, PJ; Curry, WT; Futreal, PA; Iafrate, AJ; Levine, KK; Louis, DN; Reavie, LB; Romany, CA; Stratton, MR, 2007)
"To evaluate the natural progression and the impact of temozolomide in low-grade gliomas and to correlate these changes with the profile of genetic alterations."7.74Dynamic history of low-grade gliomas before and after temozolomide treatment. ( Amiel-Benouaich, A; Capelle, L; Carpentier, AF; Cornu, P; Delattre, JY; Duffau, H; Guillevin, R; Hoang-Xuan, K; Kaloshi, G; Kujas, M; Laigle-Donadey, F; Lejeune, J; Mandonnet, E; Marie, Y; Mokhtari, K; Omuro, A; Ricard, D; Sanson, M; Taillibert, S, 2007)
"We report the case of a 30-year-old woman with glioblastoma multiforme (GBM) treated with surgery followed by concomitant Temozolomide (TMZ) and external beam radiation, which she tolerated well without any interruptions."7.74Unexpected case of aplastic anemia in a patient with glioblastoma multiforme treated with Temozolomide. ( Gujral, S; Jalali, R; Menon, H; Singh, P, 2007)
"To evaluate the predictive impact of chromosome 1p/19q deletions on the response and outcome of progressive low-grade gliomas (LGG) treated with up-front temozolomide (TMZ) chemotherapy."7.74Temozolomide for low-grade gliomas: predictive impact of 1p/19q loss on response and outcome. ( Benouaich-Amiel, A; Capelle, L; Carpentier, A; Cornu, P; Delattre, JY; Diakite, F; Duffau, H; Hoang-Xuan, K; Idbaih, A; Iraqi, W; Kaloshi, G; Laigle-Donadey, F; Lejeune, J; Mokhtari, K; Omuro, A; Paris, S; Polivka, M; Renard, MA; Sanson, M; Simon, JM; Taillibert, S, 2007)
"The use of adjuvant temozolomide (TMZ) in patients managed with surgery and adjuvant radiation therapy (RT) for glioblastoma multiforme (GBM) has been demonstrated to improve median and 2-year survival in a recent large international multicentre study."7.74Improved median survival for glioblastoma multiforme following introduction of adjuvant temozolomide chemotherapy. ( Ang, EL; Back, MF; Chan, SP; Lim, CC; Ng, WH; See, SJ; Yeo, TT, 2007)
" In this study, as we determined p53 gene mutation occurring in multinucleated giant cell glioblastoma, we investigated the role of Aurora-B in formation of multinucleated cells in human neoplasm cells with various p53 statuses as well as cytotoxity of glioma cells to temozolomide (TMZ), a common oral alkylating agent used in the treatment of gliomas."7.74Inhibition of Aurora-B function increases formation of multinucleated cells in p53 gene deficient cells and enhances anti-tumor effect of temozolomide in human glioma cells. ( Fujita, M; Inagaki, M; Katsumata, S; Mizuno, M; Nakahara, N; Natsume, A; Osawa, H; Satoh, Y; Tsuno, T; Wakabayashi, T; Yoshida, J, 2007)
"Treatment of malignant glioma involves concomitant temozolomide and ionizing radiation (IR)."7.74Adenovirally delivered tumor necrosis factor-alpha improves the antiglioma efficacy of concomitant radiation and temozolomide therapy. ( Bickenbach, K; Galanopoulos, N; Pytel, P; Rawlani, V; Veerapong, J; Weichselbaum, RR; Yamini, B; Yu, X, 2007)
"To investigate the radiosensitizing potential of temozolomide (TMZ) for human glioblastoma multiforme (GBM) cell lines using single-dose and fractionated gamma-irradiation."7.74Differential radiosensitizing potential of temozolomide in MGMT promoter methylated glioblastoma multiforme cell lines. ( Hulsebos, TJ; Lafleur, MV; Leenstra, S; Slotman, BJ; Sminia, P; Stalpers, LJ; van den Berg, J; van Nifterik, KA, 2007)
"To evaluate efficacy and toxicity in elderly patients with glioblastoma multiforme (GBM) treated with postoperative radiochemotherapy with temozolomide (TMZ)."7.74Postoperative treatment of primary glioblastoma multiforme with radiation and concomitant temozolomide in elderly patients. ( Bischof, M; Combs, SE; Debus, J; Schulz-Ertner, D; Wagner, F; Wagner, J; Welzel, T, 2008)
"Diffusion tensor imaging and multiple voxel magnetic resonance spectroscopy were performed in the MRI follow-up of a patient with a glioma treated with temozolomide chemotherapy."7.74Diffusion tensor imaging and chemical shift imaging assessment of heterogeneity in low grade glioma under temozolomide chemotherapy. ( Enting, RH; Heesters, MA; Irwan, R; Meiners, LC; Oudkerk, M; Potze, JH; Sijens, PE; van der Graaf, WT, 2007)
"The purpose of this study was to report our experience with concomitant and adjuvant temozolomide (TMZ) with radiotherapy in patients with newly diagnosed glioblastoma multiforme (GBM)."7.74Encouraging experience of concomitant Temozolomide with radiotherapy followed by adjuvant Temozolomide in newly diagnosed glioblastoma multiforme: single institution experience. ( Basu, A; Goel, A; Gupta, T; Jalali, R; Menon, H; Munshi, A; Sarin, R, 2007)
" Temozolomide is an effective chemotherapeutic agent for patients with glioblastoma multiforme, but it induces significant lymphopenia."7.74Immunological responses in a patient with glioblastoma multiforme treated with sequential courses of temozolomide and immunotherapy: case study. ( Aldape, K; Archer, GE; Bigner, DD; Crutcher, L; Dey, M; Gilbert, M; Hassenbusch, SJ; Heimberger, AB; Hussain, SF; Mitchell, DA; Sampson, JH; Sawaya, R; Schmittling, B; Sun, W, 2008)
"Temozolomide (TMZ), given concurrently with radiotherapy (RT) and as adjuvant monotherapy afterwards, has led to improved survival in glioblastoma multiforme (GBM)."7.74The added value of concurrently administered temozolomide versus adjuvant temozolomide alone in newly diagnosed glioblastoma. ( Avutu, B; Barker, FG; Batchelor, TT; Chakravarti, A; Henson, JW; Hochberg, FH; Loeffler, JS; Martuza, RL; Sher, DJ, 2008)
"32 patients 70 years of age or older with a newly diagnosed glioblastoma and a Karnofsky performance status (KPS) > or = 70 were treated with RT (daily fractions of 2 Gy for a total of 60 Gy) plus temozolomide at the dose of 75 mg/m(2) per day followed by six cycles of adjuvant temozolomide (150-200 mg/m(2) for 5 days during each 28-day cycle)."7.74Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma in elderly patients. ( Bozzao, A; De Paula, U; De Sanctis, V; Filippone, F; Lanzetta, G; Maurizi Enrici, R; Minniti, G; Muni, R; Osti, MF; Tombolini, V; Valeriani, M, 2008)
"To evaluate the feasibility, safety and efficacy of daily temozolomide concurrent with postoperative radiotherapy in malignant glioma."7.73Efficacy and toxicity of postoperative temozolomide radiochemotherapy in malignant glioma. ( Eich, HT; Kocher, M; Kunze, S; Müller, RP; Semrau, R, 2005)
"Patients with glioblastoma containing a methylated MGMT promoter benefited from temozolomide, whereas those who did not have a methylated MGMT promoter did not have such a benefit."7.73MGMT gene silencing and benefit from temozolomide in glioblastoma. ( Bromberg, JE; Cairncross, JG; de Tribolet, N; Diserens, AC; Gorlia, T; Hainfellner, JA; Hamou, MF; Hau, P; Hegi, ME; Janzer, RC; Kros, JM; Mariani, L; Mason, W; Mirimanoff, RO; Stupp, R; Weller, M, 2005)
" This was of interest because E6 silencing of p53 sensitizes U87MG astrocytic glioma cells to BCNU and temozolomide (TMZ), cytotoxic drugs that are modestly helpful in the treatment of aggressive astrocytic gliomas."7.73Pharmaceutical-mediated inactivation of p53 sensitizes U87MG glioma cells to BCNU and temozolomide. ( Cairncross, JG; Mymryk, JS; Xu, GW, 2005)
"The aim of this study was to evaluate the efficacy and safety of carmustine (BCNU) in combination with temozolomide as first-line chemotherapy before and after radiotherapy (RT) in patients with inoperable, newly diagnosed glioblastoma multiforme (GBM)."7.73Temozolomide in combination with BCNU before and after radiotherapy in patients with inoperable newly diagnosed glioblastoma multiforme. ( Barrié, M; Braguer, D; Chinot, O; Couprie, C; Dufour, H; Figarella-Branger, D; Grisoli, F; Hoang-Xuan, K; Martin, PM; Muracciole, X; Peragut, JC, 2005)
"Cimetidine added to temozolomide compared with temozolomide alone induced survival benefits in nude mice with U373 human glioblastoma multiforme (GBM) cells orthotopically xenografted in the brain."7.73Combined cimetidine and temozolomide, compared with temozolomide alone: significant increases in survival in nude mice bearing U373 human glioblastoma multiforme orthotopic xenografts. ( Brotchi, J; Camby, I; Darro, F; Gabius, J; Gaussin, JF; James, S; Kiss, R; Lefranc, F, 2005)
"There are new scientific data concerning the treatment of patients with glioblastoma multiforme with concomitant and adjuvant temozolomide following surgery and radiotherapy."7.73[Temozolomide in patients with a glioblastoma multiforme: new developments]. ( Bromberg, JE; Postma, TJ, 2005)
"To describe the results of the treatment of recurrent glioma with temozolomide."7.73[Favourable result for temozolomide in recurrent high-grade glioma]. ( Enting, RH; Kros, JM; Sillevis Smitt, PA; Taal, W; van den Bent, MJ; van der Rijt, CD; van Heuvel, I, 2005)
"Temozolomide (TMZ) is an oral alkylating agent with demonstrated efficacy as therapy for glioblastoma multiforme (GBM) and anaplastic astrocytoma."7.73Economic evaluation of temozolomide in the treatment of recurrent glioblastoma multiforme. ( Hallinen, T; Kivioja, A; Martikainen, JA; Vihinen, P, 2005)
" Treatment of glioblastoma multiforme by temozolomide is considered as a paradigm."7.73Simulating chemotherapeutic schemes in the individualized treatment context: the paradigm of glioblastoma multiforme treated by temozolomide in vivo. ( Antipas, VP; Stamatakos, GS; Uzunoglu, NK, 2006)
"The chemotherapeutic agent temozolomide (TMZ) and the anti-angiogenic agent thalidomide (THD) have both demonstrated anti-tumor activity in patients with recurrent malignant glioma."7.73Combination treatment with temozolomide and thalidomide inhibits tumor growth and angiogenesis in an orthotopic glioma model. ( Jeon, HJ; Kim, H; Kim, JH; Kim, JS; Kim, JT; Kim, MH; Kim, YJ; Lee, DS; Nam, DH; Park, SY; Shin, T; Son, MJ; Song, HS, 2006)
"The purpose of this study was to determine whether a combination treatment of temozolomide with celecoxib is effective in the rat orthotopic glioma model."7.73Combination celecoxib and temozolomide in C6 rat glioma orthotopic model. ( Groves, MD; Kang, SG; Kim, JS; Nam, DH; Park, K, 2006)
"The aim of this study was to determine the efficacy and tolerability of a biochemotherapy regimen, including low-dose subcutaneous interleukin-2 and temozolomide, in patients with metastatic melanoma."7.73Biochemotherapy with temozolomide, cisplatin, vinblastine, subcutaneous interleukin-2 and interferon-alpha in patients with metastatic melanoma. ( Carrera, C; Castel, T; Conill, C; Gascón, P; González Cao, M; Herrero, J; Malvehy, J; Martí, R; Martín, M; Mellado, B; Puig, S; Sánchez, M, 2006)
"Severe temozolomide-induced immunosuppression, exacerbated by corticosteroids, with profound T-cell lymphocytopenia and simultaneous opportunistic infections with Pneumocystis jiroveci pneumonia, brain abscess with Listeria monocytogenes, and cutaneous Kaposi's sarcoma."7.73Listeria brain abscess, Pneumocystis pneumonia and Kaposi's sarcoma after temozolomide. ( Bally, F; Christen, G; de Ribaupierre, S; Ganière, V; Guillou, L; Pica, A; Stupp, R, 2006)
"To re-evaluate the cost effectiveness and median overall survival (OS) achieved in patients with recurrent malignant gliomas treated with temozolomide in British Columbia, as compared to previous lomustine use in the same patient population based on updated outcomes data."7.73Re-evaluation of the cost effectiveness of temozolomide for malignant gliomas in British Columbia. ( Mabasa, VH; Taylor, SC, 2006)
"Temozolomide (TMZ) is a DNA methylating agent that has shown promising antitumor activity against high grade glioma."7.73Potentiation of antiglioma effect with combined temozolomide and interferon-beta. ( Hong, YK; Joe, YA; Kim, TG; Park, JA, 2006)
"In this IRB-approved retrospective study, we analyzed the efficacy of temozolomide on World Health Organization Grade II and III oligodendrogliomas, as well as mixed oligoastrocytomas, to determine if a correlation exists between the tumors' 1p status and control of growth by this new oral agent."7.72Impact of chromosome 1p status in response of oligodendroglioma to temozolomide: preliminary results. ( Barnett, G; Chahlavi, A; Elson, P; Kanner, A; Peereboom, D; Staugaitis, SM, 2003)
"Temozolomide (TMZ) is a DNA methylating agent that has shown promising antitumor activity in recent clinical trials against high grade gliomas, metastatic melanoma, and brain lymphoma."7.72Systemic administration of GPI 15427, a novel poly(ADP-ribose) polymerase-1 inhibitor, increases the antitumor activity of temozolomide against intracranial melanoma, glioma, lymphoma. ( D'Amati, G; Graziani, G; Kalish, V; Leonetti, C; Portarena, I; Scarsella, M; Tentori, L; Vergati, M; Xu, W; Zhang, J; Zupi, G, 2003)
"The present observation suggests that temozolomide may be an active and well tolerated treatment for malignant melanoma brain metastases."7.72Complete response of multiple melanoma brain metastases after treatment with temozolomide. ( Dvorak, J; Hadzi-Nikolov, D; Melichar, B; Petera, J; Zizka, J, 2004)
"The phase III randomised European Organisation for Research and Treatment of Cancer (EORTC) and National Cancer Institute of Canada Clinical Trail Group (NCIC) Intergroup trial (EORTC 26981/22981; CE3) compares irradiation alone with irradiation plus temozolomide for patients with glioblastoma multiforme (GBM)."7.72Quality assurance of the EORTC 26981/22981; NCIC CE3 intergroup trial on radiotherapy with or without temozolomide for newly-diagnosed glioblastoma multiforme: the individual case review. ( Ataman, F; Fisher, B; Mirimanoff, RO; Poortmans, P; Stupp, R, 2004)
"Using a methylation-specific PCR approach, we assessed the methylation status of the CpG island of MGMT in 92 glioma patients who received temozolomide as first-line chemotherapy or as treatment for relapses."7.72CpG island hypermethylation of the DNA repair enzyme methyltransferase predicts response to temozolomide in primary gliomas. ( Aguirre-Cruz, L; Arribas, L; Balaña, C; Esteller, M; García-Lopez, JL; García-Villanueva, M; Paz, MF; Piquer, J; Pollan, M; Reynes, G; Rojas-Marcos, I; Safont, MJ; Sanchez-Cespedes, M; Yaya-Tur, R, 2004)
"Temozolomide is an oral alkylating agent shown to have modest efficacy in the treatment of glioblastoma multiforme."7.72Transcriptional targeting of adenovirally delivered tumor necrosis factor alpha by temozolomide in experimental glioblastoma. ( Gillespie, GY; Kufe, DW; Weichselbaum, RR; Yamini, B; Yu, X, 2004)
"Temozolomide, an imidazotetrazine prodrug has shown activity in phase II studies in patients with high-grade glioma at first recurrence."7.71Temozolomide as second-line chemotherapy for relapsed gliomas. ( Ashley, S; Brada, M; Dowe, A; Hines, F; Kong, A; Short, SC; Traish, D; Trent, S, 2002)
"Temozolomide (TZM) is a novel methylating agent currently under investigation for treatment of recurrent high-grade gliomas."7.71Poly(ADP-ribose) polymerase inhibitor increases growth inhibition and reduces G(2)/M cell accumulation induced by temozolomide in malignant glioma cells. ( Graziani, G; Navarra, P; Portarena, I; Scerrati, M; Tentori, L; Torino, F, 2002)
" 11 (44%) patients showed cerebral metastases prior to therapy with temozolomide."7.71[Temozolomide as therapeutic option for patients with metastatic melanoma and poor prognosis]. ( Christophers, E; Frick, S; Haacke, TC; Hauschild, A; Lischner, S; Rosien, F; Schäfer, F, 2002)
"A case is reported in which temozolomide, a promising new DNA alkylating agent, was successfully used to treat radiation refractory metastatic brain tumors arising from primary breast cancer."7.71Hemorrhagic cystitis as an unexpected adverse reaction to temozolomide: case report. ( Isaacson, BJ; Islam, R; Ratanawong, C; Tipping, SJ; Zickerman, PM, 2002)
"Temozolomide has an evolving role in the treatment of high grade gliomas."7.71An Australian experience with temozolomide for the treatment of recurrent high grade gliomas. ( Ashley, DL; Cher, L; Harris, MT; Rosenthal, MA, 2001)
"The authors determined the tolerance, response rate, and duration of recurrent anaplastic oligodendroglioma in 30 patients to temozolomide given orally at 150 to 200 mg/m2 on days 1 through 5 in cycles of 28 days."7.71Temozolomide chemotherapy in recurrent oligodendroglioma. ( Brandes, AA; Carpentier, AF; Eskens, FA; Keime-Guibert, F; Kros, JM; Taphoorn, MJ; van den Bent, MJ, 2001)
"Gene therapy for malignant glioma with the herpes simplex virus thymidine kinase/ganciclovir (HSV-tk/GCV) system is already in the stage of clinical trials, but still needs major improvement to achieve greater clinical efficacy."7.71Temozolomide enhances herpes simplex virus thymidine kinase/ganciclovir therapy of malignant glioma. ( Chou, TC; Droege, JW; Fels, C; Kramm, CM; Rainov, NG; Schäfer, C, 2001)
"To investigate the effect of temozolomide, a 3-methyl derivative of mitozolomide in combination with X-rays in human glioma-derived cell lines."7.70Survival of human glioma cells treated with various combination of temozolomide and X-rays. ( Heimans, JJ; Slotman, BJ; van den Berg, J; van der Valk, P; van Rijn, J, 2000)
" Temozolomide is a novel methylating agent with proven efficacy against malignant gliomas (MGs) after systemic administration but with dose-limiting myelotoxicity."7.70Temozolomide delivered by intracerebral microinfusion is safe and efficacious against malignant gliomas in rats. ( Archer, GE; Bigner, DD; Friedman, AH; Friedman, HS; Heimberger, AB; Hulette, C; McLendon, RE; Sampson, JH, 2000)
"Glioblastoma is the most common and most aggressive type of primary brain tumor."7.30Granulocyte-macrophage colony stimulating factor enhances efficacy of nimustine rendezvousing with temozolomide plus irradiation in patients with glioblastoma. ( Bu, XY; Cheng, X; Kong, LF; Luo, JC; Qu, MQ; Wang, YW; Yan, ZY; Yang, DY; Zhao, YW, 2023)
"The majority of metastatic colorectal cancers (mCRC) are mismatch repair (MMR) proficient and unresponsive to immunotherapy, whereas MMR-deficient (MMRd) tumors often respond to immune-checkpoint blockade."7.11Temozolomide Treatment Alters Mismatch Repair and Boosts Mutational Burden in Tumor and Blood of Colorectal Cancer Patients. ( Amatu, A; Barault, L; Bardelli, A; Bartolini, A; Battuello, P; Bonoldi, E; Cassingena, A; Crisafulli, G; Di Nicolantonio, F; Germano, G; Idotta, L; Lazzari, L; Luraghi, P; Macagno, M; Marsoni, S; Mauri, G; Morano, F; Personeni, N; Pessei, V; Pietrantonio, F; Sartore-Bianchi, A; Siena, S; Tosi, F; Valtorta, E; Vitiello, PP; Zampino, MG, 2022)
" Only one possibly treatment-related treatment emergent adverse event (TEAE), Grade 1 gingival swelling, was observed."7.01Safety and tolerability of asunercept plus standard radiotherapy/temozolomide in Asian patients with newly-diagnosed glioblastoma: a phase I study. ( Chen, KT; Hsu, PW; Huang, HL; Jung, SM; Ke, YX; Lin, YJ; Toh, CH; Tsai, HC; Tseng, CK; Wei, KC, 2021)
"Glioblastoma is the most common and lethal brain tumor in adults."7.01Current advances in temozolomide encapsulation for the enhancement of glioblastoma treatment. ( Iturrioz-Rodríguez, N; Matheu, A; Sampron, N, 2023)
"Atorvastatin was not shown to improve PFS-6."7.01Atorvastatin in combination with radiotherapy and temozolomide for glioblastoma: a prospective phase II study. ( Aldanan, S; Alghareeb, WA; Alhussain, H; AlNajjar, FH; Alsaeed, E; Alsharm, AA; Altwairgi, AK; Balbaid, AAO; Orz, Y, 2021)
" Methods This is an open-label, 2-arm Phase 1b/2a study (N = 56) of galunisertib (intermittent dosing: 14 days on/14 days off per cycle of 28 days) in combination with TMZ/RTX (n = 40), versus a control arm (TMZ/RTX, n = 16)."6.94Phase 1b/2a study of galunisertib, a small molecule inhibitor of transforming growth factor-beta receptor I, in combination with standard temozolomide-based radiochemotherapy in patients with newly diagnosed malignant glioma. ( Burkholder, T; Capper, D; Cleverly, AL; Desjardins, A; Estrem, ST; Forsyth, P; Guba, SC; Gueorguieva, I; Lahn, MM; Rodon, J; Suarez, C; Wang, S; Wick, A, 2020)
"Primary end point is freedom from new brain metastases at 1 year."6.94Temozolomide in secondary prevention of HER2-positive breast cancer brain metastases. ( Armstrong, TS; Biassou, N; Brastianos, PK; Burton, E; Carter, S; Gilbert, MR; Gril, B; Houston, N; Lipkowitz, S; Lyden, D; Smart, DD; Steeg, PS; Steinberg, SM; Zimmer, AS, 2020)
" In clinical practice, Chinese doctors often use radiotherapy combined with temozolomide (TMZ) to treat these patients, although large-scale prospective studies are lacking."6.90Radiotherapy versus radiotherapy combined with temozolomide in high-risk low-grade gliomas after surgery: study protocol for a randomized controlled clinical trial. ( Guan, H; He, L; He, Y; Mu, X; Peng, X; Wang, J; Wang, Y, 2019)
" Common adverse events (AEs) were blurred vision (63%), fatigue (38%), and photophobia (35%)."6.90Safety and efficacy of depatuxizumab mafodotin + temozolomide in patients with EGFR-amplified, recurrent glioblastoma: results from an international phase I multicenter trial. ( Ansell, PJ; Bain, E; Butowski, N; Gan, HK; Gomez, E; Holen, KD; Kumthekar, P; Lassman, AB; Lee, HJ; Lwin, Z; Maag, D; Merrell, R; Mikkelsen, T; Nabors, LB; Papadopoulos, KP; Penas-Prado, M; Reardon, DA; Roberts-Rapp, L; Scott, AM; Simes, J; van den Bent, MJ; Walbert, T; Wheeler, H; Xiong, H, 2019)
" The aim of this study was to evaluate the efficacy of moderately hypofractionated simultaneous integrated boost intensity-modulated radiotherapy (SIB-IMRT) combined with temozolomide (TMZ) for the postoperative treatment of GBM."6.90Efficacy of moderately hypofractionated simultaneous integrated boost intensity-modulated radiotherapy combined with temozolomide for the postoperative treatment of glioblastoma multiforme: a single-institution experience. ( Chen, G; Chen, L; Li, G; Li, Q; Luo, W; Lv, S; Zhong, L; Zhou, P, 2019)
"Lapatinib was administered at 2500 mg twice daily for two consecutive days per week on a weekly basis throughout concomitant and adjuvant standard therapy."6.84Report of safety of pulse dosing of lapatinib with temozolomide and radiation therapy for newly-diagnosed glioblastoma in a pilot phase II study. ( Cloughesy, TF; Faiq, N; Green, R; Green, S; Hu, J; Lai, A; Mellinghoff, I; Nghiemphu, PL; Yu, A, 2017)
"Apatinib is a novel, oral, small-molecule tyrosine kinase inhibitor that mainly targets vascular endothelial growth factor receptor-2 (VEGFR-2) to inhibit angiogenesis."6.82Combining apatinib and temozolomide for brainstem glioblastoma: a case report and review of literature. ( Sun, X; Xu, X; Xu, Y; Zhan, W; Zhao, L; Zhu, Y, 2022)
"Glioblastoma is a fatal brain tumor with a bleak prognosis."6.82Glioblastoma and Methionine Addiction. ( Sowers, LC; Sowers, ML, 2022)
"Retreatment with temozolomide (TMZ) is one treatment option."6.80Dendritic cell vaccination combined with temozolomide retreatment: results of a phase I trial in patients with recurrent glioblastoma multiforme. ( Ancelet, LR; Bauer, E; Dzhelali, M; Findlay, MP; Gasser, O; Hamilton, DA; Hermans, IF; Hunn, MK; Mester, B; Sharples, KJ; Wood, CE, 2015)
"Everolimus (70 mg/wk) was started 1 week prior to radiation and TMZ, followed by adjuvant TMZ, and continued until disease progression."6.80A phase II trial of everolimus, temozolomide, and radiotherapy in patients with newly diagnosed glioblastoma: NCCTG N057K. ( Anderson, SK; Brown, PD; Buckner, JC; Flynn, PJ; Galanis, E; Giannini, C; Jaeckle, KA; Kaufmann, TJ; Ligon, KL; Ma, DJ; McGraw, S; Peller, PJ; Sarkaria, JN; Schiff, D; Uhm, JH, 2015)
"Temozolomide was given 150 mg/m(2) days 1-7 and 15-21, every 28 days for 8 cycles."6.80Efficacy and patient-reported outcomes with dose-intense temozolomide in patients with newly diagnosed pure and mixed anaplastic oligodendroglioma: a phase II multicenter study. ( Ahluwalia, MS; Brewer, C; Chamberlain, MC; Dahiya, S; Elson, P; Fisher, PG; Hashemi-Sadraei, N; Newton, HB; Pannullo, S; Peereboom, DM; Prayson, R; Schiff, D; Wood, L; Xie, H, 2015)
"Cilengitide was administered intravenously in combination with daily temozolomide (TMZ) and concomitant radiotherapy (RT; wk 1-6), followed by TMZ maintenance therapy (TMZ/RT→TMZ)."6.80Two cilengitide regimens in combination with standard treatment for patients with newly diagnosed glioblastoma and unmethylated MGMT gene promoter: results of the open-label, controlled, randomized phase II CORE study. ( Ashby, L; Depenni, R; Fink, KL; Grujicic, D; Hegi, ME; Hicking, C; Lhermitte, B; Mazurkiewicz, M; Mikkelsen, T; Nabors, LB; Nam, DH; Perry, JR; Picard, M; Reardon, DA; Salacz, M; Tarnawski, R; Zagonel, V, 2015)
"The upfront approach to treatment of glioblastoma in the unresectable population warrants further investigation in randomized controlled phase III trials."6.78Phase II trial of upfront bevacizumab and temozolomide for unresectable or multifocal glioblastoma. ( Bailey, L; Coan, A; Desjardins, A; Friedman, HS; Herndon, JE; Lipp, ES; Lou, E; Peters, KB; Reardon, DA; Sumrall, AL; Turner, S; Vredenburgh, JJ, 2013)
"Seventy-one eligible patients 70 years of age or older with newly diagnosed GBM and a Karnofsky performance status ≥60 were treated with a short course of RT (40 Gy in 15 fractions over 3 weeks) plus TMZ at the dosage of 75 mg/m(2) per day followed by 12 cycles of adjuvant TMZ (150-200 mg/m(2) for 5 days during each 28-day cycle)."6.77Phase II study of short-course radiotherapy plus concomitant and adjuvant temozolomide in elderly patients with glioblastoma. ( Arcella, A; Caporello, P; De Sanctis, V; Enrici, RM; Giangaspero, F; Lanzetta, G; Minniti, G; Salvati, M; Scaringi, C, 2012)
" In addition, various protracted temozolomide dosing schedules have been evaluated as a strategy to further enhance its anti-tumor activity."6.76Effect of CYP3A-inducing anti-epileptics on sorafenib exposure: results of a phase II study of sorafenib plus daily temozolomide in adults with recurrent glioblastoma. ( Bigner, DD; Desjardins, A; Friedman, AH; Friedman, HS; Gururangan, S; Herndon, JE; Janney, D; Marcello, J; McLendon, RE; Peters, K; Reardon, DA; Sampson, JH; Vredenburgh, JJ, 2011)
"Vatalanib was well tolerated with only 2 DLTs (thrombocytopenia and elevated transaminases)."6.76Phase I trial with biomarker studies of vatalanib (PTK787) in patients with newly diagnosed glioblastoma treated with enzyme inducing anti-epileptic drugs and standard radiation and temozolomide. ( Batchelor, TT; Doyle, CL; Drappatz, J; Duda, DG; Eichler, AF; Gerstner, ER; Jain, RK; Plotkin, SR; Wen, PY; Xu, L, 2011)
" On the basis of promising preclinical data, the safety and tolerability of therapy with the mTOR inhibitor RAD001 in combination with radiation (RT) and temozolomide (TMZ) was evaluated in this Phase I study."6.76North Central Cancer Treatment Group Phase I trial N057K of everolimus (RAD001) and temozolomide in combination with radiation therapy in patients with newly diagnosed glioblastoma multiforme. ( Brown, PD; Buckner, JC; Galanis, E; Giannini, C; Jaeckle, KA; McGraw, S; Peller, PJ; Sarkaria, JN; Uhm, JH; Wu, W, 2011)
" The major differences of our protocol from the other past studies were simultaneous use of both sodium borocapate and boronophenylalanine, and combination with fractionated X-ray irradiation."6.76Phase II clinical study of boron neutron capture therapy combined with X-ray radiotherapy/temozolomide in patients with newly diagnosed glioblastoma multiforme--study design and current status report. ( Hiramatsu, R; Hirota, Y; Kawabata, S; Kirihata, M; Kuroiwa, T; Maruhashi, A; Miyata, S; Miyatake, S; Ono, K; Sakurai, Y; Takekita, Y, 2011)
"Temozolomide has an acceptable tolerance in elderly patients with GBM and KPS less than 70."6.76Temozolomide in elderly patients with newly diagnosed glioblastoma and poor performance status: an ANOCEF phase II trial. ( Barrie, M; Beauchesne, P; Campello, C; Cartalat-Carel, S; Catry-Thomas, I; Chinot, O; Delattre, JY; Ducray, F; Gállego Pérez-Larraya, J; Guillamo, JS; Honnorat, J; Huchet, A; Matta, M; Mokhtari, K; Monjour, A; Taillandier, L; Tanguy, ML, 2011)
"Temozolomide was administered at a dose of 150 mg/m(2) daily for five days for the first 28-day cycle and escalated to 200 mg/m(2), during subsequent cycles."6.76A phase I trial of the farnesyl transferase inhibitor, SCH 66336, with temozolomide for patients with malignant glioma. ( Coan, AD; Desjardins, A; Friedman, AH; Friedman, HS; Herndon, JE; Peters, KB; Reardon, DA; Threatt, S; Vredenburgh, JJ, 2011)
"Glioblastoma is a highly vascularised tumour with a high expression of both vascular endothelial growth factor (VEGF) and VEGFR."6.75EORTC study 26041-22041: phase I/II study on concomitant and adjuvant temozolomide (TMZ) and radiotherapy (RT) with PTK787/ZK222584 (PTK/ZK) in newly diagnosed glioblastoma. ( Brandes, AA; Gorlia, T; Hau, P; Kros, JM; Lacombe, D; Mirimanoff, RO; Stupp, R; Tosoni, A; van den Bent, MJ, 2010)
"The treatment of patients with anaplastic oligodendroglioma (AO) has been significantly impacted by the molecular detection of loss of sequences on chromosomes 1p and 19q."6.74Temozolomide single-agent chemotherapy for newly diagnosed anaplastic oligodendroglioma. ( Anderson, J; Avedissian, R; Croteau, D; Doyle, T; Gutierrez, J; Hasselbach, L; Margolis, J; Mikkelsen, T; Paleologos, N; Schultz, L, 2009)
"Temozolomide treatment did not affect TPM plasma concentrations in chronically treated patients."6.73Temozolomide treatment does not affect topiramate and oxcarbazepine plasma concentrations in chronically treated patients with brain tumor-related epilepsy. ( Albani, F; Baruzzi, A; Contin, M; Dinapoli, L; Fabi, A; Jandolo, B; Maschio, M; Pace, A; Zarabla, A, 2008)
" PCB was administered as an oral dosage of 450 mg on days 1-2 and a total dose of 300 mg on day 3."6.73Salvage chemotherapy with procarbazine and fotemustine combination in the treatment of temozolomide treated recurrent glioblastoma patients. ( Boiardi, A; Botturi, A; Eoli, M; Falcone, C; Filippini, G; Fiumani, A; Gaviani, P; Lamperti, E; Salmaggi, A; Silvani, A, 2008)
" CB related adverse events occurring in more than one patient were fatigue, gait disturbance, nystagmus, and confusion."6.73Convection-enhanced delivery of cintredekin besudotox (interleukin-13-PE38QQR) followed by radiation therapy with and without temozolomide in newly diagnosed malignant gliomas: phase 1 study of final safety results. ( Asher, AL; Chang, SM; Croteau, D; Grahn, AY; Husain, SR; Kunwar, S; Lang, FF; Parker, K; Puri, RK; Sampson, JH; Shaffrey, M; Sherman, JW; Vogelbaum, MA, 2007)
"Perillyl alcohol has shown to have both chemopreventive and chemotherapeutic activities in preclinical studies."6.73Preliminary results from a phase I/II study of perillyl alcohol intranasal administration in adults with recurrent malignant gliomas. ( da Fonseca, CO; Fischer, J; Futuro, D; Gattass, CR; Nagel, J; Quirico-Santos, T; Schwartsmann, G, 2008)
"GBM is the grade IV glioma brain cancer which is life-threatening to many individuals affected by this cancer."6.72Temozolomide nano enabled medicine: promises made by the nanocarriers in glioblastoma therapy. ( Shetty, K; Yadav, KS; Yasaswi, PS, 2021)
"Brain metastases are a common complication in patients suffering from metastatic malignant melanoma."6.72Temozolomide with or without radiotherapy in melanoma with unresectable brain metastases. ( Budach, V; Hofmann, M; Kiecker, F; Schlenger, L; Sterry, W; Trefzer, U; Wurm, R, 2006)
"Decision making at disease progression is critical, and classical T1 and T2 imaging remain the gold standard."6.72Perfusion and diffusion MRI of glioblastoma progression in a four-year prospective temozolomide clinical trial. ( Buff, E; Leimgruber, A; Maeder, PP; Meuli, RA; Ostermann, S; Stupp, R; Yeon, EJ, 2006)
"Temozolomide was in general well tolerated; the most frequent side-effects were hematological."6.71Second-line chemotherapy with temozolomide in recurrent oligodendroglioma after PCV (procarbazine, lomustine and vincristine) chemotherapy: EORTC Brain Tumor Group phase II study 26972. ( Baron, B; Boogerd, W; Bravo Marques, J; Chinot, O; De Beule, N; Kros, JM; Taphoorn, MJ; van den Bent, MJ; van der Rijt, CC; Vecht, CJ, 2003)
"Temozolomide is an oral chemotherapeutic agent with efficacy against malignant gliomas and a favorable safety profile."6.71Phase II study of temozolomide without radiotherapy in newly diagnosed glioblastoma multiforme in an elderly populations. ( Barrie, M; Braguer, D; Chinot, OL; Dufour, H; Figarella-Branger, D; Frauger, E; Grisoli, F; Hoang-Xuan, K; Martin, PM; Moktari, K; Palmari, J; Peragut, JC, 2004)
"Temozolomide is a well-tolerated oral alkylating agent with activity in the CNS."6.71Temozolomide for the treatment of brain metastases associated with metastatic melanoma: a phase II study. ( Agarwala, SS; Atkins, M; Buzaid, A; Czarnetski, B; Dreno, B; Gore, M; Kirkwood, JM; Rankin, EM; Skarlos, D; Thatcher, N, 2004)
"We conducted a study to determine the dose-limiting toxicity of an extended dosing schedule of temozolomide (TMZ) when used with a fixed dose of BCNU, or 1,3-bis(2-chloroethyl)-1-nitrosourea (carmustine), taking advantage of TMZ's ability to deplete O6-alkylguanine-DNA-alkyltransferase and the synergistic activity of these two agents."6.71Phase 1 study of 28-day, low-dose temozolomide and BCNU in the treatment of malignant gliomas after radiation therapy. ( Abrey, LE; Kleber, M; Malkin, MG; Raizer, JJ, 2004)
"Temozolomide is an oral alkylating agent that can cross the blood-brain barrier and in phase II and III trials, patients with advanced metastatic melanoma achieved overall response rates of 13 to 21%."6.71The effect of temozolomide-based chemotherapy in patients with cerebral metastases from melanoma. ( Bafaloukos, D; Briassoulis, E; Christodoulou, C; Fountzilas, G; Gogas, H; Hatzichristou, H; Kalofonos, HP; Linardou, H; Panagiotou, P; Tsoutsos, D, 2004)
"Temozolomide was administered starting the first day of RT at 150 mg/m(2) daily for 5 days every 4 weeks for the first cycle and escalated to a maximum dose of 200 mg/m(2)."6.71Phase II study of temozolomide and thalidomide with radiation therapy for newly diagnosed glioblastoma multiforme. ( Chang, SM; Lamborn, KR; Larson, D; Malec, M; Nicholas, MK; Page, M; Prados, MD; Rabbitt, J; Sneed, P; Wara, W, 2004)
"Temozolomide was administered orally each therapy day at a dose of 50 mg/m(2)."6.71Temozolomide combined with irradiation as postoperative treatment of primary glioblastoma multiforme. Phase I/II study. ( Combs, SE; Debus, J; Edler, L; Gutwein, S; Schulz-Ertner, D; Thilmann, C; van Kampen, M; Wannenmacher, MM, 2005)
"Temozolomide is an oral alkylating agent that has equivalent activity to dacarbazine, but it has the advantage of CNS penetration."6.71A phase II study of biochemotherapy for advanced melanoma incorporating temozolomide, decrescendo interleukin-2 and GM-CSF. ( Anderson, C; Baron, A; Gibbs, P; Gonzalez, R; Lewis, KD; O'Day, S; Richards, J; Russ, P; Weber, J; Zeng, C, 2005)
"Temozolomide is a new cytotoxic alkylating agent that has recently been approved in Portugal for the treatment of recurrent high-grade glioma."6.70Temozolomide in second-line treatment after prior nitrosurea-based chemotherapy in glioblastoma multiforme: experience from a Portuguese institution. ( Albano, J; Cernuda, M; Garcia, I; Lima, L; Oliveira, C; Portela, I; Teixeira, MM, 2002)
" The absolute bioavailability of TMZ was 0."6.69Pharmacokinetics of temozolomide in association with fotemustine in malignant melanoma and malignant glioma patients: comparison of oral, intravenous, and hepatic intra-arterial administration. ( Bauer, J; Biollaz, J; Buclin, T; Decosterd, LA; Gander, M; Lejeune, F; Leyvraz, S; Marzolini, C; Shen, F, 1998)
"Glioblastoma (GBM), the most common primary brain tumor, is the most aggressive human cancers, with a median survival rate of only 14."6.61Aberrant Transcriptional Regulation of Super-enhancers by RET Finger Protein-histone Deacetylase 1 Complex in Glioblastoma: Chemoresistance to Temozolomide. ( Aoki, K; Hirano, M; Natsume, A; Ranjit, M; Wakabayashi, T, 2019)
"Temozolomide may cause thrombocytopenia or neutropenia in 3-4% of glioblastoma patients, respectively."6.55MGMT gene variants, temozolomide myelotoxicity and glioma risk. A concise literature survey including an illustrative case. ( Altinoz, MA; Bolukbasi, FH; Ekmekci, CG; Elmaci, I; Sari, R; Sav, A; Yenmis, G, 2017)
"The standard treatment for brain metastases is radiotherapy."6.55Combined treatment for non-small cell lung cancer and breast cancer patients with brain metastases with whole brain radiotherapy and temozolomide: a systematic review and meta-analysis. ( Luo, Y; Tang, J; Tian, J; Xiang, J, 2017)
"Fibrosarcoma is a rare brain tumour with 33 cases reported so far."6.53Intracranial fibrosarcoma treated with adjuvant radiation and temozolomide: Report of a case and review of all published cases. ( Giridhar, P; Gupta, S; Haresh, KP; Julka, PK; Mallick, S; Rath, GK, 2016)
"Glioblastoma is a unique model of non-metastasising disease that kills the vast majority of patients through local growth, despite surgery and local irradiation."6.53Therapeutic interactions of autophagy with radiation and temozolomide in glioblastoma: evidence and issues to resolve. ( Giatromanolaki, A; Koukourakis, MI; Mitrakas, AG, 2016)
"Many physicians are reluctant to treat elderly glioblastoma (GBM) patients as aggressively as younger patients, which is not evidence based due to the absence of validated data from primary studies."6.49Radiotherapy plus concurrent or sequential temozolomide for glioblastoma in the elderly: a meta-analysis. ( Cheng, JX; Dong, Y; Han, N; Liu, BL; Yin, AA; Zhang, LH; Zhang, X, 2013)
" Hematotoxicity is listed as a frequent adverse drug reaction in the US prescribing information and hepatotoxicity has been reported infrequently in the postmarketing period."6.48Severe sustained cholestatic hepatitis following temozolomide in a patient with glioblastoma multiforme: case study and review of data from the FDA adverse event reporting system. ( Bronder, E; Garbe, E; Herbst, H; Kauffmann, W; Klimpel, A; Orzechowski, HD; Sarganas, G; Thomae, M, 2012)
"Glioblastoma is the most frequent primary malignant brain tumor in adults."6.48Integrin inhibitor cilengitide for the treatment of glioblastoma: a brief overview of current clinical results. ( Caporello, P; Enrici, RM; Minniti, G; Scaringi, C, 2012)
"Temozolomide (TMZ) is a DNA-alkylating agent used for the treatment of glioma, astrocytoma, and melanoma."6.47A novel approach to overcome temozolomide resistance in glioma and melanoma: Inactivation of MGMT by gene therapy. ( Jiang, G; Liu, YQ; Pei, DS; Wei, ZP; Xin, Y; Zheng, JN, 2011)
"Temozolomide (TMZ) is an oral alkylating agent with activity in high and LGG."6.47Using different schedules of Temozolomide to treat low grade gliomas: systematic review of their efficacy and toxicity. ( Athanasiou, T; Lashkari, HP; Moreno, L; Saso, S; Zacharoulis, S, 2011)
"Temozolomide (TMZ) is an oral alkylating agent that is regarded as a tolerable and effective drug."6.45Temozolomide in malignant gliomas: current use and future targets. ( Bressler, LR; Seery, TE; Villano, JL, 2009)
" Several preliminary studies have been initiated to address the issue of resistance and suppression of MGMT activity, and have used alternative temozolomide dosing schedules and O(6)-guanine mimetic agents as substrates for MGMT."6.44Mechanisms of disease: temozolomide and glioblastoma--look to the future. ( Chamberlain, MC; Mrugala, MM, 2008)
"Temozolomide has proven benefit in grade II/III gliomas progressive following standard therapy and when added to radiation for glioblastoma."6.44Temozolomide and radiation in low-grade and anaplastic gliomas: temoradiation. ( Schiff, D, 2007)
"Temozolomide (TMZ) is an alkylating agent that was approved for anaplastic astrocytoma and glioblastoma."6.43Optimal role of temozolomide in the treatment of malignant gliomas. ( Hegi, ME; Stupp, R; van den Bent, MJ, 2005)
"Irinotecan is a water-soluble derivative of camptothecin, an alkylator originally extracted from the Chinese tree Camptotheca acuminata."6.42The emerging role of irinotecan (CPT-11) in the treatment of malignant glioma in brain tumors. ( Friedman, HS; Houghton, PJ; Keir, ST, 2003)
" The drug is well tolerated with dose limiting myelosuppression and thrombocytopenia occurring in less than 10% of patients at current dosage schedules."6.41The use of temozolomide in recurrent malignant gliomas. ( Gaya, A; Greenstein, A; Rees, J; Stebbing, J, 2002)
"Temozolomide is a novel, oral, second-generation alkylating agent."6.41Temozolomide in early stages of newly diagnosed malignant glioma and neoplastic meningitis. ( Friedman, HS, 2000)
"Temozolomide, a new drug, has shown promise in treating malignant gliomas and other difficult-to-treat tumors."6.41Temozolomide and treatment of malignant glioma. ( Calvert, H; Friedman, HS; Kerby, T, 2000)
"Glioblastoma is the most common primary malignant tumor of the central nervous system."5.91Comparative Study of Extremely Low-Frequency Electromagnetic Field, Radiation, and Temozolomide Administration in Spheroid and Monolayer Forms of the Glioblastoma Cell Line (T98). ( Ahmadi-Zeidabadi, M; Amirinejad, M; Jomehzadeh, A; Khoei, S; Kordestani, Z; Larizadeh, MH; Yahyapour, R, 2023)
"Glioblastoma (GBM) is the most lethal primary brain tumor in adults and harbors a subpopulation of glioma stem cells (GSCs)."5.91EZH2 interacts with HP1BP3 to epigenetically activate WNT7B that promotes temozolomide resistance in glioblastoma. ( Li, M; Tian, W; Wang, B; Wang, Y; Xu, R; Yu, T; Zeng, A; Zhang, J; Zhou, F; Zhou, Z, 2023)
"Gliomas are one of the most common primary malignant tumors of the central nervous system, and have an unfavorable prognosis."5.91Role of COL6A2 in malignant progression and temozolomide resistance of glioma. ( Hong, X; Ouyang, J; Peng, X; Wang, P; Xiao, B; Zhang, J; Zou, J, 2023)
"Glioblastoma (GBM) is the most frequent brain cancer and more lethal than other cancers."5.91Erythrose inhibits the progression to invasiveness and reverts drug resistance of cancer stem cells of glioblastoma. ( Agredano-Moreno, LT; Gallardo-Pérez, JC; Jimenez-García, LF; López-Marure, R; Robledo-Cadena, DX; Sánchez-Lozada, LG; Trejo-Solís, MC, 2023)
" Based on the genetic testing results, almonertinib combined with anlotinib and temozolomide was administered and obtained 12 months of progression-free survival after the diagnosis of recurrence as the fourth-line treatment."5.91Almonertinib Combined with Anlotinib and Temozolomide in a Patient with Recurrent Glioblastoma with EGFR L858R Mutation. ( Dong, S; Hou, Z; Li, S; Luo, N; Tao, R; Wu, H; Zhang, H; Zhang, X; Zhu, D, 2023)
"Temozolomide (TMZ) is a first line agent used in the clinic for glioblastoma and it has been useful in increasing patient survival rates."5.91Efficient delivery of Temozolomide using ultrasmall large-pore silica nanoparticles for glioblastoma. ( Ahmed-Cox, A; Akhter, DT; Cao, Y; Fletcher, NL; Janjua, TI; Kavallaris, M; Moniruzzaman, M; Popat, A; Raza, A; Thurecht, KJ, 2023)
"Glioblastoma is the most common malignant brain tumor in adults."5.91Influence of MMR, MGMT Promotor Methylation and Protein Expression on Overall and Progression-Free Survival in Primary Glioblastoma Patients Treated with Temozolomide. ( Birkl-Toeglhofer, AM; Brawanski, KR; Freyschlag, CF; Haybaeck, J; Hoeftberger, R; Manzl, C; Sprung, S; Ströbel, T; Thomé, C, 2023)
"Temozolomide (TMZ) is a chemotherapy agent used to treat primary central nervous system tumors."5.91Metastatic Melanoma: A Preclinical Model Standardization and Development of a Chitosan-Coated Nanoemulsion Containing Temozolomide to Treat Brain Metastasis. ( Azambuja, JH; Braganhol, E; de Cássia Sant'ana, R; de Souza, PO; Debom, GN; Fachel, FNS; Gelsleichter, NE; Lenz, GS; Michels, LR; Roliano, GG; Teixeira, FC; Teixeira, HF; Visioli, F, 2023)
" In this paper, we present the effects of juglone alone and in combination with temozolomide on glioblastoma cells."5.91Juglone in Combination with Temozolomide Shows a Promising Epigenetic Therapeutic Effect on the Glioblastoma Cell Line. ( Barciszewska, AM; Belter, A; Gawrońska, I; Giel-Pietraszuk, M; Naskręt-Barciszewska, MZ, 2023)
"Glioblastoma is the most aggressive and fatal form of brain cancer."5.91The antagonistic effects of temozolomide and trichostatin a combination on MGMT and DNA mismatch repair pathways in Glioblastoma. ( Castresana, JS; Denizler-Ebiri, FN; Güven, M; Taşpınar, F; Taşpınar, M, 2023)
"New approaches to the treatment of glioblastoma, including immune checkpoint blockade and oncolytic viruses, offer the possibility of improving glioblastoma outcomes and have as such been under intense study."5.91Agent-Based Modelling Reveals the Role of the Tumor Microenvironment on the Short-Term Success of Combination Temozolomide/Immune Checkpoint Blockade to Treat Glioblastoma. ( Craig, M; Fiset, B; Jenner, AL; Karimi, E; Quail, DF; Surendran, A; Walsh, LA, 2023)
" The most common adverse events were leukocytopenia (66."5.91Safety and Efficacy of Anlotinib Hydrochloride Plus Temozolomide in Patients with Recurrent Glioblastoma. ( Bu, L; Cai, J; Chen, Q; Huang, K; Meng, X; Weng, Y; Xu, Q; Zhan, R; Zhang, L; Zheng, X, 2023)
"Neuroblastoma is the most common tumour in children under 1 year old, accounting for 12-15% of childhood cancer deaths."5.91Autophagy Inhibition via Hydroxychloroquine or 3-Methyladenine Enhances Chemotherapy-Induced Apoptosis in Neuro-Blastoma and Glioblastoma. ( Balachandar, A; Bhagirath, E; Pandey, S; Vegh, C; Wear, D, 2023)
"Allopregnanolone (allo) is a physiological regulator of neuronal activity that treats multiple neurological disorders."5.72Allopregnanolone suppresses glioblastoma survival through decreasing DPYSL3 and S100A11 expression. ( Feng, YH; Hsu, SP; Hsu, TI; Kao, TJ; Ko, CY; Lim, SW; Lin, HY; Wang, SA, 2022)
"Glioblastoma multiforme (GBM) is a primary brain tumor with devastating prognosis."5.72Recycling of SLC38A1 to the plasma membrane by DSCR3 promotes acquired temozolomide resistance in glioblastoma. ( Huang, G; Lin, R; Liu, Y; Ni, B; Qi, ST; Song, H; Wang, H; Wang, Z; Xie, S; Xu, Y; Yi, GZ; Zhang, Y, 2022)
" Therefore, localised approaches that treat GB straight into the tumour site provide an alternative to enhance chemotherapy bioavailability and efficacy, reducing systemic toxicity."5.72Nek1-inhibitor and temozolomide-loaded microfibers as a co-therapy strategy for glioblastoma treatment. ( Arantes, PR; Borges, GR; Braganhol, E; Dalanhol, CS; de Barros Dias, MCH; de Oliveira Merib, J; de Souza, PO; Ferro, MB; Henn, JG; Morás, AM; Moura, DJ; Nugent, M; Reinhardt, LS, 2022)
"Temozolomide (TMZ) is a DNA alkylating agent that appears to have a radiosensitizing effect when used in combination with RT and may be worthwhile in meningioma treatment."5.72Concomitant Temozolomide plus radiotherapy for high-grade and recurrent meningioma: a retrospective chart review. ( Belanger, K; Damek, D; Lillehei, KO; Ormond, DR; Ung, TH, 2022)
" Additionally, by lowering the effective dosage of TMZ, the combination liposomes reduced systemic TMZ-induced toxicity, highlighting the preclinical potential of this novel integrative strategy to deliver combination therapies to brain tumors."5.72Targeted liposomes for combined delivery of artesunate and temozolomide to resistant glioblastoma. ( Chai, T; Du, Q; Hanif, S; Ismail, M; Li, Y; Muhammad, P; Shi, B; Yang, W; Zhang, D; Zheng, M, 2022)
"Temozolomide (TMZ) is a widely used chemotherapeutic drug for glioma."5.72FOXM1-mediated NUF2 expression confers temozolomide resistance to human glioma cells by regulating autophagy via the PI3K/AKT/mTOR signaling pathway. ( Guo, L; Wu, Z, 2022)
" Non-ionising electromagnetic fields represent an emerging option given the potential advantages of safety, low toxicity and the possibility to be combined with other therapies."5.72Selective cell cycle arrest in glioblastoma cell lines by quantum molecular resonance alone or in combination with temozolomide. ( Astori, G; Belli, R; Bernardi, M; Bozza, A; Catanzaro, D; Celli, P; Chieregato, K; Menarin, M; Merlo, A; Milani, G; Peroni, D; Pozzato, A; Pozzato, G; Raneri, FA; Ruggeri, M; Volpin, L, 2022)
"Temozolomide (TMZ) is a chemotherapeutic drug for the treatment of GBM."5.72Temozolomide increases heat shock proteins in extracellular vesicles released from glioblastoma cells. ( Adıgüzel, Z; Kıyga, E; Önay Uçar, E, 2022)
"Glioblastoma multiforme is a malignant neoplasia with a median survival of less than two years and without satisfactory therapeutic options."5.72The role of Shikonin in improving 5-aminolevulinic acid-based photodynamic therapy and chemotherapy on glioblastoma stem cells. ( Buchner, A; Lyu, C; Pohla, H; Schrader, I; Sroka, R; Stadlbauer, B; Stepp, H; Werner, M, 2022)
"Temozolomide (TMZ) is a first-line chemotherapeutic agent for glioblastoma, but the emergence of drug resistance limits its anti-tumor activity."5.72GBP3 promotes glioblastoma resistance to temozolomide by enhancing DNA damage repair. ( Chen, CC; Chen, Y; Grigore, FN; Jin, J; Lan, Q; Li, M; Li, S; Ma, J; Wang, J; Wang, Q; Wu, G; Xu, H; Zhu, H, 2022)
"Metformin is a biguanide drug utilized as the first-line medication in treating type 2 diabetes."5.72Exploring the Mechanism of Adjuvant Treatment of Glioblastoma Using Temozolomide and Metformin. ( Chang, PC; Chen, HY; Feng, SW; Huang, SM; Hueng, DY; Li, YF, 2022)
"Gliomas are the most common type of primary brain tumors, with high recurrence rate and mortality."5.72ZNF300 enhances temozolomide resistance in gliomas by regulating lncRNA SNHG12. ( Fu, J; Peng, J; Tu, G, 2022)
"Apatinib is a multitarget tyrosine kinase inhibitor, which has been reported to exhibit broad antitumor profiles."5.72Apatinib and temozolomide in children with recurrent ependymoma: A case report. ( Li, J; Shen, Z; Shi, L; Zhang, N; Zhao, S, 2022)
"Temozolomide (TMZ) is a first-line clinical chemotherapeutic drug."5.72Piperlongumine-inhibited TRIM14 signaling sensitizes glioblastoma cells to temozolomide treatment. ( Chen, KC; Chen, PH; Ho, KH; Kuo, YY; Liu, AJ; Shih, CM, 2022)
"Glioma is a common type of malignant and aggressive tumor in the brain."5.72Elevated GIGYF2 expression suppresses tumor migration and enhances sensitivity to temozolomide in malignant glioma. ( Chen, M; Feng, W; Li, J; Li, M; Li, T; Liu, Y; Xia, X; Yang, W; Yuan, Q; Zhang, S; Zhou, X; Zuo, M, 2022)
"Addition of temozolomide (TMZ) to radiotherapy (RT) improves overall survival (OS) in patients with glioblastoma (GBM), but previous studies suggest that patients with tumors harboring an unmethylated MGMT promoter derive minimal benefit."5.69Radiotherapy combined with nivolumab or temozolomide for newly diagnosed glioblastoma with unmethylated MGMT promoter: An international randomized phase III trial. ( Baehring, J; Bähr, O; Brandes, AA; Butowski, N; Carpentier, AF; Chalamandaris, AG; Cloughesy, T; Di Giacomo, AM; Fu, AZ; Idbaih, A; Khasraw, M; Lassen, U; Lim, M; Liu, Y; Lombardi, G; Mulholland, P; Muragaki, Y; Omuro, A; Potter, V; Qian, X; Reardon, DA; Roth, P; Sepulveda, JM; Sumrall, A; Tabatabai, G; Tatsuoka, K; van den Bent, M; Vauleon, E; Weller, M, 2023)
" Investigation of adjuvant trotabresib + temozolomide and concomitant trotabresib + temozolomide + radiotherapy in patients with newly diagnosed glioblastoma is ongoing (NCT04324840)."5.69Trotabresib, an oral potent bromodomain and extraterminal inhibitor, in patients with high-grade gliomas: A phase I, "window-of-opportunity" study. ( Amoroso, B; Aronchik, I; Chang, H; Filvaroff, E; González León, P; Hanna, B; Manuel Sepúlveda, J; Mendez, C; Moreno, V; Nikolova, Z; Pérez-Núñez, Á; Reardon, DA; Sanchez-Perez, T; Stephens, D; Vogelbaum, MA; Zuraek, M, 2023)
"Despite intensive treatment with surgery, radiation therapy, temozolomide (TMZ) chemotherapy, and tumor-treating fields, mortality of newly diagnosed glioblastoma (nGBM) remains very high."5.69Phase IIa Study of SurVaxM Plus Adjuvant Temozolomide for Newly Diagnosed Glioblastoma. ( Abad, AP; Ahluwalia, MS; Belal, AN; Birkemeier, MT; Casucci, DM; Ciesielski, MJ; Curry, WT; Dharma, SS; Dhawan, A; Fenstermaker, RA; Figel, SA; Hutson, AD; Liu, S; Mechtler, LL; Mogensen, KM; Peereboom, DM; Qiu, J; Reardon, DA; Withers, HG; Wong, ET, 2023)
"In the randomized phase III trial CeTeG/NOA-09, temozolomide (TMZ)/lomustine (CCNU) combination therapy was superior to TMZ in newly diagnosed MGMT methylated glioblastoma, albeit reporting more frequent hematotoxicity."5.69Patterns, predictors and prognostic relevance of high-grade hematotoxicity after temozolomide or temozolomide-lomustine in the CeTeG/NOA-09 trial. ( Brehmer, S; Bullinger, L; Giordano, FA; Glas, M; Goldbrunner, R; Grauer, O; Hau, P; Herrlinger, U; Kowalski, T; Krex, D; Potthoff, AL; Ringel, F; Sabel, M; Schäfer, N; Schaub, C; Schmidt-Graf, F; Schneider, M; Schnell, O; Seidel, C; Steinbach, JP; Tabatabai, G; Tonn, JC; Tzaridis, T; Vajkoczy, P; Vatter, H; Weller, J; Zeiner, PS; Zeyen, T, 2023)
"Preclinical data showed that prophylactic, low-dose temozolomide (TMZ) significantly prevented breast cancer brain metastasis."5.69Phase I Study and Cell-Free DNA Analysis of T-DM1 and Metronomic Temozolomide for Secondary Prevention of HER2-Positive Breast Cancer Brain Metastases. ( Anders, CK; Arisa, O; Armstrong, TS; Brastianos, P; Burton, E; Carter, S; Connolly, RM; Figg, WD; Gilbert, MR; Houston, N; Jenkins, S; Khan, I; Lipkowitz, S; Mendoza, TR; Mozarsky, B; Nousome, D; Peer, CJ; Shah, R; Smart, DD; Smith, KL; Steeg, PS; Steinberg, SM; Tweed, C; Vera, E; Wu, X; Zhang, W; Zimmer, AS, 2023)
"Despite standard treatments including chemoradiotherapy with temozolomide (TMZ) (STUPP protocol), the prognosis of glioblastoma patients remains poor."5.69Phase I/II study testing the combination of AGuIX nanoparticles with radiochemotherapy and concomitant temozolomide in patients with newly diagnosed glioblastoma (NANO-GBM trial protocol). ( Biau, J; Casile, M; De Beaumont, O; Dufort, S; Durando, X; Le Duc, G; Loeffler, M; Molnar, I; Moreau, J; Seddik, K; Thivat, E, 2023)
"This study was aimed at analyzing the efficacy and safety of an injectable form of chlorogenic acid (CGA) in patients with recurrent high-grade glioma after standard of care treatments, through a first-in-human, open-label, dose-escalation phase I trial."5.69Phase I study of chlorogenic acid injection for recurrent high-grade glioma with long-term follow-up. ( Chen, F; Deng, J; Jiang, J; Kang, X; Kang, Z; Li, S; Li, W; Yang, H; Zhang, J, 2023)
"In an international randomised controlled phase II study of temozolomide (TMZ) versus TMZ in combination with bevacizumab (BEV) in locally diagnosed non-1p/19q co-deleted World Health Organization grade 2 or 3 gliomas with a first and contrast-enhancing recurrence after initial radiotherapy, and overall survival at 12 months was not significantly different (61% in the TMZ arm and 55% in the TMZ + BEV arm)."5.69Health-related quality-of-life results from the randomised phase II TAVAREC trial on temozolomide with or without bevacizumab in 1p/19q intact first-recurrence World Health Organization grade 2 and 3 glioma (European Organization for Research and Treatmen ( Bottomley, A; Clement, PM; Coens, C; de Vos, FYF; Ghislain, I; Golfinopoulos, V; Idbaih, A; Klein, M; Lewis, J; Machingura, A; Mulholland, PJ; Reijneveld, JC; Taal, W; Taphoorn, MJB; van den Bent, MJ; Wick, W, 2023)
"Glioma is the most common primary intracranial tumor."5.62FXYD2 mRNA expression represents a new independent factor that affects survival of glioma patients and predicts chemosensitivity of patients to temozolomide. ( Huang, L; Jiang, T; Li, G; Liu, Y; Zhao, Z; Zhou, K, 2021)
"Glioblastoma multiforme is a malignant central nervous system (CNS) disease with dismal prognosis."5.62Notable response of a young adult with recurrent glioblastoma multiforme to vincristine-irinotecan-temozolomide and bevacizumab. ( Fioretzaki, RG; Kosmas, C; Papageorgiou, GI; Tsakatikas, SA, 2021)
"GBM (glioblastoma multiforme) is the most common and aggressive brain tumor."5.62Regorafenib in glioblastoma recurrence: A case report. ( Desideri, I; Detti, B; Ganovelli, M; Greto, D; Livi, L; Lorenzetti, V; Lucidi, S; Maragna, V; Scoccianti, S; Scoccimarro, E; Teriaca, MA, 2021)
"Temozolomide (TMZ) has been widely used as a first-line treatment for GBM."5.62Intranasal Delivery of Temozolomide-Conjugated Gold Nanoparticles Functionalized with Anti-EphA3 for Glioblastoma Targeting. ( Li, N; Li, Y; Lv, Y; Sha, C; Sun, K; Tang, S; Wang, A; Wang, L; Yan, X; Yu, Y, 2021)
"Temozolomide (TMZ) is an effective chemotherapy drug for glioblastoma, but the resistance to TMZ has come to represent a major clinical problem, and its underlying mechanism has yet to be elucidated."5.62Exosomal connexin 43 regulates the resistance of glioma cells to temozolomide. ( Bi, QC; Gan, LJ; Han, XJ; Hong, T; Jiang, LP; Lan, XM; Liu, LH; Tan, RJ; Wei, MJ; Yang, ZJ; Zhang, LL, 2021)
"Glioblastoma is the most malignant brain tumor and presents high resistance to chemotherapy and radiotherapy."5.62APR-246 combined with 3-deazaneplanocin A, panobinostat or temozolomide reduces clonogenicity and induces apoptosis in glioblastoma cells. ( Castresana, JS; De La Rosa, J; Idoate, MA; Meléndez, B; Rey, JA; Urdiciain, A; Zazpe, I; Zelaya, MV, 2021)
"Glioblastoma is the most common primary brain tumor and remains uniformly fatal, highlighting the dire need for developing effective therapeutics."5.62Nanocell-mediated delivery of miR-34a counteracts temozolomide resistance in glioblastoma. ( Boockvar, J; Brahmbhatt, H; Gao, S; Gonzalez, C; Jamil, E; Khan, MB; MacDiarmid, J; Mugridge, N; Ruggieri, R; Sarkaria, JN; Symons, M; Tran, NL, 2021)
"Celecoxib and 2,5-DMC were the most cytotoxic."5.62COXIBs and 2,5-dimethylcelecoxib counteract the hyperactivated Wnt/β-catenin pathway and COX-2/PGE2/EP4 signaling in glioblastoma cells. ( Kleszcz, R; Krajka-Kuźniak, V; Kruhlenia, N; Majchrzak-Celińska, A; Misiorek, JO; Przybyl, L; Rolle, K, 2021)
"Temozolomide (TMZ) is an alkylating agent widely used for glioma treatment."5.62miR-23b-5p promotes the chemosensitivity of temozolomide via negatively regulating TLR4 in glioma. ( Cui, B; Gao, K; Qiao, Y; Wang, T, 2021)
"Temozolomide was labeled with [11C], and serial PET-MRI scans were performed in patients with recurrent GBM treated with bevacizumab and daily temozolomide."5.56Bevacizumab Reduces Permeability and Concurrent Temozolomide Delivery in a Subset of Patients with Recurrent Glioblastoma. ( Batchelor, T; Beers, AL; Catana, C; Chang, K; Dietrich, J; Duda, DG; Emblem, KE; Gerstner, ER; Hooker, JM; Jain, RK; Kalpathy-Cramer, J; Plotkin, SR; Rosen, B; Vakulenko-Lagun, B; Yen, YF, 2020)
"Perampanel (PER) is a noncompetitive α-amino-3-hydroxy-5-methyl-4-isoaxazolepropionate acid receptor antagonist that has recently been approved for treating focal epilepsy as a secondary drug of choice."5.56Experience of Low Dose Perampanel to Add-on in Glioma Patients with Levetiracetam-uncontrollable Epilepsy. ( Chonan, M; Kanamori, M; Nakasato, N; Osawa, SI; Saito, R; Suzuki, H; Tominaga, T; Watanabe, M, 2020)
" Because the free drug cannot pass the blood-brain barrier (BBB), we investigated the use of nanocarriers for transport of the drug through the BBB and its efficacy when combined with radiotherapy and temozolomide (TMZ) in glioma spheroids."5.56Preclinical evaluation of binimetinib (MEK162) delivered via polymeric nanocarriers in combination with radiation and temozolomide in glioma. ( Becerril Aragon, G; Bikhezar, F; de Kruijff, RM; de Vries, HE; Denkova, AG; Gasol Garcia, A; Narayan, RS; Slotman, BJ; Sminia, P; Torrelo Villa, G; van der Meer, AJGM; van der Pol, SMA, 2020)
"Glioblastoma is the most common primary tumor of the central nervous system that develops chemotherapy resistance."5.56Overexpression miR-486-3p Promoted by Allicin Enhances Temozolomide Sensitivity in Glioblastoma Via Targeting MGMT. ( Chen, J; Chen, L; Hao, B; He, M; Li, X; Wang, C; Wu, H; Zhang, G; Zhang, T, 2020)
"Calpeptin could inhibit the effect."5.56Calpain suppresses cell growth and invasion of glioblastoma multiforme by producing the cleavage of filamin A. ( Cai, L; Li, Q; Li, W; Lu, X; Su, Z; Tu, M; Wang, C; Zhu, Z, 2020)
"Temozolomide (TMZ) is an effective drug for prolonging the overall survival time of patients, while drug-resistance is an important clinical problem at present."5.56A steroidal saponin form Paris vietnamensis (Takht.) reverses temozolomide resistance in glioblastoma cells via inducing apoptosis through ROS/PI3K/Akt pathway. ( Fang, F; Ji, Y; Li, H; Lu, Y; Qiu, P; Tang, H; Zhang, S, 2020)
"The prognosis of glioma is generally poor and is the cause of primary malignancy in the brain."5.56MicroRNA-155-3p promotes glioma progression and temozolomide resistance by targeting Six1. ( Chen, G; Chen, Z; Zhao, H, 2020)
"Glioma is a common cancer that affects people worldwide with high morbidity and mortality."5.56miR-149 rs2292832 C allele enhances the cytotoxic effect of temozolomide against glioma cells. ( Guo, J; Ling, G; Liu, Q; Luo, J; Luo, X; Ning, X; Xu, B, 2020)
"In adults, glioma is the most commonly occurring and invasive brain tumour."5.56CDK4/6 inhibition suppresses tumour growth and enhances the effect of temozolomide in glioma cells. ( Cao, Y; Kong, S; Li, X; Qi, Y; Shang, S, 2020)
"Glioblastoma is the most devastating primary brain tumor and effective therapies are not available."5.56CD73 as a target to improve temozolomide chemotherapy effect in glioblastoma preclinical model. ( Azambuja, JH; Battastini, AMO; Beckenkamp, LR; Braganhol, E; de Oliveira, FH; Gelsleichter, NE; Lenz, GS; Michels, LR; Schuh, RS; Stefani, MA; Teixeira, HF; Wink, MR, 2020)
"Osthole was the most effective."5.56Coumarins modulate the anti-glioma properties of temozolomide. ( Bądziul, D; Jakubowicz-Gil, J; Langner, E; Maciejczyk, A; Rzeski, W; Skalicka-Woźniak, K; Sumorek-Wiadro, J; Wertel, I; Zając, A, 2020)
"Glioma is one of the most aggressive forms of brain tumor and is hallmarked by high rate of mortality, metastasis and drug resistance."5.56Downregulation of hsa_circ_0000936 sensitizes resistant glioma cells to temozolomide by sponging miR-1294. ( Feng, H; Hua, L; Huang, L; Zhang, X, 2020)
"Glioma is the most malignant tumour of the human brain still lacking effective treatment modalities."5.56Synthetic Betulin Derivatives Inhibit Growth of Glioma Cells ( Bębenek, E; Boryczka, S; Dmoszyńska-Graniczka, M; Król, SK; Stepulak, A; Sławińska-Brych, A, 2020)
"Glioblastoma is the most frequent aggressive primary brain tumor amongst human adults."5.56Unraveling response to temozolomide in preclinical GL261 glioblastoma with MRI/MRSI using radiomics and signal source extraction. ( Arús, C; Candiota, AP; Julià-Sapé, M; Ledesma-Carbayo, MJ; Núñez, LM; Romero, E; Santos, A; Vellido, A, 2020)
"Metformin has been linked to improve survival of patients with various cancers."5.56Use of metformin and outcome of patients with newly diagnosed glioblastoma: Pooled analysis. ( Chinot, O; Genbrugge, E; Gorlia, T; Hau, P; Nabors, B; Seliger, C; Stupp, R; Weller, M, 2020)
"In a post hoc analysis of the CATNON trial (NCT00626990), we explored whether adding temozolomide to radiotherapy improves outcome in patients with IDH1/2 wildtype (wt) anaplastic astrocytomas with molecular features of glioblastoma [redesignated as glioblastoma, isocitrate dehydrogenase-wildtype (IDH-wt) in the 2021 World Health Organization (WHO) classification of central nervous system tumors]."5.51Temozolomide and Radiotherapy versus Radiotherapy Alone in Patients with Glioblastoma, IDH-wildtype: Post Hoc Analysis of the EORTC Randomized Phase III CATNON Trial. ( Aldape, K; Atmodimedjo, PN; Baumert, BG; Baurain, JF; Brandes, AA; Brouwer, RWW; Cheung, KJ; Chinot, OL; Clement, PM; de Heer, I; Dubbink, HJ; Erridge, SC; French, PJ; Gill, S; Golfinopoulos, V; Gorlia, T; Griffin, M; Hoogstrate, Y; Jenkins, RB; Kros, JM; Mason, WP; McBain, C; Nowak, AK; Rogers, L; Rudà, R; Sanson, M; Taal, W; Tesileanu, CMS; van den Bent, MJ; van IJcken, WFJ; van Linde, ME; Vogelbaum, MA; von Deimling, A; Weller, M; Wesseling, P; Wheeler, H; Wick, W, 2022)
"Temozolomide is applied as the standard chemotherapy agent in patients with glioblastoma (GBM) after surgery."5.51The efficacy of temozolomide combined with levetiracetam for glioblastoma (GBM) after surgery: a study protocol for a double-blinded and randomized controlled trial. ( Cheng, Y; Huang, N; Liu, G; Mao, J; Sun, M; Tao, Y; Wen, R; Xie, Z; Zhang, X; Zhao, G, 2022)
"Nearly all patients with newly diagnosed glioblastoma experience recurrence following standard-of-care radiotherapy (RT) + temozolomide (TMZ)."5.51Phase III trial of chemoradiotherapy with temozolomide plus nivolumab or placebo for newly diagnosed glioblastoma with methylated MGMT promoter. ( Ansstas, G; Baehring, J; De Vos, F; Finocchiaro, G; Honnorat, J; Idbaih, A; Kinoshita, M; Lee, M; Leung, D; Lim, M; Mellinghoff, IK; Omuro, A; Petrecca, K; Raval, RR; Reardon, DA; Roberts, M; Sahebjam, S; Slepetis, R; Steinbach, J; Sumrall, A; Taylor, JW; Warad, D; Weller, M; Wick, A, 2022)
"Current standard of care for glioblastoma (GBM) includes concurrent chemoradiation and maintenance temozolomide (TMZ) with Tumor Treating Fields (TTFields)."5.51Concurrent chemoradiation and Tumor Treating Fields (TTFields, 200 kHz) for patients with newly diagnosed glioblastoma: patterns of progression in a single institution pilot study. ( Ali, AS; Alnahhas, I; Andrews, DW; Judy, KD; Lombardo, J; Martinez, NL; Miller, RC; Niazi, MZ; Shi, W, 2022)
"Fresh suspected glioblastoma tissue was collected during surgery, and patients with pathology-confirmed GBM enrolled before starting concurrent Radiation Therapy and Temozolomide (RT/TMZ) with Intent to Treat (ITT) after recovery from RT/TMZ."5.51Phase 2 study of AV-GBM-1 (a tumor-initiating cell targeted dendritic cell vaccine) in newly diagnosed Glioblastoma patients: safety and efficacy assessment. ( Abedi, M; Aiken, RD; Bota, DA; Bota, PG; Carrillo, JA; Dillman, RO; Duma, CM; Hsieh, C; Hsu, FPK; Keirstead, HS; Kesari, S; Kong, XT; LaRocca, RV; Nistor, GI; Piccioni, DE; Taylor, TH, 2022)
"Palbociclib treatment significantly reduced tumorigenesis in TMZ-R/HMC3 bearing mice and SNHG15 and CDK6 expression was significantly reduced while miR-627-5p level was increased."5.51Modulating lncRNA SNHG15/CDK6/miR-627 circuit by palbociclib, overcomes temozolomide resistance and reduces M2-polarization of glioma associated microglia in glioblastoma multiforme. ( Bao, H; Jin, H; Li, C; Li, Z; Liang, P; Wang, W; Xiong, J; Zhang, J; Zheng, H, 2019)
"Glioma is one of the most lethal malignancies and molecular regulators driving gliomagenesis are incompletely understood."5.51DHFR/TYMS are positive regulators of glioma cell growth and modulate chemo-sensitivity to temozolomide. ( Dai, X; He, Q; Shao, Y; Tan, B; Wang, J; Weng, Q; Yang, B; Zhao, M, 2019)
"Papaverine is a potential anticancer drug in GBM treatment."5.51Anticancer Non-narcotic Opium Alkaloid Papaverine Suppresses Human Glioblastoma Cell Growth. ( Akasaki, Y; Ichimura, K; Inada, M; Sato, A; Shindo, M; Tanuma, SI; Yamamoto, Y, 2019)
"The KNOG-1101 study showed improved 2-year PFS with temozolomide during and after radiotherapy compared to radiotherapy alone for patients with anaplastic gliomas."5.51Influence of Concurrent and Adjuvant Temozolomide on Health-Related Quality of Life of Patients with Grade III Gliomas: A Secondary Analysis of a Randomized Clinical Trial (KNOG-1101 Study). ( Ahn, GS; Chang, JH; Choe, G; Choi, BS; Hong, YK; Hwang, K; Joo, J; Jung, TY; Kang, SG; Kim, CY; Kim, EY; Kim, JH; Kim, SH; Kim, TM; Kim, YJ; Lee, DE; Nam, DH; Park, CK; Yoo, H, 2022)
"Euphol is a tetracyclic triterpene alcohol, and it is the main constituent of the sap of the medicinal plant Euphorbia tirucalli."5.51Euphol, a tetracyclic triterpene, from Euphorbia tirucalli induces autophagy and sensitizes temozolomide cytotoxicity on glioblastoma cells. ( Carloni, AC; Costa, AM; Evangelista, AF; Jones, C; Lima, JP; Martinho, O; Miranda-Gonçalves, V; Pianowski, LF; Reis, RM; Rosa, MN; Silva, VAO; Tansini, A, 2019)
"Malignant gliomas are aggressive primary neoplasms that originate in the glial cells of the brain or the spine with notable resistance to standard treatment options."5.51Resveratrol restores sensitivity of glioma cells to temozolamide through inhibiting the activation of Wnt signaling pathway. ( Bu, XY; Gao, YS; Han, SY; Hu, S; Qu, MQ; Wang, BQ; Wang, JY; Yan, ZY; Yang, B; Yang, HC, 2019)
"Malignant glioma is a lethal brain tumor with a low survival rate and poor prognosis."5.51Carnosic acid potentiates the anticancer effect of temozolomide by inducing apoptosis and autophagy in glioma. ( Lan, Q; Mao, J; Shao, N; Wang, R; Xue, L; Zhi, F, 2019)
"Glioma is the most common brain malignancy."5.51Local delivery of temozolomide via a biologically inert carrier (Temodex) prolongs survival in glioma patients, irrespectively of the methylation status of MGMT. ( Fedulov, A; Karlsson, I; Lokot, I; Pejler, G; Veevnik, D; Yurkshtovich, N; Yurkshtovich, T, 2019)
"Glioma is a primary intracranial malignant tumor with poor prognosis."5.51Development of transferrin-modified poly(lactic-co-glycolic acid) nanoparticles for glioma therapy. ( Liu, G; Mao, J; Meng, X; Yang, Y; Zhao, C, 2019)
"The aim of the present study was to treat glioblastoma cells with a selective HDAC6 inhibitor, tubastatin A, to determine if the malignant phenotype may be reverted."5.51Tubastatin A, an inhibitor of HDAC6, enhances temozolomide‑induced apoptosis and reverses the malignant phenotype of glioblastoma cells. ( Castresana, JS; Erausquin, E; Idoate, MA; Meléndez, B; Rey, JA; Urdiciain, A, 2019)
" Combinatorial therapy of diosgenin and TMZ significantly reduced the dosage regimen of TMZ and also showed affectivity in hitherto TMZ resistant GBM cells."5.51Targeting NFE2L2, a transcription factor upstream of MMP-2: A potential therapeutic strategy for temozolomide resistant glioblastoma. ( Banerjee, I; Banik, P; Bharti, R; Biswas, A; Das, S; Ghosh, SK; Kumar, U; Mandal, M; Nayak, S; Rajesh, Y, 2019)
"Temozolomide treatment inhibited p50 recruitment to its cognate element as a function of Ser329 phosphorylation while concomitantly increasing p53 recruitment."5.51Temozolomide Treatment Induces lncRNA MALAT1 in an NF-κB and p53 Codependent Manner in Glioblastoma. ( Bernal, GM; Cahill, KE; Crawley, CD; Khodarev, NN; Larsen, G; Mansour, NM; Nunez, L; Raleigh, DR; Spretz, R; Szymura, SJ; Uppal, A; Voce, DJ; Weichselbaum, RR; Wu, L; Yamini, B; Zhang, W, 2019)
"Temozolomide (TMZ) is an important agent against GBM."5.51Inhibition of cyclin E1 overcomes temozolomide resistance in glioblastoma by Mcl-1 degradation. ( Chen, Z; Liang, H; Sun, L, 2019)
"Temozolomide (TMZ) has been the first-line chemotherapeutic agent used, although to achieve a satisfactory clinical effect."5.51Synergistic Suppression of Glioblastoma Cell Growth by Combined Application of Temozolomide and Dopamine D2 Receptor Antagonists. ( Gao, L; Huang, X; Jiang, X; Li, J; Liu, X; Liu, Z; Zeng, T, 2019)
"The therapeutic treatment of glioblastoma multiforme (GBM) remains a major challenge."5.51Angiopep-2 Modified Cationic Lipid-Poly-Lactic-Co-Glycolic Acid Delivery Temozolomide and DNA Repair Inhibitor Dbait to Achieve Synergetic Chemo-Radiotherapy Against Glioma. ( Hua, L; Li, S; Liang, J; Liu, H; Xu, Q; Ye, C; Yu, R; Zhao, L, 2019)
"Glioblastoma multiforme is an astrocyte-derived tumour representing the most aggressive primary brain malignancy."5.51Temozolomide-induced aplastic anaemia and incidental low-grade B-cell non-Hodgkin lymphoma in a geriatric patient with glioblastoma multiforme. ( Aleixo, GF; Batalini, F; Drews, R; Kaufmann, MR, 2019)
" Proliferation, cell cycle, and apoptotic assays were performed with ML00253764, whereas the synergism of the simultaneous combination with temozolomide was evaluated by the combination index method."5.48Melanocortin Receptor-4 and Glioblastoma Cells: Effects of the Selective Antagonist ML00253764 Alone and in Combination with Temozolomide In Vitro and In Vivo. ( Bocci, G; Di Desidero, T; Giuliani, D; Guarini, S; Orlandi, P; Ottani, A; Pacini, S; Pardini, C; Pasqualetti, F; Vaglini, F, 2018)
"Radiochemotherapy involving cisplatinum-based polychemotherapy is more toxic than radiotherapy in combination with temozolomide."5.48Concurrent radiotherapy with temozolomide vs. concurrent radiotherapy with a cisplatinum-based polychemotherapy regimen : Acute toxicity in pediatric high-grade glioma patients. ( Bison, B; Bojko, S; Gielen, GH; Hoffmann, M; Kortmann, RD; Kramm, CM; Pietsch, T; Seidel, C; von Bueren, AO; Warmuth-Metz, M, 2018)
"Temozolomide (TMZ) has been considered to be one of the most effective chemotherapeutic agents to prolong the survival of patients with glioblastoma."5.48Differential Characterization of Temozolomide-Resistant Human Glioma Cells. ( Chen, CC; Huang, BR; Lai, SW; Lin, C; Lin, HY; Liu, YS; Lu, DY; Tsai, CF, 2018)
"Glioma is the most common intracranial malignant tumors, accounting for about 40% of intracranial tumors."5.48MiR-634 sensitizes glioma cells to temozolomide by targeting CYR61 through Raf-ERK signaling pathway. ( Jiang, Y; Tan, Z; Zhao, J, 2018)
"Glioblastoma is the most frequent and aggressive form of high-grade malignant glioma."5.48XRCC3 contributes to temozolomide resistance of glioblastoma cells by promoting DNA double-strand break repair. ( Frohnapfel, L; Kaina, B; Quiros, S; Ringel, F; Roos, WP, 2018)
"Glioblastoma is the most common and aggressive primitive brain tumor in adults."5.48Good tolerability of maintenance temozolomide in glioblastoma patients after severe hematological toxicity during concomitant radiotherapy and temozolomide treatment: report of two cases. ( Bellu, L; Bergo, E; Berti, F; Caccese, M; Dal Pos, S; Della Puppa, A; Denaro, L; Gardiman, MP; Lombardi, G; Pambuku, A; Zagonel, V, 2018)
" Our results demonstrate benefit of ddTMZ after previous treatment with standard TMZ dosing with no apparent increase in treatment-related toxicities."5.48Dose-dense temozolomide for recurrent high-grade gliomas: a single-center retrospective study. ( Garcia, CR; Gruber, L; Kumar, SS; Lightner, DD; Morgan, RM; Slone, SA; Villano, JL, 2018)
"Glioblastoma is the most common malignant brain tumor."5.48Nose-to-brain delivery of temozolomide-loaded PLGA nanoparticles functionalized with anti-EPHA3 for glioblastoma targeting. ( Chu, L; Liu, S; Mu, H; Ni, L; Song, Y; Sun, K; Wang, A; Wu, Z; Yan, X; Zhang, C; Zhao, M, 2018)
"Human glioma is the most common type of primary brain tumor."5.48Downregulation of miR-196b Promotes Glioma Cell Sensitivity to Temozolomide Chemotherapy and Radiotherapy. ( Liu, J; Lv, H; Ma, R; Shao, C; Zhang, G; Zheng, G, 2018)
" ATOR showed similar cytotoxic effect as TMZ to glioma cells, and it may be a safer drug, regarding side effect induction, than chemotherapic agents."5.48Atorvastatin Promotes Cytotoxicity and Reduces Migration and Proliferation of Human A172 Glioma Cells. ( Dal-Cim, T; Lopes, FG; Ludka, FK; Nedel, CB; Oliveira, KA; Tasca, CI, 2018)
"Glioblastoma (GBM) is one of the lethal central nervous system tumors."5.48The Effect of Ascorbic Acid over the Etoposide- and Temozolomide-Mediated Cytotoxicity in Glioblastoma Cell Culture: A Molecular Study. ( Ceylan, S; Gokturk, D; Kelebek, H; Yilmaz, DM, 2018)
"Glioma is the most common primary brain tumor and has an undesirable prognosis due to the blood-brain barrier (BBB) and drug resistance."5.46β-Asarone promotes Temozolomide's entry into glioma cells and decreases the expression of P-glycoprotein and MDR1. ( Fang, Y; Luo, L; Ning, B; Wang, N; Zhang, Q, 2017)
"Glioblastomas (GBM) comprise 17% of all primary brain tumors."5.46Dual treatment with shikonin and temozolomide reduces glioblastoma tumor growth, migration and glial-to-mesenchymal transition. ( Balça-Silva, J; do Carmo, A; Dubois, LG; Echevarria-Lima, J; Ferrer, VP; Lopes, MC; Matias, D; Moura-Neto, V; Pontes, B; Rosário, L; Sarmento-Ribeiro, AB, 2017)
"Glioblastoma is one of the most frequent and aggressive brain tumors."5.46MiR-198 enhances temozolomide sensitivity in glioblastoma by targeting MGMT. ( Jin, X; Liu, N; Nie, E; Shi, Z; Wu, W; You, Y; Yu, T; Zhang, J; Zhou, X, 2017)
"Chlorpromazine is a United States Food and Drug Administration-approved phenothiazine widely used as a psychotropic in clinical practice."5.46Repositioning chlorpromazine for treating chemoresistant glioma through the inhibition of cytochrome c oxidase bearing the COX4-1 regulatory subunit. ( Griguer, CE; Langford, C; Oliva, CR; Suto, MJ; Zhang, W, 2017)
"Guanosine (GUO) is an endogenous nucleoside involved in extracellular signaling that presents neuroprotective effects and also shows the effect of inducing differentiation in cancer cells."5.46Guanosine promotes cytotoxicity via adenosine receptors and induces apoptosis in temozolomide-treated A172 glioma cells. ( Dal-Cim, TA; Lopes, FG; Nedel, CB; Oliveira, KA; Tasca, CI, 2017)
"Temozolomide (TMZ) is an alkylating chemotherapeutic agent widely used in anti-glioma treatment."5.46Genomic profiling of long non-coding RNA and mRNA expression associated with acquired temozolomide resistance in glioblastoma cells. ( Fu, Z; Guo, H; Lian, C; Liu, B; Liu, Y; Xu, N; Yang, Z; Zeng, H, 2017)
" In vivo, we implanted the cells orthotopically in nude mice and administered CBL0137 in various dosing regimens to assess brain and tumor accumulation of CBL0137, its effect on tumor cell proliferation and apoptosis, and on survival of mice with and without temozolomide (TMZ)."5.46Anticancer drug candidate CBL0137, which inhibits histone chaperone FACT, is efficacious in preclinical orthotopic models of temozolomide-responsive and -resistant glioblastoma. ( Barone, TA; Burkhart, CA; Gudkov, AV; Gurova, KV; Haderski, G; Plunkett, RJ; Purmal, AA; Safina, A, 2017)
"Temozolomide is a commonly used chemotherapy drug and frequently causes lymphocytopenia."5.46Cutaneous invasive aspergillosis in a patient with glioblastoma receiving long-term temozolomide and corticosteroid therapy. ( Hatakeyama, S; Ikeda, T; Morisawa, Y; Norizuki, M; Okabe, T; Onishi, T; Sasahara, T; Suzuki, J; Toshima, M; Yokota, H, 2017)
"Temozolomide (TMZ) is a novel cytotoxic agent used as first-line chemotherapy for GBM, however, some individual cells can't be isolated for surgical resection and show treatment-resistance, thus inducing poor prognosis."5.46MALAT1 is a prognostic factor in glioblastoma multiforme and induces chemoresistance to temozolomide through suppressing miR-203 and promoting thymidylate synthase expression. ( Chen, C; Chen, W; Ge, XS; He, J; Kong, KK; Li, FC; Li, H; Li, JL; Li, P; Wang, F; Xu, XK, 2017)
"A 43-year-old man with an anaplastic astrocytoma received radiation therapy synchronized with ranimustine and adjuvant TMZ chemotherapy for 15 cycles."5.46A Case of Therapy-Related Acute Myeloid Leukemia Associated with Adjuvant Temozolomide Chemotherapy for Anaplastic Astrocytoma. ( Kosugi, K; Saito, K; Takahashi, W; Tokuda, Y; Tomita, H, 2017)
"Glioblastoma is the deadliest brain tumor in humans."5.43Anti-tumor activities of luteolin and silibinin in glioblastoma cells: overexpression of miR-7-1-3p augmented luteolin and silibinin to inhibit autophagy and induce apoptosis in glioblastoma in vivo. ( Chakrabarti, M; Ray, SK, 2016)
"Valproic acid (VPA) is an anti-epileptic drug with properties of a histone deacetylase inhibitor (HDACi)."5.43Valproic acid, compared to other antiepileptic drugs, is associated with improved overall and progression-free survival in glioblastoma but worse outcome in grade II/III gliomas treated with temozolomide. ( Dietrich, J; Le, A; McDonnell, E; Nahed, BV; Redjal, N; Reinshagen, C; Walcott, BP, 2016)
"There is no standard treatment for glioblastoma with elements of PNET (GBM-PNET)."5.43Craniospinal irradiation with concomitant and adjuvant temozolomide--a feasibility assessment of toxicity in patients with glioblastoma with a PNET component. ( Fersht, N; Mandeville, HC; Mycroft, J; O'Leary, B; Saran, F; Solda, F; Vaidya, S; Zacharoulis, S, 2016)
"Malignant gliomas are among the most frequent and aggressive cerebral tumors, characterized by high proliferative and invasive indexes."5.43KCa3.1 channel inhibition sensitizes malignant gliomas to temozolomide treatment. ( Catalano, M; Chece, G; D'Alessandro, G; Di Angelantonio, S; Esposito, V; Grimaldi, A; Limatola, C; Mainiero, F; Porzia, A; Ragozzino, D; Salvati, M; Santoro, A; Wulff, H, 2016)
" We show that GSI in combination with RT and TMZ attenuates proliferation, decreases 3D spheroid growth and results into a marked reduction in clonogenic survival in primary and established glioma cell lines."5.43NOTCH blockade combined with radiation therapy and temozolomide prolongs survival of orthotopic glioblastoma. ( Barbeau, LM; Chalmers, AJ; Eekers, DB; Granton, PV; Groot, AJ; Habets, R; Iglesias, VS; King, H; Prickaerts, J; Short, SC; Theys, J; van Hoof, SJ; Verhaegen, F; Vooijs, M; Yahyanejad, S, 2016)
"Pituitary adenomas are the commonest intracranial tumor, but metastases are rare (0."5.43Widely metastatic atypical pituitary adenoma with mTOR pathway STK11(F298L) mutation treated with everolimus therapy. ( Arnal, AV; Donovan, LE; Odia, Y; Wang, SH, 2016)
"Glioblastoma multiforme is the most aggressive malignant primary brain tumor in adults."5.43Increased Expression of System xc- in Glioblastoma Confers an Altered Metabolic State and Temozolomide Resistance. ( Aboody, KS; Cassady, K; Cherryholmes, GA; Marinov, GK; Polewski, MD; Reveron-Thornton, RF, 2016)
"Gliomas are the most common primary intracranial malignant tumors in adults."5.43Analysis of expression and prognostic significance of vimentin and the response to temozolomide in glioma patients. ( Cai, J; Han, B; Jiang, C; Lin, L; Meng, X; Ming, J; Sun, B; Wang, G, 2016)
"Temozolomide (TMZ) is an alkylating agent used for the treatment of aggressive forms of brain tumor based on its antitumor actions."5.43Temozolomide inhibits cellular growth and motility via targeting ERK signaling in glioma C6 cells. ( Gao, S; Liang, J; Wang, W; Wang, Y, 2016)
"Patients with grade IV astrocytoma or glioblastoma multiforme (GBM) have a median survival of <12 months, increased to 14."5.43Regression of a glioblastoma multiforme: spontaneous versus a potential antineoplastic effect of dexamethasone and levetiracetam. ( Ajit, NE; Burton, GV; El-Osta, H; Peddi, P, 2016)
"Seizures are a common symptom in patients with low-grade glioma (LGG), negatively influencing quality of life, if uncontrolled."5.42Seizure reduction in a low-grade glioma: more than a beneficial side effect of temozolomide. ( Dirven, L; Heimans, JJ; Koekkoek, JA; Postma, TJ; Reijneveld, JC; Taphoorn, MJ; Vos, MJ, 2015)
"Malignant glioma is a common and lethal primary brain tumor in adults."5.42VAMP8 facilitates cellular proliferation and temozolomide resistance in human glioma cells. ( Chen, H; Chen, J; Chen, Y; Fan, J; Hu, L; Huai, C; Lu, D; Meng, D; Qin, R; Song, X; Sun, R; Wang, D; Wang, H; Wang, J; Wang, S; Xu, T; Yang, J; Yang, S; Yun, D; Zhang, X; Zhao, Y, 2015)
"These results suggest that Liq treatment enhances glioma cell susceptibility to TMZ by inhibiting the PI3K/AKT/mTOR pathway."5.42Estrogen receptor β agonist enhances temozolomide sensitivity of glioma cells by inhibiting PI3K/AKT/mTOR pathway. ( Chen, J; Jing, L; Li, L; Li, S; Ling, Q; Liu, X; Wang, H; Wang, L; Xia, M; Yang, S, 2015)
"Glioblastoma is a devastating primary brain tumor resistant to conventional therapies."5.42Autophagy inhibition improves the efficacy of curcumin/temozolomide combination therapy in glioblastomas. ( Battastini, AM; Bishop, AJR; Braganhol, E; Bristot, IJ; Figueiró, F; Forcelini, CM; Gelain, DP; Klafke, K; Moreira, JCF; Morrone, M; Paludo, FJ; Terra, SR; Zanotto-Filho, A, 2015)
"Glioblastoma is the most frequent primary malignant brain tumor in adults."5.42Combined anti-Galectin-1 and anti-EGFR siRNA-loaded chitosan-lipid nanocapsules decrease temozolomide resistance in glioblastoma: in vivo evaluation. ( Benoit, JP; Danhier, F; Lagarce, F; Lemaire, L; Messaoudi, K, 2015)
" Primary GBM cells were treated with VPA as a monotherapy and in combination with temozolomide and irradiation."5.42The effect of valproic acid in combination with irradiation and temozolomide on primary human glioblastoma cells. ( Cosgrove, L; Day, B; Fay, M; Head, R; Hosein, AN; Lim, YC; Martin, JH; Rose, S; Sminia, P; Stringer, B, 2015)
"Glioblastoma is the most malignant brain tumor, exhibiting remarkable resistance to treatment."5.42A transcriptomic signature mediated by HOXA9 promotes human glioblastoma initiation, aggressiveness and resistance to temozolomide. ( Correia, S; Costa, BM; Costa, S; Gonçalves, CS; Gonçalves, T; Lopes, JM; Oliveira, AI; Pinto, AA; Pinto, L; Pojo, M; Reis, RM; Rocha, M; Rodrigues, AJ; Sousa, N; Xavier-Magalhães, A, 2015)
"Glioblastoma is the most frequent primary malignant brain tumor in adults."5.42Temozolomide-loaded photopolymerizable PEG-DMA-based hydrogel for the treatment of glioblastoma. ( Danhier, F; des Rieux, A; Fourniols, T; Leprince, JG; Préat, V; Randolph, LD; Staub, A; Vanvarenberg, K, 2015)
"Evidence suggests hyperglycemia is associated with worse outcomes in glioblastoma (GB)."5.42Impact of glycemia on survival of glioblastoma patients treated with radiation and temozolomide. ( Chung, C; Kiehl, TR; Laperriere, N; Lovblom, LE; Mason, W; McNamara, MG; Ménard, C; Millar, BA; Perkins, BA; Tieu, MT, 2015)
" Abemaciclib antitumor activity was assessed in subcutaneous and orthotopic glioma models alone and in combination with standard of care temozolomide (TMZ)."5.42Brain Exposure of Two Selective Dual CDK4 and CDK6 Inhibitors and the Antitumor Activity of CDK4 and CDK6 Inhibition in Combination with Temozolomide in an Intracranial Glioblastoma Xenograft. ( Ajamie, RT; De Dios, A; Gelbert, LM; Kulanthaivel, P; Raub, TJ; Sanchez-Martinez, C; Sawada, GA; Shannon, HE; Staton, BA; Wishart, GN, 2015)
"Temozolomide (TMZ) is an oral alkylating chemotherapeutic agent that prolongs the survival of patients with glioblastoma (GBM)."5.42A New Epigenetic Mechanism of Temozolomide Action in Glioma Cells. ( Barciszewska, AM; Gurda, D; Głodowicz, P; Naskręt-Barciszewska, MZ; Nowak, S, 2015)
"Glioma is one of the most common primary tumors of the central nervous system in adults."5.42Interferon-α/β enhances temozolomide activity against MGMT-positive glioma stem-like cells. ( Chen, FR; Chen, YS; Chen, ZP; Guo, CC; Panasci, L; Qiu, ZK; Sai, K; Shen, D; Wang, J; Yang, QY, 2015)
"Gliomas are the most common primary brain tumors."5.42Inhibition of DNA-repair genes Ercc1 and Mgmt enhances temozolomide efficacy in gliomas treatment: a pre-clinical study. ( Berger, FR; Boccard, SG; Geraci, S; Marand, SV; Pelletier, LA; Pycroft, L, 2015)
"Chemotherapy with the oral alkylating agent temozolomide still prevails as a linchpin in the therapeutic regimen of glioblastoma alongside radiotherapy."5.41Temozolomide Resistance: A Multifarious Review on Mechanisms Beyond ( Chamallamudi, MR; Kumar, G; Kumar, N; Nandakumar, K; Rao, V; Thorat, ND; Vibhavari, RJA, 2023)
" Temozolomide (TMZ) has anti-proliferative and cytotoxic effects and is indicated for glioblastoma multiforme and recurrent mesenchymal astrocytoma."5.41Progress in research and development of temozolomide brain-targeted preparations: a review. ( Chen, J; Fan, W; Fu, Z; Wu, X; Xu, Y; Yang, J, 2023)
"Glioblastoma (GBM) remains a fatal diagnosis despite the current standard of care of maximal surgical resection, radiation, and temozolomide (TMZ) therapy."5.41Modeling glioblastoma complexity with organoids for personalized treatments. ( Babak, MV; Balyasnikova, IV; Duffy, JT; Pawlowski, KD, 2023)
"Temozolomide is an oral alkylating agent that is used as the first line treatment for glioblastoma multiform, and in recurrent anaplastic astrocytoma, as well as having demonstrable activity in patients with metastatic melanoma."5.41Is Autophagy Inhibition in Combination with Temozolomide a Therapeutically Viable Strategy? ( Elshazly, AM; Gewirtz, DA, 2023)
"A significant proportion of the human transcriptome, long noncoding RNAs (lncRNAs) play pivotal roles in several aspects of glioblastoma (GBM) pathophysiology including proliferation, invasion, radiation and temozolomide resistance, and immune modulation."5.41The Role of Long Noncoding Ribonucleic Acids in Glioblastoma: What the Neurosurgeon Should Know. ( Chiocca, EA; Villa, GR, 2023)
"Standard treatment for glioblastoma includes maximal safe resection followed by adjuvant radiation and concurrent temozolomide for 6 weeks, followed by 6 months of maintenance temozolomide; additionally, concurrent high doses of corticosteroids are required for many patients to reduce intracranial pressure and reduce inflammatory side effects."5.41Radiotherapy, lymphopenia and improving the outcome for glioblastoma: a narrative review. ( Kleinberg, L; Kut, C, 2023)
"Glioblastoma (GBM) is a highly aggressive and lethal brain tumor with limited treatment options, such as the chemotherapeutic agent, temozolomide (TMZ)."5.41Dysregulated lipid metabolism in TMZ-resistant glioblastoma: pathways, proteins, metabolites and therapeutic opportunities. ( Hsu, TI; Kao, TJ; Li, HY; Lin, CL; Yang, WB, 2023)
"Adults (>18) with newly diagnosed 1p/19q World Health Organization (WHO) grade III oligodendroglioma were randomized to radiotherapy (RT; 5940 centigray ) alone (arm A); RT with concomitant and adjuvant temozolomide (TMZ) (arm B); or TMZ alone (arm C)."5.41CODEL: phase III study of RT, RT + TMZ, or TMZ for newly diagnosed 1p/19q codeleted oligodendroglioma. Analysis from the initial study design. ( Aldape, KD; Anderson, SK; Ballman, KV; Brown, PD; Cairncross, JG; Cerhan, JH; Dhermain, F; Dixon, JG; Flynn, PJ; Galanis, E; Giannini, C; Grossman, SA; Jaeckle, KA; Jenkins, RB; Klein, M; Nordstrom, DG; Raizer, JJ; Schiff, D; van den Bent, M; Vogelbaum, MA; Wefel, JS; Weller, M; Wick, W, 2021)
"Patients age 18 or older with histologically proven and progressive ependymoma or anaplastic ependymoma were eligible and received dose-dense TMZ and daily lapatinib."5.41A phase II study of dose-dense temozolomide and lapatinib for recurrent low-grade and anaplastic supratentorial, infratentorial, and spinal cord ependymoma. ( Aldape, K; Armstrong, TS; Gerstner, ER; Gilbert, MR; Lieberman, F; Mendoza, T; Mikkelsen, T; Omuro, A; Robins, HI; Vera, E; Wen, PY; Wu, J; Yuan, Y, 2021)
" We performed a phase I study to determine the maximum tolerated dose and preliminary efficacy of pegylated nanoliposomal irinotecan (nal-IRI)+metronomic temozolomide (TMZ) in patients with recurrent glioblastoma."5.41Nanoliposomal Irinotecan and Metronomic Temozolomide for Patients With Recurrent Glioblastoma: BrUOG329, A Phase I Brown University Oncology Research Group Trial. ( Baekey, J; Carcieri, A; Cielo, D; Disano, D; Donnelly, J; Elinzano, H; MacKinnon, K; Mohler, A; Robison, J; Safran, H; Sturtevant, A; Toms, S; Vatketich, J; Wood, R, 2021)
"To investigate the toxicity profile and establish an optimal dosing schedule of zotiraciclib with temozolomide in patients with recurrent high-grade astrocytoma."5.41Phase I Study of Zotiraciclib in Combination with Temozolomide for Patients with Recurrent High-grade Astrocytomas. ( Aboud, O; Ahmad, S; Antony, R; Armstrong, TS; Boris, L; Bryla, C; Burton, EM; Butler, MK; Calvo, KR; Cordova, C; Figg, WD; Fink, D; Gallin, JI; Garren, N; Gilbert, MR; Gonzales, J; Grajkowska, E; Kuhns, DB; Leeper, H; Lindsley, M; Lollo, N; Long Priel, DA; Mendoza, TR; Mentges, K; Pang, Y; Peer, CJ; Penas-Prado, M; Siegel, C; Sissung, TM; Su, YT; Theeler, BJ; Vera, E; Wu, J; Yu, G; Yuan, Y, 2021)
"Temozolomide offers minimal benefit in patients with glioblastoma with unmethylated O6-methylguanine-DNA methyltransferase (MGMT) promoter status, hence, the need for novel therapies."5.41A randomized phase II trial of veliparib, radiotherapy, and temozolomide in patients with unmethylated MGMT glioblastoma: the VERTU study. ( Ashley, DM; Back, M; Barnes, EH; Buckland, ME; Fisher, L; Foote, MC; Hall, M; Khasraw, M; Koh, ES; Leonard, R; Lwin, Z; McDonald, KL; Rosenthal, M; Sim, HW; Simes, J; Sulman, EP; Wheeler, H; Yip, S, 2021)
" This preclinical study sought to test the efficacy of the food additive Triacetin (glyceryl triacetate, GTA) as a novel therapy to increase acetate bioavailability in glioma cells."5.40Triacetin-based acetate supplementation as a chemotherapeutic adjuvant therapy in glioma. ( Davies, MT; Driscoll, HE; Jaworski, DM; Lawler, SE; Long, PM; Penar, PL; Pendlebury, WW; Spees, JL; Teasdale, BA; Tsen, AR; Viapiano, MS, 2014)
" We report five patients who received long-term treatment with TMZ chemotherapy at normal dosing levels."5.40Long-term treatment with temozolomide in malignant glioma. ( Defrates, SR; Lightner, DD; Mannas, JP; Pittman, T; Villano, JL, 2014)
"However, TMZ-related acute lymphoblastic leukemia is rare."5.40Temozolomide-related acute lymphoblastic leukemia with translocation (4;11)(q21;q23) in a glioblastoma patient. ( Chang, PY; Chou, KN; Lin, YC; Liu, MY, 2014)
"Glioblastoma is the most common malignant primary brain tumor."5.40EFEMP1 induces γ-secretase/Notch-mediated temozolomide resistance in glioblastoma. ( Boots-Sprenger, SH; Hiddingh, L; Hulleman, E; Jeuken, J; Kaspers, GJ; Noske, DP; Tannous, BA; Teng, J; Tops, B; Vandertop, WP; Wesseling, P; Wurdinger, T, 2014)
"optimal treatment of glioblastoma (gBM) in the elderly remains unclear."5.40Glioblastoma treatment in the elderly in the temozolomide therapy era. ( Al-Zahrani, A; Coate, L; Laperriere, N; Lwin, Z; Macfadden, D; Mason, WP; Massey, C; McNamara, MG; Menard, C; Millar, BA; Sahgal, A, 2014)
"Temozolomide (TMZ) is an alkylating agent used for the treatment of glioblastoma multiforme (GBM), the main form of human brain tumours in adults."5.40Bak and Mcl-1 are essential for Temozolomide induced cell death in human glioma. ( Gratas, C; Oliver, L; Rabé, M; Séry, Q; Vallette, FM, 2014)
"Temozolomide (TMZ) is an oral alkylating agent which is widely used in the treatment of GBM following surgery."5.40miR-128 and miR-149 enhance the chemosensitivity of temozolomide by Rap1B-mediated cytoskeletal remodeling in glioblastoma. ( Cui, Y; Lei, Q; Li, G; She, X; Wang, Z; Wu, M; Xiang, J; Xu, G; Yu, Z, 2014)
"Non-invasive monitoring of response to treatment of glioblastoma (GB) is nowadays carried out using MRI."5.40Molecular imaging coupled to pattern recognition distinguishes response to temozolomide in preclinical glioblastoma. ( Arús, C; Candiota, AP; Delgado-Goñi, T; Julià-Sapé, M; Pumarola, M, 2014)
" In the present work, TMZ was combined with a specific SKI, and the cytotoxic effect of each drug alone or in combination was tested on GBM cell lines."5.40A sphingosine kinase inhibitor combined with temozolomide induces glioblastoma cell death through accumulation of dihydrosphingosine and dihydroceramide, endoplasmic reticulum stress and autophagy. ( Choi, J; Kopp-Schneider, A; Noack, J; Régnier-Vigouroux, A; Richter, K, 2014)
"Malignant glioma is a severe type of brain tumor with a poor prognosis and few options for therapy."5.40Glutathione depletion sensitizes cisplatin- and temozolomide-resistant glioma cells in vitro and in vivo. ( Belizário, JE; de Andrade-Lima, LC; Garcia, CC; Menck, CF; Munford, V; Quinet, A; Rocha, CR; Vieira, DB, 2014)
"Here, we propose a new strategy to treat glioblastoma based on transferrin (Tf)-targeted self-assembled nanoparticles (NPs) incorporating zoledronic acid (ZOL) (NPs-ZOL-Tf)."5.40Medical treatment of orthotopic glioblastoma with transferrin-conjugated nanoparticles encapsulating zoledronic acid. ( Artuso, S; Balestrieri, ML; Caraglia, M; De Rosa, G; Leonetti, C; Luce, A; Lusa, S; Porru, M; Salzano, G; Stoppacciaro, A; Zappavigna, S, 2014)
"Temozolomide was used almost exclusively during CRT (94."5.39Outcomes for patients with anaplastic astrocytoma treated with chemoradiation, radiation therapy alone or radiation therapy followed by chemotherapy: a retrospective review within the era of temozolomide. ( Cahill, D; Gilbert, MR; Lei, X; Shonka, NA; Smith, L; Theeler, B; Yung, A, 2013)
"Glioblastoma multiforme is the most aggressive primary brain tumour."5.39Apoptosis induction in human glioblastoma multiforme T98G cells upon temozolomide and quercetin treatment. ( Bądziul, D; Jakubowicz-Gil, J; Langner, E; Rzeski, W; Wertel, I, 2013)
"C6 rat gliomas were incubated with low-dose TMZ to induce chemoresistance."5.39Trans-1-amino-3-18F-fluorocyclobutanecarboxylic acid (anti-18F-FACBC) is a feasible alternative to 11C-methyl-L-methionine and magnetic resonance imaging for monitoring treatment response in gliomas. ( Baden, A; Doi, Y; Kanagawa, M; Mizoi, K; Oka, S; Ono, T; Sasajima, T; Shimada, N, 2013)
"Temozolomide (TMZ) is an alkylating agent primarily used to treat tumors of the central nervous system."5.39Central diabetes insipidus: a previously unreported side effect of temozolomide. ( Faje, AT; Klibanski, A; Makimura, H; Miller, KK; Nachtigall, L; Wexler, D, 2013)
" In the present analysis, we retrospectively investigated the feasibility and effectiveness of bevacizumab combined with ICE in patients with glioblastoma at second relapse during ICE treatment."5.39Retrospective analysis of bevacizumab in combination with ifosfamide, carboplatin, and etoposide in patients with second recurrence of glioblastoma. ( Arakawa, Y; Fujimoto, K; Kikuchi, T; Kunieda, T; Miyamoto, S; Mizowaki, T; Murata, D; Takagi, Y; Takahashi, JC, 2013)
"Previously, it has been shown that treatment of glioma cells with temozolomide (TMZ) and radiation (XRT) induces the expression of metalloproteinase 14 (MMP14)."5.39Inhibition of MMP14 potentiates the therapeutic effect of temozolomide and radiation in gliomas. ( Auffinger, B; Baryshnikov, AY; Borovjagin, A; Dey, M; Guo, D; Han, Y; Kim, CK; Lesniak, MS; Pytel, P; Sarvaiya, P; Thaci, B; Ulasov, I; Yi, R; Zhang, L, 2013)
"Anaplastic ependymomas are rare tumors in adult patients."5.39Cisplatin and temozolomide combination in the treatment of supratentorial anaplastic ependymoma. ( Bellu, L; Della Puppa, A; Gardiman, MP; Lombardi, G; Pambuku, A; Pomerri, F; Rumanò, L; Zagonel, V, 2013)
"Temozolomide is an attractive candidate treatment in neuroblastoma with methylated MGMT, especially in central nervous system relapsed cases."5.39Efficacy of temozolomide in a central nervous system relapse of neuroblastoma with O 6 -methylguanine methyltransferase (MGMT) promoter methylation. ( Marutsuka, K; Moritake, H; Nunoi, H; Shimonodan, H; Takeshima, H; Yamada, A; Yokogami, K, 2013)
"Gliosarcoma was more common in males (n = 31, 67."5.39Temozolomide use in adult patients with gliosarcoma: an evolving clinical practice. ( Brown, PD; Gilbert, MR; McAleer, MF; Prabhu, SS; Walker, GV, 2013)
"The tumor was partially resected and anaplastic astrocytoma was diagnosed."5.38Hepatitis B virus reactivation associated with temozolomide for malignant glioma: a case report and recommendation for prophylaxis. ( Fujimoto, Y; Hashimoto, N; Kagawa, N; Kinoshita, M; Miyazaki, Y; Takehara, T; Tanaka, S; Yakushijin, T; Yoshimine, T, 2012)
"Primary malignant brain tumors (BT) are the most common and aggressive malignant brain tumor."5.38Intracranial MEMS based temozolomide delivery in a 9L rat gliosarcoma model. ( Bow, H; Brem, H; Cima, MJ; Langer, R; Masi, BC; Tyler, BM; Wicks, RT; Xue, Y, 2012)
" These data reassuringly suggest that BEV does not significantly change the ECF tumor concentrations of TMZ in either tumor-bearing or normal brain when dosed 36 h prior to TMZ."5.38The impact of bevacizumab on temozolomide concentrations in intracranial U87 gliomas. ( Blakeley, JO; Brastianos, H; Brem, H; Grossman, R; Rudek, MA; Tyler, B; Zadnik, P, 2012)
"The management of brain metastases (BM) from breast cancer (BC) needs to be improved, and new therapeutic strategies are urgently requested."5.38Protracted low dose of oral vinorelbine and temozolomide with whole-brain radiotherapy in the treatment for breast cancer patients with brain metastases. ( Addeo, R; Caraglia, M; Carraturo, M; Cennamo, G; Iodice, P; Lombardi, A; Montella, L; Parlato, C; Prete, SD; Russo, P; Salzano, A; Sperlongano, P; Sperlongano, R; Vincenzi, B, 2012)
"These brain tumors are often resistant to chemotherapies like temozolomide (TMZ) and there are very few treatment options available to patients."5.38Disulfiram, a drug widely used to control alcoholism, suppresses the self-renewal of glioblastoma and over-rides resistance to temozolomide. ( Berns, R; Dunn, SE; Fotovati, A; Hu, K; Kast, RE; Kong, E; Lee, C; Luk, M; Pambid, M; Toyota, B; Toyota, E; Triscott, J; Yip, S, 2012)
"All patients had seizure disorders that were treated with anticonvulsants."5.37Impact of temozolomide chemotherapy on seizure frequency in patients with low-grade gliomas. ( Moldovan, K; Pouratian, N; Schiff, D; Shaffrey, ME; Sherman, JH; Starke, RM; Yeoh, HK, 2011)
"Malignant gliomas are highly lethal tumors resistant to current therapies."5.37Lonafarnib (SCH66336) improves the activity of temozolomide and radiation for orthotopic malignant gliomas. ( Barnes, JW; Chaponis, D; Dellagatta, JL; Fast, E; Greene, ER; Kesari, S; Kieran, MW; Kung, AL; Panagrahy, D; Ramakrishna, N; Sauvageot, C; Stiles, C; Wen, PY, 2011)
" We evaluated the preclinical potential of a novel, orally bioavailable PI3K/mTOR dual inhibitor (XL765) in in vitro and in vivo studies."5.37Inhibition of PI3K/mTOR pathways in glioblastoma and implications for combination therapy with temozolomide. ( Aftab, DT; Berger, MS; Haas-Kogan, DA; James, CD; Mueller, S; Ozawa, T; Polley, MY; Prados, MD; Prasad, G; Sottero, T; Weiss, WA; Yang, X, 2011)
"The long-term TMZ-treated astroglioma cells, but not the Hs683 oligodendroglioma cells, developed in vivo a certain level of resistance to TMZ, which correlated with the up- regulation of CXCL2, CXCL3 and CXCL8 expression in the U373 and T98G astroglioma cells."5.37Temozolomide-induced modification of the CXC chemokine network in experimental gliomas. ( Berger, W; Bruyère, C; Kast, RE; Kiss, R; Lefranc, F; Lonez, C; Mijatovic, T; Ruysschaert, JM; Spiegl-Kreinecker, S, 2011)
"The prognostic value of postoperative residual tumor volume in FET PET, TBR(mean,) TBR(max) and Gd-volume was evaluated using Kaplan-Maier estimates for disease-free survival (DFS) and overall survival (OS)."5.37Prognostic impact of postoperative, pre-irradiation (18)F-fluoroethyl-l-tyrosine uptake in glioblastoma patients treated with radiochemotherapy. ( Coenen, HH; Eble, MJ; Galldiks, N; Herzog, H; Holy, R; Kaiser, HJ; Langen, KJ; Pinkawa, M; Piroth, MD; Stoffels, G, 2011)
"Intracranial anaplastic ependymomas are a very rare entity within the group of adult CNS neoplasms."5.37Response to temozolomide in supratentorial multifocal recurrence of malignant ependymoma. ( Freyschlag, CF; Lohr, F; Schmieder, K; Seiz, M; Thomé, C; Tuettenberg, J, 2011)
"Cediranib is a highly potent receptor tyrosine kinase inhibitor that inhibits all three VEGF receptors."5.37Cediranib enhances control of wild type EGFR and EGFRvIII-expressing gliomas through potentiating temozolomide, but not through radiosensitization: implications for the clinic. ( Andersen, B; Dicker, AP; Lawrence, RY; Liu, Y; Wachsberger, PR; Xia, X, 2011)
" The growing body of evidence demonstrating the clinical importance of O6-methylguanine methyltransferase (MGMT) has generated a considerable interest in the exploration of strategies to overcome MGMT-mediated resistance to alkylating agents; for example protracted administration of Temozolomide (TMZ) may result in more extensive and sustained depletion of MGMT; for this reason a variety of dosing schedules that increase the duration of exposure and the cumulative dose of TMZ are being investigated for the treatment of patient with recurrent malignant glioma after standard treatment."5.37Rechallenge with temozolomide in recurrent glioma. ( Botturi, A; Fariselli, L; Ferrari, D; Gaviani, P; Lamperti, E; Salmaggi, A; Silvani, A; Simonetti, G, 2011)
"Gliomas account for more than 50% of all primary brain tumors."5.36Long-term temozolomide treatment induces marked amino metabolism modifications and an increase in TMZ sensitivity in Hs683 oligodendroglioma cells. ( Bontempi, G; Bruyère, C; Decaestecker, C; Dubois, J; Haibe-Kains, B; Kiss, R; Lamoral-Theys, D; Le Calvé, B; Le Mercier, M; Lefranc, F; Rynkowski, MA, 2010)
"Glioblastoma multiforme is the most common and most malignant primary brain tumour."5.36Far-distant metastases along the CSF pathway of glioblastoma multiforme during continuous low-dose chemotherapy with temozolomide and celecoxib. ( Freyschlag, CF; Nölte, I; Pechlivanis, I; Schmieder, K; Seiz, M; Tuettenberg, J; Vajkoczy, P, 2010)
"Temozolomide (TMZ) is a recently introduced alkylating agent that has yielded significant benefits and become a key agent in the treatment of high-grade gliomas."5.36Gene expression profiling predicts response to temozolomide in malignant gliomas. ( Fukushima, T; Katayama, Y; Naruse, N; Ogino, A; Ohta, T; Okamoto, Y; Sano, E; Tsumoto, K; Watanabe, T; Yachi, K; Yoshino, A, 2010)
"High-grade gliomas are among the most lethal of all cancers."5.36Embryonic stem cell (ESC)-mediated transgene delivery induces growth suppression, apoptosis and radiosensitization, and overcomes temozolomide resistance in malignant gliomas. ( Binello, E; Emdad, L; Germano, IM; Qadeer, ZA; Uzzaman, M, 2010)
"Glioblastomas (GBM) are lethal brain tumors that are highly resistant to therapy."5.36PTEN loss compromises homologous recombination repair in astrocytes: implications for glioblastoma therapy with temozolomide or poly(ADP-ribose) polymerase inhibitors. ( Bachoo, RM; Burma, S; Camacho, CV; Hahm, B; McEllin, B; Mukherjee, B; Tomimatsu, N, 2010)
"A 33-year-old woman presented with rare brain metastases from undifferentiated high-grade sarcoma manifesting as headache and vomiting."5.36Brain metastasis of undifferentiated sarcoma and response to temozolomide treatment. Case report. ( Arai, A; Itoh, T; Kanomata, N; Kawamura, A; Kohmura, E; Nishihara, M; Sasayama, T; Tanaka, H, 2010)
"Bortezomib proved to be a more potent inductor of apoptosis than gefitinib and alkylating agents."5.35Cytotoxic and apoptotic effects of bortezomib and gefitinib compared to alkylating agents on human glioblastoma cells. ( Cambar, J; De Giorgi, F; Ichas, F; L'Azou, B; Passagne, I; Pédeboscq, S; Pometan, JP, 2008)
" The system analysis technique, embodied in the convolution integral, generated an impulse response function that, when convolved with temozolomide plasma concentration input functions, yielded predicted normal brain and brain tumor temozolomide concentration profiles for different temozolomide dosing regimens (75-200 mg/m(2)/d)."5.35A new model for prediction of drug distribution in tumor and normal tissues: pharmacokinetics of temozolomide in glioma patients. ( Aboagye, EO; Brock, CS; Gallo, JM; Price, PM; Rosso, L; Saleem, A; Turkheimer, FE, 2009)
"Glioblastoma multiforme is a primary malignant brain tumor with a prognosis of typically less than 2 years."5.35Tonsillary carcinoma after temozolomide treatment for glioblastoma multiforme: treatment-related or dual-pathology? ( Binello, E; Germano, IM, 2009)
"Cilengitide is a cyclic peptide antagonist of integrins alphavbeta3 and alphavbeta5 that is currently being evaluated as a novel therapeutic agent for recurrent and newly diagnosed glioblastoma."5.35Cilengitide modulates attachment and viability of human glioma cells, but not sensitivity to irradiation or temozolomide in vitro. ( Adams, B; Maurer, GD; Stupp, R; Tabatabai, G; Tritschler, I; Weller, M; Wick, W, 2009)
"Carmustine wafer was not an independent predictor (P=."5.35Overall survival of newly diagnosed glioblastoma patients receiving carmustine wafers followed by radiation and concurrent temozolomide plus rotational multiagent chemotherapy. ( Affronti, ML; Bigner, DD; Desjardins, A; Friedman, AH; Friedman, HS; Heery, CR; Herndon, JE; Reardon, DA; Rich, JN; Vredenburgh, JJ, 2009)
" After irradiation of the symptomatic sites, intrathecal liposomal Ara-C every 2-4 weeks was combined with temozolomide 100 mg/m(2) day 1-5/7."5.35Neoplastic meningitis from breast cancer: feasibility and activity of long-term intrathecal liposomal Ara-C combined with dose-dense temozolomide. ( Buhk, JH; Hoffmann, AL; Strik, H, 2009)
" The effect of ZD6474, a potent inhibitor of VEGF-receptor-2, was evaluated in combination with either radiotherapy or temozolomide."5.35Effects of the VEGFR inhibitor ZD6474 in combination with radiotherapy and temozolomide in an orthotopic glioma model. ( Bergenheim, AT; Bergström, P; Henriksson, R; Johansson, M; Sandström, M, 2008)
" Thus, the implantation of BCNU wafers prior to TMZ and radiotherapy appears safe in newly diagnosed GBM patients."5.35A retrospective study of the safety of BCNU wafers with concurrent temozolomide and radiotherapy and adjuvant temozolomide for newly diagnosed glioblastoma patients. ( Mitchell, SB; Pan, E; Tsai, JS, 2008)
"Temozolomide (TMZ) is used for treating glioblastoma."5.35Modulatory effects of acetazolomide and dexamethasone on temozolomide-mediated apoptosis in human glioblastoma T98G and U87MG cells. ( Banik, NL; Das, A; Ray, SK, 2008)
"CINV remains a distressing side effect experienced by glioma patients receiving multi-day temozolomide therapy, in spite of guideline-based antiemetic therapy with selective serotonin-receptor-antagonists."5.34Randomized open-label phase II trial of 5-day aprepitant plus ondansetron compared to ondansetron alone in the prevention of chemotherapy-induced nausea-vomiting (CINV) in glioma patients receiving adjuvant temozolomide. ( Affronti, ML; Desjardins, A; Friedman, HS; Healy, P; Herndon, JE; Lipp, ES; McSherry, F; Miller, E; Patel, MP; Peters, KB; Randazzo, DM; Woodring, S, 2020)
" We investigated Depatux-M in combination with temozolomide or as a single agent in a randomized controlled phase II trial in recurrent EGFR amplified glioblastoma."5.34INTELLANCE 2/EORTC 1410 randomized phase II study of Depatux-M alone and with temozolomide vs temozolomide or lomustine in recurrent EGFR amplified glioblastoma. ( Ansell, P; Brilhante, J; Chinot, O; Clement, PM; Coens, C; De Vos, F; Dey, J; Dubbink, HJ; Eoli, M; Franceschi, E; French, P; Frenel, JS; Golfinopoulos, V; Gorlia, T; Krause, S; Looman, J; Nuyens, S; Sanghera, P; Sepulveda, JM; Smits, M; Spruyt, M; Van Den Bent, M; Walenkamp, A; Weller, M; Whenham, N, 2020)
"We sought to determine the maximum tolerated dose (MTD) of 5-fraction stereotactic radiosurgery (SRS) with 5-mm margins delivered with concurrent temozolomide in newly diagnosed glioblastoma (GBM)."5.34A phase I/II trial of 5-fraction stereotactic radiosurgery with 5-mm margins with concurrent temozolomide in newly diagnosed glioblastoma: primary outcomes. ( Adler, JR; Azoulay, M; Chang, SD; Choi, CYH; Fujimoto, D; Gibbs, IC; Hancock, SL; Harraher, C; Harsh, GR; Hayden Gephart, M; Jacobs, LR; Li, G; Modlin, LA; Nagpal, S; Pollom, EL; Recht, LD; Seiger, K; Soltys, SG; Thomas, RP; Usoz, M; von Eyben, R; Wynne, J, 2020)
"A Pediatric Brain Tumor Consortium (PBTC) phase I/II trial of veliparib and radiation followed by veliparib and temozolomide (TMZ) was conducted in children with newly diagnosed diffuse intrinsic pontine glioma (DIPG)."5.34A phase I/II study of veliparib (ABT-888) with radiation and temozolomide in newly diagnosed diffuse pontine glioma: a Pediatric Brain Tumor Consortium study. ( Adesina, A; Ansell, P; Baxter, PA; Billups, CA; Blaney, SM; Broniscer, A; Dunkel, IJ; Fouladi, M; Giranda, V; Kilburn, L; Li, XN; Onar-Thomas, A; Paulino, A; Poussaint, TY; Quaddoumi, I; Smith, ER; Su, JM; Thompson, P, 2020)
" TTFields plus Temozolomide (TTFields/TMZ) extended survival versus TMZ alone in newly diagnosed glioblastoma (GBM) patients in the EF-14 trial."5.34Tumor treating fields plus temozolomide for newly diagnosed glioblastoma: a sub-group analysis of Korean patients in the EF-14 phase 3 trial. ( Chang, JH; Hong, YK; Kim, CY; Kim, JH; Kim, OL; Kim, SH; Nam, DH; Paek, SH, 2020)
"We performed the first clinical trial to assess VEGFR1 and 2 vaccination along with temozolomide (TMZ) -based chemoradiotherapy for the patients with primary glioblastomas."5.34Clinical and histopathological analyses of VEGF receptors peptide vaccine in patients with primary glioblastoma - a case series. ( Hikichi, T; Kawakami, Y; Kikuchi, R; Kosugi, K; Morimoto, Y; Nagashima, H; Noji, S; Oishi, Y; Sasaki, H; Sato, M; Tamura, R; Toda, M; Ueda, R; Yoshida, K, 2020)
"Ipi-Glio is a phase II, open label, randomised study of ipilimumab with temozolomide (Arm A) versus temozolomide alone (Arm B) after surgery and chemoradiotherapy in patients with recently diagnosed glioblastoma."5.34A phase II open label, randomised study of ipilimumab with temozolomide versus temozolomide alone after surgery and chemoradiotherapy in patients with recently diagnosed glioblastoma: the Ipi-Glio trial protocol. ( Blagden, S; Brooks, C; Brown, NF; Coutts, T; Elhussein, L; Holmes, J; Hoskin, P; Maughan, T; Mulholland, P; Ng, SM; Roberts, C, 2020)
"Standard of care for glioblastoma includes concurrent chemoradiation and maintenance temozolomide with tumor treatment fields (TTFields)."5.34Initial experience with scalp sparing radiation with concurrent temozolomide and tumor treatment fields (SPARE) for patients with newly diagnosed glioblastoma. ( Andrews, DW; Bar-Ad, V; Chervoneva, I; Evans, JJ; Farrell, CJ; Glass, J; Judy, K; Liu, H; Ly, M; Martinez, N; Palmer, JD; Shi, W; Song, A; Werner-Wasik, M, 2020)
"Temozolomide (TMZ) has been the standard-of-care chemotherapy for glioblastoma (GBM) patients for more than a decade."5.34Image-based metric of invasiveness predicts response to adjuvant temozolomide for primary glioblastoma. ( Bendok, BR; Doyle, T; Hawkins-Daarud, A; Hu, LS; Jackson, PR; Johnston, SK; Massey, SC; Mrugala, MM; Porter, AB; Sarkaria, JN; Singleton, KW; Swanson, KR; Vora, S; White, H; Whitmire, P, 2020)
"To report the long-term outcomes of the RTOG 0424 study of a high-risk, low-grade glioma population treated with concurrent and adjuvant temozolomide (TMZ) and radiation therapy (RT)."5.34Phase 2 Study of a Temozolomide-Based Chemoradiation Therapy Regimen for High-Risk, Low-Grade Gliomas: Long-Term Results of Radiation Therapy Oncology Group 0424. ( Bahary, JP; Barani, IJ; Bovi, JA; Chakravatri, A; D'Souza, D; Doyle, T; Fisher, BJ; Fiveash, JB; Fox, S; Howard, SP; Kwok, Y; Laack, NN; Lesser, GJ; Macdonald, DR; Mehta, MP; Michael Yu, HH; Pugh, SL; Rogers, CL; Strasser, JF; Wahl, DR; Werner-Wasik, M; Won, M, 2020)
"Standard treatment for glioblastoma is radiation with concomitant and adjuvant temozolomide for 6 cycles, although the optimal number of cycles of adjuvant temozolomide has long been a subject of debate."5.34A phase II randomized, multicenter, open-label trial of continuing adjuvant temozolomide beyond 6 cycles in patients with glioblastoma (GEINO 14-01). ( Alonso, M; Balana, C; Berrocal, A; Carrato, C; Covela, M; de Las Peñas, R; Del Barco, S; Domenech, M; Esteve, A; Estival, A; Fuster, J; Gallego, O; Gil-Gil, M; Gironés, R; Herrero, A; Luque, R; Manuel Sepúlveda, J; Martinez-García, M; Mesia, C; Munne, N; Muñoz-Langa, J; Navarro, LM; Olier, C; Peralta, S; Perez-Martín, FJ; Perez-Segura, P; Pineda, E; Sanz, C; Vaz, MA; Villa, S, 2020)
"This study aimed to explore the genetic alterations and to identify good responders in the experimental arm in the tumor samples from newly diagnosed glioblastoma (GBM) patients enrolled in JCOG0911; a randomized phase II trial was conducted to compare the efficacy of interferonβ (IFNβ) plus temozolomide (TMZ) with that of TMZ alone."5.34Genetic analysis in patients with newly diagnosed glioblastomas treated with interferon-beta plus temozolomide in comparison with temozolomide alone. ( Abe, T; Adilijiang, A; Aoki, K; Aoki, T; Arakawa, Y; Asai, A; Asano, K; Beppu, T; Hashimoto, N; Hirano, H; Hirano, M; Ishikawa, E; Ito, T; Iwadate, Y; Kayama, T; Kobayashi, H; Kumabe, T; Kurisu, K; Maeda, S; Maruyama, T; Matsumura, A; Matsuo, T; Mishima, K; Motomura, K; Mukasa, A; Muragaki, Y; Nagane, M; Nakamura, H; Nakasu, Y; Narita, Y; Natsume, A; Nishikawa, R; Ohka, F; Okuno, Y; Onishi, T; Sasaki, H; Sato, S; Shibui, S; Shinoura, N; Sugiyama, K; Sumi, M; Terasaki, M; Wakabayashi, T; Yamasaki, F; Yoshimoto, K; Yoshino, A, 2020)
"In this open-label, randomized, phase 3 clinical trial, 439 patients with glioblastoma at first recurrence following standard radiation and temozolomide therapy were enrolled, and 369 were randomized."5.34Effect of Nivolumab vs Bevacizumab in Patients With Recurrent Glioblastoma: The CheckMate 143 Phase 3 Randomized Clinical Trial. ( Ahluwalia, MS; Baehring, J; Bähr, O; Brandes, AA; Carleton, M; De Souza, P; Lim, M; Mulholland, P; Omuro, A; Phuphanich, S; Reardon, DA; Roth, P; Sahebjam, S; Sampson, J; Sepulveda, JM; Taitt, C; Tatsuoka, K; Weller, M; Wick, A; Zwirtes, R, 2020)
" In a previously-published multi-centre randomized clinical trial of 562 elderly glioblastoma patients, temozolomide plus short-course radiotherapy conferred a survival benefit over radiotherapy alone."5.34Temozolomide and seizure outcomes in a randomized clinical trial of elderly glioblastoma patients. ( Brandes, AA; Cairncross, JG; Climans, SA; Ding, K; Fay, M; Laperriere, N; Mason, WP; Menten, J; Nishikawa, R; O'Callaghan, CJ; Perry, JR; Phillips, C; Roa, W; Wick, W; Winch, C, 2020)
" Three patients (12%) were changed to standard temozolomide dosing due to side effects, including intractable nausea (n = 2) and multiple cytopenias (n = 1)."5.34Toxicity and efficacy of protracted low dose temozolomide for the treatment of low grade gliomas. ( Gasco, J; Pouratian, N; Schiff, D; Shaffrey, ME; Sherman, JH, 2007)
"Glioblastomas are malignant brain tumors that are very difficult to cure, even with aggressive therapy consisting of surgery, chemotherapy, and radiation."5.34Phosphatase and tensin homologue deficiency in glioblastoma confers resistance to radiation and temozolomide that is reversed by the protease inhibitor nelfinavir. ( Bernhard, EJ; Cerniglia, GJ; Georgescu, MM; Gupta, AK; Hahn, SM; Jiang, Z; Maity, A; Mick, R; Pore, N, 2007)
"Temozolomide treatment of high-grade tv-a gliomas provided a 14-day growth delay compared with vehicle controls."5.34Magnetic resonance imaging determination of tumor grade and early response to temozolomide in a genetically engineered mouse model of glioma. ( Hambardzumyan, D; Holland, EC; Kreger, AR; Leopold, WR; McConville, P; Moody, JB; Rehemtulla, A; Ross, BD; Woolliscroft, MJ, 2007)
"The time-to-maximum plasma concentration (tmax) of TMZ was about 1 h and the elimination half-life of terminal excretion phase (t 1/2lambda z) was about 2 h."5.34Pharmacokinetic study of temozolomide on a daily-for-5-days schedule in Japanese patients with relapsed malignant gliomas: first study in Asians. ( Adachi, J; Aoki, T; Matsutani, M; Mishima, K; Mizutani, T; Nishikawa, R; Nojima, K, 2007)
"Perifosine is an oral Akt inhibitor which exerts a marked cytotoxic effect on human tumor cell lines, and is currently being tested in several phase II trials for treatment of major human cancers."5.33Perifosine inhibits multiple signaling pathways in glial progenitors and cooperates with temozolomide to arrest cell proliferation in gliomas in vivo. ( Holland, EC; Momota, H; Nerio, E, 2005)
"Surgical cure of glioblastomas is virtually impossible and their clinical course is mainly determined by the biologic behavior of the tumor cells and their response to radiation and chemotherapy."5.33Patients with high-grade gliomas harboring deletions of chromosomes 9p and 10q benefit from temozolomide treatment. ( Beerenwinkel, N; Feiden, W; Hartmann, C; Ketter, R; Lengauer, T; Meese, E; Rahnenführer, J; Steudel, WI; Stockhammer, F; Strowitzki, M; Urbschat, S; von Deimling, A; Wemmert, S; Zang, KD, 2005)
"The ability of treatment to reduce melanoma metastatic spreading and invasion of the extracellular matrix was also tested."5.33Poly(ADP-ribose) glycohydrolase inhibitor as chemosensitiser of malignant melanoma for temozolomide. ( Forini, O; Gold, B; Graziani, G; Lacal, PM; Leonetti, C; Li, W; Muzi, A; Ruffini, F; Scarsella, M; Tentori, L; Vergati, M; Zhang, J, 2005)
"Gliomas are primary brain tumors associated with a poor prognosis partly due to resistance to conventional therapies."5.33Antiangiogenic agent, thalidomide increases the antitumor effect of single high dose irradiation (gamma knife radiosurgery) in the rat orthotopic glioma model. ( Itasaka, S; Kim, JT; Lee, JI; Nam, DH, 2006)
"Temozolomide (TMZ) has shown efficacy in the treatment of metastatic melanoma."5.33Whole brain irradiation and temozolomide based chemotherapy in melanoma brain metastases. ( Castel, T; Conill, C; Domingo-Doménech, J; Gallego, R; Jorcano, S; Malvehy, J; Puig, S; Sánchez, M; Vilella, R, 2006)
"Tamoxifen and hypericin were able to greatly increase the growth-inhibitory and apoptosis-stimulatory potency of temozolomide via the downregulation of critical cell cycle-regulatory and prosurvival components."5.33Enhancement of glioblastoma cell killing by combination treatment with temozolomide and tamoxifen or hypericin. ( Chen, TC; Gupta, V; Hofman, FM; Kardosh, A; Liebes, LF; Schönthal, AH; Su, YS; Wang, W, 2006)
"Temozolomide (TMZ) displays efficacy for the treatment of metastatic melanoma."5.32[Temozolomide in patients with melanoma brain metastases treated with whole brain irradiation]. ( Castel, T; Conill, C; Fernández-Ibiza, J; Malvehy, J; Puig, S; Sánchez, M, 2004)
" The population pharmacokinetic analysis was performed with nonlinear mixed-effect modeling software."5.32Plasma and cerebrospinal fluid population pharmacokinetics of temozolomide in malignant glioma patients. ( Buclin, T; Csajka, C; Decosterd, LA; Lejeune, F; Leyvraz, S; Ostermann, S; Stupp, R, 2004)
" In this work we investigated the effect of association of temozolomide (TMZ), an orally bioavailable alkylating agent, with three chemotherapeutic drugs, liposomal doxorubicin (DOXO), cis-platinum (CDDP)."5.32Effect of association of temozolomide with other chemotherapic agents on cell growth inhibition in glioma cell lines. ( Balzarotti, M; Boiardi, A; Calatozzolo, C; Ciusani, E; Croci, D; Salmaggi, A, 2004)
"Temozolomide (TMZ) is a methylating agent with promising antitumor efficacy for the treatment of melanomas and intermediate-grade gliomas."5.32The piperidine nitroxide Tempol potentiates the cytotoxic effects of temozolomide in human glioblastoma cells. ( Cereda, E; Gariboldi, MB; Monti, E; Ravizza, R, 2004)
"Glioblastoma is the deadliest and most prevalent brain tumor."5.32Dexamethasone protected human glioblastoma U87MG cells from temozolomide induced apoptosis by maintaining Bax:Bcl-2 ratio and preventing proteolytic activities. ( Banik, NL; Das, A; Patel, SJ; Ray, SK, 2004)
"The optimal management of high risk WHO grade II gliomas after surgery is debated including the role of initial temozolomide to delay radiotherapy and risk of cognitive defects."5.30Efficacy of initial temozolomide for high-risk low grade gliomas in a phase II AINO (Italian Association for Neuro-Oncology) study: a post-hoc analysis within molecular subgroups of WHO 2016. ( Bello, L; Bertero, L; Carapella, CM; Caroli, M; Cassoni, P; Dealis, C; Faedi, M; Marchese, G; Migliore, E; Pace, A; Pellerino, A; Rudà, R; Soffietti, R, 2019)
"To determine the efficacy of the thrombopoietin receptor agonist romiplostim for the prevention of temozolomide-induced thrombocytopenia in newly diagnosed glioblastoma."5.30Romiplostim for temozolomide-induced thrombocytopenia in glioblastoma: The PLATUM trial. ( Cartalat, S; Chinot, O; Devos, P; Di Stefano, AL; Dubois, F; Houillier, C; Le Rhun, E; Lepage, C; Reyns, N; Weller, M, 2019)
" The present standard treatment for newly diagnosed glioblastoma is maximal resection followed by chemoradiotherapy with temozolomide."5.30A multicenter randomized phase III study for newly diagnosed maximally resected glioblastoma comparing carmustine wafer implantation followed by chemoradiotherapy with temozolomide with chemoradiotherapy alone; Japan Clinical Oncology Group Study JCOG1703 ( Ichimura, K; Igaki, H; Kadota, T; Katayama, H; Kinoshita, M; Komori, T; Kumabe, T; Mizusawa, J; Narita, Y; Nishikawa, R; Saito, R; Sumi, M, 2019)
" We assessed the efficacy and safety of iniparib with standard radiotherapy and temozolomide in patients with newly diagnosed glioblastoma (GBM)."5.30Phase II Study of Iniparib with Concurrent Chemoradiation in Patients with Newly Diagnosed Glioblastoma. ( Ahluwalia, MS; Blakeley, JO; Chi, AS; Desideri, S; Eichler, A; Grossman, SA; Mikkelsen, T; Nabors, LB; Ribas, IG; Rosenfeld, MR; Ye, X, 2019)
"Patients with glioblastoma without O6-methylguanine-DNA methyltransferase (MGMT) promoter hypermethylation are unlikely to benefit from alkylating chemotherapy with temozolomide (TMZ)."5.30N2M2 (NOA-20) phase I/II trial of molecularly matched targeted therapies plus radiotherapy in patients with newly diagnosed non-MGMT hypermethylated glioblastoma. ( Bendszus, M; Berberich, A; Brors, B; Debus, J; Dettmer, S; Eisenmenger, A; Herold-Mende, C; Jones, DTW; Karapanagiotou-Schenkel, I; Kessler, T; Pfaff, E; Pfister, SM; Platten, M; Sahm, F; Unterberg, A; von Deimling, A; Wick, A; Wick, W; Winkler, F, 2019)
"Memantine, mefloquine, and metformin can be combined safely with TMZ in patients with newly diagnosed glioblastoma."5.30Phase 1 lead-in to a phase 2 factorial study of temozolomide plus memantine, mefloquine, and metformin as postradiation adjuvant therapy for newly diagnosed glioblastoma. ( Aldape, KD; Alfred Yung, WK; Conrad, CA; de Groot, JF; Gilbert, MR; Groves, MD; Hess, KR; Loghin, ME; Mammoser, AG; Maraka, S; Melguizo-Gavilanes, I; O'Brien, BJ; Penas-Prado, M; Puduvalli, VK; Sulman, EP; Tremont-Lukats, IW, 2019)
" Gliomas, which are common in dogs and also represent the majority of fatal brain tumours in humans, can be amenable to chemotherapy with temozolomide."5.30Intratumoral temozolomide in spontaneous canine gliomas: feasibility of a novel therapy using implanted microcylinders. ( Hicks, J; Holmes, S; Howerth, E; Kaplan, E; Kaplan, J; Kent, M; Platt, S; Senneca, C; Stewart, G, 2019)
"Preclinical studies have suggested promising activity for the combination of disulfiram and copper (DSF/Cu) against glioblastoma (GBM) including re-sensitization to temozolomide (TMZ)."5.30A multicenter phase II study of temozolomide plus disulfiram and copper for recurrent temozolomide-resistant glioblastoma. ( Boockvar, J; Campian, JL; Chaudhary, R; Chinnaiyan, P; Cohen, AL; Fink, K; Goldlust, S; Huang, J; Marcus, S; Wan, L, 2019)
"The treatment using hypofractionated stereotactic radiotherapy concurrent with temozolomide appeared to be safe and could significantly extend overall survival compared with historical control in complex brain metastases."5.30A Phase II Trial of Concurrent Temozolomide and Hypofractionated Stereotactic Radiotherapy for Complex Brain Metastases. ( Bi, N; Chen, X; Deng, L; Hu, C; Huang, X; Li, J; Li, Y; Liu, F; Liu, Q; Ma, Y; Tian, Y; Wang, K; Wang, W; Xiao, J; Xu, Y; Yang, S; Yi, J; Zhang, H; Zhang, Y; Zhao, R, 2019)
"In RPA V-VI glioblastoma patients both hypofractionated radiotherapy and exclusive temozolomide can be used; the purpose of this trial is to compare these treatment regimens in terms of survival and quality of life."5.30Hypofractionated radiation therapy versus chemotherapy with temozolomide in patients affected by RPA class V and VI glioblastoma: a randomized phase II trial. ( Borghetti, P; Bruni, A; Buglione, M; Fusco, V; Gatta, R; Krengli, M; Magrini, SM; Masini, L; Meduri, B; Pedretti, S; Pegurri, L; Pirtoli, L; Ricardi, U; Riva, N; Santoni, R; Scoccianti, S; Triggiani, L; Turco, E, 2019)
"The phase II GLARIUS trial assigned patients with newly diagnosed, O-6-methylguanine-DNA methyltransferase promoter non-methylated glioblastoma to experimental bevacizumab/irinotecan (BEV/IRI) or standard temozolomide (TMZ)."5.30Baseline T1 hyperintense and diffusion-restricted lesions are not linked to prolonged survival in bevacizumab-treated glioblastoma patients of the GLARIUS trial. ( Bähr, O; Belka, C; Borchers, C; Galldiks, N; Gerlach, R; Glas, M; Goldbrunner, R; Hänel, M; Hattingen, E; Hau, P; Herrlinger, U; Junold, N; Kebir, S; Krex, D; Mack, F; Proescholdt, M; Rohde, V; Sabel, M; Schäfer, N; Schaub, C; Schlegel, U; Schmidt-Graf, F; Seidel, C; Steinbach, JP; Tabatabai, G; Tzaridis, T; Vatter, H; Weller, J; Weyerbrock, A, 2019)
"Combined PET-MRI with the tracer O-(2-18F-fluoroethyl)-l-tyrosine (18F-FET) prior to re-RT was performed in recurrent glioma patients in a phase I trial."5.30Report of first recurrent glioma patients examined with PET-MRI prior to re-irradiation. ( Albert, NL; Bartenstein, P; Belka, C; Corradini, S; Fleischmann, DF; Förster, S; la Fougère, C; Niyazi, M; Rottler, M; Schwaiger, M; Siepmann, T; Unterrainer, M, 2019)
"A multicenter phase II study for assessing the efficacy and the toxicity of hypofractionated radiotherapy with SIB plus temozolomide in patients with glioblastoma was carried out by the Brain Study Group of the Italian Association of Radiation Oncology."5.27Hypofractionated radiotherapy with simultaneous integrated boost (SIB) plus temozolomide in good prognosis patients with glioblastoma: a multicenter phase II study by the Brain Study Group of the Italian Association of Radiation Oncology (AIRO). ( Buglione, M; Detti, B; Doino, D; Fiorentino, A; Fusco, V; Greto, D; Krengli, M; Livi, L; Lonardi, F; Magrini, SM; Marrazzo, L; Marzano, S; Masini, L; Migliaccio, F; Pirtoli, L; Ricardi, U; Rubino, G; Santoni, R; Scoccianti, S, 2018)
"Vorinostat combined with standard chemoradiation had acceptable tolerability in newly diagnosed glioblastoma."5.27Phase I/II trial of vorinostat combined with temozolomide and radiation therapy for newly diagnosed glioblastoma: results of Alliance N0874/ABTC 02. ( Ahluwalia, MS; Anderson, SK; Ballman, KV; Buckner, JC; Cerhan, J; Galanis, E; Gerstner, ER; Giannini, C; Grossman, SA; Jaeckle, K; Lee, EQ; Lesser, GJ; Ligon, KL; Loboda, A; Miller, CR; Moore, DF; Nebozhyn, M; Prados, M; Sarkaria, JN; Schiff, D; Wen, PY, 2018)
"In this exploratory analysis of AVAglio, a randomized phase III clinical study that investigated the addition of bevacizumab (Bev) to radiotherapy/temozolomide in newly diagnosed glioblastoma, we aim to radiologically characterize glioblastoma on therapy until progression and investigate whether the type of radiologic progression differs between treatment arms and is related to survival and molecular data."5.27Radiologic progression of glioblastoma under therapy-an exploratory analysis of AVAglio. ( Abrey, LE; Bendszus, M; Chinot, OL; Cloughesy, TF; Ellingson, BM; Garcia, J; Henriksson, R; Kickingereder, P; Mason, WP; Nishikawa, R; Nowosielski, M; Platten, M; Radbruch, A; Revil, C; Sandmann, T; Saran, F; Wick, W, 2018)
"We recently reported an acceptable safety and pharmacokinetic profile of depatuxizumab mafodotin (depatux-m), formerly called ABT-414, plus radiation and temozolomide in newly diagnosed glioblastoma (arm A)."5.27Safety, pharmacokinetics, and antitumor response of depatuxizumab mafodotin as monotherapy or in combination with temozolomide in patients with glioblastoma. ( Ansell, PJ; Butowski, N; Fichtel, L; Fischer, J; Gan, HK; Gomez, EJ; Holen, KD; Kumthekar, P; Lassman, AB; Lee, HJ; Lwin, Z; Mandich, H; Merrell, R; Munasinghe, WP; Reardon, DA; Roberts-Rapp, LA; Scott, AM; van den Bent, M; Wheeler, H; Xiong, H, 2018)
"To determine the impact on overall survival with different salvage therapies, including no treatment, reirradiation, systemic therapy, or radiation and systemic therapy, in participants of a phase 3 clinical trial evaluating dose-dense versus standard-dose temozolomide for patients with newly diagnosed glioblastoma."5.27Investigating the Effect of Reirradiation or Systemic Therapy in Patients With Glioblastoma After Tumor Progression: A Secondary Analysis of NRG Oncology/Radiation Therapy Oncology Group Trial 0525. ( Andrews, DW; Blumenthal, DT; Brown, PD; Dignam, JJ; Gilbert, MR; Hopkins, K; Howard, SP; Lessard, N; Mehta, MP; Scannell Bryan, M; Shi, W; Souhami, L; Tzuk-Shina, T; Valeinis, E; Werner-Wasik, M; Youssef, EF, 2018)
"The GLARIUS trial, which investigated the efficacy of bevacizumab (BEV)/irinotecan (IRI) compared with standard temozolomide in the first-line therapy of O6-methylguanine-DNA methyltransferase (MGMT)-nonmethylated glioblastoma, showed that progression-free survival was significantly prolonged by BEV/IRI, while overall survival was similar in both arms."5.27Quality of life in the GLARIUS trial randomizing bevacizumab/irinotecan versus temozolomide in newly diagnosed, MGMT-nonmethylated glioblastoma. ( Belka, C; Friedrich, F; Glas, M; Goldbrunner, R; Grau, S; Grauer, O; Hänel, M; Hau, P; Herrlinger, U; Kebir, S; Krex, D; Leutgeb, B; Mack, F; Nießen, M; Proescholdt, M; Ringel, F; Rohde, V; Ronellenfitsch, MW; Sabel, M; Schäfer, N; Schaub, C; Schlegel, U; Schnell, O; Steinbach, JP; Stummer, W; Tabatabai, G; Tzaridis, T; Uhl, M; Urbach, H; Vajkoczy, P; Weyerbrock, A, 2018)
"This phase II study was designed to determine the efficacy of the mammalian target of rapamycin (mTOR) inhibitor everolimus administered daily with conventional radiation therapy and chemotherapy in patients with newly diagnosed glioblastoma."5.27A randomized phase II study of everolimus in combination with chemoradiation in newly diagnosed glioblastoma: results of NRG Oncology RTOG 0913. ( Ahluwalia, MS; Ashby, LS; Chinnaiyan, P; Fiveash, JB; Kee, AY; Malone, SC; Mehta, MP; Michael Yu, HH; Mohile, NA; Rojiani, AM; Shih, HA; Stella, PJ; Stieber, VW; Wen, PY; Wendland, MM; Werner-Wasik, M; Won, M, 2018)
" We sought to study vorinostat (VOR), a histone deacetylase inhibitor, in combination with bevacizumab (BEV) and daily metronomic temozolomide (TMZ) in a Phase I/II trial in recurrent high-grade gliomas (HGGs)."5.27Phase I/II trial of vorinostat, bevacizumab, and daily temozolomide for recurrent malignant gliomas. ( Desjardins, A; Friedman, HS; Herndon, JE; Lipp, ES; McSherry, F; Miller, E; Peters, KB; Reardon, DA, 2018)
"Disulfiram has shown promising activity including proteasome inhibitory properties and synergy with temozolomide in preclinical glioblastoma (GBM) models."5.27Final results of a phase I dose-escalation, dose-expansion study of adding disulfiram with or without copper to adjuvant temozolomide for newly diagnosed glioblastoma. ( Ansstas, G; Campian, JL; DeWees, TA; Gujar, AD; Huang, J; Kim, AH; Lockhart, AC; Tran, DD; Tsien, C, 2018)
"This secondary analysis of EF-14, a phase 3 randomized clinical trial, compares TTFields and temozolomide or temozolomide alone in 695 patients with glioblastoma after completion of radiochemotherapy."5.27Influence of Treatment With Tumor-Treating Fields on Health-Related Quality of Life of Patients With Newly Diagnosed Glioblastoma: A Secondary Analysis of a Randomized Clinical Trial. ( Bruna, J; Chen, TC; David, C; Desai, R; Dirven, L; Easaw, JC; Honnorat, J; Hottinger, AF; Idbaih, A; Kanner, AA; Kew, Y; Kim, CY; Kirson, ED; Lavy-Shahaf, G; Ram, Z; Roth, P; Sroubek, J; Stupp, R; Taillibert, S; Taphoorn, MJB; Toms, SA; Villano, JL; Weinberg, U, 2018)
"Concomitant radiochemotherapy followed by six cycles of temozolomide (= short term) is considered as standard therapy for adults with newly diagnosed glioblastoma."5.27Cost-effectiveness of the long-term use of temozolomide for treating newly diagnosed glioblastoma in Germany. ( Arefian, H; Hartmann, M; Kalff, R; Maschmann, J; Walter, J; Waschke, A, 2018)
"The European Organisation for Research and Treatment of Cancer (EORTC) 22033-26033 clinical trial (NCT00182819) investigated whether initial temozolomide (TMZ) chemotherapy confers survival advantage compared with radiotherapy (RT) in low-grade glioma (LGG) patients."5.27Expression-based intrinsic glioma subtypes are prognostic in low-grade gliomas of the EORTC22033-26033 clinical trial. ( Balana, C; Baumert, BG; Ben Hassel, M; Brandes, AA; Chinot, O; Dhermain, F; Enting, R; Erdem-Eraslan, L; French, PJ; Gao, Y; Gijtenbeek, JMM; Gorlia, T; Hegi, ME; Hoang-Xuan, K; Kros, JM; Mason, WP; Ryan, GF; Sillevis Smitt, P; Stupp, R; van den Bent, MJ; van Linde, ME; von Deimling, A; Vos, M; Weenink, B, 2018)
"ACRIN 6686/RTOG 0825 was a phase III trial of conventional chemoradiation plus adjuvant temozolomide with bevacizumab or without (placebo) in newly diagnosed glioblastoma."5.27Prognostic value of contrast enhancement and FLAIR for survival in newly diagnosed glioblastoma treated with and without bevacizumab: results from ACRIN 6686. ( Barboriak, DP; Boxerman, JL; Gilbert, MR; Marques, H; Mohan, S; Rogg, JM; Safriel, Y; Sorensen, AG; Wolf, RL; Zhang, Z, 2018)
"1/CATNON intergroup trial was designed to evaluate the impact on concurrent and adjuvant temozolomide chemotherapy in newly diagnosed non-1p/19q deleted anaplastic gliomas."5.27Radiotherapy quality assurance for the RTOG 0834/EORTC 26053-22054/NCIC CTG CEC.1/CATNON intergroup trial "concurrent and adjuvant temozolomide chemotherapy in newly diagnosed non-1p/19q deleted anaplastic glioma": Individual case review analysis. ( Abrunhosa-Branquinho, AN; Bar-Deroma, R; Baumert, BG; Clementel, E; Collette, S; Feuvret, L; Hurkmans, CW; Liu, Y; Van Beek, K; van den Bent, M; Weber, DC, 2018)
"In this phase II study, we investigate clinical outcomes and tolerability of hypofractionated radiotherapy (HRT) combined with temozolomide (TMZ) to treat elderly patients with glioblastoma (GBM)."5.27Interim Results of a Phase II Study of Hypofractionated Radiotherapy with Concurrent Temozolomide Followed by Adjuvant Temozolomide in Patients over 70 Years Old with Newly Diagnosed Glioblastoma. ( Amsbaugh, M; Boakye, M; Burton, E; Hattab, EM; Nelson, M; Ugiliweneza, B; Williams, B; Woo, S; Yusuf, M, 2018)
"Adult patients with intermediate- to high-grade glioma on adjuvant temozolomide (TMZ) with facilities for live video call were invited to participate in the study."5.27Shadow study: randomized comparison of clinic with video follow-up in glioma undergoing adjuvant temozolomide therapy. ( Chakraborty, S; Chandrasekharan, A; Dsouza, H; Goda, JS; Gupta, T; Jalali, R; Krishnatry, R; M, C; Pande, N; Patil, VM; Tonse, R; Vallathol, DH, 2018)
"In this study, MGMT promoter methylation was an independent prognostic biomarker of high-risk, low-grade glioma treated with temozolomide and radiotherapy."5.27Association of MGMT Promoter Methylation Status With Survival Outcomes in Patients With High-Risk Glioma Treated With Radiotherapy and Temozolomide: An Analysis From the NRG Oncology/RTOG 0424 Trial. ( Aldape, KD; Ashby, LS; Bahary, JP; Becker, AP; Bell, EH; Chakraborty, AR; Chakravarti, A; Fabian, D; Fisher, BJ; Fleming, J; Gray, HJ; Kwok, Y; Laack, NN; Lesser, GJ; Liu, Z; Macdonald, DR; McElroy, JP; Mehta, MP; Robins, HI; Schultz, CJ; Walker, EM; Werner-Wasik, M; Yu, HM; Zhang, P, 2018)
"Mibefradil (MIB), previously approved for treatment of hypertension, is a selective T-type calcium channel blocker with preclinical activity in high-grade gliomas (HGGs)."5.24Timed sequential therapy of the selective T-type calcium channel blocker mibefradil and temozolomide in patients with recurrent high-grade gliomas. ( Desai, AS; Desideri, S; Fisher, JD; Grossman, SA; Holdhoff, M; Leal, J; Lesser, GJ; Lieberman, FS; Lodge, MA; Nabors, LB; Read, WL; Schiff, D; Supko, JG; Wahl, RL; Walbert, T; Ye, X, 2017)
"This post hoc analysis of the EF-14 trial (NCT00916409) of tumor-treating fields (TTFields) plus temozolomide versus temozolomide alone in newly diagnosed glioblastoma compared the efficacy of TTFields plus chemotherapy (physician's choice) versus chemotherapy alone after first recurrence."5.24Tumor-treating fields plus chemotherapy versus chemotherapy alone for glioblastoma at first recurrence: a post hoc analysis of the EF-14 trial. ( Kesari, S; Ram, Z, 2017)
"We report a longitudinal assessment of health-related quality of life (HRQOL) in patients with glioblastoma (GBM) treated on a prospective dose escalation trial of 5-fraction stereotactic radiosurgery (25-40 Gy in 5 fractions) with concurrent and adjuvant temozolomide."5.24Phase 1/2 Trial of 5-Fraction Stereotactic Radiosurgery With 5-mm Margins With Concurrent and Adjuvant Temozolomide in Newly Diagnosed Supratentorial Glioblastoma: Health-Related Quality of Life Results. ( Adler, JR; Azoulay, M; Chang, SD; Choi, CYH; Fujimoto, D; Gibbs, IC; Hancock, SL; Harraher, C; Harsh, GR; Jacobs, LR; Li, G; Modlin, LA; Nagpal, S; Pollom, EL; Recht, LD; Seiger, K; Soltys, SG; Thomas, RP; Tupper, L; von Eyben, R; Wynne, J, 2017)
"Bevacizumab plus bi-weekly temozolomide was well tolerated and may be a salvage regimen to be considered in a subset of patients with recurrent glioblastoma."5.24Phase II study of bi-weekly temozolomide plus bevacizumab for adult patients with recurrent glioblastoma. ( Ahmadi, MM; Badruddoja, MA; Kuzma, K; Mahadevan, D; Norton, T; Pazzi, M; Sanan, A; Schroeder, K; Scully, T, 2017)
"We characterized health-related quality of life (HRQoL), cognitive, and functional status in newly diagnosed glioblastoma (GBM) patients receiving Tumor treating fields (TTFields) with temozolomide (TMZ) versus TMZ alone in a planned interim analysis of a randomized phase III trial [NCT00916409], which showed significant improvement in progression-free and overall survival with TTFields/TMZ."5.24Health-related quality of life, cognitive screening, and functional status in a randomized phase III trial (EF-14) of tumor treating fields with temozolomide compared to temozolomide alone in newly diagnosed glioblastoma. ( Avgeropoulos, N; Benouaich-Amiel, A; David, C; Demireva, P; Goldlust, S; Kanner, AA; Mehdorn, M; Pannullo, S; Salmaggi, A; Silvani, A; Zhu, JJ, 2017)
"While our study failed to meet the primary endpoint for objective radiographic response, patients with high-risk low-grade glioma receiving adjuvant temozolomide demonstrated a high rate of radiographic stability and favorable survival outcomes while meaningfully delaying radiotherapy."5.24Chemotherapy for adult low-grade gliomas: clinical outcomes by molecular subtype in a phase II study of adjuvant temozolomide. ( Berger, MS; Butowski, N; Chang, SM; Clarke, JL; Costello, JF; Dayal, M; Haas-Kogan, DA; Lin, Y; Molinaro, AM; Nelson, S; Perry, A; Phillips, JJ; Prados, M; Wahl, M, 2017)
" We evaluated the efficacy and safety of CIK cell immunotherapy with radiotherapy-temozolomide (TMZ) for the treatment of newly diagnosed glioblastomas."5.24Phase III randomized trial of autologous cytokine-induced killer cell immunotherapy for newly diagnosed glioblastoma in Korea. ( Chang, JH; Chung, YG; Kang, SH; Kim, CH; Kim, JH; Kim, JM; Koh, YC; Kong, DS; Lee, JW; Lim, YJ; Nam, DH, 2017)
"The primary objective of this study was to compare the overall survival (OS) of patients with anaplastic astrocytoma (AA) treated with radiotherapy (RT) and either temozolomide (TMZ) or a nitrosourea (NU)."5.24Phase III randomized study of radiation and temozolomide versus radiation and nitrosourea therapy for anaplastic astrocytoma: results of NRG Oncology RTOG 9813. ( Aldape, KD; Bahary, JP; Barger, GR; Belanger, K; Bell, EH; Brachman, D; Brown, PD; Cairncross, JG; Chakravarti, A; Chang, S; Dolinskas, CA; Gilbert, MR; Hunter, G; Jaeckle, K; Mehta, M; Penas-Prado, M; Robins, HI; Schiff, D; Schultz, C; Shih, H; Werner-Wasik, M; Zhang, P, 2017)
"We performed a phase 2 trial of neoadjuvant temozolomide (TMZ), followed by hypofractionated accelerated radiation therapy (HART) with concurrent TMZ, and adjuvant TMZ in patients with newly diagnosed glioblastoma to determine whether neoadjuvant TMZ would safely improve outcomes in this group of patients prior to subsequent cytotoxic therapy."5.24A Phase 2 Trial of Neoadjuvant Temozolomide Followed by Hypofractionated Accelerated Radiation Therapy With Concurrent and Adjuvant Temozolomide for Patients With Glioblastoma. ( Abdulkarim, B; Corredor, AG; Guiot, MC; Owen, S; Panet-Raymond, V; Petrecca, K; Shenouda, G; Souhami, L, 2017)
"The purpose of this study was to determine the maximum tolerated dose (MTD), recommended phase II dose (RPTD), safety, and pharmacokinetics of ABT-414 plus radiation and temozolomide in newly diagnosed glioblastoma."5.24Efficacy and safety results of ABT-414 in combination with radiation and temozolomide in newly diagnosed glioblastoma. ( Ansell, P; Fichtel, L; Fischer, J; Gan, HK; Gomez, E; Holen, KD; Kumthekar, P; Lassman, AB; Lee, HJ; Mandich, H; Merrell, R; Munasinghe, W; Reardon, DA; Roberts-Rapp, L; Scott, AM; Sulman, EP; van den Bent, M; Xiong, H, 2017)
"There is a need for a more refined, molecularly based classification model for glioblastoma (GBM) in the temozolomide era."5.24Molecular-Based Recursive Partitioning Analysis Model for Glioblastoma in the Temozolomide Era: A Correlative Analysis Based on NRG Oncology RTOG 0525. ( Aldape, K; Barnholtz-Sloan, JS; Becker, AP; Bell, EH; Blumenthal, DT; Brachman, D; Bredel, M; Brown, PD; Chakravarti, A; Curran, W; Flickinger, J; Gilbert, MR; Glass, J; Grosu, AL; Klimowicz, AC; Lee, RJ; Magliocco, A; McElroy, JP; Mehta, M; Pugh, SL; Robe, P; Salavaggione, AL; Souhami, L; Stupp, R; Won, M, 2017)
"Temozolomide (TMZ) is an imidazotetrazine prodrug used to treat glioblastoma multiforme."5.22Temozolomide: An Overview of Biological Properties, Drug Delivery Nanosystems, and Analytical Methods. ( Carvalho, SG; Chorilli, M; Di Filippo, LD; Dutra, JAP; Luiz, MT; Tavares Junior, AG, 2022)
"Temozolomide (TMZ), an imidazotetrazine, is a second-generation DNA alkylating agent used as a first-line treatment of glioblastoma multiforme (GBM)."5.22Polymeric and small molecule-conjugates of temozolomide as improved therapeutic agents for glioblastoma multiforme. ( Chitkara, D; Jatyan, R; Karthik, YG; Mittal, A; Sahel, DK; Singh, P, 2022)
"To evaluate the safety and efficacy of nimotuzumab, a humanized monoclonal antibody specific for the epidermal growth factor receptor (EGFR), in combination with temozolomide (TMZ) and radiation therapy (RT) in the treatment of newly diagnosed glioblastoma (GBM) in Chinese patients."5.22Nimotuzumab, a humanized monoclonal antibody specific for the EGFR, in combination with temozolomide and radiation therapy for newly diagnosed glioblastoma multiforme: First results in Chinese patients. ( Chen, S; Dai, JZ; Pan, L; Sheng, XF; Wang, Y, 2016)
"Survival for glioblastoma (GBM) patients with an unmethyated MGMT promoter in their tumor is generally worse than methylated MGMT tumors, as temozolomide (TMZ) response is limited."5.22A phase II study of bevacizumab and erlotinib after radiation and temozolomide in MGMT unmethylated GBM patients. ( Aldape, K; Chamberlain, M; Conrad, C; De Groot, J; Giglio, P; Gilbert, MR; Grimm, S; Groves, M; Hu, J; Liu, D; Loghin, M; Merrell, R; Paleologos, N; Phuphanich, S; Puduvalli, VK; Rademaker, A; Raizer, JJ; Rudnick, J; Tremont-Lukats, IW; Vaillant, B; Vick, N; Yuan, Y; Yung, WK, 2016)
"We report on a phase II clinical trial to determine the effect of a concurrent ultra-fractionated radiotherapy and temozolomide treatment in inoperable glioblastoma patients."5.22A concurrent ultra-fractionated radiation therapy and temozolomide treatment: A promising therapy for newly diagnosed, inoperable glioblastoma. ( Beauchesne, P; Bernier, V; Carnin, C; Faure, G; Gorlia, T; Noel, G; Pedeux, R; Quetin, P; Quillien, V, 2016)
"This study tested the hypothesis that ABT-888 (velparib), a poly (ADP-ribose) polymerase (PARP) inhibitor, can modulate temozolomide (TMZ) resistance in recurrent TMZ refractory glioblastoma patients."5.22A randomized phase I/II study of ABT-888 in combination with temozolomide in recurrent temozolomide resistant glioblastoma: an NRG oncology RTOG group study. ( Cavaliere, R; Chakravarti, A; Chmura, SJ; Colman, H; de Groot, JF; Gilbert, MR; Grimm, SA; Kee, AY; Kesari, S; Krauze, A; Lieberman, FS; Mehta, M; Mohile, N; Robins, HI; Trotti, AM; Wang, F; Zhang, P, 2016)
"This phase II study was conducted to determine the efficacy and safety of metronomic temozolomide (TMZ) in combination with irinotecan in glioblastoma (GB) at first relapse."5.22Phase II trial of irinotecan and metronomic temozolomide in patients with recurrent glioblastoma. ( Balañá, C; Benavides, M; Fleitas, T; Gallego, O; Gil-Gil, M; Martínez-Sales, V; Palomero, I; Pérez-Segura, P; Reche, E; Reynés, G; Vaz, MA; Vila, V, 2016)
"Cabozantinib inhibits mesenchymal-epithelial transition factor (MET) and vascular endothelial growth factor receptor 2 (VEGFR2) and has demonstrated activity in patients with recurrent glioblastoma, warranting evaluation of the addition of cabozantinib to radiotherapy (RT) and temozolomide (TMZ) for patients with newly diagnosed high-grade glioma."5.22Phase 1 dose escalation trial of the safety and pharmacokinetics of cabozantinib concurrent with temozolomide and radiotherapy or temozolomide after radiotherapy in newly diagnosed patients with high-grade gliomas. ( Chamberlain, MC; Cloughesy, T; Desjardins, A; Glantz, M; Mikkelsen, T; Reardon, DA; Schiff, D; Wen, PY, 2016)
"Adding temozolomide (TMZ) to radiation for patients with newly-diagnosed anaplastic astrocytomas (AAs) is common clinical practice despite the lack of prospective studies demonstrating a survival advantage."5.22The role of temozolomide in the management of patients with newly diagnosed anaplastic astrocytoma: a comparison of survival in the era prior to and following the availability of temozolomide. ( Abuali, I; Grossman, SA; Lu, Y; Strowd, RE; Ye, X, 2016)
"The proposed use of bevacizumab with radiotherapy/temozolomide for newly diagnosed glioblastoma raised potential safety concerns."5.22Bevacizumab, temozolomide, and radiotherapy for newly diagnosed glioblastoma: comprehensive safety results during and after first-line therapy. ( Chinot, OL; Cloughesy, T; Dhar, S; Garcia, J; Henriksson, R; Mason, W; Nishikawa, R; Pozzi, E; Saran, F; Wick, W, 2016)
"Following maximal surgical resection, newly diagnosed children with nonmetastatic high-grade glioma underwent involved field radiotherapy with concurrent temozolomide."5.22Phase 2 study of concurrent radiotherapy and temozolomide followed by temozolomide and lomustine in the treatment of children with high-grade glioma: a report of the Children's Oncology Group ACNS0423 study. ( Brat, DJ; Burger, PC; Buxton, A; Cohen, KJ; Eckel, SP; Hamilton, RL; Jakacki, RI; Krailo, MD; Lavey, RS; Pollack, IF; Rosenblum, MK; Zhou, T, 2016)
"To evaluate the maximum tolerated dose of simultaneous integrated-boost intensity-modulated radiotherapy (SIB-IMRT) associated with temozolomide in patients with glioblastoma."5.22A phase I dose escalation study using simultaneous integrated-boost IMRT with temozolomide in patients with unifocal glioblastoma. ( Bernier, V; Blanchard, N; Bonnetain, F; Dalban, C; Lagneau, É; Maingon, P; Mazoyer, F; Mirjolet, C; Noël, G; Truc, G, 2016)
" Patients with MGMT unmethylated glioblastoma (n = 111) were randomized 1:1 between standard chemo-radiotherapy with temozolomide or radiotherapy plus weekly temsirolimus (25 mg)."5.22Phase II Study of Radiotherapy and Temsirolimus versus Radiochemotherapy with Temozolomide in Patients with Newly Diagnosed Glioblastoma without MGMT Promoter Hypermethylation (EORTC 26082). ( Bady, P; Brandes, AA; Campone, M; Frenel, JS; Golfinopoulos, V; Gorlia, T; Hamou, MF; Hegi, ME; Homicsko, K; Hopkins, K; Kosch, M; Lhermitte, B; Marosi, C; Pesce, G; Platten, M; Ricard, D; Roth, P; Steuve, J; Stupp, R; Taphoorn, MJ; van den Bent, MJ; Villa, S; Weller, M; Weyerbrock, A; Wick, A; Wick, W, 2016)
"Temozolomide chemotherapy versus radiotherapy in patients with a high-risk low-grade glioma has been shown to have no significant effect on progression-free survival."5.22Health-related quality of life in patients with high-risk low-grade glioma (EORTC 22033-26033): a randomised, open-label, phase 3 intergroup study. ( Back, M; Baumert, BG; Borchers, C; Bottomley, A; Brandes, AA; Bromberg, JEC; Chinot, O; Coens, C; Enting, RH; Golfinopoulos, V; Gorlia, T; Hassel, MB; Hau, P; Hoang-Xuan, K; Kantor, G; Klein, M; Mason, WP; Reijneveld, JC; Reni, M; Ryan, G; Smits, A; Stupp, R; Taphoorn, MJB; Thiessen, B; Verger, E; Wick, A, 2016)
"Overall, there was no significant difference in progression-free survival in patients with low-grade glioma when treated with either radiotherapy alone or temozolomide chemotherapy alone."5.22Temozolomide chemotherapy versus radiotherapy in high-risk low-grade glioma (EORTC 22033-26033): a randomised, open-label, phase 3 intergroup study. ( Balana, C; Baumert, BG; Brandes, AA; Bravo-Marques, J; Bromberg, JE; Capper, D; Chinot, O; Clement, PM; Dhermain, F; Dif, N; Enting, R; Feuvret, L; Gijtenbeek, JMM; Gorlia, T; Hartmann, C; Hassel, MB; Hegi, ME; Hoang-Xuan, K; Kantor, G; Kros, JM; Kurscheid, S; Lacombe, D; Marosi, C; Mason, WP; Nordal, RA; Rees, J; Reijneveld, JC; Reni, M; Rossiter, JP; Ryan, G; Stupp, R; Taphoorn, MJB; Thiessen, B; Tzuk-Shina, T; van den Bent, MJ; von Deimling, A; Wick, W, 2016)
"Temozolomide (TMZ) administered daily with radiation therapy (RT) for 6 weeks, followed by adjuvant TMZ for 6 cycles, is the standard therapy for newly diagnosed glioblastoma (GBM) patients."5.20Clinical and Genetic Factors Associated With Severe Hematological Toxicity in Glioblastoma Patients During Radiation Plus Temozolomide Treatment: A Prospective Study. ( Amadori, A; Berti, F; Bertorelle, R; Della Puppa, A; Farina, P; Lombardi, G; Marcato, R; Rumiato, E; Sacchetto, V; Saggioro, D; Zagonel, V; Zustovich, F, 2015)
"This phase I/II trial evaluated the maximum tolerated dose (MTD) and pharmacokinetics of afatinib plus temozolomide as well as the efficacy and safety of afatinib as monotherapy (A) or with temozolomide (AT) vs temozolomide monotherapy (T) in patients with recurrent glioblastoma (GBM)."5.20Phase I/randomized phase II study of afatinib, an irreversible ErbB family blocker, with or without protracted temozolomide in adults with recurrent glioblastoma. ( Cong, J; Cseh, A; Eisenstat, DD; Fu, Y; Kavan, P; Mason, WP; Mathieu, D; Nabors, LB; Perry, JR; Phuphanich, S; Reardon, DA; Shapiro, W; Wind, S, 2015)
"Chemoradiation, followed by adjuvant temozolomide, is the standard treatment for newly diagnosed glioblastoma."5.20Randomized phase II adjuvant factorial study of dose-dense temozolomide alone and in combination with isotretinoin, celecoxib, and/or thalidomide for glioblastoma. ( Aldape, KD; Chang, EL; Colman, H; Conrad, CA; De Groot, JF; Fisch, MJ; Floyd, JD; Giglio, P; Gilbert, MR; Gonzalez, J; Groves, MD; Hess, KR; Hsu, SH; Lagrone, LW; Levin, VA; Loghin, ME; Mahajan, A; Penas-Prado, M; Puduvalli, VK; Salacz, ME; Volas-Redd, G; Woo, SY; Yung, WK, 2015)
"To improve the therapeutic index of whole-brain radiation therapy (WBRT) in the treatment of brain metastases (BM) from breast cancer, we investigated the efficacy and safety of WBRT combined with temozolomide (TMZ) in this population."5.20Phase II randomized study of whole-brain radiation therapy with or without concurrent temozolomide for brain metastases from breast cancer. ( Bourgier, C; Cao, KI; Gerber, S; Gobillion, A; Kirova, YM; Le Scodan, R; Lebas, N; Levy, C; Pierga, JY; Savignoni, A, 2015)
" We evaluated the efficacy and toxicity of hypofractionated intensity-modulated radiation therapy with concurrent and adjuvant temozolomide and bevacizumab in patients with newly diagnosed glioblastoma."5.20Phase II trial of hypofractionated intensity-modulated radiation therapy combined with temozolomide and bevacizumab for patients with newly diagnosed glioblastoma. ( Carlson, JA; Chen, C; Damek, DM; Gaspar, LE; Kavanagh, BD; Kleinschmidt-DeMasters, BK; Lillehei, KO; Ney, DE; Reddy, K; Waziri, AE, 2015)
"Patients with a newly diagnosed glioblastoma multiforme (GBM) have a high risk of recurrent disease with a dismal outcome despite intensive treatment of sequential surgery and chemoradiotherapy with temozolomide (TMZ), followed by TMZ as a single agent."5.20Bevacizumab in combination with radiotherapy and temozolomide for patients with newly diagnosed glioblastoma multiforme. ( Reijneveld, JC; Richel, DJ; Stalpers, LJ; van Furth, WR; van Linde, ME; Verheul, HM; Verhoeff, JJ, 2015)
"Rindopepimut and standard adjuvant temozolomide chemotherapy were administered to 65 patients with newly diagnosed EGFRvIII-expressing (EGFRvIII+) glioblastoma after gross total resection and chemoradiation."5.20A phase II, multicenter trial of rindopepimut (CDX-110) in newly diagnosed glioblastoma: the ACT III study. ( Archer, GE; Baehring, JM; Bigner, DD; Cruickshank, S; Davis, TA; Green, JA; Groves, MD; Heimberger, AB; Jensen, R; Keler, T; Lai, RK; Mrugala, MM; Paleologos, NA; Reardon, DA; Recht, LD; Sampson, JH; Schuster, J; Sloan, A, 2015)
"Rechallenge with temozolomide (TMZ) at first progression of glioblastoma after temozolomide chemoradiotherapy (TMZ/RT→TMZ) has been studied in retrospective and single-arm prospective studies, applying temozolomide continuously or using 7/14 or 21/28 days schedules."5.20MGMT Promoter Methylation Is a Strong Prognostic Biomarker for Benefit from Dose-Intensified Temozolomide Rechallenge in Progressive Glioblastoma: The DIRECTOR Trial. ( Bähr, O; Felsberg, J; Goldbrunner, R; Hau, P; Herrlinger, U; Homicsko, K; Hüsing, J; Kästner, B; Ketter, R; Kollias, S; Marosi, C; Meixensberger, J; Nikkhah, G; Pichler, J; Platten, M; Reifenberger, G; Sabel, MC; Schlegel, U; Schnell, O; Steinbach, JP; Stupp, R; Tabatabai, G; Tonn, JC; Vajkoczy, P; Weller, M; Wick, A; Wick, W; Wirsching, HG, 2015)
"Radiation Therapy Oncology Group (RTOG) 0424 was a phase 2 study of a high-risk low-grade glioma (LGG) population who were treated with temozolomide (TMZ) and radiation therapy (RT), and outcomes were compared to those of historical controls."5.20Phase 2 study of temozolomide-based chemoradiation therapy for high-risk low-grade gliomas: preliminary results of Radiation Therapy Oncology Group 0424. ( Bahary, JP; Brachman, DG; Chakravarti, A; Coons, SW; Fisher, BJ; Hu, C; Lesser, GJ; Liu, J; Macdonald, DR; Mehta, M; Ryu, S; Werner-Wasik, M, 2015)
"To investigate the safety of combined Wilms tumor 1 peptide vaccination and temozolomide treatment of glioblastoma, a phase I clinical trial was designed."5.20Wilms tumor 1 peptide vaccination combined with temozolomide against newly diagnosed glioblastoma: safety and impact on immunological response. ( Arita, N; Chiba, Y; Hashimoto, N; Hosen, N; Izumoto, S; Kagawa, N; Kijima, N; Kinoshita, M; Morimoto, S; Morita, S; Nakajima, H; Nishida, S; Oji, Y; Oka, Y; Sakamoto, J; Sugiyama, H; Tsuboi, A; Yoshimine, T, 2015)
"The purpose of phase 1 was to determine the maximum tolerated dose (MTD) of motexafin gadolinium (MGd) given concurrently with temozolomide (TMZ) and radiation therapy (RT) in patients with newly diagnosed supratentorial glioblastoma multiforme (GBM)."5.20Phase 1/2 trials of Temozolomide, Motexafin Gadolinium, and 60-Gy fractionated radiation for newly diagnosed supratentorial glioblastoma multiforme: final results of RTOG 0513. ( Ashby, LS; Bovi, JA; Brachman, DG; Curran, WP; Dunbar, EM; Narayan, S; Pugh, SL; Robins, HI; Rockhill, JK; Thomas, TA; Won, M, 2015)
"Temozolomide (TMZ) and BCNU have demonstrated anti-glioma synergism in preclinical models."5.20BCNU wafer placement with temozolomide (TMZ) in the immediate postoperative period after tumor resection followed by radiation therapy with TMZ in patients with newly diagnosed high grade glioma: final results of a prospective, multi-institutional, phase ( Ashby, L; Asher, AL; Blaker, BD; Boltes, P; Brick, W; Burri, SH; Heideman, BE; Judy, K; Kelly, R; Norton, HJ; Prabhu, RS; Sumrall, AL; Symanowski, JT; Wiggins, WF, 2015)
"This phase I study aimed to evaluate safety, maximum tolerated dose, pharmacokinetics, pharmacodynamics, and preliminary efficacy of voxtalisib (SAR245409, XL765), a pan-class I phosphoinositide 3-kinase (PI3K) and mammalian target of rapamycin (mTOR) inhibitor, in combination with temozolomide (TMZ), with or without radiation therapy (RT), in patients with high-grade glioma."5.20Phase I dose-escalation study of the PI3K/mTOR inhibitor voxtalisib (SAR245409, XL765) plus temozolomide with or without radiotherapy in patients with high-grade glioma. ( Ahluwalia, MS; Cloughesy, TF; Egile, C; Fathallah-Shaykh, HM; Jiang, J; Lager, JJ; Laird, AD; Mohile, N; Omuro, A; Tang, J; Wen, PY, 2015)
"The aim of this prospective and multicentric phase II study was to evaluate the efficacy and safety of temozolomide (TMZ) and bevacizumab (BV) in patients (pts) with recurrent glioblastoma (GB), previously treated with chemoradiotherapy and at least three cycles of adjuvant TMZ."5.20A phase II study of feasibility and toxicity of bevacizumab in combination with temozolomide in patients with recurrent glioblastoma. ( Balañá, C; Belda-Iniesta, C; Berrocal, A; Capellades, J; Gallego, O; Gil-Gil, M; La Orden, B; Ordoñez, JM; Pérez-Segura, P; Reynés, G; Sepúlveda, JM, 2015)
"We report on the long-term results of a phase II study of pre-irradiation temozolomide followed by concurrent temozolomide and radiotherapy (RT) in patients with newly diagnosed anaplastic oligodendroglioma (AO) and mixed anaplastic oligoastrocytoma."5.20Phase II trial of pre-irradiation and concurrent temozolomide in patients with newly diagnosed anaplastic oligodendrogliomas and mixed anaplastic oligoastrocytomas: long term results of RTOG BR0131. ( Brachman, DG; Giannini, C; Hu, C; Jenkins, RB; Laack, NN; Macdonald, DR; Mehta, MP; Peereboom, DM; Shrieve, DC; Souhami, L; Suh, JH; Vogelbaum, MA, 2015)
"Valproic acid (VPA) is an antiepileptic agent with histone deacetylase inhibitor (HDACi) activity shown to sensitize glioblastoma (GBM) cells to radiation in preclinical models."5.20A Phase 2 Study of Concurrent Radiation Therapy, Temozolomide, and the Histone Deacetylase Inhibitor Valproic Acid for Patients With Glioblastoma. ( Camphausen, K; Chang, MG; Fine, HA; Holdford, DJ; Krauze, AV; Myrehaug, SD; Shih, J; Smith, S; Tofilon, PJ, 2015)
"In this multicenter, double-blind trial, adults with unresectable stage III or IV metastatic melanoma were randomized 1:1:1 to TMZ plus veliparib 20 or 40 mg, or placebo twice daily."5.20Randomized phase II study evaluating veliparib (ABT-888) with temozolomide in patients with metastatic melanoma. ( Chyla, B; Daud, A; Falotico, N; Friedlander, P; Giranda, VL; Hamid, O; Jiang, F; Luo, Y; McArthur, GA; McKee, M; McKeegan, E; Middleton, MR; Mostafa, NM; Plummer, R; Qian, J; Zhu, M, 2015)
"Iniparib is a prodrug that converts to highly reactive cytotoxic metabolites intracellularly with activity in preclinical glioma models."5.20Phase I study of iniparib concurrent with monthly or continuous temozolomide dosing schedules in patients with newly diagnosed malignant gliomas. ( Blakeley, JO; Chi, AS; Desideri, S; Emmons, G; Garcia Ribas, I; Grossman, SA; Mikkelsen, T; Nabors, LB; Peereboom, D; Rosenfeld, MR; Supko, JG; Ye, X, 2015)
"To evaluate the efficacy and safety of TTFields used in combination with temozolomide maintenance treatment after chemoradiation therapy for patients with glioblastoma."5.20Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial. ( Barnett, GH; Caroli, M; Chen, TC; Desai, R; Engelhard, HH; Fink, KL; Hegi, ME; Henson, JW; Honnorat, J; Hottinger, AF; Idbaih, A; Kanner, AA; Kesari, S; Kew, Y; Kirson, ED; Landolfi, J; Lieberman, F; Palti, Y; Ram, Z; Silvani, A; Sroubek, J; Steinberg, DM; Stupp, R; Taillibert, S; Taylor, LP; Toms, SA; Tran, DD; Tran, ND; Weinberg, U; Zhu, JJ, 2015)
"To evaluate the efficacy of limited margins intensity-modulated radiotherapy (IMRT) with temozolomide chemotherapy in patients with malignant glioma, and explore the prognostic factors of malignant glioma."5.20[Randomized controlled study of limited margins IMRT and temozolomide chemotherapy in patients with malignant glioma]. ( Cao, Y; Sun, J; Yang, X; Zhang, W, 2015)
"Adult patients with newly surgical diagnosed glioblastoma were randomly assigned to receive either temozolomide or semustine after radiation treatment."5.19Gain of function of mutant TP53 in glioblastoma: prognosis and response to temozolomide. ( Chen, JX; Liu, JP; Liu, YH; Mao, Q; Wang, X; You, C, 2014)
" We sought to determine whether the addition of a vascular endothelial growth factor (VEGF) signaling inhibitor (cediranib) to conventional CRT had an impact on the frequency of PsP, by comparing two groups of patients with newly diagnosed glioblastoma before, during, and after CRT."5.19Low incidence of pseudoprogression by imaging in newly diagnosed glioblastoma patients treated with cediranib in combination with chemoradiation. ( Batchelor, TT; Emblem, KE; Gerstner, ER; Jain, RK; Jennings, D; Kalpathy-Cramer, J; Pinho, MC; Polaskova, P; Rosen, BR; Sorensen, AG; Wen, PY, 2014)
"We conducted a phase I study to determine (a) the maximum tolerated dose of peri-radiation therapy temozolomide (TMZ) and (b) the safety of a selected hypofractionated intensity modulated radiation therapy (HIMRT) regimen in glioblastoma multiforme (GBM) patients."5.19Hypofractionated intensity modulated radiotherapy with temozolomide in newly diagnosed glioblastoma multiforme. ( Ammirati, M; Chotai, S; Grecula, J; Lamki, T; Newton, H; Wei, L, 2014)
"The integrin antagonist cilengitide has been explored as an adjunct with anti-angiogenic properties to standard of care temozolomide chemoradiotherapy (TMZ/RT → TMZ) in newly diagnosed glioblastoma."5.19Cilengitide treatment of newly diagnosed glioblastoma patients does not alter patterns of progression. ( Clément, PM; Eisele, AC; Eisele, G; Krex, D; Neyns, B; Nikkhah, G; Ochsenbein, A; Picard, M; Schlegel, U; Simon, M; Stupp, R; Tabatabai, G; Tonn, J; Weller, M; Wick, A; Wick, W, 2014)
"Surgery followed by radiotherapy and concomitant and adjuvant temozolomide is standard therapy in newly diagnosed glioblastoma multiforme (GBM)."5.19Neoadjuvant bevacizumab and irinotecan versus bevacizumab and temozolomide followed by concomitant chemoradiotherapy in newly diagnosed glioblastoma multiforme: A randomized phase II study. ( Ask, A; Costa, JC; Engelholm, S; Grunnet, K; Hansen, S; Hofland, KF; Kristiansen, C; Lassen, U; Muhic, A; Poulsen, HS; Schultz, HP; Sorensen, M; Thomsen, C, 2014)
"To assess the effect and toxicity of hypofractionated high-dose intensity modulated radiation therapy (IMRT) with concurrent and adjuvant temozolomide (TMZ) in 46 patients with newly diagnosed glioblastoma multiforme (GBM)."5.19Phase 2 trial of hypofractionated high-dose intensity modulated radiation therapy with concurrent and adjuvant temozolomide for newly diagnosed glioblastoma. ( Hara, R; Hasegawa, Y; Hatano, K; Iuchi, T; Kawasaki, K; Kodama, T; Sakaida, T; Yokoi, S, 2014)
"Standard therapy for newly diagnosed glioblastoma is radiotherapy plus temozolomide."5.19Bevacizumab plus radiotherapy-temozolomide for newly diagnosed glioblastoma. ( Abrey, L; Brandes, AA; Carpentier, AF; Cernea, D; Chinot, OL; Cloughesy, T; Henriksson, R; Hilton, M; Hoang-Xuan, K; Kavan, P; Mason, W; Nishikawa, R; Saran, F; Wick, W, 2014)
"Concurrent treatment with temozolomide and radiotherapy followed by maintenance temozolomide is the standard of care for patients with newly diagnosed glioblastoma."5.19A randomized trial of bevacizumab for newly diagnosed glioblastoma. ( Aldape, KD; Armstrong, TS; Blumenthal, DT; Brachman, DG; Brown, PD; Chakravarti, A; Colman, H; Curran, WJ; Dignam, JJ; Gilbert, MR; Jaeckle, KA; Jeraj, R; Mehta, MP; Pugh, S; Schiff, D; Stieber, VW; Sulman, EP; Tremont-Lukats, IW; Vogelbaum, MA; Wefel, JS; Werner-Wasik, M; Won, M, 2014)
"A phase II trial was performed to evaluate the efficacy of a dose-dense, 7 days on/7 days off schedule of temozolomide for patients with recurrent high-grade gliomas (HGG)."5.19Phase II trial of 7 days on/7 days off temozolmide for recurrent high-grade glioma. ( Berger, MS; Butowski, NA; Chang, SM; Clarke, JL; DeSilva, A; Han, SJ; Molinaro, AM; Prados, MD; Rolston, JD, 2014)
"Prognosis of unresectable glioblastoma (GB) remains poor, despite temozolomide (TMZ)-based chemoradiation."5.19Randomized phase II trial of irinotecan and bevacizumab as neo-adjuvant and adjuvant to temozolomide-based chemoradiation compared with temozolomide-chemoradiation for unresectable glioblastoma: final results of the TEMAVIR study from ANOCEF†. ( Bonnetain, F; Campello, C; Castera, D; Chauffert, B; Chinot, O; Dalban, C; Durando, X; Fabbro, M; Feuvret, L; Frappaz, D; Frenay, M; Ghiringhelli, F; Guillamo, JS; Honnorat, J; Schott, R; Skrzypski, J; Taillandier, L; Taillia, H; Tennevet, I, 2014)
"We evaluated the prognostic and predictive value of a range of molecular changes in the setting of a randomised trial comparing standard PCV (procarbazine, CCNU (1-(2-chloroethyl)-3-cyclohexyl-1-nitrosourea) and vincristine) chemotherapy with the standard temozolomide (TMZ) 5-day (200 mg/m2/day) schedule and a 21-day (100 mg/m2/day) schedule in chemo-naïve, high-grade glioma (non-oligodendroglial tumours; WHO (World Health Organisation) grades III and IV) patients at first progression following radiotherapy."5.19Prognostic and predictive markers in recurrent high grade glioma; results from the BR12 randomised trial. ( Brada, M; Chan, R; Collins, VP; Di, Y; Gabe, R; Ichimura, K; Pearson, D; Stenning, SP; Thompson, LC, 2014)
"The objective of this study was to report the patterns of failure in patients with glioblastoma multiforme (GBM) treated on a phase II trial of hypofractionated intensity-modulated radiotherapy (hypo-IMRT) with concurrent and adjuvant temozolomide (TMZ)."5.19Hypofractionated intensity-modulated radiotherapy with temozolomide chemotherapy may alter the patterns of failure in patients with glioblastoma multiforme. ( Chen, C; Gaspar, LE; Kavanagh, BD; Reddy, K, 2014)
" The primary objective of this trial was to determine the maximum tolerated dose (MTD) and efficacy of HCQ in combination with radiation therapy (RT) and temozolomide (TMZ) for newly diagnosed glioblastoma (GB)."5.19A phase I/II trial of hydroxychloroquine in conjunction with radiation therapy and concurrent and adjuvant temozolomide in patients with newly diagnosed glioblastoma multiforme. ( Amaravadi, RK; Brem, S; Chang, YC; Davis, LE; Desideri, S; Fisher, J; Grossman, SA; Heitjan, DF; Hu, J; McAfee, Q; Mikkelson, T; O'Dwyer, PJ; Piao, S; Pontiggia, L; Rosenfeld, MR; Supko, JG; Tan, KS; Troxel, AB; Wang, D; Ye, X, 2014)
"Temozolomide (TMZ) may enhance antitumor immunity in patients with glioblastoma multiforme (GBM)."5.19Phase I/IIa trial of fractionated radiotherapy, temozolomide, and autologous formalin-fixed tumor vaccine for newly diagnosed glioblastoma. ( Abe, T; Hashimoto, K; Ikuta, S; Ishihara, T; Ishikawa, E; Karasawa, K; Maruyama, T; Matsuda, M; Matsumura, A; Matsutani, M; Muragaki, Y; Nakazato, Y; Ohno, T; Tsuboi, K; Uemae, Y; Yamamoto, T, 2014)
"Temozolomide (TMZ) is one of the most potent chemotherapy agents for the treatment of glioblastoma."5.19Gene therapy enhances chemotherapy tolerance and efficacy in glioblastoma patients. ( Adair, JE; Baldock, AL; Beard, BC; Born, DE; Bridge, CA; Gonzalez-Cuyar, LF; Gori, JL; Guyman, LA; Hawkins-Daarud, A; Johnston, SK; Kiem, HP; Mrugala, MM; Rockhill, JK; Rockne, RC; Silbergeld, DL; Storer, BE; Swanson, KR, 2014)
" We conducted a phase II trial in newly diagnosed glioblastoma utilizing a novel hypofractionated stereotactic radiotherapy (HFSRT) schedule combined with temozolomide and bevacizumab."5.19Phase II study of bevacizumab, temozolomide, and hypofractionated stereotactic radiotherapy for newly diagnosed glioblastoma. ( Abrey, LE; Barradas-Panchal, R; Baser, RE; Beal, K; Brennan, CW; Chan, TA; Correa, DD; DeAngelis, LM; Faivre, G; Gavrilovic, IT; Grommes, C; Gutin, P; Hormigo, A; Huse, JT; Kaley, TJ; Karimi, S; Lassman, AB; Mellinghoff, I; Nolan, C; Omuro, A; Panageas, KS; Pentsova, E; Reiner, AS; Sanchez, J; Tabar, V; Zhang, J, 2014)
" Data from phase 2 trials suggest that it has antitumour activity as a single agent in recurrent glioblastoma and in combination with standard temozolomide chemoradiotherapy in newly diagnosed glioblastoma (particularly in tumours with methylated MGMT promoter)."5.19Cilengitide combined with standard treatment for patients with newly diagnosed glioblastoma with methylated MGMT promoter (CENTRIC EORTC 26071-22072 study): a multicentre, randomised, open-label, phase 3 trial. ( Adamska, K; Aldape, KD; Brandes, AA; Erridge, SC; Gorlia, T; Grujicic, D; Gupta, T; Hau, P; Hegi, ME; Herrlinger, U; Hicking, C; Hong, YK; Kim, CY; Kortmann, RD; Lhermitte, B; Markivskyy, A; McBain, C; Nabors, LB; Nam, DH; Perry, J; Picard, M; Pietsch, T; Rao, N; Reardon, DA; Schnell, O; Shen, CC; Steinbach, JP; Stupp, R; Taphoorn, MJ; Tarnawski, R; Thurzo, L; Tonn, JC; van den Bent, MJ; Weller, M; Weyerbrock, A; Wick, W; Wiegel, T, 2014)
"We investigate the patterns of failure in the treatment of glioblastoma (GBM) based on clinical target volume (CTV) margin size, dose delivered to the site of initial failure, and the use of temozolomide and intensity-modulated radiotherapy (IMRT)."5.19Limited margins using modern radiotherapy techniques does not increase marginal failure rate of glioblastoma. ( Chan, MD; Debinski, W; Ellis, TL; Hinson, WH; Johnson, AJ; Kearns, WT; Lesser, GJ; McMullen, KP; Paulsson, AK; Peiffer, AM; Shaw, EG; Tatter, SB, 2014)
" The primary objective of this study was to determine the safety of the combination of PPX with temozolomide and concurrent radiation for high-grade gliomas."5.19Paclitaxel poliglumex, temozolomide, and radiation for newly diagnosed high-grade glioma: a Brown University Oncology Group Study. ( Boxerman, J; Cielo, D; Constantinou, M; Dipetrillo, T; Donahue, J; Elinzano, H; Evans, D; Goldman, M; Isdale, D; Jeyapalan, S; Kinsella, T; Mantripragada, K; Oyelese, A; Puthawala, Y; Rosati, K; Safran, H; Santaniello, A; Stopa, E, 2014)
"To determine the safety and efficacy of hypofractionated intensity modulated radiation therapy (Hypo-IMRT) using helical tomotherapy (HT) with concurrent low dose temozolomide (TMZ) followed by adjuvant TMZ in patients with glioblastoma multiforme (GBM)."5.17Phase I study of hypofractionated intensity modulated radiation therapy with concurrent and adjuvant temozolomide in patients with glioblastoma multiforme. ( Abdulkarim, B; Fallone, G; Field, C; Fulton, D; Ghosh, S; Jastaniyah, N; Le, D; Mackenzie, M; Murtha, A; Patel, S; Pervez, N; Roa, W, 2013)
"A multicenter, two stage phase II study, investigated irinotecan plus temozolomide in children with newly diagnosed high grade glioma."5.17A phase II single-arm study of irinotecan in combination with temozolomide (TEMIRI) in children with newly diagnosed high grade glioma: a joint ITCC and SIOPE-brain tumour study. ( Ashley, D; Breazna, A; Cisar, L; Clausen, N; Cruz-Martinez, O; Dorman, A; Elliott, M; English, M; Frappaz, D; Fuster, JL; Geoerger, B; Gesner, L; Grill, J; Hargrave, D; Icher, C; Leblond, P; Perilongo, G; Pietsch, T; Rialland, X, 2013)
"The alkylating agent temozolomide (TMZ) is widely used for the treatment of gliomas."5.17Secondary hematological malignancies associated with temozolomide in patients with glioma. ( Miyakita, Y; Momota, H; Narita, Y; Shibui, S, 2013)
"Among patients with glioblastoma (GBM) who progress on standard temozolomide, the optimal therapy is unknown."5.17Phase 2 study of dose-intense temozolomide in recurrent glioblastoma. ( Batchelor, TT; Beroukhim, R; Doherty, L; Drappatz, J; Fadul, CE; Hammond, SN; Lafrankie, D; Lee, EQ; Lesser, GJ; Ligon, KL; Lis, R; Muzikansky, A; Norden, AD; Plotkin, SR; Reardon, DR; Rosenfeld, MR; Smith, K; Stack, EC; Tafoya, V; Wen, PY; Zhu, JJ, 2013)
"To describe the quality of life (QOL) in elderly patients with glioblastoma (GBM) treated with an abbreviated course of radiation therapy (RT; 40 Gy in 15 fractions) plus concomitant and adjuvant temozolomide (TMZ)."5.17Health-related quality of life in elderly patients with newly diagnosed glioblastoma treated with short-course radiation therapy plus concomitant and adjuvant temozolomide. ( Baldoni, A; De Sanctis, V; Enrici, RM; Esposito, V; Lanzetta, G; Minniti, G; Scaringi, C, 2013)
"Thirteen patients with recurrent glioblastoma were enrolled in RTOG 0625/ACRIN 6677, a prospective multicenter trial in which bevacizumab was used in combination with either temozolomide or irinotecan."5.17Magnetic resonance spectroscopy as an early indicator of response to anti-angiogenic therapy in patients with recurrent glioblastoma: RTOG 0625/ACRIN 6677. ( Barboriak, DP; Bokstein, F; Boxerman, JL; Gilbert, MR; McKinstry, RC; Ratai, EM; Safriel, Y; Snyder, BS; Sorensen, AG; Zhang, Z, 2013)
"The prognostic role of O(6)-methylguanine-DNA methyltransferase (MGMT) promoter methylation in glioblastoma patients treated with carmustine (BCNU) wafer implantation is unclear."5.17MGMT promoter methylation status and prognosis of patients with primary or recurrent glioblastoma treated with carmustine wafers. ( Bock, HC; Brück, W; Doerner, L; Felsberg, J; Giese, A; Gutenberg, A; Mehdorn, HM; Reifenberger, G; Roggendorf, W; Westphal, M, 2013)
"To determine the safety of the mammalian target of rapamycin inhibitor everolimus (RAD001) administered daily with concurrent radiation and temozolomide in newly diagnosed glioblastoma patients."5.17RTOG 0913: a phase 1 study of daily everolimus (RAD001) in combination with radiation therapy and temozolomide in patients with newly diagnosed glioblastoma. ( Chinnaiyan, P; Corn, BW; Dipetrillo, TA; Mehta, MP; Rojiani, AM; Wen, PY; Wendland, M; Won, M, 2013)
"To report health-related quality of life (HRQOL) in glioblastoma (GBM) patients treated on a phase II trial of hypofractionated intensity-modulated radiotherapy (hypo-IMRT) with temozolomide (TMZ)."5.17Prospective evaluation of health-related quality of life in patients with glioblastoma multiforme treated on a phase II trial of hypofractionated IMRT with temozolomide. ( Chen, C; Damek, DM; Gaspar, LE; Kavanagh, BD; Lillehei, KO; Ney, D; Reddy, K; Waziri, A, 2013)
"RTOG 0625/ACRIN 6677 is a multicenter, randomized, phase II trial of bevacizumab with irinotecan or temozolomide in recurrent glioblastoma (GBM)."5.17Early post-bevacizumab progression on contrast-enhanced MRI as a prognostic marker for overall survival in recurrent glioblastoma: results from the ACRIN 6677/RTOG 0625 Central Reader Study. ( Barboriak, DP; Boxerman, JL; Chi, TL; Gilbert, MR; Jain, R; Larvie, M; Safriel, Y; Snyder, BS; Sorensen, AG; Zhang, Z, 2013)
"The current standard-of-care for glioblastoma (GBM) is represented by concomitant radiotherapy (RT) and temozolomide (TMZ), according to Stupp's protocol."5.17Continuous tamoxifen and dose-dense temozolomide in recurrent glioblastoma. ( Caroli, M; Carrabba, G; DI Cristofori, A; Lanfranchi, G; Menghetti, C; Rampini, P, 2013)
"To investigate the impact of nonstandard concomitant temozolomide (TMZ) administration in two prospective phase II studies for glioblastoma (GBM)."5.17Concurrent and adjuvant temozolomide-based chemoradiotherapy schedules for glioblastoma. Hypotheses based on two prospective phase II trials. ( Alitto, AR; Anile, C; Balducci, M; Chiesa, S; Colosimo, C; D'Agostino, GR; De Bonis, P; Fiorentino, A; Frascino, V; Mangiola, A; Mantini, G; Mattiucci, GC; Valentini, V, 2013)
"Radiotherapy with concomitant and adjuvant temozolomide is the standard of care for newly diagnosed glioblastoma (GBM)."5.17Dose-dense temozolomide for newly diagnosed glioblastoma: a randomized phase III clinical trial. ( Aldape, KD; Armstrong, TS; Baumert, B; Blumenthal, DT; Brown, PD; Chakravarti, A; Curran, WJ; Erridge, S; Gilbert, MR; Hegi, ME; Hopkins, KI; Jaeckle, KA; Mahajan, A; Mehta, MP; Schultz, CJ; Stupp, R; Tzuk-Shina, T; Wang, M; Wefel, JS; Won, M, 2013)
"Radiation Therapy Oncology Group trial 0525 tested whether dose-intensifying temozolomide versus standard chemoradiotherapy improves overall survival (OS) or progression-free survival (PFS) in newly diagnosed glioblastoma."5.17Net clinical benefit analysis of radiation therapy oncology group 0525: a phase III trial comparing conventional adjuvant temozolomide with dose-intensive temozolomide in patients with newly diagnosed glioblastoma. ( Armstrong, TS; Bottomley, A; Brachman, DG; Choucair, AK; Coens, C; Gilbert, MR; Mehta, M; Mendoza, TR; Wang, M; Wefel, JS; Werner-Wasik, M; Won, M, 2013)
" Multiple glioma cell lines were analyzed for viability after treatment with radiation, temozolomide, or sorafenib or combinations of them."5.17A phase I study of the combination of sorafenib with temozolomide and radiation therapy for the treatment of primary and recurrent high-grade gliomas. ( Andrews, DW; Camphausen, K; Den, RB; Dicker, AP; Dougherty, E; Friedman, DP; Glass, J; Green, MR; Hegarty, S; Hyslop, T; Kamrava, M; Lawrence, YR; Marinucchi, M; Sheng, Z; Werner-Wasik, M, 2013)
"We performed a dose-escalation trial to determine the maximum tolerated dose (MTD) of intensity-modulated radiotherapy (IMRT) with standard concurrent and sequential-dose temozolomide (TMZ) in patients with glioblastoma multiforme."5.17Accelerated intensity-modulated radiotherapy plus temozolomide in patients with glioblastoma: a phase I dose-escalation study (ISIDE-BT-1). ( Balducci, M; Cilla, S; Deodato, F; Ferro, M; Macchia, G; Massaccesi, M; Morganti, AG; Valentini, V, 2013)
"In this phase II trial, we investigated the efficacy of a metronomic temozolomide schedule in the treatment of recurrent malignant gliomas (MGs)."5.17Phase II trial of continuous low-dose temozolomide for patients with recurrent malignant glioma. ( Abrey, LE; Chan, TA; Deangelis, LM; Gavrilovic, IT; Heguy, A; Hormigo, A; Hottinger, AF; Huse, JT; Kaley, TJ; Kaufman, A; Khasraw, M; Lassman, AB; Mellinghoff, I; Nolan, CP; Omuro, A; Panageas, KS; Reiner, AS; Salvant, C, 2013)
"We undertook this phase I study to investigate the feasibility of the combination of temozolomide (TMZ) and lapatinib (LP) and to define the maximum tolerated dose (MTD) of LP in patients with relapsed high-grade gliomas."5.17A phase I study of temozolomide and lapatinib combination in patients with recurrent high-grade gliomas. ( Bobos, M; Chrisafi, S; Fountzilas, G; Karavasilis, V; Kotoula, V; Lambaki, S; Pentheroudakis, G; Televantou, D, 2013)
"To evaluate in a single center retrospectively the efficacy and tolerability of a weekly regimen, which alternates temozolomide (TMZ) in patients with recurrent or progressive high-grade glioma (HGG)."5.17"One week on-one week off": efficacy and side effects of dose-intensified temozolomide chemotherapy: experiences of a single center. ( Berhorn, T; Blau, T; Dunkl, V; Fink, GR; Galldiks, N; Schroeter, M, 2013)
"Locoregional chemotherapy with carmustine wafers, positioned at surgery and followed by radiation therapy, has been shown to prolong survival in patients with newly diagnosed glioblastoma, as has concomitant radiochemotherapy with temozolomide."5.17Prospective study of carmustine wafers in combination with 6-month metronomic temozolomide and radiation therapy in newly diagnosed glioblastoma: preliminary results. ( Casali, C; Ciusani, E; Dimeco, F; Fariselli, L; Gaviani, P; Guzzetti, S; Maccagnano, C; Marchetti, M; Milanesi, I; Pollo, B; Salmaggi, A; Silvani, A; Solero, CL, 2013)
"To determine the safety of the addition of bevacizumab to standard radiation therapy and daily temozolomide for newly diagnosed glioblastoma multiforme (GBM)."5.16Addition of bevacizumab to standard radiation therapy and daily temozolomide is associated with minimal toxicity in newly diagnosed glioblastoma multiforme. ( Bailey, L; Desjardins, A; Friedman, A; Friedman, HS; Herndon, JE; Kirkpatrick, JP; Marcello, J; Peters, KB; Reardon, DA; Sampson, J; Threatt, S; Vredenburgh, JJ, 2012)
"The new standard treatment of glioblastoma multiforme is concurrent radiotherapy (RT) and temozolomide."5.16Phase I clinical trial assessing temozolomide and tamoxifen with concomitant radiotherapy for treatment of high-grade glioma. ( Amin, P; Cheston, S; Dhople, A; DiBiase, S; Flannery, T; Meisenberg, B; Patel, A; Patel, S, 2012)
"This paper aims to study the value of MRI and Thallium 201 ((201)Tl) single-photon emission computed tomography (SPECT) in the prediction of overall survival (OS) in glioma patients treated with temozolomide (TMZ) and to evaluate timing of radiological follow-up."5.16MRI and thallium-201 SPECT in the prediction of survival in glioma. ( Berkhof, J; Bosma, I; Buter, J; Heimans, JJ; Hoekstra, OS; Lagerwaard, FJ; Noske, DP; Postma, TJ; Reijneveld, JC; Sanchez, E; Sizoo, EM; Vos, MJ, 2012)
"The authors performed a phase 2 trial of combined protracted daily temozolomide and biweekly bevacizumab for patients with recurrent glioblastoma who had previously received radiation therapy and temozolomide."5.16Bevacizumab and daily temozolomide for recurrent glioblastoma. ( Bailey, L; Coan, A; Desjardins, A; Friedman, HS; Herndon, JE; Marcello, J; Peters, KB; Reardon, DA; Vredenburgh, JJ, 2012)
"Patients with high-grade glioma can be treated with carmustine wafers or following the Stupp protocol."5.16Prognostic factors and survival in a prospective cohort of patients with high-grade glioma treated with carmustine wafers or temozolomide on an intention-to-treat basis. ( Aurrecoechea-Obieta, J; Bilbao-Barandica, G; Canales-Llantada, M; Carbayo-Lozano, G; Catalán-Uribarrena, G; Galbarriatu-Gutiérrez, L; Igartua-Azkune, A; Pomposo-Gaztelu, I; Ruiz de Gopegui-Ruiz, E; Undabeitia-Huertas, J, 2012)
"This phase I trial was designed to determine the recommended phase II dose(s) of everolimus (RAD001) with temozolomide (TMZ) in patients with glioblastoma (GBM)."5.16A phase I study of temozolomide and everolimus (RAD001) in patients with newly diagnosed and progressive glioblastoma either receiving or not receiving enzyme-inducing anticonvulsants: an NCIC CTG study. ( Easaw, J; Eisenhauer, E; Kavan, P; Lwin, Z; Macdonald, D; Macneil, M; Mason, WP; McIntosh, L; Thiessen, B; Urva, S, 2012)
"To compare the therapeutic efficacy of two regimens of postoperative radiotherapy with concurrent chemotherapy using temozolomide (TMZ) and teniposide (VM-26) plus semustine (Me-CCNU) in adult patients with grade III-IV cerebral gliomas."5.16[Comparison of two regimens of postoperative concurrent chemoradiotherapy in adult patients with grade III-IV cerebral gliomas]. ( Gu, K; Wang, J; Zhai, X; Zhang, J, 2012)
"To report toxicity and overall survival (OS) in patients with newly diagnosed glioblastoma multiforme (GBM) treated with hypofractionated intensity-modulated radiotherapy (hypo-IMRT) with concurrent and adjuvant temozolomide (TMZ)."5.16Phase II trial of hypofractionated IMRT with temozolomide for patients with newly diagnosed glioblastoma multiforme. ( Chen, C; Damek, D; Gaspar, LE; Kavanagh, BD; Lillehei, K; Ney, D; Reddy, K; Stuhr, K; Waziri, A, 2012)
" The primary objectives of this randomized phase 2 trial were to determine the safety and efficacy of cilengitide when combined with radiation and temozolomide for patients with newly diagnosed glioblastoma multiforme and to select a dose for comparative clinical testing."5.16A safety run-in and randomized phase 2 study of cilengitide combined with chemoradiation for newly diagnosed glioblastoma (NABTT 0306). ( Batchelor, T; Brem, S; Fisher, JD; Grossman, SA; Hegi, ME; Lesser, G; Mikkelsen, T; Nabors, LB; Olsen, J; Peereboom, D; Rosenfeld, MR; Ye, X, 2012)
"4 Gy radiotherapy with up-front temozolomide in previously untreated low-grade glioma."5.16Quality assurance in the EORTC 22033-26033/CE5 phase III randomized trial for low grade glioma: the digital individual case review. ( Bar-Deroma, R; Baumert, BG; Fairchild, A; Fenton, PA; Gulyban, A; Stupp, R; Weber, DC, 2012)
" We did a randomised trial to compare the efficacy and safety of dose-dense temozolomide alone versus radiotherapy alone in elderly patients with anaplastic astrocytoma or glioblastoma."5.16Temozolomide chemotherapy alone versus radiotherapy alone for malignant astrocytoma in the elderly: the NOA-08 randomised, phase 3 trial. ( Braun, C; Combs, SE; Felsberg, J; Ketter, R; Mayer-Steinacker, R; Meisner, C; Meixensberger, J; Nikkhah, G; Papsdorf, K; Platten, M; Reifenberger, G; Sabel, M; Simon, M; Steinbach, JP; Tabatabai, G; Vesper, J; Weller, M; Wick, W, 2012)
"To evaluate the efficacy of adding bevacizumab, a vascular endothelial growth factor (VEGF) inhibitor, and everolimus, a mammalian target of rapamycin (mTOR inhibitor), to standard radiation therapy/temozolomide in the first-line treatment of patients with glioblastoma."5.16Phase II study of concurrent radiation therapy, temozolomide, and bevacizumab followed by bevacizumab/everolimus as first-line treatment for patients with glioblastoma. ( Brinker, BT; Hainsworth, JD; Shepard, GC; Shih, KC; Spigel, DR; Tillinghast, GW, 2012)
"To evaluate the toxicity and maximum tolerated dose (MTD) of arsenic trioxide (ATO) in combination with temozolomide (TMZ) and radiation therapy (RT) in malignant gliomas."5.16Phase I study of arsenic trioxide and temozolomide in combination with radiation therapy in patients with malignant gliomas. ( Chandler, JP; Grimm, SA; Jovanovic, B; Levy, RM; Marymont, M; McCarthy, K; Muro, K; Newman, SB; Raizer, JJ, 2012)
" Both temozolomide and hypofractionated radiotherapy should be considered as standard treatment options in elderly patients with glioblastoma."5.16Temozolomide versus standard 6-week radiotherapy versus hypofractionated radiotherapy in patients older than 60 years with glioblastoma: the Nordic randomised, phase 3 trial. ( Abacioglu, U; Frappaz, D; Grønberg, BH; Hegi, ME; Henriksson, R; Lhermitte, B; Malmström, A; Marosi, C; Rosell, J; Schultz, H; Stupp, R; Tavelin, B, 2012)
"The assessment of the therapeutic response of high-grade gliomas treated with concomitant chemoradiotherapy (CCRT) using temozolomide is difficult because of the frequent occurrence of early imaging changes that are indistinguishable from tumor progression, termed pseudoprogression."5.16Diffusion-weighted MR imaging for the differentiation of true progression from pseudoprogression following concomitant radiotherapy with temozolomide in patients with newly diagnosed high-grade gliomas. ( Choi, SH; Kim, IH; Kim, JH; Kim, TM; Lee, SH; Lee, WJ; Park, CK; Park, SH; Sohn, CH; Yi, KS, 2012)
"A phase I, dose-finding study of vorinostat in combination with temozolomide (TMZ) was conducted to determine the maximum tolerated dose (MTD), safety, and pharmacokinetics in patients with high-grade glioma (HGG)."5.16Phase I study of vorinostat in combination with temozolomide in patients with high-grade gliomas: North American Brain Tumor Consortium Study 04-03. ( Ames, MM; Chang, SM; Cloughesy, TF; Desideri, S; Drappatz, J; Espinoza-Delgado, I; Gilbert, MR; Kuhn, JG; Lamborn, KR; Lassman, AB; Lee, EQ; Lieberman, FS; McGovern, RM; Prados, MD; Puduvalli, VK; Reid, JM; Robins, HI; Wen, PY; Xu, J; Ye, X; Yung, WK, 2012)
"To determine whether the pattern of progressive disease (PD) for glioblastoma multiforme (GBM) patients has changed with the introduction of the current standard of care protocol - postoperative conformal radiotherapy to a dose of 60 Gray in 30 fractions with concurrent low-dose (75-100 mg/m(2) ) temozolomide, followed by six cycles of adjuvant high-dose (150-200 mg/m(2) ) temozolomide - as compared with radiotherapy alone."5.16The addition of temozolomide does not change the pattern of progression of glioblastoma multiforme post-radiotherapy. ( Bressel, M; Gunjur, A; Ryan, G, 2012)
"In the present study we investigated the feasibility and effectiveness of a new biweekly schedule of fotemustine (FTM) in patients with recurrent glioblastoma, after at least one previous treatment."5.15A new schedule of fotemustine in temozolomide-pretreated patients with relapsing glioblastoma. ( Abbruzzese, A; Addeo, R; Caraglia, M; Carraturo, M; Cennamo, G; De Santi, MS; Del Prete, S; Faiola, V; Genovese, M; Montella, L; Parlato, C; Vincenzi, B, 2011)
"We evaluated the efficacy of metronomic etoposide or temozolomide administered with bevacizumab among recurrent glioblastoma (GBM) patients who progressed on prior bevacizumab therapy in a phase 2, open-label, two-arm trial."5.15Phase II study of metronomic chemotherapy with bevacizumab for recurrent glioblastoma after progression on bevacizumab therapy. ( Desjardins, A; Friedman, AH; Friedman, HS; Gururangan, S; Herndon, JE; Marcello, J; McLendon, R; Peters, K; Reardon, DA; Rich, JN; Sampson, J; Threatt, S; Vredenburgh, JJ, 2011)
"To determine the maximal tolerated biologic dose intensification of radiotherapy using fractional dose escalation with temozolomide (TMZ) chemotherapy in patients with newly diagnosed glioblastoma multiforme."5.15Phase I trial of hypofractionated intensity-modulated radiotherapy with temozolomide chemotherapy for patients with newly diagnosed glioblastoma multiforme. ( Chen, C; Damek, D; Gaspar, LE; Kavanagh, BD; Kleinschmidt-DeMasters, BK; Lillehei, K; Robischon, M; Rusthoven, KE; Stuhr, K; Waziri, A, 2011)
"To determine the maximum tolerated dose (MTD) of tipifarnib in combination with conventional radiotherapy for patients with newly diagnosed glioblastoma."5.15A phase I trial of tipifarnib with radiation therapy, with and without temozolomide, for patients with newly diagnosed glioblastoma. ( Abrey, L; Chang, SM; Cloughesy, TF; DeAngelis, LM; Demopoulos, A; Drappatz, J; Fine, HA; Fink, K; Kesari, S; Lamborn, KR; Lassman, AB; Lieberman, FS; Malkin, MG; Mehta, MP; Nghiemphu, PL; Prados, MD; Robins, HI; Torres-Trejo, A; Wen, PY, 2011)
"This open-label, prospective, multicenter single-arm phase II study combined bevacizumab (BV) with radiation therapy (RT) and temozolomide (TMZ) for the treatment of newly diagnosed glioblastoma (GBM)."5.15Phase II study of bevacizumab plus temozolomide during and after radiation therapy for patients with newly diagnosed glioblastoma multiforme. ( Black, K; Cloughesy, T; Elashoff, R; Fehrenbacher, L; Filka, E; Green, RM; Kolevska, T; Lai, A; Liau, LM; Mischel, PS; Nghiemphu, PL; Peak, S; Phuphanich, S; Polikoff, J; Pope, WB; Selch, M; Solis, OE; Spier, CE; Tran, A; Yong, WH, 2011)
"The objective of this prospective, monocentric phase-II pilot study was to evaluate toxicity and efficacy of neoadjuvant temozolomide (TMZ) and 13-cis retinoic acid (13-cRA) treatment in patients with newly diagnosed anaplastic gliomas after total or subtotal tumor resection."5.15Temozolomide and 13-cis retinoic acid in patients with anaplastic gliomas: a prospective single-arm monocentric phase-II study (RNOP-05). ( Bogdahn, U; Brawanski, A; Grauer, O; Hartmann, C; Hau, P; Pascher, C; Pietsch, T; Proescholdt, M; Weller, M; Wick, W; Zeman, F, 2011)
"To analyse patterns of failure in patients with glioblastoma multiforme treated with concurrent radiation and temozolomide."5.15Patterns of failure for glioblastoma multiforme following concurrent radiation and temozolomide. ( Burnett Iii, OL; Dobelbower, MC; Fiveash, JB; Hyatt, MD; Markert, JM; Nabors, LB; Nordal, RA, 2011)
"The quantitative expression of CD133 stem cell antigen mRNA using real-time QRT-PCR was assessed in a cohort of 48 consecutive primary glioblastoma patients treated by chemoradiation with temozolomide."5.15Prognostic impact of CD133 mRNA expression in 48 glioblastoma patients treated with concomitant radiochemotherapy: a prospective patient cohort at a single institution. ( Barrie, M; Chinot, O; Colin, C; Coulibaly, B; Delfino, C; Figarella-Branger, D; Fina, F; Loundou, A; Metellus, P; Nanni-Metellus, I; Ouafik, L; Tchogandjian, A, 2011)
"Forty-two patients with glioblastoma and 16 patients with anaplastic glioma who had received concurrent radiation and temozolomide and adjuvant temozolomide were enrolled at first relapse."5.15Phase II study of aflibercept in recurrent malignant glioma: a North American Brain Tumor Consortium study. ( Aldape, K; Chang, SM; Chen, A; Cloughesy, TF; de Groot, JF; Deangelis, LM; Gilbert, MR; Jackson, EF; Lamborn, KR; Lassman, AB; Lieberman, F; Mehta, MP; Prados, MD; Robins, HI; Wen, PY; Yao, J; Yung, WK, 2011)
"This study compared the central nervous system (CNS) metastasis incidence between a temozolomide- and a dacarbazine-based regimen in untreated stage IV melanoma patients."5.15Central nervous system failure in melanoma patients: results of a randomised, multicentre phase 3 study of temozolomide- and dacarbazine- based regimens. ( Brugnara, S; Chiarion-Sileni, V; Colucci, G; De Salvo, GL; Del Bianco, P; Guida, M; Pigozzo, J; Ridolfi, L; Ridolfi, R; Romanini, A, 2011)
" We report that the lymphopenia induced by the chemotherapeutic agent temozolomide (TMZ) enhances vaccine-driven immune responses and significantly reduces malignant growth in an established model of murine tumorigenesis."5.15Monoclonal antibody blockade of IL-2 receptor α during lymphopenia selectively depletes regulatory T cells in mice and humans. ( Archer, GE; Bigner, DD; Congdon, KL; Cui, X; Desjardins, A; Friedman, AH; Friedman, HS; Herndon, JE; McLendon, RE; Mitchell, DA; Reardon, DA; Sampson, JH; Sanchez-Perez, L; Schmittling, RJ; Snyder, DJ; Vredenburgh, JJ, 2011)
"Concurrent and post-radiotherapy temozolomide (T) significantly improves survival in patient with newly diagnosed glioblastoma multiforme."5.15Phase 2 trial of temozolomide and pegylated liposomal doxorubicin in the treatment of patients with glioblastoma multiforme following concurrent radiotherapy and chemotherapy. ( Ananda, S; Brown, C; Cher, L; Dowling, A; Nowak, AK; Rosenthal, MA; Simes, J, 2011)
"Patients with newly diagnosed malignant glioma received AdV-tk at 3 × 10(10), 1 × 10(11), or 3 × 10(11) vector particles (vp) via tumor bed injection at time of surgery followed by 14 days of valacyclovir."5.15Phase IB study of gene-mediated cytotoxic immunotherapy adjuvant to up-front surgery and intensive timing radiation for malignant glioma. ( Aguilar, LK; Aguilar-Cordova, E; Baskin, DS; Bell, SD; Cavaliere, R; Chakravarti, A; Chiocca, EA; Grecula, J; Grossman, RG; Hardcastle, J; Harris, KS; Kaur, B; Lo, S; Manzanera, AG; McGregor, J; Monterroso, C; New, PZ; Newton, H; Ray-Chaudhuri, A; Trask, TW, 2011)
"This analysis was performed to assess whether antiepileptic drugs (AEDs) modulate the effectiveness of temozolomide radiochemotherapy in patients with newly diagnosed glioblastoma."5.15Prolonged survival with valproic acid use in the EORTC/NCIC temozolomide trial for glioblastoma. ( Belanger, K; Bogdahn, U; Brandes, AA; Cairncross, JG; Forsyth, P; Gorlia, T; Lacombe, D; Macdonald, DR; Mason, W; Mirimanoff, RO; Rossetti, AO; Stupp, R; van den Bent, MJ; Vecht, CJ; Weller, M, 2011)
"This open-label, single-arm, phase II study combined enzastaurin with temozolomide plus radiation therapy (RT) to treat glioblastoma multiforme (GBM) and gliosarcoma."5.15Phase II and pharmacogenomics study of enzastaurin plus temozolomide during and following radiation therapy in patients with newly diagnosed glioblastoma multiforme and gliosarcoma. ( Butowski, N; Chang, SM; Clarke, J; Costa, BM; Costello, JF; Hristova-Kazmierski, M; Hsieh, E; Lamborn, KR; Nicol, SJ; Nicole, A; Parvataneni, R; Pieper, R; Polley, MY; Prados, MD; Reis, RM; Sneed, PK; Thornton, DE; Vandenberg, S, 2011)
"The primary objectives of this phase II study were to evaluate the use of preirradiation temozolomide followed by concurrent temozolomide and radiotherapy (RT) in patients with newly diagnosed anaplastic oligodendroglioma (AO) and mixed anaplastic oligoastrocytoma (MOA)."5.14Phase II trial of preirradiation and concurrent temozolomide in patients with newly diagnosed anaplastic oligodendrogliomas and mixed anaplastic oligoastrocytomas: RTOG BR0131. ( Berkey, B; Biggs, C; Blumenthal, DT; Brown, P; Giannini, C; Herman, J; Jenkins, R; Macdonald, D; Mehta, M; Peereboom, D; Schultz, C; Suh, JH; Vogelbaum, MA, 2009)
"To determine whether increased uptake on 11C-methionine-PET (MET-PET) imaging obtained before radiation therapy and temozolomide is associated with the site of subsequent failure in newly diagnosed glioblastoma multiforme (GBM)."5.14Association of 11C-methionine PET uptake with site of failure after concurrent temozolomide and radiation for primary glioblastoma multiforme. ( Cao, Y; Gomez-Hassan, D; Hayman, J; Junck, L; Lawrence, TS; Lee, IH; Piert, M; Rogers, L; Ten Haken, RK; Tsien, C, 2009)
"In a search for more effective combination chemotherapy for the treatment of metastatic melanoma, we conducted a phase I trial of a novel combination of docetaxel, temozolomide, and cisplatin."5.14Phase I study of the combination of docetaxel, temozolomide and cisplatin in patients with metastatic melanoma. ( Bedikian, AY; Camacho, LH; Frost, AM; Hernandez, IM; Hwu, P; Hwu, WJ; Jack, MA; Kim, KB; Ng, C; Papadopoulos, NE, 2009)
"This open-label, prospective, single-arm, phase II study combined erlotinib with radiation therapy (XRT) and temozolomide to treat glioblastoma multiforme (GBM) and gliosarcoma."5.14Phase II study of erlotinib plus temozolomide during and after radiation therapy in patients with newly diagnosed glioblastoma multiforme or gliosarcoma. ( Ayers-Ringler, J; Berger, MS; Butowski, N; Carliner, H; Chang, SM; DeBoer, R; Fedoroff, A; Haas-Kogan, DA; James, CD; Kabuubi, P; Lamborn, KR; McDermott, MW; Page, M; Parsa, AT; Parvataneni, R; Prados, MD; Rabbitt, J; Sneed, PK; Stokoe, D; Vandenberg, S, 2009)
"Patients with newly diagnosed oligodendroglioma or oligoastrocytoma with a MIB-1 index of >5% or recurrent low-grade gliomas received temozolomide (75 mg/m(2)/day in 11-week cycles of 7 weeks on/4 weeks off)."5.14Phase II study of protracted daily temozolomide for low-grade gliomas in adults. ( Black, PM; Bradshaw, J; Ciampa, A; Doherty, L; Drappatz, J; Kesari, S; LaFrankie, D; Levy, B; Ligon, KL; Macklin, EA; Muzikansky, A; Norden, AD; Radakovic, G; Ramakrishna, N; Santagata, S; Schiff, D; Wen, PY, 2009)
"Standardized salvage treatment has not yet proved effective in glioblastoma multiforme (GBM) patients who receive prior standard radiotherapy plus concomitant and adjuvant temozolomide."5.14Fotemustine as second-line treatment for recurrent or progressive glioblastoma after concomitant and/or adjuvant temozolomide: a phase II trial of Gruppo Italiano Cooperativo di Neuro-Oncologia (GICNO). ( Amistà, P; Bianchini, C; Blatt, V; Brandes, AA; Ermani, M; Faedi, M; Franceschi, E; Gardiman, M; Labianca, R; Reni, M; Santoro, A; Tosoni, A, 2009)
"This phase II trial was designed to define the role of O(6)-benzylguanine (O(6)-BG) in restoring temozolomide sensitivity in patients with recurrent or progressive, temozolomide-resistant malignant glioma and to evaluate the safety of administering O(6)-BG in combination with temozolomide."5.14Phase II trial of temozolomide plus o6-benzylguanine in adults with recurrent, temozolomide-resistant malignant glioma. ( Bigner, DD; Desjardins, A; Friedman, AH; Friedman, HS; Gururangan, S; Herndon, JE; Jiang, SX; McLendon, RE; Quinn, JA; Reardon, DA; Rich, JN; Sampson, JH; Vredenburgh, JJ; Walker, A, 2009)
"In 2004, a randomised phase III trial by the European Organisation for Research and Treatment of Cancer (EORTC) and National Cancer Institute of Canada Clinical Trials Group (NCIC) reported improved median and 2-year survival for patients with glioblastoma treated with concomitant and adjuvant temozolomide and radiotherapy."5.14Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial. ( Allgeier, A; Belanger, K; Brandes, AA; Cairncross, JG; Eisenhauer, E; Fisher, B; Gijtenbeek, J; Gorlia, T; Hau, P; Hegi, ME; Janzer, RC; Lacombe, D; Ludwin, SK; Marosi, C; Mason, WP; Mirimanoff, RO; Mokhtari, K; Stupp, R; Taphoorn, MJ; van den Bent, MJ; Vecht, CJ; Villa, S; Weller, M; Wesseling, P, 2009)
"This phase I clinical trial conducted with patients who had recurrent or progressive malignant glioma (MG) was designed to determine the maximum tolerated dose (MTD) and toxicity of three different 5-day dosing regimens of temozolomide (TMZ) in combination with O(6)-benzylguanine (O(6)-BG)."5.14Phase I trial of temozolomide plus O6-benzylguanine 5-day regimen with recurrent malignant glioma. ( Bigner, DD; Desjardins, A; Friedman, AH; Friedman, HS; Gururangan, S; Herndon, JE; Jiang, SX; McLendon, RE; Quinn, JA; Reardon, DA; Rich, JN; Sampson, JH; Vredenburgh, JJ; Walker, A, 2009)
" We investigated the time course of tumor metabolism in low-grade gliomas (LGG) during temozolomide chemotherapy, and compared metabolic responses as measured with positron emission tomography (PET) with volume responses as revealed by magnetic resonance imaging (MR)."5.14Early metabolic responses in temozolomide treated low-grade glioma patients. ( Bärtschi, E; Bruehlmeier, M; Buettner, UW; Hefti, M; Hofer, S; Roelcke, U; Uhlmann, C; Wyss, M, 2009)
"Alternative dosing schedules of temozolomide may improve survival in patients with newly diagnosed glioblastoma (GBM) by increasing the therapeutic index, overcoming common mechanisms of temozolomide resistance, or both."5.14Randomized phase II trial of chemoradiotherapy followed by either dose-dense or metronomic temozolomide for newly diagnosed glioblastoma. ( Abrey, LE; Clarke, JL; DeAngelis, LM; Gavrilovic, I; Hormigo, A; Iwamoto, FM; Karimi, S; Lassman, AB; Nolan, CP; Panageas, K; Sul, J, 2009)
"This phase II trial evaluated efficacy and safety of temozolomide (TMZ) in combination with irinotecan (CPT-11) before radiotherapy in patients with newly diagnosed glioblastoma multiforme (GBM)."5.14Phase II trial of temozolomide (TMZ) plus irinotecan (CPT-11) in adults with newly diagnosed glioblastoma multiforme before radiotherapy. ( Desjardins, A; Friedman, AH; Friedman, HS; Herndon, JE; Jiang, SX; McLendon, RE; Quinn, JA; Reardon, DA; Sampson, JH; Vredenburgh, JJ, 2009)
"This trial was designed to estimate overall survival in adults with newly diagnosed glioblastoma treated with talampanel in addition to standard radiation (RT) and temozolomide (TMZ)."5.14Talampanel with standard radiation and temozolomide in patients with newly diagnosed glioblastoma: a multicenter phase II trial. ( Batchelor, T; Chamberlain, M; Desideri, S; Fine, HA; Fisher, J; Grossman, SA; Mikkelsen, T; Piantadosi, S; Ye, X, 2009)
"The use of radiotherapy plus temozolomide administered concomitantly with and after radiotherapy for glioblastoma was recently shown to improve median and 2-year survival in a large international multicenter study."5.14Clinical outcome of concomitant chemoradiotherapy followed by adjuvant temozolomide therapy for glioblastaomas: single-center experience. ( Jeon, HJ; Kim, JH; Kim, ST; Kim, WS; Kong, DS; Lee, JI; Lim, DH; Nam, DH; Park, K; Park, KB, 2009)
"To present outcome data in a prospective study of radiotherapy (RT) with concurrent and adjuvant temozolomide (TMZ) in children with diffuse intrinsic pontine gliomas (DIPGs)."5.14Prospective evaluation of radiotherapy with concurrent and adjuvant temozolomide in children with newly diagnosed diffuse intrinsic pontine glioma. ( Arora, B; Dutta, D; Gupta, T; Jalali, R; Kurkure, P; Munshi, A; Raut, N; Sarin, R, 2010)
"This multicenter phase II study conducted by the Spanish Neuro-Oncology Group evaluated the activity of an extended, dose-dense temozolomide regimen in patients with temozolomide-refractory malignant glioma."5.14Extended-schedule dose-dense temozolomide in refractory gliomas. ( Balaña, C; Berrocal, A; Gallego, O; Garcia Lopez, J; Gil, M; Iglesias, L; Perez Segura, P; Reynes, G; Rodríguez, J; Yaya, R, 2010)
"Because of the poor outcomes for patients with recurrent glioblastoma multiforme (GBM), and some laboratory and clinical evidence of efficacy using interferon in GBM, we assessed the toxicity and efficacy of temozolomide (TMZ) combined with either short-acting (IFN) or long-acting (pegylated) interferon alpha2b (PEG) in two single-arm phase II studies, and compared the results to 6-month progression-free survival (PFS-6) data from historical controls."5.14Two phase II trials of temozolomide with interferon-alpha2b (pegylated and non-pegylated) in patients with recurrent glioblastoma multiforme. ( Alfred Yung, WK; Conrad, CA; Gilbert, MR; Groves, MD; Hess, KR; Hunter, K; Levin, VA; Liu, VH; Meyers, C; Puduvalli, VK, 2009)
"To determine the maximum tolerated dose (MTD) of fractionated intensity-modulated radiotherapy (IMRT) with temozolomide (TMZ) in patients with glioblastoma."5.14A phase I dose-escalation study (ISIDE-BT-1) of accelerated IMRT with temozolomide in patients with glioblastoma. ( Balducci, M; Calista, F; Cantore, GP; Cellini, N; Cilla, S; Deodato, F; Digesù, C; Esposito, V; Ferro, M; Ianiri, M; Macchia, G; Morganti, AG; Piermattei, A; Romanelli, P; Salvati, M; Valentini, V, 2010)
"This alternating weekly, dose-dense temozolomide regimen was well tolerated and clinically active in heavily pretreated patients with brain metastases, particularly in patients with melanoma."5.14Dose-dense temozolomide regimen for the treatment of brain metastases from melanoma, breast cancer, or lung cancer not amenable to surgery or radiosurgery: a multicenter phase II study. ( Bajetta, E; Cascinu, S; Crinò, L; Danova, M; Del Prete, S; Salvagni, S; Schiavetto, I; Siena, S; Vitali, M, 2010)
"Chemoradiotherapy followed by monthly temozolomide (TMZ) is the standard of care for patients with glioblastoma multiforme (GBM)."5.14Population-based study of pseudoprogression after chemoradiotherapy in GBM. ( Cairncross, JG; de Robles, PA; Dharmawardene, M; Easaw, JC; Forsyth, PA; Hamilton, MG; Magliocco, AM; McIntyre, JB; Parney, IF; Roldán, GB; Scott, JN; Yan, ES, 2009)
"To evaluate the toxicity and efficacy of chemoradiotherapy with temozolomide (TMZ) administered in an intensified 1-week on/1-week off schedule plus indomethacin in patients with newly diagnosed glioblastoma."5.14Chemoradiotherapy of newly diagnosed glioblastoma with intensified temozolomide. ( Bähr, O; Bamberg, M; Gorlia, T; Hartmann, C; Herrlinger, U; Meyermann, R; Tatagiba, M; von Deimling, A; Weiler, M; Weller, M; Wick, W; Wiewrodt, D, 2010)
"Heavily pre-treated patients with temozolomide-refractory high-grade malignant glioma received cisplatin at a dose of 75 mg/m(2) on day 1 and temozolomide at a dose of 150 mg/m(2) on days 1 to 5 every 21 days until progression or major toxicity."5.14A phase II study of cisplatin and temozolomide in heavily pre-treated patients with temozolomide-refractory high-grade malignant glioma. ( Della Puppa, A; Lombardi, G; Pastorelli, D; Rotilio, A; Scienza, R; Zustovich, F, 2009)
"We retrospectively investigated the correlation of IDH1 and IDH2 mutations with overall survival and response to temozolomide in a cohort of patients with dedifferentiated low-grade astrocytomas treated with temozolomide at the time of progression after radiotherapy."5.14IDH1 mutations in low-grade astrocytomas predict survival but not response to temozolomide. ( Boogerd, W; Bromberg, JE; Dinjens, WN; Dubbink, HJ; Gijtenbeek, JM; Groenendijk, FH; Kros, JM; Postma, TJ; Smitt, PA; Taal, W; van den Bent, MJ; van Heuvel, I; van Marion, R; Zonnenberg, BA; Zonnenberg, CB, 2009)
"To investigate the efficacy and safety of temozolomide (TMZ) and lomustine (CCNU) in malignant brain gliomas."5.14[A multicenter randomized controlled study of temozolomide in 97 patients with malignant brain glioma]. ( Chang, Y; Fu, Z; Liu, XM; Liu, XY; Qian, ZZ; Wang, HQ; Yang, SY; Yu, H, 2009)
"Thirteen patients with temozolomide-refractory anaplastic oligodendroglioma (11 patients) or oligoastrocytoma (2 patients) underwent blood-brain barrier disruption with carboplatin (IA, 200 mg/m(2)/d), etoposide phosphate (IV, 200 mg/m(2)/d), and melphalan (IA, dose escalation) every 4 weeks, for up to 1 year."5.14Intra-arterial chemotherapy with osmotic blood-brain barrier disruption for aggressive oligodendroglial tumors: results of a phase I study. ( Delashaw, JB; Doolittle, ND; Gahramanov, S; Guillaume, DJ; Hedrick, NA; Neuwelt, EA, 2010)
"We conducted a phase I study to determine the safety and recommended phase II dose of enzastaurin (oral inhibitor of the protein kinase C-beta [PKCbeta] and the PI3K/AKT pathways) when given in combination with radiation therapy (RT) plus temozolomide to patients with newly diagnosed glioblastoma multiforme or gliosarcoma."5.14Enzastaurin plus temozolomide with radiation therapy in glioblastoma multiforme: a phase I study. ( Butowski, N; Chang, SM; Hristova-Kazmierski, M; Lamborn, KR; Musib, L; Nicol, SJ; Parvataneni, R; Polley, MY; Prados, MD; Thornton, DE, 2010)
"We assessed six-month progression-free survival (PFS) as an alternative primary efficacy endpoint to overall survival in newly diagnosed glioblastoma multiforme (GBM) patients receiving temozolomide (TMZ)."5.14Six-month progression-free survival as an alternative primary efficacy endpoint to overall survival in newly diagnosed glioblastoma patients receiving temozolomide. ( Butowski, N; Chang, SM; Clarke, JL; Lamborn, KR; Polley, MY; Prados, M, 2010)
"To determine the maximum tolerated dose of ABT-510, a thrombospondin-1 mimetic drug with antiangiogenic properties, when used concurrently with temozolomide and radiotherapy in patients with newly diagnosed glioblastoma."5.14A phase 1 trial of ABT-510 concurrent with standard chemoradiation for patients with newly diagnosed glioblastoma. ( Fathallah-Shaykh, HM; Fiveash, JB; Gillespie, GY; Gladson, CL; Huang, Z; Johnson, MJ; Kekan, MS; Kuo, H; Markert, JM; Meleth, S; Nabors, LB, 2010)
"PURPOSE Concomitant temozolomide (TMZ)/radiotherapy followed by adjuvant TMZ has increased survival in patients with glioblastoma multiforme (GBM)."5.14Phase II trial of continuous dose-intense temozolomide in recurrent malignant glioma: RESCUE study. ( Bélanger, K; Easaw, J; Eisenstat, DD; Forsyth, P; Fulton, D; Kavan, P; Kirby, S; Macdonald, DR; Mason, WP; Perry, JR; Pouliot, JF; Shields, C; Thiessen, B, 2010)
"Twenty-two patients with newly diagnosed malignant glioma who received standard radiation/temozolomide therapy were recruited for the study."5.14Effects of concomitant temozolomide and radiation therapies on WT1-specific T-cells in malignant glioma. ( Chiba, Y; Hashimoto, N; Hosen, N; Kagawa, N; Kinoshita, M; Murao, A; Nishida, S; Oji, Y; Oka, Y; Sugiyama, H; Tsuboi, A; Yoshimine, T, 2010)
" Forty newly diagnosed patients (11 anaplastic oligodendrogliomas [OD] and 29 anaplastic oligoastrocytomas [OA]) were enrolled into this multicenter, open-label, single-arm Phase II trial of first-line temozolomide (200 mg/m(2) on days 1-5 every 4 weeks for 6 cycles)."5.14A phase II trial of primary temozolomide in patients with grade III oligodendroglial brain tumors. ( Algar, E; Benson, A; Cher, L; Dowling, A; Gan, HK; Kalnins, R; Rosenthal, MA; Wong, N; Woods, AM, 2010)
"The aim of this clinical trial was to investigate safety and efficacy when combining cetuximab with bevacizumab and irinotecan in patients with recurrent primary glioblastoma multiforme (GBM)."5.14Cetuximab, bevacizumab, and irinotecan for patients with primary glioblastoma and progression after radiation therapy and temozolomide: a phase II trial. ( Broholm, H; Hansen, S; Hasselbalch, B; Holmberg, M; Kosteljanetz, M; Lassen, U; Poulsen, HS; Stockhausen, MT; Sørensen, M, 2010)
"Compared with historical controls, the addition of concomitant and adjuvant cilengitide to standard chemoradiotherapy demonstrated promising activity in patients with glioblastoma with MGMT promoter methylation."5.14Phase I/IIa study of cilengitide and temozolomide with concomitant radiotherapy followed by cilengitide and temozolomide maintenance therapy in patients with newly diagnosed glioblastoma. ( Clement, PM; Dietrich, PY; Diserens, AC; Goldbrunner, R; Grabenbauer, GG; Hegi, ME; Hermisson, M; Hicking, C; Krueger, S; Neyns, B; Ochsenbein, AF; Pica, A; Picard, M; Pietsch, T; Schlegel, U; Simon, M; Stupp, R; Tonn, JC; Weller, M, 2010)
"The current study was conducted to evaluate the efficacy of sorafenib, an oral vascular endothelial growth factor receptor tyrosine kinase inhibitor, when added to standard radiotherapy and temozolomide in the first-line treatment of patients with glioblastoma multiforme."5.14Concurrent radiotherapy and temozolomide followed by temozolomide and sorafenib in the first-line treatment of patients with glioblastoma multiforme. ( Clark, BL; Ervin, T; Friedman, E; Hainsworth, JD; Lamar, RE; Murphy, PB; Priego, V, 2010)
"The objectives of this study were to determine the safety and efficacy of polyinosinic-polycytidylic acid stabilized with poly-l-lysine and carboxymethylcellulose (poly-ICLC) when added to radiation and temozolomide (TMZ) in adults with newly diagnosed glioblastoma (GB)."5.14A multi-institution phase II study of poly-ICLC and radiotherapy with concurrent and adjuvant temozolomide in adults with newly diagnosed glioblastoma. ( Batchelor, TT; Chamberlain, MC; Desideri, S; Grossman, SA; Lesser, GJ; Peereboom, DM; Rosenfeld, MR; Salazar, AM; Ye, X, 2010)
"Treatment standard for patients with primary glioblastoma (GBM) is combined radiochemotherapy with temozolomide (TMZ)."5.14Randomized phase II study evaluating a carbon ion boost applied after combined radiochemotherapy with temozolomide versus a proton boost after radiochemotherapy with temozolomide in patients with primary glioblastoma: the CLEOPATRA trial. ( Combs, SE; Debus, J; Haberer, T; Habermehl, D; Haselmann, R; Jäkel, O; Kieser, M; Nikoghosyan, A; Rieken, S; Unterberg, A; Wick, W, 2010)
"Temozolomide (TMZ) is an oral alkylating agent with demonstrated efficacy as second-line therapy for patients with recurrent anaplastic astrocytoma and glioblastoma multiforme (GBM)."5.14The outcomes of concomitant radiation plus temozolomide followed by adjuvant temozolomide for newly diagnosed high grade gliomas: the preliminary results of single center prospective study. ( Abo Hamar, AH; El-Shorbagy, D; Galal, S; Shawky, H; Zakaria, F, 2009)
"To evaluate efficacy and safety of fotemustine chemotherapy in temozolomide (TMZ) pretreated adults with recurrent glioblastoma multiforme (GBM)."5.13Second-line chemotherapy with fotemustine in temozolomide-pretreated patients with relapsing glioblastoma: a single institution experience. ( Ammannati, F; Biti, G; Bordi, L; Borghesi, S; Detti, B; Iannalfi, A; Leonulli, BG; Martinelli, F; Meattini, I; Sardaro, A; Scoccianti, S, 2008)
"We performed a new phase II trial enrolling patients with newly diagnosed high-grade glioma (HGG) to test the efficacy of a weekly alternating temozolomide (TMZ) schedule after surgery and concomitant chemoradiotherapy."5.13Dose-intensity temozolomide after concurrent chemoradiotherapy in operated high-grade gliomas. ( D'Amico, A; Dall'oglio, S; Gabbani, M; Maluta, S; Pasini, F; Passarin, MG; Pioli, F; Talacchi, A; Turazzi, S, 2008)
"The combination of temozolomide (TMZ) and thalidomide was reported to produce a high response rate, including shrinkage of brain metastases, in patients with metastatic melanoma."5.13Temozolomide, thalidomide, and whole brain radiation therapy for patients with brain metastasis from metastatic melanoma: a phase II Cytokine Working Group study. ( Agarwala, S; Atkins, MB; Clark, JI; Curti, B; Dutcher, JP; Ernstoff, MS; Lawson, D; Logan, T; Margolin, KA; Sosman, JA; Weiss, G, 2008)
"A multicenter phase I clinical trial, namely, Integrated Japanese Multicenter Clinical Trial: A Phase I Study of Interferon-beta and Temozolomide for Glioma in Combination with Radiotherapy (INTEGRA Study), is being conducted for patients with high-grade glioma in order to evaluate the safety, feasibility and preliminary clinical effectiveness of the combination of interferon-beta and temozolomide."5.13A multicenter phase I trial of interferon-beta and temozolomide combination therapy for high-grade gliomas (INTEGRA Study). ( Aoki, T; Hashimoto, N; Kayama, T; Kurisu, K; Natsume, A; Nishikawa, R; Ogura, M; Takahashi, H; Wakabayashi, T; Yoshida, J; Yoshimine, T, 2008)
"To evaluate the efficacy of simultaneous postoperative temozolomide radiochemotherapy in glioblastoma patients."5.13Randomized study of postoperative radiotherapy and simultaneous temozolomide without adjuvant chemotherapy for glioblastoma. ( Becker, G; Borberg, SK; Fischedick, AR; Frommolt, P; Grauthoff, H; Herfarth, K; Kocher, M; Müller, RP; Niewald, M; Rühl, U; Staar, S; Steingräber, M; Stuschke, M, 2008)
"This is a phase-I study of gefitinib in combination with temozolomide in patients with gliomas."5.13Phase-1 trial of gefitinib and temozolomide in patients with malignant glioma: a North American brain tumor consortium study. ( Chang, S; Cloughesy, T; Dancey, J; Fink, K; Junck, L; Kuhn, J; Prados, MD; Robins, HI; Wen, PY; Yung, WK, 2008)
"The study aimed to compare the cost-effectiveness of concomitant and adjuvant temozolomide (TMZ) for the treatment of newly diagnosed glioblastoma multiforme versus initial radiotherapy alone from a public health care perspective."5.13Cost-effectiveness of temozolomide for the treatment of newly diagnosed glioblastoma multiforme: a report from the EORTC 26981/22981 NCI-C CE3 Intergroup Study. ( Al, MJ; Crott, R; Gorlia, T; Jin Seung, S; Lamers, LM; Mittmann, N; Stupp, R; Uyl-de Groot, CA; van den Bent, MJ; Wasserfallen, JB, 2008)
"Twice-daily dosing may enhance the efficacy of temozolomide in the treatment of recurrent gliomas without increasing toxicity."5.13Multi-institutional phase II study of temozolomide administered twice daily in the treatment of recurrent high-grade gliomas. ( Alavi, J; Balmaceda, C; Chen, J; Cheung, YK; Fine, RL; Fisher, PG; Pannullo, S; Peereboom, D; Sisti, M, 2008)
"To evaluate toxicity and outcomes in patients with primary glioblastoma (GB) treated with postoperative radiochemotherapy (RCHT) with temozolomide (TMZ) comparing two dose regimens."5.13Radiochemotherapy in patients with primary glioblastoma comparing two temozolomide dose regimens. ( Bischof, M; Combs, SE; Debus, J; Edler, L; Rausch, R; Schulz-Ertner, D; Wagner, F; Wagner, J; Welzel, T; Zabel-du Bois, A, 2008)
"We conducted a single institution phase II trial to evaluate the tolerability and effectiveness of therapy with arsenic trioxide (ATO) and ascorbic acid (AA) with temozolomide (TMZ) in patients with advanced melanoma."5.13Phase II trial of arsenic trioxide and ascorbic acid with temozolomide in patients with metastatic melanoma with or without central nervous system metastases. ( Bael, TE; Gollob, JA; Peterson, BL, 2008)
"To assess interim safety and tolerability of a 10-patient, Phase II pilot study using bevacizumab (BV) in combination with temozolomide (TMZ) and regional radiation therapy (RT) in the up-front treatment of patients with newly diagnosed glioblastoma."5.13Phase II pilot study of bevacizumab in combination with temozolomide and regional radiation therapy for up-front treatment of patients with newly diagnosed glioblastoma multiforme: interim analysis of safety and tolerability. ( Bergsneider, M; Cloughesy, T; Filka, E; Graham, C; Lai, A; Liau, LM; McGibbon, B; Mischel, P; Nghiemphu, PL; Pope, W; Selch, M; Yong, WH, 2008)
"We determined the maximum tolerated dose (MTD) and dose-limiting toxicity (DLT) of imatinib mesylate, an inhibitor of the receptor tyrosine kinases platelet-derived growth factor receptor (PDGFR), the proto-oncogene product c-kit, and the fusion protein Bcr-Abl, when administered for 8 days in combination with temozolomide (TMZ) to malignant glioma (MG) patients."5.13Safety and pharmacokinetics of dose-intensive imatinib mesylate plus temozolomide: phase 1 trial in adults with malignant glioma. ( Desjardins, A; Egorin, MJ; Friedman, AH; Friedman, HS; Gururangan, S; Herndon, JE; Lagattuta, TF; McLendon, R; Quinn, JA; Reardon, DA; Rich, JN; Salvado, AJ; Sathornsumetee, S; Vredenburgh, JJ, 2008)
"The primary objective of this prospective phase 2 study of CPT-11 in adult patients with recurrent temozolomide-refractory anaplastic astrocytoma (AA) was to evaluate 6-month progression-free survival (PFS)."5.13Salvage chemotherapy with CPT-11 for recurrent temozolomide-refractory anaplastic astrocytoma. ( Blumenthal, DT; Chamberlain, MC; Glantz, MJ; Wei-Tsao, DD, 2008)
"We conducted a phase II study of the combination of temozolomide and angiogenesis inhibitors for treating adult patients with newly diagnosed glioblastoma."5.13Phase II study of temozolomide, thalidomide, and celecoxib for newly diagnosed glioblastoma in adults. ( Batchelor, TT; Black, PM; Ciampa, A; Doherty, L; Drappatz, J; Folkman, J; Gigas, DC; Henson, JW; Kesari, S; Kieran, M; Laforme, A; Ligon, KL; Longtine, JA; Muzikansky, A; Ramakrishna, N; Schiff, D; Weaver, S; Wen, PY, 2008)
"The aim of the present study was to determine in patients with progressive or recurrent low grade gliomas, the response rate and toxicity incurred by a continued schedule of temozolomide chemotherapy administered before radiation therapy, and to explore correlations between response and survival with 1p/19q deletions and MGMT promoter methylation status."5.13Temozolomide three weeks on and one week off as first line therapy for patients with recurrent or progressive low grade gliomas. ( Bertorelle, R; Blatt, V; Bonaldi, L; Brandes, AA; Ermani, M; Franceschi, E; Tosoni, A, 2008)
"To evaluate outcome after fractionated stereotactic radiotherapy (FSRT) and concomitant daily temozolomide (TMZ) in patients with recurrent gliomas."5.13Radiochemotherapy with temozolomide as re-irradiation using high precision fractionated stereotactic radiotherapy (FSRT) in patients with recurrent gliomas. ( Bischof, M; Combs, SE; Debus, J; Hof, H; Oertel, S; Schulz-Ertner, D; Welzel, T, 2008)
"A Phase II study of CPT-11 in adults with recurrent, temozolomide (TMZ)-refractory, 1p19q co-deleted, anaplastic oligodendroglioma (AO) with a primary objective of determining 6-month progression free survival (PFS)."5.13CPT-11 for recurrent temozolomide-refractory 1p19q co-deleted anaplastic oligodendroglioma. ( Chamberlain, MC; Glantz, MJ, 2008)
"A phase I trial was conducted to determine the maximum tolerated dose (MTD) of temozolomide given in combination with lomustine in newly diagnosed pediatric patients with high-grade gliomas."5.13A phase I trial of temozolomide and lomustine in newly diagnosed high-grade gliomas of childhood. ( Adamson, PC; Blaney, SM; Flom, L; Ingle, AM; Jakacki, RI; Pollack, IF; Prados, MD; Timmerman, R; Yates, A; Zhou, T, 2008)
"We performed a Cochrane Review to examine studies using different techniques to measure MGMT and predict survival in glioblastoma patients treated with temozolomide."5.12MGMT promoter methylation testing to predict overall survival in people with glioblastoma treated with temozolomide: a comprehensive meta-analysis based on a Cochrane Systematic Review. ( Brandner, S; Cheng, HY; Dawson, S; Faulkner, CL; Higgins, JPT; Jefferies, S; Kelly, C; Kurian, KM; McAleenan, A; Schmidt, L; Spiga, F; Wragg, C, 2021)
"Temozolomide is an oral alkylating agent incorporated in the treatment of glioblastoma multiforme (GBM) that can lead to lymphopenia."5.12Temozolomide is a risk factor for invasive pulmonary aspergillosis: A case report and literature review. ( Brault, C; Chouaki, T; Maizel, J; Nyga, R; Zerbib, Y, 2021)
"Recent developments in pharmacogenomics have created opportunities for predicting temozolomide response in gliomas."5.12Comprehensive pharmacogenomics characterization of temozolomide response in gliomas. ( Long, J; Tong, S; Wang, B; Wang, Y; Wu, J; Zhong, P, 2021)
"We searched Medline and Embase (Jan 1994-Jan 2021) for studies evaluating the effect of temozolomide monotherapy on cell viability of at least one malignant glioma cell line."5.12Temozolomide sensitivity of malignant glioma cell lines - a systematic review assessing consistencies between in vitro studies. ( Brennan, PM; Bruce, M; Hannan, CJ; Poon, MTC; Simpson, JE, 2021)
"Steroids are commonly used for managing brain edema in patients with glioblastoma multiforme (GBM), treated with surgery and concomitant temozolomide-based chemoradiotherapy (CTRT)."5.12Steroids use and survival in patients with glioblastoma multiforme: a pooled analysis. ( Bruschieri, L; De Stefani, A; Dottorini, L; Ghidini, A; Iaculli, A; Petrelli, F; Riboldi, V; Trevisan, F; Zaniboni, A, 2021)
"Temozolomide (TMZ) is an oral alkylating agent principally indicated for neurological malignancies including glioblastoma (GBM) and astrocytoma."5.12Temozolomide-induced aplastic anaemia: Case report and review of the literature. ( Gilbar, PJ; Mangos, HM; Pokharel, K, 2021)
"To determine which method for assessing MGMT methylation status best predicts overall survival in people diagnosed with glioblastoma who are treated with temozolomide."5.12Prognostic value of test(s) for O6-methylguanine-DNA methyltransferase (MGMT) promoter methylation for predicting overall survival in people with glioblastoma treated with temozolomide. ( Brandner, S; Cheng, HY; Dawson, S; Faulkner, CL; Higgins, JPT; Howell, A; Jefferies, S; Kelly, C; Kernohan, A; Kurian, KM; McAleenan, A; Robinson, T; Schmidt, L; Spiga, F; Vale, L; Wragg, C, 2021)
"The standard of care treatment for glioblastoma is surgical resection followed by radiotherapy to 60 Gy with concurrent and adjuvant temozolomide with or without tumor-treating fields."5.12Novel Radiation Approaches. ( Kotecha, R; Mehta, MP; Tom, MC, 2021)
"Limited evidence is available on the utility of dose-escalated radiation therapy (DE-RT) with or without temozolomide (TMZ) versus standard-of-care radiation therapy (SoC-RT) for patients with newly diagnosed glioblastoma multiforme."5.12Dose Escalated Radiation Therapy for Glioblastoma Multiforme: An International Systematic Review and Meta-Analysis of 22 Prospective Trials. ( Bovi, J; Brown, PD; Gondi, V; Lehrer, EJ; Navarria, P; Palmer, JD; Perlow, HK; Scoccianti, S; Singh, R; Trifiletti, DM; Wang, M; Zaorsky, NG, 2021)
"In this review, we discuss the use of the alkylating agent temozolomide (TMZ) in the treatment of IDH-mutant gliomas."5.12From Laboratory Studies to Clinical Trials: Temozolomide Use in IDH-Mutant Gliomas. ( Sun, X; Turcan, S, 2021)
"(1) Background: Studies in elderly patients over the age of 65 with glioblastoma have shown survival benefits of short-course radiation therapy with concurrent and adjuvant temozolomide, making it the standard of care adopted at Juravinski Cancer Center."5.12Outcomes in Elderly Patients with Glioblastoma Multiforme Treated with Short-Course Radiation Alone Compared to Short-Course Radiation and Concurrent and Adjuvant Temozolomide Based on Performance Status and Extent of Resection. ( Greenspoon, JN; Mir, T; Pond, G, 2021)
"The objective of the study was to evaluate the efficacy and toxicity of Temozolomide (TMZ) administered for 5 consecutive days in three daily dosing in children with recurrent or refractory high-grade glioma."5.12Phase II trial of temozolomide in children with recurrent high-grade glioma. ( Abate, ME; Attinà, G; Caldarelli, M; Cefalo, G; Clerico, A; Colosimo, C; Di Rocco, C; Garré, ML; Lazzareschi, I; Madon, E; Massimino, M; Maurizi, P; Mazzarella, G; Riccardi, R; Ridola, V; Ruggiero, A; Sandri, A, 2006)
"A prospective Phase II study of cyclophosphamide (CYC) was conducted in adult patients with recurrent temozolomide-refractory anaplastic astrocytoma (AA) with a primary objective of evaluating 6-month progression-free survival (PFS)."5.12Salvage chemotherapy with cyclophosphamide for recurrent temozolomide-refractory anaplastic astrocytoma. ( Chamberlain, MC; Groshen, S; Tsao-Wei, DD, 2006)
"Temozolomide (TMZ) a recent, oral, second generation alkylating agent is a chemotherapeutic with demonstrated efficacy for the treatment of high-grade gliomas."5.12Surgery, radiotherapy and temozolomide in treating high-grade gliomas. ( Barbarisi, M; Moraci, A; Moraci, M; Parlato, C, 2006)
"Our objective was to evaluate the toxicity and antitumor efficacy of concurrent biochemotherapy in metastatic melanoma patients and the effectiveness of adding temozolomide to protect the brain from metastases."5.12A biochemotherapy regimen with concurrent administration of cisplatin, vinblastine, temozolomide (Temodal), interferon-alfa and interleukin-2 for metastatic melanoma: a phase II study. ( Asna, N; Inbar, MJ; Metser, U; Ron, IG; Ryvo, L; Safra, T; Sapir, EE; Sarid, D; Schneebaum, S, 2006)
"The purpose of this study was to define the maximum tolerated dose of erlotinib and characterize its pharmaco-kinetics and safety profile, alone and with temozolomide, with and without enzyme-inducing antiepileptic drugs (EIAEDs), in patients with malignant gliomas."5.12Phase 1 study of erlotinib HCl alone and combined with temozolomide in patients with stable or recurrent malignant glioma. ( Burton, E; Butowski, N; Chang, S; Fedoroff, A; Kapadia, A; Kelley, SK; Lamborn, KR; Malec, M; Page, MS; Prados, MD; Rabbitt, J; Xie, D, 2006)
"Since anaplastic gliomas (AG) depend on matrix metalloproteinases for tumor cell invasion and angiogenesis, we undertook this phase II study to evaluate the matrix metalloproteinase inhibitor marimastat (MT), combined with the alkylator temozolomide (TMZ) in patients with recurrent AG, looking for improved outcomes."5.12Phase II trial of temozolomide plus marimastat for recurrent anaplastic gliomas: a relationship among efficacy, joint toxicity and anticonvulsant status. ( Aldape, KD; Conrad, CA; Gilbert, MR; Groves, MD; Hess, KR; Jaeckle, K; Levin, VA; Liu, V; Puduvalli, VK; Yung, WK, 2006)
"The implementation of combined radiochemotherapy (RCHT) with temozolomide (TMZ) has lead to a significant increase in overall survival times in patients with Glioblastoma multiforme (GBM), however, outcome still remains unsatisfactory."5.12Treatment of primary glioblastoma multiforme with cetuximab, radiotherapy and temozolomide (GERT)--phase I/II trial: study protocol. ( Combs, SE; Debus, J; Edler, L; Haselmann, R; Heeger, S; Schulz-Ertner, D, 2006)
"The European Organisation for Research and Treatment of Cancer and National Cancer Institute of Canada trial on temozolomide (TMZ) and radiotherapy (RT) in glioblastoma (GBM) has demonstrated that the combination of TMZ and RT conferred a significant and meaningful survival advantage compared with RT alone."5.12Radiotherapy and temozolomide for newly diagnosed glioblastoma: recursive partitioning analysis of the EORTC 26981/22981-NCIC CE3 phase III randomized trial. ( Allgeier, A; Brandes, AA; Cairncross, G; Curschmann, J; Fisher, B; Gorlia, T; Kortmann, RD; Lacombe, D; Mason, W; Mirimanoff, RO; Reni, M; Stupp, R; Van den Bent, MJ; Villa, S, 2006)
"A single-institution Phase I clinical trial was conducted to determine the maximum tolerated dose (MTD) and define the safety profile of temozolomide and capecitabine when used in combination to treat brain metastases from breast cancer."5.12Phase I study of capecitabine in combination with temozolomide in the treatment of patients with brain metastases from breast carcinoma. ( Arun, B; Broglio, K; Buchholz, T; Francis, D; Groves, M; Hortobagyi, GN; Meyers, C; Rivera, E; Valero, V; Yin, G, 2006)
"Concurrent temozolomide (TMZ) and radiotherapy is the new standard of care for patients with newly diagnosed glioblastoma."5.12Early necrosis following concurrent Temodar and radiotherapy in patients with glioblastoma. ( Chalmers, L; Chamberlain, MC; Glantz, MJ; Sloan, AE; Van Horn, A, 2007)
"To date, no data are available on the relationship between 1p/19q deletions and the response to temozolomide (TMZ) in primary anaplastic oligodendroglioma (AO) and anaplastic oligoastrocytoma (AOA) recurrent after surgery and standard radiotherapy."5.12Correlations between O6-methylguanine DNA methyltransferase promoter methylation status, 1p and 19q deletions, and response to temozolomide in anaplastic and recurrent oligodendroglioma: a prospective GICNO study. ( Bertorelle, R; Blatt, V; Bonaldi, L; Brandes, AA; Cavallo, G; Ermani, M; Franceschi, E; Gardiman, M; Ghimenton, C; Iuzzolino, P; Pession, A; Reni, M; Tosoni, A, 2006)
"The efficacy and safety of temozolomide were evaluated in 32 patients with anaplastic astrocytoma at first relapse."5.12[Efficacy and safety of monotherapy with temozolomide in patients with anaplastic astrocytoma at first relapse--a phase II clinical study]. ( Aoki, T; Fujimaki, T; Hori, T; Ikeda, J; Kochi, M; Maruno, M; Matsutani, M; Nakamura, H; Nishikawa, R; Sato, S; Sawamura, Y; Shibui, S; Sugiyama, K; Takahashi, H; Takahashi, J; Wakabayashi, T, 2006)
"The combination of TMZ and celecoxib is safe and potentially effective in the treatment of metastatic melanoma."5.12Temozolomide in combination with celecoxib in patients with advanced melanoma. A phase II study of the Hellenic Cooperative Oncology Group. ( Fountzilas, G; Frangia, K; Gogas, H; Mantzourani, M; Markopoulos, C; Middleton, M; Panagiotou, P; Papadopoulos, O; Pectasides, D; Polyzos, A; Stavrinidis, I; Tsoutsos, D; Vaiopoulos, G, 2006)
"To evaluate toxicity and efficacy of the combination of lomustine, temozolomide (TMZ) and involved-field radiotherapy in patients with newly diagnosed glioblastoma (GBM)."5.12Phase II trial of lomustine plus temozolomide chemotherapy in addition to radiotherapy in newly diagnosed glioblastoma: UKT-03. ( Bamberg, M; Blaschke, B; Herrlinger, U; Hundsberger, T; Koch, D; Kortmann, RD; Loeser, S; Meyermann, R; Reifenberger, G; Rieger, J; Sommer, C; Steinbach, JP; Tan, TC; Weller, M; Wick, W, 2006)
"Preliminary studies suggesting that extended-dose temozolomide with thalidomide is safe and active in patients with metastatic melanoma have led to frequent use of this oral regimen."5.12Phase II study of temozolomide and thalidomide in patients with metastatic melanoma in the brain: high rate of thromboembolic events (CALGB 500102). ( Haluska, FG; Hodgson, L; Houghton, AN; Hwu, WJ; Krown, SE; Niedzwiecki, D, 2006)
"Temozolomide has shown some efficacy in metastatic melanoma and recently received extended approval to treat brain tumours."5.12Dose-intensified bi-weekly temozolomide in patients with asymptomatic brain metastases from malignant melanoma: a phase II DeCOG/ADO study. ( Egberts, F; Garbe, C; Hauschild, A; Kreissig, M; Linse, R; Mohr, P; Schadendorf, D; Thoelke, A; Tilgen, W; Trefzer, U; Ugurel, S; Vogt, T, 2006)
" The aim of this pilot study was to evaluate the efficacy and safety of metronomic temozolomide (TMZ) treatment in twelve consecutive patients with recurrent TMZ-refractory glioblastoma."5.12A pilot study of metronomic temozolomide treatment in patients with recurrent temozolomide-refractory glioblastoma. ( Eoh, W; Kim, JH; Kim, ST; Kim, WS; Kong, DS; Lee, JI; Lim, DH; Nam, DH; Park, K; Son, MJ, 2006)
"Laboratory and clinical data suggest that the anti-angiogenic agent, thalidomide, if combined with cytotoxic agents, may be effective against recurrent glioblastoma multiforme (GBM)."5.12A North American brain tumor consortium (NABTC 99-04) phase II trial of temozolomide plus thalidomide for recurrent glioblastoma multiforme. ( Abrey, LE; Chang, SM; Cloughesy, TF; Conrad, CA; DeAngelis, LM; Gilbert, MR; Greenberg, H; Groves, MD; Hess, KR; Lamborn, KR; Liu, TJ; Peterson, P; Prados, MD; Puduvalli, VK; Schiff, D; Tremont-Lukats, IW; Wen, PY; Yung, WK, 2007)
"Temozolomide is an alkylating agent with activity in the treatment of melanoma metastatic to the brain."5.12A phase I/II study of lomustine and temozolomide in patients with cerebral metastases from malignant melanoma. ( Bate, SC; Beirne, DA; Eisen, TG; Gibbens, IM; Gore, ME; Hughes, SA; Larkin, JM; Patel, PM; Thomas, K, 2007)
"Temozolomide (TMZ) has demonstrated activity and acceptable toxicity for the treatment of recurrent malignant gliomas in carious prospective phase II studies."5.12[Temozolomide in the treatment of recurrent malignant glioma]. ( Ishii, N; Iwasaki, Y; Kobayashi, H; Murata, J; Sawamura, Y, 2006)
"The methylation status of the O6-methylguanine-methyltransferase promoter (MGMTP) was evaluated in 68 low-grade gliomas treated by neoadjuvant temozolomide."5.12MGMT methylation: a marker of response to temozolomide in low-grade gliomas. ( Benouaich-Amiel, A; Crinière, E; Delattre, JY; Everhard, S; Hoang-Xuan, K; Kaloshi, G; Kujas, M; Lejeune, J; Marie, Y; Mokhtari, K; Sanson, M; Thillet, J, 2006)
"We conducted a phase II study to assess the efficacy of oral temozolomide (TMZ) in children with progressive low-grade glioma."5.12Temozolomide in children with progressive low-grade glioma. ( Allen, JC; Desjardins, A; Fisher, MJ; Friedman, AH; Friedman, HS; Gururangan, S; Herndon, JE; Krauser, JM; Phillips, PC; Quinn, JA; Reardon, DA; Vredenburgh, JJ; Watral, MA, 2007)
"To evaluate if timing of chemotherapy with Temozolomide (TMZ) was able to modify the outcome of glioblastoma (GBM), we analyzed two comparable series of supratentorial GBM patients, treated with surgery and radiotherapy, in which the administration of TMZ has been performed in the first group at first relapse and in the second group in newly diagnosed cases."5.12Temozolomide in glioblastoma: results of administration at first relapse and in newly diagnosed cases. Is still proposable an alternative schedule to concomitant protocol? ( Borsa, S; Campanella, R; Caroli, M; Gaini, SM; Locatelli, M; Martinelli-Boneschi, F; Mora, A; Motta, F; Prada, F; Saladino, A, 2007)
"This phase II study evaluated the efficacy and safety of a 7-day on/7-day off regimen of temozolomide before radiotherapy (RT) in patients with inoperable newly diagnosed glioblastoma."5.12Correlation between O6-methylguanine-DNA methyltransferase and survival in inoperable newly diagnosed glioblastoma patients treated with neoadjuvant temozolomide. ( Barrié, M; Braguer, D; Chinot, OL; Dufour, H; Eudes, N; Figarella-Branger, D; Fuentes, S; Lancelot, S; Martin, PM; Metellus, P; Muracciole, X; Ouafik, L, 2007)
"Evaluation of toxicity and efficacy of an alternating weekly regimen of temozolomide administered 1 week on and 1 week off in patients with recurrent glioma."5.12Efficacy and tolerability of temozolomide in an alternating weekly regimen in patients with recurrent glioma. ( Blaschke, B; Felsberg, J; Herrlinger, U; Meyermann, R; Platten, M; Reifenberger, G; Steinbach, JP; Weller, M; Wick, A; Wick, W, 2007)
"Although overall objective responses were limited, further exploration of temozolomide may be warranted in children with medulloblastoma and other PNETs, or in patients with low-grade astrocytoma, perhaps in a setting of less pretreatment than the patients in the current study, or in the context of multiagent therapy."5.12Phase 2 study of temozolomide in children and adolescents with recurrent central nervous system tumors: a report from the Children's Oncology Group. ( Bernstein, M; Fort, D; Friedman, H; Harris, MB; Kadota, R; Krailo, M; Kretschmar, CS; Mazewski, C; Nicholson, HS; Reaman, GH; Sato, J; Tedeschi-Blok, N, 2007)
"To determine the maximum tolerated dose of irinotecan when administrated with temozolomide every 28 days, in patients with recurrent malignant glioma who were also receiving CYP450 enzyme-inducing antiepileptic drugs (EIAED), and to characterize the pharmacokinetics of irinotecan and its metabolites."5.12Phase I study of temozolomide and irinotecan for recurrent malignant gliomas in patients receiving enzyme-inducing antiepileptic drugs: a north american brain tumor consortium study. ( Aldape, KD; Chang, SM; Cloughesy, T; DeAngelis, LM; Fine, H; Fink, KL; Junck, L; Kuhn, J; Lamborn, K; Lieberman, F; Loghin, ME; Metha, M; Prados, MD; Robins, IH; Wen, P; Yung, WK, 2007)
"A phase II trial was initiated to analyze the activity of continuously administered pioglitazone and rofecoxib combined with low-dose chemotherapy (capecitabine or temozolomide) in patients with high-grade gliomas (glioblastoma or anaplastic glioma)."5.12Low-dose chemotherapy in combination with COX-2 inhibitors and PPAR-gamma agonists in recurrent high-grade gliomas - a phase II study. ( Baumgart, U; Bogdahn, U; Hau, P; Hirschmann, B; Kunz-Schughart, L; Muhleisen, H; Reichle, A; Ruemmele, P; Steinbrecher, A; Weimann, E, 2007)
"Patients with recurrent malignant glioma at any time during recurrence were treated with oral temozolomide at a dose of 150 mg/m2 per day on a 5-day schedule every 28 days."5.11Temozolomide in the treatment of recurrent malignant glioma. ( Chang, SM; Lamborn, K; Malec, M; Page, M; Prados, MD; Rabbitt, J; Theodosopoulos, P, 2004)
"The purpose of this study was to evaluate the activity, measured in terms of progression-free survival (PFS) and response rates, of 1,3-bis(chloro-ethyl)-1-nitrosourea (BCNU) plus temozolomide in adult patients with recurrent glioblastoma multiforme."5.11Phase 2 study of BCNU and temozolomide for recurrent glioblastoma multiforme: North American Brain Tumor Consortium study. ( Chang, SM; Fine, HA; Fink, KL; Greenberg, HS; Hess, KR; Jaeckle, KA; Junck, L; Kuhn, J; Mehta, MP; Nicholas, MK; Prados, MD; Robins, HI; Schold, SC; Yung, WK, 2004)
"Temozolomide has established activity in the treatment of recurrent glioblastoma multiforme (GBM)."5.11Phase 2 study of temozolomide and Caelyx in patients with recurrent glioblastoma multiforme. ( Ashley, DM; Cher, LM; Chua, SL; Dowling, A; Rosenthal, MA; Wong, SS; Woods, AM, 2004)
"We report a phase II trial of cisplatinum and temozolomide (TMZ) combination in recurrent malignant glioma patients."5.11Phase II trial of cisplatin plus temozolomide, in recurrent and progressive malignant glioma patients. ( Boiardi, A; Broggi, G; Eoli, M; Lamperti, E; Maccagnano, E; Salmaggi, A; Silvani, A, 2004)
"The primary objective of the current prospective Phase II study of cyclophosphamide (CYC) in adult patients with recurrent, temozolomide-refractory glioblastoma multiforme was to evaluate 6-month progression-free survival (PFS)."5.11Salvage chemotherapy with cyclophosphamide for recurrent, temozolomide-refractory glioblastoma multiforme. ( Chamberlain, MC; Tsao-Wei, DD, 2004)
"In the setting of a prospective clinical trial, we determined the predictive value of the methylation status of the O-6-methylguanine-DNA methyltransferase (MGMT) promoter for outcome in glioblastoma patients treated with the alkylating agent temozolomide."5.11Clinical trial substantiates the predictive value of O-6-methylguanine-DNA methyltransferase promoter methylation in glioblastoma patients treated with temozolomide. ( de Tribolet, N; Dietrich, PY; Diserens, AC; Godard, S; Hegi, ME; Ostermann, S; Otten, P; Regli, L; Stupp, R; Van Melle, G, 2004)
"Temozolomide (TMZ) and 1, 3-bis (2-chloroethyl)-1-nitrosourea (BCNU) are reported to be active agents in anaplastic glioma (AG)."5.11Phase II study of neoadjuvant 1, 3-bis (2-chloroethyl)-1-nitrosourea and temozolomide for newly diagnosed anaplastic glioma: a North American Brain Tumor Consortium Trial. ( Chang, SM; Fine, H; Fink, KL; Greenberg, H; Hess, K; Jaeckle, KA; Junck, L; Kuhn, J; Mehta, M; Prados, MD; Robins, HI; Schold, C; Yung, WK, 2004)
"Cisplatin and temozolomide (TMZ) are active in glioblastoma multiforme (GBM), with different profiles of toxicity."5.11First-line chemotherapy with cisplatin plus fractionated temozolomide in recurrent glioblastoma multiforme: a phase II study of the Gruppo Italiano Cooperativo di Neuro-Oncologia. ( Basso, U; Brandes, AA; Cavallo, G; Ermani, M; Ferreri, AJ; Monfardini, S; Panucci, MG; Reni, M; Scopece, L; Tosoni, A; Vastola, F, 2004)
"To determine the safety and toxicity of carmustine (BCNU) and temozolomide (TMZ) with radiotherapy (RT) in newly diagnosed anaplastic astrocytoma."5.11Phase I study pilot arms of radiotherapy and carmustine with temozolomide for anaplastic astrocytoma (Radiation Therapy Oncology Group 9813): implications for studies testing initial treatment of brain tumors. ( Atkins, J; Bahary, JP; Barger, G; Buckner, J; Bushunow, P; Cairncross, G; Chang, SM; Choucair, A; Curran, W; Dolinskas, C; Gilbert, M; Kresl, J; Louis, DN; Mehta, M; Seiferheld, W; Share, R; Thoron, L, 2004)
"This report describes a single-centre study with temozolomide (TMZ) (200 mg m(-2) day(-1) x 5 per cycle of 28 days) in children with (recurrent) high-grade glioma."5.11Temozolomide in paediatric high-grade glioma: a key for combination therapy? ( Couanet, D; Grill, J; Kalifa, C; Lelouch-Tubiana, A; Vassal, G; Verschuur, AC, 2004)
"The authors investigated the results of PCV chemotherapy within a cohort of 24 patients treated within the EORTC study 26971 on temozolomide chemotherapy in recurrent oligodendroglioma."5.11Salvage PCV chemotherapy for temozolomide-resistant oligodendrogliomas. ( Allgeier, A; Brandes, AA; Enting, RH; Frenay, M; Kros, JM; Menten, J; Stege, EB; Taphoorn, MJ; Tosoni, A; Triebels, VH; van den Bent, MJ; van Heuvel, I, 2004)
"Thirty-two patients with relapsing glioma were treated with temozolomide in two university hospitals in Finland."5.11Temozolomide treatment in glioma--experiences in two university hospitals in Finland. ( Aaltonen, K; Mäenpää, HO; Mäntylä, R; Minn, H, 2004)
"An analysis of 73 patients with hystologically confirmed glioblastoma multiforme (GBM), treated with the ''3 step'' (90)Y-biotin based LR-RIT, is herein reported."5.11Combined treatment of glioblastoma patients with locoregional pre-targeted 90Y-biotin radioimmunotherapy and temozolomide. ( Bartolomei, M; Bodei, L; Grana, C; Handkiewicz-Junak, D; Maira, G; Mazzetta, C; Paganelli, G; Rocca, P; Sturiale, C; Villa, G, 2004)
"Seventy-five consecutive patients with recurrent malignant astrocytomas and glioblastomas had been treated at our institute with per os temozolomide for five days every month."5.11Temozolomide chemotherapy of patients with recurrent anaplastic astrocytomas and glioblastomas. ( Afra, D; Sipos, L; Vitanovics, D, 2004)
"This phase II study evaluates the activity of temozolomide and cisplatin administered before radiation therapy in newly diagnosed glioblastoma multiforme patients, in terms of response, time to progression and survival."5.11Phase II study of temozolomide and cisplatin as primary treatment prior to radiotherapy in newly diagnosed glioblastoma multiforme patients with measurable disease. A study of the Spanish Medical Neuro-Oncology Group (GENOM). ( Balaña, C; Balart, J; Ballester, R; Benavides, M; Berrocal, A; Capellades, J; Cerdá-Nicolás, M; García, JL; Herrero, A; López-Pousa, A; Martín-Broto, J; Yaya-Tur, R, 2004)
"Patients with newly diagnosed, histologically confirmed glioblastoma were randomly assigned to receive radiotherapy alone (fractionated focal irradiation in daily fractions of 2 Gy given 5 days per week for 6 weeks, for a total of 60 Gy) or radiotherapy plus continuous daily temozolomide (75 mg per square meter of body-surface area per day, 7 days per week from the first to the last day of radiotherapy), followed by six cycles of adjuvant temozolomide (150 to 200 mg per square meter for 5 days during each 28-day cycle)."5.11Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma. ( Allgeier, A; Belanger, K; Bogdahn, U; Brandes, AA; Cairncross, JG; Curschmann, J; Eisenhauer, E; Fisher, B; Gorlia, T; Janzer, RC; Lacombe, D; Ludwin, SK; Marosi, C; Mason, WP; Mirimanoff, RO; Stupp, R; Taphoorn, MJ; van den Bent, MJ; Weller, M, 2005)
"Temozolomide plus thalidomide was an active oral regimen for patients with brain metastases from malignant melanoma."5.11Temozolomide plus thalidomide in patients with brain metastases from melanoma: a phase II study. ( Chapman, PB; Houghton, AN; Hwu, WJ; Krown, SE; Lamb, LA; Lis, E; Livingston, PO; Menell, JH; Merrell, J; Panageas, KS; Williams, LJ; Wolchok, JD, 2005)
"The authors determined the maximum tolerated dose (MTD) and dose-limiting toxicity (DLT) of irinotecan (CPT-11), a topoisomerase I inhibitor, when administered with temozolomide among patients with recurrent malignant glioma (MG)."5.11Phase I trial of irinotecan plus temozolomide in adults with recurrent malignant glioma. ( Badruddoja, M; Burkart, JL; Desjardins, A; Dowell, JM; Friedman, AH; Friedman, HS; Gururangan, S; Herndon, JE; McLendon, R; Newton, HB; Provenzale, J; Quinn, JA; Reardon, DA; Rich, JN; Sathornsumetee, S; Vredenburgh, J, 2005)
" Food and Drug Administration approved temozolomide (Temodar capsules, Schering-Plough Research Institute) for the treatment of adult patients with newly diagnosed glioblastoma multiforme concomitantly with radiotherapy and then as maintenance treatment."5.11Food and Drug Administration Drug approval summary: temozolomide plus radiation therapy for the treatment of newly diagnosed glioblastoma multiforme. ( Cohen, MH; Johnson, JR; Pazdur, R, 2005)
"To determine the anti-tumour efficacy and safety profile of temozolomide in local Chinese patients with recurrent malignant glioma."5.11Temozolomide in the treatment of recurrent malignant glioma in Chinese patients. ( Chan, DT; Chan, YL; Ng, HK; Poon, WS, 2005)
"In an effort to reduce the frequency of central nervous system (CNS) progression in patients with metastatic melanoma with ongoing systemic response to biochemotherapy, we modified our standard concurrent biochemotherapy regimen by replacing dacarbazine (DTIC) with oral temozolomide."5.10A phase II pilot trial of concurrent biochemotherapy with cisplatin, vinblastine, temozolomide, interleukin 2, and IFN-alpha 2B in patients with metastatic melanoma. ( Atkins, MB; Gollob, JA; McDermott, DF; Mier, JW; Parker, RA; Sorokin, P; Sosman, JA; Tutin, L, 2002)
"To determine the response rate of the malignant gliomas of childhood to an oral, daily schedule of temozolomide."5.10Temozolomide in malignant gliomas of childhood: a United Kingdom Children's Cancer Study Group and French Society for Pediatric Oncology Intergroup Study. ( Couanet, D; Doz, F; Dugan, M; Frappaz, D; Griffiths, PD; Hobson, R; Ironside, J; Jaspan, T; Jouvet, A; Lashford, LS; Pearson, AD; Robson, K; Thiesse, P; Vassal, G, 2002)
"Although temozolomide is active against recurrent malignant glioma, responses in many patients are modest and short-lived."5.10Phase I study of temozolomide and escalating doses of oral etoposide for adults with recurrent malignant glioma. ( Benita-Weiss, M; Bushunow, P; Coyle, TE; Evans, B; Friedman, H; Korones, DN; Mechtler, L; Quinn, JA; Reardon, DA, 2003)
"Temozolomide (TMZ) is an oral alkylating agent with a good safety profile and proven efficacy in the treatment of malignant glioma."5.10Phase I study of temozolamide (TMZ) combined with procarbazine (PCB) in patients with gliomas. ( Foster, T; Newlands, ES; Zaknoen, S, 2003)
"To further investigate the efficacy and safety of temozolomide plus thalidomide in patients with metastatic melanoma without brain metastases."5.10Phase II study of temozolomide plus thalidomide for the treatment of metastatic melanoma. ( Chapman, PB; Foster, T; Houghton, AN; Hwu, WJ; Krown, SE; Lamb, LA; Livingston, PO; Menell, JH; Merrell, J; Panageas, KS; Quinn, CJ; Williams, LJ; Wolchok, JD, 2003)
"The aim of this study was to assess the efficacy of temozolomide in patients with World Health Organisation (WHO) grade II gliomas treated with surgery alone using imaging and clinical criteria."5.10Phase II study of primary temozolomide chemotherapy in patients with WHO grade II gliomas. ( Abson, C; Ashley, S; Brada, M; Britton, J; Gonsalves, A; Hines, F; Sardell, S; Traish, D; Viviers, L; Westbury, C; Wilkins, P, 2003)
"Forty-three patients affected with LGG (29 astrocytoma, four oligodendroglioma and 10 mixed oligo-astrocytoma) were treated with temozolomide (TMZ) at the time of documented clinical and radiological progression."5.10Temozolomide chemotherapy for progressive low-grade glioma: clinical benefits and radiological response. ( Canalini, P; Carapella, CM; Carosi, M; Cianciulli, AM; Galiè, E; Giannarelli, D; Jandolo, B; Pace, A; Telera, S; Vidiri, A, 2003)
"Temozolomide is an effective agent in the treatment of recurrent malignant gliomas."5.10A phase II study of extended low-dose temozolomide in recurrent malignant gliomas. ( Abrey, LE; Bazylewicz, KA; Khan, RB; Malkin, MG; Raizer, JJ, 2002)
"Temozolomide is a novel oral alkylating agent that is effective against melanoma."5.10Temozolomide in combination with docetaxel in patients with advanced melanoma: a phase II study of the Hellenic Cooperative Oncology Group. ( Bafaloukos, D; Briassoulis, E; Fountzilas, G; Georgoulias, V; Gogas, H; Kalofonos, Ch; Karabelis, A; Kosmidis, P; Samantas, E; Skarlos, D, 2002)
"Temozolomide is a novel oral alkylating agent with demonstrated efficacy as second-line therapy for patients with recurrent anaplastic astrocytoma and glioblastoma multiforme (GBM)."5.10Promising survival for patients with newly diagnosed glioblastoma multiforme treated with concomitant radiation plus temozolomide followed by adjuvant temozolomide. ( de Tribolet, N; Dietrich, PY; Janzer, R; Leyvraz, S; Maeder, P; Maillard, I; Meuli, R; Miralbell, R; Mirimanoff, RO; Ostermann Kraljevic, S; Pica, A; Pizzolato, G; Porchet, F; Regli, L; Stupp, R, 2002)
"Temozolomide has shown efficacy in the treatment of metastatic melanoma similar to that of dacarbazine (DTIC), the standard chemotherapy, but with the added benefit of penetration into the central nervous system (CNS)."5.10Effect of temozolomide on central nervous system relapse in patients with advanced melanoma. ( Brampton, MH; Calvert, AH; Middleton, MR; Paul, MJ; Rustin, G; Summers, Y; Thatcher, N, 2002)
"To evaluate the antitumor effects and toxicities of whole brain irradiation (WBI) with temozolomide (TMZ) administered by prolonged oral dosing in patients with melanoma metastatic to the brain."5.10Temozolomide and whole brain irradiation in melanoma metastatic to the brain: a phase II trial of the Cytokine Working Group. ( Atkins, B; Clark, I; Dutcher, P; Ernstoff, S; Flaherty, L; Gollob, J; II Smith, W; Johnson, D; Longmate, J; Margolin, K; Sosman, J; Thompson, A; Weber, J; Weiss, G, 2002)
"To determine the antitumor efficacy and safety profile of temozolomide in patients with malignant astrocytoma at first relapse."5.09Multicenter phase II trial of temozolomide in patients with anaplastic astrocytoma or anaplastic oligoastrocytoma at first relapse. Temodal Brain Tumor Group. ( Albright, R; Brada, M; Bruner, J; Chang, SM; Dugan, M; Friedman, AH; Friedman, HS; Levin, VA; O'Neill, AM; Olson, J; Prados, MD; Rosenfeld, SS; Yaya-Tur, R; Yue, N; Yung, WK; Zaknoen, S, 1999)
"To determine whether chemotherapy with temozolomide (TMZ) versus procarbazine (PCB) for recurrent glioblastoma multiforme (GBM) was associated with improvement in health-related quality of life (HRQOL)."5.09Health-related quality of life in patients treated with temozolomide versus procarbazine for recurrent glioblastoma multiforme. ( Brada, M; Osoba, D; Prados, M; Yung, WK, 2000)
"A randomized, multicentre, open-label, phase II study compared temozolomide (TMZ), an oral second-generation alkylating agent, and procarbazine (PCB) in 225 patients with glioblastoma multiforme at first relapse."5.09A phase II study of temozolomide vs. procarbazine in patients with glioblastoma multiforme at first relapse. ( Albright, RE; Brada, M; Bruner, J; Fink, K; Fredericks, R; Friedman, H; Glantz, M; Greenberg, H; Hohl, RJ; Levin, VA; Olson, J; Osoba, D; Phillips, P; Prados, MD; Rampling, R; Selker, RG; Shapiro, W; Spence, A; Vick, NA; Yue, N; Yung, WK; Zaknoen, S, 2000)
"One of the objectives of this phase II study was to determine whether temozolomide (TMZ) improved the health-related quality of life (HRQL) of patients with recurrent anaplastic astrocytoma (AA)."5.09Health-related quality of life in patients with anaplastic astrocytoma during treatment with temozolomide. ( Brada, M; Osoba, D; Prados, MD; Yung, WK, 2000)
"Forty-one patients with high-grade glioma, at second recurrence or progression, of which twenty-two (54%) had glioblastoma multiforme, ten (24%) anaplastic astrocytoma, and nine (22%) anaplastic oligodendroglioma were administered temozolomide, 150 mg/m2/daily for five days every four weeks."5.09Temozolomide as a second-line systemic regimen in recurrent high-grade glioma: a phase II study. ( Amistà, P; Basso, U; Berti, F; Brandes, AA; Ermani, M; Gardiman, M; Monfardini, S; Pinna, G; Rotilio, A; Scienza, R, 2001)
"We report an open-label, uncontrolled, multicenter phase II trial of temozolomide in 138 patients (intent-to-treat [ITT] population) with glioblastoma multiforme at first relapse and a Karnofsky performance status (KPS) > or = 70."5.09Multicenter phase II trial of temozolomide in patients with glioblastoma multiforme at first relapse. ( Brada, M; Bravo-Marques, JM; Bruner, J; Dietrich, PY; Dirix, LY; Dugan, M; Heimans, JJ; Henriksson, R; Hoang-Xuan, K; Macdonald, D; Rampling, R; Rao, S; Stupp, R; Yue, N; Zaknoen, S; Zonnenberg, BA, 2001)
" A novel second-generation alkylating agent, temozolomide, has recently demonstrated efficacy and safety in patients with recurrent glioblastoma multiforme and anaplastic astrocytoma."5.09Safety and efficacy of temozolomide in patients with recurrent anaplastic oligodendrogliomas after standard radiotherapy and chemotherapy. ( Barrie, M; Braguer, D; Chinot, OL; Dufour, H; Figarella-Branger, D; Grisoli, F; Honore, S; Martin, PM; Muracciole, X, 2001)
"Temozolomide, a new oral cytotoxic agent, was given to 75 patients with malignant gliomas."5.08The Charing Cross Hospital experience with temozolomide in patients with gliomas. ( Bower, M; Brampton, MH; Brock, C; Colquhoun, I; Evans, H; Glaser, MG; Illingworth, RD; Lewis, P; Newlands, ES; O'Reilly, SM; Rice-Edwards, JM; Richards, PG, 1996)
"Patients with progressive or recurrent supratentorial high-grade gliomas were entered into a multicentre phase II trial to evaluate the efficacy and toxicity of temozolomide."5.08Multicentre CRC phase II trial of temozolomide in recurrent or progressive high-grade glioma. ( Begent, RJ; Bleehen, NM; Bower, M; Brada, M; Brampton, MH; Calvert, H; Colquhoun, I; Lewis, P; Newlands, ES, 1997)
"Temozolomide, a methylating imidazotetrazinone, has antitumor activity against gliomas, malignant melanoma, and mycosis fungoides and is presently administered as a 5-day oral schedule every 4 weeks."5.08Phase I trial of temozolomide using an extended continuous oral schedule. ( Bower, M; Brampton, MH; Brock, CS; Colquhoun, I; Evans, H; Glaser, M; Newlands, ES; Roddie, M; Rustin, GJ; Wedge, SR, 1998)
"The majority of patients with high-risk lower grade gliomas (LGG) are treated with single-agent temozolomide (TMZ) and radiotherapy despite three randomized trials showing a striking overall survival benefit with adjuvant procarbazine, lomustine, and vincristine (PCV) chemotherapy and radiotherapy."5.05Radiation and chemotherapy for high-risk lower grade gliomas: Choosing between temozolomide and PCV. ( Atkins, KM; Dietrich, J; Loeffler, JS; McDuff, SGR; Oh, KS; Shih, HA, 2020)
"The efficacy of radiotherapy with adjuvant temozolomide for glioblastoma remains controversial."5.05The efficacy and safety of radiotherapy with adjuvant temozolomide for glioblastoma: A meta-analysis of randomized controlled studies. ( Feng, Y; Wang, Y, 2020)
"The association of radiotherapy and procarbazine, lomustine (CCNU), vincristine chemotherapy in low-grade oligodendrogliomas is definitely superior over radiotherapy alone, and yields median progression-free survival and overall survival values exceeding by far 10 years."5.05Is chemotherapy alone an option as initial treatment for low-grade oligodendrogliomas? ( Rudà, R; Soffietti, R; Touat, M, 2020)
"Glioblastoma (GB) is one of the most common malignancies with limited standard therapies such as surgery, radiotherapy (RT) plus temozolomide (TMZ)."5.01Prognosis of patients with newly diagnosed glioblastoma treated with molecularly targeted drugs combined with radiotherapy vs temozolomide monotherapy: A meta-analysis. ( Aru, N; Ding, YM; Jin, WY; Liu, Z; Qin, HH; Shen, X; Wang, WL; Wu, SJ, 2019)
"Temozolomide is a first-line treatment for newly diagnosed glioblastoma."5.01Evidence-Based Practice: Temozolomide Beyond Glioblastoma. ( Chua, J; Leung, D; Nafziger, E, 2019)
"Here we review tumoricidal efficacy of Vitamin D analogues in glioblastoma multiforme (GBM) and potential synergisms with retinoic acid and temozolomide based on epidemiological and cellular studies."5.01From epidemiology and neurometabolism to treatment: Vitamin D in pathogenesis of glioblastoma Multiforme (GBM) and a proposal for Vitamin D + all-trans retinoic acid + Temozolomide combination in treatment of GBM. ( Altinoz, MA; Elmaci, I; Ozpinar, A; Perez, JL, 2019)
"Although reoperation likely confers survival benefit for glioblastoma, whether the extent of resection (EOR) of the reoperation affects survival outcome has yet to be thoroughly evaluated in the current temozolomide (TMZ) era."5.01Survival Benefit of Maximal Resection for Glioblastoma Reoperation in the Temozolomide Era: A Meta-Analysis. ( Burns, TC; Chaichana, KL; Goyal, A; Graffeo, CS; Lu, VM; Parney, IF; Perry, A; Quinones-Hinojosa, A, 2019)
" For glioblastoma, the irradiation dose of 60 Gy in 30 fractions with concomitant and adjuvant temozolomide is currently considered as a standard of treatment, and further dose escalation has failed to be of benefit in clinical trials."4.98Fractionated Radiotherapy of Intracranial Gliomas. ( Ghia, AJ, 2018)
" Temozolomide, a monofunctional alkylator, was the first chemotherapeutic agent to definitively improve survival in adults with newly diagnosed glioblastoma used in combination with radiation therapy with the most pronounced effect being in a subgroup of tumors with MGMT promoter methylation."4.98Chemotherapy of High-Grade Astrocytomas in Adults. ( Hoang, N; Puduvalli, VK, 2018)
"Temozolomide is the most widely used chemotherapy for patients with glioblastoma (GBM) despite the fact that approximately half of treated patients have temozolomide resistance and all patients eventually fail therapy."4.98Temozolomide for immunomodulation in the treatment of glioblastoma. ( Dastmalchi, F; Karachi, A; Mitchell, DA; Rahman, M, 2018)
"This review focuses on a carotenoid and a phlorotannin present in seaweed, namely fucoxanthin and phloroglucinol, and their anticancer activity against glioblastoma."4.98Drug resistance in glioblastoma and cytotoxicity of seaweed compounds, alone and in combination with anticancer drugs: A mini review. ( Almeida, T; Azqueta, A; Ferreira, J; Ramos, AA; Rocha, E, 2018)
"New therapeutic agents in combination with the standard Stupp protocol (a protocol about the temozolomide combined with radiotherapy treatment with glioblastoma was research by Stupp R in 2005) were assessed to evaluate whether they were superior to the Stupp protocol alone, to determine the optimum treatment regimen for patients with newly diagnosed glioblastoma."4.95The interventional effect of new drugs combined with the Stupp protocol on glioblastoma: A network meta-analysis. ( Chen, T; Fu, A; Li, J; Li, M; Song, X; Zhu, J, 2017)
"To assess the effectiveness and safety of procarbazine, lomustine, and vincristine (PCV) chemotherapy with other interventions in adults with recurrent high-grade glioma."4.95Procarbazine, lomustine and vincristine for recurrent high-grade glioma. ( Guo, J; Parasramka, S; Rosenfeld, M; Talari, G; Villano, JL, 2017)
"There is a growing body of evidence that carmustine wafer implantation during surgery is an effective therapeutic adjunct to the standard combined radio-chemotherapy regimen using temozolomide in newly diagnosed and recurrent high-grade glioma patient management with a statistically significant survival benefit demonstrated across several randomized clinical trials, as well as prospective and retrospective studies (grade A recommendation)."4.95Carmustine wafer implantation for high-grade gliomas: Evidence-based safety efficacy and practical recommendations from the Neuro-oncology Club of the French Society of Neurosurgery. ( Caire, F; Guyotat, J; Menei, P; Metellus, P; Pallud, J; Roux, A, 2017)
"Tumor treating fields (TTFields) are an integral treatment modality in the management of glioblastoma and extend overall survival when combined with maintenance temozolomide in newly diagnosed patients."4.95A state-of-the-art review and guidelines for tumor treating fields treatment planning and patient follow-up in glioblastoma. ( Battiste, J; Bota, DA; Connelly, J; Damek, D; Dunbar, E; Iwamoto, F; Mohile, N; Trusheim, J, 2017)
"The current meta-analysis evaluated the survival outcomes of newly diagnosed glioblastoma patients treated with radiotherapy (RT) alone and with RT + temozolomide (TMZ)."4.95Temozolomide with or without Radiotherapy in Patients with Newly Diagnosed Glioblastoma Multiforme: A Meta-Analysis. ( Feng, E; Sui, C; Sun, G; Wang, T, 2017)
"Since 2005, the standard of care for patients with newly diagnosed glioblastoma (GBM) has consisted of maximal resection followed by radiotherapy plus daily temozolomide (TMZ), followed by maintenance TMZ."4.95Critical review of the addition of tumor treating fields (TTFields) to the existing standard of care for newly diagnosed glioblastoma patients. ( Mehta, M; Nishikawa, R; Peters, K; Reardon, D; Wen, P, 2017)
"Malignant gliomas are highly invasive tumors, associated with a dismal survival rate despite standard of care, which includes surgical resection, radiotherapy and chemotherapy with temozolomide (TMZ)."4.95Single vs. combination immunotherapeutic strategies for glioma. ( Asad, AS; Candolfi, M; Castro, MG; Chandran, M; Koschmann, C; Lowenstein, PR; Mineharu, Y; Shah, D; Yadav, VN, 2017)
"In the last decade, phase III trials on novel compounds largely failed to introduce efficacious pharmacotherapies beyond temozolomide in glioblastoma."4.93Pharmacotherapies for the treatment of glioblastoma - current evidence and perspectives. ( Gramatzki, D; Roth, P; Seystahl, K; Weller, M, 2016)
"This review article summarizes in vitro, in vivo, and clinical evidence pertaining to temozolomide (TMZ) and bevacizumab (BEV) efficacy and mechanism of action in gliomas."4.91Current evidence of temozolomide and bevacizumab in treatment of gliomas. ( Chattipakorn, N; Chattipakorn, SC; Nanegrungsunk, D; Onchan, W, 2015)
"Temozolomide is the current standard of therapy for postoperative patients with glioblastoma starting adjuvant radiotherapy."4.91Severe cholestatic hepatitis due to temozolomide: an adverse drug effect to keep in mind. Case report and review of literature. ( Balducci, N; Biolato, M; Di Napoli, N; Diletto, B; Grieco, A; Miele, L; Tafuri, MA; Vecchio, FM, 2015)
"Long-term temozolomide might be an optimal choice for patients with multifocal glioblastoma, especially with deep-seated structure involvement."4.91Long-term temozolomide might be an optimal choice for patient with multifocal glioblastoma, especially with deep-seated structure involvement: a case report and literature review. ( Gao, Z; Hao, S; Liu, Y; Yu, L, 2015)
"The Avastin in Glioblastoma trial has shown that patients newly diagnosed with glioblastoma multiforme (GBM) treated with bevacizumab plus radiotherapy and temozolomide versus radiotherapy and temozolomide alone showed improvement in progression-free survival, possibly leading to a new indication for first-line use of bevacizumab in GBM."4.91Economic Evaluation of Bevacizumab for the First-Line Treatment of Newly Diagnosed Glioblastoma Multiforme. ( Kovic, B; Xie, F, 2015)
"The goal of this meta-analysis was to identify the temozolomide (TMZ) regimen with optimal efficacy and tolerance for treatment of recurrent high-grade glioma (HGG)."4.91The efficacy and safety of various dose-dense regimens of temozolomide for recurrent high-grade glioma: a systematic review with meta-analysis. ( Chen, X; Guo, Z; Ma, X; Wang, D; Wei, W, 2015)
" The authors hereby, evaluated the use of temozolomide (TMZ) for treating metastatic melanoma compared to dacarbazine (DTIC), the effectiveness of TMZ for treating brain metastases, as well as TMZ resistance and how the efficacy of TMZ in malignant melanoma can be increased."4.91Temozolomide for Treating Malignant Melanoma. ( Hou, XY; Jiang, G; Li, RH; Liu, WL; Liu, YQ; Tang, JQ; Yang, CS, 2015)
"Anaplastic oligodendrogliomas (AOs) are rare brain tumors responsive to chemotherapy with procarbazine, lomustine (CCNU) and vincristine (PCV), especially when harboring 1p19q codeletion."4.91Procarbazine, lomustine and vincristine or temozolomide: which is the better regimen? ( Lassman, AB, 2015)
"Temozolomide (TMZ) alone has been proposed as a promising alternative to radiotherapy (RT) in elderly glioblastoma (GBM) patients."4.90A meta-analysis of temozolomide versus radiotherapy in elderly glioblastoma patients. ( Cai, S; Cheng, JX; Dong, Y; Liu, BL; Yin, AA; Zhang, LH; Zhang, X, 2014)
"Postoperative external beam radiotherapy was considered the standard adjuvant treatment for patients with glioblastoma multiforme until the advent of using the drug temozolomide (TMZ) in addition to radiotherapy."4.90Radiation and concomitant chemotherapy for patients with glioblastoma multiforme. ( Balañà, C; Comas, S; Villà, S, 2014)
"Temozolomide is recommended as superior to procarbazine in patients with first relapse of glioblastoma after having received nitrosourea chemotherapy or no prior cytotoxic chemotherapy at the time of initial therapy."4.90The role of cytotoxic chemotherapy in the management of progressive glioblastoma : a systematic review and evidence-based clinical practice guideline. ( Kalkanis, SN; Nayak, L; Olson, JJ; Ormond, DR; Wen, PY, 2014)
" While temozolomide, an alkylating agent, has demonstrated a survival benefit, median survival in the past decade of patients with glioblastoma (GBM) remains an obdurate 15 months and add-on therapies have not significantly prolonged life."4.90Molecular neuro-oncology and the challenge of the blood-brain barrier. ( Aiken, R, 2014)
"Glioblastoma is the most common primary malignant brain tumor, but despite multimodal treatment with surgery, radiotherapy, and temozolomide chemotherapy, the prognosis is poor, with a median survival of 16 to 19 months and poor quality of life throughout the disease course."4.90Emerging therapies for glioblastoma. ( Brennan, CW; DeAngelis, LM; Omuro, AM; Thomas, AA, 2014)
"This analysis was conducted to evaluate the efficacy and safety of temozolomide based chemotherapy in treating patients with glioma."4.90Comprehensive analysis of temozolomide treatment for patients with glioma. ( Liang, H; Xing, BZ; Yang, WB, 2014)
"For primary therapy three RCTs were identified, enrolling a total of 745 patients, that investigated temozolomide in combination with radiotherapy versus radiotherapy alone for glioblastoma multiforme (GBM)."4.89Temozolomide for high grade glioma. ( Garside, R; Grant, R; Hart, MG; Rogers, G; Stein, K, 2013)
"Temozolomide (TMZ) is an alkylating agent currently used as first-line therapy for gliomas treatment due to its DNA-damaging effect."4.89O6-methylguanine DNA methyltransferase as a promising target for the treatment of temozolomide-resistant gliomas. ( Cao, H; Chen, L; Fan, CH; Jiang, G; Liu, WL; Wen, C, 2013)
"The efficacy of temozolomide (TMZ) in recurrent glioblastoma multiforme (GBM) has been evaluated by several clinical trials."4.89The efficacy of temozolomide for recurrent glioblastoma multiforme. ( Chen, C; Chen, J; Lu, Y; Wu, S; Xu, T, 2013)
"We searched three online databases to systematically identify publications testing temozolomide in animal models of glioma."4.89Systematic review and meta-analysis of temozolomide in animal models of glioma: was clinical efficacy predicted? ( Egan, KJ; Hirst, TC; Macleod, MR; Sena, ES; Vesterinen, HM; Whittle, IR, 2013)
"The landmark Stupp study demonstrated a survival advantage with concomitant and adjuvant temozolomide (TMZ) with standard radiotherapy (RT) in glioblastoma multiforme (GBM) patients but excluded those older than 70 years."4.88Hypofractionated radiotherapy with or without concurrent temozolomide in elderly patients with glioblastoma multiforme: a review of ten-year single institutional experience. ( Bauman, GS; Cao, JQ; Fisher, BJ; Macdonald, DR; Megyesi, JF; Watling, CJ, 2012)
"This article provides historical and recent perspectives related to the use of temozolomide for the treatment of glioblastoma multiforme."4.88Temozolomide and other potential agents for the treatment of glioblastoma multiforme. ( Chow, F; Cremer, N; Kim, W; Nagasawa, DT; Yang, I; Yew, A, 2012)
" Attempted gross total surgical resection followed by concurrent temozolomide and radiation therapy has become standard of care for glioblastoma."4.88Potential usefulness of radiosensitizers in glioblastoma. ( Harasaki, Y; Waziri, A, 2012)
"Glioblastoma is a brain tumor with poor prognosis in the therapy of which operation, postoperative temozolomide sensitized radiochemotherapy followed by temozolomide monotherapy offer the best chances."4.88[Use of angioneogenesis inhibitor monoclonal antibody following standard therapy in recurrent or progressive glioblastoma multiforme]. ( Bassam, A; Nagy, KA; Pikó, B; Puskásné Szatmári, K; Török, E; Vághy, R; Vargáné Tamás, R, 2012)
"In patients with glioblastoma multiforme (GBM), there is no consensus on the sequential use of two existing regimens: post-operative Gliadel implantation into the surgical cavity and concomitant temozolomide with radiotherapy followed by adjuvant temozolomide ('Stupp protocol')."4.87The sequential use of carmustine wafers (Gliadel®) and post-operative radiotherapy with concomitant temozolomide followed by adjuvant temozolomide: a clinical review. ( Achawal, S; Dixit, S; Hingorani, M; Scott, I, 2011)
"The standard therapy for newly diagnosed malignant gliomas comprises surgery, radiotherapy, and commonly temozolomide chemotherapy."4.87An algorithm for chemotherapy treatment of recurrent glioma patients after temozolomide failure in the general oncology setting. ( Kyritsis, AP; Levin, VA, 2011)
"Loco-regional chemotherapy with carmustine wafers (Gliadel) positioned at surgery and followed by radiotherapy has been shown to prolong survival in first-diagnosis glioblastoma, as well as concomitant radiochemotherapy with temozolomide."4.87Loco-regional treatments in first-diagnosis glioblastoma: literature review on association between Stupp protocol and Gliadel. ( Casali, C; Di Meco, F; Duri, S; Gaviani, P; Milanesi, I; Salmaggi, A; Silvani, A, 2011)
"Temozolomide-based chemotherapy represents an incremental improvement in the treatment of patients with high-grade gliomas."4.86Temozolomide: therapeutic limitations in the treatment of adult high-grade gliomas. ( Chamberlain, MC, 2010)
"One barrier to successful treatment of malignant glioma is resistance to alkylating agents such as temozolomide."4.85New (alternative) temozolomide regimens for the treatment of glioma. ( Platten, M; Weller, M; Wick, W, 2009)
" The standard care for glioblastoma is surgery and concomitant radio- and chemotherapy with temozolomide (TMZ), followed by adjuvant treatment with TMZ."4.85Insights into pharmacotherapy of malignant glioma in adults. ( D'Elia, A; Formichella, AI; Frati, A; Salvati, M, 2009)
"Temozolomide (TMZ) offers substantial therapeutic benefits for glioblastoma (GB), yet its efficacy is hindered the development of chemoresistance."4.84CREB-induced LINC00473 promotes chemoresistance to TMZ in glioblastoma by regulating O6-methylguanine-DNA-methyltransferase expression via CEBPα binding. ( Fang, X; Feng, M; Jiang, CM; Jiang, LY; Li, XL; Lin, XY; Wang, GH; Xu, JJ; Zhang, HX, 2024)
"In primary disease two RCTs were identified, enrolling a total of 703 patients, that investigated concomitant and adjuvant temozolomide in Glioblastoma Multiforme (GBM)."4.84Temozolomide for high grade glioma. ( Garside, R; Grant, R; Hart, MG; Rogers, G; Somerville, M; Stein, K, 2008)
"Patients with brain metastasis were identified from 3 prospective studies of temozolomide (with or without immunotherapy) for metastatic melanoma."4.84Temozolomide in advanced malignant melanoma with small brain metastases: can we withhold cranial irradiation? ( Boogerd, W; Dalesio, O; de Gast, GC, 2007)
"Carmustine wafers (Gliadel) and temozolomide (Temodal) were recently approved for initial management of glioblastoma."4.84[What type of adjuvant chemotherapy should be proposed for the initial treatment of glioblastoma?]. ( Ducray, F; Honnorat, J, 2007)
" Temozolomide is a novel second-generation alkylating agent that has shown efficacy for the treatment of high-grade gliomas."4.84[Glioma therapy up-date]. ( Dalmau, J; de la Fuente, BP; Rosenfeld, M, 2007)
"The dismal prognosis of glioblastoma had remained unchanged for the past 30 years until the association of temozolomide and radiotherapy in the breakthrough European Organization for Cancer/National Cancer Institute of Canada (EORTC/NCIC) trial brought new hope for patients."4.83The evolution of chemoradiation for glioblastoma: a modern success story. ( Mirimanoff, RO, 2006)
"Following the seminal trial conducted by the European Organisation for Research and Treatment of Cancer (EORTC) and the National Cancer Institute of Canada (NCIC), concurrent temozolomide and radiotherapy has become the new standard of care for patients with newly diagnosed glioblastoma multiforme (GBM)."4.83Treatment options for glioblastoma. ( Chamberlain, MC, 2006)
"Concomitant and adjuvant treatment with Temozolomide, an oral alkylating agent, has significantly improved the survival of patients with newly diagnosed glioblastoma multiforme (study EORTC 26981/22981, NCIC CE3)."4.83Chemotherapy for malignant gliomas. ( Marosi, C, 2006)
"Surgery and radiation have been the mainstays of therapy for most glioma patients, but temozolomide chemotherapy has recently been proven to prolong overall survival in patients with glioblastoma."4.83Glioma therapy in adults. ( Norden, AD; Wen, PY, 2006)
"The current standard of care for malignant gliomas is surgical resection and radiotherapy followed by extended adjuvant treatment with the alkylating agent temozolomide."4.83Oncolytic viruses and DNA-repair machinery: overcoming chemoresistance of gliomas. ( Alonso, MM; Fueyo, J; Gomez-Manzano, C; Jiang, H; Piao, Y, 2006)
" The place of chemotherapy is growing not only for anaplastic oligodendrogliomas, more chemosensitive (particularly when they harbor 1p19q codeletions), but also for glioblastomas patients, which have been shown to benefit from radiotherapy plus concomitant and adjuvant temozolomide."4.83[Pattern of care of high-grade gliomas]. ( Laigle-Donadey, F; Sanson, M, 2006)
" We report a 44-year-old woman with t-MDS (refractory anemia with excess blasts) following treatment of recurrent anaplastic astrocytoma with temozolomide (TMZ)."4.82Treatment-related myelodysplastic syndrome after temozolomide for recurrent high-grade glioma. ( Chang, MC; Chiang, MF; Hsieh, RK; Su, YW, 2005)
" In this paper we address different clinical outcomes measures separately and we illustrate the value of multiple outcome measures using the results of a recent clinical trial comparing temozolomide with procarbazine in the treatment of Glioblastoma Multiforme."4.82Benefit of temozolomide compared to procarbazine in treatment of glioblastoma multiforme at first relapse: effect on neurological functioning, performance status, and health related quality of life. ( Kiebert, G; Macdonald, DR; Olson, J; Prados, M; Yung, A, 2005)
" Temozolomide, an alkylating agent that can be administered orally, has been approved for the treatment of recurrent malignant glioma on a daily schedule for 5-day cycles."4.81Current and future developments in the use of temozolomide for the treatment of brain tumours. ( Gander, M; Leyvraz, S; Newlands, E; Stupp, R, 2001)
"Temozolomide (TMZ) is a new, orally administered, second-generation imidazotetrazine prodrug with essentially 100% oral bioavailability that has demonstrated meaningful efficacy and an acceptable safety profile in the treatment of patients with recurrent glioblastoma multiforme."4.80Future directions in the treatment of malignant gliomas with temozolomide. ( Prados, MD, 2000)
"Temozolomide (TMZ) has been used as standard-of-care for glioblastoma multiforme (GBM), but the resistance to TMZ develops quickly and frequently."4.31Involvement of cell shape and lipid metabolism in glioblastoma resistance to temozolomide. ( An, YJ; Choo, M; Kim, DH; Kim, HS; Ku, JL; Lee, SK; Mai, VH; Park, CK; Park, S, 2023)
"Temozolomide (TMZ) is the recommended drug for glioblastoma (GBM) treatment, but its clinical effect is restricted due to drug resistance."4.31Implication of lncRNA ZBED3-AS1 downregulation in acquired resistance to Temozolomide and glycolysis in glioblastoma. ( Dong, J; Jiang, Z; Peng, Y; Wang, K; Wu, Y; Xie, Z; Zhong, M, 2023)
"Temozolomide (TMZ) has been determined to be the chemotherapeutic drug with efficacy for glioblastoma (GBM)."4.31Ultrasound-excited temozolomide sonosensitization induces necroptosis in glioblastoma. ( Song, S; Tong, X; Wang, F; Wang, Y; Wen, B; Wu, H; Wu, Q; Xu, L; Yan, H; Zhou, Y, 2023)
"Complete resection of glioblastoma via a supraorbital transciliary approach with 5-Aminolevulinic Acid use was performed without any complications, as demonstrated on postoperative MRI."4.31Supraorbital transciliary approach as primary route to fronto-basal high grade glioma resection with 5-Aminolevulinic Acid use: Technical note. ( Aboukaïs, R; Bourgeois, P; Devalckeneer, A; Lejeune, JP; Reyns, N, 2023)
" Based on CRISPR-Cas9 library screening, we found that mucin1 (MUC1) is essential for EGFRvIII glioma cell survival and temozolomide (TMZ) resistance."4.31MUC1 promotes glioblastoma progression and TMZ resistance by stabilizing EGFRvIII. ( Cui, XT; Fang, ZY; Fu, JQ; Kang, CS; Liu, SZ; Liu, X; Qiu, ZJ; Su, DY; Tong, F; Wang, GX; Wang, JC; Wang, QX; Zhao, JX; Zhou, JH, 2023)
"Temozolomide (TMZ) is a conventional chemotherapeutic drug for glioma, however, its clinical application and efficacy is severely restricted by its drug resistance properties."4.31The nanoprodrug of polytemozolomide combines with MGMT siRNA to enhance the effect of temozolomide in glioma. ( Li, L; Liu, H; Ma, H; Qian, F; Quan, A; Ren, Y; Wang, L; Xu, H; Yu, R; Zhang, Y, 2023)
"Temozolomide (TMZ) delivery was investigated in CT2A and PDGFB-driven RCAS/tv-a orthotopic glioma models."4.31Wnt signaling regulates MFSD2A-dependent drug delivery through endothelial transcytosis in glioma. ( Cao, H; Chao, M; Dimberg, A; He, L; Huang, H; Li, Y; Shi, X; Tang, J; Uhrbom, L; Wang, J; Wang, L; Xiao, B; Xie, Y; Xin, L; Yang, F; Zhang, L; Zhang, X; Zhang, Y, 2023)
" In this study, we investigated the role of KDM1A/LSD1 in DNA double-strand break (DSB) repair and a combination of KDM1A inhibitor and temozolomide (TMZ) in vitro and in vivo using patient-derived glioma stem cells (GSCs)."4.31Lysine-specific histone demethylase 1A (KDM1A/LSD1) inhibition attenuates DNA double-strand break repair and augments the efficacy of temozolomide in glioblastoma. ( Alejo, S; Brenner, AJ; Chen, Y; Clarke, K; Gilbert, AR; He, Y; Jayamohan, S; Johnson, JD; Lai, Z; Li, W; Lv, Y; Palacios, BE; Pratap, UP; Sareddy, GR; Suzuki, T; Tekmal, RR; Vadlamudi, RK; Venkata, PP; Viswanadhapalli, S; Weldon, K; Ye, Z; Zhao, W; Zheng, S; Zou, Y, 2023)
"Hypofractionated radiotherapy (HypoRT) has recently been implemented in patients with glioblastoma (GBM) receiving concurrent temozolomide."4.31Clinical Outcomes of Moderately Hypofractionated Concurrent Chemoradiotherapy for Newly Diagnosed Glioblastoma. ( Choi, JW; Kim, N; Kong, DS; Lee, JI; Lim, DH; Nam, DH; Seol, HJ, 2023)
"Our study aimed to assess the benefit of prolonging adjuvant temozolomide (TMZ) therapy beyond 6 cycles in glioblastoma multiform patients."4.31Impact of Extended Adjuvant Temozolamide Beyond 6 Months in the Management of Glioblastoma Patients. ( Elsaid, AA; Elsaka, R; Kitagwa, JM; Mahmoud, AA; Meheissen, MAM; Refaat, T; Shaikh, H, 2023)
"Although temozolomide (TMZ) provides significant clinical benefit for glioblastoma (GBM), responses are limited by the emergence of acquired resistance."4.31Exosome-transmitted circCABIN1 promotes temozolomide resistance in glioblastoma via sustaining ErbB downstream signaling. ( Cao, Z; Gao, G; Gu, J; Guan, Z; Guo, Q; Hao, Q; Jia, B; Li, M; Li, W; Liu, X; Wang, S; Wang, W; Zhang, K; Zhang, W; Zhang, Y, 2023)
"The development of resistance to temozolomide (TMZ), a standard chemotherapeutic, limits the effective treatment of glioblastoma (GBM)."4.31The PYK2 inhibitor PF-562271 enhances the effect of temozolomide on tumor growth in a C57Bl/6-Gl261 mouse glioma model. ( Kucheryavykh, L; Kucheryavykh, Y; Nuñez, R; Ortiz-Rivera, J, 2023)
" We aimed to clarify the interplay between purinergic signaling and chemotherapeutic drug temozolomide (TMZ) in human glioma cell line."4.31Purinergic approach to effective glioma treatment with temozolomide reveals enhanced anti-cancer effects mediated by P2X7 receptor. ( Czach, S; Czarnecka, J; Nowak, W; Roszek, K; Szymczak, B, 2023)
"Although temozolomide (TMZ) has been used as a standard adjuvant chemotherapeutic agent for primary glioblastoma (GBM), treating isocitrate dehydrogenase wild-type (IDH-wt) cases remains challenging due to intrinsic and acquired drug resistance."4.31Pharmacogenomic profiling reveals molecular features of chemotherapy resistance in IDH wild-type primary glioblastoma. ( Cho, HJ; Choi, SW; Kim, D; Kim, Y; Kong, DS; Koo, H; Kwon, YJ; Lee, HW; Lee, JI; Lee, K; Mu, Q; Nam, Y; Oh, JW; Park, CK; Park, WY; Sa, JK; Seo, YJ; Seol, HJ; Shin, S; Wang, J; Yang, Y; Yoon, Y; Zhu, Z, 2023)
"Temozolomide (TMZ) is one of the best choices for treating glioblastoma."4.31Exploring temozolomide encapsulated PEGylated liposomes and lyotropic liquid crystals for effective treatment of glioblastoma: in-vitro, cell line, and pharmacokinetic studies. ( Laxmi Swetha, K; Narayan Saha, R; Roy, A; Singhvi, G; Waghule, T, 2023)
"Temozolomide (TMZ) is the preferred chemotherapy strategy for glioma therapy."4.31Gut microbiota mediated the individualized efficacy of Temozolomide via immunomodulation in glioma. ( Deng, Y; Du, H; Hou, X; Liu, J; Liu, W; Liu, Y; Qiao, J; Shu, X; Sun, B; Wang, H, 2023)
" Protein disulfide isomerase (PDI) is a molecular chaperone known to be highly expressed in glioblastomas with acquired resistance to temozolomide (TMZ)."4.31Targeting unfolded protein response using albumin-encapsulated nanoparticles attenuates temozolomide resistance in glioblastoma. ( Kiang, KM; Lam, TL; Leung, GK; Li, N; Liu, J; Shum, HC; Song, Q; Tang, W; Zhu, Z, 2023)
"The chemoresistance of temozolomide-based therapy is a serious limitation for lasting effective treatment of gliomas, while the underlying mechanisms remain unclear."4.31Downregulation of BASP1 Promotes Temozolomide Resistance in Gliomas via Epigenetic Activation of the FBXO32/NF-κB/MGMT Axis. ( Chen, S; Li, J; Li, M; Li, X; Li, Z; Liao, X; Qian, W; Song, L; Tang, M; Xu, Y; Yu, R; Zhang, S; Zheng, H, 2023)
"Temozolomide (TMZ)-based chemotherapy plays a central part in glioma treatment."4.31SRSF4 Confers Temozolomide Resistance of Glioma via Accelerating Double Strand Break Repair. ( Liu, X; Sun, Y; Wang, X; Wu, Z; Yan, W; You, Y; Zhang, Y, 2023)
" TTFields therapy is approved for treatment of newly-diagnosed glioblastoma (GBM) concurrent with maintenance temozolomide (TMZ)."4.31Tumor Treating Fields (TTFields) increase the effectiveness of temozolomide and lomustine in glioblastoma cell lines. ( Dor-On, E; Fishman, H; Giladi, M; Haber, A; Kinzel, A; Monin, R; Palti, Y; Weinberg, U, 2023)
"Glioblastoma (GBM) is a malignant brain tumor, commonly treated with temozolomide (TMZ)."4.31ADAM17 Confers Temozolomide Resistance in Human Glioblastoma Cells and miR-145 Regulates Its Expression. ( Chen, JC; Chong, ZY; Huang, C; Huang, HC; Lee, IN; Wu, YP; Yang, JT, 2023)
"Patients with glioblastoma (GBM) have poor prognosis and limited therapeutic options, largely because of chemoresistance to temozolomide (TMZ) treatment."4.31UBE2T Promotes Temozolomide Resistance of Glioblastoma Through Regulating the Wnt/β-Catenin Signaling Pathway. ( Gao, G; Wang, Y; Wei, X; Yu, J; Zhang, Y, 2023)
"This study aims to elucidate the mechanism underlying temozolomide resistance in patients with MGMT promoter hypomethylated glioblastoma, which is correlated with poor prognosis."4.31AHR, a novel inhibitory immune checkpoint receptor, is a potential therapeutic target for chemoresistant glioblastoma. ( Bian, Y; Li, P; Li, S; Liu, J; Liu, Z; Pan, J; Song, S; Sun, Z; Tan, N; Wang, Y; Zhao, W, 2023)
"Temozolomide resistance remains a major obstacle in the treatment of glioblastoma (GBM)."4.31The DRD2 Antagonist Haloperidol Mediates Autophagy-Induced Ferroptosis to Increase Temozolomide Sensitivity by Promoting Endoplasmic Reticulum Stress in Glioblastoma. ( Chen, H; Chen, K; Chen, L; Huang, A; Huang, Y; Li, C; Li, H; Lu, Y; Qi, S; Shi, L; Song, C; Wang, T; Zhong, C, 2023)
"Chemoresistance blunts the efficacy of temozolomide (TMZ) in the treatment of glioblastoma (GBM)."4.31Resveratrol Enhances Temozolomide Efficacy in Glioblastoma Cells through Downregulated MGMT and Negative Regulators-Related STAT3 Inactivation. ( Ahmad, N; Cheng, X; Deng, S; Li, H; Shu, X; Song, D; Wang, Q; Wu, M; Xu, H; Yang, X, 2023)
"Glioblastoma multiforme (GBM) is the deadliest glioma and its resistance to temozolomide (TMZ) remains intractable."4.31HOXD-AS2-STAT3 feedback loop attenuates sensitivity to temozolomide in glioblastoma. ( Cao, YY; Chen, JX; Chen, QZ; Huang, GH; Li, Y; Liu, GL; Lv, SQ; Pei, YC; Ren, P; Wang, TT; Xiang, Y; Yang, L; Yang, W; Zhang, ZX; Zhou, S, 2023)
"Dacarbazine is an important drug in the therapeutic landscape of leiomyosarcoma (LMS)."4.31The Impact of O6-Methylguanine-DNA Methyltransferase ( ( Badalamenti, G; Barretta, ML; Buonaiuto, M; Cannella, L; Chiariotti, L; Clemente, O; De Chiara, AR; Della Monica, R; Di Marzo, M; Di Mauro, A; Guida, M; Iervolino, D; Marretta, AL; Tafuto, S; Vincenzi, B, 2023)
"The standard treatment of glioblastoma, an aggressive brain tumour, includes radiotherapy combined with temozolomide."4.31[Regional variation in usage of TTF (Optune)]. ( Henriksson, R; Kinhult, S; Löfgren, D; Rosenlund, L; Sandström, M; Strandeus, M; Tavelin, B, 2023)
"Temozolomide (TMZ) is considered a first line chemotherapy drug for glioblastoma (GBM)."4.31Label-Free Raman Spectromicroscopy Unravels the Relationship between MGMT Methylation and Intracellular Lipid Accumulation in Glioblastoma. ( Ji, N; Wang, J; Wang, N; Wang, P; Yue, S, 2023)
"The potential targets and mechanisms of quercetin in glioma treatment were predicted based on network pharmacology and molecular docking."4.31Quercetin induces MGMT ( Chen, J; Li, B; Mu, J; Wang, Q; Wang, W; Wu, X; Xu, L; Yin, Z; Yuan, X; Zeng, Z; Zhu, X; Zou, Y, 2023)
"In our study, we included 169 glioblastoma patients who were admitted to our clinic between 2009 and 2019 and received concurrent radiotherapy (RT) + temozolomide (TMZ) after surgery."4.31The Assessment of Clinical Outcomes and Prognostic Factors in Glioblastoma Patients. ( Bora, H; Demircan, NV; Erpolat, OP; Guzel, C; Karahacioglu, E; Senturk, E, 2023)
"To explore the role of forkhead box protein O1 (FOXO1) in the progression of glioblastoma multiforme (GBM) and related drug resistance, we deciphered the roles of FOXO1 and miR-506 in proliferation, apoptosis, migration, invasion, autophagy, and temozolomide (TMZ) sensitivity in the U251 cell line using in vitro and in vivo experiments."4.31FOXO1-miR-506 axis promotes chemosensitivity to temozolomide and suppresses invasiveness in glioblastoma through a feedback loop of FOXO1/miR-506/ETS1/FOXO1. ( Chen, C; Chen, J; Liu, Y; Shi, Y; Wang, H; Zhang, X, 2023)
"The cytotoxic effects of shikonin against murine glioblastoma cells, SB28 and CT-2A, were reported resistance to temozolomide, were evaluated using an allophycocyanin-conjugated annexin V and propidium iodide assay with flow cytometry."4.31Local administration of shikonin improved the overall survival in orthotopic murine glioblastoma models with temozolomide resistance. ( Maeoka, R; Matsuda, R; Morimoto, T; Nakagawa, I; Nakase, H; Nakazawa, T; Nishimura, F; Ouji, Y; Park, YS; Yamada, S; Yokoyama, S; Yoshikawa, M, 2023)
"To report the long-term outcomes in adult patients with grade 2 IDH-mutant astrocytoma treated with temozolomide (TMZ)-based chemoradiation."4.31Long-term treatment outcomes of temozolomide-based chemoradiation in patients with adult-type diffuse IDH-mutant grade 2 astrocytoma. ( Antonelli, M; Arcella, A; Bozzao, A; Capone, L; De Pietro, R; Esposito, V; Gianno, F; Giraffa, M; Lanzetta, G; Minniti, G; Paolini, S; Romano, A; Tini, P, 2023)
"In our previous study, we found for the first time that temozolomide (TMZ), the first-line chemotherapeutic agent for glioblastoma (GBM), can generate a large amount of reactive oxygen species (ROS) under ultrasound irradiation."4.31Temozolomide-based sonodynamic therapy induces immunogenic cell death in glioma. ( Jiao, J; Tong, X; Wen, B; Wu, Q; Xu, L; Yan, H; Yang, R; Zhou, Y, 2023)
"In the randomized CeTeG/NOA-09 trial, lomustine/temozolomide (CCNU/TMZ) was superior to TMZ therapy regarding overall survival (OS) in MGMT promotor-methylated glioblastoma."4.31Undetected pseudoprogressions in the CeTeG/NOA-09 trial: hints from postprogression survival and MRI analyses. ( Duffy, C; Galldiks, N; Glas, M; Goldbrunner, R; Grauer, O; Hattingen, E; Hau, P; Herrlinger, U; Krex, D; Nitsch, L; Paech, D; Potthoff, AL; Radbruch, A; Schäfer, N; Schaub, C; Schlegel, U; Schneider, M; Seidel, C; Steinbach, JP; Stummer, W; Tabatabai, G; Tzaridis, T; Weller, J; Zeiner, PS; Zeyen, T, 2023)
"Temozolomide (TMZ) is a commonly used chemotherapeutic agent for glioblastoma (GBM), but acquired drug resistance prevents its therapeutic efficacy."4.31NFYB increases chemosensitivity in glioblastoma by promoting HDAC5-mediated transcriptional inhibition of SHMT2. ( Huang, H; Liu, P; Xie, Y; Zhang, Y, 2023)
"To investigate the effect of Temozolomide combined with intensity modulated radiation therapy on serum factor, immune function and clinical efficacy in postoperative glioma patients."4.31Effect of Temozolomide Combined with Intensity Modulated Radiation Therapy on Serum Factor, Immune Function and Clinical Efficacy in Postoperative Glioma Patients. ( Fan, R; Liu, J; Liu, Z; Yuan, J, 2023)
"Altogether, our results indicate that using nanoemulsion containing temozolomide in combination with ferrocene is an effective approach to improve glioblastoma therapy outcomes."4.31Development and characterization of a temozolomide-loaded nanoemulsion and the effect of ferrocene pre and co-treatments in glioblastoma cell models. ( Bernardes Ferro, M; da Rosa, RG; da Silva, LF; de Oliveira, JVR; de Souza, BM; Henn, JG; Lopes Alves, GA; Morás, AM; Moura, DJ; Nugent, M; Pires Peña, F; Rapack Jacinto Silva, V; Silva Pinheiro, AC; Silveira Aguirre, TA; Steffens Reinhardt, L, 2023)
"Temozolomide (TMZ) treatment efficacy in glioblastoma (GBM) patients has been limited by resistance in the clinic."4.31Albumin-bound paclitaxel augment temozolomide treatment sensitivity of glioblastoma cells by disrupting DNA damage repair and promoting ferroptosis. ( Huang, G; Li, Z; Qi, S; Qu, S; Wang, K; Ye, R; Yi, GZ; Zhang, H; Zhang, W; Zhu, T, 2023)
"To explore the mechanism through which curcumol reverses primary drug resistance in glioma cells."4.31[Curcumol reverses temozolomide resistance in glioma cells by regulating the UTX/MGMT axis]. ( Qian, Y; Sun, J; Tan, R; Tian, N; Xing, J, 2023)
"The therapeutic options for metastatic pheochromocytomas/paragangliomas (mPPGLs) include chemotherapy with cyclophosphamide/vincristine/dacarbazine (CVD), temozolomide monotherapy, radionuclide therapies, and tyrosine kinase inhibitors such as sunitinib."4.31Responses to systemic therapy in metastatic pheochromocytoma/paraganglioma: a retrospective multicenter cohort study. ( Auernhammer, CJ; Bechmann, N; Beuschlein, F; Bornstein, SR; Dischinger, U; Fischer, A; Fliedner, SMJ; Grossman, AB; Hantel, C; Kloos, S; Kroiss, M; Maurer, J; Mohr, H; Nölting, S; Pacak, K; Pamporaki, C; Pellegata, NS; Reincke, M; Remde, H; Reul, A; Robledo, M; Timmers, HJLM; Wang, K, 2023)
"Chemotherapy using temozolomide is the standard treatment for patients with glioblastoma."4.31Genomic Exploration of Distinct Molecular Phenotypes Steering Temozolomide Resistance Development in Patient-Derived Glioblastoma Cells. ( Arijs, I; Beerens, C; Biswas, A; Byrne, AT; Chien, MP; Connor, K; Dilcan, G; Fabro, F; Feller, KJ; Idbaih, A; Kers, TV; Kremer, A; Lambrechts, D; Lamfers, MLM; Leenstra, S; Lodi, F; Ntafoulis, I; O'Farrell, AC; Prehn, JHM; Salvucci, M; Tching Chi Yen, R; Verreault, M, 2023)
"Low-grade gliomas are primary brain tumors that arise from glial cells and are usually treated with temozolomide (TMZ) as a chemotherapeutic option."4.31Overcoming chemotherapy resistance in low-grade gliomas: A computational approach. ( Ayala-Hernández, LE; Bosque, JJ; Chulián, S; Delobel, T; García-Ferrer, M; Murek, M; Pérez-Beteta, J; Pérez-García, VM; Piñero, P; Schucht, P, 2023)
"In this study, to screen for candidate markers of temozolomide (TMZ) resistance in glioblastoma, we artificially established TMZ drug-resistant glioblastoma (GBM) cell lines, U251-TMZ and U87-TMZ."4.31Identification of potential glioma drug resistance target proteins based on ultra-performance liquid chromatography-mass spectrometry differential proteomics. ( Bian, L; Li, D; Li, K; Lin, B; Liu, X; Xi, Z; Yan, J; Yang, Q, 2023)
"Hematological adverse events (HAEs) are common during treatment for glioblastoma (GBM), usually associated with temozolomide (TMZ)."4.12Hematological adverse events in the management of glioblastoma. ( Butts, AR; Garcia, CR; Jayswal, R; Morgan, RM; Myint, ZW; Villano, JL; Wang, C; Weiss, HL, 2022)
"Survival of patients with glioblastoma (GBM) increased in the 2000s, most prominently after the addition of temozolomide to the standard-of-care treatment protocol."4.12Temporal Trends in Glioblastoma Survival: Progress then Plateau. ( Carabenciov, ID; Johnson, DR; Neth, BJ; Ruff, MW, 2022)
"The standard treatment of glioblastoma patients consists of surgery followed by normofractionated radiotherapy (NFRT) with concomitant and adjuvant temozolomide chemotherapy."4.12Accelerated hyper-versus normofractionated radiochemotherapy with temozolomide in patients with glioblastoma: a multicenter retrospective analysis. ( Ehret, F; Grosu, AL; Kaul, D; Klement, RJ; Lewitzki, V; Polat, B; Popp, I; Sweeney, RA, 2022)
" With novel strategies focused on targeting hypoxia-inducible factor (HIF) regulatory pathways, recent evidence has shown that Acriflavine (ACF) can effectively target glioma invasiveness and recurrence."4.12Combined intracranial Acriflavine, temozolomide and radiation extends survival in a rat glioma model. ( Alomari, S; Brem, H; Cecia, A; Darjee, N; Domb, AJ; Gorelick, NL; Mangraviti, A; Rottenberg, Y; Serra, R; Shapira-Furman, T; Tyler, B, 2022)
"Resistance to temozolomide (TMZ) chemotherapy is the main reason for treatment failure in patients with glioblastoma (GBM)."4.12Biochanin A Sensitizes Glioblastoma to Temozolomide by Inhibiting Autophagy. ( Dong, Q; Duan, L; Li, L; Li, Q; Liu, Y; Pan, Y; Wang, D; Wang, J; Wang, X; Yin, H; Yuan, G, 2022)
"The standard of care for elderly glioblastoma patients is 40 Gy in 15 fraction radiotherapy with temozolomide (TMZ)."4.12Dose-escalated accelerated hypofractionation for elderly or frail patients with a newly diagnosed glioblastoma. ( Ammirati, M; Arnett, A; Beyer, S; Blakaj, DM; Brown, PD; Chakravarti, A; Elder, JB; Giglio, P; Gondi, V; Goranovich, J; Grecula, J; Hardesty, D; Klamer, B; Lonser, R; Matsui, J; Ong, S; Palmer, JD; Perlow, HK; Pillainayagam, C; Raval, RR; Yaney, A; Yang, M, 2022)
"Patients with glioblastoma (GBM) are treated with radiotherapy (RT) and temozolomide (TMZ)."4.12Long-Acting Recombinant Human Interleukin-7, NT-I7, Increases Cytotoxic CD8 T Cells and Enhances Survival in Mouse Glioma Models. ( Campian, JL; Chheda, MG; Ferrando-Martinez, S; Ghosh, S; Hallahan, D; Hu, T; Jash, A; Kapoor, V; Lee, BH; Mahadevan, A; Page, L; Rifai, K; Thotala, D; Thotala, S; Wolfarth, AA; Yan, R; Yang, SH, 2022)
"Nearly 10% of patients with adult diffuse glioma develop clinically significant myelotoxicity while on temozolomide (TMZ) leading to treatment interruptions."4.12Temozolomide-induced myelotoxicity and single nucleotide polymorphisms in the MGMT gene in patients with adult diffuse glioma: a single-institutional pharmacogenetic study. ( Chatterjee, A; Dasgupta, A; Epari, S; Gupta, T; Kota, PK; Kowtal, P; Moitra, P; Patil, V; Sarin, R, 2022)
"We report a case of oligodendroglioma that had consistent histopathological features as well as a distinct change in 1p/19q status in the second recurrence, after temozolomide chemotherapy and radiotherapy."4.12Recurrent oligodendroglioma with changed 1p/19q status. ( Barresi, V; Calicchia, M; Ghimenton, C; Mafficini, A; Musumeci, A; Piredda, ML; Scarpa, A, 2022)
" The present study was designed to investigate the role of hsa_circ_0072309 in autophagy and temozolomide (TMZ) sensitivity in glioblastoma (GBM)."4.12Hsa_circ_0072309 enhances autophagy and TMZ sensitivity in glioblastoma. ( Chen, Q; Deng, G; Liu, B; Sun, Q; Xu, Y; Xu, Z; Ye, L; Yuan, F; Zhang, S, 2022)
"It is necessary to elucidate the individual effects of temozolomide (TMZ) on carcinogenesis and tumor resistance to chemotherapy mechanisms."4.12The Different Temozolomide Effects on Tumorigenesis Mechanisms of Pediatric Glioblastoma PBT24 and SF8628 Cell Tumor in CAM Model and on Cells In Vitro. ( Alonso, MM; Balnytė, I; Damanskienė, E; Preikšaitis, A; Stakišaitis, D; Valančiūtė, A, 2022)
"A broad panel of primary and temozolomide (TMZ)-resistant human glioma cell lines were screened by cell viability assays, flow cytometry, and crystal violet assays to investigate the therapeutic efficacy of Gamitrinib."4.12Antitumor Activity of a Mitochondrial-Targeted HSP90 Inhibitor in Gliomas. ( Abdullah, K; Ashley, DM; Bowie, M; Chen, Y; Deek, RA; Du, K; Flaherty, KT; Hariharan, S; Herlyn, M; Keir, ST; Khasraw, M; Ku, Y; Labrie, M; Li, S; Lin, X; Liu, H; Liu, L; Lu, Y; Mills, GB; Savani, MR; Sugarman, ET; Tian, M; Waitkus, M; Wei, S; Wei, Z; Wu, D; Wu, K; Yin, D; Yu, S; Zhang, G, 2022)
"Temozolomide (TMZ) is a standard-of-care chemotherapeutic drug for the treatment of glioblastoma (GBM), but TMZ-acquired resistance limits its therapeutic effect."4.12Efficacy of Temozolomide-Conjugated Gold Nanoparticle Photothermal Therapy of Drug-Resistant Glioblastoma and Its Mechanism Study. ( Chu, L; Liu, X; Sha, C; Sun, K; Sun, Y; Wang, A; Wang, S; Xu, L; Yang, X; Yu, Y; Zhou, L, 2022)
"Temozolomide (TMZ) monotherapy is known to be insufficient for resistant/relapsed glioblastoma (GBM), thus seeking a sensitization agent for TMZ is necessary."4.12Regorafenib Reverses Temozolomide-Induced CXCL12/CXCR4 Signaling and Triggers Apoptosis Mechanism in Glioblastoma. ( Ali, AAA; Chiang, IT; Chou, SY; Hsu, FT; Hsu, TI; Liu, HS; Liu, YC, 2022)
"This retrospective study enrolled 65 patients with IDH wild-type recurrent glioblastoma who received standard therapy and then received either bevacizumab (46 patients) or temozolomide (19 patients) as a secondary treatment."4.12Contrast enhancing pattern on pre-treatment MRI predicts response to anti-angiogenic treatment in recurrent glioblastoma: comparison of bevacizumab and temozolomide treatment. ( Kim, HS; Kim, JH; Kim, YH; Moon, HH; Park, JE, 2022)
"Temozolomide (TMZ) is a first-line chemotherapeutic agent for the treatment of glioma."4.12The RNA-binding protein fragile-X mental retardation autosomal 1 (FXR1) modulates glioma cells sensitivity to temozolomide by regulating ferroptosis. ( Duan, S; Gong, F; Li, Q; Wei, Y, 2022)
"Myelosuppression is the major toxicity encountered during temozolomide chemoradiotherapy for newly diagnosed glioblastoma."4.12Prognostic significance of therapy-induced myelosuppression in newly diagnosed glioblastoma. ( Chinot, O; Gorlia, T; Le Rhun, E; Nabors, B; Oppong, FB; Preusser, M; Stupp, R; Vanlancker, M; Weller, M; Wick, W, 2022)
"We retrospectively analyzed cytopenia during temozolomide-based concomitant radiochemotherapy in 492 patients with glioma."4.12Sex-Dependent Analysis of Temozolomide-Induced Myelosuppression and Effects on Survival in a Large Real-life Cohort of Patients With Glioma. ( Filipski, K; Filmann, N; Fokas, E; Forster, MT; Harter, PN; Herrlinger, U; Ronellenfitsch, MW; Steinbach, JP; Voss, M; Zeiner, PS, 2022)
" Temozolomide is widely used first-line chemotherapy drug to treat glioma patients, but development of temozolomide resistance is almost inevitable."4.12Inhibitory effects of temozolomide on glioma cells is sensitized by RSL3-induced ferroptosis but negatively correlated with expression of ferritin heavy chain 1 and ferritin light chain. ( Bian, XW; Cai, XW; Cao, MF; Gai, QJ; He, J; He, MM; Leng, P; Lu, HM; Mao, M; Qin, Y; Wang, C; Wang, Y; Wang, YX; Wen, XM; Yang, FC; Yao, XH; Yao, XX; Zhu, J, 2022)
" We herein investigate the therapeutic potential of bioinformatically identified HOTAIR transferred by serum-derived EVs (serum-EVs) in temozolomide (TMZ) resistance of glioblastoma (GBM) and the downstream mechanisms."4.12Serum-derived extracellular vesicles facilitate temozolomide resistance in glioblastoma through a HOTAIR-dependent mechanism. ( Han, J; Wang, S; Wang, X; Wang, Y; Wei, K; Xu, H; Yu, X, 2022)
"The aim of this study was to clarify whether PET with 11C-methyl-l-methionine (11C-met PET) can predict consequential outcomes at the time of discontinuing temozolomide (TMZ)-adjuvant chemotherapy in patients with residual isocitrate dehydrogenase gene (IDH)-mutant lower-grade glioma."4.12PET With 11C-Methyl-l-Methionine as a Predictor of Consequential Outcomes at the Time of Discontinuing Temozolomide-Adjuvant Chemotherapy in Patients With Residual IDH-Mutant Lower-Grade Glioma. ( Beppu, T; Fujiwara, S; Iwaya, T; Nomura, JI; Ogasawara, K; Sasaki, T; Sato, Y; Sugai, T; Terasaki, K; Yamada, N, 2022)
"Gliosarcoma is an uncommon glioblastoma subtype, for which MGMT promoter methylation's relationship with response to temozolomide chemotherapy is unclear."4.12Survival outcomes associated with MGMT promoter methylation and temozolomide in gliosarcoma patients. ( Iorgulescu, JB; Kavouridis, VK; Ligon, KL; Wen, PY, 2022)
"We sought to evaluate the effects of concurrent temozolomide-based chemoradiation therapy on neurocognitive function in patients with low-grade glioma (LGG)."4.12Cognitive function after concurrent temozolomide-based chemoradiation therapy in low-grade gliomas. ( Ahluwalia, MS; Angelov, L; Barnett, GH; Chao, ST; Chen, Y; Hogan, T; Kissel, C; Lapin, B; Mohammadi, A; Murphy, ES; Naugle, R; Park, DY; Parsons, MW; Peereboom, DM; Schuermeyer, I; Stevens, GHJ; Suh, JH; Tewari, S; Tom, MC; Yu, JS, 2022)
"Temozolomide (TMZ) is generally applied for glioma treatment, while drug resistance of TMZ limits its therapeutic efficacy."4.12Mannose inhibits proliferation and promotes apoptosis to enhance sensitivity of glioma cells to temozolomide through Wnt/β-catenin signaling pathway. ( Fei, YQ; Shi, RT; Song, Z; Wu, JZ; Zhou, YF, 2022)
"The standard treatment for glioblastoma is maximal surgical resection followed by postoperative temozolomide administration combined with radiation therapy."4.12[Glioblastoma That Does Not Improve with Standard Treatment: Standard and Personalized Treatment Making The Most of Limited Modalities]. ( Imai, R; Sasaki, H, 2022)
"To study the relationship between temozolomide (TMZ) chemotherapy-resistant cells and stem cells in gliomas."4.12Preliminary Study on Relationship Between Temozolomide Chemotherapy-Resistant Cells and Stem Cells in Gliomas. ( Cunzu, W; Dingchao, X; Min, X; Xun, Z, 2022)
" However, the role of lncRNAs in temozolomide (TMZ) resistance in glioblastoma multiforme (GBM) remains largely undefined."4.12lncRNA XLOC013218 promotes cell proliferation and TMZ resistance by targeting the PIK3R2-mediated PI3K/AKT pathway in glioma. ( Guo, H; He, Z; Lenahan, C; Liu, B; Tang, W; Wang, C; Xu, N; Zeng, H; Zhou, J, 2022)
"To investigate the function of primary cilia in regulating the cellular response to temozolomide (TMZ) and ionizing radiation (IR) in glioblastoma (GBM)."4.12Inhibition of Ciliogenesis Enhances the Cellular Sensitivity to Temozolomide and Ionizing Radiation in Human Glioblastoma Cells. ( Cai, H; Gao, L; He, JP; Ma, W; Peng, SP; Tian, HB; Wang, JF; Wei, L, 2022)
"Glioblastoma multiforme (GBM) is an aggressive brain tumor, often occurring with seizures managed with antiepileptic drugs, such as levetiracetam (LEV)."4.12Association of plasma levetiracetam concentration, MGMT methylation and sex with survival of chemoradiotherapy-treated glioblastoma patients. ( Banchi, M; Bocci, G; Cucchiara, F; Danesi, R; Di Paolo, A; Giannini, N; Giorgi, FS; Luci, G; Orlandi, P; Pasqualetti, F, 2022)
"Temozolomide (TMZ) is the primary chemotherapeutic drug for treating glioblastoma (GBM); however, the final clinical outcome is considerably limited by the poor response and resistance to TMZ."4.12SOCS5 contributes to temozolomide resistance in glioblastoma by regulating Bcl-2-mediated autophagy. ( Han, L; Hu, L; Yang, F; Yu, J; Zhao, M; Zhou, H, 2022)
"Temozolomide (TMZ) is a chemotherapeutic agent that has been the first-line standard of care for the aggressive brain cancer glioblastoma (GBM) since 2005."4.12Temozolomide-induced guanine mutations create exploitable vulnerabilities of guanine-rich DNA and RNA regions in drug-resistant gliomas. ( Alamillo-Ferrer, C; Cheng, SY; Drewry, DH; Erdogdu, B; Goenka, A; Goldlust, SA; Haddad, BR; Hogg, JR; Hu, B; Jin, L; Pertea, M; Pickett, JE; Razaghi, R; Riggins, RB; Sadowski, N; Song, X; Tiek, DM; Timp, W; Wells, CI; Zuercher, WJ, 2022)
"Temozolomide (TMZ) is the first-line drug for the clinical treatment of glioblastoma (GBM), but drug resistance limits its treatment benefits."4.12Propofol enhances the sensitivity of glioblastoma cells to temozolomide by inhibiting macrophage activation in tumor microenvironment to down-regulate HIF-1α expression. ( Yun, K; Zhao, W, 2022)
"The mechanism by which glioblastoma evades temozolomide (TMZ)-induced cytotoxicity is largely unknown."4.12SH3GLB1-related autophagy mediates mitochondrial metabolism to acquire resistance against temozolomide in glioblastoma. ( Chang, KY; Chen, PY; Chen, SH; Cheng, SM; Chi, PI; Chien, CH; Chu, JM; Chuang, JY; Huang, CY; Hwang, DY; Lai, CC; Lee, JS; Liao, WA; Liu, CC; Wu, AC; Yang, ST; Yang, WB, 2022)
"Resistance to temozolomide (TMZ) is a major obstacle to preventing glioblastoma (GBM) recurrence after surgery."4.12PDIA3P1 promotes Temozolomide resistance in glioblastoma by inhibiting C/EBPβ degradation to facilitate proneural-to-mesenchymal transition. ( Deng, L; Fan, Y; Gao, Z; Guo, X; Li, G; Qi, Y; Sun, C; Wang, S; Xu, J; Xue, H; Zhang, P; Zhao, R; Zhao, S, 2022)
"Temozolomide (TMZ) resistance remains the main therapy challenge in patients with glioblastoma multiforme (GBM)."4.12TTK Protein Kinase promotes temozolomide resistance through inducing autophagy in glioblastoma. ( Gao, G; Wang, Y; Wei, X; Yu, J, 2022)
"We included 41 patients with isocitrate dehydrogenase 1/2-wildtype glioblastoma, who received 12 or more cycles of temozolomide therapy between June 2006 and December 2019."4.12Continuing maintenance temozolomide therapy beyond 12 cycles confers no clinical benefit over discontinuation at 12 cycles in patients with IDH1/2-wildtype glioblastoma. ( Miyakita, Y; Narita, Y; Ohno, M; Takahashi, M; Tamura, Y; Yanagisawa, S, 2022)
" Optical microscopy and flow cytometry were employed to assess the differences in glioblastoma cells morphology, proliferation, and cytotoxicity of anticancer drug temozolomide (TMZ) due to increased substrate viscosity."4.12Substrate viscosity impairs temozolomide-mediated inhibition of glioblastoma cells' growth. ( Bucki, R; Cieśluk, M; Kochanowicz, J; Kułakowska, A; Piktel, E; Pogoda, K; Skłodowski, K; Wnorowska, U, 2022)
" Temozolomide is the standard of care for gliomas, frequently results in resistance to drug and tumor recurrence."4.12Anticancer Effect of Cathelicidin LL-37, Protegrin PG-1, Nerve Growth Factor NGF, and Temozolomide: Impact on the Mitochondrial Metabolism, Clonogenic Potential, and Migration of Human U251 Glioma Cells. ( Alaverdian, DA; Buntovskaya, AS; Chernov, AN; Fedorov, EV; Filatenkova, TA; Galimova, ES; Glushakov, RI; Kim, AV; Matsko, MV; Shamova, OV; Skliar, SS; Tsapieva, AN, 2022)
"Our previous researches showed that essential oil (EO) of chuanxiong could promote temozolomide (TMZ) entry into glioma cells in vitro and enhance TMZ-induced anticancer efficiency in vivo, and therefore, the aim of this study was to investigate whether EO could increase the concentration accumulation of TMZ in brain or tumor of C6 glioma rats and the related mechanisms."4.12Essential oil of Ligusticum chuanxiong Hort. Regulated P-gp protein and tight junction protein to change pharmacokinetic parameters of temozolomide in blood, brain and tumor. ( Hu, PY; Liu, SS; Liu, XJ; Shuai, SY; Yang, M; Yue, PF; Zhang, GS; Zheng, Q, 2022)
"The DNA alkylating agent temozolomide (TMZ), is the first-line therapeutic for the treatment of glioblastoma (GBM)."4.12Potentiation of temozolomide activity against glioblastoma cells by aromatase inhibitor letrozole. ( DasGupta, B; Dave, N; Desai, JM; Desai, PB; Gudelsky, GA; Karve, AS; Phoenix, TN; Plas, DR; Sengupta, S; Wise-Draper, TM, 2022)
"The complex of formononetin and calycosin (FMN/CAL) shows a synergistic effect on temozolomide in the treatment of malignant glioma, however the mechanism is unclear."4.12The mechanism of formononetin/calycosin compound optimizing the effects of temozolomide on C6 malignant glioma based on metabolomics and network pharmacology. ( Fan, H; Fan, Y; Huang, T; Li, J; Li, S; Qiu, R; Zhang, Q; Zhou, Y, 2022)
"A MEX3A/CCR4-NOT/MSH2 axis plays a crucial role in promoting temozolomide resistance, providing new insights into the function of MEX3A and suggesting MEX3A as a potential therapeutic target in therapy-resistant glioblastoma."4.12MEX3A Impairs DNA Mismatch Repair Signaling and Mediates Acquired Temozolomide Resistance in Glioblastoma. ( Gan, T; Miao, F; Nie, E; Qian, X; Shen, Z; Shi, Q; Wang, P; Wang, Q; Wang, Y; Xie, M; Zhao, S, 2022)
"The role of temozolomide chemotherapy alone in isocitrate dehydrogenase (IDH)-mutant astrocytomas has not been conclusively determined."4.12Limited efficacy of temozolomide alone for astrocytoma, IDH-mutant, CNS WHO grades 2 or 3. ( Becker, H; Blobner, J; Egensperger, R; Katzendobler, S; Niyazi, M; Quach, S; Suchorska, B; Thiele, F; Thon, N; Tonn, JC; Weller, J; Weller, M, 2022)
"Systemic chemotherapy including monotherapy with temozolomide (TMZ) or bevacizumab (BEV); two-drug combinations, such as irinotecan (IRI) and BEV, TMZ and BEV and a three-drug combination with TMZ, IRI and BEV (TIB) have been used in treating patients with progressive high-grade gliomas including glioblastoma (GBM)."4.12Postmortem study of organ-specific toxicity in glioblastoma patients treated with a combination of temozolomide, irinotecan and bevacizumab. ( Ballester, LY; Bhattacharjee, MB; Brown, RE; Buja, LM; Chen, L; Glass, WF; Hergenroeder, GW; Hunter, RL; Linendoll, N; Lu, G; Pilichowska, M; Pillai, AK; Rao, M; Tian, X; Wu, JK; Zhang, R; Zhu, JJ; Zhu, P, 2022)
"Temozolomide (TMZ) resistance limits its use in glioblastoma (GBM)."4.12Hsa_circ_0043949 reinforces temozolomide resistance via upregulating oncogene ITGA1 axis in glioblastoma. ( Leng, H; Li, X; Wang, N; Xu, L; Yuan, H, 2022)
"Brain radiotherapy combined with concomitant and six cycles of adjuvant temozolomide (TMZ) is the standard treatment for newly diagnosed high-grade gliomas (HGGs)."4.12Standard or extended STUPP? Optimal duration of temozolomide for patients with high-grade gliomas: a retrospective analysis. ( Ai, P; Chen, J; He, L; Huang, Y; Li, R; Liu, Z; Pei, Y; Peng, X; Wang, J; Wei, Z; Zhao, F, 2022)
"Although temozolomide is the primary chemotherapeutic agent in glioblastoma, current studies have focused on its combinational applications to overcome resistance by targeting multiple pathways."4.12Ruxolitinib enhances cytotoxic and apoptotic effects of temozolomide on glioblastoma cells by regulating WNT signaling pathway-related genes. ( Biray Avci, C; Goker Bagca, B; Ozates, NP, 2022)
"It has been noted that temozolomide resistance occurs in a number of malignancies, including glioma, although the underlying cause of this is unknown."4.12CD147 Protein Expression and Temozolomide Resistance in Glioma Cells: An Ex vivo and In vivo Study. ( Bai, S; Chen, H; Fan, LL; Hu, Y; Luo, GQ; Yan, ZJ, 2022)
" The main cause is the presence of glioma stem cells (GSCs), exceptionally resistant to temozolomide (TMZ) treatment."4.12TRPML2 Mucolipin Channels Drive the Response of Glioma Stem Cells to Temozolomide and Affect the Overall Survival in Glioblastoma Patients. ( Amantini, C; Maggi, F; Morelli, MB; Nabissi, M; Pallini, R; Ricci-Vitiani, L; Santoni, G, 2022)
"It was found that radiotherapy combined with temozolomide administration often increased the size of the original lesion or produced a new glioblastoma lesion."4.12Apatinib combined with temozolomide treatment for pseudoprogression in glioblastoma: A case report. ( Cheng, P; Han, Q; Ma, H; Yang, H; Zhao, M; Zhao, Y, 2022)
"Thirty rats with glioma were divided into control group, temozolomide (TMZ) group (TMZ 30 mg/kg once daily for 5 day), and TMZ plus Caffeine group (TMZ 30 mg/kg once daily for 5 day and caffeine 100 mg/kg once daily for 2 weeks)."4.12Caffeine Inhibits Growth of Temozolomide-Treated Glioma via Increasing Autophagy and Apoptosis but Not via Modulating Hypoxia, Angiogenesis, or Endoplasmic Reticulum Stress in Rats. ( Chen, JC; Hwang, JH, 2022)
" Therefore, we aimed to examine the Synergistic effects of Gefitinib (GFI) in combination with Temozolomide on VEGF and MMPs in glioma cell line (U87MG)."4.12Synergistic Effect of Gefitinib and Temozolomide on U87MG Glioblastoma Angiogenesis. ( Hossienpour, M; Karami, A; Kiani, A; Mohammadi Noori, E; Najafi, K; Rahpyma, M, 2022)
"Glioma is the most frequent primary malignancy in the brain; temozolomide (TMZ) is the first-line chemotherapeutic agent used to combat this tumor."4.02AEG-1 silencing attenuates M2-polarization of glioma-associated microglia/macrophages and sensitizes glioma cells to temozolomide. ( Li, J; Ma, Y; Sun, X; Sun, Y; Wang, Y; Zhang, X; Zhao, X, 2021)
"Glioblastomas (GBM) often acquire resistance against temozolomide (TMZ) after continuous treatment and recur as TMZ-resistant GBM (TMZ-R-GBM)."4.02Lomustine and nimustine exert efficient antitumor effects against glioblastoma models with acquired temozolomide resistance. ( Fujii, T; Ichimura, K; Kawauchi, D; Kobayashi, T; Kondo, A; Nakano, T; Narita, Y; Sasaki, N; Satomi, K; Takahashi, M; Tomiyama, A; Uchida, E; Wada, K; Yamamuro, S; Yoshino, A, 2021)
"Despite the development of new treatment protocols for glioblastoma (GBM), temozolomide (TMZ) resistance remains a primary hindrance."4.02Interplay of m ( Chen, S; Gao, Z; Li, F; Li, Y; Liu, Q; Long, T; Long, W; Pan, Y; Qin, C; Sun, Z; Yi, Y; Yu, J; Zhang, C; Zhao, W, 2021)
" To validate this approach, we determined ex vivo response to temozolomide in a retrospective cohort of 69 glioblastoma patient-derived neurosphere models with matched patient survival and genomics."4.02Functional drug susceptibility testing using single-cell mass predicts treatment outcome in patient-derived cancer neurosphere models. ( Chow, KH; Geduldig, J; Kim, AS; Ligon, KL; Malinowski, S; Manalis, SR; Mirza, M; Stockslager, MA; Touat, M; Wen, PY; Yoon, JC, 2021)
" Here, we show that NSUN6 methylates both large and small RNA in glioblastoma and controls glioblastoma response to temozolomide with or without influence of the MGMT promoter status, with high NSUN6 expression conferring survival benefit to glioblastoma patients and in other cancers."4.02NSUN6, an RNA methyltransferase of 5-mC controls glioblastoma response to temozolomide (TMZ) via NELFB and RPS6KB2 interaction. ( Awah, CU; Mazdoom, CM; Ogunwobi, OO; Winter, J, 2021)
" CDC20 expression is increased in a variety of tumors and associated with temozolomide (TMZ) resistance in glioma cells."4.02Apcin inhibits the growth and invasion of glioblastoma cells and improves glioma sensitivity to temozolomide. ( Ding, Y; He, L; Pan, Y; Song, X; Yu, S; Zhang, C; Zheng, C, 2021)
"About 95% of Glioblastoma (GBM) patients experience tumor relapse as a consequence of resistance to the first-line standard chemotherapy using temozolomide (TMZ)."4.02Inhibition of Carbonic Anhydrase 2 Overcomes Temozolomide Resistance in Glioblastoma Cells. ( Bartsch, JW; Culmsee, C; Elsässer, K; Nimsky, C; Pagenstecher, A; Schäfer, A; Zhang, Z; Zhao, K; Zhong, L, 2021)
"To explore whether or not aberrant expression of miR-29b in glioblastoma multiforme (GBM) cells was associated with temozolomide (TMZ) resistance and to elucidate potential underlying mechanisms."4.02Micro-RNA29b enhances the sensitivity of glioblastoma multiforme cells to temozolomide by promoting autophagy. ( Luan, XP; Xu, JX; Yang, Y; Zhang, X, 2021)
"Temozolomide (TMZ) is widely used for glioma therapy in the clinic."4.02LncRNA MIR155HG Promotes Temozolomide Resistance by Activating the Wnt/β-Catenin Pathway Via Binding to PTBP1 in Glioma. ( He, X; Liu, Q; Sheng, J; Wang, K; Yu, W; Zhu, S, 2021)
"The study includes 132 IDH-wildtype glioblastoma patients treated between 2013 and 2017 with open resection followed by radiotherapy with concomitant and maintenance temozolomide."4.02Age-stratified clinical performance and survival of patients with IDH-wildtype glioblastoma homogeneously treated by radiotherapy with concomitant and maintenance temozolomide. ( Berger, K; Budach, W; Felsberg, J; Hänggi, D; Haussmann, J; Kamp, MA; Knipps, J; Malzkorn, B; Mijderwijk, HJ; Rapp, M; Reifenberger, G; Sabel, M; Steiger, HJ; Turowski, B, 2021)
"We report a case of acute interstitial nephritis with associated nephrogenic diabetes insipidus in a patient treated with temozolomide and sulfamethoxazole-trimethoprim for glioblastoma multiforme."4.02Acute interstitial nephritis and nephrogenic diabetes insipidus following treatment with sulfamethoxazole-trimethoprim and temozolomide. ( Athavale, A; Gallagher, M; Jardine, M; Morris, J; Ritchie, A; Sen, S; Wang, AY, 2021)
" Temozolomide is an oral DNA-alkylating agent capable of crossing the blood-brain barrier and used as chemotherapy primarily to treat glioblastoma and other brain cancers."4.02Central diabetes insipidus induced by temozolomide: A report of two cases. ( Capes, A; Duck, L; Duprez, T; Labriola, L; Mahiat, C; Whenham, N, 2021)
"Temozolomide (TMZ) is the major chemotherapy agent in glioma, and isocitrate dehydrogenase (IDH) is a well-known prognostic marker in glioma."4.02Identification of a three-long non-coding RNA signature for predicting survival of temozolomide-treated isocitrate dehydrogenase mutant low-grade gliomas. ( Chen, W; Jing, J; Li, R; Mao, P; Sun, Q; Wang, J; Wang, M; Yu, X, 2021)
"The purpose of this study is to clarify the clinical features of temozolomide (TMZ)-related hepatitis B virus (HBV) reactivation and to identify HBV reactivation predictive factors."4.02Hepatitis B virus reactivation during temozolomide administration for malignant glioma. ( Chonan, M; Inoue, J; Kanamori, M; Masamune, A; Osada, Y; Saito, R; Shimoda, Y; Shoji, T; Tominaga, T; Uenohara, H, 2021)
"8% of actual body weight calculated body surface area dosing was determined for concurrent phase temozolomide."4.02Actual body weight dosing of temozolomide and overall survival in patients with glioblastoma. ( Chambers, C; Coppens, R; de Robles, P; Dersch-Mills, D; Folkman, F; Ghosh, S; Hsu, PYH; Leckie, C, 2021)
"EORTC study 22033-26033 showed no difference in progression-free survival between high-risk low-grade glioma receiving either radiotherapy (RT) or temozolomide (TMZ) chemotherapy alone as primary treatment."4.02Memory in low-grade glioma patients treated with radiotherapy or temozolomide: a correlative analysis of EORTC study 22033-26033. ( Baumert, BG; Ben Hassel, M; Bromberg, JC; Drijver, AJ; Eekers, DBP; Freixa, SV; Golfinopoulos, V; Gorlia, T; Hoang-Xuan, K; Hottinger, AF; Klein, M; Lucas, A; Reijneveld, JC; Stupp, R; Taphoorn, MJB; Tzuk-Shina, T; van den Bent, MJ; Vauleon, E, 2021)
"Using data from the German multi-center E-HIT-REZ-2005 study, we examined the role of local therapy and the efficacy of chemotherapy with blockwise temozolomide (TMZ) in children and adolescents with recurrent ependymomas."4.02Local and systemic therapy of recurrent ependymoma in children and adolescents: short- and long-term results of the E-HIT-REZ 2005 study. ( Adolph, JE; Bison, B; Bode, U; Faldum, A; Fleischhack, G; Frühwald, MC; Kortmann, RD; Krauß, J; Kwiecien, R; Mikasch, R; Mynarek, M; Obrecht, D; Pajtler, KW; Pfister, SM; Pietsch, T; Rutkowski, S; Schüller, U; Timmermann, B; Tippelt, S; von Hoff, K; Warmuth-Metz, M; Witt, H; Witt, O; Zeller, J, 2021)
"Limited therapeutic efficacy of temozolomide (TMZ) against glioblastomas highlights the importance of exploring new drugs for clinical therapy."4.02Guanabenz Sensitizes Glioblastoma Cells to Sunitinib by Inhibiting GADD34-Mediated Autophagic Signaling. ( Chen, KC; Chen, PH; Cheng, CH; Ho, KH; Lee, YT; Shih, CM, 2021)
"Temozolomide (TMZ) is a first-line chemotherapy drug for the treatment of malignant glioma and resistance to it poses a major challenge."4.02Regulation of temozolomide resistance in glioma cells via the RIP2/NF-κB/MGMT pathway. ( Hu, YH; Jiao, BH; Wang, CY; Wu, JL, 2021)
" Temozolomide (TMZ) is widely used in the treatment of glioblastoma and is considered as the primary treatment modality."4.02Molecular biological investigation of temozolomide and KC7F2 combination in U87MG glioma cell line. ( Abbaszade, Z; Avci, CB; Bagca, BG, 2021)
" The chemotherapy drug temozolomide (TMZ), embedded in nanobubbles (NBs) and combined with persistent luminescent nanoparticles (PLNs), has been used to treat glioblastoma (GBM) effectively through image tracking."4.02Long-Term Near-Infrared Signal Tracking of the Therapeutic Changes of Glioblastoma Cells in Brain Tissue with Ultrasound-Guided Persistent Luminescent Nanocomposites. ( Chan, MH; Cheng, CL; Feng, SJ; Hsiao, M; Liu, RS, 2021)
" Treatment of patients suffering from relapsed/refractory glioblastoma (GBM) with a combination of depatux-m and temozolomide (TMZ) tended to increase overall survival."4.02Synergistic therapeutic benefit by combining the antibody drug conjugate, depatux-m with temozolomide in pre-clinical models of glioblastoma with overexpression of EGFR. ( Alvey, C; Anderson, M; Ansell, P; Boghaert, ER; Falls, HD; Mishra, S; Mitten, MJ; Oleksijew, A; Palma, J; Phillips, AC; Reilly, EB; Vaidya, KS; Zelaya-Lazo, AL, 2021)
"IDH-mutant anaplastic astrocytomas (AAs) are chemosensitive tumors for which the best choice of adjuvant chemotherapy between procarbazine, lomustine, and vincristine (PCV) or temozolomide (TMZ) after radiotherapy (RT) remains unclear."4.02Radiotherapy Plus Procarbazine, Lomustine, and Vincristine Versus Radiotherapy Plus Temozolomide for IDH-Mutant Anaplastic Astrocytoma: A Retrospective Multicenter Analysis of the French POLA Cohort. ( Bronniman, C; Carpentier, C; Ciron, DL; Dehais, C; Ducray, F; Esteyrie, V; Figarella-Branger, D; Martin, E; Moyal, EC; Network, P; Pouessel, D; Uro-Coste, E, 2021)
"Temozolomide (TMZ), an alkylating agent with a broad-spectrum antitumor activity, ability to cross blood-brain barrier (BBB), shown to be effective against malignant glioma."4.02Pharmacogenetics of ATP binding cassette transporter MDR1(1236C>T) gene polymorphism with glioma patients receiving Temozolomide-based chemoradiation therapy in Indian population. ( Baburaj, G; Jose, A; Kumar, JP; Munisamy, M; Munisamy, S; Subbiah, V; Thomas, L, 2021)
"Previous studies showed that the chemotherapeutic effect of temozolomide (TMZ) and vincristine (VCR) against glioma might be blunted by the co-culture with astrocytes, and connexin-43 (CX43) was thought to play a vital role in the communication between glioma cells and astrocytes."4.02AS602801 sensitizes glioma cells to temozolomide and vincristine by blocking gap junction communication between glioma cells and astrocytes. ( Fan, T; Fu, X; Gong, Y; Huang, Y; Li, Z; Wang, H; Xiang, P; Zhang, S, 2021)
" However, whether glioma stem cells (GSCs) can be sensitized to chemotherapy via combined treatment with temozolomide (TMZ) and nicardipine is unclear."4.02Nicardipine sensitizes temozolomide by inhibiting autophagy and promoting cell apoptosis in glioma stem cells. ( Dong, J; Dong, X; Jiang, Q; Li, H; Liu, L; Shi, J; Wang, H; Wang, L, 2021)
"To assess the recurrence interval and predictive significance of TP53 expression and O6-methylguanine-DNA methyltransferase (MGMT) promoter methylation in glioblastomas treated with radiotherapy and combined chemotherapies, including temozolomide, lomustine, procarbazine and bevacizumab."4.02Prognostic value of TP53 expression and MGMT methylation in glioblastoma patients treated with temozolomide combined with other chemotherapies. ( Alghamdi, B; Alkhayyat, S; Baeesa, S; Bardeesi, A; Bari, MO; Butt, NS; Dallol, A; Kurdi, M; Lary, AI; Maghrabi, Y; Mohamed, F; Saeedi, R; Samkari, A, 2021)
"Temozolomide (TMZ) is the internationally recognized and preferred drug for glioma chemotherapy treatment."4.02Hsa_circ_0110757 upregulates ITGA1 to facilitate temozolomide resistance in glioma by suppressing hsa-miR-1298-5p. ( Chen, Z; Li, H; Li, Y; Liu, Q; Su, J; Wu, M; Zhang, C, 2021)
"In this retrospective analysis, only adult patients with supratentorial IDHwt glioblastoma were included who were treated with temozolomide-based chemoradiotherapy after surgery."4.02Survival impact of incidental subventricular zone irradiation in IDH-wildtype glioblastoma. ( Boterberg, T; Hallaert, G; Kalala, JP; Pinson, H; Sweldens, C; Van den Broecke, C; Van Roost, D, 2021)
"The alkylating agent, temozolomide (TMZ), is the most commonly used chemotherapeutic for the treatment of glioblastoma (GBM)."4.02CDK1 is up-regulated by temozolomide in an NF-κB dependent manner in glioblastoma. ( Arina, A; Bernal, GM; Cahill, KE; Campbell, PS; Crawley, CD; Mansour, N; Voce, DJ; Weichselbaum, RR; Wu, L; Yamini, B, 2021)
"Glioblastoma is the most common malignant brain tumor, currently treated by surgery followed by concomitant radiotherapy and temozolomide-based chemotherapy."4.02Adjuvant therapeutic potential of moderate hypothermia for glioblastoma. ( Chabardès, S; Fulbert, C; Ratel, D, 2021)
" The present study evaluates the effects of AT101, alone or in combination with temozolomide (TMZ), in a microenvironmental glioma stem cell niche model of two GBM cell lines (U251MG and U87MG)."4.02Effects of the Anti-Tumorigenic Agent AT101 on Human Glioblastoma Cells in the Microenvironmental Glioma Stem Cell Niche. ( Caylioglu, D; Held-Feindt, J; Hellmold, D; Kubelt, C; Meyer, RJ; Synowitz, M, 2021)
" Previous results with the preclinical GL261 glioblastoma (GB) showed that combination treatment of temozolomide (TMZ) + CX-4945 (protein kinase CK2 inhibitor) outperformed single treatments, provided an immune-friendly schedule was followed."4.02Successful Partnerships: Exploring the Potential of Immunogenic Signals Triggered by TMZ, CX-4945, and Combined Treatment in GL261 Glioblastoma Cells. ( Arús, C; Candiota, AP; Martínez-Escardó, L; Villamañan, L; Yuste, VJ, 2021)
"Chemotherapy improves overall survival after surgery and radiotherapy for newly diagnosed high-risk IDH-mutant low-grade gliomas (LGGs), but a proportion of patients treated with temozolomide (TMZ) will develop recurrent tumors with TMZ-induced hypermutation."4.02Temozolomide-induced hypermutation is associated with distant recurrence and reduced survival after high-grade transformation of low-grade IDH-mutant gliomas. ( Berger, MS; Butowski, N; Chang, SM; Choi, S; Clarke, JL; Costello, JF; Grimmer, MR; Haas-Kogan, D; Hilz, S; Hong, C; Mazor, T; McDermott, M; Molinaro, AM; Oberheim Bush, NA; Phillips, JJ; Shai, A; Solomon, DA; Taylor, JW; Villanueva-Meyer, J; Wahl, M; Wainer, BH; Yu, Y, 2021)
" However, the alterations in gut microbiota observed during glioma growth and temozolomide (TMZ) therapy remain poorly understood."4.02Temozolomide-Induced Changes in Gut Microbial Composition in a Mouse Model of Brain Glioma. ( Jiang, Y; Jin, XQ; Li, J; Li, XC; Li, YR; Li, ZQ; Ma, C; Wang, ZF; Wu, BS; Yao, J, 2021)
"Patients (n = 142) with molecularly defined oligodendroglioma (WHO 2016) were assigned to four cohorts: W&S, wait-and-scan after stereotactic biopsy (n = 59); RES, surgical resection only (n = 27); TMZ, temozolomide after biopsy (n = 26) or PCV (n = 30) after biopsy."4.02PCV chemotherapy alone for WHO grade 2 oligodendroglioma: prolonged disease control with low risk of malignant progression. ( Egensperger, R; Karschnia, P; Katzendobler, S; Lietke, S; Suchorska, B; Thon, N; Tonn, JC; Weller, J; Weller, M, 2021)
"Our data revealed (i) a clinical association of the EMT-like process with glioma malignancy and a poor survival and (ii) an anticancer and temozolomide sensitizing effect of rabeprazole by repressing EMT."4.02Rabeprazole has efficacy per se and reduces resistance to temozolomide in glioma via EMT inhibition. ( Babu, D; Mudiraj, A; Panigrahi, M; Prakash Babu, P; Y B V K, C; Yadav, N, 2021)
"Temozolomide (TMZ) resistance limits its application in glioma."4.02Warburg effect-promoted exosomal circ_0072083 releasing up-regulates NANGO expression through multiple pathways and enhances temozolomide resistance in glioma. ( Bu, X; Chen, X; Ding, C; Gu, J; Kang, D; Lin, Y; Lin, Z; Sun, Y; Wu, X; Wu, Z; Yi, X; You, H; Zhang, G, 2021)
" This study investigated whether the improved oxygenation and perfusion that has been previously observed with RRx-001 both preclinically and clinically in the context of a brain metastasis trial was correlated with increased penetration and accumulation of the cytotoxic chemotherapies, irinotecan and temozolomide, in orthotopically implanted gliomas, priming tumours for improved response."4.02Vascular priming with RRx-001 to increase the uptake and accumulation of temozolomide and irinotecan in orthotopically implanted gliomas. ( Cabrales, P; Oronsky, B; Reid, T, 2021)
"Temozolomide (TMZ) resistance is the main challenge in the management of glioma patients."4.02Heparanase confers temozolomide resistance by regulation of exosome secretion and circular RNA composition in glioma. ( Cao, L; Chen, Z; Jiang, Z; Li, W; Li, X; Si, J, 2021)
"Glioma stem cells (GSCs) are tumour initiating cells which contribute to treatment resistance, temozolomide (TMZ) chemotherapy and radiotherapy, in glioblastoma (GBM), the most aggressive adult brain tumour."4.02Transcriptional CDK Inhibitors CYC065 and THZ1 Induce Apoptosis in Glioma Stem Cells Derived from Recurrent GBM. ( Düssmann, H; Juric, V; Lamfers, MLM; Murphy, BM; Prehn, JHM; Rehm, M, 2021)
" The nanoantidote, consisting of a dendrimer core wrapped by reductive cysteine, captures Temozolomide (TMZ, the glioblastoma standard chemotherapy)."4.02A Nanoantidote Alleviates Glioblastoma Chemotoxicity without Efficacy Compromise. ( Guan, J; Tian, M; Xing, R; Yang, B; Yang, J; Zhan, C; Zhang, S; Zhao, X, 2021)
"Glioblastoma (GBM) is a malignant brain tumor with a poor long-term prognosis due to recurrence from highly resistant GBM cancer stem cells (CSCs), for which the current standard of treatment with temozolomide (TMZ) alone will unlikely produce a viable cure."4.02Development of CD133 Targeting Multi-Drug Polymer Micellar Nanoparticles for Glioblastoma - In Vitro Evaluation in Glioblastoma Stem Cells. ( Ayyagari, P; Das, SK; Pollok, KE; Shannon, HE; Smiley, SB; Vannier, MW; Veronesi, MC; Yun, Y, 2021)
"To clarify whether differential compartmentalization of Survivin impacts temozolomide (TMZ)-triggered end points, we established a well-defined glioblastoma cell model in vitro (LN229 and A172) and in vivo, distinguishing between its nuclear and cytoplasmic localization."4.02Localization matters: nuclear-trapped Survivin sensitizes glioblastoma cells to temozolomide by elevating cellular senescence and impairing homologous recombination. ( Baymaz, HI; Beli, P; Christmann, M; Mühlhäusler, F; Nikolova, T; Poplawski, A; Reich, TR; Schwarzenbach, C; Tomicic, MT; Unger, S; Vilar, JB, 2021)
"Retrospective data from IDH-wildtype glioblastoma preclinical experiments evaluating a uniform regimen of fractionated radiation (RT), temozolomide (TMZ) chemotherapy, and concurrent RT/TMZ across 27 PDX lines were used to evaluate experimental designs and empirically estimate statistical power for ANOVA and Cox regression."4.02Experimental design of preclinical experiments: number of PDX lines vs subsampling within PDX lines. ( Burgenske, DM; Decker, PA; Eckel-Passow, JE; Kitange, GJ; Kosel, ML; Oberg, AL; Sarkaria, JN, 2021)
"Glioblastoma multiforme (GBM) is the most fatal cancer among brain tumors, and the standard treatment of GBM patients is surgical tumor resection followed by radiotherapy and temozolomide (TMZ) chemotherapy."4.0217β-estradiol induces temozolomide resistance through NRF2-mediated redox homeostasis in glioblastoma. ( Chen, GY; Hsu, SP; Hsu, TI; Hung, CY; Ko, CY; Liao, KH; Lin, HY, 2021)
"Following captopril treatment, MMP-2 protein expression and migratory capabilities of 9 L gliosarcoma cells were assessed in vitro via western blots and scratch wound assays, respectively."4.02Captopril inhibits Matrix Metalloproteinase-2 and extends survival as a temozolomide adjuvant in an intracranial gliosarcoma model. ( Brem, H; Casaos, J; Huq, S; Mangraviti, A; Paldor, I; Perdomo-Pantoja, A; Pinheiro, L; Tyler, B; Vigilar, V; Wang, Y; Witham, TF, 2021)
"To report clinical outcomes of temozolomide (TMZ)-based radio-chemotherapy and adjuvant chemotherapy in patients with aggressive/high-risk low-grade glioma (LGG)."4.02Upfront Therapy of Aggressive/High-Risk Low-Grade Glioma: Single-Institution Outcome Analysis of Temozolomide-Based Radio-Chemotherapy and Adjuvant Chemotherapy. ( Anand, S; Chatterjee, A; Epari, S; Goda, JS; Gupta, T; Jalali, R; Krishnatry, R; Moiyadi, A; Panda, P; Patil, V, 2021)
"A maximal surgical resection followed by radiotherapy and chemotherapy with temozolomide (TMZ) as the representative agent is the standard therapy for gliomas."4.02The function and mechanism of the JARID2/CCND1 axis in modulating glioma cell growth and sensitivity to temozolomide (TMZ). ( Chen, Y; Jiang, W; Kuang, W; Liu, Z; Tian, Y, 2021)
"Apatinib and TMZ may represent an alternative treatment option for patients with recurrent high-gradeglioma, especially those with a low Karnofsky performance status."4.02Clinical study of apatinib plus temozolomide for the treatment of recurrent high-grade gliomas. ( Feng, M; Gan, W; Huang, Y; Li, X; Liu, J; Shao, Y; Wang, X; Yao, H; Zhang, C; Zhou, Y, 2021)
"Intrinsic or acquired resistance to temozolomide (TMZ) is a frequent occurrence in patients with glioblastoma (GBM)."4.02Exosomal transfer of miR‑25‑3p promotes the proliferation and temozolomide resistance of glioblastoma cells by targeting FBXW7. ( Li, T; Wang, B; Wang, J, 2021)
"To evaluate the predictive significance of the duration of temozolomide (TMZ) in patients with glioblastoma multiforme (GBM) who were treated with bevacizumab (Beva) as second-line setting."4.02Is the Duration of Temozolomide Predictive for Sequential Bevacizumab Treatment Responses in the Glioblastoma Multiforme Cancer Setting? ( Besiroglu, M; Demir, T; Shbair, ATM; Topcu, A; Turk, HM; Yasin, AI, 2021)
" We investigated the effects of dopamine in combination with platinum on human glioblastoma U-251MG cells upon X-ray irradiation, comparing with L-DOPA, 2-phenylethylamine and temozolomide."4.02Effects of platinum-coexisting dopamine with X-ray irradiation upon human glioblastoma cell proliferation. ( Kato, S, 2021)
"Improving the chemotherapy resistance of temozolomide (TMZ) is of great significance in the treatment of glioblastoma multiforme (GBM)."4.02Long noncoding RNA just proximal to X-inactive specific transcript facilitates aerobic glycolysis and temozolomide chemoresistance by promoting stability of PDK1 mRNA in an m6A-dependent manner in glioblastoma multiforme cells. ( Jiang, XB; Li, XD; Wang, MJ; Wang, X; Wu, YH; Zheng, JL, 2021)
"Glioblastoma (GBM) is one of the most aggressive primary brain tumors with frequent recurrences following the standard methods of treatment-temozolomide (TMZ), ionizing radiation and surgical resection."3.96TMZ regulates GBM stemness via MMP14-DLL4-Notch3 pathway. ( Gonzalez-Buendia, E; Lesniak, MS; Mijanovic, O; Savchuk, S; Sonabend, A; Timashev, P; Ulasov, IV; Xiao, T, 2020)
"We identified patients newly diagnosed with glioblastoma who were treated with temozolomide-based chemoradiotherapy between 2006 and 2016 at three large-volume hospitals."3.96Validation and optimization of a web-based nomogram for predicting survival of patients with newly diagnosed glioblastoma. ( Chang, JH; Chang, JS; Cho, J; Choe, G; Choi, SH; Hong, CK; Kang, SG; Kim, CY; Kim, E; Kim, EH; Kim, IA; Kim, IH; Kim, JH; Kim, JW; Kim, N; Kim, SH; Kim, TM; Kim, YJ; Lee, HS; Lee, ST; Park, CK; Park, SH; Suh, CO; Wee, CW; Yoon, HI, 2020)
"Standard treatment for glioblastoma (GBM) patients is surgery and radiochemotherapy (RCT) with temozolomide (TMZ)."3.96ABCB1 single-nucleotide variants and survival in patients with glioblastoma treated with radiotherapy concomitant with temozolomide. ( Åkesson, L; Bratthäll, C; Broholm, H; Fomichov, V; Green, H; Grunnet, K; Hallbeck, M; Jakobsen, I; Malmström, A; Milos, P; Mudaisi, M; Papagiannopoulou, A; Poulsen, HS; Söderkvist, P; Stenmark-Askmalm, M; Strandeus, M; Łysiak, M, 2020)
"Temozolomide (TMZ) is one of the most common drugs selected for glioma chemotherapy, but the therapeutic effect of glioma treatment is usually limited due to its resistance."3.96LINC00174 down-regulation decreases chemoresistance to temozolomide in human glioma cells by regulating miR-138-5p/SOX9 axis. ( Chen, M; Li, B; Song, J; Wang, F; Zhao, H, 2020)
" The impact of the chemotherapeutic temozolomide (TMZ) in combination with valproic acid (VPA) was tested in two pediatric glioblastoma-derived cell lines."3.96Musashi1 enhances chemotherapy resistance of pediatric glioblastoma cells in vitro. ( Gielen, G; Hüttelmaier, S; Klusmann, JH; Kramm, C; Kühnöl, CD; Pietsch, T; Pötschke, R, 2020)
"Temozolomide is a first line anti-tumor drug used for the treatment of patients with Glioblastoma multiforme (GBM)."3.96Microarray expression profiles and bioinformatics analysis of mRNAs, lncRNAs, and circRNAs in the secondary temozolomide-resistant glioblastoma. ( Gao, Y; Guo, R; Li, H; Yang, B; Zhao, C, 2020)
"In the EF-14 trial for newly diagnosed glioblastoma (ndGBM) patients addition of Tumour Treating Fields (TTFields) to temozolomide treatment resulted in a significantly improved overall survival (OS)."3.96Tumour Treating Fields (TTFields) in combination with lomustine and temozolomide in patients with newly diagnosed glioblastoma. ( Blau, T; Deuschl, C; Glas, M; Herrlinger, U; Kebir, S; Keyvani, K; Kleinschnitz, C; Lazaridis, L; Oster, C; Pierscianek, D; Schäfer, N; Scheffler, B; Schmidt, T; Stuschke, M; Sure, U; Teuber-Hanselmann, S; Tzaridis, T; Weller, J, 2020)
"In this study, we demonstrated that IKBKE enhances the resistance of glioblastoma cells to temozolomide (TMZ) by activating the AKT/NF-κB signaling pathway to upregulate the expression of the DNA repair enzyme o6-methylguanine-dna methyltransferase (MGMT)."3.96IKBKE enhances TMZ-chemoresistance through upregulation of MGMT expression in glioblastoma. ( Guo, C; Guo, G; Hong, R; Huang, Q; Liu, Y; Lu, J; Lu, Y; Nan, Y; Sun, Y; Xiong, J; Zhang, Z, 2020)
"This analysis aimed to investigate whether the long-term administration of temozolomide (TMZ) claimed a survival advantage for patients with glioblastoma in China."3.96Survival analysis of patients with glioblastoma treated by long-term administration of temozolomide. ( Li, X; Li, Z; Quan, R; Zhang, H, 2020)
"We evaluated clinical and survival data of glioblastoma patients who underwent treatment with bevacizumab after progression under temozolomide, at CHUSJ between 2010 and 2017."3.96Hypertension and proteinuria as clinical biomarkers of response to bevacizumab in glioblastoma patients. ( Caeiro, C; Carvalho, B; Costa, A; Fernandes, AC; Linhares, P; Lopes, RG; Osório, L; Tavares, N; Vaz, R, 2020)
" Here, we detail anti-PD-L1 antibody effects on the tumor microenvironment, including Mϕ infiltration, using a temozolomide (TMZ)-treated glioma model."3.96Infiltration of CD163-positive macrophages in glioma tissues after treatment with anti-PD-L1 antibody and role of PI3Kγ inhibitor as a combination therapy with anti-PD-L1 antibody in in vivo model using temozolomide-resistant murine glioma-initiating cell ( Akutsu, H; Ishikawa, E; Kohzuki, H; Matsuda, M; Matsumura, A; Miyazaki, T; Sakamoto, N; Sugii, N; Takano, S, 2020)
"Chemo-induced thrombocytopenia is a limiting toxicity among patients receiving temozolomide (TMZ) as first-line treatment for glioblastoma."3.96Deleterious impact of a generic temozolomide formulation compared with brand-name product on the kinetic of platelet concentration and survival in newly diagnosed glioblastoma. ( Alexandru, C; Basuyau, F; Clatot, F; Di Fiore, F; Fontanilles, A; Fontanilles, M; Hanzen, C; Joannidès, R; Lamoureux, F; Langlois, O; Massy, N; Pereira, T; Rouvet, J; Tennevet, I, 2020)
"The isocitrate dehydrogenase (IDH) 1 wild-type glioblastoma (GBM) is a major population of GBM that should be of concern in terms of the efficacy of using Temozolomide (TMZ) in adjuvant treatment."3.96Temozolomide for patients with wild-type isocitrate dehydrogenase (IDH) 1 glioblastoma using propensity score matching. ( Sangkhathat, S; Tunthanathip, T, 2020)
"This is the long-term update of NOA-08 (NCT01502241), which compared efficacy and safety of radiotherapy (RT, n = 176) and temozolomide (TMZ, n = 193) at 7/14 days in patients >65 years old with anaplastic astrocytoma or glioblastoma."3.96Superiority of temozolomide over radiotherapy for elderly patients with RTK II methylation class, MGMT promoter methylated malignant astrocytoma. ( Bamberg, M; Bölting, H; Debus, J; Felsberg, J; Herrlinger, U; Hertler, C; Kessler, T; Ketter, R; Mayer-Steinacker, R; Meisner, C; Meixensberger, J; Papsdorf, K; Platten, M; Reifenberger, G; Reuss, D; Sabel, M; Sahm, F; Steinbach, JP; Vesper, J; von Deimling, A; Weisang, S; Weller, M; Weyerbrock, A; Wick, A; Wick, W, 2020)
"Temozolomide (TMZ) is a drug of choice in glioblastoma treatment."3.96Revealing the epigenetic effect of temozolomide on glioblastoma cell lines in therapeutic conditions. ( Barciszewska, AM; Barciszewski, J; Belter, A, 2020)
"Radiotherapy, surgery and the chemotherapeutic agent temozolomide (TMZ) are frontline treatments for glioblastoma multiforme (GBM)."3.96Neurological Impairments in Mice Subjected to Irradiation and Chemotherapy. ( Ahmed, F; Angulo, MC; Baulch, JE; Dey, D; Goldman, J; Klein, PM; Limoli, CL; Merriott, D; Moayyad, J; Murry, A; Nguyen, B; Nguyen, QA; Parihar, VK; Piomelli, D; Soltesz, I; Szabo, GG; Tran, J, 2020)
"Emerging data suggest that a subset of patients with diffuse isocitrate dehydrogenase (IDH)-mutant low-grade glioma (LGG) who receive adjuvant temozolomide (TMZ) recur with hypermutation in association with malignant progression to higher-grade tumors."3.96MGMT promoter methylation level in newly diagnosed low-grade glioma is a predictor of hypermutation at recurrence. ( Berger, MS; Bollam, S; Chang, SM; Clarke, J; Costello, JF; Grimmer, MR; Hong, C; Mathur, R; Molinaro, AM; Oberheim-Bush, NA; Petrecca, K; Phillips, JJ; Zhang, M; Zhang, Y, 2020)
" However, the standard chemotherapy drug for glioma, temozolomide (TMZ), cannot induce ICD as it cannot activate IFN-I signaling."3.96Intranasal Delivery of Immunotherapeutic Nanoformulations for Treatment of Glioma Through in situ Activation of Immune Response. ( Cai, X; Cao, G; Du, B; Hu, J; Ke, C; Li, H; Li, L; Liu, X; Xin, X; Yin, P, 2020)
"Glioblastoma multiforme (GBM) is the most frequent primary brain tumor in adults and Temozolomide (TMZ) is an effective chemotherapeutic agent for its treatment."3.96Reinforcement learning for optimal scheduling of Glioblastoma treatment with Temozolomide. ( Ebrahimi Zade, A; Shahabi Haghighi, S; Soltani, M, 2020)
"Temozolomide (TMZ) resistance is a major cause of recurrence and poor prognosis in glioblastoma (GBM)."3.96LncRNA SOX2OT promotes temozolomide resistance by elevating SOX2 expression via ALKBH5-mediated epigenetic regulation in glioblastoma. ( Chi, Y; Fu, Z; Guo, H; Huang, Q; Lian, C; Liao, C; Liu, B; Wang, C; Wei, Q; Xu, N; Yang, Z; Zeng, H; Zhou, J, 2020)
"To some extent, Si wei xiao xiu yin combined with temozolomide can inhibit the growth of subcutaneous xenografts in glioma nude mice."3.96New advances on the inhibition of Siwei Xiaoliuyin combined with Temozolomide in glioma based on the regulatory mechanism of miRNA21/221. ( Chen, H; Chen, Y; Li, C; Sharma, A; Sharma, HS; Tan, Q; Xie, C; Yang, Y; Zhan, W; Zhang, Z, 2020)
"Temozolomide (TMZ) chemotherapy is a current standard of care for glioblastoma (GBM), however it has only extended overall survival by a few months."3.96Temozolomide antagonizes oncolytic immunovirotherapy in glioblastoma. ( Martuza, RL; Rabkin, SD; Saha, D, 2020)
" Here, diffusion MRI data were acquired in a GL261 glioma mouse model before and during treatment with Temozolomide."3.96Noninvasive diffusion magnetic resonance imaging of brain tumour cell size for the early detection of therapeutic response. ( Agliardi, G; Alexander, DC; Atkinson, D; Brandner, S; Breen-Norris, JO; d'Esposito, A; Hipwell, B; Hyare, H; Ianus, A; Lythgoe, MF; Panagiotaki, E; Punwani, S; Ramasawmy, R; Rees, J; Roberts, TA; Siow, B; Taylor, V; Walker-Samuel, S, 2020)
"Temozolomide is a first line anti-tumor drug used for the treatment of patients with Glioblastoma multiforme (GBM)."3.96MicroRNA-128-3p Enhances the Chemosensitivity of Temozolomide in Glioblastoma by Targeting c-Met and EMT. ( Guan, F; Guo, R; Li, H; Li, M; Liu, X; Ma, S; Wu, J; Yang, B; Zhao, C, 2020)
"Temozolomide (TMZ) is a DNA-alkylating agent used for chemo-radiotherapy of glioblastoma, which is also a target cancer for boron neutron capture therapy (BNCT)."3.96The combined effect of neutron irradiation and temozolomide on glioblastoma cell lines with different MGMT and P53 status. ( Ikawa, T; Kinashi, Y; Takahashi, S, 2020)
"To evaluate the potential prognostic utility of pretreatment systemic immune-inflammation index (SII) in newly diagnosed glioblastoma multiforme (GBM) patients who underwent postneurosurgical radiotherapy and concurrent plus adjuvant temozolomide."3.96Prognostic Value of Pretreatment Systemic Immune-Inflammation Index in Glioblastoma Multiforme Patients Undergoing Postneurosurgical Radiotherapy Plus Concurrent and Adjuvant Temozolomide. ( Besen, AA; Kucuk, A; Mertsoylu, H; Ozdemir, Y; Pehlivan, B; Selek, U; Topkan, E, 2020)
"5, 1 g/kg) or temozolomide (10 mg/kg) treatment alone inhibited tumor growth in glioblastoma U87 and U251 xenografts."3.96Xihuang pill potentiates the anti-tumor effects of temozolomide in glioblastoma xenografts through the Akt/mTOR-dependent pathway. ( Fu, J; Kong, PS; Wang, J; Wang, X; Xu, HB; Xu, YQ; Zhu, SH, 2020)
"Temozolomide (TMZ) is a chemotherapeutic used for the treatment of glioblastoma."3.96A co-formulation of interferons type I and II enhances temozolomide response in glioblastoma with unmethylated MGMT promoter status. ( Bello-Rivero, I; Leenstra, S; van der Kaaij, M; Vázquez-Blomquist, D; Villarreal, A, 2020)
"We designed a conjugated compound by coupling temozolomide (TMZ) with doxorubicin (DOX) via an acylhydrazone linkage as a potential prodrug used for glioblastoma multiforme (GBM) treatment."3.96Temozolomide-Doxorubicin Conjugate as a Double Intercalating Agent and Delivery by Apoferritin for Glioblastoma Chemotherapy. ( Du, K; Feng, F; Heng, H; Xia, Q, 2020)
"Resistance of glioblastoma to the chemotherapeutic compound temozolomide is associated with the presence of glioblastoma stem cells in glioblastoma and is a key obstacle for the poor prognosis of glioblastoma."3.96Phospholipase D1 inhibition sensitizes glioblastoma to temozolomide and suppresses its tumorigenicity. ( Hwang, WC; Kang, DW; Min, DS; Noh, YN; Park, KS, 2020)
"Temozolomide (TMZ) is an oral alkylating agent used for the treatment of glioblastoma and is now becoming a chemotherapeutic option in patients diagnosed with high-risk low-grade gliomas."3.96MGMT genomic rearrangements contribute to chemotherapy resistance in gliomas. ( Bao, Z; Galán-Ganga, M; Jiang, T; Kim, H; Kroon, P; Liu, H; Mu, Q; Nam, DH; Oldrini, B; Rabadan, R; Rodriguez-Perales, S; Sa, JK; Squatrito, M; Vaquero-Siguero, N; Verhaak, RGW; Wang, J; Wang, Z; Zhang, Y; Zhao, J, 2020)
"Temozolomide is the most effective chemotherapy for malignant glioma."3.96Temozolomide desensitization followed by metronomic dosing in patients with hypersensitivity. ( Divekar, RD; Johnson, DR; Maddox, DE; Neth, BJ; Ruff, MW; Uhm, JH, 2020)
"Temozolomide (TMZ) therapy is the standard of care for patients with glioblastoma (GBM)."3.96Preconditioning with INC280 and LDK378 drugs sensitizes MGMT-unmethylated glioblastoma to temozolomide: Pre-clinical assessment. ( Alshareef, M; Cachia, D; Das, A; Infinger, LK; Lindhorst, SM; Patel, SJ; Porto, GBF; Vandergrift, WA; Varma, AK, 2020)
" Concurrent temozolomide (TMZ) radiation-the cornerstone of glioma control-extends the overall median survival of GB patients by only a few months over radiotherapy alone."3.96Developing a clinically relevant radiosensitizer for temozolomide-resistant gliomas. ( Chen, TC; Cho, HY; Duc, TC; Hartman, H; Hofman, FM; Huang, M; Minea, RO; Schönthal, AH; Swenson, SD, 2020)
" In glioblastoma (GBM), predictive biomarkers of cellular responses to temozolomide (TMZ) combined with poly‑ADP‑ribose polymerase inhibitor (PARPi) remain largely unidentified."3.96PARP‑1 inhibition sensitizes temozolomide‑treated glioblastoma cell lines and decreases drug resistance independent of MGMT activity and PTEN proficiency. ( Godoy, PRDV; Lima, SCG; Montaldi, AP; Sakamoto-Hojo, ET; Xavier, DJ, 2020)
"Glioma is the most common primary malignant tumour in the brain; temozolomide (TMZ) is the most prevalent chemotherapeutic drug currently used to combat this cancer."3.96LINC00470 promotes tumour proliferation and invasion, and attenuates chemosensitivity through the LINC00470/miR-134/Myc/ABCC1 axis in glioma. ( Li, Y; Liu, Q; Long, W; Pan, Y; Qin, C; Su, J; Wang, J; Wang, X; Wu, C; Xiao, K; Xiao, Q, 2020)
" The transfection efficiency was determined with flow cytometry, and the therapeutic efficacy of CD::UPRT::GFP expressing MSCs was evaluated in cocultures with temozolomide (TMZ)-sensitive or TMZ-resistant human glioblastoma cell lines."3.96A facile and scalable in production non-viral gene engineered mesenchymal stem cells for effective suppression of temozolomide-resistant (TMZR) glioblastoma growth. ( Ho, YK; Ng, ZX; Teo, KJ; Too, HP; Tu, GXE; Yeo, TT, 2020)
"To assess the patterns of failure and prognostic factors in Brazilian patients with glioblastoma multiforme (GBM) treated with radiotherapy (RT) and concurrent and adjuvant temozolomide (TMZ)."3.96Patterns of recurrence and outcomes of glioblastoma multiforme treated with chemoradiation and adjuvant temozolomide. ( Faustino, AC; Hamamura, AC; Viani, GA, 2020)
" In this study, we explore whether CAP, an ionized gas produced in laboratory settings and that operates at near room temperature, can enhance Temozolomide (TMZ) cytotoxicity on a glioblastoma cell line (U87MG)."3.96Combination therapy of cold atmospheric plasma (CAP) with temozolomide in the treatment of U87MG glioblastoma cells. ( Gjika, E; Keidar, M; Kirschner, ME; Lin, L; Pal-Ghosh, S; Sherman, JH; Stepp, MA, 2020)
"Glioma, especially glioblastoma (GBM), is the most aggressive malignant brain tumor and its standard therapy is often ineffective because of temozolomide (TMZ) resistance."3.96Combination of levetiracetam and IFN-α increased temozolomide efficacy in MGMT-positive glioma. ( Cai, HP; Chen, FR; Chen, ZP; Guo, CC; Ma, JX; Ni, XR; Wang, J; Wu, WC; Yu, YJ; Yu, ZH, 2020)
"Despite aggressive treatment with temozolomide and radiotherapy and extensive research into alternative therapies there has been little improvement in Glioblastoma patient survival."3.96Reduced EGFR and increased miR-221 is associated with increased resistance to temozolomide and radiotherapy in glioblastoma. ( Areeb, Z; Gomez, J; Jones, J; Kaye, AH; Luwor, RB; Morokoff, AP; Nguyen, HPT; Paradiso, L; Stuart, SF; West, AJ; Zulkifli, A, 2020)
"Glioblastoma (GBM) is a malignant brain tumour with a dismal prognosis, despite best treatment by surgical resection, radiation therapy (RT) and chemotherapy with temozolomide (TMZ)."3.96Cytotoxic lanthanum oxide nanoparticles sensitize glioblastoma cells to radiation therapy and temozolomide: an in vitro rationale for translational studies. ( Jue, TR; Lu, VM; McDonald, KL, 2020)
" This prospective study included 52 consecutive newly diagnosed glioblastoma (n = 49) or gliosarcoma (n = 3) patients treated with concomitant temozolomide and radiotherapy (RT-TMZ), followed by a TMZ maintenance phase."3.96Cell-free DNA and circulating TERT promoter mutation for disease monitoring in newly-diagnosed glioblastoma. ( Alexandru, C; Beaussire, L; Clatot, F; Di Fiore, F; Fontanilles, M; Hanzen, C; Jardin, F; Langlois, O; Laquerrière, A; Magne, N; Marguet, F; Pépin, LF; Sarafan-Vasseur, N; Tennevet, I, 2020)
"Objective To investigate the expression of cathepsin S (CTSS) in temozolomide-resistant glioblastoma T98G (T98G-R) cells."3.96[Cathepsin S (CTSS) is highly expressed in temozolomide-resistant glioblastoma T98G cells and associated with poor prognosis]. ( Guo, Q; Jia, B; Liu, W; Lyu, W, 2020)
" However, the function of circ_0005198 in the temozolomide (TMZ) resistance of glioma has not been well elucidated."3.96Circ_0005198 enhances temozolomide resistance of glioma cells through miR-198/TRIM14 axis. ( Deng, Y; Liu, C; Meng, X; Xiao, L; Zhu, H, 2020)
" In this study, we investigated whether selective add-on BEV for patients with newly diagnosed glioblastoma (GBM) and anaplastic astrocytoma (AA) improves prognosis, in cases where tumors were continuously growing during radiotherapy concomitant with temozolomide (TMZ)."3.96The prognostic improvement of add-on bevacizumab for progressive disease during concomitant temozolomide and radiation therapy in patients with glioblastoma and anaplastic astrocytoma. ( Hirata, K; Houkin, K; Ishi, Y; Kobayashi, H; Motegi, H; Oda, Y; Okamoto, M; Tanaka, S; Terasaka, S; Yamaguchi, S, 2020)
" The potential importance of the detected metabolic heterogeneity was tested in three glioma cell lines (grade III-IV) using protein expression analyses (Western blot and WES Simple) and therapeutic drug (temozolomide), metabolic inhibitor treatments (including glutaminase inhibitor) to compare the effects of rapamycin (RAPA) and glutaminase inhibitor combinations in vitro (Alamar Blue and SRB tests)."3.96Inhibition of Metabolic Shift can Decrease Therapy Resistance in Human High-Grade Glioma Cells. ( Dankó, T; Hujber, Z; Jeney, A; Krencz, I; Pápay, J; Petővári, G; Raffay, R; Rajnai, H; Sebestyén, A; Vetlényi, E, 2020)
"The natural product primary sulfonamide, psammaplin C (1), when used in combination with clinically used chemotherapeutic drugs, including temozolomide, reverses multidrug resistance and increases survival in glioblastoma, a highly aggressive primary brain tumor."3.91Carbonic Anhydrase XII Inhibitors Overcome Temozolomide Resistance in Glioblastoma. ( Bua, S; Kopecka, J; Mujumdar, P; Poulsen, SA; Riganti, C; Supuran, CT, 2019)
" We identified hybrid compounds 1d and 1e to be remarkably more potent against glioma and more efficient in decreasing invasive cell properties than temozolomide and endowed with chemical and plasma stability."3.91Targeting gliomas with triazene-based hybrids: Structure-activity relationship, mechanistic study and stability. ( Braga, C; Brites, D; Matilde Marques, M; Moreira, R; Oliveira, MC; Perry, MJ; Vaz, AR, 2019)
"Temozolomide (TMZ) is a first-line chemotherapeutic agent used against glioblastoma multiforme (GBM), but this disease exhibits recurrence and high lethality."3.91miR-140 targeting CTSB signaling suppresses the mesenchymal transition and enhances temozolomide cytotoxicity in glioblastoma multiforme. ( Chen, KC; Chen, PH; Cheng, CH; Chou, CM; Ho, KH; Lin, CW; Liu, AJ; Shih, CM, 2019)
"Temozolomide is an alkylating agent used as the first line of treatment for glioblastoma."3.91Temozolomide has anti-tumor effects through the phosphorylation of cPLA ( Hara, H; Iwama, T; Nakamura, S; Noda, Y; Ohno, Y; Saio, M; Shimazawa, M; Tsuji, S; Yamada, T, 2019)
"Our study elucidated the role of oncogenic LINC01198 in glioma proliferation and temozolomide resistance, and this role may serve as a promising target for glioma therapy."3.91LINC01198 promotes proliferation and temozolomide resistance in a NEDD4-1-dependent manner, repressing PTEN expression in glioma. ( Chen, HJ; Chen, WL; Ge, JW; Hou, GQ; Zhang, XH, 2019)
" In this study, we investigate the underlying mechanism by which glioblastoma (GBM) cells acquire resistance to Temozolomide (TMZ) through Aurora kinase B (AURKB) thus to identify novel therapeutic targets and prognostic biomarkers for GBM."3.91Targeting Aurora kinase B attenuates chemoresistance in glioblastoma via a synergistic manner with temozolomide. ( Alafate, W; Liu, C; Sun, L; Wang, J; Wang, M; Wu, W; Xie, W; Zuo, J, 2019)
" However, the role of circular RNA CEP128 in the resistance of glioma cells to temozolomide has not yet been characterized."3.91Knockdown of circular RNA CEP128 suppresses proliferation and improves cytotoxic efficacy of temozolomide in glioma cells by regulating miR-145-5p. ( Feng, H; Hua, L; Huang, L; Shen, B; Zhang, X, 2019)
"To investigate the underlying mechanism by which glioblastoma (GBM) cells gain temozolomide (TMZ) resistance and to clarify novel therapeutic targets and new prognostic biomarkers for GBM."3.91Nuclear factor I A promotes temozolomide resistance in glioblastoma via activation of nuclear factor κB pathway. ( Li, R; Mao, P; Wahafu, A; Wang, J; Wang, M; Wu, W; Xie, W; Yu, X; Zuo, J, 2019)
"Current treatment of recurrent glioblastoma multiforme (GBM) demands dose-intense temozolomide (TMZ), a prodrug of 5-(3-methyltriazen-1-yl) imidazole-4-carboxamide (MTIC), based on the spontaneous hydrolysis of TMZ at basic pH."3.91Enhanced Copper-Temozolomide Interactions by Protein for Chemotherapy against Glioblastoma Multiforme. ( Du, K; Feng, F; Li, X; Shao, F; Sun, J; Sun, Y, 2019)
"Drug resistance to temozolomide (TMZ) contributes to the majority of tumor recurrence and treatment failure in patients with glioblastoma multiforme (GBM)."3.91Lovastatin Enhances Cytotoxicity of Temozolomide via Impairing Autophagic Flux in Glioblastoma Cells. ( Cheng, SY; Kiang, KMY; Leung, GK; Li, N; Wong, VK; Zhang, P; Zhu, Z, 2019)
"The purpose of this study was to evaluate the outcomes of elderly patients (aged ≥75 years) with newly diagnosed glioblastoma (GBM), who were treated with hypofractionated radiotherapy comprising 45 Gy in 15 fractions combined with temozolomide (TMZ) or TMZ and bevacizumab (TMZ/Bev)."3.91Survival benefits of hypofractionated radiotherapy combined with temozolomide or temozolomide plus bevacizumab in elderly patients with glioblastoma aged ≥ 75 years. ( Ichimura, K; Igaki, H; Matsushita, Y; Miyakita, Y; Narita, Y; Ohno, M; Takahashi, M, 2019)
"Temozolomide (TMZ) is the most commonly used chemotherapeutic agent used to treat glioblastoma (GBM), which causes significant DNA damage to highly proliferative cells."3.91Inhibition of phosphatidylinositol 3-kinase by PX-866 suppresses temozolomide-induced autophagy and promotes apoptosis in glioblastoma cells. ( Harder, BG; Kitange, GJ; Loftus, JC; Peng, S; Sarkaria, JN; Sereduk, CP; Sodoma, AM; Tran, NL, 2019)
"In the management of patients with newly diagnosed glioblastoma, there is no standard duration for adjuvant temozolomide treatment."3.91Feasibility study of finalizing the extended adjuvant temozolomide based on methionine positron emission tomography (Met-PET) findings in patients with glioblastoma. ( Hasegawa, Y; Hatano, K; Hirono, S; Iuchi, T; Sakaida, T; Uchino, Y, 2019)
"Bortezomib was found to inhibit glioma growth and improved TMZ chemotherapy efficacy, probably via down-regulating the FOXM1-Survivin axis."3.91Bortezomib inhibits growth and sensitizes glioma to temozolomide (TMZ) via down-regulating the FOXM1-Survivin axis. ( Chen, JX; Du, L; Huang, GH; Li, QR; Lv, SQ; Tang, JH; Xiang, Y; Xu, QF; Yang, L; Zhang, ZX; Zhou, Z; Zhu, LR, 2019)
"Current standard of treatment for newly diagnosed patients with glioblastoma (GBM) is surgical resection with adjuvant normofractionated radiotherapy (NFRT) combined with temozolomide (TMZ) chemotherapy."3.91Accelerated hyperfractionated radiochemotherapy with temozolomide is equivalent to normofractionated radiochemotherapy in a retrospective analysis of patients with glioblastoma. ( Flentje, M; Klement, RJ; Kosmala, R; Lewitzki, V; Lisowski, D; Polat, B, 2019)
"Temozolomide (TMZ) is known to induce thrombocytopenia but no early predictive test has yet been clearly established."3.91Early platelet variation during concomitant chemo-radiotherapy predicts adjuvant temozolomide-induced thrombocytopenia in newly diagnosed glioblastoma patients. ( Alexandru, C; Clatot, F; David, M; Di Fiore, F; Fontanilles, M; Gilard, V; Hanzen, C; Langlois, O; Laquerriere, A; Marguet, F; Tennevet, I; Veresezan, O, 2019)
"Oxygen 6-methylguanine-DNA methyltransferase (MGMT) promoter methylation is a significant prognostic biomarker in astrocytomas, especially for temozolomide (TMZ) chemotherapy."3.91A multi-sequence and habitat-based MRI radiomics signature for preoperative prediction of MGMT promoter methylation in astrocytomas with prognostic implication. ( Dong, D; Gu, D; Hao, X; Tan, Y; Tian, J; Wang, L; Wang, X; Wei, J; Yang, G; Zhang, H; Zhang, S, 2019)
"Glioblastoma multiforme (GBM) has a poor prognosis with an overall survival of 14-15 months after surgery, radiation and chemotherapy using temozolomide (TMZ)."3.91Thioridazine inhibits autophagy and sensitizes glioblastoma cells to temozolomide. ( Bjerkvig, R; Denisova, O; Grudic, A; Hasan-Olive, MM; Janji, B; Johannessen, TC; Latif, MA; Lund-Johansen, M; Nordal, A; Prestegarden, L; Røsland, GV; Saed, H; Simonsen, A; Sundstrøm, T; Tronstad, KJ; Varughese, JK; Wang, J; Westermarck, J; Yang, N; Zhu, H, 2019)
"The aromatase inhibitor, letrozole, is being investigated in experimental animal models as a novel treatment for high-grade gliomas (HGGs)."3.91Plasma and brain pharmacokinetics of letrozole and drug interaction studies with temozolomide in NOD-scid gamma mice and sprague dawley rats. ( Adams, CH; Arora, P; DasGupta, B; Desai, PB; Gudelsky, G, 2019)
" In the EF-14 phase 3 trial in newly diagnosed glioblastoma, TTFields plus temozolomide (TTFields/TMZ) improved progression free (PFS) and overall survival (OS) versus TMZ alone."3.91Increased compliance with tumor treating fields therapy is prognostic for improved survival in the treatment of glioblastoma: a subgroup analysis of the EF-14 phase III trial. ( Kim, CY; Nicholas, G; Ram, Z; Toms, SA, 2019)
"To describe oncological patterns of care, prognostic factors, and survival for all patients in France with newly-diagnosed and histologically confirmed glioblastoma, and evaluate the impact of extended temozolomide use at the population level."3.91Association of patterns of care, prognostic factors, and use of radiotherapy-temozolomide therapy with survival in patients with newly diagnosed glioblastoma: a French national population-based study. ( Amelot, A; Bauchet, F; Bauchet, L; Bessaoud, F; Charissoux, M; Darlix, A; Duffau, H; Fabbro, M; Fabbro-Peray, P; Figarella-Branger, D; Mandonnet, E; Mathieu-Daude, H; Pallud, J; Rigau, V; Riondel, A; Sorbets, E; Taillandier, L; Tretarre, B; Zouaoui, S, 2019)
"Despite the clinical success of temozolomide (TMZ), its sensitivity remains a major challenge in glioblastoma (GBM)."3.91PLK4 is a determinant of temozolomide sensitivity through phosphorylation of IKBKE in glioblastoma. ( Han, L; Huang, K; Liang, H; Liu, Y; Wang, G; Wang, Q; Wang, Z; Wei, C; Zhang, A; Zhang, W; Zhang, Z; Zhen, Y; Zhou, J, 2019)
"Chemotherapy is the main postsurgical and adjuvant therapy for glioma, and intrinsic or acquired temozolomide (TMZ) resistance may result in poor prognosis."3.91MiR-181b-5p modulates chemosensitivity of glioma cells to temozolomide by targeting Bcl-2. ( Feng, B; Ren, H; Wang, J; Yu, J; Yuan, Z; Zhang, B; Zhang, X; Zhao, C; Zhuang, J, 2019)
"At present, there is no uniform consensus on the treatment of recurrent glioblastoma, especially the re-irradiation dose and temozolomide (TMZ) dose."3.91Conventionally fractionated stereotactic radiotherapy (CFRT) in combination with dose-dense temozolomide (TMZ) in relapsed malignant glioma: A case report. ( Li, Y; Qie, S; Shi, HY; Yuan, L; Zhang, X, 2019)
"For our studies, we have particularly chosen C6 rat glioma cell line due to several reasons: i) We previously showed that MPA reduced growth and induced procarbazine-sensitization in C6 cells; ii) temozolomide has a triazene-type molecular structure like procarbazine; iii) other groups previously showed that C6 glioma cell line is more resistant to temozolomide than human glioma cells; hence it may provide a native model of chemoresistance."3.91Medroxyprogesterone effects on colony growth, autophagy and mitochondria of C6 glioma cells are augmented with tibolone and temozolomide: Cell kinetic and electron microscopical studies with a broad review of the literature. ( Altinoz, MA; Bilir, A; Elmaci, İ; Ozpinar, A, 2019)
"Chemotherapy with temozolomide (TMZ) is the traditional treatment for glioblastoma (GBM)."3.91MCCK1 enhances the anticancer effect of temozolomide in attenuating the invasion, migration and epithelial-mesenchymal transition of glioblastoma cells in vitro and in vivo. ( Li, A; Liu, T; Xin, Y; Xu, Y, 2019)
"Temozolomide (TMZ) is a widely used chemotherapeutic agent for glioblastoma multiforme (GBM)."3.91Momelotinib sensitizes glioblastoma cells to temozolomide by enhancement of autophagy via JAK2/STAT3 inhibition. ( Li, A; Liu, T; Xin, Y; Xu, Y, 2019)
" Temozolomide is the most common chemotherapy used to treat glioblastoma (GBM) and has been shown to have variable effects on immune response to immunotherapy."3.91Modulation of temozolomide dose differentially affects T-cell response to immune checkpoint inhibition. ( Azari, H; Dastmalchi, F; Flores, C; Huang, J; Karachi, A; Long, Y; Mitchell, DA; Rahman, M; Sayour, EJ; Yang, C, 2019)
"Despite advances in cancer therapies, glioblastoma multiforme treatment remains inefficient due to the brain-blood barrier (BBB) inhibitory activity and to the low temozolomide (TMZ) chemotherapeutic selectivity."3.91Targeted and Synergic Glioblastoma Treatment: Multifunctional Nanoparticles Delivering Verteporfin as Adjuvant Therapy for Temozolomide Chemotherapy. ( de Melo, MT; Paula, LB; Pellosi, DS; Tedesco, AC, 2019)
"Despite intensive treatments including temozolomide (TMZ) administration, glioblastoma patient prognosis remains dismal and innovative therapeutic strategies are urgently needed."3.91pH as a potential therapeutic target to improve temozolomide antitumor efficacy : A mechanistic modeling study. ( Ballesta, A; Stéphanou, A, 2019)
"Standard-of-care treatment of glioblastomas involves maximal safe resection and adjuvant temozolomide chemo-radiotherapy."3.91Determining a cut-off residual tumor volume threshold for patients with newly diagnosed glioblastoma treated with temozolomide chemoradiotherapy: A multicenter cohort study. ( Chan, DTM; Chan, KY; Ho, JMK; Lam, SW; Lee, MWY; Mak, CHK; Poon, WS; Tse, TPK; Wong, ST; Woo, PYM, 2019)
"The aims of the present study were to compare the longitudinal changes of glioblastoma multiforme after radiotherapy (RT) between 11C-methionine positron emission tomography (MET-PET) and gadolinium (Gd)-enhanced magnetic resonance imaging (MRI) and to clarify whether these changes were predictive of survival."3.91Dissociation Between 11C-Methionine-Positron Emission Tomography and Gadolinium-Enhanced Magnetic Resonance Imaging in Longitudinal Features of Glioblastoma After Postoperative Radiotherapy. ( Asano, Y; Ikegame, Y; Iwama, T; Kawasaki, T; Miwa, K; Shinoda, J; Takei, H; Yano, H; Yokoyama, K, 2019)
"We identified DDIT4 as a cell-intrinsic regulator for adaptive responses and therapy resistance in glioblastoma cells which may interfere with cell death induction by temozolomide, radiotherapy or hypoxia by inhibiting mTORC1 activity."3.91The physiological mTOR complex 1 inhibitor DDIT4 mediates therapy resistance in glioblastoma. ( Foltyn, M; Harter, PN; Lorenz, NI; Luger, AL; Mittelbronn, M; Ronellenfitsch, MW; Sauer, B; Steinbach, JP, 2019)
"Tumor recurrence in glioblastoma multiforme (GBM) is often attributed to acquired resistance to the standard chemotherapeutic agent, temozolomide (TMZ)."3.91Glioblastoma Recurrence and the Role of O ( Ahmed, AU; Foo, J; Hawkins-Daarud, A; Leder, K; Rockne, RC; Storey, K; Swanson, K, 2019)
"Together, our findings reveal the indispensable role of HERC3 in regulating canonical SMAD2/3-dependent TGFβ pathway involvement in autophagy-induced EMT, providing insights toward a better understanding of the mechanism of resistance to temozolomide and peripheral recurrence of glioblastoma."3.91HERC3-Mediated SMAD7 Ubiquitination Degradation Promotes Autophagy-Induced EMT and Chemoresistance in Glioblastoma. ( Chen, L; Hu, Z; Huang, A; Li, H; Li, J; Lu, Y; Ma, L; Qi, S; Shi, L; Weng, Z; Xin, Z; Yu, S; Zhou, Q, 2019)
"When only treated with D,L-methadone, 1 µM of the opioid was sufficient to reduce viability of fibroblasts, whereas 10 µM was needed to significantly reduce glioblastoma cell viability."3.91D,L-Methadone does not improve radio- and chemotherapy in glioblastoma in vitro. ( Baran-Schmidt, R; Dietterle, J; Gaunitz, F; Glasow, A; Matusova, M; Meixensberger, J; Neumann, K; Oppermann, H, 2019)
"Both of the temozolomide (TMZ)-resistant and CtIP deficient glioma cell lines were successfully generated."3.91CtIP contributes to non-homologous end joining formation through interacting with ligase IV and promotion of TMZ resistance in glioma cells. ( Han, N; Jiang, H; Sun, J; Xu, HY; Yang, B, 2019)
"Although temozolomide (TMZ) resistance is a significant clinical problem in glioblastoma (GBM), its underlying molecular mechanisms are poorly understood."3.91Exosomal transfer of miR-1238 contributes to temozolomide-resistance in glioblastoma. ( Shi, Z; Yan, W; Yin, J; You, Y; Zeng, A; Zhang, Z, 2019)
"Temozolomide (TMZ) is an alkylating agent used in the treatment of high-grade malignant glioma, notably glioblastoma multiforme, the most aggressive form of brain cancer."3.91Are There Thresholds in Glioblastoma Cell Death Responses Triggered by Temozolomide? ( He, Y; Kaina, B, 2019)
" In this preliminary study, the purpose was to evaluate the feasibility of APT imaging in monitoring the early therapeutic response to nitroxoline (NTX) in a temozolomide (TMZ)-resistant glioblastoma multiforme (GBM) mouse model, which was compared with diffusion-weighted imaging (DWI)."3.91Assessment of Early Therapeutic Response to Nitroxoline in Temozolomide-Resistant Glioblastoma by Amide Proton Transfer Imaging: A Preliminary Comparative Study with Diffusion-weighted Imaging. ( Cho, HR; Choi, SH; Kumari, N; Thakur, N, 2019)
" Following tumor resection, the patient underwent concomitant radiation and temozolomide therapy that was complicated by CMV colitis and abdominal abscesses."3.91Long-term glioblastoma survival following recovery from cytomegalovirus colitis: A case report. ( Bloch, O; Grimm, SA; Horbinski, CM; Kumthekar, PU; Lamano, JB; Quaggin-Smith, JA; Tate, MC, 2019)
"The acquired drug resistance has been regarded as a main barrier for the effective treatment of temozolomide (TMZ) in glioblastoma (GBM)."3.91miR-126-3p sensitizes glioblastoma cells to temozolomide by inactivating Wnt/β-catenin signaling via targeting SOX2. ( Li, X; Liu, X; Luo, W; Song, Z; Yan, D; Zhao, S; Zhu, X, 2019)
"The aim of this current work was to study the therapeutic enhancement of temozolomide (TMZ) on gliomavia combining with calycosin and FMN."3.91In vitro and in vivo Study on Glioma Treatment Enhancement by Combining Temozolomide with Calycosin and Formononetin. ( Fan, H; Fan, Y; Li, Y; Ni, Q; Zhang, X, 2019)
"Constructed from a theoretical framework, the coordinated undermining of survival paths in glioblastoma (GBM) is a combination of nine drugs approved for non-oncological indications (CUSP9; aprepitant, auranofin, captopril, celecoxib, disulfiram, itraconazole, minocycline, quetiapine, and sertraline) combined with temozolomide (TMZ)."3.91The efficacy of a coordinated pharmacological blockade in glioblastoma stem cells with nine repurposed drugs using the CUSP9 strategy. ( Grieg, Z; Langmoen, IA; Sandberg, CJ; Skaga, E; Skaga, IØ; Vik-Mo, EO, 2019)
" However, the mechanisms underlying lncRNA-mediated temozolomide (TMZ) resistance in glioblastoma (GBM) remain largely unknown."3.91Lnc-TALC promotes O ( Cai, J; Chen, Q; Duan, C; Han, B; Jiang, C; Kang, C; Li, Y; Li, Z; Lin, L; Meng, X; Wang, R; Wu, P, 2019)
"Temozolomide (TMZ) is widely used as a chemotherapeutic agent in the treatment of glioma; however, the development of drug resistance remains a major obstacle in the effective treatment of glioblastoma."3.91Downregulation of miR‑186 promotes the proliferation and drug resistance of glioblastoma cells by targeting Twist1. ( Chen, R; Tu, Y; Wang, C; Wang, L; Wang, S; Xiong, Y; Zhu, L, 2019)
"To identify novel epigenetic signatures that could provide predictive information that is complementary to promoter methylation status of the O-6-methylguanine-DNA methyltransferase (MGMT) gene for predicting temozolomide (TMZ) response, among glioblastomas (GBMs) without glioma-CpGs island methylator phenotype (G-CIMP) METHODS: Different cohorts of primary non-G-CIMP GBMs with genome-wide DNA methylation microarray data were included for discovery and validation of a multimarker signature, combined using a RISK score model."3.91Novel predictive epigenetic signature for temozolomide in non-G-CIMP glioblastomas. ( Aubry, M; Barnholtz-Sloan, J; Etcheverry, A; He, YL; Liu, BL; Liu, YH; Lu, ZF; Mosser, J; Yin, AA; Zhang, X, 2019)
"Gene signatures (GS) were developed from 31 orthotopic glioblastoma patient-derived xenografts (PDXs), treated with standard therapies, to predict benefit from radiotherapy (RT-GS), temozolomide (Chemo-GS), or the combination (ChemoRT-GS)."3.91Xenograft-based, platform-independent gene signatures to predict response to alkylating chemotherapy, radiation, and combination therapy for glioblastoma. ( Carlson, BL; Chang, SL; Feng, FY; Kim, MM; Lawrence, TS; Mladek, AC; Sarkaria, JN; Speers, CW; Spratt, DE; Wahl, DR; Yu, M; Zhao, SG, 2019)
"Despite the increased understanding of the oncological mechanisms underlying Glioblastoma multiforme (GBM) pathophysiology, and recent advances in therapeutic strategies such as maximal surgical resection and post-operative radiotherapy with concomitant and adjuvant temozolomide chemotherapy, the prognosis for patients with brain tumors remains limited."3.91microRNA-181d associated with the methylation status of the MGMT gene in Glioblastoma multiforme cancer stem cells submitted to treatments with ionizing radiation and temozolomide. ( Carlotti, CG; de Assis Cirino, ML; Lizarte Neto, FS; Matias, CCMS; Pereira-da-Silva, G; Peria, FM; Rodrigues, AR; Tirapelli, DPDC; Trevisan, FA, 2019)
"We formulated an ultra-small, gadolinium-based nanoparticle (AGuIX) with theranostic properties to simultaneously enhance MRI tumor delineation and radiosensitization in a glioma model."3.91Ultrasmall theranostic gadolinium-based nanoparticles improve high-grade rat glioma survival. ( Appelboom, G; Barbier, EL; Bräuer-Krisch, E; Chang, SD; Dufort, S; Le Duc, G; Lux, F; Roux, S; Sancey, L; Tillement, O; Verry, C; Zhang, M, 2019)
"The acquisition of temozolomide resistance is a major clinical challenge for glioblastoma treatment."3.91Acquired temozolomide resistance in MGMT-deficient glioblastoma cells is associated with regulation of DNA repair by DHC2. ( Chen, Z; Deng, S; Guo, M; Huang, G; Lei, B; Li, Y; Li, Z; Liu, Y; Pan, J; Qi, S; Wang, H; Xiang, W; Yi, GZ; Yu, L; Zhang, X, 2019)
"This study aimed to screen in vitro antitumour activity of the redox couple avarol/avarone against the human malignant glioma cell line U-251 MG for the first time."3.88The redox couple avarol/avarone in the fight with malignant gliomas: the case study of U-251 MG cells. ( Glumac, M; Jakimov, D; Kojic, V; Pejin, B; Tommonaro, G, 2018)
"Glioblastoma (GBM) is an aggressive brain tumor with temozolomide (TMZ)-based chemotherapy as the main therapeutic strategy."3.88Low Dose of Doxorubicin Potentiates the Effect of Temozolomide in Glioblastoma Cells. ( Kipper, FC; Lenz, G; Lopez, PLDC; Silva, AO; Villodre, ES, 2018)
"We evaluated stereotactic volume modulated arc radiotherapy (VMAT) for canine gliomas, alone (radiotherapy [RT]) and in combination with temozolomide (RT + TMZ), compared with palliation."3.88Frameless stereotactic radiotherapy alone and combined with temozolomide for presumed canine gliomas. ( Bianchi, C; Carrara, N; Dolera, M; Finesso, S; Malfassi, L; Marcarini, S; Mazza, G; Pavesi, S; Sala, M; Urso, G, 2018)
"Standard treatment for patients with primary glioblastoma (GBM) includes surgery, radiotherapy, and concomitant and adjuvant temozolomide (TMZ)."3.88Prognostic importance of temozolomide-induced neutropenia in glioblastoma, IDH-wildtype patients. ( Hama, S; Kawamata, T; Kurisu, K; Muragaki, Y; Nosaka, R; Saito, T; Sugiyama, K; Takayasu, T; Yamasaki, F, 2018)
"Evaluate survival of patients diagnosed with glioblastoma multiforme (GBM) managed with adjuvant intensity modulated radiation therapy and temozolomide since the introduction of the European Organisation for Research and Treatment of Cancer and National Cancer Institute of Canada Clinical Trials Group (EORTC-NCIC) protocol."3.88Survival improvements with adjuvant therapy in patients with glioblastoma. ( Back, MF; Brazier, D; Cook, R; Guo, L; Jayamanne, D; Kastelan, M; Schembri, G; Teo, C; Wheeler, H, 2018)
"Our study tested the diagnostic accuracy of increased signal intensity (SI) within FLAIR MR images of resection cavities in differentiating early progressive disease (ePD) from pseudoprogression (PsP) in patients with glioblastoma treated with radiotherapy with concomitant temozolomide therapy."3.88Increased signal intensity within glioblastoma resection cavities on fluid-attenuated inversion recovery imaging to detect early progressive disease in patients receiving radiotherapy with concomitant temozolomide therapy. ( Agrawal, JP; Erickson, BJ; Korfiatis, P; Perry, LA, 2018)
" By manipulation of Cx43 expression or gap junction function, we found that there were gap junction-dependent and independent effect of Cx43 on temozolomide (TMZ) sensitivity in U87 glioblastoma cells."3.88Tramadol attenuates the sensitivity of glioblastoma to temozolomide through the suppression of Cx43‑mediated gap junction intercellular communication. ( Huang, H; Ma, L; Peng, J; Peng, Y; Shao, M; Wang, L; Xia, Z; Zhong, G; Zhu, Z, 2018)
"Numerous studies suggested autophagy was involved in temozolomide (TMZ) resistance in glioma."3.88Upregulation of CASC2 sensitized glioma to temozolomide cytotoxicity through autophagy inhibition by sponging miR-193a-5p and regulating mTOR expression. ( Du, J; Fang, X; Huang, X; Jiang, C; Li, X; Liu, Z; Shen, F; Su, J; Wang, X, 2018)
"Although upfront temozolomide (TMZ) has been widely-used to treat 1p/19q-codeleted diffuse low-grade gliomas (LGG), its long-term impact on the growth kinetics of these tumors has not been determined."3.88Long-term impact of temozolomide on 1p/19q-codeleted low-grade glioma growth kinetics. ( Alentorn, A; Barritault, M; Bruna, J; Delattre, JY; Ducray, F; Honnorat, J; Idbaih, A; Izquierdo, C; Kaloshi, G; Meyronet, D; Ricard, D; Simó, M, 2018)
"The purpose of the study is to investigate the efficacy of combined treatment with temozolomide (TMZ) and metformin for glioblastoma (GBM) in vitro and in vivo."3.88High-Dose Metformin Plus Temozolomide Shows Increased Anti-tumor Effects in Glioblastoma In Vitro and In Vivo Compared with Monotherapy. ( Hong, YK; Lee, JE; Lim, JH; Yang, SH, 2018)
"The impact of DNA mismatch repair (MMR) on resistance to temozolomide (TMZ) therapy in patients with glioblastoma (GBM) is recently reported but the mechanisms are not understood."3.88Up-regulation of MSH6 is associated with temozolomide resistance in human glioblastoma. ( Dong, T; Dong, Y; Gao, Y; Gong, Y; Li, Q; Pei, C; Ren, H; Su, J; Sun, Q; Xiao, Y; Xing, W; Zhen, Z; Zhou, P, 2018)
"0 years) diagnosed with glioblastoma undergoing adjuvant photon (n = 47) or proton (n = 19) radiochemotherapy with temozolomide after tumor resection underwent T1-weighted and arterial spin labeling MRI."3.88Photon vs. proton radiochemotherapy: Effects on brain tissue volume and perfusion. ( Asllani, I; Baumann, M; Beuthien-Baumann, B; Gommlich, A; Hofheinz, F; Jentsch, C; Krause, M; Krukowski, P; Maus, J; Mutsaerts, HJMM; Petr, J; Platzek, I; Seidlitz, A; Troost, EGC; van den Hoff, J; van Osch, MJP, 2018)
" However, a randomized controlled study (RTOG 9802) showed that adding of procarbazine, CCNU, and vincristine (PCV) chemotherapy to fractionated radiotherapy (FRT) in patients with "high-risk" WHO grade II gliomas, including DA, has significant positive impact on both progression-free survival and overall survival."3.88Chemotherapy of Diffuse Astrocytoma (WHO grade II) in Adults. ( Narita, Y, 2018)
"Resistance to temozolomide (TMZ) is a major clinical challenge in glioma treatment, but the mechanisms of TMZ resistance are poorly understood."3.88Fasudil increases temozolomide sensitivity and suppresses temozolomide-resistant glioma growth via inhibiting ROCK2/ABCG2. ( Ding, Y; Hu, R; Liu, X; Wang, Q; Yang, M; Zhang, X; Zhou, W, 2018)
"To retrospectively determine the safety and efficacy of combined chemotherapy with carmustine (BCNU) wafer, bevacizumab, and temozolomide plus radiotherapy in patients with newly diagnosed glioblastoma (GBM)."3.88Advantages and Disadvantages of Combined Chemotherapy with Carmustine Wafer and Bevacizumab in Patients with Newly Diagnosed Glioblastoma: A Single-Institutional Experience. ( Akiyama, Y; Enatsu, R; Kimura, Y; Mikami, T; Mikuni, N; Wanibuchi, M, 2018)
"The incidence, risk factors, and outcomes of low-grade glioma patients who undergo malignant transformation (MT) in the era of temozolomide are not well known."3.88Risk Factors for Malignant Transformation of Low-Grade Glioma. ( Ahluwalia, MS; Barnett, GH; Chao, ST; Jia, X; Kotecha, R; Leyrer, CM; Murphy, ES; Parsons, M; Peereboom, DM; Prayson, RA; Stevens, GHJ; Suh, JH; Vogelbaum, MA; Yu, JS, 2018)
"We collected paraffin blocks from resection specimens from 114 glioblastoma patients who had received temozolomide treatment and radiotherapy."3.88Upregulation of miR-125b, miR-181d, and miR-221 Predicts Poor Prognosis in MGMT Promoter-Unmethylated Glioblastoma Patients. ( Chen, YY; Ho, HL; Ho, TD; Hsu, CY; Lin, SC, 2018)
"A standard post-concomitant radiochemotherapy involving adjuvant temozolomide (TMZ) was stopped after 6 cycles for high-grade gliomas (HGG)."3.88Tumor Volume Changes During and After Temozolomide Treatment for Newly Diagnosed Higher-Grade Glioma (III and IV). ( Ho, JT; Ho, RW; Lin, WC; Lin, YJ; Lin, YT; Lu, CH; Tsai, NW; Wang, HC, 2018)
" This phenomenon, which has deleterious outcomes for the patient, has long been observed in patients with glioblastoma receiving temozolomide (TMZ)-based radiochemotherapy."3.88Characterizing the molecular mechanisms of acquired temozolomide resistance in the U251 glioblastoma cell line by protein microarray. ( Cui, Y; Feng, H; He, H; Li, J; Li, S; Lin, J; Qiu, G; Song, C; Wei, W; Wu, X; Xu, Q; Zuo, J, 2018)
"Previous studies showed Demethoxycurcumin (DMC) has stronger anti-glioma and anti-GSCs effects both in vitro and in vivo."3.88DMC is not better than TMZ on intracranial anti-glioma effects. ( Shi, L; Sun, G, 2018)
"Multi-institutional data from 159 patients with newly diagnosed glioblastoma who received adjuvant temozolomide concomitant chemoradiotherapy (CCRT) were collected."3.88A Comparative Analysis of the Usefulness of Survival Prediction Models for Patients with Glioblastoma in the Temozolomide Era: The Importance of Methylguanine Methyltransferase Promoter Methylation, Extent of Resection, and Subventricular Zone Location. ( Chan, D; Chan, KY; Ho, J; Lam, S; Lee, M; Ma, E; Mak, C; Poon, WS; Wong, ST; Wong, WK; Woo, P, 2018)
"To evaluate the prognostic value of the Glasgow Prognostic Score (GPS), the combination of C-reactive protein (CRP) and albumin, in glioblastoma multiforme (GBM) patients treated with radiotherapy (RT) and concurrent plus adjuvant temozolomide (GPS)."3.88Prognostic value of the Glasgow Prognostic Score for glioblastoma multiforme patients treated with radiotherapy and temozolomide. ( Ciner, F; Guler, OC; Mertsoylu, H; Ozdemir, Y; Selek, U; Topkan, E; Tufan, K; Yildirim, BA, 2018)
"To identify patients with recurrent glioblastoma after temozolomide (TMZ) concurrent with and adjuvant to radiotherapy who could benefit from TMZ rechallenge at the time of disease progression."3.88Temozolomide rechallenge in recurrent glioblastoma: when is it useful? ( Bartolini, S; Brandes, AA; Cubeddu, A; De Biase, D; Di Battista, M; Franceschi, E; Lamberti, G; Minichillo, S; Mura, A; Paccapelo, A; Pession, A; Tallini, G; Tosoni, A; Visani, M, 2018)
"Temozolomide (TMZ) is the most frequent adjuvant chemotherapy drug in gliomas."3.88Temozolomide combined with PD-1 Antibody therapy for mouse orthotopic glioma model. ( Dai, B; Li, J; Qi, N; Zhang, G, 2018)
"To investigate the clinical efficacy of stereotactic radiation therapy combined with temozolomide on recurrent glioma."3.88[Clinical efficacy of stereotactic radiation therapy combined with temozolomide on recurrent brain glioma]. ( Jiang, C; Li, X; Liu, S; Tang, S; Zhao, H, 2018)
"Human glioblastoma U251 and T98 cells and normal astrocytes C8D1A were loaded with coenzyme Q10 (CoQ)."3.88Regulation of the oxidative balance with coenzyme Q10 sensitizes human glioblastoma cells to radiation and temozolomide. ( Alcaín, FJ; Ariza, J; Arjona-Gutiérrez, J; De la Mata, M; Durán-Prado, M; Ferrín, G; Frontiñán-Rubio, J; Gil-Agudo, A; Gómez, MV; Lozano, E; Martínez-González, A; Moreno, M; Nieva-Velasco, CM; Peinado, JR; Pérez-García, VM; Pérez-Romasanta, L; Pesic, M; Santiago-Mora, RM; Villalba, JM, 2018)
"We describe the first case of a novel treatment for a newly diagnosed glioblastoma (GBM) using superselective intraarterial cerebral infusion (SIACI) of cetuximab after osmotic disruption of the blood-brain barrier (BBB) with mannitol."3.88Superselective intraarterial cerebral infusion of cetuximab with blood brain barrier disruption combined with Stupp Protocol for newly diagnosed glioblastoma. ( Alter, RA; Boockvar, JA; Chakraborty, S; Demopoulos, A; Filippi, CG; Fralin, S; Kulason, KO; Langer, DJ; Ortiz, R; Pramanik, B; Ray, A; Schneider, JR; Tan, K; Wong, T, 2018)
"We retrospectively analyzed the safety and efficacy of hypofractionated radiotherapy (45 Gy/15 fr) combined with temozolomide (TMZ) followed by bevacizumab (BEV) salvage treatment in 18 glioblastoma patients aged > 75 years."3.88Treatment outcomes of hypofractionated radiotherapy combined with temozolomide followed by bevacizumab salvage therapy in glioblastoma patients aged > 75 years. ( Kayama, T; Matsuda, KI; Nemoto, K; Sakurada, K; Sonoda, Y, 2018)
"Temozolomide (TMZ) is currently the first-line drug used for clinical postoperative or non-surgical chemotherapy for glioma, but acquired and intrinsic resistance to TMZ limits its application."3.88Synergistic Anticancer Effects of Formononetin and Temozolomide on Glioma C6 Cells. ( Fan, H; Li, Y; Ni, Q; Wang, Y; Zhang, X, 2018)
"Temozolomide (TMZ) is the preferred chemotherapeutic drug approved for the Glioblastoma multiforme (GBM) treatment."3.88miR-1268a regulates ABCC1 expression to mediate temozolomide resistance in glioblastoma. ( Deng, S; Guo, M; Li, Y; Liu, Y; Peng, Y; Qi, S; Ren, J; Shu, S; Yi, G; Zhao, L, 2018)
"Recently, D,L-methadone has been put forward as adjuvant treatment in glioblastoma (GBM)."3.88Efficacy of D,L-methadone in the treatment of glioblastoma in vitro. ( Brawanski, A; Brawanski, K; Brockhoff, G; Freyschlag, C; Hau, P; Lohmeier, A; Proescholdt, MA; Riemenschneider, MJ; Thomé, C; Vollmann-Zwerenz, A, 2018)
"Temozolomide (TMZ) is the current first-line chemotherapy for treatment of glioblastoma multiforme (GBM)."3.88Brain Targeting by Liposome-Biomolecular Corona Boosts Anticancer Efficacy of Temozolomide in Glioblastoma Cells. ( Arcella, A; Capriotti, AL; Caracciolo, G; Digiacomo, L; Frati, L; Mahmoudi, M; Oliva, MA; Palchetti, S; Pozzi, D; Rota, R; Screpanti, I; Tsaouli, G, 2018)
"We assessed survival associations of anticoagulant use from baseline up to the start of temozolomide chemoradiotherapy (TMZ/RT) (period I) and from there to the start of maintenance TMZ chemotherapy (period II) by pooling data of three randomised clinical trials in newly diagnosed glioblastoma including 1273 patients."3.88Associations of anticoagulant use with outcome in newly diagnosed glioblastoma. ( Chinot, OL; Cloughesy, T; Genbrugge, E; Gorlia, T; Le Rhun, E; Nabors, LB; Reardon, DA; Stupp, R; Weller, M; Wick, W, 2018)
" Multidrug resistance, particularly resistance to temozolomide (TMZ), is a challenge in combating glioma, and more effective therapies are needed."3.88Newcastle disease virus enhances the growth-inhibiting and proapoptotic effects of temozolomide on glioblastoma cells in vitro and in vivo. ( Bai, Y; Chen, Y; Dong, X; Hong, X; Li, S; Li, Y; Liu, X; Su, X; Zhao, G, 2018)
" For example, temozolomide (TMZ), of use for glioblastoma (GBM) treatment, appears as capable of inducing autophagy partially inhibiting cancer cell proliferation."3.88Inhibition of autophagy increases susceptibility of glioblastoma stem cells to temozolomide by igniting ferroptosis. ( Ascione, B; Buccarelli, M; D'Alessandris, QG; De Pascalis, I; Larocca, LM; Malorni, W; Marconi, M; Martini, M; Matarrese, P; Pacioni, S; Pallini, R; Ricci-Vitiani, L, 2018)
"Chemoresistance blunts the effect of Temozolomide (TMZ) in the treatment of glioblastoma multiforme (GBM)."3.88Exosomal transfer of miR-151a enhances chemosensitivity to temozolomide in drug-resistant glioblastoma. ( Huang, X; Li, R; Shen, F; Wang, X; Wei, Z; Wu, W; Yan, W; Yin, J; You, Y; Zeng, A; Zhou, X, 2018)
"In this study, we aimed to evaluate the expression and functions of MAPK8 in temozolomide (TMZ) -resistant glioblastoma cells as well as to explore the mechanism of TMZ resistance in glioblastoma cells."3.88MAPK8 mediates resistance to temozolomide and apoptosis of glioblastoma cells through MAPK signaling pathway. ( Hou, S; Sha, LG; Xu, P; Zhang, G, 2018)
"To estimate the mean lifetime survival benefit, an essential component of health economic evaluations in oncology, of adding tumor treating fields (TTFields) to maintenance temozolomide (TMZ) for newly diagnosed glioblastoma patients."3.88Estimated lifetime survival benefit of tumor treating fields and temozolomide for newly diagnosed glioblastoma patients. ( Guzauskas, GF; Salzberg, M; Wang, BC, 2018)
"A novel molecular recursive partitioning analysis classification has recently been reported integrating the MGMT promoter methylation (MGMTmeth) and IDH1 mutation (IDH1mut) status for glioblastoma (GBM-molRPA) patients treated with temozolomide-based chemoradiation."3.88Validation of a novel molecular RPA classification in glioblastoma (GBM-molRPA) treated with chemoradiation: A multi-institutional collaborative study. ( Aoki, K; Chang, JH; Cho, O; Cho, WK; Choi, JW; Chung, WK; Dho, YS; Kim, CY; Kim, E; Kim, IA; Kim, IH; Kim, JW; Kim, N; Kim, SH; Lim, DH; Motomura, K; Nam, DH; Natsume, A; Oh, YT; Ohka, F; Park, CK; Suh, CO; Wee, CW, 2018)
"Discriminating between tumor recurrence and treatment effects in glioblastoma patients undergoing radiation-temozolomide (RT/TMZ) therapy remains a major clinical challenge."3.88Diagnostic utility of restriction spectrum imaging (RSI) in glioblastoma patients after concurrent radiation-temozolomide treatment: A pilot study. ( Bartsch, H; Chen, CC; Dale, AM; Farid, N; Khan, UA; Rennert, RC; White, NS, 2018)
"Radiotherapy with procarbazine, lomustine, and vincristine (PCV) improves overall survival in patients with anaplastic oligodendroglioma 1p19q codeleted."3.88Radiotherapy plus temozolomide or PCV in patients with anaplastic oligodendroglioma 1p19q codeleted. ( Castro-Martinez, E; Gonzalez-Aguilar, A; Guerrero-Juarez, V; Gutierrez-Aceves, A; Hernandez-Hernandez, A; Lopez-Martinez, M; Peiro-Osuna, RP; Reyes-Moreno, I; Santos-Zambrano, J, 2018)
"A series of polymer-drug conjugates based on 2-methacryloyloxyethyl phosphorylcholine (MPC) was prepared with the glioblastoma drug temozolomide (TMZ) as pendent groups."3.88Polymer-Temozolomide Conjugates as Therapeutics for Treating Glioblastoma. ( Emrick, T; Saha, B; Skinner, M; Ward, SM, 2018)
"The survival rate in high-grade glioma (HGG) patients receiving a combined regimen of radiotherapy (RT) and temozolomide after tumor resection was increased."3.88A prospective longitudinal evaluation of cognition and depression in postoperative patients with high-grade glioma following radiotherapy and chemotherapy. ( Chang, J; Di, J; Lu, X; Qi, F; Song, X; Wang, Q; Yu, Y; Zhang, L; Zhou, Y, 2018)
"The efficacy of temozolomide (TMZ) chemotherapy for treating newly diagnosed glioblastoma (GBM), a primary brain tumor with short survival, was demonstrated in a clinical trial in 2005, and since then, the standard-of-care for newly diagnosed GBM has been maximal safe surgery followed by 60 Gray of radiation with concomitant and adjuvant TMZ (standard radiotherapy and TMZ)."3.88Glioblastoma Treatment with Temozolomide and Bevacizumab and Overall Survival in a Rural Tertiary Healthcare Practice. ( Carter, TC; Lawler, BE; Medina-Flores, R, 2018)
" The aim of the present study was to investigate the effect of temozolomide and thymoquinone combination on apoptotic pathway of human glioblastoma multiforme cell line (U87MG)."3.85Temozolomide-Mediated Apoptotic Death Is Improved by Thymoquinone in U87MG Cell Line. ( Khazaei, M; Pazhouhi, M, 2017)
"Radiation with concurrent and adjuvant (6 cycles) temozolomide (TMZ) is the established standard of postsurgical care for newly diagnosed glioblastoma (GBM)."3.85Is more better? The impact of extended adjuvant temozolomide in newly diagnosed glioblastoma: a secondary analysis of EORTC and NRG Oncology/RTOG. ( Baumert, BG; Blumenthal, DT; Brown, PD; Burt Nabors, L; Corn, BW; Erridge, SC; Gilbert, MR; Golfinopoulos, V; Gorlia, T; Hegi, ME; Hyun Nam, D; Kim, MM; Mason, WP; Mehta, MP; Mirimanoff, RO; Perry, JR; Reardon, DA; Stupp, R; van den Bent, MJ; Weller, M; Zhang, P, 2017)
"To determine if there is an association between the incidental radiation dose to the subventricular zone and survival in patients with glioblastoma multiforme treated with surgery, radiotherapy and temozolomide."3.85Influence of incidental radiation dose in the subventricular zone on survival in patients with glioblastoma multiforme treated with surgery, radiotherapy, and temozolomide. ( Algara, M; Foro Arnalot, P; Granados, R; Membrive, I; Ortiz, A; Pera, O; Reig, A; Rodriguez, N; Sanz, X, 2017)
"To compare various pro-apoptotic effects of synthetic 4-thiazolidinone derivative (Les-3288), doxorubicin (Dox) and temozolomide (TMZ) in the treatment of human glioma U251 cells to improve treatment outcomes of glioblastoma and avoid anticancer drug resistance."3.85Differential pro-apoptotic effects of synthetic 4-thiazolidinone derivative Les-3288, doxorubicin and temozolomide in human glioma U251 cells. ( Finiuk, N; Grytsyna, II; Klyuchivska, OY; Lehka, L; Lesyk, RB; Panchuk, RR; Starykovych, MO; Stoika, RS; Zіmenkovsky, BS; Коbylinska, LI, 2017)
"Numerous studies have reported that glioma patients with isocitrate dehydrogenase 1(IDH1) R132H mutation are sensitive to temozolomide treatment."3.85IDH1 R132H mutation regulates glioma chemosensitivity through Nrf2 pathway. ( Cai, W; He, M; Li, K; Liu, A; Luo, M; Ouyang, L; Pi, R; Tu, Y, 2017)
"In glioblastoma several histone demethylase genes (KDM) are overexpressed compared to normal brain tissue and the development of Temozolomide (TMZ) resistance is accompanied by the transient further increased expression of KDM5A and other KDMs following a mechanism that we defined as "epigenetic resilience"."3.85Small molecules targeting histone demethylase genes (KDMs) inhibit growth of temozolomide-resistant glioblastoma cells. ( Allemanni, G; Banelli, B; Daga, A; Forlani, A; Marubbi, D; Pistillo, MP; Profumo, A; Romani, M, 2017)
"Glioblastoma multiforme (GBM) exhibits high resistance to the standard treatment of temozolomide (TMZ) combined with radiotherapy, due to its remarkable cell heterogeneity."3.85Comparative analysis of the effects of a sphingosine kinase inhibitor to temozolomide and radiation treatment on glioblastoma cell lines. ( Abdollahi, A; Dokic, I; Klein, C; Oancea-Castillo, LR; Régnier-Vigouroux, A; Weber, KJ, 2017)
"Temozolomide (TMZ) is a promising chemotherapeutic agent to treat Glioblastoma multiforme (GBM)."3.85MiR-181b modulates chemosensitivity of glioblastoma multiforme cells to temozolomide by targeting the epidermal growth factor receptor. ( Chen, Y; Li, R; Liu, N; Pan, M; Shi, Z; Wang, X; Yan, W; You, Y; Zhang, J, 2017)
"Resistance to temozolomide (TMZ) chemotherapy poses a significant challenge in the treatment of glioblastoma (GBM)."3.85Defining optimal cutoff value of MGMT promoter methylation by ROC analysis for clinical setting in glioblastoma patients. ( Dai, J; Ma, K; Niu, L; Pan, Y; Wang, X; Yin, H; Yuan, G; Zhang, Y; Zhou, W, 2017)
" For these reasons, the anti-glioblastoma drug temozolomide was tested in vitro for activity against bloodstream forms of T."3.85Front-line glioblastoma chemotherapeutic temozolomide is toxic to Trypanosoma brucei and potently enhances melarsoprol and eflornithine. ( Rushworth, SA; Steverding, D, 2017)
"Temozolomide (TMZ) chemotherapy, in combination with maximal safe resection and radiotherapy, is the current standard of care for patients with glioblastoma (GBM)."3.85Therapeutic targeting of chemoresistant and recurrent glioblastoma stem cells with a proapoptotic variant of oncolytic herpes simplex virus. ( Jahan, N; Lee, JM; Shah, K; Wakimoto, H, 2017)
"Mean CBF1 expression is significantly increased in isocitrate dehydrogenase 1 (IDH1) R132H mutant glioblastoma and serves as prognostic marker for prolonged overall survival in brain tumours, particularly after therapy with temozolomide."3.85CBF1 is clinically prognostic and serves as a target to block cellular invasion and chemoresistance of EMT-like glioblastoma cells. ( Herrera-Rios, D; Hoerbelt, T; Jiang, T; Kahlert, UD; Koch, K; Li, G; Maciaczyk, D; Maciaczyk, J; Marquardt, V; Ouwens, DM; Pauck, D; Picard, D; Remke, M; Steiger, HJ; Zhang, W; Zhao, L, 2017)
"Limited benefits and clinical utility of temozolomide (TMZ) for glioblastoma (GB) are frequently compromised by the development of acquired drug resistance."3.85Connective tissue growth factor promotes temozolomide resistance in glioblastoma through TGF-β1-dependent activation of Smad/ERK signaling. ( Fu, Z; Guo, H; Lian, C; Liu, B; Xu, N; Yang, Z; Zeng, H, 2017)
" In the present study, whether MALAT1 contributes to the resistance of glioblastoma cell lines to temozolomide (TMZ) was investigated."3.85Long Non-Coding RNA MALAT1 Decreases the Sensitivity of Resistant Glioblastoma Cell Lines to Temozolomide. ( Dong, Y; Guan, F; Li, D; Li, H; Liu, X; Wang, H; Yan, D; Yang, B; Yuan, X, 2017)
"The present study analyzed outcomes of surgery followed by concomitant chemoradiotherapy (CCRT) with temozolomide (TMZ) in patients with newly diagnosed glioblastoma (GBM) at a single institution."3.85Long-term outcomes of concomitant chemoradiotherapy with temozolomide for newly diagnosed glioblastoma patients: A single-center analysis. ( Ahn, SS; Chang, JH; Cho, J; Choi, HJ; Hong, CK; Kang, SG; Kim, DS; Kim, EH; Kim, SH; Lee, KS; Lee, SK; Moon, JH; Park, HH; Roh, TH; Suh, CO, 2017)
"Recent experimental data showed that the PI3K pathway contributes to resistance to temozolomide (TMZ) in paediatric glioblastoma and that this effect is reversed by combination treatment of TMZ with a PI3K inhibitor."3.85In vitro nuclear magnetic resonance spectroscopy metabolic biomarkers for the combination of temozolomide with PI3K inhibition in paediatric glioblastoma cells. ( Agliano, A; Al-Saffar, NMS; Balarajah, G; Clarke, PA; Jackson, LE; Jones, C; Leach, MO; Marshall, LV; Pearson, ADJ; Sidhu, J; Workman, P, 2017)
"Temozolomide (TMZ) is used to treat adult patients with glioblastoma multiforme (GBM)."3.85Risk of severe acute liver injury among patients with brain cancer treated with temozolomide: a nested case-control study using the healthcore integrated research database. ( Deitz, AC; Desai, VCA; He, J; Holick, CN; Lanes, S; Quinlan, SC, 2017)
"Assessment of perfusion in early post-treatment MR imaging can stratify TTP in patients with glioblastoma for adjuvant temozolomide therapy."3.85Perfusion of surgical cavity wall enhancement in early post-treatment MR imaging may stratify the time-to-progression in glioblastoma. ( Choi, CG; Jung, SC; Kim, HS; Kim, HW; Kim, JH; Kim, SJ; Park, JE; Ryu, KH; Shim, WH, 2017)
"In this reported case, a 64-year-old woman with right temporo-parietal glioblastoma IDH-WT was treated with nivolumab, temozolomide and radiation therapy on a clinical trial."3.85Successful use of equine anti-thymocyte globulin (ATGAM) for fulminant myocarditis secondary to nivolumab therapy. ( Bergin, P; Blackley, E; Gill, S; Haydon, A; McLean, C; Moore, M; Tay, RY, 2017)
"Temozolomide is the first chemotherapeutic agent proven effective for patients with newly diagnosed glioblastoma."3.85Feasibility and safety of extended adjuvant temozolomide beyond six cycles for patients with glioblastoma. ( Chan, DT; Hsieh, SY; Kam, MK; Loong, HH; Ng, SC; Poon, DM; Poon, WS; Tsang, WK, 2017)
"Acquisition of temozolomide (TMZ) resistance is a major factor leading to the failure of glioblastoma (GBM) treatment."3.85Specificity protein 1-modulated superoxide dismutase 2 enhances temozolomide resistance in glioblastoma, which is independent of O ( Chang, KY; Chang, WC; Chen, KY; Chou, SW; Chuang, CK; Chuang, JY; Hsu, CC; Hsu, TI; Hung, JJ; Kao, TJ; Ko, CY; Liou, JP; Liu, JJ; Liu, MS; Tsai, SY, 2017)
"Temozolomide (TMZ) is the main chemotherapeutic agent used for treating newly diagnosed Glioblastoma Multiforme (GBM), the most frequent malignant brain tumors in adults."3.85HB-EGF is associated with DNA damage and Mcl-1 turnover in human glioma cell lines treated by Temozolomide. ( Gratas, C; Oliver, L; Rabé, M; Séry, Q; Vallette, FM, 2017)
"To assess the efficacy and cost-effectiveness of modulated electrohyperthermia (mEHT) concurrent to dose-dense temozolomide (ddTMZ) 21/28 days regimen versus ddTMZ 21/28 days alone in patients with recurrent glioblastoma (GBM)."3.85Clinical and economic evaluation of modulated electrohyperthermia concurrent to dose-dense temozolomide 21/28 days regimen in the treatment of recurrent glioblastoma: a retrospective analysis of a two-centre German cohort trial with systematic comparison ( Roussakow, SV, 2017)
" Standard of care for glioblastoma (GBM) includes temozolomide chemotherapy, which is not curative, due, in part, to residual therapy-resistant brain tumor-initiating cells (BTICs)."3.85Addition of carbonic anhydrase 9 inhibitor SLC-0111 to temozolomide treatment delays glioblastoma growth in vivo. ( Audia, A; Bar, EE; Benavides, GA; Bevensee, MO; Bhat, KP; Boyd, NH; Cooper, SJ; Darley-Usmar, V; Dedhar, S; Fried, J; Gillespie, GY; Gordon, E; Griguer, C; Hackney, JR; Hjelmeland, AB; Landis, CJ; McDonald, PC; Nabors, B; Nozell, S; Scott, SE; Spina, R; Tran, AN; Walker, K; Xu, B, 2017)
"It is controversial whether concurrent chemoradiotherapy (CRT) with temozolomide is feasible and beneficial in elderly patients with glioblastoma."3.85A Model to Predict the Feasibility of Concurrent Chemoradiotherapy With Temozolomide in Glioblastoma Multiforme Patients Over Age 65. ( Fietkau, R; Knippen, S; Lahmer, G; Putz, F; Semrau, S, 2017)
" However, vital safety and efficacy issues related to combined therapy with temozolomide, the first-line cytostatic in patients diagnosed with glioblastoma multiforme, and antidepressant drugs have yet to be addressed."3.85Antidepressant drugs can modify cytotoxic action of temozolomide. ( Bielecka, AM; Obuchowicz, E, 2017)
" The triazene Temozolomide (TMZ), an alkylating drug, is the classical chemotherapeutic agent for gliomas, but has been disappointing against the highly invasive and resistant nature of GBM."3.85Targeting Gliomas: Can a New Alkylating Hybrid Compound Make a Difference? ( Braga, C; Brites, D; Bronze, MR; Falcão, AS; Moreira, R; Perry, MJ; Pinheiro, R; Santos, G, 2017)
"The current standard treatment protocol for patients with newly diagnosed glioblastoma (GBM) includes surgery, radiotherapy, and concomitant and adjuvant temozolomide (TMZ)."3.85Permeability Surface Area Product Using Perfusion Computed Tomography Is a Valuable Prognostic Factor in Glioblastomas Treated with Radiotherapy Plus Concomitant and Adjuvant Temozolomide. ( Ikawa, F; Ishifuro, M; Kawamata, T; Kurisu, K; Muragaki, Y; Nishibuchi, I; Nosaka, R; Saito, T; Sugiyama, K; Takayasu, T; Yamasaki, F, 2017)
"It is unknown whether the addition of temozolomide (TMZ) to radiotherapy (RT) is associated with improved overall survival (OS) among older glioblastoma patients."3.85Comparative effectiveness of radiotherapy with vs. without temozolomide in older patients with glioblastoma. ( Arvold, ND; Cefalu, M; Dominici, F; Schrag, D; Wang, Y; Zigler, C, 2017)
" This model, developed using FM-HCR and drug sensitivity measurements in 24 human lymphoblastoid cell lines, was applied to a panel of 12 patient-derived xenograft (PDX) models of glioblastoma to predict glioblastoma response to treatment with the chemotherapeutic DNA-damaging agent temozolomide."3.85DNA Repair Capacity in Multiple Pathways Predicts Chemoresistance in Glioblastoma Multiforme. ( Chaim, IA; Gupta, SK; Joughin, BA; Kitange, GJ; Lauffenburger, DA; Mazzucato, P; Nagel, ZD; Samson, LD; Sarkaria, JN, 2017)
" In this study, we investigated the effect of silver nanoparticles (AgNPs) on human glioma U251 cells and its role in the combinational use with Temozolomide (TMZ), an imidazotetrazine derivative of the alkylating agent dacarbazine, against glioma cells."3.85Silver nanoparticles enhance the sensitivity of temozolomide on human glioma cells. ( Chen, H; Gong, Z; Gui, Q; Guo, X; Liang, P; Meng, J; Shi, H; Xu, Y; Zhu, W, 2017)
" We previously reported the immunomodulatory effects of radiation and temozolomide (TMZ) in newly diagnosed glioblastoma."3.85Immune modulation associated with vascular endothelial growth factor (VEGF) blockade in patients with glioblastoma. ( Christensen, BC; Davis, MC; Ernstoff, MS; Fadul, CE; Fisher, JL; Gaur, AB; Hampton, TH; Lewis, LD; Rahme, GJ; Steel, SE; Thomas, AA; Tsongalis, GJ; Whipple, CA, 2017)
"Temozolomide (TMZ) is an alkylating agent used for treatment of brain neoplasms and levetiracetam (LEV) is a commonly used antiepileptic."3.85Acute liver injury induced by levetiracetam and temozolomide co-treatment. ( Abu Rmeileh, A; Benson, AA; Chen, S; Cohen, J; Daher, S; Khoury, T; Mizrahi, M; Yaari, S, 2017)
"The occurrence of an inherent or acquired resistance to temozolomide (TMZ) is a major burden for patients suffering from glioma."3.85Up-regulation of miR-497 confers resistance to temozolomide in human glioma cells by targeting mTOR/Bcl-2. ( Cai, L; Su, Z; Tu, M; Yu, Z; Zeng, B; Zheng, W; Zhu, D, 2017)
"The present study aimed to investigate whether overexpression of integrin-linked kinase (ILK) affects drug resistance to temozolomide (TMZ) in glioma cells."3.85Overexpression of ILK promotes temozolomide resistance in glioma cells. ( Bao, L; Liang, F; Wang, B; Zhang, SM; Zhang, SQ; Zhao, YS, 2017)
"Although methylguanine-DNA-methyltransferase (MGMT) plays an important role in resistance to temozolomide (TMZ) in glioma, 40% of gliomas with MGMT inactivation are still resistant to TMZ."3.85FoxM1-mediated RFC5 expression promotes temozolomide resistance. ( Du, FY; Ge, L; Gong, AH; Han, X; Jin, J; Peng, WX; Zhang, CL, 2017)
"Temozolomide-(TMZ)-based chemoradiotherapy defines the current gold standard for the treatment of newly diagnosed glioblastoma."3.85Temozolomide during radiotherapy of glioblastoma multiforme : Daily administration improves survival. ( Ballhausen, H; Belka, C; Nachbichler, SB; Niyazi, M; Schupp, G, 2017)
"Glioblastoma multiforme (GBM), the most common malignant brain tumor, is currently treated with temozolomide (TMZ), but GBM often exhibits resistance to TMZ."3.85FoxO3a induces temozolomide resistance in glioblastoma cells via the regulation of β-catenin nuclear accumulation. ( Li, L; Pei, H; Wang, H; Xia, Q; Xu, K; Zhang, Z, 2017)
"The chemotherapeutic agent temozolomide (TMZ) is widely used in the treatment of glioblastoma multiforme (GBM)."3.85Rutin increases the cytotoxicity of temozolomide in glioblastoma via autophagy inhibition. ( Cheng, YS; Ho, ASW; Kiang, KMY; Lee, D; Leung, GKK; Li, N; Poon, MW; Pu, JKS; Sun, S; Zhang, P; Zhang, X, 2017)
"To explore an association with survival of modifying the current standard of care for patients with newly diagnosed glioblastoma of surgery followed by radiotherapy plus concurrent and 6 cycles of maintenance temozolomide chemotherapy (TMZ/RT → TMZ) by extending TMZ beyond 6 cycles."3.85Limited role for extended maintenance temozolomide for newly diagnosed glioblastoma. ( Bendszus, M; Felsberg, J; Gramatzki, D; Hentschel, B; Herrlinger, U; Kickingereder, P; Loeffler, M; Pietsch, T; Reifenberger, G; Sabel, M; Schackert, G; Schlegel, U; Tonn, JC; Weller, M; Westphal, M; Wick, W, 2017)
"A novel RPA classification for glioblastoma was formulated highlighting the impact of MGMTmeth and IDH1mut in the temozolomide era."3.85Novel recursive partitioning analysis classification for newly diagnosed glioblastoma: A multi-institutional study highlighting the MGMT promoter methylation and IDH1 gene mutation status. ( Chang, JH; Choe, G; Choi, SH; Kim, CY; Kim, E; Kim, IA; Kim, IH; Kim, JH; Kim, JW; Kim, N; Kim, SH; Kim, TM; Kim, YJ; Lee, ST; Park, CK; Park, SH; Suh, CO; Wee, CW, 2017)
" Then, knockdown of hnRNP A2/B1 expression induced by RNA interference (RNAi) method was used to analyze the role of hnRNP A2/B1 in glioblastoma cell viability, adhesion, migration, invasion, and chemoresistance for temozolomide (TMZ)."3.83Effects of hnRNP A2/B1 Knockdown on Inhibition of Glioblastoma Cell Invasion, Growth and Survival. ( Chen, S; Cheng, Y; Deng, J; Liang, P; Wang, F; Xie, Z; Xu, Z; Zhai, X; Zhang, Q; Zhao, H, 2016)
"Arginine-glycine-aspartic acid peptide (RGD)-modified nanostructured lipid carriers (NLCs) were used for the delivery of temozolomide (TMZ) into the GBM to provide a new paradigm in gliomatosis cerebri treatment."3.83Novel RGD containing, temozolomide-loading nanostructured lipid carriers for glioblastoma multiforme chemotherapy. ( Du, J; Mao, G; Song, S; Zhu, X, 2016)
"Few data are available on temozolomide (TMZ) in ependymomas."3.83Temozolomide as salvage treatment for recurrent intracranial ependymomas of the adult: a retrospective study. ( Bosa, C; Cassoni, P; Fiano, V; Franchino, F; Magistrello, M; Pellerino, A; Rudà, R; Soffietti, R; Trevisan, M, 2016)
"The standard of care for patients with newly diagnosed glioblastoma (GBM) is maximal safe resection followed by adjuvant radiation therapy (RT) and temozolomide (TMZ)."3.83Timing of Adjuvant Radiotherapy in Glioblastoma Patients: A Single-Institution Experience With More Than 400 Patients. ( Bruce, JN; Cheng, SK; Chow, DS; Estrada, JP; Gartrell, R; Isaacson, SR; Jani, A; Lassman, AB; McKhann, GM; Qureshi, YH; Saad, S; Sisti, MB; Soun, JE; Ung, TH; Wang, TJ, 2016)
"Temozolomide is a standard chemotherapy agent for malignant gliomas, but the efficacy is still not satisfactory."3.83Temozolomide reverses doxorubicin resistance by inhibiting P-glycoprotein in malignant glioma cells. ( Kanamori, M; Saito, R; Shibahara, I; Sonoda, Y; Sugiyama, S; Tominaga, T; Zhang, R, 2016)
"Resistance of glioblastoma (GBM) to the front-line chemotherapeutic agent temozolomide (TMZ) continues to challenge GBM treatment efforts."3.83Connexin 43 Inhibition Sensitizes Chemoresistant Glioblastoma Cells to Temozolomide. ( Gourdie, RG; Guo, S; Jourdan, J; Kanabur, P; Lamouille, S; Murphy, SF; Osimani, AM; Pridham, KJ; Rodgers, CM; Sharma, S; Sheng, Z; Simonds, GR; Varghese, RT, 2016)
"We aimed to analyze the value of seizure reduction and radiological response as prognostic markers of survival in patients with low-grade glioma (LGG) treated with temozolomide (TMZ) chemotherapy."3.83Seizure reduction is a prognostic marker in low-grade glioma patients treated with temozolomide. ( Dirven, L; Heimans, JJ; Koekkoek, JA; Postma, TJ; Reijneveld, JC; Taphoorn, MJ; Vos, MJ, 2016)
"In the effort to find better treatments for glioblastoma we tested several currently marketed non-chemotherapy drugs for their ability to enhance the standard cytotoxic drug currently used to treat glioblastoma- temozolomide."3.83Antitumor action of temozolomide, ritonavir and aprepitant against human glioma cells. ( Coveñas, R; Kast, RE; Lladó, S; Muñoz, M; Ramiro, S; Toro, S, 2016)
"The survival benefits of patients with glioblastoma (GBM) remain unsatisfactory due to the intrinsic or acquired resistance to temozolomide (TMZ)."3.83Sulforaphane reverses chemo-resistance to temozolomide in glioblastoma cells by NF-κB-dependent pathway downregulating MGMT expression. ( Han, J; Lan, F; Wu, Q; Yang, Y; Yu, H; Yue, X, 2016)
"Resistance to temozolomide (TMZ) greatly limits chemotherapeutic effectiveness in glioblastoma (GBM)."3.83Patient-derived glioblastoma cells show significant heterogeneity in treatment responses to the inhibitor-of-apoptosis-protein antagonist birinapant. ( Boyd, AW; Byrne, AT; Day, BW; Flanagan, L; Kögel, D; Murray, DW; O'Brien, DF; Prehn, JH; Rehm, M; Salvucci, M; Stringer, BW; Tivnan, A; Zakaria, Z, 2016)
"O6-methylguanine-DNA methyltransferase (MGMT) protein expression using immunohistochemical analysis was proposed as a prognostic marker for patients with newly diagnosed glioblastoma (GBM) treated with radiation therapy with concurrent and adjuvant Temozolomide (TMZ)."3.83Immunohistochemical analysis of O6-methylguanine-DNA methyltransferase (MGMT) protein expression as prognostic marker in glioblastoma patients treated with radiation therapy with concomitant and adjuvant Temozolomide. ( El-Shorbagy, SH; Khedr, RA; Younis, SG, 2016)
"A gene drug delivery system for glioma therapy based on transferrin (Tf)-modified polyamidoamine dendrimer (PAMAM) was prepared."3.83Plasmid pORF-hTRAIL targeting to glioma using transferrin-modified polyamidoamine dendrimer. ( Gao, S; Hao, B; Hong, B; Jiang, C; Li, J, 2016)
"Management of patients with glioblastoma (GBM) often includes radiation (RT) and temozolomide (TMZ)."3.83Association between treatment-related lymphopenia and overall survival in elderly patients with newly diagnosed glioblastoma. ( Campian, JL; Gao, F; Govindan, A; Huang, J; Leong, J; Mendez, JS, 2016)
" Human glioma U87MG or LNZ308 cells overexpressing either wild-type (wt) EGFR or EGFRvIII were treated with nimotuzumab, temozolomide, or both."3.83Nimotuzumab enhances temozolomide-induced growth suppression of glioma cells expressing mutant EGFR in vivo. ( Nagane, M; Nitta, Y; Shimizu, S; Shiokawa, Y; Shishido-Hara, Y; Suzuki, K, 2016)
"To confirm the hypothesis suggested above, a combined analysis of survival association of antiepileptic drug use at the start of chemoradiotherapy with temozolomide was performed in the pooled patient cohort (n = 1,869) of four contemporary randomized clinical trials in newly diagnosed glioblastoma: AVAGlio (Avastin in Glioblastoma; NCT00943826), CENTRIC (Cilengitide, Temozolomide, and Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma and Methylated Gene Promoter Status; NCT00689221), CORE (Cilengitide, Temozolomide, and Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma and Unmethylated Gene Promoter Status; NCT00813943), and Radiation Therapy Oncology Group 0825 (NCT00884741)."3.83Does Valproic Acid or Levetiracetam Improve Survival in Glioblastoma? A Pooled Analysis of Prospective Clinical Trials in Newly Diagnosed Glioblastoma. ( Chinot, O; Cloughesy, T; Gilbert, MR; Gorlia, T; Happold, C; Hegi, M; Mehta, MP; Nabors, LB; Perry, JR; Pugh, SL; Reardon, DA; Roth, P; Stupp, R; Weller, M; Wick, W, 2016)
" Triple-mutant astrocytes formed serially transplantable glioblastoma allografts that were sensitive to radiation but expressed MGMT and were resistant to temozolomide."3.83Core pathway mutations induce de-differentiation of murine astrocytes into glioblastoma stem cells that are sensitive to radiation but resistant to temozolomide. ( Bash, RE; Ewend, MG; Huey, L; McNeill, RS; Miller, CR; Schmid, RS; Simon, JM; Vitucci, M; Werneke, AM; White, KK; Wu, J, 2016)
"Methylation of the O(6)-methylguanine-DNA methyltransferase (MGMT) gene is a predictive and prognostic marker in newly diagnosed glioblastoma patients treated with temozolomide but how MGMT methylation should be assessed to ensure optimal detection accuracy is debated."3.83Assessment of Quantitative and Allelic MGMT Methylation Patterns as a Prognostic Marker in Glioblastoma. ( Aslan, D; Broholm, H; Christensen, IJ; Dyrbye, H; Grunnet, K; Grønbæk, K; Kristensen, LS; Michaelsen, SR; Poulsen, HS, 2016)
"The current standard of care for glioblastoma (GBM) is surgical resection, radiotherapy, and treatment with temozolomide (TMZ)."3.83MR Studies of Glioblastoma Models Treated with Dual PI3K/mTOR Inhibitor and Temozolomide:Metabolic Changes Are Associated with Enhanced Survival. ( Chaumeil, MM; Eriksson, P; Phillips, JJ; Radoul, M; Ronen, SM; Wang, AS, 2016)
"The role of temozolomide concurrent with and adjuvant to radiotherapy (RT/TMZ) in elderly patients with glioblastoma (GBM) remains unclear."3.83Which elderly newly diagnosed glioblastoma patients can benefit from radiotherapy and temozolomide? A PERNO prospective study. ( Baruzzi, A; Bertolini, F; Biasini, C; Brandes, AA; Cavallo, MA; Crisi, G; Dazzi, C; Depenni, R; Ermani, M; Faedi, M; Franceschi, E; Michiara, M; Mucciarini, C; Paccapelo, A; Pasini, G; Pavesi, G; Pisanello, A; Servadei, F; Sturiale, C; Urbini, B, 2016)
" O(6)-methylguanine DNA methyltransferase (MGMT), N-methylpurine DNA glycosylase (MPG), and Rad51 are DNA damage repair proteins that mediate resistance to temozolomide in glioblastoma."3.83Endoplasmic reticulum stress-inducing drugs sensitize glioma cells to temozolomide through downregulation of MGMT, MPG, and Rad51. ( Acanda, AM; Alonso, MM; Aragón, T; Fueyo, J; Garzón, AG; Gomez-Manzano, C; Gonzalez-Huarriz, M; Idoate, MA; Jones, C; Lang, FF; Martínez-Irujo, JJ; Martínez-Velez, N; Vera, B; Xipell, E, 2016)
"The combination of radiotherapy, temozolomide and valproic acid (VPA) has shown some promise in retrospective analyses of patients with glioblastoma, although their mechanisms of action remain unknown."3.83Adaptive Immune Response to and Survival Effect of Temozolomide- and Valproic Acid-induced Autophagy in Glioblastoma. ( Bumes, E; Eyüpoglu, IY; Hau, P; Hutterer, M; Proske, J; Savaskan, NE; Seliger, C; Uhl, M; Vollmann-Zwerenz, A; Walter, L, 2016)
"Clinical guidelines for gliosarcoma (GSM) are poorly defined and GSM patients are usually treated in accordance with existing guidelines for glioblastoma (GBM), with maximal surgical resection followed by chemoradiation with temozolomide (TMZ)."3.83Radiotherapy plus concomitant temozolomide in primary gliosarcoma. ( Adeberg, S; Bernhardt, D; Debus, J; Diehl, C; Harrabi, SB; Koelsche, C; Rieken, S; Unterberg, A; von Deimling, A, 2016)
" Food and Drug Administration and EMA-approved xCT inhibitor, sulfasalazine (SAS) in gliomas."3.83Sulfasalazine impacts on ferroptotic cell death and alleviates the tumor microenvironment and glioma-induced brain edema. ( Buchfelder, M; Dörfler, A; Engelhorn, T; Eyüpoglu, IY; Fan, Z; Ghoochani, A; Klucken, J; Minakaki, G; Rauh, M; Savaskan, N; Sehm, T, 2016)
"The effects of KLF8 on glioma cell proliferation, apoptosis and chemosensitivity to temozolomide (TMZ) were analyzed by Cell Counting Kit 8 assay and flow cytometry assay."3.83KLF8 Promotes Temozolomide Resistance in Glioma Cells via β-Catenin Activation. ( Wang, E; Wu, F; Yu, G, 2016)
"HIF-1α downregulation sensitizes U251 glioma cells to the temozolomide treatment via inhibiting MGMT expression and Notch1 pathway activation."3.83Downregulation of HIF-1a sensitizes U251 glioma cells to the temozolomide (TMZ) treatment. ( Huang, GH; Li, N; Lv, SQ; Ma, ZX; Sidlauskas, K; Tang, JH; Xiang, Y; Xu, QF; Zhang, EE, 2016)
"Temozolomide (TMZ) is, in combination with radiotherapy (RT), the treatment of choice for glioblastoma multiforme."3.83Persistent bone marrow depression following short-term treatment with temozolomide. ( Brandal, P; Johannesen, TB; Tjønnfjord, GE; Vandraas, K, 2016)
"Although temozolomide (TMZ) is the most effective chemotherapy agent for glioma, chemotherapy resistance has limited its clinical use."3.83Fluoxetine synergizes with temozolomide to induce the CHOP-dependent endoplasmic reticulum stress-related apoptosis pathway in glioma cells. ( Chen, MH; Chen, W; Ma, J; Sun, LL; Wang, DC; Wang, FZ; Wang, H; Wang, XD; Yang, YR, 2016)
" Here, we report increased MAP kinase-interacting kinase (MNK)-regulated phosphorylation of translation initiation factor 4E (eIF4E) in glioma cells upon temozolomide (TMZ) treatment and in medullary thyroid carcinoma (MTC) cells in response to targeted radionuclide therapy."3.83Inhibition of MNK pathways enhances cancer cell response to chemotherapy with temozolomide and targeted radionuclide therapy. ( Behe, M; Frank, S; Grzmil, M; Hemmings, BA; Hess, D; Moncayo, G; Schibli, R; Seebacher, J, 2016)
"Twenty patients with high grade glioma relapse received a stereotactic radiation; among them two patients received temozolomide and eight patients received bevacizumab; among the latter, four received also irinotecan."3.83Patterns of relapse in patients with high grade glioma receiving combined treatments including stereotactic re-irradiation for a first relapse. ( Ahle, G; Antoni, D; Atlani, D; Chaussemy, D; Clavier, JB; Couchot, J; Gaultier, C; Haoming, QC; Jastaniah, Z; Noël, G; Schott, R; Srour, R, 2016)
" In the case of glioma, temozolomide (TMZ) is the main option for treatment, but it has limited success due to drug resistance."3.83NRF2 and glutathione are key resistance mediators to temozolomide in glioma and melanoma cells. ( Fortunato, RS; Kajitani, GS; Menck, CF; Quinet, A; Rocha, CR, 2016)
"Temozolomide (TMZ) is the most commonly used alkylating agent in glioma chemotherapy."3.83miR-29c contribute to glioma cells temozolomide sensitivity by targeting O6-methylguanine-DNA methyltransferases indirectely. ( Liao, Y; Liu, J; Liu, Q; Lv, R; Qiu, X; Wu, M; Xiao, S; Yang, Z, 2016)
"Glioblastoma has a dismal prognosis, with an average overall survival of about one year despite maximal safe resection, concomitant radiochemotherapy with temozolomide followed by adjuvant temozolomide therapy."3.83Slowing down glioblastoma progression in mice by running or the anti-malarial drug dihydroartemisinin? Induction of oxidative stress in murine glioblastoma therapy. ( Blaes, J; Dong, Z; Green, E; Hertenstein, A; Jugold, M; Lemke, D; Löw, S; Ott, M; Platten, M; Pledl, HW; Sahm, F; Steffen, AC; Weiler, M; Wick, W; Winkler, F; Zorn, M, 2016)
"Maximal safe surgical resection followed by radiotherapy with concurrent and adjuvant temozolomide significantly prolonged overall survival times and was well tolerated in elderly patients with glioblastomas."3.83Analysis of Treatment Tolerance and Factors Associated with Overall Survival in Elderly Patients with Glioblastoma. ( Gao, Z; Hao, S; Ji, N; Li, Y; Song, G; Su, Z; Wang, J; Wang, X; Xie, J; Yu, L; Zhang, C; Zhang, P, 2016)
"Genotoxic chemotherapy with temozolomide (TMZ) is a mainstay of treatment for glioblastoma (GBM); however, at best, TMZ provides only modest survival benefit to a subset of patients."3.83Predicting the cell death responsiveness and sensitization of glioma cells to TRAIL and temozolomide. ( Johnston, G; Lincoln, FA; Murphy, BM; Noonan, J; Rehm, M; Weyhenmeyer, BC; Würstle, ML, 2016)
" 1) VPA treatment clearly sensitized glioma cells to temozolomide: A protruding VPA-induced molecular feature in this context was the transcriptional upregulation/reexpression of numerous solute carrier (SLC) transporters that was also reflected by euchromatinization on the histone level and a reexpression of SLC transporters in human biopsy samples after VPA treatment."3.83Molecular dissection of the valproic acid effects on glioma cells. ( Hau, P; Herold-Mende, C; Hoja, S; Proescholdt, M; Rehli, M; Riemenschneider, MJ; Schulze, M, 2016)
"Temozolomide (TMZ) is an alkylating agent that has become the mainstay treatment of the most malignant brain cancer, glioblastoma multiforme (GBM)."3.83Zinc enhances temozolomide cytotoxicity in glioblastoma multiforme model systems. ( Assoulin, M; Constantini, S; Daniels, D; Fisher, T; Freedman, S; Guez, D; Last, D; Mardor, Y; Mehrian-Shai, R; Moshe, I; Pismenyuk, T; Reichardt, JK; Simon, AJ; Toren, A; Yalon, M, 2016)
" The purpose of this study was determining the effects of HL156A, a newly designed biguanide with improved pharmacokinetics, on glioblastoma TSs (GMB TSs) and assess the feasibility of this drug as a new line of therapy against glioblastoma, alone or combined with a conventional therapeutic agent, temozolomide(TMZ)."3.83Inhibiting stemness and invasive properties of glioblastoma tumorsphere by combined treatment with temozolomide and a newly designed biguanide (HL156A). ( Chang, JH; Cheong, JH; Choi, J; Huh, YM; Jeon, JY; Kang, SG; Kim, EH; Kim, P; Kim, SH; Koh, I; Lee, JH; Lee, SJ; Park, J; Pollak, M; Shim, JK; Yook, JI; Yun, M, 2016)
" In the OP group with GBM and anaplastic glioma, patients treated with RT combined with temozolomide (TMZ) manifested significantly longer OS and PFS compared with patients assigned to RT alone (P < 0."3.83Radiation combined with temozolomide contraindicated for young adults diagnosed with anaplastic glioma. ( Cai, J; Jiang, T; Li, S; Li, W; Peng, X; Qiu, X; Wang, Y; Wu, C; Yang, P; Yao, K; You, G; Zhang, C; Zhang, W, 2016)
"Twenty patients with recurrent glioblastoma were treated with biweekly BEV plus temozolomide."3.83MRI and 11C-methyl-L-methionine PET Differentiate Bevacizumab True Responders After Initiating Therapy for Recurrent Glioblastoma. ( Beppu, T; Kato, K; Ogasawara, K; Sasaki, M; Sasaki, T; Sato, Y; Terasaki, K; Tomabechi, M, 2016)
"Concomitant use of temozolomide (TMZ) and radiotherapy, which is the standard therapy for patients with high-grade glioma, involves a unique regimen with multiple-day, long-term administration."3.83Combination of Palonosetron, Aprepitant, and Dexamethasone Effectively Controls Chemotherapy-induced Nausea and Vomiting in Patients Treated with Concomitant Temozolomide and Radiotherapy: Results of a Prospective Study. ( Akutsu, H; Ishikawa, E; Matsuda, M; Matsumura, A; Takano, S; Yamamoto, T, 2016)
"It has been reported that metformin acts synergistically with temozolomide (TMZ) to inhibit proliferation of glioma cells including glioblastoma multiforme (GBM)."3.83Metformin treatment reduces temozolomide resistance of glioblastoma cells. ( Kim, DH; Li, S; Liu, Y; Lu, G; Xue, H; Yang, SH; Zhu, JJ, 2016)
"To analyze the enhancement patterns and apparent diffusion coefficient (ADC) values of non-measurable surgical cavity wall enhancement pattern, newly appearing after completion of standard concurrent chemoradiotherapy (CCRT) with temozolomide in glioblastoma patients for the prognosis prediction."3.83MR Imaging Analysis of Non-Measurable Enhancing Lesions Newly Appearing after Concomitant Chemoradiotherapy in Glioblastoma Patients for Prognosis Prediction. ( Choi, SH; Kim, BR; Kim, IH; Kim, JH; Kim, TM; Lee, ST; Park, CK; Park, SH; Park, SW; Sohn, CH; Yun, TJ, 2016)
"Temozolomide (TMZ), an alkylating agent of the imidazotetrazine series, is a first-line chemotherapeutic drug used in the clinical therapy of glioblastoma multiforme, the most common and high-grade primary glioma in adults."3.83The Inhibition of microRNA-128 on IGF-1-Activating mTOR Signaling Involves in Temozolomide-Induced Glioma Cell Apoptotic Death. ( Chang, CK; Chen, KC; Chen, PH; Cheng, CH; Ho, KH; Lee, CC; Lin, CW; Liu, AJ; Shih, CM, 2016)
"The aim of this study was to investigate the effect of downregulating Hedgehog pathway by GANT61 on human glioma cells, examine the consequent changes of temozolomide (TMZ)-induced effects and explore the molecular mechanisms."3.83GANT61, a GLI inhibitor, sensitizes glioma cells to the temozolomide treatment. ( Cai, J; Chen, L; Jiang, C; Li, J; Li, R; Li, Y; Sun, Y; Yao, K; Zhai, X; Zhang, J; Zhao, S, 2016)
"Epidermal growth factor receptor (EGFR)vIII is the most common EGFR mutant found in glioblastoma (GBM)."3.81EGFR wild type antagonizes EGFRvIII-mediated activation of Met in glioblastoma. ( Boothman, DA; Burma, S; Chakraborty, S; Habib, AA; Hatanpaa, KJ; Koduru, P; Li, L; Puliyappadamba, VT; Rehman, A; Saha, D; Souza, RF; Vemireddy, V, 2015)
"Twenty-two newly diagnosed patients with primary malignant gliomas underwent 6 weeks of combined modality treatment (CMD) with radiation and temozolomide followed by six monthly cycles of temozolomide."3.81Analysis of salivary fluid and chemosensory functions in patients treated for primary malignant brain tumors. ( Case, D; Dietrich, AM; Duncan, SE; Harmon, M; Lesser, G; Mirlohi, S, 2015)
"Concurrent chemoradiotherapy with temozolomide, the current standard treatment after surgery for glioblastoma, could be shortened without increasing side effects for patients with poor prognostic features."3.81Hypofractionated chemoradiotherapy with temozolomide as a treatment option for glioblastoma patients with poor prognostic features. ( Choi, SH; Han, TJ; Kim, IH; Kim, TM; Lee, SH; Lim, YJ; Paek, SH; Park, CK; Park, SH, 2015)
"To explore the role of dynamic contrast material-enhanced magnetic resonance (MR) imaging in the differentiation of true progression from pseudoprogression in patients with glioblastoma on the basis of findings in entirely newly developed or enlarged enhancing lesions after concurrent radiation therapy and chemotherapy with temozolomide and to evaluate the diagnostic performance of the quantitative pharmacokinetic parameters obtained at dynamic contrast-enhanced MR imaging, such as the volume transfer constant (K(trans)), the extravascular extracellular space per unit volume of tissue(ve), and the blood plasma volume per unit volume of tissue(vp)."3.81Glioblastoma treated with concurrent radiation therapy and temozolomide chemotherapy: differentiation of true progression from pseudoprogression with quantitative dynamic contrast-enhanced MR imaging. ( Choi, SH; Kim, IH; Kim, JH; Kim, TM; Lee, SH; Park, CK; Park, SH; Sohn, CH; Yun, TJ, 2015)
"The cellular responses to two new temozolomide (TMZ) analogues, DP68 and DP86, acting against glioblastoma multiforme (GBM) cell lines and primary culture models are reported."3.81Evaluation of novel imidazotetrazine analogues designed to overcome temozolomide resistance and glioblastoma regrowth. ( Gynther, M; Mladek, AC; Phillips, RM; Ramirez, YP; Rautio, J; Ross, AH; Sakaria, JN; Wheelhouse, RT, 2015)
"The upregulation of Livin expression and downregulation of caspase activity were observed under cycling and chronic hypoxia in glioblastoma cells and xenografts, concomitant with increased TR to ionizing radiation and temozolomide."3.81Livin contributes to tumor hypoxia-induced resistance to cytotoxic therapies in glioblastoma multiforme. ( Hsieh, CH; Lee, HT; Lin, YJ; Shyu, WC; Wang, CC; Wu, CP, 2015)
"The present in vitro study aimed to assess the effects of combining the mTOR inhibitor RAD001 and temozolomide (TMZ) together with irradiation by either low-linear energy transfer (LET) radiation (γ-rays) or high-LET radiation (fast neutrons) on the growth and cell survival of the human glioblastoma cell line U-87."3.81Combination of the mTOR inhibitor RAD001 with temozolomide and radiation effectively inhibits the growth of glioblastoma cells in culture. ( Bischoff, P; Burckel, H; Denis, JM; Gueulette, J; Josset, E; Noël, G; Slabbert, J, 2015)
"To evaluate 2 specific radiation schedules, each combined with temozolomide (TMZ), assessing their efficacy and safety in patients aged ≥65 years with newly diagnosed glioblastoma (GBM)."3.81Standard (60 Gy) or short-course (40 Gy) irradiation plus concomitant and adjuvant temozolomide for elderly patients with glioblastoma: a propensity-matched analysis. ( Arcella, A; Bozzao, A; Enrici, RM; Esposito, V; Giangaspero, F; Lanzetta, G; Minniti, G; Pace, A; Scaringi, C; Terrenato, I, 2015)
"Glioblastoma (GBM) is a highly proliferative, angiogenic grade IV astrocytoma that develops resistance to the alkylating agents used in chemotherapy, such as temozolomide (TMZ), which is considered the gold standard."3.81Tamoxifen in combination with temozolomide induce a synergistic inhibition of PKC-pan in GBM cell lines. ( Balça-Silva, J; do Carmo, A; Girão, H; Lopes, MC; Matias, D; Moura-Neto, V; Sarmento-Ribeiro, AB, 2015)
"We retrospectively identified 68 consecutive patients with high-grade gliomas treated by surgical resection followed by radiation therapy and temozolomide, who then developed increasing enhancing mass lesions indeterminate for treatment-related changes versus recurrent tumor."3.81Diffusion and perfusion MRI to differentiate treatment-related changes including pseudoprogression from recurrent tumors in high-grade gliomas with histopathologic evidence. ( Beal, K; Martinez, N; Omuro, A; Prager, AJ; Young, RJ; Zhang, Z, 2015)
"Glioblastoma Multiforme (GBM), the most common and lethal adult primary tumor of the brain, showed a link between Sonic Hedgehog (SHH) pathway in the resistance to temozolomide (TMZ)."3.81Temozolomide resistance in glioblastoma occurs by miRNA-9-targeted PTCH1, independent of sonic hedgehog level. ( Greco, SJ; Ligon, KL; Munoz, JL; Rameshwar, P; Ramkissoon, SH; Rodriguez-Cruz, V, 2015)
"The aim of this prospective longitudinal study was to identify static and dynamic O-(2-[(18)F]fluoroethyl)-L-tyrosine PET ((18)FET-PET)-derived imaging biomarkers in patients with glioblastoma (GBM)."3.81Biological tumor volume in 18FET-PET before radiochemotherapy correlates with survival in GBM. ( Eigenbrod, S; Jansen, NL; Janssen, H; Kreth, FW; Kretzschmar, H; la Fougere, C; Linn, J; Pöpperl, G; Simon, M; Suchorska, B; Tonn, JC; Weller, M, 2015)
" Chemotherapy has been observed to prolong overall survival rate and temozolomide (TMZ), a promising chemotherapeutic agent for treating glioblastoma (GBM), possesses the most effective clinical activity at present, although drug resistance limits its clinical outcome."3.81p53 upregulated modulator of apoptosis sensitizes drug-resistant U251 glioblastoma stem cells to temozolomide through enhanced apoptosis. ( Fan, Y; Guo, G; Li, Q; Lian, S; Liu, X; Miao, W; Wang, H; Wang, S; Wang, X; Yang, X, 2015)
"Temozolomide (TMZ) increases the overall survival of patients with glioblastoma (GBM), but its role in the clinical management of diffuse low-grade gliomas (LGG) is still being defined."3.81Evolution of DNA repair defects during malignant progression of low-grade gliomas after temozolomide treatment. ( Aburatani, H; Aihara, K; Berger, MS; Chang, SM; Costello, JF; Fouse, SD; Hallbeck, M; Heimans, JJ; Hong, C; Johnson, BE; Kloezeman, JJ; Lamfers, ML; Malmström, A; Mazor, T; Molinaro, AM; Mukasa, A; Reijneveld, JC; Saito, N; Söderkvist, P; Stenmark-Askmalm, M; Taylor, BS; van Thuijl, HF; Wesseling, P; Ylstra, B, 2015)
"Lack of robust predictive biomarkers, other than MGMT promoter methylation, makes temozolomide responsiveness in newly diagnosed glioblastoma (GBM) patients difficult to predict."3.81EGFR amplified and overexpressing glioblastomas and association with better response to adjuvant metronomic temozolomide. ( Bonetti, MF; Branca, C; Buglione, M; Buttolo, L; Cominelli, M; Dalerba, P; Facchetti, F; Finocchiaro, G; Furlan, D; Galli, R; Grisanti, S; Liserre, B; Liserre, R; Mazzoleni, S; Medicina, D; Pellegatta, S; Pellegrini, V; Pizzi, M; Poliani, PL, 2015)
" In this project, we evaluated the effects of silibinin, a natural plant component of milk thistle seeds, to potentiate toxic effects of chemotherapy drugs such as temozolomide, etoposide and irinotecan on LN229, U87 and A172 (P53 and phosphatase and tensin homolog (PTEN) -tumor suppressor-mutated) glioma cell lines."3.81The effect of silibinin in enhancing toxicity of temozolomide and etoposide in p53 and PTEN-mutated resistant glioma cell lines. ( Elhag, R; Mazzio, EA; Soliman, KF, 2015)
"In this study, we developed and characterized a delivery system for the epigenetic demethylating drug, decitabine, to sensitize temozolomide-resistant human glioblastoma multiforme (GBM) cells to alkylating chemotherapy."3.81Decitabine nanoconjugate sensitizes human glioblastoma cells to temozolomide. ( Cui, Y; Irudayaraj, J; Naz, A; Thompson, DH, 2015)
"Temozolomide (TMZ) is the first line drug in the care of high grade gliomas."3.81Temozolomide and radiotherapy versus radiotherapy alone in high grade gliomas: a very long term comparative study and literature review. ( Clemente, MA; Corsa, P; Cossa, S; Donno, E; Munafò, T; Parisi, F; Parisi, S; Perrone, A; Piombino, M; Raguso, A; Sanpaolo, G; Valle, G, 2015)
"Despite multimodal treatment, glioblastoma (GBM) therapy with temozolomide (TMZ) remains inefficient due to chemoresistance."3.81The metalloprotease-disintegrin ADAM8 contributes to temozolomide chemoresistance and enhanced invasiveness of human glioblastoma cells. ( Bartsch, JW; Biniossek, ML; Carl, B; Conrad, C; Culmsee, C; Dolga, AM; Dong, F; Eibach, M; Koller, G; Nimsky, C; Schieber, S; Schilling, O; Schlomann, U; Strik, H, 2015)
"High-grade gliomas, glioblastomas (GB), are refractory to conventional treatment combining surgery, chemotherapy, mainly temozolomide, and radiotherapy."3.81Metformin inhibits growth of human glioblastoma cells and enhances therapeutic response. ( Brem, H; Cohen-Jonathan Moyal, E; Dahan, P; Dang, VT; Lemarié, A; Saland, E; Sarry, JE; Scotland, SJ; Sesen, J; Skuli, N; Toulas, C; Tyler, BM, 2015)
"We examined whether the amino acid PET tracers, trans-1-amino-3-(18)F-fluorocyclobutanecarboxylic acid (anti-(18)F-FACBC) and (11)C-methyl-l-methionine ((11)C-Met), are suitable for detecting early responses to combination therapies including temozolomide (TMZ), interferon-β (IFN), and bevacizumab (Bev) in glioblastoma."3.81Amino acid PET tracers are reliable markers of treatment responses to single-agent or combination therapies including temozolomide, interferon-β, and/or bevacizumab for glioblastoma. ( Baden, A; Doi, Y; Kanagawa, M; Mizoi, K; Oka, S; Ono, M; Ono, T; Sasajima, T; Shimizu, H, 2015)
"Two independent temozolomide-treated glioblastoma cohorts-one Australian (Australian Genomics and Clinical Outcomes of Glioma, n = 163) and the other American (University of California Los Angeles/Kaiser Permanente Los Angeles, n = 159)-were studied."3.81The MGMT promoter SNP rs16906252 is a risk factor for MGMT methylation in glioblastoma and is predictive of response to temozolomide. ( Cloughesy, TF; Ha, W; Hitchins, MP; Lai, A; McDonald, KL; Nguyen, HN; Nowak, AK; Rapkins, RW; Wang, F, 2015)
"Resistance to temozolomide (TMZ) is a major obstacle in the treatment of glioblastoma multiforme (GBM)."3.81miR-20a mediates temozolomide-resistance in glioblastoma cells via negatively regulating LRIG1 expression. ( Mo, L; Qi, X; Wan, Y; Wang, Y; Wei, J; Xie, D; Xie, J; Yan, Q; Yang, S; Zhan, Q; Zhou, D, 2015)
" The objective of this study was to assess the survival benefit of LEV compared with other antiepileptic drugs as a chemosensitizer to temozolomide for patients with glioblastoma."3.81Survival benefit of levetiracetam in patients treated with concomitant chemoradiotherapy and adjuvant chemotherapy with temozolomide for glioblastoma multiforme. ( Han, JH; Joo, JD; Kim, CY; Kim, IA; Kim, T; Kim, YH; Kim, YJ; Yun, CH, 2015)
"It is currently unclear whether adjuvant therapy for WHO grade III anaplastic astrocytomas (AA) should be carried out as combined chemoradiotherapy with temozolomide (TMZ)--analogous to the approach for glioblastoma multiforme--or as radiotherapy (RT) alone."3.81Adjuvant temozolomide-based chemoradiotherapy versus radiotherapy alone in patients with WHO III astrocytoma: The Mainz experience. ( Giese, A; Mayer, A; Renovanz, M; Schmidberger, H; Schwanbeck, C; Sommer, C; Stockinger, M; Vaupel, P, 2015)
"Acute severe lymphopenia (ASL) frequently develops during radiation therapy (RT) and concurrent temozolomide (TMZ) for high-grade glioma (HGG) and is associated with decreased survival."3.81Clinical and Dosimetric Predictors of Acute Severe Lymphopenia During Radiation Therapy and Concurrent Temozolomide for High-Grade Glioma. ( Badiyan, SN; Campian, JL; Chicoine, MR; DeWees, TA; Dunn, G; Fergus, S; Huang, J; Kim, AH; Linette, G; Mullen, DF; Robinson, CG; Simpson, JR; Speirs, CK; Tran, DD, 2015)
" Cutoff values of MGMT methylation specific for metastatic colorectal cancer (mCRC) tissue samples were established in a cohort of 60 patients treated with dacarbazine."3.81Digital PCR quantification of MGMT methylation refines prediction of clinical benefit from alkylating agents in glioblastoma and metastatic colorectal cancer. ( Amatu, A; Barault, L; Bardelli, A; Bleeker, FE; Cassingena, A; Cassoni, P; De Braud, F; de Witt Hamer, P; Di Nicolantonio, F; Esteller, M; Falcomatà, C; Fiano, V; Milione, M; Moutinho, C; Pietrantonio, F; Rudà, R; Sartore-Bianchi, A; Siena, S; Siravegna, G; Soffietti, R; Venesio, T; Wesseling, P, 2015)
"The AVAglio (Avastin in Glioblastoma) and RTOG-0825 randomized, placebo-controlled phase III trials in newly diagnosed glioblastoma reported prolonged progression-free survival (PFS), but not overall survival (OS), with the addition of bevacizumab to radiotherapy plus temozolomide."3.81Patients With Proneural Glioblastoma May Derive Overall Survival Benefit From the Addition of Bevacizumab to First-Line Radiotherapy and Temozolomide: Retrospective Analysis of the AVAglio Trial. ( Abrey, LE; Bais, C; Bourgon, R; Chinot, OL; Cloughesy, T; Garcia, J; Hegde, P; Henriksson, R; Kharbanda, S; Lai, A; Li, C; Mason, W; Moore, N; Nishikawa, R; Peale, F; Phillips, HS; Sandmann, T; Saran, F; Wick, W, 2015)
" The introduction of temozolomide (TMZ) has advanced chemotherapy for malignant gliomas."3.81NVP-BEZ235, a novel dual PI3K-mTOR inhibitor displays anti-glioma activity and reduces chemoresistance to temozolomide in human glioma cells. ( Chen, Y; Cheng, Y; Li, Y; Xie, G; Yao, G; Yu, Z; Zhang, G; Zhao, G; Zhou, G, 2015)
"Temozolomide plays a critical role in curing glioma at present."3.81Liposome encapsulated of temozolomide for the treatment of glioma tumor: preparation, characterization and evaluation. ( Gao, J; Huang, G; Liu, H; Wang, L; Wang, Z, 2015)
" Glioblastoma (GBM) has poor survival rate and uniformly acquired chemoresistance to its frontline agent, Temozolomide (TMZ)."3.81Temozolomide competes for P-glycoprotein and contributes to chemoresistance in glioblastoma cells. ( Munoz, JL; Rameshwar, P; Scotto, KW; Walker, ND, 2015)
" The present study was undertaken to determine whether the cytotoxicity of curcumin (diferuloylmethane), a natural polyphenolic compound isolated from turmeric (Curcuma longa Linn), in glioblastoma cells is mediated through upregulation of miR‑146a."3.81Induction of microRNA-146a is involved in curcumin-mediated enhancement of temozolomide cytotoxicity against human glioblastoma. ( Cai, T; Chen, YD; Liu, Q; Wang, ZF; Wu, H, 2015)
" Our aim was to determine whether the subependymal enhancement pattern and ADC can differentiate true progression from pseudoprogression in patients with glioblastoma multiforme treated with concurrent chemoradiotherapy by using temozolomide."3.81Independent Poor Prognostic Factors for True Progression after Radiation Therapy and Concomitant Temozolomide in Patients with Glioblastoma: Subependymal Enhancement and Low ADC Value. ( Choi, SH; Kim, IH; Kim, JH; Kim, TM; Lee, SH; Park, CK; Park, SH; Sohn, CH; Yoo, RE; Yun, TJ, 2015)
" A 48-year-old patient had supratentorial glioblastoma, treated with radiotherapy (RT) and concurrent temozolomide followed by six cycles of adjuvant temozolomide."3.81Diagnosis and Management of Spinal Metastasis of Glioblastoma. ( Dubey, A; Koul, R; Salim, M; Tai, P; Vu, K, 2015)
"Although temozolomide (TMZ) is the current first-line chemotherapy for glioblastoma multiforme (GBM), most patients either do not respond or ultimately fail TMZ treatment."3.81Encapsulation of temozolomide in a tumor-targeting nanocomplex enhances anti-cancer efficacy and reduces toxicity in a mouse model of glioblastoma. ( Chang, EH; DeMarco, J; Kim, E; Kim, SS; Pirollo, KF; Rait, A, 2015)
" Interestingly, our findings showed an association of metformin therapy and prolonged progression-free survival in glioblastoma patients with diabetes and therefore serve as a foundation for further preclinical and clinical investigations."3.81Metformin influences progression in diabetic glioblastoma patients. ( Adeberg, S; Ben Harrabi, S; Bernhardt, D; Bostel, T; Debus, J; Diehl, C; Koelsche, C; Mohr, A; Rieken, S, 2015)
" In addition, in contrast to IDH1-mutated gliomas, IDH1-wild-type primary GBMs rarely developed hypermutation following temozolomide (TMZ) treatment, indicating low risk for TMZ-induced hypermutation for these tumors under the standard regimen."3.81Spatiotemporal Evolution of the Primary Glioblastoma Genome. ( Cho, HJ; Johnson, MD; Joo, KM; Jung, YS; Kim, BS; Kim, J; Kim, Y; Kong, DS; Lee, IH; Lee, J; Lee, JI; Nam, DH; Nam, SH; Park, CK; Park, PJ; Park, WY; Seol, HJ; Yoon, Y, 2015)
"Mesoporous silica nanoparticles (MSNPs), 100 nm in size, incorporating a Cy5 fluorophore within the silica framework, are synthesized and loaded with the anti-cancer drug temozolomide (TMZ), used in the treatment of gliomas."3.81Combined Delivery of Temozolomide and Anti-miR221 PNA Using Mesoporous Silica Nanoparticles Induces Apoptosis in Resistant Glioma Cells. ( Bertucci, A; Brognara, E; Corradini, R; De Cola, L; Gambari, R; Manicardi, A; Prasetyanto, EA; Septiadi, D, 2015)
"The efficacy of temozolomide (TMZ) plus radiation therapy (RT) in elderly patients with glioblastoma is unclear."3.81Predictors of survival and effect of short (40 Gy) or standard-course (60 Gy) irradiation plus concomitant temozolomide in elderly patients with glioblastoma: a multicenter retrospective study of AINO (Italian Association of Neuro-Oncology). ( Anghileri, E; Bazzoli, E; Bellu, L; Berti, F; D'Avella, D; Dall'Agata, M; Della Puppa, A; Eoli, M; Fabi, A; Faedi, M; Ferrazza, P; Gurrieri, L; Lombardi, G; Nicolotto, E; Pace, A; Pambuku, A; Pasqualetti, F; Rizzato, S; Rudà, R; Villani, V; Zagonel, V, 2015)
"For glioblastoma patients who underwent Temozolomide and Radiation Therapy, OS and PFS was most favorable for those with tumors harboring both mIDH and methMGMT (median OS: 35."3.81IDH mutation and MGMT promoter methylation in glioblastoma: results of a prospective registry. ( Chen, B; Chen, CC; Jiang, T; Li, G; Li, J; Li, S; Li, W; Peng, X; Qiu, X; Wang, Y; Wu, C; Yan, W; Yang, P; Yao, K; You, Y; Zhang, W, 2015)
"Our laboratory reported that Irinophore C™ (IrC™; a lipid-based nanoparticulate formulation of irinotecan) is effective against an orthotopic model of glioblastoma (GBM) and that treatment with IrC™ was associated with vascular normalization within the tumor."3.81Determination of an optimal dosing schedule for combining Irinophore C™ and temozolomide in an orthotopic model of glioblastoma. ( Anantha, M; Backstrom, I; Bally, MB; Chu, F; Kalra, J; Masin, D; Strutt, D; Verreault, M; Walker, D; Waterhouse, D; Wehbe, M; Yapp, DT, 2015)
"This study was performed to validate the effectiveness and safety of concurrent chemoradiotherapy and adjuvant therapy with temozolomide for newly diagnosed glioblastoma multiforme as a standard treatment protocol."3.81Validation of the Effectiveness and Safety of Temozolomide during and after Radiotherapy for Newly Diagnosed Glioblastomas: 10-year Experience of a Single Institution. ( Han, JH; Joo, JD; Kim, CY; Kim, H; Kim, YH, 2015)
"Glioblastoma (GBM) generally exhibits high IC50 values for its standard drug treatment, temozolomide (TMZ)."3.81Nanoparticle-Delivered Antisense MicroRNA-21 Enhances the Effects of Temozolomide on Glioblastoma Cells. ( Ananta, JS; Massoud, TF; Paulmurugan, R, 2015)
"Notwithstanding current multimodal treatment, including surgery, radiotherapy and chemotherapy with temozolomide (TMZ), median survival of glioblastoma (GBM) patients is about 14 months, due to the rapid emergence of cell clones resistant to treatment."3.81The histone demethylase KDM5A is a key factor for the resistance to temozolomide in glioblastoma. ( Allemanni, G; Banelli, B; Barbieri, F; Carosio, R; Carra, E; Daga, A; Florio, T; Forlani, A; Marubbi, D; Parodi, F; Pattarozzi, A; Romani, M; Würth, R, 2015)
" Here, we built protein interaction networks associated with chemoresistance to temozolomide, an alkylating agent used in glioma therapy, and analyzed their modular structure and robustness against intentional attack."3.81Topological robustness analysis of protein interaction networks reveals key targets for overcoming chemotherapy resistance in glioma. ( Azevedo, H; Moreira-Filho, CA, 2015)
"Glioma stem cells are associated for temozolomide-resistance in glioblastoma."3.81Co-expression of Cytoskeletal Protein Adducin 3 and CD133 in Neurospheres and a Temozolomide-resistant Subclone of Glioblastoma. ( Leung, GK; Poon, MW; Sun, S; Wong, ST; Zhang, XQ; Zhuang, JT, 2015)
"The EpiBrainRad study is a prospective cohort study including newly diagnosed high grade gliomas patients treated by radiotherapy and concomitant-adjuvant temozolomide chemotherapy."3.81EpiBrainRad: an epidemiologic study of the neurotoxicity induced by radiotherapy in high grade glioma patients. ( Benderitter, M; Bernier, MO; Brochet, B; Delattre, JY; Douzane, H; Durand, T; Feuvret, L; Hoang-Xuan, K; Jacob, S; Lebouil, L; Leclercq, D; Lestaevel, P; Milliat, F; Noël, G; Psimaras, D; Rahimian, A; Ricard, D; Tamarat, R; Vayatis, N, 2015)
"Temozolomide (TMZ) with radiotherapy is the current standard of care for newly diagnosed glioma."3.81MiR-16 modulate temozolomide resistance by regulating BCL-2 in human glioma cells. ( Chen, Q; Han, J, 2015)
"The standard adjuvant treatment for glioblastoma is temozolomide concomitant with radiotherapy, followed by a further six cycles of temozolomide."3.80Should we continue temozolomide beyond six cycles in the adjuvant treatment of glioblastoma without an evidence of clinical benefit? A cost analysis based on prescribing patterns in Spain. ( Arranz, JL; Balañá, C; Benavides, M; Bugés, C; Cano, JM; de la Peñas, R; García-Bueno, JM; Gil, M; Lopez, D; Martin, JM; Molina-Garrido, MJ; Perez-Segura, P; Rodriguez, A; Sanz, SM; Sepúlveda, JM; Vaz, MA, 2014)
"To assess effectiveness of 5-aminolevulinic acid (5-ALA, Gliolan(®)) in patients treated for malignant glioma under typical daily practice conditions in Spain, using complete resection rate (CR) and progression free survival at 6 months (PFS6)."3.80Observational, retrospective study of the effectiveness of 5-aminolevulinic acid in malignant glioma surgery in Spain (The VISIONA study). ( Arza, C; Díez Valle, R; Galván, J; Romariz, C; Slof, J; Vidal, C, 2014)
"Although temozolomide (TMZ) replaced nitrosoureas as the standard initial chemotherapy for glioblastoma (GBM), no studies have compared TMZ with nimustine (ACNU), a nitrosourea agent widely used in central Europe and most Asian regions."3.80Comparison of the clinical efficacy of temozolomide (TMZ) versus nimustine (ACNU)-based chemotherapy in newly diagnosed glioblastoma. ( Chen, B; Chen, L; Chen, X; Jiang, T; Li, S; Wang, J; Wang, L; Wang, Y; Wu, C; Zhang, X; Zhang, Z, 2014)
"The aim of this study is to investigate the inhibitory effects of 2T-P400, a derivative of temozolomide (TMZ), on glioma growth."3.80The temozolomide derivative 2T-P400 inhibits glioma growth via administration route of intravenous injection. ( Dong, J; Li, R; Tang, D; Wang, L; Wu, J; Zhang, J, 2014)
"It is now accepted that the concomitant administration of temozolomide with radiotherapy (Stupp regime), in the treatment of patients with newly diagnosed glioblastoma multiforme (GBM), significantly improves survival and this practice has been adopted locally since 2004."3.80A survival analysis of GBM patients in the West of Scotland pre- and post-introduction of the Stupp regime. ( Clark, B; Mackinnon, M; Martin, S; Nowicki, S; Owusu-Agyemang, K; Paul, J; St George, J; Stewart, W; Teo, M, 2014)
"Our purpose was to analyze the pattern of failure in glioblastoma (GBM) patients at first recurrence after radiotherapy and temozolomide and its relationship with different factors."3.80Factors associated with a higher rate of distant failure after primary treatment for glioblastoma. ( Aldave, G; de Gallego, J; Díez-Valle, R; Domínguez, PD; Gállego Pérez-Larraya, J; Marigil, M; Tejada, S, 2014)
" This study employed intracranial human glioma models to evaluate the effect of BEV alone and in combination with temozolomide (TMZ) and/or radiation therapy (XRT) on overall survival."3.80Combination of anti-VEGF therapy and temozolomide in two experimental human glioma models. ( Blakeley, JO; Brastianos, H; Brem, H; Goodwin, RC; Grossman, R; Hwang, L; Lal, B; Mangraviti, A; Tyler, B; Wicks, RT; Zadnik, P, 2014)
"Radiotherapy (RT) and temozolomide (TMZ) for glioblastoma (GBM) has resulted in longer survival."3.80Employment following chemoradiotherapy in glioblastoma: a prospective case series. ( Back, M; Guo, L; Gzell, C; Kastelan, M; Wheeler, H, 2014)
"Radiation therapy with concomitant and adjuvant temozolomide (TMZ) is the standard therapy for nonelderly patients with glioblastoma."3.80Toxicity and outcome of radiotherapy with concomitant and adjuvant temozolomide in elderly patients with glioblastoma: a retrospective study. ( Mukasa, A; Narita, Y; Saito, K; Saito, N; Shibui, S; Shinoura, N; Tabei, Y, 2014)
"Following tumor resection, the majority of high-grade glioma (HGG) patients are treated with a combined modality regimen of radiotherapy and temozolomide."3.80Central neurotoxicity of standard treatment in patients with newly-diagnosed high-grade glioma: a prospective longitudinal study. ( Bosma, I; Buter, J; de Groot, M; Douw, L; Froklage, FE; Heimans, JJ; Klein, M; Lagerwaard, FJ; Oosterbaan, LJ; Postma, TJ; Reijneveld, JC; Sanchez, E; Sizoo, EM; Uitdehaag, BM, 2014)
"Patients with glioblastoma treated with BCNU wafer implantation for recurrence frequently receive frontline chemoradiotherapy with temozolomide as part of the Stupp protocol."3.80Evaluation of post-operative complications associated with repeat resection and BCNU wafer implantation in recurrent glioblastoma. ( Ewelt, C; Hänggi, D; Isik, G; Sabel, M; Samis Zella, MA; Schroeteler, J; Slotty, PJ; Steiger, HJ; Wallocha, M, 2014)
"To investigate the mechanisms of action of the tumoricidal effects of temozolomide against the human glioma cell line U251 in vitro, and to provide preclinical proof-of-concept studies of the effects of temozolomide-containing regimens."3.80Mechanism of temozolomide-induced antitumour effects on glioma cells. ( Hu, JA; Shen, W; Zheng, JS, 2014)
"Present work mainly evaluated the inhibitory effects of lidamycin (LDM), an enediyne antibiotic, on angiogenesis or glioma-induced angiogenesis in vitro and in vivo, especially its synergistic anti-angiogenesis with temozolomide (TMZ)."3.80Synergistic inhibition of angiogenesis and glioma cell-induced angiogenesis by the combination of temozolomide and enediyne antibiotic lidamycin. ( Li, XQ; Li, Y; Liu, H; Ouyang, ZG; Shang, Y; Zhang, SH; Zhen, YS, 2014)
"With standard treatment for glioblastoma (GBM) consisting of surgery followed by radiotherapy (RT) with concurrent and adjuvant temozolomide (TMZ), median survival is ~14."3.80Conditional probability of survival and post-progression survival in patients with glioblastoma in the temozolomide treatment era. ( Chung, C; Jiang, H; Laperriere, N; Lwin, Z; Mason, WP; McNamara, MG; Millar, BA; Sahgal, A, 2014)
"Wild-type or immunodeficient mice bearing intracranial glioblastoma multiforme or metastatic melanoma were treated with an intratumoral injection of Ad-Flt3L alone or in combination with the conditionally cytotoxic enzyme thymidine kinase (Ad-TK), followed by systemic administration of ganciclovir and temozolomide."3.80Temozolomide does not impair gene therapy-mediated antitumor immunity in syngeneic brain tumor models. ( Ahlzadeh, GE; Candolfi, M; Castro, MG; Ghiasi, H; Kamran, N; Lowenstein, PR; Paran, C; Puntel, M; Wibowo, M; Yagiz, K, 2014)
" In the present study aimed to: (i) evaluate the concordance between MGMT promoter methylation status in tumor tissue and plasma; (ii) monitor MGMT promoter methylation status in plasma taken before and during temozolomide treatment; (iii) explore the value of MGMT promoter methylation status in plasma as a prognostic/predictive biomarker in glioma patients."3.80MGMT promoter methylation in plasma of glioma patients receiving temozolomide. ( Cassoni, P; Castiglione, A; De Marco, L; Fiano, V; Gillio-Tos, A; Grasso, C; Magistrello, M; Merletti, F; Rudà, R; Sacerdote, C; Senetta, R; Soffietti, R; Tondat, F; Trevisan, E; Trevisan, M, 2014)
"Bevacizumab (BZM) and temozolomide (TMZ) have been shown to be beneficial in the treatment of patients with glioblastoma."3.80Odds of death after glioblastoma diagnosis in the United States by chemotherapeutic era. ( Wachtel, MS; Yang, S, 2014)
"Temozolomide profoundly prevented the outgrowth of experimental brain metastases of breast cancer in an MGMT-dependent manner."3.80Profound prevention of experimental brain metastases of breast cancer by temozolomide in an MGMT-dependent manner. ( Biernat, W; Duchnowska, R; Gril, B; Hewitt, SM; Hua, E; Jassem, J; Liewehr, DJ; Palmieri, D; Qian, Y; Sosińska-Mielcarek, K; Stark, AM; Steeg, PS; Steinberg, SM; Woditschka, S, 2014)
"Temozolomide (TMZ), used to treat glioblastoma and malignant glioma, induces autophagy, apoptosis and senescence in cancer cells."3.80Antitumor effect of fibrin glue containing temozolomide against malignant glioma. ( Anai, S; Hide, T; Kuratsu, J; Kuroda, J; Makino, K; Nakamura, H; Shinojima, N; Takezaki, T; Yano, S, 2014)
"We report the case of severe liver toxicity with jaundice during radiochemotherapy with temozolomide likely due to interaction with a popular Chinese herbal formula after surgery for glioblastoma."3.80Liver toxicity during temozolomide chemotherapy caused by Chinese herbs. ( Egle, A; Greil, R; Grundbichler, M; Hufnagl, C; Magnes, T; Melchardt, T; Moik, M; Strasser, M; Weiss, L, 2014)
"Temozolomide (TMZ) is widely used to treat glioblastoma multiforme (GBM)."3.80microRNA expression pattern modulates temozolomide response in GBM tumors with cancer stem cells. ( Bekar, A; Berghoff, AS; Budak, F; Cecener, G; Egeli, U; Kocaeli, H; Preusser, M; Ricken, G; Taskapılıoglu, MO; Tezcan, G; Tolunay, S; Tunca, B, 2014)
"Glioblastoma (GBM) remains the most aggressive and lethal brain tumor due to its molecular heterogeneity and high motility and invasion capabilities of its cells, resulting in high resistance to current standard treatments (surgery, followed by ionizing radiation combined with Temozolomide chemotherapy administration)."3.80Combined EGFR and autophagy modulation impairs cell migration and enhances radiosensitivity in human glioblastoma cells. ( Allavena, G; Angeletti, F; Comincini, S; Manai, F; Miracco, C; Palumbo, S; Pirtoli, L; Tini, P; Toscano, M, 2014)
"Autophagy is a cytoprotective process, which occurs following temozolomide (TMZ) treatment, and contributes to glioma chemoresistance and TMZ treatment failure."3.80Temozolomide induces autophagy via ATM‑AMPK‑ULK1 pathways in glioma. ( Li, B; Wang, Q; Wang, W; Xie, B; Zou, Y, 2014)
" We report a retrospective multicenter study of 97 consecutive adult patients with anaplastic astrocytoma (AA) treated with radiation therapy (RT) plus concomitant and adjuvant temozolomide (TMZ) between October 2004 and March 2012."3.80IDH1 mutation and MGMT methylation status predict survival in patients with anaplastic astrocytoma treated with temozolomide-based chemoradiotherapy. ( Arcella, A; Bozzao, A; Di Stefano, D; Enrici, RM; Esposito, V; Giangaspero, F; Lanzetta, G; Minniti, G; Pace, A; Salvati, M; Scaringi, C; Scarpino, S; Villani, V, 2014)
"Cyclophosphamide-dacarbazine-vincristine regimen is recommended for the treatment of malignant pheochromocytoma and paraganglioma (MPP); however, dacarbazine is the only recognized active drug in neuroendocrine tumours."3.80SDHB mutations are associated with response to temozolomide in patients with metastatic pheochromocytoma or paraganglioma. ( Al Ghuzlan, A; Amar, L; Baudin, E; Bertherat, J; Borget, I; Caramella, C; Chougnet, C; Déandreis, D; Deschamps, F; Dumont, F; Favier, J; Gimenez-Roqueplo, AP; Hadoux, J; Leboulleux, S; Letouzé, E; Libé, R; Loriot, C; Schlumberger, M; Scoazec, JY; Young, J, 2014)
"Temozolomide (TMZ)-resistance in glioblastoma multiforme (GBM) has been linked to upregulation of O(6)-methylguanine-DNA methyltransferase (MGMT)."3.80A nanoparticle carrying the p53 gene targets tumors including cancer stem cells, sensitizes glioblastoma to chemotherapy and improves survival. ( Chang, EH; Dagata, JA; Farkas, N; Kim, E; Kim, SS; Nishida, M; Pirollo, KF; Rait, A, 2014)
"Glioblastoma multiforme (GBM) represents the most common and deadly primary brain malignancy, particularly due to temozolomide (TMZ) and radiation (RT) resistance."3.80Kinomic exploration of temozolomide and radiation resistance in Glioblastoma multiforme xenolines. ( Anderson, JC; Bonner, JA; Bredel, M; Choradia, NV; Duarte, CW; Rohrbach, TD; Thottassery, JV; Welaya, K; Willey, CD; Yancey Gillespie, G; Yang, ES, 2014)
"Effective sensitizing strategies potentially can extend the benefit of temozolomide (TMZ) therapy in patients with glioblastoma (GBM)."3.80Discordant in vitro and in vivo chemopotentiating effects of the PARP inhibitor veliparib in temozolomide-sensitive versus -resistant glioblastoma multiforme xenografts. ( Bakken, KK; Boakye-Agyeman, F; Carlson, BL; Gupta, SK; Kizilbash, SH; Mladek, AC; Reid, J; Sarkaria, JN; Schroeder, MA, 2014)
"The present work evaluated the synergistic efficacy of an enediyne antibiotic lidamycin (LDM) plus temozolomide (TMZ) against glioma in vitro and in vivo."3.80Synergy of enediyne antibiotic lidamycin and temozolomide in suppressing glioma growth with potentiated apoptosis induction. ( Li, XQ; Li, Y; Liu, H; Ouyang, ZG; Shang, Y; Zhang, SH; Zhen, YS, 2014)
"To study the therapeutic effect of intranasal administration of temozolomide (TMZ) for brain-targeting delivery in a rat model bearing orthotopic C6 glioma xenografts."3.80[Intranasal administration of temozolomide for brain-targeting delivery: therapeutic effect on glioma in rats]. ( Gao, Y; Li, Y; Liu, G; Ma, L; Wang, Y; Zhou, X, 2014)
" The aim of this study was to investigate whether quercetin could sensitize human glioblastoma cells to temozolomide (TMZ) in vitro."3.80Quercetin sensitizes human glioblastoma cells to temozolomide in vitro via inhibition of Hsp27. ( Lan, Q; Li, RJ; Sang, DP, 2014)
"To analyze patterns of failure in patients with glioblastoma multiforme (GBM) treated with limited-margin radiation therapy and concurrent temozolomide."3.80Patterns of failure for glioblastoma multiforme following limited-margin radiation and concurrent temozolomide. ( Bag, AK; Dobelbower, MC; Ennis, WH; Fiveash, JB; Gebhardt, BJ; Markert, JM, 2014)
"To evaluate the role of bevacizumab and irinotecan as secondline treatment of glioblastoma in patients with progression after radiotherapy and temozolomide."3.80Bevacizumab as secondline treatment of glioblastoma -  worth the effort? ( Rovere, RK, 2014)
"We examined changes to key UPR modulators in temozolomide-sensitive and -resistant human GBM cells (D54 and U87) treated with/without temozolomide at different oxygen concentrations using western blotting, and cytotoxic benefits of overexpressing key chaperone, P4HB, in GBM cells (U87 and U251) under normoxia and hyperoxia."3.80Hyperoxia resensitizes chemoresistant glioblastoma cells to temozolomide through unfolded protein response. ( Ho, AS; Kiang, KM; Lee, D; Leung, GK; Sun, S; Xu, FF; Zhang, XQ, 2014)
"This study explored the effects of telomerase reverse transcriptase (TERT) promoter mutations on transcriptional activity of the TERT gene under hypoxic and temozolomide (TMZ) treatment conditions, and investigated the status and prognostic value of these mutations in gliomas."3.80TERT promoter mutations lead to high transcriptional activity under hypoxia and temozolomide treatment and predict poor prognosis in gliomas. ( Chen, C; Han, S; Li, Z; Meng, L; Wu, A; Zhang, X, 2014)
"Eighteen patients with newly diagnosed, histologically confirmed glioblastoma had 3D-MR proton spectroscopic imaging (MRSI) along with T2 and T1 gadolinium-enhanced MR images at simulation and at boost treatment planning after 17 to 20 fractions of radiation therapy."3.803-Dimensional magnetic resonance spectroscopic imaging at 3 Tesla for early response assessment of glioblastoma patients during external beam radiation therapy. ( Anderson, CM; Bayouth, JE; Buatti, JM; Capizzano, AA; Clerkin, PP; Magnotta, V; McGuire, SM; Morris, A; Muruganandham, M; Smith, BJ; Smith, MC, 2014)
"This study assesses the controversial role of temozolomide (TMZ) concurrent with adjuvant radiation (RT) in patients with anaplastic astrocytoma (AA)."3.80The impact of concurrent temozolomide with adjuvant radiation and IDH mutation status among patients with anaplastic astrocytoma. ( Buckner, JC; Decker, PA; Giannini, C; Hardie, J; Jenkins, RB; Kizilbash, SH; Laack, NN; Parney, IF; Uhm, JH; Voss, JS, 2014)
"The EORTC-NCIC regimen for glioblastoma requires different dosing of temozolomide (TMZ) during radiation and maintenance therapy."3.80Analyzing temozolomide medication errors: potentially fatal. ( Bressler, LR; Gabay, MP; Letarte, N; Long, KE; Stachnik, JM; Villano, JL, 2014)
"This study evaluated the toxicity profiles of temozolomide in the treatment of malignant glioma as either concurrent or adjuvant chemotherapy."3.80Toxicity profile of temozolomide in the treatment of 300 malignant glioma patients in Korea. ( Bae, SH; Cho, SY; Kim, CY; Kim, TM; Kim, YH; Kim, YJ; Lee, MM; Lee, SH; Park, CK; Park, MJ, 2014)
"The combined application of aplysin and TMZ significantly sensitizes glioma cells to TMZ action, compared with TMZ alone."3.80Aplysin enhances temozolomide sensitivity in glioma cells by increasing miR-181 level. ( Ge, N; Gong, A; Liang, H; Lu, L; Yao, W, 2014)
"The aim of the present study was to evaluate the toxicity and clinical outcome of radio-chemotherapy with temozolomide in patients with glioblastoma aged more than 65 years."3.80Radio-chemotherapy with temozolomide in elderly patients with glioblastoma. A mono-institutional experience. ( Cocuzza, P; Fabbrini, MG; Fatigante, L; Ferrazza, P; Monzani, F; Pasqualetti, F; Pasqualetti, G, 2014)
"The current standard of care for glioblastoma (GBM) involves a combination of surgery, radiotherapy, and temozolomide chemotherapy, but this regimen fails to achieve long-term tumor control."3.80Novel MSH6 mutations in treatment-naïve glioblastoma and anaplastic oligodendroglioma contribute to temozolomide resistance independently of MGMT promoter methylation. ( Cairncross, JG; Luchman, HA; Lun, XQ; Nguyen, SA; Robbins, SM; Senger, DL; Stechishin, OD; Weiss, S, 2014)
" Finally, human T98G glioblastoma cells that are resistant to the chemotherapy drug temozolomide (TMZ) showed a unique high expression of the Na+/K+-ATPase α2 and α3 subunits compared to the TMZ-sensitive cell line LN229 and normal human astrocytes."3.80Inhibition of Na+/K+-ATPase induces hybrid cell death and enhanced sensitivity to chemotherapy in human glioblastoma cells. ( Chen, D; Mohamad, O; Song, M; Yu, SP, 2014)
"To review clinical outcomes of moderate dose escalation using high-dose radiation therapy (HDRT) in the setting of concurrent temozolomide (TMZ) in patients with newly diagnosed glioblastoma multiforme (GBM), compared with standard-dose radiation therapy (SDRT)."3.80Radiation therapy dose escalation for glioblastoma multiforme in the era of temozolomide. ( Badiyan, SN; Chicoine, MR; Dacey, R; DeWees, T; Dowling, JL; Huang, J; Jalalizadeh, R; Kim, AH; Leuthardt, EC; Linette, G; Markovina, S; Rich, KM; Robinson, CG; Simpson, JR; Tran, DD; Zipfel, GJ, 2014)
"These results suggest that concomitant treatment with NPe6-PDT and temozolomide is a potentially useful therapy for glioma."3.80Concomitant treatment with temozolomide enhances apoptotic cell death in glioma cells induced by photodynamic therapy with talaporfin sodium. ( Akimoto, J; Beppu, M; Fujiwara, Y; Hiranuma, M; Hironaka, C; Miki, Y; Moritake, K; Omata, H, 2014)
" Next, we treated all eGFP/Luc GBM cell lines with Temozolomide (TMZ) or Doxorubicin, comparing co-cultures of glioblastoma (GBM) cells and TNC-1 astrocytes with mono-cultures of eGFP/Luc GBM cells."3.80A co-culture model with brain tumor-specific bioluminescence demonstrates astrocyte-induced drug resistance in glioblastoma. ( Costea, DE; Enger, PØ; Huang, B; Leiss, L; Li, X; Liang, X; Sakariassen, PØ; Skaftnesmo, KO; Wang, J; Yan, T; Yang, N; Zhu, H, 2014)
"Twenty-three consecutive high-grade glioma patients were treated with radiotherapy (2 Gy/60 Gy) with concomitant and adjuvant temozolomide."3.80ADC texture--an imaging biomarker for high-grade glioma? ( Asklund, T; Birgander, R; Brynolfsson, P; Garpebring, A; Hauksson, J; Henriksson, R; Karlsson, M; Nilsson, D; Nyholm, T; Trygg, J, 2014)
"We report the safety and feasibility of a 3 days on/11 days off temozolomide regimen for the treatment of recurrent malignant gliomas."3.80Retrospective analysis of safety and feasibility of a 3 days on/11 days off temozolomide dosing regimen in recurrent adult malignant gliomas. ( Brown, BD; Brown, T; Juarez, T; Kesari, S; Piccioni, DE; Saria, MG; van Vugt, VA, 2014)
"Prophylaxis against Pneumocystis jiroveci pneumonia (PJP) is currently recommended for patients receiving chemoradiation with temozolomide for newly diagnosed glioblastoma multiforme."3.80Incidence of Pneumocystis jirovecii pneumonia after temozolomide for CNS malignancies without prophylaxis. ( Barnes, PD; Bubalo, J; Fu, R; Gahramanov, S; Lacy, C; Nasseri, M; Neuwelt, AJ; Neuwelt, EA; Nguyen, TM; Tyson, RM, 2014)
"To assess the prognosis predictability of a measurable enhancing lesion using histogram parameters produced by the normalized cerebral blood volume (nCBV) and normalized apparent diffusion coefficient (nADC) after completion of standard concomitant chemoradiotherapy (CCRT) and adjuvant temozolomide (TMZ) medication in glioblastoma multiforme (GBM) patients."3.80Prognosis prediction of measurable enhancing lesion after completion of standard concomitant chemoradiotherapy and adjuvant temozolomide in glioblastoma patients: application of dynamic susceptibility contrast perfusion and diffusion-weighted imaging. ( Choi, SH; Kim, IH; Kim, JH; Kim, TM; Lee, SH; Park, CK; Park, SH; Ryoo, I; Sohn, CH; Yun, TJ, 2014)
"Temozolomide, an oral alkylating agent, is used in the treatment of glioblastoma."3.80Vanishing bile duct syndrome in the context of concurrent temozolomide for glioblastoma. ( Adeyi, O; Fung, S; Mason, M; Millar, BA, 2014)
"The objective of this study was to report the authors' experience with the long-term administration of temozolomide (TMZ; > 6 cycles, up to 101) in patients with newly diagnosed glioblastoma and to analyze its feasibility and safety as well as its impact on survival."3.80Long-term therapy with temozolomide is a feasible option for newly diagnosed glioblastoma: a single-institution experience with as many as 101 temozolomide cycles. ( Albanese, V; Barbagallo, GM; Caltabiano, R; Certo, F; Lanzafame, S; Longo, A; Motta, F; Palmucci, S; Paratore, S; Parra, HS; Privitera, G; Scaglione, G, 2014)
"For glioma, temozolomide (TMZ) is a commonly used chemotherapy drug and photodynamic therapy (PDT) is an important adjuvant therapy."3.80Combination of photodynamic therapy and temozolomide on glioma in a rat C6 glioma model. ( Guo, M; Hu, S; Shen, L; Zhang, X, 2014)
" Temozolomide (TMZ) is an alkylating agent used for the treatment of glioblastoma multiforme (GBM), the most common and deadliest of malignant primary brain tumors."3.80Glioblastoma multiforme and hepatitis B: do the right thing(s). ( Begini, P; Delle Fave, G; Gallina, S; Marignani, M; Minniti, G; Purchiaroni, F, 2014)
"Nine post-temozolomide recurrent or progressive high-grade glioma patients (seven with glioblastoma and two with anaplastic astrocytoma) were treated with BV monotherapy."3.80Predictive significance of mean apparent diffusion coefficient value for responsiveness of temozolomide-refractory malignant glioma to bevacizumab: preliminary report. ( Kobayashi, K; Nagane, M; Shimizu, S; Shiokawa, Y; Shishido-Hara, Y; Tanaka, M; Tsuchiya, K, 2014)
"The benefit of the introduction of alkylating chemotherapy in the treatment of glioblastoma multiforme (GBM) patients has been demonstrated by comparing radiotherapy with concomitant plus intermittent temozolomide (iTMZ) to radiation therapy."3.79The impact of sequential vs. combined radiochemotherapy with temozolomide, resection and MGMT promoter hypermethylation on survival of patients with primary glioblastoma--a single centre retrospective study. ( Felsberg, J; Goeppert, M; Rapp, M; Sabel, M; Steiger, HJ, 2013)
"Temozolomide (TMZ) is important chemotherapy for glioblastoma multiforme (GBM), but the optimal dosing schedule is unclear."3.79Efficacy of protracted temozolomide dosing is limited in MGMT unmethylated GBM xenograft models. ( Anderson, SK; Ballman, KV; Carlson, BL; Cen, L; Decker, PA; Giannini, C; Grogan, PT; Kitange, GJ; Mladek, AC; Pokorny, JL; Sarkaria, JN; Schroeder, MA; Wu, W, 2013)
" In this study, we investigated the predictive value of SLC22A18 promoter methylation and protein expression in glioblastoma multiforme (GBM) patients receiving temozolomide (TMZ) therapy."3.79Predictive value of the SLC22A18 protein expression in glioblastoma patients receiving temozolomide therapy. ( Chu, SH; Feng, DF; Jiang, PC; Li, ZQ; Ma, YB, 2013)
"Temozolomide (TMZ) is commonly used in the treatment of glioblastoma (GBM)."3.79Effect of lomeguatrib-temozolomide combination on MGMT promoter methylation and expression in primary glioblastoma tumor cells. ( Canpinar, H; Castresana, JS; Ilgaz, S; Ozdemir, M; Ozkan, T; Oztuna, D; Rey, JA; Sunguroğlu, A; Taspinar, M; Ugur, HC, 2013)
"Valproic acid (VA) is an antiepileptic drug (AED) and histone deacetylase (HDAC) inhibitor taken by patients with glioblastoma (GB) to manage seizures, and it can modulate the biologic effects of radiation therapy (RT)."3.79Valproic acid use during radiation therapy for glioblastoma associated with improved survival. ( Barker, CA; Beal, K; Bishop, AJ; Chan, TA; Chang, M, 2013)
"The purpose of this study is to assess the preclinical therapeutic efficacy of magnetic resonance imaging (MRI)-monitored focused ultrasound (FUS)-induced blood-brain barrier (BBB) disruption to enhance Temozolomide (TMZ) delivery for improving Glioblastoma Multiforme (GBM) treatment."3.79Focused ultrasound-induced blood-brain barrier opening to enhance temozolomide delivery for glioblastoma treatment: a preclinical study. ( Chen, PY; Chu, PC; Feng, LY; Hsu, PW; Huang, CY; Lee, PY; Liu, HL; Lu, YJ; Tsai, HC; Tseng, IC; Wang, HY; Wei, KC; Yen, TC, 2013)
" In addition, microsatellite instability, leading to the putative mechanism of temozolomide (TMZ) resistance, was frequently detected."3.79Pediatric glioblastoma with oligodendroglioma component: aggressive clinical phenotype with distinct molecular characteristics. ( Amano, T; Fujioka, Y; Hata, N; Iwaki, T; Mizoguchi, M; Murata, H; Nakamizo, A; Sasaki, T; Suzuki, SO; Yoshimoto, K, 2013)
"We investigated the pattern of failure in glioblastoma multiforma (GBM) patients treated with concurrent radiation, bevacizumab (BEV), and temozolomide (TMZ)."3.79Concurrent bevacizumab and temozolomide alter the patterns of failure in radiation treatment of glioblastoma multiforme. ( Kadner, R; Shields, LB; Spalding, AC; Vitaz, TW, 2013)
"We have studied the consequences of the combination of the mammalian target of rapamycin (mTOR) inhibitor RAD001 and temozolomide on the growth and cell death of the glioblastoma cell line U-87 in vitro."3.79The mTOR inhibitor RAD001 potentiates autophagic cell death induced by temozolomide in a glioblastoma cell line. ( Bischoff, P; Burckel, H; Josset, E; Noël, G, 2013)
"To determine whether immediate post-operative brachytherapy can be safely applied to newly diagnosed glioblastomas to retard tumor progression prior to initiation of external beam radiation therapy (EBRT) and temozolomide."3.79Immediate post-operative brachytherapy prior to irradiation and temozolomide for newly diagnosed glioblastoma. ( Alksne, JF; Carter, BS; Chen, CC; Gonda, DD; Lawson, J; Murphy, K; Rose, B; Russell, M; Scanderbeg, DJ; Waters, JD, 2013)
"Pseudoprogression is a frequent phenomenon observed since the introduction of postoperative therapy with radiotherapy and temozolomide (RT/TMZ) in glioblastoma multiforme (GBM) patients."3.79Defining pseudoprogression in glioblastoma multiforme. ( Bechter, OE; Clement, PM; De Vleeschouwer, S; Demaerel, P; Geussens, Y; Menten, J; Sciot, R; Van Calenbergh, F; Van Gool, S; Van Mieghem, E; Wilms, G; Wozniak, A, 2013)
"To examine the efficacy of valproic acid (VPA) given either with or without levetiracetam (LEV) on seizure control and on survival in patients with glioblastoma multiforme (GBM) treated with chemoradiation."3.79Effect of valproic acid on seizure control and on survival in patients with glioblastoma multiforme. ( Dielemans, JC; Kerkhof, M; Taphoorn, MJ; van Breemen, MS; Vecht, CJ; Walchenbach, R; Zwinkels, H, 2013)
" The alkylating agent temozolomide (TMZ) has been shown to improve the overall survival in patients with malignant gliomas, especially in tumors with methylated promoter of the O6-methylguanine-DNA-methyltransferase (MGMT) gene."3.79Restoration of sensitivity in chemo-resistant glioma cells by cold atmospheric plasma. ( Boxhammer, V; Klämpfl, TG; Köritzer, J; Li, YF; Morfill, GE; Schäfer, A; Schlegel, J; Schwenk-Zieger, S; Shimizu, T; Welz, C; Zimmermann, JL, 2013)
"Global gene expressions and drug sensitivities to three chemotherapeutic drugs (imatinib, camptothecin and temozolomide) were measured in six human glioblastoma-derived cell lines."3.79Synergistic interactions between camptothecin and EGFR or RAC1 inhibitors and between imatinib and Notch signaling or RAC1 inhibitors in glioblastoma cell lines. ( Andersson, C; Bergqvist, M; Blomquist, E; Ekman, S; Gullbo, J; Isaksson, A; Johansson, F; Kultima, HG; Lennartsson, J; Sooman, L, 2013)
"To explore the role of histogram analysis of apparent diffusion coefficient (ADC) maps obtained at standard- and high-b-value (1000 and 3000 sec/mm(2), respectively) diffusion-weighted (DW) imaging in the differentiation of true progression from pseudoprogression in glioblastoma treated with radiation therapy and concomitant temozolomide."3.79Differentiation of true progression from pseudoprogression in glioblastoma treated with radiation therapy and concomitant temozolomide: comparison study of standard and high-b-value diffusion-weighted imaging. ( Choi, SH; Chu, HH; Jung, SC; Kim, IH; Kim, JH; Kim, SC; Kim, TM; Lee, AL; Lee, SH; Park, CK; Park, SH; Ryoo, I; Shin, H; Sohn, CH; Yeom, JA; Yoon, TJ, 2013)
"Glioblastomas are the most frequent and aggressive intracranial neoplasms in humans, and despite advances and the introduction of the alkylating agent temozolomide in therapy have improved patient survival, resistance mechanisms limit benefits."3.79Extracellular sphingosine-1-phosphate: a novel actor in human glioblastoma stem cell survival. ( Caroli, M; Condomitti, G; Di Vito, C; Galli, R; Giussani, P; Riboni, L; Riccitelli, E; Tringali, C; Viani, P, 2013)
"To evaluate the efficacy of pulsed low-dose radiation therapy (PLRT) combined with temozolomide (TMZ) as a novel treatment approach for radioresistant glioblastoma multiforme (GBM) in a murine model."3.79Pulsed versus conventional radiation therapy in combination with temozolomide in a murine orthotopic model of glioblastoma multiforme. ( Chunta, JL; Grills, IS; Huang, J; Krueger, SA; Lee, DY; Marples, B; Martinez, AA; Park, SS; Wilson, GD, 2013)
"Addition of temozolomide (TMZ) to radiation therapy is the standard treatment for patients with glioblastoma (GBM)."3.79Early assessment of the efficacy of temozolomide chemotherapy in experimental glioblastoma using [18F]FLT-PET imaging. ( Faber, C; Jacobs, AH; Kopka, K; Kuhlmann, M; Schäfers, M; Schelhaas, S; Schwegmann, K; Viel, T; Wachsmuth, L; Wagner, S, 2013)
" Such chemoresistance was overcome by apparently noncytotoxic doses of temozolomide, which chemosensitized glioblastoma cells to doxorubicin, vinblastine, and etoposide."3.79Temozolomide downregulates P-glycoprotein expression in glioblastoma stem cells by interfering with the Wnt3a/glycogen synthase-3 kinase/β-catenin pathway. ( Annovazzi, L; Bosia, A; Caldera, V; Campia, I; Ghigo, D; Kopecka, J; Mellai, M; Riganti, C; Salaroglio, IC; Schiffer, D, 2013)
"Radiotherapy with concomitant and adjuvant temozolomide (six cycles) is the standard treatment after surgery in glioblastoma patients."3.79Prolonged administration of adjuvant temozolomide improves survival in adult patients with glioblastoma. ( Baumann, C; Beauchesne, P; Blonski, M; Chauffert, B; Darlix, A; Ghiringhelli, F; Lorgis, V; Pinelli, C; Rech, F; Taillandier, L; Zouaoui, S, 2013)
"To compare retrospectively outcome after photon radiotherapy alone, radiochemotherapy with temozolomide (TMZ), and carbon ion radiotherapy in patients with high-grade gliomas and to generate a hypothetical outcome curve for C12 and TMZ."3.79Comparison of carbon ion radiotherapy to photon radiation alone or in combination with temozolomide in patients with high-grade gliomas: explorative hypothesis-generating retrospective analysis. ( Bruckner, T; Combs, SE; Debus, J; Kamada, T; Kieser, M; Mizoe, JE; Tsujii, H, 2013)
"Standard treatment for glioblastoma (GBM) is surgery followed by radiation (RT) and temozolomide (TMZ)."3.79Chemoirradiation for glioblastoma multiforme: the national cancer institute experience. ( Camphausen, K; Fine, HA; Ho, J; Iwamoto, F; Kim, L; Krauze, A; Kreisl, T; McNeil, K; Ning, H; Ondos, J; Shankavaram, U; Smith, S; Sul, J, 2013)
"The recent progress in chemotherapy for malignant gliomas is attributable to the introduction of the DNA-methylating agent temozolomide (TMZ); however, drug resistance remains a major issue."3.79The Cdk inhibitor flavopiridol enhances temozolomide-induced cytotoxicity in human glioma cells. ( Adachi, K; Hayashi, T; Hirose, Y; Ohba, S, 2013)
"A retrospective analysis was conducted to identify patients (N=117) who received standard oral temozolomide for glioblastoma at our institution from 2003 to 2010."3.79An automated system for detecting nonadherence in laboratory testing and monitoring for myelosuppression in patients receiving self-administered oral chemotherapy. ( Carter, AF; DeTroye, AT; Harmon, MS; Lesser, GJ; Morrell, RM; Tooze, JA, 2013)
" Temozolomide (TMZ) with radiation is the most frequently used first-line treatment for patients with glioblastoma, the most common and aggressive form of primary brain cancer in adults."3.79Toca 511 gene transfer and 5-fluorocytosine in combination with temozolomide demonstrates synergistic therapeutic efficacy in a temozolomide-sensitive glioblastoma model. ( Espinoza, FL; Gruber, HE; Gunzburg, W; Hlavaty, J; Huang, TT; Ibañez, CE; Jolly, DJ; Kasahara, N; Martin, B; Ostertag, D; Pertschuk, D; Petznek, H; Robbins, JM; Rodriguez-Aguirre, M, 2013)
"Temozolomide (TMZ) during and after radiotherapy (RT) is recommended for patients with newly diagnosed glioblastoma (GBM)."3.79Glioblastoma management in the temozolomide era: have we improved outcome? ( Al-Zahrani, A; Atenafu, E; Laperriere, N; Lwin, Z; MacFadden, D; Mason, WP; Menard, C; Miller, BA; Sahgal, A, 2013)
"The effect of concomitant and adjuvant temozolomide in glioblastoma patients above the age of 65 years lacks evidence."3.79Concomitant and adjuvant temozolomide of newly diagnosed glioblastoma in elderly patients. ( Behm, T; Bock, HC; Horowski, A; Mielke, D; Rohde, V; Schneider, S; Stockhammer, F, 2013)
"Although implementation of temozolomide (TMZ) as a part of primary therapy for glioblastoma multiforme (GBM) has resulted in improved patient survival, the disease is still incurable."3.79Clinical variables serve as prognostic factors in a model for survival from glioblastoma multiforme: an observational study of a cohort of consecutive non-selected patients from a single institution. ( Broholm, H; Christensen, IJ; Grunnet, K; Kosteljanetz, M; Michaelsen, SR; Poulsen, HS; Stockhausen, MT, 2013)
"In 2005, maximum safe surgical resection, followed by radiotherapy with concomitant temozolomide (TMZ), followed by adjuvant TMZ became the standard of care for glioblastoma (GBM)."3.79Time trends in glioblastoma multiforme survival: the role of temozolomide. ( Darefsky, AS; Dubrow, R; Jacobs, DI; King, JT; Laurans, MS; Park, LS; Rose, MG, 2013)
"To examine whether adjuvant temozolomide treatment improved glioblastoma patients` survival in a large Canadian cohort."3.79Effectiveness of adjuvant temozolomide treatment in patients with glioblastoma. ( Al-Nuaimi, SK; Alnaami, IM; Gourishankar, S; Mehta, V; Murtha, AD; Senthilselvan, A; Walling, S, 2013)
" Human glioblastoma is highly resistant to chemotherapy with temozolomide."3.79Lobarstin enhances chemosensitivity in human glioblastoma T98G cells. ( Chung, H; Jo, S; Kim, IC; Kim, S; Kim, TU; Lee, H; Yim, JH, 2013)
"To analyze initial recurrence patterns in patients with newly diagnosed glioblastoma after radiotherapy plus concurrent and adjuvant temozolomide, and to investigate cumulative recurrence patterns after salvage treatment, including surgery, stereotactic radiotherapy, and chemotherapy."3.79Initial and cumulative recurrence patterns of glioblastoma after temozolomide-based chemoradiotherapy and salvage treatment: a retrospective cohort study in a single institution. ( Arakawa, Y; Hiraoka, M; Miyamoto, S; Mizowaki, T; Ogura, K; Ogura, M; Sakanaka, K, 2013)
" Here, we report for the first time that the second mitochondria-derived activator of caspases (Smac) mimetic BV6 sensitizes glioblastoma cells toward Temozolomide (TMZ), the first-line chemotherapeutic agent in the treatment of glioblastoma."3.79Smac mimetic sensitizes glioblastoma cells to Temozolomide-induced apoptosis in a RIP1- and NF-κB-dependent manner. ( Cristofanon, S; Debatin, KM; Deshayes, K; Fulda, S; Karl, S; Marschall, V; Vucic, D; Wagner, L; Zobel, K, 2013)
" We retrospectively surveyed 32 patients with GBM or GBM with oligodendroglioma component (GBMO) who underwent biopsy or maximal tumor resection followed by concurrent radiotherapy and temozolomide (TMZ)."3.79IDH1 mutation as a potential novel biomarker for distinguishing pseudoprogression from true progression in patients with glioblastoma treated with temozolomide and radiotherapy. ( Houkin, K; Kamoshima, Y; Kobayashi, H; Motegi, H; Murata, J; Tanino, M; Terasaka, S; Yamaguchi, S, 2013)
"Clinical studies in patients with newly diagnosed glioblastoma treated with temozolomide have shown that the methylation status of the O(6)-methylguanine-DNA methyltransferase (MGMT) gene is both predictive and prognostic of outcome."3.79The T genotype of the MGMT C>T (rs16906252) enhancer single-nucleotide polymorphism (SNP) is associated with promoter methylation and longer survival in glioblastoma patients. ( Brewer, J; Hitchins, MP; Kuroiwa-Trzmielina, J; Lu, D; McDonald, KL; Nozue, K; Olivier, J; Rapkins, RW; Tiwari, S; Wheeler, HR; Zhao, L, 2013)
"We investigated whether high levels of activated mitogen-activated protein kinase (p-MAPK) were associated with poor survival among patients with newly diagnosed glioblastoma during the temozolomide era."3.79High levels of phosphorylated MAP kinase are associated with poor survival among patients with glioblastoma during the temozolomide era. ( Bannykh, SI; Black, KL; Carico, C; Dantis, J; Elramsisy, A; Fan, X; Hu, J; Mukherjee, D; Nuño, M; Patil, CG; Yu, JS, 2013)
" This study aimed to investigate the possible mechanism of mutant TP53 inducing temozolomide resistance in glioblastoma cells."3.79Mutant TP53 enhances the resistance of glioblastoma cells to temozolomide by up-regulating O(6)-methylguanine DNA-methyltransferase. ( Chen, JX; Liu, YH; Mao, Q; Wang, X; You, C, 2013)
" In previous studies the alkylating agent temozolomide (TMZ) incorporated into a polymer, pCPP:SA, also for local delivery, and OncoGel were individually shown to increase efficacy in a rat glioma model."3.79Combination of paclitaxel thermal gel depot with temozolomide and radiotherapy significantly prolongs survival in an experimental rodent glioma model. ( Brem, H; Eberhart, CG; Fowers, KD; Hwang, L; Li, KW; Okonma, S; Recinos, VR; Tyler, BM; Vellimana, AK; Zhang, Y, 2013)
"To compare survival and hematological toxicity rates between two postoperative therapy regimens in patients with primary glioblastoma (GBM), namely temozolomide (TMZ) concomitant to radiation, followed by adjuvant TMZ, versus adjuvant TMZ after radiation only."3.79Toxicity and survival in primary glioblastoma patients treated with concomitant plus adjuvant temozolomide versus adjuvant temozolomide: results of a single-institution, retrospective, matched-pair analysis. ( Bock, HC; Brück, W; Giese, A; Gutenberg, A; Reifenberger, G, 2013)
" MRSI and CE abnormalities are now integrated for glioblastoma SIB-IMRT, concomitant with temozolomide, in an ongoing multi-institutional phase-III clinical trial."3.79Integration method of 3D MR spectroscopy into treatment planning system for glioblastoma IMRT dose painting with integrated simultaneous boost. ( Berry, I; Cassol, E; Celsis, P; Cohen-Jonathan, EM; Delannes, M; Filleron, T; Franceries, X; Ken, S; Laprie, A; Lotterie, JA; Lubrano, V; Simon, L; Supper, C; Vieillevigne, L, 2013)
"We evaluated the predictive value of O6-methylguanine-DNA methyltransferase (MGMT) protein expression and MGMT promoter methylation status in glioblastomas (GBM) treated with temozolomide (TMZ) in a Taiwan medical center."3.79Exclusion of histiocytes/endothelial cells and using endothelial cells as internal reference are crucial for interpretation of MGMT immunohistochemistry in glioblastoma. ( Chang-Chien, YC; Chen, MH; Guo, WY; Ho, DM; Ho, HL; Hsu, CY; Hsu, SP; Lin, SC; Yen, YS, 2013)
" Temozolomide is an alkylating agent approved for treating malignant gliomas."3.79Impact of temozolomide on gonadal function in patients with primary malignant brain tumors. ( Blackwood, R; Brown, M; Harmon, M; Lesser, G; Lovato, J; Strowd, RE; Yalcinkaya, T, 2013)
"We retrospectively reviewed nine cases of relapsed medulloblastoma treated with bevacizumab, irinotecan, ± temozolomide."3.79Response to bevacizumab, irinotecan, and temozolomide in children with relapsed medulloblastoma: a multi-institutional experience. ( Aguilera, D; Castellino, RC; Fangusaro, J; Hayes, LL; Kim, S; MacDonald, TJ; Mazewski, C; McNall-Knapp, RY, 2013)
"Glioblastoma (GBM), one of the most malignant human neoplasias, responds poorly to current treatment modalities, with temozolomide (TMZ) being the drug most frequently used for its treatment."3.79Tetra-O-methyl nordihydroguaiaretic acid, an inhibitor of Sp1-mediated survivin transcription, induces apoptosis and acts synergistically with chemo-radiotherapy in glioblastoma cells. ( Borges, KS; Carlotti, CG; Castro-Gamero, AM; de Oliveira, HF; de Paula Gomes Queiroz, R; Fujinami, MM; Moreno, DA; Scrideli, CA; Suazo, VK; Tone, LG, 2013)
"For elderly patients with glioblastoma multiforme (GBM), radiotherapy plus concomitant and adjuvant temozolomide has resulted in longer survival."3.79Performance status during and after radiotherapy plus concomitant and adjuvant temozolomide in elderly patients with glioblastoma multiforme. ( Jang, WY; Jeong, EH; Jung, S; Jung, TY; Kim, IY; Lee, JH; Moon, KS, 2013)
"The goal of this study was to investigate whether the amount of hypointense signal on susceptibility-weighted imaging within the contrast-enhancing lesion (%SWI-h) on the pretreatment scan could determine response in patients with newly diagnosed glioblastoma multiforme who received external beam radiation therapy with concomitant anti-angiogenic therapy (enzastaurin) and cytotoxic chemotherapy (temozolomide)."3.79Using susceptibility-weighted imaging to determine response to combined anti-angiogenic, cytotoxic, and radiation therapy in patients with glioblastoma multiforme. ( Butowski, N; Cha, S; Chang, SM; Essock-Burns, E; Lupo, JM; Molinaro, AM; Nelson, SJ, 2013)
"After previous treatment with standard radiotherapy (with or without temozolomide) patients with recurrent malignant glioma received bevacizumab (10 mg/kg intravenous) on Day 1 and Day 15 during radiotherapy."3.78Irradiation and bevacizumab in high-grade glioma retreatment settings. ( Belka, C; Ertl, L; Ganswindt, U; Geisler, J; Kreth, FW; la Fougère, C; Linn, J; Niyazi, M; Schwarz, SB; Siefert, A; Tonn, JC, 2012)
"To evaluate pathologically confirmed incidence of pseudoprogression and its impact on survival in glioblastoma multiforme (GBM) patients treated with radiotherapy and concurrent temozolomide (TMZ), followed by 6 months of TMZ maintenance therapy."3.78Pseudoprogression in patients with glioblastoma multiforme after concurrent radiotherapy and temozolomide. ( Oymak, E; Parlak, C; Pehlivan, B; Topkan, E; Topuk, S, 2012)
"We report retrospective data on the feasibility and efficacy of prolonging adjuvant temozolomide (TMZ) more than 6 months after chemoradiotherapy completion in patients with glioblastoma (GBM)."3.78Prolonged temozolomide for treatment of glioblastoma: preliminary clinical results and prognostic value of p53 overexpression. ( Auberdiac, P; Cartier, L; Chargari, C; Forest, F; Fotso, MJ; Magné, N; Malkoun, N; Nuti, C; Pacaut, C; Peoc'h, M; Schmitt, T; Thorin, J, 2012)
"Temozolomide (TMZ) is given in addition to radiotherapy in glioma patients, but its interaction with the commonly prescribed antiepileptic drug valproic acid (VPA) is largely unknown."3.78Valproic acid sensitizes human glioma cells for temozolomide and γ-radiation. ( Lafleur, MV; Slotman, BJ; Sminia, P; Stalpers, LJ; Van den Berg, J; Van Nifterik, KA, 2012)
"The standard-of-care treatment for newly diagnosed glioblastoma changed in 2005, when radiation therapy plus temozolomide chemotherapy replaced radiation therapy alone."3.78Glioblastoma survival in the United States before and during the temozolomide era. ( Johnson, DR; O'Neill, BP, 2012)
"To determine the maximum-tolerated dose (MTD) of radiation (RT) with concurrent temozolomide in patients with newly diagnosed glioblastoma (GBM), to estimate their progression-free (PFS) and overall survival (OS), and to assess the role of (11)C methionine PET (MET-PET) imaging in predicting recurrence."3.78Concurrent temozolomide and dose-escalated intensity-modulated radiation therapy in newly diagnosed glioblastoma. ( Brown, D; Cao, Y; Chenevert, T; Gomez-Hassan, D; Heth, J; Junck, L; Lawrence, T; Normolle, D; Piert, M; Schipper, M; Ten Haken, RK; Tsien, CI, 2012)
"The alkylating agent temozolomide (TMZ) is the major chemotherapeutic drug used clinically in the treatment of malignant gliomas."3.78Resveratrol enhances the therapeutic effect of temozolomide against malignant glioma in vitro and in vivo by inhibiting autophagy. ( Lee, CC; Lin, CJ; Lin, TY; Lin, YF; Shih, CM; Shih, YL; Wang, SH, 2012)
"Although both the alkylating agent temozolomide (TMZ) and oncolytic viruses hold promise for treating glioblastoma, which remains uniformly lethal, the effectiveness of combining the two treatments and the mechanism of their interaction on cancer stem cells are unknown."3.78Oncolytic virus-mediated manipulation of DNA damage responses: synergy with chemotherapy in killing glioblastoma stem cells. ( Hirose, Y; Kanai, R; Louis, DN; Martuza, RL; Rabkin, SD; Sgubin, D; Wakimoto, H; Yip, S; Zaupa, CM, 2012)
"We prospectively analyzed 65 patients suffering from glioblastoma (GBM) who underwent radiotherapy with concomitant adjuvant temozolomide."3.78Volumetric and MGMT parameters in glioblastoma patients: survival analysis. ( Chatzisotiriou, A; Eleftheraki, AG; Fountzilas, G; Iliadis, G; Kotoula, V; Lambaki, S; Misailidou, D; Selviaridis, P; Televantou, D, 2012)
"Standard treatment for glioblastoma multiforme (GBM) changed in 2005 when addition of temozolomide (TMZ) to maximal surgical resection followed by radiation therapy (RT) was shown to prolong survival in a clinical trial."3.78Patterns of care and survival for patients with glioblastoma multiforme diagnosed during 2006. ( Abrams, J; Harlan, L; Mann, B; Yabroff, KR; Zeruto, C, 2012)
"To illustrate this, we report the case of a 60-year-old male patient confronted with an inoperable glioblastoma multiforme on the splenium of the corpus callosum, of poor prognosis, treated by concomitant radiochemotherapy with temozolomide, who developed psychotic depression with Cotard's syndrome."3.78Cotard's syndrome with glioblastoma multiforme. ( Comet, B; Le Rhun, E; Ramirez, C; Reich, M, 2012)
"The standard of care for newly diagnosed glioblastoma multiforme (GBM) is temozolomide (TMZ) chemotherapy given concurrently with radiation for 6 weeks followed by 6 months of adjuvant TMZ."3.78Extended adjuvant temozolomide for treatment of newly diagnosed glioblastoma multiforme. ( Easaw, JC; Roldán Urgoiti, GB; Singh, AD, 2012)
"Alkylating agents, such as temozolomide (TMZ) and fotemustine (FTM) are widely used in recurrent glioblastoma (GBM) regimes."3.78Twice-daily dosing of temozolomide in combination with fotemustine for the treatment of patients with refractory glioblastoma. ( Burattini, L; Cascinu, S; Onofri, A; Paccapelo, A; Santoni, M, 2012)
"Cox regressions for survival with 314,635 inherited autosomal single-nucleotide polymorphisms (SNP) among 315 San Francisco Adult Glioma Study patients for discovery and three independent validation data sets [87 Mayo Clinic, 232 glioma patients recruited from several medical centers in Southeastern United States (GliomaSE), and 115 The Cancer Genome Atlas patients] were used to identify SNPs associated with overall survival for Caucasian glioblastoma patients treated with the current standard of care, resection, radiation, and temozolomide (total n = 749)."3.78SSBP2 variants are associated with survival in glioblastoma patients. ( Berger, MS; Brem, S; Browning, JE; Buckner, JC; Chang, SM; Decker, PA; Egan, KM; Fridley, BL; Hansen, HM; Jenkins, RB; Kosel, ML; Lachance, DH; Madden, MH; McCoy, LS; Nabors, LB; O'Neill, BP; Olson, JJ; Patoka, JS; Prados, MD; Rice, T; Smirnov, I; Thompson, RC; Tihan, T; Wiemels, JL; Wiencke, JK; Wrensch, MR; Xiao, Y, 2012)
"Polysorbate 80 coated temozolomide-loaded PLGA-based superparamagnetic nanoparticles (P80-TMZ/SPIO-NPs) were successfully synthesized and characterized as drug carriers and diagnosis agent for malignant brain glioma."3.78Temozolomide loaded PLGA-based superparamagnetic nanoparticles for magnetic resonance imaging and treatment of malignant glioma. ( Ling, Y; Wei, K; Zhong, S; Zou, F, 2012)
"The DNA alkylating agent temozolomide (TMZ) is widely used in the treatment of human malignancies such as glioma and melanoma."3.78Rational incorporation of selenium into temozolomide elicits superior antitumor activity associated with both apoptotic and autophagic cell death. ( Amin, S; Cheng, Y; Huber-Keener, KJ; Liao, J; Ren, X; Sharma, AK; Sk, UH; Sun, YW; Yang, JM; Zhang, L; Zhang, Y, 2012)
"Interferon-beta (IFN-β) is reported to augment anti-tumor effects by temozolomide in glioblastoma via down-regulation of MGMT."3.78Up-regulation of endogenous PML induced by a combination of interferon-beta and temozolomide enhances p73/YAP-mediated apoptosis in glioblastoma. ( Hara, K; Kageji, T; Kitazato, KT; Kuwayama, K; Matsuzaki, K; Mizobuchi, Y; Morigaki, R; Mure, H; Nagahiro, S; Okazaki, T, 2012)
"The effectiveness of temozolomide (TMZ) dosing schemes and the "rechallenge" of recurrent glioblastoma (GBM) with TMZ are controversial."3.78Efficacy of clinically relevant temozolomide dosing schemes in glioblastoma cancer stem cell lines. ( Beier, CP; Beier, D; Brawanski, K; Hau, P; Schriefer, B; Schulz, JB; Weis, J, 2012)
"Temozolomide (TMZ) is an alkylating chemotherapeutic agent that prolongs the survival of patients with glioblastoma."3.78Distinct molecular mechanisms of acquired resistance to temozolomide in glioblastoma cells. ( Florea, AM; Happold, C; Reifenberger, G; Roth, P; Schmidt, N; Silginer, M; Weller, M; Wick, W, 2012)
"Genome-wide microRNA (miRNA) profiling of 82 glioblastomas demonstrated that miR-181d was inversely associated with patient overall survival after correcting for age, Karnofsky performance status, extent of resection, and temozolomide (TMZ) treatment."3.78miR-181d: a predictive glioblastoma biomarker that downregulates MGMT expression. ( Chen, CC; Hoadley, K; Jiang, C; Jiang, T; Kang, C; Kushwaha, D; Li, S; Ramakrishnan, V; Song, SW; You, Y; Zhang, J; Zhang, W, 2012)
"We analyzed the usefulness of initial or recurrent treatment of temozolomide (TMZ) in pediatric high-grade gliomas (HGGs)."3.78Prognosis of pediatric high-grade gliomas with temozolomide treatment: a retrospective, multicenter study. ( Baek, HJ; Choi, HS; Jung, TY; Kim, CY; Kim, DS; Kim, IA; Kim, SH; Ra, YS, 2012)
" In this study, we show that high expression of the α5 integrin subunit compromises temozolomide-induced tumor suppressor p53 activity in human glioblastoma cells."3.78Integrin α5β1 plays a critical role in resistance to temozolomide by interfering with the p53 pathway in high-grade glioma. ( Bossert, C; Chastagner, P; Dontenwill, M; Entz-Werle, N; Godet, J; Guenot, D; Guerin, E; Janouskova, H; Leger, DY; Lehmann-Che, J; Maglott, A; Martin, S; Noulet, F; Pinel, S; Plenat, F; Teisinger, J, 2012)
"Radiotherapy plus concomitant and adjuvant temozolomide (RCAT) is now standard treatment for grade IV glioblastoma (GBM)."3.78Change in platelet levels during radiotherapy with concurrent and adjuvant temozolomide for the treatment of glioblastoma: a novel prognostic factor for survival. ( Hargreaves, S; Kooner, I; Liu, ZW; Menashy, R; Michalarea, V; Williams, M; Wilson, E; Woolf, D, 2012)
"The combination of hyperbaric oxygen with temozolomide produced an important reduction in glioma growth and effective approach to the treatment of glioblastoma."3.78Combination hyperbaric oxygen and temozolomide therapy in C6 rat glioma model. ( Bilir, A; Bozkurt, ER; Dagıstan, Y; Karaca, I; Ozar, E; Toklu, A; Yagmurlu, K, 2012)
"Temozolomide (TMZ) has become a key therapeutic agent in patients with malignant gliomas; however, its survival benefit remains unsatisfactory."3.78Valproic acid downregulates the expression of MGMT and sensitizes temozolomide-resistant glioma cells. ( Hou, Y; Jeong, CH; Jeun, SS; Kim, SM; Lim, JY; Park, KY; Ryu, CH; Woo, JS; Yoon, WS, 2012)
"Temozolomide (TMZ) is standard chemotherapy for glioblastoma multiforme (GBM)."3.78Hyperoxia resensitizes chemoresistant human glioblastoma cells to temozolomide. ( Fung, CF; Lee, D; Lee, NP; Leung, GK; Lui, WM; Pu, JK; Sun, S; Wong, ST, 2012)
"Outcomes for patients with glioblastoma have improved with the addition of temozolomide (TMZ) chemotherapy to radiation therapy followed by adjuvant TMZ for up to 1 year."3.78Helping patients make the best decision regarding duration of temozolomide chemotherapy treatment. ( Groves, MD; Plummer, AB, 2012)
"Currently, treatment of malignant gliomas with temozolomide in addition to surgical resection and radiotherapy remains the foundation of glioma therapy."3.78Local delivery of slow-releasing temozolomide microspheres inhibits intracranial xenograft glioma growth. ( Chen, Y; Cui, B; Dai, X; Dong, J; Huang, Q; Lan, Q; Tang, D; Zhang, J; Zhou, G, 2012)
"The effect of temozolomide (TMZ) and radiotherapy (RT) in the treatment of glioblastoma multiforme (GBM) has been well documented in randomized controlled trials."3.78A population-based study on the effect of temozolomide in the treatment of glioblastoma multiforme. ( Helseth, E; Johannesen, TB; Meling, TR; Rønning, PA, 2012)
"Few studies have assessed the presentation, management, and outcome of anaplastic astrocytoma (AA) in elderly patients in the temozolomide era."3.78Presentation, management, and outcome of elderly patients with newly-diagnosed anaplastic astrocytoma. ( Buckner, JC; Meyer, FB; Parney, IF; Tanaka, S; Uhm, JH; Yan, ES, 2012)
"Temozolomide (TMZ) is an oral alkylating agent widely used in the treatment of refractory glioma."3.78The synergistic therapeutic effect of temozolomide and hyperbaric oxygen on glioma U251 cell lines is accompanied by alterations in vascular endothelial growth factor and multidrug resistance-associated protein-1 levels. ( Cao, K; Li, QY; Lu, PS; Lu, XY; Yuan, ZC, 2012)
" Recently, in a phase II trial in Brazil for the treatment of temozolomide (TMZ)-resistant malignant gliomas, POH was well tolerated when administered intranasally."3.78Perillyl alcohol for the treatment of temozolomide-resistant gliomas. ( Chen, TC; Cho, HY; Goldkorn, A; Hofman, FM; Jhaveri, N; Lee, DJ; Leong, MN; Louie, SG; Petasis, NA; Schönthal, AH; Torres, S; Tseng, J; Wang, W; Xu, T, 2012)
"We have investigated on the potentiation of etoposide (ETP) and temozolomide (TMZ) cytotoxicity in U-87MG glioblastoma and D283 medulloblastoma cell lines by curcumin (CUR) and turmeric force (TF), a nutraceutical formulation of turmeric, with the objective of assessing the potential for their adjuvant use in brain tumor chemotherapy."3.78Potentiation of etoposide and temozolomide cytotoxicity by curcumin and turmeric force™ in brain tumor cell lines. ( Escalon, E; Melnick, SJ; Nair, SM; Ramachandran, C, 2012)
" Concurrent temozolomide (TMZ) improves survival in non-elderly patients with glioblastoma treated with standard schedule of 60 Gy in 30 fractions."3.78Abbreviated course of radiation therapy with concurrent temozolomide for high-grade glioma in patients of advanced age or poor functional status. ( Beal, K; Chan, TA; Gutin, PH; Lassman, AB; Reyngold, M; Yamada, Y, 2012)
"To test the effect of starvation on glioma cells in vitro, we treated primary mouse glia, murine GL26, rat C6 and human U251, LN229 and A172 glioma cells with Temozolomide in ad lib and STS mimicking conditions."3.78Fasting enhances the response of glioma to chemo- and radiotherapy. ( Brandhorst, S; Chen, TC; Conti, PS; Hwang, S; Lee, C; Longo, VD; Safdie, F; Wang, W; Wei, M, 2012)
"Treatment of patients with glioblastoma improved dramatically when concomitant and adjuvant temozolomide was added to external radiation therapy."3.78A review of dose-dense temozolomide alone and in combination with bevacizumab in patients with first relapse of glioblastoma. ( Bergqvist, M; Bergström, S; Blomquist, E; Ekman, S; Henriksson, R; Johansson, F, 2012)
"Implementation of chemotherapy with the drug temozolomide increased the overall survival of patients with glioblastoma multiforme (GBM; WHO grade IV), in particular when the O(6)-methylguanine DNA methyltransferase (MGMT) promoter is epigenetically silenced."3.78Aldehyde dehydrogenase 1A1--a new mediator of resistance to temozolomide in glioblastoma. ( Beier, CP; Bettstetter, M; Gempt, J; Hoepner, I; Koeritzer, J; Meyer, B; Rasper, M; Ringel, F; Schäfer, A; Schlegel, J; Schmidt-Graf, F; Teufel, J, 2012)
"Implantable and poly (d,l-lactide-co-glycolide) (PLGA) microparticles were developed to deliver temozolomide (TM) continuously in interstitial chemotherapy for glioma."3.77Temozolomide/PLGA microparticles: a new protocol for treatment of glioma in rats. ( Liu, JM; Yue, ZJ; Zhang, H; Zhang, YH, 2011)
"We analyzed 62 consecutive patients with newly diagnosed glioblastoma treated between 2006 and 2008 with standard fractionation to a total dose of 60 Gy with concurrent temozolomide (97%) or arsenic trioxide (3%)."3.77Pattern of failure after limited margin radiotherapy and temozolomide for glioblastoma. ( Crocker, IR; Curran, WJ; McDonald, MW; Shu, HK, 2011)
"We investigated pseudoprogression (psPD) in patients with malignant gliomas treated with radiotherapy (RT) and maintenance temozolomide (TMZ) in terms of incidence, outcomes, and predictive and prognostic factors."3.77Pseudoprogression in patients with malignant gliomas treated with concurrent temozolomide and radiotherapy: potential role of p53. ( Choe, GY; Han, JH; Kang, HC; Kim, CY; Kim, IA; Kim, JH, 2011)
"To evaluate the safety and efficacy of hypofractionated radiotherapy (RT) with a standard temozolomide (TMZ) regimen for adults with newly diagnosed glioblastoma multiforme (GBM), twenty-six consecutive adults (range 39-79 years) who met our enrollment criteria received short courses of hypofractionated RT (45 Gy in 15 fractions over three weeks) with concomitant TMZ at 75 mg/m(2)/d."3.77A pilot study of hypofractionated radiation therapy with temozolomide for adults with glioblastoma multiforme. ( Eto, T; Nakashima, S; Ogo, E; Okada, Y; Shigemori, M; Sugita, Y; Terasaki, M; Tokutomi, T, 2011)
" A 56-year-old man with a left parietal glioblastoma was treated with resection, radiation and concomitant and adjuvant temozolomide chemotherapy."3.77Kitten-transmitted Bordetella bronchiseptica infection in a patient receiving temozolomide for glioblastoma. ( Grommes, C; Papanicolaou, G; Redelman-Sidi, G, 2011)
"Temozolomide in combination with radiation has been in use for more than 5 years for the therapy of glioblastoma."3.77Hepatic encephalopathy after treatment with temozolomide. ( Goldbecker, A; Herrmann, J; Raab, P; Tryc, AB; Weissenborn, K; Worthmann, H, 2011)
"Temozolomide (TMZ) is an oral alkylating agent with proven antitumoral activity in preclinical and clinical studies in adults with high-grade glioma (HGG)."3.77Feasibility study of 21-day-on/7-day-off temozolomide in children with brain tumors. ( Barone, G; Lazzareschi, I; Riccardi, R; Ridola, V; Rizzo, D; Ruggiero, A, 2011)
" Whether MGMT promoter methylation correlates with tumor response to temozolomide in low-grade gliomas is less clear."3.77Quantitative analysis of O6-methylguanine DNA methyltransferase (MGMT) promoter methylation in patients with low-grade gliomas. ( Mariani, L; Ochsenbein, AF; Schubert, AD; Vassella, E, 2011)
"Patients with non-resectable glioblastoma generally exhibit a poor prognosis, even after radiotherapy plus concomitant and adjuvant temozolomide (XRT/TMZ→TMZ)."3.77Predominant influence of MGMT methylation in non-resectable glioblastoma after radiotherapy plus temozolomide. ( Belka, C; Eigenbrod, S; Grasbon-Frodl, EM; Kreth, FW; Kreth, S; Kretzschmar, HA; Lutz, J; Popperl, G; Thon, N; Tonn, JC, 2011)
"This prospective study was performed to determine the efficacy, safety, and tolerability of concurrent chemoradiotherapy (CCRT) followed by adjuvant chemotherapy with temozolomide (TMZ) in the treatment of patients with WHO grade III gliomas."3.77Temozolomide during and after radiation therapy for WHO grade III gliomas: preliminary report of a prospective multicenter study. ( Bae, SH; Cha, SH; Cho, WH; Choe, G; Jung, HW; Kim, CY; Kim, DG; Kim, IA; Kim, IH; Kim, YH; Lee, MM; Moon, S; Park, CK; Park, SH, 2011)
"The aim of this paper is to evaluate the efficacy of fractionated stereotactic radiotherapy (FSRT) and concomitant temozolomide (TMZ) as a salvage treatment option in patients with recurrent glioblastoma (GBM)."3.77Fractionated stereotactic reirradiation and concurrent temozolomide in patients with recurrent glioblastoma. ( Armosini, V; Caporello, P; Lanzetta, G; Maurizi, RE; Mei, M; Minniti, G; Osti, MF; Salvati, M, 2011)
"Only a few studies examined the effect of temozolomide (TMZ) in recurrent low-grade astrocytoma (LGA) after surgery, none of which included a homogeneous and sufficiently sized group of patients with progression after radiotherapy (RT)."3.77First-line temozolomide chemotherapy in progressive low-grade astrocytomas after radiotherapy: molecular characteristics in relation to response. ( Boogerd, W; Bromberg, JE; Dinjens, WN; Dubbink, HJ; Gijtenbeek, JM; Groenendijk, FH; Kouwenhoven, MC; Kros, JM; Postma, TJ; Sillevis Smitt, PA; Taal, W; van den Bent, MJ; van der Holt, B; van Heuvel, I; van Marion, R; Zonnenberg, BA; Zonnenberg, CB, 2011)
"The alkylating agent temozolomide, in combination with surgery and radiation, is the current standard of care for patients with glioblastoma."3.77Green tea epigallocatechin gallate enhances therapeutic efficacy of temozolomide in orthotopic mouse glioblastoma models. ( Chen, TC; Golden, EB; Hofman, FM; Louie, SG; Schönthal, AH; Sivakumar, W; Thomas, S; Wang, W, 2011)
" Induction of autophagy by temozolomide (TMZ) has been noted in glioma cell lines."3.77Induction of autophagy in temozolomide treated malignant gliomas. ( Aoki, H; Fujii, Y; Kakita, A; Miyahara, H; Natsumeda, M; Takahashi, H; Toyoshima, Y; Uzuka, T; Yajima, N, 2011)
"Concomitant radiation therapy (RT) and temozolomide (TMZ) therapy after surgery is the standard treatment for glioblastoma multiforme (GBM)."3.77Immune modulation effects of concomitant temozolomide and radiation therapy on peripheral blood mononuclear cells in patients with glioblastoma multiforme. ( Côté, AL; Ernstoff, MS; Fadul, CE; Fisher, JL; Gui, J; Hampton, TH, 2011)
"We analyzed prospectively whether MGMT (O(6)-methylguanine-DNA methyltransferase) mRNA expression gains prognostic/predictive impact independent of MGMT promoter methylation in malignant glioma patients undergoing radiotherapy with concomitant and adjuvant temozolomide or temozolomide alone."3.77O-methylguanine-DNA methyltransferase (MGMT) mRNA expression predicts outcome in malignant glioma independent of MGMT promoter methylation. ( Egensperger, R; Eigenbrod, S; Hinske, LC; Kreth, FW; Kreth, S; Kretzschmar, HA; Ledderose, C; Lutz, J; Thon, N; Tonn, JC, 2011)
"Temozolomide (TMZ) is the preferred chemotherapeutic agent in the treatment of glioma following surgical resection and/or radiation."3.77N-methylpurine DNA glycosylase and DNA polymerase beta modulate BER inhibitor potentiation of glioma cells to temozolomide. ( Banze, LA; Brown, AR; Goellner, EM; Hamilton, RL; Moore, B; Sobol, RW; Svilar, D; Tang, JB; Trivedi, RN; Wang, XH, 2011)
" Corticorelin acetate (Xerecept) or human corticotrophin-releasing factor (hCRF) is a comparatively new drug and has been evaluated in two orthotopic glioma models (U87 and C6), by a direct comparison with dexamethasone and temozolomide."3.77Comparison of corticotropin-releasing factor, dexamethasone, and temozolomide: treatment efficacy and toxicity in U87 and C6 intracranial gliomas. ( Blasberg, RG; de Stanchina, E; Gamez, I; Huang, R; Kochetkov, T; Moroz, MA; Ryan, RP; Shi, W; Thaler, H, 2011)
"We investigated the molecular mechanisms underlying the cytotoxic effect of Temozolomide (TMZ) in both O(6)-methylguanine-DNA methyl transferase (MGMT) depleted as well as undepleted glioblastoma cell lines."3.77Temozolomide induced c-Myc-mediated apoptosis via Akt signalling in MGMT expressing glioblastoma cells. ( Brunetti, E; Bucci, B; D'agnano, I; De Paula, U; De Salvo, M; Gagliassi, R; Marchese, R; Maresca, G; Raza, GH; Stigliano, A, 2011)
"To study the impact of two human glioma tissue resistance genes MGMT and ERCC(2) on the temozolomide-based treatment of malignant gliomas and detect the relationship of their expressions."3.77[Comparison of MGMT and ERCC₂ expression in temozolomide for the treatment of malignant glioma drug resistance and their genetic relationship]. ( Hou, X; Sun, JH; Wang, JJ; Wu, ZC; Zhao, Y; Zheng, YR, 2011)
"Epigenetic silencing of the O(6) -methylguanine-DNA methyltransferase (MGMT) gene promoter is associated with prolonged survival in glioblastoma patients treated with temozolomide (TMZ)."3.77Promoter methylation and expression of MGMT and the DNA mismatch repair genes MLH1, MSH2, MSH6 and PMS2 in paired primary and recurrent glioblastomas. ( Eigenbrod, S; Felsberg, J; Hentschel, B; Kreth, FW; Löffler, M; Pietsch, T; Reifenberger, G; Sabel, MC; Schackert, G; Thon, N; Tonn, JC; Weller, M; Westphal, M, 2011)
"Temozolomide has significantly improved the outcome of patients with glioblastoma."3.77[Benefit of a prolonged adjuvant treatment with temozolomide for the management of patients with glioblastoma]. ( Auberdiac, P; Cartier, L; Chargari, C; Forest, F; Fotso, MJ; Magné, N; Malkoun, N; Nuti, C; Pacaut, C; Peoc'h, M; Schmitt, T; Thorin, J, 2011)
"Temozolomide (TMZ), an alkylating agent widely used for patients with glioblastoma multiforme (GBM), has the potential to enhance the acquired immune response to GBM."3.77Pathological changes after autologous formalin-fixed tumor vaccine therapy combined with temozolomide for glioblastoma - three case reports - . ( Enomoto, T; Ishikawa, E; Matsumura, A; Morishita, Y; Nakai, K; Ohno, T; Sakamoto, N; Sato, M; Satomi, K; Takano, S; Tsuboi, K; Yamamoto, T, 2011)
"5 years, ranging from 25-82 years, 19 female and 29 male) with histologically proven glioblastoma received surgery (16 biopsies, 18 partial and 14 complete resections) and postoperative chemo-irradiation with concomitant and adjuvant temozolomide."3.77Overall survival and extent of surgery in adult versus elderly glioblastoma patients: A population based retrospective study. ( Cejna, M; DeVries, A; Eiter, H; Maier, R; Muxel, B; Muxel, M; Roessler, K; Zachenhofer, I, 2011)
"To demonstrate the feasibility of using DNP hyperpolarized [1-(13)C]-pyruvate to measure early response to temozolomide (TMZ) therapy using an orthotopic human glioblastoma xenograft model."3.77Detection of early response to temozolomide treatment in brain tumors using hyperpolarized 13C MR metabolic imaging. ( Bok, R; James, CD; Nelson, SJ; Ozawa, T; Park, I; Phillips, JJ; Ronen, SM; Vigneron, DB, 2011)
"This study was designed to evaluate proton magnetic resonance spectroscopy ((1)H-MRS) for monitoring the WHO grade II glioma (low-grade glioma (LGG)) treated with temozolomide (TMZ)."3.77Predicting the outcome of grade II glioma treated with temozolomide using proton magnetic resonance spectroscopy. ( Abud, L; Capelle, L; Chiras, J; Costalat, R; De Marco, G; Guillevin, R; Habas, C; Hoang-Xuan, K; Menuel, C; Taillibert, S; Vallée, JN, 2011)
"It is controversial if distant recurrence of glioblastoma is more common after temozolomide (TMZ) concurrent with radiotherapy (RT)."3.77Glioblastoma: patterns of recurrence and efficacy of salvage treatments. ( Aviv, R; Davey, P; Lam, K; Oh, J; Perry, JR; Sahgal, A; Sanghera, P; Symons, S; Tsao, MN, 2011)
" In vitro Southern Blot analysis and cytopathic effect assays demonstrate high anti-glioma potency, which was significantly increased in combination with temozolomide (TMZ), daunorubicin and cisplatin."3.77YB-1 dependent virotherapy in combination with temozolomide as a multimodal therapy approach to eradicate malignant glioma. ( Anton, M; Gänsbacher, B; Haczek, C; Holm, PS; Holzmüller, R; Kasajima, A; Lage, H; Mantwill, K; Rognoni, E; Schlegel, J; Schuster, T; Treue, D; Weichert, W, 2011)
"We tested the use of the small-molecule Inhibitor of Apoptosis Protein (IAP) inhibitor LBW242 in combination with the standard-of-care therapies of irradiation and temozolomide for malignant gliomas."3.77A small-molecule IAP inhibitor overcomes resistance to cytotoxic therapies in malignant gliomas in vitro and in vivo. ( Barnes, J; Fast, EM; Keating, J; Kesari, S; Kieran, MW; Kung, AL; Ramakrishna, N; Veldhuijzen van Zanten, SE; Zawel, L; Ziegler, DS, 2011)
"Patients with high-grade gliomas (HGG) routinely receive radiation, temozolomide, and glucocorticoids."3.77Immunosuppression in patients with high-grade gliomas treated with radiation and temozolomide. ( Carraway, H; Desideri, S; Grossman, SA; Lesser, G; Piantadosi, S; Sloan, A; Ye, X, 2011)
"Promoter methylation of the O⁶-methylguanine-DNA-methyltransferase (MGMT) gene is widely recognized as an important predictive factor in the treatment of glioblastoma (GBM) patients with temozolomide."3.77MGMT promoter gene methylation in pediatric glioblastoma: analysis using MS-MLPA. ( Cho, BK; Kim, SK; Lee, JY; Park, CK; Park, SH; Wang, KC, 2011)
"Temozolomide (TMZ) is an alkylating agent that has yielded significant benefits and is a current standard agent in the treatment of malignant gliomas."3.77Gene expression profiles predicting the response to IFN-β and a combination of temozolomide and IFN-β in malignant gliomas. ( Fukushima, T; Katayama, Y; Ogino, A; Ohta, T; Okamoto, Y; Sano, E; Tashiro, S; Tsumoto, K; Watanabe, T; Yachi, K; Yoshino, A, 2011)
"The goal of this study was to evaluate accelerated radiotherapy with and without temozolomide (TMZ) for glioblastoma multiforme (GBM)."3.77Prolonged survival when temozolomide is added to accelerated radiotherapy for glioblastoma multiforme. ( Buttmann, M; Flentje, M; Guckenberger, M; Mayer, M; Sweeney, RA; Vince, GH, 2011)
"A group of 160 patients with primary glioblastoma treated with radiotherapy and temozolomide was analyzed for the impact of O6-methly-guanly-methyl-transferase (MGMT)-promoter methylation as well as isocitrate dehydrogenase (IDH)1-mutational status."3.77Prognostic significance of IDH-1 and MGMT in patients with glioblastoma: one step forward, and one step back? ( Abdollahi, A; Combs, SE; Debus, J; Hartmann, C; Rieken, S; von Deimling, A; Wick, W, 2011)
" Treatment of glioblastoma multiforme (GBM) with temozolomide (TMZ), its current standard of care, is problematic because the tumor generally recurs and is then resistant to this drug."3.77Noscapine inhibits tumor growth in TMZ-resistant gliomas. ( Chen, TC; Cho, H; Hofman, FM; Jhaveri, N; Louie, SG; Petasis, NA; Schönthal, AH; Torres, S; Wang, W, 2011)
"A 61-year-old man with glioblastoma and positive for hepatitis B surface antigen (HBsAg) developed acute hepatitis due to hepatitis B virus (HBV) reactivation after concomitant postoperative treatment with temozolomide (75 mg/m(2)/day) and radiation therapy (60 Gy in 30 fractions)."3.77Reactivation of hepatitis B virus after glioblastoma treatment with temozolomide--case report. ( Kayama, T; Miyakita, Y; Narita, Y; Ohno, M; Shibui, S; Ueno, H, 2011)
"The objective of this retrospective analysis was to assess long-term outcome and prognostic factors of unselected patients treated for glioblastoma (GB) at a single center with surgery, standard radiotherapy (RT), and concomitant temozolomide (TMZ)."3.77Radiochemotherapy with temozolomide for patients with glioblastoma. Prognostic factors and long-term outcome of unselected patients from a single institution. ( Franz, K; Gerstein, J; Rödel, C; Seifert, V; Steinbach, JP; Weiss, C, 2011)
"Prolonged administration of temozolomide is widely used in patients with glioblastoma; whereas the treatment of anaplastic glioma differs between neurooncological centres."3.77Prolonged administration of temozolomide in adult patients with anaplastic glioma. ( Freyschlag, CF; Janzen, E; Lohr, F; Schmieder, K; Seiz, M; Smolczyk, DR; Thomé, C; Tuettenberg, J; Weiss, C; Wenz, F, 2011)
"A 62-year female received radiotherapy over six weeks with daily 75 mg/m2 Temozolomide (TMZ) for Glioblastoma (GB)."3.77Temozolomide induced liver injury. ( Afzal, P; Campbell, AP; Dixit, S; Hingorani, M, 2011)
"To evaluate the incidence and impact of early post-chemoradiation (cRT) 'pseudoprogression' (PsPD) amongst glioblastoma multiforme (GBM) patients treated with the current standard of care - 60 Gy conformal radiotherapy with concurrent low-dose temozolomide, followed by six cycles of high-dose temozolomide (the 'Stupp protocol')."3.77Early post-treatment pseudo-progression amongst glioblastoma multiforme patients treated with radiotherapy and temozolomide: a retrospective analysis. ( Gunjur, A; Lau, E; Ryan, G; Taouk, Y, 2011)
"To study the efficacy and safety of 3-dimensional conformal radiotherapy combined with temozolomide (TMZ) for gliomas."3.77[Efficacy and safety of 3-dimensional conformal radiotherapy combined with temozolomide for glioma]. ( Tu, Q; Wang, L; Zhou, R; Zhou, W, 2011)
" Recently, the alkylating agent temozolomide, which has demonstrated activity in patients with brain metastasis and primary tumors, was used alongside WBR to delay brain metastasis recurrence, increase survival, and improve quality-of-life in patients with brain metastases."3.77Retrospective study of patients with brain metastases from melanoma receiving concurrent whole-brain radiation and temozolomide. ( Chen, R; Devito, N; Pan, E; Yu, M, 2011)
"The aim of this study was to evaluate cognitive functioning in newly-diagnosed glioblastoma multiforme (GBM) patients during treatment with radiotherapy (RT) plus concomitant and adjuvant temozolomide (TMZ)."3.76Cognitive functioning in glioblastoma patients during radiotherapy and temozolomide treatment: initial findings. ( Bosma, I; Buter, J; Heimans, JJ; Hilverda, K; Klein, M; Peter Vandertop, W; Postma, TJ; Reijneveld, JC; Slotman, BJ, 2010)
"Concomitant daily temozolomide and radiation followed by adjuvant temozolomide is a tolerable and reasonable treatment option and has a good performance status for elderly patients diagnosed with glioblastoma."3.76Concurrent temozolomide and radiation, a reasonable option for elderly patients with glioblastoma multiforme? ( Collichio, F; Ewend, MG; Grabowski, S; Kimple, RJ; Morris, DE; Papez, M, 2010)
"In this study, we investigated the potential of combined treatment with temozolomide (TMZ) chemotherapy and tumor antigen-pulsed dendritic cells (DCs) and the underlying immunological factors of TMZ chemoimmunotherapy with an intracranial GL26 glioma animal model."3.76Immunological factors relating to the antitumor effect of temozolomide chemoimmunotherapy in a murine glioma model. ( Chung, DS; Hong, YK; Kim, CH; Kim, CK; Kim, TG; Park, JS; Park, SD, 2010)
"This study was performed to evaluate the addition of temozolomide (TMZ) to whole brain radiotherapy (WBRT) for brain metastases from melanoma."3.76Brain metastases from melanoma: is there a role for concurrent temozolomide in addition to whole brain radiation therapy? ( Bearden, JD; Behl, D; Brown, PD; Deming, RL; Markovic, SN; Rowland, KM; Sande, JR; Schild, SE, 2010)
"We present two patients with glioblastoma with an unusually stable clinical course and long-term survival who were treated after surgery and radiotherapy with adjuvant temozolomide (TMZ) chemotherapy for 17 and 20 cycles, respectively."3.76Patient-tailored, imaging-guided, long-term temozolomide chemotherapy in patients with glioblastoma. ( Backes, H; Brunn, A; Burghaus, L; Galldiks, N; Heiss, WD; Jacobs, AH; Kracht, LW; Ullrich, RT, 2010)
"O(6)-Methylguanine DNA methyltransferase (MGMT) is implicated as a major predictive factor for treatment response to alkylating agents including temozolomide (TMZ) of glioblastoma multiforme (GBM) patients."3.76O6-Methylguanine DNA methyltransferase protein expression in tumor cells predicts outcome of temozolomide therapy in glioblastoma patients. ( Berger, W; Buchroithner, J; Filipits, M; Fischer, J; Lötsch, D; Micksche, M; Pichler, J; Pirker, C; Silye, R; Spiegl-Kreinecker, S; Weis, S, 2010)
"Epigenetic silencing of the MGMT gene by promoter methylation is associated with loss of MGMT expression, diminished DNA-repair activity and longer overall survival in patients with glioblastoma who, in addition to radiotherapy, received alkylating chemotherapy with carmustine or temozolomide."3.76Promoter methylation analysis of O6-methylguanine-DNA methyltransferase in glioblastoma: detection by locked nucleic acid based quantitative PCR using an imprinted gene (SNURF) as a reference. ( Brandes, A; de Biase, D; Ermani, M; Franceschi, E; Marucci, G; Morandi, L; Pession, A; Tallini, G; Tosoni, A, 2010)
"Pseudoprogression (psPD) is now recognised following radiotherapy with concurrent temozolomide (RT/TMZ) for glioblastoma multiforme (GBM)."3.76Pseudoprogression following chemoradiotherapy for glioblastoma multiforme. ( Aviv, R; Davey, P; Lam, K; Morrison, M; Perry, J; Sahgal, A; Sanghera, P; Symons, S; Tsao, MN, 2010)
"We hypothesized that the observed clinical synergy of orally administered TMZ and carmustine (BCNU) wafers would translate into even greater effectiveness with the local delivery of BCNU and TMZ and the addition of radiotherapy in animal models of malignant glioma."3.76Combination of intracranial temozolomide with intracranial carmustine improves survival when compared with either treatment alone in a rodent glioma model. ( Bekelis, K; Brem, H; Li, KW; Recinos, VR; Sunshine, SB; Tyler, BM; Vellimana, A, 2010)
"To determine recurrence patterns of glioblastoma treated with temozolomide-based chemoradiation."3.76Patterns and timing of recurrence after temozolomide-based chemoradiation for glioblastoma. ( Donatello, RS; Korones, DN; Milano, MT; Mohile, NA; Okunieff, P; Sul, J; Walter, KA, 2010)
"Novel agents are currently combined with radiation and temozolomide (RT + TMZ) in newly diagnosed glioblastoma using overall survival as the primary end point."3.76Survival of patients with newly diagnosed glioblastoma treated with radiation and temozolomide in research studies in the United States. ( Desideri, S; Fisher, J; Grossman, SA; Nabors, LB; Piantadosi, S; Rosenfeld, M; Ye, X, 2010)
" We present the case of a 26-year-old male suffering a fatal ICH in the context of treatment of a high grade glioma with temozolomide."3.76Intracerebral hemorrhage secondary to thrombocytopenia in a patient treated with temozolomide. ( Anderson, WS; Dunn, I; Norden, A; Sure, D, 2010)
"A retrospective multicenter study was conducted in 26 French Departments of Neurosurgery to analyze practices of French neurosurgeons using Gliadel, compare the adverse effects and survival with those of previous phase III trials, and assess survival in patients with newly diagnosed malignant gliomas (MG) receiving Gliadel plus radiochemotherapy with temozolomide (TMZ)."3.76Biodegradable carmustine wafers (Gliadel) alone or in combination with chemoradiotherapy: the French experience. ( Capelle, L; Guyotat, J; Jacquet, G; Loiseau, H; Menei, P; Metellus, P; Parot-Schinkel, E, 2010)
"Concurrent treatment with the methylating agent temozolomide during radiotherapy has yielded the first significant improvement in the survival of adult glioblastomas (GBM) in the last three decades."3.76Minimally cytotoxic doses of temozolomide produce radiosensitization in human glioblastoma cells regardless of MGMT expression. ( Blank, A; Bobola, MS; Kolstoe, DD; Silber, JR, 2010)
"There is a growing evidence of using Temozolomide as upfront therapy for progressive low grade gliomas."3.76Nitrosourea-based chemotherapy for low grade gliomas failing initial treatment with temozolomide. ( Dehais, C; Delattre, JY; Ducray, F; Hoang-Xuan, K; Houillier, C; Idbaih, A; Kaloshi, G; Laigle-Donadey, F; Omuro, A; Psimaras, D; Sanson, M; Sierra del Rio, M; Taillibert, S, 2010)
"The purpose of this study was to evaluate diffusion parameters at pre-, mid-, and post-radiation therapy (RT) in contrast-enhancing and nonenhancing lesions of postsurgical glioblastoma multiforme patients treated with the standard of care RT concurrently with temozolomide (TMZ) followed by adjuvant TMZ and an antiangiogenic drug."3.76Evaluation of diffusion parameters as early biomarkers of disease progression in glioblastoma multiforme. ( Butowski, NA; Cha, S; Chang, SM; Elkhaled, A; Jalbert, L; Khayal, IS; Nelson, SJ; Polley, MY, 2010)
"To evaluate perfusion parameter changes in patients with glioblastoma multiforme by comparing the perfusion magnetic resonance (MR) imaging measurements obtained before combined radiation and temozolomide therapy (RT-TMZ) with the follow-up MR imaging measurements obtained 1 month after completion of this treatment."3.76Changes in relative cerebral blood volume 1 month after radiation-temozolomide therapy can help predict overall survival in patients with glioblastoma. ( Ekholm, SE; Korones, DN; Mangla, R; Milano, MT; Singh, G; Zhong, J; Ziegelitz, D, 2010)
"Temozolomide, an oral alkylating agent, is a commonly used medicine in the treatment of anaplastic astrocytoma and glioblastoma multiforme."3.76Temozolomide (Temodar). ( Mukherji, SK; Rajdev, P; Wesolowski, JR, 2010)
"Temozolomide is the major drug in the treatment of malignant gliomas."3.76Radiation induced early necrosis in patients with malignant gliomas receiving temozolomide. ( Akmansu, M; Benekli, M; Buyukberber, S; Coskun, U; Kaya, AO; Oner, Y; Ozturk, B; Uncu, D; Yaman, E; Yildiz, R, 2010)
"O(6)-methylguanine-DNA methyltransferase (MGMT) expression in glioblastoma correlates with temozolomide resistance."3.76Effect of alternative temozolomide schedules on glioblastoma O(6)-methylguanine-DNA methyltransferase activity and survival. ( Donze, J; Liu, L; McGraw, M; Palomo, JM; Rahmathulla, G; Robinson, CG; Vogelbaum, MA, 2010)
"The aim of the present study was to investigate the effect of Temozolomide (an alkylating chemotherapeutic agent) and quercetin (natural flavonoid) on cell death in the human astrocytoma cell line MOGGCCM (WHO grade III)."3.76Temozolomide, quercetin and cell death in the MOGGCCM astrocytoma cell line. ( Jakubowicz-Gil, J; Langner, E; Piersiak, T; Rzeski, W; Wertel, I, 2010)
"We present a case of a 12-year-old female with a germline TP53 mutation who presented with anaplastic astrocytoma and subsequent acute lymphoblastic leukemia (ALL) 13 months after starting treatment with temozolomide (TMZ)."3.76Acute lymphoblastic leukemia after temozolomide treatment for anaplastic astrocytoma in a child with a germline TP53 mutation. ( Hosono, A; Makimoto, A; Miyakita, Y; Momota, H; Nariata, Y; Narita, Y; Shibui, S, 2010)
" We have compiled the treatment experience of seven neurosurgical centers using implantation of carmustine wafers at primary surgery followed by 6 weeks of radiation therapy (59-60 Gy) and 75 mg/m(2)/day TMZ in patients with newly diagnosed glioblastoma followed by TMZ monochemotherapy."3.76First-line treatment of malignant glioma with carmustine implants followed by concomitant radiochemotherapy: a multicenter experience. ( Bock, HC; Buchalla, R; Giese, A; Kantelhardt, SR; Ketter, R; Koll, S; Lohmann, F; Puchner, MJ; Rainov, N; Rohde, V; Schütze, M, 2010)
"Standard treatment of glioblastoma multiforme consists of postoperative radiochemotherapy with temozolomide, followed by a 6-month chemotherapy."3.76Aplastic anemia as a cause of death in a patient with glioblastoma multiforme treated with temozolomide. ( Kopecký, J; Kopecký, O; Macingova, Z; Petera, J; Priester, P; Slovácek, L, 2010)
"Malignant glioma patients treated with the golden standard therapy, focal radiotherapy plus concomitant daily temozolomide (radiotherapy/TMZ), often suffer severe lymphopenia."3.76Low peripheral lymphocyte count before focal radiotherapy plus concomitant temozolomide predicts severe lymphopenia during malignant glioma treatment. ( Akutsu, H; Ishikawa, E; Matsumura, A; Nakai, K; Sakamoto, N; Takano, S; Tsuboi, K; Yamamoto, T, 2010)
"Temozolomide (TM) has anti-tumor activity in patients with malignant glioma."3.76Temozolomide/PLGA microparticles plus vatalanib inhibits tumor growth and angiogenesis in an orthotopic glioma model. ( Liu, JM; Tang, GS; Wang, Y; Yue, ZJ; Zhang, H; Zhang, YH, 2010)
"The addition of temozolomide (TMZ) to radiotherapy (RT) improves survival of patients with glioblastoma (GB) when compared to postoperative RT alone in patients up to 65 years of age."3.76Postoperative radiotherapy and concomitant temozolomide for elderly patients with glioblastoma. ( Franz, K; Fraunholz, I; Gerstein, J; Rödel, C; Seifert, V; Steinbach, JP; Weiss, C, 2010)
"To analyze the recurrence patterns in patients with newly diagnosed glioblastoma (GBM) treated with conformal radiotherapy (RT) plus concomitant and adjuvant temozolomide (TMZ), and to compare the patterns of failure according to different target volume delineations."3.76Patterns of failure and comparison of different target volume delineations in patients with glioblastoma treated with conformal radiotherapy plus concomitant and adjuvant temozolomide. ( Amelio, D; Amichetti, M; Arcella, A; Bozzao, A; Enrici, RM; Lanzetta, G; Minniti, G; Muni, R; Salvati, M; Scarpino, S, 2010)
"Temozolomide is an oral alkylating agent approved for the treatment of glioblastoma and anaplastic astrocytoma, and is currently under clinical investigation for the treatment of brain metastases from a variety of cancers."3.76Urticarial hypersensitivity reaction caused by temozolomide. ( Hsu, MY; Ibrahimi, OA; Kesari, S; Pothiawala, S; Yang, C, 2010)
" We assessed the ability of 17-AAG to inhibit the growth of glioma cell lines and glioma stem cells both in vitro and in vivo and assessed its ability to synergize with radiation and/or temozolomide, the standard therapies for GBM."3.75Efficacy of the HSP90 inhibitor 17-AAG in human glioma cell lines and tumorigenic glioma stem cells. ( Barnes, J; Dellagatta, J; Kesari, S; Kieran, MW; Kung, AL; Ramakrishna, NR; Sauvageot, CM; Stiles, CD; Weatherbee, JL; Wen, PY; Winters, SE, 2009)
"Some patients with glioblastoma multiform do not respond to temozolomide even though they have aberrant promoter methylation of the DNA repair enzyme O(6)-methylguanine methyltransferase (MGMT)."3.75A MDR1 (ABCB1) gene single nucleotide polymorphism predicts outcome of temozolomide treatment in glioblastoma patients. ( Dill, C; Ehninger, G; Illmer, T; Kestel, L; Kramer, M; Krex, D; Pfirrmann, M; Robel, K; Schackert, G; Schaich, M, 2009)
" In this study, we used pharmacokinetic and pharmacodynamic approaches to investigate how sunitinib at different dose levels affects brain distribution of temozolomide (TMZ), and to ascertain the relationship between intratumoral TMZ concentrations and tumor vascularity in an orthotopic human glioma model."3.75Differential effect of sunitinib on the distribution of temozolomide in an orthotopic glioma model. ( Gallo, JM; Zhou, Q, 2009)
"CpG methylation within the O6-methylguanine-DNA-methyltransferase (MGMT) promoter is associated with enhanced survival of glioblastoma multiforme (GBM) patients treated with temozolomide (TMZ)."3.75Evaluation of MGMT promoter methylation status and correlation with temozolomide response in orthotopic glioblastoma xenograft model. ( Ballman, KV; Buckner, JC; Carlson, BL; Decker, PA; Giannini, C; Grogan, PT; James, CD; Kitange, GJ; Mladek, AC; Sarkaria, JN; Schroeder, MA; Wu, W, 2009)
" In this study, we investigated whether, intravenously administered, ATP-sensitive potassium channel (K(ATP)) activator (minoxidil sulfate; MS) increases temozolomide and Herceptin delivery to brain tumors to induce anti-tumor activity and increase survival in nude mice with Glioblastoma multiforme (GBM) cells."3.75Activation of KATP channels increases anticancer drug delivery to brain tumors and survival. ( Khaitan, D; Meister, EA; Ningaraj, NS; Sankpal, UT; Vats, T, 2009)
"We report a case of a 51-year-old woman with newly diagnosed glioblastoma multiforme (GBM) who was treated with surgery followed by the standard concomitant temozolomide (TMZ) and radiotherapy (RT)."3.75Prolonged and severe thrombocytopenia with pancytopenia induced by radiation-combined temozolomide therapy in a patient with newly diagnosed glioblastoma--analysis of O6-methylguanine-DNA methyltransferase status. ( Fujioka, Y; Homori, M; Kurita, H; Miyazaki, H; Nagane, M; Nozue, K; Shimizu, S; Shiokawa, Y; Waha, A, 2009)
"Seven patients (4 men; 3 women) ages 34-69 years (median 44), with gliomas (3 Grade 2; 4 Grade 3) were treated with surgery, all but one with involved-field radiotherapy and all with alkylator-based chemotherapy (temozolomide; 6 patients, nitrosoureas; 5 patients, both agents; 5 patients)."3.75Extended exposure to alkylator chemotherapy: delayed appearance of myelodysplasia. ( Chamberlain, MC; Raizer, J, 2009)
" The observed adverse effects of temozolomide included nausea, vomiting, headache, constipation, mild marrow suppression, and decreased activity; none of them was severe enough to discontinue the treatment."3.75Efficacy of temozolomide for recurrent embryonal brain tumors in children. ( Chang, KP; Hsu, TR; Wang, CH; Wong, TT, 2009)
"Early radionecrosis after the Stupp protocol is not a rare event due to the radiosensitization effect of temozolomide."3.75Early clinical and neuroradiological worsening after radiotherapy and concomitant temozolomide in patients with glioblastoma: tumour progression or radionecrosis? ( Del Basso De Caro, ML; Elefante, A; Giamundo, A; Maiuri, F; Mariniello, G; Pacelli, R; Peca, C; Vergara, P, 2009)
" Moreover, enhanced growth delay with the addition of E7016 to temozolomide and radiotherapy in a glioma mouse model suggests a potential role for this drug in the treatment of glioblastoma multiforme."3.75In vitro and in vivo radiosensitization of glioblastoma cells by the poly (ADP-ribose) polymerase inhibitor E7016. ( Beam, K; Burgan, WE; Camphausen, K; Carter, D; Chakravarti, A; Kwon, HC; Russo, AL; Slusher, BS; Tofilon, PJ; Weizheng, X; Zhang, J, 2009)
"The aim of the present study was to evaluate factors predicting the recurrence pattern after the administration of temozolomide (TMZ), initially concurrent with radiotherapy (RT) and subsequently as maintenance therapy, which has become standard treatment for patients with newly diagnosed glioblastoma (GBM)."3.75Recurrence pattern after temozolomide concomitant with and adjuvant to radiotherapy in newly diagnosed patients with glioblastoma: correlation With MGMT promoter methylation status. ( Amistà, P; Brandes, AA; Ermani, M; Franceschi, E; Frezza, G; Morandi, L; Sotti, G; Spagnolli, F; Tosoni, A, 2009)
"Recently, there has been greater awareness that combination radiation and temozolomide used to treat glioblastomas may cause increased contrast enhancement on the first post radiation MRI scan."3.75Effect of adding temozolomide to radiation therapy on the incidence of pseudo-progression. ( Gerstner, ER; Lafrankie, D; McNamara, MB; Norden, AD; Wen, PY, 2009)
"Temozolomide (TMZ) is the standard of care for patients with newly diagnosed glioblastoma (GBM) as well as those with recurrent anaplastic glioma (AG) and GBM."3.75Rechallenge with temozolomide in patients with recurrent gliomas. ( Bogdahn, U; Hau, P; Jauch, T; Pascher, C; Weller, M; Wick, A; Wick, W, 2009)
"Temozolomide (TMZ) is an alkylating agent used in the management of gliomas."3.75Long-term use of temozolomide: could you use temozolomide safely for life in gliomas? ( Bell, D; Khasraw, M; Wheeler, H, 2009)
"We have completed in vivo safety and efficacy studies of the use of a novel drug delivery system, a gel matrix-temozolomide formulation that is injected intracranially into the post-resection cavity, as a candidate for glioma therapy."3.75Delivery of temozolomide to the tumor bed via biodegradable gel matrices in a novel model of intracranial glioma with resection. ( Akbar, U; Duntsch, C; Jones, T; Michael, M; Shukla, A; Sun, Y; Winestone, J, 2009)
"Temozolomide is considered the standard of care and drug of choice for the treatment of initially diagnosed malignant gliomas."3.75Glioma-associated endothelial cells are chemoresistant to temozolomide. ( Chen, TC; Golden, EB; Hofman, FM; Pen, L; Schönthal, AH; Sivakumar, W; Virrey, JJ; Wang, W, 2009)
"We evaluated the benefit of preradiation chemotherapy with ACNU (nimustine) and CDDP (cisplatin) in patients with newly diagnosed glioblastoma by retrospective analysis."3.75Preradiation chemotherapy with ACNU-CDDP in patients with newly diagnosed glioblastoma: a retrospective analysis. ( Han, JH; Heo, DS; Jung, HW; Kim, CY; Kim, DG; Kim, DW; Kim, IH; Lee, SH; Paek, SH; Park, CK, 2009)
"A 46-year-old man developed Stevens-Johnson syndrome and toxic epidermal necrolysis overlap, with severe localized denudation of the skin on the head and neck, following radiotherapy and oral temozolomide therapy for cranial glioblastoma multiforme."3.75Stevens-Johnson Syndrome and toxic epidermal necrolysis overlap due to oral temozolomide and cranial radiotherapy. ( Sarma, N, 2009)
" On the other hand, temozolomide (TMZ), an oral bioavailable alkylating agent with excellent tolerability, has demonstrated efficacy and has become a key therapeutic agent in patients with malignant gliomas; however, its survival benefit remains unsatisfactory."3.75Effect of IFN-beta on human glioma cell lines with temozolomide resistance. ( Fukushima, T; Katayama, Y; Naruse, N; Ogino, A; Ohta, T; Okamoto, Y; Sano, E; Watanabe, T; Yachi, K; Yoshino, A, 2009)
"A recent randomized study conducted on newly diagnosed glioblastoma (GBM) patients demonstrated that concomitant and adjuvant temozolomide added to standard radiotherapy had a survival advantage compared with radiotherapy alone."3.75Temozolomide concomitant and adjuvant to radiotherapy in elderly patients with glioblastoma: correlation with MGMT promoter methylation status. ( Agati, R; Bacci, A; Benevento, F; Brandes, AA; Calbucci, F; Ermani, M; Franceschi, E; Mazzocchi, V; Scopece, L; Tosoni, A, 2009)
"Previous studies have revealed that p38, a member of the family of stress-activated protein kinases (SAPKs), cooperates with the Chk1-pathway to bring about temozolomide (TMZ)-induced G2 arrest, and that the inhibition of either pathway alone is sufficient to sensitize U87MG glioma cells to TMZ-induced cytotoxicity."3.75Inhibition of c-Jun N-terminal kinase enhances temozolomide-induced cytotoxicity in human glioma cells. ( Hirose, Y; Kawase, T; Ohba, S; Sano, H, 2009)
"Methionine depletion causes a demonstrable increase in glutathione levels for medulloblastoma (Daoy) and glioma (D54) cells, with a decrease in MGMT activity for Daoy cells."3.75Methionine restriction reduces the chemosensitivity of central nervous system tumour cell lines. ( Estlin, EJ; McGown, A; Najim, N; Podmore, ID, 2009)
"Concurrent temozolomide (TMZ) and radiation therapy (RT) followed by adjuvant TMZ is standard treatment for patients with glioblastoma multiforme (GBM), although the relative contribution of concurrent versus adjuvant TMZ is unknown."3.75Radiosensitizing effects of temozolomide observed in vivo only in a subset of O6-methylguanine-DNA methyltransferase methylated glioblastoma multiforme xenografts. ( Ballman, KA; Carlson, BL; Decker, PA; Giannini, C; Grogan, PT; James, CD; Kitange, GJ; Mladek, AC; Sarkaria, JN; Schroeder, MA; Wu, W, 2009)
" For example, Temozolomide (TMZ) exhibits some antitumor activity against brain tumors, so does Trastuzumab (Herceptin, Her-2 inhibitor), which might be effective against Her2 neu overexpressing gliomas."3.75Modulation of KCa channels increases anticancer drug delivery to brain tumors and prolongs survival in xenograft model. ( Khaitan, D; Meister, EA; Ningaraj, NS; Sankpal, UT; Vats, TS, 2009)
"Eighty-three patients with glioblastoma underwent surgery followed by radiotherapy and temozolomide chemotherapy between October 2000 and June 2008."3.75The correlation and prognostic significance of MGMT promoter methylation and MGMT protein in glioblastomas. ( Cao, VT; Chae, HJ; Jin, SG; Jung, S; Jung, TY; Kang, SS; Kim, IY; Lee, KH; Moon, KS; Park, CS, 2009)
"Our data suggest that temozolomide is an active regimen for malignant gliomas."3.74Temozolomide in newly diagnosed malignant gliomas: administered concomitantly with radiotherapy, and thereafter as consolidation treatment. ( Akmansu, M; Benekli, M; Buyukberber, S; Coskun, U; Gunel, N; Kaya, AO; Ozkan, S; Ozturk, B; Uner, A; Yamac, D; Yaman, E; Yildiz, R, 2008)
"Although high AGT levels may mediate resistance in a portion of these samples, MMR deficiency does not seem to be responsible for mediating temozolomide resistance in adult malignant glioma."3.74Mismatch repair deficiency does not mediate clinical resistance to temozolomide in malignant glioma. ( Ali-Osman, F; Bigner, DD; Friedman, AH; Friedman, HS; Horne, KS; Johnson, SP; Lister, DW; Maxwell, JA; McLendon, RE; Modrich, PL; Quinn, JA; Rasheed, A, 2008)
" Convection-enhanced delivery (CED) of either the replication-defective, ICP0-producing HSV-1 mutant, d106, or the recombinant d109, devoid of all viral genome expression, was performed to determine the in vivo efficacy of ICP0 in combination with ionizing radiation (IR) or systemic temozolomide (TMZ) in the treatment of glioblastoma multiforme (GBM)."3.74Therapeutic efficacy of a herpes simplex virus with radiation or temozolomide for intracranial glioblastoma after convection-enhanced delivery. ( Deluca, NA; Fellows-Mayle, W; Hadjipanayis, CG, 2008)
"Use of antiangiogenic therapy with radiation and temozolomide in the primary management of high-grade glioma is feasible."3.74Feasibility of using bevacizumab with radiation therapy and temozolomide in newly diagnosed high-grade glioma. ( Eagan, P; Fischer, I; Golfinos, JG; Gruber, ML; Kelly, P; Knopp, EA; Medabalmi, P; Narayana, A; Parker, E; Raza, S; Zagzag, D, 2008)
"Temozolomide is an alkylating agent approved for treatment of glioblastoma in association with radiotherapy."3.74[Alveolo-interstitial pneumonia due to Temozolamide]. ( Autret-Leca, E; Beau Salinas, F; Carré, P; de Luca, K; Diot, P; Guilleminault, L; Narciso, B, 2008)
" In this study, the authors investigate the nature of the SP phenotype in 2 glioma cell lines, U87MG and T98G, and their response to temozolomide."3.74Characterization of a side population of astrocytoma cells in response to temozolomide. ( Ang, BT; Chong, KH; Chua, C; See, SJ; Tang, C; Wong, MC; Zaiden, N, 2008)
"Human GBM-derived cell lines U87, G44, G112, and the gliosarcoma-derived line G28 were treated with EPO, with and without combinations of irradiation or temozolomide (TMZ)."3.74Erythropoietin augments survival of glioma cells after radiation and temozolomide. ( Ehrenreich, H; Giese, A; Hasselblatt, M; Hassouna, I; Jelkmann, W; Kim, E; Rave-Fränk, M; Schulz-Schaeffer, W; Sperling, S, 2008)
"In the 4-year retrospective study, 31 patients with histologically confirmed malignant gliomas, in which 10 patients received radiotherapy followed by temozolomide (group A) and 21 patients received radiotherapy alone (group B)."3.74Radiotherapy followed by adjuvant temozolomide treatment of malignant glioma. ( Chang, HW; Chang, WN; Ho, JT; Lin, WC; Lin, YJ; Lu, CH; Wang, HC; Yang, TM, 2008)
"In this study, we investigated the precursor and active forms of a p53 small-molecule inhibitor for their effects on temozolomide (TMZ) antitumor activity against glioblastoma (GBM), using both in vitro and in vivo experimental approaches."3.74p53 Small-molecule inhibitor enhances temozolomide cytotoxic activity against intracranial glioblastoma xenografts. ( Berger, MS; Dinca, EB; Haas-Kogan, DA; James, CD; Lu, KV; Pieper, RO; Prados, MD; Sarkaria, JN; Vandenberg, SR, 2008)
"Glioblastoma patients undergoing treatment with surgery followed by radiation and temozolomide chemotherapy often develop a state of immunosuppression and are at risk for opportunistic infections and reactivation of hepatitis and herpes viruses."3.74Valproic acid related idiosyncratic drug induced hepatotoxicity in a glioblastoma patient treated with temozolomide. ( Hoorens, A; Neyns, B; Stupp, R, 2008)
" This epigenetic modification has been associated with a favorable prognosis in adult patients with glioblastoma (GBM) who receive temozolomide and other alkylating agents."3.74MGMT promoter methylation correlates with survival benefit and sensitivity to temozolomide in pediatric glioblastoma. ( Addo-Yobo, SO; Donson, AM; Foreman, NK; Gore, L; Handler, MH, 2007)
"Methylating drugs such as temozolomide (TMZ) are widely used in the treatment of brain tumours (malignant gliomas)."3.74Apoptosis in malignant glioma cells triggered by the temozolomide-induced DNA lesion O6-methylguanine. ( Batista, LF; Kaina, B; Menck, CF; Naumann, SC; Roos, WP; Weller, M; Wick, W, 2007)
"DNA alkylating agents including temozolomide (TMZ) and 1,3-bis[2-chloroethyl]-1-nitroso-urea (BCNU) are the most common form of chemotherapy in the treatment of gliomas."3.74The Fanconi anemia (FA) pathway confers glioma resistance to DNA alkylating agents. ( Chen, CC; D'Andrea, A; Taniguchi, T, 2007)
"Dose-limiting adverse effects of thrombocytopenia and leukopenia prevent augmentation of current temozolomide (TMZ) dosing protocols; therefore, we hypothesized that the direct intracranial delivery of TMZ would lead to improved efficacy in an animal model of malignant glioma in an animal model."3.74Local delivery of temozolomide by biodegradable polymers is superior to oral administration in a rodent glioma model. ( Brem, H; Brem, S; Caplan, J; Legnani, F; Li, K; Pradilla, G; Tyler, B, 2007)
"Following the resection of newly diagnosed or recurrent glioblastomas, local implantation of carmustine-impregnated biodegradable wafers (Gliadel) in the resection cavity constitutes an adjuvant therapy that can improve the possibilities of survival."3.74Fatal outcome related to carmustine implants in glioblastoma multiforme. ( Barcia, JA; Barcia-Mariño, C; Gallego, JM, 2007)
"The aim of this study was to investigate the effect of temozolomide (TZM) in combination with X-rays on proliferation and migration in human glioma spheroids."3.74The inhibition of proliferation and migration of glioma spheroids exposed to temozolomide is less than additive if combined with irradiation. ( Fehlauer, F; Muench, M; Rades, D; Richter, E, 2007)
"Glioblastomas are treated by surgical resection followed by radiotherapy [X-ray therapy (XRT)] and the alkylating chemotherapeutic agent temozolomide."3.74Loss of the mismatch repair protein MSH6 in human glioblastomas is associated with tumor progression during temozolomide treatment. ( Batchelor, TT; Betensky, RA; Cahill, DP; Codd, PJ; Curry, WT; Futreal, PA; Iafrate, AJ; Levine, KK; Louis, DN; Reavie, LB; Romany, CA; Stratton, MR, 2007)
"To evaluate the natural progression and the impact of temozolomide in low-grade gliomas and to correlate these changes with the profile of genetic alterations."3.74Dynamic history of low-grade gliomas before and after temozolomide treatment. ( Amiel-Benouaich, A; Capelle, L; Carpentier, AF; Cornu, P; Delattre, JY; Duffau, H; Guillevin, R; Hoang-Xuan, K; Kaloshi, G; Kujas, M; Laigle-Donadey, F; Lejeune, J; Mandonnet, E; Marie, Y; Mokhtari, K; Omuro, A; Ricard, D; Sanson, M; Taillibert, S, 2007)
"We report the case of a 30-year-old woman with glioblastoma multiforme (GBM) treated with surgery followed by concomitant Temozolomide (TMZ) and external beam radiation, which she tolerated well without any interruptions."3.74Unexpected case of aplastic anemia in a patient with glioblastoma multiforme treated with Temozolomide. ( Gujral, S; Jalali, R; Menon, H; Singh, P, 2007)
"To evaluate the predictive impact of chromosome 1p/19q deletions on the response and outcome of progressive low-grade gliomas (LGG) treated with up-front temozolomide (TMZ) chemotherapy."3.74Temozolomide for low-grade gliomas: predictive impact of 1p/19q loss on response and outcome. ( Benouaich-Amiel, A; Capelle, L; Carpentier, A; Cornu, P; Delattre, JY; Diakite, F; Duffau, H; Hoang-Xuan, K; Idbaih, A; Iraqi, W; Kaloshi, G; Laigle-Donadey, F; Lejeune, J; Mokhtari, K; Omuro, A; Paris, S; Polivka, M; Renard, MA; Sanson, M; Simon, JM; Taillibert, S, 2007)
"The use of adjuvant temozolomide (TMZ) in patients managed with surgery and adjuvant radiation therapy (RT) for glioblastoma multiforme (GBM) has been demonstrated to improve median and 2-year survival in a recent large international multicentre study."3.74Improved median survival for glioblastoma multiforme following introduction of adjuvant temozolomide chemotherapy. ( Ang, EL; Back, MF; Chan, SP; Lim, CC; Ng, WH; See, SJ; Yeo, TT, 2007)
" In this study, as we determined p53 gene mutation occurring in multinucleated giant cell glioblastoma, we investigated the role of Aurora-B in formation of multinucleated cells in human neoplasm cells with various p53 statuses as well as cytotoxity of glioma cells to temozolomide (TMZ), a common oral alkylating agent used in the treatment of gliomas."3.74Inhibition of Aurora-B function increases formation of multinucleated cells in p53 gene deficient cells and enhances anti-tumor effect of temozolomide in human glioma cells. ( Fujita, M; Inagaki, M; Katsumata, S; Mizuno, M; Nakahara, N; Natsume, A; Osawa, H; Satoh, Y; Tsuno, T; Wakabayashi, T; Yoshida, J, 2007)
" The potential therapeutic value of MGMT hypermethylation evaluation using MS-MLPA was shown in a group of 20 glioblastoma patients receiving temozolomide chemotherapy."3.74MS-MLPA: an attractive alternative laboratory assay for robust, reliable, and semiquantitative detection of MGMT promoter hypermethylation in gliomas. ( Boots-Sprenger, SH; Cornelissen, SJ; Dekkers, MM; Errami, A; Jeuken, JW; Sijben, A; Vriezen, M; Wesseling, P, 2007)
"Treatment of malignant glioma involves concomitant temozolomide and ionizing radiation (IR)."3.74Adenovirally delivered tumor necrosis factor-alpha improves the antiglioma efficacy of concomitant radiation and temozolomide therapy. ( Bickenbach, K; Galanopoulos, N; Pytel, P; Rawlani, V; Veerapong, J; Weichselbaum, RR; Yamini, B; Yu, X, 2007)
"To investigate the radiosensitizing potential of temozolomide (TMZ) for human glioblastoma multiforme (GBM) cell lines using single-dose and fractionated gamma-irradiation."3.74Differential radiosensitizing potential of temozolomide in MGMT promoter methylated glioblastoma multiforme cell lines. ( Hulsebos, TJ; Lafleur, MV; Leenstra, S; Slotman, BJ; Sminia, P; Stalpers, LJ; van den Berg, J; van Nifterik, KA, 2007)
"To evaluate efficacy and toxicity in elderly patients with glioblastoma multiforme (GBM) treated with postoperative radiochemotherapy with temozolomide (TMZ)."3.74Postoperative treatment of primary glioblastoma multiforme with radiation and concomitant temozolomide in elderly patients. ( Bischof, M; Combs, SE; Debus, J; Schulz-Ertner, D; Wagner, F; Wagner, J; Welzel, T, 2008)
"Methylation of the promoter region of the O ( 6 ) -methylguanine-DNA methyltransferase (MGMT) gene is known to be predictive of response to temozolomide treatment in patients with glioblastoma."3.74Variation of O(6)-methylguanine-DNA methyltransferase (MGMT) promoter methylation in serial samples in glioblastoma. ( Biggs, MT; Clarkson, A; Cook, RJ; Little, NS; McDonald, KL; McKenzie, CA; Messina, M; Parkinson, JF; Robinson, BG; Wheeler, HR, 2008)
"Diffusion tensor imaging and multiple voxel magnetic resonance spectroscopy were performed in the MRI follow-up of a patient with a glioma treated with temozolomide chemotherapy."3.74Diffusion tensor imaging and chemical shift imaging assessment of heterogeneity in low grade glioma under temozolomide chemotherapy. ( Enting, RH; Heesters, MA; Irwan, R; Meiners, LC; Oudkerk, M; Potze, JH; Sijens, PE; van der Graaf, WT, 2007)
"The purpose of this study was to report our experience with concomitant and adjuvant temozolomide (TMZ) with radiotherapy in patients with newly diagnosed glioblastoma multiforme (GBM)."3.74Encouraging experience of concomitant Temozolomide with radiotherapy followed by adjuvant Temozolomide in newly diagnosed glioblastoma multiforme: single institution experience. ( Basu, A; Goel, A; Gupta, T; Jalali, R; Menon, H; Munshi, A; Sarin, R, 2007)
" Temozolomide is an effective chemotherapeutic agent for patients with glioblastoma multiforme, but it induces significant lymphopenia."3.74Immunological responses in a patient with glioblastoma multiforme treated with sequential courses of temozolomide and immunotherapy: case study. ( Aldape, K; Archer, GE; Bigner, DD; Crutcher, L; Dey, M; Gilbert, M; Hassenbusch, SJ; Heimberger, AB; Hussain, SF; Mitchell, DA; Sampson, JH; Sawaya, R; Schmittling, B; Sun, W, 2008)
"Temozolomide (TMZ), given concurrently with radiotherapy (RT) and as adjuvant monotherapy afterwards, has led to improved survival in glioblastoma multiforme (GBM)."3.74The added value of concurrently administered temozolomide versus adjuvant temozolomide alone in newly diagnosed glioblastoma. ( Avutu, B; Barker, FG; Batchelor, TT; Chakravarti, A; Henson, JW; Hochberg, FH; Loeffler, JS; Martuza, RL; Sher, DJ, 2008)
"32 patients 70 years of age or older with a newly diagnosed glioblastoma and a Karnofsky performance status (KPS) > or = 70 were treated with RT (daily fractions of 2 Gy for a total of 60 Gy) plus temozolomide at the dose of 75 mg/m(2) per day followed by six cycles of adjuvant temozolomide (150-200 mg/m(2) for 5 days during each 28-day cycle)."3.74Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma in elderly patients. ( Bozzao, A; De Paula, U; De Sanctis, V; Filippone, F; Lanzetta, G; Maurizi Enrici, R; Minniti, G; Muni, R; Osti, MF; Tombolini, V; Valeriani, M, 2008)
"The oral alkylating agent, temozolomide (Temodal: TMZ), is the only anticancer drug that has been shown in a phase III study to improve survival in glioblastoma (GBM) when administered with concomitant radiotherapy."3.74[Temozolomide: Temodal]. ( Nakamura, O; Saito, K; Shinoura, N; Tabei, Y; Takahashi, M; Yamada, R, 2008)
"Standard therapy for glioblastoma (GBM) is temozolomide (TMZ) administration, initially concurrent with radiotherapy (RT), and subsequently as maintenance therapy."3.74MGMT promoter methylation status can predict the incidence and outcome of pseudoprogression after concomitant radiochemotherapy in newly diagnosed glioblastoma patients. ( Andreoli, A; Bartolini, S; Bertorelle, R; Blatt, V; Brandes, AA; Calbucci, F; Ermani, M; Franceschi, E; Frezza, G; Leonardi, M; Pession, A; Spagnolli, F; Tallini, G; Tosoni, A, 2008)
"The in vitro cytotoxicity of TRA-8 and temozolomide (Tmz) or RT was examined using adenosine triphosphate-dependent viability and clonogenic survival assays with five glioma cell lines."3.74Enhancement of glioma radiotherapy and chemotherapy response with targeted antibody therapy against death receptor 5. ( Belenky, ML; Buchsbaum, DJ; Fiveash, JB; Gillespie, GY; Oliver, PG; Zhou, T, 2008)
"To evaluate the feasibility, safety and efficacy of daily temozolomide concurrent with postoperative radiotherapy in malignant glioma."3.73Efficacy and toxicity of postoperative temozolomide radiochemotherapy in malignant glioma. ( Eich, HT; Kocher, M; Kunze, S; Müller, RP; Semrau, R, 2005)
"Patients with glioblastoma containing a methylated MGMT promoter benefited from temozolomide, whereas those who did not have a methylated MGMT promoter did not have such a benefit."3.73MGMT gene silencing and benefit from temozolomide in glioblastoma. ( Bromberg, JE; Cairncross, JG; de Tribolet, N; Diserens, AC; Gorlia, T; Hainfellner, JA; Hamou, MF; Hau, P; Hegi, ME; Janzer, RC; Kros, JM; Mariani, L; Mason, W; Mirimanoff, RO; Stupp, R; Weller, M, 2005)
" This was of interest because E6 silencing of p53 sensitizes U87MG astrocytic glioma cells to BCNU and temozolomide (TMZ), cytotoxic drugs that are modestly helpful in the treatment of aggressive astrocytic gliomas."3.73Pharmaceutical-mediated inactivation of p53 sensitizes U87MG glioma cells to BCNU and temozolomide. ( Cairncross, JG; Mymryk, JS; Xu, GW, 2005)
"The aim of this study was to evaluate the efficacy and safety of carmustine (BCNU) in combination with temozolomide as first-line chemotherapy before and after radiotherapy (RT) in patients with inoperable, newly diagnosed glioblastoma multiforme (GBM)."3.73Temozolomide in combination with BCNU before and after radiotherapy in patients with inoperable newly diagnosed glioblastoma multiforme. ( Barrié, M; Braguer, D; Chinot, O; Couprie, C; Dufour, H; Figarella-Branger, D; Grisoli, F; Hoang-Xuan, K; Martin, PM; Muracciole, X; Peragut, JC, 2005)
"Cimetidine added to temozolomide compared with temozolomide alone induced survival benefits in nude mice with U373 human glioblastoma multiforme (GBM) cells orthotopically xenografted in the brain."3.73Combined cimetidine and temozolomide, compared with temozolomide alone: significant increases in survival in nude mice bearing U373 human glioblastoma multiforme orthotopic xenografts. ( Brotchi, J; Camby, I; Darro, F; Gabius, J; Gaussin, JF; James, S; Kiss, R; Lefranc, F, 2005)
"There are new scientific data concerning the treatment of patients with glioblastoma multiforme with concomitant and adjuvant temozolomide following surgery and radiotherapy."3.73[Temozolomide in patients with a glioblastoma multiforme: new developments]. ( Bromberg, JE; Postma, TJ, 2005)
"To describe the results of the treatment of recurrent glioma with temozolomide."3.73[Favourable result for temozolomide in recurrent high-grade glioma]. ( Enting, RH; Kros, JM; Sillevis Smitt, PA; Taal, W; van den Bent, MJ; van der Rijt, CD; van Heuvel, I, 2005)
"Temozolomide (TMZ) is an oral alkylating agent with demonstrated efficacy as therapy for glioblastoma multiforme (GBM) and anaplastic astrocytoma."3.73Economic evaluation of temozolomide in the treatment of recurrent glioblastoma multiforme. ( Hallinen, T; Kivioja, A; Martikainen, JA; Vihinen, P, 2005)
" Treatment of glioblastoma multiforme by temozolomide is considered as a paradigm."3.73Simulating chemotherapeutic schemes in the individualized treatment context: the paradigm of glioblastoma multiforme treated by temozolomide in vivo. ( Antipas, VP; Stamatakos, GS; Uzunoglu, NK, 2006)
"The chemotherapeutic agent temozolomide (TMZ) and the anti-angiogenic agent thalidomide (THD) have both demonstrated anti-tumor activity in patients with recurrent malignant glioma."3.73Combination treatment with temozolomide and thalidomide inhibits tumor growth and angiogenesis in an orthotopic glioma model. ( Jeon, HJ; Kim, H; Kim, JH; Kim, JS; Kim, JT; Kim, MH; Kim, YJ; Lee, DS; Nam, DH; Park, SY; Shin, T; Son, MJ; Song, HS, 2006)
"The purpose of this study was to determine whether a combination treatment of temozolomide with celecoxib is effective in the rat orthotopic glioma model."3.73Combination celecoxib and temozolomide in C6 rat glioma orthotopic model. ( Groves, MD; Kang, SG; Kim, JS; Nam, DH; Park, K, 2006)
"The aim of this study was to determine the efficacy and tolerability of a biochemotherapy regimen, including low-dose subcutaneous interleukin-2 and temozolomide, in patients with metastatic melanoma."3.73Biochemotherapy with temozolomide, cisplatin, vinblastine, subcutaneous interleukin-2 and interferon-alpha in patients with metastatic melanoma. ( Carrera, C; Castel, T; Conill, C; Gascón, P; González Cao, M; Herrero, J; Malvehy, J; Martí, R; Martín, M; Mellado, B; Puig, S; Sánchez, M, 2006)
"This is a report of a 53 year-old man with a glioblastoma multiforme (GBM) treated with an excessive dose of temozolomide (TMZ)."3.73Complications of a temozolomide overdose: a case report. ( Kiem, HP; Partap, S; Peterson, RA; Schuetze, S; Silber, JR; Spence, AM, 2006)
"Severe temozolomide-induced immunosuppression, exacerbated by corticosteroids, with profound T-cell lymphocytopenia and simultaneous opportunistic infections with Pneumocystis jiroveci pneumonia, brain abscess with Listeria monocytogenes, and cutaneous Kaposi's sarcoma."3.73Listeria brain abscess, Pneumocystis pneumonia and Kaposi's sarcoma after temozolomide. ( Bally, F; Christen, G; de Ribaupierre, S; Ganière, V; Guillou, L; Pica, A; Stupp, R, 2006)
"Previously we defined a pathway of transforming growth factor beta (TGF-beta) and stromal cell-derived factor-1/CXC chemokine ligand 12 (SDF-1alpha/CXCL12) dependent migration of adult haematopoietic stem and progenitor cells (HPC) towards glioma cells in vitro and their homing to experimental gliomas in vivo."3.73Irradiation and hypoxia promote homing of haematopoietic progenitor cells towards gliomas by TGF-beta-dependent HIF-1alpha-mediated induction of CXCL12. ( Frank, B; Möhle, R; Tabatabai, G; Weller, M; Wick, W, 2006)
"To re-evaluate the cost effectiveness and median overall survival (OS) achieved in patients with recurrent malignant gliomas treated with temozolomide in British Columbia, as compared to previous lomustine use in the same patient population based on updated outcomes data."3.73Re-evaluation of the cost effectiveness of temozolomide for malignant gliomas in British Columbia. ( Mabasa, VH; Taylor, SC, 2006)
"Temozolomide (TMZ) is a DNA methylating agent that has shown promising antitumor activity against high grade glioma."3.73Potentiation of antiglioma effect with combined temozolomide and interferon-beta. ( Hong, YK; Joe, YA; Kim, TG; Park, JA, 2006)
"In this IRB-approved retrospective study, we analyzed the efficacy of temozolomide on World Health Organization Grade II and III oligodendrogliomas, as well as mixed oligoastrocytomas, to determine if a correlation exists between the tumors' 1p status and control of growth by this new oral agent."3.72Impact of chromosome 1p status in response of oligodendroglioma to temozolomide: preliminary results. ( Barnett, G; Chahlavi, A; Elson, P; Kanner, A; Peereboom, D; Staugaitis, SM, 2003)
"Temozolomide (TMZ) is a DNA methylating agent that has shown promising antitumor activity in recent clinical trials against high grade gliomas, metastatic melanoma, and brain lymphoma."3.72Systemic administration of GPI 15427, a novel poly(ADP-ribose) polymerase-1 inhibitor, increases the antitumor activity of temozolomide against intracranial melanoma, glioma, lymphoma. ( D'Amati, G; Graziani, G; Kalish, V; Leonetti, C; Portarena, I; Scarsella, M; Tentori, L; Vergati, M; Xu, W; Zhang, J; Zupi, G, 2003)
"The present observation suggests that temozolomide may be an active and well tolerated treatment for malignant melanoma brain metastases."3.72Complete response of multiple melanoma brain metastases after treatment with temozolomide. ( Dvorak, J; Hadzi-Nikolov, D; Melichar, B; Petera, J; Zizka, J, 2004)
"The Chk1 and p38 mitogen-activated protein kinase (MAPK) pathways play key roles in the G2 arrest caused by exposing glioma cells to temozolomide (TMZ)."3.72Cooperative function of Chk1 and p38 pathways in activating G2 arrest following exposure to temozolomide. ( Berger, MS; Hirose, Y; Katayama, M; Pieper, RO, 2004)
"The phase III randomised European Organisation for Research and Treatment of Cancer (EORTC) and National Cancer Institute of Canada Clinical Trail Group (NCIC) Intergroup trial (EORTC 26981/22981; CE3) compares irradiation alone with irradiation plus temozolomide for patients with glioblastoma multiforme (GBM)."3.72Quality assurance of the EORTC 26981/22981; NCIC CE3 intergroup trial on radiotherapy with or without temozolomide for newly-diagnosed glioblastoma multiforme: the individual case review. ( Ataman, F; Fisher, B; Mirimanoff, RO; Poortmans, P; Stupp, R, 2004)
"Using a methylation-specific PCR approach, we assessed the methylation status of the CpG island of MGMT in 92 glioma patients who received temozolomide as first-line chemotherapy or as treatment for relapses."3.72CpG island hypermethylation of the DNA repair enzyme methyltransferase predicts response to temozolomide in primary gliomas. ( Aguirre-Cruz, L; Arribas, L; Balaña, C; Esteller, M; García-Lopez, JL; García-Villanueva, M; Paz, MF; Piquer, J; Pollan, M; Reynes, G; Rojas-Marcos, I; Safont, MJ; Sanchez-Cespedes, M; Yaya-Tur, R, 2004)
"Temozolomide is an oral alkylating agent shown to have modest efficacy in the treatment of glioblastoma multiforme."3.72Transcriptional targeting of adenovirally delivered tumor necrosis factor alpha by temozolomide in experimental glioblastoma. ( Gillespie, GY; Kufe, DW; Weichselbaum, RR; Yamini, B; Yu, X, 2004)
"Temozolomide, an imidazotetrazine prodrug has shown activity in phase II studies in patients with high-grade glioma at first recurrence."3.71Temozolomide as second-line chemotherapy for relapsed gliomas. ( Ashley, S; Brada, M; Dowe, A; Hines, F; Kong, A; Short, SC; Traish, D; Trent, S, 2002)
"Temozolomide (TZM) is a novel methylating agent currently under investigation for treatment of recurrent high-grade gliomas."3.71Poly(ADP-ribose) polymerase inhibitor increases growth inhibition and reduces G(2)/M cell accumulation induced by temozolomide in malignant glioma cells. ( Graziani, G; Navarra, P; Portarena, I; Scerrati, M; Tentori, L; Torino, F, 2002)
" 11 (44%) patients showed cerebral metastases prior to therapy with temozolomide."3.71[Temozolomide as therapeutic option for patients with metastatic melanoma and poor prognosis]. ( Christophers, E; Frick, S; Haacke, TC; Hauschild, A; Lischner, S; Rosien, F; Schäfer, F, 2002)
"A case is reported in which temozolomide, a promising new DNA alkylating agent, was successfully used to treat radiation refractory metastatic brain tumors arising from primary breast cancer."3.71Hemorrhagic cystitis as an unexpected adverse reaction to temozolomide: case report. ( Isaacson, BJ; Islam, R; Ratanawong, C; Tipping, SJ; Zickerman, PM, 2002)
"Temozolomide has an evolving role in the treatment of high grade gliomas."3.71An Australian experience with temozolomide for the treatment of recurrent high grade gliomas. ( Ashley, DL; Cher, L; Harris, MT; Rosenthal, MA, 2001)
"The authors determined the tolerance, response rate, and duration of recurrent anaplastic oligodendroglioma in 30 patients to temozolomide given orally at 150 to 200 mg/m2 on days 1 through 5 in cycles of 28 days."3.71Temozolomide chemotherapy in recurrent oligodendroglioma. ( Brandes, AA; Carpentier, AF; Eskens, FA; Keime-Guibert, F; Kros, JM; Taphoorn, MJ; van den Bent, MJ, 2001)
"Gene therapy for malignant glioma with the herpes simplex virus thymidine kinase/ganciclovir (HSV-tk/GCV) system is already in the stage of clinical trials, but still needs major improvement to achieve greater clinical efficacy."3.71Temozolomide enhances herpes simplex virus thymidine kinase/ganciclovir therapy of malignant glioma. ( Chou, TC; Droege, JW; Fels, C; Kramm, CM; Rainov, NG; Schäfer, C, 2001)
"To investigate the effect of temozolomide, a 3-methyl derivative of mitozolomide in combination with X-rays in human glioma-derived cell lines."3.70Survival of human glioma cells treated with various combination of temozolomide and X-rays. ( Heimans, JJ; Slotman, BJ; van den Berg, J; van der Valk, P; van Rijn, J, 2000)
"The activity of temozolomide combined with irinotecan (CPT-11) was evaluated against eight independent xenografts (four neuroblastomas, three rhabdomyosarcomas, and one glioblastoma)."3.70Antitumor activity of temozolomide combined with irinotecan is partly independent of O6-methylguanine-DNA methyltransferase and mismatch repair phenotypes in xenograft models. ( Brent, TP; Cheshire, PJ; Friedman, HS; Houghton, PJ; Kirstein, MN; Poquette, CA; Richmond, LB; Stewart, CF; Tan, M, 2000)
" Temozolomide is a novel methylating agent with proven efficacy against malignant gliomas (MGs) after systemic administration but with dose-limiting myelotoxicity."3.70Temozolomide delivered by intracerebral microinfusion is safe and efficacious against malignant gliomas in rats. ( Archer, GE; Bigner, DD; Friedman, AH; Friedman, HS; Heimberger, AB; Hulette, C; McLendon, RE; Sampson, JH, 2000)
"The in vitro cytotoxicity of 8-carbamoyl-3-methylimidazo [5,1-d]-1,2,3,5-tetrazine-4(3H)-one (temozolomide) with concurrent X-irradiation was examined in a human glioblastoma cell line (U373MG) as a potential radio-chemotherapeutic treatment for malignant glioma."3.69In vitro evaluation of temozolomide combined with X-irradiation. ( Glaser, MG; Marcus, K; Newlands, ES; Porteous, JK; Wedge, SR, 1997)
"Glioblastoma is the most common and most aggressive type of primary brain tumor."3.30Granulocyte-macrophage colony stimulating factor enhances efficacy of nimustine rendezvousing with temozolomide plus irradiation in patients with glioblastoma. ( Bu, XY; Cheng, X; Kong, LF; Luo, JC; Qu, MQ; Wang, YW; Yan, ZY; Yang, DY; Zhao, YW, 2023)
"Glioblastoma is the most lethal primary brain cancer."3.30Association of Autologous Tumor Lysate-Loaded Dendritic Cell Vaccination With Extension of Survival Among Patients With Newly Diagnosed and Recurrent Glioblastoma: A Phase 3 Prospective Externally Controlled Cohort Trial. ( Abram, S; Aiken, RD; Ansstas, G; Ashkan, K; Avigan, DE; Baskin, DS; Battiste, JD; Bosch, ML; Bota, DA; Boynton, AL; Brem, S; Brenner, AJ; Campian, JL; Chaudhary, R; Cobbs, CS; D'Andre, S; Dunbar, EM; Elinzano, H; Etame, AB; Ewend, MG; Fink, KL; Geoffroy, FJ; Giglio, P; Gligich, O; Goldlust, SA; Grewal, J; Heth, JA; Iwamoto, FM; Kesari, S; Khagi, S; Kim, L; Krex, D; Lacroix, M; Lee, IY; Liau, LM; Lillehei, K; Lindhorst, SM; Loudon, WG; Lovick, DS; Lutzky, J; Martinez, NL; Mathieu, D; May, SA; Meisel, HJ; Mikkelsen, T; Moshel, YA; Mulholland, PJ; Nadji-Ohl, M; Nam, JY; New, PZ; Peak, S; Pearlman, ML; Petrecca, K; Piccioni, DE; Pillainayagam, CP; Pluard, TJ; Portnow, J; Prins, RM; Salacz, ME; Sanchin, L; Schulder, M; Sloan, A; Taylor, LP; Thompson, RC; Toms, SA; Tran, DD; Trusheim, JE; Tse, V; Villano, JL; Wagner, SA; Walbert, T; Walter, KA; Wu, JK, 2023)
"Standard treatment of glioblastoma consisting of maximal safe resection, adjuvant radiotherapy and chemotherapy with temozolomide, results in an overall median survival of 14."3.11Treatment of glioblastoma with re-purposed renin-angiotensin system modulators: Results of a phase I clinical trial. ( Burgess, C; FitzJohn, T; Kaye, AH; O'Rawe, M; Pandey, R; Sim, D; Tan, ST; Wickremesekera, AC; Young, D, 2022)
"The majority of metastatic colorectal cancers (mCRC) are mismatch repair (MMR) proficient and unresponsive to immunotherapy, whereas MMR-deficient (MMRd) tumors often respond to immune-checkpoint blockade."3.11Temozolomide Treatment Alters Mismatch Repair and Boosts Mutational Burden in Tumor and Blood of Colorectal Cancer Patients. ( Amatu, A; Barault, L; Bardelli, A; Bartolini, A; Battuello, P; Bonoldi, E; Cassingena, A; Crisafulli, G; Di Nicolantonio, F; Germano, G; Idotta, L; Lazzari, L; Luraghi, P; Macagno, M; Marsoni, S; Mauri, G; Morano, F; Personeni, N; Pessei, V; Pietrantonio, F; Sartore-Bianchi, A; Siena, S; Tosi, F; Valtorta, E; Vitiello, PP; Zampino, MG, 2022)
"Obesity was associated with shorter survival in patients with MGMT methylated glioblastoma (median OS 22."3.11Prognostic impact of obesity in newly-diagnosed glioblastoma: a secondary analysis of CeTeG/NOA-09 and GLARIUS. ( Borger, V; Goldbrunner, R; Güresir, E; Hau, P; Herrlinger, U; Krex, D; Pietsch, T; Potthoff, AL; Sabel, M; Schäfer, N; Schaub, C; Schlegel, U; Schneider, M; Seidel, C; Steinbach, JP; Tzaridis, T; Vatter, H; Weller, J; Zeyen, T, 2022)
"The most frequently diagnosed primary brain tumor is glioblastoma (GBM)."3.11A phase II open label, single arm study of hypofractionated stereotactic radiotherapy with chemoradiotherapy using intensity-modulated radiotherapy for newly diagnosed glioblastoma after surgery: the HSCK-010 trial protocol. ( Dai, J; Gong, X; Guan, Y; Han, L; Li, J; Liu, X; Liu, Y; Lu, Q; Mei, G; Pan, L; Pan, M; Wang, E; Wang, X; Wang, Y; Yang, J; Zhu, H, 2022)
" Common nonocular treatment-emergent adverse events (TEAEs) with both second-line and first-line Depatux-M included lymphopenia (42%, 33%, respectively), thrombocytopenia (39%, 47%), alanine aminotransferase increase (29%, 47%), and aspartate aminotransferase increase (24%, 60%); incidence of grade ≥3 TEAEs was 66% and 53%, respectively."3.01Safety and efficacy of depatuxizumab mafodotin in Japanese patients with malignant glioma: A nonrandomized, phase 1/2 trial. ( Asai, K; Beppu, T; Date, I; Kagawa, N; Kanamori, M; Kasai, S; Kobayashi, H; Kumabe, T; Kuroda, J; Matsuda, M; Mishima, K; Muragaki, Y; Nagane, M; Narita, Y; Nishimura, Y; Ocampo, C; Ueki, K; Xiong, H; Yamada, M, 2021)
" Only one possibly treatment-related treatment emergent adverse event (TEAE), Grade 1 gingival swelling, was observed."3.01Safety and tolerability of asunercept plus standard radiotherapy/temozolomide in Asian patients with newly-diagnosed glioblastoma: a phase I study. ( Chen, KT; Hsu, PW; Huang, HL; Jung, SM; Ke, YX; Lin, YJ; Toh, CH; Tsai, HC; Tseng, CK; Wei, KC, 2021)
" Glioblastoma is the most aggressive and diffusely infiltrative primary brain tumor."3.01Updates in the Management of Recurrent Glioblastoma Multiforme. ( Ansari, A; Prajapati, HP, 2023)
"Gliomas are the most common primary central nervous system tumors; despite recent advances in diagnosis and treatment, glioma patients generally have a poor prognosis."3.01Current and promising treatment strategies in glioma. ( Bebyn, M; Furtak, J; Koper, A; Koper, K; Śledzińska, P, 2023)
"Glioma is a deadly form of brain cancer, and the difficulty of treating glioma is exacerbated by the chemotherapeutic resistance developed in the tumor cells over the time of treatment."3.01Iron Oxide Nanoparticles Decorated with Functional Peptides for a Targeted siRNA Delivery to Glioma Cells. ( Chung, S; Huang, J; Sugimoto, Y; Zhang, M, 2023)
"Malignant primary brain tumors cause more than 15 000 deaths per year in the United States."3.01Glioblastoma and Other Primary Brain Malignancies in Adults: A Review. ( Mellinghoff, IK; Schaff, LR, 2023)
"As the most malignant primary brain tumor in adults, a diagnosis of glioblastoma multiforme (GBM) continues to carry a poor prognosis."3.01Advanced Bioinformatics Analysis and Genetic Technologies for Targeting Autophagy in Glioblastoma Multiforme. ( Manea, AJ; Ray, SK, 2023)
"Temozolomide (TMZ) is a DNA alkylating agent that can cross the blood-brain barrier."3.01Expert opinion on translational research for advanced glioblastoma treatment. ( Cui, X; Kang, C; Wang, Q; Wang, Y; Zhou, J, 2023)
"Glioblastoma Multiforme (GBM) is the primary brain tumor and accounts for 200,000 deaths each year worldwide."3.01Novel sights on therapeutic, prognostic, and diagnostics aspects of non-coding RNAs in glioblastoma multiforme. ( Adusumilli, K; Angirekula, HSR; Chamarthy, S; Mekala, JR, 2023)
"Glioblastoma is the most common and lethal brain tumor in adults."3.01Current advances in temozolomide encapsulation for the enhancement of glioblastoma treatment. ( Iturrioz-Rodríguez, N; Matheu, A; Sampron, N, 2023)
"TMZ is utilized in brain cancer removal, but resistance is a drawback."3.01Epigenetic regulation of temozolomide resistance in human cancers with an emphasis on brain tumors: Function of non-coding RNAs. ( Ajdari, A; Aref, AR; Etemad, S; Eydivandi, S; Fan, X; Hushmandi, K; Karimi, AS; Khorrami, R; Nabavi, N; Rahmanian, P; Rajabi, R; Rashidi, M; Rezaee, A; Sanadgol, N; Tehrany, PM; Tirabadi, FJ; Zandieh, MA; Zou, R, 2023)
"Atorvastatin was not shown to improve PFS-6."3.01Atorvastatin in combination with radiotherapy and temozolomide for glioblastoma: a prospective phase II study. ( Aldanan, S; Alghareeb, WA; Alhussain, H; AlNajjar, FH; Alsaeed, E; Alsharm, AA; Altwairgi, AK; Balbaid, AAO; Orz, Y, 2021)
" Methods This is an open-label, 2-arm Phase 1b/2a study (N = 56) of galunisertib (intermittent dosing: 14 days on/14 days off per cycle of 28 days) in combination with TMZ/RTX (n = 40), versus a control arm (TMZ/RTX, n = 16)."2.94Phase 1b/2a study of galunisertib, a small molecule inhibitor of transforming growth factor-beta receptor I, in combination with standard temozolomide-based radiochemotherapy in patients with newly diagnosed malignant glioma. ( Burkholder, T; Capper, D; Cleverly, AL; Desjardins, A; Estrem, ST; Forsyth, P; Guba, SC; Gueorguieva, I; Lahn, MM; Rodon, J; Suarez, C; Wang, S; Wick, A, 2020)
"Primary end point is freedom from new brain metastases at 1 year."2.94Temozolomide in secondary prevention of HER2-positive breast cancer brain metastases. ( Armstrong, TS; Biassou, N; Brastianos, PK; Burton, E; Carter, S; Gilbert, MR; Gril, B; Houston, N; Lipkowitz, S; Lyden, D; Smart, DD; Steeg, PS; Steinberg, SM; Zimmer, AS, 2020)
" In clinical practice, Chinese doctors often use radiotherapy combined with temozolomide (TMZ) to treat these patients, although large-scale prospective studies are lacking."2.90Radiotherapy versus radiotherapy combined with temozolomide in high-risk low-grade gliomas after surgery: study protocol for a randomized controlled clinical trial. ( Guan, H; He, L; He, Y; Mu, X; Peng, X; Wang, J; Wang, Y, 2019)
" Common adverse events (AEs) were blurred vision (63%), fatigue (38%), and photophobia (35%)."2.90Safety and efficacy of depatuxizumab mafodotin + temozolomide in patients with EGFR-amplified, recurrent glioblastoma: results from an international phase I multicenter trial. ( Ansell, PJ; Bain, E; Butowski, N; Gan, HK; Gomez, E; Holen, KD; Kumthekar, P; Lassman, AB; Lee, HJ; Lwin, Z; Maag, D; Merrell, R; Mikkelsen, T; Nabors, LB; Papadopoulos, KP; Penas-Prado, M; Reardon, DA; Roberts-Rapp, L; Scott, AM; Simes, J; van den Bent, MJ; Walbert, T; Wheeler, H; Xiong, H, 2019)
"Cerebral edema was assessed at 4, 12, 22 and 34 weeks post-surgery, together with steroids consumption and patients' psychological status."2.90A novel lecithin-based delivery form of Boswellic acids as complementary treatment of radiochemotherapy-induced cerebral edema in patients with glioblastoma multiforme: a longitudinal pilot experience. ( Bertuccioli, A; Botta, L; Bruzzone, MG; Cuccarini, V; Di Pierro, F; Fariselli, L; Lamperti, E; Petruzzi, A; Simonetti, G, 2019)
" The aim of this study was to evaluate the efficacy of moderately hypofractionated simultaneous integrated boost intensity-modulated radiotherapy (SIB-IMRT) combined with temozolomide (TMZ) for the postoperative treatment of GBM."2.90Efficacy of moderately hypofractionated simultaneous integrated boost intensity-modulated radiotherapy combined with temozolomide for the postoperative treatment of glioblastoma multiforme: a single-institution experience. ( Chen, G; Chen, L; Li, G; Li, Q; Luo, W; Lv, S; Zhong, L; Zhou, P, 2019)
"Lapatinib was administered at 2500 mg twice daily for two consecutive days per week on a weekly basis throughout concomitant and adjuvant standard therapy."2.84Report of safety of pulse dosing of lapatinib with temozolomide and radiation therapy for newly-diagnosed glioblastoma in a pilot phase II study. ( Cloughesy, TF; Faiq, N; Green, R; Green, S; Hu, J; Lai, A; Mellinghoff, I; Nghiemphu, PL; Yu, A, 2017)
" The observation index of both groups included the short- and long-term clinical efficacies, improvement of symptoms and signs, quality of life (QOL), and adverse responses."2.84Efficacy and safety of temozolomide plus whole-brain radiotherapy in the treatment of intracranial metastases. ( Liu, HP; Wang, JW; Zheng, KB, 2017)
"Cancer is one of the main causes of human mortality and brain tumors, including invasive pituitary adenomas, medulloblastomas and glioblastomas are common brain malignancies with poor prognosis."2.82Oxamate targeting aggressive cancers with special emphasis to brain tumors. ( Altinoz, MA; Ozpinar, A, 2022)
"Apatinib is a novel, oral, small-molecule tyrosine kinase inhibitor that mainly targets vascular endothelial growth factor receptor-2 (VEGFR-2) to inhibit angiogenesis."2.82Combining apatinib and temozolomide for brainstem glioblastoma: a case report and review of literature. ( Sun, X; Xu, X; Xu, Y; Zhan, W; Zhao, L; Zhu, Y, 2022)
" There is insufficient data to make a recommendation about which alternative TMZ dosing provides the best benefits."2.82Congress of Neurological Surgeons systematic review and evidence-based guidelines update on the role of cytotoxic chemotherapy and other cytotoxic therapies in the management of progressive glioblastoma in adults. ( Germano, IM; Olson, JJ; Ormond, DR; Wen, P; Ziu, M, 2022)
" Although these beneficial effects are promising, the efficacy of natural compounds in glioblastoma is limited due to their bioavailability and blood-brain barrier permeability."2.82Natural Compounds as Promising Adjuvant Agents in The Treatment of Gliomas. ( Gigli, G; Leporatti, S; Persano, F, 2022)
" TMZ is an orally bioavailable prodrug, which is well absorbed from the gastrointestinal tract and is converted to its active alkylating metabolite 5-(3-methyl triazen-1-yl)imidazole-4-carbozamide (MTIC) spontaneously in physiological condition that does not require hepatic involvement."2.82Temozolomide Efficacy and Metabolism: The Implicit Relevance of Nanoscale Delivery Systems. ( Alyautdin, R; Chubarev, V; Grigorevskikh, E; Ismail, N; Merkulov, V; Petrenko, D; Smolyarchuk, E; Sologova, S; Syzrantsev, N, 2022)
" In addition, OS, PFS and adverse event (AE) data on ndGBM and recurrent GBM (rGBM) were assessed."2.82Comparative efficacy and safety of therapeutics for elderly glioblastoma patients: A Bayesian network analysis. ( Li, H; Ma, W; Qu, T; Wang, Y; Wu, J; Xia, Y; Xing, H; Zhao, B, 2022)
"Glioblastoma is the most aggressive form of brain tumor, accounting for the highest mortality and morbidity rates."2.82Nanomedicine for glioblastoma: Progress and future prospects. ( Baig, MH; Cho, JY; Dong, JJ; Hatiboglu, MA; Imran, MA; Khan, I; Khan, MI; Mahfooz, S, 2022)
"Glioblastoma is a fatal brain tumor with a bleak prognosis."2.82Glioblastoma and Methionine Addiction. ( Sowers, LC; Sowers, ML, 2022)
"(1) Background: Glioblastoma is the most frequent and lethal primary tumor of the central nervous system."2.82Glioblastoma Treatment: State-of-the-Art and Future Perspectives. ( Celis-López, MÁ; Cid-Sánchez, DR; Contreras-Palafox, GA; Flores-Vázquez, JG; Gutiérrez-Aceves, GA; Heredia-Gutiérrez, JC; Hernández-Sánchez, LC; Macías-González, MDS; Moreno-Jiménez, S; Moscardini-Martelli, J; Olmos-Guzmán, A; Ortiz-Arce, CS; Pérez, SR; Rodríguez-Camacho, A; Suárez-Campos, JJE; Torres-Ríos, JA, 2022)
"Gliomas are the deadliest of all primary brain tumors, and they constitute a serious global health problem."2.82MicroRNA delivery systems in glioma therapy and perspectives: A systematic review. ( Abrahantes-Pérez, MDC; Barajas-Olmos, F; García-Ortiz, H; Hernández-Cuenca, YE; Jiménez-Morales, JM; Orozco, L; Quiñones-Hinojosa, A; Reyes-Abrahantes, A; Reyes-González, J; Ruiz-García, H, 2022)
"Glioblastoma, the most common malignant primary brain tumor, remains a lethal disease with few therapeutic options."2.82Immune-checkpoint inhibitors for glioblastoma: what have we learned? ( Omuro, A, 2022)
"Gliomas are tumors of the primary central nervous system associated with poor prognosis and high mortality."2.82MicroRNAs, Key Regulators in Glioma Progression as Potential Therapeutic Targets for Chinese Medicine. ( Du, J; Fan, H; Kuang, X; Peng, F; Xie, X, 2022)
"Therefore, brain cancer research models need to aim to recapitulate glioblastoma stem cell function, whilst remaining amenable for analysis."2.82Utility of the Cerebral Organoid Glioma 'GLICO' Model for Screening Applications. ( Gray, C; Paterson, E; Peng, L; Tan, ST; Weth, FR, 2022)
"Glioblastoma is the most frequently diagnosed type of primary brain tumour in adults."2.82DDRugging glioblastoma: understanding and targeting the DNA damage response to improve future therapies. ( Collis, SJ; Rominiyi, O, 2022)
"Temozolomide was administered twice daily on days -10 to -6, followed by thiotepa 300 mg/m(2) per day and carboplatin dosed using the Calvert formula or body surface area on days -5 to -3, with AHCR day 0."2.82Phase I study of temozolomide in combination with thiotepa and carboplatin with autologous hematopoietic cell rescue in patients with malignant brain tumors with minimal residual disease. ( Belasco, JB; Cervone, KA; Egan, G; Finlay, JL; Gardner, SL; Philips, PC, 2016)
"Glioblastoma is the most common malignant brain tumor in adults."2.82Prognostic value of health-related quality of life for death risk stratification in patients with unresectable glioblastoma. ( Anota, A; Bonnetain, F; Campello, C; Castera, D; Chauffert, B; Chinot, O; Dabakuyo, S; Dalban, C; Ducray, F; Durando, X; Fabbro, M; Feuvret, L; Frappaz, D; Frenay, M; Ghiringhelli, F; Guillamo, JS; Paquette, B; Schott, R; Skrzypski, J; Taillandier, L; Taillia, H; Tennevet, I; Vernerey, D, 2016)
"Treatment was bortezomib 1."2.82A phase II trial evaluating the effects and intra-tumoral penetration of bortezomib in patients with recurrent malignant gliomas. ( Bredel, M; Chandler, JP; Ferrarese, R; Grimm, SA; Helenowski, I; Levy, RM; Muro, K; Paton, M; Rademaker, A; Raizer, JJ; Rosenow, J, 2016)
"Retreatment with temozolomide (TMZ) is one treatment option."2.80Dendritic cell vaccination combined with temozolomide retreatment: results of a phase I trial in patients with recurrent glioblastoma multiforme. ( Ancelet, LR; Bauer, E; Dzhelali, M; Findlay, MP; Gasser, O; Hamilton, DA; Hermans, IF; Hunn, MK; Mester, B; Sharples, KJ; Wood, CE, 2015)
"Everolimus (70 mg/wk) was started 1 week prior to radiation and TMZ, followed by adjuvant TMZ, and continued until disease progression."2.80A phase II trial of everolimus, temozolomide, and radiotherapy in patients with newly diagnosed glioblastoma: NCCTG N057K. ( Anderson, SK; Brown, PD; Buckner, JC; Flynn, PJ; Galanis, E; Giannini, C; Jaeckle, KA; Kaufmann, TJ; Ligon, KL; Ma, DJ; McGraw, S; Peller, PJ; Sarkaria, JN; Schiff, D; Uhm, JH, 2015)
"Temozolomide was given 150 mg/m(2) days 1-7 and 15-21, every 28 days for 8 cycles."2.80Efficacy and patient-reported outcomes with dose-intense temozolomide in patients with newly diagnosed pure and mixed anaplastic oligodendroglioma: a phase II multicenter study. ( Ahluwalia, MS; Brewer, C; Chamberlain, MC; Dahiya, S; Elson, P; Fisher, PG; Hashemi-Sadraei, N; Newton, HB; Pannullo, S; Peereboom, DM; Prayson, R; Schiff, D; Wood, L; Xie, H, 2015)
"The rate of dying after disease progression is about 6."2.80Variation over time and interdependence between disease progression and death among patients with glioblastoma on RTOG 0525. ( Curran, W; Dignam, JJ; Gilbert, MR; Mehta, M; Wang, M; Won, M, 2015)
"Cilengitide was administered intravenously in combination with daily temozolomide (TMZ) and concomitant radiotherapy (RT; wk 1-6), followed by TMZ maintenance therapy (TMZ/RT→TMZ)."2.80Two cilengitide regimens in combination with standard treatment for patients with newly diagnosed glioblastoma and unmethylated MGMT gene promoter: results of the open-label, controlled, randomized phase II CORE study. ( Ashby, L; Depenni, R; Fink, KL; Grujicic, D; Hegi, ME; Hicking, C; Lhermitte, B; Mazurkiewicz, M; Mikkelsen, T; Nabors, LB; Nam, DH; Perry, JR; Picard, M; Reardon, DA; Salacz, M; Tarnawski, R; Zagonel, V, 2015)
"Sorafenib (Sb) is a multiple kinase inhibitor targeting both tumour cell proliferation and angiogenesis that may further act as a potent radiosensitizer by arresting cells in the most radiosensitive cell cycle phase."2.79Phase I study of sorafenib combined with radiation therapy and temozolomide as first-line treatment of high-grade glioma. ( Ben Aissa, A; Bodmer, A; Dietrich, PY; Dunkel, N; Espeli, V; Hottinger, AF; Hundsberger, T; Mach, N; Schaller, K; Squiban, D; Vargas, MI; Weber, DC, 2014)
" There was no clear relationship between vorinostat dosage and drug exposure over the dose range studied."2.78A pediatric phase 1 trial of vorinostat and temozolomide in relapsed or refractory primary brain or spinal cord tumors: a Children's Oncology Group phase 1 consortium study. ( Ahern, C; Ames, MM; Blaney, SM; Fouladi, M; Gilbertson, RJ; Horton, T; Hummel, TR; Ingle, AM; McGovern, RM; Reid, JM; Wagner, L; Weigel, B, 2013)
"Cefixime prophylaxis was used to reduce irinotecan-associated diarrhea."2.78Pilot study of vincristine, oral irinotecan, and temozolomide (VOIT regimen) combined with bevacizumab in pediatric patients with recurrent solid tumors or brain tumors. ( Cripe, T; Geller, J; Nagarajan, R; Turpin, B; Wagner, L; Weiss, B, 2013)
"The upfront approach to treatment of glioblastoma in the unresectable population warrants further investigation in randomized controlled phase III trials."2.78Phase II trial of upfront bevacizumab and temozolomide for unresectable or multifocal glioblastoma. ( Bailey, L; Coan, A; Desjardins, A; Friedman, HS; Herndon, JE; Lipp, ES; Lou, E; Peters, KB; Reardon, DA; Sumrall, AL; Turner, S; Vredenburgh, JJ, 2013)
"Patients with multiple brain metastases from NSCLC aged ≥ 18 years, classified according to recursive partitioning analysis class I or II and with adequate organ functions were eligible."2.78Temozolomide added to whole brain radiotherapy in patients with multiple brain metastases of non-small-cell lung cancer: a multicentric Austrian phase II study. ( Altorjai, G; Dieckmann, K; Geissler, K; Hassler, MR; Knocke-Abulesz, TH; Marosi, C; Pfeifer, W, 2013)
"NSCLC patients with 1 to 3 brain metastases were randomized to receive WBRT (2."2.78A phase 3 trial of whole brain radiation therapy and stereotactic radiosurgery alone versus WBRT and SRS with temozolomide or erlotinib for non-small cell lung cancer and 1 to 3 brain metastases: Radiation Therapy Oncology Group 0320. ( Buyyounouski, MK; Demas, W; Khuntia, D; Komaki, R; Mehta, MP; Nedzi, LA; Perry, G; Robins, HI; Schell, MC; Shah, SA; Souhami, L; Sperduto, PW; Suh, JH; Wang, M; Werner-Wasik, M, 2013)
"The results suggest that Cyberknife re-treatments are relatively safe using selected dose/fraction schemes."2.77Efficacy and toxicity of CyberKnife re-irradiation and "dose dense" temozolomide for recurrent gliomas. ( Arpa, D; Cardali, S; Conti, A; De Renzis, C; Granata, F; Pontoriero, A; Romanelli, P; Siragusa, C; Tomasello, C; Tomasello, F, 2012)
"Seventy-one eligible patients 70 years of age or older with newly diagnosed GBM and a Karnofsky performance status ≥60 were treated with a short course of RT (40 Gy in 15 fractions over 3 weeks) plus TMZ at the dosage of 75 mg/m(2) per day followed by 12 cycles of adjuvant TMZ (150-200 mg/m(2) for 5 days during each 28-day cycle)."2.77Phase II study of short-course radiotherapy plus concomitant and adjuvant temozolomide in elderly patients with glioblastoma. ( Arcella, A; Caporello, P; De Sanctis, V; Enrici, RM; Giangaspero, F; Lanzetta, G; Minniti, G; Salvati, M; Scaringi, C, 2012)
"Patients with brain metastases (BM) rarely survive longer than 6months and are commonly excluded from clinical trials."2.77Outcome, quality of life and cognitive function of patients with brain metastases from non-small cell lung cancer treated with whole brain radiotherapy combined with gefitinib or temozolomide. A randomised phase II trial of the Swiss Group for Clinical Ca ( Anchisi, S; Bernhard, J; Bodis, S; Caspar, CB; Cathomas, R; D'Addario, G; Fischer, N; Klingbiel, D; Kotrubczik, NM; Mayer, M; Pesce, GA; Peters, S; Pilop, C; Pless, M; Ribi, K; Schlaeppi, M; Stupp, R; von Moos, R; Weber, DC; Zouhair, A, 2012)
"WBI alone in patients with Brain metastases (BM) from solid tumours."2.77Whole-brain irradiation with concomitant daily fixed-dose temozolomide for brain metastases treatment: a randomised phase II trial. ( Arrieta, Ó; Ferrari-Carballo, T; Gamboa-Vignolle, C; Mohar, A, 2012)
"The median number of brain metastases was 1."2.77Chemosensitized radiosurgery for recurrent brain metastases. ( Fortin, MA; Pouliot, JF; Roberge, D; Souhami, L, 2012)
" In addition, various protracted temozolomide dosing schedules have been evaluated as a strategy to further enhance its anti-tumor activity."2.76Effect of CYP3A-inducing anti-epileptics on sorafenib exposure: results of a phase II study of sorafenib plus daily temozolomide in adults with recurrent glioblastoma. ( Bigner, DD; Desjardins, A; Friedman, AH; Friedman, HS; Gururangan, S; Herndon, JE; Janney, D; Marcello, J; McLendon, RE; Peters, K; Reardon, DA; Sampson, JH; Vredenburgh, JJ, 2011)
"Vatalanib was well tolerated with only 2 DLTs (thrombocytopenia and elevated transaminases)."2.76Phase I trial with biomarker studies of vatalanib (PTK787) in patients with newly diagnosed glioblastoma treated with enzyme inducing anti-epileptic drugs and standard radiation and temozolomide. ( Batchelor, TT; Doyle, CL; Drappatz, J; Duda, DG; Eichler, AF; Gerstner, ER; Jain, RK; Plotkin, SR; Wen, PY; Xu, L, 2011)
" On the basis of promising preclinical data, the safety and tolerability of therapy with the mTOR inhibitor RAD001 in combination with radiation (RT) and temozolomide (TMZ) was evaluated in this Phase I study."2.76North Central Cancer Treatment Group Phase I trial N057K of everolimus (RAD001) and temozolomide in combination with radiation therapy in patients with newly diagnosed glioblastoma multiforme. ( Brown, PD; Buckner, JC; Galanis, E; Giannini, C; Jaeckle, KA; McGraw, S; Peller, PJ; Sarkaria, JN; Uhm, JH; Wu, W, 2011)
"The primary objective of this augmental, prospective, uncontrolled phase II multicentre trial was to assess adverse events (AE) associated with malignant glioma resection using 5-aminolevulinic (5-ALA)."2.76Favorable outcome in the elderly cohort treated by concomitant temozolomide radiochemotherapy in a multicentric phase II safety study of 5-ALA. ( Kern, BC; Krex, D; Mehdorn, HM; Nestler, U; Pichlmeier, U; Stockhammer, F; Stummer, W; Vince, GH, 2011)
" The major differences of our protocol from the other past studies were simultaneous use of both sodium borocapate and boronophenylalanine, and combination with fractionated X-ray irradiation."2.76Phase II clinical study of boron neutron capture therapy combined with X-ray radiotherapy/temozolomide in patients with newly diagnosed glioblastoma multiforme--study design and current status report. ( Hiramatsu, R; Hirota, Y; Kawabata, S; Kirihata, M; Kuroiwa, T; Maruhashi, A; Miyata, S; Miyatake, S; Ono, K; Sakurai, Y; Takekita, Y, 2011)
"Temozolomide has an acceptable tolerance in elderly patients with GBM and KPS less than 70."2.76Temozolomide in elderly patients with newly diagnosed glioblastoma and poor performance status: an ANOCEF phase II trial. ( Barrie, M; Beauchesne, P; Campello, C; Cartalat-Carel, S; Catry-Thomas, I; Chinot, O; Delattre, JY; Ducray, F; Gállego Pérez-Larraya, J; Guillamo, JS; Honnorat, J; Huchet, A; Matta, M; Mokhtari, K; Monjour, A; Taillandier, L; Tanguy, ML, 2011)
"Temozolomide was administered at a dose of 150 mg/m(2) daily for five days for the first 28-day cycle and escalated to 200 mg/m(2), during subsequent cycles."2.76A phase I trial of the farnesyl transferase inhibitor, SCH 66336, with temozolomide for patients with malignant glioma. ( Coan, AD; Desjardins, A; Friedman, AH; Friedman, HS; Herndon, JE; Peters, KB; Reardon, DA; Threatt, S; Vredenburgh, JJ, 2011)
"Glioblastoma is a highly vascularised tumour with a high expression of both vascular endothelial growth factor (VEGF) and VEGFR."2.75EORTC study 26041-22041: phase I/II study on concomitant and adjuvant temozolomide (TMZ) and radiotherapy (RT) with PTK787/ZK222584 (PTK/ZK) in newly diagnosed glioblastoma. ( Brandes, AA; Gorlia, T; Hau, P; Kros, JM; Lacombe, D; Mirimanoff, RO; Stupp, R; Tosoni, A; van den Bent, MJ, 2010)
"The treatment of patients with anaplastic oligodendroglioma (AO) has been significantly impacted by the molecular detection of loss of sequences on chromosomes 1p and 19q."2.74Temozolomide single-agent chemotherapy for newly diagnosed anaplastic oligodendroglioma. ( Anderson, J; Avedissian, R; Croteau, D; Doyle, T; Gutierrez, J; Hasselbach, L; Margolis, J; Mikkelsen, T; Paleologos, N; Schultz, L, 2009)
"Patients with primary or metastatic brain tumors had a microdialysis catheter placed in peritumoral brain tissue at the time of surgical debulking."2.74The neuropharmacokinetics of temozolomide in patients with resectable brain tumors: potential implications for the current approach to chemoradiation. ( Badie, B; Blanchard, S; Chen, M; Liu, A; Portnow, J; Synold, TW, 2009)
"Glioblastomas are notorious for resistance to therapy, which has been attributed to DNA-repair proficiency, a multitude of deregulated molecular pathways, and, more recently, to the particular biologic behavior of tumor stem-like cells."2.73Stem cell-related "self-renewal" signature and high epidermal growth factor receptor expression associated with resistance to concomitant chemoradiotherapy in glioblastoma. ( Cairncross, JG; de Tribolet, N; Delorenzi, M; Dietrich, PY; Domany, E; Gorlia, T; Hainfellner, JA; Hamou, MF; Hegi, ME; Heppner, FL; Janzer, RC; Kouwenhoven, MC; Lambiv, WL; Migliavacca, E; Murat, A; Regli, L; Shay, T; Stupp, R; Wick, W; Zimmer, Y, 2008)
"Temozolomide treatment did not affect TPM plasma concentrations in chronically treated patients."2.73Temozolomide treatment does not affect topiramate and oxcarbazepine plasma concentrations in chronically treated patients with brain tumor-related epilepsy. ( Albani, F; Baruzzi, A; Contin, M; Dinapoli, L; Fabi, A; Jandolo, B; Maschio, M; Pace, A; Zarabla, A, 2008)
"We conducted a phase I and pharmacokinetic study of the epidermal growth factor receptor (EGFR) inhibitor erlotinib as a single agent and in combination with temozolomide in children with refractory solid tumors."2.73Pediatric phase I and pharmacokinetic study of erlotinib followed by the combination of erlotinib and temozolomide: a Children's Oncology Group Phase I Consortium Study. ( Adamson, PC; Blaney, SM; Dancey, JE; Gilbertson, RJ; Hamilton, M; Ingle, AM; Jakacki, RI; Krailo, MD; Tersak, J; Voss, SD, 2008)
" PCB was administered as an oral dosage of 450 mg on days 1-2 and a total dose of 300 mg on day 3."2.73Salvage chemotherapy with procarbazine and fotemustine combination in the treatment of temozolomide treated recurrent glioblastoma patients. ( Boiardi, A; Botturi, A; Eoli, M; Falcone, C; Filippini, G; Fiumani, A; Gaviani, P; Lamperti, E; Salmaggi, A; Silvani, A, 2008)
"33 patients with brain metastases were included in the study and treated with TMZ 60 mg/m2/day (days 1-16) concomitantly with WBI (36 Gy/12 fractions given in 16 days)."2.73Phase II study of temozolomide and concomitant whole-brain radiotherapy in patients with brain metastases from solid tumors. ( Balafouta, MJ; Kolokouris, D; Kouloulias, VE; Kouvaris, JR; Miliadou, A; Papacharalampous, XN; Vlahos, LJ, 2007)
" Single-dose temozolomide at five dosage levels (267, 355, 472, 628, and 835 mg/m(2)) was given at least 6 h after completion of O(6)-benzylguanine bolus."2.73Phase I trial of single-dose temozolomide and continuous administration of o6-benzylguanine in children with brain tumors: a pediatric brain tumor consortium report. ( Boyett, JM; Broniscer, A; Danks, MK; Friedman, HS; Gajjar, A; Goldman, S; Gururangan, S; Kun, LE; MacDonald, TJ; Packer, RJ; Poussaint, TY; Stewart, CF; Wallace, D, 2007)
" CB related adverse events occurring in more than one patient were fatigue, gait disturbance, nystagmus, and confusion."2.73Convection-enhanced delivery of cintredekin besudotox (interleukin-13-PE38QQR) followed by radiation therapy with and without temozolomide in newly diagnosed malignant gliomas: phase 1 study of final safety results. ( Asher, AL; Chang, SM; Croteau, D; Grahn, AY; Husain, SR; Kunwar, S; Lang, FF; Parker, K; Puri, RK; Sampson, JH; Shaffrey, M; Sherman, JW; Vogelbaum, MA, 2007)
"Perillyl alcohol has shown to have both chemopreventive and chemotherapeutic activities in preclinical studies."2.73Preliminary results from a phase I/II study of perillyl alcohol intranasal administration in adults with recurrent malignant gliomas. ( da Fonseca, CO; Fischer, J; Futuro, D; Gattass, CR; Nagel, J; Quirico-Santos, T; Schwartsmann, G, 2008)
" The main advantages are its high oral bioavailability (almost 100% although the concentration found in the cerebrospinal fluid was approximately 20% of the plasma concentration of TMZ), its lipophilic properties, and small size that confer the ability to cross the blood-brain barrier."2.72Temozolomide: An Updated Overview of Resistance Mechanisms, Nanotechnology Advances and Clinical Applications. ( Cabeza, L; Jiménez-Luna, C; Luque, R; Melguizo, C; Ortiz, R; Perazzoli, G; Prados, J, 2021)
"GBM is the grade IV glioma brain cancer which is life-threatening to many individuals affected by this cancer."2.72Temozolomide nano enabled medicine: promises made by the nanocarriers in glioblastoma therapy. ( Shetty, K; Yadav, KS; Yasaswi, PS, 2021)
"Malignant tumors in young patients present a significant therapeutic challenge for physicians, partially due to their rarity and a relative lack of data, at least compared to adult tumors."2.72An overview of current results with the vincristine-irinotecan-temozolomide combination with or without bevacizumab in pediatric, adolescence and adult solid tumors. ( Fioretzaki, R; Kosmas, C; Papageorgiou, G; Tsakatikas, S, 2021)
"Brain metastases are a common complication in patients suffering from metastatic malignant melanoma."2.72Temozolomide with or without radiotherapy in melanoma with unresectable brain metastases. ( Budach, V; Hofmann, M; Kiecker, F; Schlenger, L; Sterry, W; Trefzer, U; Wurm, R, 2006)
"Decision making at disease progression is critical, and classical T1 and T2 imaging remain the gold standard."2.72Perfusion and diffusion MRI of glioblastoma progression in a four-year prospective temozolomide clinical trial. ( Buff, E; Leimgruber, A; Maeder, PP; Meuli, RA; Ostermann, S; Stupp, R; Yeon, EJ, 2006)
"Temozolomide (TMZ) has shown modest efficacy in the treatment of recurrent brain metastasis (BM)."2.72Vinorelbine combined with a protracted course of temozolomide for recurrent brain metastases: a phase I trial. ( Abrey, LE; Demopoulos, A; Malkin, MG; Omuro, AM; Raizer, JJ, 2006)
"Temozolomide was in general well tolerated; the most frequent side-effects were hematological."2.71Second-line chemotherapy with temozolomide in recurrent oligodendroglioma after PCV (procarbazine, lomustine and vincristine) chemotherapy: EORTC Brain Tumor Group phase II study 26972. ( Baron, B; Boogerd, W; Bravo Marques, J; Chinot, O; De Beule, N; Kros, JM; Taphoorn, MJ; van den Bent, MJ; van der Rijt, CC; Vecht, CJ, 2003)
"To construct a population pharmacokinetic model for temozolomide (TMZ), a novel imidazo-tetrazine methylating agent and its metabolites MTIC and AIC in infants and children with primary central nervous system tumors."2.71Population pharmacokinetics of temozolomide and metabolites in infants and children with primary central nervous system tumors. ( Fouladi, M; Gajjar, A; Heideman, RL; Kirstein, MN; Nair, G; Panetta, JC; Stewart, CF; Wilkinson, M, 2003)
"To characterize and compare pharmacokinetic parameters in children and adults treated with temozolomide (TMZ) administered for 5 days in three doses daily, and to evaluate the possible relationship between AUC values and hematologic toxicity."2.71Pharmacokinetics of temozolomide given three times a day in pediatric and adult patients. ( Barone, C; Caldarelli, M; Cefalo, G; Garrè, ML; Lazzareschi, I; Madon, E; Maira, G; Massimino, M; Mastrangelo, S; Mazzarella, G; Riccardi, A; Riccardi, R; Ridola, V; Ruggiero, A; Sandri, A, 2003)
"Oral ondansetron (8 mg) was given 1 h prior to temozolomide administration."2.71Dose-dense regimen of temozolomide given every other week in patients with primary central nervous system tumors. ( Abdulkarim, B; Armand, JP; Cioloca, C; Djafari, L; Djazouli, K; Faivre, S; Guillamo, JS; Osorio, M; Parker, F; Raymond, E; Vera, K, 2004)
"Temozolomide is an oral chemotherapeutic agent with efficacy against malignant gliomas and a favorable safety profile."2.71Phase II study of temozolomide without radiotherapy in newly diagnosed glioblastoma multiforme in an elderly populations. ( Barrie, M; Braguer, D; Chinot, OL; Dufour, H; Figarella-Branger, D; Frauger, E; Grisoli, F; Hoang-Xuan, K; Martin, PM; Moktari, K; Palmari, J; Peragut, JC, 2004)
"Temozolomide is a well-tolerated oral alkylating agent with activity in the CNS."2.71Temozolomide for the treatment of brain metastases associated with metastatic melanoma: a phase II study. ( Agarwala, SS; Atkins, M; Buzaid, A; Czarnetski, B; Dreno, B; Gore, M; Kirkwood, JM; Rankin, EM; Skarlos, D; Thatcher, N, 2004)
"Because of the diffuse nature of gliomatosis cerebri (GC), surgery is not suitable, and large field radiotherapy carries the risk of severe toxicity."2.71Initial chemotherapy in gliomatosis cerebri. ( Carpentier, A; Cartalat-Carel, S; Chinot, O; Cougnard, J; Delattre, JY; Djafari, L; Duffau, H; Gervais, H; Hoang-Xuan, K; Honnorat, J; Laigle, F; Mokhtari, K; Napolitano, M; Sanson, M; Taillandier, L; Taillibert, S, 2004)
"The optimal therapy for gliomatosis cerebri is unclear, and the rate of response to chemotherapy is not known."2.71Chemotherapy as initial treatment in gliomatosis cerebri: results with temozolomide. ( Gomori, JM; Levin, N; Siegal, T, 2004)
"We conducted a study to determine the dose-limiting toxicity of an extended dosing schedule of temozolomide (TMZ) when used with a fixed dose of BCNU, or 1,3-bis(2-chloroethyl)-1-nitrosourea (carmustine), taking advantage of TMZ's ability to deplete O6-alkylguanine-DNA-alkyltransferase and the synergistic activity of these two agents."2.71Phase 1 study of 28-day, low-dose temozolomide and BCNU in the treatment of malignant gliomas after radiation therapy. ( Abrey, LE; Kleber, M; Malkin, MG; Raizer, JJ, 2004)
"Temozolomide is an oral alkylating agent that can cross the blood-brain barrier and in phase II and III trials, patients with advanced metastatic melanoma achieved overall response rates of 13 to 21%."2.71The effect of temozolomide-based chemotherapy in patients with cerebral metastases from melanoma. ( Bafaloukos, D; Briassoulis, E; Christodoulou, C; Fountzilas, G; Gogas, H; Hatzichristou, H; Kalofonos, HP; Linardou, H; Panagiotou, P; Tsoutsos, D, 2004)
"Temozolomide was administered starting the first day of RT at 150 mg/m(2) daily for 5 days every 4 weeks for the first cycle and escalated to a maximum dose of 200 mg/m(2)."2.71Phase II study of temozolomide and thalidomide with radiation therapy for newly diagnosed glioblastoma multiforme. ( Chang, SM; Lamborn, KR; Larson, D; Malec, M; Nicholas, MK; Page, M; Prados, MD; Rabbitt, J; Sneed, P; Wara, W, 2004)
"To evaluate the efficacy of temozolomide (TMZ) combined with cisplatin (CDDP) in terms of response rate, time to progression (TTP) and overall survival (OS), as well as the tolerability of the regimen in patients with brain metastases from solid tumors."2.71Temozolomide (TMZ) combined with cisplatin (CDDP) in patients with brain metastases from solid tumors: a Hellenic Cooperative Oncology Group (HeCOG) Phase II study. ( Aravantinos, G; Bafaloukos, D; Bamias, A; Carina, M; Christodoulou, C; Klouvas, G; Linardou, H; Skarlos, D, 2005)
"Temozolomide was administered orally each therapy day at a dose of 50 mg/m(2)."2.71Temozolomide combined with irradiation as postoperative treatment of primary glioblastoma multiforme. Phase I/II study. ( Combs, SE; Debus, J; Edler, L; Gutwein, S; Schulz-Ertner, D; Thilmann, C; van Kampen, M; Wannenmacher, MM, 2005)
"Temozolomide was administered orally at 150 mg/mq/day for five consecutive days for the first cycle, doses were increased to 200 mg/mq/day for 5 days every 28 days for subsequent cycles if no grade 3/4 haematological toxicity was observed."2.71Oral temozolomide in heavily pre-treated brain metastases from non-small cell lung cancer: phase II study. ( Blanco, G; Bordonaro, R; Castorina, S; Failla, G; Giorgio, CG; Giuffrida, D; Pappalardo, A; Russo, A; Salice, P; Santini, D, 2005)
"Temozolomide is an oral alkylating agent that has equivalent activity to dacarbazine, but it has the advantage of CNS penetration."2.71A phase II study of biochemotherapy for advanced melanoma incorporating temozolomide, decrescendo interleukin-2 and GM-CSF. ( Anderson, C; Baron, A; Gibbs, P; Gonzalez, R; Lewis, KD; O'Day, S; Richards, J; Russ, P; Weber, J; Zeng, C, 2005)
"Fifty-two patients with brain metastases from solid tumors were randomized to oral temozolomide (75 mg/m(2)/d) concurrent with 40-Gy fractionated conventional external-beam radiotherapy (2 Gy, 5 d/wk) for 4 weeks versus 40-Gy radiotherapy alone."2.70Phase II randomized trial of temozolomide and concurrent radiotherapy in patients with brain metastases. ( Antonadou, D; Coliarakis, N; Economou, I; Karageorgis, P; Paraskevaidis, M; Sarris, G; Throuvalas, N, 2002)
"Temozolomide is a new cytotoxic alkylating agent that has recently been approved in Portugal for the treatment of recurrent high-grade glioma."2.70Temozolomide in second-line treatment after prior nitrosurea-based chemotherapy in glioblastoma multiforme: experience from a Portuguese institution. ( Albano, J; Cernuda, M; Garcia, I; Lima, L; Oliveira, C; Portela, I; Teixeira, MM, 2002)
"Treatment with temozolomide was well tolerated."2.70Phase II study of temozolomide in heavily pretreated cancer patients with brain metastases. ( Bacoyiannis, C; Bafaloukos, D; Bamias, A; Christodoulou, C; Karabelis, A; Kosmidis, P; Papakostas, P; Samantas, E; Skarlos, DV, 2001)
"Eight children with poor prognosis brain tumors were eligible."2.70Concomitant radiotherapy and metronomic temozolomide in pediatric high-risk brain tumors. ( Pavelka, Z; Slampa, P; Sterba, J, 2002)
" The absolute bioavailability of TMZ was 0."2.69Pharmacokinetics of temozolomide in association with fotemustine in malignant melanoma and malignant glioma patients: comparison of oral, intravenous, and hepatic intra-arterial administration. ( Bauer, J; Biollaz, J; Buclin, T; Decosterd, LA; Gander, M; Lejeune, F; Leyvraz, S; Marzolini, C; Shen, F, 1998)
"Fotemustine 100 mg/m2 was given intravenously on day 2, 4 hours after TMZ."2.69Sequential administration of temozolomide and fotemustine: depletion of O6-alkyl guanine-DNA transferase in blood lymphocytes and in tumours. ( Belanich, M; Biollaz, J; Bonfanti, M; Colella, G; D'Incalci, M; Decosterd, L; Gander, M; Lejeune, F; Leyvraz, S; Liénard, D; Marzolini, C; Perey, L; Shen, F; Yarosh, D, 1999)
" Temozolomide demonstrated linear and reproducible pharmacokinetics and was rapidly absorbed (mean Tmax approximately 1 h) and eliminated (mean t1/2 = 1."2.69Phase I dose-escalation and pharmacokinetic study of temozolomide (SCH 52365) for refractory or relapsing malignancies. ( Batra, V; Beale, P; Brada, M; Cutler, D; Dugan, M; Judson, I; Moore, S; Reidenberg, P; Statkevich, P, 1999)
"Temozolomide was well tolerated with little subjective toxicity and usually predictable myelosuppression and is a promising new drug in the treatment of primary brain tumours."2.67Temozolomide: a new oral cytotoxic chemotherapeutic agent with promising activity against primary brain tumours. ( Brampton, M; Colquhoun, IR; Glaser, MG; Illingworth, RD; Kennard, C; Lewis, P; Newlands, ES; O'Reilly, SM; Rice-Edwards, JM; Richards, PG, 1993)
"Glioblastoma is the most common primary malignant brain tumor."2.66MGMT Status as a Clinical Biomarker in Glioblastoma. ( Aldape, K; Butler, M; Pommier, Y; Pongor, L; Quezado, M; Raffeld, M; Su, YT; Trepel, J; Wu, J; Xi, L, 2020)
"Glioblastoma is the most common malignant primary brain tumor."2.66Management of glioblastoma: State of the art and future directions. ( Ashley, DM; Friedman, HS; Khasraw, M; López, GY; Malinzak, M; Tan, AC, 2020)
"Brain tissue necrosis (treatment necrosis [TN]) as a consequence of brain directed cancer therapy remains an insufficiently characterized condition with diagnostic and therapeutic difficulties and is frequently associated with significant patient morbidity."2.61Treatment-induced brain tissue necrosis: a clinical challenge in neuro-oncology. ( Batchelor, TT; Dietrich, J; Loebel, F; Loeffler, J; Martinez-Lage, M; Vajkoczy, P; Winter, SF, 2019)
"Glioblastoma (GBM), the most common primary brain tumor, is the most aggressive human cancers, with a median survival rate of only 14."2.61Aberrant Transcriptional Regulation of Super-enhancers by RET Finger Protein-histone Deacetylase 1 Complex in Glioblastoma: Chemoresistance to Temozolomide. ( Aoki, K; Hirano, M; Natsume, A; Ranjit, M; Wakabayashi, T, 2019)
"Temozolomide (TMZ) is an antiangiogenic agent."2.58Opposite Interplay Between the Canonical WNT/β-Catenin Pathway and PPAR Gamma: A Potential Therapeutic Target in Gliomas. ( Guillevin, R; Lecarpentier, Y; Vallée, A; Vallée, JN, 2018)
"The approach to treat glioblastoma has not suffered major changes over the last decade and temozolomide (TMZ) remains the mainstay for chemotherapy."2.58Repurposing drugs for glioblastoma: From bench to bedside. ( Basso, J; Miranda, A; Pais, A; Sousa, J; Vitorino, C, 2018)
"Glioblastomas are rich in blood vessels (i."2.58Anti-angiogenic therapy for high-grade glioma. ( Ameratunga, M; Grant, R; Khasraw, M; Pavlakis, N; Simes, J; Wheeler, H, 2018)
"Temozolomide may cause thrombocytopenia or neutropenia in 3-4% of glioblastoma patients, respectively."2.55MGMT gene variants, temozolomide myelotoxicity and glioma risk. A concise literature survey including an illustrative case. ( Altinoz, MA; Bolukbasi, FH; Ekmekci, CG; Elmaci, I; Sari, R; Sav, A; Yenmis, G, 2017)
"The standard treatment for brain metastases is radiotherapy."2.55Combined treatment for non-small cell lung cancer and breast cancer patients with brain metastases with whole brain radiotherapy and temozolomide: a systematic review and meta-analysis. ( Luo, Y; Tang, J; Tian, J; Xiang, J, 2017)
"Glioblastoma is the most common primary CNS malignancy and it is becoming more frequently diagnosed in the elderly population."2.55Glioblastoma in the elderly: initial management. ( de Moraes, FY; Laperriere, N, 2017)
" This review summarizes the mechanism of action, efficacy, and adverse events based on pre-clinical studies and clinical trials for TTF in GBM."2.55Tumor treating fields: a novel and effective therapy for glioblastoma: mechanism, efficacy, safety and future perspectives. ( Zhu, JJ; Zhu, P, 2017)
"The tumor, a grade 3 anaplastic oligodendroglioma, was excised, and chemoradiotherapy was administered."2.55Regression of Recurrent High-Grade Glioma with Temozolomide, Dexamethasone, and Levetiracetam: Case Report and Review of the Literature. ( Abraham Koshy, A; Kumar A, A, 2017)
"Glioblastoma is the most common and most aggressive form of primary brain tumor in adults and contributes to high social and medical burden as a result of its incurable nature and significant neurologic morbidity."2.55Treatment of Glioblastoma. ( de Groot, JF; Nam, JY, 2017)
"Fibrosarcoma is a rare brain tumour with 33 cases reported so far."2.53Intracranial fibrosarcoma treated with adjuvant radiation and temozolomide: Report of a case and review of all published cases. ( Giridhar, P; Gupta, S; Haresh, KP; Julka, PK; Mallick, S; Rath, GK, 2016)
"Glioblastoma is the most common and the most lethal primary brain tumor in adults."2.53Guidelines, "minimal requirements" and standard of care in glioblastoma around the Mediterranean Area: A report from the AROME (Association of Radiotherapy and Oncology of the Mediterranean arEa) Neuro-Oncology working party. ( , 2016)
"Glioblastoma is almost always incurable and most older patients survive less than 6 months."2.53How I treat glioblastoma in older patients. ( Mohile, NA, 2016)
"To enhance the benefit of TMZ in the treatment of glioblastomas, effective combination strategies are needed to sensitize glioblastoma cells to TMZ."2.53Targeting autophagy to sensitive glioma to temozolomide treatment. ( Dai, S; Gong, Z; Qian, L; Sun, L; Xu, Z; Yan, Y, 2016)
"Glioblastoma is a unique model of non-metastasising disease that kills the vast majority of patients through local growth, despite surgery and local irradiation."2.53Therapeutic interactions of autophagy with radiation and temozolomide in glioblastoma: evidence and issues to resolve. ( Giatromanolaki, A; Koukourakis, MI; Mitrakas, AG, 2016)
"Anaplastic oligodendrogliomas have long attracted interest because of their sensitivity to chemotherapy, in particular in the subset of 1p/19q co-deleted tumors."2.53Low-grade and anaplastic oligodendroglioma. ( Bromberg, JE; Buckner, J; Van Den Bent, MJ, 2016)
"889 with respect to OS, while BEV in combination with TMZ - with a probability of 0."2.53A network meta-analysis: the overall and progression-free survival of glioma patients treated by different chemotherapeutic interventions combined with radiation therapy (RT). ( Ding, L; Gao, L; Lv, P; Qi, L; Wang, S; Wang, W; Xu, Y; Zhao, D; Zhong, Y, 2016)
"Glioblastoma is a malignant tumor of astrocytic origin that is highly invasive, proliferative and angiogenic."2.53Microglia in Cancer: For Good or for Bad? ( Amaral, R; da Fonseca, AC; Garcia, C; Geraldo, LH; Lima, FR; Matias, D, 2016)
"Temozolomide (TMZ) is a DNA-methylating agent."2.53Current and Future Drug Treatments for Glioblastomas. ( Hirose, Y; Ohba, S, 2016)
" Patients aged over 70 years with favorable KPS, or patients aged 60-70 years with borderline KPS, should be considered for monotherapy utilizing standard TMZ dosing for patients with MGMT-methylated tumors, and hypofractionated RT (34 Gy in ten fractions or 40 Gy in 15 fractions) for patients with MGMT-unmethylated tumors."2.50Treatment options and outcomes for glioblastoma in the elderly patient. ( Arvold, ND; Reardon, DA, 2014)
"The incidence of brain metastases from breast cancer is increasing with diagnosis and therapeutics progress, especially with systemic therapies."2.50[Radiotherapy plus concomitant systemic therapies for patients with brain metastases from breast cancer]. ( Cao, KI; Kirova, YM, 2014)
"Glioblastoma is the most aggressive primary brain tumor in adults."2.50Predictive biomarkers investigated in glioblastoma. ( Chinot, O; Delattre, JY; Hoang-Xuan, K; Idbaih, A; Loundou, A; Sanson, M; Tabouret, E, 2014)
"Gliomas are the most frequent primary brain tumors."2.50[Management of gliomas]. ( Chapet, S; Lévy, S; Mazeron, JJ, 2014)
"Brain metastases are associated with substantial morbidity and mortality."2.50Treatment of brain metastases. ( Chmura, SJ; Gabikian, P; Garza, M; Lukas, RV, 2014)
"Glioblastoma is the most common malignant brain tumor in adults and carries a particularly poor prognosis."2.50Glioblastoma survival: has it improved? Evidence from population-based studies. ( Barnholtz-Sloan, JS; Bauchet, L; Woehrer, A, 2014)
"Glioblastoma multiforme is the most common and most lethal pri- mary malignant tumor of the central nervous system."2.50Astrocytoma malignum in glioblastoma multiforme vertens with long term survival--case report and a literature review. ( Bochenek-Cibor, J; Krupa, M; Moskała, M; Trojanowski, T, 2014)
"Abstract: Anaplastic oligodendroglioma (AO) is a rare malignant tumor occurring in adults."2.49Treatment recommendations for anaplastic oligodendrogliomas that are codeleted. ( Anderson, MD; Gilbert, MR, 2013)
"Many physicians are reluctant to treat elderly glioblastoma (GBM) patients as aggressively as younger patients, which is not evidence based due to the absence of validated data from primary studies."2.49Radiotherapy plus concurrent or sequential temozolomide for glioblastoma in the elderly: a meta-analysis. ( Cheng, JX; Dong, Y; Han, N; Liu, BL; Yin, AA; Zhang, LH; Zhang, X, 2013)
"Gliomas are the most frequent primary brain tumors in adults."2.49High-grade glioma in elderly patients: can the oncogeriatrician help? ( Chinot, O; Crétel, E; Retornaz, F; Rousseau, F; Tabouret, E; Tassy, L, 2013)
"Temozolomide (TMZ) was first known to be useful as a radiosensitiser in both primary brain tumours like glioblastoma multiforme and oligodendroglioma."2.49Temozolomide and unusual indications: review of literature. ( Abrial, C; Durando, X; Gadea, E; Gimbergues, P; Planchat, E; Tatar, Z; Thivat, E, 2013)
"Brain metastases affect 37% of patients suffering from metastatic melanoma, and their prognosis remains poor, with an overall survival lower than six months."2.49[Therapeutic strategies and systemic treatment of brain melanoma metastases]. ( Brocard, L; Daste, A; Durando, X; Gimbergues, P; Magné, N; Mansard, S; Thivat, E, 2013)
" Hematotoxicity is listed as a frequent adverse drug reaction in the US prescribing information and hepatotoxicity has been reported infrequently in the postmarketing period."2.48Severe sustained cholestatic hepatitis following temozolomide in a patient with glioblastoma multiforme: case study and review of data from the FDA adverse event reporting system. ( Bronder, E; Garbe, E; Herbst, H; Kauffmann, W; Klimpel, A; Orzechowski, HD; Sarganas, G; Thomae, M, 2012)
"Ganglioneuroblastoma is a rare tumor variant of neuroblastoma."2.48Cerebral ganglioneuroblastoma of adult onset: two patients and a review of the literature. ( Kloet, A; Schipper, MH; Taphoorn, MJ; van Duinen, SG; Vecht, CJ; Walchenbach, R; Wiggenraad, RG, 2012)
"Glioblastoma is the most frequent primary malignant brain tumor in adults."2.48Integrin inhibitor cilengitide for the treatment of glioblastoma: a brief overview of current clinical results. ( Caporello, P; Enrici, RM; Minniti, G; Scaringi, C, 2012)
"For the treatment of brain metastases from NSCLC, the combined therapy of WBRT plus TMZ improves OR, but without significant improvement in OS."2.48[Whole brain radiation therapy plus temozolomide in the treatment of brain metastases from non small cell lung cancer: a meta-analysis]. ( Bi, ZF; He, Y; Liao, K; Liu, YM, 2012)
"Angiocentric gliomas have recently been reclassified as a separate central nervous system tumor."2.48Imaging characteristics of an unusual, high-grade angiocentric glioma: a case report and review of the literature. ( Aguilar, HN; Hung, RW; Kotylak, T; Mehta, V, 2012)
"Temozolomide (TMZ) is a DNA-alkylating agent used for the treatment of glioma, astrocytoma, and melanoma."2.47A novel approach to overcome temozolomide resistance in glioma and melanoma: Inactivation of MGMT by gene therapy. ( Jiang, G; Liu, YQ; Pei, DS; Wei, ZP; Xin, Y; Zheng, JN, 2011)
"Medical treatment of brain metastases (BM) is still a controversial issue in cancer therapy being mainly limited by the existence of the BBB."2.47Combining temozolomide with other antitumor drugs and target-based agents in the treatment of brain metastases: an unending quest or chasing a chimera? ( Addeo, R; Caraglia, M, 2011)
"Temozolomide (TMZ) is an oral alkylating agent with activity in high and LGG."2.47Using different schedules of Temozolomide to treat low grade gliomas: systematic review of their efficacy and toxicity. ( Athanasiou, T; Lashkari, HP; Moreno, L; Saso, S; Zacharoulis, S, 2011)
" These may include TMZ concentrations in the brain parenchyma, TMZ dosing schemes, hypoxic microenvironments, niche factors, and the re-acquisition of stem cell properties by non-stem cells."2.47Chemoresistance of glioblastoma cancer stem cells--much more complex than expected. ( Beier, CP; Beier, D; Schulz, JB, 2011)
"Temozolomide is a second-generation alkylating chemotherapeutic agent, introduced to therapy of primary brain tumors in the 1990s."2.46Temozolomide: Expanding its role in brain cancer. ( Adair, J; Kiem, HP; Mrugala, MM, 2010)
"Temozolomide is a new drug which has shown promise in treating malignant gliomas and other difficult-to-treat tumors."2.45Temozolomide with radiation therapy in high grade brain gliomas: pharmaceuticals considerations and efficacy; a review article. ( Beli, I; Chaldeopoulos, D; Fotineas, A; Koukourakis, GV; Kouloulias, V; Kouvaris, J; Maravelis, G; Pantelakos, P; Papadimitriou, C; Zacharias, G, 2009)
"Temozolomide is an oral alkylating cytotoxic agent of second generation, used in the treatment of high-grade gliomas."2.45[Prescription guidebook for temozolomide usage in brain tumors]. ( Borget, I; Brignone, M; Cartalat-Carel, S; Chinot, O; Hassani, Y; Taillandier, L; Taillibert, S; Tilleul, P, 2009)
"Temozolomide (TMZ) is an oral alkylating agent that is regarded as a tolerable and effective drug."2.45Temozolomide in malignant gliomas: current use and future targets. ( Bressler, LR; Seery, TE; Villano, JL, 2009)
" Alternative dosing regimens, such as 1-week on/1-week off, or 3-week on/1-week off, that deliver more prolonged exposure have been observed to result in higher cumulative doses than the standard 5-day regimen and may deplete tumor-derived O6-methylguanine-DNA methyltransferase (MGMT) in tumor cells, thus sensitizing tumor cells to the effects of TMZ."2.45[Treatment of glioma with temozolomide]. ( Nishikawa, R, 2009)
" Several preliminary studies have been initiated to address the issue of resistance and suppression of MGMT activity, and have used alternative temozolomide dosing schedules and O(6)-guanine mimetic agents as substrates for MGMT."2.44Mechanisms of disease: temozolomide and glioblastoma--look to the future. ( Chamberlain, MC; Mrugala, MM, 2008)
"Anaplastic astrocytoma is an uncommon disease in the adult population."2.44Anaplastic astrocytoma in adults. ( Gatta, G; Mazza, E; Reni, M; Stupp, R; Vecht, C, 2007)
"Temozolomide is an alkylating agent used frequently in the management of gliomas."2.44Prolonged and severe myelosuppression in two patients after low-dose temozolomide treatment- case study and review of literature. ( Brown, MP; Selva-Nayagam, S; Singhal, N, 2007)
"Glioma is a highly invasive, rapidly spreading form of brain cancer that is resistant to surgical and medical treatment."2.44Potential biochemical therapy of glioma cancer. ( Fan, XJ; Fu, YJ; Liang, AH; Liu, ZL; Xu, CG; Xu, QL; Yang, J; Yin, LT, 2007)
"Temozolomide has proven benefit in grade II/III gliomas progressive following standard therapy and when added to radiation for glioblastoma."2.44Temozolomide and radiation in low-grade and anaplastic gliomas: temoradiation. ( Schiff, D, 2007)
"Temozolomide (TMZ) has emerged as an active agent against malignant gliomas."2.44Management of glioblastoma. ( Aoki, T; Hashimoto, N; Matsutani, M, 2007)
"High-grade glioma is a devastating disease that leaves the majority of its victims dead within 2 years."2.44Carmustine wafers: localized delivery of chemotherapeutic agents in CNS malignancies. ( Kleinberg, LR; Lin, SH, 2008)
"Additionally, there is evidence that treatment-related necrosis occurs more frequently and earlier after temozolomide chemotherapy than after radiotherapy alone."2.44Clinical features, mechanisms, and management of pseudoprogression in malignant gliomas. ( Brandsma, D; Sminia, P; Stalpers, L; Taal, W; van den Bent, MJ, 2008)
"Leptomeningeal dissemination of juvenile pilocytic astrocytoma (JPA) is a rare event."2.43Management of pilocytic astrocytoma with diffuse leptomeningeal spread: two cases and review of the literature. ( Aryan, HE; Bruce, DA; Levy, ML; Lu, DC; Meltzer, HS; Ozgur, BM, 2005)
"Temozolomide (TMZ) is a promising new drug that seems to be effective in patients with recurrent disease."2.43Adjuvant chemotherapy in the treatment of high grade gliomas. ( Brandes, AA; Lonardi, S; Tosoni, A, 2005)
"Temozolomide (TMZ) is an alkylating agent that was approved for anaplastic astrocytoma and glioblastoma."2.43Optimal role of temozolomide in the treatment of malignant gliomas. ( Hegi, ME; Stupp, R; van den Bent, MJ, 2005)
"Astrocytomas are the most common primary brain tumors."2.43Treatment of astrocytomas. ( Gilbert, MR; Gonzalez, J, 2005)
"Glioblastomas are the most frequent and the most aggressive primary brain tumors in adults."2.43[Concomitant radiotherapy with chemotherapy in patients with glioblastoma]. ( Benouaich-Amiel, A; Delattre, JY; Simon, JM, 2005)
"The prognosis for patients with malignant primary brain tumors has been poor, and until recently, there was little evidence that chemotherapy was beneficial."2.43Advances in the treatment of primary brain tumors: dawn of a new era? ( Gilbert, MR, 2006)
"Temozolomide (TMZ) is an alkylating agent earlier approved for recurrent anaplastic astrocytoma and approved for the treatment of newly diagnosed glioblastoma in the USA and Europe in 2005."2.43Temozolomide: a milestone in the pharmacotherapy of brain tumors. ( Steinbach, JP; Weller, M; Wick, W, 2005)
" TMZ is able to cross the blood brain barrier and is stable at gastric acid pH so it has almost 100% oral bioavailability and is rapidly absorbed after it is taken orally."2.43Role of temozolomide in pediatric brain tumors. ( Barone, G; Maurizi, P; Riccardi, R; Tamburrini, G, 2006)
"Brain metastases from renal cell carcinoma (RCC) cause significant morbidity and mortality."2.43Radiation therapy in the management of brain metastases from renal cell carcinoma. ( Amato, R; Doh, LS; Paulino, AC; Teh, BS, 2006)
"Glioblastoma multiforme is the most common primary brain tumor in adults."2.43Drug Insight: temozolomide as a treatment for malignant glioma--impact of a recent trial. ( Cairncross, JG; Mason, WP, 2005)
"Irinotecan is a water-soluble derivative of camptothecin, an alkylator originally extracted from the Chinese tree Camptotheca acuminata."2.42The emerging role of irinotecan (CPT-11) in the treatment of malignant glioma in brain tumors. ( Friedman, HS; Houghton, PJ; Keir, ST, 2003)
"First-line chemotherapy for brain metastases or with only minor neurological signs and symptoms, and who have an indication for systematic chemotherapy for metastases elsewhere in the body."2.42The role of chemotherapy in brain metastases. ( van den Bent, MJ, 2003)
"The incidence of oligodendroglioma is increasing, most likely due to its improved recognition."2.42Oligodendroglioma and anaplastic oligodendroglioma: clinical features, treatment, and prognosis. ( Engelhard, HH; Mundt, A; Stelea, A, 2003)
"Temozolomide has activity and a favorable safety profile in all dosing schedules tested."2.42Temozolomide: realizing the promise and potential. ( Dolan, ME; Nagasubramanian, R, 2003)
"As long as metastasis is confined to one organ system and is removable, surgery remains the treatment of first choice."2.42[Therapy of malignant melanoma at the stage of distant metastasis]. ( Eigentler, TK; Garbe, C, 2004)
"Melanoma is the third most common metastatic brain tumor in the United States and is a major cause of morbidity and mortality."2.42Management of brain metastases in patients with melanoma. ( Agarwala, SS; Tarhini, AA, 2004)
"Brain metastases are a major clinical challenge and usually signify very poor prognosis for most patients."2.42Treatment of brain metastases: a short review of current therapies and the emerging role of temozolomide. ( Abrey, LE; Mehta, MP, 2003)
"Temozolomide is an imidazotetrazine with a mechanism of action and efficacy similar to dacarbazine (DTIC)."2.41Temozolomide: a novel oral alkylating agent. ( Danson, SJ; Middleton, MR, 2001)
" The drug is well tolerated with dose limiting myelosuppression and thrombocytopenia occurring in less than 10% of patients at current dosage schedules."2.41The use of temozolomide in recurrent malignant gliomas. ( Gaya, A; Greenstein, A; Rees, J; Stebbing, J, 2002)
"Metastatic brain tumors are the most common complication of systemic cancer and affect 20-40% of all adult cancer patients."2.41Chemotherapy for the treatment of metastatic brain tumors. ( Newton, HB, 2002)
"Temozolomide was effective in delaying disease progression and maintaining health-related quality of life."2.41Temozolomide in malignant gliomas. ( Yung, WK, 2000)
"Temozolomide is a novel, oral, second-generation alkylating agent."2.41Temozolomide in early stages of newly diagnosed malignant glioma and neoplastic meningitis. ( Friedman, HS, 2000)
"Temozolomide, a new drug, has shown promise in treating malignant gliomas and other difficult-to-treat tumors."2.41Temozolomide and treatment of malignant glioma. ( Calvert, H; Friedman, HS; Kerby, T, 2000)
"Temozolomide appears to produce few serious adverse effects and may also have a positive impact on health-related quality of life."2.41A rapid and systematic review of the effectiveness of temozolomide for the treatment of recurrent malignant glioma. ( Cave, C; Dinnes, J; Huang, S; Milne, R, 2002)
"Moreover, the efficacy of the treatment of glioma cells with temozolomide (TMZ) and Gli1 inhibitor GANT61 was higher than that of TMZ alone."1.91Differential role of Pax6 and its interaction with Shh-Gli1-IDH2 axis in regulation of glioma growth and chemoresistance. ( Ahmed, SP; Ali, A; Arif, SH; Chosdol, K; Farheen, S; Hoda, MF; Kausar, T; Mariyath P M, M; Nayeem, SM; Shahi, MH, 2023)
"Glioblastoma (GBM) is a fast-growing primary brain tumor characterized by high invasiveness and resistance."1.91Targeting integrin α2 as potential strategy for radiochemosensitization of glioblastoma. ( Cordes, N; Korovina, I; Temme, A; Vehlow, A, 2023)
" However, poor site-specific delivery and bioavailability significantly restrict the efficient permeability of regorafenib to brain lesions and compromise its treatment efficacy."1.91Brain-Targeted HFn-Cu-REGO Nanoplatform for Site-Specific Delivery and Manipulation of Autophagy and Cuproptosis in Glioblastoma. ( Ding, N; Huang, C; Jia, W; Jiang, J; Li, L; Luo, M; Nice, EC; Tian, H; Zhang, H; Zhou, L, 2023)
"Temozolomide was successfully up-titrated to the full dose."1.91Safe administration of temozolomide in end-stage renal disease patients. ( Hundal, J; Pereira, MK; Singh, A; Vredenburg, J, 2023)
"Glioblastoma is the most common primary malignant tumor of the central nervous system."1.91Comparative Study of Extremely Low-Frequency Electromagnetic Field, Radiation, and Temozolomide Administration in Spheroid and Monolayer Forms of the Glioblastoma Cell Line (T98). ( Ahmadi-Zeidabadi, M; Amirinejad, M; Jomehzadeh, A; Khoei, S; Kordestani, Z; Larizadeh, MH; Yahyapour, R, 2023)
"Glioblastoma (GBM) is the most lethal primary brain tumor in adults and harbors a subpopulation of glioma stem cells (GSCs)."1.91EZH2 interacts with HP1BP3 to epigenetically activate WNT7B that promotes temozolomide resistance in glioblastoma. ( Li, M; Tian, W; Wang, B; Wang, Y; Xu, R; Yu, T; Zeng, A; Zhang, J; Zhou, F; Zhou, Z, 2023)
"Gliomas are one of the most common primary malignant tumors of the central nervous system, and have an unfavorable prognosis."1.91Role of COL6A2 in malignant progression and temozolomide resistance of glioma. ( Hong, X; Ouyang, J; Peng, X; Wang, P; Xiao, B; Zhang, J; Zou, J, 2023)
"Glioblastoma is among the most lethal cancers, with no known cure."1.91A high-density 3-dimensional culture model of human glioblastoma for rapid screening of therapeutic resistance. ( Bhatt, H; Brown, JMC; Gray, WP; Ormonde, C; Sharouf, F; Siebzehnrubl, FA; Spencer, R; Zaben, M, 2023)
" The primary endpoints were skin, neurological and psychiatric adverse events."1.91Safety and efficacy of tumour-treating fields (TTFields) therapy for newly diagnosed glioblastoma in Japanese patients using the Novo-TTF System: a prospective post-approval study. ( Arakawa, Y; Kanamori, M; Mukasa, A; Muragaki, Y; Narita, Y; Nishikawa, R; Tanaka, S; Yamaguchi, S; Yamasaki, F, 2023)
"Gliosarcoma is a histopathological variant of glioblastoma, which is characterized by a biphasic growth pattern consisting of glial and sarcoma components."1.91Prognostic Factors of Gliosarcoma in the Real World: A Retrospective Cohort Study. ( Shen, J; Song, K; Wei, L; Xu, H; Xu, M; Yu, Z; Zhou, Z; Zhu, W, 2023)
" Safety was determined by the number of treatment-related adverse events."1.91Antisecretory factor is safe to use as add-on treatment in newly diagnosed glioblastoma. ( Belting, M; Bengzon, J; Cederberg, D; Darabi, A; Edvardsson, C; Ehinger, E; Kopecky, J; Siesjö, P; Tomasevic, G; Visse, E, 2023)
"Glioblastoma (GBM) is the most frequent brain cancer and more lethal than other cancers."1.91Erythrose inhibits the progression to invasiveness and reverts drug resistance of cancer stem cells of glioblastoma. ( Agredano-Moreno, LT; Gallardo-Pérez, JC; Jimenez-García, LF; López-Marure, R; Robledo-Cadena, DX; Sánchez-Lozada, LG; Trejo-Solís, MC, 2023)
"High-grade gliomas (HGG) are aggressive brain tumors associated with short median patient survival and limited response to therapies, driving the need to develop tools to improve patient outcomes."1.91The development of a rapid patient-derived xenograft model to predict chemotherapeutic drug sensitivity/resistance in malignant glial tumors. ( Brochu-Gaudreau, K; Charbonneau, M; Dubois, CM; Fortin, D; Harper, K; Lucien, F; Perreault, A; Roy, LO; Tian, S, 2023)
" Based on the genetic testing results, almonertinib combined with anlotinib and temozolomide was administered and obtained 12 months of progression-free survival after the diagnosis of recurrence as the fourth-line treatment."1.91Almonertinib Combined with Anlotinib and Temozolomide in a Patient with Recurrent Glioblastoma with EGFR L858R Mutation. ( Dong, S; Hou, Z; Li, S; Luo, N; Tao, R; Wu, H; Zhang, H; Zhang, X; Zhu, D, 2023)
"Temozolomide (TMZ) is a first line agent used in the clinic for glioblastoma and it has been useful in increasing patient survival rates."1.91Efficient delivery of Temozolomide using ultrasmall large-pore silica nanoparticles for glioblastoma. ( Ahmed-Cox, A; Akhter, DT; Cao, Y; Fletcher, NL; Janjua, TI; Kavallaris, M; Moniruzzaman, M; Popat, A; Raza, A; Thurecht, KJ, 2023)
"Glioblastoma is the most common malignant brain tumor in adults."1.91Influence of MMR, MGMT Promotor Methylation and Protein Expression on Overall and Progression-Free Survival in Primary Glioblastoma Patients Treated with Temozolomide. ( Birkl-Toeglhofer, AM; Brawanski, KR; Freyschlag, CF; Haybaeck, J; Hoeftberger, R; Manzl, C; Sprung, S; Ströbel, T; Thomé, C, 2023)
"Temozolomide (TMZ) is a chemotherapy agent used to treat primary central nervous system tumors."1.91Metastatic Melanoma: A Preclinical Model Standardization and Development of a Chitosan-Coated Nanoemulsion Containing Temozolomide to Treat Brain Metastasis. ( Azambuja, JH; Braganhol, E; de Cássia Sant'ana, R; de Souza, PO; Debom, GN; Fachel, FNS; Gelsleichter, NE; Lenz, GS; Michels, LR; Roliano, GG; Teixeira, FC; Teixeira, HF; Visioli, F, 2023)
" In this paper, we present the effects of juglone alone and in combination with temozolomide on glioblastoma cells."1.91Juglone in Combination with Temozolomide Shows a Promising Epigenetic Therapeutic Effect on the Glioblastoma Cell Line. ( Barciszewska, AM; Belter, A; Gawrońska, I; Giel-Pietraszuk, M; Naskręt-Barciszewska, MZ, 2023)
"Glioblastoma (GBM) is an incurable primary brain tumor with a poor prognosis."1.91Acetogenins-Rich Fractions of ( Alexandre, GP; Arantes, A; Junqueira, JGM; Kim, B; Oliveira, AGS; Reis, RM; Ribeiro, RIMA; Severino, VGP; Sousa, LR, 2023)
"Temozolomide (TMZ) treatment is the mainstay drug for GBM despite the rapid development of resistance in mesenchymal GBM."1.91NADPH Oxidase Subunit CYBB Confers Chemotherapy and Ferroptosis Resistance in Mesenchymal Glioblastoma via Nrf2/SOD2 Modulation. ( Fong, IH; Lin, CM; Liu, HW; Setiawan, SA; Su, IC; Su, YK; Yadav, VK; Yeh, CT, 2023)
"Temozolomide has been mainly used for the treatment of malignant gliomas over a decade."1.91[Medical Treatments for Malignant Brain Tumor]. ( Kitamura, Y; Toda, M, 2023)
"Temozolomide (TMZ) is a standard chemotherapeutic for GBM, but TMZ treatment benefits are compromised by chemoresistance."1.91Identification of the E2F1-RAD51AP1 axis as a key factor in MGMT-methylated GBM TMZ resistance. ( Cui, X; Kang, C; Liu, X; Tong, F; Wang, G; Wang, Q; Wang, Y; Zhao, J; Zhou, J, 2023)
"Glioblastoma is the most aggressive and fatal form of brain cancer."1.91The antagonistic effects of temozolomide and trichostatin a combination on MGMT and DNA mismatch repair pathways in Glioblastoma. ( Castresana, JS; Denizler-Ebiri, FN; Güven, M; Taşpınar, F; Taşpınar, M, 2023)
"New approaches to the treatment of glioblastoma, including immune checkpoint blockade and oncolytic viruses, offer the possibility of improving glioblastoma outcomes and have as such been under intense study."1.91Agent-Based Modelling Reveals the Role of the Tumor Microenvironment on the Short-Term Success of Combination Temozolomide/Immune Checkpoint Blockade to Treat Glioblastoma. ( Craig, M; Fiset, B; Jenner, AL; Karimi, E; Quail, DF; Surendran, A; Walsh, LA, 2023)
" The most common adverse events were leukocytopenia (66."1.91Safety and Efficacy of Anlotinib Hydrochloride Plus Temozolomide in Patients with Recurrent Glioblastoma. ( Bu, L; Cai, J; Chen, Q; Huang, K; Meng, X; Weng, Y; Xu, Q; Zhan, R; Zhang, L; Zheng, X, 2023)
"GBM (Glioblastoma) is the most lethal CNS (Central nervous system) tumor in adults, which inevitably develops resistance to standard treatments leading to recurrence and mortality."1.91TRIB1 confers therapeutic resistance in GBM cells by activating the ERK and Akt pathways. ( Becker, AP; Becker, V; Bell, EH; Chakravarti, A; Cui, T; Fleming, JL; Grosu, AL; Han, C; Haque, SJ; Johnson, B; Kumar, A; Manring, HR; McElroy, J; Meng, X; Robe, PA; Schrock, MS; Sebastian, E; Showalter, CA; Singh, K; Summers, MK; Tong, ZY; Venere, M, 2023)
"Neuroblastoma is the most common tumour in children under 1 year old, accounting for 12-15% of childhood cancer deaths."1.91Autophagy Inhibition via Hydroxychloroquine or 3-Methyladenine Enhances Chemotherapy-Induced Apoptosis in Neuro-Blastoma and Glioblastoma. ( Balachandar, A; Bhagirath, E; Pandey, S; Vegh, C; Wear, D, 2023)
"Temozolomide (TMZ) was given to 24 patients and 11 patients received TMZ plus other chemotherapies."1.91The effect of chemotherapies on the crosstalk interaction between CD8 cytotoxic T-cells and MHC-I peptides in the microenvironment of WHO grade 4 astrocytoma. ( Alkhayyat, S; Alkhotani, A; Almansouri, M; Alshanqiti, M; Alsinani, T; Baeesa, S; Bamaga, AK; Butt, N; Enani, M; Fadul, MM; Faizo, E; Hassan, A; Karami, MM; Kurdi, M, 2023)
"Mismatch repair-deficient (MMRD) brain tumors are rare among primary brain tumors and can be induced by germline or sporadic mutations."1.72Sporadic and Lynch syndrome-associated mismatch repair-deficient brain tumors. ( Choi, SH; Kang, J; Kim, H; Kim, SK; Kim, TM; Lee, K; Lim, KY; Park, CK; Park, JW; Park, SH; Shim, Y; Won, JK; Yun, H, 2022)
"Allopregnanolone (allo) is a physiological regulator of neuronal activity that treats multiple neurological disorders."1.72Allopregnanolone suppresses glioblastoma survival through decreasing DPYSL3 and S100A11 expression. ( Feng, YH; Hsu, SP; Hsu, TI; Kao, TJ; Ko, CY; Lim, SW; Lin, HY; Wang, SA, 2022)
"Glioblastoma (GBM) is the most lethal primary brain tumor."1.72Novel Imidazotetrazine Evades Known Resistance Mechanisms and Is Effective against Temozolomide-Resistant Brain Cancer in Cell Culture. ( Berry, MR; Fan, TM; Hergenrother, PJ; Kelly, AM; McKee, SA; Svec, RL, 2022)
"The incidence of gliomas is increasing."1.72CCL2 activates AKT signaling to promote glycolysis and chemoresistance in glioma cells. ( Ding, P; Lu, B; Nie, X; Qian, Y; Xu, J, 2022)
"Since high grade gliomas are aggressive brain tumors, intensive search for new treatment options is ongoing."1.72Tumor treating fields therapy is feasible and safe in a 3-year-old patient with diffuse midline glioma H3K27M - a case report. ( Dohmen, H; Gött, H; Kiez, S; Kolodziej, M; Stein, M, 2022)
"Glioblastoma multiforme (GBM) is a primary brain tumor with devastating prognosis."1.72Recycling of SLC38A1 to the plasma membrane by DSCR3 promotes acquired temozolomide resistance in glioblastoma. ( Huang, G; Lin, R; Liu, Y; Ni, B; Qi, ST; Song, H; Wang, H; Wang, Z; Xie, S; Xu, Y; Yi, GZ; Zhang, Y, 2022)
" Therefore, localised approaches that treat GB straight into the tumour site provide an alternative to enhance chemotherapy bioavailability and efficacy, reducing systemic toxicity."1.72Nek1-inhibitor and temozolomide-loaded microfibers as a co-therapy strategy for glioblastoma treatment. ( Arantes, PR; Borges, GR; Braganhol, E; Dalanhol, CS; de Barros Dias, MCH; de Oliveira Merib, J; de Souza, PO; Ferro, MB; Henn, JG; Morás, AM; Moura, DJ; Nugent, M; Reinhardt, LS, 2022)
"Glioblastomas are the most aggressive brain tumors for which therapeutic options are limited."1.72Anti-glioblastoma effects of phenolic variants of benzoylphenoxyacetamide (BPA) with high potential for blood brain barrier penetration. ( Carson, SC; Colley, SB; Faia, C; Ingraham Iv, CH; Jursic, BS; Lassak, A; Peruzzi, F; Plaisance-Bonstaff, K; Reiss, K; Stalinska, J; Vittori, C, 2022)
"Temozolomide (TMZ) is a DNA alkylating agent that appears to have a radiosensitizing effect when used in combination with RT and may be worthwhile in meningioma treatment."1.72Concomitant Temozolomide plus radiotherapy for high-grade and recurrent meningioma: a retrospective chart review. ( Belanger, K; Damek, D; Lillehei, KO; Ormond, DR; Ung, TH, 2022)
"Glioma is the most common and malignant brain tumor with poor prognosis."1.72LINC01564 Promotes the TMZ Resistance of Glioma Cells by Upregulating NFE2L2 Expression to Inhibit Ferroptosis. ( Li, X; Luo, C; Nie, C; Qian, K; Wang, X; Zeng, Y, 2022)
"Temozolomide use was affected by age, performance and MGMT promoter (all P < 0."1.72Current trend of radiotherapy for glioblastoma in the elderly: a survey study by the brain tumor Committee of the Korean Radiation Oncology Group (KROG 21-05). ( In Yoon, H; Lee, SW; Lim, DH; Wee, CW, 2022)
"Glioma is one of the main causes of cancer-related mortality worldwide and is associated with high heterogeneity."1.72Tryptophan hydroxylase 1 drives glioma progression by modulating the serotonin/L1CAM/NF-κB signaling pathway. ( Gao, X; Guo, Z; Xie, Q; Yang, Q; Zhang, J; Zhong, C, 2022)
" Additionally, by lowering the effective dosage of TMZ, the combination liposomes reduced systemic TMZ-induced toxicity, highlighting the preclinical potential of this novel integrative strategy to deliver combination therapies to brain tumors."1.72Targeted liposomes for combined delivery of artesunate and temozolomide to resistant glioblastoma. ( Chai, T; Du, Q; Hanif, S; Ismail, M; Li, Y; Muhammad, P; Shi, B; Yang, W; Zhang, D; Zheng, M, 2022)
"Temozolomide (TMZ) is a widely used chemotherapeutic drug for glioma."1.72FOXM1-mediated NUF2 expression confers temozolomide resistance to human glioma cells by regulating autophagy via the PI3K/AKT/mTOR signaling pathway. ( Guo, L; Wu, Z, 2022)
" Non-ionising electromagnetic fields represent an emerging option given the potential advantages of safety, low toxicity and the possibility to be combined with other therapies."1.72Selective cell cycle arrest in glioblastoma cell lines by quantum molecular resonance alone or in combination with temozolomide. ( Astori, G; Belli, R; Bernardi, M; Bozza, A; Catanzaro, D; Celli, P; Chieregato, K; Menarin, M; Merlo, A; Milani, G; Peroni, D; Pozzato, A; Pozzato, G; Raneri, FA; Ruggeri, M; Volpin, L, 2022)
"Temozolomide (TMZ) is a chemotherapeutic drug for the treatment of GBM."1.72Temozolomide increases heat shock proteins in extracellular vesicles released from glioblastoma cells. ( Adıgüzel, Z; Kıyga, E; Önay Uçar, E, 2022)
"Glioblastoma multiforme is a malignant neoplasia with a median survival of less than two years and without satisfactory therapeutic options."1.72The role of Shikonin in improving 5-aminolevulinic acid-based photodynamic therapy and chemotherapy on glioblastoma stem cells. ( Buchner, A; Lyu, C; Pohla, H; Schrader, I; Sroka, R; Stadlbauer, B; Stepp, H; Werner, M, 2022)
"Temozolomide (TMZ) is a first-line chemotherapeutic agent for glioblastoma, but the emergence of drug resistance limits its anti-tumor activity."1.72GBP3 promotes glioblastoma resistance to temozolomide by enhancing DNA damage repair. ( Chen, CC; Chen, Y; Grigore, FN; Jin, J; Lan, Q; Li, M; Li, S; Ma, J; Wang, J; Wang, Q; Wu, G; Xu, H; Zhu, H, 2022)
"Metformin is a biguanide drug utilized as the first-line medication in treating type 2 diabetes."1.72Exploring the Mechanism of Adjuvant Treatment of Glioblastoma Using Temozolomide and Metformin. ( Chang, PC; Chen, HY; Feng, SW; Huang, SM; Hueng, DY; Li, YF, 2022)
"Gliomas are the most common type of primary brain tumors, with high recurrence rate and mortality."1.72ZNF300 enhances temozolomide resistance in gliomas by regulating lncRNA SNHG12. ( Fu, J; Peng, J; Tu, G, 2022)
"Temozolomide-based treatment was administered to 64 of 68 (94."1.72Early Postoperative Treatment versus Initial Observation in CNS WHO Grade 2 and 3 Oligodendroglioma: Clinical Outcomes and DNA Methylation Patterns. ( Aichholzer, M; Berghoff, AS; Dieckmann, K; Furtner, J; Goldberger, S; Hatziioannou, T; Heller, G; Leibetseder, A; Mair, MJ; Pichler, J; Preusser, M; Puhr, R; Tomasich, E; von Oertzen, T; Weis, S; Widhalm, G; Wöhrer, A, 2022)
"After surgical treatment, glioblastoma (GBM) patients require prompt therapy within 14 days in a patient-specific manner."1.72Tissue Niche Miniature of Glioblastoma Patient Treated with Nano-Awakeners to Induce Suicide of Cancer Stem Cells. ( Baek, S; Chang, JH; Choi, RJ; Jo, E; Kang, SG; Kim, EH; Lee, D; Lee, JB; Moon, JH; Park, J; Park, JS; Shim, JK; Sung, HJ; Yoon, SJ; Yu, SE, 2022)
"Glioblastoma is a malignant primary brain tumor that affects approximately 250,000 new patients per year worldwide."1.72Current therapeutic options for glioblastoma and future perspectives. ( Aquilanti, E; Wen, PY, 2022)
"Apatinib is a multitarget tyrosine kinase inhibitor, which has been reported to exhibit broad antitumor profiles."1.72Apatinib and temozolomide in children with recurrent ependymoma: A case report. ( Li, J; Shen, Z; Shi, L; Zhang, N; Zhao, S, 2022)
"Temozolomide (TMZ) is a first-line clinical chemotherapeutic drug."1.72Piperlongumine-inhibited TRIM14 signaling sensitizes glioblastoma cells to temozolomide treatment. ( Chen, KC; Chen, PH; Ho, KH; Kuo, YY; Liu, AJ; Shih, CM, 2022)
"Glioblastoma is the most common brain tumor."1.72 ( Balkanov, AS; Belyaev, AY; Glazkov, AA; Kobyakov, GL; Rozanov, ID; Shmakov, PN; Strunina, YV; Telysheva, EN; Usachev, DY, 2022)
"Glioma is a fatal tumor originating from the brain, which accounts for most intracranial malignancies."1.72SLC11A1 as a stratification indicator for immunotherapy or chemotherapy in patients with glioma. ( Fang, C; Liu, Y; Lou, M; Shao, A; Wang, W; Wang, X; Xu, H; Xu, Y; Yuan, L; Zhang, A; Zhang, Z; Zhu, Q, 2022)
"Glioma is a common type of malignant and aggressive tumor in the brain."1.72Elevated GIGYF2 expression suppresses tumor migration and enhances sensitivity to temozolomide in malignant glioma. ( Chen, M; Feng, W; Li, J; Li, M; Li, T; Liu, Y; Xia, X; Yang, W; Yuan, Q; Zhang, S; Zhou, X; Zuo, M, 2022)
" The efficacy and optimal deployment schedule of the orally bioavailable small-molecule tumor checkpoint controller lisavanbulin alone, and in combination with, standards of care were assessed using a panel of IDH-wildtype GBM patient-derived xenografts."1.72Preclinical modeling in glioblastoma patient-derived xenograft (GBM PDX) xenografts to guide clinical development of lisavanbulin-a novel tumor checkpoint controller targeting microtubules. ( Bachmann, F; Bakken, KK; Burgenske, DM; Carlson, BL; Decker, PA; Eckel-Passow, JE; Elmquist, WF; Gampa, G; Giannini, C; He, L; Hu, Z; Kitange, GJ; Kosel, ML; Lane, HA; McSheehy, P; Mladek, AC; Pokorny, JL; Sarkaria, JN; Schmitt-Hoffmann, A; Schroeder, MA; Talele, S; Vaubel, RA, 2022)
"Malignant gliomas are the most common brain tumors, with generally dismal prognosis, early clinical deterioration and high mortality."1.62Non-alkylator anti-glioblastoma agents induced cell cycle G2/M arrest and apoptosis: Design, in silico physicochemical and SAR studies of 2-aminoquinoline-3-carboxamides. ( Gu, X; Liu, J; Ni, X; Qi, Y; Qian, X; Shao, X; Xu, X; Yuan, P, 2021)
"Glioma is the most common and malignant primary brain tumour in adults and has a dismal prognosis."1.62Accurately Controlled Delivery of Temozolomide by Biocompatible UiO-66-NH ( Chen, H; Gu, J; Jiang, J; Li, C; Li, Y; Luo, C; Qian, J; Wan, Z; Wang, J; Zhu, J, 2021)
"The highly lethal brain cancer glioblastoma (GBM) poses a daunting challenge because the blood-brain barrier renders potentially druggable amplified or mutated oncoproteins relatively inaccessible."1.62Targeting glioblastoma signaling and metabolism with a re-purposed brain-penetrant drug. ( Armando, AM; Bi, J; Cloughesy, TF; Cravatt, BF; Curtis, EJ; Furnari, FB; Gimple, RC; Gu, Y; Jing, H; Khan, A; Koga, T; Kornblum, HI; Miki, S; Mischel, PS; Prager, B; Quehenberger, O; Reed, A; Rich, JN; Rzhetsky, A; Tang, J; Wainwright, DA; Wong, IT; Wu, S; Yang, H; Zhang, W, 2021)
"Glioma is the most common primary intracranial tumor."1.62FXYD2 mRNA expression represents a new independent factor that affects survival of glioma patients and predicts chemosensitivity of patients to temozolomide. ( Huang, L; Jiang, T; Li, G; Liu, Y; Zhao, Z; Zhou, K, 2021)
"Temozolomide is an alkylating agent most commonly used with a few other second line options."1.62Nanomedicine in the treatment of Glioblastoma. ( Bukhari, SS; Kishwar Jafri, SK; Shamim, MS, 2021)
" Furthermore, the non-cytolytic and non-cytotoxic metronomic dosage of hydroxyurea and temozolomide had increased the DBM therapy outcome by strengthening anti-tumor capability."1.62A retrospective observational study on cases of anaplastic brain tumors treated with the Di Bella Method: A rationale and effectiveness. ( Borghetto, V; Costanzo, E; Di Bella, G, 2021)
"Brain cancer is a devastating disease given its extreme invasiveness and intricate location."1.62Gradient hydrogels for screening stiffness effects on patient-derived glioblastoma xenograft cellfates in 3D. ( Grant, GA; Li, J; Trinh, P; Yang, F; Zhu, D, 2021)
" The aim of this study was to introduce the Z-scan technique as a fast, accurate, inexpensive, and safe in vitro method to distinguish the cytotoxic effects of various treatments."1.62Z-scan method to measure the nonlinear optical behavior of cells for evaluating the cytotoxic effects of chemotherapy and hyperthermia treatments. ( Ara, MHM; Ardakani, AA; Asgari, H; Ghader, A; Khoei, S; Minaei, SE, 2021)
"Temozolomide (TMZ) has been used to treat glioma."1.62Circ-VPS18 Knockdown Enhances TMZ Sensitivity and Inhibits Glioma Progression by MiR-370/RUNX1 Axis. ( Jia, X; Li, W; Liu, Q; Ma, Q; Wang, X; Yan, P, 2021)
"Glioblastoma multiforme is a malignant central nervous system (CNS) disease with dismal prognosis."1.62Notable response of a young adult with recurrent glioblastoma multiforme to vincristine-irinotecan-temozolomide and bevacizumab. ( Fioretzaki, RG; Kosmas, C; Papageorgiou, GI; Tsakatikas, SA, 2021)
"Glioblastoma multiforme is one of the most common malignant types of tumor arising from the central nervous system known for its devastating intracranial progress and dismal prognosis."1.62FDG PET/CT in Recurrent Glioblastoma Multiforme With Leptomeningeal and Diffuse Spinal Cord Metastasis. ( Malik, D, 2021)
"Glioblastoma is a highly malignant brain tumor with limited treatment options and short survival times."1.62Drug repurposing using transcriptome sequencing and virtual drug screening in a patient with glioblastoma. ( Efferth, T; Giordano, FA; Greten, HJ; Kadioglu, O; Mayr, K; Saeed, MEM; Wenz, F; Yildirim, A, 2021)
"GBM (glioblastoma multiforme) is the most common and aggressive brain tumor."1.62Regorafenib in glioblastoma recurrence: A case report. ( Desideri, I; Detti, B; Ganovelli, M; Greto, D; Livi, L; Lorenzetti, V; Lucidi, S; Maragna, V; Scoccianti, S; Scoccimarro, E; Teriaca, MA, 2021)
"Temozolomide (TMZ) has been widely used as a first-line treatment for GBM."1.62Intranasal Delivery of Temozolomide-Conjugated Gold Nanoparticles Functionalized with Anti-EphA3 for Glioblastoma Targeting. ( Li, N; Li, Y; Lv, Y; Sha, C; Sun, K; Tang, S; Wang, A; Wang, L; Yan, X; Yu, Y, 2021)
"In this work, we constructed LPHNs-cRGD for targeting delivery of the CRISPR/Cas9 system, in combination with FUS-MBs to open the BBB."1.62Gene Therapy for Drug-Resistant Glioblastoma via Lipid-Polymer Hybrid Nanoparticles Combined with Focused Ultrasound. ( Chen, J; Cheng, Y; Huang, N; Wang, Z; Yang, Q; Zhou, Y, 2021)
"Canine glioma is a common brain tumor with poor prognosis despite surgery and/or radiation therapy."1.62The NRG3/ERBB4 signaling cascade as a novel therapeutic target for canine glioma. ( Akiyoshi, H; Ichikawa, T; Inoue, M; Kamishina, H; Kurozumi, K; Matsumoto, Y; Nakamoto, Y; Noguchi, S, 2021)
" However, clinical trials show that treatment schedule and drug dosage significantly affect patient survival."1.62A neuro evolutionary algorithm for patient calibrated prediction of survival in Glioblastoma patients. ( Ebrahimi Zade, A; Shahabi Haghighi, S; Soltani, M, 2021)
"Glioblastoma multiforme is the most aggressive and lethal form of brain tumour due to the high degree of cancer cells infiltration into surrounding brain tissue."1.62Bioresorbable, electrospun nonwoven for delayed and prolonged release of temozolomide and nimorazole. ( Janeczek, H; Karpeta-Jarząbek, P; Kasperczyk, J; Musiał-Kulik, M; Pastusiak, M; Stojko, M; Włodarczyk, J, 2021)
"Temozolomide (TMZ) is an effective chemotherapy drug for glioblastoma, but the resistance to TMZ has come to represent a major clinical problem, and its underlying mechanism has yet to be elucidated."1.62Exosomal connexin 43 regulates the resistance of glioma cells to temozolomide. ( Bi, QC; Gan, LJ; Han, XJ; Hong, T; Jiang, LP; Lan, XM; Liu, LH; Tan, RJ; Wei, MJ; Yang, ZJ; Zhang, LL, 2021)
"Glioblastoma is the most malignant brain tumor and presents high resistance to chemotherapy and radiotherapy."1.62APR-246 combined with 3-deazaneplanocin A, panobinostat or temozolomide reduces clonogenicity and induces apoptosis in glioblastoma cells. ( Castresana, JS; De La Rosa, J; Idoate, MA; Meléndez, B; Rey, JA; Urdiciain, A; Zazpe, I; Zelaya, MV, 2021)
"Glioblastoma is the most common primary brain tumor and remains uniformly fatal, highlighting the dire need for developing effective therapeutics."1.62Nanocell-mediated delivery of miR-34a counteracts temozolomide resistance in glioblastoma. ( Boockvar, J; Brahmbhatt, H; Gao, S; Gonzalez, C; Jamil, E; Khan, MB; MacDiarmid, J; Mugridge, N; Ruggieri, R; Sarkaria, JN; Symons, M; Tran, NL, 2021)
"Glioblastoma is a primary brain cancer with a near 100% recurrence rate."1.62De novo purine biosynthesis is a major driver of chemoresistance in glioblastoma. ( Ahmed, AU; Ali, ES; Atashi, F; Baisiwala, S; Ben-Sahra, I; Horbinski, CM; James, CD; Kumthekar, P; Lee, G; Lesniak, MS; Miska, J; Park, CH; Saathoff, MR; Savchuk, S; Shireman, JM; Stupp, R, 2021)
"Celecoxib and 2,5-DMC were the most cytotoxic."1.62COXIBs and 2,5-dimethylcelecoxib counteract the hyperactivated Wnt/β-catenin pathway and COX-2/PGE2/EP4 signaling in glioblastoma cells. ( Kleszcz, R; Krajka-Kuźniak, V; Kruhlenia, N; Majchrzak-Celińska, A; Misiorek, JO; Przybyl, L; Rolle, K, 2021)
"Differentiating treatment necrosis from tumor recurrence poses a diagnostic conundrum for many clinicians in neuro-oncology."1.62Role of circulating tumor cell detection in differentiating tumor recurrence from treatment necrosis of brain gliomas. ( Cui, Y; Gao, F; Jiang, H; Li, M; Lin, S; Ren, X; Zhao, W, 2021)
"Temozolomide (TMZ) is an alkylating agent widely used for glioma treatment."1.62miR-23b-5p promotes the chemosensitivity of temozolomide via negatively regulating TLR4 in glioma. ( Cui, B; Gao, K; Qiao, Y; Wang, T, 2021)
"Glioma is the most common malignant tumor of the brain in adult patients."1.62Molecular Characterization of AEBP1 at Transcriptional Level in Glioma. ( Huang, R; Sun, S; Tong, X; Wang, K; Wang, Z; Wu, C, 2021)
"Glioblastoma is a highly malignant brain tumor with no curative treatment options, and immune checkpoint blockade has not yet shown major impact."1.62Treating ICB-resistant glioma with anti-CD40 and mitotic spindle checkpoint controller BAL101553 (lisavanbulin). ( Bachmann, F; Dietrich, PY; Espinoza, FI; Genoud, V; Lane, HA; Marinari, E; McSheehy, P; Rochemont, V; Walker, PR, 2021)
"Temozolomide was labeled with [11C], and serial PET-MRI scans were performed in patients with recurrent GBM treated with bevacizumab and daily temozolomide."1.56Bevacizumab Reduces Permeability and Concurrent Temozolomide Delivery in a Subset of Patients with Recurrent Glioblastoma. ( Batchelor, T; Beers, AL; Catana, C; Chang, K; Dietrich, J; Duda, DG; Emblem, KE; Gerstner, ER; Hooker, JM; Jain, RK; Kalpathy-Cramer, J; Plotkin, SR; Rosen, B; Vakulenko-Lagun, B; Yen, YF, 2020)
"Perampanel (PER) is a noncompetitive α-amino-3-hydroxy-5-methyl-4-isoaxazolepropionate acid receptor antagonist that has recently been approved for treating focal epilepsy as a secondary drug of choice."1.56Experience of Low Dose Perampanel to Add-on in Glioma Patients with Levetiracetam-uncontrollable Epilepsy. ( Chonan, M; Kanamori, M; Nakasato, N; Osawa, SI; Saito, R; Suzuki, H; Tominaga, T; Watanabe, M, 2020)
"Glioblastoma is the most frequent and lethal primary brain tumor."1.56Genomic and Phenotypic Characterization of a Broad Panel of Patient-Derived Xenografts Reflects the Diversity of Glioblastoma. ( Berens, ME; Burns, TC; Califano, A; Carlson, BL; Caron, A; Decker, PA; Dhruv, HD; Eckel-Passow, JE; Evers, L; Giannini, C; Grove, R; Jenkins, RB; Kitange, GJ; Klee, EW; Kollmeyer, TM; LaChance, DH; Ma, DJ; Marin, BM; Meyer, FB; Mladek, AC; O'Neill, BP; Parney, IF; Peng, S; Remonde, D; Sarkar, G; Sarkaria, JN; Schroeder, MA; Sulman, EP; Tian, S; Tran, NL; Vaubel, RA; Verhaak, RG; Wang, Q; Yan, H, 2020)
" Because the free drug cannot pass the blood-brain barrier (BBB), we investigated the use of nanocarriers for transport of the drug through the BBB and its efficacy when combined with radiotherapy and temozolomide (TMZ) in glioma spheroids."1.56Preclinical evaluation of binimetinib (MEK162) delivered via polymeric nanocarriers in combination with radiation and temozolomide in glioma. ( Becerril Aragon, G; Bikhezar, F; de Kruijff, RM; de Vries, HE; Denkova, AG; Gasol Garcia, A; Narayan, RS; Slotman, BJ; Sminia, P; Torrelo Villa, G; van der Meer, AJGM; van der Pol, SMA, 2020)
"We identified the preoperative seizure frequency threshold by plotting a receiver operating characteristic curve."1.56Short-term outcomes and predictors of post-surgical seizures in patients with supratentorial low-grade gliomas. ( Chen, Q; Deng, G; Gao, L; Jiang, H; Liu, B; Tan, Y; Wang, J; Yang, K; Yuan, F, 2020)
"Glioblastoma is the most common primary tumor of the central nervous system that develops chemotherapy resistance."1.56Overexpression miR-486-3p Promoted by Allicin Enhances Temozolomide Sensitivity in Glioblastoma Via Targeting MGMT. ( Chen, J; Chen, L; Hao, B; He, M; Li, X; Wang, C; Wu, H; Zhang, G; Zhang, T, 2020)
"Calpeptin could inhibit the effect."1.56Calpain suppresses cell growth and invasion of glioblastoma multiforme by producing the cleavage of filamin A. ( Cai, L; Li, Q; Li, W; Lu, X; Su, Z; Tu, M; Wang, C; Zhu, Z, 2020)
"Temozolomide (TMZ) is an effective drug for prolonging the overall survival time of patients, while drug-resistance is an important clinical problem at present."1.56A steroidal saponin form Paris vietnamensis (Takht.) reverses temozolomide resistance in glioblastoma cells via inducing apoptosis through ROS/PI3K/Akt pathway. ( Fang, F; Ji, Y; Li, H; Lu, Y; Qiu, P; Tang, H; Zhang, S, 2020)
"The prognosis of glioma is generally poor and is the cause of primary malignancy in the brain."1.56MicroRNA-155-3p promotes glioma progression and temozolomide resistance by targeting Six1. ( Chen, G; Chen, Z; Zhao, H, 2020)
"Niacin treatment of mice bearing intracranial BTICs increased macrophage/microglia representation within the tumor, reduced tumor size, and prolonged survival."1.56Control of brain tumor growth by reactivating myeloid cells with niacin. ( Bose, P; Dunn, JF; Kelly, J; Mirzaei, R; Mishra, MK; Poon, C; Rawji, K; Sarkar, S; Yang, R; Yong, VW; Zemp, FJ, 2020)
"Glioma is a common cancer that affects people worldwide with high morbidity and mortality."1.56miR-149 rs2292832 C allele enhances the cytotoxic effect of temozolomide against glioma cells. ( Guo, J; Ling, G; Liu, Q; Luo, J; Luo, X; Ning, X; Xu, B, 2020)
"In adults, glioma is the most commonly occurring and invasive brain tumour."1.56CDK4/6 inhibition suppresses tumour growth and enhances the effect of temozolomide in glioma cells. ( Cao, Y; Kong, S; Li, X; Qi, Y; Shang, S, 2020)
"Trametinib has a strong anti-proliferative effect on established GB cell lines, stem cell-like cells and their differentiated progeny and while it does not enhance anti-proliferative and cell death-inducing properties of the standard treatment, i."1.56The limitations of targeting MEK signalling in Glioblastoma therapy. ( Debatin, KM; Hadzalic, A; Halatsch, ME; Karpel-Massler, G; Payer, C; Schuster, A; Selvasaravanan, KD; Siegelin, MD; Strobel, H; Westhoff, MA; Wiederspohn, N, 2020)
"Glioblastoma is the most devastating primary brain tumor and effective therapies are not available."1.56CD73 as a target to improve temozolomide chemotherapy effect in glioblastoma preclinical model. ( Azambuja, JH; Battastini, AMO; Beckenkamp, LR; Braganhol, E; de Oliveira, FH; Gelsleichter, NE; Lenz, GS; Michels, LR; Schuh, RS; Stefani, MA; Teixeira, HF; Wink, MR, 2020)
"Osthole was the most effective."1.56Coumarins modulate the anti-glioma properties of temozolomide. ( Bądziul, D; Jakubowicz-Gil, J; Langner, E; Maciejczyk, A; Rzeski, W; Skalicka-Woźniak, K; Sumorek-Wiadro, J; Wertel, I; Zając, A, 2020)
"The studies on the treatment of brain metastases from esophageal cancer by radiotherapy combined with temozolomide (TMZ) are even rarer."1.56Brain metastases from esophageal cancer: A case report. ( Cui, G; Li, N; Liu, C; Liu, M; Qie, S; Ran, Y; Sun, W; Sun, X; Tian, Y; Yang, H, 2020)
"Gliomas are intrinsic brain tumours, which are classified by the World Health Organization (WHO) into different grades of malignancy, with glioblastoma being the most frequent and most malignant subtype (WHO grade IV)."1.56A contemporary perspective on the diagnosis and treatment of diffuse gliomas in adults. ( Hofer, S; Hottinger, AF; Hundsberger, T; Läubli, H; Mamot, C; Pesce, G; Reinert, M; Roelcke, U; Roth, P; Schucht, P; Weller, M, 2020)
"Glioblastoma is devastating cancer with a high frequency of occurrence and poor survival rate and it is urgent to discover novel glioblastoma-specific antigens for the therapy."1.56Suppressing Dazl modulates tumorigenicity and stemness in human glioblastoma cells. ( Liu, C; Liu, R; Lu, Y; Zhang, F; Zhang, H, 2020)
"The major difficulty in treating glioblastoma stems from the intrinsic privileged nature of the brain."1.56Vascularized Temporoparietal Fascial Flap: A Novel Surgical Technique to Bypass the Blood-Brain Barrier in Glioblastoma. ( Abrams, M; Anderson, T; Boockvar, JA; D'Amico, R; Faltings, L; Filippi, CG; Fralin, S; Khatri, D; Langer, DJ; Li, M; Patel, NV; Ratzon, F; Reichman, N; Wong, T, 2020)
"Temozolomide chemotherapy was an independent index to prolong overall survival in high ABCC8 mRNA expression glioma patients, whereas in patients with low expression, there was no significant difference."1.56ABCC8 mRNA expression is an independent prognostic factor for glioma and can predict chemosensitivity. ( Chai, R; Huang, L; Jiang, T; Li, G; Liu, Y; Wang, Y; Zhao, Z; Zhou, K, 2020)
"Oligodendroglioma is defined by IDH mutation and 1p/19q codeletion."1.56Comparative molecular analysis of primary and recurrent oligodendroglioma that acquired imbalanced 1p/19q codeletion and TP53 mutation: a case report. ( Kamataki, A; Nanjo, H; Ono, T; Reinhardt, A; Shimizu, H; Takahashi, M; von Deimling, A, 2020)
"Glioma is one of the most aggressive forms of brain tumor and is hallmarked by high rate of mortality, metastasis and drug resistance."1.56Downregulation of hsa_circ_0000936 sensitizes resistant glioma cells to temozolomide by sponging miR-1294. ( Feng, H; Hua, L; Huang, L; Zhang, X, 2020)
"Temozolomide (TMZ) is an oral chemotherapy drug constituting the backbone of chemotherapy regimens utilized as first-line treatment of GBM."1.56LncRNA NEAT1 promotes malignant phenotypes and TMZ resistance in glioblastoma stem cells by regulating let-7g-5p/MAP3K1 axis. ( Bi, CL; Fang, JS; Lan, S; Liu, JF; Yang, ZY; Zhang, MY, 2020)
"Glioma is the most malignant tumour of the human brain still lacking effective treatment modalities."1.56Synthetic Betulin Derivatives Inhibit Growth of Glioma Cells ( Bębenek, E; Boryczka, S; Dmoszyńska-Graniczka, M; Król, SK; Stepulak, A; Sławińska-Brych, A, 2020)
"Glioblastoma (GBM) is a lethal type of primary brain tumor with a median survival less than 15 months."1.56Loss of PLK2 induces acquired resistance to temozolomide in GBM via activation of notch signaling. ( Alafate, W; Bai, X; Ma, X; Wang, J; Wang, M; Wu, W; Xiang, J; Xie, W; Xu, D, 2020)
"Glioblastoma is the most frequent aggressive primary brain tumor amongst human adults."1.56Unraveling response to temozolomide in preclinical GL261 glioblastoma with MRI/MRSI using radiomics and signal source extraction. ( Arús, C; Candiota, AP; Julià-Sapé, M; Ledesma-Carbayo, MJ; Núñez, LM; Romero, E; Santos, A; Vellido, A, 2020)
"Glioblastoma multiforme (GBM) is a primary brain tumor with a very high degree of malignancy and is classified by WHO as a glioma IV."1.56Comparison of Elemental Anomalies Following Implantation of Different Cell Lines of Glioblastoma Multiforme in the Rat Brain: A Total Reflection X-ray Fluorescence Spectroscopy Study. ( Chwiej, J; Drozdz, A; Janeczko, K; Janik-Olchawa, N; Matusiak, K; Ostachowicz, B; Planeta, K; Ryszawy, D; Setkowicz, Z, 2020)
"Glioblastoma is a severe type of brain tumor with a poor prognosis and few therapy options."1.56Revealing Temozolomide Resistance Mechanisms via Genome-Wide CRISPR Libraries. ( Andrade Tomaz, M; de Souza, I; Karolynne Seregni Monteiro, L; Menck, CFM; Molina Silva, M; Reily Rocha, A; Rocha, CRR; Rodrigues Gomes, L; Teatin Latancia, M, 2020)
"Metformin has been linked to improve survival of patients with various cancers."1.56Use of metformin and outcome of patients with newly diagnosed glioblastoma: Pooled analysis. ( Chinot, O; Genbrugge, E; Gorlia, T; Hau, P; Nabors, B; Seliger, C; Stupp, R; Weller, M, 2020)
"Palbociclib treatment significantly reduced tumorigenesis in TMZ-R/HMC3 bearing mice and SNHG15 and CDK6 expression was significantly reduced while miR-627-5p level was increased."1.51Modulating lncRNA SNHG15/CDK6/miR-627 circuit by palbociclib, overcomes temozolomide resistance and reduces M2-polarization of glioma associated microglia in glioblastoma multiforme. ( Bao, H; Jin, H; Li, C; Li, Z; Liang, P; Wang, W; Xiong, J; Zhang, J; Zheng, H, 2019)
"Glioma is one of the most lethal malignancies and molecular regulators driving gliomagenesis are incompletely understood."1.51DHFR/TYMS are positive regulators of glioma cell growth and modulate chemo-sensitivity to temozolomide. ( Dai, X; He, Q; Shao, Y; Tan, B; Wang, J; Weng, Q; Yang, B; Zhao, M, 2019)
"Glioma is the most common malignant tumor of the central nervous system (CNS)."1.51Blood-Brain Barrier- and Blood-Brain Tumor Barrier-Penetrating Peptide-Derived Targeted Therapeutics for Glioma and Malignant Tumor Brain Metastases. ( Chen, L; Chen, PR; Gao, Y; Li, C; Lin, J; Xu, N; Zeng, D; Zhang, W; Zhu, X, 2019)
"Controlling seizures is essential during GBM treatment because they are often present and closely associated with the quality of life of GBM patients."1.51Effect of anti-epileptic drugs on the survival of patients with glioblastoma multiforme: A retrospective, single-center study. ( Chang, MJ; Min, KL; Ryu, JY, 2019)
"Papaverine is a potential anticancer drug in GBM treatment."1.51Anticancer Non-narcotic Opium Alkaloid Papaverine Suppresses Human Glioblastoma Cell Growth. ( Akasaki, Y; Ichimura, K; Inada, M; Sato, A; Shindo, M; Tanuma, SI; Yamamoto, Y, 2019)
"Euphol is a tetracyclic triterpene alcohol, and it is the main constituent of the sap of the medicinal plant Euphorbia tirucalli."1.51Euphol, a tetracyclic triterpene, from Euphorbia tirucalli induces autophagy and sensitizes temozolomide cytotoxicity on glioblastoma cells. ( Carloni, AC; Costa, AM; Evangelista, AF; Jones, C; Lima, JP; Martinho, O; Miranda-Gonçalves, V; Pianowski, LF; Reis, RM; Rosa, MN; Silva, VAO; Tansini, A, 2019)
"Diffuse low-grade gliomas (DLGG) are brain tumors of young adults."1.51Data-Driven Predictive Models of Diffuse Low-Grade Gliomas Under Chemotherapy. ( Abdallah, MB; Blonski, M; Darlix, A; de Champfleur, NM; Duffau, H; Gaudeau, Y; Moureaux, JM; Taillandier, L; Wantz-Mezieres, S, 2019)
"Glioblastoma is the worst and most common primary brain tumor."1.51CD73 Downregulation Decreases In Vitro and In Vivo Glioblastoma Growth. ( Azambuja, JH; Battastini, AMO; Beckenkamp, LR; Braganhol, E; de Oliveira, FH; Fernandes, MC; Figueiró, F; Gelsleichter, NE; Iser, IC; Scholl, JN; Sévigny, J; Spanevello, RM; Stefani, MA; Teixeira, HF; Wink, MR, 2019)
"Glioblastoma is the most common and lethal adult brain tumor."1.51SOX3 can promote the malignant behavior of glioblastoma cells. ( Aldaz, P; Anastasov, N; Atkinson, MJ; Drakulic, D; Garcia, I; Garros-Regulez, L; Marjanovic Vicentic, J; Matheu, A; Nikolic, I; Puskas, N; Raicevic, S; Sampron, N; Stevanovic, M; Tasic, G; Vukovic, V, 2019)
"Malignant gliomas are aggressive primary neoplasms that originate in the glial cells of the brain or the spine with notable resistance to standard treatment options."1.51Resveratrol restores sensitivity of glioma cells to temozolamide through inhibiting the activation of Wnt signaling pathway. ( Bu, XY; Gao, YS; Han, SY; Hu, S; Qu, MQ; Wang, BQ; Wang, JY; Yan, ZY; Yang, B; Yang, HC, 2019)
"Pathology was anaplastic oligodendroglioma (AOD) and anaplastic astrocytoma IDH-mutated (AAmut) in 32 and 21 patients respectively."1.51Tumour volume reduction following PET guided intensity modulated radiation therapy and temozolomide in IDH mutated anaplastic glioma. ( Back, M; Bailey, D; Brazier, D; Guo, L; Hsiao, E; Jayamanne, D; Wheeler, H, 2019)
"Malignant glioma is a lethal brain tumor with a low survival rate and poor prognosis."1.51Carnosic acid potentiates the anticancer effect of temozolomide by inducing apoptosis and autophagy in glioma. ( Lan, Q; Mao, J; Shao, N; Wang, R; Xue, L; Zhi, F, 2019)
"our data underline re-RT as a safe and feasible treatment with limited rate of toxicity, and a combined ones as a better option for selected patients."1.51Re-irradiation for recurrent glioma: outcome evaluation, toxicity and prognostic factors assessment. A multicenter study of the Radiation Oncology Italian Association (AIRO). ( Alongi, F; Amelio, D; Borzillo, V; Ciammella, P; Clerici, E; di Monale, MB; Draghini, L; Fariselli, L; Ferrarese, F; Fiorentino, A; Galaverni, M; Krengli, M; Livi, L; Magrini, S; Maranzano, E; Masini, L; Minniti, G; Muto, P; Navarria, P; Pasqualetti, F; Pinzi, V; Scartoni, D; Scoccianti, S; Scorsetti, M; Tomatis, S, 2019)
"Human glioblastoma is a malignant and aggressive primary human brain solid tumor characterized by severe hypoxia."1.51The HIF‑1α/miR‑224‑3p/ATG5 axis affects cell mobility and chemosensitivity by regulating hypoxia‑induced protective autophagy in glioblastoma and astrocytoma. ( He, X; Huang, S; Li, F; Qi, P; Zhang, T, 2019)
"Glioma is the most common brain malignancy."1.51Local delivery of temozolomide via a biologically inert carrier (Temodex) prolongs survival in glioma patients, irrespectively of the methylation status of MGMT. ( Fedulov, A; Karlsson, I; Lokot, I; Pejler, G; Veevnik, D; Yurkshtovich, N; Yurkshtovich, T, 2019)
" Delivery outcomes are evaluated by the bioavailability of free temozolomide across time."1.51Delivery of liposome encapsulated temozolomide to brain tumour: Understanding the drug transport for optimisation. ( Zhan, W, 2019)
"Isofuranodiene (IFD) is a bioactive sesquiterpene occurring in the essential oils obtained from Alexanders (Smyrnium olusatrum L."1.51Isofuranodiene synergizes with temozolomide in inducing glioma cells death. ( Amantini, C; Brunetti, A; Iannarelli, R; Maggi, F; Marinelli, O; Morelli, MB; Nabissi, M; Russotti, D; Santoni, G, 2019)
" The procedure was well-tolerated, with no adverse clinical or radiologic events related to the procedure."1.51Blood-Brain Barrier Opening in Primary Brain Tumors with Non-invasive MR-Guided Focused Ultrasound: A Clinical Safety and Feasibility Study. ( Alkins, R; Bethune, A; Heyn, C; Huang, Y; Hynynen, K; Ironside, S; Lipsman, N; Mainprize, T; Meng, Y; Perry, J; Sahgal, A; Trudeau, M, 2019)
"Glioma is a primary intracranial malignant tumor with poor prognosis."1.51Development of transferrin-modified poly(lactic-co-glycolic acid) nanoparticles for glioma therapy. ( Liu, G; Mao, J; Meng, X; Yang, Y; Zhao, C, 2019)
"The aim of the present study was to treat glioblastoma cells with a selective HDAC6 inhibitor, tubastatin A, to determine if the malignant phenotype may be reverted."1.51Tubastatin A, an inhibitor of HDAC6, enhances temozolomide‑induced apoptosis and reverses the malignant phenotype of glioblastoma cells. ( Castresana, JS; Erausquin, E; Idoate, MA; Meléndez, B; Rey, JA; Urdiciain, A, 2019)
" Combinatorial therapy of diosgenin and TMZ significantly reduced the dosage regimen of TMZ and also showed affectivity in hitherto TMZ resistant GBM cells."1.51Targeting NFE2L2, a transcription factor upstream of MMP-2: A potential therapeutic strategy for temozolomide resistant glioblastoma. ( Banerjee, I; Banik, P; Bharti, R; Biswas, A; Das, S; Ghosh, SK; Kumar, U; Mandal, M; Nayak, S; Rajesh, Y, 2019)
"Glioma is a common brain tumor with a high mortality rate."1.51Mild thermotherapy and hyperbaric oxygen enhance sensitivity of TMZ/PSi nanoparticles via decreasing the stemness in glioma. ( Bai, X; Hu, M; Jia, L; Li, Y; Tan, X; Wang, Q; Yang, X; Zeng, X; Zhang, Z; Zhu, Y, 2019)
"Temozolomide treatment inhibited p50 recruitment to its cognate element as a function of Ser329 phosphorylation while concomitantly increasing p53 recruitment."1.51Temozolomide Treatment Induces lncRNA MALAT1 in an NF-κB and p53 Codependent Manner in Glioblastoma. ( Bernal, GM; Cahill, KE; Crawley, CD; Khodarev, NN; Larsen, G; Mansour, NM; Nunez, L; Raleigh, DR; Spretz, R; Szymura, SJ; Uppal, A; Voce, DJ; Weichselbaum, RR; Wu, L; Yamini, B; Zhang, W, 2019)
"Temozolomide (TMZ) is an important agent against GBM."1.51Inhibition of cyclin E1 overcomes temozolomide resistance in glioblastoma by Mcl-1 degradation. ( Chen, Z; Liang, H; Sun, L, 2019)
"Temozolomide (TMZ) has been the first-line chemotherapeutic agent used, although to achieve a satisfactory clinical effect."1.51Synergistic Suppression of Glioblastoma Cell Growth by Combined Application of Temozolomide and Dopamine D2 Receptor Antagonists. ( Gao, L; Huang, X; Jiang, X; Li, J; Liu, X; Liu, Z; Zeng, T, 2019)
"The therapeutic treatment of glioblastoma multiforme (GBM) remains a major challenge."1.51Angiopep-2 Modified Cationic Lipid-Poly-Lactic-Co-Glycolic Acid Delivery Temozolomide and DNA Repair Inhibitor Dbait to Achieve Synergetic Chemo-Radiotherapy Against Glioma. ( Hua, L; Li, S; Liang, J; Liu, H; Xu, Q; Ye, C; Yu, R; Zhao, L, 2019)
"Glioblastoma multiforme is an astrocyte-derived tumour representing the most aggressive primary brain malignancy."1.51Temozolomide-induced aplastic anaemia and incidental low-grade B-cell non-Hodgkin lymphoma in a geriatric patient with glioblastoma multiforme. ( Aleixo, GF; Batalini, F; Drews, R; Kaufmann, MR, 2019)
"Glioblastoma is the most common primary brain tumor in adults."1.51ID1 Is Critical for Tumorigenesis and Regulates Chemoresistance in Glioblastoma. ( Al-Omaishi, S; Celebre, A; Chan, J; Das, S; Dirks, PB; Ghannad-Zadeh, K; Guan, J; Isaev, K; Kaskun, O; Moran, MF; Morrissy, AS; Munoz, DG; Reimand, J; Sachdeva, R; Smiljanic, S; Taylor, MD; Tong, J; Wilson, TM; Wu, M, 2019)
"Glioma is the most common type of primary brain tumor and has an undesirable prognosis."1.48β-asarone inhibited cell growth and promoted autophagy via P53/Bcl-2/Bclin-1 and P53/AMPK/mTOR pathways in Human Glioma U251 cells. ( Fang, Y; Luo, L; Ning, B; Wang, N; Zhang, Q, 2018)
" Proliferation, cell cycle, and apoptotic assays were performed with ML00253764, whereas the synergism of the simultaneous combination with temozolomide was evaluated by the combination index method."1.48Melanocortin Receptor-4 and Glioblastoma Cells: Effects of the Selective Antagonist ML00253764 Alone and in Combination with Temozolomide In Vitro and In Vivo. ( Bocci, G; Di Desidero, T; Giuliani, D; Guarini, S; Orlandi, P; Ottani, A; Pacini, S; Pardini, C; Pasqualetti, F; Vaglini, F, 2018)
"Radiochemotherapy involving cisplatinum-based polychemotherapy is more toxic than radiotherapy in combination with temozolomide."1.48Concurrent radiotherapy with temozolomide vs. concurrent radiotherapy with a cisplatinum-based polychemotherapy regimen : Acute toxicity in pediatric high-grade glioma patients. ( Bison, B; Bojko, S; Gielen, GH; Hoffmann, M; Kortmann, RD; Kramm, CM; Pietsch, T; Seidel, C; von Bueren, AO; Warmuth-Metz, M, 2018)
"OBJECTIVE Glioblastoma is the most common primary central nervous system tumor in adults."1.48Enhancement of invadopodia activity in glioma cells by sublethal doses of irradiation and temozolomide. ( Kaye, AH; Luwor, RB; Mao, L; Morokoff, AP; Paradiso, L; Stylli, SS; Whitehead, CA, 2018)
"Temozolomide (TMZ) has been considered to be one of the most effective chemotherapeutic agents to prolong the survival of patients with glioblastoma."1.48Differential Characterization of Temozolomide-Resistant Human Glioma Cells. ( Chen, CC; Huang, BR; Lai, SW; Lin, C; Lin, HY; Liu, YS; Lu, DY; Tsai, CF, 2018)
"Glioblastoma (GBM) is the most malignant primary brain tumor and contains tumorigenic cancer stem cells (CSCs), which support the progression of tumor growth."1.48Biomimetic brain tumor niche regulates glioblastoma cells towards a cancer stem cell phenotype. ( Chen, PY; Lee, IC; Liu, YC, 2018)
"Oligodendrogliomas are therapy-responsive tumors, which have better prognosis compared to their astrocytic counterparts."1.48Chemotherapy of Oligodendrogliomas. ( Drappatz, J; Lieberman, F, 2018)
"Central nervous system primitive neuroectodermal tumors (CNS PNETs) mostly occur in children and present as cerebellar medulloblastoma."1.48A primitive neuroectodermal tumor in an adult: Case report of a unique location and MRI characteristics. ( Chen, Z; Dong, Y; He, X; Tong, D, 2018)
"Glioma is the most common intracranial malignant tumors, accounting for about 40% of intracranial tumors."1.48MiR-634 sensitizes glioma cells to temozolomide by targeting CYR61 through Raf-ERK signaling pathway. ( Jiang, Y; Tan, Z; Zhao, J, 2018)
"Glioblastoma is the most frequent and aggressive form of high-grade malignant glioma."1.48XRCC3 contributes to temozolomide resistance of glioblastoma cells by promoting DNA double-strand break repair. ( Frohnapfel, L; Kaina, B; Quiros, S; Ringel, F; Roos, WP, 2018)
"Glioblastoma multiforme is the most lethal type of brain tumor and the established therapy only extends patients survival to approximately one year."1.48Receptor-mediated PLGA nanoparticles for glioblastoma multiforme treatment. ( Coelho, MAN; Gosselet, F; Lima, J; Loureiro, JA; Pereira, MC; Ramalho, MJ; Sevin, E, 2018)
" In addition, TMZ could increase the levels of miR-505 and combination with pri-miR-505 and TMZ promoted the suppressive role mediated by miR-505 in GBM cells."1.48Combination with TMZ and miR-505 inhibits the development of glioblastoma by regulating the WNT7B/Wnt/β-catenin signaling pathway. ( Fu, C; Liu, X; Yang, X; Zhang, C, 2018)
"We performed a retrospective analysis to compare the efficacy of whole brain radiotherapy (WBRT) combined with temozolomide (TMZ) versus WBRT alone as first-line treatment for brain metastases (BM)."1.48Effectiveness of temozolomide combined with whole brain radiotherapy for non-small cell lung cancer brain metastases. ( Fu, L; Guo, D; Jing, W; Kong, L; Yu, J; Zhu, Y, 2018)
"Peripheral primitive neuroectodermal tumors of the lumbar paraspinal region with diffuse and strong glial differentiation have never been reported before."1.48Successful Novel Treatment of a Paraspinal Primitive Neuroectodermal Tumor with Predominantly Glial Differentiation: A 3-Year Follow-Up After Surgery, Intensity-Modulated Radiation Therapy and Oral Temozolomide. ( Botros, J; El Ahmadieh, TY; Gluf, W; Kabangu, JL; Pan, E; Raisanen, JM, 2018)
"Glioblastoma is the most common and aggressive primitive brain tumor in adults."1.48Good tolerability of maintenance temozolomide in glioblastoma patients after severe hematological toxicity during concomitant radiotherapy and temozolomide treatment: report of two cases. ( Bellu, L; Bergo, E; Berti, F; Caccese, M; Dal Pos, S; Della Puppa, A; Denaro, L; Gardiman, MP; Lombardi, G; Pambuku, A; Zagonel, V, 2018)
" Our results demonstrate benefit of ddTMZ after previous treatment with standard TMZ dosing with no apparent increase in treatment-related toxicities."1.48Dose-dense temozolomide for recurrent high-grade gliomas: a single-center retrospective study. ( Garcia, CR; Gruber, L; Kumar, SS; Lightner, DD; Morgan, RM; Slone, SA; Villano, JL, 2018)
"Glioblastoma is the most common malignant brain tumor."1.48Nose-to-brain delivery of temozolomide-loaded PLGA nanoparticles functionalized with anti-EPHA3 for glioblastoma targeting. ( Chu, L; Liu, S; Mu, H; Ni, L; Song, Y; Sun, K; Wang, A; Wu, Z; Yan, X; Zhang, C; Zhao, M, 2018)
"Glioma is the most common and lethal primary brain tumor."1.48Cell Subpopulations Overexpressing p75NTR Have Tumor-initiating Properties in the C6 Glioma Cell Line. ( Chen, MF; Cheng, CY; Wang, TC; Yang, WH, 2018)
"GBM is a deadly brain cancer that doesn't discriminate between sexes and knows no age limit."1.48A Novel Venom-Derived Peptide for Brachytherapy of Glioblastoma: Preclinical Studies in Mice. ( Chen, TC; Markland, FS; Minea, RO; Swenson, S; Thein, TZ; Tuan, CD, 2018)
"Temozolomide (TMZ) is a drug used to treat GBM, while the survival period of GBM patients with positive treatment remains less than 15 months."1.48Study on Therapeutic Action and Mechanism of TMZ Combined with RITA Against Glioblastoma. ( Cao, Z; Li, L; Wu, Q; Xiao, W; Xie, Q; Zhang, B; Zhao, W; Zhu, L, 2018)
"Human glioma is the most common type of primary brain tumor."1.48Downregulation of miR-196b Promotes Glioma Cell Sensitivity to Temozolomide Chemotherapy and Radiotherapy. ( Liu, J; Lv, H; Ma, R; Shao, C; Zhang, G; Zheng, G, 2018)
" ATOR showed similar cytotoxic effect as TMZ to glioma cells, and it may be a safer drug, regarding side effect induction, than chemotherapic agents."1.48Atorvastatin Promotes Cytotoxicity and Reduces Migration and Proliferation of Human A172 Glioma Cells. ( Dal-Cim, T; Lopes, FG; Ludka, FK; Nedel, CB; Oliveira, KA; Tasca, CI, 2018)
"Glioblastoma (GBM) is one of the lethal central nervous system tumors."1.48The Effect of Ascorbic Acid over the Etoposide- and Temozolomide-Mediated Cytotoxicity in Glioblastoma Cell Culture: A Molecular Study. ( Ceylan, S; Gokturk, D; Kelebek, H; Yilmaz, DM, 2018)
"Glioma is the most common primary brain tumor and has an undesirable prognosis due to the blood-brain barrier (BBB) and drug resistance."1.46β-Asarone promotes Temozolomide's entry into glioma cells and decreases the expression of P-glycoprotein and MDR1. ( Fang, Y; Luo, L; Ning, B; Wang, N; Zhang, Q, 2017)
"Glioblastomas (GBM) comprise 17% of all primary brain tumors."1.46Dual treatment with shikonin and temozolomide reduces glioblastoma tumor growth, migration and glial-to-mesenchymal transition. ( Balça-Silva, J; do Carmo, A; Dubois, LG; Echevarria-Lima, J; Ferrer, VP; Lopes, MC; Matias, D; Moura-Neto, V; Pontes, B; Rosário, L; Sarmento-Ribeiro, AB, 2017)
"Glioblastoma is one of the most frequent and aggressive brain tumors."1.46MiR-198 enhances temozolomide sensitivity in glioblastoma by targeting MGMT. ( Jin, X; Liu, N; Nie, E; Shi, Z; Wu, W; You, Y; Yu, T; Zhang, J; Zhou, X, 2017)
"Chlorpromazine is a United States Food and Drug Administration-approved phenothiazine widely used as a psychotropic in clinical practice."1.46Repositioning chlorpromazine for treating chemoresistant glioma through the inhibition of cytochrome c oxidase bearing the COX4-1 regulatory subunit. ( Griguer, CE; Langford, C; Oliva, CR; Suto, MJ; Zhang, W, 2017)
"Neuroendocrine tumors are rare, and little is known about the existence of cancer stem cells in this disease."1.46Establishment of a tumor sphere cell line from a metastatic brain neuroendocrine tumor. ( Asai, A; Ito, T; Iwata, R; Kanemura, Y; Koike, T; Maruyama, M; Nakano, Y; Nomura, S; Nonaka, M; Oe, S; Sugimoto, T; Yamada, H; Yoshimura, K, 2017)
"Guanosine (GUO) is an endogenous nucleoside involved in extracellular signaling that presents neuroprotective effects and also shows the effect of inducing differentiation in cancer cells."1.46Guanosine promotes cytotoxicity via adenosine receptors and induces apoptosis in temozolomide-treated A172 glioma cells. ( Dal-Cim, TA; Lopes, FG; Nedel, CB; Oliveira, KA; Tasca, CI, 2017)
"Temozolomide (TMZ) is an alkylating chemotherapeutic agent widely used in anti-glioma treatment."1.46Genomic profiling of long non-coding RNA and mRNA expression associated with acquired temozolomide resistance in glioblastoma cells. ( Fu, Z; Guo, H; Lian, C; Liu, B; Liu, Y; Xu, N; Yang, Z; Zeng, H, 2017)
"The current treatment of glioblastoma multiforme (GBM) is limited by the restricted arsenal of agents which effectively cross the blood brain barrier (BBB)."1.46The use of TMZ embedded hydrogels for the treatment of orthotopic human glioma xenografts. ( Adhikari, B; Akers, J; Brandel, MG; Carter, BS; Chen, CC; Deming, T; Futalan, D; Li, J, 2017)
"Glioblastoma is a highly lethal brain cancer that frequently recurs in proximity to the original resection cavity."1.46Zika virus has oncolytic activity against glioblastoma stem cells. ( Chai, JN; Chheda, MG; Diamond, MS; Fernandez, E; Gorman, MJ; Hubert, CG; McKenzie, LD; Prager, BC; Rich, JN; Richner, JM; Shan, C; Shi, PY; Tycksen, E; Wang, X; Zhang, R; Zhu, Z, 2017)
"Glioblastoma is the most common and aggressive primary brain tumor and has a high mortality in humans."1.46Identification of WISP1 as a novel oncogene in glioblastoma. ( Jing, D; Shen, L; Yu, H; Zhang, Q; Zhao, Y, 2017)
"Malignant gliomas are a group of aggressive neoplasms among human cancers."1.46Hyperthermia with different temperatures inhibits proliferation and promotes apoptosis through the EGFR/STAT3 pathway in C6 rat glioma cells. ( An, TT; Chen, YD; Dong, TX; Liu, PF; Xu, YT; Yang, XH; Zhang, W; Zhang, Y, 2017)
"Among 350 glioma and ganglioglioma cases, the MGMT promoter tested positive for methylation in 53."1.46Comparative assessment of three methods to analyze MGMT methylation status in a series of 350 gliomas and gangliogliomas. ( Chen, L; Hu, Z; Li, Z; Liu, C; Liu, L; Lu, D; Teng, L; Wang, L; Zhao, L, 2017)
" In vivo, systemic treatment with pacritinib demonstrated blood-brain barrier penetration and led to improved overall median survival in combination with TMZ, in mice orthotopically xenografted with an aggressive recurrent GBM BTIC culture."1.46The JAK2/STAT3 inhibitor pacritinib effectively inhibits patient-derived GBM brain tumor initiating cells in vitro and when used in combination with temozolomide increases survival in an orthotopic xenograft model. ( Aman, A; Cseh, O; Jensen, KV; Luchman, HA; Weiss, S, 2017)
" In vivo, we implanted the cells orthotopically in nude mice and administered CBL0137 in various dosing regimens to assess brain and tumor accumulation of CBL0137, its effect on tumor cell proliferation and apoptosis, and on survival of mice with and without temozolomide (TMZ)."1.46Anticancer drug candidate CBL0137, which inhibits histone chaperone FACT, is efficacious in preclinical orthotopic models of temozolomide-responsive and -resistant glioblastoma. ( Barone, TA; Burkhart, CA; Gudkov, AV; Gurova, KV; Haderski, G; Plunkett, RJ; Purmal, AA; Safina, A, 2017)
"Temozolomide is a commonly used chemotherapy drug and frequently causes lymphocytopenia."1.46Cutaneous invasive aspergillosis in a patient with glioblastoma receiving long-term temozolomide and corticosteroid therapy. ( Hatakeyama, S; Ikeda, T; Morisawa, Y; Norizuki, M; Okabe, T; Onishi, T; Sasahara, T; Suzuki, J; Toshima, M; Yokota, H, 2017)
"Temozolomide (TMZ) is a novel cytotoxic agent used as first-line chemotherapy for GBM, however, some individual cells can't be isolated for surgical resection and show treatment-resistance, thus inducing poor prognosis."1.46MALAT1 is a prognostic factor in glioblastoma multiforme and induces chemoresistance to temozolomide through suppressing miR-203 and promoting thymidylate synthase expression. ( Chen, C; Chen, W; Ge, XS; He, J; Kong, KK; Li, FC; Li, H; Li, JL; Li, P; Wang, F; Xu, XK, 2017)
"6 μg/day) with negligible leakage into the peripheral blood (<100 ng) rendering ~1000 fold differential drug dosage in tumor versus peripheral blood."1.46Theranostic 3-Dimensional nano brain-implant for prolonged and localized treatment of recurrent glioma. ( Ashokan, A; Gowd, GS; Junnuthula, VR; Koyakutty, M; Nair, SV; Panikar, D; Peethambaran, R; Ramachandran, R; Thomas, A; Thomas, J; Unni, AK, 2017)
"A 43-year-old man with an anaplastic astrocytoma received radiation therapy synchronized with ranimustine and adjuvant TMZ chemotherapy for 15 cycles."1.46A Case of Therapy-Related Acute Myeloid Leukemia Associated with Adjuvant Temozolomide Chemotherapy for Anaplastic Astrocytoma. ( Kosugi, K; Saito, K; Takahashi, W; Tokuda, Y; Tomita, H, 2017)
"Orthotopic xenograft model of human brain cancer cells is a good preclinical model for evaluation of antitumor compounds."1.43[Establishment of a glioma orthotopic xenograft model based on imaging technology]. ( Chen, XG; Ji, M; Lai, FF; Lü, YH; Wang, LY, 2016)
"Glioblastoma is the deadliest brain tumor in humans."1.43Anti-tumor activities of luteolin and silibinin in glioblastoma cells: overexpression of miR-7-1-3p augmented luteolin and silibinin to inhibit autophagy and induce apoptosis in glioblastoma in vivo. ( Chakrabarti, M; Ray, SK, 2016)
"Primary brain tumors are hallmarked for their destructive activity on the microenvironment and vasculature."1.43A versatile ex vivo technique for assaying tumor angiogenesis and microglia in the brain. ( Buchfelder, M; Eyüpoglu, IY; Fan, Z; Ghoochani, A; Hock, S; Savaskan, NE; Sehm, T; Yakubov, E, 2016)
"The study included 26 patients with anaplastic astrocytoma and 37 patients with glioblastoma; all patients were aged ≤18 years."1.43High-grade glioma in children and adolescents: a single-center experience. ( Akalan, N; Akyuz, C; Cengiz, M; Eren, G; Gurkaynak, M; Ozyigit, G; Varan, A; Yazici, G; Yüce, D; Zorlu, F, 2016)
"BBBD temozolomide was toxic in the efficacy study, but there was no evidence of symptomatic neurotoxicity in rats given IA temozolomide."1.43Intra-arterial administration improves temozolomide delivery and efficacy in a model of intracerebral metastasis, but has unexpected brain toxicity. ( Muldoon, LL; Netto, JP; Neuwelt, EA; Pagel, MA, 2016)
"Valproic acid (VPA) is an anti-epileptic drug with properties of a histone deacetylase inhibitor (HDACi)."1.43Valproic acid, compared to other antiepileptic drugs, is associated with improved overall and progression-free survival in glioblastoma but worse outcome in grade II/III gliomas treated with temozolomide. ( Dietrich, J; Le, A; McDonnell, E; Nahed, BV; Redjal, N; Reinshagen, C; Walcott, BP, 2016)
"There is no standard treatment for glioblastoma with elements of PNET (GBM-PNET)."1.43Craniospinal irradiation with concomitant and adjuvant temozolomide--a feasibility assessment of toxicity in patients with glioblastoma with a PNET component. ( Fersht, N; Mandeville, HC; Mycroft, J; O'Leary, B; Saran, F; Solda, F; Vaidya, S; Zacharoulis, S, 2016)
"Glioblastoma is the most common and deadly primary brain tumor in adults."1.43Additive antiangiogenesis effect of ginsenoside Rg3 with low-dose metronomic temozolomide on rat glioma cells both in vivo and in vitro. ( Feng, F; Ling, Z; Sun, C; Wang, L; Wang, S; Wu, B; Xia, L; Yu, Y, 2016)
"Glioblastoma multiforme is a devastating disease with no curative options due to the difficulty in achieving sufficient quantities of effective chemotherapies into the tumor past the blood-brain barrier."1.43Delivery of a drug cache to glioma cells overexpressing platelet-derived growth factor receptor using lipid nanocarriers. ( Bredlau, AL; Broome, AM; Dixit, S; McKinnon, E; Miller, K; Moore, A, 2016)
"Malignant gliomas are among the most frequent and aggressive cerebral tumors, characterized by high proliferative and invasive indexes."1.43KCa3.1 channel inhibition sensitizes malignant gliomas to temozolomide treatment. ( Catalano, M; Chece, G; D'Alessandro, G; Di Angelantonio, S; Esposito, V; Grimaldi, A; Limatola, C; Mainiero, F; Porzia, A; Ragozzino, D; Salvati, M; Santoro, A; Wulff, H, 2016)
"Glioblastomas (GBM), deadly brain tumors, have greater incidence in males than females."1.43Selective Estrogen Receptor β Agonist LY500307 as a Novel Therapeutic Agent for Glioblastoma. ( Brenner, A; Cavazos, D; Garcia, L; Garcia, M; Gruslova, A; Gustafsson, JA; Li, X; Liu, J; Sareddy, GR; Strom, AM; Tekmal, RR; Vadlamudi, RK; Viswanadhapalli, S, 2016)
"Fotemustine (FTM) is a third-generation nitrosourea showing efficacy in gliomas and it has been used with different schedules in adult patients."1.43Clinical outcome of an alternative fotemustine schedule in elderly patients with recurrent glioblastoma: a mono-institutional retrospective study. ( Bellu, L; D'Avella, D; Della Puppa, A; Farina, M; Fiduccia, P; Lombardi, G; Pambuku, A; Zagonel, V, 2016)
"The analysis included all patients treated for gliosarcoma between 1998 and 2014 in seven French academic centres."1.43Prognostic and therapeutic factors of gliosarcoma from a multi-institutional series. ( Antoni, D; Berger, A; Biau, J; Castelli, J; Crehange, G; de Crevoisier, R; Feuvret, L; Gutierrez, FL; Haoming, QC; Jouglar, E; Le Reste, PJ; Loussouarn, D; Morandi, X; Noel, G; Nouhaud, E; Thillays, F; Truc, G; Vauleon, E, 2016)
"Dysembryoplastic neuroepithelial tumors (DNETs) are low-grade neuroglial tumors that are traditionally considered to be benign hamartoma-like mass lesions."1.43Radiologic response to radiation therapy concurrent with temozolomide for progressive simple dysembryoplastic neuroepithelial tumor. ( Fenstermaker, RA; Mechtler, LL; Morr, S; Prasad, D; Qiu, J, 2016)
" We show that GSI in combination with RT and TMZ attenuates proliferation, decreases 3D spheroid growth and results into a marked reduction in clonogenic survival in primary and established glioma cell lines."1.43NOTCH blockade combined with radiation therapy and temozolomide prolongs survival of orthotopic glioblastoma. ( Barbeau, LM; Chalmers, AJ; Eekers, DB; Granton, PV; Groot, AJ; Habets, R; Iglesias, VS; King, H; Prickaerts, J; Short, SC; Theys, J; van Hoof, SJ; Verhaegen, F; Vooijs, M; Yahyanejad, S, 2016)
" We investigated the pharmacologic characteristics of OTX015 as a single agent and combined with targeted therapy or conventional chemotherapies in glioblastoma cell lines."1.43OTX015 (MK-8628), a novel BET inhibitor, displays in vitro and in vivo antitumor effects alone and in combination with conventional therapies in glioblastoma models. ( Astorgues-Xerri, L; Bekradda, M; Berenguer-Daizé, C; Cayol, M; Cvitkovic, E; Lokiec, F; MacKenzie, S; Noel, K; Odore, E; Ouafik, L; Rezai, K; Riveiro, ME, 2016)
" As a comparison group 33 patients with bevacizumab for at least 6 months continuously dosed at 10 mg/kg every 2 weeks were selected."1.43Impact of tapering and discontinuation of bevacizumab in patients with progressive glioblastoma. ( Hertenstein, A; Hielscher, T; Menn, O; Platten, M; Wick, A; Wick, W; Wiestler, B; Winkler, F, 2016)
"Pituitary adenomas are the commonest intracranial tumor, but metastases are rare (0."1.43Widely metastatic atypical pituitary adenoma with mTOR pathway STK11(F298L) mutation treated with everolimus therapy. ( Arnal, AV; Donovan, LE; Odia, Y; Wang, SH, 2016)
"Glioblastoma multiforme is the most aggressive malignant primary brain tumor in adults."1.43Increased Expression of System xc- in Glioblastoma Confers an Altered Metabolic State and Temozolomide Resistance. ( Aboody, KS; Cassady, K; Cherryholmes, GA; Marinov, GK; Polewski, MD; Reveron-Thornton, RF, 2016)
"Gliomas are the most common primary intracranial malignant tumors in adults."1.43Analysis of expression and prognostic significance of vimentin and the response to temozolomide in glioma patients. ( Cai, J; Han, B; Jiang, C; Lin, L; Meng, X; Ming, J; Sun, B; Wang, G, 2016)
"Glioma is still difficult to treat because of its high malignancy, high recurrence rate, and high resistance to anticancer drugs."1.433D bioprinted glioma stem cells for brain tumor model and applications of drug susceptibility. ( Dai, X; Lan, Q; Ma, C; Xu, T, 2016)
"Temozolomide (TMZ) is an alkylating agent used for the treatment of aggressive forms of brain tumor based on its antitumor actions."1.43Temozolomide inhibits cellular growth and motility via targeting ERK signaling in glioma C6 cells. ( Gao, S; Liang, J; Wang, W; Wang, Y, 2016)
"Patients with grade IV astrocytoma or glioblastoma multiforme (GBM) have a median survival of <12 months, increased to 14."1.43Regression of a glioblastoma multiforme: spontaneous versus a potential antineoplastic effect of dexamethasone and levetiracetam. ( Ajit, NE; Burton, GV; El-Osta, H; Peddi, P, 2016)
"Diffuse low-grade gliomas are rare primitive cerebral tumours of adults."1.43Predictive models for diffuse low-grade glioma patients under chemotherapy. ( Ben Abdallah, M; Blonski, M; Gaudeau, Y; Moureaux, JM; Taillandier, L; Wantz-Mezieres, S, 2016)
"Seizures are a common symptom in patients with low-grade glioma (LGG), negatively influencing quality of life, if uncontrolled."1.42Seizure reduction in a low-grade glioma: more than a beneficial side effect of temozolomide. ( Dirven, L; Heimans, JJ; Koekkoek, JA; Postma, TJ; Reijneveld, JC; Taphoorn, MJ; Vos, MJ, 2015)
"Glioblastoma is a highly aggressive, common brain tumor with poor prognosis."1.42RIST: a potent new combination therapy for glioblastoma. ( Corbacioglu, S; Debatin, KM; Engelke, J; Fulda, S; Halatsch, ME; Karpel-Massler, G; Nonnenmacher, L; Simmet, T; Westhoff, MA, 2015)
"Malignant glioma is a common and lethal primary brain tumor in adults."1.42VAMP8 facilitates cellular proliferation and temozolomide resistance in human glioma cells. ( Chen, H; Chen, J; Chen, Y; Fan, J; Hu, L; Huai, C; Lu, D; Meng, D; Qin, R; Song, X; Sun, R; Wang, D; Wang, H; Wang, J; Wang, S; Xu, T; Yang, J; Yang, S; Yun, D; Zhang, X; Zhao, Y, 2015)
"These results suggest that Liq treatment enhances glioma cell susceptibility to TMZ by inhibiting the PI3K/AKT/mTOR pathway."1.42Estrogen receptor β agonist enhances temozolomide sensitivity of glioma cells by inhibiting PI3K/AKT/mTOR pathway. ( Chen, J; Jing, L; Li, L; Li, S; Ling, Q; Liu, X; Wang, H; Wang, L; Xia, M; Yang, S, 2015)
"Glioblastoma is the most aggressive primary brain tumor, and is associated with a very poor prognosis."1.42Prediction of clinical outcome in glioblastoma using a biologically relevant nine-microRNA signature. ( Alder, JE; Boissinot, M; Droop, A; Hayes, J; Hughes, TA; Lawler, SE; Shaw, L; Short, SC; Thygesen, H; Tumilson, C; Westhead, D, 2015)
"Glioblastoma is a devastating primary brain tumor resistant to conventional therapies."1.42Autophagy inhibition improves the efficacy of curcumin/temozolomide combination therapy in glioblastomas. ( Battastini, AM; Bishop, AJR; Braganhol, E; Bristot, IJ; Figueiró, F; Forcelini, CM; Gelain, DP; Klafke, K; Moreira, JCF; Morrone, M; Paludo, FJ; Terra, SR; Zanotto-Filho, A, 2015)
"Glioblastoma is the most frequent primary malignant brain tumor in adults."1.42Combined anti-Galectin-1 and anti-EGFR siRNA-loaded chitosan-lipid nanocapsules decrease temozolomide resistance in glioblastoma: in vivo evaluation. ( Benoit, JP; Danhier, F; Lagarce, F; Lemaire, L; Messaoudi, K, 2015)
" Primary GBM cells were treated with VPA as a monotherapy and in combination with temozolomide and irradiation."1.42The effect of valproic acid in combination with irradiation and temozolomide on primary human glioblastoma cells. ( Cosgrove, L; Day, B; Fay, M; Head, R; Hosein, AN; Lim, YC; Martin, JH; Rose, S; Sminia, P; Stringer, B, 2015)
"Glioblastoma is the most malignant brain tumor, exhibiting remarkable resistance to treatment."1.42A transcriptomic signature mediated by HOXA9 promotes human glioblastoma initiation, aggressiveness and resistance to temozolomide. ( Correia, S; Costa, BM; Costa, S; Gonçalves, CS; Gonçalves, T; Lopes, JM; Oliveira, AI; Pinto, AA; Pinto, L; Pojo, M; Reis, RM; Rocha, M; Rodrigues, AJ; Sousa, N; Xavier-Magalhães, A, 2015)
"Irinotecan has shown some efficacy in recurrent malignant gliomas."1.42Preclinical impact of bevacizumab on brain and tumor distribution of irinotecan and temozolomide. ( Beccaria, K; Carpentier, A; Farinotti, R; Fernandez, C; Goldwirt, L; Idbaih, A; Labussiere, M; Levasseur, C; Milane, A; Schmitt, C, 2015)
"Temozolomide treatment significantly induced mRNA expression of nearly all investigated EMT markers in T98G glioma cells."1.42Epithelial-to-mesenchymal transition in paired human primary and recurrent glioblastomas. ( Hattermann, K; Held-Feindt, J; Kubelt, C; Mehdorn, HM; Sebens, S, 2015)
"Thromboembolic events, seizures, neurologic symptoms and adverse effects from corticosteroids and chemotherapies are frequent clinical complications seen in Glioblastoma (GB) patients."1.42Risk factors for glioblastoma therapy associated complications. ( Brenke, C; Capper, D; Ening, G; Osterheld, F; Schmieder, K, 2015)
"Glioblastoma is the most frequent primary malignant brain tumor in adults."1.42Temozolomide-loaded photopolymerizable PEG-DMA-based hydrogel for the treatment of glioblastoma. ( Danhier, F; des Rieux, A; Fourniols, T; Leprince, JG; Préat, V; Randolph, LD; Staub, A; Vanvarenberg, K, 2015)
"Evidence suggests hyperglycemia is associated with worse outcomes in glioblastoma (GB)."1.42Impact of glycemia on survival of glioblastoma patients treated with radiation and temozolomide. ( Chung, C; Kiehl, TR; Laperriere, N; Lovblom, LE; Mason, W; McNamara, MG; Ménard, C; Millar, BA; Perkins, BA; Tieu, MT, 2015)
"Patients diagnosed with primary brain tumors were treated with PDT."1.42Photodynamic therapy in the treatment of brain tumours. A feasibility study. ( Azinovic, I; Brugarolas, A; Cañón, R; Cases, FG; Rebollo, J; Sapena, NS; Sureda, M; Vanaclocha, V, 2015)
" Abemaciclib antitumor activity was assessed in subcutaneous and orthotopic glioma models alone and in combination with standard of care temozolomide (TMZ)."1.42Brain Exposure of Two Selective Dual CDK4 and CDK6 Inhibitors and the Antitumor Activity of CDK4 and CDK6 Inhibition in Combination with Temozolomide in an Intracranial Glioblastoma Xenograft. ( Ajamie, RT; De Dios, A; Gelbert, LM; Kulanthaivel, P; Raub, TJ; Sanchez-Martinez, C; Sawada, GA; Shannon, HE; Staton, BA; Wishart, GN, 2015)
"Glioblastoma multiforme is the most common malignant brain tumor."1.42An image guided small animal radiation therapy platform (SmART) to monitor glioblastoma progression and therapy response. ( Barbeau, LM; Granton, PV; Paesmans, K; Theys, J; van Hoof, SJ; Verhaegen, F; Vooijs, M; Yahyanejad, S, 2015)
"Temozolomide (TMZ) is an oral alkylating chemotherapeutic agent that prolongs the survival of patients with glioblastoma (GBM)."1.42A New Epigenetic Mechanism of Temozolomide Action in Glioma Cells. ( Barciszewska, AM; Gurda, D; Głodowicz, P; Naskręt-Barciszewska, MZ; Nowak, S, 2015)
"Glioma is one of the most common primary tumors of the central nervous system in adults."1.42Interferon-α/β enhances temozolomide activity against MGMT-positive glioma stem-like cells. ( Chen, FR; Chen, YS; Chen, ZP; Guo, CC; Panasci, L; Qiu, ZK; Sai, K; Shen, D; Wang, J; Yang, QY, 2015)
"Gliomas are the most common primary brain tumors."1.42Inhibition of DNA-repair genes Ercc1 and Mgmt enhances temozolomide efficacy in gliomas treatment: a pre-clinical study. ( Berger, FR; Boccard, SG; Geraci, S; Marand, SV; Pelletier, LA; Pycroft, L, 2015)
" This preclinical study sought to test the efficacy of the food additive Triacetin (glyceryl triacetate, GTA) as a novel therapy to increase acetate bioavailability in glioma cells."1.40Triacetin-based acetate supplementation as a chemotherapeutic adjuvant therapy in glioma. ( Davies, MT; Driscoll, HE; Jaworski, DM; Lawler, SE; Long, PM; Penar, PL; Pendlebury, WW; Spees, JL; Teasdale, BA; Tsen, AR; Viapiano, MS, 2014)
" We report five patients who received long-term treatment with TMZ chemotherapy at normal dosing levels."1.40Long-term treatment with temozolomide in malignant glioma. ( Defrates, SR; Lightner, DD; Mannas, JP; Pittman, T; Villano, JL, 2014)
"Our case exhibited atypical central neurocytoma with an initially elevated MIB-1 labeling index (25-30 %)."1.40Clinical course of central neurocytoma with malignant transformation-an indication for craniospinal irradiation. ( Barzo, P; Cserhati, A; Fodor, E; Hideghety, K; Mozes, P; Szanto, E; Tiszlavicz, L, 2014)
"However, TMZ-related acute lymphoblastic leukemia is rare."1.40Temozolomide-related acute lymphoblastic leukemia with translocation (4;11)(q21;q23) in a glioblastoma patient. ( Chang, PY; Chou, KN; Lin, YC; Liu, MY, 2014)
" More generally, these results suggest that traditional therapy in combination with local, as opposed to systemic, delivery of angiogenesis inhibitors may be able to increase median survival for patients with glioblastoma."1.40Local delivery of angiogenesis-inhibitor minocycline combined with radiotherapy and oral temozolomide chemotherapy in 9L glioma. ( Bow, H; Brem, H; Hwang, LS; Murray, L; Salditch, Q; Schildhaus, N; Tyler, B; Weingart, J; Xing, J; Ye, X; Zhang, Y, 2014)
"One patient with anaplastic ganglioglioma experienced confirmed partial tumor response and significant clinical improvement and she is alive 20 months after start of treatment."1.40Vemurafenib in pediatric patients with BRAFV600E mutated high-grade gliomas. ( Bautista, F; Dufour, C; Geoerger, B; Grill, J; Lacroix, L; Minard-Colin, V; Paci, A; Valteau-Couanet, D; Varlet, P, 2014)
"Glioblastoma is the most common malignant primary brain tumor."1.40EFEMP1 induces γ-secretase/Notch-mediated temozolomide resistance in glioblastoma. ( Boots-Sprenger, SH; Hiddingh, L; Hulleman, E; Jeuken, J; Kaspers, GJ; Noske, DP; Tannous, BA; Teng, J; Tops, B; Vandertop, WP; Wesseling, P; Wurdinger, T, 2014)
"In a cohort of HER2+ breast cancer brain metastases, we identified a gene expression signature that anti-correlates with overexpression of BRCA1."1.40A BRCA1 deficient-like signature is enriched in breast cancer brain metastases and predicts DNA damage-induced poly (ADP-ribose) polymerase inhibitor sensitivity. ( Akbari, MR; Aldape, KD; Denton-Schneider, BR; Hicks, D; Lee, J; McMullin, RP; Moulis, S; Narod, SA; Ramaswamy, S; Sgroi, DC; Singavarapu, R; Steeg, PS; Wittner, BS; Yang, C, 2014)
"Most patients with brain metastases have active extracranial disease, which limits survival unless effective systemic therapy can be administered."1.40Impact of systemic treatment on survival after whole brain radiotherapy in patients with brain metastases. ( Aandahl, G; Dalhaug, A; Haukland, E; Marienhagen, K; Nieder, C; Pawinski, A, 2014)
"optimal treatment of glioblastoma (gBM) in the elderly remains unclear."1.40Glioblastoma treatment in the elderly in the temozolomide therapy era. ( Al-Zahrani, A; Coate, L; Laperriere, N; Lwin, Z; Macfadden, D; Mason, WP; Massey, C; McNamara, MG; Menard, C; Millar, BA; Sahgal, A, 2014)
"Temozolomide (TMZ) is an alkylating agent used for the treatment of glioblastoma multiforme (GBM), the main form of human brain tumours in adults."1.40Bak and Mcl-1 are essential for Temozolomide induced cell death in human glioma. ( Gratas, C; Oliver, L; Rabé, M; Séry, Q; Vallette, FM, 2014)
"Glioma is one of the most aggressive and lethal human brain tumors."1.40MiR-124 governs glioma growth and angiogenesis and enhances chemosensitivity by targeting R-Ras and N-Ras. ( Chen, Q; Jiang, BH; Jiang, C; Jiang, T; Kang, C; Li, C; Li, H; Liu, LZ; Liu, N; Liu, X; Qian, X; Shi, Z; Wang, L; Wang, X; You, Y, 2014)
"WBRT followed by IMBRT combined with concomitant TMZ is well tolerated, yielding an encouraging objective response rate; however, overall survival improves slightly comparing with RTOG 9508 randomized trial."1.40Whole brain radiation therapy followed by intensity-modulated boosting treatment combined with concomitant temozolomide for brain metastases from non-small-cell lung cancer. ( Jiang, Z; Leng, C; Liang, S; Liu, H; Lu, F; Lu, S; Qi, X; Shi, J; Wang, Q; Wang, S, 2014)
"Three scales, i."1.40Longitudinal quality of life data: a comparison of continuous and ordinal approaches. ( Albert, A; Bottomley, A; Coens, C; Donneau, AF; Mauer, M, 2014)
"Glioblastoma is the most prevalent primary brain tumor and is essentially universally fatal within 2 years of diagnosis."1.40Molecular targeting of TRF2 suppresses the growth and tumorigenesis of glioblastoma stem cells. ( Bai, Y; Flavahan, W; Lathia, JD; Mattson, MP; Rich, JN; Zhang, P, 2014)
"Temozolomide (TMZ) is an oral alkylating agent which is widely used in the treatment of GBM following surgery."1.40miR-128 and miR-149 enhance the chemosensitivity of temozolomide by Rap1B-mediated cytoskeletal remodeling in glioblastoma. ( Cui, Y; Lei, Q; Li, G; She, X; Wang, Z; Wu, M; Xiang, J; Xu, G; Yu, Z, 2014)
"Non-invasive monitoring of response to treatment of glioblastoma (GB) is nowadays carried out using MRI."1.40Molecular imaging coupled to pattern recognition distinguishes response to temozolomide in preclinical glioblastoma. ( Arús, C; Candiota, AP; Delgado-Goñi, T; Julià-Sapé, M; Pumarola, M, 2014)
"GBM is a primary brain tumor known to frequently demonstrate resistance to apoptosis-inducing therapeutics."1.40SapC-DOPS-induced lysosomal cell death synergizes with TMZ in glioblastoma. ( Chakravarti, A; Chu, Z; Denton, N; Dmitrieva, N; Hardcastle, J; Jacob, NK; Kaur, B; Kwon, CH; Marsh, R; Meisen, WH; Qi, X; Thorne, AH; Van Meir, EG; Wojton, J, 2014)
" In the present work, TMZ was combined with a specific SKI, and the cytotoxic effect of each drug alone or in combination was tested on GBM cell lines."1.40A sphingosine kinase inhibitor combined with temozolomide induces glioblastoma cell death through accumulation of dihydrosphingosine and dihydroceramide, endoplasmic reticulum stress and autophagy. ( Choi, J; Kopp-Schneider, A; Noack, J; Régnier-Vigouroux, A; Richter, K, 2014)
"Metastases represent the most common brain tumors in adults."1.40Intracranial microcapsule chemotherapy delivery for the localized treatment of rodent metastatic breast adenocarcinoma in the brain. ( Brem, H; Cima, M; Grossman, R; Hwang, L; Langer, R; Masi, B; Patta, Y; Scott, A; Spencer, K; Tyler, B; Upadhyay, UM; Wicks, R, 2014)
"Malignant glioma is a severe type of brain tumor with a poor prognosis and few options for therapy."1.40Glutathione depletion sensitizes cisplatin- and temozolomide-resistant glioma cells in vitro and in vivo. ( Belizário, JE; de Andrade-Lima, LC; Garcia, CC; Menck, CF; Munford, V; Quinet, A; Rocha, CR; Vieira, DB, 2014)
"Glioblastoma are highly aggressive brain tumors with poor prognosis."1.40Suppressor of fused (Sufu) represses Gli1 transcription and nuclear accumulation, inhibits glioma cell proliferation, invasion and vasculogenic mimicry, improving glioma chemo-sensitivity and prognosis. ( Cai, J; Chang, L; Chen, L; Cui, Y; Dou, Z; Du, W; Jiang, C; Liu, X; Liu, Y; Wang, G; Wang, H; Wang, X; Yi, L; Zhang, P, 2014)
"Here, we propose a new strategy to treat glioblastoma based on transferrin (Tf)-targeted self-assembled nanoparticles (NPs) incorporating zoledronic acid (ZOL) (NPs-ZOL-Tf)."1.40Medical treatment of orthotopic glioblastoma with transferrin-conjugated nanoparticles encapsulating zoledronic acid. ( Artuso, S; Balestrieri, ML; Caraglia, M; De Rosa, G; Leonetti, C; Luce, A; Lusa, S; Porru, M; Salzano, G; Stoppacciaro, A; Zappavigna, S, 2014)
" In a human GBM xenograft model, a single daily dosage of MB does not activate AMP-activated protein kinase signaling, and no tumor regression was observed."1.39Reversing the Warburg effect as a treatment for glioblastoma. ( Bigner, DD; Choudhury, GR; Ghorpade, A; Keir, ST; Li, W; Liu, R; Poteet, E; Ryou, MG; Simpkins, JW; Tang, L; Wen, Y; Winters, A; Yan, H; Yang, SH; Yuan, F, 2013)
"Clinical presentation of gliomatosis cerebri is variable and depends on the degree, extent, and location of cortical involvement."1.39Bilateral ptosis as initial presentation of gliomatosis cerebri: case report. ( Braca, J; Kovanda, T; Prabhu, V, 2013)
" Sufficient information on steroid dosing was available in 72 patients included in the final analysis."1.39Steroid management in newly diagnosed glioblastoma. ( Deangelis, LM; Deutsch, MB; Lassman, AB; Panageas, KS, 2013)
"Temozolomide was used almost exclusively during CRT (94."1.39Outcomes for patients with anaplastic astrocytoma treated with chemoradiation, radiation therapy alone or radiation therapy followed by chemotherapy: a retrospective review within the era of temozolomide. ( Cahill, D; Gilbert, MR; Lei, X; Shonka, NA; Smith, L; Theeler, B; Yung, A, 2013)
"Temozolomide (TMZ) is an alkylating agent shown to prolong survival in patients with high grade glioma and is routinely used to treat melanoma brain metastases."1.39Myeloablative temozolomide enhances CD8⁺ T-cell responses to vaccine and is required for efficacy against brain tumors in mice. ( Archer, GE; Bigner, DD; Choi, BD; Cui, X; Flores, C; Herndon, JE; Johnson, LA; Mitchell, DA; Sampson, JH; Sanchez-Perez, LA; Schmittling, RJ; Snyder, D, 2013)
"Glioblastoma multiforme is the most common lethal brain tumor in human adults, with no major therapeutic breakthroughs in recent decades."1.39Organotypic slice cultures of human glioblastoma reveal different susceptibilities to treatments. ( Bauer, M; Bechmann, I; Dehghani, F; Durante, M; Gaunitz, F; Giese, A; Gutenberg, A; Hellwig, C; Meixensberger, J; Merz, F; Renner, C; Schäfer, M; Schopow, K; Stöcker, H; Taucher-Scholz, G, 2013)
"Glioblastoma multiforme is the most aggressive primary brain tumour."1.39Apoptosis induction in human glioblastoma multiforme T98G cells upon temozolomide and quercetin treatment. ( Bądziul, D; Jakubowicz-Gil, J; Langner, E; Rzeski, W; Wertel, I, 2013)
"C6 rat gliomas were incubated with low-dose TMZ to induce chemoresistance."1.39Trans-1-amino-3-18F-fluorocyclobutanecarboxylic acid (anti-18F-FACBC) is a feasible alternative to 11C-methyl-L-methionine and magnetic resonance imaging for monitoring treatment response in gliomas. ( Baden, A; Doi, Y; Kanagawa, M; Mizoi, K; Oka, S; Ono, T; Sasajima, T; Shimada, N, 2013)
"The presence of subcutaneous metastases raised the suspicion for metastatic melanoma; however, pathological confirmation remained the ultimate tool to reach the final diagnosis."1.39Melanoma of unknown primary origin presenting as a rapidly enlarging adrenal mass. ( Ejaz, S; Habra, MA; Henderson, SA; Shawa, H, 2013)
"Glioblastoma is the most lethal brain cancer."1.39Antitumor activity of (2E,5Z)-5-(2-hydroxybenzylidene)-2-((4-phenoxyphenyl)imino) thiazolidin-4-one, a novel microtubule-depolymerizing agent, in U87MG human glioblastoma cells and corresponding mouse xenograft model. ( Li, C; Li, X; Liu, X; Yan, B; Zhang, Q; Zhou, H, 2013)
"Temozolomide (TMZ) is an alkylating agent primarily used to treat tumors of the central nervous system."1.39Central diabetes insipidus: a previously unreported side effect of temozolomide. ( Faje, AT; Klibanski, A; Makimura, H; Miller, KK; Nachtigall, L; Wexler, D, 2013)
"Glioblastoma is a highly aggressive malignant disease with notable resistance to chemotherapy."1.39High expression of leptin receptor leads to temozolomide resistance with exhibiting stem/progenitor cell features in gliobalastoma. ( Han, G; Hu, X; Li, Y; Liu, J; Wang, L; Yue, Z; Zhao, R; Zhao, W; Zhou, X, 2013)
" In the present analysis, we retrospectively investigated the feasibility and effectiveness of bevacizumab combined with ICE in patients with glioblastoma at second relapse during ICE treatment."1.39Retrospective analysis of bevacizumab in combination with ifosfamide, carboplatin, and etoposide in patients with second recurrence of glioblastoma. ( Arakawa, Y; Fujimoto, K; Kikuchi, T; Kunieda, T; Miyamoto, S; Mizowaki, T; Murata, D; Takagi, Y; Takahashi, JC, 2013)
"Previously, it has been shown that treatment of glioma cells with temozolomide (TMZ) and radiation (XRT) induces the expression of metalloproteinase 14 (MMP14)."1.39Inhibition of MMP14 potentiates the therapeutic effect of temozolomide and radiation in gliomas. ( Auffinger, B; Baryshnikov, AY; Borovjagin, A; Dey, M; Guo, D; Han, Y; Kim, CK; Lesniak, MS; Pytel, P; Sarvaiya, P; Thaci, B; Ulasov, I; Yi, R; Zhang, L, 2013)
"Anaplastic ependymomas are rare tumors in adult patients."1.39Cisplatin and temozolomide combination in the treatment of supratentorial anaplastic ependymoma. ( Bellu, L; Della Puppa, A; Gardiman, MP; Lombardi, G; Pambuku, A; Pomerri, F; Rumanò, L; Zagonel, V, 2013)
"Pseudoprogression (PP) during adjuvant treatment of glioblastoma (GBM) is frequent and is a clinically and radiologically challenging problem."1.39Is there pseudoprogression in secondary glioblastomas? ( Cerhova, J; Chakravarti, A; Engellandt, K; Geiger, KD; Juratli, TA; Krex, D; Lautenschlaeger, T; Schackert, G; von Kummer, R, 2013)
"We analyzed the data of 210 patients treated for glioblastoma between 2005 and 2013."1.39[Results of postoperative radiochemotherapy of glioblastoma multiforme]. ( Bagó, A; Bajcsay, A; Fedorcsák, I; Kásler, M; Lövey, J; Mangel, L; Sipos, L, 2013)
"Temozolomide is an attractive candidate treatment in neuroblastoma with methylated MGMT, especially in central nervous system relapsed cases."1.39Efficacy of temozolomide in a central nervous system relapse of neuroblastoma with O 6 -methylguanine methyltransferase (MGMT) promoter methylation. ( Marutsuka, K; Moritake, H; Nunoi, H; Shimonodan, H; Takeshima, H; Yamada, A; Yokogami, K, 2013)
"Glioblastoma multiforme is the most common malignant central nervous system tumor, and also among the most difficult to treat due to a lack of response to chemotherapeutics."1.39Targeted nitric oxide delivery preferentially induces glioma cell chemosensitivity via altered p53 and O(6) -methylguanine-DNA methyltransferase activity. ( Payne, CA; Safdar, S; Taite, LJ; Tu, NH, 2013)
" This drug combination significantly impaired the sphere-forming ability of GSCs in vitro and tumor formation in vivo, leading to increase in the overall survival of mice bearing orthotopic inoculation of GSCs."1.39Effective elimination of cancer stem cells by a novel drug combination strategy. ( Chen, G; Colman, H; Feng, L; Huang, P; Keating, MJ; Li, X; Wang, F; Wang, J; Wang, L; Xu, RH; Yuan, S; Zhang, H, 2013)
"Angiocentric glioma is a recently recognized benign brain tumor with unknown histogenesis."1.39Malignant glioma with angiocentric features. ( Lu, JQ; Mehta, V; Patel, S; Pugh, J; Wilson, BA, 2013)
"Gliosarcoma was more common in males (n = 31, 67."1.39Temozolomide use in adult patients with gliosarcoma: an evolving clinical practice. ( Brown, PD; Gilbert, MR; McAleer, MF; Prabhu, SS; Walker, GV, 2013)
"More effective drugs for brain cancer and brain metastasis can be screened and can be identified with this technology."1.39Subcellular real-time imaging of the efficacy of temozolomide on cancer cells in the brain of live mice. ( Bouvet, M; Chishima, T; Endo, I; Hoffman, RM; Momiyama, M; Suetsugu, A, 2013)
"We here show that glioblastomas are capable to downregulate MGMT expression independently of promoter methylation by elongation of the 3'-UTR of the mRNA, rendering the alternatively polyadenylated transcript susceptible to miRNA-mediated suppression."1.39In human glioblastomas transcript elongation by alternative polyadenylation and miRNA targeting is a potent mechanism of MGMT silencing. ( Egensperger, R; Hinske, LC; Hoefig, K; Kreth, FW; Kreth, S; Limbeck, E; Schütz, SV; Thon, N, 2013)
"The tumor was partially resected and anaplastic astrocytoma was diagnosed."1.38Hepatitis B virus reactivation associated with temozolomide for malignant glioma: a case report and recommendation for prophylaxis. ( Fujimoto, Y; Hashimoto, N; Kagawa, N; Kinoshita, M; Miyazaki, Y; Takehara, T; Tanaka, S; Yakushijin, T; Yoshimine, T, 2012)
"Temozolomide is an active drug against gliomas in adults."1.38Temozolomide in relapsed pediatric brain tumors: 14 cases from a single center. ( Akyüz, C; Büyükpamukçu, M; Demir, HA; Kutluk, T; Varan, A; Yalçin, B, 2012)
"Glioblastoma is the most common and most malignant primary brain tumor in adults."1.38Glioblastoma: clinical characteristics, prognostic factors and survival in 492 patients. ( Hedderich, J; Mehdorn, HM; Nabavi, A; Stark, AM; van de Bergh, J, 2012)
"Thrombocytopenia was operationalized as a continuous platelet count and a dichotomic variable (cut-off <100."1.38Impact of antiepileptic drugs on thrombocytopenia in glioblastoma patients treated with standard chemoradiotherapy. ( Blasco, J; Bruna, J; Gil, M; Graus, F; Pineda, E; Simó, M; Velasco, R; Verger, E, 2012)
" These results suggest that GBMs with EGFR amplification are a heterogenous group of tumors and that behavior might differ according to the degree of amplification, although not in a straightforward dose-response manner."1.38Paradoxical relationship between the degree of EGFR amplification and outcome in glioblastomas. ( Bortoluzzi, S; Cieply, K; Fardo, DW; Hamilton, RL; Hobbs, J; Horbinski, C; Nikiforova, MN, 2012)
"Primary malignant brain tumors (BT) are the most common and aggressive malignant brain tumor."1.38Intracranial MEMS based temozolomide delivery in a 9L rat gliosarcoma model. ( Bow, H; Brem, H; Cima, MJ; Langer, R; Masi, BC; Tyler, BM; Wicks, RT; Xue, Y, 2012)
" These data reassuringly suggest that BEV does not significantly change the ECF tumor concentrations of TMZ in either tumor-bearing or normal brain when dosed 36 h prior to TMZ."1.38The impact of bevacizumab on temozolomide concentrations in intracranial U87 gliomas. ( Blakeley, JO; Brastianos, H; Brem, H; Grossman, R; Rudek, MA; Tyler, B; Zadnik, P, 2012)
"Combining Gliadel wafers and radiochemotherapy with TMZ may carry the risk of increased adverse events (AE)."1.38Safety and efficacy of Gliadel wafers for newly diagnosed and recurrent glioblastoma. ( Anile, C; Balducci, M; Chiesa, S; De Bonis, P; Fiorentino, A; Maira, G; Mangiola, A; Pompucci, A, 2012)
"Glioblastoma multiforme is the most common primary malignant brain tumour, with a median survival of about one year."1.38A restricted cell population propagates glioblastoma growth after chemotherapy. ( Burns, DK; Chen, J; Kernie, SG; Li, Y; McKay, RM; Parada, LF; Yu, TS, 2012)
"The management of brain metastases (BM) from breast cancer (BC) needs to be improved, and new therapeutic strategies are urgently requested."1.38Protracted low dose of oral vinorelbine and temozolomide with whole-brain radiotherapy in the treatment for breast cancer patients with brain metastases. ( Addeo, R; Caraglia, M; Carraturo, M; Cennamo, G; Iodice, P; Lombardi, A; Montella, L; Parlato, C; Prete, SD; Russo, P; Salzano, A; Sperlongano, P; Sperlongano, R; Vincenzi, B, 2012)
"These brain tumors are often resistant to chemotherapies like temozolomide (TMZ) and there are very few treatment options available to patients."1.38Disulfiram, a drug widely used to control alcoholism, suppresses the self-renewal of glioblastoma and over-rides resistance to temozolomide. ( Berns, R; Dunn, SE; Fotovati, A; Hu, K; Kast, RE; Kong, E; Lee, C; Luk, M; Pambid, M; Toyota, B; Toyota, E; Triscott, J; Yip, S, 2012)
"To report the serial development of oral mucositis following infusion of bevacizumab in a young woman with a malignant brain tumor and history of cutaneous psoriasis."1.38Bevacizumab-induced oral mucositis in background of cutaneous plaque-type psoriasis. ( Cuellar, S; Popa, AM; Radhakrishnan, L; Valla, K; Villano, JL, 2012)
"Temozolomide (TMZ) is a prodrug for an alkylating agent used for the treatment of malignant brain tumors."1.38An efficient and practical radiosynthesis of [11C]temozolomide. ( Carlin, SM; Hooker, JM; Moseley, CK; Neelamegam, R, 2012)
"Extracranial metastasis of primary brain tumors is rarely observed."1.38Breast metastasis of anaplastic oligodendroglioma: a case report. ( Alacacioglu, A; Canpolat, S; Coskun, A; Karatas, A; Oztekin, O; Postaci, H; Sop, G; Unal, S; Yurt, A, 2012)
"Temozolomide was prescribed, and a disease-free period of 2 years followed."1.37Case of atypical teratoid/rhabdoid tumor in an adult, with long survival. ( Ikeda, J; Kanno, H; Katoh, M; Kimura, T; Mahabir, R; Nagashima, K; Nishihara, H; Sawamura, Y; Takahashi, K; Tanaka, S; Tanino, M; Yoshinaga, T, 2011)
"All patients had seizure disorders that were treated with anticonvulsants."1.37Impact of temozolomide chemotherapy on seizure frequency in patients with low-grade gliomas. ( Moldovan, K; Pouratian, N; Schiff, D; Shaffrey, ME; Sherman, JH; Starke, RM; Yeoh, HK, 2011)
"Malignant gliomas are highly lethal tumors resistant to current therapies."1.37Lonafarnib (SCH66336) improves the activity of temozolomide and radiation for orthotopic malignant gliomas. ( Barnes, JW; Chaponis, D; Dellagatta, JL; Fast, E; Greene, ER; Kesari, S; Kieran, MW; Kung, AL; Panagrahy, D; Ramakrishna, N; Sauvageot, C; Stiles, C; Wen, PY, 2011)
" We evaluated the preclinical potential of a novel, orally bioavailable PI3K/mTOR dual inhibitor (XL765) in in vitro and in vivo studies."1.37Inhibition of PI3K/mTOR pathways in glioblastoma and implications for combination therapy with temozolomide. ( Aftab, DT; Berger, MS; Haas-Kogan, DA; James, CD; Mueller, S; Ozawa, T; Polley, MY; Prados, MD; Prasad, G; Sottero, T; Weiss, WA; Yang, X, 2011)
"The long-term TMZ-treated astroglioma cells, but not the Hs683 oligodendroglioma cells, developed in vivo a certain level of resistance to TMZ, which correlated with the up- regulation of CXCL2, CXCL3 and CXCL8 expression in the U373 and T98G astroglioma cells."1.37Temozolomide-induced modification of the CXC chemokine network in experimental gliomas. ( Berger, W; Bruyère, C; Kast, RE; Kiss, R; Lefranc, F; Lonez, C; Mijatovic, T; Ruysschaert, JM; Spiegl-Kreinecker, S, 2011)
"Metformin or olanzapine have been shown independently to enhance AMPK activation."1.37Can the therapeutic effects of temozolomide be potentiated by stimulating AMP-activated protein kinase with olanzepine and metformin? ( Halatsch, ME; Karpel-Massler, G; Kast, RE, 2011)
"The prognostic value of postoperative residual tumor volume in FET PET, TBR(mean,) TBR(max) and Gd-volume was evaluated using Kaplan-Maier estimates for disease-free survival (DFS) and overall survival (OS)."1.37Prognostic impact of postoperative, pre-irradiation (18)F-fluoroethyl-l-tyrosine uptake in glioblastoma patients treated with radiochemotherapy. ( Coenen, HH; Eble, MJ; Galldiks, N; Herzog, H; Holy, R; Kaiser, HJ; Langen, KJ; Pinkawa, M; Piroth, MD; Stoffels, G, 2011)
"Intracranial anaplastic ependymomas are a very rare entity within the group of adult CNS neoplasms."1.37Response to temozolomide in supratentorial multifocal recurrence of malignant ependymoma. ( Freyschlag, CF; Lohr, F; Schmieder, K; Seiz, M; Thomé, C; Tuettenberg, J, 2011)
"Cediranib is a highly potent receptor tyrosine kinase inhibitor that inhibits all three VEGF receptors."1.37Cediranib enhances control of wild type EGFR and EGFRvIII-expressing gliomas through potentiating temozolomide, but not through radiosensitization: implications for the clinic. ( Andersen, B; Dicker, AP; Lawrence, RY; Liu, Y; Wachsberger, PR; Xia, X, 2011)
"Temozolomide is an effective treatment for seizure control in patients with brain tumors."1.37Seizure control: a secondary benefit of chemotherapeutic temozolomide in brain cancer patients. ( Hu, A; Kesari, S; Kim, RY; Lee, JW; Nguyen, A; Xu, Z, 2011)
"Communicating hydrocephalus is an uncommon complication in patients treated for glioblastoma multiforme (GBM)."1.37Communicating hydrocephalus following surgery and adjuvant radiochemotherapy for glioblastoma. ( Bianchi, F; D'Alessandris, QG; Doglietto, F; Fernandez, E; Lauretti, L; Maira, G; Montano, N; Pallini, R, 2011)
"Oral temozolomide (TMZ) was administered in combination with mFc-endostatin to determine if there was a beneficial synergistic effect."1.37Improvement in the standard treatment for experimental glioma by fusing antibody Fc domain to endostatin. ( Brem, H; Grossman, R; Hwang, L; Javaherian, K; Lal, B; Tyler, B; Zadnik, P, 2011)
" The growing body of evidence demonstrating the clinical importance of O6-methylguanine methyltransferase (MGMT) has generated a considerable interest in the exploration of strategies to overcome MGMT-mediated resistance to alkylating agents; for example protracted administration of Temozolomide (TMZ) may result in more extensive and sustained depletion of MGMT; for this reason a variety of dosing schedules that increase the duration of exposure and the cumulative dose of TMZ are being investigated for the treatment of patient with recurrent malignant glioma after standard treatment."1.37Rechallenge with temozolomide in recurrent glioma. ( Botturi, A; Fariselli, L; Ferrari, D; Gaviani, P; Lamperti, E; Salmaggi, A; Silvani, A; Simonetti, G, 2011)
"Our results of combined treatment of brain metastases are presented and available approaches to brain irradiation and chemotherapy are discussed."1.37[Brain metastasis in breast cancer]. ( Ivanov, VG; Korytova, LI; Masliukova, EA; Meshechkin, AV; Zhabuna, RM, 2011)
"Sixty-eight patients with brain tumors were studied (60% high-grade glioma)."1.36Comparing neuropsychological tasks to optimize brief cognitive batteries for brain tumor clinical trials. ( Anderson, SK; Brown, PD; Cerhan, JH; Lageman, SK; Locke, DE; Wu, W, 2010)
"MGMT expression in brain metastases was significantly correlated with better survival."1.36O(6)-Methylguanine-DNA methyltransferase expression and prognostic value in brain metastases of lung cancers. ( Cheng, AL; Kuo, KT; Kuo, LT; Lee, WC; Lin, CH; Lin, YT; Lu, YS; Tasi, JC; Tseng, HM; Tseng, SH; Tu, YK; Wu, PF; Wu, RM; Yang, CH, 2010)
"Gliomas account for more than 50% of all primary brain tumors."1.36Long-term temozolomide treatment induces marked amino metabolism modifications and an increase in TMZ sensitivity in Hs683 oligodendroglioma cells. ( Bontempi, G; Bruyère, C; Decaestecker, C; Dubois, J; Haibe-Kains, B; Kiss, R; Lamoral-Theys, D; Le Calvé, B; Le Mercier, M; Lefranc, F; Rynkowski, MA, 2010)
"Poor drug delivery to brain tumors caused by aberrant tumor vasculature and a partly intact blood-brain barrier (BBB) and blood-brain tumor barrier (BTB) can significantly impair the efficacy of chemotherapy."1.36Noninvasive detection of temozolomide in brain tumor xenografts by magnetic resonance spectroscopy. ( Artemov, D; Holm, DA; Kato, Y; Okollie, B, 2010)
"Concurrent treatment of the glioma cell line U87-MG with siRNA 1 and temozolomide (TMZ) resulted in a 13-fold reduction in the dose of TMZ required to achieve a similar effect if TMZ was used alone."1.36Can hsp90alpha-targeted siRNA combined with TMZ be a future therapy for glioma? ( Cruickshanks, N; Munje, C; Patel, R; Shervington, A; Shervington, L; Thakkar, D, 2010)
"Glioblastoma multiforme is the most common and most malignant primary brain tumour."1.36Far-distant metastases along the CSF pathway of glioblastoma multiforme during continuous low-dose chemotherapy with temozolomide and celecoxib. ( Freyschlag, CF; Nölte, I; Pechlivanis, I; Schmieder, K; Seiz, M; Tuettenberg, J; Vajkoczy, P, 2010)
"Glioblastoma multiforme is the most commonly diagnosed malignant primary brain tumour in adults."1.36Inhibition of metalloproteinases derived from tumours: new insights in the treatment of human glioblastoma. ( Bendinelli, S; Casalini, F; Costa, B; Da Pozzo, E; Da Settimo, F; Gabelloni, P; Martini, C; Nuti, E; Orlandini, E; Rossello, A, 2010)
"Temozolomide (TMZ) is a recently introduced alkylating agent that has yielded significant benefits and become a key agent in the treatment of high-grade gliomas."1.36Gene expression profiling predicts response to temozolomide in malignant gliomas. ( Fukushima, T; Katayama, Y; Naruse, N; Ogino, A; Ohta, T; Okamoto, Y; Sano, E; Tsumoto, K; Watanabe, T; Yachi, K; Yoshino, A, 2010)
"High-grade gliomas are among the most lethal of all cancers."1.36Embryonic stem cell (ESC)-mediated transgene delivery induces growth suppression, apoptosis and radiosensitization, and overcomes temozolomide resistance in malignant gliomas. ( Binello, E; Emdad, L; Germano, IM; Qadeer, ZA; Uzzaman, M, 2010)
"Glioblastomas (GBM) are lethal brain tumors that are highly resistant to therapy."1.36PTEN loss compromises homologous recombination repair in astrocytes: implications for glioblastoma therapy with temozolomide or poly(ADP-ribose) polymerase inhibitors. ( Bachoo, RM; Burma, S; Camacho, CV; Hahm, B; McEllin, B; Mukherjee, B; Tomimatsu, N, 2010)
"A major barrier to progress in treatment of glioblastoma is the relative inaccessibility of tumors to chemotherapeutic agents."1.36Convection-enhanced delivery of a synthetic retinoid Am80, loaded into polymeric micelles, prolongs the survival of rats bearing intracranial glioblastoma xenografts. ( Kumabe, T; Nishihara, M; Saito, R; Satoh, T; Sonoda, Y; Sugiyama, S; Tominaga, T; Yamashita, Y; Yokosawa, M; Yokoyama, M, 2010)
"Glioblastoma is the most common primary malignant brain tumor; however, glioblastoma in children is less common than in adults, and little is known about its clinical outcome in children."1.36Long-term outcomes in children with glioblastoma. ( Ahn, HS; Cho, BK; Kim, DG; Kim, IH; Kim, SK; Lee, JY; Park, SH; Phi, JH; Song, KS; Wang, KC, 2010)
"A 33-year-old woman presented with rare brain metastases from undifferentiated high-grade sarcoma manifesting as headache and vomiting."1.36Brain metastasis of undifferentiated sarcoma and response to temozolomide treatment. Case report. ( Arai, A; Itoh, T; Kanomata, N; Kawamura, A; Kohmura, E; Nishihara, M; Sasayama, T; Tanaka, H, 2010)
"Malignant astrocytic brain tumors are among the most lethal cancers."1.36Non-stem cell origin for oligodendroglioma. ( Auvergne, R; Ayers-Ringler, J; Berger, MS; Bergers, G; Goldenberg, DD; Goldman, SA; Itsara, M; McKnight, TR; Nguyen, KN; Nishiyama, A; Persson, AI; Petritsch, C; Sim, FJ; Stallcup, WB; Swartling, FJ; Vandenberg, SR; Weiss, WA; Yakovenko, S, 2010)
"6% and 1/6 rat survived more than 1 year in case of MRT combined with gadolinium injection."1.35Enhancement of survival of 9L gliosarcoma bearing rats following intracerebral delivery of drugs in combination with microbeam radiation therapy. ( Bräuer-Krisch, E; Bravin, A; Keyriläinen, J; Le Duc, G; Régnard, P; Troprès, I, 2008)
"Temozolomide is a relatively new chemotherapeutic agent frequently associated with selective CD4+ T-lymphocytopenia."1.35Disseminated salmonellosis in a patient treated with temozolomide. ( Adachi, J; Georgescu, G; Isola, IM; Rolston, K; Youssef, S, 2008)
"Bortezomib proved to be a more potent inductor of apoptosis than gefitinib and alkylating agents."1.35Cytotoxic and apoptotic effects of bortezomib and gefitinib compared to alkylating agents on human glioblastoma cells. ( Cambar, J; De Giorgi, F; Ichas, F; L'Azou, B; Passagne, I; Pédeboscq, S; Pometan, JP, 2008)
"Temozolomide (TMZ) is a cytotoxic agent of the imidazotetrazine class, chemically related to dacarbazine."1.35Tuberculosis in a patient on temozolomide: a case report. ( de Barros e Silva, MJ; de Paiva, TF; Fanelli, MF; Gimenes, DL; Rinck, JA, 2009)
"Temozolomide is an effective alkylating agent that is increasingly used for the treatment of pediatric brain tumors."1.35Treatment-related myelodysplastic syndrome after temozolomide use in a child: first report. ( Auger, N; Bhangoo, R; Da Costa, L; Dufour, C; Grill, J; Jullien, M, 2008)
"As favorable outcomes from malignant brain tumors remain limited by poor survival and treatment-related toxicity, novel approaches to cure are essential."1.35Targeted inhibition of cyclic AMP phosphodiesterase-4 promotes brain tumor regression. ( Goldhoff, P; Hope, A; Jackson, E; Limbrick, DD; Perry, A; Piwnica-Worms, D; Rubin, JB; Warrington, NM; Woerner, BM, 2008)
"We report a case of pituitary carcinoma with multiple craniospinal metastases in a child."1.35Pituitary carcinoma presenting with multiple metastases: case report. ( Cayli, SR; Guzel, A; Guzel, E; Sav, A; Senturk, S; Tatli, M, 2008)
" The system analysis technique, embodied in the convolution integral, generated an impulse response function that, when convolved with temozolomide plasma concentration input functions, yielded predicted normal brain and brain tumor temozolomide concentration profiles for different temozolomide dosing regimens (75-200 mg/m(2)/d)."1.35A new model for prediction of drug distribution in tumor and normal tissues: pharmacokinetics of temozolomide in glioma patients. ( Aboagye, EO; Brock, CS; Gallo, JM; Price, PM; Rosso, L; Saleem, A; Turkheimer, FE, 2009)
"Glioblastoma multiforme is a primary malignant brain tumor with a prognosis of typically less than 2 years."1.35Tonsillary carcinoma after temozolomide treatment for glioblastoma multiforme: treatment-related or dual-pathology? ( Binello, E; Germano, IM, 2009)
"Cilengitide is a cyclic peptide antagonist of integrins alphavbeta3 and alphavbeta5 that is currently being evaluated as a novel therapeutic agent for recurrent and newly diagnosed glioblastoma."1.35Cilengitide modulates attachment and viability of human glioma cells, but not sensitivity to irradiation or temozolomide in vitro. ( Adams, B; Maurer, GD; Stupp, R; Tabatabai, G; Tritschler, I; Weller, M; Wick, W, 2009)
"First clinical reports on treating brain metastases with temozolomide describe varying effects."1.35Homogeneous MGMT immunoreactivity correlates with an unmethylated MGMT promoter status in brain metastases of various solid tumors. ( Heppner, FL; Ingold, B; Moch, H; Schraml, P, 2009)
"We report the case of a patient with primary brain tumor who developed cytomegalovirus associated colonic pseudotumor as an opportunistic infection while receiving chemotherapy with Temozolomide and radiation."1.35Cytomegalovirus associated colonic pseudotumor: a consequence of iatrogenic immunosuppression in a patient with primary brain tumor receiving radiation and temozolomide. ( De Jesus, A; Grossman, SA; Paun, O, 2009)
"Carmustine wafer was not an independent predictor (P=."1.35Overall survival of newly diagnosed glioblastoma patients receiving carmustine wafers followed by radiation and concurrent temozolomide plus rotational multiagent chemotherapy. ( Affronti, ML; Bigner, DD; Desjardins, A; Friedman, AH; Friedman, HS; Heery, CR; Herndon, JE; Reardon, DA; Rich, JN; Vredenburgh, JJ, 2009)
" After irradiation of the symptomatic sites, intrathecal liposomal Ara-C every 2-4 weeks was combined with temozolomide 100 mg/m(2) day 1-5/7."1.35Neoplastic meningitis from breast cancer: feasibility and activity of long-term intrathecal liposomal Ara-C combined with dose-dense temozolomide. ( Buhk, JH; Hoffmann, AL; Strik, H, 2009)
"Glioblastomas are highly aggressive primary brain tumors."1.35Antiangiogenic compounds interfere with chemotherapy of brain tumors due to vessel normalization. ( Claes, A; Heerschap, A; Jeuken, J; Leenders, WP; Maass, C; Wesseling, P, 2008)
" The effect of ZD6474, a potent inhibitor of VEGF-receptor-2, was evaluated in combination with either radiotherapy or temozolomide."1.35Effects of the VEGFR inhibitor ZD6474 in combination with radiotherapy and temozolomide in an orthotopic glioma model. ( Bergenheim, AT; Bergström, P; Henriksson, R; Johansson, M; Sandström, M, 2008)
"Temozolomide has become the standard of care in newly diagnosed glioblastoma."1.35[Chemotherapy for brain tumors in adult patients]. ( Weller, M, 2008)
"Astroblastoma is a historically traded microscopic diagnosis to denote a rare neuroepithelial tumor of uncertain nosology, involving a distinctive pattern of pseudorosette arrangement of neoplastic cells."1.35Astroblastoma with rhabdoid features and favorable long-term outcome: report of a case with a 12-year follow-up. ( El-Koussy, M; Fathi, AR; Kappeler, A; Mariani, L; Novoa, E; Vajtai, I, 2008)
" Thus, the implantation of BCNU wafers prior to TMZ and radiotherapy appears safe in newly diagnosed GBM patients."1.35A retrospective study of the safety of BCNU wafers with concurrent temozolomide and radiotherapy and adjuvant temozolomide for newly diagnosed glioblastoma patients. ( Mitchell, SB; Pan, E; Tsai, JS, 2008)
"Temozolomide is a proautophagic (type II programmed cell death) drug and can thus circumvent part of the glioblastoma resistance to apoptosis."1.35[The sodium pump could constitute a new target to combat glioblastomas]. ( Kiss, R; Lefranc, F; Mijatovic, T, 2008)
"Temozolomide (TMZ) is used for treating glioblastoma."1.35Modulatory effects of acetazolomide and dexamethasone on temozolomide-mediated apoptosis in human glioblastoma T98G and U87MG cells. ( Banik, NL; Das, A; Ray, SK, 2008)
"We studied 53 MG-PNETs in patients from 12 to 80 years of age (median = 54 years)."1.35Malignant gliomas with primitive neuroectodermal tumor-like components: a clinicopathologic and genetic study of 53 cases. ( Burger, PC; Cochran, EJ; Gujrati, M; Holland, EC; Huse, JT; Jost, SC; Miller, CR; Perry, A; Qian, J; Raghavan, R; Rosenblum, MK; Scheithauer, BW; Zambrano, SC, 2009)
"The anterior temporal lesion was a ganglioglioma and did not recur."1.34Ganglioglioma occurring with glioblastoma multiforme: separate lesions or the same lesion? ( Dickerman, RD; Howes, G; Lee, JM; Nardone, EM; Stevens, QE, 2007)
" Three patients (12%) were changed to standard temozolomide dosing due to side effects, including intractable nausea (n = 2) and multiple cytopenias (n = 1)."1.34Toxicity and efficacy of protracted low dose temozolomide for the treatment of low grade gliomas. ( Gasco, J; Pouratian, N; Schiff, D; Shaffrey, ME; Sherman, JH, 2007)
"Glioblastoma multiforme is a malignant astrocytic tumor characterized by rapid growth, extensive invasiveness and high vascularity."1.34Interindividual differences in anticancer drug cytotoxicity in primary human glioblastoma cells. ( Cambar, J; L'Azou, B; Liguoro, D; Pédeboscq, S; Pometan, JP, 2007)
" Although this approach is promising, there has not been any attempt to define optimal metronomic dosing regimens by integrating pharmacokinetic (PK) with pharmacodynamic (PD) measurements."1.34Preclinical pharmacokinetic and pharmacodynamic evaluation of metronomic and conventional temozolomide dosing regimens. ( Gallo, JM; Guo, P; Nuthalapati, S; Wang, X; Zhou, Q, 2007)
"Glioblastoma multiforme is characterised by invasive growth and frequent recurrence."1.34Dynamics of chemosensitivity and chromosomal instability in recurrent glioblastoma. ( Berger, W; Buchroithner, J; Fischer, J; Marosi, C; Micksche, M; Pichler, J; Pirker, C; Silye, R; Spiegl-Kreinecker, S, 2007)
"Glioblastomas are malignant brain tumors that are very difficult to cure, even with aggressive therapy consisting of surgery, chemotherapy, and radiation."1.34Phosphatase and tensin homologue deficiency in glioblastoma confers resistance to radiation and temozolomide that is reversed by the protease inhibitor nelfinavir. ( Bernhard, EJ; Cerniglia, GJ; Georgescu, MM; Gupta, AK; Hahn, SM; Jiang, Z; Maity, A; Mick, R; Pore, N, 2007)
"Temozolomide treatment of high-grade tv-a gliomas provided a 14-day growth delay compared with vehicle controls."1.34Magnetic resonance imaging determination of tumor grade and early response to temozolomide in a genetically engineered mouse model of glioma. ( Hambardzumyan, D; Holland, EC; Kreger, AR; Leopold, WR; McConville, P; Moody, JB; Rehemtulla, A; Ross, BD; Woolliscroft, MJ, 2007)
"Gliomas, the most common primary brain tumors, are diffusive and highly invasive."1.34Mathematical modeling of brain tumors: effects of radiotherapy and chemotherapy. ( Kohandel, M; Milosevic, M; Oza, A; Powathil, G; Sivaloganathan, S, 2007)
"For patients with anaplastic astrocytoma, the 12-month survival rate was 73%."1.34Salvage chemotherapy in progressive high-grade astrocytoma. ( See, SJ; Ty, A; Wong, MC, 2007)
"Temozolomide was administered at a dose of 200 mg/m(2) daily for 5 days, in a 4-week cycle."1.34Temozolomide in pediatric low-grade glioma. ( Ashley, DM; Coleman, LT; Downie, PA; Heath, JA; Khaw, SL, 2007)
"Brain metastases are an alarming complication of advanced melanoma, frequently contributing to patient demise."1.34Biochemotherapy of metastatic melanoma in patients with or without recently diagnosed brain metastases. ( Boucher, KM; Jensen, RL; Leachman, SA; Majer, M; Samlowski, WE; Shrieve, DC; Wang, M; Watson, GA, 2007)
" Because significant obstacles prevent making these measurements in humans, development of a predictive pharmacokinetic model would be of great value to the translation of preclinical data to the clinic."1.34Predicting human tumor drug concentrations from a preclinical pharmacokinetic model of temozolomide brain disposition. ( Gallo, JM; Guo, P; Kruh, GD; Vicini, P; Wang, X; Zhou, Q, 2007)
"The time-to-maximum plasma concentration (tmax) of TMZ was about 1 h and the elimination half-life of terminal excretion phase (t 1/2lambda z) was about 2 h."1.34Pharmacokinetic study of temozolomide on a daily-for-5-days schedule in Japanese patients with relapsed malignant gliomas: first study in Asians. ( Adachi, J; Aoki, T; Matsutani, M; Mishima, K; Mizutani, T; Nishikawa, R; Nojima, K, 2007)
"Sixty four patients with melanoma brain metastases were treated in our department within a 15-year period."1.33Cerebral metastases of malignant melanoma: contemporary treatment modalities and survival outcome. ( Bafaloukos, DI; Brountzos, EN; Kelekis, DA; Panagiotou, IE; Papathanasiou, MA, 2005)
"Perifosine is an oral Akt inhibitor which exerts a marked cytotoxic effect on human tumor cell lines, and is currently being tested in several phase II trials for treatment of major human cancers."1.33Perifosine inhibits multiple signaling pathways in glial progenitors and cooperates with temozolomide to arrest cell proliferation in gliomas in vivo. ( Holland, EC; Momota, H; Nerio, E, 2005)
"Surgical cure of glioblastomas is virtually impossible and their clinical course is mainly determined by the biologic behavior of the tumor cells and their response to radiation and chemotherapy."1.33Patients with high-grade gliomas harboring deletions of chromosomes 9p and 10q benefit from temozolomide treatment. ( Beerenwinkel, N; Feiden, W; Hartmann, C; Ketter, R; Lengauer, T; Meese, E; Rahnenführer, J; Steudel, WI; Stockhammer, F; Strowitzki, M; Urbschat, S; von Deimling, A; Wemmert, S; Zang, KD, 2005)
"At the time of the initial disease recurrence, 13 patients were readministered TMZ."1.33Salvage temozolomide for prior temozolomide responders. ( Abrey, LE; Demopoulos, A; Franceschi, E; Lassman, AB; Nolan, C; Omuro, AM, 2005)
"The ability of treatment to reduce melanoma metastatic spreading and invasion of the extracellular matrix was also tested."1.33Poly(ADP-ribose) glycohydrolase inhibitor as chemosensitiser of malignant melanoma for temozolomide. ( Forini, O; Gold, B; Graziani, G; Lacal, PM; Leonetti, C; Li, W; Muzi, A; Ruffini, F; Scarsella, M; Tentori, L; Vergati, M; Zhang, J, 2005)
"Grosstotal resection of an anaplastic astrocytoma was followed by chemotherapy with temozolomide and vincristine."1.33A congenital brain tumor associated with assisted in vitro fertilization. Case report. ( Danielpour, M; Das, A; Simmons, C, 2005)
"Gliomas are primary brain tumors associated with a poor prognosis partly due to resistance to conventional therapies."1.33Antiangiogenic agent, thalidomide increases the antitumor effect of single high dose irradiation (gamma knife radiosurgery) in the rat orthotopic glioma model. ( Itasaka, S; Kim, JT; Lee, JI; Nam, DH, 2006)
"Malignant gliomas have a very poor prognosis."1.33A hypermutation phenotype and somatic MSH6 mutations in recurrent human malignant gliomas after alkylator chemotherapy. ( Avis, T; Barthorpe, S; Batchelor, TT; Bignell, G; Brackenbury, L; Buck, G; Butler, A; Cahill, DP; Clements, J; Cole, J; Davies, H; Dicks, E; Easton, DF; Edkins, S; Forbes, S; Futreal, PA; Gorton, M; Gray, K; Greenman, C; Halliday, K; Harrison, R; Hills, K; Hinton, J; Hunter, C; Jenkinson, A; Jones, D; Kosmidou, V; Laman, R; Levine, KK; Louis, DN; Lugg, R; Menzies, A; Mueller, W; O'Meara, S; Parker, A; Perry, J; Petty, R; Raine, K; Richardson, D; Riggins, G; Roy, JE; Shepherd, R; Small, A; Smith, R; Solomon, H; Stephens, P; Stevens, C; Stratton, MR; Teague, J; Tofts, C; Varian, J; West, S; Widaa, S; Wooster, R; Yates, A, 2006)
"Temozolomide (TMZ) has shown efficacy in the treatment of metastatic melanoma."1.33Whole brain irradiation and temozolomide based chemotherapy in melanoma brain metastases. ( Castel, T; Conill, C; Domingo-Doménech, J; Gallego, R; Jorcano, S; Malvehy, J; Puig, S; Sánchez, M; Vilella, R, 2006)
"Tamoxifen and hypericin were able to greatly increase the growth-inhibitory and apoptosis-stimulatory potency of temozolomide via the downregulation of critical cell cycle-regulatory and prosurvival components."1.33Enhancement of glioblastoma cell killing by combination treatment with temozolomide and tamoxifen or hypericin. ( Chen, TC; Gupta, V; Hofman, FM; Kardosh, A; Liebes, LF; Schönthal, AH; Su, YS; Wang, W, 2006)
"We report a case of multiple gangliogliomas of the optic pathway in an 18-year-old boy."1.33Multiple gangliogliomas of the optic pathway. ( Dambatta, S; Grundy, PL; Vajramani, GV; Walker, M, 2006)
" Temozolomide, an orally bioavailable alkylating agent that crosses the blood-brain barrier, has activity against brain metastases from both small cell lung cancer (SCLC) and non-small cell lung cancer (NSCLC) when used as a single agent, but response rates are low."1.32Use of temozolomide with other cytotoxic chemotherapy in the treatment of patients with recurrent brain metastases from lung cancer. ( Ebert, BL; Niemierko, E; Salgia, R; Shaffer, K, 2003)
"Temozolomide (TMZ) is a chemotherapeutic agent used in the treatment of high-grade brain tumors."1.32Formation of DNA adducts and induction of lacI mutations in Big Blue Rat-2 cells treated with temozolomide: implications for the treatment of low-grade adult and pediatric brain tumors. ( Berger, MS; Bodell, WJ; Gaikwad, NW; Miller, D, 2003)
"Temozolomide has shown antineoplastic activity against malignant gliomas and more recently was beneficial in one patient with gliomatosis cerebri."1.32Gliomatosis cerebri: clinical, neurochemical and neuroradiological response to temozolomide administration. ( Ambrosetto, P; Barbiroli, B; Cortelli, P; Crinò, L; Franceschi, E; Lodi, R; Setola, E; Tonon, C, 2003)
"Temozolomide (TMZ) displays efficacy for the treatment of metastatic melanoma."1.32[Temozolomide in patients with melanoma brain metastases treated with whole brain irradiation]. ( Castel, T; Conill, C; Fernández-Ibiza, J; Malvehy, J; Puig, S; Sánchez, M, 2004)
"Secondary anaplastic oligodendroglioma patients were younger than patients with de novo anaplastic oligodendrogliomas."1.32Long-term outcome of oligodendrogliomas. ( Bourg, V; Chanalet, S; Chatel, M; Fontaine, D; Frenay, M; Lebrun, C; Lonjon, M; Michiels, JF; Paquis, P; Ramaioli, A; Vandenbos, F, 2004)
" The population pharmacokinetic analysis was performed with nonlinear mixed-effect modeling software."1.32Plasma and cerebrospinal fluid population pharmacokinetics of temozolomide in malignant glioma patients. ( Buclin, T; Csajka, C; Decosterd, LA; Lejeune, F; Leyvraz, S; Ostermann, S; Stupp, R, 2004)
" In this work we investigated the effect of association of temozolomide (TMZ), an orally bioavailable alkylating agent, with three chemotherapeutic drugs, liposomal doxorubicin (DOXO), cis-platinum (CDDP)."1.32Effect of association of temozolomide with other chemotherapic agents on cell growth inhibition in glioma cell lines. ( Balzarotti, M; Boiardi, A; Calatozzolo, C; Ciusani, E; Croci, D; Salmaggi, A, 2004)
"Temozolomide (TMZ) has demonstrated activity and acceptable toxicity for the treatment of recurrent high-grade gliomas in prospective phase II studies."1.32Temozolomide for the treatment of recurrent supratentorial glioma: results of a compassionate use program in Belgium. ( Branle, F; Everaert, E; Joosens, E; Menten, J; Neyns, B; Strauven, T, 2004)
"Temozolomide (TMZ) is a methylating agent with promising antitumor efficacy for the treatment of melanomas and intermediate-grade gliomas."1.32The piperidine nitroxide Tempol potentiates the cytotoxic effects of temozolomide in human glioblastoma cells. ( Cereda, E; Gariboldi, MB; Monti, E; Ravizza, R, 2004)
" To that end, a novel method, based on physiologically based hybrid pharmacokinetic models, is presented to predict human tumor drug concentrations."1.32Pharmacokinetic model-predicted anticancer drug concentrations in human tumors. ( Bookman, MA; Gallo, JM; Guo, P; Li, S; Ma, J; Orlansky, A; Pulfer, S; Vicini, P; Zhou, F, 2004)
"Glioblastoma is the deadliest and most prevalent brain tumor."1.32Dexamethasone protected human glioblastoma U87MG cells from temozolomide induced apoptosis by maintaining Bax:Bcl-2 ratio and preventing proteolytic activities. ( Banik, NL; Das, A; Patel, SJ; Ray, SK, 2004)
"Temozolomide was administered p."1.31Biochemical correlates of temozolomide sensitivity in pediatric solid tumor xenograft models. ( Brent, TP; Friedman, HS; Houghton, PJ; Kirstein, MN; Middlemas, DS; Poquette, C; Stewart, CF, 2000)
"Temozolomide has recently been introduced by Schering-Plough Ltd (Welwyn Garden City, UK) as a new treatment which merits further investigation in this situation."1.31Temozolomide (Temodal) for treatment of primary brain tumours. ( MacConnachie, AM, 2000)
"Temozolomide was studied using a continuous exposure at final concentrations from 0."1.30Activity of temozolomide against human tumor colony-forming units. ( Dugan, M; Gerson, SL; Izbicka, E; Raymond, E; Soda, H; Von Hoff, DD, 1997)
"Thirty-three patients with newly diagnosed glioblastoma multiforme (GBM) and five patients with newly diagnosed anaplastic astrocytoma (AA) were treated with Temodal at a starting dose of 200 mg/m2 daily for 5 consecutive days with repeat dosing every 28 days after the first daily dose."1.30DNA mismatch repair and O6-alkylguanine-DNA alkyltransferase analysis and response to Temodal in newly diagnosed malignant glioma. ( Ashley, DM; Bigner, DD; Bigner, SH; Cokgor, I; Colvin, OM; Dugan, M; Friedman, AH; Friedman, HS; Haglund, MM; Henry, AJ; Kerby, T; Krischer, J; Lovell, S; Marchev, F; McLendon, RE; Modrich, PL; Provenzale, JM; Rasheed, K; Rich, J; Seman, AJ; Stewart, E, 1998)
"Temozolomide was also highly effective against intracerebral implants of the U251 and SF-295 glioblastomas."1.29Preclinical antitumor activity of temozolomide in mice: efficacy against human brain tumor xenografts and synergism with 1,3-bis(2-chloroethyl)-1-nitrosourea. ( Grever, MR; Koutsoukos, AD; Moore, TD; Plowman, J; Rubinstein, LV; Waud, WR, 1994)

Research

Studies (3,270)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's21 (0.64)18.2507
2000's606 (18.53)29.6817
2010's1793 (54.83)24.3611
2020's850 (25.99)2.80

Authors

AuthorsStudies
Clarion, L1
Jacquard, C1
Sainte-Catherine, O1
Loiseau, S1
Filippini, D1
Hirlemann, MH1
Volle, JN1
Virieux, D1
Lecouvey, M1
Pirat, JL1
Bakalara, N1
Liu, Z19
Yao, Y4
Kogiso, M1
Zheng, B1
Deng, L4
Qiu, JJ1
Dong, S4
Lv, H2
Gallo, JM9
Li, XN3
Song, Y8
de Moura Sperotto, ND1
Deves Roth, C1
Rodrigues-Junior, VS1
Ev Neves, C1
Reisdorfer Paula, F1
da Silva Dadda, A1
Bergo, P1
Freitas de Freitas, T1
Souza Macchi, F1
Moura, S1
Duarte de Souza, AP1
Campos, MM1
Valim Bizarro, C1
Santos, DS1
Basso, LA1
Machado, P1
Mujumdar, P2
Kopecka, J3
Bua, S1
Supuran, CT1
Riganti, C4
Poulsen, SA2
Braga, C2
Vaz, AR1
Oliveira, MC1
Matilde Marques, M1
Moreira, R2
Brites, D2
Perry, MJ2
Choi, PJ3
Cooper, E3
Schweder, P3
Mee, E3
Faull, R3
Denny, WA3
Dragunow, M3
Park, TI2
Jose, J3
Turner, C2
Dai, Z2
Liu, H15
Wang, B10
Yang, D3
Zhu, YY1
Yan, H8
Zhu, PF1
Liu, YP1
Chen, HC1
Zhao, YL1
Zhao, LX1
Zhao, XD1
Liu, HY1
Luo, XD1
Xiang, W5
Quadery, TM1
Hamel, E1
Luckett-Chastain, LR1
Ihnat, MA1
Mooberry, SL1
Gangjee, A2
Nguyen, P3
Doan, P3
Rimpilainen, T2
Konda Mani, S1
Murugesan, A3
Yli-Harja, O5
Candeias, NR3
Kandhavelu, M3
Yuan, P1
Gu, X3
Ni, X2
Qi, Y4
Shao, X1
Xu, X7
Liu, J22
Qian, X5
Gerlach, SL1
Dunlop, RA1
Metcalf, JS1
Banack, SA1
Cox, PA1
Delello Di Filippo, L1
Hofstätter Azambuja, J1
Paes Dutra, JA1
Tavares Luiz, M1
Lobato Duarte, J1
Nicoleti, LR1
Olalla Saad, ST1
Chorilli, M2
Li, J42
Sun, Y16
Sun, X8
Zhao, X3
Ma, Y5
Wang, Y66
Zhang, X35
Brandner, S4
McAleenan, A2
Kelly, C2
Spiga, F2
Cheng, HY2
Dawson, S2
Schmidt, L2
Faulkner, CL2
Wragg, C2
Jefferies, S3
Higgins, JPT2
Kurian, KM3
Tresch, NS1
Fuchs, D2
Morandi, L3
Tonon, C2
Rohrer Bley, C1
Nytko, KJ1
Lukas, RV6
Razis, ED1
Huse, JT5
Gondi, V5
Yamamuro, S2
Takahashi, M9
Satomi, K4
Sasaki, N2
Kobayashi, T2
Uchida, E2
Kawauchi, D3
Nakano, T2
Fujii, T2
Narita, Y21
Kondo, A1
Wada, K3
Yoshino, A6
Ichimura, K13
Tomiyama, A3
Li, C19
Li, W17
Dai, S2
Sharma, A4
Sharma, HS2
Wu, Y12
Brault, C1
Zerbib, Y1
Chouaki, T1
Maizel, J1
Nyga, R1
Li, F7
Chen, S12
Yu, J7
Gao, Z7
Sun, Z4
Yi, Y1
Long, T1
Zhang, C13
Li, Y50
Pan, Y5
Qin, C2
Long, W2
Liu, Q15
Zhao, W8
Muragaki, Y9
Kagawa, N5
Asai, K1
Nagane, M7
Matsuda, M4
Ueki, K2
Kuroda, J2
Date, I2
Kobayashi, H5
Kumabe, T7
Beppu, T4
Kanamori, M7
Kasai, S1
Nishimura, Y1
Xiong, H4
Ocampo, C1
Yamada, M1
Mishima, K3
Stockslager, MA1
Malinowski, S2
Touat, M4
Yoon, JC1
Geduldig, J1
Mirza, M1
Kim, AS1
Wen, PY37
Chow, KH3
Ligon, KL17
Manalis, SR1
Wang, Z30
Yang, Z7
Jiang, J9
Shi, Z9
Mao, Y2
Qin, N1
Tao, TH1
Jin, L3
Kiang, KM4
Cheng, SY3
Leung, GK10
Chuang, HY2
Hsu, LY1
Pan, CM1
Pikatan, NW1
Yadav, VK2
Fong, IH3
Chen, CH2
Yeh, CT4
Chiu, SC2
Larrouquère, L1
Berthier, S1
Chovelon, B1
Garrel, C1
Vacchina, V1
Paucot, H1
Boutonnat, J1
Faure, P1
Hazane-Puch, F1
Lavogina, D1
Laasfeld, T1
Vardja, M1
Lust, H1
Jaal, J1
Wan, Z1
Gu, J6
Qian, J5
Zhu, J8
Wang, J54
Chen, H13
Luo, C4
Tong, S2
Wu, J19
Long, J1
Zhong, P1
Rotondo, R1
Ragucci, S1
Castaldo, S1
Oliva, MA4
Landi, N1
Pedone, PV1
Arcella, A11
Di Maro, A1
Urbantat, RM1
Jelgersma, C1
Brandenburg, S1
Nieminen-Kelhä, M1
Kremenetskaia, I3
Zollfrank, J1
Mueller, S3
Rubarth, K1
Koch, A4
Vajkoczy, P11
Acker, G1
Lamb, LS2
Pereboeva, L1
Youngblood, S1
Gillespie, GY7
Nabors, LB16
Markert, JM6
Dasgupta, A3
Langford, C2
Spencer, HT2
Han, J6
Qiu, M1
Su, L3
Wu, C6
Cheng, S2
Zhao, Z11
Li, D10
Wang, M20
Tao, W1
Du, S3
Chernov, AN2
Alaverdian, DA2
Glotov, OS1
Talabaev, MV1
Urazov, SP1
Shcherbak, SG1
Renieri, A1
Frullanti, E1
Shamova, O1
Awah, CU1
Winter, J1
Mazdoom, CM1
Ogunwobi, OO1
Liu, Y53
Bao, Q1
Chen, Z19
Yao, L4
Ci, Z1
Wei, X6
Sun, K5
Zhou, G5
Li, S32
Ma, W8
Tao, K1
Huang, B3
Yu, Z13
Liang, R1
Bi, J1
Khan, A1
Tang, J7
Armando, AM1
Wu, S7
Zhang, W26
Gimple, RC1
Reed, A1
Jing, H1
Koga, T2
Wong, IT1
Gu, Y1
Miki, S1
Yang, H9
Prager, B1
Curtis, EJ1
Wainwright, DA2
Furnari, FB2
Rich, JN12
Cloughesy, TF21
Kornblum, HI3
Quehenberger, O1
Rzhetsky, A1
Cravatt, BF1
Mischel, PS4
Ding, Y3
He, L7
Song, X6
Zheng, C1
Yu, S4
Zhou, K2
Jiang, T22
Huang, L5
Li, G19
Lan, Q6
Vaugier, L1
Ah-Thiane, L1
Aumont, M2
Jouglar, E2
Campone, M3
Colliard, C1
Doucet, L1
Frenel, JS4
Gourmelon, C1
Robert, M1
Martin, SA1
Riem, T1
Roualdes, V2
Campion, L1
Mervoyer, A1
Zampieri, LX1
Sboarina, M1
Cacace, A1
Grasso, D1
Thabault, L1
Hamelin, L1
Vazeille, T1
Dumon, E1
Rossignol, R1
Frédérick, R1
Sonveaux, E1
Lefranc, F12
Sonveaux, P1
Tabouret, E6
Kishwar Jafri, SK1
Bukhari, SS1
Shamim, MS1
Saran, F11
Welsh, L1
James, A1
McBain, C3
Gattamaneni, R1
Harris, F1
Pemberton, K1
Schaible, J1
Bender, S1
Cseh, A3
Brada, M15
Poon, MTC2
Bruce, M1
Simpson, JE1
Hannan, CJ1
Brennan, PM2
Fazzari, FGT1
Rose, F1
Pauls, M1
Guay, E1
Ibrahim, MFK1
Basulaiman, B1
Tu, M3
Hutton, B1
Nicholas, G2
Ng, TL2
Garcia, CR2
Myint, ZW1
Jayswal, R1
Wang, C15
Morgan, RM2
Butts, AR1
Weiss, HL1
Villano, JL14
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Frank, B1
Möhle, R1
Charnley, N1
West, CM1
Barnett, CM1
Bydder, GM1
Glaser, M2
Swindell, R1
Matthews, J2
Schwarzmaier, HJ1
Eickmeyer, F1
von Tempelhoff, W1
Fiedler, VU1
Niehoff, H1
Ulrich, SD1
Ulrich, F1
Taliansky-Aronov, A1
Ngo, L1
Nei, M1
Kim, MK1
Lee, TK1
Kang, JK1
Kim, MC1
Diezi, M1
Stempak, D1
Moghrabi, A1
Coppes, MJ1
Fernandez, CV1
Rivera, E1
Valero, V1
Francis, D1
Broglio, K1
Yin, G1
Hortobagyi, GN1
Buchholz, T1
Biemond-ter Stege, EM1
Graveland, WJ1
Mutter, N1
Glantz, MJ3
Chalmers, L2
Van Horn, A1
Sloan, AE1
Bonaldi, L2
Maruno, M1
Fujimaki, T1
Kochi, M1
Hori, T1
Polyzos, A1
Stavrinidis, I1
Frangia, K1
Markopoulos, C1
Papadopoulos, O1
Pectasides, D1
Mantzourani, M1
Middleton, M1
Vaiopoulos, G1
Loeser, S1
Blaschke, B2
Tan, TC1
Mabasa, VH1
Taylor, SC1
Niedzwiecki, D1
Hodgson, L1
Haluska, FG1
Schadendorf, D1
Ugurel, S1
Thoelke, A1
Egberts, F1
Kreissig, M1
Linse, R1
Vogt, T1
Tilgen, W1
Mohr, P1
Eoh, W1
Gioia, V1
Biscuola, M1
Kemper, EM1
Leenders, W1
Küsters, B1
Lyons, S1
Buckle, T1
Heerschap, A2
Beijnen, JH1
van Tellingen, O1
Siker, ML1
Boor, S1
Banna, GL1
Bettio, D1
Rodriguez Baena, R1
Aimar, E1
Gaetani, P1
Colombo, P1
Rognone, F1
Liu, TJ1
Peterson, P2
Stevens, QE1
Howes, G1
Dickerman, RD1
Nardone, EM1
Contreras Martínez, J1
Azcoaga Blasco, JM1
Delgado Rico, R1
Wals Zurita, A1
Villanueva Alvarez, A1
Rivas Sánchez, D1
Herruzo Cabrera, I1
Gasco, J1
Park, JA2
Joe, YA1
Zeltzman, M1
Parisi, MA1
Liguoro, D1
Piao, Y1
Larkin, JM1
Hughes, SA1
Beirne, DA1
Patel, PM1
Gibbens, IM1
Bate, SC1
Thomas, K1
Eisen, TG1
Gore, ME1
de Gast, GC1
Dalesio, O1
Ishii, N1
Iwasaki, Y1
Zhang, JP1
Shi, HL1
Yue, WY1
Mu, YG1
Everhard, S1
Thillet, J1
Taniguchi, T1
Pitini, V1
Baldari, S1
Altavilla, G1
Arrigo, C1
Naro, C1
Perniciaro, F1
Capasso, E1
Caserta, L1
Pradilla, G1
Legnani, F1
Caplan, J1
Nuthalapati, S1
Mineo, JF1
Bordron, A1
Baroncini, M1
Blond, S1
Dam-Hieu, P1
Sohn, HJ1
Marg, E1
Rudolph, R1
Rauch, M1
Rieckmann, P1
Schuth, J1
Koch, H1
Zaja, F1
Mazza, E2
Spina, M1
Ilariucci, F1
Corazzelli, G1
Manno, P1
Candela, M1
Abbadessa, A1
Stelitano, C1
Latte, G1
Kamen, BA1
Gallego, JM1
Barcia, JA1
Barcia-Mariño, C1
Fehlauer, F1
Muench, M1
Richter, E1
Allen, JC1
Phillips, PC1
Watral, MA1
Krauser, JM1
Mora, A1
Prada, F1
Borsa, S1
Martinelli-Boneschi, F1
Saladino, A1
Gaini, SM1
de la Fuente, BP1
Dalmau, J1
Greenberger, NJ1
Gigas, DC2
Rabkin, S1
Betensky, RA1
Romany, CA1
Reavie, LB1
Goldman, B1
Choong, NW1
Mauer, AM1
Hoffman, PC1
Rudin, CM1
Winegarden, JD1
Kozloff, M1
Wade, JL1
Sciortino, DF1
Szeto, L1
Vokes, EE1
Dellinger, CA1
O'Toole, L1
Khanduri, S2
Gerrard, GE1
Vajramani, GV1
Dambatta, S1
Walker, M1
Grundy, PL1
Fuentes, S1
Eudes, N1
Lancelot, S1
Amiel-Benouaich, A1
Gatta, G1
Vecht, C1
Pore, N1
Cerniglia, GJ1
Mick, R1
Bernhard, EJ1
Hahn, SM1
Gupta, AK1
Maity, A1
McConville, P1
Moody, JB1
Leopold, WR1
Kreger, AR1
Woolliscroft, MJ1
Powathil, G1
Kohandel, M1
Sivaloganathan, S1
Oza, A1
Milosevic, M1
Menon, H2
Gujral, S1
Diakite, F1
Renard, MA1
Iraqi, W1
Jordan, JT1
Hussain, SF2
DeAngulo, G1
Kudo, M1
Singhal, N1
Selva-Nayagam, S1
Brown, MP1
Ang, EL1
Lim, CC1
Chan, SP1
Ty, A1
Tsuno, T1
Katsumata, S1
Mizuno, M1
Fujita, M1
Osawa, H1
Nakahara, N1
Satoh, Y1
Inagaki, M1
Fiumani, A2
Falcone, C2
Filippini, G2
Khaw, SL1
Coleman, LT1
Downie, PA1
Heath, JA1
Kouvaris, JR1
Miliadou, A1
Kouloulias, VE1
Kolokouris, D1
Balafouta, MJ1
Papacharalampous, XN1
Vlahos, LJ1
Gerrard, G1
Majer, M1
Jensen, RL1
Watson, GA1
Leachman, SA1
Boucher, KM1
Samlowski, WE1
Tartarone, A1
Ardito, R1
Romano, C1
Kruh, GD1
Dancey, J1
Crott, R2
Cornelissen, SJ1
Vriezen, M1
Dekkers, MM1
Errami, A1
Sijben, A1
Nicholson, HS1
Kretschmar, CS1
Krailo, M1
Kadota, R1
Harris, MB1
Tedeschi-Blok, N1
Sato, J1
Reaman, GH1
Yin, LT1
Fu, YJ1
Xu, QL1
Liu, ZL1
Liang, AH1
Fan, XJ1
Xu, CG1
Ishii, D1
Hatano, H1
Takeuchi, H1
Shimato, S1
Fujii, M1
Sawrie, SM1
Guthrie, BL1
Spencer, SA1
Meredith, RF1
Cloud, GA1
Nojima, K1
Pyrko, P1
Lee, AS1
Galanopoulos, N1
Rawlani, V1
Veerapong, J1
Bickenbach, K1
Taylor, RE1
Hulsebos, TJ1
Wagner, J2
Bischof, M4
Wagner, F2
Pitt, M1
Anderson, R1
Dyer, M1
Mealing, S1
Clarkson, A1
McKenzie, CA1
Biggs, MT1
Little, NS1
Cook, RJ1
Messina, M1
Robinson, BG1
Wallace, D1
Danks, MK1
Boyett, JM1
Gagel, B1
Stanzel, S1
Asadpour, B1
Katsuki, H1
Metha, M1
Robins, IH1
Sijens, PE1
Heesters, MA1
van der Graaf, WT1
Potze, JH1
Irwan, R1
Meiners, LC1
Oudkerk, M1
Karakis, I1
McGeeney, B1
Demierre, MF1
Thiele, JJ1
Wolpowitz, D1
Bhawan, J1
Goel, A1
Crutcher, L1
Hassenbusch, SJ1
Schmittling, B1
Kunwar, S1
Shaffrey, M1
Parker, K1
Grahn, AY1
Sherman, JW1
Husain, SR1
Claes, A1
Maass, C1
Leenders, WP1
Lamers, LM1
Al, MJ1
Mittmann, N1
Jin Seung, S1
Uyl-de Groot, CA1
Johansson, M1
Bergström, P1
Bergenheim, AT1
Avutu, B1
Barker, FG1
Shono, T1
Kil, WJ1
Cerna, D1
Balmaceda, C1
Cheung, YK1
Alavi, J1
Sisti, M1
Fine, RL1
Filippone, F1
Rausch, R2
Zabel-du Bois, A1
Fathi, AR1
Novoa, E1
El-Koussy, M1
Solari, A1
da Fonseca, CO1
Nagel, J1
Futuro, D1
Quirico-Santos, T1
Gattass, CR1
Debeir, O1
Kunz-Schughart, L1
Baumgart, U1
Hirschmann, B1
Weimann, E1
Muhleisen, H1
Ruemmele, P1
Steinbrecher, A1
Reichle, A1
Bael, TE1
Peterson, BL1
Nakamura, O1
McGibbon, B1
Graham, C1
Mischel, P1
Bergsneider, M1
Pope, W1
Lagattuta, TF1
Egorin, MJ1
Salvado, AJ1
Wei-Tsao, DD1
Lin, SH1
Steckley, JL1
Mitchell, SB1
Tsai, JS1
Adam, M1
Nagy, M1
Katz, RL1
Choi, JD1
Powers, CJ1
Longtine, JA1
Weaver, S1
Laforme, A1
Folkman, J1
Kieran, M1
Benveniste, RJ1
Manzano, G1
Petito, CK1
Andreoli, A1
Leonardi, M1
Gujrati, M1
Scheithauer, BW1
Zambrano, SC1
Jost, SC1
Raghavan, R1
Cochran, EJ1
Stalpers, L1
Hof, H1
Oertel, S1
Salgaller, ML1
Oliver, PG1
Belenky, ML1
Timmerman, R1
Flom, L1
Plowman, J1
Waud, WR1
Koutsoukos, AD1
Rubinstein, LV1
Moore, TD1
Grever, MR1
McVie, JG1
O'Reilly, SM3
Glaser, MG3
Brampton, M1
Rice-Edwards, JM2
Illingworth, RD2
Richards, PG2
Kennard, C1
Colquhoun, IR1
Lewis, P3
Devineni, D1
Klein-Szanto, A1
Buzaid, AC1
Bower, M3
Evans, H3
Brampton, MH4
Colquhoun, I3
Wedge, SR2
Porteous, JK1
Marcus, K1
Bleehen, NM1
Begent, RJ1
Calvert, H2
Roddie, M1
Rustin, GJ1
Marzolini, C2
Gander, M3
Biollaz, J2
Izbicka, E1
Soda, H1
Gerson, SL1
Von Hoff, DD1
Kerby, T2
Bigner, SH1
Henry, AJ1
Krischer, J1
Lovell, S1
Rasheed, K1
Marchev, F1
Seman, AJ1
Cokgor, I1
Stewart, E1
Colvin, OM1
Haglund, MM1
Sankar, A1
Thomas, DG1
Darling, JL1
Decosterd, L1
Bonfanti, M1
Liénard, D1
Perey, L1
Colella, G1
Yarosh, D1
Belanich, M1
D'Incalci, M1
Miller, JL1
Albright, R1
O'Neill, AM1
Bruner, J3
Yue, N3
Judson, I1
Beale, P1
Moore, S1
Reidenberg, P1
Statkevich, P1
Batra, V1
Cutler, D1
Young, H1
Middlemas, DS1
Poquette, C1
Brent, TP2
Landoni, C1
Villa, E1
MacConnachie, AM1
van Rijn, J1
van der Valk, P1
Albright, RE1
Fredericks, R1
Spence, A1
Hohl, RJ1
Selker, RG1
Vick, NA1
Phillips, P1
Cheshire, PJ1
Richmond, LB1
Poquette, CA1
Hulette, C1
Kosmidis, P2
Samantas, E2
Papakostas, P1
Karabelis, A2
Bacoyiannis, C1
Skarlos, DV1
Pinna, G1
Dirix, LY1
Bravo-Marques, JM1
Rao, S1
Bosik, ME1
Honore, S1
Frenkel, EP1
Wick, JB1
Dinnes, J2
Cave, C2
Major, K1
Milne, R2
Harris, MT1
Lutterbach, J1
Liegibel, J1
Madlinger, A1
Frommhold, H1
Keime-Guibert, F1
Eskens, FA1
Biasco, G1
Pantaleo, MA1
Casadei, S1
Fels, C1
Droege, JW1
Schäfer, C1
Olson, JD1
Mack, M1
Rodavitch, A1
Boutros, DY1
Benjelloun, A1
Delavelle, J1
Lazeyras, F1
Khan, RB1
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Georgoulias, V1
Kalofonos, Ch1
Santi, M1
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Maillard, I1
Maeder, P1
Meuli, R1
Janzer, R1
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Miralbell, R1
Porchet, F1
Paul, MJ1
Summers, Y1
Calvert, AH1
Rustin, G1
Margolin, K1
Atkins, B1
Thompson, A1
Ernstoff, S1
Flaherty, L1
Clark, I1
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Pavelka, Z1

Clinical Trials (236)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Non-Randomized, Open-Label, Multi-Center Phase 1/2 Study Evaluating the Safety, Pharmacokinetics and Efficacy of ABT-414 in Japanese Subjects With Malignant Glioma[NCT02590263]Phase 1/Phase 253 participants (Actual)Interventional2015-08-24Completed
Phase I, Open Label Trial to Explore Safety of Combining BIBW 2992 and Radiotherapy With or Without Temozolomide in Newly Diagnosed GBM[NCT00977431]Phase 136 participants (Actual)Interventional2009-09-17Completed
A Prospective Study of Concurrent Chemoradiotherapy With Temozolomide Versus Radiation Therapy Alone in Patients With IDH Wild-type/TERT Promoter Mutation Grade II/III Gliomas[NCT02766270]Early Phase 130 participants (Anticipated)Interventional2016-09-26Recruiting
A Phase I Study of CAN008 Plus Concomitant Temozolomide During and After Radiation Therapy in Patients With Newly Diagnosed Glioblastoma Multiforme[NCT02853565]Phase 110 participants (Actual)Interventional2016-08-31Completed
Effect of rhIL-7-hyFc on Increasing Lymphocyte Counts in Patients With Newly Diagnosed Non-severe Lymphopenic Gliomas Following Radiation and Temzolomide[NCT03687957]Phase 1/Phase 270 participants (Anticipated)Interventional2019-01-04Recruiting
Phase III Trial on Concurrent and Adjuvant Temozolomide Chemotherapy in Non-1p/19q Deleted Anaplastic Glioma. The CATNON Intergroup Trial.[NCT00626990]Phase 3751 participants (Actual)Interventional2007-12-31Active, not recruiting
A Randomized Phase 3 Single Blind Study of Temozolomide Plus Radiation Therapy Combined With Nivolumab or Placebo in Newly Diagnosed Adult Subjects With MGMT-Methylated (Tumor O6-methylguanine DNA Methyltransferase) Glioblastoma[NCT02667587]Phase 3716 participants (Actual)Interventional2016-05-09Active, not recruiting
The Combination of Hypofractionated Stereotactic Radiotherapy and Chemoradiotherapy Using Intensity-Modulated Radiotherapy for Newly Diagnosed Glioblastoma Multiforme: A Prospective, Single-Center, Single-Arm Phase II Clinical Trial[NCT04547621]Phase 1/Phase 250 participants (Anticipated)Interventional2020-09-01Active, not recruiting
EF-32: Pivotal, Randomized, Open-Label Study of Optune® (Tumor Treating Fields, 200kHz) Concomitant With Radiation Therapy and Temozolomide for the Treatment of Newly Diagnosed Glioblastoma[NCT04471844]950 participants (Anticipated)Interventional2020-12-08Recruiting
SPARE-Scalp Preservation and Radiation Plus Alternating Electric Tumor Treatment Field (NovoTTF, Optune) for Patients With Glioblastoma: A Pilot Study[NCT03477110]Early Phase 130 participants (Actual)Interventional2018-05-04Active, not recruiting
A Phase III Clinical Trial Evaluating DCVax®-L, Autologous Dendritic Cells Pulsed With Tumor Lysate Antigen For The Treatment Of Glioblastoma Multiforme (GBM)[NCT00045968]Phase 3348 participants (Anticipated)Interventional2006-12-31Active, not recruiting
Phase I/II Study of T-DM1 Alone Versus T-DM1 and Metronomic Temozolomide in Secondary Prevention of HER2-Positive Breast Cancer Brain Metastases Following Stereotactic Radiosurgery[NCT03190967]Phase 1/Phase 212 participants (Actual)Interventional2018-04-18Terminated (stopped due to The phase II portion was never started as we could no longer get the drug from the manufacturer.)
A Phase II Open-Label, Randomized, Multi-Centre Comparative Study Of Bevacizumab-Based Therapy In Paediatric Patients With Newly Diagnosed Supratentorial, Infratentorial Cerebellar, or Peduncular High-Grade Glioma[NCT01390948]Phase 2124 participants (Actual)Interventional2011-10-18Completed
Secondary Prophylaxis Use of Romiplostim for the Prevention of Thrombocytopenia Induced by Temozolomide in Newly Diagnosed Glioblastoma Patients[NCT02227576]Phase 220 participants (Actual)Interventional2014-07-10Terminated (stopped due to Study halted for efficacy following the results of the interim analysis provided for in the protocol on 20 patients.)
INTELLANCE-2: ABT-414 Alone or ABT-414 Plus Temozolomide Versus Lomustine or Temozolomide for Recurrent Glioblastoma: A Randomized Phase 2 Study of the EORTC Brain Tumor Group[NCT02343406]Phase 2266 participants (Actual)Interventional2015-02-17Completed
A Phase I/II Study of ABT-888, An Oral Poly(ADP-ribose) Polymerase Inhibitor, and Concurrent Radiation Therapy, Followed by ABT-888 and Temozolomide, in Children With Newly Diagnosed Diffuse Pontine Gliomas (DIPG)[NCT01514201]Phase 1/Phase 266 participants (Actual)Interventional2012-02-01Completed
A Prospective, Multi-center Trial of NovoTTF-100A Together With Temozolomide Compared to Temozolomide Alone in Patients With Newly Diagnosed GBM.[NCT00916409]Phase 3700 participants (Anticipated)Interventional2009-06-30Completed
Temozolomid (One Week on/One Week Off) Versus Strahlentherapie in Der Primärtherapie Anaplastischer Astrozytome Und Glioblastome Bei älteren Patienten: Eine Randomisierte Phase III-Studie (Methvsalem)[NCT01502241]Phase 3412 participants (Actual)Interventional2005-01-31Completed
Phase 1b/2a Study Combining LY2157299 With Standard Temozolomide-based Radiochemotherapy in Patients With Newly Diagnosed Malignant Glioma[NCT01220271]Phase 1/Phase 275 participants (Actual)Interventional2011-04-30Completed
Clinical Trial Phase IIB Randomized, Multicenter, of Continuation or Non Continuation With 6 Cycles of Temozolomide After the First 6 Cycles of Standard First-line Treatment in Patients With Glioblastoma.[NCT02209948]Phase 2166 participants (Actual)Interventional2014-08-22Completed
A Randomized Phase 3 Open Label Study of Nivolumab Versus Bevacizumab and Multiple Phase 1 Safety Cohorts of Nivolumab or Nivolumab in Combination With Ipilimumab Across Different Lines of Glioblastoma[NCT02017717]Phase 3529 participants (Actual)Interventional2014-02-07Active, not recruiting
Research on Precise Immune Prevention and Treatment of Glioma Based on Multi-omics Sequencing Data[NCT04792437]120 participants (Anticipated)Observational2021-03-10Recruiting
A Randomized Phase III Study of Temozolomide and Short-Course Radiation Versus Short-Course Radiation Alone In The Treatment of Newly Diagnosed Glioblastoma Multiforme in Elderly Patients[NCT00482677]Phase 3562 participants (Actual)Interventional2007-11-14Completed
Phase III Trial of CCNU/Temozolomide (TMZ) Combination Therapy vs. Standard TMZ Therapy for Newly Diagnosed MGMT-methylated Glioblastoma Patients[NCT01149109]Phase 3141 participants (Actual)Interventional2010-10-31Completed
A Phase 2/3 Randomized, Open-Label Study of Toca 511, a Retroviral Replicating Vector, Combined With Toca FC Versus Standard of Care in Subjects Undergoing Planned Resection for Recurrent Glioblastoma or Anaplastic Astrocytoma[NCT02414165]Phase 2/Phase 3403 participants (Actual)Interventional2015-11-30Terminated (stopped due to Sponsor Decision)
Impact of the Platelet Level During Radiotherapy Associated With Temozolomide in Patients Treated for Glioblastoma[NCT02617745]Phase 2244 participants (Actual)Interventional2015-11-30Active, not recruiting
BrUOG 329: Onivyde (Nanoliposomal Irinotecan) and Metronomic Temozolomide for Patients With Recurrent Glioblastoma: A Phase IB/IIA Brown University Oncology Research Group Study[NCT03119064]Phase 1/Phase 212 participants (Actual)Interventional2017-11-30Terminated (stopped due to lack of response to study therapy)
A Two Part Study to Assess the Tolerability, Safety and Pharmacodynamics of Sativex in Combination With Dose-intense Temozolomide in Patients With Recurrent Glioblastoma[NCT01812603]Phase 1/Phase 26 participants (Actual)Interventional2013-09-30Completed
A Two Part Study to Assess the Tolerability, Safety and Pharmacodynamics of Sativex in Combination With Dose-intense Temozolomide in Patients With Recurrent Glioblastoma[NCT01812616]Phase 1/Phase 221 participants (Actual)Interventional2014-09-30Completed
Evaluating the Impact of 18F-DOPA-PET on Radiotherapy Planning for Newly Diagnosed Gliomas[NCT01991977]Phase 291 participants (Actual)Interventional2013-12-31Active, not recruiting
A Phase I/II Study of Zotiraciclib for Recurrent High-Grade Gliomas With Isocitrate Dehydrogenase 1 or 2 (IDH1 or IDH2) Mutations[NCT05588141]Phase 1/Phase 296 participants (Anticipated)Interventional2023-05-16Recruiting
A Phase I Open Label Safety Study to Evaluate the Pharmacokinetic Profile and Tolerance of Mibefradil Dose Finding in Subjects With Recurrent High-Grade Glioma Undergoing Standard, Repeated Temozolomide Treatment[NCT01480050]Phase 128 participants (Actual)Interventional2012-05-31Completed
11C-methionine in Diagnostics and Management of Glioblastoma Multiforme With Rapid Early Progression Patients Prior to Adjuvant Oncological Therapy (GlioMET)[NCT05608395]Phase 271 participants (Anticipated)Interventional2020-12-04Recruiting
The Use of TTFields for Newly Diagnosed GBM Patients in Germany in Routine Clinical Care - TIGER Study[NCT03258021]710 participants (Actual)Observational2017-08-31Active, not recruiting
Use of TTFields in Germany in Routine Clinical Care Study PROgram - Daily Activity, Sleep and Neurocognitive Functioning in Newly Diagnosed Glioblastoma Patients Study[NCT04717739]500 participants (Anticipated)Observational2021-12-30Recruiting
A Phase II Trial of Intensive Chemotherapy and Autotransplantation for Patients With Newly Diagnosed Anaplastic Oligodendroglioma[NCT00588523]Phase 260 participants (Actual)Interventional2002-09-30Completed
Phase II Trial of Pulse Dosing of Lapatinib in Combination With Temozolomide and Regional Radiation Therapy for Upfront Treatment of Patients With Newly-Diagnosed Glioblastoma Multiforme[NCT01591577]Phase 250 participants (Actual)Interventional2012-12-07Active, not recruiting
Nitroglycerin Plus Whole Intracranial Radiotherapy for Brain Metastases in Non-small Cell Lung Cancer Patients: a Phase II Open Randomized Clinical Trial[NCT04338867]Phase 296 participants (Actual)Interventional2020-03-01Completed
Doxycycline Injection of Cutaneous Schwannoma in Neurofibromatosis Type 2[NCT05521048]Phase 1/Phase 219 participants (Anticipated)Interventional2022-09-19Recruiting
An International, Randomized, Double-Blind, Controlled Study of Rindopepimut/GM-CSF With Adjuvant Temozolomide in Patients With Newly Diagnosed, Surgically Resected, EGFRvIII-positive Glioblastoma[NCT01480479]Phase 3745 participants (Actual)Interventional2011-11-30Completed
A Randomized, Placebo Controlled Phase 3 Study of ABT-414 With Concurrent Chemoradiation and Adjuvant Temozolomide in Subjects With Newly Diagnosed Glioblastoma (GBM) With Epidermal Growth Factor Receptor (EGFR) Amplification (Intellance1)[NCT02573324]Phase 3691 participants (Actual)Interventional2015-01-04Completed
[NCT00967330]Phase 2182 participants (Actual)Interventional2010-06-30Completed
Phase I/II Trial of Concurrent RAD001 (Everolimus) With Temozolomide/Radiation Followed by Adjuvant RAD001/Temozolomide in Newly Diagnosed Glioblastoma[NCT01062399]Phase 1/Phase 2279 participants (Actual)Interventional2010-12-31Completed
EF-36/Keynote B36: A Pilot, Randomized, Open-label Study of Tumor Treating Fields (TTFields, 150 kHz) Concomitant With Pembrolizumab for First Line Treatment of Advanced or Metastatic Non-small Cell Lung Cancer[NCT04892472]Phase 2100 participants (Anticipated)Interventional2021-07-12Recruiting
ENGOT-ov50 / GOG-3029 / INNOVATE-3: Pivotal, Randomized, Open-label Study of Tumor Treating Fields (TTFields, 200kHz) Concomitant With Weekly Paclitaxel for the Treatment of Recurrent Ovarian Cancer[NCT03940196]Phase 3540 participants (Actual)Interventional2019-03-22Active, not recruiting
EF-33: An Open-Label Pilot Study of OPTUNE® (TTFields, 200 Khz) With High Density Transducer Arrays for the Treatment of Recurrent Glioblastoma[NCT04492163]Phase 225 participants (Anticipated)Interventional2020-07-14Recruiting
A Phase 2, Single Arm, Multi-center, Open-Label Trial to Evaluate the Safety and Efficacy of Treatment With Tumor Treating Fields (TTFields) and Chemotherapy as First-Line Treatment for Subjects With Unresectable Gastroesophageal Junction (GEJ) Adenocarci[NCT04281576]28 participants (Anticipated)Interventional2019-12-19Recruiting
Phase III Intergroup Study of Radiotherapy With Concomitant and Adjuvant Temozolomide Versus Radiotherapy With Adjuvant PCV Chemotherapy in Patients With 1p/19q Co-deleted Anaplastic Glioma or Low Grade Glioma[NCT00887146]Phase 3360 participants (Anticipated)Interventional2009-09-30Recruiting
Primary Chemotherapy With Temozolomide Versus Radiotherapy in Patients With Low Grade Gliomas After Stratification for Genetic 1p Loss: A Phase III Study[NCT00182819]Phase 3709 participants (Actual)Interventional2005-07-31Completed
A Phase II Study of a Temozolomide-Based Chemoradiotherapy Regimen for High-Risk Low-Grade Gliomas[NCT00114140]Phase 2136 participants (Actual)Interventional2005-01-31Completed
A Phase 1 Study Evaluating the Safety and Pharmacokinetics of ABT-414 for Subjects With Glioblastoma Multiforme[NCT01800695]Phase 1202 participants (Actual)Interventional2013-04-02Completed
Randomized Trial Assessing the Significance of Bevacizumab in Recurrent Grade II and Grade III Gliomas - The TAVAREC Trial[NCT01164189]Phase 2155 participants (Actual)Interventional2011-02-28Completed
Safety of Intensity-modulated Radiotherapy Treatment With Inhomogeneous Dose Distribution in Patients With Relapsed High-grade Gliomas.[NCT04610229]12 participants (Actual)Interventional2016-02-01Completed
An Open Label, Prospective, Pilot Study to Evaluate the Efficacy and Safety of Best Physician's Choice of Standard of Care Combined With NaviFUS System in Patients With Recurrent Glioblastoma Multiforme[NCT04446416]6 participants (Actual)Interventional2020-07-21Completed
A Study to Evaluate the Safety and Feasibility of Blood-Brain Barrier Disruption Using Transcranial MRI-Guided Focused Ultrasound With Intravenous Ultrasound Contrast Agents in the Treatment of Brain Tumours With Doxorubicin[NCT02343991]10 participants (Anticipated)Interventional2014-10-31Active, not recruiting
A Phase II, Multicenter, Open-Label, Single-Arm Study to Evaluate the Safety, Tolerability, and Efficacy of DIsulfiram and Copper Gluconate in Recurrent Glioblastoma[NCT03034135]Phase 223 participants (Actual)Interventional2017-03-09Completed
Phase III Randomized Study Comparing 2 Brain Conformational Radiotherapy in Combination With Chemotherapy in the Treatment of Glioblastoma : Standard 3D Conformational Radiotherapy Versus Intensity-modulated Radiotherapy With Simultaneous-integrated Boost[NCT01507506]Phase 3180 participants (Actual)Interventional2011-03-15Terminated
Ependymomics: Multiomic Approach to Radioresistance of Ependymomas in Children and Adolescents[NCT05151718]370 participants (Anticipated)Observational2021-09-30Recruiting
Evaluation of ex Vivo Drug Combination Optimization Platform in Recurrent High Grade Astrocytic Glioma[NCT05532397]10 participants (Anticipated)Interventional2023-02-17Recruiting
Phase I/IIa Study of Concomitant Radiotherapy With Olaparib and Temozolomide in Unresectable High Grade Gliomas Patients[NCT03212742]Phase 1/Phase 291 participants (Anticipated)Interventional2017-09-04Recruiting
Fractionated Stereotactic Radiotherapy Combined With Temozolomide for Refractory Brain Metastases: A Single-arm, Single-center Phase II Trial[NCT02654106]Phase 265 participants (Actual)Interventional2011-10-31Completed
A FIH Feasibility Study to Evaluate the Safety of Transient Disruption of Blood-brain Barrier in Recurrent Glioblastoma Multiforme (GBM) Patients Using NaviFUS System[NCT03626896]6 participants (Actual)Interventional2018-08-17Completed
Phase I Study of Subventricular Zone Tumor Stem Cell Stereotactic Radiosurgery With Standard of Care Chemoradiation Therapy in Newly Diagnosed Malignant Gliomas (WHO III and WHO IV Astrocytomas)[NCT03956706]0 participants (Actual)Interventional2018-12-24Withdrawn (stopped due to no partipants enrolled and investigator left the institution)
A Phase I Study of SAHA and Temozolomide in Children With Relapsed or Refractory Primary Brain or Spinal Cord Tumors[NCT01076530]Phase 127 participants (Actual)Interventional2010-02-28Completed
Temozolomide Plus Bevacizumab Chemotherapy in Supratentorial Glioblastoma in 70 Years and Older Patients With an Impaired Functional Status (KPS<70)[NCT02898012]Phase 270 participants (Actual)Interventional2010-10-31Completed
The Prospective Trial for Validation of the Role of Levetiracetam as a Sensitizer of Temozolomide in the Treatment of Newly Diagnosed Glioblastoma Patients[NCT02815410]Phase 273 participants (Anticipated)Interventional2016-07-31Not yet recruiting
Characterization of 18F-Fluciclovine PET Amino Acid Radiotracer in Resected Brain Metastasis[NCT05554302]Phase 220 participants (Anticipated)Interventional2023-01-10Recruiting
A Modified Ketogenic, Anti-Inflammatory Diet for Patients With High-Grade Gliomas[NCT05373381]10 participants (Anticipated)Interventional2022-05-18Recruiting
Neural Stem Cell Oncolytic Adenoviral Virotherapy of Newly Diagnosed Malignant Glioma[NCT03072134]Phase 112 participants (Actual)Interventional2017-04-24Completed
Glioblastoma Multiforme Patients in Clinical Trials: An Examination of Their Clinical Trial Experiences[NCT05958485]500 participants (Anticipated)Observational2024-08-31Not yet recruiting
Phase III Trial Comparing Conventional Adjuvant Temozolomide With Dose-Intensive Temozolomide in Patients With Newly Diagnosed Glioblastoma[NCT00304031]Phase 31,173 participants (Actual)Interventional2006-01-31Completed
An Open Label Phase 1b/2 Study of Orally Administered PLX3397 in Combination With Radiation Therapy and Temozolomide in Patients With Newly Diagnosed Glioblastoma[NCT01790503]Phase 1/Phase 265 participants (Actual)Interventional2013-07-18Completed
Integration of Neurocognitive Biomarkers Into a Neuro-Oncology Clinic[NCT05504681]200 participants (Anticipated)Observational2021-11-03Recruiting
Validity and Reliability Evaluation of the Patient-Reported Outcomes Version of the Common Terminology Criteria for Adverse Events (PRO-CTCAE) for Adult-type Diffuse Gliomas Patients in Chinese Population[NCT05486923]450 participants (Anticipated)Observational2022-09-19Recruiting
A Phase Ib/II Study of AZD2171 in Combination With Daily Temozolomide and Radiation in Patients With Newly Diagnosed Glioblastoma Not Taking Enzyme-Inducing Anti-epileptic Drugs[NCT00662506]Phase 1/Phase 246 participants (Actual)Interventional2008-04-30Completed
Quantitative Assessment of the Early and Late Effects of Radiation and Chemotherapy on Glioblastoma Using Multiple MRI Techniques[NCT00756106]15 participants (Actual)Interventional2008-07-31Terminated (stopped due to Funding ended)
A Phase I Trial of Hypofraction Radiotherapy + Temozolomide in the Treatment of Patients With Glioblastoma Multiforme and Anaplastic Astrocytoma of the Brain[NCT00841555]Phase 19 participants (Actual)Interventional2009-02-13Completed
A Randomized, Double-Blind, Placebo-Controlled, Multicenter Phase III Trial of Bevacizumab, Temozolomide and Radiotherapy, Followed by Bevacizumab and Temozolomide Versus Placebo, Temozolomide and Radiotherapy Followed by Placebo and Temozolomide in Patie[NCT00943826]Phase 3921 participants (Actual)Interventional2009-06-29Completed
Precoce Medical Care by the Mobil Support for Patients With Glioblastoma Receiving Specific Medical Oncology Treatment[NCT04516733]35 participants (Actual)Interventional2019-05-10Completed
Phase III Double-blind Placebo-Controlled Trial of Conventional Concurrent Chemoradiation and Adjuvant Temozolomide Plus Bevacizumab Versus Conventional Concurrent Chemoradiation and Adjuvant Temozolomide in Patients With Newly Diagnosed Glioblastoma[NCT00884741]Phase 3637 participants (Actual)Interventional2009-04-15Completed
Pre-operative Radiation Therapy (RT) and Temozolomide (TMZ) in Patients With Newly Diagnosed Glioblastoma. A Phase I Study. (PARADIGMA)[NCT03480867]Phase 10 participants (Actual)Interventional2017-03-31Withdrawn (stopped due to competing study was opened by the surgeon after this trial was opened)
A Phase II Study of Bevacizumab Plus Temodar and Tarceva After Radiation Therapy and Temodar in Patients With Newly Diagnosed Glioblastoma or Gliosarcoma Who Are Stable Following Radiation[NCT00525525]Phase 274 participants (Actual)Interventional2007-09-30Completed
Phase II Study of 7 Days On/7 Days Off Temozolomide in Patients With High-Grade Glioma[NCT00619112]Phase 260 participants (Actual)Interventional2007-10-31Completed
Evaluation of the Irinotecan/Bevacizumab Association as Neo-adjuvant and Adjuvant Treatment of Chemoradiation With Temozolomide for Naive Unresectable Glioblastoma. Phase II Randomized Study With Comparison to Chemoradiation With Temozolomide[NCT01022918]Phase 2134 participants (Actual)Interventional2009-01-31Completed
Phase I Dose Finding Study of Sorafenib in Combination With Radiation Therapy and Temozolomide as a First Line Treatment of Patients With High Grade Glioma[NCT00884416]Phase 117 participants (Actual)Interventional2009-03-31Completed
A Phase I/II Trial of Hydroxychloroquine in Conjunction With Radiation Therapy and Concurrent and Adjuvant Temozolomide in Patients With Newly Diagnosed Glioblastoma Multiforme[NCT00486603]Phase 1/Phase 292 participants (Actual)Interventional2007-10-29Completed
A Randomized Phase 2 Study of Maintenance Temozolomide Versus Observation in Stable or Responding Stage III/IV Non-Small Cell Lung Cancer Patients[NCT00632203]Phase 253 participants (Actual)Interventional2008-03-04Terminated
Benzylguanine-Mediated Tumor Sensitization With Chemoprotected Autologous Stem Cells for Patients With Malignant Gliomas[NCT00669669]Phase 1/Phase 212 participants (Actual)Interventional2009-02-25Terminated (stopped due to Terminated due to loss in funding.)
Cilengitide for Subjects With Newly Diagnosed Glioblastoma and Methylated MGMT Gene Promoter - A Multicenter, Open-label, Controlled Phase III Study, Testing Cilengitide in Combination With Standard Treatment (Temozolomide With Concomitant Radiation Thera[NCT00689221]Phase 3545 participants (Actual)Interventional2008-09-30Completed
A Randomized, Factorial-Design, Phase II Trial of Temozolomide Alone and in Combination With Possible Permutations of Thalidomide, Isotretinoin and/or Celecoxib as Post-Radiation Adjuvant Therapy of Glioblastoma Multiforme[NCT00112502]Phase 2178 participants (Actual)Interventional2005-09-30Completed
Phase II Randomized Multicenter Study Comparing Brain Radiation in Combination With Temozolomide or Radiation Alone in Patients With Brain Metastases From Breast Cancer[NCT00875355]Phase 2100 participants (Anticipated)Interventional2007-11-30Recruiting
A Phase II Study of Cabozantinib for Patients With Recurrent or Progressive Meningioma[NCT05425004]Phase 224 participants (Anticipated)Interventional2022-05-27Recruiting
A Phase II Study of CDX-110 With Radiation and Temozolomide in Patients With Newly Diagnosed Glioblastoma Multiforme[NCT00458601]Phase 282 participants (Actual)Interventional2007-08-31Completed
Prospective Observational Study of Imaging-based Response Prediction for Anti-angiogenic Treatment in Recurrent Glioblastomas[NCT04143425]50 participants (Anticipated)Observational2020-02-06Recruiting
An Italian Multicenter Phase II Trial of Metronomic Temozolomide in Unfit Patients With Advanced Neuroendocrine Neoplasms (NENs): MeTe Study[NCT05554003]Phase 246 participants (Anticipated)Interventional2022-01-14Recruiting
Phase 1/2 Open Single-arm Monocentric Study Evaluating the Tolerance and Interest of Transient Opening of the Blood-Brain Barrier by Low Intensity Pulsed Ultrasound With the SONOCLOUD® Implantable Medical Device in Mild Alzheimer's Disease Patients (MMSE [NCT03119961]Phase 1/Phase 210 participants (Actual)Interventional2017-06-26Completed
A PHASE I/II TRIAL OF TEMOZOLOMIDE, MOTEXAFIN GADOLINIUM, AND 60 GY FRACTIONATED RADIATION FOR NEWLY DIAGNOSED SUPRATENTORIAL GLIOBLASTOMA MULTIFORME[NCT00305864]Phase 1/Phase 2118 participants (Actual)Interventional2006-02-09Completed
A Prospective Phase II Study in Patients With Mucosal Melanoma of Head and Neck in Intensity-modulated Radiotherapy Era[NCT03138642]Phase 230 participants (Anticipated)Interventional2010-07-01Recruiting
Improvement of Functional Outcome for Patients With Newly Diagnosed Grade II or III Glioma With Co-deletion of 1p/19q - IMPROVE CODEL: the NOA-18 Trial[NCT05331521]Phase 3406 participants (Anticipated)Interventional2021-04-07Recruiting
Avastin in Combination With Temozolomide and Irinotecan for Unresectable or Multifocal Glioblastoma Multiformes and Gliosarcomas[NCT00979017]Phase 241 participants (Actual)Interventional2009-11-30Completed
NIVOLUMAB Plus IPILIMUMAB and TEMOZOLOMIDE in Combination in Microsatellite Stable (MSS), MGMT Silenced Metastatic Colorectal Cancer (mCRC): the MAYA Study[NCT03832621]Phase 2135 participants (Actual)Interventional2019-03-25Completed
Multicenter Phase II Study of Preoperative Chemoradiotherapy With CApecitabine Plus Temozolomide in Patients With MGMT Silenced and Microsatellite Stable Locally Advanced RecTal Cancer: the CATARTIC Trial[NCT05136326]Phase 221 participants (Anticipated)Interventional2021-12-01Recruiting
Pembrolizumab in MMR-Proficient Metastatic Colorectal Cancer Pharmacologically Primed to Trigger Dynamic Hypermutation Status[NCT03519412]Phase 2102 participants (Anticipated)Interventional2019-01-23Active, not recruiting
An Open-label, Single-arm, Phase II Study to Evaluate Safety and Efficacy of Doxorubicin in Combination With Radiotherapy, Temozolomide and Valproic Acid in Patients With Glioblastoma Multiforme (GBM) and Diffuse Intrinsic Pontine Glioma (DIPG)[NCT02758366]Phase 221 participants (Actual)Interventional2016-02-29Terminated (stopped due to Study was terminated due to high heterogeneity of enrolled patients)
A Randomized, Double-Blind, Placebo-Controlled, Phase 2 Study Evaluating the Efficacy of ABT-888 in Combination With Temozolomide Versus Temozolomide Alone in Subjects With Metastatic Melanoma[NCT00804908]Phase 2346 participants (Actual)Interventional2009-02-28Completed
Restrictive Use of Dexamethasone in Glioblastoma[NCT04266977]50 participants (Anticipated)Interventional2020-05-08Recruiting
Pivotal, Randomized, Open-label Study of Tumor Treating Fields (TTFields, 150kHz) Concomitant With Gemcitabine and Nab-paclitaxel for Front-line Treatment of Locally-advanced Pancreatic Adenocarcinoma[NCT03377491]Phase 3556 participants (Anticipated)Interventional2018-02-10Active, not recruiting
HUMC 1612: A Phase I Trial of the Optune NovoTTF-200A System With Concomitant Temozolomide and Bevacizumab in Pediatric Patients With High-grade Glioma[NCT03128047]Phase 16 participants (Actual)Interventional2017-04-06Active, not recruiting
HEPANOVA: A Phase II Trial of Tumor Treating Fields (TTFields, 150kHz) Concomitant With Sorafenib For Advanced Hepatocellular Carcinoma (HCC)[NCT03606590]Phase 225 participants (Actual)Interventional2019-02-15Active, not recruiting
Pivotal, Open-label, Randomized Study of Radiosurgery With or Without Tumor Treating Fields (TTFields) for 1-10 Brain Metastases From Non-small Cell Lung Cancer (NSCLC).[NCT02831959]Phase 3270 participants (Anticipated)Interventional2016-07-31Active, not recruiting
LUNAR: Pivotal, Randomized, Open-label Study of Tumor Treating Fields (TTFields) Concurrent With Standard of Care Therapies for Treatment of Stage 4 Non-small Cell Lung Cancer (NSCLC) Following Platinum Failure[NCT02973789]Phase 3276 participants (Actual)Interventional2016-12-31Active, not recruiting
EPIBRAINRAD : Study of Neurological Complication After Radiotherapy for Glioblastoma High Grade[NCT02544178]200 participants (Anticipated)Observational2015-04-30Recruiting
Simultaneous Integrated Boost FDOPA PET Guided in Patients With Partially- or Non-operated Glioblastoma[NCT05653622]Phase 275 participants (Anticipated)Interventional2023-03-01Not yet recruiting
Evaluation of 18F-Fluciclovine PET-MRI to Differentiate Tumor Progression From Post-treatment Changes in Pediatric High-grade Glioma (HGG)[NCT05553041]Early Phase 130 participants (Anticipated)Interventional2023-08-07Recruiting
[NCT01702610]50 participants (Actual)Interventional2008-12-31Completed
The Efficacy and Safety of Temozolomide in Patients With Relapsed or Advanced Anaplastic Oligodendroglioma and Oligoastrocytoma: a Multicenter, Single-arm, Phase II Trial[NCT01847235]Phase 223 participants (Actual)Interventional2013-05-31Completed
A Phase II Trial Of Pre-Irradiation And Concurrent Temozolomide In Patients With Newly Diagnosed Anaplastic Oligodendrogliomas And Mixed Anaplastic Oligoastrocytomas[NCT00033280]Phase 242 participants (Actual)Interventional2002-07-31Completed
A PHASE III TRIAL COMPARING THE USE OF RADIOSURGERY FOLLOWED BY CONVENTIONAL RADIOTHERAPY WITH BCNU TO CONVENTIONAL RADIOTHERAPY WITH BCNU FOR SUPRATENTORIAL GLIOBLASTOMA MULTIFORME[NCT00002545]Phase 3200 participants (Anticipated)Interventional1994-02-28Completed
Phase II Study of Tarceva Plus Temodar During and Following Radiation Therapy in Patients With Newly Diagnosed Glioblastoma Multiforme and Gliosarcoma[NCT00187486]Phase 266 participants (Actual)Interventional2004-08-31Completed
Randomized Phase II of TARCEVA™ (Erlotinib) Versus Temozolomide Or BCNU in Patients With Recurrent Glioblastoma Multiforme[NCT00086879]Phase 2110 participants (Actual)Interventional2004-05-31Completed
Concomitant and Adjuvant Temozolomide and Radiotherapy for Newly Diagnosed Glioblastoma Multiforme - A Randomized Phase III Study[NCT00006353]Phase 3575 participants (Actual)Interventional2000-07-31Completed
Spatial Analysis and Validation of Glioblastoma on 7 T MRI[NCT02062372]5 participants (Actual)Interventional2014-12-10Terminated (stopped due to Expectation that within the set time period insufficient patients will be included, so endpoints will not be achieved)
Pilot Study of Concomitant NovoTTF-200A and Temozolomide Chemoradiation for Newly Diagnosed Glioblastoma[NCT03232424]Phase 112 participants (Actual)Interventional2017-07-26Completed
Metformin and Neo-adjuvant Temozolomide and Hypofractionated Accelerated Limited-margin Radiotherapy Followed by Adjuvant Temozolomide in Patients With Glioblastoma Multiforme (M-HARTT STUDY)[NCT02780024]Phase 250 participants (Anticipated)Interventional2015-03-31Active, not recruiting
Use of PET/CT Imaging With 18F-fluoroethylcholine (FEC) in the Evaluation of Patients Treated With Radiotherapy and Temozolomide Following a Diagnosis of Glioblastoma Multiforme[NCT00943462]0 participants (Actual)Observational2009-06-30Withdrawn (stopped due to No eligible patients could be recruited.)
Demeclocycline Fluorescence for Intraoperative Delineation Brain Tumors[NCT02740933]Phase 140 participants (Anticipated)Interventional2016-04-30Not yet recruiting
Phase II Clinical Trial on the Combination of Avelumab and Axitinib for the Treatment of Patients With Recurrent Glioblastoma[NCT03291314]Phase 252 participants (Actual)Interventional2017-05-03Completed
Retrospective Evaluation of Prognostic and/or Predictive Profile of Melanocortin Receptor-4 Gene Polymorphisms in Patient With a Diagnosis of Glioblastoma Treated With Upfront Concomitant Radio-chemotherapy or Chemotherapy[NCT02458508]65 participants (Actual)Observational2015-03-31Completed
Effect of stRess and exeRcize on the Outcome After Chemo-Radiation[NCT05431348]40 participants (Anticipated)Observational2022-06-01Recruiting
Prospective Randomized Phase II Trial of Hypofractionated Stereotactic Radiotherapy in Recurrent Glioblastoma Multiforme[NCT01464177]Phase 240 participants (Anticipated)Interventional2011-10-31Active, not recruiting
Phase I Trial of Temodar Plus O6-Benzylguanine (O6-BG) (NSC 637037) in the Treatment of Patients With Newly Diagnosed (Part 1) or Recurrent/Progressive (Parts 1 and 2) Cerebral Anaplastic Gliomas[NCT00006474]Phase 10 participants Interventional2001-03-31Completed
A Pilot Study of GRN1005 for Resectable Brain Metastases in Patients With Breast Cancer and Non-Small Cell Lung Cancer[NCT01679743]Phase 20 participants (Actual)Interventional2012-08-29Withdrawn
Multicenter Phase 2 Evaluation of Temozolomide for Treatment of Brain Metastases of Either Malignant Melanoma, Breast and Non-small Cell Lung Cancer.[NCT00831545]Phase 2162 participants (Actual)Interventional2000-12-01Completed
A Phase 2a Study of the Addition of Temozolomide to a Standard Conditioning Regimen for Autologous Stem Cell Transplantation in Relapsed and Refractory Central Nervous System (CNS) Lymphoma[NCT01235793]Phase 211 participants (Actual)Interventional2010-10-14Terminated (stopped due to The clinical trial was terminated due to poor enrollment)
Phase I/II Study on Concomitant and Adjuvant Temozolomide and Radiotherapy With or Without PTK787/ZK222584 in Newly Diagnosed GBM[NCT00128700]Phase 1/Phase 220 participants (Actual)Interventional2005-06-30Completed
A Systemic Temozolomide Treatment Of Melanoma Present In The Central Nervous System[NCT00068666]Phase 241 participants (Actual)Interventional2004-01-31Terminated
A Phase II Trial of Concurrent Sunitinib, Temozolomide and Radiation Therapy Followed by Adjuvant Temozolomide for Newly Diagnosed Glioblastoma Patients With an Unmethylated MGMT Gene Promoter[NCT02928575]Phase 245 participants (Anticipated)Interventional2012-08-31Recruiting
Phase II Study of Neoadjuvant Chemoradiation for Resectable Glioblastoma (NeoGlio)[NCT04209790]Phase 230 participants (Anticipated)Interventional2020-04-01Recruiting
The Temozolomide RESCUE Study: A Phase II Trial of Continuous (28/28) Dose-intense Temozolomide (CDIT) Chemotherapy After Progression on Conventional 5/28 Day Temozolomide in Patients With Recurrent Malignant Glioma[NCT00392171]Phase 2120 participants (Actual)Interventional2006-06-09Completed
A Phase II Study o the Adjuvant Use of Anti-Epidermal Growth Factor Receptor-425 (Anti-EGFR-425) Monoclonal Antibody Radiolabeled With I-125 for High Grade Gliomas[NCT00589706]Phase 211 participants (Actual)Interventional1985-01-31Completed
A Randomized, Open-Label Phase 2 Study of Temozolomide Added to Whole Brain Radiation Therapy Versus Whole Brain Radiation Therapy Alone for the Treatment of Brain Metastasis From Non-Small Cell Lung Cancer[NCT00076856]Phase 295 participants (Actual)Interventional2004-03-31Completed
Phase 2 Study of Sorafenib Plus Protracted Temozolomide in Recurrent Glioblastoma Multiforme[NCT00597493]Phase 232 participants (Actual)Interventional2007-09-30Completed
Phase II Study of Patients With Recurrent Glioblastoma Multiforme Treated With Maximal Safe Neurosurgical Resection and Intra-Operative Radiation Therapy (IORT) Using the Xoft Axxent Electronic Brachytherapy System and Bevacizumab[NCT04681677]Phase 2100 participants (Anticipated)Interventional2021-11-02Recruiting
A Pilot Study of Patients With Recurrent Glioblastoma Treated With Maximal Safe Neurosurgical Resection, Intra-Operative Radiation Therapy (IORT) Using the Xoft® Axxent® Electronic Brachytherapy System[NCT04763031]1 participants (Actual)Interventional2021-03-05Terminated (stopped due to No potential patients enrolled since first enrollment on 06/27/2022.)
A Phase II Trial of Concurrent Radiation Therapy and Temozolomide Followed by Temozolomide Plus Sorafenib in the First-Line Treatment of Patients With Glioblastoma Multiforme[NCT00544817]Phase 247 participants (Actual)Interventional2007-04-30Completed
Phase I Study of In Situ Autologous Vaccination Against Prostate Cancer With Intratumoral and Systemic Hiltonol® (Poly-ICLC) Prior To Radical Prostatectomy[NCT03262103]Phase 113 participants (Actual)Interventional2017-06-16Completed
A Phase II Trial of Radiation Plus Temozolomide Followed by Adjuvant Temozolomide and Poly-ICLC in Patients With Newly Diagnosed Glioblastoma Multiforme[NCT00262730]Phase 297 participants (Actual)Interventional2006-01-31Completed
A Phase I-Ib, Double-blinded, Randomized Repeated Dose Single Center, Safety and Immunogenicity Study of Nasal Poly-ICLC (Hiltonol®) in Healthy COVID-19 Vaccinated Adults[NCT04672291]Phase 143 participants (Actual)Interventional2021-07-21Completed
Direct Injection of Poly-ICLC (Hiltonol®) Vaccine In Malignant Pleural Mesothelioma[NCT04525859]Phase 119 participants (Anticipated)Interventional2020-08-19Recruiting
Treatment of Solid Tumors With Intratumoral Hiltonol® (Poly-ICLC): A Phase II Clinical Study[NCT01984892]Phase 28 participants (Actual)Interventional2013-11-30Terminated (stopped due to PI discretion, low enrollment)
Randomized Phase II Study Evaluating a Carbon Ion Boost Applied After Combined Radiochemotherapy With Temozolomide Versus a Proton Boost After Radiochemotherapy With Temozolomide in Patients With Primary Glioblastoma[NCT01165671]100 participants (Actual)Interventional2010-07-31Completed
A Phase I Study of PRK787/ZK 222584 in Combination With Daily Temozolomide and Radiation in Patients With Newly Diagnosed Glioblastoma[NCT00385853]Phase 119 participants (Actual)Interventional2006-09-30Completed
Phase I/II Evaluation of Everolimus (RAD001), Radiation and Temozolomide (TMZ) Followed by Adjuvant Temozolomide and Everolimus in Newly Diagnosed Glioblastoma[NCT00553150]Phase 1/Phase 2122 participants (Actual)Interventional2009-03-31Completed
A Complementary Trial of an Immunotherapy Vaccine Against Tumor-Specific EGFRvIII[NCT00643097]Phase 240 participants (Actual)Interventional2007-09-30Completed
A Prospective Cohort to Study the Effect of Postoperative Upfront Temozolomide Chemotherapy on IDH Mutational Low Grade Gliomas in Eloquent Areas[NCT02209428]Phase 254 participants (Actual)Interventional2014-06-30Active, not recruiting
A Phase I Dose Escalation Study of Vandetanib (ZACTIMA, ZD6474) With Hypofractionated Stereotactic Radiotherapy in Patients With Recurrent Malignant Gliomas[NCT00822887]Phase 113 participants (Actual)Interventional2007-03-31Completed
Hypofractionated Stereotactic Radiation Treatments (SBRT) on Children, Teenagers and Young Adults Malignant Tumors[NCT02013297]61 participants (Actual)Interventional2013-12-03Completed
A Phase II Study of Temozolomide in the Treatment of Children With High Grade Glioma[NCT00028795]Phase 2170 participants (Actual)Interventional2002-12-31Completed
A Phase II, Multicenter, Study for Newly Diagnosed Glioblastomas Using Boron Neutron Capture Therapy, Additional X-ray Treatment and Chemotherapy[NCT00974987]Phase 232 participants (Actual)Interventional2009-09-01Completed
Phase II Single Arm Trial of VEGF Trap in Patients With Recurrent Temozolomide-Resistant Malignant Gliomas[NCT00369590]Phase 258 participants (Actual)Interventional2006-08-31Completed
REGULATory T-Cell Inhibition With Basiliximab (Simulect®) During Recovery From Therapeutic Temozolomide-induced Lymphopenia During Antitumor Immunotherapy Targeted Against Cytomegalovirus in Patients With Newly-Diagnosed Glioblastoma Multiforme[NCT00626483]Phase 134 participants (Actual)Interventional2007-04-24Completed
A Phase II Study of Bevacizumab in Combination With Metronomic Temozolomide for Recurrent Malignant Glioma[NCT00501891]Phase 232 participants (Actual)Interventional2007-07-31Completed
A Phase 1b Study of AdV-tk + Valacyclovir Gene Therapy in Combination With Standard Radiation Therapy for Malignant Gliomas[NCT00751270]Phase 115 participants (Actual)Interventional2005-11-30Completed
Valproic Acid for Children With Recurrent and Progressive Brain Tumors[NCT01861990]Phase 10 participants (Actual)Interventional2013-05-31Withdrawn (stopped due to Feasibility of the trial was proven to be absent.)
A Multi-center, Prospective, Observational Study of Analysis of Q Cell Markers in Patients With Newly Diagnosed Primary Glioblastoma (Phase IV)[NCT02047058]240 participants (Anticipated)Observational [Patient Registry]2014-03-31Not yet recruiting
Whole Brain Radiotherapy in Combination With Gefitinib (Iressa) or Temozolomide (Temodal) for Brain Metastases From Non-Small Lung Cancer (NSCLC) A Randomized Phase II Trial[NCT00238251]Phase 259 participants (Actual)Interventional2005-05-31Completed
IMRT Combined With Erlotinib Compared With Whole-brain Radiotherapy for EGFR Wild Type Non-small Cell Lung Cancer With 4-10 Brain Metastases[NCT02556593]Phase 212 participants (Actual)Interventional2015-09-30Terminated
A Phase I Study of Temozolomide and RAD001C in Patients With Malignant Glioblastoma Multiforme[NCT00387400]Phase 132 participants (Actual)Interventional2007-03-20Completed
Phase II Randomized Study: Whole Brain Radiotherapy and Concomitant Temozolomide, Compared With Whole Brain Radiotherapy for Brain Metastases Treatment[NCT01015534]Phase 255 participants (Actual)Interventional2006-01-31Completed
Phase I Study of Enzastaurin and Temozolomide in Patients With Gliomas[NCT00516607]Phase 128 participants (Actual)Interventional2007-07-31Active, not recruiting
Role of Glutamate-mediate Excitotoxicity in Invasion and Progression Processes of Glioblastoma Multiforme[NCT05775458]50 participants (Anticipated)Observational2020-06-01Recruiting
Anhydrous Enol-Oxaloacetate (AEO) on Improving Fatigue in Post-COVID-19 Survivors[NCT04592354]40 participants (Anticipated)Interventional2020-10-15Recruiting
A Phase 2, Randomized, Open-Label Study of Anhydrous Enol-Oxaloacetate in Subjects With Newly Diagnosed Glioblastoma Multiforme[NCT04450160]Phase 280 participants (Anticipated)Interventional2020-12-31Not yet recruiting
A Randomized Double Blind Placebo Controlled Trial to Determine the Effects of Oxaloacetate on Improving Fatigue in ME/CFS[NCT05273372]80 participants (Anticipated)Interventional2022-03-15Enrolling by invitation
Hypofractionated IMRT (VMAT-RA) With Temozolomide for Patients With Newly Diagnosed High Grade Glioma (HGG)[NCT02082119]82 participants (Actual)Interventional2013-07-31Completed
A Phase I Dose Per Fraction Escalation Study of Hypofractionated Intensity-Modulated Radiation Therapy (Hypo-IMRT) Combining With Temozolomide (TMZ) Chemotherapy for Patients With Newly Diagnosed Glioblastoma Multiforme (GBM)[NCT00792012]Phase 137 participants (Actual)Interventional2005-11-30Completed
A Safety Run-in/Randomized Phase II Trial of EMD 121974 in Conjunction With Concomitant and Adjuvant Temozolomide With Radiation Therapy in Patients With Newly Diagnosed Glioblastoma Multiforme[NCT00085254]Phase 1/Phase 2112 participants (Actual)Interventional2005-04-30Completed
A Phase II Study of Concurrent Radiation Therapy, Temozolomide, and Bevacizumab Followed by Bevacizumab/Everolimus in the First-line of Treatment of Patients With Glioblastoma Multiforme[NCT00805961]Phase 268 participants (Actual)Interventional2009-01-31Completed
A Feasibility Pilot Trial Evaluating Caloric Restriction for Oncology Research in Early Stage Breast Cancer Patients[NCT01819233]38 participants (Actual)Interventional2013-03-08Completed
Can Fasting Decrease the Side Effects of Chemotherapy?[NCT04027478]39 participants (Anticipated)Interventional2019-09-01Enrolling by invitation
A Phase II Study of Hypofractionated Stereotactic Radiotherapy Combined With Anlotinib in Patients With Recurrent High-Grade Glioma[NCT04197492]Phase 232 participants (Anticipated)Interventional2019-12-16Recruiting
A Phase II Trial of Continuous Low-Dose Temozolomide for Patients With Recurrent Malignant Glioma[NCT00498927]Phase 247 participants (Actual)Interventional2007-06-30Completed
PPX and Concurrent Radiation for Newly Diagnosed Glioblastoma Without MGMT Methylation: A Randomized Phase II Study[NCT01402063]Phase 263 participants (Actual)Interventional2011-09-30Completed
A Pilot Study Investigating Neoadjuvant Temozolomide-based Proton Chemoradiotherapy for High-Risk Soft Tissue Sarcomas[NCT00881595]Phase 20 participants (Actual)Interventional2009-02-28Withdrawn (stopped due to No patients accrued since study opened)
Second Line Chemotherapy With Temozolomide in Recurrent Oligodendroglial Tumors After PCV-Chemotherapy[NCT00003304]Phase 229 participants (Anticipated)Interventional1998-04-30Completed
A Phase II Study of TEMOZOLOMIDE in Advanced Non-Small Cell Lung Cancer With and Without Brain Metastases[NCT00003062]Phase 270 participants (Anticipated)Interventional1997-07-31Completed
First Line Chemotherapy With Temozolomide in Recurrent Oligodendroglial Tumors, a Phase II Trial[NCT00003731]Phase 239 participants (Actual)Interventional1998-12-31Completed
Thalidomide to Chemotherapy Related Nausea and Vomiting in Pancreatic Cancer[NCT06017284]Phase 3100 participants (Anticipated)Interventional2023-11-01Recruiting
A Phase I/II Study of Temozolamide and Thalidomide in the Treatment of Advanced Melanoma[NCT00005815]Phase 1/Phase 20 participants Interventional1999-12-31Completed
A Phase II Trial of Temozolomide and BCNU for Anaplastic Gliomas[NCT00003176]Phase 282 participants Interventional1998-03-25Completed
Using Genomic Analysis to Guide Individual Treatment in Glioblastoma[NCT02725684]36 participants (Actual)Observational2015-03-12Completed
Phase II, Single Arm, Open Label Clinical Trial With Irinotecan in Combination With Cisplatin in Pediatric Patients With Unfavorable Prognosis Gliomas[NCT01574092]Phase 239 participants (Actual)Interventional2009-11-30Completed
A Phase III Randomized Study (Phase I Closed) of Radiation Therapy and Temozolomide Versus Radiation Therapy and Nitrosourea for Anaplastic Astrocytoma And Mixed Anaplastic Oligoastrocytoma (Astrocytoma Dominant)[NCT00004259]Phase 3230 participants (Actual)Interventional2000-06-30Completed
[NCT05491928]0 participants Expanded AccessAvailable
Randomized Open-label Trial of Dose Dense, Fixed Dose Capecitabine Compared to Standard Dose Capecitabine in Metastatic Breast Cancer and Advanced/Metastatic Gastrointestinal Cancers.[NCT02595320]Phase 2200 participants (Actual)Interventional2015-10-05Active, not recruiting
Prospective Randomized Placebo-Controlled Trial of SurVaxM Plus Adjuvant Temozolomide for Newly Diagnosed Glioblastoma (SURVIVE)[NCT05163080]Phase 2265 participants (Anticipated)Interventional2021-11-18Recruiting
Phase I/II Study of the Combination of BKM120 and Bevacizumab in Patients With Refractory Solid Tumors (Phase I) and Relapsed/Refractory Glioblastoma Multiforme (Phase II)[NCT01349660]Phase 1/Phase 288 participants (Actual)Interventional2011-12-31Completed
Immunophenotype Characterization of Circulating and Tumor Infiltrating Immune Cells in Malignant Brain Tumors.[NCT05831631]200 participants (Anticipated)Observational2022-08-01Recruiting
Phase I Trial of Zotiraciclib (TG02) Plus Dose-Dense or Metronomic Temozolomide Followed by Randomized Phase II Trial of Zotiraciclib (TG02) Plus Temozolomide Versus Temozolomide Alone in Adults With Recurrent Anaplastic Astrocytoma and Glioblastoma[NCT02942264]Phase 1/Phase 253 participants (Actual)Interventional2016-12-14Completed
Role of Repeat Resection in Recurrent Glioblastoma (4rGBM) Trial: a Randomized Care Trial for Patients With Recurrent GBM[NCT04838782]250 participants (Anticipated)Interventional2021-08-26Recruiting
Comparative Assessment of Methods to Analyze MGMT as a Predictive Factor of Response to Temozolomide in Glioblastomas.[NCT01345370]300 participants (Actual)Observational2009-03-31Completed
(Cost)Effectiveness of MR-guided LITT Therapy in Patients With Primary Irresectable Glioblastoma: a Prospective Multicenter Randomized Controlled Trial (EMITT)[NCT05318612]Phase 3238 participants (Anticipated)Interventional2022-04-08Recruiting
Prospective, Phase II Clinical Trial to Evaluate Efficacy and Safety of Autologous Dendritic Cell Vaccination in Glioblastoma Multiforme Patients After Complete Surgical Resection With Fluorescence Microscope[NCT01006044]Phase 226 participants (Actual)Interventional2009-10-31Completed
A Phase I Study of Repeated Neural Stem Cell Based Virotherapy in Combination With N-Acetylcysteine Amid (NACA) and Standard Radiation and Chemotherapy for Newly Diagnosed High Grade Glioma[NCT06169280]Phase 120 participants (Anticipated)Interventional2024-01-02Not yet recruiting
Evaluating the Expression Levels of microRNA-10b in Patients With Gliomas[NCT01849952]200 participants (Anticipated)Observational2020-02-28Recruiting
Phase I Study of Escalated Pharmacologic Dose, of Oral Folinic Acid in Combination With Temozolomide, According to Stupp R. Regimen, in Patients With Operated Grade-IV Astocytoma and a Non-methylated Gene Status of MGMT.[NCT01700569]Phase 124 participants (Actual)Interventional2013-01-31Terminated (stopped due to changing the standard of care)
Temozolomide and Irinotecan Consolidation in Patients With MGMT Silenced, Microsatellite Stable Colorectal Cancer With Persistence of Minimal Residual Disease in Liquid Biopsy After Standard Adjuvant Chemotherapy: the ERASE-TMZ Study[NCT05031975]Phase 235 participants (Anticipated)Interventional2022-05-02Recruiting
Prospective, Randomized Controlled Trial of Surgical Resection Prior to Bevacizumab Therapy for Recurrent Glioblastoma Multiforme[NCT01413438]Phase 20 participants (Actual)Interventional2011-07-15Withdrawn
A Phase I/II Study of the Safety and Feasibility of Administering T Cells Expressing Anti-EGFRvIII Chimeric Antigen Receptor to Patients With Malignant Gliomas Expressing EGFRvIII[NCT01454596]Phase 1/Phase 218 participants (Actual)Interventional2012-05-16Completed
Open-label Phase 1/2 (Safety Lead-in) Study of Trans Sodium Crocetinate (TSC) With Concomitant Treatment of Fractionated Radiation Therapy and Temozolomide in Newly Diagnosed Glioblastoma (GBM) Patients to Evaluate Safety and Efficacy[NCT01465347]Phase 1/Phase 259 participants (Actual)Interventional2012-02-29Completed
A Phase II, Randomized, Open-Label, Parallel-Group Study to Evaluate the Efficacy and Safety of Autologous Dendritic Cell Vaccination (ADCV01) as an Add-On Treatment for Primary Glioblastoma Multiforme (GBM) Patients[NCT04115761]Phase 224 participants (Anticipated)Interventional2019-06-06Recruiting
Re-irradiation of High Grade Gliomas: a Quality of Life Study[NCT01711580]0 participants (Actual)Observational2013-03-31Withdrawn (stopped due to Another study was commenced for this patient group)
Assessment of MGMT Promoter Methylation and Clinical Benefit From Temozolomide-based Therapy in Ewing Sarcoma Patients[NCT03542097]82 participants (Actual)Observational2014-04-15Completed
Phase 1b Trial of 5-fluorouracil, Leucovorin, Irinotecan in Combination With Temozolomide (FLIRT) and Bevacizumab for the First-line Treatment of Patients With MGMT Silenced, Microsatellite Stable Metastatic Colorectal Cancer.[NCT04689347]Phase 118 participants (Anticipated)Interventional2021-01-01Recruiting
Treatment of Newly Diagnosed High-Grade Gliomas in Patients Ages Greater Than or Equal to 3 and Less Than or Equal to 21 Years With a Phase II Irinotecan Window Followed by Radiation Therapy and Temozolomide[NCT00004068]Phase 253 participants (Actual)Interventional1999-03-31Completed
Phase I Study of Erlotinib and Temsirolimus in Resistant Solid Malignancies[NCT00770263]Phase 146 participants (Actual)Interventional2009-05-31Completed
An International, Randomized, Open-label Phase I/II Study of Vismodegib in Combination With Temozolomide Versus Temozolomide Alone in Adult Patients With Recurrent or Refractory Medulloblastomas Presenting an Activation of the Sonic Hedgehog (SHH) Pathway[NCT01601184]Phase 1/Phase 224 participants (Actual)Interventional2012-06-30Terminated (stopped due to The number of successes is not reached at the end of first stage of the phase II. The study is stopped.)
A Phase II Study in Relapsing Glioblastoma of Intraarterial Concurrent Chemoradiation Therapy Using IA Carboplatin[NCT03672721]Phase 1/Phase 235 participants (Anticipated)Interventional2018-07-10Recruiting
Phase II Evaluation of Temozolomide (SCH52365) and Thalidomide for the Treatment of Recurrent and Progressive Glioblastoma Multiforme[NCT00006358]Phase 244 participants (Actual)Interventional2000-06-13Completed
Phase I Trial of Combination of DNX-2401 (Formerly Named Delta-24-RGD) Oncolytic Adenovirus With a Short Course of Temozolomide for Treatment of Glioblastoma at First Recurrent[NCT01956734]Phase 131 participants (Anticipated)Interventional2013-09-30Completed
Monoinstitutional Phase II Trial Addressing Tolerability and Activity of RCHOP Chemoimmunotherapy Preceded by BBB Permeabilization by t-NGR Necrosis Factor in Patients With Relapsed/Refractory Primary Central Nervous System Lymphoma[NCT03536039]Phase 228 participants (Actual)Interventional2016-01-27Completed
Clinical Efficacy and Safety of IBER Salvage Treatment Followed by Ibrutinib Maintenance for Transplant-ineligible Patients With Relapsed or Refractory Primary Central Nervous System Lymphoma (PCNSL): a Multicenter, Single-arm, Prospective Phase II Study[NCT04066920]Phase 230 participants (Anticipated)Interventional2019-10-01Not yet recruiting
Phase Ⅱ Trial of Temozolomide Plus Concurrent Whole-Brain Radiation Followed by TNV Regimen as Adjuvant Therapy for Patients With Newly Diagnosed Primary Central Nervous System (CNS) Lymphoma (PCNSL)[NCT01735747]Phase 216 participants (Anticipated)Interventional2008-06-30Active, not recruiting
A Phase II, Open Label, Single Arm Study of Nivolumab for Recurrent or Progressive IDH Mutant Gliomas With Prior Exposure to Alkylating Agents[NCT03557359]Phase 220 participants (Actual)Interventional2018-06-12Active, not recruiting
A Phase I Study Of ZD 1839 And Temozolomide For The Treatment Of Gliomas[NCT00027625]Phase 10 participants Interventional2002-01-28Completed
A Phase I Study of Mebendazole for the Treatment of Pediatric Gliomas[NCT01837862]Phase 1/Phase 236 participants (Anticipated)Interventional2013-10-22Recruiting
A Phase I/II Trial Of Temozolomide And Vinorelbine For Patients With Recurrent Brain Metastases[NCT00026494]Phase 1/Phase 249 participants (Actual)Interventional2001-07-31Completed
Phase I-II Trial of CPT-11 and Temozolomide (Temodar) in Patients With Recurrent Malignant Glioma[NCT00006025]Phase 10 participants Interventional2001-01-05Completed
Phase I Study of Continuous Dosing of Sunitinib in Non GIST Sarcomas With Concomitant Radiotherapy[NCT01308034]Phase 125 participants (Actual)Interventional2011-03-31Completed
A Phase I Study of Imatinib Mesylate in Combination With Temozolomide in Patients With Malignant Glioma[NCT00354068]Phase 165 participants (Actual)Interventional2004-07-31Completed
Phase II Study Of Temozolomide, Thalidomide And Celecoxib In Patients With Newly Diagnosed Glioblastoma Multiforme In The Post-Radiation Setting[NCT00047294]Phase 20 participants Interventional2001-04-30Completed
Imaging After Stereotactic Radiosurgery for Brain Metastases or Primary Tumor Can Hybrid PET-MRI Differentiate Between Radiation Effects and Disease ?[NCT03068520]140 participants (Anticipated)Interventional2017-03-01Recruiting
A Phase I Study of Temozolomide and CCNU in Pediatric Patients With Newly Diagnosed Incompletely Resected Non-Brainstem High-Grade Gliomas[NCT00006024]Phase 132 participants (Actual)Interventional2000-11-30Completed
Phase II Study of Gamma Knife Radiosurgery and Temozolomide (Temodar) for Newly Diagnosed Brain Metastases[NCT00582075]Phase 225 participants (Actual)Interventional2002-07-31Completed
A Phase I Study of ABT-888, an Oral Inhibitor of Poly(ADP-Ribose) Polymerase and Temozolomide in Children With Recurrent/Refractory CNS Tumors[NCT00994071]Phase 19 participants (Actual)Interventional2009-09-22Completed
A Phase II Study of Temozolomide (SCH 52365, Temodal(R)) for the Treatment of Recurrent Malignant Glioma[NCT00004113]Phase 20 participants Interventional1999-06-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Maximum Tolerated Dose (MTD) of Afatinib

The MTD was defined as the highest afatinib dose level, at which no more than 1 out of 6 patients experienced drug-related DLT, i.e. the highest afatinib dose with a DLT incidence ≤17%. A separate MTD was determined for afatinib and RT (Regimen U), and for afatinib, TMZ, and RT (Regimen M). (NCT00977431)
Timeframe: 6 weeks

InterventionMilligram (mg) (Number)
Total - Regimen M30
Total - Regimen U40

Number of Patients With Investigator Defined Dose Limiting Toxicities (DLT) During the RT Phase

"Adverse event (AE) related to afatinib with any one criteria; Hematological: Common terminology criteria for adverse events (CTCAE) Grade 4 neutropenia (Absolute neutrophil count, including bands <500/cubic millimeter (mm³)) for >7 days, CTCAE Grade 3 or 4 neutropenia of any duration associated with fever >38.3 Celsius, CTCAE Grade 3 thrombocytopenia (platelet count <50000 - 25000/mm³), All other toxicities of CTCAE Grade ≥3 leading interruption of treatment > 14 days.~Non-hematological: CTCAE Grade ≥3 nausea or vomiting despite appropriate use of standard anti-emetics for ≥3 days, CTCAE Grade ≥3 diarrhea despite appropriate use of standard anti-diarrheal therapy for ≥3 days, CTCAE Grade ≥3 rash despite standard medical management and lasting >7 days, CTCAE Grade ≥2 cardiac left ventricular function, CTCAE Grade ≥2 worsening of renal function as measured by serum creatinine, newly developed proteinuria or decrease in glomerular filtration rate, All other toxicities of CTCAE Grade ≥3. (NCT00977431)
Timeframe: 6 weeks

InterventionParticipants (Number)
Afatinib 20 Milligram, Radiotherapy + Temozolomide - Regimen M1
Afatinib 30 mg, Radiotherapy + Temozolomide - Regimen M0
Afatinib 40 mg, Radiotherapy + Temozolomide - Regimen M2
Afatinib 20 mg, Radiotherapy - Regimen U0
Afatinib 40 mg, Radiotherapy - Regimen U1

Concentration of Afatinib in Plasma at Steady State Pre-dose on Days 8, 15 and 29

Concentration of afatinib in plasma at steady state pre-dose (Cpre,ss) on days 8, 15 and 29. (NCT00977431)
Timeframe: Pharmacokinetic blood sample were taken at 5 minutes before drug on days 8, 15 and 29 and 1, 3 and 6 hours after drug administration on day 15

,,,,
Interventionnanograms per milliliter (ng/mL) (Geometric Mean)
Cpre, ss, 8Cpre, ss, 15Cpre, ss, 29
Afatinib 20 mg, Radiotherapy - Regimen U4.94.45.0
Afatinib 20 Milligram, Radiotherapy + Temozolomide - Regimen M4.45.65.3
Afatinib 30 mg, Radiotherapy + Temozolomide - Regimen M10.79.617.8
Afatinib 40 mg, Radiotherapy - Regimen U16.718.916.1
Afatinib 40 mg, Radiotherapy + Temozolomide - Regimen M15.716.817.4

Incidence and Intensity of Adverse Events (AE) According to Common Terminology Criteria of Adverse Events (CTCAE v.3.0)

Incidence and intensity of adverse events (AE) according to Common Terminology Criteria of Adverse Events (CTCAE v.3.0). The CTCAE grades are: 1 (mild AE), 2 (moderate AE), 3 (severe AE), 4 (life-threatening or disabling AE), 5 (death related to AE). (NCT00977431)
Timeframe: From the first administration of trial medication until 4 weeks after the last administration of trial medication, up to approximately 338 weeks

,,,,
InterventionParticipants (Number)
Grade 1Grade 2Grade 3Grade 4Grade 5
Afatinib 20 mg, Radiotherapy - Regimen U01200
Afatinib 20 Milligram, Radiotherapy + Temozolomide - Regimen M00430
Afatinib 30 mg, Radiotherapy + Temozolomide - Regimen M02400
Afatinib 40 mg, Radiotherapy - Regimen U12523
Afatinib 40 mg, Radiotherapy + Temozolomide - Regimen M11410

The Objective Tumour Response According to the Macdonald Criteria

Objective response was defined as a best overall response of complete response (CR) or partial response (PR). The best overall response was the best overall response to trial medication according to the Macdonald criteria recorded since the first administration of trial medication and until the earliest of disease progression, death, or start of further anti-cancer treatment. Tumour response was assessed based on local radiological image evaluation by the investigators according to the Macdonald criteria: Complete Response (CR): Disappearance of all enhancing tumour on consecutive Magnetic resonance imaging (MRI) scans at least 28 days apart, off steroids, and neurologically stable or improved. Partial Response (PR): At least 50% reduction in size of enhancing tumour on consecutive MRI scans at least 28 days apart, steroids stable or reduced, and neurologically stable or improved. (NCT00977431)
Timeframe: From the first administration of trial medication until 4 weeks after the last administration of trial medication, up to approximately 338 weeks

,,,,
InterventionParticipants (Number)
NoYesMissing
Afatinib 20 mg, Radiotherapy - Regimen U300
Afatinib 20 Milligram, Radiotherapy + Temozolomide - Regimen M520
Afatinib 30 mg, Radiotherapy + Temozolomide - Regimen M330
Afatinib 40 mg, Radiotherapy - Regimen U1012
Afatinib 40 mg, Radiotherapy + Temozolomide - Regimen M502

Overall Survival as Measured From the Day of Randomization

The duration of survival is the time interval between randomization and the date of death due to any cause. Patients not reported dead or lost to follow up will be censored at the date of the last follow up examination. (NCT00626990)
Timeframe: from date from enrollment till the date of death (time till death is up to 10.9 years after patient enrollment in the study)

InterventionMonths (Median)
Absence of Concomitant Temozolomide (TMZ)60.42
Presence of Concomitant Temozolomide (TMZ)66.92
Absence of Adjuvant Temozolomide (TMZ)46.92
Presence of Adjuvant Temozolomide (TMZ)82.33

Progression-free Survival

Disease progression is defined as radiological or neurological/clinical progression (whichever occurs first); progression free survival (PFS) is the time interval between the date of randomization and the date of disease progression or death whichever occurs first. If neither event has been observed, the patient is censored at the date of the last follow up examination. Radiological progression was defined as increase of contrast enhancing area on MRI or CT scans of more than 25% as measured by two perpendicular diameters compared to the smallest measurements ever recorded for the same lesion by the same technique. The appearance of new lesions with or without contrast enhancement Neurological/clinical progression was defined as:decrease in WHO performance status,deterioration of neurological functions,appearance of signs/symptoms of increased intracranial pressure,and/or start of corticosteroid or increase of corticosteroid dosage by 50% for control of neurological symptoms. (NCT00626990)
Timeframe: from randomization till the date of disease progression or death (time till death is up to 10.9 years after patient enrollment in the study)

InterventionMonths (Median)
Absence of Concomitant TMZ20.9
Presence of Concomitant TMZ33.02
Absence of Adjuvant TMZ19.09
Presence of Adjuvant TMZ42.81

Overall Survival (OS) Rates at 12 Months

Overall Survival (OS) rate is defined as the percentage of participants surviving at 12 months (NCT02667587)
Timeframe: From randomization to 12 months after first dose

Interventionpercentage of participants (Number)
Radiotherapy, Temozolomide Plus Nivolumab82.7
Radiotherapy, Temozolomide Plus Placebo87.7

Overall Survival (OS) Rates at 24 Months

Overall Survival (OS) rate is defined as the percentage of participants surviving at 24 months (NCT02667587)
Timeframe: From randomization to 24 months after first dose

Interventionpercentage of participants (Number)
Radiotherapy, Temozolomide Plus Nivolumab55.9
Radiotherapy, Temozolomide Plus Placebo63.3

Progression Free Survival (PFS) Based on Investigator Assessment

The time from randomization to the date of the first documented tumor progression or death by any cause. PFS will be determined by investigator assessment based Radiologic Assessment in Neuro-Oncology (RANO) criteria. Specifically, RANO response criteria indicates that within the first 12 weeks of completion of radiotherapy, progression can only be assessed if the majority of the new enhancement is outside of the radiation field or if there is pathologic confirmation of progressive disease. (NCT02667587)
Timeframe: From randomization to the date of the first documented tumor progression or death by any cause. (up to approximately 4.5 years)

InterventionMonths (Median)
Radiotherapy, Temozolomide Plus Nivolumab14.09
Radiotherapy, Temozolomide Plus Placebo15.18

Progression-free Survival (PFS) Determined by BICR

The time from randomization to the date of the first documented tumor progression or death by any cause. PFS will be determined by a Blinded Independent Central Review (BICR) assessed based on Radiologic Assessment in Neuro-Oncology (RANO) criteria. Specifically, RANO response criteria indicates that within the first 12 weeks of completion of radiotherapy, progression can only be assessed if the majority of the new enhancement is outside of the radiation field or if there is pathologic confirmation of progressive disease. (NCT02667587)
Timeframe: From randomization to the date of the first documented tumor progression or death by any cause. (up to approximately 4.5 years)

InterventionMonths (Median)
Radiotherapy, Temozolomide Plus Nivolumab10.64
Radiotherapy, Temozolomide Plus Placebo10.32

Overall Survival (OS)

The time from the date of randomization to the date of death. who have not died by the end of the study will be censored to last known date alive. OS is assessed in the randomized population with no corticosteroids at baseline population and in the overall randomized population. (NCT02667587)
Timeframe: From randomization to date of death (up to approximately 4.5 years)

,
InterventionMonths (Median)
All randomized participantsAll randomized participants without baseline corticosteroids
Radiotherapy, Temozolomide Plus Nivolumab28.9131.34
Radiotherapy, Temozolomide Plus Placebo32.0732.99

Phase I: Maximum Tolerated Dose (MTD) of Temozolomide (TMZ) When Used With T-DM1 (Ado-trastuzumab)

Maximum tolerated dose of TMZ when used in combination with T-DM1. MTD is defined as the dose level at which 0 or 1 participant in 6 has a dose limiting toxicity (DLT). A DLT is defined as grade 3 or higher non-hematologic adverse events excluding grade 3 hypertension controlled with anti-hypertensive therapy; or grade 3 asymptomatic electrolytes imbalance; grade 3 endocrinopathy; grade 3 asymptomatic increase in aspartate aminotransferase or alanine aminotransferase; and transient (lasting less than <48 hours) nausea, emesis, or diarrhea if corrected with conservative measures within 24-48 hours. A hematologic grade 4 neutropenia of ≥ 7 days duration, grade ≥ 3 thrombocytopenia, and all other grade 4 hematologic toxicities excluding grade 4 lymphopenia, or leukopenia in the absence of grade 3 or higher neutropenia. Grade 3 is severe. Grade 4 is life-threatening. (NCT03190967)
Timeframe: first 21 days of treatment

Interventionmg/m^2 (Number)
All Participants40

Phase I: Median Survival

Median amount of time participants survives after therapy. Survival compared between the two arms and Kaplan-Meier curves constructed with a two-tailed log-rank test used to compare the arms. (NCT03190967)
Timeframe: From date of first therapy until death, an average of 40.79 months

InterventionMonths (Median)
Level 1 Phase I: Ado-trastuzumab (T-DMI) 3.6 mg/kg + Temozolomide (TMZ) 30 mg/m^237.8
Level 2 Phase I: Ado-trastuzumab (T-DMI) 3.6 mg/kg + Temozolomide (TMZ) 40 mg/m^248.4
Level 3 Phase I: Ado-trastuzumab (T-DMI) 3.6 mg/kg + Temozolomide (TMZ) 50 mg/m^238.5

Phase I: Number of Participants With Dose Limiting Toxicity (DLTs) at Each Dose Level

Number of participants with DLTs at each dose level 30 days after treatment. A DLT is defined as grade 3 or higher non-hematologic adverse events excluding grade 3 hypertension controlled with anti-hypertensive therapy; or grade 3 asymptomatic electrolytes imbalance; grade 3 endocrinopathy; grade 3 asymptomatic increase in aspartate aminotransferase or alanine aminotransferase; and transient (lasting less than <48 hours) nausea, emesis, or diarrhea if corrected with conservative measures within 24-48 hours. A hematologic grade 4 neutropenia of ≥ 7 days duration, grade ≥ 3 thrombocytopenia, and all other grade 4 hematologic toxicities excluding grade 4 lymphopenia, or leukopenia in the absence of grade 3 or higher neutropenia. Grade 3 is severe. Grade 4 is life-threatening. (NCT03190967)
Timeframe: After first cycle of treatment, up to 30 days

InterventionParticipants (Count of Participants)
Level 1 Phase I: Ado-trastuzumab (T-DMI) 3.6 mg/kg + Temozolomide (TMZ) 30 mg/m^20
Level 2 Phase I: Ado-trastuzumab (T-DMI) 3.6 mg/kg + Temozolomide (TMZ) 40 mg/m^20
Level 3 Phase I:Ado-trastuzumab (T-DMI) 3.6 mg/kg + Temozolomide (TMZ) 50 mg/m^20

Phase I: Number of Participants With Serious and/or Non-serious Adverse Events Assessed by the Common Terminology Criteria for Adverse Events (CTCAE v4.0)

Here is the number of participants with serious and/or non-serious adverse events assessed by the Common Terminology Criteria for Adverse Events (CTCAE v4.0). A non-serious adverse event is any untoward medical occurrence. A serious adverse event is an adverse event or suspected adverse reaction that results in death, a life-threatening adverse drug experience, hospitalization, disruption of the ability to conduct normal life functions, congenital anomaly/birth defect or important medical events that jeopardize the patient or subject and may require medical or surgical intervention to prevent one of the previous outcomes mentioned. (NCT03190967)
Timeframe: Date treatment consent signed to date off study, approximately 44 months and 27 days for level 1, 28 months and 10 days for level 2, and 40 months and 8 days for level 3.

InterventionParticipants (Count of Participants)
Level 1 Phase I: Ado-trastuzumab (T-DMI) 3.6 mg/kg + Temozolomide (TMZ) 30 mg/m^23
Level 2 Phase I: Ado-trastuzumab (T-DMI) 3.6 mg/kg + Temozolomide (TMZ) 40 mg/m^23
Level 3 Phase I: Ado-trastuzumab (T-DMI) 3.6 mg/kg + Temozolomide (TMZ) 50 mg/m^26

Phase I: Standard Time to Progression (TTP)

TTP is the time between the first day of treatment to the day of disease progression. Progression was assessed using the Response Evaluation Criteria in Solid Tumors (RECIST). Progression is at least a 25% increase in the sum of products of all measurable lesions over smallest sum observed, clear worsening of any evaluable disease, appearance of any new lesion/site, or failure to return for evaluation due to death or deteriorating condition. (NCT03190967)
Timeframe: From first day of treatment to the day of disease progression, an average of 15 months.

InterventionMonths (Mean)
Level 1 Phase I: Ado-trastuzumab (T-DMI) 3.6 mg/kg + Temozolomide (TMZ) 30 mg/m^26.95
Level 2 Phase I:Ado-trastuzumab (T-DMI) 3.6 mg/kg + Temozolomide (TMZ) 40 mg/m^216.26
Level 3 Phase I:Ado-trastuzumab (T-DMI) 3.6 mg/kg + Temozolomide (TMZ) 50 mg/m^217.46

Phase I: Number of Participants With Grade 3 and/or Grade 4 Adverse Events

Adverse events were assessed by the Common Terminology Criteria for Adverse Events (CTCAE v4.0). Grade 3 is severe. Grade 4 is life-threatening. (NCT03190967)
Timeframe: Evaluated at the beginning of every cycle while on study, for an average of 9.6 months (range 2.8-33.9 months).

,,
InterventionParticipants (Count of Participants)
Grade 3 AnemiaGrade 3 Aspartate aminotransferase increasedGrade 3 CD4 lymphocytes decreasedGrade 3 DysphasiaGrade 3 HypokalemiaGrade 3 Lymphocyte count decreasedGrade 3 Neoplasms benign, malignant and unspecified (incl cysts and polyps) - Malignant Neoplasm-CMLGrade 3 Neutrophil count decreasedGrade 3 Platelet count decreasedGrade 3 Surgical and medical procedures - Other, Lap Cholecystectomy/Hernia RepairGrade 3 White blood cell decreasedGrade 4 White blood cell decreasedGrade 4 CD4 lymphocytes decreasedGrade 4 Lymphocyte count decreasedGrade 5
Level 1 Phase I: Ado-trastuzumab (T-DMI) 3.6 mg/kg + Temozolomide (TMZ) 30 mg/m^2001101000000000
Level 2 Phase I: Ado-trastuzumab (T-DMI) 3.6 mg/kg + Temozolomide (TMZ) 40 mg/m^2101002000000000
Level 3 Phase I:Ado-trastuzumab (T-DMI) 3.6 mg/kg + Temozolomide (TMZ) 50 mg/m^2015015111110220

Concordance Between Structural Versus Multimodal Imaging for CRRC-Assessed Event-Free Survival

Concordance is presented as the percentage of participants with concordance between assessments. EFS concordance was defined as event Structural assessment and Diffusion Perfusion assessment occurs within 28 days or no event Structural and no Diffusion Perfusion. (NCT01390948)
Timeframe: Up to 12 months

Interventionpercentage of participants (Number)
Chemoradiation + TMZ96.6
Chemoradiation + Bevacizumab + TMZ87.1

EFS as Assessed by the Investigator

EFS was defined as the time from randomisation to the earliest occurrence of any of the following: tumor progression, tumor recurrence, second primary non-HGG malignancy or death attributable to any cause. Tumor assessments were conducted using MRI and reviewed by the investigator using RANO criteria. Tumor progression was defined as clear clinical progression or >/= 25% increase in the sum of the products of perpendicular diameters of the contrast enhancing lesions compared with the smallest tumor measurement obtained either at baseline (if no decrease was observed) or best response and with the participant on stable or increasing doses of corticosteroids. Tumor recurrence was defined as recurrence after tumor was completely resected (no disease present at baseline). EFS was estimated using the Kaplan-Meier method. (NCT01390948)
Timeframe: From the time of randomization to the date of any defined event (up to 12 months)

Interventionmonths (Median)
Chemoradiation + TMZ11.79
Chemoradiation + Bevacizumab + TMZ11.27

Event-Free Survival (EFS) as Assessed by the Central Radiology Review Committee (CRRC)

EFS was defined as the time from randomisation to the earliest occurrence of any of the following: tumor progression, tumor recurrence, second primary non- HGG malignancy or death attributable to any cause. Tumor assessments were conducted using magnetic resonance imaging (MRI) and reviewed by the site-independent CRRC using Response Assessment in Neuro-Oncology (RANO) criteria. Tumor progression was defined as clear clinical progression or >/= 25% increase in the sum of the products of perpendicular diameters of the contrast enhancing lesions compared with the smallest tumor measurement obtained either at baseline (if no decrease was observed) or best response and with the subject on stable or increasing doses of corticosteroids. Tumor recurrence was defined as recurrence after tumor was completely resected (no disease present at baseline). EFS was estimated using the Kaplan-Meier method. (NCT01390948)
Timeframe: From the time of randomization to the date of any defined event (up to 12 months)

Interventionmonths (Median)
Chemoradiation + TMZ11.79
Chemoradiation + Bevacizumab + TMZ8.21

Neurological Psychological Function as Measured by the Wechsler Scale

The Wechsler Intelligence Scale for Children version IV (WISC-IV) was used to generate a full scale intelligence quotient (IQ) which represents a child's general intellectual ability. The average IQ score is 100, with lower scores representing lower intellectual ability. (NCT01390948)
Timeframe: End of treatment (approximately 58 weeks post-baseline)

Interventionunits on a scale (Mean)
Chemoradiation + TMZ92.0
Chemoradiation + Bevacizumab + TMZ97.0

Number of Radiotherapy Dose Administrations in the Concurrent Phase

Number of doses were assessed for the concurrent phase, which is the treatment period after the initial treatment phase and including the subsequent treatment break of approximately 4 weeks. (NCT01390948)
Timeframe: Beginning of the concurrent phase to end of treatment break (10 weeks)

InterventionGrays (Median)
Chemoradiation + TMZ54.0
Chemoradiation + Bevacizumab + TMZ54.0

Objective Response Rate (ORR)

ORR was defined as the percentage of participants with a complete response (CR) or partial response (PR) determined on two consecutive occasions >/= 4 weeks apart. Tumor assessments were conducted using MRI and reviewed by the site-independent CRRC using RANO criteria. The following were needed to qualify as CR: complete disappearance of all measurable enhancing lesions sustained for at least 4 weeks by MRI, no steroids above physiological levels, clinical status stable or improved compared to baseline. The following were needed to qualify as PR: ≥ 50% decrease from baseline in the sum of products of perpendicular diameters of all measurable enhancing lesions sustained for at least 4 weeks by MRI, steroid dose not increased compared to baseline, clinical status stable or improved compared to baseline. (NCT01390948)
Timeframe: From the time of randomization to the date of any defined event (up to 12 months)

Interventionpercentage of participants (Number)
Chemoradiation + TMZ40
Chemoradiation + Bevacizumab + TMZ41.7

Overall Survival

Overall Survival was defined as the time of diagnosis to the date of death due to any cause. Overall Survival was estimated using the Kaplan-Meier method. (NCT01390948)
Timeframe: From the time of randomization to the date of death (up to approximately 60 months)

Interventionmonths (Median)
Chemoradiation + TMZ20.27
Chemoradiation + Bevacizumab + TMZ18.30

Percentage of Participants With 1-Year Survival

1-year survival was estimated using the Kaplan-Meier method. (NCT01390948)
Timeframe: 1 year after end of treatment

Interventionpercentage of participants (Number)
Chemoradiation + TMZ67.69
Chemoradiation + Bevacizumab + TMZ74.83

Percentage of Participants With an Adverse Event (AE)

An AE was defined as any unfavorable and unintended sign (including an abnormal laboratory finding), symptom, or disease temporally associated with the use of a medicinal product, whether or not considered related to the medicinal product. (NCT01390948)
Timeframe: From the time of randomization of the first participant to the date of clinical cutoff (approximately 60 months)

Interventionpercentage of participants (Number)
Chemoradiation + TMZ100
Chemoradiation + Bevacizumab + TMZ98.3

Percentage of Participants With EFS as Determined by the CRRC at 1 Year

EFS was defined as the time from randomisation to the earliest occurrence of any of the following: tumor progression, tumor recurrence, second primary non- HGG malignancy or death attributable to any cause. Tumor assessments were conducted using MRI and reviewed by the site-independent CRRC using RANO criteria. Tumor progression was defined as clear clinical progression or >/= 25% increase in the sum of the products of perpendicular diameters of the contrast enhancing lesions compared with the smallest tumor measurement obtained either at baseline (if no decrease was observed) or best response and with the subject on stable or increasing doses of corticosteroids. Tumor recurrence was defined as recurrence after tumor was completely resected (no disease present at baseline). EFS was estimated using the Kaplan-Meier method. (NCT01390948)
Timeframe: 1 year

Interventionpercentage of participants (Number)
Chemoradiation + TMZ48.37
Chemoradiation + Bevacizumab + TMZ38.28

Percentage of Participants With EFS as Determined by the CRRC at 6 Months

EFS was defined as the time from randomisation to the earliest occurrence of any of the following: tumor progression, tumor recurrence, second primary non- HGG malignancy or death attributable to any cause. Tumor assessments were conducted using MRI and reviewed by the site-independent CRRC using RANO criteria. Tumor progression was defined as clear clinical progression or >/= 25% increase in the sum of the products of perpendicular diameters of the contrast enhancing lesions compared with the smallest tumor measurement obtained either at baseline (if no decrease was observed) or best response and with the subject on stable or increasing doses of corticosteroids. Tumor recurrence was defined as recurrence after tumor was completely resected (no disease present at baseline). EFS was estimated using the Kaplan-Meier method. (NCT01390948)
Timeframe: 6 months

Interventionpercentage of participants (Number)
Chemoradiation + TMZ66.46
Chemoradiation + Bevacizumab + TMZ68.43

Health Status as Measured by the Health Utility Index (HUI)

HUI is a preference-based, multi-attitude, health-related instrument specifically developed for use with children. HUI consists of eight attributes of health status: vision, hearing, speech, ambulation, dexterity, emotion, cognition and pain. Each attribute had 5 or 6 levels varying from highly impaired to normal. Each of the eight health dimensions was tested separately and a composite score ranging between 1 (perfect health) and 0 (death) was obtained for participants aged 5 years or older. (NCT01390948)
Timeframe: Baseline, Cycle 6 of the adjuvant phase, end of treatment (approximately 58 weeks post-baseline), and yearly during the follow-up period (maximum 5 years in follow-up)

Interventionunits on a scale (Mean)
BaselineCycle 6, Day 1End of TreatmentYearly Follow-Up 1Yearly Follow-up 2Additional Safety Follow-Up (Visit 2)Additional Safety Follow-Up (Visit 4)Additional Safety Follow-Up (Visit 6)Additional Safety Follow-Up (Visit 8)End of Study
Chemoradiation + Bevacizumab + TMZ0.7300.7790.8200.9260.7930.9010.8300.4900.9300.790

Health Status as Measured by the Health Utility Index (HUI)

HUI is a preference-based, multi-attitude, health-related instrument specifically developed for use with children. HUI consists of eight attributes of health status: vision, hearing, speech, ambulation, dexterity, emotion, cognition and pain. Each attribute had 5 or 6 levels varying from highly impaired to normal. Each of the eight health dimensions was tested separately and a composite score ranging between 1 (perfect health) and 0 (death) was obtained for participants aged 5 years or older. (NCT01390948)
Timeframe: Baseline, Cycle 6 of the adjuvant phase, end of treatment (approximately 58 weeks post-baseline), and yearly during the follow-up period (maximum 5 years in follow-up)

Interventionunits on a scale (Mean)
BaselineCycle 6, Day 1End of TreatmentYearly Follow-Up 1Yearly Follow-up 2Additional Safety Follow-Up (Visit 2)Additional Safety Follow-Up (Visit 4)Additional Safety Follow-Up (Visit 6)End of Study
Chemoradiation + TMZ0.7130.7850.8320.9060.7370.7840.8141.0000.647

Number of Dose Administrations of TMZ and Bevacizumab in the Concurrent Phase

Number of doses were assessed for the concurrent phase, which is the treatment period after the initial treatment phase and including the subsequent treatment break of approximately 4 weeks. (NCT01390948)
Timeframe: Beginning of the concurrent phase to end of treatment break (10 weeks)

,
Interventionnumber of dose administrations (Median)
TMZBevacizumab
Chemoradiation + Bevacizumab + TMZ42.06.0
Chemoradiation + TMZ42.0NA

Percentage of Participants Who Completed >/= 90% of Planned Radiotherapy and TMZ Administrations

(NCT01390948)
Timeframe: From the time of randomization of the first participant to the date of clinical cutoff (approximately 60 months)

,
Interventionpercentage of participants (Number)
RadiotherapyTMZ
Chemoradiation + Bevacizumab + TMZ98.388.3
Chemoradiation + TMZ94.685.7

Percentage of Participants With a Treatment Delay or Discontinuation

(NCT01390948)
Timeframe: From the time of randomization of the first participant to the date of clinical cutoff (approximately 60 months)

,
Interventionpercentage of participants (Number)
AE leading to dose modification/interruptionAE leading to withdrawal from treatment
Chemoradiation + Bevacizumab + TMZ71.721.7
Chemoradiation + TMZ60.75.4

Adult Study: Objective Response Rate (ORR)

The objective response rate (ORR) included best overall responses - complete response (CR) and partial response (PR) - assessed by the independent review committee per response assessment in neurooncology criteria (RANO) criteria from the date of randomization until disease progression or death, whichever came first. All objective responses (CR and PR) must be have been confirmed by repeat MRI 4 weeks after the first time when CR or PR is identified. Any subject who did not meet CR or PR including those who did not have post-baseline radiological assessments was considered a nonresponder. (NCT02343406)
Timeframe: Every 8 weeks at each assessment of disease, up to 28 months

Interventionpercentage of participants (Number)
ABT-414/Temozolomide14.3
ABT-414_adult7.7
Control (Temozolomide/Lomustine)4.4

Pediatric Study: Area Under the Concentration-time Curve (AUC) Observed for ABT-414

AUC is a measure of how long and how much drug is present in the body after dosing. The AUC of depatuxizumab mafodotin (ABT-414) in the pediatric population was measured following treatment to confirm that this was comparable to adults, and that the dosing levels are appropriate for a pediatric population. (NCT02343406)
Timeframe: Samples collected Cycle 1 Days 1, 2,3,5,8,15; Cycle 2 Day 1; Cycle 3 Day 1; Cycle 5 Day 1; Day 1 of every two cycles starting with Cycle 5; and 35 days after the last dose

Interventionµg*h/mL (Mean)
ABT-414_ Pediatric3170

Pediatric Study: Area Under the Concentration-time-curve (AUC) Observed for Unconjugated Cys-mcMMAF

AUC is a measure of how long and how much drug or drug metabolite is present in the body after dosing. The AUC of Cys-mcMMAF, a toxic metabolite of depatuxizumab mafodotin, in the pediatric population was measured following treatment to confirm that this was comparable to adults, and that the dosing levels are appropriate for a pediatric population. (NCT02343406)
Timeframe: Samples collected Cycle 1 Days 1, 2, 3, 5, 8

Interventionng*h/mL (Mean)
ABT-414_ Pediatric14.1

Pediatric Study: Half-life (t1/2) Observed for ABT-414

Half-life is the calculated time it takes for half of the drug to leave the body. (NCT02343406)
Timeframe: Samples collected Cycle 1 Days 1, 2,3,5,8,15; Cycle 2 Day 1; Cycle 3 Day 1; Cycle 5 Day 1; Day 1 of every two cycles starting with Cycle 5; and 35 days after the last dose

Interventiondays (Mean)
ABT-414_ Pediatric9.0

Pediatric Study: Half-life (t1/2) Observed for Cys-mcMMAF

Half-life is the calculated time it takes for half of the drug or drug metabolite to leave the body. CysmcMMAF is a toxic metabolite of depatuxizumab mafodotin. (NCT02343406)
Timeframe: Samples collected Cycle 1 Days 1, 2, 3, 5, 8

Interventiondays (Mean)
ABT-414_ Pediatric11.2

Pediatric Study: Maximum Observed Plasma Concentration (Cmax) of Cys-mcMMAF

Cmax is the peak concentration that a drug or drug metabolite achieves in a specified compartment after the drug has been administrated and before administration of a second dose. Cys-mcMMAF is a toxic metabolite of depatuxizumab mafodotin. (NCT02343406)
Timeframe: Samples collected Cycle 1 Days 1, 2, 3, 5, 8

Interventionng/mL (Mean)
ABT-414_ Pediatric0.272

Pediatric Study: Maximum Observed Serum Concentration (Cmax) of ABT-414

Cmax is the peak concentration that a drug achieves in a specified compartment after the drug has been administrated and before administration of a second dose. (NCT02343406)
Timeframe: Samples collected Cycle 1 Days 1, 2,3,5,8,15; Cycle 2 Day 1; Cycle 3 Day 1; Cycle 5 Day 1; Day 1 of every two cycles starting with Cycle 5; and 35 days after the last dose

Interventionµg/mL (Mean)
ABT-414_ Pediatric31.4

Pediatric Study: Percentage of Participants With Adverse Events From the First Visit Until 49 Days After the Last Dose of Study Drug

The severity of each adverse event was rated according to the National Cancer Institute Common Terminology Criteria for Adverse Events (NCI CTCAE Version 4.0) (NCT02343406)
Timeframe: From participant's first visit until 49 days after the participant's last dose of study drug, up to 63 weeks

Interventionpercentage of participants (Number)
ABT-414_ Pediatric100

Adult Study: Overall Survival (OS)

Overall Survival (OS) was defined as time from randomization to death due to any cause, regardless of whether the event occurred on or off study drug (depatuxizumab mafodotin/temozolomide/lomustine). (NCT02343406)
Timeframe: From the date of randomization up to the date of participant's death; participants who completed treatment were to be assessed every 12 weeks, up to 28 months.

,,
Interventionmonths (Number)
25th quartile50th quartile75th quartile
ABT-414_adult4.67.915.5
ABT-414/Temozolomide5.79.616.9
Control (Temozolomide/Lomustine)4.98.212.6

Adult Study: Overall Survival in the Subgroup With Epidermal Growth Factor Receptor (EGFRvIII) Mutation

Overall Survival (OS) was defined as time from randomization to death due to any cause, regardless of whether the event occurred on or off study drug (depatuxizumab mafodotin/temozolomide/lomustine) for all randomized participants that had the Epidermal Growth Factor Receptor (EGFRvIII) mutation. (NCT02343406)
Timeframe: From the date of randomization up to the date of participant's death; participants who completed treatment were to be assessed every 12 weeks, up to 28 months

,,
Interventionmonths (Number)
25th quartile50th quartile75th quartile
ABT-414_adult5.08.413.9
ABT-414/Temozolomide6.39.414.4
Control (Temozolomide/Lomustine)4.77.512.4

Adult Study: Progression-Free Survival (PFS)

Progression-free survival was assessed per response assessment in neuro-oncology criteria (RANO) criteria and assessed by an independent review committee and was defined as the length of time during and after the treatment of a disease, that the participant lived with the disease but did not get worse. (NCT02343406)
Timeframe: Measured every 8 weeks from date of randomization until the date of first objective progression or subject's death, whichever occurred first, up to 2 years

,,
Interventionmonths (Number)
25th quartile50th quartile75th quartile
ABT-414_adult1.51.93.5
ABT-414/Temozolomide1.82.74.9
Control (Temozolomide/Lomustine)1.61.94.2

Apparent Volume of Distribution (Vd/F) for Veliparib [Pharmacokinetic Parameter]

During course 1, blood samples were collected pre-veliparib on day 1, at 0.5, 1, 2, and 6-8 hours after the first dose, pre-veliparib on day 4 (steady state), and 2 hours after the morning dose. Veliparib concentrations were measured using a liquid chromatography tandem mass spectrometry assay and pharmacokinetic parameters were evaluated using a non-compartmental analysis. (NCT01514201)
Timeframe: Up to day 4

InterventionL/m^2 (Mean)
Phase I, Dose Level 1 (50 mg)75.4
Phase I, Dose Level 2 (65 mg)56.1
Phase I, Dose Level 3 (85 mg)63.9
Phase II (MTD)73.1

Maximum Concentration of Veliparib (Cmax) on Day 1 (Measured in μM) [Pharmacokinetic Parameter]

During course 1, blood samples were collected pre-veliparib on day 1, at 0.5, 1, 2, and 6-8 hours after the first dose, pre-veliparib on day 4 (steady state), and 2 hours after the morning dose. Veliparib concentrations were measured using a liquid chromatography tandem mass spectrometry assay and pharmacokinetic parameters were evaluated using a non-compartmental analysis. Cmax measures the highest concentration of drug. (NCT01514201)
Timeframe: Day 1

InterventionμM (Mean)
Phase I, Dose Level 1 (50 mg)2.12
Phase I, Dose Level 2 (65 mg)3.45
Phase I, Dose Level 3 (85 mg)4.40
Phase II (MTD)3.45

Maximum-tolerated Dose of Veliparib Defined as Highest Dose Level With Fewer Than 2 Dose Limiting Toxicities in 6 Patients as Assessed by the National Cancer Institute Common Terminology Criteria for Adverse Events Version 4.0 (Phase I)

The traditional 3+3 dose finding algorithm was used to estimate the maximum-tolerated dose of veliparib given concurrently with radiation therapy. The dose-limiting toxicity observation period was the first 10 weeks of therapy. Dose-limiting toxicities included any grade 4 non-hematologic toxicity, any grade 3 non-hematologic toxicity with a few exceptions (see section 5.2.1.2 of the protocol document), any grade 2 non-hematologic toxicity that persisted for >7 days and considered medically significant that required treatment interruption; grade 3 or higher thrombocytopenia or grade 4 neutropenia; and any Veliparib related adverse event that led to a dose reduction or the permanent cessation of therapy. (NCT01514201)
Timeframe: 10 weeks

Interventionmg/m2/dose BID (Number)
Phase I Patients65

Mean Apparent Clearance (CL/F) for Veliparib [Pharmacokinetic Parameter]

During course 1, blood samples were collected pre-veliparib on day 1, at 0.5, 1, 2, and 6-8 hours after the first dose, pre-veliparib on day 4 (steady state), and 2 hours after the morning dose. Veliparib concentrations were measured using a liquid chromatography tandem mass spectrometry assay and pharmacokinetic parameters were evaluated using a non-compartmental analysis. (NCT01514201)
Timeframe: Up to day 4

InterventionL/m^2/h (Mean)
Phase I, Dose Level 1 (50 mg)16.1
Phase I, Dose Level 2 (65 mg)13.2
Phase I, Dose Level 3 (85 mg)15.8
Phase II (MTD)11.7

Number of Phase I Patients Who Experienced Dose Limiting Toxicities (DLTs)

DLTs were defined as any of the following adverse events that were at least possibly attributable to Veliparib observed during the dose finding phase (the first 10 weeks of therapy). Hematologic dose limiting toxicities included grade 3 and higher thrombocytopenia or grade 4 neutropenia. Non-hematologic dose limiting toxicities included any grade 4 non-hematologic toxicity, any grade 3 non-hematologic toxicity with some exceptions (e.g., nausea and vomiting of <5 days; fever or infection of <5 days; hypophosphatemia, hypokalemia, hypocalcemia or hypomagnesemia responsive to oral supplementation; elevation of transaminases that return to levels meeting eligibility criteria within 7 days), or any grade non-hematologic toxicity that persisted for >7 days and considered medically significant or sufficiently intolerable by patients that required treatment interruption. (NCT01514201)
Timeframe: 10 weeks

InterventionParticipants (Count of Participants)
Phase I, Dose Level 1 (50 mg)1
Phase I, Dose Level 2 (65 mg)0
Phase I, Dose Level 3 (85 mg)3

Overall Survival

Overall survival was defined as the interval from date on treatment to date of death from any cause or to date of last follow-up. Patients who had not failed (died) at the time of analyses were censored at their last date of contact. The method of Kaplan and Meier was used to estimate overall survival. The 3-year estimate with a 95% confidence interval is reported. (NCT01514201)
Timeframe: Time from initiation of therapy to the date of death from any cause or to the date patient was known to be alive for surviving patients, assessed to up to 3 years

InterventionPercent probability (Number)
Phase II Patients + Phase I MTD Patients5.3

Percentage of Participants Observed to Have Unacceptable Toxicity During the Intra-patient Dose Escalation of Temozolomide During Maintenance Therapy (Feasibility Analysis Population)

Unacceptable toxicities during maintenance included events at least possibly attributable to Veliparib and temozolomide (TMZ) such as any grade 4 non-hematologic toxicity, any grade 3 non-hematologic toxicity with some exceptions (e.g., grade 3 nausea/vomiting <5 days, grade 3 fever or infection <5 days), grade 3+ thrombocytopenia, grade 4 neutropenia, delay >14 days in starting subsequent cycle due to neutrophil <1,000/mm3 or platelet <100,000/mm3. Maintenance therapy was initiated with 25 mg/m2 Veliparib and 135 mg/m2 of TMZ, with the possibility to escalate TMZ to 175 mg/m2 and 200 mg/m2 in courses 2 and 3, respectively, if no unacceptable toxicities occurred following one course of treatment at each of the dose levels to be tested. Intra-patient dose escalation to a given dose (135, 175, or 200 mg/m2) was halted based on rules employed in 3+3 designs. This dose escalation was intended for all patients but was halted early, during the phase I portion, as it was not well tolerated. (NCT01514201)
Timeframe: 28 days per treatment cycle

Intervention% of participants (Number)
Dose Level 1 (135 mg/m2)9
Dose Level 2 (175 mg/m2)40
Dose Level 3 (200 mg/m2)67

Percentage of Participants With Significant Changes in Poly(ADP-ribose) Polymerase (PARP) Levels Post-Veliparib, as Measured in Peripheral Blood Monocytes (PBMCs)

Blood samples were collected from patients and assessed pre- and post-Veliparib to assess treatment-induced changes. A significant change in PBMC PARP level was arbitrarily defined as a >50% increase or decrease from the pre-treatment level, documented at week 6 and/or week 11 after starting protocol therapy. (NCT01514201)
Timeframe: Baseline and up to 11 weeks

Interventionpercentage of participants (Number)
Phase I, Dose Level 1 (50 mg)100
Phase I, Dose Level 2 (65 mg)100
Phase I, Dose Level 3 (85 mg)75
Phase II (MTD)36

Percentage of Patients With Pseudo Progression

For participants that showed possible tumor progression (pseudo progression) on magnetic resonance imaging (MRI) during the first 6 months of therapy, treating physicians had the option of allowing patients to remain on therapy and repeating the disease assessment in 4-6 weeks. If the repeat MRI at 4-6 weeks showed disease progression, the patient was noted to have true disease progression (and the progression date corresponded to that of the first MRI). If the repeat MRI at 4-6 weeks did not show disease progression, then the patient was noted to have pseudo progression. The percentage of patients observed to have experienced pseudo progression was provided with a 95% confidence interval. (NCT01514201)
Timeframe: Up to 6 months

InterventionPercentage of participants (Number)
Phase I, Dose Level 1 (50 mg)33.3
Phase I, Dose Level 2 (65 mg)16.7
Phase I, Dose Level 3 (85 mg)0
Phase II (MTD)12.8

Progression-free Survival (PFS)

PFS was defined as the interval from date of treatment initiation to date of first event (disease progression or relapse, second malignancy or death from any cause). Patients who had not failed at the time of analyses were censored at their last date of contact. The method of Kaplan and Meier was used to estimate PFS. A 3-year estimate with a 95% confidence interval is reported. (NCT01514201)
Timeframe: Time from initiation of treatment to the earliest date of failure (disease progression, death from any cause, or second malignancy), assessed up to 3 years

InterventionPercent probability (Number)
Phase II Patients + Phase I MTD Patients2.9

Terminal Half-life (t1/2) for Veliparib [Pharmacokinetic Parameter]

During course 1, blood samples were collected pre-veliparib on day 1, at 0.5, 1, 2, and 6-8 hours after the first dose, pre-veliparib on day 4 (steady state), and 2 hours after the morning dose. Veliparib concentrations were measured using a liquid chromatography tandem mass spectrometry assay and pharmacokinetic parameters were evaluated using a non-compartmental analysis. (NCT01514201)
Timeframe: Up to day 4

InterventionHour (Mean)
Phase I, Dose Level 1 (50 mg)5.18
Phase I, Dose Level 2 (65 mg)2.62
Phase I, Dose Level 3 (85 mg)4.45
Phase II (MTD)2.18

Trough for Veliparib [Pharmacokinetic Parameter]

During course 1, blood samples were collected pre-veliparib on day 1, at 0.5, 1, 2, and 6-8 hours after the first dose, pre-veliparib on day 4 (steady state), and 2 hours after the morning dose. Veliparib concentrations were measured using a liquid chromatography tandem mass spectrometry assay and pharmacokinetic parameters were evaluated using a non-compartmental analysis. (NCT01514201)
Timeframe: Up to day 4

Interventionng/mL (Mean)
Phase I, Dose Level 1 (50 mg)58
Phase I, Dose Level 2 (65 mg)140
Phase I, Dose Level 3 (85 mg)163
Phase II (MTD)84

Levels of Urinary Biomarkers

Urine samples were analyzed for a panel of biomarkers. Netrin-1 levels were determined by ELISA. Levels of matrix metalloproteinase 3 (MMP3) and basic fibroblast growth factor (bFGF) were analyzed using custom Luminex® screening assays. Tissue inhibitor of metalloproteinase 1 (TIMP1) levels were analyzed using a Luminex® performance assay. Protein concentrations are given in picograms per microgram (pg/μg), and were determined by dividing the concentration of the target protein in the sample (pg/mL) by the concentration of total protein in the sample (μg/mL) as a normalization measure. (NCT01514201)
Timeframe: Baseline to up to 3 years

,,,
Interventionpg/μg (Median)
MMP3 at pre-studyMMP3 at week 10-11MMP3 at week 18MMP3 at week 26Netrin-1 at pre-studyNetrin-1 at week 10-11Netrin-1 at week 18Netrin-1 at week 26TIMP1 at pre-studyTIMP1 at week 10-11TIMP1 at week 18TIMP1 at week 26bFGF at pre-studybFGF at week 10-11bFGF at week 18bFGF at week 26
Phase I, Dose Level 1 (50 mg)2.01.44.32.90.10.10.30.43.46.210.77.33.13.610.37.7
Phase I, Dose Level 2 (65 mg)1.01.01.70.40.10.10.10.29.911.97.75.21.92.13.50.9
Phase I, Dose Level 3 (85 mg)0.00.80.71.00.10.10.00.010.812.314.832.81.21.81.31.1
Phase II (MTD)1.12.62.33.00.10.00.10.07.37.57.110.74.53.54.44.5

Maximum Concentration of Veliparib (Cmax) on Days 1 and 4 (Measured in ng/mL) [Pharmacokinetic Parameter]

During course 1, blood samples were collected pre-veliparib on day 1, at 0.5, 1, 2, and 6-8 hours after the first dose, pre-veliparib on day 4 (steady state), and 2 hours after the morning dose. Veliparib concentrations were measured using a liquid chromatography tandem mass spectrometry assay and pharmacokinetic parameters were evaluated using a non-compartmental analysis. Cmax measures the highest concentration of drug. (NCT01514201)
Timeframe: Up to day 4

,,,
Interventionng/mL (Mean)
Day 1, Cmax (ng/mL)Day 4, Cmax (ng/mL)
Phase I, Dose Level 1 (50 mg)519409
Phase I, Dose Level 2 (65 mg)843788
Phase I, Dose Level 3 (85 mg)1074954
Phase II (MTD)844717

Median Overall Survival (OS) by Arm and MGMT Methylation Status

Median OS depending on treatment arm in patients with methylated MGMT (NCT02209948)
Timeframe: Through the whole study. 4 years. The median follow up for each patient was 33.4 months

Interventionmonths (Median)
Temozolomide20.7
Without Treatment27.1

Median Progression-free Survival (PFS) by Arm and MGMT Methylation Status

Median Progression Free Survival depending on treatment arm in patients with MGMT methylation (NCT02209948)
Timeframe: Through the whole study. 4 years. The median follow up for each patient was 33.4 months

Interventionmonths (Median)
Temozolomide11.4
Without Treatment8.5

Overall Survival

Time between start of treatment and death (NCT02209948)
Timeframe: Through the whole study. 4 years. The median follow up for each patient was 33.4 months

Interventionmonths (Median)
Temozolomide18.2
Without Treatment23.3

Progresion Free Survival Median Values

It will be measured following Response assessment in neuro-oncology (RANO) guidelines: progression-free survival (NCT02209948)
Timeframe: Through the whole study. 4 years. The median follow up for each patient was 33.4 months

Interventionmonths (Median)
Temozolomide9.5
Without Treatment7.77

Progression Free Survival at 6 Month

"Percentage of patients without progression of disease and time between start of treatment and progression of disease.~The progression disease is defined as the time from the date of randomization to the date of progression defined according to the RANO criteria." (NCT02209948)
Timeframe: 6 month

Interventionpercentage of patients (Number)
Temozolomide61.3
Without Treatment55.7

Number of Participants With Adverse Effects

Total number of patients presenting adverse events, stratified by type of event and grade. Adverse Events of special interest: Only relevant differences in toxicity by arm. (NCT02209948)
Timeframe: Through the whole study. 4 years

InterventionParticipants (Count of Participants)
Lymphopenia72025836Lymphopenia72025835Thrombocytopenia72025835Thrombocytopenia72025836Nausea and vomiting72025835Nausea and vomiting72025836Fatigue72025836Fatigue72025835Leucopenia72025835Leucopenia72025836
Grade 1-2Grade 3-4not affected
Temozolomide52
Without Treatment33
Temozolomide3
Temozolomide25
Without Treatment46
Temozolomide36
Without Treatment17
Temozolomide2
Temozolomide42
Without Treatment62
Temozolomide30
Without Treatment10
Without Treatment0
Temozolomide50
Without Treatment69
Temozolomide35
Without Treatment21
Temozolomide0
Temozolomide45
Without Treatment58
Temozolomide29
Without Treatment20
Temozolomide1
Without Treatment59

Objective Response Rate (ORR) for Cohort 2

"ORR was measured by the percentage of participants whose best overall response (BOR) is confirmed Complete Response (CR) or Partial Response (PR) divided by response evaluable participants. The best overall response (BOR) is determined once all the data for the participant is known. BOR is defined as the best response designation, as determined by investigators, recorded between the date of randomization and the date of objectively documented progression per RANO criteria, the date of subsequent therapy, or date of surgical resection, whichever occurs first.~Confidence interval based on the Clopper and Pearson method. For the comparison of the odds ratio of Nivolumab over Bevacizumab, the Cochran-Mantel-Haenszel (CMH) method of weighting was utilized." (NCT02017717)
Timeframe: Time from randomization to the date of the first documented tumor progression or death due to any cause (up to approximately 31 months)

InterventionPercentage of participants (Number)
Cohort 2: Arm N37.8
Cohort 2: Arm B23.1

Overall Survival (OS) at 12 Months for Cohort 2

OS(12) is measured as the percentage of participants alive at 12 months per Kaplan-Meier curve of OS. Z test with variance estimation based on Greenwood formula using log(-log) transformation. (NCT02017717)
Timeframe: From randomization to 12 months following randomization

InterventionPercentage of Participants (Number)
Cohort 2: Arm N341.8
Cohort 2: Arm B42.4

Overall Survival (OS) for Cohort 2

"OS was measured in months from the time of randomization to the event date (death) due to any cause. A participant who has not died will be censored at the last known alive date.~Based on Kaplan-Meier Estimates. Hazard ratio from Cox proportional hazard model stratified by presence of measurable lesions at baseline per IVRS. P-value from log-rank test stratified by presence of measurable lesions at baseline per IVRS." (NCT02017717)
Timeframe: Time between the date of randomization and the date of death due to any cause (up to 17Jun2019, approximately 5 years)

InterventionMonths (Median)
Cohort 2: Arm N39.77
Cohort 2: Arm B10.05

Overall Survival (OS) for Cohorts 1c and 1d

"OS was measured in months from the time of randomization (Part B) or time of treatment (Part A) to the event date (death) due to any cause. A participant who has not died will be censored at the last known alive date.~Based on Kaplan-Meier Estimates." (NCT02017717)
Timeframe: Time between the date of randomization and the date of death due to any cause (up to 17Jun2019, approximately 5 years)

InterventionMonths (Median)
Part A Cohort 1c: Arm N3+RT+TMZ22.08
Part A Cohort 1d: Arm N3+RT14.41
Part B Cohort 1c: Arm N3+RT+TMZ15.95
Part B Cohort 1d: Arm N3+RT13.96

Progression Free Survival (PFS) for Cohort 2

PFS was measured in months from the time of randomization to the date of the first documented tumor progression or death due to any cause. Based on Kaplan-Meier Estimates. Hazard ratio from Cox proportional hazard model stratified by presence of measurable lesions at baseline per IVRS. (NCT02017717)
Timeframe: Time from randomization to the date of the first documented tumor progression or death due to any cause (up to 17Jun2019, approximately 5 years)

InterventionMonths (Median)
Cohort 2: Arm N31.51
Cohort 2: Arm B3.61

Percentage of Participants With Adverse Events (Worst Grade) in Cohorts 1, 1b, 1c and 1d

The percentage of participants who experienced an adverse event by worst grade in each treatment arm. Toxicities were graded using the National Cancer Institute (NCI) Common Terminology Criteria for Adverse Events (CTCAE) version 4.0. MedDRA Version: 24.1 (NCT02017717)
Timeframe: From first dose to 30 days post last dose (up to approximately 34 months).

,,,,,,
InterventionPercentage of participants (Number)
Grade 1Grade 2Grade 3Grade 4Grade 5
Cohort 1: Arm N1+I3010.070.020.00
Cohort 1: Arm N320.030.040.010.00
Cohort 1b: Arm N3+I15.025.050.020.00
Part A Cohort 1c: Arm N3+RT+TMZ6.512.958.122.60
Part A Cohort 1d: Arm N3+RT13.326.733.320.03.3
Part B Cohort 1c: Arm N3+RT+TMZ3.628.650.010.73.6
Part B Cohort 1d: Arm N3+RT17.925.035.721.40

Percentage of Participants With Drug-Related Adverse Events Leading to Discontinuation by Worst CTC Grade for All Treated Participants in Cohorts 1, 1b, 1c and 1d Who Permanently Discontinued Study Medication Prior to Completing Four Doses

The percentage of participants who experienced a drug-related adverse event leading to drug discontinuation by worst grade (grade 5 being the worst) prior to complete four-dose treatment. Toxicities were graded using the National Cancer Institute (NCI) Common Terminology Criteria for Adverse Events (CTCAE) version 4.0. MedDRA Version: 24.1 (NCT02017717)
Timeframe: Includes events reported between first dose and 30 days after last dose of study therapy (up to 3 doses, up to approximately 2 months)

,,,,,,
InterventionPercentage of participants (Number)
Grade 1Grade 2Grade 3Grade 4Grade 5
Cohort 1: Arm N1+I30016.733.30
Cohort 1: Arm N300000
Cohort 1b: Arm N3+I100000
Part A Cohort 1c: Arm N3+RT+TMZ0066.700
Part A Cohort 1d: Arm N3+RT00000
Part B Cohort 1c: Arm N3+RT+TMZ00000
Part B Cohort 1d: Arm N3+RT0050.000

Percentage of Participants With Serious Adverse Events (Worst Grade) in Cohorts 1, 1b, 1c and 1d

The percentage of participants who experienced a serious adverse event by worst grade in each treatment arm. Toxicities were graded using the National Cancer Institute (NCI) Common Terminology Criteria for Adverse Events (CTCAE) version 4.0. MedDRA Version: 24.1 (NCT02017717)
Timeframe: From first dose to 30 days post last dose (up to approximately 34 months).

,,,,,,
InterventionPercentage of participants (Number)
Grade 1Grade 2Grade 3Grade 4Grade 5
Cohort 1: Arm N1+I30060.020.00
Cohort 1: Arm N3010.040.000
Cohort 1b: Arm N3+I105.035.015.00
Part A Cohort 1c: Arm N3+RT+TMZ3.2045.216.10
Part A Cohort 1d: Arm N3+RT016.716.716.73.3
Part B Cohort 1c: Arm N3+RT+TMZ03.635.73.63.6
Part B Cohort 1d: Arm N3+RT010.732.114.30

Percentage of Participants With Specific Laboratory Abnormalities in Liver Tests in Cohorts 1, 1b, 1c and 1d

"The percentage of participants who experienced a laboratory abnormality of the liver in each treatment arm.~MedDRA Version: 24.1~Aspartate aminotransferase (AST) Alanine aminotransferase (ALT) Upper Limit of Normal (ULN) Denominator corresponds to participants with at least on one treatment measurement of the corresponding laboratory parameter. Includes laboratory results reported after the first dose and within 30 days of last dose of study therapy." (NCT02017717)
Timeframe: From first dose to 30 days post last dose (up to approximately 34 months).

,,,,,,
InterventionPercentage of participants (Number)
ALT OR AST > 3*ULNALT OR AST > 5*ULNALT OR AST > 10*ULNALT OR AST > 20*ULNTOTAL BILIRUBIN (Tbili) > 2*ULNALP > 1.5*ULNALT or AST > 3xULN w/ Tbili > 1.5*ULN within 1 dayALT or AST > 3*ULN w/ Tbili > 1.5*ULN within 30 daysALT or AST > 3xULN w/ Tbili > 2*ULN within 1 dayALT or AST > 3*ULN w/ Tbili > 2*ULN within 30 days
Cohort 1: Arm N1+I330.020.010.010.010.010.010.010.010.010.0
Cohort 1: Arm N30.00.00.00.00.010.00.00.00.00.0
Cohort 1b: Arm N3+I115.810.55.35.30.00.00.00.00.00.0
Part A Cohort 1c: Arm N3+RT+TMZ22.612.96.53.20.00.00.00.00.00.0
Part A Cohort 1d: Arm N3+RT10.03.33.33.30.03.30.00.00.00.0
Part B Cohort 1c: Arm N3+RT+TMZ18.511.13.70.07.40.03.73.73.73.7
Part B Cohort 1d: Arm N3+RT14.83.73.73.70.03.70.00.00.00.0

Percentage of Participants With Specific Laboratory Abnormalities in Thyroid Tests in Cohorts 1, 1b, 1c and 1d

"The percentage of participants who experienced a laboratory abnormality of the thyroid in each treatment arm.~MedDRA Version: 24.1~Free T3 (FT3) Free T4 (FT4) Lower Limit of Normal (LLN)~(A) Within a 2-week window after the abnormal TSH test date. (B) Includes participants with TSH abnormality and with no FT3/FT4 test values in the 2-week window or with non-abnormal value(s) from only one of the two tests and no value from the other test." (NCT02017717)
Timeframe: From first dose to 30 days post last dose (up to approximately 34 months).

,,,,,,
InterventionPercentage of participants (Number)
TSH > ULNTSH > ULN, WITH TSH <= ULN AT BASELINETSH > ULN, WITH AT LEAST ONE FT3/FT4 TEST < LLNTSH > ULN, WITH ALL OTHER FT3/FT4 TEST >= LLNTSH > ULN, WITH FT3/FT4 TEST MISSINGTSH < LLNTSH < LLN, WITH TSH >= LLN AT BASELINETSHULNTSH < LLN, WITH ALL OTHER FT3/FT4 TEST <= ULNTSH < LLN, WITH FT3/FT4 TEST MISSING
Cohort 1: Arm N1+I320.020.020.00.00.060.060.030.020.010.0
Cohort 1: Arm N350.030.030.010.010.030.030.010.020.00.0
Cohort 1b: Arm N3+I110.510.510.50.00.031.631.615.810.55.3
Part A Cohort 1c: Arm N3+RT+TMZ23.320.013.36.73.343.333.310.030.03.3
Part A Cohort 1d: Arm N3+RT16.716.713.30.03.340.040.013.316.710.0
Part B Cohort 1c: Arm N3+RT+TMZ11.111.17.43.70.022.218.511.111.10.0
Part B Cohort 1d: Arm N3+RT7.47.40.07.40.033.318.50.029.63.7

Methylation Status of the O6-methylguanine-DNA Methyltransferase Promoter

Overall survival for patients by Methylation status of the O6-methylguanine-DNA methyltransferase promoter (NCT00482677)
Timeframe: 7 years

InterventionMonths (Median)
Temozolomide13.47
Radiation7.69

Overall Survival

Time from date of randomization to the date of death of any causes, or censored at last known alive date. (NCT00482677)
Timeframe: 7 years

InterventionMonths (Median)
Temozolomide9.33
Radiation7.62

Progression-free Survival

Time from date of randomization to the date of disease progression or death whichever came first, or censored at last disease assessment date. (NCT00482677)
Timeframe: 7 years

InterventionMonths (Median)
Temozolomide5.29
Radiation3.94

Determination of Maximum Tolerated Dose (MTD)

To evaluate the maximum tolerated dose of nanoliposomal irinotecan with continuous low-dose temozolomide for patients with recurrent glioblastoma. (NCT03119064)
Timeframe: Every two weeks for 4 weeks

Interventionmg/m^2 (Number)
All Participants50

Response

"Per Response Evaluation Criteria In Solid Tumors Criteria (RECIST v1.0) for target lesions and assessed by MRI: Complete Response (CR), Disappearance of all target lesions; Partial Response (PR), >=30% decrease in the sum of the longest diameter of target lesions; Overall Response (OR) = CR + PR." (NCT03119064)
Timeframe: Every 2 months on study treatment then very 3 months once treatment has stopped, until progression of disease up to 2 years.

,
Interventionparticipants (Number)
Partial ResponseProgressive Disease
Dose 118
Dose 212

Toxicities

Treatment emergent toxicities of nanoliposomal irinotecan with continuous low-dose temozolomide using CTCAE version 4.03, grades 2 through 4 (NCT03119064)
Timeframe: Baseline through 30 days post off study treatment

,
Interventionevents (Number)
NeutropeniaALT/ASTHypokalemiaHypophosphatemiaNauseaFatigueDiarrheaAnorexiaDehydrationUrticaria
Dose 10211120001
Dose 21110222220

Proportion of Grade IV MGMT Un-methylated Patients That Experience Confirmed-progression-free Survival at 6 Months (CPFS6)

"The proportion of Grade IV MGMT un-methylated patients that experience confirmed-progression-free survival at 6 months (CPFS6). Progression is defined by any of the following:~≥25% increase in the sum of products of perpendicular diameters of enhancing lesions compared to the smallest tumor measurement obtained either at baseline or best response, on stable or increasing doses of corticosteroids~Significant increase in T2/FLAIR non-enhancing lesion on stable or increasing doses of corticosteroids compared to baseline scan or best response following initiation of therapy, not due to co-morbid events~Any new lesion~Clear clinical deterioration not attributable to other causes apart from the tumor or changes in corticosteroid dose.~Failure to return for evaluation due to death or deteriorating condition~Clear progression of non-measurable disease" (NCT01991977)
Timeframe: Time from registration to the confirmed disease progression, assessed at 6 months

Interventionproportion of participants (Number)
Diagnostic (PET, pMRI, DTI, IMRT, Temozolomide)0.795

Number of Participants Evaluated for Toxicities

(NCT00588523)
Timeframe: up to 2 years

InterventionParticipants (Count of Participants)
Participants With Newly Diagnosed Anaplastic Oligodendroglioma60

Progession Free Survival

To determine the duration of disease control of newly diagnosed pure and mixed anaplastic oligodendrogliomas treated with dose-intensive chemotherapy requiring hematopoietic stem cell support. (NCT00588523)
Timeframe: 2 years

Intervention% of participants without progression (Number)
Participants With Newly Diagnosed Anaplastic Oligodendroglioma85.7

Deterioration Free Survival in M.D. Anderson Symptom Inventory Brain Tumor Module (MDASI-BT) Symptom Severity Score

The MDASI-BT assesses the severity of multiple brain tumor-related symptoms and the impact of these symptoms on daily functioning in the last 24 hours. It consists of 22 symptom items and 6 interference items, each rated from 0 to 10. MDASI-BT symptom severity score is defined as average over 13 core symptom items and 9 brain tumor symptom items, with a total score of 0 to 10, with higher score indicating worse symptoms/interference. Changes in symptom severity score were classified into 3 categories: improved (≤ -1), stable (> -1 and < 1), and deteriorated (≥ 1). Deterioration is defined as satisfying the deterioration criteria (i.e., increase in symptom severity score by ≥ 1 unit) without further improvement (i.e., failing to satisfy deterioration criteria) within 8 weeks or occurrence of death. (NCT02573324)
Timeframe: Overall median duration of follow-up was 15.5 months (range: 0.1, 35.6).

Interventionmonths (Median)
Placebo, Radiation and TMZ11.0
Depatuxizumab Mafodotin, Radiation and TMZ6.1

Deterioration Free Survival in MDASI-BT Symptom Interference Score

The MDASI-BT assesses the severity of multiple brain tumor-related symptoms and the impact of these symptoms on daily functioning in the last 24 hours. It consists of 22 symptom items and 6 interference items, each rated from 0 to 10. MDASI-BT symptom interference score is defined as an average of 6 interference items, with a total score of 0 to 10, where higher scores indicate worse interference. Changes in symptom interference score were classified into 3 categories: improved (≤ -1), stable (> -1 and < 1), and deteriorated (≥ 1). Deterioration is defined as satisfying the deterioration criteria (i.e., increase in symptom interference score by ≥ 1 unit) without further improvement (i.e., failing to satisfy deterioration criteria) within 8 weeks or occurrence of death. (NCT02573324)
Timeframe: Overall median duration of follow-up was 15.5 months (range: 0.1, 35.6).

Interventionmonths (Median)
Placebo, Radiation and TMZ9.7
Depatuxizumab Mafodotin, Radiation and TMZ6.1

Deterioration Free Survival in Neurocognitive Functioning on the Hopkins Verbal Learning Test Revised (HVLT-R) Total Recall Score

The HVLT-R consists of 3 parts. Free call has a range of 0 to 36, delayed recall has a range from 0 to 12, and delayed recognition has a range of -12 to 12. Higher scores indicating better function in all 3 parts. When scoring the HVLT-R, the 3 learning trials are combined to calculate a total recall score (range -12 to 60). Deterioration is defined as satisfying the deterioration criteria (i.e., decrease in HVLT-R total recall score by 5 units) without further improvement within 8 weeks or occurrence of death. (NCT02573324)
Timeframe: Overall median duration of follow-up was 15.5 months (range: 0.1, 35.6).

Interventionmonths (Median)
Placebo, Radiation and TMZ13.2
Depatuxizumab Mafodotin, Radiation and TMZ10.7

OS for the Epidermal Growth Factor Receptor (EGFR)vIII-Mutated Tumor Subgroup

Time to OS is defined as the number of days from the date of randomization to the date of death due to any cause. (NCT02573324)
Timeframe: Overall median duration of follow-up was 15.5 months (range: 0.1, 35.6).

Interventionmonths (Median)
Placebo, Radiation and TMZ18.2
Depatuxizumab Mafodotin, Radiation and TMZ19.8

OS for the MGMT Methylated Group

Time to OS is defined as the number of days from the date of randomization to the date of death due to any cause. (NCT02573324)
Timeframe: Overall median duration of follow-up was 15.5 months (range: 0.1, 35.6).

Interventionmonths (Median)
Placebo, Radiation and TMZNA
Depatuxizumab Mafodotin, Radiation and TMZ25.4

OS for the O6-methylguaninemethlytransferese (MGMT) Unmethylated Group

"Time to OS is defined as the number of days from the date of randomization to the date of death due to any cause.~Unmethylated MGMT promoter is associated with a worse prognosis in GBM" (NCT02573324)
Timeframe: Overall median duration of follow-up was 15.5 months (range: 0.1, 35.6).

Interventionmonths (Median)
Placebo, Radiation and TMZ16.2
Depatuxizumab Mafodotin, Radiation and TMZ16.1

Overall Survival (OS)

Time to OS is defined as the number of days from the date of randomization to the date of death due to any cause. (NCT02573324)
Timeframe: Overall median duration of follow-up was 15.5 months (range: 0.1, 35.6).

Interventionmonths (Median)
Placebo, Radiation and TMZ18.7
Depatuxizumab Mafodotin, Radiation and TMZ18.9

PFS for EGFRvIII-Mutated Tumor Subgroup

PFS will be defined as the number of days from the date of randomization to the date of earliest disease progression based on Response Assessment in Neuro-Oncology (RANO) criteria or to the date of death, if disease progression does not occur. (NCT02573324)
Timeframe: Overall median duration of follow-up was 15.5 months (range: 0.1, 35.6).

Interventionmonths (Median)
Placebo, Radiation and TMZ5.9
Depatuxizumab Mafodotin, Radiation and TMZ8.3

Progression-Free Survival (PFS)

PFS will be defined as the number of days from the date of randomization to the date of earliest disease progression based on Response Assessment in Neuro-Oncology (RANO) criteria (see Wen et al. J Clin Oncol. 2010 Apr 10;28(11):1963-72) or to the date of death, if disease progression does not occur. (NCT02573324)
Timeframe: Overall median duration of follow-up was 15.5 months (range: 0.1, 35.6).

Interventionmonths (Median)
Placebo, Radiation and TMZ6.3
Depatuxizumab Mafodotin, Radiation and TMZ8.0

Change From Baseline for Karnofsky Performance Status (KPS) Score at Baseline, Post-Baseline (up to Month 30)

KPS is an 11-level score (0, 10, 20, 30, 40, 50, 60, 70, 80, 90, and 100) which ranges between 0 (death) to 100 (complete healthy status); a higher score represents a higher ability to perform daily tasks. Deterioration in KPS was defined as decrease of 20 or more points in KPS score. (NCT00967330)
Timeframe: Baseline, Post-Baseline (up to Month 30)

Interventionunits on a scale (Least Squares Mean)
Bevacizumab + Irinotecan-3.3399
Temozolomide-5.4909

Overall Survival (OS)

Overall survival was defined as the time from randomization to death from any cause. OS was estimated using Kaplan-Meier method. (NCT00967330)
Timeframe: From baseline until death (up to 4.5 years)

InterventionMonths (Median)
Bevacizumab + Irinotecan16.64
Temozolomide17.30

Percentage of Participants Achieving Progression-Free Survival (PFS) Without Disease Progression or Death at 6 Months

Progression-free survival was defined as the time from randomization to objective tumor progression or death from any cause, whichever came first. Progression was defined as 25 percent (%) increase in size of enhancing tumor or any new tumor on gadolinium contrast agent magnetic resonance imaging (Gd-MRI) scans, or neurologically worse, and steroids stable or increased. Percentage of participants achieving PFS without disease progression or death was reported. (NCT00967330)
Timeframe: 6 months

Interventionpercentage of participants (Number)
Bevacizumab + Irinotecan79.31
Temozolomide42.59

Percentage of Participants Who Received Corticosteroid for Glioblastoma

Participants used corticosteroids for the glioblastoma condition. Corticosteroids included dexamethasone, methylprednisone, fortecortin, hydrocortisone, urbason, and prednisolone. (NCT00967330)
Timeframe: From baseline to Month 6

Interventionpercentage of participants (Number)
Bevacizumab + Irinotecan80.0
Temozolomide78.7

Progression-Free Survival (PFS)

Progression-free survival was defined as the time from randomization to objective tumor progression or death from any cause, whichever came first. Progression was defined as 25% increase in size of enhancing tumor or any new tumor on Gd-MRI scans, or neurologically worse, and steroids stable or increased. PFS was estimated using Kaplan-Meier method. (NCT00967330)
Timeframe: From baseline to the end of the study (up to 4.5 years)

InterventionMonths (Median)
Bevacizumab + Irinotecan9.74
Temozolomide5.99

Time to Treatment Failure

(NCT00967330)
Timeframe: From baseline until end of study (up to 4.5 years)

Interventionyears (Median)
Bevacizumab + IrinotecanNA
TemozolomideNA

Change From Baseline for EORTC QLQ Brain Neoplasm 20 (BN20) at Baseline, Post-Baseline (up to Month 30)

EORTC QLQ-BN20 consisted of 20 items assessing visual disorders, motor dysfunction, communication deficit, various disease symptoms (e.g. headaches and seizures), treatment toxicities (e.g. hair loss) and future uncertainty. All of the 20 items are rated on a 4 point Likert scale from 1=not at all, 2=a little, 3=quite a bit and 4=very much, and were linearly transformed to a 0-100 scale, with higher scores indicating more severe symptoms. (NCT00967330)
Timeframe: Baseline, Post-Baseline (up to Month 30)

,
Interventionunits on a scale (Least Squares Mean)
Future uncertaintyVisual disorderMotor dysfunctionCommunication deficitHeadachesDrowsinesHair lossItchy skinWeakness of legsBladder control
Bevacizumab + Irinotecan-5.2779-2.08695.44164.74404.390511.720411.92355.48828.95861.5020
Temozolomide-8.5478-3.2026.54294.6431-3.93898.28057.33286.46907.92451.9710

Change From Baseline for Mini-Mental Status Examination (MMSE) at Baseline, Post-Baseline (up to Month 30)

The MMSE briefly measures orientation to time and place, immediate recall, short-term verbal memory, calculation, language and construct ability. Each area tested had a designated point value, the total score can range from 0 to 30, with a higher score indicating better function. (NCT00967330)
Timeframe: Baseline, Post-Baseline (up to Month 30)

,
Interventionunits on a scale (Least Squares Mean)
Orientation to time and placeImmediate recallRepetitions requiredCalculationsShort-term verbal memoryLanguage and construct abilityTotal Score
Bevacizumab + Irinotecan-0.01771-0.00264-0.05763-0.21530.2012-0.1254-0.2871
Temozolomide-0.2110-0.032190.08530-0.21200.1634-0.2057-0.5999

Change From Baseline in European Organization for Research and Treatment of Cancer Quality of Life Questionnaire Core 30 (EORTC QLQ - C30) at Baseline, Post-Baseline (up to Month 30)

The EORTC QLQ-C30 incorporates: 5 functional scales (physical, role, cognitive, emotional, and social); 9 symptom scales (fatigue, pain, nausea and vomiting, dyspnea, insomnia, appetite loss, constipation, diarrhea and financial difficulties); and a global health and quality-of-life scale. Most questions used 4 point scale (1 'Not at all' to 4 'Very much'; 2 questions used 7-point scale (1 'very poor' to 7 'Excellent'). Scores were averaged and transformed to 0-100 scale; higher score for Global Qol/functional scales=better level of functioning or a higher score for symptom scale=greater degree of symptoms. The change in global health status was determined to be the difference in values at baseline and each specific visit. The term ''baseline'' refers to the time of randomization to the maintenance phase. (NCT00967330)
Timeframe: Baseline, Post-Baseline (up to Month 30)

,
Interventionunits on a scale (Least Squares Mean)
Physical FunctioningRole FunctioningEmotional FunctioningCognitive FunctioningSocial FunctioningGlobal health Status /QoL (ql)FatiqueNausea/VomittingPainDyspnoeaInsomniaAppetite lossConstipationDiarrhoeaFinancial Problems
Bevacizumab + Irinotecan-8.3513-0.76352.2774-2.0188-6.2324-3.11345.52288.955710.68763.7134-2.626613.74238.02306.02304.8435
Temozolomide-6.2511-2.23392.2547-3.8401-4.61980.38552.17794.75971.59260.5046-7.502610.96014.0855-0.14552.1140

Number of Participants With A Best Overall Response (BOR) of Complete Response (CR) and With A BOR of CR or Partial Response (PR)

BOR was defined as the best response observed for a participant during assessment. Number of participants who had BOR as CR and number of participants who had BOR as CR or PR were reported. Complete response was defined as disappearance of all enhancing tumor on consecutive Gd-MRI scans at least 1 month apart, off steroids, and neurologically stable or improved. Partial response was defined as 50% reduction in size of enhancing tumor on consecutive Gd-MRI scans at least 1 month apart, steroids stable or reduced, and neurologically stable or improved. (NCT00967330)
Timeframe: 4 week after radiotherapy (RT) (up to Week 4), >4 Week after RT (up to Week 8) and Month 6

,
Interventionparticipants (Number)
CR at 4 weeks after RT (n=110,46)CR at >4 weeks after RT (n=95,35)CR at Month 6 (n=91,28)CR or PR at 4 Week after RT (n=110,46)CR or PR at >4 Week after RT (n=95,35)CR or PR at Month 6 (n=91,28)
Bevacizumab + Irinotecan1111342185
Temozolomide211633

Percentage of Participants Who Discontinued

Discontinuation was defined as the percentage of participants who permanently discontinued treatment in either treatment arm. Percentage of participant with individual discontinuation reason are reported. CNS: central nervous system; CTCAE: Common Terminology Criteria for Adverse Events . Other reason refers to any other reason than the specified ones. (NCT00967330)
Timeframe: From baseline until death (up to 4.5 years)

,
Interventionpercentage of participants (Number)
Persisting non-hematological toxicity CTCAE Grade3CNS hemorrhagic event (CTCAE Grade >1)Gastro-intestinal perforation (CTCAE Grade 1-4)OtherParticipant's wishProgressive diseaseProteinuria (nephrotic syndrome) (CTCAE Grade 4)RegularRepeated CTCAE Grade 4 hematological toxicityVenous thrombosis/embolismWound dehiscence requiring medical interventionWound dehiscence requiring surgical intervention
Bevacizumab + Irinotecan00.90.99.5674.10.91.700.90.94.3
Temozolomide1.9005.65.657.4027.80.9000

Percentage of Participants With Response on FLAIR Imaging

"FLAIR lesions were determined as stable, progressive or decreased. FLAIR lesions was determined as progressive only if they were not be attributed to causes apart from tumor infiltration (sequelae of radiation therapy, demyelination, ischemia, infection, seizures, or other treatment effects). Percentage of participants are based on ITT population.~Dis.=Discontinuation." (NCT00967330)
Timeframe: At screening, Baseline, Month 6 and Therapy Discontinuation (Up to 4.5 years)

,
Interventionpercentage of participants (Number)
Screening: Initial Flair Lesion (n=116,54)Screening:Stable Flair Lesion (n=116,54)Baseline:Decreased FLAIR Lesions (n=105,46)Baseline:Initial FLAIR Lesions (n=105,46)Baseline:Progressive FLAIR Lesions (n=105,46)Baseline: Stable FLAIR Lesions (n=105,46)Month 6:Progressive FLAIR Lesions (n=91,28)Month 6: Stable FLAIR Lesions (n=91,28)Therapy Dis.:Decreased FLAIR Lesions (n=55,31)Therapy Dis.:Progressiv FLAIR Lesions (n=55,31)Therapy Dis.:Stable FLAIR Lesions (n=55,31)
Bevacizumab + Irinotecan72.417.216.418.114.741.416.462.10.929.317.2
Temozolomide72.216.720.418.511.135.222.229.60.027.829.6

Phase I: Number of Patients With Dose-limiting Toxicity (DLT)

DLT is defined as any of the following events occurring during the first 8 weeks of treatment with RAD001 and temozolomide and attributable to the study drugs: any grade 3 or 4 thrombocytopenia, grade 4 anemia, or grade 4 neutropenia lasting more than 7 days; any non-hematologic grade 3 or greater adverse event (AE), excluding alopecia, despite maximal medical therapy; any grade 4 radiation-induced skin changes; failure to recover from adverse events to be eligible for re-treatment with RAD001 and temozolomide within 14 days of the last dose of either drug; or any episode of non-infectious pneumonitis grade 2, 3, or 4 of any duration. Adverse events are graded using CTCAE v4.0. Grade refers to the severity of the AE. The CTCAE v4.0 assigns Grades 1 through 5 with unique clinical descriptions of severity for each AE based on this general guideline: Grade 1 Mild AE, Grade 2 Moderate AE, Grade 3 Severe AE, Grade 4 Life-threatening or disabling AE, Grade 5 Death related to AE (NCT01062399)
Timeframe: From start of treatment to eight weeks.

InterventionParticipants (Count of Participants)
Ph I: RT + TMZ + RAD001 2.5 mg/Day2
Ph I: RT + TMZ + RAD001 5 mg/Day2
Ph I: RT + TMZ + RAD001 10 mg/Day2

Phase II: Overall Survival (OS)

Overall survival time is defined as time from/randomization to the date of death from any cause and is estimated by the Kaplan-Meier method. Patients last known to be alive are censored at the date of last contact. (NCT01062399)
Timeframe: Analysis occured after 134 events (progression or death) were reported. Patients were followed from randomization to death or study termination whichever occurs first, up to 36.7 months.

Interventionmonths (Median)
Ph II: RT + TMZ21.2
Ph II: RT + TMZ + RAD00116.5

Phase II: Progression-free Survival (PFS)

Using the Response Assessment in Neuro- Oncology (RANO) criteria, the progression is defined by any of the following: > 25% increase in sum of the products of perpendicular diameters of enhancing lesions compared to the smallest tumor measurement obtained either at baseline (if no decrease) or best response, on stable or increasing doses of corticosteroids; Significant increase in T2/FLAIR non-enhancing lesion on stable or increasing doses of corticosteroids compared to baseline scan or best response following initiation of therapy, not due to co-morbid events; Any new lesion; Clear clinical deterioration not attributable to other causes apart from the tumor or changes in corticosteroid dose; Failure to return for evaluation due to death or deteriorating condition; Clear progression of non-measurable disease. PFS time is defined as time from registration to date of progression, death, or last known follow-up (censored). PFS rates are estimated using the Kaplan-Meier method. (NCT01062399)
Timeframe: Analysis occured after 134 events (progression or death) were reported. Patients were followed from randomization to death or study termination whichever occurs first, up to 36.7 months.

Interventionmonths (Median)
Ph II: RT + TMZ10.2
Ph II: RT + TMZ + RAD0018.2

Phase I: Distribution of Worst Adverse Event Grade

"AE reporting in Phase I was split up by treatment timing: concurrent treatment (RT, TMZ, RAD001); post-RT treatment (TMZ, RAD001) along with all AE's reported in follow-up.~The worst/highest grade of any adverse event reported in each time period was determined for each patient. The percentage of patients in each grade level is reported. Adverse events are graded using CTCAE v4.0. Grade refers to the severity of the AE. The CTCAE v4.0 assigns Grades 1 through 5 with unique clinical descriptions of severity for each AE based on this general guideline: Grade 1 Mild AE, Grade 2 Moderate AE, Grade 3 Severe AE, Grade 4 Life-threatening or disabling AE, Grade 5 Death related to AE." (NCT01062399)
Timeframe: Analysis occured after 134 events (progression or death) were reported. Patients were followed from randomization to death or study termination whichever occurs first, up to 36.7 months.

,,
Interventionpercentage of participants (Number)
Concurrent treatment: Grade 1Concurrent treatment: Grade 2Concurrent treatment: Grade 3Concurrent treatment: Grade 4Concurrent treatment: Grade 5Post-RT treatment: Grade 1Post-RT treatment: Grade 2Post-RT treatment: Grade 3Post-RT treatment: Grade 4Post-RT treatment: Grade 5
Ph I: RT + TMZ + RAD001 10 mg/Day12.50.087.50.00.00.0100.00.00.00.0
Ph I: RT + TMZ + RAD001 2.5 mg/Day0.00.050.050.00.00.00.071.414.314.3
Ph I: RT + TMZ + RAD001 5 mg/Day11.133.344.411.10.00.042.928.60.00.0

Phase II: Distribution of Worst Adverse Event Grade

The worst/highest grade of any adverse event reported was determined for each patient. The percentage of patients in each grade level is reported. Adverse events are graded using CTCAE v4.0. Grade refers to the severity of the AE. The CTCAE v4.0 assigns Grades 1 through 5 with unique clinical descriptions of severity for each AE based on this general guideline: Grade 1 Mild AE, Grade 2 Moderate AE, Grade 3 Severe AE, Grade 4 Life-threatening or disabling AE, Grade 5 Death related to AE. (NCT01062399)
Timeframe: Analysis occured after 134 events (progression or death) were reported. Patients were followed from randomization to death or study termination whichever occurs first, up to 36.7 months.

,
Interventionpercentage of patients (Number)
Grade 1Grade 2Grade 3Grade 4Grade 5
Ph II: RT + TMZ00332
Ph II: RT + TMZ + RAD00103501

Overall Survival Rate at 3 Years

Survival time is defined as time from registration to date of death from any cause and is estimated by the Kaplan-Meier method. Patients last known to be alive are censored at the date of last contact. This analysis was planned to occur when all patients had been potentially followed for at least 3 years. (NCT00114140)
Timeframe: Registration to 3 years

Interventionpercentage of participants (Number)
Temozolomide + Radiation Therapy (RT)73.1

Progression-free Survival

"Progressive Disease (PD) is defined as 25% or > increase in the cross-sectional area of enhancing or non-enhancing tumor on consecutive MRI scans, or any new area(s) of tumor. Under exceptional circumstances, disease progression may be declared in the absence of an increase in tumor size based on clinical deterioration including the need for increasing doses of steroid and/or a worsening Karnofsky Performance Status(KPS) / Neurologic Function Score(NFS). Progression-free survival time is defined as time from registration to date of progressive disease or death from any cause and is estimated by the Kaplan-Meier method. Patients last known to be alive are censored at the date of last contact. Median survival time is reported." (NCT00114140)
Timeframe: From registration to last follow-up, up to 7.1 years. Analysis occurs after all patients have been on study for at least 3 years.

Interventionyears (Median)
Temozolomide + Radiation Therapy (RT)4.5

Neurocognitive Function

"Hopkins Verbal Learning Test (HVLT) is a test measuring learning memory retrieval, and memory consolidation processes.; Controlled Oral Word Association Test (COWAT) is a test of phonemic verbal fluency. The patient produces as many words as possible in 1 min. (each) for a specific letter (C, F, L or P, R, W).; Trail Making Test (TMT) is a measure of visuospatial scanning, attention, sequencing, and speed in Part A (TMT A) and executive function in Part B (TMT B). Patients must connect the dots either in a numbered sequence or alternating letters and numbers. Difference between pre-treatment baseline and follow-up assessment scores determined by the reliable change (RC) index, using a 90% confidence interval to designate statistically significant change." (NCT00114140)
Timeframe: Baseline, 6 months, and 12 months.

,
Interventionparticipants (Number)
HVLT Recall Status: DeteriorationHVLT Recall Status: No changeHVLT Recall Status: ImprovementCOWA Status: DeteriorationCOWA Status: No changeCOWA Status: ImprovementTMT A Status: DeteriorationTMT A Status: No changeTMT A Status: ImprovementTMT B Status: DeteriorationTMT B Status: No changeTMT B Status: Improvement
Temozolomide + Radiation Therapy (RT) at 12 Months82215328127241472215
Temozolomide + Radiation Therapy (RT) at 6 Months1126131426152411112711

Quality of Life as Measured by the Functional Assessment of Cancer Therapy Scale With Brain Module (FACT-BR)

Functional Assessment of Cancer Therapy Scale with brain module (FACT-BR): a 50-question self-report questionnaire contains the following domains (scales): Physical well-being (7 questions totalling 0-28), social/family well-being (7 questions totalling 0-28), emotional well-being (6 questions totalling 0-24), functional well-being (7 questions totalling 0-28) and brain cancer subscale which contains concerns relevant to patients with brain tumors (19 questions totalling 0-76). Each question has a value 0-4. For some questions a higher indicates better outcome and others are the opposite. The former are summed as is, the latter are reversed in value before adding, such that each domain ranges from 0 to 4 multiplied by the number of questions in the domain, with 0 indicating worst and the highest possible value indicating best outcome. The FACT-Br total (0-184) is obtained by adding all domains together if the overall question response rate is greater than 80%. (NCT00114140)
Timeframe: Baseline, 6 months, and 12 months.

,,
Interventionunits on a scale (Median)
Physical Well-BeingSocial/Family Well-BeingEmotional Well-BeingFunctional Well-BeingBrain Cancer SubscaleFACT-Br Total
Temozolomide + Radiation Therapy (RT) at 12 Months2324.323.019.559.0140.0
Temozolomide + Radiation Therapy (RT) at 6 Months2224.020.018.052.0129.9
Temozolomide + Radiation Therapy (RT) at Baseline2324.518.517.054.0135.3

Survival and Progression-free Survival by O(6)-Methylguanine-DNA Methyltransferase (MGMT) Methylation Status

"Survival time is defined as time from registration to date of death from any cause. Progressive Disease (PD) is defined as 25% or > increase in the cross-sectional area of enhancing or non-enhancing tumor on consecutive MRI scans, or any new area(s) of tumor. Under exceptional circumstances, disease progression may be declared in the absence of an increase in tumor size based on clinical deterioration including the need for increasing doses of steroid and/or a worsening Karnofsky Performance Status(KPS) / Neurologic Function Score(NFS). Survival and progression-free survival are estimated by the Kaplan-Meier method. Patients last known to be alive are censored at the date of last contact." (NCT00114140)
Timeframe: Registration to 3 years

,
Interventionyears (Median)
Overall SurvivalProgression-free Survival
Temozolomide + Radiation Therapy (RT) - MethylatedNANA
Temozolomide + Radiation Therapy (RT) - Unmethylated3.02.0

Median Duration of Overall Survival

Duration of overall survival for patients that are alive (NCT03034135)
Timeframe: 14 months

Interventionmonths (Median)
DSF-Cu7.1

Median Progression Free Survival

Duration of progression free survival according to RANO criteria (NCT03034135)
Timeframe: 12 months

Interventionmonths (Median)
DSF-Cu1.7

Number of Participants With Serious Adverse Events

Number of Participants with Grade 3 and 4 serious adverse events (NCT03034135)
Timeframe: 14 months

InterventionParticipants (Count of Participants)
DSF-Cu2

Progression Free Survival

Percentage of patients that are free from progressive disease per RANO criteria (NCT03034135)
Timeframe: 6 months

Interventionpercentage of participants (Number)
DSF-Cu14

Objective Response Rate

ORR will be defined as the percentage of patients with complete response (CR) or partial response (PR) according to the RANO criteria. (NCT03034135)
Timeframe: 6 months

InterventionParticipants (Count of Participants)
Complete responsePartial Response
DSF-Cu00

Overall Survival

Percentage of patients that are alive (NCT03034135)
Timeframe: 6 months and 12 months

Interventionpercentage of participants (Number)
6 months12 months
DSF-Cu6135

Overall Survival

Median overall survival (NCT03072134)
Timeframe: Two years

InterventionMonths (Median)
Total Cohort18.4

Percentage of Dose-limiting Toxicities

Using a 3+3 dose escalation design, three to six patients were to be enrolled per dose in each of the 3 cohorts. If no patients in the cohort experienced a dose-limiting toxicity (DLT), then the next cohort enrolled a minimum of 3 patients. If one of three patients experienced a DLT, then 3 more patients were evaluated at that dose level. If none of these three additional patients experienced a DLT, then dose escalation occurs, unless this is the highest dose, in which case dose escalation is stopped and the highest dose is declared the MTD. If 1 or more of these additional 3 patients had a DLT, then three additional patients may be entered, after discussion with the sponsor, at the next lowest does level if only three patients were treated previously at that dose. If two or more patients experienced a DLT Dose escalation will be stopped; 3 more patients could be added with sponsor approval at the next lower dose level. (NCT03072134)
Timeframe: Two years

InterventionPercentage of dose-limiting toxicities (Number)
Arm B/Cohort 10
Arm B/Cohort 20
ArmB/Cohort 317

Progression-free Survival

Median progression-free survival (NCT03072134)
Timeframe: two years

InterventionMonths (Median)
Total Cohort9.1

Assessment of Tumor Response.

Per Response Assessment in Neuro-Oncology Criteria (RANO, 2017) for target lesions as assessed by MRI: Complete Response (CR): The enhancing tumor is no longer seen by neuroimaging; Partial Response (PR): Decrease of ≥ 50% in the product of two diameters with the patient on a stable or decreasing dose of steroids; Minor Response (MR): Decrease in diameter products of < 50% with the patient on a stable or decreasing dose of steroids; Stable Disease (SD): The scan shows no change. Patients should be receiving stable or decreasing doses of steroids; Progression (P): Increase of > 25% in tumor area (two diameters) provided that the patient has not had his/her dose of steroids decreased since the last evaluation period. A concomitant decrease in steroid dose will rule out a progression designation during the first two months after completion of radiation; Pseudoprogression (PP): Radiological changes without concomitant neurological changes. (NCT03072134)
Timeframe: Two years

InterventionPercentage of participants (Number)
Percentage of participants with tumor response: PartialPercentage of participants with tumor response: PseudoprogressionPercentage of participants with tumor response: Stable disease
Total Cohort8884

Determination of Impactful Baseline Instruments on Overall Survival

Overall survival time is defined as time from registration/randomization to the date of death from any cause or last known follow-up (censored). Overall survival rates are estimated by the Kaplan-Meier method. The European Organization for Research and Treatment of Cancer Quality of Life Questionnaire [EORTC QLQ]-C30 subscales are calculated as the mean of component items, then standardized such that subscale scores range from 0 to 100. A high score for a functional scale represents a healthy level of functioning. Controlled Oral Word Association (COWA) score is the sum of correct responses with a range of 0 to infinity. A higher score indicates better functioning. Hopkins Verbal Learning Test - Revised (HVLT-R) score ranges from 0 to 36 for total recall is 0 to 36, 0 to 12 for delayed recall, and -12 to 12 for recognition. A higher score indicates better functioning. (NCT00304031)
Timeframe: From randomization to last follow-up. Maximum follow-up at time of analysis was 4.4 years.

Interventionmonths (Median)
Both Arms Combined17.5

Mean Change From Baseline in EORTC QLQ-C30 Global Health Status Score at Mid-cyle for Cycle 1

"Global Health Status is calculated from two questions on the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire [EORTC QLQ]-C30. The question responses range from 1 very poor to 7 excellent such that a higher response indicates better quality of life (QOL). The mean of these responses is linearly transformed to a range of 0 (worst) to 100 (best). Change is calculated as time point - baseline such that a positive change value indicates worse symptoms compared to baseline." (NCT00304031)
Timeframe: Baseline and mid-cycle 1 (approximately 12 weeks)

Interventionscore on a scale (Mean)
Conventional Adjuvant TMZ-4.58
Dose-dense Adjuvant TMZ-2.63

Mean Change From Baseline in EORTC QLQ-C30 Global Health Status Score at Mid-cyle for Cycle 4

"Global Health Status is calculated from two questions on the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire [EORTC QLQ]-C30. The question responses range from 1 very poor to 7 excellent such that a higher response indicates better quality of life (QOL). The mean of these responses is linearly transformed to a range of 0 (worst) to 100 (best). Change is calculated as time point - baseline such that a positive change value indicates worse symptoms compared to baseline." (NCT00304031)
Timeframe: Baseline and mid-cycle 4 (approximately 24 weeks)

Interventionscore on a scale (Mean)
Conventional Adjuvant TMZ-2.78
Dose-dense Adjuvant TMZ-0.72

Mean Change From Baseline in MD Anderson Symptom Inventory Brain Tumor (MDASI-BT) Symptom Severity Score at Mid-cyle for Cycle 1

The MDASI-BT is a 28-item patient-reported outcome measure assessing symptom severity and resulting interference with daily living in brain cancer patients. All items range from 0 (not present) to 10 (as bad as you can imagine). The symptom severity score is the average of the symptom severity items, given a specified minimum numbers were completed. A score worse than baseline by at least one is considered deterioration. Change is calculated as time point - baseline such that a positive change value indicates worse symptoms compared to baseline. (NCT00304031)
Timeframe: Baseline and mid-cycle 1 (approximately 12 weeks)

Interventionscore on a scale (Mean)
Conventional Adjuvant TMZ0.48
Dose-dense Adjuvant TMZ0.39

Mean Change From Baseline in MD Anderson Symptom Inventory Brain Tumor (MDASI-BT) Symptom Severity Score at Mid-cyle for Cycle 4

The MDASI-BT is a 28-item patient-reported outcome measure assessing symptom severity and resulting interference with daily living in brain cancer patients. All items range from 0 (not present) to 10 (as bad as you can imagine). The symptom severity score is the average of the symptom severity items, given a specified minimum numbers were completed. A score worse than baseline by at least one is considered deterioration. Change is calculated as time point - baseline such that a positive change value indicates worse symptoms compared to baseline. (NCT00304031)
Timeframe: Baseline and mid-cycle 4 (approximately 24 weeks)

Interventionscore on a scale (Mean)
Conventional Adjuvant TMZ-0.23
Dose-dense Adjuvant TMZ0.19

Mean EORTC QLQ-C30 Global Health Status Score at Cycle 10 for Participants Without Progression After 6 Months of Adjuvant Therapy

"Global Health Status is calculated from two questions on the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire [EORTC QLQ]-C30. The question responses range from 1 very poor to 7 excellent such that a higher response indicates better quality of life (QOL). The mean of these responses is linearly transformed to a range of 0 (worst) to 100 (best)." (NCT00304031)
Timeframe: Baseline and cycle 10 (approximately 46 weeks)

Interventionscore on a scale (Mean)
Conventional Adjuvant TMZ73.3
Dose-dense Adjuvant TMZ69.7

Mean MD Anderson Symptom Inventory Brain Tumor (MDASI-BT) Symptom Severity Score at Cycle 10 for Participants Without Progression After 6 Months of Adjuvant Therapy

The MDASI-BT is a 28-item patient-reported outcome measure assessing symptom severity and resulting interference with daily living in brain cancer patients. All items range from 0 (not present) to 10 (as bad as you can imagine). The symptom severity score is the average of the symptom severity items, given a specified minimum numbers were completed. (NCT00304031)
Timeframe: Baseline and cycle 10 (approximately 46 weeks)

Interventionscore on a scale (Mean)
Conventional Adjuvant TMZ1.17
Dose-dense Adjuvant TMZ1.18

Mean Neurocognitive Function (NCF) Composite Score at Cycle 10 for Participants Without Progression After 6 Months of Adjuvant Therapy

The NCF Composite score is the arithmetic mean of the Hopkins Verbal Learning Test - Revised (HVLT-R) (Free Recall, Delayed Recall, Delayed Recognition), Trail Making Test Part A (TMTA), Trail Making Test Part B (TMTB), and Controlled Oral Word Association (COWA) test scores, all of which are standardized, adjusting for age, education, and gender as necessary, such that mean is 0 and standard deviation is 1. A participant must have at least 5 of the 6 scores. A higher composite score indicates better neurocognitive function. (NCT00304031)
Timeframe: Baseline and cycle 10 (approximately 46 weeks)

Interventionscore on a scale (Mean)
Conventional Adjuvant TMZ-0.95
Dose-dense Adjuvant TMZ-1.19

Median Overall Survival Time

Overall survival time is defined as time from registration/randomization to the date of death from any cause. Overall survival rates are estimated by the Kaplan-Meier method. Patients last known to be alive are censored at the date of last contact. Analysis occurred after 647 deaths were reported. (NCT00304031)
Timeframe: From randomization to last follow-up. Maximum follow-up at time of analysis was 4.4 years.

Interventionmonths (Median)
Conventional Adjuvant TMZ16.6
Dose-dense Adjuvant TMZ14.9

Median Progression-free Survival (PFS) Time

Progression is defined as greater than 25% increase in tumor area (two diameters) provided that the patient has not had his/her dose of steroids decreased since the last evaluation period. Progression-free survival time is defined as time from registration to the date of first progression, death, or last known follow-up (censored). Progression-free survival rates are estimated using the Kaplan-Meier method. A concomitant decrease in steroid dose will rule out a progression designation during the first 2 months after completion of radiation therapy. Analysis occurred after 647 deaths were reported. (NCT00304031)
Timeframe: From randomization to last follow-up. Maximum follow-up at time of analysis was 4.4 years.

Interventionmonths (Median)
Conventional Adjuvant TMZ5.5
Dose-dense Adjuvant TMZ6.7

Number of Participants With Deterioration From Baseline in MD Anderson Symptom Inventory Brain Tumor (MDASI-BT) Interference Score at Cycle 4

The MDASI-BT is a 28-item patient-reported outcome measure assessing symptom severity and resulting interference with daily living in brain cancer patients. All items range from 0 (did not interfere) to 10 (interfered completely). The symptom interference score is the average of the symptom interference items, given a specified minimum numbers were completed. A score worse than baseline by at least one is considered deterioration. (NCT00304031)
Timeframe: baseline and cycle 4 (approximately 22 weeks)

InterventionParticipants (Count of Participants)
Conventional Adjuvant TMZ7
Dose-dense Adjuvant TMZ13

Number of Participants With Deterioration From Baseline in MD Anderson Symptom Inventory Brain Tumor (MDASI-BT) Symptom Severity Score at Cycle 4

The MDASI-BT is a 28-item patient-reported outcome measure assessing symptom severity and resulting interference with daily living in brain cancer patients. All items range from 0 (not present) to 10 (as bad as you can imagine). The symptom severity score is the average of the symptom severity items, given a specified minimum numbers were completed. A score worse than baseline by at least one is considered deterioration. (NCT00304031)
Timeframe: baseline and cycle 4 (approximately 22 weeks)

InterventionParticipants (Count of Participants)
Conventional Adjuvant TMZ5
Dose-dense Adjuvant TMZ11

Overall Survival Status by Progression Status at 6 Months

Overall survival time is defined as time from registration to the date of death from any cause or last known follow-up (censored). Overall survival rates are estimated by the Kaplan-Meier method. Progression is defined as greater than 25% increase in tumor area (two diameters) provided that the patient has not had his/her dose of steroids decreased since the last evaluation period. (NCT00304031)
Timeframe: From randomization to last follow-up. Maximum follow-up at time of analysis was 4.4 years.

Interventionmonths (Median)
No Progression at 6 Months20.7
Progression at 6 Months10.1

Change From Baseline in Mean EORTC QLQ-C30 Global Health Status

"Global Health Status is calculated from two questions on the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire [EORTC QLQ]-C30. The question responses range from 1 very poor to 7 excellent such that a higher response indicates better quality of life (QOL). The mean of these responses is linearly transformed to a range of 0 (worst) to 100 (best). Change from baseline was calculated as time point value - baseline value with a positive change value indicating improved QOL from baseline." (NCT00304031)
Timeframe: Baseline, 10,12, 22, 24, and 46 weeks

,
Interventionscore on a scale (Mean)
Week 10 (Cycle 1)Week 12 (Cycle 1.5)Week 22 (Cycle 4)Week 24 (Cycle 4.5)Week 46 (Cycle 10)
Conventional Adjuvant TMZ0.0-4.63.9-2.85.4
Dose-dense Adjuvant TMZ-2.9-2.7-4.4-0.7-1.9

Mean MD Anderson Symptom Inventory Brain Tumor (MDASI-BT) Symptom Severity Score Over Time

The MDASI-BT is a 28-item patient-reported outcome measure assessing symptom severity and resulting interference with daily living in brain cancer patients. All items range from 0 (not present) to 10 (as bad as you can imagine). The symptom severity score is the average of the symptom severity items, given a specified minimum numbers were completed. (NCT00304031)
Timeframe: Baseline, 10, 12, 22, 24, and 46 weeks

,
Interventionscore on a scale (Mean)
BaselineWeek 10 (Cycle 1)Week 12 (Cycle 1.5)Week 22 (Cycle 4)Week 24 (Cycle 4.5)Week 46 (Cycle 10)
Conventional Adjuvant TMZ1.31.41.61.01.01.2
Dose-dense Adjuvant TMZ1.11.41.51.21.11.1

Mean Neurocognitive Function (NCF) Composite Score Over Time

The NCF Composite score is the arithmetic mean of the HVLT-R (Free Recall, Delayed Recall, Delayed Recognition), TMTA, TMTB, and COWA scores, all of which are standardized, adjusting for age, education, and gender as necessary, such that mean is 0 and standard deviation is 1. A participant must have at least 5 of the 6 scores. A higher composite score indicates better neurocognitive function. (NCT00304031)
Timeframe: Baseline, 10, 22, and 46 weeks

,
Interventionscore on a scale (Mean)
BaselineWeek 10 (Cycle 1)Week 22 (Cycle 4)Week 46 (Cycle 10)
Conventional Adjuvant TMZ-1.2-1.3-1.1-1.0
Dose-dense Adjuvant TMZ-1.5-1.45-1.3-1.2

Median Overall Survival Time by MGMT Status

Overall survival time is defined as time from randomization to the date of death from any cause. Overall survival rates are estimated by the Kaplan-Meier method. Patients last known to be alive are censored at the date of last contact. Tumor tissue submitted at baseline was analyzed to determine MGMT (O[6]-methylguanine-DNA methyltransferase) promoter methylation status (methylated / unmethylated). Analysis occurred after 647 deaths were reported. (NCT00304031)
Timeframe: From randomization to last follow-up. Maximum follow-up at time of analysis was 4.4 years.

,
Interventionmonths (Median)
Unmethylated MGMTMethylated MGMT
Conventional Adjuvant TMZ14.621.4
Dose-dense Adjuvant TMZ13.320.2

Median Progression-free Survival Time by MGMT Status

Progression is defined as greater than 25% increase in tumor area (two diameters) provided that the patient has not had his/her dose of steroids decreased since the last evaluation period. Progression-free survival time is defined as time from registration to the date of first progression, death, or last known follow-up (censored). Progression-free survival rates are estimated using the Kaplan-Meier method. A concomitant decrease in steroid dose will rule out a progression designation during the first 2 months after completion of radiation therapy. Tumor tissue submitted at baseline was analyzed to determine MGMT (O[6]-methylguanine-DNA methyltransferase) promoter methylation status (methylated / unmethylated). Analysis occurred after 647 deaths were reported. (NCT00304031)
Timeframe: From randomization to last follow-up. Maximum follow-up at time of analysis was 4.4 years.

,
Interventionmonths (Median)
Unmethylated MGMTMethylated MGMT
Conventional Adjuvant TMZ5.16.5
Dose-dense Adjuvant TMZ6.010.1

Summary of the Median Progression-free Survival (mPFS) in the Study Group Compared With Historical Control From Medical Literature

mPFS was based on model parameters estimated by maximum likelihood with a Newton-Raphson algorithm. The Radiation Therapy Oncology Group (RTOG) 0525 study was the main historical control used for statistical analysis. Additionally, RTOG-0825 was also used to support this outcome measure. (NCT01790503)
Timeframe: Assessed from date of first dose administered to date of first documented progression or date of death from any cause, whichever came first, assessed up to 4 years 4 months.

Interventionmonths (Median)
RP2D7.7
RP2D-0525 (Cycle 1, Day 1)7.6
RP2D-08257.0
RP2D-0525 (Rest Period, Day 15)6.1

Summary of the Overall Survival in the Study Group Compared With Historical Control From Medical Literature

Overall Survival was calculated using a parametric model. The Radiation Therapy Oncology Group (RTOG) 0525 study was the main historical control used for statistical analysis. Additionally, RTOG-0825 was also used to support this outcome measure (NCT01790503)
Timeframe: Assessed from date of first dose administered to the date of death from any cause, assessed up to 4 years 4 months.

Interventionmonths (Median)
RP2D18.8
RP2D-0525 (Cycle 1, Day 1)20.2
RP2D-082517.0
RP2D-0525 (Rest Period, Day 15)16.9

Number of Patients With Clinically Significant Abnormal Chemistry and Hematology Values Reported as Adverse Events by Preferred Term in Phase 1b of the Modified Intent-To-Treat Population

(NCT01790503)
Timeframe: Baseline up to 30 days after last dose, up to 4 years 4 months

,,,,,,,,
InterventionParticipants (Count of Participants)
ThrombocytopeniaNeutropeniaAnaemiaLymphopeniaAST increasedPlatelet count decreasedNeutrophil count decreasedLeukopeniaFebrile neutropeniaALT increasedBone marrow failureHaemolysisWhite blood cell decreasedLymphocyte count decreased
Phase 1b Dose Escalation - 600 mg00000000000100
Phase 1b Dose Escalation - 600 mg/1000 mg00001001010000
Phase 1b Dose Escalation - 600 mg/600 mg10110010000000
Phase 1b Dose Escalation - 600 mg/800 mg11010001000000
Phase 1b Dose Escalation - 800 mg (5 Days)11000100000001
Phase 1b Dose Escalation - 800 mg/1000 mg11112100110000
Phase 1b Dose Escalation - 800 mg/600 mg00000000000000
Phase 1b Dose Escalation - 800 mg/800 mg10000000000000
Phase 1b Dose Escation - 800 mg (No Adjuvant Therapy)11100120101010

Number of Patients With Clinically Significant Abnormal Chemistry and Hematology Values Reported as Adverse Events by Preferred Term in Phase 2, the Combined RP2D Groups in Phase 1b, and in the Study Overall Modified Intent-To-Treat Population

(NCT01790503)
Timeframe: Baseline up to 30 days after last dose, up to 4 years 4 months

,,,
InterventionParticipants (Count of Participants)
NeutropeniaThrombocytopeniaAnaemiaALT increasedAST increasedPlatelet count decreasedLymphopeniaWhite blood cell count decreasedNeutrophil count decreasedLeukopeniaFebrile neutropeniaLymphocyte count decreasedBlood alkaline phosphatase increasedBlood creatinine increasedDRESSLiver function test abnormalBone marrow failureHaemolysisBlood bilirubin increasedBlood iron decreased
Combined 800 mg, 5 Days/Week96788745222333110111
Phase 2 - 800 mg11154111011131110010
Phase 2 - 800 mg/800 mg63522424210102000001
Phase 2 Total74676535221233110011

Overview of Most Frequent System Organ Classes Reported in Phase 1b of the Modified Intent-To-Treat Population

(NCT01790503)
Timeframe: Baseline up to 30 days after last dose, up to 4 years 4 months

,,,,,,,,
InterventionParticipants (Count of Participants)
General Disorders and Administrative SiteNervous System DisordersSkin and Subcutaneous Tissue DisordersGastrointestinal DisordersMetabolism and Nutrition DisordersPsychiatric DisordersInfections and InfestationsInvestigationsRespiratory, Thoracic, and Mediastinal DisordersMusculoskeletal and Connective Tissue DisordersBlood and Lymphatic Tissue DisordersVascular DisordersRenal and Urinary DisordersEye DisordersInjury, Poisoning, and Procedural ComplicationsEar and LabyrinthEndocrine DisordersCardiac DisordersHepatobiliary DisordersReproductive System and Breast DisordersImmune System DisordersNeoplasms Benign, Malignant, and Unspecified
Phase 1b Dose Escalation - 600 mg1221121101111011000000
Phase 1b Dose Escalation - 600 mg/1000 mg1111111110100000000000
Phase 1b Dose Escalation - 600 mg/600 mg2333321110101110000000
Phase 1b Dose Escalation - 600 mg/800 mg0111110000100000000000
Phase 1b Dose Escalation - 800 mg5443211233121100010000
Phase 1b Dose Escalation - 800 mg/1000 mg5555435432133221100100
Phase 1b Dose Escalation - 800 mg/600 mg1100010101000000000000
Phase 1b Dose Escalation - 800 mg/800 mg1010100000100000000000
Phase 1b Dose Escation - 800 mg3212213321121101101000

Overview of Most Frequent System Organ Classes Reported in Phase 2 of the Modified Intent-To-Treat Population

(NCT01790503)
Timeframe: Baseline up to 30 days after last dose, up to 4 years 4 months

,,,
InterventionParticipants (Count of Participants)
General Disorders and Administration SiteSkin and Subcutaneous Tissue DisordersNervous System DisordersGastrointestinal DisordersMetabolism and Nutrition DisordersPsychiatric DisordersInvestigationsMusculoskeletal and Connective Tissue DisordersBlood and Lymphatic System DisordersInjury, Poisoning, and Procedural ComplicationsEye DisordersVascular DisordersRespiratory, Thoracic, and Mediastinal DisordersRenal and Urinary DisordersCardiac DisordersEndocrine DisordersEar and Labyrinth DisordersReproductive System and Breast DisordersNeoplasms Benign, Malignant, and UnspecifiedHepatobiliary DisordersImmune System Disorders
Combined 800 mg, 5 Days/Week47454341302727251818161816138753211
Phase 2 - 800 mg1312121286972664322110010
Phase 2 - 800 mg/800 mg2424222116171213141079775532201
Phase 2 Total3736343324232120161613131097642211

Summary of the Median Progression-free Survival (mPFS) by Subgroups in the Modified Intent-To-Treat Population on the Recommended Phase 2 Dose

"Progression was determined by Response Assessment in Neuro-Oncology (RANO) criteria and progression-free survival (PFS) was analyzed based on the non-parametric Kaplan-Meier method. mPFS was analyzed by age group, extent of surgery, baseline Karnofsky Performance Status (KPS), and O6-methylguanine-DNA methyltransferase status (MGMT).~The scale range for the baseline Karnofsky Performance Status is from 0-100, with 0 indicating that the participant is dead and 100 indicating that the participant is Normal no complaints, no evidence of disease. The higher the number, the better the outcome." (NCT01790503)
Timeframe: Assessed from date of first dose administered to date of first documented progression or date of death from any cause, whichever came first, assessed up to 4 years 4 months.

Interventionmonths (Median)
Age: 18-64 yearsAge: 65+ yearsExtent of surgery: complete resectionExtent of surgery: partial resectionBaseline KPS: 70-89Baseline KPS: 90-100MGMT status: methylatedMGMT status: unmethylated
Combined 800 mg, 5 Days/Week61069411104

Summary of the Median Progression-free Survival (mPFS) in the Combined 800 mg, 5 Days/Week Dose Group

Progression was determined by Response Assessment in Neuro-Oncology (RANO) criteria and progression-free survival (PFS) was analyzed based on the non-parametric Kaplan-Meier method. (NCT01790503)
Timeframe: Assessed from date of first dose administered to date of first documented progression or date of death from any cause, whichever came first, assessed up to 4 years 4 months.

Interventionmonths (Median)
mITT RP2DPP RP2D
Combined 800 mg, 5 Days/Week6.76.9

Summary of the Overall Survival by Subgroups in the Modified Intent-To-Treat Population on the Recommended Phase 2 Dose

"Overall Survival was calculated using a non-parametric Kaplan-Meier analysis method. Median OS was analyzed by age group, extent of surgery, baseline Karnofsky Performance Status (KPS), and O6-methylguanine-DNA methyltransferase status (MGMT).~The scale range for the baseline Karnofsky Performance Status is from 0-100, with 0 indicating that the participant is dead and 100 indicating that the participant is Normal no complaints, no evidence of disease. The higher the number, the better the outcome." (NCT01790503)
Timeframe: Assessed from date of first dose administered to the date of death from any cause, assessed up to 4 years 4 months.

Interventionmonths (Median)
Age group: 18-64 yearsAge group: 65+ yearsExtent of surgery: complete resectionExtent of surgery: partial resectionBasline KPS: 70-89Baseline KPS: 90-100MGMT status: methylatedMGMT: unmethylated
Combined 800 mg, 5 Days/Week14.31114138241512

Summary of the Overall Survival in The Study Population

Overall Survival (OS) was defined as the number of days from the first day of treatment (C1D1) to the date of death and analyzed using a non-parametric Kaplan Meier method. (NCT01790503)
Timeframe: Assessed from date of first dose administered to date of death from any cause, assessed up to 4 years 4 months

Interventionmonths (Median)
mITT RP2DPP RP2D
Combined 800 mg, 5 Days/Week13.112.4

Summary of Best Overall Response by Subgroups in the Modified Intent-To-Treat Population on the Recommended Phase 2 Dose

Best Overall Response (based on the RANO response) was defined as the highest overall response recorded from the start of study treatment until the end of treatment. Per the Response Assessment in Neuro-Oncology (RANO) criteria for measurable lesions and assessed by Cranial MRI scan, summarized as: Complete Response (CR), Disappearance of all enhancing disease (measurable and non-measurable); Partial Response (PR), >=50% decrease of all measurable enhancing lesions; Stable disease, does not qualify for complete response, partial response, or progression, and progression, >25% increase in enhancing lesions despite stable or increasing steroid use or any new lesions. (NCT01790503)
Timeframe: Assessed from Baseline and every 8 weeks, up to 4 years 4 months

InterventionParticipants (Count of Participants)
Age group: 18-64 years72008643Age group: 65+ years72008643Complete resection72008643Partial resection72008643Baseline KPS: 70-8972008643Baseline KPS: 90-10072008643MGMT status: methylated72008643MGMT status: unmethylated72008643
Complete response (CR)Partial response (PR)CR+PRStable diseaseProgressive diseaseUnable to accessUnknown
Combined 800 mg, 5 Days/Week18
Combined 800 mg, 5 Days/Week10
Combined 800 mg, 5 Days/Week5
Combined 800 mg, 5 Days/Week1
Combined 800 mg, 5 Days/Week3
Combined 800 mg, 5 Days/Week4
Combined 800 mg, 5 Days/Week13
Combined 800 mg, 5 Days/Week6
Combined 800 mg, 5 Days/Week0
Combined 800 mg, 5 Days/Week7
Combined 800 mg, 5 Days/Week8
Combined 800 mg, 5 Days/Week2
Combined 800 mg, 5 Days/Week17
Combined 800 mg, 5 Days/Week11
Combined 800 mg, 5 Days/Week12
Combined 800 mg, 5 Days/Week9

Apparent Diffusion Coefficient Before, During, and After Chemoradiotherapy

"Apparent diffusion coefficient (ADC) is a measure of the magnitude of diffusion (of water molecules) within tissue. ADC was assessed using post-contrast T1-weighted images. Multiple images were used to assess each participant at every time-point and the median value for each participant was calculated by time-point. The data presented represent the average of those median values at each time-point.~CRT: Chemoradiotherapy Cx: The cycle number TMZ: temozolomide" (NCT00756106)
Timeframe: Baseline, weekly during treatment, monthly following treatment for up to six months

Interventionmm2/s (Mean)
Baseline 1Baseline 2Week 1 CRTWeek 2 CRTWeek 3 CRTWeek 4 CRTWeek 5 CRTWeek 6 CRTPre-C1 TMZPre-C2 TMZPre-C3 TMZPre-C4 TMZPre-C5 TMZPre-C6 TMZPost-TMZ
Temozolomide and Radiation Therapy0.001100.001130.001060.001100.001180.001220.001250.001250.001320.001270.001080.001330.001480.001790.00140

Permeability-surface Area Product Before, During, and After Chemoradiotherapy

"Permeability-surface Area Product (Ktrans). Ktrans reflects the efflux rate of contrast from blood plasma into the tissue extravascular extracellular space (EES). Ktrans was assessed using post-contrast T1-weighted images. Multiple images were used to assess each participant at every time-point and the median value for each participant was calculated by time-point. The data presented represent the average of those median values at each time-point.~CRT: Chemoradiotherapy Cx: The cycle number TMZ: temozolomide" (NCT00756106)
Timeframe: Baseline, weekly during treatment, monthly following treatment for up to six months

Interventionmin ^-1 (Mean)
Baseline 1Baseline 2Week 1 CRTWeek 2 CRTWeek 3 CRTWeek 4 CRTWeek 5 CRTWeek 6 CRTPre-C1 TMZPre-C2 TMZPre-C3 TMZPre-C4 TMZPre-C5 TMZPre-C6 TMZPost-TMZ
Temozolomide and Radiation Therapy0.0530.0390.0550.0480.0550.0530.0580.0590.0630.0420.0500.0580.0560.0600.032

Relative Cerebral Blood Flow as Measured by Perfusion-weighted MRI Before, During, and After Chemoradiotherapy

"Relative cerebral blood flow (rCBF) is the blood flow rate (the volume of blood passing through the specified are over a specified period of time) in the region of interest (ROI) divided by the blood flow rate in the symmetrical region on the other side of the normal brain (control region). CBF was assessed using spin-echo post-contrast T1-weighted images. CBF was assessed using spin-echo post-contrast T1-weighted images. Multiple images were used to assess each participant at every time-point and the median value for each participant was calculated by time-point. The data presented represent the average of those median values at each time-point. The baseline value was measured twice (representing baseline 1 and 2) to make sure that the value was reproducible and to account for any variation attributable to measurement variation.~CRT: Chemoradiotherapy Cx: The cycle number TMZ: temozolomide" (NCT00756106)
Timeframe: Baseline, weekly during treatment, monthly following treatment for up to six months

Interventionratio (Mean)
Baseline 1Baseline 2Week 1 CRTWeek 2 CRTWeek 3 CRTWeek 4 CRTWeek 5 CRTWeek 6 CRTPre-C1 TMZPre-C2 TMZPre-C3 TMZPre-C4 TMZPre-C5 TMZPre-C6 TMZPost-TMZ
Temozolomide and Radiation Therapy0.830.860.920.940.800.790.830.730.630.590.600.600.520.470.37

Relative Cerebral Blood Volume as Measured by Perfusion-weighted MRI Before, During, and After Chemoradiotherapy

"Relative cerebral blood volume (rCBV) is the blood volume in the region of interest (ROI) divided by the blood volume in the symmetrical region on the other side of the normal brain (control region). CBV was assessed using spin-echo post-contrast T1-weighted images. Multiple images were used to assess each participant at every time-point and the median value for each participant was calculated by time-point. The data presented represent the average of those median values at each time-point. The baseline value was measured twice (representing baseline 1 and 2) to make sure that the value was reproducible and to account for any variation attributable to measurement variation.~CRT: Chemoradiotherapy Cx: The cycle number TMZ: temozolomide" (NCT00756106)
Timeframe: Baseline, weekly during treatment, monthly following treatment for up to six months

Interventionratio (Mean)
Baseline 1Baseline 2Week 1 CRTWeek 2 CRTWeek 3 CRTWeek 4 CRTWeek 5 CRTWeek 6 CRTPre-C1 TMZPre-C2 TMZPre-C3 TMZPre-C4 TMZPre-C5 TMZPre-C6 TMZPost-TMZ
Temozolomide and Radiation Therapy0.880.900.951.00.880.830.860.760.680.610.590.650.610.640.32

Maximum Tolerated Dose(MTD)of Temozolomide(TMZ)

This study is designed as a phase I dose escalation trial using the Standard Method of dose escalation of three patients per dose level to determine the MTD of TMZ (up to 75 mg/m 2 /day) when TMZ is used with HIMRT for patients with glioblastoma multiforme(GBM) or Anaplastic Astrocytoma(AA)of the brain. The 3 dose levels will be evaluated using the standard method to determine if either represents an MTD based on DLT. If DLT is not observed at all doses level, the greater of the three levels will be recommended for phase II evaluations of treatment effect. (NCT00841555)
Timeframe: up to 12-16 months

Interventionmg/m^2 (Number)
Hypofractionation Radiotherapy+Temozolomide75

Survival Time

All patients will be followed to death. Active follow-up with disease evaluation with scans will be terminated if the patient's physician deems it in the patient's interest not to continue or upon patient request. (NCT00841555)
Timeframe: up to 2 years

Interventionmonths (Median)
Hypofractionation Radiotherapy+Temozolomide12.7

Time Spent in a Karnofsky Performance Status of 60-100%

Time spent in a KPS ≥70 was calculated from the date of diagnosis of Karonofsky Performance Status decline (KPS<70) or censored at the last date the patient was known with KPS ≥70. The KPS higher scores indicates normal activity status. (NCT00841555)
Timeframe: up to 12-16 months

Interventionmonths (Median)
Hypofractionation Radiotherapy+Temozolomide8.1

Co-Primary: Overall Survival (OS)

Overall Survival was defined as the time from randomization to death due to any cause. (NCT00943826)
Timeframe: Randomization until OS Event (Until data cutoff= 28 February 2013 [up to 42.2 months])

InterventionMonths (Median)
Bevacizumab + RT + Temozolomide16.8
Placebo + RT + Temozolomide16.7

Co-Primary: Progression-free Survival (PFS) as Assessed by Investigator

PFS is defined as time from randomization to disease progression (PD) or death. PD was assessed using adapted Macdonald response criteria (modified World Health Organization [WHO] criteria) based on 3 components: radiological tumor assessments using Magnetic Resonance Imaging [MRI] scans,neurological assessment and changes in corticosteroid use. PD is assessed as greater than or equal to(>=) 25% increase in sum of products of the longest diameters of all index lesions (enhancing,measurable) compared with the smallest recorded sum (nadir); or unequivocal PD of existing non-index lesions (non-enhancing and enhancing,non-measurable); or unequivocal appearance of new lesions); or neurological worsening (if corticosteroid dose is stable or increased) compared to neurological evaluation at previous disease assessment with no need for a confirmatory scan. Participants without a PFS event were censored at last disease assessment. (NCT00943826)
Timeframe: Randomization until PFS Event [Until data cutoff= 31 March 2012 (up to 31.4 months)

InterventionMonths (Median)
Bevacizumab + RT + Temozolomide10.6
Placebo + RT + Temozolomide6.2

Kaplan-Meier (KM) Estimate of One Year Overall Survival

KM estimate of one year overall survival (probability to survive for at least 1 year) was reported. Corresponding 95% confidence interval (CI) was calculated using Greenwood's formula. (NCT00943826)
Timeframe: Randomization until Overall Survival Event (Until data cutoff= 28 February 2013 [up to 42.2 months])

Interventionprobability of being alive (Number)
Bevacizumab + RT + Temozolomide0.72
Placebo + RT + Temozolomide0.66

Kaplan-Meier (KM) Estimate of Two Year Overall Survival

KM estimate of two year overall survival was reported (probability to survive for at least 2 years). Corresponding 95% CI was calculated using Greenwood's formula. (NCT00943826)
Timeframe: Randomization until Overall Survival Event (Until data cutoff= 28 February 2013 [up to 42.2 months])

Interventionprobability of being alive (Number)
Bevacizumab + RT + Temozolomide0.34
Placebo + RT + Temozolomide0.30

PFS as Assessed by an Independent Review Facility

An Independent Review Facility reviewed the MRI scans used by investigator to evaluate radiological tumor response. PFS is defined as time from randomization to PD or death. PD was assessed using adapted Macdonald response (modified WHO) criteria based on 3 components: radiological tumor assessments using MRI scans, neurological assessment and changes in corticosteroid use. PD is assessed as >=25% increase in sum of products of the longest diameters of all index lesions (enhancing, measurable) compared with the smallest recorded sum (nadir); or unequivocal PD of existing non-index lesions (non-enhancing and enhancing, non-measurable); or unequivocal appearance of new lesions); or neurological worsening (if corticosteroid dose is stable or increased) compared to neurological evaluation at previous disease assessment with no need for a confirmatory scan. Participants without a PFS event were censored at last disease assessment. (NCT00943826)
Timeframe: Randomization until PFS Event (Until data cutoff= 31 March 2012 [up to 29.5 months])

InterventionMonths (Median)
Bevacizumab + RT +Temozolomide8.4
Placebo + RT + Temozolomide4.3

Number of Participants With Non-Serious Adverse Events, Serious Adverse Events and Death

An adverse event (AE) was considered any unfavorable and unintended sign, symptom, or disease associated with the use of the study drug, whether or not considered related to the study drug. Preexisting conditions that worsened during the study were reported as AE.A serious adverse event (SAE) is any experience that suggests a significant hazard,contraindication, side effect or precaution that: results in death, is life-threatening, required in-patient hospitalization or prolongation of existing hospitalization, results in persistent or significant disability/incapacity, is a congenital anomaly/birth defect or is medically significant. Non-serious adverse events (Non-SAEs) included all AEs except SAEs (non-SAEs = all AEs - SAEs). Nine participants randomized to the Placebo+RT+Temozolomide arm incorrectly received at least 1 dose of bevacizumab and were added to the Bevacizumab+RT+Temozolomide arm for Safety. (NCT00943826)
Timeframe: Randomization until study completion (Until data cutoff= 09 Sep 2015 [up to 64 months])

,
InterventionParticipants (Number)
Non-SAEsSAEsDeath
Bevacizumab + RT + Temozolomide437179335
Placebo + RT + Temozolomide412115337

PFS in Participants With Stable/Improved Health Related Quality of Life (HRQoL) Based on European Organization for Research & Treatment of Cancer (EORTC) Quality of Life Questionnaire (QLQ) Core 30 (C30)(EORTC QLQ-C30) & EORTC QLQ Brain Neoplasm 20 (BN20)

EORTC QLQ-C30: 30 items; 5 functional scales; 9 symptom scales; & global health status. Most questions used 4-point scale (1:Not at all, 4:Very much), 2 questions used 7-point scale (1:very poor, 7:Excellent). EORTC QLQ-BN20: 20 items rated on a 4 point scale (1:not at all, 4:very much). EORTC QLQ-C30 and BN20 scores were transformed to a 0-100 scale, higher score=better functioning/global health (C30) or more severe symptoms (BN20). Stable HRQoL: change from baseline (BL) within 10 points. Improved HRQoL: an increase from BL >/=10 points for functioning/global health status, & decrease of >/=10 points for symptoms. PFS is reported for participants with Stable/Improved global health; physical, social functioning (C30); motor dysfunction & communication deficit (BN20). PFS: randomization to PD or death. PD: >=25% increase in sum of products of longest diameters of index lesions; or progression of existing non-index lesions; or appearance of new lesions; or neurological worsening. (NCT00943826)
Timeframe: Randomization until PFS Event [Until data cutoff= 31 March 2012 (up to 31.4 months)

,
InterventionMonths (Median)
Global health status (n=354, 309)Physical functioning (n=353, 318)Social functioning (n=352, 327)Motor dysfunction (n=361, 314)Communication deficit (n=365, 329)
Bevacizumab + RT + Temozolomide87878
Placebo + RT + Temozolomide45444

Incidence of Grade 3 and Higher Treatment-related Toxicity as Assessed by the National Cancer Institute Common Terminology Criteria for Adverse Events (AEs) Version 3.0

AEs are graded by using CTCAE 3.0. The difference between the two randomized arms in the percentage of patients with grade 3 or higher toxicities reported as possibly/probably/definitely related to protocol treatment will be tested using a chi square test. (NCT00884741)
Timeframe: Up to 30 days

Interventionparticipants (Number)
Randomized Arm 1: TMZ+RT + Placebo87
Randomized Arm 2: TMZ+RT + Bevacizumab97

Overall Survival (OS)

Survival time was defined as time from randomization to date of death from any cause and was estimated by the Kaplan-Meier method. Patients last known to be alive were censored at the date of last contact. This analysis was planned to occur when 390 deaths had been reported. (NCT00884741)
Timeframe: From randomization to date of death or last follow-up. Analysis occurs after all 390 deaths have been reported.

Interventionmonths (Median)
Randomized Arm 1: TMZ+RT + Placebo16.1
Randomized Arm 2: TMZ+RT + Bevacizumab15.7

Progression-free Survival (PFS)

Progression-free survival was defined as time from randomization to date of progression, death, or last follow-up, and was estimated by the Kaplan-Meier method. Patients last known to be alive were censored at the date of last contact. This analysis was planned to occur when 390 deaths had been reported. (NCT00884741)
Timeframe: From randomization to date of progression, death, or last follow-up for progression-free survival. Analysis occurs after all 390 deaths have been reported.

Interventionmonths (Median)
Randomized Arm 1: TMZ+RT + Placebo7.3
Randomized Arm 2: TMZ+RT + Bevacizumab10.7

Overall Survival (OS)

Overall survival was defined from the date of diagnosis to date of death from any cause (NCT00525525)
Timeframe: Approximately 6-24 months

Interventionmonths (Median)
Efficacy Group19.8

Progression-free Survival

Progression-free survival was defined from the date of diagnosis to the date that progressive disease was first observed on imaging, or the date at which nonreversible neurologic progression or permanently increased corticosteroid requirement, death from any cause, or early discontinuation of treatment. Imaging guidelines were used to evaluate progression: (i) 25% increase in the sum of products of all measurable lesions over the smallest sum observed (over baseline if no decrease) using the same techniques as baseline; (ii) clear worsening of any assessable disease; (iii) appearance of any new lesion/site; and (iv) clear clinical worsening or failure to return for evaluation as a result of death or deteriorating condition (unless clearly unrelated to this cancer). (NCT00525525)
Timeframe: Approximately 6 months to 1 year

Interventionmonths (Median)
Efficacy Group13.5

Unexpected Toxicities During First 2 Cycles of Study Drug

Unexpected severe study-related adverse events (NCT00525525)
Timeframe: Within 8 weeks of initiating study therapy

InterventionEvents (Number)
Safety Lead-in Group0

6 Month Progression-free Survival

Efficacy of dose-intense temozolomide treatment schedule, as measured by 6 months progression-free survival (NCT00619112)
Timeframe: First day of treatment until progression or until 6 months mark

Interventionpercentage of patients (Number)
Glioblastoma10
Grade III Glioma50

Overall Survival

(NCT00619112)
Timeframe: up to 2 years after treatment

Interventionweeks (Median)
Glioblastoma21.6
Grade III Glioma100.6

Patients Progressing 6 Months After Temozolomide is Voluntarily Discontinued

(NCT00619112)
Timeframe: From beginning of voluntarily temozolomide discontinued up to 6 months

InterventionParticipants (Count of Participants)
Glioblastoma4
Grade III Glioma4

Patients Progressing After Two First-line Adjuvant Courses of Temozolomide

(NCT00619112)
Timeframe: After two first-line adjuvant courses of temozolomide

InterventionParticipants (Count of Participants)
Glioblastoma3
Grade III Glioma0

Patients Progressing Within 6 Months After 6th Adjuvant Course of Temozolomide

(NCT00619112)
Timeframe: Within 6 months after 6th adjuvant course of temozolomide

InterventionParticipants (Count of Participants)
Glioblastoma4
Grade III Glioma1

Patients With Tumors With Functional Alterations of the Mismatch Repair (MMR) System

PCR analysis of tumor tissue for microsatellite instability (MSI). Tissue was obtained during surgeries prior this study. (NCT00619112)
Timeframe: prior to start of study

InterventionParticipants (Count of Participants)
Glioblastoma0
Grade III Glioma0

Progression-free Survival (PFS) Based on Tumor MGMT (O(6)-Methylguanine-DNA Methyltransferase) Promoter Methylation Status.

Progression-free survival data (obtained for Primary Outcome Measure) was correlated with tumor MGMT (O(6)-methylguanine-DNA methyltransferase) promoter methylation status, obtained from patients as part of the study. (NCT00619112)
Timeframe: First day of treatment until progression or until 6 months mark

Interventionweeks (Median)
Glioblastoma With Methylated MGMT8.14
Glioblastoma With Unmethylated MGMT7.57
Grade III Glioma With Methylated MGMT38.1
Grade III Glioma With Unmethylated MGMT48.6

(Phase I) Number of Participants Who Experienced Dose Limiting Toxicity (DLT)

Dose limiting toxicity defined as: Any DLT must be a toxicity considered at least possibly related to HCQ. DLTs will include any possibly, probably, or definitely HCQ-related Grade 3 or 4 toxicity. Known or reasonably suspected TMZ hematological toxicities will not be considered dose limiting unless the treating physician considers the toxicity to be exacerbated by HCQ. Nonhematological toxicities: Any Grades 3-4 severity (except nausea and vomiting without sufficient antiemetic prophylaxis) (NCT00486603)
Timeframe: 10 weeks

InterventionParticipants (Count of Participants)
Phase 1: RT+TMZ+HCQ - 200mg0
Phase 1: RT+TMZ+HCQ - 400mg0
Phase 1: RT+TMZ+HCQ - 600mg0
Phase 1: RT+TMZ+HCQ - 800mg3

(Phase II) Number of Participants With Grade 3 and 4 Toxicity

Number of participants experiencing Grade 3 and 4 toxicity, as defined by CTCAE v3.0, with a possible, probable or definite relationship to HCQ, TMZ or both (NCT00486603)
Timeframe: up to 2 years

InterventionParticipants (Count of Participants)
Phase 2: RT + TMZ + HCQ22

(Phase II) Overall Survival

Number of months alive after end of study participation (NCT00486603)
Timeframe: 2 years

Interventionmonths (Median)
Phase 2: RT + TMZ + HCQ15.6

Pharmacokinetics (PK) of Hydroxychloroquine as Measured by Lag Time (Tlag)

The population model PK parameters do not specifically represent steady-state values, as they were determined from multiple repeated single doses taken from multiple repeated doses taken by the individual patient during their period on the study. To obtain steady state PK parameters, individual estimates were simulated from the population model. (NCT00486603)
Timeframe: up to 276 days

Interventionhour (Mean)
Phase 2: RT + TMZ + HCQ1.06

PK of Hydroxychloroquine as Measured by Distribution Volume of Peripheral Compartment (V2/F)

The population model PK parameters do not specifically represent steady-state values, as they were determined from multiple repeated single doses taken from multiple repeated doses taken by the individual patient during their period on the study. To obtain steady state PK parameters, individual estimates were simulated from the population model. (NCT00486603)
Timeframe: up to 276 days

InterventionLiters (Mean)
Phase 2: RT + TMZ + HCQ963

PK of Hydroxychloroquine as Measured by First-order Absorption Rate Constant (Ka)

The population model PK parameters do not specifically represent steady-state values, as they were determined from multiple repeated single doses taken from multiple repeated doses taken by the individual patient during their period on the study. To obtain steady state PK parameters, individual estimates were simulated from the population model. (NCT00486603)
Timeframe: up to 276 days

Interventionhours (Mean)
Phase 2: RT + TMZ + HCQ0.51

PK of Hydroxychloroquine as Measured by Oral Clearance (Liters/Hour) From Central Compartment (CL/F)

The population model PK parameters do not specifically represent steady-state values, as they were determined from multiple repeated single doses taken from multiple repeated doses taken by the individual patient during their period on the study. To obtain steady state PK parameters, individual estimates were simulated from the population model. (NCT00486603)
Timeframe: up to 276 days

InterventionL/hr (Mean)
Phase 2: RT + TMZ + HCQ11.85

PK of Hydroxychloroquine as Measured by Volume of Distribution of Central Compartment (V/F)

The population model PK parameters do not specifically represent steady-state values, as they were determined from multiple repeated single doses taken from multiple repeated doses taken by the individual patient during their period on the study. To obtain steady state PK parameters, individual estimates were simulated from the population model. (NCT00486603)
Timeframe: up to 276 days

InterventionLiters (Mean)
Phase 2: RT + TMZ + HCQ483.96

(Phase I) Maximum Tolerated Dose (MTD) of Hydroxychloroquine (HCQ)

Number of participants who tolerated doses of HCQ without dose limiting toxicity. The highest dose at which participants did not experience dose limiting toxicity was determined as the MTD. (NCT00486603)
Timeframe: 10 weeks

InterventionParticipants (Count of Participants)
200mg400mg600mg800mg
Phase 1 - Dose Finding3730

Pharmocodynamics as Determined by Number of Participants With Autophagy Inhibition in Relation to Maximal Concentration (Cmax) of HCQ

Autophagy inhibition is represented by an increase in autophagic vacuoles (AV) in participants with at least 2 peripheral blood mononuclear cell samples that were amenable to EM. (NCT00486603)
Timeframe: up to 9 weeks

,
InterventionParticipants (Count of Participants)
AV IncreaseNo AV Increase
HCQ Cmax <= 1785 ng/mL1012
HCQ Cmax>1785 ng/mL126

Number of Participants Who Had Brain Metastases

Brain Metastases were defined as radiological evidence of brain metastases on magnetic resonance imaging (MRI). (NCT00632203)
Timeframe: Up to 12 months (as measured from day 1 of cycle 1 of standard first-line systemic chemotherapy)

Interventionparticipants (Number)
Temozolomide Treatment4
Observation3

Overall Survival

The overall survival was analyzed using the Kaplan-Meier method. (NCT00632203)
Timeframe: from Cycle 1 Day 1 of Standard First Line Systemic Therapy to the last time of follow-up

Interventionmonths (Median)
Temozolomide Treatment27.14
Observation22.54

Time to Progression

"The time to progression (per response evaluation criteria in solid tumors [RECIST]) was analyzed using the Kaplan-Meier method.~Definitions of response per RECIST:~Complete Response (CR): Disappearance of all target lesions.~Partial Response (PR): A decrease of at least 30% in the sum of the longest~diameter of target lesions.~Progressive Disease (PD): An increase of at least 20% in the sum of the longest~diameter of target lesions.~Stable Disease (SD): Neither sufficient shrinkage to qualify for partial response nor sufficient increase to qualify for progressive disease." (NCT00632203)
Timeframe: from Cycle 1 Day 1 of Standard First Line Systemic Therapy to progression or up to 6 cycles (168 days) of study treatment

Interventionmonths (Median)
Temozolomide Treatment11.70
Observation10.68

Time to Radiological Central Nervous System (CNS) Progression

"Defined as CNS progression as measured by MRI.~Time to CNS progression was analyzed using the Kaplan-Meier method." (NCT00632203)
Timeframe: from Cycle 1 Day 1 of Standard First Line Systemic Therapy to radiological progression or the last known CNS progression-free date

Interventionmonths (Median)
Temozolomide TreatmentNA
ObservationNA

Tolerability of Maintenance Temozolomide

Tolerability was defined as number of participants with any adverse event leading to study discontinuation and/or study drug discontinuation. (NCT00632203)
Timeframe: from Cycle 1 Day 1 of Standard First Line Systemic Therapy to the last time of follow-up (up to 6 cycles (168 days) of study treatment)

Interventionparticipants (Number)
Temozolomide Treatment5
ObservationNA

Duration of Response

From the onset of temozolomide to the date at which unequivocal disease progression, assessed up to 65 months. (NCT00669669)
Timeframe: Up to 65 months

Interventionmonths (Median)
Treatment (Chemotherapy, Autologous Stem Cell Transplant)4.5

Gene Transfer Efficiency

Assessed by gene marking in peripheral blood prior to chemoselection. Gene marking is assessed in whole blood by quantitative PCR and reported as a vector copy number (VCN) or the average copies of integrated transgene per cell. The units here will be reported as copies/cell. (NCT00669669)
Timeframe: Up to 59 months

Interventioncopies/cell (Mean)
Treatment (Chemotherapy, Autologous Stem Cell Transplant)0.78

Gene Transfer Efficiency After Chemotherapy

Assessed by gene marking in peripheral blood after chemoselection. Gene marking is assessed in whole blood by quantitative PCR and reported as a vector copy number (VCN) or the average copies of integrated transgene per cell. The units here will be reported as copies/cell. (NCT00669669)
Timeframe: Up to 59 months

Interventioncopies/cell (Mean)
Treatment (Chemotherapy, Autologous Stem Cell Transplant)0.50

Number of Participants Dose-limiting Toxicity (DLT)

Defined as any grade 4 nonhematopoietic toxicity that is likely related to the investigational procedures (Part I) (NCT00669669)
Timeframe: Up to 6 weeks after infusion

InterventionParticipants (Count of Participants)
Treatment (Chemotherapy, Autologous Stem Cell Transplant)1

Number of Participants That Survived

From the first day of treatment until death, assessed up to 74 months. (NCT00669669)
Timeframe: Up to 74 months

InterventionParticipants (Count of Participants)
Treatment (Chemotherapy, Autologous Stem Cell Transplant)0

Number of Participants With Chemoprotection

assessed by the ability to increase the Temozolomide dose beyond 472 mg/m^2 (NCT00669669)
Timeframe: Up to 66 months

InterventionParticipants (Count of Participants)
Treatment (Chemotherapy, Autologous Stem Cell Transplant)2

Number of Participants With Chemoselection

assessed by the increase in peripheral blood Vector Copy Number (VCN), the average copies of integrated transgene per cell, after chemotherapy (NCT00669669)
Timeframe: Up to 59 months

InterventionParticipants (Count of Participants)
Treatment (Chemotherapy, Autologous Stem Cell Transplant)4

Number of Participants With Retrovirus or Leukemia

Replication competent retrovirus or diagnosis of leukemia (NCT00669669)
Timeframe: Up to 2 years after infusion

InterventionParticipants (Count of Participants)
Treatment (Chemotherapy, Autologous Stem Cell Transplant)0

Response Rate

Number of patients with reduction in tumor burden of a predefined amount (NCT00669669)
Timeframe: Up to 66 months

InterventionParticipants (Count of Participants)
Treatment (Chemotherapy, Autologous Stem Cell Transplant)1

Time to Progression

From the first day of treatment (transplant) until unequivocal progression is documented, assessed up to 66 months. (NCT00669669)
Timeframe: Up to 66 months.

Interventionmonths (Median)
Treatment (Chemotherapy, Autologous Stem Cell Transplant)5.5

Area Under the Plasma Concentration Curve From Time 0 to 6 Hours (AUC [0-6]) After Dose

The AUC (0-6) for cilengitide was calculated by non-compartmental analysis using the computer program WinNonlin, Version 6.2.1. (NCT00689221)
Timeframe: Day 1 of Week -1

Interventionhour*ng/mL (Mean)
Cilengitide + Temozolomide + Radiotherapy295171.2

EuroQol 5-Dimensions (EQ-5D) Questionnaire Index

The EuroQuol-5D (EQ-5D) questionnaire is a measure of health status that provides a simple descriptive profile and a single index value. The optional part of the questionnaire was not applied. The EQ-5D defines health in terms of mobility, self-care, usual activities, pain/discomfort and anxiety/depression. The 5 items are combined to generate health profiles. These profiles were converted to a continuous single index score using a one to one matching. The lowest possible score is -0.594 (death) and the highest is 1.00 (full health). (NCT00689221)
Timeframe: Up to 50 months

Interventionunits on a scale (Mean)
Cilengitide + Temozolomide + Radiotherapy0.598
Temozolomide + Radiotherapy0.623

Maximum Observed Plasma Concentration (Cmax)

The Cmax for cilengitide was calculated by non-compartmental analysis using the computer program WinNonlin, Version 6.2.1. (NCT00689221)
Timeframe: Day 1 of Week -1

Interventionnanogram per milliliter (ng/mL) (Mean)
Cilengitide + Temozolomide + Radiotherapy167363.2

Overall Survival (OS) Time

The OS time is defined as the time (in months) from randomization to death or last day known to be alive. Participants without event are censored at the last date known to be alive or at the clinical cut-off date, whatever is earlier. (NCT00689221)
Timeframe: Time from randomization to death or last day known to be alive, reported between day of first participant randomized, that is, Sep 2008 until cut-off date, (19 Nov 2012)

InterventionMonths (Median)
Cilengitide + Temozolomide + Radiotherapy26.3
Temozolomide + Radiotherapy26.3

Time to Maximum Plasma Concentration (Tmax)

The Tmax for cilengitide was calculated by non-compartmental analysis using the computer program WinNonlin, Version 6.2.1. (NCT00689221)
Timeframe: Day 1 of Week -1

Interventionhours (Mean)
Cilengitide + Temozolomide + Radiotherapy1.029

European Organization for the Research and Treatment of Cancer Quality of Life Questionnaire Brain Module (EORTC QLQ-BN20) Sub-scale Scores

The QLQ-BN20 is a questionnaire specifically designed as the QLQ-C30 supplement for the evaluation of quality of life in brain tumor participants. It includes 4 multi-item sub-scales: future uncertainty, visual disorder, motor dysfunction, communication deficits, and 7 single-item scales: headaches, seizures, drowsiness, itchy skin, hair loss, weakness of legs, and bladder control. All items are rated on a 4-point Likert-type scale ('1=not at all', '2=a little', '3=quite a bit' and '4=very much'), and are linearly transformed to a 0-100 scale, with higher scores indicating more severe symptoms. (NCT00689221)
Timeframe: Up to 50 months

,
Interventionunits on a scale (Mean)
Future Uncertainty (n=68, 86)Visual Disorder (n=68, 85)Motor Dysfunction (n=68, 86)Communication Deficit (n=68, 86)Headaches (n=68, 86)Seizures (n=68, 87)Drowsiness (n=66, 87)Itchy Skin (n=68, 86)Hair Loss (n=66, 86)Weakness of Legs (n=67, 85)Bladder Control (n=67, 85)
Cilengitide + Temozolomide + Radiotherapy44.4912.9927.4526.1425.989.3138.389.8013.1324.3819.40
Temozolomide + Radiotherapy39.3117.7823.3919.9621.718.0535.2513.5715.1220.3910.20

European Organization for the Research and Treatment of Cancer Quality of Life Questionnaire Core 30 (EORTC QLQ-C30) Sub-scale Scores

The EORTC QLQ-C30 is a questionnaire including following sub-scales: global health status, functional scales (physical functioning, role functioning, emotional functioning, cognitive functioning, and social activity), symptom scales (fatigue, nausea and vomiting, and pain) and single items (dyspnoea, insomnia, appetite loss, constipation, diarrhoea and financial difficulties). Scores are averaged for each scale and transformed to 0-100 scale; higher score indicates better quality of life on global health status and functional scales and worse quality of life on symptom scales and financial difficulty scale. (NCT00689221)
Timeframe: Up to 50 months

,
Interventionunits on a scale (Mean)
Global Health Status (n=71, 92)Physical Functioning (n=71, 92)Role Functioning (n=71, 92)Emotional Functioning (n=71, 93)Cognitive Functioning (n=70, 93)Social Activity (n=71, 93)Fatigue (n=71, 92)Nausea and Vomiting (n=71, 93)Pain (n=71, 93)Dyspnoea (n=71, 92)Insomnia (n=71, 91)Appetite Loss (n=71, 92)Constipation (n=71, 93)Diarrhoea (n=70, 92)Financial Difficulties (n=71, 93)
Cilengitide + Temozolomide + Radiotherapy54.3465.7056.3467.4964.0556.3444.3710.3322.3015.9620.6621.1318.786.6727.23
Temozolomide + Radiotherapy55.4367.4656.3467.0065.4162.7239.737.7124.3713.0420.5115.9413.984.3522.94

Number of Participants With Adverse Events (AEs), Serious AEs, Treatment-Related AEs, Treatment-Related Serious AEs, AEs Leading to Death, Treatment Related AEs Leading to Death, AEs of Grade 3 or 4 and Treatment Related AEs of Grade 3 or 4

An AE is defined as any new untoward medical occurrences/worsening of pre-existing medical condition without regard to possibility of causal relationship. Treatment-emergent AEs are the events between first dose of study drug and up to 28 days after last dose of study treatment. A Serious AE is an AE that resulted in any of the following outcomes: death; life threatening; persistent/significant disability/incapacity; initial or prolonged inpatient hospitalization; congenital anomaly/birth defect. Treatment-related AEs are the AEs which are suspected to be reasonably related to the study treatment (cilengitide, or radiotherapy, or temozolomide) as per investigator assessment. The severity of AEs was assessed according to the National Cancer Institute-Common Toxicity Criteria (NCI-CTCAE) (version 3.0): Grade 1=mild, Grade 2=moderate, Grade 3=severe, Grade 4=life threatening or disabling. Note: Death (Grade 5) was regarded as an outcome. (NCT00689221)
Timeframe: Time from first dose up to 28 days after last dose of study treatment, reported between day of first participant randomized, that is, Sep 2008 until cut-off date (19 Nov 2012)

,
InterventionParticipants (Number)
AEsSerious AEsTreatment-related AEsTreatment-Related Serious AEsAEs leading to deathTreatment-related AEs leading to deathAEs with NCI-CTC toxicity Grade 3 or 4Treatment-related AEs of Grade 3 or 4
Cilengitide + Temozolomide + Radiotherapy26113822955113169100
Temozolomide + Radiotherapy2531152224793158101

Number of Participants With AEs Belonging to Standardized Medical Dictionary for Regulatory Activities (MedDRA) Queries (SMQs) Thromboembolic Events and Hemorrhage With NCI-CTC Toxicity Grade 3 or 4

Thromboembolic events (standardized MedDRA query [SMQ]) Grade 3 or 4 AEs encompassed hemiparesis and cerebrovascular accident, pulmonary embolism, and deep vein thrombosis. Thromboembolic events (SMQ) of any grade and of Grade 3 or 4 were generally more frequent in the Cilengitide + Temozolomide/Radiotherapy group than in the Temozolomide/Radiotherapy group but were still in the expected range of this patient population The severity of AEs was assessed according to the National Cancer Institute-Common Toxicity Criteria (NCI-CTCAE) (version 3.0): Grade 1=mild, Grade 2=moderate, Grade 3=severe, Grade 4=life threatening or disabling. Note: Death (Grade 5) was regarded as an outcome. (NCT00689221)
Timeframe: Time from first dose up to 28 days after last dose of study treatment, reported between day of first participant randomized, that is, Sep 2008 until cut-off date (19 Nov 2012)

,
InterventionParticipants (Number)
SMQ:Thromboembolic eventsSMQ: Hemorrhage
Cilengitide + Temozolomide + Radiotherapy354
Temozolomide + Radiotherapy234

Number of Participants With Change From Baseline in Work Status at End of Study

Number of participants with change from baseline in work status (working full time [FT], part-time [PT], unemployed/retired [U/R]) at end of study (EOS) (up to cut-off date, [19 Nov 2012]) was reported. For the category 'part-time', the following sub-categories were defined: part-time due to basic disease (PT1); part-time not due to basic disease (PT2); part-time reason not known (PT3). (NCT00689221)
Timeframe: Baseline, End of study (up to cut-off date, [19 Nov 2012])

,
Interventionparticipants (Number)
Baseline: FT, EOS: FTBaseline: FT, EOS: PT1Baseline: FT, EOS: PT2Baseline: FT, EOS: PT3Baseline: FT, EOS: U/RBaseline: PT1, EOS: FTBaseline: PT1, EOS: PT1Baseline: PT1, EOS: PT2Baseline: PT1, EOS: PT3Baseline: PT1, EOS: U/RBaseline: PT2, EOS: FTBaseline: PT2, EOS: PT1Baseline: PT2, EOS: PT2Baseline: PT2, EOS: PT3Baseline: PT2, EOS: U/RBaseline: PT3, EOS: FTBaseline: PT3, EOS: PT1Baseline: PT3, EOS: PT2Baseline: PT3, EOS: PT3Baseline: PT3, EOS: U/RBaseline: U/R, EOS: FTBaseline: U/R, EOS: PT1Baseline: U/R, EOS: PT2Baseline: U/R, EOS: PT3Baseline: U/R, EOS: U/RBaseline: Missing, EOS: FTBaseline: Missing, EOS: PT1Baseline: Missing, EOS: PT2Baseline: Missing, EOS: PT3Baseline: Missing, EOS: U/RBaseline: Missing, EOS: Missing
Cilengitide + Temozolomide + Radiotherapy3210243300900015000005510199000011
Temozolomide + Radiotherapy61002221001210004000008710191000011

Progression Free Survival (PFS) Time - Investigator and Independent Read

"The PFS time is defined as the duration from randomization to either first observation of progressive disease (PD) or occurrence of death due to any cause. Investigator read is the assessment of all imaging by the treating physician at the local trial site and Independent Read is the assessment of all imaging centrally by an Independent Review Committee (IRC). Investigator's assessed progression according to MacDonald criteria and IRC by Response Assessment in Neuro-Oncology Working Group (RANO) criteria using Gadolinium-enhanced magnetic resonance imaging.~Investigator and IRC read: Progression is defined as greater than 25 percent increase in the sum of the product of the largest perpendicular diameters of enhancing tumor compared to the smallest prior sum, or Worsening of an evaluable lesion(s),or Marked increase in T2/FLAIR non-enhancing lesions (IRC only) or Any new lesion" (NCT00689221)
Timeframe: Time from randomization to disease progression, death or last tumor assessment, reported between day of first participant randomized, that is, Sep 2008 until cut-off date, (19 Nov 2012)

,
InterventionMonths (Median)
PFS Time: Investigator readPFS Time: Independent read
Cilengitide + Temozolomide + Radiotherapy13.510.6
Temozolomide + Radiotherapy10.77.9

Median Overall Survival (OS) Comparison of Celecoxib Arms Versus no Celecoxib Arms

Celecoxib versus not Celecoxib analysis: We compared the median OS outcome of participants in arms III, V, VI and VIII, versus participants in arms I, II, IV and VII. Median OS was estimated using the Kaplan-Meier method from time of randomization to time of progression, death, or last follow-up. Progression defined as 25% increase in the sum of products of all measurable lesions over smallest sum observed (over baseline if no decrease) using the same techniques as baseline, OR clear worsening of any evaluable disease, OR appearance of any new lesion/site, OR failure to return for evaluation due to death or deteriorating condition (unless clearly unrelated to this cancer). (NCT00112502)
Timeframe: Every 3 months from randomization until progression of disease, death or last follow-up.

Interventionmonths (Median)
Celecoxib: Arm III, Arm V, Arm VI and Arm VIII20.2
No Celecoxib: Arm I, Arm II, Arm IV and Arm VII17.1

Median Overall Survival (OS) Comparison of Doublet Versus Triplet Therapy

Doublet (2 agents) versus Triplet (3 agents) therapy analysis: We compared the median OS outcome of participants in arms II, III, IV, versus participants in arms V, VI and VII. Median OS was estimated using the Kaplan-Meier method from time of randomization to time of progression, death, or last follow-up. Progression defined as 25% increase in the sum of products of all measurable lesions over smallest sum observed (over baseline if no decrease) using the same techniques as baseline, OR clear worsening of any evaluable disease, OR appearance of any new lesion/site, OR failure to return for evaluation due to death or deteriorating condition (unless clearly unrelated to this cancer). (NCT00112502)
Timeframe: Every 3 months from randomization until progression of disease, death or last follow-up.

Interventionmonths (Median)
Doublet (2 Agents): Arm II, Arm III and Arm IV17.0
Triplet (3 Agents): Arm V, Arm VI and Arm VII20.1

Median Overall Survival (OS) Comparison of Isotretinoin Arms Versus no Isotretinoin Arms

Isotretinoin versus not Isotretinoin analysis: We compared the median OS outcome of participants in arms IV, V, VII and VIII, versus participants in arms I, II, III and VI. Median OS was estimated using the Kaplan-Meier method from time of randomization to time of progression, death, or last follow-up. Progression defined as 25% increase in the sum of products of all measurable lesions over smallest sum observed (over baseline if no decrease) using the same techniques as baseline, OR clear worsening of any evaluable disease, OR appearance of any new lesion/site, OR failure to return for evaluation due to death or deteriorating condition (unless clearly unrelated to this cancer). (NCT00112502)
Timeframe: Every 3 months from randomization until progression of disease, death or last follow-up.

Interventionmonths (Median)
Isotretinoin: Arm IV, Arm V, Arm VII and ARM VIII17.1
No Isotretinoin: Arm I, Arm II, Arm III and ARM VI19.9

Median Overall Survival (OS) Comparison of Thalidomide Arms Versus no Thalidomide Arms

Thalidomide versus not Thalidomide analysis: We compared the median OS outcome of participants in arms II, VI, VII and VIII, versus participants in arms I, III, IV and V. Median OS was estimated using the Kaplan-Meier method from time of randomization to time of progression, death, or last follow-up. Progression defined as 25% increase in the sum of products of all measurable lesions over smallest sum observed (over baseline if no decrease) using the same techniques as baseline, OR clear worsening of any evaluable disease, OR appearance of any new lesion/site, OR failure to return for evaluation due to death or deteriorating condition (unless clearly unrelated to this cancer). (NCT00112502)
Timeframe: Every 3 months from randomization until progression of disease, death or last follow-up.

Interventionmonths (Median)
Thalidomide: Arm II, Arm VI, Arm VII and Arm VIII18.3
No Thalidomide: Arm I, Arm III, Arm IV and Arm V17.4

Median Progression-Free Survival (PFS) Comparison of Celecoxib Arms Versus no Celecoxib Arms

Celecoxib versus not Celecoxib analysis: We compared the median PFS outcome of participants in arms III, V, VI and VIII, versus participants in arms I, II, IV and VII. Median PFS was estimated using the Kaplan-Meier method from time of randomization to time of progression, death, or last follow-up. Progression defined as 25% increase in the sum of products of all measurable lesions over smallest sum observed (over baseline if no decrease) using the same techniques as baseline, OR clear worsening of any evaluable disease, OR appearance of any new lesion/site, OR failure to return for evaluation due to death or deteriorating condition (unless clearly unrelated to this cancer). (NCT00112502)
Timeframe: Every 2 cycles (1 cycle = 28 days) from randomization until progression of disease, death or last follow-up.

Interventionmonths (Median)
Celecoxib: Arm III, Arm V, Arm VI and Arm VIII8.3
No Celecoxib: Arm I, Arm II, Arm IV and Arm VII7.4

Median Progression-Free Survival (PFS) Comparison of Doublet Versus Triplet Therapy

Doublet (2 agents) versus Triplet (3 agents) therapy analysis: We compared the median PFS outcome of participants in arms II, III, IV, versus participants in arms V, VI and VII. Median PFS was estimated using the Kaplan-Meier method from time of randomization to time of progression, death, or last follow-up. Progression defined as 25% increase in the sum of products of all measurable lesions over smallest sum observed (over baseline if no decrease) using the same techniques as baseline, OR clear worsening of any evaluable disease, OR appearance of any new lesion/site, OR failure to return for evaluation due to death or deteriorating condition (unless clearly unrelated to this cancer). (NCT00112502)
Timeframe: Every 2 cycles (1 cycle = 28 days) from randomization until progression of disease, death or last follow-up.

Interventionmonths (Median)
Doublet (2 Agents): Arm II, Arm III and Arm IV8.3
Triplet (3 Agents): Arm V, Arm VI and Arm VII8.2

Median Progression-Free Survival (PFS) Comparison of Isotretinoin Arms Versus no Isotretinoin Arms

Isotretinoin versus not Isotretinoin analysis: We compared the median PFS outcome of participants in arms IV, V, VII and VIII, versus participants in arms I, II, III and VI. Median PFS was estimated using the Kaplan-Meier method from time of randomization to time of progression, death, or last follow-up. Progression defined as 25% increase in the sum of products of all measurable lesions over smallest sum observed (over baseline if no decrease) using the same techniques as baseline, OR clear worsening of any evaluable disease, OR appearance of any new lesion/site, OR failure to return for evaluation due to death or deteriorating condition (unless clearly unrelated to this cancer). (NCT00112502)
Timeframe: Every 2 cycles (1 cycle = 28 days) from randomization until progression of disease, death or last follow-up.

Interventionmonths (Median)
Isotretinoin: Arm IV, Arm V, Arm VII and Arm VIII6.6
No Isotretinoin: Arm I, Arm II, Arm III and Arm VI9.1

Median Progression-Free Survival (PFS) Comparison of Thalidomide Arms Versus no Thalidomide Arms

Thalidomide versus not Thalidomide analysis: Comparison of median PFS outcome of participants in arms II, VI, VII and VIII, versus participants in arms I, III, IV and V. Median PFS was estimated using the Kaplan-Meier method from time of randomization to time of progression, death, or last follow-up. Progression defined as 25% increase in the sum of products of all measurable lesions over smallest sum observed (over baseline if no decrease) using the same techniques as baseline, OR clear worsening of any evaluable disease, OR appearance of any new lesion/site, OR failure to return for evaluation due to death or deteriorating condition (unless clearly unrelated to this cancer). (NCT00112502)
Timeframe: Every 2 cycles (1 cycle = 28 days) from randomization until progression of disease, death or last follow-up, up to one year (12 study cycles).

Interventionmonths (Median)
Thalidomide: Arm II, Arm VI, Arm VII and Arm VIII7.6
No Thalidomide: Arm I, Arm III, Arm IV and Arm V8.7

Median Progression-Free Survival (PFS) of Individual Arms

Median PFS was estimated using the Kaplan-Meier method from time of randomization to time of progression, death, or last follow-up. Progression defined as 25% increase in the sum of products of all measurable lesions over smallest sum observed (over baseline if no decrease) using the same techniques as baseline, OR clear worsening of any evaluable disease, OR appearance of any new lesion/site, OR failure to return for evaluation due to death or deteriorating condition (unless clearly unrelated to this cancer). (NCT00112502)
Timeframe: Every 2 cycles (1 cycle = 28 days) from randomization until progression of disease, death or last follow-up.

Interventionmonths (Median)
Arm I: TMZ10.5
Arm II: TMZ + Thalidomide7.7
Arm III: TMZ + Celecoxib13.4
Arm IV: TMZ + Isotretinoin6.5
Arm V: TMZ + Isotretinoin + Celecoxib11.6
Arm VI: TMZ + Thalidomide + Celecoxib7.9
Arm VII: TMZ + Thalidomide + Isotretinoin6.2
Arm VIII: TMZ + Thalidomide + Isotretinoin + Celecoxib5.8

Overall Survival of Individual Arms

Overall Survival (OS) was estimated using the Kaplan-Meier method from time of randomization to time of progression, death, or last follow-up. Progression defined as 25% increase in the sum of products of all measurable lesions over smallest sum observed (over baseline if no decrease) using the same techniques as baseline, OR clear worsening of any evaluable disease, OR appearance of any new lesion/site, OR failure to return for evaluation due to death or deteriorating condition (unless clearly unrelated to this cancer). (NCT00112502)
Timeframe: Every 3 months from randomization until progression of disease, death or last follow-up.

Interventionmonths (Median)
Arm I: TMZ21.2
Arm II: TMZ + Thalidomide17.4
Arm III: TMZ + Celecoxib18.1
Arm IV: TMZ + Isotretinoin11.7
Arm V: TMZ + Isotretinoin + Celecoxib23.1
Arm VI: TMZ + Thalidomide + Celecoxib20.2
Arm VII: TMZ + Thalidomide + Isotretinoin17.9
Arm VIII: TMZ + Thalidomide + Isotretinoin + Celecoxib18.5

Maximum Tolerated Dose of MGd (Phase I)

"Patients were to be followed for a minimum of 90 days from the start of radiation therapy (RT) and carefully evaluated with respect to treatment morbidity. A dose limiting toxicity (DLT) was defined as a grade 4 neurologic adverse event (AE) considered to be related to treatment occurring within 21 days of the conclusion of RT. For each dose level, up to seven patients were to be accrued to assure that there would be six eligible for treatment adverse event evaluation. A dose level of MGd was considered acceptable if no more than 1 patient of the 6 experience a DLT. If the current level was considered acceptable, then dose escalation occurred. Otherwise, the preceding dose level would be declared the maximum tolerated dose (MTD). The MTD would be used for the Phase II arm.~Rating scale: 0 = not the MTD, 1 = MTD" (NCT00305864)
Timeframe: From start of radiation therapy to 90 days,

Interventionunits on a scale (Number)
Phase I: MGd 3 mg/kg0
Phase I: MGd 4 mg/kg0
Phase I: 5 mg/kg1

Median Overall Survival (Phase II)

Survival time was defined as the time from baseline to date of death from any cause. Patients last known to be alive are censored at date of last contact. (NCT00305864)
Timeframe: From randomization to date of death or last follow-up. Analysis occurs after all patients have been potentially followed for at least 18 months. Patients were followed up to 54.3 months

InterventionMonths (Median)
All MGd 5mg/kg Patients (Phase I and II Arms Combined)15.6

Progression-free Survival (Phase II)

Progression will be defined as a > 25% increase in tumor area. Progression-free survival time was defined as the time from baseline to date of death from any cause. Patients last known to be alive are censored at date of last contact. (NCT00305864)
Timeframe: From randomization to date of progression, death, or last follow-up. Analysis occurs after all patients have been potentially followed for at least 18 months. Patients were followed up to 54.3 months.

Interventionmonths (Median)
All MGd 5mg/kg Patients (Phase I and II Arms Combined)7.6

Median Overall Survival (OS)

Time in months from the start of study treatment to the date of death due to any cause. Patients alive as of the last follow-up had OS censored at the last follow-up date. Median OS was estimated using a Kaplan-Meier curve. (NCT00979017)
Timeframe: 36 months

Interventionmonths (Median)
Avastin in Combination With Temozolomide and Irinotecan12

Median Progression-free Survival (PFS)

Time in months from the start of study treatment to the date of first progression according to RANO criteria, or to death due to any cause. Per RANO, progression is a ≥ 25% increase in the sum of the products of perpendicular diameters of enhancing lesions, worsening T2/FLAIR, any new lesion, or clinical deterioration. Patients alive who had not progressed as of the last follow-up had PFS censored at the last follow-up date. Median PFS was estimated using a Kaplan-Meier curve. (NCT00979017)
Timeframe: 36 months

Interventionmonths (Median)
Avastin in Combination With Temozolomide and Irinotecan8.6

Response Rate

The percentage of participants with a complete or partial response as determined by a modification of the Response Assessment in Neuro-Oncology (RANO) criteria. Complete Response (CR) was defined as complete disappearance on MR/CT of all enhancing tumor and mass effect, off all corticosteroids (or receiving only adrenal replacement doses) and accompanied by a stable or improving neurologic examination. Partial Response (PR) was defined as greater than or equal to 50% reduction in tumor size on MR/CT by bi-dimensional measurement, on a stable or decreasing dose of corticosteroids and accompanied by a stable or improving neurologic examination. Per the criteria, confirmation of response was required. Response rate = CR+PR. (NCT00979017)
Timeframe: 4 months

Interventionpercentage of participants (Number)
Avastin in Combination With Temozolomide and Irinotecan22

Incidence and Severity of Central Nervous System (CNS) Hemorrhage and Systemic Hemorrhage

Incidence and severity of CNS hemorrhage and systemic hemorrhage- The adverse events for this study were collected using Common Terminology Criteria for Adverse Events (CTCAE) version 3.0, and have been converted to CTCAE version 4.0 for entry into ClinicalTrials.gov. (NCT00979017)
Timeframe: 4 months

Interventionparticipants (Number)
CNS hemorrhage (grade 3)Systemic hemorrhage (all grade 3)
Avastin in Combination With Temozolomide and Irinotecan13

Incidence of Grade ≥ 4 Hematologic and ≥ Grade 3 Non-hematologic Toxicities

Incidence of treatment-related, grade ≥ 4 hematologic and ≥ grade 3 non-hematologic toxicities- The adverse events for this study were collected using Common Terminology Criteria for Adverse Events (CTCAE) version 3.0, and have been converted to CTCAE version 4.0 for entry into ClinicalTrials.gov. (NCT00979017)
Timeframe: 4 months

Interventionparticipants (Number)
Grade > or = to 4 hematologic toxicityGrade > or = to 3 non-hematologic toxicity
Avastin in Combination With Temozolomide and Irinotecan717

12-Month Overall Survival (OS) Rate

The 12-month overall survival rate was defined as the percentage of participants surviving at 12 months. The distribution of 12-month OS rate was estimated using Kaplan-Meier methodology. Point estimates and 95% CIs for the quartiles for the PFS distribution are provided. Per protocol, because neither the ABT-888 20 mg BID + TMZ nor ABT-888 40 mg BID + TMZ treatment groups were statistically significantly better than the Placebo + TMZ treatment group for the primary endpoint of PFS, confirmatory statistical testing was not continued for any secondary endpoints, regardless of the observed P values. (NCT00804908)
Timeframe: Per protocol, survival was to be assessed every 4 weeks or as needed after participant is registered as off-study for up to 18 months. The maximum observed follow-up at the overall survival analysis time was 21.0 months.

Interventionpercentage of participants (Number)
Placebo for ABT-888 BID + TMZ QD52.6
ABT-888 20 mg BID + TMZ QD43.5
ABT-888 40 mg BID + TMZ QD54.1

6-month Progression-Free Survival Rate

The 6-month progression-free survival rate was defined as the percentage of participants without disease progression at 6 months.The distribution of 6-month progression-free survival rate, as determined by the central imaging center (radiological)/ investigator (clinical), was estimated using Kaplan-Meier methodology. Point estimates and 95% CIs for the quartiles for the PFS distribution are provided. Per protocol, because neither the ABT-888 20 mg BID + TMZ nor ABT-888 40 mg BID + TMZ treatment groups were statistically significantly better than the Placebo + TMZ treatment group for the primary endpoint of PFS, confirmatory statistical testing was not continued for any secondary endpoints, regardless of the observed P values. (NCT00804908)
Timeframe: Every Cycle (28 Days) until disease progression was observed or another reason for discontinuation of assessments was identified by the investigator. The maximum observed followup duration at the progression-free survival analysis time was 9.7 months.

Interventionpercentage of participants (Number)
Placebo for ABT-888 BID + TMZ QD19.1
ABT-888 20 mg BID + TMZ QD32.8
ABT-888 40 mg BID + TMZ QD30.7

Disease Control Rate

The disease control rate was defined as the percentage of participants who had at least stable disease (complete response, partial response, or stable disease) through the end of Week 8. Per protocol, because neither the ABT-888 20 mg BID + TMZ nor ABT-888 40 mg BID + TMZ treatment groups were statistically significantly better than the Placebo + TMZ treatment group for the primary endpoint of PFS, confirmatory statistical testing was not continued for any secondary endpoints, regardless of the observed P values. (NCT00804908)
Timeframe: Week 8

Interventionpercentage of participants (Number)
Placebo for ABT-888 BID + TMZ QD48.7
ABT-888 20 mg BID + TMZ QD62.9
ABT-888 40 mg BID + TMZ QD59.1

Objective Response Rate

The objective response rate was defined as the percentage of participants with a confirmed CR or PR per Response Evaluation Criteria In Solid Tumors Criteria (RECIST v1.0) for target lesions and assessed by computed tomography (CT) scan: complete response (CR), disappearance of all target lesions; partial response (PR), ≥30% decrease in the sum of the longest diameter of target lesions; Overall Response (OR) = CR + PR. Per protocol, because neither the ABT-888 20 mg BID + TMZ nor ABT-888 40 mg BID + TMZ treatment groups were statistically significantly better than the Placebo + TMZ treatment group for the primary endpoint of PFS, confirmatory statistical testing was not continued for any secondary endpoints, regardless of the observed P values. (NCT00804908)
Timeframe: Every 2 cycles (8 weeks) until disease progression was observed or another reason for discontinuation of assessments was identified by the investigator. The maximum observed followup duration at the progression-free survival analysis time was 9.7 months.

Interventionpercentage of participants (Number)
Placebo for ABT-888 BID + TMZ QD7.0
ABT-888 20 mg BID + TMZ QD10.3
ABT-888 40 mg BID + TMZ QD9.6

Overall Survival (OS): Time to Event

OS was defined as the number of days from the date the participant was randomized to the date of death. All deaths were included, whether the participant was still taking or had discontinued study drug. If a participant had not died and was lost to follow-up, then data were censored at the last study visit or contact date, or date the participant was last known to be alive, whichever was later; if the participant was not lost to follow-up, then data were censored at the last study visit or contact date, whichever was later. The distribution of OS was estimated for each treatment group using Kaplan-Meier methodology. Point estimates and 95% CIs for the quartiles for the OS distribution are provided. Per protocol, because neither the ABT-888 20 mg BID + TMZ nor ABT-888 40 mg BID + TMZ groups were statistically significantly better than the Placebo + TMZ group for the primary endpoint of PFS, confirmatory statistical testing was not continued for any secondary endpoints. (NCT00804908)
Timeframe: Per protocol, survival follow-up information was to be obtained every 3 months for up to 18 months after the final visit for the subject. The maximum observed follow-up at the overall survival analysis time was 21.0 months.

,,
Interventiondays (Number)
25th Percentile50th percentile75th percentile
ABT-888 20 mg BID + TMZ QD204327NA
ABT-888 40 mg BID + TMZ QD181412NA
Placebo for ABT-888 BID + TMZ QD207390559

Progression-Free Survival (PFS): Time to Event

PFS: the number of days from the date that the participant was randomized to the date the participant experienced a confirmed event of disease progression (radiological, as determined by the central imaging center; or clinical, as determined by the investigator), or to the date of death (all causes of mortality) if disease progression was not reached. All events were included whether the participant was still taking or had discontinued study drug. Events of death were included for participants who had not experienced a confirmed event of disease progression, provided the death occurred within 8 weeks of the last available disease progression assessment. The distribution of PFS, as determined by the central imaging center (radiological)/ investigator (clinical), was estimated for each treatment group using Kaplan-Meier methodology. Point estimates and 95% confidence intervals (95% CIs) for the quartiles for the PFS distribution are provided. (NCT00804908)
Timeframe: Every Cycle (28 Days) until disease progression was observed or another reason for discontinuation of assessments was identified by the investigator. The maximum observed followup duration at the progression-free survival analysis time was 9.7 months.

,,
Interventiondays (Number)
25th Percentile50th Percentile75th Percentile
ABT-888 20 mg BID + TMZ QD56113225
ABT-888 40 mg BID + TMZ QD53110226
Placebo for ABT-888 BID + TMZ QD5460163

Time to Disease Progression

The distribution of time to disease progression, as determined by the central imaging center (radiological)/ investigator (clinical), was estimated for each treatment group using Kaplan-Meier methodology. Point estimates and 95% CIs for the quartiles for the PFS distribution are provided. Per protocol, because neither the ABT-888 20 mg BID + TMZ nor ABT-888 40 mg BID + TMZ treatment groups were statistically significantly better than the Placebo + TMZ treatment group for the primary endpoint of PFS, confirmatory statistical testing was not continued for any secondary endpoints, regardless of the observed P values. (NCT00804908)
Timeframe: Every Cycle (28 Days), until disease progression was observed or another reason for discontinuation of assessments was identified by the investigator. The maximum observed followup duration at the progression-free survival analysis time was 9.7 months.

,,
Interventiondays (Number)
25th Percentile50th percentile75th percentile
ABT-888 20 mg BID + TMZ QD56113225
ABT-888 40 mg BID + TMZ QD53110226
Placebo for ABT-888 BID + TMZ QD5460163

Time to Neurological/Brain Metastases Progression

Time to neurological/brain metastases progression, defined as the number of days from the date of randomization to the date the participant experienced an event of neurological/brain metastases progression, was estimated using Kaplan-Meier methodology. Point estimates and 95% CIs for the quartiles for the distribution are provided. All events of progression were included, regardless of whether the event occurred while the participant was still taking study drug. If a participant did not experience an event, data were censored at the date of the last available brain CT scan. For participants with no postbaseline brain CT scans, data were censored at randomization. Per protocol, because neither the ABT-888 20 mg BID + TMZ nor ABT-888 40 mg BID + TMZ groups were statistically significantly better than the Placebo + TMZ group for the primary endpoint of PFS, confirmatory statistical testing was not continued for any secondary endpoints, regardless of the observed P values. (NCT00804908)
Timeframe: Every 2 cycles (8 weeks) until disease progression was observed or another reason for discontinuation of assessments was identified by the investigator. The maximum observed followup duration at the progression-free survival analysis time was 9.7 months.

,,
Interventiondays (Number)
25th Percentile50th percentile75th percentile
ABT-888 20 mg BID + TMZ QD119NANA
ABT-888 40 mg BID + TMZ QD184184NA
Placebo for ABT-888 BID + TMZ QD60NANA

Overall Survival

Patients were monitored until death (NCT00187486)
Timeframe: assessment of survival was every 2 months, up to 181 weeks

Interventionmonths (Median)
Temodar Plus Tarceva Plus Radiotherapy19

Progression Free Survival

Progression based on MR imaging using the Modified McDonnald Criteria defined as 25% increase in sum of products of all measured lesions or any new lesion (NCT00187486)
Timeframe: every 2 months measure by MR imaging, up to 39 months

Interventionmonths (Median)
Temodar Plus Tarceva Plus Radiotherapy8.2

Safest Dose of Temozolomide for the DRBEAT Regimen

Safety will be assessed using a dose escalation design for temozolomide's use to determine the target dose and also to evaluate any and all acute treatment related toxicities. During the course of patient follow up and therapy, toxicities will be evaluated, particularly as the investigators will be determining the target dose of temozolomide. One of the major criteria for dose limiting toxicity for the study will be any Grade 3 or 4 nonhematologic toxicity from a list of commonly expected toxicities associated with autologous transplantation and temozolomide. (NCT01235793)
Timeframe: One Year

Interventiondose in mg/m^2 (Number)
DRBEAT Regimen773.25

One-year Progression-free Survival and Overall Survival

"Efficacy of the DRBEAT Regimen will be assessed by analysis of~one-year progression-free survival (PFS), defined as the time interval from maximal response from therapy to tumor regrowth, progression*, or death, (*Progression is defined as meeting the response criteria listed in Table 4: Response Criteria for Primary Central Nervous System Lymphoma according to Abrey LE, Batchelor TT, Ferreri AJM et al.)~and~Overall survival, defined as the time interval between the date of transplant and the date of death from any cause." (NCT01235793)
Timeframe: (1) One Year (2) Until date of death from any cause, assessed up to 2 years

InterventionDays (Median)
Progression Free SurvivalOverall Survival
DRBEAT Regimen132564

Percentage of Participants Surviving at Six Months of Treatment Without Evidence of Disease Progression.

Progression-free survival as determined by Kaplan-Meier method. (NCT00392171)
Timeframe: 6 months

InterventionPercentage of Participants (Number)
Anaplastic Glioma (n=28)Early Glioblastoma Multiforme (GBM) (n=33)Extended Glioblastoma Multiforme (GBM) (n=27)Rechallenge Glioblastoma Multiforme (GBM) (n=28)
Temozolomide35.727.37.435.7

6 Month Progression Free Survival (PFS)

Percentage of participants surviving six months from the start of study treatment without progression of disease. PFS was defined as the time from the date of study treatment initiation to the date of the first documented progression according to the Macdonald criteria, or to death due to any cause. (NCT00597493)
Timeframe: 6 months

Interventionpercentage of patients (Number)
Sorafenib + Temozolomide9.4

Pharmacokinetics: AUC-24

Blood sampling for sorafenib pharmacokinetics was performed on days 1 and 28 of cycle 1 and was obtained before and at 0.5, 1, 2, 4, 6, 8, and 24 h after the morning dose. AUC-24 refers to area under the plasma concentration-time curve from 0 to 24 hours. The pharmacokinetics of those patients taking enzyme-inducing antiepileptic drugs (EIAEDs) and those who were not were analyzed separately. (NCT00597493)
Timeframe: 13 months

Interventionug*H/L (Geometric Mean)
EIAEDs-Day 145309.7
EIAEDs-Day 2847148.2
Non-EIAEDs-Day 145238.7
Non-EIAEDs-Day 28128820.8

Pharmacokinetics: C-max

Blood sampling for sorafenib pharmacokinetics was performed on days 1 and 28 of cycle 1 and was obtained before and at 0.5, 1, 2, 4, 6, 8, and 24 h after the morning dose. C-max refers to maximum plasma concentration. The pharmacokinetics of those patients taking enzyme-inducing antiepileptic drugs (EIAED) and those who were not were analyzed separately. (NCT00597493)
Timeframe: 13 months

Interventionug/L (Geometric Mean)
EIAEDs-Day 13397.3
EIAEDs-Day 283813.9
Non-EIAEDs-Day 13155.1
Non-EIAEDs-Day 288118.8

Pharmacokinetics: T-max

Blood sampling for sorafenib pharmacokinetics was performed on days 1 and 28 of cycle 1 and was obtained before and at 0.5, 1, 2, 4, 6, 8, and 24 h after the morning dose. T-max refers to time to maximum concentration. The pharmacokinetics of those patients taking enzyme-inducing antiepileptic drugs (EIAED) and those who were not were analyzed separately. (NCT00597493)
Timeframe: 13 months

Interventionhours (Median)
EIAEDs-Day 18.2
EIAEDs-Day 282.1
Non-EIAEDs-Day 124.0
Non-EIAEDs-Day 284.2

Safety and Toxicity of Combination

Number of participants experiencing a toxicity of at least grade 3 that was deemed possibly, probably, or definitely related to the treatment. (NCT00597493)
Timeframe: 16 months

Interventionparticipants (Number)
Sorafenib + Temozolomide19

Objective Response

"The number of patients with complete or partial responses measured from the time of initial response to documented tumor progression. Radiologic response was defined using the Macdonald criteria.~The Macdonald criteria divides response into 4 types of response based on imaging (MRI) and clinical features, as follows: 1) complete response (CR); 2) partial response (PR); 3) stable disease (SD); and 4) progression (PD).~Criteria:~CR: disappearance of all enhancing disease (measurable and non-measurable) sustained for at least 4 weeks, no new lesions. No corticosteroids, clinically stable or improved.~PR: >=50% decrease of all measurable enhancing lesions, sustained for at least 4 weeks, no new lesions. Stable or reduced corticosteroids, clinically stable or improved.~SD: does not qualify for complete response, partial response or progression. Clinically stable.~PD: >= 25% increase in enhancing lesions, any new lesions. Clinical deterioration." (NCT00544817)
Timeframe: every 8 weeks until disease progression, estimated 18 months

Interventionparticipants (Number)
Combination Therapy13

Overall Survival

Defined as Day 1 of protocol treatment to date of death from any cause. (NCT00544817)
Timeframe: 18 months

InterventionMonths (Median)
Combination Therapy12

Progression-free Survival

Defined as the duration of time from start of treatment to time of progression or death, whichever comes first. (NCT00544817)
Timeframe: 18 months

InterventionMonths (Median)
Combination Therapy6

Survival

survival time is defined from time of histological diagnosis to death occurrence. (NCT00262730)
Timeframe: 30 months

Interventionmonths (Mean)
Treatment Arm - All Subjects17.2

Overall Survival in Treated Patients

Patients who are alive on the date of closing follow-up, or 30 months after completing all study treatments, will be censored on that date (NCT01984892)
Timeframe: up to 30 months

InterventionParticipants (Count of Participants)
Participants With Stage 4 Cancer8

Progression-free Survival

"Progression-free survival defined as the time in weeks from study entry until tumor progression defined using the Wolchok criteria or death. Patients who are alive and free from progression on the date of closing follow-up will be censored on that date.~In order to minimize the potential for misdiagnosis of pseudoprogression, related to early inflammation, tumor measurement for determination of progression will be made at the earliest at 26 weeks." (NCT01984892)
Timeframe: average 52 weeks

Interventionweeks (Number)
Participants With Stage 4 Cancer41

Maximum Tolerated Dose (MTD) of Everolimus (RAD001) in Combination With Temozolomide (TMZ) and 3D-conformal Radiotherapy (RT) or Intensity-modulated Radiotherapy (IMRT) Followed by Adjuvant TMZ With or Without RAD001 (Phase I)

Patients were assessed during RT for dose-limiting toxicities (DLT), which were defined as failure to deliver greater than 75% of the planned doses of TMZ or RAD001 during RT, interruption of RT for more than 5 days because of toxicity, or the following: >= Grade 3 diarrhea or skin rash; >= Grade 4 neutropenia, leukopenia, or thrombocytopenia; >= Grade 4 hypertriglyceridemia, hypercholesterolemia, or hyperglycemia despite optimal medial management, other >= 3 non-hematologic events; or >= Grade 4 radiation dermatitis. Maximum tolerated dose (MTD) was defined a priori as the highest dose level at which 0 or 1 of 6 patients developed DLTs. The number of patients who developed DLTs are reported here by dose level, with the MTD reported in the statistical analysis section. (NCT00553150)
Timeframe: Up to 49 days

Interventionparticipants who developed DLTs (Number)
Phase I: Dose Level 01
Phase I: Dose Level 11
Phase I: Dose Level 21

Overall Survival at 12 Months (Phase II)

"The primary endpoint is overall survival at 12 months (OS12) after entry into this study. The proportion of successes will be estimated using the binomial point estimator (number of successes divided by the total number of evaluable patients) and the binomial 95% confidence interval estimated. A patient who is evaluable and survive more than 12 months (i.e. 365 days or more) after start of therapy will be classified as a success. Patients who die within 12 months after start of therapy will be considered to have failed." (NCT00553150)
Timeframe: at 12 months

Interventionproportion of participants (Number)
Phase II0.64

Overall Survival Time

Overall survival: The overall survival or survival time is defined as the time from registration to death due to any cause. The distribution of overall survival will be estimated using the method of Kaplan-Meier method. (NCT00553150)
Timeframe: Up to 15 years

Interventionmonths (Median)
Phase II15.8

Progression-free-survival at 6 Months (Phase II)

Progression-free-survival at 6 months: is the proportion of patients alive and progression-free at 6 months after start of regimen. This proportion will be estimated using the binomial point estimator and the binomial 95% confidence interval estimated. Progression is defined as at least a 25% increase in product of perpendicular diameters of contrast enhancement or mass or unequivocal increase in size of contrast enhancement or increase in mass effect as agreed upon independently by primary physician and quality control physicians or appearance of new lesions. (NCT00553150)
Timeframe: at 6 months

Interventionproportion of participants (Number)
Phase II0.52

Response Rate, as Measured in Patients Receiving FLT-PET Imaging (Phase II)

The response rate is defined as the percentage of patients receiving F-fluorothymidine positron emission tomography (FLT-PET) imaging whose cancer shrinks or disappears after treatment. A reduction in standardized uptake value (SUV) of 30% or greater in the T1-post-gadolinium scan volume of interest (T1-gad VOI) or the total tumor VOI will be considered a responsive tumor. (NCT00553150)
Timeframe: Up to 5 years

Interventionpercentage of participants (Number)
Phase II44.4

Time to Progression (Phase II)

Time-to-disease progression is defined as the time from start of study therapy to documentation of disease progression. Patients who die without documentation of progression will be considered to have had tumor progression at the time of death unless there is documented evidence that no progression occurred before death. Patients who fail to return for evaluation after beginning therapy will be censored for progression on the last day of therapy. Patients who experience major treatment violations will be censored for progression on the date of treatment violation occurred. The time-to-progression distribution will be estimated using the Kaplan-Meier method. Progression is defined as at least a 25% increase in product of perpendicular diameters of contrast enhancement or mass or unequivocal increase in size of contrast enhancement or increase in mass effect as agreed upon independently by primary physician and quality control physicians or appearance of new lesions. (NCT00553150)
Timeframe: Up to 5 years

Interventionmonths (Median)
Phase II6.4

Clinical Efficacy of Vaccination, in Terms of Progression-free Survival (PFS)

"Time in months from the start of study treatment to the date of first progression according to Macdonald criteria, or to death due to any cause. Patients alive who had not progressed as of the last follow-up had PFS censored at the last follow-up date. Median PFS was estimated using a Kaplan-Meier curve.~Macdonald criteria are standard criteria in neuro-oncology. Tumor assessment was made according to the adapted MacDonald criteria based on the combined evaluation of: 1) assessment of the MRI scan for measurable, evaluable, and new lesions (made by the independent external expert too), 2) overall assessment of neurological performance (made by the investigator), 3) concomitant steroid use (as reported by the investigator)." (NCT00643097)
Timeframe: 58 months

Interventionmonths (Median)
Arm I (ACTIVATE)14.2
Arm II (ACT II STD)12.1
Arm III (ACT II DI)11.6

Humoral and Cellular Immune Response

Number of patients that developed a delayed-type hypersensitivity (DTH) response at following vaccination. Any skin reaction in response to the intradermal injection of the antigen was measured and recorded. A positive skin test was defined as > 5 mm induration (swelling). (NCT00643097)
Timeframe: 26 months

Interventionparticipants (Number)
Arm I (ACTIVATE)3
Arm II (ACT II STD)0
Arm III (ACT II DI)7

Response to Vaccination

The objective is to assess the duration of immunosuppressive cytokine secretion and to identify a receptive interval for active immunotherapy. Immunosuppression will determined by monitoring a panel of immunosuppressive serum/plasma cytokines longitudinally and by determining the response of each patient to Recombivax Hepatitis B (HB) vaccination. Response is defined as seropositive or seronegative to the Hepatitis B surface antigen. (NCT00643097)
Timeframe: 26 months

InterventionMonths (Mean)
Arm I (ACTIVATE)NA
Arm II (ACT II STD)NA
Arm III (ACT II DI)NA

Toxicity to PEP-3 Vaccine Immunization

To assess for any potential toxicity to the PEP-3 vaccine immunization in patients with newly diagnosed glioblastoma, Common Terminology Criteria for Adverse Events (CTCAE) version 3.0 was used to tabulate any toxicities attributable to PEP-3. The number of patients with toxicity attributable to vaccine while on study are tabulated. (NCT00643097)
Timeframe: 26 months

Interventionparticipants (Number)
Arm I (ACTIVATE)4
Arm II (ACT II STD)1
Arm III (ACT II DI)7

Overall Survival

all patients alive as of the last contact were censored for survival on the basis of that contact date (NCT00369590)
Timeframe: 3 years

Interventionweeks (Median)
Arm I - Anaplastic Glioma55
Arm 2 - Glioblastoma39

Progression Free Survival (PFS) Rate for Subjects With Radiographic Response

"pts with confirmed radiographic response and their rate of progression (PFS).~Response determined by modified MacDonald Criteria Complete Response (CR): Complete disappearance of all measurable and evaluable disease, no new lesions. no steroids Partial Response (PR): Greater than or equal to 50% decrease under baseline in the sum of products of perpendicular diameters of all measurable lesions. No progression of evaluable lesions. no new lesions. steroid dose no > than maximum dose used in first 8 weeks of treatment.~Stable: Does not qualify for CR, PR, or progression steroid dose no > than maximum dose used in first 8 weeks of treatment.~Progression: 25% increase in the sum of products of all measurable lesions over smallest sum observed (over baseline if no increase) Clear clinical worsening." (NCT00369590)
Timeframe: up to 3 years

Interventionweeks (Median)
Arm I - Anaplastic Glioma45
Arm 2 - Glioblastoma23

Progression-free Survival (PFS) at 6 Months

"This design yields 85% power to detect a true 30% 6-month PFS rate, while maintaining .91 probability of rejecting for a true 15% 6-month PFS rate.~pts had MRIs at screening and at the 3rd and 5th cycles then every 8 weeks until progression.~Response determined by modified MacDonald Criteria Complete Response (CR): Complete disappearance of all measurable and evaluable disease, no new lesions. no steroids Partial Response (PR): Greater than or equal to 50% decrease under baseline in the sum of products of perpendicular diameters of all measurable lesions. No progression of evaluable lesions. no new lesions. steroid dose no > than maximum dose used in first 8 weeks of treatment.~Stable: Does not qualify for CR, PR, or progression steroid dose no > than maximum dose used in first 8 weeks of treatment.~Progression: 25% increase in the sum of products of all measurable lesions over smallest sum observed (over baseline if no increase) Clear clinical worsening." (NCT00369590)
Timeframe: 6 months

Interventionpercentage of participants (Number)
Arm I - Anaplastic Glioma25
Arm 2 - Glioblastoma7.7

Safety Profile - Events That Discontinued Treatment

number of patients who experienced toxicity that led to being taken off treatment (NCT00369590)
Timeframe: Approximately 1 year (start of treatment - end of treatment)

Interventionparticipants (Number)
Arm I - Anaplastic Glioma8
Arm 2 - Glioblastoma6

Safety Profile - Toxicities

number of cycles patient was able to have before developing a toxicity that required removing the patient from treatment. Treatment: Aflibercept 4mg/kg intravenously on day 1 of every 14-day cycle - 2 week cycle. (NCT00369590)
Timeframe: Start to End of treatment 39 cycles or 1yr 7.5months (78 weeks)

Interventioncycles (Median)
Arm I - Anaplastic Glioma5
Arm 2 - Glioblastoma3.5

Response Rate Associated With VEGF Trap Therapy Defined as Proportions of Patients Experiencing Complete or Partial Response

"pts had MRIs at screening and at the 3rd and 5th cycles then every 8 weeks until progression. All responders were centrally reviewed for confirmation~Response determined by modified MacDonald Criteria Complete Response (CR): Complete disappearance of all measurable and evaluable disease, no new lesions. no steroids Partial Response (PR): Greater than or equal to 50% decrease under baseline in the sum of products of perpendicular diameters of all measurable lesions. No progression of evaluable lesions. no new lesions. steroid dose no > than maximum dose used in first 8 weeks of treatment.~Stable: Does not qualify for CR, PR, or progression steroid dose no > than maximum dose used in first 8 weeks of treatment.~Progression: 25% increase in the sum of products of all measurable lesions over smallest sum observed (over baseline if no increase) Clear clinical worsening." (NCT00369590)
Timeframe: Up to 2 years

,
Interventionparticipants (Number)
Complete ResponsePartial Response
Arm 2 - Glioblastoma07
Arm I - Anaplastic Glioma16

6-Month Progression-free Survival

Percentage of participants surviving six months from the start of study treatment without progression of disease. PFS was defined as the time from the date of study treatment initiation to the date of the first documented progression according to the Macdonald criteria, or to death due to any cause. [Optional: Macdonald criteria are standard criteria in neuro-oncology. Tumor assessment was made according to the adapted MacDonald criteria based on the combined evaluation of: 1) assessment of the MRI scan for measurable, evaluable, and new lesions (made by the independent external expert too), 2) overall assessment of neurological performance (made by the investigator), 3) concomitant steroid use (as reported by the investigator).] (NCT00501891)
Timeframe: 6 months

Interventionpercentage of participants (Number)
Bevacizumab and Metronomic Temozolomide18.8

Response Rate

The number of participants with complete or partial response as determined by a modification of the Macdonald criteria. Complete response was defined as complete disappearance on MR/CT of all enhancing tumor and mass effect, off all corticosteroids (or receiving only adrenal replacement doses), accompanied by a stable or improving neurologic examination, and maintained for at least 4 weeks. Partial Response was defined as greater than or equal to 50% reduction in tumor size on MR/CT by bi-dimensional measurement, on a stable or decreasing dose of corticosteroids, accompanied by a stable or improving neurologic examination, and maintained for at least 4 weeks. (NCT00501891)
Timeframe: 27 months

InterventionNumber of participants (Number)
Bevacizumab and Metronomic Temozolomide9

Incidence and Severity of CNS Hemorrhage and Systemic Hemorrhage

Number of participants experiencing a Central Nervous System (CNS) hemorrhage or systemic hemorrhage (NCT00501891)
Timeframe: 27 months

Interventionparticipants (Number)
CNS HemorrhageSystemic Hemorrhage
Bevacizumab and Metronomic Temozolomide00

Incidence of Grade ≥ 4 Hematologic or Grade ≥ 3 Non-hematologic Toxicity

Number of participants experiencing a grade ≥4 hematologic or grade ≥3 non-hematologic toxicity (NCT00501891)
Timeframe: 27 months

Interventionparticipants (Number)
Grade ≥ 4 hematologic toxicitiesGrade ≥ 3 non-hematologic toxicities
Bevacizumab and Metromonic Temozolomide014

Objective Response Rates. Assessed With Cranial MRI

"Objective Response (OR) encompassed the number of participants with Complete Response (CR) and the number of participants with Partial Response (PR). CR is the disappearance of all brain metastases, assessed between two or more cranial MRI. PR is at least a 30% decrease in the sum of the longest diameter of the brain metastases, taking as reference the baseline sum longest diameter, assessed between two or more cranial MRI.~Objective Response Rate (ORR) is the ratio between the number of participants with objective response and the total number of participants." (NCT01015534)
Timeframe: 90 days

InterventionPercentage of participants with OR (Number)
Whole Brain Irradiation and Temozolomide78.6
Whole Brain Irradiation48.1

Overall Survival

Overall survival:Time in months measured from treatment initiation until the date of death or the date of last follow-up. (NCT01015534)
Timeframe: 1 year

InterventionMonths of Overall Survival (Median)
Whole Brain Irradiation and Temozolomide8
Whole Brain Irradiation8.1

Survival Free of Brain Metastases Progression (PFS of BM)

Progression free survival of brain metastases is the survival of participants without progressive brain metastases or without neurological symptoms. The progressive brain metastases (PBM) were evaluated with cranial MRI. The PBM were defined as an increase of at least 20% in the sum of the longest diameter of target lesions, taking as reference the smallest sum longest diameter recorded since the treatment started or the appearance of one or more new metastases. (NCT01015534)
Timeframe: at 90 days

InterventionPercentage of Participants (Number)
Whole Brain Irradiation and Temozolomide88.7
Whole Brain Irradiation83.7

Number of Grade 3-4 Adverse Events (AE) That Are Definitely or Probably Related to Both Groups of Treatment.

"AE, evaluated and graded according to the NCI common terminology criteria (NCI-CTCAE) v3.0~Grade 3 Severe AE.~Grade 4 Life-threatening or disabling AE." (NCT01015534)
Timeframe: 4 months

,
InterventionEvents (Number)
LeukopeniaLymphopeniaNausea-VomitingNeutropeniaPlatelets
Whole Brain Irradiation06010
Whole Brain Irradiation and Temozolomide111113

Progression Free Survival (PFS)

Progression free survival is defined by any of the following: ≥ 25% increase in sum of the products of perpendicular diameters of enhancing lesions (compared with baseline if no decrease) on stable or increasing doses of corticosteroids; a significant increase in T2/FLAIR non-enhancing lesions on stable or increasing dose of corticosteroids compared with baseline scan or best response after initial of therapy, not due to comorbid events; the appearance of any new lesions; clear progression of non-measurable lesions; or definite clinical deterioration not attributable to another causes apart from the tumor, or to decrease in corticosteroid dose. (NCT02082119)
Timeframe: 1 year

InterventionParticipants (Count of Participants)
High Grade Glioma82

Dose Limiting Toxicities of EMD + RT and TMZ

"pts will be evaluated from first dose through end of initiation cycle. (6 weeks of RT+TMZ +EMD and 4 weeks of EMD alone) to review dose limiting toxicity (DLT) using Common Terminology Criteria for Adverse Events (CTCAE) version 4.0 (Phase I)~DLT defined as: Known TMZ hematological toxicities will not be considered dose limiting.~Nonhematological toxicities Grades 3-4 severity (except nausea and vomiting without sufficient antiemetic prophylaxis)" (NCT00085254)
Timeframe: 10 weeks

Interventionparticipants (Number)
Arm 1 500mg (Safety Run In)0
ARM 2 1000mg (Safety run-in)0
Arm 3 2000mg (Safety Run-In)0

Frequency of Hematologic and Nonhematologic Adverse Events

The proportion of patients with grade 3 and grade 4 hematologic and non hematologic adverse events per CTCAE 4.0 (NCT00085254)
Timeframe: Up to 1 year

InterventionNumber of grade 3 or 4 events (Number)
Arm 1- Phase 2 (500mg)48
Arm 2 - Phase 2 (2000mg)35

Maximum Tolerated or Tolerable Dose (MTD) - 3 Pre-defined Doses

"pts will be evaluated from first dose through end of initiation cycle. (6 weeks of RT+TMZ +EMD and 4 weeks of EMD alone) to review any dose limiting toxicity (DLT) using Common Terminology Criteria for Adverse Events (CTCAE) version 4.0 (safety run-in)~DLT defined as: Known TMZ hematological toxicities will not be considered dose limiting.~cohorts at these 3 defined doses: 500mg, 1000mg and 2000mg MTD defined as: dose producing DLT in 2 out of 6 patients or dose level below the dose which produced DLT in >/= 2 out of 3 patients, or in >/= 3 out of 6 patients If no MTD (maximum tolerable dose) was defined through 3 steps of dose escalation, phase 2 will proceed with a randomized treatment allocation of the two pre-specified dosage arms: low dose; 500mg and high dose; 2000mg" (NCT00085254)
Timeframe: 10 weeks

Interventionmg (Number)
Arm 1 - Safety Run InNA

Overall Survival (Phase II)

The overall survival is calculated from time of histological diagnosis to death occurance - median based on all 112 patients, all dose levels (NCT00085254)
Timeframe: up to 36 months

Interventionmonths (Median)
Arm 4 (Overall Study)19.7

Overall Survival Based on Dose Level - Phase 2

survival calculated from date of initial histologic diagnosis and occurence of death. Pts at 500mg dose compared against Pts treated at 2000mg dose. Calculated using median (NCT00085254)
Timeframe: Up to 3 years

Interventionmonths (Median)
Arm 1 - Phase 2 (Treatment 1)17.4
Arm 2 - Phase 2 (Treatment 2)20.8

Number of Participants Experiencing Toxicity After This Novel Multimodality Regimen

The toxicity assessments were made according to the common terminology criteria for adverse events (CTCAE version 3.0) of the National Cancer Institute. Number of participants with Grade 1 to 5 adverse events are reported here. (NCT00805961)
Timeframe: 18 months

InterventionParticipants (Count of Participants)
Overall Study53

Objective Response Rate of Patients With Glioblastoma Multiforme Following Treatment With This Novel Multimodality Regimen

Response to treatment was assessed by MRI using the MacDonald criteria based on the assessment of the MRI scan for measurable, evaluable, and new lesions. The objective response rate is defined as the proportion of patients with improvement and or decreased extent of lesions compared to baseline. (NCT00805961)
Timeframe: 18 months

InterventionParticipants (Count of Participants)
Overall Study31

Overall Survival of Patients With Glioblastoma Multiforme Following Treatment With This Novel Multimodality Regimen

Overall survival was defined as the interval from the first day of study treatment until the date of death. (NCT00805961)
Timeframe: 18 months

InterventionMonths (Number)
Overall Study13.9

Progression-free Survival (PFS)

Progression-free survival is defined as the duration of time from start of treatment to time of progression or death, whichever comes first. (NCT00805961)
Timeframe: 18 months

InterventionMonths (Median)
Overall Study11.3

Change in Body Fat Measurement

Analyzed via a paired t-test. Change in body fat measurement as determined by the Durnin-Womersley 4-fold technique (NCT01819233)
Timeframe: Baseline to 4 weeks after completion of study

Interventionpercentage of change in body fat (Mean)
Behavioral Dietary Intervention-3.1

Change in Body Mass Index (BMI)

Assessed via mixed-effects regression. Weight changes over time assessed by modeling BMI as a function of time (NCT01819233)
Timeframe: Baseline to 4 weeks after completion of study

Interventionpercentage of change in BMI (Mean)
Behavioral Dietary Intervention-1.2

Change in Heart Rate Over Time

Assessed via mixed-effects regression. (NCT01819233)
Timeframe: Baseline to 4 weeks after completion of study

Interventionbeats per minute (Mean)
Behavioral Dietary Intervention67.3

Distant Metastases

Analyzed via survival methods, specifically the Kaplan-Meier method and the logrank test. (NCT01819233)
Timeframe: Up to 4 weeks after completion of study

InterventionParticipants (Count of Participants)
Behavioral Dietary InterventionNA

Local Recurrence

Analyzed via survival methods, specifically the Kaplan-Meier method and the logrank test. (NCT01819233)
Timeframe: Up to 4 weeks after completion of study

InterventionParticipants (Count of Participants)
Behavioral Dietary InterventionNA

Number of Participants Who Are Adherent to the Diet Restriction

Computed along with a 95% exact confidence interval. Exact binomial test (with a one-sided alpha of 0.05) will be used to test whether adherence is greater than 60%. (NCT01819233)
Timeframe: Up to week 12

Interventionparticipants (Number)
Behavioral Dietary Intervention28

Overall Survival

Analyzed via survival methods, specifically the Kaplan-Meier method and the logrank test. (NCT01819233)
Timeframe: Up to 4 weeks after completion of study

InterventionParticipants (Count of Participants)
Behavioral Dietary InterventionNA

Patterns of Change Over Time in Psycho-social Outcomes Measured Using the Functional Assessment of Cancer Therapy-Breast (FACT-B)

Assessed via mixed-effects regression. The FACT-B is a questionnaire using a 5-point Likert scale (0-Not at all to 4-Very much) (NCT01819233)
Timeframe: Baseline to 4 weeks after completion of study

Interventionscore on a scale (Mean)
Behavioral Dietary Intervention0.8

Progression Free Survival

Analyzed via survival methods, specifically the Kaplan-Meier method and the logrank test. (NCT01819233)
Timeframe: Up to 4 weeks after completion of study

InterventionParticipants (Count of Participants)
Behavioral Dietary InterventionNA

Overall Survival

All patients will have their tumor measurements recorded at baseline and at the time of each MRI scan. Lesions must be measured in two dimensions. The dose of gadolinium must be held constant from scan to scan. Macdonald criteria will be used for assessment of tumor response. (NCT00498927)
Timeframe: 2 years

Interventionmonths (Median)
Temozolomide7

Progression-free Survival (PFS) Rate at 6 Months

Progression is defined using Response Evaluation Criteria In Solid Tumors Criteria (RECIST v1.0), as a 20% increase in the sum of the longest diameter of target lesions, or a measurable increase in a non-target lesion, or the appearance of new lesions. (NCT00498927)
Timeframe: at 6 months

Interventionpercentage of participants (Number)
Temozolomide19

Progression Free Survival PPX/RT Versus TMZ/RT for Patients With GBM Without Methylation

"MRI response evaluated by RANO criteria~Complete Response (CR): Circumstance when the enhancing tumor is no longer seen by neuroimaging, with the patient off all steroids or on adrenal maintenance only; CR will be coded only if confirmed by a second CT/MR scan performed a minimum of 4 weeks after the initial scan coding a response.~Partial Response (PR): Decrease of > 50% in the product of two diameters. Patients should be receiving stable or decreasing doses of steroids. PR will be coded only if confirmed by a second CT/MR scan performed a minimum of 4 weeks after the initial scan.~Progression (P): A > 25% increase in tumor area (two diameters) provided that the patient has not had his/her dose of steroids decreased since the last evaluation period. This will not need a confirmatory scan. A concomitant decrease in steroid dose will rule out a progression designation during the first 2 months after completion of XRT." (NCT01402063)
Timeframe: Q 3 months on study then Q3 months in f/u for yr 1, q 4 months yr 2, q 6 months for approximately 4 ys.

Interventionparticipants (Number)
Radiation Plus PPX(CT210331
Radiation + Temozolomide15

(Phase III) Overall Survival (OS)

Survival time is defined as time from randomization to date of death from any cause and is estimated by the Kaplan-Meier method. Patients last known to be alive are censored at the date of last contact. Per the protocol, the pilot arms were not included in the Phase III analyses. (NCT00004259)
Timeframe: From randomization to date of death. Patients are followed until death. Analysis occurs after 155 deaths have been reported, estimated at 5.5 years from the study opening.

Interventionyears (Median)
Radiation Therapy + Temozolomide (TMZ)3.9
RT + BCNU/CCNU3.8

(Phase III) Progression-free Survival by MGMT Status

Progression is defined as a radiographic increase in size of the lesion by > 25%, recurrence of the study lesion, or the development of new lesions, confirmed by imaging. Progression-free survival time is defined as time from randomization to date of progression or death from any cause and is estimated by the Kaplan-Meier method. Patients last known to be alive are censored at the date of last contact. Tumor tissue samples were analyzed for methylation status of methyl guanine methyl transferase (MGMT), classified as methylated vs. unmethylated. (NCT00004259)
Timeframe: From randomization to date of death. Patients are followed until death. Analysis occurs after 155 deaths have been reported, estimated at 5.5 years from the study opening.

Interventionyears (Median)
Methylated MGMT4.0
Unmthylated MGMT2.1

(Phase III) Survival Time by MGMT Status

Survival time is defined as time from randomization to date of death from any cause and is estimated by the Kaplan-Meier method. Patients last known to be alive are censored at the date of last contact. Tumor tissue samples were analyzed for methylation status of methyl guanine methyl transferase (MGMT), classified as methylated vs. unmethylated. (NCT00004259)
Timeframe: From randomization to date of death. Patients are followed until death. Analysis occurs after 155 deaths have been reported, estimated at 5.5 years from the study opening.

Interventionyears (Median)
Methylated MGMT7.2
Unmthylated MGMT3.1

(Phase III) Time to Tumor Progression (TTP)

Three-year rate is reported. Progression is defined as a radiographic increase in size of the lesion by > 25%, recurrence of the study lesion, or the development of new lesions, confirmed by imaging. Time to tumor progression was estimated using the cumulative incidence function (CIF) on tumor progression, with death as a competing risk. Per the protocol, the pilot arms were not included in the Phase III analyses. (NCT00004259)
Timeframe: From randomization to date of death. Patients are followed until death. Analysis occurs after 155 deaths have been reported, estimated at 5.5 years from the study opening.

Interventionmonths (Median)
Radiation Therapy + Temozolomide (TMZ)45.4
RT + BCNU/CCNU54.7

(Phase I) Number of Subjects With Dose Limiting Toxicities (DLT) on the Two Pilot Arms

Adverse events were graded using CTCAE v2.0. Grade refers to the severity of the adverse event (AE). The CTCAE v2.0 assigns Grades 1 through 5 with unique clinical descriptions of severity for each AE based on this general guideline: Grade 1 Mild AE, Grade 2 Moderate AE, Grade 3 Severe AE, Grade 4 Life-threatening or disabling AE, Grade 5 Death related to AE. Dose limiting toxicity (DLT) was defined as grade 3+ pulmonary toxicity, grade 4+ thrombocytopenia (< 25,000 for 5 days), neutropenia (< 500/microl for 7 days), or neutropenia of any duration with fever requiring hospital admission after one dose reduction of 50% in BCNU. A 20% rate of grade 3+ pulmonary toxicities or a 40% rate of grade 4+ thrombocytopenia and neutropenia was considered unacceptable for a treatment arm combining RT, TMZ, and BCNU. (NCT00004259)
Timeframe: From start of treatment to 3 months

,
InterventionParticipants (Count of Participants)
Subjects with Pulmonary DLTSubjects with Hematologic DLT
Pilot Arm #1: RT+TMZ+BCNU14
Pilot Arm #2: RT+TMZ+BCNU03

(Phase III) Number of Patients With Grade 3 or Higher Toxicity

Adverse events were graded using CTCAE v2.0. Grade refers to the severity of the AE. The CTCAE v2.0 assigns Grades 1 through 5 with unique clinical descriptions of severity for each AE based on this general guideline: Grade 1 Mild AE, Grade 2 Moderate AE, Grade 3 Severe AE, Grade 4 Life-threatening or disabling AE, Grade 5 Death related to AE. The number of patients with grade or higher toxicity was calculated overall and for non-hematologic toxicity only. Per the protocol, the pilot arms were not included in the Phase III analyses. (NCT00004259)
Timeframe: From randomization to date of death. Patients are followed until death. Analysis occurs after 155 deaths have been reported, estimated at 5.5 years from the study opening.

,
Interventionparticipants (Number)
Overall toxicityNon-hematologic toxicity
Radiation Therapy + Temozolomide (TMZ)4631
RT + BCNU/CCNU7534

Median Overall Survival (OS) in Phase II Participants - Prior Bevacizumab and Bevacizumab Naive

Two groups of patients in the Phase II trial will be considered separately, 1) participants who have not received previous bevacizumab and 2) participants who have received bevacizumab as part of first-line treatment. Overall survival is measured as the interval from first study treatment until date of death, or date last known alive. (NCT01349660)
Timeframe: every 12 weeks for up to 60 months

Interventionmonths (Median)
Phase II Participants - Prior Bevacizumab6.6
Phase II Participants - Bevacizumab Naive10.8

Median Progression-Free Survival (PFS) in Phase II Participants - Prior Bevacizumab and Bevacizumab Naive

Two groups of patients in the Phase II trial will be considered separately, 1) participants who have not received previous bevacizumab and 2) participants who have received bevacizumab as part of first-line treatment. PFS is measured from the date of first protocol treatment until date of disease progression or death occurs, or date of last adequate tumor assessment using RANO or McDonald criteria. McDonald disease progression criteria: a 25% or greater increase in sum of the diameters of lesions, new lesions, or clinical deterioration (McDonald et al, 1990). RANO disease progression criteria: a 25% or greater increase in the enhancing lesions sum compared with smallest tumor measurement, significant increase in T2/FLAIR nonenhancing lesion on stable or increasing corticosteroids, new lesions, or clinical deterioration (Wen et al 2010) (NCT01349660)
Timeframe: every 8 weeks for up to 33 months

Interventionmonths (Median)
Phase II Patients With Prior Bevacizumab Treatment.2.8
Phase II Patients Without Prior Bevacizumab Treatment5.3

Number of Phase I Patients Receiving 60mg or 80mg BKM120 Experiencing a Dose-Limiting Toxicity (DLT) to Determine the Optimal Dosage

The optimal dose of BKM120 to administer in combination with standard dose bevacizumab determined as the dose at which ≤1 of 6 patients experiences a DLT assessed using NCI CTCAE v4.03 during Cycle 1 (28 days). The optimal dose of BKM120 was determined to be 60 mg by mouth (PO), once a day for each 28 day cycle along with bevacizumab, administered 10 mg/kg intravenously (IV) on Day 1 and Day 15 of each 28 day cycle. (NCT01349660)
Timeframe: Collected from day of first dose to the end of the first treatment cycle, up to 28 days

InterventionParticipants (Count of Participants)
Phase I Dose Level 1 (60 mg BKM120, 10mg/kg Bevacizumab)0
Phase I Dose Level 2 (80 mg BKM120, 10mg/kg Bevacizumab)3

Overall Response (CR or PR) of Phase II Participants - Prior Bevacizumab and Bevacizumab Naive

Two groups of participants in the Phase II trial will be considered separately, 1) those who have not received previous bevacizumab and 2) those who have received bevacizumab as part of first-line treatment. Overall Response (OR) = number of patients with complete or partial responses (CR or PR) per McDonald or RANO criteria. McDonald: CR as disappearance of all disease for at least four weeks, no new lesions, no steroids; PR as 50% or greater decrease in the sum of all lesions compared with baseline for at least four weeks, no new lesions, stable or reduced steroids (McDonald 1990). RANO: CR as disappearance of all disease for at least 4 weeks, no new lesions, stable or improved nonenhancing lesions, and no steroid usage; and PR as a 50% or greater decrease in the sum of all lesions compared with baseline measurement for at least four weeks, no new lesions, stable or improved nonenhancing lesions on same or lower steroid dose compared to baseline (Wen 2010). (NCT01349660)
Timeframe: every 8 weeks, projected 24 months

InterventionParticipants (Count of Participants)
Phase II Participants - Prior Bevacizumab.1
Phase II Participants - Bevacizumab Naive18

Number of Participants With Grade 3/4/5 Serious Adverse Events and Adverse Events as a Measure of Safety and Tolerability

Defined as the number of participants with treatment-emergent grade 3/4/5 adverse events/serious adverse events utilizing the National Cancer Institute Common Technology Criteria for Adverse Events (NCI CTCAE) v4.03 (NCT01349660)
Timeframe: every 4 weeks for up to 5.2 years

,,
InterventionParticipants (Count of Participants)
FatigueConfusionHyperglycemiaDiarrheaAlanine aminotransferase increasedHypertensionSeizureAstheniaAspartate Aminotransferase IncreasedHypertriglyceridemiaAbdominal painAltered Mental StatusGait DisturbanceAtaxiaLipase IncreasedMuscle WeaknessPneumoniaSepsisRespiratory FailureThrombocytopeniaHypercholesterolemiaMucositisAnorexiaMemory ImpairmentPruritisVomitingMood AlterationWeight LossNeutropeniaDehydrationDyspneaHemorrhageSomnolenceTaste AlterationAgitationDysarthriaFallHypermagnesemiaEjection Fraction DecreasedElevated Liver EnzymesHypoalbuminemiaHypophosphatemiaPsychosisSuicidal IdeationThromboembolic EventAkathisiaCellulitisChronic Obstructive Pulmonary DiseaseDeliriumDiabetic KetoacidosisEnteritisFemale Genital Tract FistulaGastrointestinal InfectionHyperlipidemiaIntracranial HemorrhageLeft Ventricular Systolic DysfunctionNecrotizing FasciitisPalsyParalysisPersonality ChangeSyncopeTransaminitisUrine Output DecreasedVaginal FistulaVolume DepletionHeadacheHypokalemiaHyponatremiaNauseaProteinuriaRashUrinary Tract Infection
Phase I - Dose Level 1 (60 mg BKM, 10mg/kg Bevacizumab)101000010000110010100010000000001000000000000010100000000000000000000000
Phase I - Dose Level 2 (80 mg BKM120, 10mg/kg Bevacizumab)000110010011010000000100110001000100000001000000001000000000000011002012
Phase II - (60 mg BKM120, 10mg/kg Bevacizumab)885556645211102212111001001110110011111110111111010111111111111102431322

% of Participants Free of Disease Progression at 4mos Treated w/Zotiraciclib at the Maximum Tolerated Dose (MTD) in Combination With the Metronomic (mn) Temozolomide (TMZ) in Adult Patients With Recurrent Anaplastic Astrocytoma or Glioblastoma/Gliosarcoma

We first determined the MTDs in each ARM and we then performed the cohort expansion at the MTD in both ARMs separately, until we treated a total of 18 participants at this dose in each ARM. PFS is defined as the duration of time from start of registration to time of progression or death, whichever comes first. Progression was assessed by the Response Assessment in Neuro-Oncology Criteria (RANO). Progression is ≥25% increase in tumor volume compared to baseline in the sum of the products of perpendicular diameters of enhancing lesions compared with the smallest measurement obtained either at baseline or best response with the participant on stable or increasing doses of steroids. Significant increase in T2-weighted-Fluid-Attenuated Inversion Recovery (T2/FLAIR) non-enhancing lesions with the participant on stable or increasing doses of steroids (not caused by comorbid events). Any new lesions. (NCT02942264)
Timeframe: 4 months

Interventionpercentage of participants (Number)
All Participants25

% of Participants Free of Disease Progression at 4mos Treated w/Zotiraciclib at the Maximum Tolerated Dose in Combination Temozolomide w/Dose Dense Temozolomide Schedules in Adult Patients With Recurrent Anaplastic Astrocytoma or Glioblastoma/Gliosarcoma

We first determined the maximum tolerated dose (MTDs) in each ARM and we then performed the cohort expansion at the MTD in both ARMs separately, until we treated a total of 18 participants at this dose in each ARM. PFS is defined as the duration of time from start of registration to time of progression or death, whichever comes first. Progression was assessed by the Response Assessment in Neuro-Oncology Criteria (RANO). Progression is ≥25% increase in tumor volume compared to baseline in the sum of the products of perpendicular diameters of enhancing lesions compared with the smallest measurement obtained either at baseline or best response with the participant on stable or increasing doses of steroids. Significant increase in T2-weighted-Fluid-Attenuated Inversion Recovery (T2/FLAIR) non-enhancing lesions with the participant on stable or increasing doses of steroids (not caused by comorbid events). Any new lesions. (NCT02942264)
Timeframe: 4 months

Interventionpercentage of participants (Number)
All Participants40

Number of Participants With Serious and Non-serious Adverse Events Assessed by the Common Terminology Criteria for Adverse Events (CTCAE v4.0)

Here is the number of participants with serious and non-serious adverse events assessed by the Common Terminology Criteria for Adverse Events (CTCAE v4.0). A non-serious adverse event is any untoward medical occurrence. A serious adverse event is an adverse event or suspected adverse reaction that results in death, a life-threatening adverse drug experience, hospitalization, disruption of the ability to conduct normal life functions, congenital anomaly/birth defect or important medical events that jeopardize the patient or subject and may require medical or surgical intervention to prevent one of the previous outcomes mentioned. (NCT02942264)
Timeframe: Date treatment consent signed to date off study, approximately 15mo(m)/8days(d), 26m, 7m/26d, 13m/17d, 11m/30d, 12m/6d, 19m/11d, 9m/28d and 18m/21d for Group 1-9 respectively.

InterventionParticipants (Count of Participants)
ARM 1 Dose Level 0 - (Starting Dose)6
ARM 1 Dose Level 1 - (Dose Escalation)13
ARM 2 Dose Level 0 (Starting Dose)3
ARM 2 Dose 1 - (Dose Escalation)6
ARM 2 Dose 0 - (Dose De-escalation)3
ARM 2 Dose Level II - (Dose Escalation)2
ARM 2 Dose Level I - (Dose De-escalation)7
ARM 1 Dose Level 1 (MTD Level in ARM1)6
ARM 2 Dose Level 1 (MTD Level in ARM2)7

Phase I: Maximum Tolerated Dose (MTD) of Zotiraciclib (TG02) in Combination of Metronomic (mn) Temozolomide (TMZ) in Adult Patients With Recurrent Anaplastic Astrocytoma or Glioblastoma/Gliosarcoma

Maximum tolerated dose of metronomic (mn) Zotiraciclib (TG02) was assessed using the Bayesian Optimal Interval (BOIN) design. The MTD is defined as the dose for which the isotonic estimate of the toxicity rate is closest to the target toxicity rate of 0.35. If there are ties, we select the higher dose level when the isotonic estimate is lower than the target toxicity rate; and we select the lower dose level when the isotonic estimate is greater than the target toxicity rate of 0.35. (NCT02942264)
Timeframe: 4 weeks after initiation of treatment

Interventionmg/day (Number)
All Participants250

Phase I: Maximum Tolerated Dose (MTD) of Zotiraciclib in Combination With Dose Dense (dd) Temozolomide (TMZ) in Adult Patients With Recurrent Anaplastic Astrocytoma or Glioblastoma/Gliosarcoma

Maximum tolerated dose of Zotiraciclib (TG02) in combination with dose dense Temozolomide (TMZ) was assessed using the Bayesian Optimal Interval (BOIN) design. The MTD is defined as the dose for which the isotonic estimate of the toxicity rate is closest to the target toxicity rate of 0.35. If there are ties, we select the higher dose level when the isotonic estimate is lower than the target toxicity rate; and we select the lower dose level when the isotonic estimate is greater than the target toxicity rate of 0.35. (NCT02942264)
Timeframe: 4 weeks after initiation of treatment

Interventionmg/day (Number)
All Participants250

Phase I: Number of Participants With a Dose-limiting Toxicity (DLT)

DLT is defined as any adverse events attributed to the study drug. For example, Grade 4 neutropenia lasting 5 days or more. Febrile neutropenia defined as grade 3-4 neutropenia with fever ≥38.5ºC and/or infection requiring antibiotic or antifungal treatment. Nausea or vomiting that responds to symptomatic therapy and lasts ≤7 days. Fatigue that responds to symptomatic therapy and lasts ≤7 days. And weight gain (in patients on steroids). (NCT02942264)
Timeframe: 4 weeks after initiation of treatment

InterventionParticipants (Count of Participants)
ARM 1 Dose Level 0 - (Starting Dose)1
ARM 1 Dose Level 1 - (Dose Escalation)3
ARM 2 Dose Level 0 (Starting Dose)0
ARM 2 Dose 1 - (Dose Escalation)3
ARM 2 Dose 0 - (Dose De-escalation)1
ARM 2 Dose Level II - (Dose Escalation)1
ARM 2 Dose Level I - (Dose De-escalation)4

Circulating Chimeric Antigen Receptor (CAR+) Cells in Peripheral Blood at 1 Month Post Treatment

CAR and vector presence were quantitated in peripheral blood mononuclear cell (PBMC) samples using established polymerase chain reaction (PCR) techniques (NCT01454596)
Timeframe: 1 month post transplant

InterventionK/µL (Median)
Group A (Steroids) - Cohort 1: 1x10(7)23
Group A (Steroids) - Cohort 2: 3x10(7)70
Group A (Steroids) - Cohort 3: 1x10(8)36
Group B (No Steroids) - Cohort 1: 1x10(7)67
Group B (No Steroids) - Cohort 2: 3x10(7)7
Group B (No Steroids) - Cohort 3: 1x10(8)43
Group B (No Steroids) - Cohort 4: 3x10(8)28
Group B (No Steroids) - Cohort 5: 1x10(9)25
Combined Steroids/no Steroids) - Cohort 6: 3x10(9)12
Combined Steroids/no Steroids) - Cohort 7: 1x10(10)67.5
Combined Steroids/no Steroids) - Cohort 8: 3-6x10(10)NA
Combined Steroids/no Steroids) - Cohort 9: 3x10(10)8

Number of Participants With Serious and Non-serious Adverse Events Assessed by the Common Terminology Criteria in Adverse Events (CTCAE v4.0)

Here is the count of participants with serious and non-serious adverse events assessed by the Common Terminology Criteria in Adverse Events (CTCAE v4.0). A non-serious adverse event is any untoward medical occurrence. A serious adverse event is an adverse event or suspected adverse reaction that results in death, a life threatening adverse drug experience, hospitalization, disruption of the ability to conduct normal life functions, congenital anomaly/birth defect or important medical events that jeopardize the patient or subject and may require medical or surgical intervention to prevent one of the previous outcomes mentioned. (NCT01454596)
Timeframe: 51 dys Grp A, Cohort 1; Cohort 2:68 dys; Cohort 3:40 dys; Grp B, Cohort 1:67 dys; Cohort 2:48 dys; Cohort 3:55 dys; Cohort 4: 46 dys; Cohort 5:147 dys; C. Ster/No Ster Grp, Cohort 6:12 mos, 26 dys; Cohort 7:11 mos, 18 dys; Cohort 8:7 dys; Cohort 9:70 dys.

InterventionParticipants (Count of Participants)
Group A (Steroids) - Cohort 1: 1x10(7)1
Group A (Steroids) - Cohort 2: 3x10(7)1
Group A (Steroids) - Cohort 3: 1x10(8)1
Group B (No Steroids) - Cohort 1: 1x10(7)1
Group B (No Steroids) - Cohort 2: 3x10(7)1
Group B (No Steroids) - Cohort 3: 1x10(8)1
Group B (No Steroids) - Cohort 4: 3x10(8)1
Group B (No Steroids) - Cohort 5: 1x10(9)3
Combined Steroids/no Steroids) - Cohort 6: 3x10(9)3
Combined Steroids/no Steroids) - Cohort 7: 1x10(10)3
Combined Steroids/no Steroids) - Cohort 8: 3-6x10(10)1
Combined Steroids/no Steroids) - Cohort 9: 3x10(10)1

Number of Patients With an Objective Response

Objective response was assessed by comparison with baseline dynamic contrast enhanced magnetic resonance imaging with perfusion using Neuro-oncology Working Group proposed guidelines. Complete Response is disappearance of all measurable and non-measurable disease for at least 4 weeks. Partial Response is >/= 50% decrease in lesions for at least 4 weeks. Stable Disease does not meet the criteria for complete response, partial response or progression and requires stable lesions compared with baseline. Progression is >/= 25% increase in lesions. (NCT01454596)
Timeframe: 4 weeks after cell infusion and monthly as feasible up to 12 months

InterventionParticipants (Count of Participants)
Group A (Steroids) - Cohort 1: 1x10(7)0
Group A (Steroids) - Cohort 2: 3x10(7)0
Group A (Steroids) - Cohort 3: 1x10(8)0
Group B (No Steroids) - Cohort 1: 1x10(7)0
Group B (No Steroids) - Cohort 2: 3x10(7)0
Group B (No Steroids) - Cohort 3: 1x10(8)0
Group B (No Steroids) - Cohort 4: 3x10(8)0
Group B (No Steroids) - Cohort 5: 1x10(9)0
Combined Steroids/no Steroids) - Cohort 6: 3x10(9)0
Combined Steroids/no Steroids) - Cohort 7: 1x10(10)0
Combined Steroids/no Steroids) - Cohort 8: 3-6x10(10)0
Combined Steroids/no Steroids) - Cohort 9: 3x10(10)0

Number of Treatment Related Adverse Events

Aggregate of all adverse events ≥Grade 3 that are possibly, probably, and definitely related to treatment. Adverse events were assessed by the Common Terminology Criteria in Adverse Events (CTCAE v4.0). Per CTCAE, Grade 3 adverse events are severe, Grade 4 is life threatening, and Grade 5 is death. (NCT01454596)
Timeframe: From 4 weeks after cell infusion up to 77 days

Interventionadverse events (Number)
Group A (Steroids) - Cohort 1: 1x10(7)0
Group A (Steroids) - Cohort 2: 3x10(7)0
Group A (Steroids) - Cohort 3: 1x10(8)0
Group B (No Steroids) - Cohort 1: 1x10(7)0
Group B (No Steroids) - Cohort 2: 3x10(7)0
Group B (No Steroids) - Cohort 3: 1x10(8)0
Group B (No Steroids) - Cohort 4: 3x10(8)0
Group B (No Steroids) - Cohort 5: 1x10(9)0
Combined Steroids/no Steroids) - Cohort 6: 3x10(9)0
Combined Steroids/no Steroids) - Cohort 7: 1x10(10)0
Combined Steroids/no Steroids) - Cohort 8: 3-6x10(10)1
Combined Steroids/no Steroids) - Cohort 9: 3x10(10)1

Progression Free Survival

Progression was assessed by the Response Assessment in Neuro-Oncology (RANO) criteria and is defined as the circumstance when the magnetic resonance imaging (MRI) scan is ranked -2 (definitely worse) or -3 (development of a new lesion). (NCT01454596)
Timeframe: Time from the date of registration to the date of first observation of progressive disease up to 6 months after end of treatment

Interventionmonths (Median)
Group A (Steroids) - Cohort 1: 1x10(7)1.1
Group A (Steroids) - Cohort 2: 3x10(7)1.1
Group A (Steroids) - Cohort 3: 1x10(8)1.3
Group B (No Steroids) - Cohort 1: 1x10(7)1.9
Group B (No Steroids) - Cohort 2: 3x10(7)2.0
Group B (No Steroids) - Cohort 3: 1x10(8)1.5
Group B (No Steroids) - Cohort 4: 3x10(8)1.2
Group B (No Steroids) - Cohort 5: 1x10(9)1.1
Combined Steroids/no Steroids) - Cohort 6: 3x10(9)2.7
Combined Steroids/no Steroids) - Cohort 7: 1x10(10)1.1
Combined Steroids/no Steroids) - Cohort 8: 3-6x10(10)0
Combined Steroids/no Steroids) - Cohort 9: 3x10(10)2.0

Dose Limiting Toxicities (DLTs)

Number of Participants in Phase 1 with Dose Limiting Toxicities (DLTs) (NCT01465347)
Timeframe: During phase 1

InterventionParticipants (Count of Participants)
TSC 0.25 mg/kg - 9 Dose Group0

Number of Participants With Reduction in Tumor Size, According to Percentage of Tumor Reduction

The sum of the product of the diameters of the tumor (using recorded tumor diameter measurements made from brain MRI images) was used to express tumor size. Results were summarized for actual and percentage change from baseline. Individual subjects results were listed, including tumor volume and tumor response from independent reviewers. Investigator data were listed but not used in the analysis. Percent response (according to independent reviewer assessments) by percentage tumor reduction from tumor resection or definitive biopsy to the last MRI were summarized. (NCT01465347)
Timeframe: From Baseline to Week 110

,
InterventionParticipants (Count of Participants)
tumor not reduced0 to 39% tumor reduction40 to 63% tumor reduction64 to 93% tumor reduction94 to 99% tumor reduction100% tumor reduction
TSC 0.25 mg/kg - 18 Dose Group - Phase 210626211
TSC 0.25mg/kg - 9 Dose Group - Phase 1100002

Overall Survival

Participants in phase 2 (18 dose group, 6 weeks treatment with TSC) were monitored for up to 3 years (last follow-up - February 16, 2016). Overall Survival (OS) was defined as the length of time from the date of tumor resection surgery or definitive biopsy to the date of death. The OS analyses were performed using the Kaplan-Meier estimate method. The OS rates at 6, 12, 18 and 24 months were estimated. Median OS values were calculated; a corresponding 95% confidence interval for each median value was determined using a log rank analysis. The length of OS (in months) was calculated as follows: date of death or censored - date of surgery or definitive biopsy / 30.4375. (NCT01465347)
Timeframe: 6, 12, 18, 24 months

Interventionparticipants (Number)
6 month OS12 month OS18 month OS24 month OS
TSC 0.25 mg/kg - 18 Dose Group - Phase 289.371.243.836.3

Progression-Free Survival (PFS)

The PFS analyses were performed using the Kaplan-Meier estimate method. The PFS rates at 6, 12, 18 and 24 months were estimated. Median PFS values were calculated; a corresponding 95% confidence interval for each median value was determined using a log rank analysis. Time to disease progression (in months) was calculated as follows: date of event* or censoring - date of surgery or definitive biopsy / 30.4375; *event = first tumor progression or death. (NCT01465347)
Timeframe: 6,12,18, 24 months

Interventionpercentage of participants (Number)
6 months12 months18 months24 months
TSC 0.25 mg/kg - 18 Dose Group - Phase 230.99.94.00.0

Radiographic Response Assessed by Macdonald Criteria Every 2 Months

All patients will have their tumor measurements recorded at baseline and at the time of each MRI scan. Lesions must be measured in two dimensions. (NCT00026494)
Timeframe: 2 years

,,,
Interventionparticipants (Number)
Stable Disease (SD)Progression of Disease (POD)Partial Response (PR)Minor Response (MR)Complete Response (CR)
15mg/m2 - Vinorelbine32000
20mg/m2 - Vinorelbine21100
25mg/m2 - Vinorelbine411010
30mg/m2 - Vinorelbine312001

Overall Survival

(NCT00582075)
Timeframe: 2 years

Interventionweeks (Median)
Radiosurgery 15-24 Gy + Adjuvant Temozolomide31

Percentage of Participants With Distant Brain Failure (DBF) at One Year

Patients developing distant brain failure (DBF) at one year. An approximation method was used to arrive at the reported percentage. (NCT00582075)
Timeframe: 1 years

Interventionpercentage of participants (Number)
Radiosurgery 15-24 Gy + Adjuvant Temozolomide37

Reviews

372 reviews available for temozolomide and Brain Neoplasms

ArticleYear
Improving temozolomide biopharmaceutical properties in glioblastoma multiforme (GBM) treatment using GBM-targeting nanocarriers.
    European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 2021, Volume: 168

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Drug Carriers; Drug Delivery Systems; D

2021
Improving temozolomide biopharmaceutical properties in glioblastoma multiforme (GBM) treatment using GBM-targeting nanocarriers.
    European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 2021, Volume: 168

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Drug Carriers; Drug Delivery Systems; D

2021
Improving temozolomide biopharmaceutical properties in glioblastoma multiforme (GBM) treatment using GBM-targeting nanocarriers.
    European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 2021, Volume: 168

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Drug Carriers; Drug Delivery Systems; D

2021
MGMT promoter methylation testing to predict overall survival in people with glioblastoma treated with temozolomide: a comprehensive meta-analysis based on a Cochrane Systematic Review.
    Neuro-oncology, 2021, 09-01, Volume: 23, Issue:9

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; DNA Methylation; DNA Modification Methylases; DN

2021
MGMT promoter methylation testing to predict overall survival in people with glioblastoma treated with temozolomide: a comprehensive meta-analysis based on a Cochrane Systematic Review.
    Neuro-oncology, 2021, 09-01, Volume: 23, Issue:9

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; DNA Methylation; DNA Modification Methylases; DN

2021
MGMT promoter methylation testing to predict overall survival in people with glioblastoma treated with temozolomide: a comprehensive meta-analysis based on a Cochrane Systematic Review.
    Neuro-oncology, 2021, 09-01, Volume: 23, Issue:9

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; DNA Methylation; DNA Modification Methylases; DN

2021
Temozolomide is a risk factor for invasive pulmonary aspergillosis: A case report and literature review.
    Infectious diseases now, 2021, Volume: 51, Issue:7

    Topics: Aged; Brain Neoplasms; Glioblastoma; Humans; Invasive Pulmonary Aspergillosis; Male; Risk Factors; T

2021
Temozolomide is a risk factor for invasive pulmonary aspergillosis: A case report and literature review.
    Infectious diseases now, 2021, Volume: 51, Issue:7

    Topics: Aged; Brain Neoplasms; Glioblastoma; Humans; Invasive Pulmonary Aspergillosis; Male; Risk Factors; T

2021
Temozolomide is a risk factor for invasive pulmonary aspergillosis: A case report and literature review.
    Infectious diseases now, 2021, Volume: 51, Issue:7

    Topics: Aged; Brain Neoplasms; Glioblastoma; Humans; Invasive Pulmonary Aspergillosis; Male; Risk Factors; T

2021
Comprehensive pharmacogenomics characterization of temozolomide response in gliomas.
    European journal of pharmacology, 2021, Dec-05, Volume: 912

    Topics: Brain Neoplasms; DNA Repair; Glioma; Humans; Pharmacogenetics; Polymorphism, Genetic; Temozolomide

2021
Comprehensive pharmacogenomics characterization of temozolomide response in gliomas.
    European journal of pharmacology, 2021, Dec-05, Volume: 912

    Topics: Brain Neoplasms; DNA Repair; Glioma; Humans; Pharmacogenetics; Polymorphism, Genetic; Temozolomide

2021
Comprehensive pharmacogenomics characterization of temozolomide response in gliomas.
    European journal of pharmacology, 2021, Dec-05, Volume: 912

    Topics: Brain Neoplasms; DNA Repair; Glioma; Humans; Pharmacogenetics; Polymorphism, Genetic; Temozolomide

2021
Response and safety of whole-brain radiotherapy plus temozolomide for patients with brain metastases of non-small-cell lung cancer: A meta-analysis.
    Thoracic cancer, 2021, Volume: 12, Issue:23

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Carcinoma, Non-Small-Cell Lung; Combined Modalit

2021
Response and safety of whole-brain radiotherapy plus temozolomide for patients with brain metastases of non-small-cell lung cancer: A meta-analysis.
    Thoracic cancer, 2021, Volume: 12, Issue:23

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Carcinoma, Non-Small-Cell Lung; Combined Modalit

2021
Response and safety of whole-brain radiotherapy plus temozolomide for patients with brain metastases of non-small-cell lung cancer: A meta-analysis.
    Thoracic cancer, 2021, Volume: 12, Issue:23

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Carcinoma, Non-Small-Cell Lung; Combined Modalit

2021
Temozolomide sensitivity of malignant glioma cell lines - a systematic review assessing consistencies between in vitro studies.
    BMC cancer, 2021, Nov-18, Volume: 21, Issue:1

    Topics: Animals; Antineoplastic Agents, Alkylating; Bias; Brain Neoplasms; Cell Line, Tumor; Cell Survival;

2021
Temozolomide sensitivity of malignant glioma cell lines - a systematic review assessing consistencies between in vitro studies.
    BMC cancer, 2021, Nov-18, Volume: 21, Issue:1

    Topics: Animals; Antineoplastic Agents, Alkylating; Bias; Brain Neoplasms; Cell Line, Tumor; Cell Survival;

2021
Temozolomide sensitivity of malignant glioma cell lines - a systematic review assessing consistencies between in vitro studies.
    BMC cancer, 2021, Nov-18, Volume: 21, Issue:1

    Topics: Animals; Antineoplastic Agents, Alkylating; Bias; Brain Neoplasms; Cell Line, Tumor; Cell Survival;

2021
The current landscape of systemic therapy for recurrent glioblastoma: A systematic review of randomized-controlled trials.
    Critical reviews in oncology/hematology, 2022, Volume: 169

    Topics: Adult; Bevacizumab; Brain Neoplasms; Glioblastoma; Humans; Neoplasm Recurrence, Local; Progression-F

2022
The current landscape of systemic therapy for recurrent glioblastoma: A systematic review of randomized-controlled trials.
    Critical reviews in oncology/hematology, 2022, Volume: 169

    Topics: Adult; Bevacizumab; Brain Neoplasms; Glioblastoma; Humans; Neoplasm Recurrence, Local; Progression-F

2022
The current landscape of systemic therapy for recurrent glioblastoma: A systematic review of randomized-controlled trials.
    Critical reviews in oncology/hematology, 2022, Volume: 169

    Topics: Adult; Bevacizumab; Brain Neoplasms; Glioblastoma; Humans; Neoplasm Recurrence, Local; Progression-F

2022
Newly Diagnosed Glioblastoma in Elderly Patients.
    Current oncology reports, 2022, Volume: 24, Issue:3

    Topics: Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; DNA Methylation; Glioblastoma; Humans; Pre

2022
Newly Diagnosed Glioblastoma in Elderly Patients.
    Current oncology reports, 2022, Volume: 24, Issue:3

    Topics: Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; DNA Methylation; Glioblastoma; Humans; Pre

2022
Newly Diagnosed Glioblastoma in Elderly Patients.
    Current oncology reports, 2022, Volume: 24, Issue:3

    Topics: Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; DNA Methylation; Glioblastoma; Humans; Pre

2022
Oxamate targeting aggressive cancers with special emphasis to brain tumors.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2022, Volume: 147

    Topics: Animals; Brain Neoplasms; Cell Line, Tumor; Glycolysis; Humans; L-Lactate Dehydrogenase; Mitochondri

2022
Oxamate targeting aggressive cancers with special emphasis to brain tumors.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2022, Volume: 147

    Topics: Animals; Brain Neoplasms; Cell Line, Tumor; Glycolysis; Humans; L-Lactate Dehydrogenase; Mitochondri

2022
Oxamate targeting aggressive cancers with special emphasis to brain tumors.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2022, Volume: 147

    Topics: Animals; Brain Neoplasms; Cell Line, Tumor; Glycolysis; Humans; L-Lactate Dehydrogenase; Mitochondri

2022
Combining apatinib and temozolomide for brainstem glioblastoma: a case report and review of literature.
    Annals of palliative medicine, 2022, Volume: 11, Issue:1

    Topics: Adult; Brain Neoplasms; Brain Stem; Dacarbazine; Glioblastoma; Humans; Male; Pyridines; Temozolomide

2022
Combining apatinib and temozolomide for brainstem glioblastoma: a case report and review of literature.
    Annals of palliative medicine, 2022, Volume: 11, Issue:1

    Topics: Adult; Brain Neoplasms; Brain Stem; Dacarbazine; Glioblastoma; Humans; Male; Pyridines; Temozolomide

2022
Combining apatinib and temozolomide for brainstem glioblastoma: a case report and review of literature.
    Annals of palliative medicine, 2022, Volume: 11, Issue:1

    Topics: Adult; Brain Neoplasms; Brain Stem; Dacarbazine; Glioblastoma; Humans; Male; Pyridines; Temozolomide

2022
Recent Development in NKT-Based Immunotherapy of Glioblastoma: From Bench to Bedside.
    International journal of molecular sciences, 2022, Jan-24, Volume: 23, Issue:3

    Topics: Blood-Brain Barrier; Brain Neoplasms; Glioblastoma; Humans; Immunologic Factors; Immunotherapy; Lymp

2022
Recent Development in NKT-Based Immunotherapy of Glioblastoma: From Bench to Bedside.
    International journal of molecular sciences, 2022, Jan-24, Volume: 23, Issue:3

    Topics: Blood-Brain Barrier; Brain Neoplasms; Glioblastoma; Humans; Immunologic Factors; Immunotherapy; Lymp

2022
Recent Development in NKT-Based Immunotherapy of Glioblastoma: From Bench to Bedside.
    International journal of molecular sciences, 2022, Jan-24, Volume: 23, Issue:3

    Topics: Blood-Brain Barrier; Brain Neoplasms; Glioblastoma; Humans; Immunologic Factors; Immunotherapy; Lymp

2022
Congress of Neurological Surgeons systematic review and evidence-based guidelines update on the role of cytotoxic chemotherapy and other cytotoxic therapies in the management of progressive glioblastoma in adults.
    Journal of neuro-oncology, 2022, Volume: 158, Issue:2

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Glioblastoma; Humans;

2022
Congress of Neurological Surgeons systematic review and evidence-based guidelines update on the role of cytotoxic chemotherapy and other cytotoxic therapies in the management of progressive glioblastoma in adults.
    Journal of neuro-oncology, 2022, Volume: 158, Issue:2

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Glioblastoma; Humans;

2022
Congress of Neurological Surgeons systematic review and evidence-based guidelines update on the role of cytotoxic chemotherapy and other cytotoxic therapies in the management of progressive glioblastoma in adults.
    Journal of neuro-oncology, 2022, Volume: 158, Issue:2

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Glioblastoma; Humans;

2022
Accelerated hypofractionated radiation for elderly or frail patients with a newly diagnosed glioblastoma: A pooled analysis of patient-level data from 4 prospective trials.
    Cancer, 2022, 06-15, Volume: 128, Issue:12

    Topics: Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Frail Elderly; Glioblastoma; Humans; Obser

2022
Accelerated hypofractionated radiation for elderly or frail patients with a newly diagnosed glioblastoma: A pooled analysis of patient-level data from 4 prospective trials.
    Cancer, 2022, 06-15, Volume: 128, Issue:12

    Topics: Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Frail Elderly; Glioblastoma; Humans; Obser

2022
Accelerated hypofractionated radiation for elderly or frail patients with a newly diagnosed glioblastoma: A pooled analysis of patient-level data from 4 prospective trials.
    Cancer, 2022, 06-15, Volume: 128, Issue:12

    Topics: Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Frail Elderly; Glioblastoma; Humans; Obser

2022
Natural Compounds as Promising Adjuvant Agents in The Treatment of Gliomas.
    International journal of molecular sciences, 2022, Mar-20, Volume: 23, Issue:6

    Topics: Blood-Brain Barrier; Brain; Brain Neoplasms; Cell Line, Tumor; Glioblastoma; Humans; Temozolomide

2022
Natural Compounds as Promising Adjuvant Agents in The Treatment of Gliomas.
    International journal of molecular sciences, 2022, Mar-20, Volume: 23, Issue:6

    Topics: Blood-Brain Barrier; Brain; Brain Neoplasms; Cell Line, Tumor; Glioblastoma; Humans; Temozolomide

2022
Natural Compounds as Promising Adjuvant Agents in The Treatment of Gliomas.
    International journal of molecular sciences, 2022, Mar-20, Volume: 23, Issue:6

    Topics: Blood-Brain Barrier; Brain; Brain Neoplasms; Cell Line, Tumor; Glioblastoma; Humans; Temozolomide

2022
Executive summary of American Radium Society's appropriate use criteria for the postoperative management of lower grade gliomas.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2022, Volume: 170

    Topics: Astrocytoma; Brain Neoplasms; Glioma; Humans; Oligodendroglioma; Radium; Temozolomide

2022
Executive summary of American Radium Society's appropriate use criteria for the postoperative management of lower grade gliomas.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2022, Volume: 170

    Topics: Astrocytoma; Brain Neoplasms; Glioma; Humans; Oligodendroglioma; Radium; Temozolomide

2022
Executive summary of American Radium Society's appropriate use criteria for the postoperative management of lower grade gliomas.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2022, Volume: 170

    Topics: Astrocytoma; Brain Neoplasms; Glioma; Humans; Oligodendroglioma; Radium; Temozolomide

2022
Temozolomide Resistance: A Multifarious Review on Mechanisms Beyond
    CNS & neurological disorders drug targets, 2023, Volume: 22, Issue:6

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Dacarbazine; DNA; Glioblastoma

2023
Temozolomide Resistance: A Multifarious Review on Mechanisms Beyond
    CNS & neurological disorders drug targets, 2023, Volume: 22, Issue:6

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Dacarbazine; DNA; Glioblastoma

2023
Temozolomide Resistance: A Multifarious Review on Mechanisms Beyond
    CNS & neurological disorders drug targets, 2023, Volume: 22, Issue:6

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Dacarbazine; DNA; Glioblastoma

2023
Recent Advances in the Therapeutic Strategies of Glioblastoma Multiforme.
    Neuroscience, 2022, 05-21, Volume: 491

    Topics: Brain Neoplasms; Glioblastoma; Humans; Immunotherapy; Neoplastic Stem Cells; Temozolomide

2022
Recent Advances in the Therapeutic Strategies of Glioblastoma Multiforme.
    Neuroscience, 2022, 05-21, Volume: 491

    Topics: Brain Neoplasms; Glioblastoma; Humans; Immunotherapy; Neoplastic Stem Cells; Temozolomide

2022
Recent Advances in the Therapeutic Strategies of Glioblastoma Multiforme.
    Neuroscience, 2022, 05-21, Volume: 491

    Topics: Brain Neoplasms; Glioblastoma; Humans; Immunotherapy; Neoplastic Stem Cells; Temozolomide

2022
Optimal managements of elderly patients with glioblastoma.
    Japanese journal of clinical oncology, 2022, 08-05, Volume: 52, Issue:8

    Topics: Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Glioblastoma; Humans; Quality of Life; Tem

2022
Optimal managements of elderly patients with glioblastoma.
    Japanese journal of clinical oncology, 2022, 08-05, Volume: 52, Issue:8

    Topics: Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Glioblastoma; Humans; Quality of Life; Tem

2022
Optimal managements of elderly patients with glioblastoma.
    Japanese journal of clinical oncology, 2022, 08-05, Volume: 52, Issue:8

    Topics: Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Glioblastoma; Humans; Quality of Life; Tem

2022
Radiotherapy-drug combinations in the treatment of glioblastoma: a brief review.
    CNS oncology, 2022, 06-01, Volume: 11, Issue:2

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Drug Combinations; Gl

2022
Radiotherapy-drug combinations in the treatment of glioblastoma: a brief review.
    CNS oncology, 2022, 06-01, Volume: 11, Issue:2

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Drug Combinations; Gl

2022
Radiotherapy-drug combinations in the treatment of glioblastoma: a brief review.
    CNS oncology, 2022, 06-01, Volume: 11, Issue:2

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Drug Combinations; Gl

2022
Novel therapeutics and drug-delivery approaches in the modulation of glioblastoma stem cell resistance.
    Therapeutic delivery, 2022, Volume: 13, Issue:4

    Topics: Brain Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; Drug Therapy, Combination; Glioblastom

2022
Novel therapeutics and drug-delivery approaches in the modulation of glioblastoma stem cell resistance.
    Therapeutic delivery, 2022, Volume: 13, Issue:4

    Topics: Brain Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; Drug Therapy, Combination; Glioblastom

2022
Novel therapeutics and drug-delivery approaches in the modulation of glioblastoma stem cell resistance.
    Therapeutic delivery, 2022, Volume: 13, Issue:4

    Topics: Brain Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; Drug Therapy, Combination; Glioblastom

2022
Newly Diagnosed Multifocal GBM: A Monocentric Experience and Literature Review.
    Current oncology (Toronto, Ont.), 2022, 05-11, Volume: 29, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Humans; Middle Aged; Retrospective

2022
Newly Diagnosed Multifocal GBM: A Monocentric Experience and Literature Review.
    Current oncology (Toronto, Ont.), 2022, 05-11, Volume: 29, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Humans; Middle Aged; Retrospective

2022
Newly Diagnosed Multifocal GBM: A Monocentric Experience and Literature Review.
    Current oncology (Toronto, Ont.), 2022, 05-11, Volume: 29, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Humans; Middle Aged; Retrospective

2022
Temozolomide: An Overview of Biological Properties, Drug Delivery Nanosystems, and Analytical Methods.
    Current pharmaceutical design, 2022, Volume: 28, Issue:25

    Topics: Brain Neoplasms; Cell Line, Tumor; Glioblastoma; Guanine; Humans; Temozolomide

2022
Temozolomide: An Overview of Biological Properties, Drug Delivery Nanosystems, and Analytical Methods.
    Current pharmaceutical design, 2022, Volume: 28, Issue:25

    Topics: Brain Neoplasms; Cell Line, Tumor; Glioblastoma; Guanine; Humans; Temozolomide

2022
Temozolomide: An Overview of Biological Properties, Drug Delivery Nanosystems, and Analytical Methods.
    Current pharmaceutical design, 2022, Volume: 28, Issue:25

    Topics: Brain Neoplasms; Cell Line, Tumor; Glioblastoma; Guanine; Humans; Temozolomide

2022
Temozolomide Efficacy and Metabolism: The Implicit Relevance of Nanoscale Delivery Systems.
    Molecules (Basel, Switzerland), 2022, May-30, Volume: 27, Issue:11

    Topics: Adult; Antibodies, Monoclonal; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor;

2022
Temozolomide Efficacy and Metabolism: The Implicit Relevance of Nanoscale Delivery Systems.
    Molecules (Basel, Switzerland), 2022, May-30, Volume: 27, Issue:11

    Topics: Adult; Antibodies, Monoclonal; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor;

2022
Temozolomide Efficacy and Metabolism: The Implicit Relevance of Nanoscale Delivery Systems.
    Molecules (Basel, Switzerland), 2022, May-30, Volume: 27, Issue:11

    Topics: Adult; Antibodies, Monoclonal; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor;

2022
Management of newly diagnosed glioblastoma multiforme: current state of the art and emerging therapeutic approaches.
    Medical oncology (Northwood, London, England), 2022, Jun-18, Volume: 39, Issue:9

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Glioblastoma; Humans; Immunotherapy; Temozolomid

2022
Management of newly diagnosed glioblastoma multiforme: current state of the art and emerging therapeutic approaches.
    Medical oncology (Northwood, London, England), 2022, Jun-18, Volume: 39, Issue:9

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Glioblastoma; Humans; Immunotherapy; Temozolomid

2022
Management of newly diagnosed glioblastoma multiforme: current state of the art and emerging therapeutic approaches.
    Medical oncology (Northwood, London, England), 2022, Jun-18, Volume: 39, Issue:9

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Glioblastoma; Humans; Immunotherapy; Temozolomid

2022
Comparative efficacy and safety of therapeutics for elderly glioblastoma patients: A Bayesian network analysis.
    Pharmacological research, 2022, Volume: 182

    Topics: Aged; Antineoplastic Agents, Alkylating; Bayes Theorem; Brain Neoplasms; Dacarbazine; Glioblastoma;

2022
Comparative efficacy and safety of therapeutics for elderly glioblastoma patients: A Bayesian network analysis.
    Pharmacological research, 2022, Volume: 182

    Topics: Aged; Antineoplastic Agents, Alkylating; Bayes Theorem; Brain Neoplasms; Dacarbazine; Glioblastoma;

2022
Comparative efficacy and safety of therapeutics for elderly glioblastoma patients: A Bayesian network analysis.
    Pharmacological research, 2022, Volume: 182

    Topics: Aged; Antineoplastic Agents, Alkylating; Bayes Theorem; Brain Neoplasms; Dacarbazine; Glioblastoma;

2022
Nanomedicine for glioblastoma: Progress and future prospects.
    Seminars in cancer biology, 2022, Volume: 86, Issue:Pt 2

    Topics: Blood-Brain Barrier; Brain Neoplasms; Glioblastoma; Humans; Nanomedicine; Temozolomide

2022
Nanomedicine for glioblastoma: Progress and future prospects.
    Seminars in cancer biology, 2022, Volume: 86, Issue:Pt 2

    Topics: Blood-Brain Barrier; Brain Neoplasms; Glioblastoma; Humans; Nanomedicine; Temozolomide

2022
Nanomedicine for glioblastoma: Progress and future prospects.
    Seminars in cancer biology, 2022, Volume: 86, Issue:Pt 2

    Topics: Blood-Brain Barrier; Brain Neoplasms; Glioblastoma; Humans; Nanomedicine; Temozolomide

2022
Updates in the Management of Recurrent Glioblastoma Multiforme.
    Journal of neurological surgery. Part A, Central European neurosurgery, 2023, Volume: 84, Issue:2

    Topics: Bevacizumab; Brain Neoplasms; Glioblastoma; Humans; Neoplasm Recurrence, Local; Temozolomide

2023
Updates in the Management of Recurrent Glioblastoma Multiforme.
    Journal of neurological surgery. Part A, Central European neurosurgery, 2023, Volume: 84, Issue:2

    Topics: Bevacizumab; Brain Neoplasms; Glioblastoma; Humans; Neoplasm Recurrence, Local; Temozolomide

2023
Updates in the Management of Recurrent Glioblastoma Multiforme.
    Journal of neurological surgery. Part A, Central European neurosurgery, 2023, Volume: 84, Issue:2

    Topics: Bevacizumab; Brain Neoplasms; Glioblastoma; Humans; Neoplasm Recurrence, Local; Temozolomide

2023
Glioblastoma and Methionine Addiction.
    International journal of molecular sciences, 2022, Jun-28, Volume: 23, Issue:13

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Epigenesis, Genetic; Glioblastoma; Humans; Methi

2022
Glioblastoma and Methionine Addiction.
    International journal of molecular sciences, 2022, Jun-28, Volume: 23, Issue:13

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Epigenesis, Genetic; Glioblastoma; Humans; Methi

2022
Glioblastoma and Methionine Addiction.
    International journal of molecular sciences, 2022, Jun-28, Volume: 23, Issue:13

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Epigenesis, Genetic; Glioblastoma; Humans; Methi

2022
Glioblastoma Treatment: State-of-the-Art and Future Perspectives.
    International journal of molecular sciences, 2022, Jun-29, Volume: 23, Issue:13

    Topics: Bevacizumab; Brain Neoplasms; Dacarbazine; Glioblastoma; Humans; Temozolomide

2022
Glioblastoma Treatment: State-of-the-Art and Future Perspectives.
    International journal of molecular sciences, 2022, Jun-29, Volume: 23, Issue:13

    Topics: Bevacizumab; Brain Neoplasms; Dacarbazine; Glioblastoma; Humans; Temozolomide

2022
Glioblastoma Treatment: State-of-the-Art and Future Perspectives.
    International journal of molecular sciences, 2022, Jun-29, Volume: 23, Issue:13

    Topics: Bevacizumab; Brain Neoplasms; Dacarbazine; Glioblastoma; Humans; Temozolomide

2022
Intracranial dissemination of glioblastoma multiforme: a case report and literature review.
    The Journal of international medical research, 2022, Volume: 50, Issue:7

    Topics: Adult; Brain Neoplasms; Chemoradiotherapy; Chemotherapy, Adjuvant; Female; Glioblastoma; Humans; Tem

2022
Intracranial dissemination of glioblastoma multiforme: a case report and literature review.
    The Journal of international medical research, 2022, Volume: 50, Issue:7

    Topics: Adult; Brain Neoplasms; Chemoradiotherapy; Chemotherapy, Adjuvant; Female; Glioblastoma; Humans; Tem

2022
Intracranial dissemination of glioblastoma multiforme: a case report and literature review.
    The Journal of international medical research, 2022, Volume: 50, Issue:7

    Topics: Adult; Brain Neoplasms; Chemoradiotherapy; Chemotherapy, Adjuvant; Female; Glioblastoma; Humans; Tem

2022
MicroRNA delivery systems in glioma therapy and perspectives: A systematic review.
    Journal of controlled release : official journal of the Controlled Release Society, 2022, Volume: 349

    Topics: Arginine; Brain Neoplasms; Glioma; Humans; Liposomes; MicroRNAs; Nanoparticles; Peptides; Temozolomi

2022
MicroRNA delivery systems in glioma therapy and perspectives: A systematic review.
    Journal of controlled release : official journal of the Controlled Release Society, 2022, Volume: 349

    Topics: Arginine; Brain Neoplasms; Glioma; Humans; Liposomes; MicroRNAs; Nanoparticles; Peptides; Temozolomi

2022
MicroRNA delivery systems in glioma therapy and perspectives: A systematic review.
    Journal of controlled release : official journal of the Controlled Release Society, 2022, Volume: 349

    Topics: Arginine; Brain Neoplasms; Glioma; Humans; Liposomes; MicroRNAs; Nanoparticles; Peptides; Temozolomi

2022
Current Considerations in the Treatment of Grade 3 Gliomas.
    Current treatment options in oncology, 2022, Volume: 23, Issue:9

    Topics: Astrocytoma; Brain Neoplasms; Glioma; Humans; Isocitrate Dehydrogenase; Lymphoma, Follicular; Mutati

2022
Current Considerations in the Treatment of Grade 3 Gliomas.
    Current treatment options in oncology, 2022, Volume: 23, Issue:9

    Topics: Astrocytoma; Brain Neoplasms; Glioma; Humans; Isocitrate Dehydrogenase; Lymphoma, Follicular; Mutati

2022
Current Considerations in the Treatment of Grade 3 Gliomas.
    Current treatment options in oncology, 2022, Volume: 23, Issue:9

    Topics: Astrocytoma; Brain Neoplasms; Glioma; Humans; Isocitrate Dehydrogenase; Lymphoma, Follicular; Mutati

2022
Immune-checkpoint inhibitors for glioblastoma: what have we learned?
    Arquivos de neuro-psiquiatria, 2022, Volume: 80, Issue:5 Suppl 1

    Topics: Brain Neoplasms; Clinical Trials, Phase III as Topic; Glioblastoma; Humans; Immune Checkpoint Inhibi

2022
Immune-checkpoint inhibitors for glioblastoma: what have we learned?
    Arquivos de neuro-psiquiatria, 2022, Volume: 80, Issue:5 Suppl 1

    Topics: Brain Neoplasms; Clinical Trials, Phase III as Topic; Glioblastoma; Humans; Immune Checkpoint Inhibi

2022
Immune-checkpoint inhibitors for glioblastoma: what have we learned?
    Arquivos de neuro-psiquiatria, 2022, Volume: 80, Issue:5 Suppl 1

    Topics: Brain Neoplasms; Clinical Trials, Phase III as Topic; Glioblastoma; Humans; Immune Checkpoint Inhibi

2022
Polymeric and small molecule-conjugates of temozolomide as improved therapeutic agents for glioblastoma multiforme.
    Journal of controlled release : official journal of the Controlled Release Society, 2022, Volume: 350

    Topics: Alkylating Agents; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Delayed-Act

2022
Polymeric and small molecule-conjugates of temozolomide as improved therapeutic agents for glioblastoma multiforme.
    Journal of controlled release : official journal of the Controlled Release Society, 2022, Volume: 350

    Topics: Alkylating Agents; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Delayed-Act

2022
Polymeric and small molecule-conjugates of temozolomide as improved therapeutic agents for glioblastoma multiforme.
    Journal of controlled release : official journal of the Controlled Release Society, 2022, Volume: 350

    Topics: Alkylating Agents; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Delayed-Act

2022
Current Opportunities for Targeting Dysregulated Neurodevelopmental Signaling Pathways in Glioblastoma.
    Cells, 2022, 08-15, Volume: 11, Issue:16

    Topics: Brain Neoplasms; Glioblastoma; Humans; Signal Transduction; Temozolomide

2022
Current Opportunities for Targeting Dysregulated Neurodevelopmental Signaling Pathways in Glioblastoma.
    Cells, 2022, 08-15, Volume: 11, Issue:16

    Topics: Brain Neoplasms; Glioblastoma; Humans; Signal Transduction; Temozolomide

2022
Current Opportunities for Targeting Dysregulated Neurodevelopmental Signaling Pathways in Glioblastoma.
    Cells, 2022, 08-15, Volume: 11, Issue:16

    Topics: Brain Neoplasms; Glioblastoma; Humans; Signal Transduction; Temozolomide

2022
Progress in research and development of temozolomide brain-targeted preparations: a review.
    Journal of drug targeting, 2023, Volume: 31, Issue:2

    Topics: Antineoplastic Agents, Alkylating; Brain; Brain Neoplasms; Cell Line, Tumor; Drug Resistance, Neopla

2023
Progress in research and development of temozolomide brain-targeted preparations: a review.
    Journal of drug targeting, 2023, Volume: 31, Issue:2

    Topics: Antineoplastic Agents, Alkylating; Brain; Brain Neoplasms; Cell Line, Tumor; Drug Resistance, Neopla

2023
Progress in research and development of temozolomide brain-targeted preparations: a review.
    Journal of drug targeting, 2023, Volume: 31, Issue:2

    Topics: Antineoplastic Agents, Alkylating; Brain; Brain Neoplasms; Cell Line, Tumor; Drug Resistance, Neopla

2023
Current and promising treatment strategies in glioma.
    Reviews in the neurosciences, 2023, Jul-26, Volume: 34, Issue:5

    Topics: Brain Neoplasms; Glioma; Humans; Immunotherapy; Mutation; Precision Medicine; Temozolomide

2023
Current and promising treatment strategies in glioma.
    Reviews in the neurosciences, 2023, Jul-26, Volume: 34, Issue:5

    Topics: Brain Neoplasms; Glioma; Humans; Immunotherapy; Mutation; Precision Medicine; Temozolomide

2023
Current and promising treatment strategies in glioma.
    Reviews in the neurosciences, 2023, Jul-26, Volume: 34, Issue:5

    Topics: Brain Neoplasms; Glioma; Humans; Immunotherapy; Mutation; Precision Medicine; Temozolomide

2023
MicroRNAs, Key Regulators in Glioma Progression as Potential Therapeutic Targets for Chinese Medicine.
    The American journal of Chinese medicine, 2022, Volume: 50, Issue:7

    Topics: Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Glioma; Humans; Medicine, Chinese

2022
MicroRNAs, Key Regulators in Glioma Progression as Potential Therapeutic Targets for Chinese Medicine.
    The American journal of Chinese medicine, 2022, Volume: 50, Issue:7

    Topics: Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Glioma; Humans; Medicine, Chinese

2022
MicroRNAs, Key Regulators in Glioma Progression as Potential Therapeutic Targets for Chinese Medicine.
    The American journal of Chinese medicine, 2022, Volume: 50, Issue:7

    Topics: Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Glioma; Humans; Medicine, Chinese

2022
Treatment Options for Recurrent Primary CNS Lymphoma.
    Current treatment options in oncology, 2022, Volume: 23, Issue:11

    Topics: Agammaglobulinaemia Tyrosine Kinase; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms

2022
Treatment Options for Recurrent Primary CNS Lymphoma.
    Current treatment options in oncology, 2022, Volume: 23, Issue:11

    Topics: Agammaglobulinaemia Tyrosine Kinase; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms

2022
Treatment Options for Recurrent Primary CNS Lymphoma.
    Current treatment options in oncology, 2022, Volume: 23, Issue:11

    Topics: Agammaglobulinaemia Tyrosine Kinase; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms

2022
Tumor treating fields with radiation for glioblastoma: a narrative review.
    Chinese clinical oncology, 2022, Volume: 11, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Glioblastoma; Humans; Temozol

2022
Tumor treating fields with radiation for glioblastoma: a narrative review.
    Chinese clinical oncology, 2022, Volume: 11, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Glioblastoma; Humans; Temozol

2022
Tumor treating fields with radiation for glioblastoma: a narrative review.
    Chinese clinical oncology, 2022, Volume: 11, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Glioblastoma; Humans; Temozol

2022
Moderately hypofractionated versus conventionally fractionated radiation therapy with temozolomide for young and fit patients with glioblastoma: an institutional experience and meta-analysis of literature.
    Journal of neuro-oncology, 2022, Volume: 160, Issue:2

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; COVID-19; Glioblastoma; Humans; Middle Aged; Pan

2022
Moderately hypofractionated versus conventionally fractionated radiation therapy with temozolomide for young and fit patients with glioblastoma: an institutional experience and meta-analysis of literature.
    Journal of neuro-oncology, 2022, Volume: 160, Issue:2

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; COVID-19; Glioblastoma; Humans; Middle Aged; Pan

2022
Moderately hypofractionated versus conventionally fractionated radiation therapy with temozolomide for young and fit patients with glioblastoma: an institutional experience and meta-analysis of literature.
    Journal of neuro-oncology, 2022, Volume: 160, Issue:2

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; COVID-19; Glioblastoma; Humans; Middle Aged; Pan

2022
The use of temozolomide in paediatric metastatic phaeochromocytoma/paraganglioma: A case report and literature review.
    Frontiers in endocrinology, 2022, Volume: 13

    Topics: Adrenal Gland Neoplasms; Adult; Brain Neoplasms; Child; Female; Humans; Neoplasms, Second Primary; P

2022
The use of temozolomide in paediatric metastatic phaeochromocytoma/paraganglioma: A case report and literature review.
    Frontiers in endocrinology, 2022, Volume: 13

    Topics: Adrenal Gland Neoplasms; Adult; Brain Neoplasms; Child; Female; Humans; Neoplasms, Second Primary; P

2022
The use of temozolomide in paediatric metastatic phaeochromocytoma/paraganglioma: A case report and literature review.
    Frontiers in endocrinology, 2022, Volume: 13

    Topics: Adrenal Gland Neoplasms; Adult; Brain Neoplasms; Child; Female; Humans; Neoplasms, Second Primary; P

2022
The use of temozolomide in paediatric metastatic phaeochromocytoma/paraganglioma: A case report and literature review.
    Frontiers in endocrinology, 2022, Volume: 13

    Topics: Adrenal Gland Neoplasms; Adult; Brain Neoplasms; Child; Female; Humans; Neoplasms, Second Primary; P

2022
The use of temozolomide in paediatric metastatic phaeochromocytoma/paraganglioma: A case report and literature review.
    Frontiers in endocrinology, 2022, Volume: 13

    Topics: Adrenal Gland Neoplasms; Adult; Brain Neoplasms; Child; Female; Humans; Neoplasms, Second Primary; P

2022
The use of temozolomide in paediatric metastatic phaeochromocytoma/paraganglioma: A case report and literature review.
    Frontiers in endocrinology, 2022, Volume: 13

    Topics: Adrenal Gland Neoplasms; Adult; Brain Neoplasms; Child; Female; Humans; Neoplasms, Second Primary; P

2022
The use of temozolomide in paediatric metastatic phaeochromocytoma/paraganglioma: A case report and literature review.
    Frontiers in endocrinology, 2022, Volume: 13

    Topics: Adrenal Gland Neoplasms; Adult; Brain Neoplasms; Child; Female; Humans; Neoplasms, Second Primary; P

2022
The use of temozolomide in paediatric metastatic phaeochromocytoma/paraganglioma: A case report and literature review.
    Frontiers in endocrinology, 2022, Volume: 13

    Topics: Adrenal Gland Neoplasms; Adult; Brain Neoplasms; Child; Female; Humans; Neoplasms, Second Primary; P

2022
The use of temozolomide in paediatric metastatic phaeochromocytoma/paraganglioma: A case report and literature review.
    Frontiers in endocrinology, 2022, Volume: 13

    Topics: Adrenal Gland Neoplasms; Adult; Brain Neoplasms; Child; Female; Humans; Neoplasms, Second Primary; P

2022
The use of temozolomide in paediatric metastatic phaeochromocytoma/paraganglioma: A case report and literature review.
    Frontiers in endocrinology, 2022, Volume: 13

    Topics: Adrenal Gland Neoplasms; Adult; Brain Neoplasms; Child; Female; Humans; Neoplasms, Second Primary; P

2022
The use of temozolomide in paediatric metastatic phaeochromocytoma/paraganglioma: A case report and literature review.
    Frontiers in endocrinology, 2022, Volume: 13

    Topics: Adrenal Gland Neoplasms; Adult; Brain Neoplasms; Child; Female; Humans; Neoplasms, Second Primary; P

2022
The use of temozolomide in paediatric metastatic phaeochromocytoma/paraganglioma: A case report and literature review.
    Frontiers in endocrinology, 2022, Volume: 13

    Topics: Adrenal Gland Neoplasms; Adult; Brain Neoplasms; Child; Female; Humans; Neoplasms, Second Primary; P

2022
Iron Oxide Nanoparticles Decorated with Functional Peptides for a Targeted siRNA Delivery to Glioma Cells.
    ACS applied materials & interfaces, 2023, Jan-11, Volume: 15, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Dacarbazine; Drug Resistance,

2023
Iron Oxide Nanoparticles Decorated with Functional Peptides for a Targeted siRNA Delivery to Glioma Cells.
    ACS applied materials & interfaces, 2023, Jan-11, Volume: 15, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Dacarbazine; Drug Resistance,

2023
Iron Oxide Nanoparticles Decorated with Functional Peptides for a Targeted siRNA Delivery to Glioma Cells.
    ACS applied materials & interfaces, 2023, Jan-11, Volume: 15, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Dacarbazine; Drug Resistance,

2023
Iron Oxide Nanoparticles Decorated with Functional Peptides for a Targeted siRNA Delivery to Glioma Cells.
    ACS applied materials & interfaces, 2023, Jan-11, Volume: 15, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Dacarbazine; Drug Resistance,

2023
Iron Oxide Nanoparticles Decorated with Functional Peptides for a Targeted siRNA Delivery to Glioma Cells.
    ACS applied materials & interfaces, 2023, Jan-11, Volume: 15, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Dacarbazine; Drug Resistance,

2023
Iron Oxide Nanoparticles Decorated with Functional Peptides for a Targeted siRNA Delivery to Glioma Cells.
    ACS applied materials & interfaces, 2023, Jan-11, Volume: 15, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Dacarbazine; Drug Resistance,

2023
Iron Oxide Nanoparticles Decorated with Functional Peptides for a Targeted siRNA Delivery to Glioma Cells.
    ACS applied materials & interfaces, 2023, Jan-11, Volume: 15, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Dacarbazine; Drug Resistance,

2023
Iron Oxide Nanoparticles Decorated with Functional Peptides for a Targeted siRNA Delivery to Glioma Cells.
    ACS applied materials & interfaces, 2023, Jan-11, Volume: 15, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Dacarbazine; Drug Resistance,

2023
Iron Oxide Nanoparticles Decorated with Functional Peptides for a Targeted siRNA Delivery to Glioma Cells.
    ACS applied materials & interfaces, 2023, Jan-11, Volume: 15, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Dacarbazine; Drug Resistance,

2023
Iron Oxide Nanoparticles Decorated with Functional Peptides for a Targeted siRNA Delivery to Glioma Cells.
    ACS applied materials & interfaces, 2023, Jan-11, Volume: 15, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Dacarbazine; Drug Resistance,

2023
Iron Oxide Nanoparticles Decorated with Functional Peptides for a Targeted siRNA Delivery to Glioma Cells.
    ACS applied materials & interfaces, 2023, Jan-11, Volume: 15, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Dacarbazine; Drug Resistance,

2023
Iron Oxide Nanoparticles Decorated with Functional Peptides for a Targeted siRNA Delivery to Glioma Cells.
    ACS applied materials & interfaces, 2023, Jan-11, Volume: 15, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Dacarbazine; Drug Resistance,

2023
Most recent update of preclinical and clinical data on radioresistance and radiosensitivity of high-grade gliomas-a radiation oncologist's perspective.
    Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 2023, Volume: 199, Issue:1

    Topics: Brain Neoplasms; Clinical Trials as Topic; Glioma; Humans; Radiation Oncologists; Radiation Toleranc

2023
Most recent update of preclinical and clinical data on radioresistance and radiosensitivity of high-grade gliomas-a radiation oncologist's perspective.
    Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 2023, Volume: 199, Issue:1

    Topics: Brain Neoplasms; Clinical Trials as Topic; Glioma; Humans; Radiation Oncologists; Radiation Toleranc

2023
Most recent update of preclinical and clinical data on radioresistance and radiosensitivity of high-grade gliomas-a radiation oncologist's perspective.
    Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 2023, Volume: 199, Issue:1

    Topics: Brain Neoplasms; Clinical Trials as Topic; Glioma; Humans; Radiation Oncologists; Radiation Toleranc

2023
Most recent update of preclinical and clinical data on radioresistance and radiosensitivity of high-grade gliomas-a radiation oncologist's perspective.
    Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 2023, Volume: 199, Issue:1

    Topics: Brain Neoplasms; Clinical Trials as Topic; Glioma; Humans; Radiation Oncologists; Radiation Toleranc

2023
Most recent update of preclinical and clinical data on radioresistance and radiosensitivity of high-grade gliomas-a radiation oncologist's perspective.
    Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 2023, Volume: 199, Issue:1

    Topics: Brain Neoplasms; Clinical Trials as Topic; Glioma; Humans; Radiation Oncologists; Radiation Toleranc

2023
Most recent update of preclinical and clinical data on radioresistance and radiosensitivity of high-grade gliomas-a radiation oncologist's perspective.
    Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 2023, Volume: 199, Issue:1

    Topics: Brain Neoplasms; Clinical Trials as Topic; Glioma; Humans; Radiation Oncologists; Radiation Toleranc

2023
Most recent update of preclinical and clinical data on radioresistance and radiosensitivity of high-grade gliomas-a radiation oncologist's perspective.
    Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 2023, Volume: 199, Issue:1

    Topics: Brain Neoplasms; Clinical Trials as Topic; Glioma; Humans; Radiation Oncologists; Radiation Toleranc

2023
Most recent update of preclinical and clinical data on radioresistance and radiosensitivity of high-grade gliomas-a radiation oncologist's perspective.
    Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 2023, Volume: 199, Issue:1

    Topics: Brain Neoplasms; Clinical Trials as Topic; Glioma; Humans; Radiation Oncologists; Radiation Toleranc

2023
Most recent update of preclinical and clinical data on radioresistance and radiosensitivity of high-grade gliomas-a radiation oncologist's perspective.
    Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 2023, Volume: 199, Issue:1

    Topics: Brain Neoplasms; Clinical Trials as Topic; Glioma; Humans; Radiation Oncologists; Radiation Toleranc

2023
Most recent update of preclinical and clinical data on radioresistance and radiosensitivity of high-grade gliomas-a radiation oncologist's perspective.
    Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 2023, Volume: 199, Issue:1

    Topics: Brain Neoplasms; Clinical Trials as Topic; Glioma; Humans; Radiation Oncologists; Radiation Toleranc

2023
Most recent update of preclinical and clinical data on radioresistance and radiosensitivity of high-grade gliomas-a radiation oncologist's perspective.
    Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 2023, Volume: 199, Issue:1

    Topics: Brain Neoplasms; Clinical Trials as Topic; Glioma; Humans; Radiation Oncologists; Radiation Toleranc

2023
Most recent update of preclinical and clinical data on radioresistance and radiosensitivity of high-grade gliomas-a radiation oncologist's perspective.
    Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 2023, Volume: 199, Issue:1

    Topics: Brain Neoplasms; Clinical Trials as Topic; Glioma; Humans; Radiation Oncologists; Radiation Toleranc

2023
Utility of the Cerebral Organoid Glioma 'GLICO' Model for Screening Applications.
    Cells, 2022, 12-30, Volume: 12, Issue:1

    Topics: Brain Neoplasms; Glioblastoma; Humans; Neoplasm Recurrence, Local; Organoids; Temozolomide

2022
Utility of the Cerebral Organoid Glioma 'GLICO' Model for Screening Applications.
    Cells, 2022, 12-30, Volume: 12, Issue:1

    Topics: Brain Neoplasms; Glioblastoma; Humans; Neoplasm Recurrence, Local; Organoids; Temozolomide

2022
Utility of the Cerebral Organoid Glioma 'GLICO' Model for Screening Applications.
    Cells, 2022, 12-30, Volume: 12, Issue:1

    Topics: Brain Neoplasms; Glioblastoma; Humans; Neoplasm Recurrence, Local; Organoids; Temozolomide

2022
Objective response rate targets for recurrent glioblastoma clinical trials based on the historic association between objective response rate and median overall survival.
    Neuro-oncology, 2023, 06-02, Volume: 25, Issue:6

    Topics: Angiogenesis Inhibitors; Antineoplastic Agents; Brain Neoplasms; Glioblastoma; Humans; Lomustine; Ne

2023
Objective response rate targets for recurrent glioblastoma clinical trials based on the historic association between objective response rate and median overall survival.
    Neuro-oncology, 2023, 06-02, Volume: 25, Issue:6

    Topics: Angiogenesis Inhibitors; Antineoplastic Agents; Brain Neoplasms; Glioblastoma; Humans; Lomustine; Ne

2023
Objective response rate targets for recurrent glioblastoma clinical trials based on the historic association between objective response rate and median overall survival.
    Neuro-oncology, 2023, 06-02, Volume: 25, Issue:6

    Topics: Angiogenesis Inhibitors; Antineoplastic Agents; Brain Neoplasms; Glioblastoma; Humans; Lomustine; Ne

2023
Injectable local drug delivery systems for glioblastoma: a systematic review and
    Biomaterials science, 2023, Feb-28, Volume: 11, Issue:5

    Topics: Animals; Brain Neoplasms; Drug Delivery Systems; Glioblastoma; Liposomes; Temozolomide

2023
Injectable local drug delivery systems for glioblastoma: a systematic review and
    Biomaterials science, 2023, Feb-28, Volume: 11, Issue:5

    Topics: Animals; Brain Neoplasms; Drug Delivery Systems; Glioblastoma; Liposomes; Temozolomide

2023
Injectable local drug delivery systems for glioblastoma: a systematic review and
    Biomaterials science, 2023, Feb-28, Volume: 11, Issue:5

    Topics: Animals; Brain Neoplasms; Drug Delivery Systems; Glioblastoma; Liposomes; Temozolomide

2023
Modeling glioblastoma complexity with organoids for personalized treatments.
    Trends in molecular medicine, 2023, Volume: 29, Issue:4

    Topics: Brain Neoplasms; Cell Culture Techniques; Cell Line, Tumor; Drug Resistance, Neoplasm; Glioblastoma;

2023
Modeling glioblastoma complexity with organoids for personalized treatments.
    Trends in molecular medicine, 2023, Volume: 29, Issue:4

    Topics: Brain Neoplasms; Cell Culture Techniques; Cell Line, Tumor; Drug Resistance, Neoplasm; Glioblastoma;

2023
Modeling glioblastoma complexity with organoids for personalized treatments.
    Trends in molecular medicine, 2023, Volume: 29, Issue:4

    Topics: Brain Neoplasms; Cell Culture Techniques; Cell Line, Tumor; Drug Resistance, Neoplasm; Glioblastoma;

2023
Glioblastoma and Other Primary Brain Malignancies in Adults: A Review.
    JAMA, 2023, 02-21, Volume: 329, Issue:7

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Brain; Brain Neoplasms; Glioblastoma; Glioma;

2023
Glioblastoma and Other Primary Brain Malignancies in Adults: A Review.
    JAMA, 2023, 02-21, Volume: 329, Issue:7

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Brain; Brain Neoplasms; Glioblastoma; Glioma;

2023
Glioblastoma and Other Primary Brain Malignancies in Adults: A Review.
    JAMA, 2023, 02-21, Volume: 329, Issue:7

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Brain; Brain Neoplasms; Glioblastoma; Glioma;

2023
Temozolomide Chronotherapy in Glioma: A Systematic Review.
    Current oncology (Toronto, Ont.), 2023, 02-04, Volume: 30, Issue:2

    Topics: Brain Neoplasms; Chronotherapy; Glioma; Humans; Prospective Studies; Randomized Controlled Trials as

2023
Temozolomide Chronotherapy in Glioma: A Systematic Review.
    Current oncology (Toronto, Ont.), 2023, 02-04, Volume: 30, Issue:2

    Topics: Brain Neoplasms; Chronotherapy; Glioma; Humans; Prospective Studies; Randomized Controlled Trials as

2023
Temozolomide Chronotherapy in Glioma: A Systematic Review.
    Current oncology (Toronto, Ont.), 2023, 02-04, Volume: 30, Issue:2

    Topics: Brain Neoplasms; Chronotherapy; Glioma; Humans; Prospective Studies; Randomized Controlled Trials as

2023
Is Autophagy Inhibition in Combination with Temozolomide a Therapeutically Viable Strategy?
    Cells, 2023, 02-07, Volume: 12, Issue:4

    Topics: Autophagy; Brain Neoplasms; Glioblastoma; Humans; Neoplasm Recurrence, Local; Temozolomide

2023
Is Autophagy Inhibition in Combination with Temozolomide a Therapeutically Viable Strategy?
    Cells, 2023, 02-07, Volume: 12, Issue:4

    Topics: Autophagy; Brain Neoplasms; Glioblastoma; Humans; Neoplasm Recurrence, Local; Temozolomide

2023
Is Autophagy Inhibition in Combination with Temozolomide a Therapeutically Viable Strategy?
    Cells, 2023, 02-07, Volume: 12, Issue:4

    Topics: Autophagy; Brain Neoplasms; Glioblastoma; Humans; Neoplasm Recurrence, Local; Temozolomide

2023
The Role of Long Noncoding Ribonucleic Acids in Glioblastoma: What the Neurosurgeon Should Know.
    Neurosurgery, 2023, 06-01, Volume: 92, Issue:6

    Topics: Brain Neoplasms; Gene Expression Regulation, Neoplastic; Glioblastoma; Humans; Neurosurgeons; RNA, L

2023
The Role of Long Noncoding Ribonucleic Acids in Glioblastoma: What the Neurosurgeon Should Know.
    Neurosurgery, 2023, 06-01, Volume: 92, Issue:6

    Topics: Brain Neoplasms; Gene Expression Regulation, Neoplastic; Glioblastoma; Humans; Neurosurgeons; RNA, L

2023
The Role of Long Noncoding Ribonucleic Acids in Glioblastoma: What the Neurosurgeon Should Know.
    Neurosurgery, 2023, 06-01, Volume: 92, Issue:6

    Topics: Brain Neoplasms; Gene Expression Regulation, Neoplastic; Glioblastoma; Humans; Neurosurgeons; RNA, L

2023
Radiotherapy, lymphopenia and improving the outcome for glioblastoma: a narrative review.
    Chinese clinical oncology, 2023, Volume: 12, Issue:1

    Topics: Brain Neoplasms; Glioblastoma; Humans; Lymphopenia; Radiotherapy; Temozolomide; Treatment Outcome

2023
Radiotherapy, lymphopenia and improving the outcome for glioblastoma: a narrative review.
    Chinese clinical oncology, 2023, Volume: 12, Issue:1

    Topics: Brain Neoplasms; Glioblastoma; Humans; Lymphopenia; Radiotherapy; Temozolomide; Treatment Outcome

2023
Radiotherapy, lymphopenia and improving the outcome for glioblastoma: a narrative review.
    Chinese clinical oncology, 2023, Volume: 12, Issue:1

    Topics: Brain Neoplasms; Glioblastoma; Humans; Lymphopenia; Radiotherapy; Temozolomide; Treatment Outcome

2023
Advanced Bioinformatics Analysis and Genetic Technologies for Targeting Autophagy in Glioblastoma Multiforme.
    Cells, 2023, 03-15, Volume: 12, Issue:6

    Topics: Adult; Autophagy; Brain Neoplasms; Glioblastoma; Humans; MicroRNAs; Temozolomide; Tumor Microenviron

2023
Advanced Bioinformatics Analysis and Genetic Technologies for Targeting Autophagy in Glioblastoma Multiforme.
    Cells, 2023, 03-15, Volume: 12, Issue:6

    Topics: Adult; Autophagy; Brain Neoplasms; Glioblastoma; Humans; MicroRNAs; Temozolomide; Tumor Microenviron

2023
Advanced Bioinformatics Analysis and Genetic Technologies for Targeting Autophagy in Glioblastoma Multiforme.
    Cells, 2023, 03-15, Volume: 12, Issue:6

    Topics: Adult; Autophagy; Brain Neoplasms; Glioblastoma; Humans; MicroRNAs; Temozolomide; Tumor Microenviron

2023
Target-Based Anticancer Indole Derivatives for the Development of Anti-Glioblastoma Agents.
    Molecules (Basel, Switzerland), 2023, Mar-13, Volume: 28, Issue:6

    Topics: Brain Neoplasms; Glioblastoma; Humans; Indoles; Temozolomide

2023
Target-Based Anticancer Indole Derivatives for the Development of Anti-Glioblastoma Agents.
    Molecules (Basel, Switzerland), 2023, Mar-13, Volume: 28, Issue:6

    Topics: Brain Neoplasms; Glioblastoma; Humans; Indoles; Temozolomide

2023
Target-Based Anticancer Indole Derivatives for the Development of Anti-Glioblastoma Agents.
    Molecules (Basel, Switzerland), 2023, Mar-13, Volume: 28, Issue:6

    Topics: Brain Neoplasms; Glioblastoma; Humans; Indoles; Temozolomide

2023
Expert opinion on translational research for advanced glioblastoma treatment.
    Cancer biology & medicine, 2023, 04-25, Volume: 20, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Expert Testimony; Glioblastoma; Glioma; Humans;

2023
Expert opinion on translational research for advanced glioblastoma treatment.
    Cancer biology & medicine, 2023, 04-25, Volume: 20, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Expert Testimony; Glioblastoma; Glioma; Humans;

2023
Expert opinion on translational research for advanced glioblastoma treatment.
    Cancer biology & medicine, 2023, 04-25, Volume: 20, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Expert Testimony; Glioblastoma; Glioma; Humans;

2023
Advances in Treatment of Isocitrate Dehydrogenase (IDH)-Wildtype Glioblastomas.
    Current neurology and neuroscience reports, 2023, Volume: 23, Issue:6

    Topics: Brain Neoplasms; Glioblastoma; Humans; Immunotherapy; Isocitrate Dehydrogenase; Mutation; Prognosis;

2023
Advances in Treatment of Isocitrate Dehydrogenase (IDH)-Wildtype Glioblastomas.
    Current neurology and neuroscience reports, 2023, Volume: 23, Issue:6

    Topics: Brain Neoplasms; Glioblastoma; Humans; Immunotherapy; Isocitrate Dehydrogenase; Mutation; Prognosis;

2023
Advances in Treatment of Isocitrate Dehydrogenase (IDH)-Wildtype Glioblastomas.
    Current neurology and neuroscience reports, 2023, Volume: 23, Issue:6

    Topics: Brain Neoplasms; Glioblastoma; Humans; Immunotherapy; Isocitrate Dehydrogenase; Mutation; Prognosis;

2023
Pyroptosis, ferroptosis, and autophagy cross-talk in glioblastoma opens up new avenues for glioblastoma treatment.
    Cell communication and signaling : CCS, 2023, 05-19, Volume: 21, Issue:1

    Topics: Apoptosis; Autophagy; Brain Neoplasms; Cell Line, Tumor; Ferroptosis; Glioblastoma; Humans; Pyroptos

2023
Pyroptosis, ferroptosis, and autophagy cross-talk in glioblastoma opens up new avenues for glioblastoma treatment.
    Cell communication and signaling : CCS, 2023, 05-19, Volume: 21, Issue:1

    Topics: Apoptosis; Autophagy; Brain Neoplasms; Cell Line, Tumor; Ferroptosis; Glioblastoma; Humans; Pyroptos

2023
Pyroptosis, ferroptosis, and autophagy cross-talk in glioblastoma opens up new avenues for glioblastoma treatment.
    Cell communication and signaling : CCS, 2023, 05-19, Volume: 21, Issue:1

    Topics: Apoptosis; Autophagy; Brain Neoplasms; Cell Line, Tumor; Ferroptosis; Glioblastoma; Humans; Pyroptos

2023
Novel sights on therapeutic, prognostic, and diagnostics aspects of non-coding RNAs in glioblastoma multiforme.
    Metabolic brain disease, 2023, Volume: 38, Issue:6

    Topics: Brain Neoplasms; Cell Line, Tumor; Glioblastoma; Humans; MicroRNAs; Precision Medicine; Prognosis; T

2023
Novel sights on therapeutic, prognostic, and diagnostics aspects of non-coding RNAs in glioblastoma multiforme.
    Metabolic brain disease, 2023, Volume: 38, Issue:6

    Topics: Brain Neoplasms; Cell Line, Tumor; Glioblastoma; Humans; MicroRNAs; Precision Medicine; Prognosis; T

2023
Novel sights on therapeutic, prognostic, and diagnostics aspects of non-coding RNAs in glioblastoma multiforme.
    Metabolic brain disease, 2023, Volume: 38, Issue:6

    Topics: Brain Neoplasms; Cell Line, Tumor; Glioblastoma; Humans; MicroRNAs; Precision Medicine; Prognosis; T

2023
Nitric oxide synthase inhibitors as potential therapeutic agents for gliomas: A systematic review.
    Nitric oxide : biology and chemistry, 2023, 09-01, Volume: 138-139

    Topics: Animals; Brain Neoplasms; Enzyme Inhibitors; Glioblastoma; Glioma; Humans; NG-Nitroarginine Methyl E

2023
Nitric oxide synthase inhibitors as potential therapeutic agents for gliomas: A systematic review.
    Nitric oxide : biology and chemistry, 2023, 09-01, Volume: 138-139

    Topics: Animals; Brain Neoplasms; Enzyme Inhibitors; Glioblastoma; Glioma; Humans; NG-Nitroarginine Methyl E

2023
Nitric oxide synthase inhibitors as potential therapeutic agents for gliomas: A systematic review.
    Nitric oxide : biology and chemistry, 2023, 09-01, Volume: 138-139

    Topics: Animals; Brain Neoplasms; Enzyme Inhibitors; Glioblastoma; Glioma; Humans; NG-Nitroarginine Methyl E

2023
Current advances in temozolomide encapsulation for the enhancement of glioblastoma treatment.
    Theranostics, 2023, Volume: 13, Issue:9

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; End

2023
Current advances in temozolomide encapsulation for the enhancement of glioblastoma treatment.
    Theranostics, 2023, Volume: 13, Issue:9

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; End

2023
Current advances in temozolomide encapsulation for the enhancement of glioblastoma treatment.
    Theranostics, 2023, Volume: 13, Issue:9

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; End

2023
The impact of survivorship bias in glioblastoma research.
    Critical reviews in oncology/hematology, 2023, Volume: 188

    Topics: Aged; Biomarkers, Tumor; Brain Neoplasms; Dacarbazine; DNA Methylation; DNA Repair Enzymes; Glioblas

2023
The impact of survivorship bias in glioblastoma research.
    Critical reviews in oncology/hematology, 2023, Volume: 188

    Topics: Aged; Biomarkers, Tumor; Brain Neoplasms; Dacarbazine; DNA Methylation; DNA Repair Enzymes; Glioblas

2023
The impact of survivorship bias in glioblastoma research.
    Critical reviews in oncology/hematology, 2023, Volume: 188

    Topics: Aged; Biomarkers, Tumor; Brain Neoplasms; Dacarbazine; DNA Methylation; DNA Repair Enzymes; Glioblas

2023
Strategies increasing the effectiveness of temozolomide at various levels of anti-GBL therapy.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2023, Volume: 165

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Glioblastoma; Glioma; Humans; Temoz

2023
Strategies increasing the effectiveness of temozolomide at various levels of anti-GBL therapy.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2023, Volume: 165

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Glioblastoma; Glioma; Humans; Temoz

2023
Strategies increasing the effectiveness of temozolomide at various levels of anti-GBL therapy.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2023, Volume: 165

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Glioblastoma; Glioma; Humans; Temoz

2023
Glioblastoma Multiforme: The Latest Diagnostics and Treatment Techniques.
    Pharmacology, 2023, Volume: 108, Issue:5

    Topics: Brain Neoplasms; Glioblastoma; Glioma; Humans; Oncolytic Virotherapy; Temozolomide

2023
Glioblastoma Multiforme: The Latest Diagnostics and Treatment Techniques.
    Pharmacology, 2023, Volume: 108, Issue:5

    Topics: Brain Neoplasms; Glioblastoma; Glioma; Humans; Oncolytic Virotherapy; Temozolomide

2023
Glioblastoma Multiforme: The Latest Diagnostics and Treatment Techniques.
    Pharmacology, 2023, Volume: 108, Issue:5

    Topics: Brain Neoplasms; Glioblastoma; Glioma; Humans; Oncolytic Virotherapy; Temozolomide

2023
Association of Tumor Treating Fields (TTFields) therapy with survival in newly diagnosed glioblastoma: a systematic review and meta-analysis.
    Journal of neuro-oncology, 2023, Volume: 164, Issue:1

    Topics: Brain Neoplasms; Combined Modality Therapy; Electric Stimulation Therapy; Glioblastoma; Humans; Temo

2023
Association of Tumor Treating Fields (TTFields) therapy with survival in newly diagnosed glioblastoma: a systematic review and meta-analysis.
    Journal of neuro-oncology, 2023, Volume: 164, Issue:1

    Topics: Brain Neoplasms; Combined Modality Therapy; Electric Stimulation Therapy; Glioblastoma; Humans; Temo

2023
Association of Tumor Treating Fields (TTFields) therapy with survival in newly diagnosed glioblastoma: a systematic review and meta-analysis.
    Journal of neuro-oncology, 2023, Volume: 164, Issue:1

    Topics: Brain Neoplasms; Combined Modality Therapy; Electric Stimulation Therapy; Glioblastoma; Humans; Temo

2023
Epigenetic regulation of temozolomide resistance in human cancers with an emphasis on brain tumors: Function of non-coding RNAs.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2023, Volume: 165

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; Epi

2023
Epigenetic regulation of temozolomide resistance in human cancers with an emphasis on brain tumors: Function of non-coding RNAs.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2023, Volume: 165

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; Epi

2023
Epigenetic regulation of temozolomide resistance in human cancers with an emphasis on brain tumors: Function of non-coding RNAs.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2023, Volume: 165

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; Epi

2023
Dysregulated lipid metabolism in TMZ-resistant glioblastoma: pathways, proteins, metabolites and therapeutic opportunities.
    Lipids in health and disease, 2023, Aug-03, Volume: 22, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; Gli

2023
Dysregulated lipid metabolism in TMZ-resistant glioblastoma: pathways, proteins, metabolites and therapeutic opportunities.
    Lipids in health and disease, 2023, Aug-03, Volume: 22, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; Gli

2023
Dysregulated lipid metabolism in TMZ-resistant glioblastoma: pathways, proteins, metabolites and therapeutic opportunities.
    Lipids in health and disease, 2023, Aug-03, Volume: 22, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; Gli

2023
Efficacy of tumour-treating fields therapy in recurrent glioblastoma: A narrative review of current evidence.
    Medicine, 2023, Dec-01, Volume: 102, Issue:48

    Topics: Brain Neoplasms; Combined Modality Therapy; Electric Stimulation Therapy; Glioblastoma; Humans; Temo

2023
Efficacy of tumour-treating fields therapy in recurrent glioblastoma: A narrative review of current evidence.
    Medicine, 2023, Dec-01, Volume: 102, Issue:48

    Topics: Brain Neoplasms; Combined Modality Therapy; Electric Stimulation Therapy; Glioblastoma; Humans; Temo

2023
Efficacy of tumour-treating fields therapy in recurrent glioblastoma: A narrative review of current evidence.
    Medicine, 2023, Dec-01, Volume: 102, Issue:48

    Topics: Brain Neoplasms; Combined Modality Therapy; Electric Stimulation Therapy; Glioblastoma; Humans; Temo

2023
Radiation and chemotherapy for high-risk lower grade gliomas: Choosing between temozolomide and PCV.
    Cancer medicine, 2020, Volume: 9, Issue:1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Brain; Brain Neoplasms; Chemoradiotherapy, Adjuvant;

2020
Radiation and chemotherapy for high-risk lower grade gliomas: Choosing between temozolomide and PCV.
    Cancer medicine, 2020, Volume: 9, Issue:1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Brain; Brain Neoplasms; Chemoradiotherapy, Adjuvant;

2020
Radiation and chemotherapy for high-risk lower grade gliomas: Choosing between temozolomide and PCV.
    Cancer medicine, 2020, Volume: 9, Issue:1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Brain; Brain Neoplasms; Chemoradiotherapy, Adjuvant;

2020
Prognosis of patients with newly diagnosed glioblastoma treated with molecularly targeted drugs combined with radiotherapy vs temozolomide monotherapy: A meta-analysis.
    Medicine, 2019, Volume: 98, Issue:45

    Topics: Brain Neoplasms; Chemoradiotherapy; Female; Glioblastoma; Humans; Male; Molecular Targeted Therapy;

2019
Prognosis of patients with newly diagnosed glioblastoma treated with molecularly targeted drugs combined with radiotherapy vs temozolomide monotherapy: A meta-analysis.
    Medicine, 2019, Volume: 98, Issue:45

    Topics: Brain Neoplasms; Chemoradiotherapy; Female; Glioblastoma; Humans; Male; Molecular Targeted Therapy;

2019
Prognosis of patients with newly diagnosed glioblastoma treated with molecularly targeted drugs combined with radiotherapy vs temozolomide monotherapy: A meta-analysis.
    Medicine, 2019, Volume: 98, Issue:45

    Topics: Brain Neoplasms; Chemoradiotherapy; Female; Glioblastoma; Humans; Male; Molecular Targeted Therapy;

2019
Focused Ultrasound Strategies for Brain Tumor Therapy.
    Operative neurosurgery (Hagerstown, Md.), 2020, 07-01, Volume: 19, Issue:1

    Topics: Animals; Blood-Brain Barrier; Brain; Brain Neoplasms; Glioma; Humans; Temozolomide

2020
Focused Ultrasound Strategies for Brain Tumor Therapy.
    Operative neurosurgery (Hagerstown, Md.), 2020, 07-01, Volume: 19, Issue:1

    Topics: Animals; Blood-Brain Barrier; Brain; Brain Neoplasms; Glioma; Humans; Temozolomide

2020
Focused Ultrasound Strategies for Brain Tumor Therapy.
    Operative neurosurgery (Hagerstown, Md.), 2020, 07-01, Volume: 19, Issue:1

    Topics: Animals; Blood-Brain Barrier; Brain; Brain Neoplasms; Glioma; Humans; Temozolomide

2020
Glioblastoma multiforme: a glance at advanced therapies based on nanotechnology.
    Journal of chemotherapy (Florence, Italy), 2020, Volume: 32, Issue:3

    Topics: Antineoplastic Agents; Blood-Brain Barrier; Brain Neoplasms; Chemistry, Pharmaceutical; Dendrimers;

2020
Glioblastoma multiforme: a glance at advanced therapies based on nanotechnology.
    Journal of chemotherapy (Florence, Italy), 2020, Volume: 32, Issue:3

    Topics: Antineoplastic Agents; Blood-Brain Barrier; Brain Neoplasms; Chemistry, Pharmaceutical; Dendrimers;

2020
Glioblastoma multiforme: a glance at advanced therapies based on nanotechnology.
    Journal of chemotherapy (Florence, Italy), 2020, Volume: 32, Issue:3

    Topics: Antineoplastic Agents; Blood-Brain Barrier; Brain Neoplasms; Chemistry, Pharmaceutical; Dendrimers;

2020
Steroids use and survival in patients with glioblastoma multiforme: a pooled analysis.
    Journal of neurology, 2021, Volume: 268, Issue:2

    Topics: Adult; Brain Neoplasms; Chemoradiotherapy; Disease-Free Survival; Glioblastoma; Humans; Prospective

2021
Steroids use and survival in patients with glioblastoma multiforme: a pooled analysis.
    Journal of neurology, 2021, Volume: 268, Issue:2

    Topics: Adult; Brain Neoplasms; Chemoradiotherapy; Disease-Free Survival; Glioblastoma; Humans; Prospective

2021
Steroids use and survival in patients with glioblastoma multiforme: a pooled analysis.
    Journal of neurology, 2021, Volume: 268, Issue:2

    Topics: Adult; Brain Neoplasms; Chemoradiotherapy; Disease-Free Survival; Glioblastoma; Humans; Prospective

2021
Therapeutic Application of PARP Inhibitors in Neuro-Oncology.
    Trends in cancer, 2020, Volume: 6, Issue:2

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Blood-Brain Barrier; Bra

2020
Therapeutic Application of PARP Inhibitors in Neuro-Oncology.
    Trends in cancer, 2020, Volume: 6, Issue:2

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Blood-Brain Barrier; Bra

2020
Therapeutic Application of PARP Inhibitors in Neuro-Oncology.
    Trends in cancer, 2020, Volume: 6, Issue:2

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Blood-Brain Barrier; Bra

2020
Management of glioblastomas in the elderly population.
    Revue neurologique, 2020, Volume: 176, Issue:9

    Topics: Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Glioblastoma; Humans; Prospective Studies;

2020
Management of glioblastomas in the elderly population.
    Revue neurologique, 2020, Volume: 176, Issue:9

    Topics: Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Glioblastoma; Humans; Prospective Studies;

2020
Management of glioblastomas in the elderly population.
    Revue neurologique, 2020, Volume: 176, Issue:9

    Topics: Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Glioblastoma; Humans; Prospective Studies;

2020
MGMT Status as a Clinical Biomarker in Glioblastoma.
    Trends in cancer, 2020, Volume: 6, Issue:5

    Topics: Biomarkers, Tumor; Brain Neoplasms; Clinical Decision-Making; DNA Methylation; DNA Mismatch Repair;

2020
MGMT Status as a Clinical Biomarker in Glioblastoma.
    Trends in cancer, 2020, Volume: 6, Issue:5

    Topics: Biomarkers, Tumor; Brain Neoplasms; Clinical Decision-Making; DNA Methylation; DNA Mismatch Repair;

2020
MGMT Status as a Clinical Biomarker in Glioblastoma.
    Trends in cancer, 2020, Volume: 6, Issue:5

    Topics: Biomarkers, Tumor; Brain Neoplasms; Clinical Decision-Making; DNA Methylation; DNA Mismatch Repair;

2020
Management of glioblastoma: State of the art and future directions.
    CA: a cancer journal for clinicians, 2020, Volume: 70, Issue:4

    Topics: Antineoplastic Agents; Bevacizumab; Brain; Brain Neoplasms; Chemoradiotherapy, Adjuvant; Glioblastom

2020
Management of glioblastoma: State of the art and future directions.
    CA: a cancer journal for clinicians, 2020, Volume: 70, Issue:4

    Topics: Antineoplastic Agents; Bevacizumab; Brain; Brain Neoplasms; Chemoradiotherapy, Adjuvant; Glioblastom

2020
Management of glioblastoma: State of the art and future directions.
    CA: a cancer journal for clinicians, 2020, Volume: 70, Issue:4

    Topics: Antineoplastic Agents; Bevacizumab; Brain; Brain Neoplasms; Chemoradiotherapy, Adjuvant; Glioblastom

2020
Temozolomide: An Updated Overview of Resistance Mechanisms, Nanotechnology Advances and Clinical Applications.
    Current neuropharmacology, 2021, Volume: 19, Issue:4

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Humans; Nanotechnology; Temozo

2021
Temozolomide: An Updated Overview of Resistance Mechanisms, Nanotechnology Advances and Clinical Applications.
    Current neuropharmacology, 2021, Volume: 19, Issue:4

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Humans; Nanotechnology; Temozo

2021
Temozolomide: An Updated Overview of Resistance Mechanisms, Nanotechnology Advances and Clinical Applications.
    Current neuropharmacology, 2021, Volume: 19, Issue:4

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Humans; Nanotechnology; Temozo

2021
The efficacy and safety of radiotherapy with adjuvant temozolomide for glioblastoma: A meta-analysis of randomized controlled studies.
    Clinical neurology and neurosurgery, 2020, Volume: 196

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant; Glioblastoma; Humans; Ra

2020
The efficacy and safety of radiotherapy with adjuvant temozolomide for glioblastoma: A meta-analysis of randomized controlled studies.
    Clinical neurology and neurosurgery, 2020, Volume: 196

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant; Glioblastoma; Humans; Ra

2020
The efficacy and safety of radiotherapy with adjuvant temozolomide for glioblastoma: A meta-analysis of randomized controlled studies.
    Clinical neurology and neurosurgery, 2020, Volume: 196

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant; Glioblastoma; Humans; Ra

2020
Targeting the DNA Damage Response to Overcome Cancer Drug Resistance in Glioblastoma.
    International journal of molecular sciences, 2020, Jul-11, Volume: 21, Issue:14

    Topics: Antineoplastic Agents; Ataxia Telangiectasia Mutated Proteins; Brain Neoplasms; Cell Line, Tumor; Cl

2020
Targeting the DNA Damage Response to Overcome Cancer Drug Resistance in Glioblastoma.
    International journal of molecular sciences, 2020, Jul-11, Volume: 21, Issue:14

    Topics: Antineoplastic Agents; Ataxia Telangiectasia Mutated Proteins; Brain Neoplasms; Cell Line, Tumor; Cl

2020
Targeting the DNA Damage Response to Overcome Cancer Drug Resistance in Glioblastoma.
    International journal of molecular sciences, 2020, Jul-11, Volume: 21, Issue:14

    Topics: Antineoplastic Agents; Ataxia Telangiectasia Mutated Proteins; Brain Neoplasms; Cell Line, Tumor; Cl

2020
Longer-term (≥ 2 years) survival in patients with glioblastoma in population-based studies pre- and post-2005: a systematic review and meta-analysis.
    Scientific reports, 2020, 07-15, Volume: 10, Issue:1

    Topics: Brain Neoplasms; Cancer Survivors; Chemotherapy, Adjuvant; Disease-Free Survival; Glioblastoma; Huma

2020
Longer-term (≥ 2 years) survival in patients with glioblastoma in population-based studies pre- and post-2005: a systematic review and meta-analysis.
    Scientific reports, 2020, 07-15, Volume: 10, Issue:1

    Topics: Brain Neoplasms; Cancer Survivors; Chemotherapy, Adjuvant; Disease-Free Survival; Glioblastoma; Huma

2020
Longer-term (≥ 2 years) survival in patients with glioblastoma in population-based studies pre- and post-2005: a systematic review and meta-analysis.
    Scientific reports, 2020, 07-15, Volume: 10, Issue:1

    Topics: Brain Neoplasms; Cancer Survivors; Chemotherapy, Adjuvant; Disease-Free Survival; Glioblastoma; Huma

2020
Temozolomide treatment outcomes and immunotherapy efficacy in brain tumor.
    Journal of neuro-oncology, 2021, Volume: 151, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Glioblastoma; Humans; Immunoth

2021
Temozolomide treatment outcomes and immunotherapy efficacy in brain tumor.
    Journal of neuro-oncology, 2021, Volume: 151, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Glioblastoma; Humans; Immunoth

2021
Temozolomide treatment outcomes and immunotherapy efficacy in brain tumor.
    Journal of neuro-oncology, 2021, Volume: 151, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Glioblastoma; Humans; Immunoth

2021
Management of elderly patients with glioblastoma: current status with a focus on the post-operative radiation therapy.
    Annals of palliative medicine, 2020, Volume: 9, Issue:5

    Topics: Aged; Brain Neoplasms; Combined Modality Therapy; Glioblastoma; Humans; Quality of Life; Temozolomid

2020
Management of elderly patients with glioblastoma: current status with a focus on the post-operative radiation therapy.
    Annals of palliative medicine, 2020, Volume: 9, Issue:5

    Topics: Aged; Brain Neoplasms; Combined Modality Therapy; Glioblastoma; Humans; Quality of Life; Temozolomid

2020
Management of elderly patients with glioblastoma: current status with a focus on the post-operative radiation therapy.
    Annals of palliative medicine, 2020, Volume: 9, Issue:5

    Topics: Aged; Brain Neoplasms; Combined Modality Therapy; Glioblastoma; Humans; Quality of Life; Temozolomid

2020
Psychological distress among health care professionals of the three COVID-19 most affected Regions in Cameroon: Prevalence and associated factors.
    Annales medico-psychologiques, 2021, Volume: 179, Issue:2

    Topics: 3' Untranslated Regions; 5'-Nucleotidase; A549 Cells; Accidental Falls; Acetylcholinesterase; Acryli

2021
Psychological distress among health care professionals of the three COVID-19 most affected Regions in Cameroon: Prevalence and associated factors.
    Annales medico-psychologiques, 2021, Volume: 179, Issue:2

    Topics: 3' Untranslated Regions; 5'-Nucleotidase; A549 Cells; Accidental Falls; Acetylcholinesterase; Acryli

2021
Psychological distress among health care professionals of the three COVID-19 most affected Regions in Cameroon: Prevalence and associated factors.
    Annales medico-psychologiques, 2021, Volume: 179, Issue:2

    Topics: 3' Untranslated Regions; 5'-Nucleotidase; A549 Cells; Accidental Falls; Acetylcholinesterase; Acryli

2021
Psychological distress among health care professionals of the three COVID-19 most affected Regions in Cameroon: Prevalence and associated factors.
    Annales medico-psychologiques, 2021, Volume: 179, Issue:2

    Topics: 3' Untranslated Regions; 5'-Nucleotidase; A549 Cells; Accidental Falls; Acetylcholinesterase; Acryli

2021
Psychological distress among health care professionals of the three COVID-19 most affected Regions in Cameroon: Prevalence and associated factors.
    Annales medico-psychologiques, 2021, Volume: 179, Issue:2

    Topics: 3' Untranslated Regions; 5'-Nucleotidase; A549 Cells; Accidental Falls; Acetylcholinesterase; Acryli

2021
Psychological distress among health care professionals of the three COVID-19 most affected Regions in Cameroon: Prevalence and associated factors.
    Annales medico-psychologiques, 2021, Volume: 179, Issue:2

    Topics: 3' Untranslated Regions; 5'-Nucleotidase; A549 Cells; Accidental Falls; Acetylcholinesterase; Acryli

2021
Psychological distress among health care professionals of the three COVID-19 most affected Regions in Cameroon: Prevalence and associated factors.
    Annales medico-psychologiques, 2021, Volume: 179, Issue:2

    Topics: 3' Untranslated Regions; 5'-Nucleotidase; A549 Cells; Accidental Falls; Acetylcholinesterase; Acryli

2021
Psychological distress among health care professionals of the three COVID-19 most affected Regions in Cameroon: Prevalence and associated factors.
    Annales medico-psychologiques, 2021, Volume: 179, Issue:2

    Topics: 3' Untranslated Regions; 5'-Nucleotidase; A549 Cells; Accidental Falls; Acetylcholinesterase; Acryli

2021
Psychological distress among health care professionals of the three COVID-19 most affected Regions in Cameroon: Prevalence and associated factors.
    Annales medico-psychologiques, 2021, Volume: 179, Issue:2

    Topics: 3' Untranslated Regions; 5'-Nucleotidase; A549 Cells; Accidental Falls; Acetylcholinesterase; Acryli

2021
Psychological distress among health care professionals of the three COVID-19 most affected Regions in Cameroon: Prevalence and associated factors.
    Annales medico-psychologiques, 2021, Volume: 179, Issue:2

    Topics: 3' Untranslated Regions; 5'-Nucleotidase; A549 Cells; Accidental Falls; Acetylcholinesterase; Acryli

2021
Psychological distress among health care professionals of the three COVID-19 most affected Regions in Cameroon: Prevalence and associated factors.
    Annales medico-psychologiques, 2021, Volume: 179, Issue:2

    Topics: 3' Untranslated Regions; 5'-Nucleotidase; A549 Cells; Accidental Falls; Acetylcholinesterase; Acryli

2021
Psychological distress among health care professionals of the three COVID-19 most affected Regions in Cameroon: Prevalence and associated factors.
    Annales medico-psychologiques, 2021, Volume: 179, Issue:2

    Topics: 3' Untranslated Regions; 5'-Nucleotidase; A549 Cells; Accidental Falls; Acetylcholinesterase; Acryli

2021
Is chemotherapy alone an option as initial treatment for low-grade oligodendrogliomas?
    Current opinion in neurology, 2020, Volume: 33, Issue:6

    Topics: Antineoplastic Agents; Brain Neoplasms; Humans; Lomustine; Oligodendroglioma; Temozolomide; Treatmen

2020
Is chemotherapy alone an option as initial treatment for low-grade oligodendrogliomas?
    Current opinion in neurology, 2020, Volume: 33, Issue:6

    Topics: Antineoplastic Agents; Brain Neoplasms; Humans; Lomustine; Oligodendroglioma; Temozolomide; Treatmen

2020
Is chemotherapy alone an option as initial treatment for low-grade oligodendrogliomas?
    Current opinion in neurology, 2020, Volume: 33, Issue:6

    Topics: Antineoplastic Agents; Brain Neoplasms; Humans; Lomustine; Oligodendroglioma; Temozolomide; Treatmen

2020
Narrative review of palliative hypofractionated radiotherapy for high grade glioma.
    Annals of palliative medicine, 2021, Volume: 10, Issue:1

    Topics: Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Glioma; Humans; Male; Quality of Life; Tem

2021
Narrative review of palliative hypofractionated radiotherapy for high grade glioma.
    Annals of palliative medicine, 2021, Volume: 10, Issue:1

    Topics: Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Glioma; Humans; Male; Quality of Life; Tem

2021
Narrative review of palliative hypofractionated radiotherapy for high grade glioma.
    Annals of palliative medicine, 2021, Volume: 10, Issue:1

    Topics: Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Glioma; Humans; Male; Quality of Life; Tem

2021
Temozolomide-induced aplastic anaemia: Case report and review of the literature.
    Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners, 2021, Volume: 27, Issue:5

    Topics: Aged; Anemia, Aplastic; Antineoplastic Agents, Alkylating; Brain Neoplasms; Female; Glioblastoma; Gr

2021
Temozolomide-induced aplastic anaemia: Case report and review of the literature.
    Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners, 2021, Volume: 27, Issue:5

    Topics: Aged; Anemia, Aplastic; Antineoplastic Agents, Alkylating; Brain Neoplasms; Female; Glioblastoma; Gr

2021
Temozolomide-induced aplastic anaemia: Case report and review of the literature.
    Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners, 2021, Volume: 27, Issue:5

    Topics: Aged; Anemia, Aplastic; Antineoplastic Agents, Alkylating; Brain Neoplasms; Female; Glioblastoma; Gr

2021
Treatments of gliosarcoma of the brain: a systematic review and meta-analysis.
    Acta neurologica Belgica, 2021, Volume: 121, Issue:6

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Clinical Trials as Topic; Combined Modality Ther

2021
Treatments of gliosarcoma of the brain: a systematic review and meta-analysis.
    Acta neurologica Belgica, 2021, Volume: 121, Issue:6

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Clinical Trials as Topic; Combined Modality Ther

2021
Treatments of gliosarcoma of the brain: a systematic review and meta-analysis.
    Acta neurologica Belgica, 2021, Volume: 121, Issue:6

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Clinical Trials as Topic; Combined Modality Ther

2021
Update on the management of elderly patients with glioblastoma: a narrative review.
    Annals of palliative medicine, 2021, Volume: 10, Issue:1

    Topics: Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Glioblastoma; Humans; Quality of Life; Ran

2021
Update on the management of elderly patients with glioblastoma: a narrative review.
    Annals of palliative medicine, 2021, Volume: 10, Issue:1

    Topics: Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Glioblastoma; Humans; Quality of Life; Ran

2021
Update on the management of elderly patients with glioblastoma: a narrative review.
    Annals of palliative medicine, 2021, Volume: 10, Issue:1

    Topics: Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Glioblastoma; Humans; Quality of Life; Ran

2021
Radiation-Associated Glioblastoma after Prophylactic Cranial Irradiation in a Patient of ALL: Review of Literature and Report of a Rare Case.
    Pediatric neurosurgery, 2020, Volume: 55, Issue:6

    Topics: Brain Neoplasms; Child, Preschool; Cranial Irradiation; Glioblastoma; Humans; Male; Neoplasm Recurre

2020
Radiation-Associated Glioblastoma after Prophylactic Cranial Irradiation in a Patient of ALL: Review of Literature and Report of a Rare Case.
    Pediatric neurosurgery, 2020, Volume: 55, Issue:6

    Topics: Brain Neoplasms; Child, Preschool; Cranial Irradiation; Glioblastoma; Humans; Male; Neoplasm Recurre

2020
Radiation-Associated Glioblastoma after Prophylactic Cranial Irradiation in a Patient of ALL: Review of Literature and Report of a Rare Case.
    Pediatric neurosurgery, 2020, Volume: 55, Issue:6

    Topics: Brain Neoplasms; Child, Preschool; Cranial Irradiation; Glioblastoma; Humans; Male; Neoplasm Recurre

2020
Updated Insights on EGFR Signaling Pathways in Glioma.
    International journal of molecular sciences, 2021, Jan-08, Volume: 22, Issue:2

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; ErbB Receptors; Gene

2021
Updated Insights on EGFR Signaling Pathways in Glioma.
    International journal of molecular sciences, 2021, Jan-08, Volume: 22, Issue:2

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; ErbB Receptors; Gene

2021
Updated Insights on EGFR Signaling Pathways in Glioma.
    International journal of molecular sciences, 2021, Jan-08, Volume: 22, Issue:2

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; ErbB Receptors; Gene

2021
The efficacy of hypofractionated radiotherapy (HFRT) with concurrent and adjuvant temozolomide in newly diagnosed glioblastoma: A meta-analysis.
    Cancer radiotherapie : journal de la Societe francaise de radiotherapie oncologique, 2021, Volume: 25, Issue:2

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Chemotherapy, Adjuvant; Gliob

2021
The efficacy of hypofractionated radiotherapy (HFRT) with concurrent and adjuvant temozolomide in newly diagnosed glioblastoma: A meta-analysis.
    Cancer radiotherapie : journal de la Societe francaise de radiotherapie oncologique, 2021, Volume: 25, Issue:2

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Chemotherapy, Adjuvant; Gliob

2021
The efficacy of hypofractionated radiotherapy (HFRT) with concurrent and adjuvant temozolomide in newly diagnosed glioblastoma: A meta-analysis.
    Cancer radiotherapie : journal de la Societe francaise de radiotherapie oncologique, 2021, Volume: 25, Issue:2

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Chemotherapy, Adjuvant; Gliob

2021
Natural substances to potentiate canonical glioblastoma chemotherapy.
    Journal of chemotherapy (Florence, Italy), 2021, Volume: 33, Issue:5

    Topics: Anthraquinones; Biological Products; Brain Neoplasms; Catechols; Cell Cycle; Dose-Response Relations

2021
Natural substances to potentiate canonical glioblastoma chemotherapy.
    Journal of chemotherapy (Florence, Italy), 2021, Volume: 33, Issue:5

    Topics: Anthraquinones; Biological Products; Brain Neoplasms; Catechols; Cell Cycle; Dose-Response Relations

2021
Natural substances to potentiate canonical glioblastoma chemotherapy.
    Journal of chemotherapy (Florence, Italy), 2021, Volume: 33, Issue:5

    Topics: Anthraquinones; Biological Products; Brain Neoplasms; Catechols; Cell Cycle; Dose-Response Relations

2021
Prolonged survival following everolimus combined with temozolomide for metastatic malignant melanoma with FBXW7 mutation: a case report and literature review.
    Annals of palliative medicine, 2021, Volume: 10, Issue:7

    Topics: Adult; Brain Neoplasms; Dacarbazine; Everolimus; F-Box-WD Repeat-Containing Protein 7; Humans; Male;

2021
Prolonged survival following everolimus combined with temozolomide for metastatic malignant melanoma with FBXW7 mutation: a case report and literature review.
    Annals of palliative medicine, 2021, Volume: 10, Issue:7

    Topics: Adult; Brain Neoplasms; Dacarbazine; Everolimus; F-Box-WD Repeat-Containing Protein 7; Humans; Male;

2021
Prolonged survival following everolimus combined with temozolomide for metastatic malignant melanoma with FBXW7 mutation: a case report and literature review.
    Annals of palliative medicine, 2021, Volume: 10, Issue:7

    Topics: Adult; Brain Neoplasms; Dacarbazine; Everolimus; F-Box-WD Repeat-Containing Protein 7; Humans; Male;

2021
Prognostic value of test(s) for O6-methylguanine-DNA methyltransferase (MGMT) promoter methylation for predicting overall survival in people with glioblastoma treated with temozolomide.
    The Cochrane database of systematic reviews, 2021, 03-12, Volume: 3

    Topics: Adult; Antineoplastic Agents, Alkylating; Bias; Brain Neoplasms; Cohort Studies; CpG Islands; DNA Me

2021
Prognostic value of test(s) for O6-methylguanine-DNA methyltransferase (MGMT) promoter methylation for predicting overall survival in people with glioblastoma treated with temozolomide.
    The Cochrane database of systematic reviews, 2021, 03-12, Volume: 3

    Topics: Adult; Antineoplastic Agents, Alkylating; Bias; Brain Neoplasms; Cohort Studies; CpG Islands; DNA Me

2021
Prognostic value of test(s) for O6-methylguanine-DNA methyltransferase (MGMT) promoter methylation for predicting overall survival in people with glioblastoma treated with temozolomide.
    The Cochrane database of systematic reviews, 2021, 03-12, Volume: 3

    Topics: Adult; Antineoplastic Agents, Alkylating; Bias; Brain Neoplasms; Cohort Studies; CpG Islands; DNA Me

2021
Novel Radiation Approaches.
    Neurosurgery clinics of North America, 2021, Volume: 32, Issue:2

    Topics: Brain Neoplasms; Glioblastoma; Humans; Temozolomide

2021
Novel Radiation Approaches.
    Neurosurgery clinics of North America, 2021, Volume: 32, Issue:2

    Topics: Brain Neoplasms; Glioblastoma; Humans; Temozolomide

2021
Novel Radiation Approaches.
    Neurosurgery clinics of North America, 2021, Volume: 32, Issue:2

    Topics: Brain Neoplasms; Glioblastoma; Humans; Temozolomide

2021
Long Non-Coding RNAs in Multidrug Resistance of Glioblastoma.
    Genes, 2021, 03-23, Volume: 12, Issue:3

    Topics: Antineoplastic Agents; Brain Neoplasms; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Gene E

2021
Long Non-Coding RNAs in Multidrug Resistance of Glioblastoma.
    Genes, 2021, 03-23, Volume: 12, Issue:3

    Topics: Antineoplastic Agents; Brain Neoplasms; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Gene E

2021
Long Non-Coding RNAs in Multidrug Resistance of Glioblastoma.
    Genes, 2021, 03-23, Volume: 12, Issue:3

    Topics: Antineoplastic Agents; Brain Neoplasms; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Gene E

2021
Potential new targets and drugs related to histone modifications in glioma treatment.
    Bioorganic chemistry, 2021, Volume: 112

    Topics: Antineoplastic Agents; Brain Neoplasms; DNA Damage; Drug Resistance, Neoplasm; Glioma; Histones; Hum

2021
Potential new targets and drugs related to histone modifications in glioma treatment.
    Bioorganic chemistry, 2021, Volume: 112

    Topics: Antineoplastic Agents; Brain Neoplasms; DNA Damage; Drug Resistance, Neoplasm; Glioma; Histones; Hum

2021
Potential new targets and drugs related to histone modifications in glioma treatment.
    Bioorganic chemistry, 2021, Volume: 112

    Topics: Antineoplastic Agents; Brain Neoplasms; DNA Damage; Drug Resistance, Neoplasm; Glioma; Histones; Hum

2021
Dose Escalated Radiation Therapy for Glioblastoma Multiforme: An International Systematic Review and Meta-Analysis of 22 Prospective Trials.
    International journal of radiation oncology, biology, physics, 2021, 10-01, Volume: 111, Issue:2

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Brain Neoplasms; Child; DNA Modification Methylases; DNA

2021
Dose Escalated Radiation Therapy for Glioblastoma Multiforme: An International Systematic Review and Meta-Analysis of 22 Prospective Trials.
    International journal of radiation oncology, biology, physics, 2021, 10-01, Volume: 111, Issue:2

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Brain Neoplasms; Child; DNA Modification Methylases; DNA

2021
Dose Escalated Radiation Therapy for Glioblastoma Multiforme: An International Systematic Review and Meta-Analysis of 22 Prospective Trials.
    International journal of radiation oncology, biology, physics, 2021, 10-01, Volume: 111, Issue:2

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Brain Neoplasms; Child; DNA Modification Methylases; DNA

2021
DDRugging glioblastoma: understanding and targeting the DNA damage response to improve future therapies.
    Molecular oncology, 2022, Volume: 16, Issue:1

    Topics: Adult; Brain Neoplasms; Clinical Trials, Phase III as Topic; Combined Modality Therapy; DNA Damage;

2022
DDRugging glioblastoma: understanding and targeting the DNA damage response to improve future therapies.
    Molecular oncology, 2022, Volume: 16, Issue:1

    Topics: Adult; Brain Neoplasms; Clinical Trials, Phase III as Topic; Combined Modality Therapy; DNA Damage;

2022
DDRugging glioblastoma: understanding and targeting the DNA damage response to improve future therapies.
    Molecular oncology, 2022, Volume: 16, Issue:1

    Topics: Adult; Brain Neoplasms; Clinical Trials, Phase III as Topic; Combined Modality Therapy; DNA Damage;

2022
DNA damage repair in glioblastoma: current perspectives on its role in tumour progression, treatment resistance and PIKKing potential therapeutic targets.
    Cellular oncology (Dordrecht), 2021, Volume: 44, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Cycle Checkpoints; DNA Damage; DNA Repair;

2021
DNA damage repair in glioblastoma: current perspectives on its role in tumour progression, treatment resistance and PIKKing potential therapeutic targets.
    Cellular oncology (Dordrecht), 2021, Volume: 44, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Cycle Checkpoints; DNA Damage; DNA Repair;

2021
DNA damage repair in glioblastoma: current perspectives on its role in tumour progression, treatment resistance and PIKKing potential therapeutic targets.
    Cellular oncology (Dordrecht), 2021, Volume: 44, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Cycle Checkpoints; DNA Damage; DNA Repair;

2021
From Laboratory Studies to Clinical Trials: Temozolomide Use in IDH-Mutant Gliomas.
    Cells, 2021, 05-17, Volume: 10, Issue:5

    Topics: Animals; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Biomarke

2021
From Laboratory Studies to Clinical Trials: Temozolomide Use in IDH-Mutant Gliomas.
    Cells, 2021, 05-17, Volume: 10, Issue:5

    Topics: Animals; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Biomarke

2021
From Laboratory Studies to Clinical Trials: Temozolomide Use in IDH-Mutant Gliomas.
    Cells, 2021, 05-17, Volume: 10, Issue:5

    Topics: Animals; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Biomarke

2021
Oncogenesis, Microenvironment Modulation and Clinical Potentiality of FAP in Glioblastoma: Lessons Learned from Other Solid Tumors.
    Cells, 2021, 05-10, Volume: 10, Issue:5

    Topics: Animals; Biomarkers; Biomarkers, Tumor; Brain Neoplasms; Cancer-Associated Fibroblasts; Carcinogenes

2021
Oncogenesis, Microenvironment Modulation and Clinical Potentiality of FAP in Glioblastoma: Lessons Learned from Other Solid Tumors.
    Cells, 2021, 05-10, Volume: 10, Issue:5

    Topics: Animals; Biomarkers; Biomarkers, Tumor; Brain Neoplasms; Cancer-Associated Fibroblasts; Carcinogenes

2021
Oncogenesis, Microenvironment Modulation and Clinical Potentiality of FAP in Glioblastoma: Lessons Learned from Other Solid Tumors.
    Cells, 2021, 05-10, Volume: 10, Issue:5

    Topics: Animals; Biomarkers; Biomarkers, Tumor; Brain Neoplasms; Cancer-Associated Fibroblasts; Carcinogenes

2021
Outcomes in Elderly Patients with Glioblastoma Multiforme Treated with Short-Course Radiation Alone Compared to Short-Course Radiation and Concurrent and Adjuvant Temozolomide Based on Performance Status and Extent of Resection.
    Current oncology (Toronto, Ont.), 2021, 06-26, Volume: 28, Issue:4

    Topics: Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Glioblastoma; Humans; Quality

2021
Outcomes in Elderly Patients with Glioblastoma Multiforme Treated with Short-Course Radiation Alone Compared to Short-Course Radiation and Concurrent and Adjuvant Temozolomide Based on Performance Status and Extent of Resection.
    Current oncology (Toronto, Ont.), 2021, 06-26, Volume: 28, Issue:4

    Topics: Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Glioblastoma; Humans; Quality

2021
Outcomes in Elderly Patients with Glioblastoma Multiforme Treated with Short-Course Radiation Alone Compared to Short-Course Radiation and Concurrent and Adjuvant Temozolomide Based on Performance Status and Extent of Resection.
    Current oncology (Toronto, Ont.), 2021, 06-26, Volume: 28, Issue:4

    Topics: Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Glioblastoma; Humans; Quality

2021
Progress and prospect in tumor treating fields treatment of glioblastoma.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2021, Volume: 141

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Combined Modality Th

2021
Progress and prospect in tumor treating fields treatment of glioblastoma.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2021, Volume: 141

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Combined Modality Th

2021
Progress and prospect in tumor treating fields treatment of glioblastoma.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2021, Volume: 141

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Combined Modality Th

2021
Temozolomide nano enabled medicine: promises made by the nanocarriers in glioblastoma therapy.
    Journal of controlled release : official journal of the Controlled Release Society, 2021, 08-10, Volume: 336

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; Gli

2021
Temozolomide nano enabled medicine: promises made by the nanocarriers in glioblastoma therapy.
    Journal of controlled release : official journal of the Controlled Release Society, 2021, 08-10, Volume: 336

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; Gli

2021
Temozolomide nano enabled medicine: promises made by the nanocarriers in glioblastoma therapy.
    Journal of controlled release : official journal of the Controlled Release Society, 2021, 08-10, Volume: 336

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; Gli

2021
Antioxidant responses related to temozolomide resistance in glioblastoma.
    Neurochemistry international, 2021, Volume: 149

    Topics: Animals; Antineoplastic Agents, Alkylating; Antioxidants; Brain Neoplasms; Drug Resistance, Neoplasm

2021
Antioxidant responses related to temozolomide resistance in glioblastoma.
    Neurochemistry international, 2021, Volume: 149

    Topics: Animals; Antineoplastic Agents, Alkylating; Antioxidants; Brain Neoplasms; Drug Resistance, Neoplasm

2021
Antioxidant responses related to temozolomide resistance in glioblastoma.
    Neurochemistry international, 2021, Volume: 149

    Topics: Animals; Antineoplastic Agents, Alkylating; Antioxidants; Brain Neoplasms; Drug Resistance, Neoplasm

2021
    Middle East Fertility Society journal, 2021, Volume: 26, Issue:1

    Topics: alpha7 Nicotinic Acetylcholine Receptor; Animals; Basigin; beta-Transducin Repeat-Containing Protein

2021
    Middle East Fertility Society journal, 2021, Volume: 26, Issue:1

    Topics: alpha7 Nicotinic Acetylcholine Receptor; Animals; Basigin; beta-Transducin Repeat-Containing Protein

2021
    Middle East Fertility Society journal, 2021, Volume: 26, Issue:1

    Topics: alpha7 Nicotinic Acetylcholine Receptor; Animals; Basigin; beta-Transducin Repeat-Containing Protein

2021
An overview of current results with the vincristine-irinotecan-temozolomide combination with or without bevacizumab in pediatric, adolescence and adult solid tumors.
    Critical reviews in oncology/hematology, 2021, Volume: 166

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Brain Neoplasms; Cam

2021
An overview of current results with the vincristine-irinotecan-temozolomide combination with or without bevacizumab in pediatric, adolescence and adult solid tumors.
    Critical reviews in oncology/hematology, 2021, Volume: 166

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Brain Neoplasms; Cam

2021
An overview of current results with the vincristine-irinotecan-temozolomide combination with or without bevacizumab in pediatric, adolescence and adult solid tumors.
    Critical reviews in oncology/hematology, 2021, Volume: 166

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Brain Neoplasms; Cam

2021
MGMT gene variants, temozolomide myelotoxicity and glioma risk. A concise literature survey including an illustrative case.
    Journal of chemotherapy (Florence, Italy), 2017, Volume: 29, Issue:4

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; DNA Modification Methylases; DNA Re

2017
MGMT gene variants, temozolomide myelotoxicity and glioma risk. A concise literature survey including an illustrative case.
    Journal of chemotherapy (Florence, Italy), 2017, Volume: 29, Issue:4

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; DNA Modification Methylases; DNA Re

2017
MGMT gene variants, temozolomide myelotoxicity and glioma risk. A concise literature survey including an illustrative case.
    Journal of chemotherapy (Florence, Italy), 2017, Volume: 29, Issue:4

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; DNA Modification Methylases; DNA Re

2017
The interventional effect of new drugs combined with the Stupp protocol on glioblastoma: A network meta-analysis.
    Clinical neurology and neurosurgery, 2017, Volume: 159

    Topics: Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms;

2017
The interventional effect of new drugs combined with the Stupp protocol on glioblastoma: A network meta-analysis.
    Clinical neurology and neurosurgery, 2017, Volume: 159

    Topics: Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms;

2017
The interventional effect of new drugs combined with the Stupp protocol on glioblastoma: A network meta-analysis.
    Clinical neurology and neurosurgery, 2017, Volume: 159

    Topics: Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms;

2017
Managing Glioblastoma in the Elderly Patient: New Opportunities.
    Oncology (Williston Park, N.Y.), 2017, 06-15, Volume: 31, Issue:6

    Topics: Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant; Dacarbazine; Disea

2017
Managing Glioblastoma in the Elderly Patient: New Opportunities.
    Oncology (Williston Park, N.Y.), 2017, 06-15, Volume: 31, Issue:6

    Topics: Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant; Dacarbazine; Disea

2017
Managing Glioblastoma in the Elderly Patient: New Opportunities.
    Oncology (Williston Park, N.Y.), 2017, 06-15, Volume: 31, Issue:6

    Topics: Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant; Dacarbazine; Disea

2017
Complete durable response of a pediatric anaplastic oligodendroglioma to temozolomide alone: Case report and review of literature.
    Pediatric blood & cancer, 2017, Volume: 64, Issue:12

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Child; Dacarbazine; Humans; Isocitrate Dehydroge

2017
Complete durable response of a pediatric anaplastic oligodendroglioma to temozolomide alone: Case report and review of literature.
    Pediatric blood & cancer, 2017, Volume: 64, Issue:12

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Child; Dacarbazine; Humans; Isocitrate Dehydroge

2017
Complete durable response of a pediatric anaplastic oligodendroglioma to temozolomide alone: Case report and review of literature.
    Pediatric blood & cancer, 2017, Volume: 64, Issue:12

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Child; Dacarbazine; Humans; Isocitrate Dehydroge

2017
Combined treatment for non-small cell lung cancer and breast cancer patients with brain metastases with whole brain radiotherapy and temozolomide: a systematic review and meta-analysis.
    Journal of neuro-oncology, 2017, Volume: 135, Issue:2

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Breast Neoplasms; Carcinoma, Non-Small-Cell Lung

2017
Combined treatment for non-small cell lung cancer and breast cancer patients with brain metastases with whole brain radiotherapy and temozolomide: a systematic review and meta-analysis.
    Journal of neuro-oncology, 2017, Volume: 135, Issue:2

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Breast Neoplasms; Carcinoma, Non-Small-Cell Lung

2017
Combined treatment for non-small cell lung cancer and breast cancer patients with brain metastases with whole brain radiotherapy and temozolomide: a systematic review and meta-analysis.
    Journal of neuro-oncology, 2017, Volume: 135, Issue:2

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Breast Neoplasms; Carcinoma, Non-Small-Cell Lung

2017
Procarbazine, lomustine and vincristine for recurrent high-grade glioma.
    The Cochrane database of systematic reviews, 2017, 07-26, Volume: 7

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Cytarabine; Dacarbazine; Dis

2017
Procarbazine, lomustine and vincristine for recurrent high-grade glioma.
    The Cochrane database of systematic reviews, 2017, 07-26, Volume: 7

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Cytarabine; Dacarbazine; Dis

2017
Procarbazine, lomustine and vincristine for recurrent high-grade glioma.
    The Cochrane database of systematic reviews, 2017, 07-26, Volume: 7

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Cytarabine; Dacarbazine; Dis

2017
The Evolving Role of Tumor Treating Fields in Managing Glioblastoma: Guide for Oncologists.
    American journal of clinical oncology, 2018, Volume: 41, Issue:2

    Topics: Animals; Brain Neoplasms; Cause of Death; Chemoradiotherapy; Combined Modality Therapy; Disease Mana

2018
The Evolving Role of Tumor Treating Fields in Managing Glioblastoma: Guide for Oncologists.
    American journal of clinical oncology, 2018, Volume: 41, Issue:2

    Topics: Animals; Brain Neoplasms; Cause of Death; Chemoradiotherapy; Combined Modality Therapy; Disease Mana

2018
The Evolving Role of Tumor Treating Fields in Managing Glioblastoma: Guide for Oncologists.
    American journal of clinical oncology, 2018, Volume: 41, Issue:2

    Topics: Animals; Brain Neoplasms; Cause of Death; Chemoradiotherapy; Combined Modality Therapy; Disease Mana

2018
Glioblastoma in the elderly: initial management.
    Chinese clinical oncology, 2017, Volume: 6, Issue:4

    Topics: Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant; Clinical Trials, P

2017
Glioblastoma in the elderly: initial management.
    Chinese clinical oncology, 2017, Volume: 6, Issue:4

    Topics: Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant; Clinical Trials, P

2017
Glioblastoma in the elderly: initial management.
    Chinese clinical oncology, 2017, Volume: 6, Issue:4

    Topics: Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant; Clinical Trials, P

2017
Tumor treating fields: a novel and effective therapy for glioblastoma: mechanism, efficacy, safety and future perspectives.
    Chinese clinical oncology, 2017, Volume: 6, Issue:4

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Clinical Trials, Phase III as Topic; Combined Mo

2017
Tumor treating fields: a novel and effective therapy for glioblastoma: mechanism, efficacy, safety and future perspectives.
    Chinese clinical oncology, 2017, Volume: 6, Issue:4

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Clinical Trials, Phase III as Topic; Combined Mo

2017
Tumor treating fields: a novel and effective therapy for glioblastoma: mechanism, efficacy, safety and future perspectives.
    Chinese clinical oncology, 2017, Volume: 6, Issue:4

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Clinical Trials, Phase III as Topic; Combined Mo

2017
Regression of Recurrent High-Grade Glioma with Temozolomide, Dexamethasone, and Levetiracetam: Case Report and Review of the Literature.
    World neurosurgery, 2017, Volume: 108

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Chemoradiotherapy; Corpus Ca

2017
Regression of Recurrent High-Grade Glioma with Temozolomide, Dexamethasone, and Levetiracetam: Case Report and Review of the Literature.
    World neurosurgery, 2017, Volume: 108

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Chemoradiotherapy; Corpus Ca

2017
Regression of Recurrent High-Grade Glioma with Temozolomide, Dexamethasone, and Levetiracetam: Case Report and Review of the Literature.
    World neurosurgery, 2017, Volume: 108

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Chemoradiotherapy; Corpus Ca

2017
Glioblastoma in elderly patients: solid conclusions built on shifting sand?
    Neuro-oncology, 2018, 01-22, Volume: 20, Issue:2

    Topics: Aging; Antineoplastic Agents, Alkylating; Brain Neoplasms; Glioblastoma; Humans; Temozolomide; Treat

2018
Glioblastoma in elderly patients: solid conclusions built on shifting sand?
    Neuro-oncology, 2018, 01-22, Volume: 20, Issue:2

    Topics: Aging; Antineoplastic Agents, Alkylating; Brain Neoplasms; Glioblastoma; Humans; Temozolomide; Treat

2018
Glioblastoma in elderly patients: solid conclusions built on shifting sand?
    Neuro-oncology, 2018, 01-22, Volume: 20, Issue:2

    Topics: Aging; Antineoplastic Agents, Alkylating; Brain Neoplasms; Glioblastoma; Humans; Temozolomide; Treat

2018
Treatment of Glioblastoma.
    Journal of oncology practice, 2017, Volume: 13, Issue:10

    Topics: Aftercare; Age Factors; Angiogenesis Inhibitors; Antineoplastic Agents, Alkylating; Bevacizumab; Bra

2017
Treatment of Glioblastoma.
    Journal of oncology practice, 2017, Volume: 13, Issue:10

    Topics: Aftercare; Age Factors; Angiogenesis Inhibitors; Antineoplastic Agents, Alkylating; Bevacizumab; Bra

2017
Treatment of Glioblastoma.
    Journal of oncology practice, 2017, Volume: 13, Issue:10

    Topics: Aftercare; Age Factors; Angiogenesis Inhibitors; Antineoplastic Agents, Alkylating; Bevacizumab; Bra

2017
Glioblastoma and chemoresistance to alkylating agents: Involvement of apoptosis, autophagy, and unfolded protein response.
    Pharmacology & therapeutics, 2018, Volume: 184

    Topics: Animals; Apoptosis; Autophagy; Brain Neoplasms; Drug Resistance, Neoplasm; Glioblastoma; Humans; Mod

2018
Glioblastoma and chemoresistance to alkylating agents: Involvement of apoptosis, autophagy, and unfolded protein response.
    Pharmacology & therapeutics, 2018, Volume: 184

    Topics: Animals; Apoptosis; Autophagy; Brain Neoplasms; Drug Resistance, Neoplasm; Glioblastoma; Humans; Mod

2018
Glioblastoma and chemoresistance to alkylating agents: Involvement of apoptosis, autophagy, and unfolded protein response.
    Pharmacology & therapeutics, 2018, Volume: 184

    Topics: Animals; Apoptosis; Autophagy; Brain Neoplasms; Drug Resistance, Neoplasm; Glioblastoma; Humans; Mod

2018
Carmustine wafer implantation for high-grade gliomas: Evidence-based safety efficacy and practical recommendations from the Neuro-oncology Club of the French Society of Neurosurgery.
    Neuro-Chirurgie, 2017, Volume: 63, Issue:6

    Topics: Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms;

2017
Carmustine wafer implantation for high-grade gliomas: Evidence-based safety efficacy and practical recommendations from the Neuro-oncology Club of the French Society of Neurosurgery.
    Neuro-Chirurgie, 2017, Volume: 63, Issue:6

    Topics: Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms;

2017
Carmustine wafer implantation for high-grade gliomas: Evidence-based safety efficacy and practical recommendations from the Neuro-oncology Club of the French Society of Neurosurgery.
    Neuro-Chirurgie, 2017, Volume: 63, Issue:6

    Topics: Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms;

2017
Fractionated Radiotherapy of Intracranial Gliomas.
    Progress in neurological surgery, 2018, Volume: 31

    Topics: Adult; Brain Neoplasms; Dacarbazine; Dose Fractionation, Radiation; Glioblastoma; Glioma; Humans; Ma

2018
Fractionated Radiotherapy of Intracranial Gliomas.
    Progress in neurological surgery, 2018, Volume: 31

    Topics: Adult; Brain Neoplasms; Dacarbazine; Dose Fractionation, Radiation; Glioblastoma; Glioma; Humans; Ma

2018
Fractionated Radiotherapy of Intracranial Gliomas.
    Progress in neurological surgery, 2018, Volume: 31

    Topics: Adult; Brain Neoplasms; Dacarbazine; Dose Fractionation, Radiation; Glioblastoma; Glioma; Humans; Ma

2018
Chemotherapy of High-Grade Astrocytomas in Adults.
    Progress in neurological surgery, 2018, Volume: 31

    Topics: Adult; Astrocytoma; Brain Neoplasms; Dacarbazine; Glioblastoma; Glioma; Humans; Neoplasm Grading; Te

2018
Chemotherapy of High-Grade Astrocytomas in Adults.
    Progress in neurological surgery, 2018, Volume: 31

    Topics: Adult; Astrocytoma; Brain Neoplasms; Dacarbazine; Glioblastoma; Glioma; Humans; Neoplasm Grading; Te

2018
Chemotherapy of High-Grade Astrocytomas in Adults.
    Progress in neurological surgery, 2018, Volume: 31

    Topics: Adult; Astrocytoma; Brain Neoplasms; Dacarbazine; Glioblastoma; Glioma; Humans; Neoplasm Grading; Te

2018
Temozolomide-associated hypermutation in gliomas.
    Neuro-oncology, 2018, 09-03, Volume: 20, Issue:10

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Disease Progression; DNA Methylation; DNA Repair

2018
Temozolomide-associated hypermutation in gliomas.
    Neuro-oncology, 2018, 09-03, Volume: 20, Issue:10

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Disease Progression; DNA Methylation; DNA Repair

2018
Temozolomide-associated hypermutation in gliomas.
    Neuro-oncology, 2018, 09-03, Volume: 20, Issue:10

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Disease Progression; DNA Methylation; DNA Repair

2018
Meta-analysis of whole-brain radiotherapy plus temozolomide compared with whole-brain radiotherapy for the treatment of brain metastases from non-small-cell lung cancer.
    Cancer medicine, 2018, Volume: 7, Issue:4

    Topics: Brain Neoplasms; Carcinoma, Non-Small-Cell Lung; Clinical Trials as Topic; Combined Modality Therapy

2018
Meta-analysis of whole-brain radiotherapy plus temozolomide compared with whole-brain radiotherapy for the treatment of brain metastases from non-small-cell lung cancer.
    Cancer medicine, 2018, Volume: 7, Issue:4

    Topics: Brain Neoplasms; Carcinoma, Non-Small-Cell Lung; Clinical Trials as Topic; Combined Modality Therapy

2018
Meta-analysis of whole-brain radiotherapy plus temozolomide compared with whole-brain radiotherapy for the treatment of brain metastases from non-small-cell lung cancer.
    Cancer medicine, 2018, Volume: 7, Issue:4

    Topics: Brain Neoplasms; Carcinoma, Non-Small-Cell Lung; Clinical Trials as Topic; Combined Modality Therapy

2018
An Interplay between Senescence, Apoptosis and Autophagy in Glioblastoma Multiforme-Role in Pathogenesis and Therapeutic Perspective.
    International journal of molecular sciences, 2018, Mar-17, Volume: 19, Issue:3

    Topics: Animals; Antineoplastic Agents, Alkylating; Apoptosis; Autophagy; Brain Neoplasms; Cellular Senescen

2018
An Interplay between Senescence, Apoptosis and Autophagy in Glioblastoma Multiforme-Role in Pathogenesis and Therapeutic Perspective.
    International journal of molecular sciences, 2018, Mar-17, Volume: 19, Issue:3

    Topics: Animals; Antineoplastic Agents, Alkylating; Apoptosis; Autophagy; Brain Neoplasms; Cellular Senescen

2018
An Interplay between Senescence, Apoptosis and Autophagy in Glioblastoma Multiforme-Role in Pathogenesis and Therapeutic Perspective.
    International journal of molecular sciences, 2018, Mar-17, Volume: 19, Issue:3

    Topics: Animals; Antineoplastic Agents, Alkylating; Apoptosis; Autophagy; Brain Neoplasms; Cellular Senescen

2018
Opposite Interplay Between the Canonical WNT/β-Catenin Pathway and PPAR Gamma: A Potential Therapeutic Target in Gliomas.
    Neuroscience bulletin, 2018, Volume: 34, Issue:3

    Topics: Animals; Brain Neoplasms; Dacarbazine; Down-Regulation; Glioma; Humans; PPAR gamma; Temozolomide; Wn

2018
Opposite Interplay Between the Canonical WNT/β-Catenin Pathway and PPAR Gamma: A Potential Therapeutic Target in Gliomas.
    Neuroscience bulletin, 2018, Volume: 34, Issue:3

    Topics: Animals; Brain Neoplasms; Dacarbazine; Down-Regulation; Glioma; Humans; PPAR gamma; Temozolomide; Wn

2018
Opposite Interplay Between the Canonical WNT/β-Catenin Pathway and PPAR Gamma: A Potential Therapeutic Target in Gliomas.
    Neuroscience bulletin, 2018, Volume: 34, Issue:3

    Topics: Animals; Brain Neoplasms; Dacarbazine; Down-Regulation; Glioma; Humans; PPAR gamma; Temozolomide; Wn

2018
Repurposing drugs for glioblastoma: From bench to bedside.
    Cancer letters, 2018, 08-01, Volume: 428

    Topics: Antineoplastic Agents; Brain Neoplasms; Clinical Trials as Topic; Drug Repositioning; Drug Resistanc

2018
Repurposing drugs for glioblastoma: From bench to bedside.
    Cancer letters, 2018, 08-01, Volume: 428

    Topics: Antineoplastic Agents; Brain Neoplasms; Clinical Trials as Topic; Drug Repositioning; Drug Resistanc

2018
Repurposing drugs for glioblastoma: From bench to bedside.
    Cancer letters, 2018, 08-01, Volume: 428

    Topics: Antineoplastic Agents; Brain Neoplasms; Clinical Trials as Topic; Drug Repositioning; Drug Resistanc

2018
Temozolomide for immunomodulation in the treatment of glioblastoma.
    Neuro-oncology, 2018, 11-12, Volume: 20, Issue:12

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Glioblastoma; Humans; Immunomodulation; Prognosi

2018
Temozolomide for immunomodulation in the treatment of glioblastoma.
    Neuro-oncology, 2018, 11-12, Volume: 20, Issue:12

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Glioblastoma; Humans; Immunomodulation; Prognosi

2018
Temozolomide for immunomodulation in the treatment of glioblastoma.
    Neuro-oncology, 2018, 11-12, Volume: 20, Issue:12

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Glioblastoma; Humans; Immunomodulation; Prognosi

2018
MGMT Expression Contributes to Temozolomide Resistance in H3K27M-Mutant Diffuse Midline Gliomas and MGMT Silencing to Temozolomide Sensitivity in IDH-Mutant Gliomas.
    Neurologia medico-chirurgica, 2018, Jul-15, Volume: 58, Issue:7

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; DNA Modification Methylases; DNA Repair Enzymes;

2018
MGMT Expression Contributes to Temozolomide Resistance in H3K27M-Mutant Diffuse Midline Gliomas and MGMT Silencing to Temozolomide Sensitivity in IDH-Mutant Gliomas.
    Neurologia medico-chirurgica, 2018, Jul-15, Volume: 58, Issue:7

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; DNA Modification Methylases; DNA Repair Enzymes;

2018
MGMT Expression Contributes to Temozolomide Resistance in H3K27M-Mutant Diffuse Midline Gliomas and MGMT Silencing to Temozolomide Sensitivity in IDH-Mutant Gliomas.
    Neurologia medico-chirurgica, 2018, Jul-15, Volume: 58, Issue:7

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; DNA Modification Methylases; DNA Repair Enzymes;

2018
Involvement of Intracellular Cholesterol in Temozolomide-Induced Glioblastoma Cell Death.
    Neurologia medico-chirurgica, 2018, Jul-15, Volume: 58, Issue:7

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Death; Cholesterol; Drug Resistance, Neopla

2018
Involvement of Intracellular Cholesterol in Temozolomide-Induced Glioblastoma Cell Death.
    Neurologia medico-chirurgica, 2018, Jul-15, Volume: 58, Issue:7

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Death; Cholesterol; Drug Resistance, Neopla

2018
Involvement of Intracellular Cholesterol in Temozolomide-Induced Glioblastoma Cell Death.
    Neurologia medico-chirurgica, 2018, Jul-15, Volume: 58, Issue:7

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Death; Cholesterol; Drug Resistance, Neopla

2018
Alternating Electric Fields Therapy for Malignant Gliomas: From Bench Observation to Clinical Reality.
    Progress in neurological surgery, 2018, Volume: 32

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Electric

2018
Alternating Electric Fields Therapy for Malignant Gliomas: From Bench Observation to Clinical Reality.
    Progress in neurological surgery, 2018, Volume: 32

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Electric

2018
Alternating Electric Fields Therapy for Malignant Gliomas: From Bench Observation to Clinical Reality.
    Progress in neurological surgery, 2018, Volume: 32

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Electric

2018
Treatment of Glioblastoma in the Elderly.
    Drugs & aging, 2018, Volume: 35, Issue:8

    Topics: Aged; Brain Neoplasms; Chemotherapy, Adjuvant; Dacarbazine; Glioblastoma; Humans; O(6)-Methylguanine

2018
Treatment of Glioblastoma in the Elderly.
    Drugs & aging, 2018, Volume: 35, Issue:8

    Topics: Aged; Brain Neoplasms; Chemotherapy, Adjuvant; Dacarbazine; Glioblastoma; Humans; O(6)-Methylguanine

2018
Treatment of Glioblastoma in the Elderly.
    Drugs & aging, 2018, Volume: 35, Issue:8

    Topics: Aged; Brain Neoplasms; Chemotherapy, Adjuvant; Dacarbazine; Glioblastoma; Humans; O(6)-Methylguanine

2018
Targeting autophagy for combating chemoresistance and radioresistance in glioblastoma.
    Apoptosis : an international journal on programmed cell death, 2018, Volume: 23, Issue:11-12

    Topics: Antineoplastic Agents; Autophagosomes; Autophagy; Brain Neoplasms; Cell Death; Drug Resistance, Neop

2018
Targeting autophagy for combating chemoresistance and radioresistance in glioblastoma.
    Apoptosis : an international journal on programmed cell death, 2018, Volume: 23, Issue:11-12

    Topics: Antineoplastic Agents; Autophagosomes; Autophagy; Brain Neoplasms; Cell Death; Drug Resistance, Neop

2018
Targeting autophagy for combating chemoresistance and radioresistance in glioblastoma.
    Apoptosis : an international journal on programmed cell death, 2018, Volume: 23, Issue:11-12

    Topics: Antineoplastic Agents; Autophagosomes; Autophagy; Brain Neoplasms; Cell Death; Drug Resistance, Neop

2018
Drug resistance in glioblastoma and cytotoxicity of seaweed compounds, alone and in combination with anticancer drugs: A mini review.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2018, Sep-15, Volume: 48

    Topics: Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Dacarbazine; Drug Resistance, Neoplas

2018
Drug resistance in glioblastoma and cytotoxicity of seaweed compounds, alone and in combination with anticancer drugs: A mini review.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2018, Sep-15, Volume: 48

    Topics: Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Dacarbazine; Drug Resistance, Neoplas

2018
Drug resistance in glioblastoma and cytotoxicity of seaweed compounds, alone and in combination with anticancer drugs: A mini review.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2018, Sep-15, Volume: 48

    Topics: Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Dacarbazine; Drug Resistance, Neoplas

2018
Potential Strategies Overcoming the Temozolomide Resistance for Glioblastoma.
    Neurologia medico-chirurgica, 2018, Oct-15, Volume: 58, Issue:10

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Drug Resistance, Neoplasm; Glioblastoma; Humans;

2018
Potential Strategies Overcoming the Temozolomide Resistance for Glioblastoma.
    Neurologia medico-chirurgica, 2018, Oct-15, Volume: 58, Issue:10

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Drug Resistance, Neoplasm; Glioblastoma; Humans;

2018
Potential Strategies Overcoming the Temozolomide Resistance for Glioblastoma.
    Neurologia medico-chirurgica, 2018, Oct-15, Volume: 58, Issue:10

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Drug Resistance, Neoplasm; Glioblastoma; Humans;

2018
Chemotherapy Treatment and Trials in Low-Grade Gliomas.
    Neurosurgery clinics of North America, 2019, Volume: 30, Issue:1

    Topics: Brain Neoplasms; Chemoradiotherapy; Drug Therapy; Drug-Related Side Effects and Adverse Reactions; G

2019
Chemotherapy Treatment and Trials in Low-Grade Gliomas.
    Neurosurgery clinics of North America, 2019, Volume: 30, Issue:1

    Topics: Brain Neoplasms; Chemoradiotherapy; Drug Therapy; Drug-Related Side Effects and Adverse Reactions; G

2019
Chemotherapy Treatment and Trials in Low-Grade Gliomas.
    Neurosurgery clinics of North America, 2019, Volume: 30, Issue:1

    Topics: Brain Neoplasms; Chemoradiotherapy; Drug Therapy; Drug-Related Side Effects and Adverse Reactions; G

2019
Anti-angiogenic therapy for high-grade glioma.
    The Cochrane database of systematic reviews, 2018, 11-22, Volume: 11

    Topics: Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Bevacizumab; Brai

2018
Anti-angiogenic therapy for high-grade glioma.
    The Cochrane database of systematic reviews, 2018, 11-22, Volume: 11

    Topics: Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Bevacizumab; Brai

2018
Anti-angiogenic therapy for high-grade glioma.
    The Cochrane database of systematic reviews, 2018, 11-22, Volume: 11

    Topics: Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Bevacizumab; Brai

2018
Treatment-induced brain tissue necrosis: a clinical challenge in neuro-oncology.
    Neuro-oncology, 2019, 09-06, Volume: 21, Issue:9

    Topics: Antineoplastic Agents, Alkylating; Brain; Brain Neoplasms; Chemoradiotherapy; Diagnosis, Differentia

2019
Treatment-induced brain tissue necrosis: a clinical challenge in neuro-oncology.
    Neuro-oncology, 2019, 09-06, Volume: 21, Issue:9

    Topics: Antineoplastic Agents, Alkylating; Brain; Brain Neoplasms; Chemoradiotherapy; Diagnosis, Differentia

2019
Treatment-induced brain tissue necrosis: a clinical challenge in neuro-oncology.
    Neuro-oncology, 2019, 09-06, Volume: 21, Issue:9

    Topics: Antineoplastic Agents, Alkylating; Brain; Brain Neoplasms; Chemoradiotherapy; Diagnosis, Differentia

2019
Evidence-Based Practice: Temozolomide Beyond Glioblastoma.
    Current oncology reports, 2019, 03-05, Volume: 21, Issue:4

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Evidence-Based Practice; Glioblastoma; Humans; T

2019
Evidence-Based Practice: Temozolomide Beyond Glioblastoma.
    Current oncology reports, 2019, 03-05, Volume: 21, Issue:4

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Evidence-Based Practice; Glioblastoma; Humans; T

2019
Evidence-Based Practice: Temozolomide Beyond Glioblastoma.
    Current oncology reports, 2019, 03-05, Volume: 21, Issue:4

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Evidence-Based Practice; Glioblastoma; Humans; T

2019
Hypofractionated versus standard radiation therapy in combination with temozolomide for glioblastoma in the elderly: a meta-analysis.
    Journal of neuro-oncology, 2019, Volume: 143, Issue:2

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Glioblastoma; Humans; Prognos

2019
Hypofractionated versus standard radiation therapy in combination with temozolomide for glioblastoma in the elderly: a meta-analysis.
    Journal of neuro-oncology, 2019, Volume: 143, Issue:2

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Glioblastoma; Humans; Prognos

2019
Hypofractionated versus standard radiation therapy in combination with temozolomide for glioblastoma in the elderly: a meta-analysis.
    Journal of neuro-oncology, 2019, Volume: 143, Issue:2

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Glioblastoma; Humans; Prognos

2019
From epidemiology and neurometabolism to treatment: Vitamin D in pathogenesis of glioblastoma Multiforme (GBM) and a proposal for Vitamin D + all-trans retinoic acid + Temozolomide combination in treatment of GBM.
    Metabolic brain disease, 2019, Volume: 34, Issue:3

    Topics: Brain Neoplasms; Glioblastoma; Humans; Receptors, Calcitriol; Temozolomide; Tretinoin; Vitamin D

2019
From epidemiology and neurometabolism to treatment: Vitamin D in pathogenesis of glioblastoma Multiforme (GBM) and a proposal for Vitamin D + all-trans retinoic acid + Temozolomide combination in treatment of GBM.
    Metabolic brain disease, 2019, Volume: 34, Issue:3

    Topics: Brain Neoplasms; Glioblastoma; Humans; Receptors, Calcitriol; Temozolomide; Tretinoin; Vitamin D

2019
From epidemiology and neurometabolism to treatment: Vitamin D in pathogenesis of glioblastoma Multiforme (GBM) and a proposal for Vitamin D + all-trans retinoic acid + Temozolomide combination in treatment of GBM.
    Metabolic brain disease, 2019, Volume: 34, Issue:3

    Topics: Brain Neoplasms; Glioblastoma; Humans; Receptors, Calcitriol; Temozolomide; Tretinoin; Vitamin D

2019
Survival Benefit of Maximal Resection for Glioblastoma Reoperation in the Temozolomide Era: A Meta-Analysis.
    World neurosurgery, 2019, Volume: 127

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Glioblastoma; Humans; Reoperation; Temozolomide;

2019
Survival Benefit of Maximal Resection for Glioblastoma Reoperation in the Temozolomide Era: A Meta-Analysis.
    World neurosurgery, 2019, Volume: 127

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Glioblastoma; Humans; Reoperation; Temozolomide;

2019
Survival Benefit of Maximal Resection for Glioblastoma Reoperation in the Temozolomide Era: A Meta-Analysis.
    World neurosurgery, 2019, Volume: 127

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Glioblastoma; Humans; Reoperation; Temozolomide;

2019
DNA repair in personalized brain cancer therapy with temozolomide and nitrosoureas.
    DNA repair, 2019, Volume: 78

    Topics: Brain Neoplasms; Cell Death; DNA Repair; Humans; Nitrosourea Compounds; Precision Medicine; Temozolo

2019
DNA repair in personalized brain cancer therapy with temozolomide and nitrosoureas.
    DNA repair, 2019, Volume: 78

    Topics: Brain Neoplasms; Cell Death; DNA Repair; Humans; Nitrosourea Compounds; Precision Medicine; Temozolo

2019
DNA repair in personalized brain cancer therapy with temozolomide and nitrosoureas.
    DNA repair, 2019, Volume: 78

    Topics: Brain Neoplasms; Cell Death; DNA Repair; Humans; Nitrosourea Compounds; Precision Medicine; Temozolo

2019
Aberrant Transcriptional Regulation of Super-enhancers by RET Finger Protein-histone Deacetylase 1 Complex in Glioblastoma: Chemoresistance to Temozolomide.
    Neurologia medico-chirurgica, 2019, Aug-15, Volume: 59, Issue:8

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Drug Resistance, Neoplasm; Gene Expression Regul

2019
Aberrant Transcriptional Regulation of Super-enhancers by RET Finger Protein-histone Deacetylase 1 Complex in Glioblastoma: Chemoresistance to Temozolomide.
    Neurologia medico-chirurgica, 2019, Aug-15, Volume: 59, Issue:8

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Drug Resistance, Neoplasm; Gene Expression Regul

2019
Aberrant Transcriptional Regulation of Super-enhancers by RET Finger Protein-histone Deacetylase 1 Complex in Glioblastoma: Chemoresistance to Temozolomide.
    Neurologia medico-chirurgica, 2019, Aug-15, Volume: 59, Issue:8

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Drug Resistance, Neoplasm; Gene Expression Regul

2019
The combination of carmustine wafers and temozolomide for the treatment of malignant gliomas. A comprehensive review of the rationale and clinical experience.
    Journal of neuro-oncology, 2013, Volume: 113, Issue:2

    Topics: Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carmustine; Clinical Trials as Topi

2013
The combination of carmustine wafers and temozolomide for the treatment of malignant gliomas. A comprehensive review of the rationale and clinical experience.
    Journal of neuro-oncology, 2013, Volume: 113, Issue:2

    Topics: Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carmustine; Clinical Trials as Topi

2013
The combination of carmustine wafers and temozolomide for the treatment of malignant gliomas. A comprehensive review of the rationale and clinical experience.
    Journal of neuro-oncology, 2013, Volume: 113, Issue:2

    Topics: Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carmustine; Clinical Trials as Topi

2013
Essential role of Gli proteins in glioblastoma multiforme.
    Current protein & peptide science, 2013, Volume: 14, Issue:2

    Topics: Antineoplastic Agents; Brain Neoplasms; Dacarbazine; Drug Resistance, Neoplasm; Glioblastoma; Hedgeh

2013
Essential role of Gli proteins in glioblastoma multiforme.
    Current protein & peptide science, 2013, Volume: 14, Issue:2

    Topics: Antineoplastic Agents; Brain Neoplasms; Dacarbazine; Drug Resistance, Neoplasm; Glioblastoma; Hedgeh

2013
Essential role of Gli proteins in glioblastoma multiforme.
    Current protein & peptide science, 2013, Volume: 14, Issue:2

    Topics: Antineoplastic Agents; Brain Neoplasms; Dacarbazine; Drug Resistance, Neoplasm; Glioblastoma; Hedgeh

2013
Pseudoprogression after glioma therapy: a comprehensive review.
    Expert review of neurotherapeutics, 2013, Volume: 13, Issue:4

    Topics: Antineoplastic Agents; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease Progression;

2013
Pseudoprogression after glioma therapy: a comprehensive review.
    Expert review of neurotherapeutics, 2013, Volume: 13, Issue:4

    Topics: Antineoplastic Agents; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease Progression;

2013
Pseudoprogression after glioma therapy: a comprehensive review.
    Expert review of neurotherapeutics, 2013, Volume: 13, Issue:4

    Topics: Antineoplastic Agents; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease Progression;

2013
A conceptually new treatment approach for relapsed glioblastoma: coordinated undermining of survival paths with nine repurposed drugs (CUSP9) by the International Initiative for Accelerated Improvement of Glioblastoma Care.
    Oncotarget, 2013, Volume: 4, Issue:4

    Topics: Antineoplastic Combined Chemotherapy Protocols; Aprepitant; Artemisinins; Auranofin; Brain Neoplasms

2013
A conceptually new treatment approach for relapsed glioblastoma: coordinated undermining of survival paths with nine repurposed drugs (CUSP9) by the International Initiative for Accelerated Improvement of Glioblastoma Care.
    Oncotarget, 2013, Volume: 4, Issue:4

    Topics: Antineoplastic Combined Chemotherapy Protocols; Aprepitant; Artemisinins; Auranofin; Brain Neoplasms

2013
A conceptually new treatment approach for relapsed glioblastoma: coordinated undermining of survival paths with nine repurposed drugs (CUSP9) by the International Initiative for Accelerated Improvement of Glioblastoma Care.
    Oncotarget, 2013, Volume: 4, Issue:4

    Topics: Antineoplastic Combined Chemotherapy Protocols; Aprepitant; Artemisinins; Auranofin; Brain Neoplasms

2013
Temozolomide for high grade glioma.
    The Cochrane database of systematic reviews, 2013, Apr-30, Issue:4

    Topics: Age Factors; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Glioblastoma; Humans;

2013
Temozolomide for high grade glioma.
    The Cochrane database of systematic reviews, 2013, Apr-30, Issue:4

    Topics: Age Factors; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Glioblastoma; Humans;

2013
Temozolomide for high grade glioma.
    The Cochrane database of systematic reviews, 2013, Apr-30, Issue:4

    Topics: Age Factors; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Glioblastoma; Humans;

2013
Treatment recommendations for anaplastic oligodendrogliomas that are codeleted.
    Oncology (Williston Park, N.Y.), 2013, Volume: 27, Issue:4

    Topics: Brain Neoplasms; Dacarbazine; Humans; Isocitrate Dehydrogenase; Mutation; Oligodendroglioma; Temozol

2013
Treatment recommendations for anaplastic oligodendrogliomas that are codeleted.
    Oncology (Williston Park, N.Y.), 2013, Volume: 27, Issue:4

    Topics: Brain Neoplasms; Dacarbazine; Humans; Isocitrate Dehydrogenase; Mutation; Oligodendroglioma; Temozol

2013
Treatment recommendations for anaplastic oligodendrogliomas that are codeleted.
    Oncology (Williston Park, N.Y.), 2013, Volume: 27, Issue:4

    Topics: Brain Neoplasms; Dacarbazine; Humans; Isocitrate Dehydrogenase; Mutation; Oligodendroglioma; Temozol

2013
Epigenetic pathways and glioblastoma treatment.
    Epigenetics, 2013, Volume: 8, Issue:8

    Topics: Adult; Animals; Brain Neoplasms; Dacarbazine; Drug Discovery; Epigenesis, Genetic; Gene Regulatory N

2013
Epigenetic pathways and glioblastoma treatment.
    Epigenetics, 2013, Volume: 8, Issue:8

    Topics: Adult; Animals; Brain Neoplasms; Dacarbazine; Drug Discovery; Epigenesis, Genetic; Gene Regulatory N

2013
Epigenetic pathways and glioblastoma treatment.
    Epigenetics, 2013, Volume: 8, Issue:8

    Topics: Adult; Animals; Brain Neoplasms; Dacarbazine; Drug Discovery; Epigenesis, Genetic; Gene Regulatory N

2013
Update in the treatment of high-grade Gliomas.
    Neurologic clinics, 2013, Volume: 31, Issue:3

    Topics: Antineoplastic Agents; Brain Neoplasms; Dacarbazine; Drug Therapy, Combination; Glioma; Humans; Magn

2013
Update in the treatment of high-grade Gliomas.
    Neurologic clinics, 2013, Volume: 31, Issue:3

    Topics: Antineoplastic Agents; Brain Neoplasms; Dacarbazine; Drug Therapy, Combination; Glioma; Humans; Magn

2013
Update in the treatment of high-grade Gliomas.
    Neurologic clinics, 2013, Volume: 31, Issue:3

    Topics: Antineoplastic Agents; Brain Neoplasms; Dacarbazine; Drug Therapy, Combination; Glioma; Humans; Magn

2013
Radiotherapy plus concurrent or sequential temozolomide for glioblastoma in the elderly: a meta-analysis.
    PloS one, 2013, Volume: 8, Issue:9

    Topics: Aged; Antineoplastic Agents; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Glioblastoma;

2013
Radiotherapy plus concurrent or sequential temozolomide for glioblastoma in the elderly: a meta-analysis.
    PloS one, 2013, Volume: 8, Issue:9

    Topics: Aged; Antineoplastic Agents; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Glioblastoma;

2013
Radiotherapy plus concurrent or sequential temozolomide for glioblastoma in the elderly: a meta-analysis.
    PloS one, 2013, Volume: 8, Issue:9

    Topics: Aged; Antineoplastic Agents; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Glioblastoma;

2013
Elderly patients with glioblastoma: the treatment challenge.
    Expert review of neurotherapeutics, 2013, Volume: 13, Issue:10

    Topics: Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Gl

2013
Elderly patients with glioblastoma: the treatment challenge.
    Expert review of neurotherapeutics, 2013, Volume: 13, Issue:10

    Topics: Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Gl

2013
Elderly patients with glioblastoma: the treatment challenge.
    Expert review of neurotherapeutics, 2013, Volume: 13, Issue:10

    Topics: Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Gl

2013
O6-methylguanine DNA methyltransferase as a promising target for the treatment of temozolomide-resistant gliomas.
    Cell death & disease, 2013, Oct-24, Volume: 4

    Topics: Animals; Brain Neoplasms; Dacarbazine; Drug Resistance, Neoplasm; Glioma; Humans; Molecular Targeted

2013
O6-methylguanine DNA methyltransferase as a promising target for the treatment of temozolomide-resistant gliomas.
    Cell death & disease, 2013, Oct-24, Volume: 4

    Topics: Animals; Brain Neoplasms; Dacarbazine; Drug Resistance, Neoplasm; Glioma; Humans; Molecular Targeted

2013
O6-methylguanine DNA methyltransferase as a promising target for the treatment of temozolomide-resistant gliomas.
    Cell death & disease, 2013, Oct-24, Volume: 4

    Topics: Animals; Brain Neoplasms; Dacarbazine; Drug Resistance, Neoplasm; Glioma; Humans; Molecular Targeted

2013
A meta-analysis of temozolomide versus radiotherapy in elderly glioblastoma patients.
    Journal of neuro-oncology, 2014, Volume: 116, Issue:2

    Topics: Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Databases,

2014
A meta-analysis of temozolomide versus radiotherapy in elderly glioblastoma patients.
    Journal of neuro-oncology, 2014, Volume: 116, Issue:2

    Topics: Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Databases,

2014
A meta-analysis of temozolomide versus radiotherapy in elderly glioblastoma patients.
    Journal of neuro-oncology, 2014, Volume: 116, Issue:2

    Topics: Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Databases,

2014
Radiation and concomitant chemotherapy for patients with glioblastoma multiforme.
    Chinese journal of cancer, 2014, Volume: 33, Issue:1

    Topics: Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Dacarbazine; DNA Methyl

2014
Radiation and concomitant chemotherapy for patients with glioblastoma multiforme.
    Chinese journal of cancer, 2014, Volume: 33, Issue:1

    Topics: Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Dacarbazine; DNA Methyl

2014
Radiation and concomitant chemotherapy for patients with glioblastoma multiforme.
    Chinese journal of cancer, 2014, Volume: 33, Issue:1

    Topics: Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Dacarbazine; DNA Methyl

2014
High-grade glioma in elderly patients: can the oncogeriatrician help?
    Clinical interventions in aging, 2013, Volume: 8

    Topics: Age Factors; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Da

2013
High-grade glioma in elderly patients: can the oncogeriatrician help?
    Clinical interventions in aging, 2013, Volume: 8

    Topics: Age Factors; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Da

2013
High-grade glioma in elderly patients: can the oncogeriatrician help?
    Clinical interventions in aging, 2013, Volume: 8

    Topics: Age Factors; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Da

2013
Radiotherapy of high-grade gliomas: current standards and new concepts, innovations in imaging and radiotherapy, and new therapeutic approaches.
    Chinese journal of cancer, 2014, Volume: 33, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Diffusion Tensor Imaging; Glioblast

2014
Radiotherapy of high-grade gliomas: current standards and new concepts, innovations in imaging and radiotherapy, and new therapeutic approaches.
    Chinese journal of cancer, 2014, Volume: 33, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Diffusion Tensor Imaging; Glioblast

2014
Radiotherapy of high-grade gliomas: current standards and new concepts, innovations in imaging and radiotherapy, and new therapeutic approaches.
    Chinese journal of cancer, 2014, Volume: 33, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Diffusion Tensor Imaging; Glioblast

2014
MicroRNA as potential modulators in chemoresistant high-grade gliomas.
    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2014, Volume: 21, Issue:3

    Topics: Antineoplastic Agents; Brain Neoplasms; Dacarbazine; Drug Resistance, Neoplasm; Glioma; Humans; Micr

2014
MicroRNA as potential modulators in chemoresistant high-grade gliomas.
    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2014, Volume: 21, Issue:3

    Topics: Antineoplastic Agents; Brain Neoplasms; Dacarbazine; Drug Resistance, Neoplasm; Glioma; Humans; Micr

2014
MicroRNA as potential modulators in chemoresistant high-grade gliomas.
    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2014, Volume: 21, Issue:3

    Topics: Antineoplastic Agents; Brain Neoplasms; Dacarbazine; Drug Resistance, Neoplasm; Glioma; Humans; Micr

2014
Treatment options and outcomes for glioblastoma in the elderly patient.
    Clinical interventions in aging, 2014, Volume: 9

    Topics: Age Factors; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Glioblastoma; Hu

2014
Treatment options and outcomes for glioblastoma in the elderly patient.
    Clinical interventions in aging, 2014, Volume: 9

    Topics: Age Factors; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Glioblastoma; Hu

2014
Treatment options and outcomes for glioblastoma in the elderly patient.
    Clinical interventions in aging, 2014, Volume: 9

    Topics: Age Factors; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Glioblastoma; Hu

2014
[Radiotherapy plus concomitant systemic therapies for patients with brain metastases from breast cancer].
    Cancer radiotherapie : journal de la Societe francaise de radiotherapie oncologique, 2014, Volume: 18, Issue:3

    Topics: Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Blood-Brain Barri

2014
[Radiotherapy plus concomitant systemic therapies for patients with brain metastases from breast cancer].
    Cancer radiotherapie : journal de la Societe francaise de radiotherapie oncologique, 2014, Volume: 18, Issue:3

    Topics: Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Blood-Brain Barri

2014
[Radiotherapy plus concomitant systemic therapies for patients with brain metastases from breast cancer].
    Cancer radiotherapie : journal de la Societe francaise de radiotherapie oncologique, 2014, Volume: 18, Issue:3

    Topics: Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Blood-Brain Barri

2014
The role of cytotoxic chemotherapy in the management of progressive glioblastoma : a systematic review and evidence-based clinical practice guideline.
    Journal of neuro-oncology, 2014, Volume: 118, Issue:3

    Topics: Absorbable Implants; Adult; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; B

2014
The role of cytotoxic chemotherapy in the management of progressive glioblastoma : a systematic review and evidence-based clinical practice guideline.
    Journal of neuro-oncology, 2014, Volume: 118, Issue:3

    Topics: Absorbable Implants; Adult; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; B

2014
The role of cytotoxic chemotherapy in the management of progressive glioblastoma : a systematic review and evidence-based clinical practice guideline.
    Journal of neuro-oncology, 2014, Volume: 118, Issue:3

    Topics: Absorbable Implants; Adult; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; B

2014
Straying from the path in neuro-oncology.
    Neuro-oncology, 2014, Volume: 16, Issue:8

    Topics: Brain Neoplasms; Clinical Trials as Topic; Dacarbazine; Humans; Medical Oncology; Temozolomide

2014
Straying from the path in neuro-oncology.
    Neuro-oncology, 2014, Volume: 16, Issue:8

    Topics: Brain Neoplasms; Clinical Trials as Topic; Dacarbazine; Humans; Medical Oncology; Temozolomide

2014
Straying from the path in neuro-oncology.
    Neuro-oncology, 2014, Volume: 16, Issue:8

    Topics: Brain Neoplasms; Clinical Trials as Topic; Dacarbazine; Humans; Medical Oncology; Temozolomide

2014
Current evidence of temozolomide and bevacizumab in treatment of gliomas.
    Neurological research, 2015, Volume: 37, Issue:2

    Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Antineop

2015
Current evidence of temozolomide and bevacizumab in treatment of gliomas.
    Neurological research, 2015, Volume: 37, Issue:2

    Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Antineop

2015
Current evidence of temozolomide and bevacizumab in treatment of gliomas.
    Neurological research, 2015, Volume: 37, Issue:2

    Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Antineop

2015
Predictive biomarkers investigated in glioblastoma.
    Expert review of molecular diagnostics, 2014, Volume: 14, Issue:7

    Topics: Angiogenesis Inhibitors; Antineoplastic Agents, Alkylating; Biomarkers, Tumor; Brain Neoplasms; Daca

2014
Predictive biomarkers investigated in glioblastoma.
    Expert review of molecular diagnostics, 2014, Volume: 14, Issue:7

    Topics: Angiogenesis Inhibitors; Antineoplastic Agents, Alkylating; Biomarkers, Tumor; Brain Neoplasms; Daca

2014
Predictive biomarkers investigated in glioblastoma.
    Expert review of molecular diagnostics, 2014, Volume: 14, Issue:7

    Topics: Angiogenesis Inhibitors; Antineoplastic Agents, Alkylating; Biomarkers, Tumor; Brain Neoplasms; Daca

2014
Molecular neuro-oncology and the challenge of the blood-brain barrier.
    Seminars in oncology, 2014, Volume: 41, Issue:4

    Topics: Animals; Blood-Brain Barrier; Brain Neoplasms; Chromosome Deletion; Dacarbazine; DNA Modification Me

2014
Molecular neuro-oncology and the challenge of the blood-brain barrier.
    Seminars in oncology, 2014, Volume: 41, Issue:4

    Topics: Animals; Blood-Brain Barrier; Brain Neoplasms; Chromosome Deletion; Dacarbazine; DNA Modification Me

2014
Molecular neuro-oncology and the challenge of the blood-brain barrier.
    Seminars in oncology, 2014, Volume: 41, Issue:4

    Topics: Animals; Blood-Brain Barrier; Brain Neoplasms; Chromosome Deletion; Dacarbazine; DNA Modification Me

2014
[Management of gliomas].
    Cancer radiotherapie : journal de la Societe francaise de radiotherapie oncologique, 2014, Volume: 18, Issue:5-6

    Topics: Age Factors; Antibodies, Monoclonal, Humanized; Antineoplastic Agents, Alkylating; Antineoplastic Co

2014
[Management of gliomas].
    Cancer radiotherapie : journal de la Societe francaise de radiotherapie oncologique, 2014, Volume: 18, Issue:5-6

    Topics: Age Factors; Antibodies, Monoclonal, Humanized; Antineoplastic Agents, Alkylating; Antineoplastic Co

2014
[Management of gliomas].
    Cancer radiotherapie : journal de la Societe francaise de radiotherapie oncologique, 2014, Volume: 18, Issue:5-6

    Topics: Age Factors; Antibodies, Monoclonal, Humanized; Antineoplastic Agents, Alkylating; Antineoplastic Co

2014
Management of high-grade gliomas in the elderly.
    Seminars in radiation oncology, 2014, Volume: 24, Issue:4

    Topics: Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Thera

2014
Management of high-grade gliomas in the elderly.
    Seminars in radiation oncology, 2014, Volume: 24, Issue:4

    Topics: Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Thera

2014
Management of high-grade gliomas in the elderly.
    Seminars in radiation oncology, 2014, Volume: 24, Issue:4

    Topics: Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Thera

2014
Treatment of brain metastases.
    Oncology, 2014, Volume: 87, Issue:6

    Topics: Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic A

2014
Treatment of brain metastases.
    Oncology, 2014, Volume: 87, Issue:6

    Topics: Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic A

2014
Treatment of brain metastases.
    Oncology, 2014, Volume: 87, Issue:6

    Topics: Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic A

2014
Antiangiogenic therapy for high-grade glioma.
    The Cochrane database of systematic reviews, 2014, Sep-22, Issue:9

    Topics: Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Bevacizumab; Brai

2014
Antiangiogenic therapy for high-grade glioma.
    The Cochrane database of systematic reviews, 2014, Sep-22, Issue:9

    Topics: Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Bevacizumab; Brai

2014
Antiangiogenic therapy for high-grade glioma.
    The Cochrane database of systematic reviews, 2014, Sep-22, Issue:9

    Topics: Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Bevacizumab; Brai

2014
Emerging therapies for glioblastoma.
    JAMA neurology, 2014, Volume: 71, Issue:11

    Topics: Animals; Blood-Brain Barrier; Brain Neoplasms; Cell- and Tissue-Based Therapy; Dacarbazine; Glioblas

2014
Emerging therapies for glioblastoma.
    JAMA neurology, 2014, Volume: 71, Issue:11

    Topics: Animals; Blood-Brain Barrier; Brain Neoplasms; Cell- and Tissue-Based Therapy; Dacarbazine; Glioblas

2014
Emerging therapies for glioblastoma.
    JAMA neurology, 2014, Volume: 71, Issue:11

    Topics: Animals; Blood-Brain Barrier; Brain Neoplasms; Cell- and Tissue-Based Therapy; Dacarbazine; Glioblas

2014
Comprehensive analysis of temozolomide treatment for patients with glioma.
    Asian Pacific journal of cancer prevention : APJCP, 2014, Volume: 15, Issue:19

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Glioma; Humans; Prognosis; Temozolo

2014
Comprehensive analysis of temozolomide treatment for patients with glioma.
    Asian Pacific journal of cancer prevention : APJCP, 2014, Volume: 15, Issue:19

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Glioma; Humans; Prognosis; Temozolo

2014
Comprehensive analysis of temozolomide treatment for patients with glioma.
    Asian Pacific journal of cancer prevention : APJCP, 2014, Volume: 15, Issue:19

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Glioma; Humans; Prognosis; Temozolo

2014
Glioblastoma survival: has it improved? Evidence from population-based studies.
    Current opinion in neurology, 2014, Volume: 27, Issue:6

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Community Health Planning; Dacarbazine; Glioblas

2014
Glioblastoma survival: has it improved? Evidence from population-based studies.
    Current opinion in neurology, 2014, Volume: 27, Issue:6

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Community Health Planning; Dacarbazine; Glioblas

2014
Glioblastoma survival: has it improved? Evidence from population-based studies.
    Current opinion in neurology, 2014, Volume: 27, Issue:6

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Community Health Planning; Dacarbazine; Glioblas

2014
Treatment considerations for MGMT-unmethylated glioblastoma.
    Current neurology and neuroscience reports, 2015, Volume: 15, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; DNA Methylation; DNA Modification M

2015
Treatment considerations for MGMT-unmethylated glioblastoma.
    Current neurology and neuroscience reports, 2015, Volume: 15, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; DNA Methylation; DNA Modification M

2015
Treatment considerations for MGMT-unmethylated glioblastoma.
    Current neurology and neuroscience reports, 2015, Volume: 15, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; DNA Methylation; DNA Modification M

2015
Economics of Malignant Gliomas: A Critical Review.
    Journal of oncology practice, 2015, Volume: 11, Issue:1

    Topics: Brain Neoplasms; Canada; Cost of Illness; Costs and Cost Analysis; Dacarbazine; Drug Therapy; Europe

2015
Economics of Malignant Gliomas: A Critical Review.
    Journal of oncology practice, 2015, Volume: 11, Issue:1

    Topics: Brain Neoplasms; Canada; Cost of Illness; Costs and Cost Analysis; Dacarbazine; Drug Therapy; Europe

2015
Economics of Malignant Gliomas: A Critical Review.
    Journal of oncology practice, 2015, Volume: 11, Issue:1

    Topics: Brain Neoplasms; Canada; Cost of Illness; Costs and Cost Analysis; Dacarbazine; Drug Therapy; Europe

2015
Glioblastoma in the elderly.
    Cancer treatment and research, 2015, Volume: 163

    Topics: Aged; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; DNA Modification Methylases; DNA Repa

2015
Glioblastoma in the elderly.
    Cancer treatment and research, 2015, Volume: 163

    Topics: Aged; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; DNA Modification Methylases; DNA Repa

2015
Glioblastoma in the elderly.
    Cancer treatment and research, 2015, Volume: 163

    Topics: Aged; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; DNA Modification Methylases; DNA Repa

2015
Astrocytoma malignum in glioblastoma multiforme vertens with long term survival--case report and a literature review.
    Przeglad lekarski, 2014, Volume: 71, Issue:8

    Topics: Adult; Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neoplasms; Chemoradiotherapy, Adjuvant;

2014
Astrocytoma malignum in glioblastoma multiforme vertens with long term survival--case report and a literature review.
    Przeglad lekarski, 2014, Volume: 71, Issue:8

    Topics: Adult; Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neoplasms; Chemoradiotherapy, Adjuvant;

2014
Astrocytoma malignum in glioblastoma multiforme vertens with long term survival--case report and a literature review.
    Przeglad lekarski, 2014, Volume: 71, Issue:8

    Topics: Adult; Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neoplasms; Chemoradiotherapy, Adjuvant;

2014
The evolution of the EGFRvIII (rindopepimut) immunotherapy for glioblastoma multiforme patients.
    Human vaccines & immunotherapeutics, 2014, Volume: 10, Issue:11

    Topics: Animals; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Bevacizu

2014
The evolution of the EGFRvIII (rindopepimut) immunotherapy for glioblastoma multiforme patients.
    Human vaccines & immunotherapeutics, 2014, Volume: 10, Issue:11

    Topics: Animals; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Bevacizu

2014
The evolution of the EGFRvIII (rindopepimut) immunotherapy for glioblastoma multiforme patients.
    Human vaccines & immunotherapeutics, 2014, Volume: 10, Issue:11

    Topics: Animals; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Bevacizu

2014
[Elderly patients with glioblastoma: state of the art].
    Bulletin du cancer, 2015, Volume: 102, Issue:3

    Topics: Age Factors; Aged; Antibodies, Monoclonal, Humanized; Antineoplastic Agents, Alkylating; Bevacizumab

2015
[Elderly patients with glioblastoma: state of the art].
    Bulletin du cancer, 2015, Volume: 102, Issue:3

    Topics: Age Factors; Aged; Antibodies, Monoclonal, Humanized; Antineoplastic Agents, Alkylating; Bevacizumab

2015
[Elderly patients with glioblastoma: state of the art].
    Bulletin du cancer, 2015, Volume: 102, Issue:3

    Topics: Age Factors; Aged; Antibodies, Monoclonal, Humanized; Antineoplastic Agents, Alkylating; Bevacizumab

2015
Toward an effective strategy in glioblastoma treatment. Part I: resistance mechanisms and strategies to overcome resistance of glioblastoma to temozolomide.
    Drug discovery today, 2015, Volume: 20, Issue:7

    Topics: Animals; Antineoplastic Agents, Alkylating; Biomarkers, Tumor; Brain Neoplasms; Dacarbazine; Drug De

2015
Toward an effective strategy in glioblastoma treatment. Part I: resistance mechanisms and strategies to overcome resistance of glioblastoma to temozolomide.
    Drug discovery today, 2015, Volume: 20, Issue:7

    Topics: Animals; Antineoplastic Agents, Alkylating; Biomarkers, Tumor; Brain Neoplasms; Dacarbazine; Drug De

2015
Toward an effective strategy in glioblastoma treatment. Part I: resistance mechanisms and strategies to overcome resistance of glioblastoma to temozolomide.
    Drug discovery today, 2015, Volume: 20, Issue:7

    Topics: Animals; Antineoplastic Agents, Alkylating; Biomarkers, Tumor; Brain Neoplasms; Dacarbazine; Drug De

2015
Severe cholestatic hepatitis due to temozolomide: an adverse drug effect to keep in mind. Case report and review of literature.
    Medicine, 2015, Volume: 94, Issue:12

    Topics: Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemical and Drug Induced Liver Injury; Ch

2015
Severe cholestatic hepatitis due to temozolomide: an adverse drug effect to keep in mind. Case report and review of literature.
    Medicine, 2015, Volume: 94, Issue:12

    Topics: Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemical and Drug Induced Liver Injury; Ch

2015
Severe cholestatic hepatitis due to temozolomide: an adverse drug effect to keep in mind. Case report and review of literature.
    Medicine, 2015, Volume: 94, Issue:12

    Topics: Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemical and Drug Induced Liver Injury; Ch

2015
Low-grade gliomas.
    Continuum (Minneapolis, Minn.), 2015, Volume: 21, Issue:2 Neuro-on

    Topics: Antineoplastic Agents; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease Progression;

2015
Low-grade gliomas.
    Continuum (Minneapolis, Minn.), 2015, Volume: 21, Issue:2 Neuro-on

    Topics: Antineoplastic Agents; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease Progression;

2015
Low-grade gliomas.
    Continuum (Minneapolis, Minn.), 2015, Volume: 21, Issue:2 Neuro-on

    Topics: Antineoplastic Agents; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease Progression;

2015
Long-term temozolomide might be an optimal choice for patient with multifocal glioblastoma, especially with deep-seated structure involvement: a case report and literature review.
    World journal of surgical oncology, 2015, Apr-09, Volume: 13

    Topics: Adult; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Combined Modality Ther

2015
Long-term temozolomide might be an optimal choice for patient with multifocal glioblastoma, especially with deep-seated structure involvement: a case report and literature review.
    World journal of surgical oncology, 2015, Apr-09, Volume: 13

    Topics: Adult; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Combined Modality Ther

2015
Long-term temozolomide might be an optimal choice for patient with multifocal glioblastoma, especially with deep-seated structure involvement: a case report and literature review.
    World journal of surgical oncology, 2015, Apr-09, Volume: 13

    Topics: Adult; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Combined Modality Ther

2015
Toward an effective strategy in glioblastoma treatment. Part II: RNA interference as a promising way to sensitize glioblastomas to temozolomide.
    Drug discovery today, 2015, Volume: 20, Issue:6

    Topics: Animals; Antineoplastic Agents, Alkylating; Biomarkers, Tumor; Brain Neoplasms; Dacarbazine; Drug Re

2015
Toward an effective strategy in glioblastoma treatment. Part II: RNA interference as a promising way to sensitize glioblastomas to temozolomide.
    Drug discovery today, 2015, Volume: 20, Issue:6

    Topics: Animals; Antineoplastic Agents, Alkylating; Biomarkers, Tumor; Brain Neoplasms; Dacarbazine; Drug Re

2015
Toward an effective strategy in glioblastoma treatment. Part II: RNA interference as a promising way to sensitize glioblastomas to temozolomide.
    Drug discovery today, 2015, Volume: 20, Issue:6

    Topics: Animals; Antineoplastic Agents, Alkylating; Biomarkers, Tumor; Brain Neoplasms; Dacarbazine; Drug Re

2015
Chemoresistance and chemotherapy targeting stem-like cells in malignant glioma.
    Advances in experimental medicine and biology, 2015, Volume: 853

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; DNA Mismatch Repair; DNA M

2015
Chemoresistance and chemotherapy targeting stem-like cells in malignant glioma.
    Advances in experimental medicine and biology, 2015, Volume: 853

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; DNA Mismatch Repair; DNA M

2015
Chemoresistance and chemotherapy targeting stem-like cells in malignant glioma.
    Advances in experimental medicine and biology, 2015, Volume: 853

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; DNA Mismatch Repair; DNA M

2015
Therapeutic management of gliosarcoma in the temozolomide era.
    CNS oncology, 2015, Volume: 4, Issue:3

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Disease Management; Gliosarcoma; Hu

2015
Therapeutic management of gliosarcoma in the temozolomide era.
    CNS oncology, 2015, Volume: 4, Issue:3

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Disease Management; Gliosarcoma; Hu

2015
Therapeutic management of gliosarcoma in the temozolomide era.
    CNS oncology, 2015, Volume: 4, Issue:3

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Disease Management; Gliosarcoma; Hu

2015
Economic Evaluation of Bevacizumab for the First-Line Treatment of Newly Diagnosed Glioblastoma Multiforme.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2015, Jul-10, Volume: 33, Issue:20

    Topics: Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Pro

2015
Economic Evaluation of Bevacizumab for the First-Line Treatment of Newly Diagnosed Glioblastoma Multiforme.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2015, Jul-10, Volume: 33, Issue:20

    Topics: Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Pro

2015
Economic Evaluation of Bevacizumab for the First-Line Treatment of Newly Diagnosed Glioblastoma Multiforme.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2015, Jul-10, Volume: 33, Issue:20

    Topics: Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Pro

2015
Intracranial fibrosarcoma treated with adjuvant radiation and temozolomide: Report of a case and review of all published cases.
    Journal of the Egyptian National Cancer Institute, 2016, Volume: 28, Issue:2

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant;

2016
Intracranial fibrosarcoma treated with adjuvant radiation and temozolomide: Report of a case and review of all published cases.
    Journal of the Egyptian National Cancer Institute, 2016, Volume: 28, Issue:2

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant;

2016
Intracranial fibrosarcoma treated with adjuvant radiation and temozolomide: Report of a case and review of all published cases.
    Journal of the Egyptian National Cancer Institute, 2016, Volume: 28, Issue:2

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant;

2016
The efficacy and safety of various dose-dense regimens of temozolomide for recurrent high-grade glioma: a systematic review with meta-analysis.
    Journal of neuro-oncology, 2015, Volume: 125, Issue:2

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Glioma; Humans; Neoplasm Recurrence

2015
The efficacy and safety of various dose-dense regimens of temozolomide for recurrent high-grade glioma: a systematic review with meta-analysis.
    Journal of neuro-oncology, 2015, Volume: 125, Issue:2

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Glioma; Humans; Neoplasm Recurrence

2015
The efficacy and safety of various dose-dense regimens of temozolomide for recurrent high-grade glioma: a systematic review with meta-analysis.
    Journal of neuro-oncology, 2015, Volume: 125, Issue:2

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Glioma; Humans; Neoplasm Recurrence

2015
Temozolomide for Treating Malignant Melanoma.
    Journal of the College of Physicians and Surgeons--Pakistan : JCPSP, 2015, Volume: 25, Issue:9

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Humans; Melanoma; Melanoma, Cutaneo

2015
Temozolomide for Treating Malignant Melanoma.
    Journal of the College of Physicians and Surgeons--Pakistan : JCPSP, 2015, Volume: 25, Issue:9

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Humans; Melanoma; Melanoma, Cutaneo

2015
Temozolomide for Treating Malignant Melanoma.
    Journal of the College of Physicians and Surgeons--Pakistan : JCPSP, 2015, Volume: 25, Issue:9

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Humans; Melanoma; Melanoma, Cutaneo

2015
Comparison of the effectiveness of whole-brain radiotherapy plus temozolomide versus whole-brain radiotherapy in treating brain metastases based on a systematic review of randomized controlled trials.
    Anti-cancer drugs, 2016, Volume: 27, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Humans;

2016
Comparison of the effectiveness of whole-brain radiotherapy plus temozolomide versus whole-brain radiotherapy in treating brain metastases based on a systematic review of randomized controlled trials.
    Anti-cancer drugs, 2016, Volume: 27, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Humans;

2016
Comparison of the effectiveness of whole-brain radiotherapy plus temozolomide versus whole-brain radiotherapy in treating brain metastases based on a systematic review of randomized controlled trials.
    Anti-cancer drugs, 2016, Volume: 27, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Humans;

2016
An Update on the Role of Immunotherapy and Vaccine Strategies for Primary Brain Tumors.
    Current treatment options in oncology, 2015, Volume: 16, Issue:11

    Topics: Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Cancer Vaccines; Combined Modality

2015
An Update on the Role of Immunotherapy and Vaccine Strategies for Primary Brain Tumors.
    Current treatment options in oncology, 2015, Volume: 16, Issue:11

    Topics: Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Cancer Vaccines; Combined Modality

2015
An Update on the Role of Immunotherapy and Vaccine Strategies for Primary Brain Tumors.
    Current treatment options in oncology, 2015, Volume: 16, Issue:11

    Topics: Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Cancer Vaccines; Combined Modality

2015
Procarbazine, lomustine and vincristine or temozolomide: which is the better regimen?
    CNS oncology, 2015, Volume: 4, Issue:5

    Topics: Antineoplastic Agents; Brain Neoplasms; Clinical Trials as Topic; Dacarbazine; Humans; Lomustine; Ol

2015
Procarbazine, lomustine and vincristine or temozolomide: which is the better regimen?
    CNS oncology, 2015, Volume: 4, Issue:5

    Topics: Antineoplastic Agents; Brain Neoplasms; Clinical Trials as Topic; Dacarbazine; Humans; Lomustine; Ol

2015
Procarbazine, lomustine and vincristine or temozolomide: which is the better regimen?
    CNS oncology, 2015, Volume: 4, Issue:5

    Topics: Antineoplastic Agents; Brain Neoplasms; Clinical Trials as Topic; Dacarbazine; Humans; Lomustine; Ol

2015
Guidelines, "minimal requirements" and standard of care in glioblastoma around the Mediterranean Area: A report from the AROME (Association of Radiotherapy and Oncology of the Mediterranean arEa) Neuro-Oncology working party.
    Critical reviews in oncology/hematology, 2016, Volume: 98

    Topics: Adult; Africa, Northern; Brain Neoplasms; Dacarbazine; Glioblastoma; Humans; Medical Oncology; Medit

2016
Guidelines, "minimal requirements" and standard of care in glioblastoma around the Mediterranean Area: A report from the AROME (Association of Radiotherapy and Oncology of the Mediterranean arEa) Neuro-Oncology working party.
    Critical reviews in oncology/hematology, 2016, Volume: 98

    Topics: Adult; Africa, Northern; Brain Neoplasms; Dacarbazine; Glioblastoma; Humans; Medical Oncology; Medit

2016
Guidelines, "minimal requirements" and standard of care in glioblastoma around the Mediterranean Area: A report from the AROME (Association of Radiotherapy and Oncology of the Mediterranean arEa) Neuro-Oncology working party.
    Critical reviews in oncology/hematology, 2016, Volume: 98

    Topics: Adult; Africa, Northern; Brain Neoplasms; Dacarbazine; Glioblastoma; Humans; Medical Oncology; Medit

2016
How I treat glioblastoma in older patients.
    Journal of geriatric oncology, 2016, Volume: 7, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Anticonvulsants; Antineoplastic Agents, Alkylating; Biomarkers, Tumo

2016
How I treat glioblastoma in older patients.
    Journal of geriatric oncology, 2016, Volume: 7, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Anticonvulsants; Antineoplastic Agents, Alkylating; Biomarkers, Tumo

2016
How I treat glioblastoma in older patients.
    Journal of geriatric oncology, 2016, Volume: 7, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Anticonvulsants; Antineoplastic Agents, Alkylating; Biomarkers, Tumo

2016
Targeting autophagy to sensitive glioma to temozolomide treatment.
    Journal of experimental & clinical cancer research : CR, 2016, Feb-02, Volume: 35

    Topics: Antineoplastic Combined Chemotherapy Protocols; Autophagy; Brain Neoplasms; Cell Line, Tumor; Cell S

2016
Targeting autophagy to sensitive glioma to temozolomide treatment.
    Journal of experimental & clinical cancer research : CR, 2016, Feb-02, Volume: 35

    Topics: Antineoplastic Combined Chemotherapy Protocols; Autophagy; Brain Neoplasms; Cell Line, Tumor; Cell S

2016
Targeting autophagy to sensitive glioma to temozolomide treatment.
    Journal of experimental & clinical cancer research : CR, 2016, Feb-02, Volume: 35

    Topics: Antineoplastic Combined Chemotherapy Protocols; Autophagy; Brain Neoplasms; Cell Line, Tumor; Cell S

2016
Therapeutic interactions of autophagy with radiation and temozolomide in glioblastoma: evidence and issues to resolve.
    British journal of cancer, 2016, Mar-01, Volume: 114, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Apoptosis; Autophagy; Brain Neoplasms; Dacarbazine; Glioblastoma;

2016
Therapeutic interactions of autophagy with radiation and temozolomide in glioblastoma: evidence and issues to resolve.
    British journal of cancer, 2016, Mar-01, Volume: 114, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Apoptosis; Autophagy; Brain Neoplasms; Dacarbazine; Glioblastoma;

2016
Therapeutic interactions of autophagy with radiation and temozolomide in glioblastoma: evidence and issues to resolve.
    British journal of cancer, 2016, Mar-01, Volume: 114, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Apoptosis; Autophagy; Brain Neoplasms; Dacarbazine; Glioblastoma;

2016
Brain Radiotherapy plus Concurrent Temozolomide versus Radiotherapy Alone for Patients with Brain Metastases: A Meta-Analysis.
    PloS one, 2016, Volume: 11, Issue:3

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Humans;

2016
Brain Radiotherapy plus Concurrent Temozolomide versus Radiotherapy Alone for Patients with Brain Metastases: A Meta-Analysis.
    PloS one, 2016, Volume: 11, Issue:3

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Humans;

2016
Brain Radiotherapy plus Concurrent Temozolomide versus Radiotherapy Alone for Patients with Brain Metastases: A Meta-Analysis.
    PloS one, 2016, Volume: 11, Issue:3

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Humans;

2016
Low-grade and anaplastic oligodendroglioma.
    Handbook of clinical neurology, 2016, Volume: 134

    Topics: Antineoplastic Agents; Brain Neoplasms; Chemotherapy, Adjuvant; Dacarbazine; DNA Modification Methyl

2016
Low-grade and anaplastic oligodendroglioma.
    Handbook of clinical neurology, 2016, Volume: 134

    Topics: Antineoplastic Agents; Brain Neoplasms; Chemotherapy, Adjuvant; Dacarbazine; DNA Modification Methyl

2016
Low-grade and anaplastic oligodendroglioma.
    Handbook of clinical neurology, 2016, Volume: 134

    Topics: Antineoplastic Agents; Brain Neoplasms; Chemotherapy, Adjuvant; Dacarbazine; DNA Modification Methyl

2016
Cytomegalovirus-targeted immunotherapy and glioblastoma: hype or hope?
    Immunotherapy, 2016, Volume: 8, Issue:4

    Topics: Animals; Brain Neoplasms; Cytomegalovirus; Cytomegalovirus Infections; Dacarbazine; Glioblastoma; Hu

2016
Cytomegalovirus-targeted immunotherapy and glioblastoma: hype or hope?
    Immunotherapy, 2016, Volume: 8, Issue:4

    Topics: Animals; Brain Neoplasms; Cytomegalovirus; Cytomegalovirus Infections; Dacarbazine; Glioblastoma; Hu

2016
Cytomegalovirus-targeted immunotherapy and glioblastoma: hype or hope?
    Immunotherapy, 2016, Volume: 8, Issue:4

    Topics: Animals; Brain Neoplasms; Cytomegalovirus; Cytomegalovirus Infections; Dacarbazine; Glioblastoma; Hu

2016
Pharmacotherapies for the treatment of glioblastoma - current evidence and perspectives.
    Expert opinion on pharmacotherapy, 2016, Volume: 17, Issue:9

    Topics: Bevacizumab; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Glioblastoma; Humans; Neovascu

2016
Pharmacotherapies for the treatment of glioblastoma - current evidence and perspectives.
    Expert opinion on pharmacotherapy, 2016, Volume: 17, Issue:9

    Topics: Bevacizumab; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Glioblastoma; Humans; Neovascu

2016
Pharmacotherapies for the treatment of glioblastoma - current evidence and perspectives.
    Expert opinion on pharmacotherapy, 2016, Volume: 17, Issue:9

    Topics: Bevacizumab; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Glioblastoma; Humans; Neovascu

2016
Effects of Temozolomide and Radiotherapy on Brain Metastatic Tumor: A Systematic Review and Meta-Analysis.
    World neurosurgery, 2016, Volume: 92

    Topics: Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms;

2016
Effects of Temozolomide and Radiotherapy on Brain Metastatic Tumor: A Systematic Review and Meta-Analysis.
    World neurosurgery, 2016, Volume: 92

    Topics: Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms;

2016
Effects of Temozolomide and Radiotherapy on Brain Metastatic Tumor: A Systematic Review and Meta-Analysis.
    World neurosurgery, 2016, Volume: 92

    Topics: Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms;

2016
Problems of Glioblastoma Multiforme Drug Resistance.
    Biochemistry. Biokhimiia, 2016, Volume: 81, Issue:2

    Topics: Animals; Antineoplastic Agents, Alkylating; Blood-Brain Barrier; Brain; Brain Neoplasms; Dacarbazine

2016
Problems of Glioblastoma Multiforme Drug Resistance.
    Biochemistry. Biokhimiia, 2016, Volume: 81, Issue:2

    Topics: Animals; Antineoplastic Agents, Alkylating; Blood-Brain Barrier; Brain; Brain Neoplasms; Dacarbazine

2016
Problems of Glioblastoma Multiforme Drug Resistance.
    Biochemistry. Biokhimiia, 2016, Volume: 81, Issue:2

    Topics: Animals; Antineoplastic Agents, Alkylating; Blood-Brain Barrier; Brain; Brain Neoplasms; Dacarbazine

2016
A network meta-analysis: the overall and progression-free survival of glioma patients treated by different chemotherapeutic interventions combined with radiation therapy (RT).
    Oncotarget, 2016, Oct-18, Volume: 7, Issue:42

    Topics: Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Bayes Theorem; Bevacizumab; Brain Neoplasm

2016
A network meta-analysis: the overall and progression-free survival of glioma patients treated by different chemotherapeutic interventions combined with radiation therapy (RT).
    Oncotarget, 2016, Oct-18, Volume: 7, Issue:42

    Topics: Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Bayes Theorem; Bevacizumab; Brain Neoplasm

2016
A network meta-analysis: the overall and progression-free survival of glioma patients treated by different chemotherapeutic interventions combined with radiation therapy (RT).
    Oncotarget, 2016, Oct-18, Volume: 7, Issue:42

    Topics: Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Bayes Theorem; Bevacizumab; Brain Neoplasm

2016
A case of papillary tumor of the pineal region with a long clinical history: molecular characterization and therapeutic consideration with review of the literature.
    Brain tumor pathology, 2016, Volume: 33, Issue:4

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Brain Neoplasms; Combined Modali

2016
A case of papillary tumor of the pineal region with a long clinical history: molecular characterization and therapeutic consideration with review of the literature.
    Brain tumor pathology, 2016, Volume: 33, Issue:4

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Brain Neoplasms; Combined Modali

2016
A case of papillary tumor of the pineal region with a long clinical history: molecular characterization and therapeutic consideration with review of the literature.
    Brain tumor pathology, 2016, Volume: 33, Issue:4

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Brain Neoplasms; Combined Modali

2016
O
    Lung cancer (Amsterdam, Netherlands), 2017, Volume: 107

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Carcinogenesis; Carcinoma, Non-Small-Cell Lung;

2017
O
    Lung cancer (Amsterdam, Netherlands), 2017, Volume: 107

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Carcinogenesis; Carcinoma, Non-Small-Cell Lung;

2017
O
    Lung cancer (Amsterdam, Netherlands), 2017, Volume: 107

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Carcinogenesis; Carcinoma, Non-Small-Cell Lung;

2017
Gliadel wafer implantation combined with standard radiotherapy and concurrent followed by adjuvant temozolomide for treatment of newly diagnosed high-grade glioma: a systematic literature review.
    World journal of surgical oncology, 2016, Aug-24, Volume: 14, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Carmustine; Chemoradiotherapy; Chemotherapy, Adj

2016
Gliadel wafer implantation combined with standard radiotherapy and concurrent followed by adjuvant temozolomide for treatment of newly diagnosed high-grade glioma: a systematic literature review.
    World journal of surgical oncology, 2016, Aug-24, Volume: 14, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Carmustine; Chemoradiotherapy; Chemotherapy, Adj

2016
Gliadel wafer implantation combined with standard radiotherapy and concurrent followed by adjuvant temozolomide for treatment of newly diagnosed high-grade glioma: a systematic literature review.
    World journal of surgical oncology, 2016, Aug-24, Volume: 14, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Carmustine; Chemoradiotherapy; Chemotherapy, Adj

2016
A state-of-the-art review and guidelines for tumor treating fields treatment planning and patient follow-up in glioblastoma.
    CNS oncology, 2017, Volume: 6, Issue:1

    Topics: Algorithms; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazi

2017
A state-of-the-art review and guidelines for tumor treating fields treatment planning and patient follow-up in glioblastoma.
    CNS oncology, 2017, Volume: 6, Issue:1

    Topics: Algorithms; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazi

2017
A state-of-the-art review and guidelines for tumor treating fields treatment planning and patient follow-up in glioblastoma.
    CNS oncology, 2017, Volume: 6, Issue:1

    Topics: Algorithms; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazi

2017
Current management of low-grade gliomas.
    Current opinion in neurology, 2016, Volume: 29, Issue:6

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease-

2016
Current management of low-grade gliomas.
    Current opinion in neurology, 2016, Volume: 29, Issue:6

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease-

2016
Current management of low-grade gliomas.
    Current opinion in neurology, 2016, Volume: 29, Issue:6

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease-

2016
Microglia in Cancer: For Good or for Bad?
    Advances in experimental medicine and biology, 2016, Volume: 949

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Communication; Cytokines; Dacarbazine; ErbB

2016
Microglia in Cancer: For Good or for Bad?
    Advances in experimental medicine and biology, 2016, Volume: 949

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Communication; Cytokines; Dacarbazine; ErbB

2016
Microglia in Cancer: For Good or for Bad?
    Advances in experimental medicine and biology, 2016, Volume: 949

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Communication; Cytokines; Dacarbazine; ErbB

2016
The prognostic value of MGMT promoter status by pyrosequencing assay for glioblastoma patients' survival: a meta-analysis.
    World journal of surgical oncology, 2016, Oct-12, Volume: 14, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Biomarkers, Tumor; Brain Neoplasms; Dacarbazine; Disease-Free Sur

2016
The prognostic value of MGMT promoter status by pyrosequencing assay for glioblastoma patients' survival: a meta-analysis.
    World journal of surgical oncology, 2016, Oct-12, Volume: 14, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Biomarkers, Tumor; Brain Neoplasms; Dacarbazine; Disease-Free Sur

2016
The prognostic value of MGMT promoter status by pyrosequencing assay for glioblastoma patients' survival: a meta-analysis.
    World journal of surgical oncology, 2016, Oct-12, Volume: 14, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Biomarkers, Tumor; Brain Neoplasms; Dacarbazine; Disease-Free Sur

2016
Current and Future Drug Treatments for Glioblastomas.
    Current medicinal chemistry, 2016, Volume: 23, Issue:38

    Topics: Angiogenesis Inhibitors; Anticonvulsants; Antineoplastic Agents, Alkylating; Bevacizumab; Brain Neop

2016
Current and Future Drug Treatments for Glioblastomas.
    Current medicinal chemistry, 2016, Volume: 23, Issue:38

    Topics: Angiogenesis Inhibitors; Anticonvulsants; Antineoplastic Agents, Alkylating; Bevacizumab; Brain Neop

2016
Current and Future Drug Treatments for Glioblastomas.
    Current medicinal chemistry, 2016, Volume: 23, Issue:38

    Topics: Angiogenesis Inhibitors; Anticonvulsants; Antineoplastic Agents, Alkylating; Bevacizumab; Brain Neop

2016
Glioblastoma Secondary to Meningioma: A Case Report and Literature Review.
    World neurosurgery, 2017, Volume: 98

    Topics: Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Glial Fibrillary Acidic Prote

2017
Glioblastoma Secondary to Meningioma: A Case Report and Literature Review.
    World neurosurgery, 2017, Volume: 98

    Topics: Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Glial Fibrillary Acidic Prote

2017
Glioblastoma Secondary to Meningioma: A Case Report and Literature Review.
    World neurosurgery, 2017, Volume: 98

    Topics: Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Glial Fibrillary Acidic Prote

2017
Radiation Therapy for Glioblastoma: American Society of Clinical Oncology Clinical Practice Guideline Endorsement of the American Society for Radiation Oncology Guideline.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2017, Jan-20, Volume: 35, Issue:3

    Topics: Antineoplastic Agents, Alkylating; Biopsy; Brain Neoplasms; Chemoradiotherapy; Consensus; Cranial Ir

2017
Radiation Therapy for Glioblastoma: American Society of Clinical Oncology Clinical Practice Guideline Endorsement of the American Society for Radiation Oncology Guideline.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2017, Jan-20, Volume: 35, Issue:3

    Topics: Antineoplastic Agents, Alkylating; Biopsy; Brain Neoplasms; Chemoradiotherapy; Consensus; Cranial Ir

2017
Radiation Therapy for Glioblastoma: American Society of Clinical Oncology Clinical Practice Guideline Endorsement of the American Society for Radiation Oncology Guideline.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2017, Jan-20, Volume: 35, Issue:3

    Topics: Antineoplastic Agents, Alkylating; Biopsy; Brain Neoplasms; Chemoradiotherapy; Consensus; Cranial Ir

2017
Temozolomide with or without Radiotherapy in Patients with Newly Diagnosed Glioblastoma Multiforme: A Meta-Analysis.
    European neurology, 2017, Volume: 77, Issue:3-4

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbaz

2017
Temozolomide with or without Radiotherapy in Patients with Newly Diagnosed Glioblastoma Multiforme: A Meta-Analysis.
    European neurology, 2017, Volume: 77, Issue:3-4

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbaz

2017
Temozolomide with or without Radiotherapy in Patients with Newly Diagnosed Glioblastoma Multiforme: A Meta-Analysis.
    European neurology, 2017, Volume: 77, Issue:3-4

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbaz

2017
Critical review of the addition of tumor treating fields (TTFields) to the existing standard of care for newly diagnosed glioblastoma patients.
    Critical reviews in oncology/hematology, 2017, Volume: 111

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Disease-Free Survival;

2017
Critical review of the addition of tumor treating fields (TTFields) to the existing standard of care for newly diagnosed glioblastoma patients.
    Critical reviews in oncology/hematology, 2017, Volume: 111

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Disease-Free Survival;

2017
Critical review of the addition of tumor treating fields (TTFields) to the existing standard of care for newly diagnosed glioblastoma patients.
    Critical reviews in oncology/hematology, 2017, Volume: 111

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Disease-Free Survival;

2017
Single vs. combination immunotherapeutic strategies for glioma.
    Expert opinion on biological therapy, 2017, Volume: 17, Issue:5

    Topics: Animals; Brain Neoplasms; Cancer Vaccines; Combined Modality Therapy; Dacarbazine; Genetic Therapy;

2017
Single vs. combination immunotherapeutic strategies for glioma.
    Expert opinion on biological therapy, 2017, Volume: 17, Issue:5

    Topics: Animals; Brain Neoplasms; Cancer Vaccines; Combined Modality Therapy; Dacarbazine; Genetic Therapy;

2017
Single vs. combination immunotherapeutic strategies for glioma.
    Expert opinion on biological therapy, 2017, Volume: 17, Issue:5

    Topics: Animals; Brain Neoplasms; Cancer Vaccines; Combined Modality Therapy; Dacarbazine; Genetic Therapy;

2017
Mechanisms of disease: temozolomide and glioblastoma--look to the future.
    Nature clinical practice. Oncology, 2008, Volume: 5, Issue:8

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant; Clinical Trials as Topic

2008
Mechanisms of disease: temozolomide and glioblastoma--look to the future.
    Nature clinical practice. Oncology, 2008, Volume: 5, Issue:8

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant; Clinical Trials as Topic

2008
Mechanisms of disease: temozolomide and glioblastoma--look to the future.
    Nature clinical practice. Oncology, 2008, Volume: 5, Issue:8

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant; Clinical Trials as Topic

2008
New (alternative) temozolomide regimens for the treatment of glioma.
    Neuro-oncology, 2009, Volume: 11, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Glioma; Humans; O(6)-Methylguanine-

2009
New (alternative) temozolomide regimens for the treatment of glioma.
    Neuro-oncology, 2009, Volume: 11, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Glioma; Humans; O(6)-Methylguanine-

2009
New (alternative) temozolomide regimens for the treatment of glioma.
    Neuro-oncology, 2009, Volume: 11, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Glioma; Humans; O(6)-Methylguanine-

2009
Temozolomide for high grade glioma.
    The Cochrane database of systematic reviews, 2008, Oct-08, Issue:4

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Glioblastoma; Humans; Neoplasm Recu

2008
Temozolomide for high grade glioma.
    The Cochrane database of systematic reviews, 2008, Oct-08, Issue:4

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Glioblastoma; Humans; Neoplasm Recu

2008
Temozolomide for high grade glioma.
    The Cochrane database of systematic reviews, 2008, Oct-08, Issue:4

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Glioblastoma; Humans; Neoplasm Recu

2008
Multiple intracranial melanoma metastases: case report and review of the literature.
    Journal of neuro-oncology, 2009, Volume: 93, Issue:3

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Cranial Irradiation;

2009
Multiple intracranial melanoma metastases: case report and review of the literature.
    Journal of neuro-oncology, 2009, Volume: 93, Issue:3

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Cranial Irradiation;

2009
Multiple intracranial melanoma metastases: case report and review of the literature.
    Journal of neuro-oncology, 2009, Volume: 93, Issue:3

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Cranial Irradiation;

2009
[Association of radiotherapy and chemotherapy-targeted therapies in glioblastomas].
    Bulletin du cancer, 2009, Volume: 96, Issue:3

    Topics: Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic A

2009
[Association of radiotherapy and chemotherapy-targeted therapies in glioblastomas].
    Bulletin du cancer, 2009, Volume: 96, Issue:3

    Topics: Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic A

2009
[Association of radiotherapy and chemotherapy-targeted therapies in glioblastomas].
    Bulletin du cancer, 2009, Volume: 96, Issue:3

    Topics: Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic A

2009
[Predictive molecular pathological testing in the diagnosis of high-grade tumors of glial origin].
    Magyar onkologia, 2009, Volume: 53, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant; Chromosomes, Human, Pair

2009
[Predictive molecular pathological testing in the diagnosis of high-grade tumors of glial origin].
    Magyar onkologia, 2009, Volume: 53, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant; Chromosomes, Human, Pair

2009
[Predictive molecular pathological testing in the diagnosis of high-grade tumors of glial origin].
    Magyar onkologia, 2009, Volume: 53, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant; Chromosomes, Human, Pair

2009
Temozolomide with radiation therapy in high grade brain gliomas: pharmaceuticals considerations and efficacy; a review article.
    Molecules (Basel, Switzerland), 2009, Apr-16, Volume: 14, Issue:4

    Topics: Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neoplasms; Combined Modality Therapy; Dacarbaz

2009
Temozolomide with radiation therapy in high grade brain gliomas: pharmaceuticals considerations and efficacy; a review article.
    Molecules (Basel, Switzerland), 2009, Apr-16, Volume: 14, Issue:4

    Topics: Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neoplasms; Combined Modality Therapy; Dacarbaz

2009
Temozolomide with radiation therapy in high grade brain gliomas: pharmaceuticals considerations and efficacy; a review article.
    Molecules (Basel, Switzerland), 2009, Apr-16, Volume: 14, Issue:4

    Topics: Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neoplasms; Combined Modality Therapy; Dacarbaz

2009
[Prescription guidebook for temozolomide usage in brain tumors].
    Bulletin du cancer, 2009, Volume: 96, Issue:5

    Topics: Age Factors; Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neoplasms; Dacarbazine; Drug Admi

2009
[Prescription guidebook for temozolomide usage in brain tumors].
    Bulletin du cancer, 2009, Volume: 96, Issue:5

    Topics: Age Factors; Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neoplasms; Dacarbazine; Drug Admi

2009
[Prescription guidebook for temozolomide usage in brain tumors].
    Bulletin du cancer, 2009, Volume: 96, Issue:5

    Topics: Age Factors; Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neoplasms; Dacarbazine; Drug Admi

2009
Temozolomide in malignant gliomas: current use and future targets.
    Cancer chemotherapy and pharmacology, 2009, Volume: 64, Issue:4

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Drug Resistance, Neoplasm; Glioma;

2009
Temozolomide in malignant gliomas: current use and future targets.
    Cancer chemotherapy and pharmacology, 2009, Volume: 64, Issue:4

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Drug Resistance, Neoplasm; Glioma;

2009
Temozolomide in malignant gliomas: current use and future targets.
    Cancer chemotherapy and pharmacology, 2009, Volume: 64, Issue:4

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Drug Resistance, Neoplasm; Glioma;

2009
[Clinicopathological diagnosis of gliomas by genotype analysis].
    Brain and nerve = Shinkei kenkyu no shinpo, 2009, Volume: 61, Issue:7

    Topics: Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms;

2009
[Clinicopathological diagnosis of gliomas by genotype analysis].
    Brain and nerve = Shinkei kenkyu no shinpo, 2009, Volume: 61, Issue:7

    Topics: Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms;

2009
[Clinicopathological diagnosis of gliomas by genotype analysis].
    Brain and nerve = Shinkei kenkyu no shinpo, 2009, Volume: 61, Issue:7

    Topics: Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms;

2009
[Treatment of glioma with temozolomide].
    Brain and nerve = Shinkei kenkyu no shinpo, 2009, Volume: 61, Issue:7

    Topics: Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Pro

2009
[Treatment of glioma with temozolomide].
    Brain and nerve = Shinkei kenkyu no shinpo, 2009, Volume: 61, Issue:7

    Topics: Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Pro

2009
[Treatment of glioma with temozolomide].
    Brain and nerve = Shinkei kenkyu no shinpo, 2009, Volume: 61, Issue:7

    Topics: Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Pro

2009
Insights into pharmacotherapy of malignant glioma in adults.
    Expert opinion on pharmacotherapy, 2009, Volume: 10, Issue:14

    Topics: Adult; Aged; Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Ant

2009
Insights into pharmacotherapy of malignant glioma in adults.
    Expert opinion on pharmacotherapy, 2009, Volume: 10, Issue:14

    Topics: Adult; Aged; Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Ant

2009
Insights into pharmacotherapy of malignant glioma in adults.
    Expert opinion on pharmacotherapy, 2009, Volume: 10, Issue:14

    Topics: Adult; Aged; Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Ant

2009
Current treatment strategies for brain metastasis and complications from therapeutic techniques: a review of current literature.
    American journal of clinical oncology, 2010, Volume: 33, Issue:4

    Topics: Blood-Brain Barrier; Brain; Brain Neoplasms; Cognition; Dacarbazine; Humans; Neoplasm Metastasis; Pr

2010
Current treatment strategies for brain metastasis and complications from therapeutic techniques: a review of current literature.
    American journal of clinical oncology, 2010, Volume: 33, Issue:4

    Topics: Blood-Brain Barrier; Brain; Brain Neoplasms; Cognition; Dacarbazine; Humans; Neoplasm Metastasis; Pr

2010
Current treatment strategies for brain metastasis and complications from therapeutic techniques: a review of current literature.
    American journal of clinical oncology, 2010, Volume: 33, Issue:4

    Topics: Blood-Brain Barrier; Brain; Brain Neoplasms; Cognition; Dacarbazine; Humans; Neoplasm Metastasis; Pr

2010
Radiotherapy for metastatic brain tumors.
    International journal of clinical oncology, 2009, Volume: 14, Issue:4

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant; Cognition Disorders; Cra

2009
Radiotherapy for metastatic brain tumors.
    International journal of clinical oncology, 2009, Volume: 14, Issue:4

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant; Cognition Disorders; Cra

2009
Radiotherapy for metastatic brain tumors.
    International journal of clinical oncology, 2009, Volume: 14, Issue:4

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant; Cognition Disorders; Cra

2009
Pseudoprogression and pseudoresponse in the treatment of gliomas.
    Current opinion in neurology, 2009, Volume: 22, Issue:6

    Topics: Antineoplastic Agents; Brain Neoplasms; Dacarbazine; Diagnostic Imaging; Disease Progression; Glioma

2009
Pseudoprogression and pseudoresponse in the treatment of gliomas.
    Current opinion in neurology, 2009, Volume: 22, Issue:6

    Topics: Antineoplastic Agents; Brain Neoplasms; Dacarbazine; Diagnostic Imaging; Disease Progression; Glioma

2009
Pseudoprogression and pseudoresponse in the treatment of gliomas.
    Current opinion in neurology, 2009, Volume: 22, Issue:6

    Topics: Antineoplastic Agents; Brain Neoplasms; Dacarbazine; Diagnostic Imaging; Disease Progression; Glioma

2009
Concomitant or adjuvant temozolomide with whole-brain irradiation for brain metastases: a meta-analysis.
    Anti-cancer drugs, 2010, Volume: 21, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant; Dacarbazine; Humans; Tem

2010
Concomitant or adjuvant temozolomide with whole-brain irradiation for brain metastases: a meta-analysis.
    Anti-cancer drugs, 2010, Volume: 21, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant; Dacarbazine; Humans; Tem

2010
Concomitant or adjuvant temozolomide with whole-brain irradiation for brain metastases: a meta-analysis.
    Anti-cancer drugs, 2010, Volume: 21, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant; Dacarbazine; Humans; Tem

2010
Current developments in the radiotherapy approach to elderly and frail patients with glioblastoma multiforme.
    Expert review of anticancer therapy, 2009, Volume: 9, Issue:11

    Topics: Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant; Combined Modality

2009
Current developments in the radiotherapy approach to elderly and frail patients with glioblastoma multiforme.
    Expert review of anticancer therapy, 2009, Volume: 9, Issue:11

    Topics: Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant; Combined Modality

2009
Current developments in the radiotherapy approach to elderly and frail patients with glioblastoma multiforme.
    Expert review of anticancer therapy, 2009, Volume: 9, Issue:11

    Topics: Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant; Combined Modality

2009
Anti-glioma therapy with temozolomide and status of the DNA-repair gene MGMT.
    Anticancer research, 2009, Volume: 29, Issue:11

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; DNA Repair; Glioblastoma;

2009
Anti-glioma therapy with temozolomide and status of the DNA-repair gene MGMT.
    Anticancer research, 2009, Volume: 29, Issue:11

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; DNA Repair; Glioblastoma;

2009
Anti-glioma therapy with temozolomide and status of the DNA-repair gene MGMT.
    Anticancer research, 2009, Volume: 29, Issue:11

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; DNA Repair; Glioblastoma;

2009
Simultaneous integrated boost intensity-modulated radiotherapy in patients with high-grade gliomas.
    International journal of radiation oncology, biology, physics, 2010, Oct-01, Volume: 78, Issue:2

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neoplasms; Dacarbazine; Female; H

2010
Simultaneous integrated boost intensity-modulated radiotherapy in patients with high-grade gliomas.
    International journal of radiation oncology, biology, physics, 2010, Oct-01, Volume: 78, Issue:2

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neoplasms; Dacarbazine; Female; H

2010
Simultaneous integrated boost intensity-modulated radiotherapy in patients with high-grade gliomas.
    International journal of radiation oncology, biology, physics, 2010, Oct-01, Volume: 78, Issue:2

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neoplasms; Dacarbazine; Female; H

2010
Should biomarkers be used to design personalized medicine for the treatment of glioblastoma?
    Future oncology (London, England), 2010, Volume: 6, Issue:9

    Topics: Antineoplastic Agents; Biomarkers, Tumor; Brain Neoplasms; Clinical Trials as Topic; Dacarbazine; DN

2010
Should biomarkers be used to design personalized medicine for the treatment of glioblastoma?
    Future oncology (London, England), 2010, Volume: 6, Issue:9

    Topics: Antineoplastic Agents; Biomarkers, Tumor; Brain Neoplasms; Clinical Trials as Topic; Dacarbazine; DN

2010
Should biomarkers be used to design personalized medicine for the treatment of glioblastoma?
    Future oncology (London, England), 2010, Volume: 6, Issue:9

    Topics: Antineoplastic Agents; Biomarkers, Tumor; Brain Neoplasms; Clinical Trials as Topic; Dacarbazine; DN

2010
Temozolomide: therapeutic limitations in the treatment of adult high-grade gliomas.
    Expert review of neurotherapeutics, 2010, Volume: 10, Issue:10

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant; Clinical Trials as Topic

2010
Temozolomide: therapeutic limitations in the treatment of adult high-grade gliomas.
    Expert review of neurotherapeutics, 2010, Volume: 10, Issue:10

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant; Clinical Trials as Topic

2010
Temozolomide: therapeutic limitations in the treatment of adult high-grade gliomas.
    Expert review of neurotherapeutics, 2010, Volume: 10, Issue:10

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant; Clinical Trials as Topic

2010
Brain metastasis in melanoma: clinical activity of CTLA-4 antibody therapy.
    Seminars in oncology, 2010, Volume: 37, Issue:5

    Topics: Antibodies, Monoclonal; Antigens, CD; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasm

2010
Brain metastasis in melanoma: clinical activity of CTLA-4 antibody therapy.
    Seminars in oncology, 2010, Volume: 37, Issue:5

    Topics: Antibodies, Monoclonal; Antigens, CD; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasm

2010
Brain metastasis in melanoma: clinical activity of CTLA-4 antibody therapy.
    Seminars in oncology, 2010, Volume: 37, Issue:5

    Topics: Antibodies, Monoclonal; Antigens, CD; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasm

2010
O6-methylguanine DNA methyltransferase gene promoter methylation status in gliomas and its correlation with other molecular alterations: first Indian report with review of challenges for use in customized treatment.
    Neurosurgery, 2010, Volume: 67, Issue:6

    Topics: Adult; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chromosomes, Human, Pair 1; Dacarbazine;

2010
O6-methylguanine DNA methyltransferase gene promoter methylation status in gliomas and its correlation with other molecular alterations: first Indian report with review of challenges for use in customized treatment.
    Neurosurgery, 2010, Volume: 67, Issue:6

    Topics: Adult; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chromosomes, Human, Pair 1; Dacarbazine;

2010
O6-methylguanine DNA methyltransferase gene promoter methylation status in gliomas and its correlation with other molecular alterations: first Indian report with review of challenges for use in customized treatment.
    Neurosurgery, 2010, Volume: 67, Issue:6

    Topics: Adult; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chromosomes, Human, Pair 1; Dacarbazine;

2010
[Drug therapy of patients with recurrent glioblastoma: is there any evidence?].
    Wiener medizinische Wochenschrift (1946), 2011, Volume: 161, Issue:1-2

    Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Antineoplastic Age

2011
[Drug therapy of patients with recurrent glioblastoma: is there any evidence?].
    Wiener medizinische Wochenschrift (1946), 2011, Volume: 161, Issue:1-2

    Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Antineoplastic Age

2011
[Drug therapy of patients with recurrent glioblastoma: is there any evidence?].
    Wiener medizinische Wochenschrift (1946), 2011, Volume: 161, Issue:1-2

    Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Antineoplastic Age

2011
Temozolomide: Expanding its role in brain cancer.
    Drugs of today (Barcelona, Spain : 1998), 2010, Volume: 46, Issue:11

    Topics: Aged; Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Central Nervous System Neoplasms;

2010
Temozolomide: Expanding its role in brain cancer.
    Drugs of today (Barcelona, Spain : 1998), 2010, Volume: 46, Issue:11

    Topics: Aged; Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Central Nervous System Neoplasms;

2010
Temozolomide: Expanding its role in brain cancer.
    Drugs of today (Barcelona, Spain : 1998), 2010, Volume: 46, Issue:11

    Topics: Aged; Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Central Nervous System Neoplasms;

2010
[Pseudoprogression or pseudoresponse: a challenge for the diagnostic imaging in Glioblastoma multiforme].
    Wiener medizinische Wochenschrift (1946), 2011, Volume: 161, Issue:1-2

    Topics: Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic A

2011
[Pseudoprogression or pseudoresponse: a challenge for the diagnostic imaging in Glioblastoma multiforme].
    Wiener medizinische Wochenschrift (1946), 2011, Volume: 161, Issue:1-2

    Topics: Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic A

2011
[Pseudoprogression or pseudoresponse: a challenge for the diagnostic imaging in Glioblastoma multiforme].
    Wiener medizinische Wochenschrift (1946), 2011, Volume: 161, Issue:1-2

    Topics: Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic A

2011
A novel approach to overcome temozolomide resistance in glioma and melanoma: Inactivation of MGMT by gene therapy.
    Biochemical and biophysical research communications, 2011, Mar-18, Volume: 406, Issue:3

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; DNA Modification Methylase

2011
A novel approach to overcome temozolomide resistance in glioma and melanoma: Inactivation of MGMT by gene therapy.
    Biochemical and biophysical research communications, 2011, Mar-18, Volume: 406, Issue:3

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; DNA Modification Methylase

2011
A novel approach to overcome temozolomide resistance in glioma and melanoma: Inactivation of MGMT by gene therapy.
    Biochemical and biophysical research communications, 2011, Mar-18, Volume: 406, Issue:3

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; DNA Modification Methylase

2011
Bevacizumab as a treatment option for radiation-induced cerebral necrosis.
    Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 2011, Volume: 187, Issue:2

    Topics: Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic A

2011
Bevacizumab as a treatment option for radiation-induced cerebral necrosis.
    Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 2011, Volume: 187, Issue:2

    Topics: Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic A

2011
Bevacizumab as a treatment option for radiation-induced cerebral necrosis.
    Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 2011, Volume: 187, Issue:2

    Topics: Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic A

2011
The sequential use of carmustine wafers (Gliadel®) and post-operative radiotherapy with concomitant temozolomide followed by adjuvant temozolomide: a clinical review.
    British journal of neurosurgery, 2011, Volume: 25, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Car

2011
The sequential use of carmustine wafers (Gliadel®) and post-operative radiotherapy with concomitant temozolomide followed by adjuvant temozolomide: a clinical review.
    British journal of neurosurgery, 2011, Volume: 25, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Car

2011
The sequential use of carmustine wafers (Gliadel®) and post-operative radiotherapy with concomitant temozolomide followed by adjuvant temozolomide: a clinical review.
    British journal of neurosurgery, 2011, Volume: 25, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Car

2011
An algorithm for chemotherapy treatment of recurrent glioma patients after temozolomide failure in the general oncology setting.
    Cancer chemotherapy and pharmacology, 2011, Volume: 67, Issue:5

    Topics: Algorithms; Angiogenesis Inhibitors; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chem

2011
An algorithm for chemotherapy treatment of recurrent glioma patients after temozolomide failure in the general oncology setting.
    Cancer chemotherapy and pharmacology, 2011, Volume: 67, Issue:5

    Topics: Algorithms; Angiogenesis Inhibitors; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chem

2011
An algorithm for chemotherapy treatment of recurrent glioma patients after temozolomide failure in the general oncology setting.
    Cancer chemotherapy and pharmacology, 2011, Volume: 67, Issue:5

    Topics: Algorithms; Angiogenesis Inhibitors; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chem

2011
[MGMT analysis in gliomas].
    Bulletin du cancer, 2011, Volume: 98, Issue:3

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; DNA Repair; Glioma; Humans; Neoplas

2011
[MGMT analysis in gliomas].
    Bulletin du cancer, 2011, Volume: 98, Issue:3

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; DNA Repair; Glioma; Humans; Neoplas

2011
[MGMT analysis in gliomas].
    Bulletin du cancer, 2011, Volume: 98, Issue:3

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; DNA Repair; Glioma; Humans; Neoplas

2011
Combining temozolomide with other antitumor drugs and target-based agents in the treatment of brain metastases: an unending quest or chasing a chimera?
    Expert opinion on investigational drugs, 2011, Volume: 20, Issue:7

    Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Blood-Brain Barrier;

2011
Combining temozolomide with other antitumor drugs and target-based agents in the treatment of brain metastases: an unending quest or chasing a chimera?
    Expert opinion on investigational drugs, 2011, Volume: 20, Issue:7

    Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Blood-Brain Barrier;

2011
Combining temozolomide with other antitumor drugs and target-based agents in the treatment of brain metastases: an unending quest or chasing a chimera?
    Expert opinion on investigational drugs, 2011, Volume: 20, Issue:7

    Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Blood-Brain Barrier;

2011
Using different schedules of Temozolomide to treat low grade gliomas: systematic review of their efficacy and toxicity.
    Journal of neuro-oncology, 2011, Volume: 105, Issue:2

    Topics: Adult; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Drug Administration Schedule

2011
Using different schedules of Temozolomide to treat low grade gliomas: systematic review of their efficacy and toxicity.
    Journal of neuro-oncology, 2011, Volume: 105, Issue:2

    Topics: Adult; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Drug Administration Schedule

2011
Using different schedules of Temozolomide to treat low grade gliomas: systematic review of their efficacy and toxicity.
    Journal of neuro-oncology, 2011, Volume: 105, Issue:2

    Topics: Adult; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Drug Administration Schedule

2011
[Glioblastoma in the elderly].
    Revue neurologique, 2011, Volume: 167, Issue:10

    Topics: Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy, Adju

2011
[Glioblastoma in the elderly].
    Revue neurologique, 2011, Volume: 167, Issue:10

    Topics: Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy, Adju

2011
[Glioblastoma in the elderly].
    Revue neurologique, 2011, Volume: 167, Issue:10

    Topics: Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy, Adju

2011
Loco-regional treatments in first-diagnosis glioblastoma: literature review on association between Stupp protocol and Gliadel.
    Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 2011, Volume: 32 Suppl 2

    Topics: Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms;

2011
Loco-regional treatments in first-diagnosis glioblastoma: literature review on association between Stupp protocol and Gliadel.
    Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 2011, Volume: 32 Suppl 2

    Topics: Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms;

2011
Loco-regional treatments in first-diagnosis glioblastoma: literature review on association between Stupp protocol and Gliadel.
    Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 2011, Volume: 32 Suppl 2

    Topics: Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms;

2011
Chemoresistance of glioblastoma cancer stem cells--much more complex than expected.
    Molecular cancer, 2011, Oct-11, Volume: 10

    Topics: Animals; Antigens, CD; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Dacarba

2011
Chemoresistance of glioblastoma cancer stem cells--much more complex than expected.
    Molecular cancer, 2011, Oct-11, Volume: 10

    Topics: Animals; Antigens, CD; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Dacarba

2011
Chemoresistance of glioblastoma cancer stem cells--much more complex than expected.
    Molecular cancer, 2011, Oct-11, Volume: 10

    Topics: Animals; Antigens, CD; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Dacarba

2011
Hypofractionated radiotherapy with or without concurrent temozolomide in elderly patients with glioblastoma multiforme: a review of ten-year single institutional experience.
    Journal of neuro-oncology, 2012, Volume: 107, Issue:2

    Topics: Age Factors; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazin

2012
Hypofractionated radiotherapy with or without concurrent temozolomide in elderly patients with glioblastoma multiforme: a review of ten-year single institutional experience.
    Journal of neuro-oncology, 2012, Volume: 107, Issue:2

    Topics: Age Factors; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazin

2012
Hypofractionated radiotherapy with or without concurrent temozolomide in elderly patients with glioblastoma multiforme: a review of ten-year single institutional experience.
    Journal of neuro-oncology, 2012, Volume: 107, Issue:2

    Topics: Age Factors; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazin

2012
Marked response of gliomatosis cerebri to temozolomide and whole brain radiotherapy.
    Clinical neurology and neurosurgery, 2012, Volume: 114, Issue:4

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Child; Child, Preschool

2012
Marked response of gliomatosis cerebri to temozolomide and whole brain radiotherapy.
    Clinical neurology and neurosurgery, 2012, Volume: 114, Issue:4

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Child; Child, Preschool

2012
Marked response of gliomatosis cerebri to temozolomide and whole brain radiotherapy.
    Clinical neurology and neurosurgery, 2012, Volume: 114, Issue:4

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Child; Child, Preschool

2012
Severe sustained cholestatic hepatitis following temozolomide in a patient with glioblastoma multiforme: case study and review of data from the FDA adverse event reporting system.
    Neuro-oncology, 2012, Volume: 14, Issue:5

    Topics: Adverse Drug Reaction Reporting Systems; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemica

2012
Severe sustained cholestatic hepatitis following temozolomide in a patient with glioblastoma multiforme: case study and review of data from the FDA adverse event reporting system.
    Neuro-oncology, 2012, Volume: 14, Issue:5

    Topics: Adverse Drug Reaction Reporting Systems; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemica

2012
Severe sustained cholestatic hepatitis following temozolomide in a patient with glioblastoma multiforme: case study and review of data from the FDA adverse event reporting system.
    Neuro-oncology, 2012, Volume: 14, Issue:5

    Topics: Adverse Drug Reaction Reporting Systems; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemica

2012
The role of Bcl-2 family proteins in therapy responses of malignant astrocytic gliomas: Bcl2L12 and beyond.
    TheScientificWorldJournal, 2012, Volume: 2012

    Topics: Antineoplastic Agents; Brain Neoplasms; Caspases; Cell Nucleus; Combined Modality Therapy; Dacarbazi

2012
The role of Bcl-2 family proteins in therapy responses of malignant astrocytic gliomas: Bcl2L12 and beyond.
    TheScientificWorldJournal, 2012, Volume: 2012

    Topics: Antineoplastic Agents; Brain Neoplasms; Caspases; Cell Nucleus; Combined Modality Therapy; Dacarbazi

2012
The role of Bcl-2 family proteins in therapy responses of malignant astrocytic gliomas: Bcl2L12 and beyond.
    TheScientificWorldJournal, 2012, Volume: 2012

    Topics: Antineoplastic Agents; Brain Neoplasms; Caspases; Cell Nucleus; Combined Modality Therapy; Dacarbazi

2012
Temozolomide dosing regimens for glioma patients.
    Current neurology and neuroscience reports, 2012, Volume: 12, Issue:3

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Dose-Response Relationship, Drug; G

2012
Temozolomide dosing regimens for glioma patients.
    Current neurology and neuroscience reports, 2012, Volume: 12, Issue:3

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Dose-Response Relationship, Drug; G

2012
Temozolomide dosing regimens for glioma patients.
    Current neurology and neuroscience reports, 2012, Volume: 12, Issue:3

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Dose-Response Relationship, Drug; G

2012
Temozolomide and other potential agents for the treatment of glioblastoma multiforme.
    Neurosurgery clinics of North America, 2012, Volume: 23, Issue:2

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Glioblastoma; Humans; Temozolomide;

2012
Temozolomide and other potential agents for the treatment of glioblastoma multiforme.
    Neurosurgery clinics of North America, 2012, Volume: 23, Issue:2

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Glioblastoma; Humans; Temozolomide;

2012
Temozolomide and other potential agents for the treatment of glioblastoma multiforme.
    Neurosurgery clinics of North America, 2012, Volume: 23, Issue:2

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Glioblastoma; Humans; Temozolomide;

2012
Cellular-based immunotherapies for patients with glioblastoma multiforme.
    Clinical & developmental immunology, 2012, Volume: 2012

    Topics: Aged; Brain Neoplasms; Cancer Vaccines; Cell Extracts; Clinical Trials as Topic; Combined Modality T

2012
Cellular-based immunotherapies for patients with glioblastoma multiforme.
    Clinical & developmental immunology, 2012, Volume: 2012

    Topics: Aged; Brain Neoplasms; Cancer Vaccines; Cell Extracts; Clinical Trials as Topic; Combined Modality T

2012
Cellular-based immunotherapies for patients with glioblastoma multiforme.
    Clinical & developmental immunology, 2012, Volume: 2012

    Topics: Aged; Brain Neoplasms; Cancer Vaccines; Cell Extracts; Clinical Trials as Topic; Combined Modality T

2012
Cerebral ganglioneuroblastoma of adult onset: two patients and a review of the literature.
    Clinical neurology and neurosurgery, 2012, Volume: 114, Issue:6

    Topics: Adult; Age of Onset; Antineoplastic Agents, Alkylating; Brain; Brain Neoplasms; Chemoradiotherapy; C

2012
Cerebral ganglioneuroblastoma of adult onset: two patients and a review of the literature.
    Clinical neurology and neurosurgery, 2012, Volume: 114, Issue:6

    Topics: Adult; Age of Onset; Antineoplastic Agents, Alkylating; Brain; Brain Neoplasms; Chemoradiotherapy; C

2012
Cerebral ganglioneuroblastoma of adult onset: two patients and a review of the literature.
    Clinical neurology and neurosurgery, 2012, Volume: 114, Issue:6

    Topics: Adult; Age of Onset; Antineoplastic Agents, Alkylating; Brain; Brain Neoplasms; Chemoradiotherapy; C

2012
Molecular mechanisms of temozolomide resistance in glioblastoma multiforme.
    Expert review of anticancer therapy, 2012, Volume: 12, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms;

2012
Molecular mechanisms of temozolomide resistance in glioblastoma multiforme.
    Expert review of anticancer therapy, 2012, Volume: 12, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms;

2012
Molecular mechanisms of temozolomide resistance in glioblastoma multiforme.
    Expert review of anticancer therapy, 2012, Volume: 12, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms;

2012
Recent medical management of glioblastoma.
    Advances in experimental medicine and biology, 2012, Volume: 746

    Topics: Antibodies, Monoclonal; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Clinical Tr

2012
Recent medical management of glioblastoma.
    Advances in experimental medicine and biology, 2012, Volume: 746

    Topics: Antibodies, Monoclonal; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Clinical Tr

2012
Recent medical management of glioblastoma.
    Advances in experimental medicine and biology, 2012, Volume: 746

    Topics: Antibodies, Monoclonal; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Clinical Tr

2012
The efficacy of temozolomide for recurrent glioblastoma multiforme.
    European journal of neurology, 2013, Volume: 20, Issue:2

    Topics: Administration, Metronomic; Antineoplastic Agents, Alkylating; Brain Neoplasms; Clinical Trials, Pha

2013
The efficacy of temozolomide for recurrent glioblastoma multiforme.
    European journal of neurology, 2013, Volume: 20, Issue:2

    Topics: Administration, Metronomic; Antineoplastic Agents, Alkylating; Brain Neoplasms; Clinical Trials, Pha

2013
The efficacy of temozolomide for recurrent glioblastoma multiforme.
    European journal of neurology, 2013, Volume: 20, Issue:2

    Topics: Administration, Metronomic; Antineoplastic Agents, Alkylating; Brain Neoplasms; Clinical Trials, Pha

2013
Potential usefulness of radiosensitizers in glioblastoma.
    Neurosurgery clinics of North America, 2012, Volume: 23, Issue:3

    Topics: Angiogenesis Inhibitors; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant;

2012
Potential usefulness of radiosensitizers in glioblastoma.
    Neurosurgery clinics of North America, 2012, Volume: 23, Issue:3

    Topics: Angiogenesis Inhibitors; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant;

2012
Potential usefulness of radiosensitizers in glioblastoma.
    Neurosurgery clinics of North America, 2012, Volume: 23, Issue:3

    Topics: Angiogenesis Inhibitors; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant;

2012
[Brain metastases from breast cancer: prognostic factors and tailored management].
    Bulletin du cancer, 2013, Jan-01, Volume: 100, Issue:1

    Topics: Age Factors; Aged; Aged, 80 and over; Antineoplastic Agents; Brain Neoplasms; Breast Neoplasms; Daca

2013
[Brain metastases from breast cancer: prognostic factors and tailored management].
    Bulletin du cancer, 2013, Jan-01, Volume: 100, Issue:1

    Topics: Age Factors; Aged; Aged, 80 and over; Antineoplastic Agents; Brain Neoplasms; Breast Neoplasms; Daca

2013
[Brain metastases from breast cancer: prognostic factors and tailored management].
    Bulletin du cancer, 2013, Jan-01, Volume: 100, Issue:1

    Topics: Age Factors; Aged; Aged, 80 and over; Antineoplastic Agents; Brain Neoplasms; Breast Neoplasms; Daca

2013
Temozolomide and unusual indications: review of literature.
    Cancer treatment reviews, 2013, Volume: 39, Issue:2

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Humans; Lung Neoplasms; Melanoma; N

2013
Temozolomide and unusual indications: review of literature.
    Cancer treatment reviews, 2013, Volume: 39, Issue:2

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Humans; Lung Neoplasms; Melanoma; N

2013
Temozolomide and unusual indications: review of literature.
    Cancer treatment reviews, 2013, Volume: 39, Issue:2

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Humans; Lung Neoplasms; Melanoma; N

2013
Temozolomide-related idiosyncratic and other uncommon toxicities: a systematic review.
    Anti-cancer drugs, 2012, Volume: 23, Issue:10

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Comb

2012
Temozolomide-related idiosyncratic and other uncommon toxicities: a systematic review.
    Anti-cancer drugs, 2012, Volume: 23, Issue:10

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Comb

2012
Temozolomide-related idiosyncratic and other uncommon toxicities: a systematic review.
    Anti-cancer drugs, 2012, Volume: 23, Issue:10

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Comb

2012
[Therapeutic strategies and systemic treatment of brain melanoma metastases].
    Bulletin du cancer, 2013, Jan-01, Volume: 100, Issue:1

    Topics: Antibodies, Monoclonal; Antineoplastic Agents; Blood-Brain Barrier; Brain Neoplasms; Combined Modali

2013
[Therapeutic strategies and systemic treatment of brain melanoma metastases].
    Bulletin du cancer, 2013, Jan-01, Volume: 100, Issue:1

    Topics: Antibodies, Monoclonal; Antineoplastic Agents; Blood-Brain Barrier; Brain Neoplasms; Combined Modali

2013
[Therapeutic strategies and systemic treatment of brain melanoma metastases].
    Bulletin du cancer, 2013, Jan-01, Volume: 100, Issue:1

    Topics: Antibodies, Monoclonal; Antineoplastic Agents; Blood-Brain Barrier; Brain Neoplasms; Combined Modali

2013
Chemotherapy in low-grade gliomas.
    Current opinion in oncology, 2012, Volume: 24, Issue:6

    Topics: Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Chemoradiotherapy; Clinical Trials

2012
Chemotherapy in low-grade gliomas.
    Current opinion in oncology, 2012, Volume: 24, Issue:6

    Topics: Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Chemoradiotherapy; Clinical Trials

2012
Chemotherapy in low-grade gliomas.
    Current opinion in oncology, 2012, Volume: 24, Issue:6

    Topics: Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Chemoradiotherapy; Clinical Trials

2012
[Use of angioneogenesis inhibitor monoclonal antibody following standard therapy in recurrent or progressive glioblastoma multiforme].
    Magyar onkologia, 2012, Volume: 56, Issue:3

    Topics: Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Antineoplastic Agents, Alkylating; Antin

2012
[Use of angioneogenesis inhibitor monoclonal antibody following standard therapy in recurrent or progressive glioblastoma multiforme].
    Magyar onkologia, 2012, Volume: 56, Issue:3

    Topics: Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Antineoplastic Agents, Alkylating; Antin

2012
[Use of angioneogenesis inhibitor monoclonal antibody following standard therapy in recurrent or progressive glioblastoma multiforme].
    Magyar onkologia, 2012, Volume: 56, Issue:3

    Topics: Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Antineoplastic Agents, Alkylating; Antin

2012
Integrin inhibitor cilengitide for the treatment of glioblastoma: a brief overview of current clinical results.
    Anticancer research, 2012, Volume: 32, Issue:10

    Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Chemoradiotherapy, Adjuvant; Clinical Trials as Top

2012
Integrin inhibitor cilengitide for the treatment of glioblastoma: a brief overview of current clinical results.
    Anticancer research, 2012, Volume: 32, Issue:10

    Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Chemoradiotherapy, Adjuvant; Clinical Trials as Top

2012
Integrin inhibitor cilengitide for the treatment of glioblastoma: a brief overview of current clinical results.
    Anticancer research, 2012, Volume: 32, Issue:10

    Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Chemoradiotherapy, Adjuvant; Clinical Trials as Top

2012
Impact of temozolomide on immune response during malignant glioma chemotherapy.
    Clinical & developmental immunology, 2012, Volume: 2012

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Drug Resistance, Neoplasm;

2012
Impact of temozolomide on immune response during malignant glioma chemotherapy.
    Clinical & developmental immunology, 2012, Volume: 2012

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Drug Resistance, Neoplasm;

2012
Impact of temozolomide on immune response during malignant glioma chemotherapy.
    Clinical & developmental immunology, 2012, Volume: 2012

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Drug Resistance, Neoplasm;

2012
[Adjuvant radiochemotherapy in the elderly affected by glioblastoma: single-institution experience and literature review].
    La Radiologia medica, 2013, Volume: 118, Issue:5

    Topics: Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Biopsy; Brain Neoplasms; Chemoradiothera

2013
[Adjuvant radiochemotherapy in the elderly affected by glioblastoma: single-institution experience and literature review].
    La Radiologia medica, 2013, Volume: 118, Issue:5

    Topics: Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Biopsy; Brain Neoplasms; Chemoradiothera

2013
[Adjuvant radiochemotherapy in the elderly affected by glioblastoma: single-institution experience and literature review].
    La Radiologia medica, 2013, Volume: 118, Issue:5

    Topics: Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Biopsy; Brain Neoplasms; Chemoradiothera

2013
Recent therapeutic advances and insights of recurrent glioblastoma multiforme.
    Frontiers in bioscience (Landmark edition), 2013, 01-01, Volume: 18, Issue:2

    Topics: Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Antigens, Neoplasm; Antineoplastic Agent

2013
Recent therapeutic advances and insights of recurrent glioblastoma multiforme.
    Frontiers in bioscience (Landmark edition), 2013, 01-01, Volume: 18, Issue:2

    Topics: Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Antigens, Neoplasm; Antineoplastic Agent

2013
Recent therapeutic advances and insights of recurrent glioblastoma multiforme.
    Frontiers in bioscience (Landmark edition), 2013, 01-01, Volume: 18, Issue:2

    Topics: Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Antigens, Neoplasm; Antineoplastic Agent

2013
Systematic review and meta-analysis of temozolomide in animal models of glioma: was clinical efficacy predicted?
    British journal of cancer, 2013, Jan-15, Volume: 108, Issue:1

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Disease Models, Animal; Gl

2013
Systematic review and meta-analysis of temozolomide in animal models of glioma: was clinical efficacy predicted?
    British journal of cancer, 2013, Jan-15, Volume: 108, Issue:1

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Disease Models, Animal; Gl

2013
Systematic review and meta-analysis of temozolomide in animal models of glioma: was clinical efficacy predicted?
    British journal of cancer, 2013, Jan-15, Volume: 108, Issue:1

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Disease Models, Animal; Gl

2013
[Whole brain radiation therapy plus temozolomide in the treatment of brain metastases from non small cell lung cancer: a meta-analysis].
    Zhonghua yi xue za zhi, 2012, Dec-04, Volume: 92, Issue:45

    Topics: Brain Neoplasms; Carcinoma, Non-Small-Cell Lung; Combined Modality Therapy; Cranial Irradiation; Dac

2012
[Whole brain radiation therapy plus temozolomide in the treatment of brain metastases from non small cell lung cancer: a meta-analysis].
    Zhonghua yi xue za zhi, 2012, Dec-04, Volume: 92, Issue:45

    Topics: Brain Neoplasms; Carcinoma, Non-Small-Cell Lung; Combined Modality Therapy; Cranial Irradiation; Dac

2012
[Whole brain radiation therapy plus temozolomide in the treatment of brain metastases from non small cell lung cancer: a meta-analysis].
    Zhonghua yi xue za zhi, 2012, Dec-04, Volume: 92, Issue:45

    Topics: Brain Neoplasms; Carcinoma, Non-Small-Cell Lung; Combined Modality Therapy; Cranial Irradiation; Dac

2012
Imaging characteristics of an unusual, high-grade angiocentric glioma: a case report and review of the literature.
    Journal of radiology case reports, 2012, Volume: 6, Issue:10

    Topics: Adolescent; Brain Neoplasms; Combined Modality Therapy; Cranial Nerve Diseases; Dacarbazine; Diagnos

2012
Imaging characteristics of an unusual, high-grade angiocentric glioma: a case report and review of the literature.
    Journal of radiology case reports, 2012, Volume: 6, Issue:10

    Topics: Adolescent; Brain Neoplasms; Combined Modality Therapy; Cranial Nerve Diseases; Dacarbazine; Diagnos

2012
Imaging characteristics of an unusual, high-grade angiocentric glioma: a case report and review of the literature.
    Journal of radiology case reports, 2012, Volume: 6, Issue:10

    Topics: Adolescent; Brain Neoplasms; Combined Modality Therapy; Cranial Nerve Diseases; Dacarbazine; Diagnos

2012
Temozolomide: a novel oral alkylating agent.
    Expert review of anticancer therapy, 2001, Volume: 1, Issue:1

    Topics: Administration, Oral; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Drug Administ

2001
Temozolomide: a novel oral alkylating agent.
    Expert review of anticancer therapy, 2001, Volume: 1, Issue:1

    Topics: Administration, Oral; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Drug Administ

2001
Temozolomide: a novel oral alkylating agent.
    Expert review of anticancer therapy, 2001, Volume: 1, Issue:1

    Topics: Administration, Oral; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Drug Administ

2001
The use of temozolomide in recurrent malignant gliomas.
    Cancer treatment reviews, 2002, Volume: 28, Issue:2

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Clinical Trials as Topic; Dacarbazine; Glioma; H

2002
The use of temozolomide in recurrent malignant gliomas.
    Cancer treatment reviews, 2002, Volume: 28, Issue:2

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Clinical Trials as Topic; Dacarbazine; Glioma; H

2002
The use of temozolomide in recurrent malignant gliomas.
    Cancer treatment reviews, 2002, Volume: 28, Issue:2

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Clinical Trials as Topic; Dacarbazine; Glioma; H

2002
Chemotherapy for the treatment of metastatic brain tumors.
    Expert review of anticancer therapy, 2002, Volume: 2, Issue:5

    Topics: Antineoplastic Agents; Brain Neoplasms; Carboplatin; Clinical Trials as Topic; Dacarbazine; Humans;

2002
Chemotherapy for the treatment of metastatic brain tumors.
    Expert review of anticancer therapy, 2002, Volume: 2, Issue:5

    Topics: Antineoplastic Agents; Brain Neoplasms; Carboplatin; Clinical Trials as Topic; Dacarbazine; Humans;

2002
Chemotherapy for the treatment of metastatic brain tumors.
    Expert review of anticancer therapy, 2002, Volume: 2, Issue:5

    Topics: Antineoplastic Agents; Brain Neoplasms; Carboplatin; Clinical Trials as Topic; Dacarbazine; Humans;

2002
The emerging role of irinotecan (CPT-11) in the treatment of malignant glioma in brain tumors.
    Cancer, 2003, May-01, Volume: 97, Issue:9 Suppl

    Topics: Adult; Animals; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Phytogenic; Antineoplastic

2003
The emerging role of irinotecan (CPT-11) in the treatment of malignant glioma in brain tumors.
    Cancer, 2003, May-01, Volume: 97, Issue:9 Suppl

    Topics: Adult; Animals; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Phytogenic; Antineoplastic

2003
The emerging role of irinotecan (CPT-11) in the treatment of malignant glioma in brain tumors.
    Cancer, 2003, May-01, Volume: 97, Issue:9 Suppl

    Topics: Adult; Animals; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Phytogenic; Antineoplastic

2003
The role of chemotherapy in brain metastases.
    European journal of cancer (Oxford, England : 1990), 2003, Volume: 39, Issue:15

    Topics: Anticonvulsants; Antineoplastic Agents; Blood-Brain Barrier; Brain Neoplasms; Combined Modality Ther

2003
The role of chemotherapy in brain metastases.
    European journal of cancer (Oxford, England : 1990), 2003, Volume: 39, Issue:15

    Topics: Anticonvulsants; Antineoplastic Agents; Blood-Brain Barrier; Brain Neoplasms; Combined Modality Ther

2003
The role of chemotherapy in brain metastases.
    European journal of cancer (Oxford, England : 1990), 2003, Volume: 39, Issue:15

    Topics: Anticonvulsants; Antineoplastic Agents; Blood-Brain Barrier; Brain Neoplasms; Combined Modality Ther

2003
Oligodendroglioma and anaplastic oligodendroglioma: clinical features, treatment, and prognosis.
    Surgical neurology, 2003, Volume: 60, Issue:5

    Topics: Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Chemotherapy, Adjuvant; Dacarbazine

2003
Oligodendroglioma and anaplastic oligodendroglioma: clinical features, treatment, and prognosis.
    Surgical neurology, 2003, Volume: 60, Issue:5

    Topics: Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Chemotherapy, Adjuvant; Dacarbazine

2003
Oligodendroglioma and anaplastic oligodendroglioma: clinical features, treatment, and prognosis.
    Surgical neurology, 2003, Volume: 60, Issue:5

    Topics: Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Chemotherapy, Adjuvant; Dacarbazine

2003
Temozolomide: realizing the promise and potential.
    Current opinion in oncology, 2003, Volume: 15, Issue:6

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Central Nervous System Neoplasms; Dacarbazine; D

2003
Temozolomide: realizing the promise and potential.
    Current opinion in oncology, 2003, Volume: 15, Issue:6

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Central Nervous System Neoplasms; Dacarbazine; D

2003
Temozolomide: realizing the promise and potential.
    Current opinion in oncology, 2003, Volume: 15, Issue:6

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Central Nervous System Neoplasms; Dacarbazine; D

2003
Novel chemotherapeutic agents for the treatment of glioblastoma multiforme.
    Expert opinion on investigational drugs, 2003, Volume: 12, Issue:12

    Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Antineop

2003
Novel chemotherapeutic agents for the treatment of glioblastoma multiforme.
    Expert opinion on investigational drugs, 2003, Volume: 12, Issue:12

    Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Antineop

2003
Novel chemotherapeutic agents for the treatment of glioblastoma multiforme.
    Expert opinion on investigational drugs, 2003, Volume: 12, Issue:12

    Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Antineop

2003
Benefits of adjuvant chemotherapy in high-grade gliomas.
    Seminars in oncology, 2003, Volume: 30, Issue:6 Suppl 19

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant; Dacarbazine; Glioma; Hum

2003
Benefits of adjuvant chemotherapy in high-grade gliomas.
    Seminars in oncology, 2003, Volume: 30, Issue:6 Suppl 19

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant; Dacarbazine; Glioma; Hum

2003
Benefits of adjuvant chemotherapy in high-grade gliomas.
    Seminars in oncology, 2003, Volume: 30, Issue:6 Suppl 19

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant; Dacarbazine; Glioma; Hum

2003
Can chemotherapy replace radiotherapy in low-grade gliomas? Time for randomized studies.
    Seminars in oncology, 2003, Volume: 30, Issue:6 Suppl 19

    Topics: Adult; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Brain Neop

2003
Can chemotherapy replace radiotherapy in low-grade gliomas? Time for randomized studies.
    Seminars in oncology, 2003, Volume: 30, Issue:6 Suppl 19

    Topics: Adult; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Brain Neop

2003
Can chemotherapy replace radiotherapy in low-grade gliomas? Time for randomized studies.
    Seminars in oncology, 2003, Volume: 30, Issue:6 Suppl 19

    Topics: Adult; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Brain Neop

2003
Should radiotherapy be standard therapy for brain tumors in the elderly? Cons.
    Seminars in oncology, 2003, Volume: 30, Issue:6 Suppl 19

    Topics: Age Factors; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Glioma; Humans;

2003
Should radiotherapy be standard therapy for brain tumors in the elderly? Cons.
    Seminars in oncology, 2003, Volume: 30, Issue:6 Suppl 19

    Topics: Age Factors; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Glioma; Humans;

2003
Should radiotherapy be standard therapy for brain tumors in the elderly? Cons.
    Seminars in oncology, 2003, Volume: 30, Issue:6 Suppl 19

    Topics: Age Factors; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Glioma; Humans;

2003
[Therapy of malignant melanoma at the stage of distant metastasis].
    Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete, 2004, Volume: 55, Issue:2

    Topics: Antineoplastic Agents; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Phytogenic; Antineo

2004
[Therapy of malignant melanoma at the stage of distant metastasis].
    Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete, 2004, Volume: 55, Issue:2

    Topics: Antineoplastic Agents; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Phytogenic; Antineo

2004
[Therapy of malignant melanoma at the stage of distant metastasis].
    Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete, 2004, Volume: 55, Issue:2

    Topics: Antineoplastic Agents; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Phytogenic; Antineo

2004
Management of brain metastases in patients with melanoma.
    Current opinion in oncology, 2004, Volume: 16, Issue:2

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Central Nervous System; Chemotherapy, Adjuvant;

2004
Management of brain metastases in patients with melanoma.
    Current opinion in oncology, 2004, Volume: 16, Issue:2

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Central Nervous System; Chemotherapy, Adjuvant;

2004
Management of brain metastases in patients with melanoma.
    Current opinion in oncology, 2004, Volume: 16, Issue:2

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Central Nervous System; Chemotherapy, Adjuvant;

2004
Immediate post-radiotherapy changes in malignant glioma can mimic tumor progression.
    Neurology, 2004, Aug-10, Volume: 63, Issue:3

    Topics: Antineoplastic Combined Chemotherapy Protocols; Artifacts; Astrocytoma; Brain Edema; Brain Neoplasms

2004
Immediate post-radiotherapy changes in malignant glioma can mimic tumor progression.
    Neurology, 2004, Aug-10, Volume: 63, Issue:3

    Topics: Antineoplastic Combined Chemotherapy Protocols; Artifacts; Astrocytoma; Brain Edema; Brain Neoplasms

2004
Immediate post-radiotherapy changes in malignant glioma can mimic tumor progression.
    Neurology, 2004, Aug-10, Volume: 63, Issue:3

    Topics: Antineoplastic Combined Chemotherapy Protocols; Artifacts; Astrocytoma; Brain Edema; Brain Neoplasms

2004
Salvage therapy for primary CNS lymphoma with a combination of rituximab and temozolomide.
    Neurology, 2004, Sep-14, Volume: 63, Issue:5

    Topics: Aged; Antibodies, Monoclonal; Antibodies, Monoclonal, Murine-Derived; Antigens, CD20; Antigens, Neop

2004
Salvage therapy for primary CNS lymphoma with a combination of rituximab and temozolomide.
    Neurology, 2004, Sep-14, Volume: 63, Issue:5

    Topics: Aged; Antibodies, Monoclonal; Antibodies, Monoclonal, Murine-Derived; Antigens, CD20; Antigens, Neop

2004
Salvage therapy for primary CNS lymphoma with a combination of rituximab and temozolomide.
    Neurology, 2004, Sep-14, Volume: 63, Issue:5

    Topics: Aged; Antibodies, Monoclonal; Antibodies, Monoclonal, Murine-Derived; Antigens, CD20; Antigens, Neop

2004
Management of pilocytic astrocytoma with diffuse leptomeningeal spread: two cases and review of the literature.
    Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 2005, Volume: 21, Issue:6

    Topics: Antineoplastic Agents, Alkylating; Arachnoid Cysts; Astrocytoma; Brain Neoplasms; Child; Child, Pres

2005
Management of pilocytic astrocytoma with diffuse leptomeningeal spread: two cases and review of the literature.
    Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 2005, Volume: 21, Issue:6

    Topics: Antineoplastic Agents, Alkylating; Arachnoid Cysts; Astrocytoma; Brain Neoplasms; Child; Child, Pres

2005
Management of pilocytic astrocytoma with diffuse leptomeningeal spread: two cases and review of the literature.
    Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 2005, Volume: 21, Issue:6

    Topics: Antineoplastic Agents, Alkylating; Arachnoid Cysts; Astrocytoma; Brain Neoplasms; Child; Child, Pres

2005
Neuro-oncology: the growing role of chemotherapy in glioma.
    The Lancet. Neurology, 2005, Volume: 4, Issue:1

    Topics: Antineoplastic Agents; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant; D

2005
Neuro-oncology: the growing role of chemotherapy in glioma.
    The Lancet. Neurology, 2005, Volume: 4, Issue:1

    Topics: Antineoplastic Agents; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant; D

2005
Neuro-oncology: the growing role of chemotherapy in glioma.
    The Lancet. Neurology, 2005, Volume: 4, Issue:1

    Topics: Antineoplastic Agents; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant; D

2005
Research news and notes.
    Surgical neurology, 2005, Volume: 63, Issue:1

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Cost-Benefit Analysis; Dac

2005
Research news and notes.
    Surgical neurology, 2005, Volume: 63, Issue:1

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Cost-Benefit Analysis; Dac

2005
Research news and notes.
    Surgical neurology, 2005, Volume: 63, Issue:1

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Cost-Benefit Analysis; Dac

2005
Response of low-grade oligodendroglial tumors to temozolomide.
    Journal of neuro-oncology, 2004, Volume: 70, Issue:3

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chromosomes, Human, Pair 1; Controlled Clinical

2004
Response of low-grade oligodendroglial tumors to temozolomide.
    Journal of neuro-oncology, 2004, Volume: 70, Issue:3

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chromosomes, Human, Pair 1; Controlled Clinical

2004
Response of low-grade oligodendroglial tumors to temozolomide.
    Journal of neuro-oncology, 2004, Volume: 70, Issue:3

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chromosomes, Human, Pair 1; Controlled Clinical

2004
Treatment-related myelodysplastic syndrome after temozolomide for recurrent high-grade glioma.
    Journal of neuro-oncology, 2005, Volume: 71, Issue:3

    Topics: Acute Disease; Adult; Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neoplasms; Chromosomes,

2005
Treatment-related myelodysplastic syndrome after temozolomide for recurrent high-grade glioma.
    Journal of neuro-oncology, 2005, Volume: 71, Issue:3

    Topics: Acute Disease; Adult; Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neoplasms; Chromosomes,

2005
Treatment-related myelodysplastic syndrome after temozolomide for recurrent high-grade glioma.
    Journal of neuro-oncology, 2005, Volume: 71, Issue:3

    Topics: Acute Disease; Adult; Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neoplasms; Chromosomes,

2005
Benefit of temozolomide compared to procarbazine in treatment of glioblastoma multiforme at first relapse: effect on neurological functioning, performance status, and health related quality of life.
    Cancer investigation, 2005, Volume: 23, Issue:2

    Topics: Antineoplastic Agents; Antineoplastic Agents, Alkylating; Brain Neoplasms; Clinical Trials as Topic;

2005
Benefit of temozolomide compared to procarbazine in treatment of glioblastoma multiforme at first relapse: effect on neurological functioning, performance status, and health related quality of life.
    Cancer investigation, 2005, Volume: 23, Issue:2

    Topics: Antineoplastic Agents; Antineoplastic Agents, Alkylating; Brain Neoplasms; Clinical Trials as Topic;

2005
Benefit of temozolomide compared to procarbazine in treatment of glioblastoma multiforme at first relapse: effect on neurological functioning, performance status, and health related quality of life.
    Cancer investigation, 2005, Volume: 23, Issue:2

    Topics: Antineoplastic Agents; Antineoplastic Agents, Alkylating; Brain Neoplasms; Clinical Trials as Topic;

2005
Adjuvant chemotherapy in the treatment of high grade gliomas.
    Cancer treatment reviews, 2005, Volume: 31, Issue:2

    Topics: Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Chemotherapy, Adjuvant; Dacarbazine

2005
Adjuvant chemotherapy in the treatment of high grade gliomas.
    Cancer treatment reviews, 2005, Volume: 31, Issue:2

    Topics: Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Chemotherapy, Adjuvant; Dacarbazine

2005
Adjuvant chemotherapy in the treatment of high grade gliomas.
    Cancer treatment reviews, 2005, Volume: 31, Issue:2

    Topics: Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Chemotherapy, Adjuvant; Dacarbazine

2005
[Highly quality-controlled radiation therapy].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2005, Volume: 32, Issue:4

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Glioblas

2005
[Highly quality-controlled radiation therapy].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2005, Volume: 32, Issue:4

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Glioblas

2005
[Highly quality-controlled radiation therapy].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2005, Volume: 32, Issue:4

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Glioblas

2005
Optimal role of temozolomide in the treatment of malignant gliomas.
    Current neurology and neuroscience reports, 2005, Volume: 5, Issue:3

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Clinical Trials as Topic; Dacarbazine; Drug Admi

2005
Optimal role of temozolomide in the treatment of malignant gliomas.
    Current neurology and neuroscience reports, 2005, Volume: 5, Issue:3

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Clinical Trials as Topic; Dacarbazine; Drug Admi

2005
Optimal role of temozolomide in the treatment of malignant gliomas.
    Current neurology and neuroscience reports, 2005, Volume: 5, Issue:3

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Clinical Trials as Topic; Dacarbazine; Drug Admi

2005
[New place of the chemotherapy in gliomas].
    Bulletin du cancer, 2005, Volume: 92, Issue:4

    Topics: Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neoplasms; Chemotherapy, Adjuvant; Clinical Tr

2005
[New place of the chemotherapy in gliomas].
    Bulletin du cancer, 2005, Volume: 92, Issue:4

    Topics: Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neoplasms; Chemotherapy, Adjuvant; Clinical Tr

2005
[New place of the chemotherapy in gliomas].
    Bulletin du cancer, 2005, Volume: 92, Issue:4

    Topics: Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neoplasms; Chemotherapy, Adjuvant; Clinical Tr

2005
[Radiotherapy for glioblastomas: from radiobiology to concomitant chemotherapy].
    Cancer radiotherapie : journal de la Societe francaise de radiotherapie oncologique, 2005, Volume: 9, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant; Clinical Trials as Topic

2005
[Radiotherapy for glioblastomas: from radiobiology to concomitant chemotherapy].
    Cancer radiotherapie : journal de la Societe francaise de radiotherapie oncologique, 2005, Volume: 9, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant; Clinical Trials as Topic

2005
[Radiotherapy for glioblastomas: from radiobiology to concomitant chemotherapy].
    Cancer radiotherapie : journal de la Societe francaise de radiotherapie oncologique, 2005, Volume: 9, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant; Clinical Trials as Topic

2005
[Role of extracellular matrix degradation enzyme for glioma invasion].
    Nihon rinsho. Japanese journal of clinical medicine, 2005, Volume: 63 Suppl 9

    Topics: ADAM Proteins; Brain Neoplasms; Dacarbazine; Drug Design; Enzyme Inhibitors; Extracellular Matrix; G

2005
[Role of extracellular matrix degradation enzyme for glioma invasion].
    Nihon rinsho. Japanese journal of clinical medicine, 2005, Volume: 63 Suppl 9

    Topics: ADAM Proteins; Brain Neoplasms; Dacarbazine; Drug Design; Enzyme Inhibitors; Extracellular Matrix; G

2005
[Role of extracellular matrix degradation enzyme for glioma invasion].
    Nihon rinsho. Japanese journal of clinical medicine, 2005, Volume: 63 Suppl 9

    Topics: ADAM Proteins; Brain Neoplasms; Dacarbazine; Drug Design; Enzyme Inhibitors; Extracellular Matrix; G

2005
[Chemotherapy for gliomas in children].
    Nihon rinsho. Japanese journal of clinical medicine, 2005, Volume: 63 Suppl 9

    Topics: Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Astrocytoma; Brai

2005
[Chemotherapy for gliomas in children].
    Nihon rinsho. Japanese journal of clinical medicine, 2005, Volume: 63 Suppl 9

    Topics: Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Astrocytoma; Brai

2005
[Chemotherapy for gliomas in children].
    Nihon rinsho. Japanese journal of clinical medicine, 2005, Volume: 63 Suppl 9

    Topics: Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Astrocytoma; Brai

2005
[Treatment of malignant gliomas in the elderly].
    Nihon rinsho. Japanese journal of clinical medicine, 2005, Volume: 63 Suppl 9

    Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Combined M

2005
[Treatment of malignant gliomas in the elderly].
    Nihon rinsho. Japanese journal of clinical medicine, 2005, Volume: 63 Suppl 9

    Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Combined M

2005
[Treatment of malignant gliomas in the elderly].
    Nihon rinsho. Japanese journal of clinical medicine, 2005, Volume: 63 Suppl 9

    Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Combined M

2005
[Chemotherapy for brain metastases].
    Nihon rinsho. Japanese journal of clinical medicine, 2005, Volume: 63 Suppl 9

    Topics: Anticonvulsants; Antineoplastic Combined Chemotherapy Protocols; Blood-Brain Barrier; Brain Neoplasm

2005
[Chemotherapy for brain metastases].
    Nihon rinsho. Japanese journal of clinical medicine, 2005, Volume: 63 Suppl 9

    Topics: Anticonvulsants; Antineoplastic Combined Chemotherapy Protocols; Blood-Brain Barrier; Brain Neoplasm

2005
[Chemotherapy for brain metastases].
    Nihon rinsho. Japanese journal of clinical medicine, 2005, Volume: 63 Suppl 9

    Topics: Anticonvulsants; Antineoplastic Combined Chemotherapy Protocols; Blood-Brain Barrier; Brain Neoplasm

2005
[Standards and new developments in the chemotherapy of glioblastomas].
    Deutsche medizinische Wochenschrift (1946), 2005, Oct-07, Volume: 130, Issue:40

    Topics: Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms;

2005
[Standards and new developments in the chemotherapy of glioblastomas].
    Deutsche medizinische Wochenschrift (1946), 2005, Oct-07, Volume: 130, Issue:40

    Topics: Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms;

2005
[Standards and new developments in the chemotherapy of glioblastomas].
    Deutsche medizinische Wochenschrift (1946), 2005, Oct-07, Volume: 130, Issue:40

    Topics: Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms;

2005
Treatment of brain metastases: a short review of current therapies and the emerging role of temozolomide.
    Clinical advances in hematology & oncology : H&O, 2003, Volume: 1, Issue:4

    Topics: Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Humans; Radiosurgery; Radiotherapy; Temozol

2003
Treatment of brain metastases: a short review of current therapies and the emerging role of temozolomide.
    Clinical advances in hematology & oncology : H&O, 2003, Volume: 1, Issue:4

    Topics: Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Humans; Radiosurgery; Radiotherapy; Temozol

2003
Treatment of brain metastases: a short review of current therapies and the emerging role of temozolomide.
    Clinical advances in hematology & oncology : H&O, 2003, Volume: 1, Issue:4

    Topics: Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Humans; Radiosurgery; Radiotherapy; Temozol

2003
The role of chemotherapy in the treatment of low-grade glioma. A review of the literature.
    Acta neurologica Belgica, 2005, Volume: 105, Issue:3

    Topics: Antineoplastic Agents; Brain Neoplasms; Clinical Trials as Topic; Dacarbazine; Glioma; Humans; Proca

2005
The role of chemotherapy in the treatment of low-grade glioma. A review of the literature.
    Acta neurologica Belgica, 2005, Volume: 105, Issue:3

    Topics: Antineoplastic Agents; Brain Neoplasms; Clinical Trials as Topic; Dacarbazine; Glioma; Humans; Proca

2005
The role of chemotherapy in the treatment of low-grade glioma. A review of the literature.
    Acta neurologica Belgica, 2005, Volume: 105, Issue:3

    Topics: Antineoplastic Agents; Brain Neoplasms; Clinical Trials as Topic; Dacarbazine; Glioma; Humans; Proca

2005
Treatment of astrocytomas.
    Current opinion in neurology, 2005, Volume: 18, Issue:6

    Topics: Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neoplasms; Dacarbazine; Drug Therapy; Humans;

2005
Treatment of astrocytomas.
    Current opinion in neurology, 2005, Volume: 18, Issue:6

    Topics: Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neoplasms; Dacarbazine; Drug Therapy; Humans;

2005
Treatment of astrocytomas.
    Current opinion in neurology, 2005, Volume: 18, Issue:6

    Topics: Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neoplasms; Dacarbazine; Drug Therapy; Humans;

2005
[Concomitant radiotherapy with chemotherapy in patients with glioblastoma].
    Bulletin du cancer, 2005, Volume: 92, Issue:12

    Topics: Antineoplastic Agents; Brain Neoplasms; Combined Modality Therapy; Cranial Irradiation; Dacarbazine;

2005
[Concomitant radiotherapy with chemotherapy in patients with glioblastoma].
    Bulletin du cancer, 2005, Volume: 92, Issue:12

    Topics: Antineoplastic Agents; Brain Neoplasms; Combined Modality Therapy; Cranial Irradiation; Dacarbazine;

2005
[Concomitant radiotherapy with chemotherapy in patients with glioblastoma].
    Bulletin du cancer, 2005, Volume: 92, Issue:12

    Topics: Antineoplastic Agents; Brain Neoplasms; Combined Modality Therapy; Cranial Irradiation; Dacarbazine;

2005
Recent developments in the use of chemotherapy in brain tumours.
    European journal of cancer (Oxford, England : 1990), 2006, Volume: 42, Issue:5

    Topics: Antineoplastic Agents; Brain Neoplasms; Camptothecin; Dacarbazine; Glioma; Humans; Irinotecan; Temoz

2006
Recent developments in the use of chemotherapy in brain tumours.
    European journal of cancer (Oxford, England : 1990), 2006, Volume: 42, Issue:5

    Topics: Antineoplastic Agents; Brain Neoplasms; Camptothecin; Dacarbazine; Glioma; Humans; Irinotecan; Temoz

2006
Recent developments in the use of chemotherapy in brain tumours.
    European journal of cancer (Oxford, England : 1990), 2006, Volume: 42, Issue:5

    Topics: Antineoplastic Agents; Brain Neoplasms; Camptothecin; Dacarbazine; Glioma; Humans; Irinotecan; Temoz

2006
[Update on cerebral tumors].
    Bulletin du cancer, 2006, Volume: 93, Issue:1

    Topics: Antineoplastic Agents; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy

2006
[Update on cerebral tumors].
    Bulletin du cancer, 2006, Volume: 93, Issue:1

    Topics: Antineoplastic Agents; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy

2006
[Update on cerebral tumors].
    Bulletin du cancer, 2006, Volume: 93, Issue:1

    Topics: Antineoplastic Agents; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy

2006
Advances in the treatment of primary brain tumors: dawn of a new era?
    Current oncology reports, 2006, Volume: 8, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Clinical Trials, Phase III as Topic; Combined Mo

2006
Advances in the treatment of primary brain tumors: dawn of a new era?
    Current oncology reports, 2006, Volume: 8, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Clinical Trials, Phase III as Topic; Combined Mo

2006
Advances in the treatment of primary brain tumors: dawn of a new era?
    Current oncology reports, 2006, Volume: 8, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Clinical Trials, Phase III as Topic; Combined Mo

2006
The evolution of chemoradiation for glioblastoma: a modern success story.
    Current oncology reports, 2006, Volume: 8, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant; Dacarbazine; Female; Gli

2006
The evolution of chemoradiation for glioblastoma: a modern success story.
    Current oncology reports, 2006, Volume: 8, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant; Dacarbazine; Female; Gli

2006
The evolution of chemoradiation for glioblastoma: a modern success story.
    Current oncology reports, 2006, Volume: 8, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant; Dacarbazine; Female; Gli

2006
Temozolomide: a milestone in the pharmacotherapy of brain tumors.
    Future oncology (London, England), 2005, Volume: 1, Issue:6

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Clinical Trials as Topic; Dacarbazine; Humans; T

2005
Temozolomide: a milestone in the pharmacotherapy of brain tumors.
    Future oncology (London, England), 2005, Volume: 1, Issue:6

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Clinical Trials as Topic; Dacarbazine; Humans; T

2005
Temozolomide: a milestone in the pharmacotherapy of brain tumors.
    Future oncology (London, England), 2005, Volume: 1, Issue:6

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Clinical Trials as Topic; Dacarbazine; Humans; T

2005
Role of temozolomide in pediatric brain tumors.
    Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 2006, Volume: 22, Issue:7

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Clinical Trials as Topic; Dacarbazine; Drug Ther

2006
Role of temozolomide in pediatric brain tumors.
    Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 2006, Volume: 22, Issue:7

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Clinical Trials as Topic; Dacarbazine; Drug Ther

2006
Role of temozolomide in pediatric brain tumors.
    Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 2006, Volume: 22, Issue:7

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Clinical Trials as Topic; Dacarbazine; Drug Ther

2006
Treatment options for glioblastoma.
    Neurosurgical focus, 2006, Apr-15, Volume: 20, Issue:4

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Clinical Trials as Topic; Cytotoxins; Dacarbazin

2006
Treatment options for glioblastoma.
    Neurosurgical focus, 2006, Apr-15, Volume: 20, Issue:4

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Clinical Trials as Topic; Cytotoxins; Dacarbazin

2006
Treatment options for glioblastoma.
    Neurosurgical focus, 2006, Apr-15, Volume: 20, Issue:4

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Clinical Trials as Topic; Cytotoxins; Dacarbazin

2006
Autophagy, the Trojan horse to combat glioblastomas.
    Neurosurgical focus, 2006, Apr-15, Volume: 20, Issue:4

    Topics: Antineoplastic Agents, Phytogenic; Autophagy; Brain Neoplasms; Cell Movement; Dacarbazine; Drug Resi

2006
Autophagy, the Trojan horse to combat glioblastomas.
    Neurosurgical focus, 2006, Apr-15, Volume: 20, Issue:4

    Topics: Antineoplastic Agents, Phytogenic; Autophagy; Brain Neoplasms; Cell Movement; Dacarbazine; Drug Resi

2006
Autophagy, the Trojan horse to combat glioblastomas.
    Neurosurgical focus, 2006, Apr-15, Volume: 20, Issue:4

    Topics: Antineoplastic Agents, Phytogenic; Autophagy; Brain Neoplasms; Cell Movement; Dacarbazine; Drug Resi

2006
New trends in the medical management of glioblastoma multiforme: the role of temozolomide chemotherapy.
    Neurosurgical focus, 2006, Apr-15, Volume: 20, Issue:4

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Clinical Trials as Topic; Dacarbazine; DNA Methy

2006
New trends in the medical management of glioblastoma multiforme: the role of temozolomide chemotherapy.
    Neurosurgical focus, 2006, Apr-15, Volume: 20, Issue:4

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Clinical Trials as Topic; Dacarbazine; DNA Methy

2006
New trends in the medical management of glioblastoma multiforme: the role of temozolomide chemotherapy.
    Neurosurgical focus, 2006, Apr-15, Volume: 20, Issue:4

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Clinical Trials as Topic; Dacarbazine; DNA Methy

2006
The role of chemotherapy in the treatment of malignant astrocytomas.
    The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques, 2006, Volume: 33, Issue:2

    Topics: Antineoplastic Agents; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Proto

2006
The role of chemotherapy in the treatment of malignant astrocytomas.
    The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques, 2006, Volume: 33, Issue:2

    Topics: Antineoplastic Agents; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Proto

2006
The role of chemotherapy in the treatment of malignant astrocytomas.
    The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques, 2006, Volume: 33, Issue:2

    Topics: Antineoplastic Agents; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Proto

2006
Radiation therapy in the management of brain metastases from renal cell carcinoma.
    Oncology (Williston Park, N.Y.), 2006, Volume: 20, Issue:6

    Topics: Brain Neoplasms; Carcinoma, Renal Cell; Dacarbazine; Humans; Kidney Neoplasms; Metalloporphyrins; Ne

2006
Radiation therapy in the management of brain metastases from renal cell carcinoma.
    Oncology (Williston Park, N.Y.), 2006, Volume: 20, Issue:6

    Topics: Brain Neoplasms; Carcinoma, Renal Cell; Dacarbazine; Humans; Kidney Neoplasms; Metalloporphyrins; Ne

2006
Radiation therapy in the management of brain metastases from renal cell carcinoma.
    Oncology (Williston Park, N.Y.), 2006, Volume: 20, Issue:6

    Topics: Brain Neoplasms; Carcinoma, Renal Cell; Dacarbazine; Humans; Kidney Neoplasms; Metalloporphyrins; Ne

2006
[Glioma].
    Nihon rinsho. Japanese journal of clinical medicine, 2006, Volume: 64, Issue:7

    Topics: Antineoplastic Agents; Antineoplastic Agents, Alkylating; Brain Neoplasms; Clinical Trials as Topic;

2006
[Glioma].
    Nihon rinsho. Japanese journal of clinical medicine, 2006, Volume: 64, Issue:7

    Topics: Antineoplastic Agents; Antineoplastic Agents, Alkylating; Brain Neoplasms; Clinical Trials as Topic;

2006
[Glioma].
    Nihon rinsho. Japanese journal of clinical medicine, 2006, Volume: 64, Issue:7

    Topics: Antineoplastic Agents; Antineoplastic Agents, Alkylating; Brain Neoplasms; Clinical Trials as Topic;

2006
Temozolomide: a milestone in neuro-oncology and beyond?
    Expert review of anticancer therapy, 2006, Volume: 6, Issue:8

    Topics: Antineoplastic Agents, Alkylating; Base Pair Mismatch; Brain Neoplasms; Clinical Trials, Phase II as

2006
Temozolomide: a milestone in neuro-oncology and beyond?
    Expert review of anticancer therapy, 2006, Volume: 6, Issue:8

    Topics: Antineoplastic Agents, Alkylating; Base Pair Mismatch; Brain Neoplasms; Clinical Trials, Phase II as

2006
Temozolomide: a milestone in neuro-oncology and beyond?
    Expert review of anticancer therapy, 2006, Volume: 6, Issue:8

    Topics: Antineoplastic Agents, Alkylating; Base Pair Mismatch; Brain Neoplasms; Clinical Trials, Phase II as

2006
Drug Insight: temozolomide as a treatment for malignant glioma--impact of a recent trial.
    Nature clinical practice. Neurology, 2005, Volume: 1, Issue:2

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Clinical Trials as Topic; Dacarbazine; DNA Modif

2005
Drug Insight: temozolomide as a treatment for malignant glioma--impact of a recent trial.
    Nature clinical practice. Neurology, 2005, Volume: 1, Issue:2

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Clinical Trials as Topic; Dacarbazine; DNA Modif

2005
Drug Insight: temozolomide as a treatment for malignant glioma--impact of a recent trial.
    Nature clinical practice. Neurology, 2005, Volume: 1, Issue:2

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Clinical Trials as Topic; Dacarbazine; DNA Modif

2005
Chemotherapy for malignant gliomas.
    Wiener medizinische Wochenschrift (1946), 2006, Volume: 156, Issue:11-12

    Topics: Administration, Oral; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant; Cl

2006
Chemotherapy for malignant gliomas.
    Wiener medizinische Wochenschrift (1946), 2006, Volume: 156, Issue:11-12

    Topics: Administration, Oral; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant; Cl

2006
Chemotherapy for malignant gliomas.
    Wiener medizinische Wochenschrift (1946), 2006, Volume: 156, Issue:11-12

    Topics: Administration, Oral; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant; Cl

2006
Should concomitant and adjuvant treatment with temozolomide be used as standard therapy in patients with anaplastic glioma?
    Critical reviews in oncology/hematology, 2006, Volume: 60, Issue:2

    Topics: Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neoplasms; Carcinoma; Chemotherapy, Adjuvant;

2006
Should concomitant and adjuvant treatment with temozolomide be used as standard therapy in patients with anaplastic glioma?
    Critical reviews in oncology/hematology, 2006, Volume: 60, Issue:2

    Topics: Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neoplasms; Carcinoma; Chemotherapy, Adjuvant;

2006
Should concomitant and adjuvant treatment with temozolomide be used as standard therapy in patients with anaplastic glioma?
    Critical reviews in oncology/hematology, 2006, Volume: 60, Issue:2

    Topics: Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neoplasms; Carcinoma; Chemotherapy, Adjuvant;

2006
Glioma therapy in adults.
    The neurologist, 2006, Volume: 12, Issue:6

    Topics: Adult; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Glioma; Humans; Neurosurgica

2006
Glioma therapy in adults.
    The neurologist, 2006, Volume: 12, Issue:6

    Topics: Adult; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Glioma; Humans; Neurosurgica

2006
Glioma therapy in adults.
    The neurologist, 2006, Volume: 12, Issue:6

    Topics: Adult; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Glioma; Humans; Neurosurgica

2006
Oncolytic viruses and DNA-repair machinery: overcoming chemoresistance of gliomas.
    Expert review of anticancer therapy, 2006, Volume: 6, Issue:11

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; DNA Damage; DNA Repair; Drug Resist

2006
Oncolytic viruses and DNA-repair machinery: overcoming chemoresistance of gliomas.
    Expert review of anticancer therapy, 2006, Volume: 6, Issue:11

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; DNA Damage; DNA Repair; Drug Resist

2006
Oncolytic viruses and DNA-repair machinery: overcoming chemoresistance of gliomas.
    Expert review of anticancer therapy, 2006, Volume: 6, Issue:11

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; DNA Damage; DNA Repair; Drug Resist

2006
Temozolomide in advanced malignant melanoma with small brain metastases: can we withhold cranial irradiation?
    Cancer, 2007, Jan-15, Volume: 109, Issue:2

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Clinical Trials, Phase II as Topic;

2007
Temozolomide in advanced malignant melanoma with small brain metastases: can we withhold cranial irradiation?
    Cancer, 2007, Jan-15, Volume: 109, Issue:2

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Clinical Trials, Phase II as Topic;

2007
Temozolomide in advanced malignant melanoma with small brain metastases: can we withhold cranial irradiation?
    Cancer, 2007, Jan-15, Volume: 109, Issue:2

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Clinical Trials, Phase II as Topic;

2007
[Molecular pharmacology on DNA methylating agent temozolomide].
    No shinkei geka. Neurological surgery, 2007, Volume: 35, Issue:2

    Topics: Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cell Division; Dacarbazine; DNA Damag

2007
[Molecular pharmacology on DNA methylating agent temozolomide].
    No shinkei geka. Neurological surgery, 2007, Volume: 35, Issue:2

    Topics: Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cell Division; Dacarbazine; DNA Damag

2007
[Molecular pharmacology on DNA methylating agent temozolomide].
    No shinkei geka. Neurological surgery, 2007, Volume: 35, Issue:2

    Topics: Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cell Division; Dacarbazine; DNA Damag

2007
[Pattern of care of high-grade gliomas].
    La Revue du praticien, 2006, Oct-31, Volume: 56, Issue:16

    Topics: Adrenal Cortex Hormones; Adult; Age Factors; Aged; Anticonvulsants; Antineoplastic Agents, Alkylatin

2006
[Pattern of care of high-grade gliomas].
    La Revue du praticien, 2006, Oct-31, Volume: 56, Issue:16

    Topics: Adrenal Cortex Hormones; Adult; Age Factors; Aged; Anticonvulsants; Antineoplastic Agents, Alkylatin

2006
[Pattern of care of high-grade gliomas].
    La Revue du praticien, 2006, Oct-31, Volume: 56, Issue:16

    Topics: Adrenal Cortex Hormones; Adult; Age Factors; Aged; Anticonvulsants; Antineoplastic Agents, Alkylatin

2006
[What type of adjuvant chemotherapy should be proposed for the initial treatment of glioblastoma?].
    Presse medicale (Paris, France : 1983), 2007, Volume: 36, Issue:9 Pt 2

    Topics: Age Factors; Antineoplastic Agents, Alkylating; Biocompatible Materials; Brain Neoplasms; Carmustine

2007
[What type of adjuvant chemotherapy should be proposed for the initial treatment of glioblastoma?].
    Presse medicale (Paris, France : 1983), 2007, Volume: 36, Issue:9 Pt 2

    Topics: Age Factors; Antineoplastic Agents, Alkylating; Biocompatible Materials; Brain Neoplasms; Carmustine

2007
[What type of adjuvant chemotherapy should be proposed for the initial treatment of glioblastoma?].
    Presse medicale (Paris, France : 1983), 2007, Volume: 36, Issue:9 Pt 2

    Topics: Age Factors; Antineoplastic Agents, Alkylating; Biocompatible Materials; Brain Neoplasms; Carmustine

2007
[Glioma therapy up-date].
    Neurologia (Barcelona, Spain), 2007, Volume: 22, Issue:3

    Topics: Anticoagulants; Anticonvulsants; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemothe

2007
[Glioma therapy up-date].
    Neurologia (Barcelona, Spain), 2007, Volume: 22, Issue:3

    Topics: Anticoagulants; Anticonvulsants; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemothe

2007
[Glioma therapy up-date].
    Neurologia (Barcelona, Spain), 2007, Volume: 22, Issue:3

    Topics: Anticoagulants; Anticonvulsants; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemothe

2007
Anaplastic astrocytoma in adults.
    Critical reviews in oncology/hematology, 2007, Volume: 63, Issue:1

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neoplasms; Clinical T

2007
Anaplastic astrocytoma in adults.
    Critical reviews in oncology/hematology, 2007, Volume: 63, Issue:1

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neoplasms; Clinical T

2007
Anaplastic astrocytoma in adults.
    Critical reviews in oncology/hematology, 2007, Volume: 63, Issue:1

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neoplasms; Clinical T

2007
[Chemotherapy for malignant gliomas].
    No shinkei geka. Neurological surgery, 2007, Volume: 35, Issue:5

    Topics: Antineoplastic Combined Chemotherapy Protocols; Blood-Brain Barrier; Brain Neoplasms; Combined Modal

2007
[Chemotherapy for malignant gliomas].
    No shinkei geka. Neurological surgery, 2007, Volume: 35, Issue:5

    Topics: Antineoplastic Combined Chemotherapy Protocols; Blood-Brain Barrier; Brain Neoplasms; Combined Modal

2007
[Chemotherapy for malignant gliomas].
    No shinkei geka. Neurological surgery, 2007, Volume: 35, Issue:5

    Topics: Antineoplastic Combined Chemotherapy Protocols; Blood-Brain Barrier; Brain Neoplasms; Combined Modal

2007
Prolonged and severe myelosuppression in two patients after low-dose temozolomide treatment- case study and review of literature.
    Journal of neuro-oncology, 2007, Volume: 85, Issue:2

    Topics: Antineoplastic Agents, Alkylating; Bone Marrow; Bone Marrow Diseases; Brain Neoplasms; Cranial Irrad

2007
Prolonged and severe myelosuppression in two patients after low-dose temozolomide treatment- case study and review of literature.
    Journal of neuro-oncology, 2007, Volume: 85, Issue:2

    Topics: Antineoplastic Agents, Alkylating; Bone Marrow; Bone Marrow Diseases; Brain Neoplasms; Cranial Irrad

2007
Prolonged and severe myelosuppression in two patients after low-dose temozolomide treatment- case study and review of literature.
    Journal of neuro-oncology, 2007, Volume: 85, Issue:2

    Topics: Antineoplastic Agents, Alkylating; Bone Marrow; Bone Marrow Diseases; Brain Neoplasms; Cranial Irrad

2007
The economics of temozolomide in brain cancer.
    Expert opinion on pharmacotherapy, 2007, Volume: 8, Issue:12

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Cost-Benefit Analysis

2007
The economics of temozolomide in brain cancer.
    Expert opinion on pharmacotherapy, 2007, Volume: 8, Issue:12

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Cost-Benefit Analysis

2007
The economics of temozolomide in brain cancer.
    Expert opinion on pharmacotherapy, 2007, Volume: 8, Issue:12

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Cost-Benefit Analysis

2007
Potential biochemical therapy of glioma cancer.
    Biochemical and biophysical research communications, 2007, Oct-19, Volume: 362, Issue:2

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Glioma; Humans; Indoles; Models, Bi

2007
Potential biochemical therapy of glioma cancer.
    Biochemical and biophysical research communications, 2007, Oct-19, Volume: 362, Issue:2

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Glioma; Humans; Indoles; Models, Bi

2007
Potential biochemical therapy of glioma cancer.
    Biochemical and biophysical research communications, 2007, Oct-19, Volume: 362, Issue:2

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Glioma; Humans; Indoles; Models, Bi

2007
Molecular targeted therapies and chemotherapy in malignant gliomas.
    Current opinion in oncology, 2007, Volume: 19, Issue:6

    Topics: Antineoplastic Agents; Brain Neoplasms; Clinical Trials as Topic; Dacarbazine; Disease-Free Survival

2007
Molecular targeted therapies and chemotherapy in malignant gliomas.
    Current opinion in oncology, 2007, Volume: 19, Issue:6

    Topics: Antineoplastic Agents; Brain Neoplasms; Clinical Trials as Topic; Dacarbazine; Disease-Free Survival

2007
Molecular targeted therapies and chemotherapy in malignant gliomas.
    Current opinion in oncology, 2007, Volume: 19, Issue:6

    Topics: Antineoplastic Agents; Brain Neoplasms; Clinical Trials as Topic; Dacarbazine; Disease-Free Survival

2007
Temozolomide and radiation in low-grade and anaplastic gliomas: temoradiation.
    Cancer investigation, 2007, Volume: 25, Issue:8

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chromosomes, Human, Pair 1; Chromosomes, Human,

2007
Temozolomide and radiation in low-grade and anaplastic gliomas: temoradiation.
    Cancer investigation, 2007, Volume: 25, Issue:8

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chromosomes, Human, Pair 1; Chromosomes, Human,

2007
Temozolomide and radiation in low-grade and anaplastic gliomas: temoradiation.
    Cancer investigation, 2007, Volume: 25, Issue:8

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chromosomes, Human, Pair 1; Chromosomes, Human,

2007
Diagnosis and treatment of high-grade astrocytoma.
    Neurologic clinics, 2007, Volume: 25, Issue:4

    Topics: Antineoplastic Agents; Astrocytoma; Brachytherapy; Brain Neoplasms; Dacarbazine; Diagnosis, Differen

2007
Diagnosis and treatment of high-grade astrocytoma.
    Neurologic clinics, 2007, Volume: 25, Issue:4

    Topics: Antineoplastic Agents; Astrocytoma; Brachytherapy; Brain Neoplasms; Dacarbazine; Diagnosis, Differen

2007
Diagnosis and treatment of high-grade astrocytoma.
    Neurologic clinics, 2007, Volume: 25, Issue:4

    Topics: Antineoplastic Agents; Astrocytoma; Brachytherapy; Brain Neoplasms; Dacarbazine; Diagnosis, Differen

2007
The effectiveness and cost-effectiveness of carmustine implants and temozolomide for the treatment of newly diagnosed high-grade glioma: a systematic review and economic evaluation.
    Health technology assessment (Winchester, England), 2007, Volume: 11, Issue:45

    Topics: Age Factors; Aged; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols

2007
The effectiveness and cost-effectiveness of carmustine implants and temozolomide for the treatment of newly diagnosed high-grade glioma: a systematic review and economic evaluation.
    Health technology assessment (Winchester, England), 2007, Volume: 11, Issue:45

    Topics: Age Factors; Aged; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols

2007
The effectiveness and cost-effectiveness of carmustine implants and temozolomide for the treatment of newly diagnosed high-grade glioma: a systematic review and economic evaluation.
    Health technology assessment (Winchester, England), 2007, Volume: 11, Issue:45

    Topics: Age Factors; Aged; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols

2007
Management of glioblastoma.
    Expert opinion on pharmacotherapy, 2007, Volume: 8, Issue:18

    Topics: Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms;

2007
Management of glioblastoma.
    Expert opinion on pharmacotherapy, 2007, Volume: 8, Issue:18

    Topics: Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms;

2007
Management of glioblastoma.
    Expert opinion on pharmacotherapy, 2007, Volume: 8, Issue:18

    Topics: Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms;

2007
[Molecular genetic analysis for malignant gliomas: clinical implications and future directions].
    No shinkei geka. Neurological surgery, 2008, Volume: 36, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; DNA Modification Methylases; DNA Re

2008
[Molecular genetic analysis for malignant gliomas: clinical implications and future directions].
    No shinkei geka. Neurological surgery, 2008, Volume: 36, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; DNA Modification Methylases; DNA Re

2008
[Molecular genetic analysis for malignant gliomas: clinical implications and future directions].
    No shinkei geka. Neurological surgery, 2008, Volume: 36, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; DNA Modification Methylases; DNA Re

2008
Overcoming therapeutic resistance in malignant gliomas: current practices and future directions.
    Cancer treatment and research, 2008, Volume: 139

    Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Clinical Trials as Topic; Combined Modality Therapy

2008
Overcoming therapeutic resistance in malignant gliomas: current practices and future directions.
    Cancer treatment and research, 2008, Volume: 139

    Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Clinical Trials as Topic; Combined Modality Therapy

2008
Overcoming therapeutic resistance in malignant gliomas: current practices and future directions.
    Cancer treatment and research, 2008, Volume: 139

    Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Clinical Trials as Topic; Combined Modality Therapy

2008
[Recent advances in chemotherapy for malignant gliomas].
    No shinkei geka. Neurological surgery, 2008, Volume: 36, Issue:2

    Topics: Antineoplastic Agents; Astrocytoma; Brain Neoplasms; Dacarbazine; DNA Repair; Glioma; Humans; Meta-A

2008
[Recent advances in chemotherapy for malignant gliomas].
    No shinkei geka. Neurological surgery, 2008, Volume: 36, Issue:2

    Topics: Antineoplastic Agents; Astrocytoma; Brain Neoplasms; Dacarbazine; DNA Repair; Glioma; Humans; Meta-A

2008
[Recent advances in chemotherapy for malignant gliomas].
    No shinkei geka. Neurological surgery, 2008, Volume: 36, Issue:2

    Topics: Antineoplastic Agents; Astrocytoma; Brain Neoplasms; Dacarbazine; DNA Repair; Glioma; Humans; Meta-A

2008
Carmustine wafers: localized delivery of chemotherapeutic agents in CNS malignancies.
    Expert review of anticancer therapy, 2008, Volume: 8, Issue:3

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Carmustine; Chemotherapy, Adjuvant; Dac

2008
Carmustine wafers: localized delivery of chemotherapeutic agents in CNS malignancies.
    Expert review of anticancer therapy, 2008, Volume: 8, Issue:3

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Carmustine; Chemotherapy, Adjuvant; Dac

2008
Carmustine wafers: localized delivery of chemotherapeutic agents in CNS malignancies.
    Expert review of anticancer therapy, 2008, Volume: 8, Issue:3

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Carmustine; Chemotherapy, Adjuvant; Dac

2008
Combined modality treatment of glioblastoma multiforme: the role of temozolomide.
    Reviews on recent clinical trials, 2006, Volume: 1, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Glioblas

2006
Combined modality treatment of glioblastoma multiforme: the role of temozolomide.
    Reviews on recent clinical trials, 2006, Volume: 1, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Glioblas

2006
Combined modality treatment of glioblastoma multiforme: the role of temozolomide.
    Reviews on recent clinical trials, 2006, Volume: 1, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Glioblas

2006
[Genetic diagnoses and individualized treatment of gliomas].
    No shinkei geka. Neurological surgery, 2008, Volume: 36, Issue:4

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chromosomes, Human, Pair 1; Chromosomes, Human,

2008
[Genetic diagnoses and individualized treatment of gliomas].
    No shinkei geka. Neurological surgery, 2008, Volume: 36, Issue:4

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chromosomes, Human, Pair 1; Chromosomes, Human,

2008
[Genetic diagnoses and individualized treatment of gliomas].
    No shinkei geka. Neurological surgery, 2008, Volume: 36, Issue:4

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chromosomes, Human, Pair 1; Chromosomes, Human,

2008
Clinical features, mechanisms, and management of pseudoprogression in malignant gliomas.
    The Lancet. Oncology, 2008, Volume: 9, Issue:5

    Topics: Acute Disease; Antineoplastic Agents, Alkylating; Apoptosis; Brain Edema; Brain Neoplasms; Chemother

2008
Clinical features, mechanisms, and management of pseudoprogression in malignant gliomas.
    The Lancet. Oncology, 2008, Volume: 9, Issue:5

    Topics: Acute Disease; Antineoplastic Agents, Alkylating; Apoptosis; Brain Edema; Brain Neoplasms; Chemother

2008
Clinical features, mechanisms, and management of pseudoprogression in malignant gliomas.
    The Lancet. Oncology, 2008, Volume: 9, Issue:5

    Topics: Acute Disease; Antineoplastic Agents, Alkylating; Apoptosis; Brain Edema; Brain Neoplasms; Chemother

2008
Current status of clinical trials for glioblastoma.
    Reviews on recent clinical trials, 2006, Volume: 1, Issue:3

    Topics: Antineoplastic Agents; Antineoplastic Agents, Alkylating; Benzamides; Biocompatible Materials; Brain

2006
Current status of clinical trials for glioblastoma.
    Reviews on recent clinical trials, 2006, Volume: 1, Issue:3

    Topics: Antineoplastic Agents; Antineoplastic Agents, Alkylating; Benzamides; Biocompatible Materials; Brain

2006
Current status of clinical trials for glioblastoma.
    Reviews on recent clinical trials, 2006, Volume: 1, Issue:3

    Topics: Antineoplastic Agents; Antineoplastic Agents, Alkylating; Benzamides; Biocompatible Materials; Brain

2006
The therapeutic challenge of gliomas.
    European journal of cancer (Oxford, England : 1990), 1993, Volume: 29A, Issue:7

    Topics: Antineoplastic Agents; Blood-Brain Barrier; Brain Neoplasms; Dacarbazine; Glioma; Humans; Temozolomi

1993
The therapeutic challenge of gliomas.
    European journal of cancer (Oxford, England : 1990), 1993, Volume: 29A, Issue:7

    Topics: Antineoplastic Agents; Blood-Brain Barrier; Brain Neoplasms; Dacarbazine; Glioma; Humans; Temozolomi

1993
The therapeutic challenge of gliomas.
    European journal of cancer (Oxford, England : 1990), 1993, Volume: 29A, Issue:7

    Topics: Antineoplastic Agents; Blood-Brain Barrier; Brain Neoplasms; Dacarbazine; Glioma; Humans; Temozolomi

1993
Systemic treatments for advanced cutaneous melanoma.
    Oncology (Williston Park, N.Y.), 1995, Volume: 9, Issue:11

    Topics: Antibodies, Monoclonal; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Antineoplastic Com

1995
Systemic treatments for advanced cutaneous melanoma.
    Oncology (Williston Park, N.Y.), 1995, Volume: 9, Issue:11

    Topics: Antibodies, Monoclonal; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Antineoplastic Com

1995
Systemic treatments for advanced cutaneous melanoma.
    Oncology (Williston Park, N.Y.), 1995, Volume: 9, Issue:11

    Topics: Antibodies, Monoclonal; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Antineoplastic Com

1995
New chemotherapy options for the treatment of malignant gliomas.
    Current opinion in oncology, 1999, Volume: 11, Issue:3

    Topics: Adult; Antineoplastic Agents; Brain Neoplasms; Camptothecin; Clinical Trials as Topic; Dacarbazine;

1999
New chemotherapy options for the treatment of malignant gliomas.
    Current opinion in oncology, 1999, Volume: 11, Issue:3

    Topics: Adult; Antineoplastic Agents; Brain Neoplasms; Camptothecin; Clinical Trials as Topic; Dacarbazine;

1999
New chemotherapy options for the treatment of malignant gliomas.
    Current opinion in oncology, 1999, Volume: 11, Issue:3

    Topics: Adult; Antineoplastic Agents; Brain Neoplasms; Camptothecin; Clinical Trials as Topic; Dacarbazine;

1999
Temozolomide, a novel alkylating agent with activity in the central nervous system, may improve the treatment of advanced metastatic melanoma.
    The oncologist, 2000, Volume: 5, Issue:2

    Topics: Administration, Oral; Antineoplastic Agents, Alkylating; Biological Availability; Brain Neoplasms; D

2000
Temozolomide, a novel alkylating agent with activity in the central nervous system, may improve the treatment of advanced metastatic melanoma.
    The oncologist, 2000, Volume: 5, Issue:2

    Topics: Administration, Oral; Antineoplastic Agents, Alkylating; Biological Availability; Brain Neoplasms; D

2000
Temozolomide, a novel alkylating agent with activity in the central nervous system, may improve the treatment of advanced metastatic melanoma.
    The oncologist, 2000, Volume: 5, Issue:2

    Topics: Administration, Oral; Antineoplastic Agents, Alkylating; Biological Availability; Brain Neoplasms; D

2000
Temozolomide in malignant gliomas.
    Seminars in oncology, 2000, Volume: 27, Issue:3 Suppl 6

    Topics: Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neoplasms; Clinical Trials as Topic; Dacarbazi

2000
Temozolomide in malignant gliomas.
    Seminars in oncology, 2000, Volume: 27, Issue:3 Suppl 6

    Topics: Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neoplasms; Clinical Trials as Topic; Dacarbazi

2000
Temozolomide in malignant gliomas.
    Seminars in oncology, 2000, Volume: 27, Issue:3 Suppl 6

    Topics: Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neoplasms; Clinical Trials as Topic; Dacarbazi

2000
Temozolomide in early stages of newly diagnosed malignant glioma and neoplastic meningitis.
    Seminars in oncology, 2000, Volume: 27, Issue:3 Suppl 6

    Topics: Animals; Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neoplasms; Clinical Trials as Topic;

2000
Temozolomide in early stages of newly diagnosed malignant glioma and neoplastic meningitis.
    Seminars in oncology, 2000, Volume: 27, Issue:3 Suppl 6

    Topics: Animals; Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neoplasms; Clinical Trials as Topic;

2000
Temozolomide in early stages of newly diagnosed malignant glioma and neoplastic meningitis.
    Seminars in oncology, 2000, Volume: 27, Issue:3 Suppl 6

    Topics: Animals; Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neoplasms; Clinical Trials as Topic;

2000
Future directions in the treatment of malignant gliomas with temozolomide.
    Seminars in oncology, 2000, Volume: 27, Issue:3 Suppl 6

    Topics: Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Biological Availa

2000
Future directions in the treatment of malignant gliomas with temozolomide.
    Seminars in oncology, 2000, Volume: 27, Issue:3 Suppl 6

    Topics: Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Biological Availa

2000
Future directions in the treatment of malignant gliomas with temozolomide.
    Seminars in oncology, 2000, Volume: 27, Issue:3 Suppl 6

    Topics: Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Biological Availa

2000
Temozolomide and treatment of malignant glioma.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2000, Volume: 6, Issue:7

    Topics: Adult; Animals; Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neoplasms; Dacarbazine; Gliobl

2000
Temozolomide and treatment of malignant glioma.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2000, Volume: 6, Issue:7

    Topics: Adult; Animals; Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neoplasms; Dacarbazine; Gliobl

2000
Temozolomide and treatment of malignant glioma.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2000, Volume: 6, Issue:7

    Topics: Adult; Animals; Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neoplasms; Dacarbazine; Gliobl

2000
The effectiveness and cost-effectiveness of temozolomide for the treatment of recurrent malignant glioma: a rapid and systematic review.
    Health technology assessment (Winchester, England), 2001, Volume: 5, Issue:13

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cost-Benefit Analysis; Dacarbazine; Evidence-Bas

2001
The effectiveness and cost-effectiveness of temozolomide for the treatment of recurrent malignant glioma: a rapid and systematic review.
    Health technology assessment (Winchester, England), 2001, Volume: 5, Issue:13

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cost-Benefit Analysis; Dacarbazine; Evidence-Bas

2001
The effectiveness and cost-effectiveness of temozolomide for the treatment of recurrent malignant glioma: a rapid and systematic review.
    Health technology assessment (Winchester, England), 2001, Volume: 5, Issue:13

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cost-Benefit Analysis; Dacarbazine; Evidence-Bas

2001
Atypical teratoid/rhabdoid tumors in adult patients: case report and review of the literature.
    Journal of neuro-oncology, 2001, Volume: 52, Issue:1

    Topics: Adult; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; D

2001
Atypical teratoid/rhabdoid tumors in adult patients: case report and review of the literature.
    Journal of neuro-oncology, 2001, Volume: 52, Issue:1

    Topics: Adult; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; D

2001
Atypical teratoid/rhabdoid tumors in adult patients: case report and review of the literature.
    Journal of neuro-oncology, 2001, Volume: 52, Issue:1

    Topics: Adult; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; D

2001
Temozolomide for treating brain metastases.
    Seminars in oncology, 2001, Volume: 28, Issue:4 Suppl 13

    Topics: Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Carcinoma, Non-Small-Cell Lung; Chemothera

2001
Temozolomide for treating brain metastases.
    Seminars in oncology, 2001, Volume: 28, Issue:4 Suppl 13

    Topics: Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Carcinoma, Non-Small-Cell Lung; Chemothera

2001
Temozolomide for treating brain metastases.
    Seminars in oncology, 2001, Volume: 28, Issue:4 Suppl 13

    Topics: Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Carcinoma, Non-Small-Cell Lung; Chemothera

2001
A rapid and systematic review of the effectiveness of temozolomide for the treatment of recurrent malignant glioma.
    British journal of cancer, 2002, Feb-12, Volume: 86, Issue:4

    Topics: Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neoplasms; Clinical Trials as Topic; Dacarbazi

2002
A rapid and systematic review of the effectiveness of temozolomide for the treatment of recurrent malignant glioma.
    British journal of cancer, 2002, Feb-12, Volume: 86, Issue:4

    Topics: Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neoplasms; Clinical Trials as Topic; Dacarbazi

2002
A rapid and systematic review of the effectiveness of temozolomide for the treatment of recurrent malignant glioma.
    British journal of cancer, 2002, Feb-12, Volume: 86, Issue:4

    Topics: Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neoplasms; Clinical Trials as Topic; Dacarbazi

2002
Current and future developments in the use of temozolomide for the treatment of brain tumours.
    The Lancet. Oncology, 2001, Volume: 2, Issue:9

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Drug Res

2001
Current and future developments in the use of temozolomide for the treatment of brain tumours.
    The Lancet. Oncology, 2001, Volume: 2, Issue:9

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Drug Res

2001
Current and future developments in the use of temozolomide for the treatment of brain tumours.
    The Lancet. Oncology, 2001, Volume: 2, Issue:9

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Drug Res

2001
Adults with newly diagnosed high-grade gliomas.
    Current treatment options in oncology, 2001, Volume: 2, Issue:6

    Topics: Adult; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Antioxidan

2001
Adults with newly diagnosed high-grade gliomas.
    Current treatment options in oncology, 2001, Volume: 2, Issue:6

    Topics: Adult; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Antioxidan

2001
Adults with newly diagnosed high-grade gliomas.
    Current treatment options in oncology, 2001, Volume: 2, Issue:6

    Topics: Adult; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Antioxidan

2001

Trials

513 trials available for temozolomide and Brain Neoplasms

ArticleYear
Safety and efficacy of depatuxizumab mafodotin in Japanese patients with malignant glioma: A nonrandomized, phase 1/2 trial.
    Cancer science, 2021, Volume: 112, Issue:12

    Topics: Adult; Aged; Antibodies, Monoclonal, Humanized; Brain Neoplasms; Chemoradiotherapy; Drug Therapy; Er

2021
Safety and efficacy of depatuxizumab mafodotin in Japanese patients with malignant glioma: A nonrandomized, phase 1/2 trial.
    Cancer science, 2021, Volume: 112, Issue:12

    Topics: Adult; Aged; Antibodies, Monoclonal, Humanized; Brain Neoplasms; Chemoradiotherapy; Drug Therapy; Er

2021
Safety and efficacy of depatuxizumab mafodotin in Japanese patients with malignant glioma: A nonrandomized, phase 1/2 trial.
    Cancer science, 2021, Volume: 112, Issue:12

    Topics: Adult; Aged; Antibodies, Monoclonal, Humanized; Brain Neoplasms; Chemoradiotherapy; Drug Therapy; Er

2021
Afatinib and radiotherapy, with or without temozolomide, in patients with newly diagnosed glioblastoma: results of a phase I trial.
    Journal of neuro-oncology, 2021, Volume: 155, Issue:3

    Topics: Adult; Afatinib; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Dacarbazine; Gliob

2021
Afatinib and radiotherapy, with or without temozolomide, in patients with newly diagnosed glioblastoma: results of a phase I trial.
    Journal of neuro-oncology, 2021, Volume: 155, Issue:3

    Topics: Adult; Afatinib; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Dacarbazine; Gliob

2021
Afatinib and radiotherapy, with or without temozolomide, in patients with newly diagnosed glioblastoma: results of a phase I trial.
    Journal of neuro-oncology, 2021, Volume: 155, Issue:3

    Topics: Adult; Afatinib; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Dacarbazine; Gliob

2021
Chemoradiotherapy with temozolomide vs. radiotherapy alone in patients with IDH wild-type and TERT promoter mutation WHO grade II/III gliomas: A prospective randomized study.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2022, Volume: 167

    Topics: Brain Neoplasms; Chemoradiotherapy; Female; Glioma; Humans; Isocitrate Dehydrogenase; Male; Mutation

2022
Chemoradiotherapy with temozolomide vs. radiotherapy alone in patients with IDH wild-type and TERT promoter mutation WHO grade II/III gliomas: A prospective randomized study.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2022, Volume: 167

    Topics: Brain Neoplasms; Chemoradiotherapy; Female; Glioma; Humans; Isocitrate Dehydrogenase; Male; Mutation

2022
Chemoradiotherapy with temozolomide vs. radiotherapy alone in patients with IDH wild-type and TERT promoter mutation WHO grade II/III gliomas: A prospective randomized study.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2022, Volume: 167

    Topics: Brain Neoplasms; Chemoradiotherapy; Female; Glioma; Humans; Isocitrate Dehydrogenase; Male; Mutation

2022
Safety and tolerability of asunercept plus standard radiotherapy/temozolomide in Asian patients with newly-diagnosed glioblastoma: a phase I study.
    Scientific reports, 2021, 12-15, Volume: 11, Issue:1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Asian People; Biomarkers; Brain Neoplasms; Combined

2021
Safety and tolerability of asunercept plus standard radiotherapy/temozolomide in Asian patients with newly-diagnosed glioblastoma: a phase I study.
    Scientific reports, 2021, 12-15, Volume: 11, Issue:1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Asian People; Biomarkers; Brain Neoplasms; Combined

2021
Safety and tolerability of asunercept plus standard radiotherapy/temozolomide in Asian patients with newly-diagnosed glioblastoma: a phase I study.
    Scientific reports, 2021, 12-15, Volume: 11, Issue:1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Asian People; Biomarkers; Brain Neoplasms; Combined

2021
Treatment of glioblastoma with re-purposed renin-angiotensin system modulators: Results of a phase I clinical trial.
    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2022, Volume: 95

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Glioblastoma; Humans; Quality of Life; Renin-Ang

2022
Treatment of glioblastoma with re-purposed renin-angiotensin system modulators: Results of a phase I clinical trial.
    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2022, Volume: 95

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Glioblastoma; Humans; Quality of Life; Renin-Ang

2022
Treatment of glioblastoma with re-purposed renin-angiotensin system modulators: Results of a phase I clinical trial.
    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2022, Volume: 95

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Glioblastoma; Humans; Quality of Life; Renin-Ang

2022
Temozolomide and Radiotherapy versus Radiotherapy Alone in Patients with Glioblastoma, IDH-wildtype: Post Hoc Analysis of the EORTC Randomized Phase III CATNON Trial.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2022, 06-13, Volume: 28, Issue:12

    Topics: Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neoplasms; Dacarbazine; DNA Methylation; DNA M

2022
Temozolomide and Radiotherapy versus Radiotherapy Alone in Patients with Glioblastoma, IDH-wildtype: Post Hoc Analysis of the EORTC Randomized Phase III CATNON Trial.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2022, 06-13, Volume: 28, Issue:12

    Topics: Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neoplasms; Dacarbazine; DNA Methylation; DNA M

2022
Temozolomide and Radiotherapy versus Radiotherapy Alone in Patients with Glioblastoma, IDH-wildtype: Post Hoc Analysis of the EORTC Randomized Phase III CATNON Trial.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2022, 06-13, Volume: 28, Issue:12

    Topics: Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neoplasms; Dacarbazine; DNA Methylation; DNA M

2022
The efficacy of temozolomide combined with levetiracetam for glioblastoma (GBM) after surgery: a study protocol for a double-blinded and randomized controlled trial.
    Trials, 2022, Mar-28, Volume: 23, Issue:1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Glioblastoma; Humans; Levetiracetam

2022
The efficacy of temozolomide combined with levetiracetam for glioblastoma (GBM) after surgery: a study protocol for a double-blinded and randomized controlled trial.
    Trials, 2022, Mar-28, Volume: 23, Issue:1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Glioblastoma; Humans; Levetiracetam

2022
The efficacy of temozolomide combined with levetiracetam for glioblastoma (GBM) after surgery: a study protocol for a double-blinded and randomized controlled trial.
    Trials, 2022, Mar-28, Volume: 23, Issue:1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Glioblastoma; Humans; Levetiracetam

2022
Radiotherapy combined with nivolumab or temozolomide for newly diagnosed glioblastoma with unmethylated MGMT promoter: An international randomized phase III trial.
    Neuro-oncology, 2023, 01-05, Volume: 25, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Disease-Free Survival; DNA Modification Methylas

2023
Radiotherapy combined with nivolumab or temozolomide for newly diagnosed glioblastoma with unmethylated MGMT promoter: An international randomized phase III trial.
    Neuro-oncology, 2023, 01-05, Volume: 25, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Disease-Free Survival; DNA Modification Methylas

2023
Radiotherapy combined with nivolumab or temozolomide for newly diagnosed glioblastoma with unmethylated MGMT promoter: An international randomized phase III trial.
    Neuro-oncology, 2023, 01-05, Volume: 25, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Disease-Free Survival; DNA Modification Methylas

2023
Phase III trial of chemoradiotherapy with temozolomide plus nivolumab or placebo for newly diagnosed glioblastoma with methylated MGMT promoter.
    Neuro-oncology, 2022, 11-02, Volume: 24, Issue:11

    Topics: Adrenal Cortex Hormones; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; DNA

2022
Phase III trial of chemoradiotherapy with temozolomide plus nivolumab or placebo for newly diagnosed glioblastoma with methylated MGMT promoter.
    Neuro-oncology, 2022, 11-02, Volume: 24, Issue:11

    Topics: Adrenal Cortex Hormones; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; DNA

2022
Phase III trial of chemoradiotherapy with temozolomide plus nivolumab or placebo for newly diagnosed glioblastoma with methylated MGMT promoter.
    Neuro-oncology, 2022, 11-02, Volume: 24, Issue:11

    Topics: Adrenal Cortex Hormones; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; DNA

2022
Temozolomide Treatment Alters Mismatch Repair and Boosts Mutational Burden in Tumor and Blood of Colorectal Cancer Patients.
    Cancer discovery, 2022, 07-06, Volume: 12, Issue:7

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Colorectal Neoplasms; Dacarbaz

2022
Temozolomide Treatment Alters Mismatch Repair and Boosts Mutational Burden in Tumor and Blood of Colorectal Cancer Patients.
    Cancer discovery, 2022, 07-06, Volume: 12, Issue:7

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Colorectal Neoplasms; Dacarbaz

2022
Temozolomide Treatment Alters Mismatch Repair and Boosts Mutational Burden in Tumor and Blood of Colorectal Cancer Patients.
    Cancer discovery, 2022, 07-06, Volume: 12, Issue:7

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Colorectal Neoplasms; Dacarbaz

2022
Prognostic impact of obesity in newly-diagnosed glioblastoma: a secondary analysis of CeTeG/NOA-09 and GLARIUS.
    Journal of neuro-oncology, 2022, Volume: 159, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; DNA Methylation; DNA Modification Methylases; DN

2022
Prognostic impact of obesity in newly-diagnosed glioblastoma: a secondary analysis of CeTeG/NOA-09 and GLARIUS.
    Journal of neuro-oncology, 2022, Volume: 159, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; DNA Methylation; DNA Modification Methylases; DN

2022
Prognostic impact of obesity in newly-diagnosed glioblastoma: a secondary analysis of CeTeG/NOA-09 and GLARIUS.
    Journal of neuro-oncology, 2022, Volume: 159, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; DNA Methylation; DNA Modification Methylases; DN

2022
Cost-Effectiveness Analysis of a Three-Drug Regimen Containing Bevacizumab for the Treatment of Recurrent Pediatric
    Frontiers in public health, 2022, Volume: 10

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Brain Neoplasms; Cerebellar Neoplasms;

2022
Cost-Effectiveness Analysis of a Three-Drug Regimen Containing Bevacizumab for the Treatment of Recurrent Pediatric
    Frontiers in public health, 2022, Volume: 10

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Brain Neoplasms; Cerebellar Neoplasms;

2022
Cost-Effectiveness Analysis of a Three-Drug Regimen Containing Bevacizumab for the Treatment of Recurrent Pediatric
    Frontiers in public health, 2022, Volume: 10

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Brain Neoplasms; Cerebellar Neoplasms;

2022
Depatuxizumab mafodotin in EGFR-amplified newly diagnosed glioblastoma: A phase III randomized clinical trial.
    Neuro-oncology, 2023, 02-14, Volume: 25, Issue:2

    Topics: Adult; Antibodies, Monoclonal, Humanized; Brain Neoplasms; ErbB Receptors; Female; Glioblastoma; Hum

2023
Depatuxizumab mafodotin in EGFR-amplified newly diagnosed glioblastoma: A phase III randomized clinical trial.
    Neuro-oncology, 2023, 02-14, Volume: 25, Issue:2

    Topics: Adult; Antibodies, Monoclonal, Humanized; Brain Neoplasms; ErbB Receptors; Female; Glioblastoma; Hum

2023
Depatuxizumab mafodotin in EGFR-amplified newly diagnosed glioblastoma: A phase III randomized clinical trial.
    Neuro-oncology, 2023, 02-14, Volume: 25, Issue:2

    Topics: Adult; Antibodies, Monoclonal, Humanized; Brain Neoplasms; ErbB Receptors; Female; Glioblastoma; Hum

2023
A Randomized Study of Short Course (One Week) Radiation Therapy with or without Temozolomide in Elderly and/or Frail Patients with Newly Diagnosed Glioblastoma (GBM).
    Asian Pacific journal of cancer prevention : APJCP, 2022, Jul-01, Volume: 23, Issue:7

    Topics: Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Frail Elderly; Glioblastoma; Humans; Quali

2022
A Randomized Study of Short Course (One Week) Radiation Therapy with or without Temozolomide in Elderly and/or Frail Patients with Newly Diagnosed Glioblastoma (GBM).
    Asian Pacific journal of cancer prevention : APJCP, 2022, Jul-01, Volume: 23, Issue:7

    Topics: Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Frail Elderly; Glioblastoma; Humans; Quali

2022
A Randomized Study of Short Course (One Week) Radiation Therapy with or without Temozolomide in Elderly and/or Frail Patients with Newly Diagnosed Glioblastoma (GBM).
    Asian Pacific journal of cancer prevention : APJCP, 2022, Jul-01, Volume: 23, Issue:7

    Topics: Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Frail Elderly; Glioblastoma; Humans; Quali

2022
A phase II open label, single arm study of hypofractionated stereotactic radiotherapy with chemoradiotherapy using intensity-modulated radiotherapy for newly diagnosed glioblastoma after surgery: the HSCK-010 trial protocol.
    BMC cancer, 2022, Jul-29, Volume: 22, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Clinical Trials, Phase II as

2022
A phase II open label, single arm study of hypofractionated stereotactic radiotherapy with chemoradiotherapy using intensity-modulated radiotherapy for newly diagnosed glioblastoma after surgery: the HSCK-010 trial protocol.
    BMC cancer, 2022, Jul-29, Volume: 22, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Clinical Trials, Phase II as

2022
A phase II open label, single arm study of hypofractionated stereotactic radiotherapy with chemoradiotherapy using intensity-modulated radiotherapy for newly diagnosed glioblastoma after surgery: the HSCK-010 trial protocol.
    BMC cancer, 2022, Jul-29, Volume: 22, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Clinical Trials, Phase II as

2022
Granulocyte-macrophage colony stimulating factor enhances efficacy of nimustine rendezvousing with temozolomide plus irradiation in patients with glioblastoma.
    Technology and health care : official journal of the European Society for Engineering and Medicine, 2023, Volume: 31, Issue:2

    Topics: Brain Neoplasms; Glioblastoma; Granulocyte-Macrophage Colony-Stimulating Factor; Granulocytes; Human

2023
Granulocyte-macrophage colony stimulating factor enhances efficacy of nimustine rendezvousing with temozolomide plus irradiation in patients with glioblastoma.
    Technology and health care : official journal of the European Society for Engineering and Medicine, 2023, Volume: 31, Issue:2

    Topics: Brain Neoplasms; Glioblastoma; Granulocyte-Macrophage Colony-Stimulating Factor; Granulocytes; Human

2023
Granulocyte-macrophage colony stimulating factor enhances efficacy of nimustine rendezvousing with temozolomide plus irradiation in patients with glioblastoma.
    Technology and health care : official journal of the European Society for Engineering and Medicine, 2023, Volume: 31, Issue:2

    Topics: Brain Neoplasms; Glioblastoma; Granulocyte-Macrophage Colony-Stimulating Factor; Granulocytes; Human

2023
Concurrent chemoradiation and Tumor Treating Fields (TTFields, 200 kHz) for patients with newly diagnosed glioblastoma: patterns of progression in a single institution pilot study.
    Journal of neuro-oncology, 2022, Volume: 160, Issue:2

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Electric

2022
Concurrent chemoradiation and Tumor Treating Fields (TTFields, 200 kHz) for patients with newly diagnosed glioblastoma: patterns of progression in a single institution pilot study.
    Journal of neuro-oncology, 2022, Volume: 160, Issue:2

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Electric

2022
Concurrent chemoradiation and Tumor Treating Fields (TTFields, 200 kHz) for patients with newly diagnosed glioblastoma: patterns of progression in a single institution pilot study.
    Journal of neuro-oncology, 2022, Volume: 160, Issue:2

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Electric

2022
Preoperative Chemoradiotherapy With Capecitabine With or Without Temozolomide in Patients With Locally Advanced Rectal Cancer: A Prospective, Randomised Phase II Study Stratified by O
    Clinical oncology (Royal College of Radiologists (Great Britain)), 2023, Volume: 35, Issue:2

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Capecitabine; Chemoradiotherapy; Dacarbazine; DN

2023
Preoperative Chemoradiotherapy With Capecitabine With or Without Temozolomide in Patients With Locally Advanced Rectal Cancer: A Prospective, Randomised Phase II Study Stratified by O
    Clinical oncology (Royal College of Radiologists (Great Britain)), 2023, Volume: 35, Issue:2

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Capecitabine; Chemoradiotherapy; Dacarbazine; DN

2023
Preoperative Chemoradiotherapy With Capecitabine With or Without Temozolomide in Patients With Locally Advanced Rectal Cancer: A Prospective, Randomised Phase II Study Stratified by O
    Clinical oncology (Royal College of Radiologists (Great Britain)), 2023, Volume: 35, Issue:2

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Capecitabine; Chemoradiotherapy; Dacarbazine; DN

2023
Association of Autologous Tumor Lysate-Loaded Dendritic Cell Vaccination With Extension of Survival Among Patients With Newly Diagnosed and Recurrent Glioblastoma: A Phase 3 Prospective Externally Controlled Cohort Trial.
    JAMA oncology, 2023, 01-01, Volume: 9, Issue:1

    Topics: Brain Neoplasms; Dendritic Cells; Glioblastoma; Humans; Prospective Studies; Recurrence; Temozolomid

2023
Association of Autologous Tumor Lysate-Loaded Dendritic Cell Vaccination With Extension of Survival Among Patients With Newly Diagnosed and Recurrent Glioblastoma: A Phase 3 Prospective Externally Controlled Cohort Trial.
    JAMA oncology, 2023, 01-01, Volume: 9, Issue:1

    Topics: Brain Neoplasms; Dendritic Cells; Glioblastoma; Humans; Prospective Studies; Recurrence; Temozolomid

2023
Association of Autologous Tumor Lysate-Loaded Dendritic Cell Vaccination With Extension of Survival Among Patients With Newly Diagnosed and Recurrent Glioblastoma: A Phase 3 Prospective Externally Controlled Cohort Trial.
    JAMA oncology, 2023, 01-01, Volume: 9, Issue:1

    Topics: Brain Neoplasms; Dendritic Cells; Glioblastoma; Humans; Prospective Studies; Recurrence; Temozolomid

2023
Association of Autologous Tumor Lysate-Loaded Dendritic Cell Vaccination With Extension of Survival Among Patients With Newly Diagnosed and Recurrent Glioblastoma: A Phase 3 Prospective Externally Controlled Cohort Trial.
    JAMA oncology, 2023, 01-01, Volume: 9, Issue:1

    Topics: Brain Neoplasms; Dendritic Cells; Glioblastoma; Humans; Prospective Studies; Recurrence; Temozolomid

2023
Association of Autologous Tumor Lysate-Loaded Dendritic Cell Vaccination With Extension of Survival Among Patients With Newly Diagnosed and Recurrent Glioblastoma: A Phase 3 Prospective Externally Controlled Cohort Trial.
    JAMA oncology, 2023, 01-01, Volume: 9, Issue:1

    Topics: Brain Neoplasms; Dendritic Cells; Glioblastoma; Humans; Prospective Studies; Recurrence; Temozolomid

2023
Association of Autologous Tumor Lysate-Loaded Dendritic Cell Vaccination With Extension of Survival Among Patients With Newly Diagnosed and Recurrent Glioblastoma: A Phase 3 Prospective Externally Controlled Cohort Trial.
    JAMA oncology, 2023, 01-01, Volume: 9, Issue:1

    Topics: Brain Neoplasms; Dendritic Cells; Glioblastoma; Humans; Prospective Studies; Recurrence; Temozolomid

2023
Association of Autologous Tumor Lysate-Loaded Dendritic Cell Vaccination With Extension of Survival Among Patients With Newly Diagnosed and Recurrent Glioblastoma: A Phase 3 Prospective Externally Controlled Cohort Trial.
    JAMA oncology, 2023, 01-01, Volume: 9, Issue:1

    Topics: Brain Neoplasms; Dendritic Cells; Glioblastoma; Humans; Prospective Studies; Recurrence; Temozolomid

2023
Association of Autologous Tumor Lysate-Loaded Dendritic Cell Vaccination With Extension of Survival Among Patients With Newly Diagnosed and Recurrent Glioblastoma: A Phase 3 Prospective Externally Controlled Cohort Trial.
    JAMA oncology, 2023, 01-01, Volume: 9, Issue:1

    Topics: Brain Neoplasms; Dendritic Cells; Glioblastoma; Humans; Prospective Studies; Recurrence; Temozolomid

2023
Association of Autologous Tumor Lysate-Loaded Dendritic Cell Vaccination With Extension of Survival Among Patients With Newly Diagnosed and Recurrent Glioblastoma: A Phase 3 Prospective Externally Controlled Cohort Trial.
    JAMA oncology, 2023, 01-01, Volume: 9, Issue:1

    Topics: Brain Neoplasms; Dendritic Cells; Glioblastoma; Humans; Prospective Studies; Recurrence; Temozolomid

2023
Association of Autologous Tumor Lysate-Loaded Dendritic Cell Vaccination With Extension of Survival Among Patients With Newly Diagnosed and Recurrent Glioblastoma: A Phase 3 Prospective Externally Controlled Cohort Trial.
    JAMA oncology, 2023, 01-01, Volume: 9, Issue:1

    Topics: Brain Neoplasms; Dendritic Cells; Glioblastoma; Humans; Prospective Studies; Recurrence; Temozolomid

2023
Association of Autologous Tumor Lysate-Loaded Dendritic Cell Vaccination With Extension of Survival Among Patients With Newly Diagnosed and Recurrent Glioblastoma: A Phase 3 Prospective Externally Controlled Cohort Trial.
    JAMA oncology, 2023, 01-01, Volume: 9, Issue:1

    Topics: Brain Neoplasms; Dendritic Cells; Glioblastoma; Humans; Prospective Studies; Recurrence; Temozolomid

2023
Association of Autologous Tumor Lysate-Loaded Dendritic Cell Vaccination With Extension of Survival Among Patients With Newly Diagnosed and Recurrent Glioblastoma: A Phase 3 Prospective Externally Controlled Cohort Trial.
    JAMA oncology, 2023, 01-01, Volume: 9, Issue:1

    Topics: Brain Neoplasms; Dendritic Cells; Glioblastoma; Humans; Prospective Studies; Recurrence; Temozolomid

2023
Association of Autologous Tumor Lysate-Loaded Dendritic Cell Vaccination With Extension of Survival Among Patients With Newly Diagnosed and Recurrent Glioblastoma: A Phase 3 Prospective Externally Controlled Cohort Trial.
    JAMA oncology, 2023, 01-01, Volume: 9, Issue:1

    Topics: Brain Neoplasms; Dendritic Cells; Glioblastoma; Humans; Prospective Studies; Recurrence; Temozolomid

2023
Association of Autologous Tumor Lysate-Loaded Dendritic Cell Vaccination With Extension of Survival Among Patients With Newly Diagnosed and Recurrent Glioblastoma: A Phase 3 Prospective Externally Controlled Cohort Trial.
    JAMA oncology, 2023, 01-01, Volume: 9, Issue:1

    Topics: Brain Neoplasms; Dendritic Cells; Glioblastoma; Humans; Prospective Studies; Recurrence; Temozolomid

2023
Association of Autologous Tumor Lysate-Loaded Dendritic Cell Vaccination With Extension of Survival Among Patients With Newly Diagnosed and Recurrent Glioblastoma: A Phase 3 Prospective Externally Controlled Cohort Trial.
    JAMA oncology, 2023, 01-01, Volume: 9, Issue:1

    Topics: Brain Neoplasms; Dendritic Cells; Glioblastoma; Humans; Prospective Studies; Recurrence; Temozolomid

2023
Association of Autologous Tumor Lysate-Loaded Dendritic Cell Vaccination With Extension of Survival Among Patients With Newly Diagnosed and Recurrent Glioblastoma: A Phase 3 Prospective Externally Controlled Cohort Trial.
    JAMA oncology, 2023, 01-01, Volume: 9, Issue:1

    Topics: Brain Neoplasms; Dendritic Cells; Glioblastoma; Humans; Prospective Studies; Recurrence; Temozolomid

2023
Association of Autologous Tumor Lysate-Loaded Dendritic Cell Vaccination With Extension of Survival Among Patients With Newly Diagnosed and Recurrent Glioblastoma: A Phase 3 Prospective Externally Controlled Cohort Trial.
    JAMA oncology, 2023, 01-01, Volume: 9, Issue:1

    Topics: Brain Neoplasms; Dendritic Cells; Glioblastoma; Humans; Prospective Studies; Recurrence; Temozolomid

2023
Association of Autologous Tumor Lysate-Loaded Dendritic Cell Vaccination With Extension of Survival Among Patients With Newly Diagnosed and Recurrent Glioblastoma: A Phase 3 Prospective Externally Controlled Cohort Trial.
    JAMA oncology, 2023, 01-01, Volume: 9, Issue:1

    Topics: Brain Neoplasms; Dendritic Cells; Glioblastoma; Humans; Prospective Studies; Recurrence; Temozolomid

2023
Association of Autologous Tumor Lysate-Loaded Dendritic Cell Vaccination With Extension of Survival Among Patients With Newly Diagnosed and Recurrent Glioblastoma: A Phase 3 Prospective Externally Controlled Cohort Trial.
    JAMA oncology, 2023, 01-01, Volume: 9, Issue:1

    Topics: Brain Neoplasms; Dendritic Cells; Glioblastoma; Humans; Prospective Studies; Recurrence; Temozolomid

2023
Association of Autologous Tumor Lysate-Loaded Dendritic Cell Vaccination With Extension of Survival Among Patients With Newly Diagnosed and Recurrent Glioblastoma: A Phase 3 Prospective Externally Controlled Cohort Trial.
    JAMA oncology, 2023, 01-01, Volume: 9, Issue:1

    Topics: Brain Neoplasms; Dendritic Cells; Glioblastoma; Humans; Prospective Studies; Recurrence; Temozolomid

2023
Association of Autologous Tumor Lysate-Loaded Dendritic Cell Vaccination With Extension of Survival Among Patients With Newly Diagnosed and Recurrent Glioblastoma: A Phase 3 Prospective Externally Controlled Cohort Trial.
    JAMA oncology, 2023, 01-01, Volume: 9, Issue:1

    Topics: Brain Neoplasms; Dendritic Cells; Glioblastoma; Humans; Prospective Studies; Recurrence; Temozolomid

2023
Association of Autologous Tumor Lysate-Loaded Dendritic Cell Vaccination With Extension of Survival Among Patients With Newly Diagnosed and Recurrent Glioblastoma: A Phase 3 Prospective Externally Controlled Cohort Trial.
    JAMA oncology, 2023, 01-01, Volume: 9, Issue:1

    Topics: Brain Neoplasms; Dendritic Cells; Glioblastoma; Humans; Prospective Studies; Recurrence; Temozolomid

2023
Association of Autologous Tumor Lysate-Loaded Dendritic Cell Vaccination With Extension of Survival Among Patients With Newly Diagnosed and Recurrent Glioblastoma: A Phase 3 Prospective Externally Controlled Cohort Trial.
    JAMA oncology, 2023, 01-01, Volume: 9, Issue:1

    Topics: Brain Neoplasms; Dendritic Cells; Glioblastoma; Humans; Prospective Studies; Recurrence; Temozolomid

2023
Association of Autologous Tumor Lysate-Loaded Dendritic Cell Vaccination With Extension of Survival Among Patients With Newly Diagnosed and Recurrent Glioblastoma: A Phase 3 Prospective Externally Controlled Cohort Trial.
    JAMA oncology, 2023, 01-01, Volume: 9, Issue:1

    Topics: Brain Neoplasms; Dendritic Cells; Glioblastoma; Humans; Prospective Studies; Recurrence; Temozolomid

2023
Association of Autologous Tumor Lysate-Loaded Dendritic Cell Vaccination With Extension of Survival Among Patients With Newly Diagnosed and Recurrent Glioblastoma: A Phase 3 Prospective Externally Controlled Cohort Trial.
    JAMA oncology, 2023, 01-01, Volume: 9, Issue:1

    Topics: Brain Neoplasms; Dendritic Cells; Glioblastoma; Humans; Prospective Studies; Recurrence; Temozolomid

2023
Association of Autologous Tumor Lysate-Loaded Dendritic Cell Vaccination With Extension of Survival Among Patients With Newly Diagnosed and Recurrent Glioblastoma: A Phase 3 Prospective Externally Controlled Cohort Trial.
    JAMA oncology, 2023, 01-01, Volume: 9, Issue:1

    Topics: Brain Neoplasms; Dendritic Cells; Glioblastoma; Humans; Prospective Studies; Recurrence; Temozolomid

2023
Association of Autologous Tumor Lysate-Loaded Dendritic Cell Vaccination With Extension of Survival Among Patients With Newly Diagnosed and Recurrent Glioblastoma: A Phase 3 Prospective Externally Controlled Cohort Trial.
    JAMA oncology, 2023, 01-01, Volume: 9, Issue:1

    Topics: Brain Neoplasms; Dendritic Cells; Glioblastoma; Humans; Prospective Studies; Recurrence; Temozolomid

2023
Trotabresib, an oral potent bromodomain and extraterminal inhibitor, in patients with high-grade gliomas: A phase I, "window-of-opportunity" study.
    Neuro-oncology, 2023, 06-02, Volume: 25, Issue:6

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Glioblastoma; Glioma; Humans; Temoz

2023
Trotabresib, an oral potent bromodomain and extraterminal inhibitor, in patients with high-grade gliomas: A phase I, "window-of-opportunity" study.
    Neuro-oncology, 2023, 06-02, Volume: 25, Issue:6

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Glioblastoma; Glioma; Humans; Temoz

2023
Trotabresib, an oral potent bromodomain and extraterminal inhibitor, in patients with high-grade gliomas: A phase I, "window-of-opportunity" study.
    Neuro-oncology, 2023, 06-02, Volume: 25, Issue:6

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Glioblastoma; Glioma; Humans; Temoz

2023
Trotabresib, an oral potent bromodomain and extraterminal inhibitor, in patients with high-grade gliomas: A phase I, "window-of-opportunity" study.
    Neuro-oncology, 2023, 06-02, Volume: 25, Issue:6

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Glioblastoma; Glioma; Humans; Temoz

2023
Trotabresib, an oral potent bromodomain and extraterminal inhibitor, in patients with high-grade gliomas: A phase I, "window-of-opportunity" study.
    Neuro-oncology, 2023, 06-02, Volume: 25, Issue:6

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Glioblastoma; Glioma; Humans; Temoz

2023
Trotabresib, an oral potent bromodomain and extraterminal inhibitor, in patients with high-grade gliomas: A phase I, "window-of-opportunity" study.
    Neuro-oncology, 2023, 06-02, Volume: 25, Issue:6

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Glioblastoma; Glioma; Humans; Temoz

2023
Trotabresib, an oral potent bromodomain and extraterminal inhibitor, in patients with high-grade gliomas: A phase I, "window-of-opportunity" study.
    Neuro-oncology, 2023, 06-02, Volume: 25, Issue:6

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Glioblastoma; Glioma; Humans; Temoz

2023
Trotabresib, an oral potent bromodomain and extraterminal inhibitor, in patients with high-grade gliomas: A phase I, "window-of-opportunity" study.
    Neuro-oncology, 2023, 06-02, Volume: 25, Issue:6

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Glioblastoma; Glioma; Humans; Temoz

2023
Trotabresib, an oral potent bromodomain and extraterminal inhibitor, in patients with high-grade gliomas: A phase I, "window-of-opportunity" study.
    Neuro-oncology, 2023, 06-02, Volume: 25, Issue:6

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Glioblastoma; Glioma; Humans; Temoz

2023
Trotabresib, an oral potent bromodomain and extraterminal inhibitor, in patients with high-grade gliomas: A phase I, "window-of-opportunity" study.
    Neuro-oncology, 2023, 06-02, Volume: 25, Issue:6

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Glioblastoma; Glioma; Humans; Temoz

2023
Trotabresib, an oral potent bromodomain and extraterminal inhibitor, in patients with high-grade gliomas: A phase I, "window-of-opportunity" study.
    Neuro-oncology, 2023, 06-02, Volume: 25, Issue:6

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Glioblastoma; Glioma; Humans; Temoz

2023
Trotabresib, an oral potent bromodomain and extraterminal inhibitor, in patients with high-grade gliomas: A phase I, "window-of-opportunity" study.
    Neuro-oncology, 2023, 06-02, Volume: 25, Issue:6

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Glioblastoma; Glioma; Humans; Temoz

2023
Phase 2 study of AV-GBM-1 (a tumor-initiating cell targeted dendritic cell vaccine) in newly diagnosed Glioblastoma patients: safety and efficacy assessment.
    Journal of experimental & clinical cancer research : CR, 2022, Dec-14, Volume: 41, Issue:1

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dendritic Cells; Gliobl

2022
Phase 2 study of AV-GBM-1 (a tumor-initiating cell targeted dendritic cell vaccine) in newly diagnosed Glioblastoma patients: safety and efficacy assessment.
    Journal of experimental & clinical cancer research : CR, 2022, Dec-14, Volume: 41, Issue:1

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dendritic Cells; Gliobl

2022
Phase 2 study of AV-GBM-1 (a tumor-initiating cell targeted dendritic cell vaccine) in newly diagnosed Glioblastoma patients: safety and efficacy assessment.
    Journal of experimental & clinical cancer research : CR, 2022, Dec-14, Volume: 41, Issue:1

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dendritic Cells; Gliobl

2022
Phase 2 study of AV-GBM-1 (a tumor-initiating cell targeted dendritic cell vaccine) in newly diagnosed Glioblastoma patients: safety and efficacy assessment.
    Journal of experimental & clinical cancer research : CR, 2022, Dec-14, Volume: 41, Issue:1

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dendritic Cells; Gliobl

2022
Phase 2 study of AV-GBM-1 (a tumor-initiating cell targeted dendritic cell vaccine) in newly diagnosed Glioblastoma patients: safety and efficacy assessment.
    Journal of experimental & clinical cancer research : CR, 2022, Dec-14, Volume: 41, Issue:1

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dendritic Cells; Gliobl

2022
Phase 2 study of AV-GBM-1 (a tumor-initiating cell targeted dendritic cell vaccine) in newly diagnosed Glioblastoma patients: safety and efficacy assessment.
    Journal of experimental & clinical cancer research : CR, 2022, Dec-14, Volume: 41, Issue:1

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dendritic Cells; Gliobl

2022
Phase 2 study of AV-GBM-1 (a tumor-initiating cell targeted dendritic cell vaccine) in newly diagnosed Glioblastoma patients: safety and efficacy assessment.
    Journal of experimental & clinical cancer research : CR, 2022, Dec-14, Volume: 41, Issue:1

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dendritic Cells; Gliobl

2022
Phase 2 study of AV-GBM-1 (a tumor-initiating cell targeted dendritic cell vaccine) in newly diagnosed Glioblastoma patients: safety and efficacy assessment.
    Journal of experimental & clinical cancer research : CR, 2022, Dec-14, Volume: 41, Issue:1

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dendritic Cells; Gliobl

2022
Phase 2 study of AV-GBM-1 (a tumor-initiating cell targeted dendritic cell vaccine) in newly diagnosed Glioblastoma patients: safety and efficacy assessment.
    Journal of experimental & clinical cancer research : CR, 2022, Dec-14, Volume: 41, Issue:1

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dendritic Cells; Gliobl

2022
Phase 2 study of AV-GBM-1 (a tumor-initiating cell targeted dendritic cell vaccine) in newly diagnosed Glioblastoma patients: safety and efficacy assessment.
    Journal of experimental & clinical cancer research : CR, 2022, Dec-14, Volume: 41, Issue:1

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dendritic Cells; Gliobl

2022
Phase 2 study of AV-GBM-1 (a tumor-initiating cell targeted dendritic cell vaccine) in newly diagnosed Glioblastoma patients: safety and efficacy assessment.
    Journal of experimental & clinical cancer research : CR, 2022, Dec-14, Volume: 41, Issue:1

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dendritic Cells; Gliobl

2022
Phase 2 study of AV-GBM-1 (a tumor-initiating cell targeted dendritic cell vaccine) in newly diagnosed Glioblastoma patients: safety and efficacy assessment.
    Journal of experimental & clinical cancer research : CR, 2022, Dec-14, Volume: 41, Issue:1

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dendritic Cells; Gliobl

2022
Phase IIa Study of SurVaxM Plus Adjuvant Temozolomide for Newly Diagnosed Glioblastoma.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2023, 03-01, Volume: 41, Issue:7

    Topics: Adjuvants, Immunologic; Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neo

2023
Phase IIa Study of SurVaxM Plus Adjuvant Temozolomide for Newly Diagnosed Glioblastoma.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2023, 03-01, Volume: 41, Issue:7

    Topics: Adjuvants, Immunologic; Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neo

2023
Phase IIa Study of SurVaxM Plus Adjuvant Temozolomide for Newly Diagnosed Glioblastoma.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2023, 03-01, Volume: 41, Issue:7

    Topics: Adjuvants, Immunologic; Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neo

2023
Phase IIa Study of SurVaxM Plus Adjuvant Temozolomide for Newly Diagnosed Glioblastoma.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2023, 03-01, Volume: 41, Issue:7

    Topics: Adjuvants, Immunologic; Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neo

2023
Phase IIa Study of SurVaxM Plus Adjuvant Temozolomide for Newly Diagnosed Glioblastoma.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2023, 03-01, Volume: 41, Issue:7

    Topics: Adjuvants, Immunologic; Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neo

2023
Phase IIa Study of SurVaxM Plus Adjuvant Temozolomide for Newly Diagnosed Glioblastoma.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2023, 03-01, Volume: 41, Issue:7

    Topics: Adjuvants, Immunologic; Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neo

2023
Phase IIa Study of SurVaxM Plus Adjuvant Temozolomide for Newly Diagnosed Glioblastoma.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2023, 03-01, Volume: 41, Issue:7

    Topics: Adjuvants, Immunologic; Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neo

2023
Phase IIa Study of SurVaxM Plus Adjuvant Temozolomide for Newly Diagnosed Glioblastoma.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2023, 03-01, Volume: 41, Issue:7

    Topics: Adjuvants, Immunologic; Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neo

2023
Phase IIa Study of SurVaxM Plus Adjuvant Temozolomide for Newly Diagnosed Glioblastoma.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2023, 03-01, Volume: 41, Issue:7

    Topics: Adjuvants, Immunologic; Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neo

2023
Phase IIa Study of SurVaxM Plus Adjuvant Temozolomide for Newly Diagnosed Glioblastoma.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2023, 03-01, Volume: 41, Issue:7

    Topics: Adjuvants, Immunologic; Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neo

2023
Phase IIa Study of SurVaxM Plus Adjuvant Temozolomide for Newly Diagnosed Glioblastoma.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2023, 03-01, Volume: 41, Issue:7

    Topics: Adjuvants, Immunologic; Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neo

2023
Phase IIa Study of SurVaxM Plus Adjuvant Temozolomide for Newly Diagnosed Glioblastoma.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2023, 03-01, Volume: 41, Issue:7

    Topics: Adjuvants, Immunologic; Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neo

2023
Patterns, predictors and prognostic relevance of high-grade hematotoxicity after temozolomide or temozolomide-lomustine in the CeTeG/NOA-09 trial.
    Journal of neuro-oncology, 2023, Volume: 161, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Female; Glioblastoma; Humans; Lomus

2023
Patterns, predictors and prognostic relevance of high-grade hematotoxicity after temozolomide or temozolomide-lomustine in the CeTeG/NOA-09 trial.
    Journal of neuro-oncology, 2023, Volume: 161, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Female; Glioblastoma; Humans; Lomus

2023
Patterns, predictors and prognostic relevance of high-grade hematotoxicity after temozolomide or temozolomide-lomustine in the CeTeG/NOA-09 trial.
    Journal of neuro-oncology, 2023, Volume: 161, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Female; Glioblastoma; Humans; Lomus

2023
Phase I Study and Cell-Free DNA Analysis of T-DM1 and Metronomic Temozolomide for Secondary Prevention of HER2-Positive Breast Cancer Brain Metastases.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2023, 04-14, Volume: 29, Issue:8

    Topics: Ado-Trastuzumab Emtansine; Brain Neoplasms; Breast Neoplasms; Cell-Free Nucleic Acids; Female; Human

2023
Phase I Study and Cell-Free DNA Analysis of T-DM1 and Metronomic Temozolomide for Secondary Prevention of HER2-Positive Breast Cancer Brain Metastases.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2023, 04-14, Volume: 29, Issue:8

    Topics: Ado-Trastuzumab Emtansine; Brain Neoplasms; Breast Neoplasms; Cell-Free Nucleic Acids; Female; Human

2023
Phase I Study and Cell-Free DNA Analysis of T-DM1 and Metronomic Temozolomide for Secondary Prevention of HER2-Positive Breast Cancer Brain Metastases.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2023, 04-14, Volume: 29, Issue:8

    Topics: Ado-Trastuzumab Emtansine; Brain Neoplasms; Breast Neoplasms; Cell-Free Nucleic Acids; Female; Human

2023
Adjuvant Temozolomide Chemotherapy With or Without Interferon Alfa Among Patients With Newly Diagnosed High-grade Gliomas: A Randomized Clinical Trial.
    JAMA network open, 2023, 01-03, Volume: 6, Issue:1

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Female; Gl

2023
Adjuvant Temozolomide Chemotherapy With or Without Interferon Alfa Among Patients With Newly Diagnosed High-grade Gliomas: A Randomized Clinical Trial.
    JAMA network open, 2023, 01-03, Volume: 6, Issue:1

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Female; Gl

2023
Adjuvant Temozolomide Chemotherapy With or Without Interferon Alfa Among Patients With Newly Diagnosed High-grade Gliomas: A Randomized Clinical Trial.
    JAMA network open, 2023, 01-03, Volume: 6, Issue:1

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Female; Gl

2023
A phase I clinical trial of sonodynamic therapy combined with temozolomide in the treatment of recurrent glioblastoma.
    Journal of neuro-oncology, 2023, Volume: 162, Issue:2

    Topics: Brain Neoplasms; Glioblastoma; Humans; Neoplasm Recurrence, Local; Pilot Projects; Prospective Studi

2023
A phase I clinical trial of sonodynamic therapy combined with temozolomide in the treatment of recurrent glioblastoma.
    Journal of neuro-oncology, 2023, Volume: 162, Issue:2

    Topics: Brain Neoplasms; Glioblastoma; Humans; Neoplasm Recurrence, Local; Pilot Projects; Prospective Studi

2023
A phase I clinical trial of sonodynamic therapy combined with temozolomide in the treatment of recurrent glioblastoma.
    Journal of neuro-oncology, 2023, Volume: 162, Issue:2

    Topics: Brain Neoplasms; Glioblastoma; Humans; Neoplasm Recurrence, Local; Pilot Projects; Prospective Studi

2023
Phase I/II study testing the combination of AGuIX nanoparticles with radiochemotherapy and concomitant temozolomide in patients with newly diagnosed glioblastoma (NANO-GBM trial protocol).
    BMC cancer, 2023, Apr-15, Volume: 23, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Clinical Trials, Phase I as T

2023
Phase I/II study testing the combination of AGuIX nanoparticles with radiochemotherapy and concomitant temozolomide in patients with newly diagnosed glioblastoma (NANO-GBM trial protocol).
    BMC cancer, 2023, Apr-15, Volume: 23, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Clinical Trials, Phase I as T

2023
Phase I/II study testing the combination of AGuIX nanoparticles with radiochemotherapy and concomitant temozolomide in patients with newly diagnosed glioblastoma (NANO-GBM trial protocol).
    BMC cancer, 2023, Apr-15, Volume: 23, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Clinical Trials, Phase I as T

2023
Phase I study of chlorogenic acid injection for recurrent high-grade glioma with long-term follow-up.
    Cancer biology & medicine, 2023, 06-22, Volume: 20, Issue:6

    Topics: Brain Neoplasms; Chlorogenic Acid; Dacarbazine; Follow-Up Studies; Glioma; Humans; Temozolomide

2023
Phase I study of chlorogenic acid injection for recurrent high-grade glioma with long-term follow-up.
    Cancer biology & medicine, 2023, 06-22, Volume: 20, Issue:6

    Topics: Brain Neoplasms; Chlorogenic Acid; Dacarbazine; Follow-Up Studies; Glioma; Humans; Temozolomide

2023
Phase I study of chlorogenic acid injection for recurrent high-grade glioma with long-term follow-up.
    Cancer biology & medicine, 2023, 06-22, Volume: 20, Issue:6

    Topics: Brain Neoplasms; Chlorogenic Acid; Dacarbazine; Follow-Up Studies; Glioma; Humans; Temozolomide

2023
Hypo-fractionated accelerated radiotherapy with concurrent and maintenance temozolomide in newly diagnosed glioblastoma: updated results from phase II HART-GBM trial.
    Journal of neuro-oncology, 2023, Volume: 164, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Disease-Free Survival; Glioblastoma; Humans; Tem

2023
Hypo-fractionated accelerated radiotherapy with concurrent and maintenance temozolomide in newly diagnosed glioblastoma: updated results from phase II HART-GBM trial.
    Journal of neuro-oncology, 2023, Volume: 164, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Disease-Free Survival; Glioblastoma; Humans; Tem

2023
Hypo-fractionated accelerated radiotherapy with concurrent and maintenance temozolomide in newly diagnosed glioblastoma: updated results from phase II HART-GBM trial.
    Journal of neuro-oncology, 2023, Volume: 164, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Disease-Free Survival; Glioblastoma; Humans; Tem

2023
Health-related quality-of-life results from the randomised phase II TAVAREC trial on temozolomide with or without bevacizumab in 1p/19q intact first-recurrence World Health Organization grade 2 and 3 glioma (European Organization for Research and Treatmen
    European journal of cancer (Oxford, England : 1990), 2023, Volume: 190

    Topics: Bevacizumab; Brain Neoplasms; Glioma; Humans; Quality of Life; Temozolomide; World Health Organizati

2023
Health-related quality-of-life results from the randomised phase II TAVAREC trial on temozolomide with or without bevacizumab in 1p/19q intact first-recurrence World Health Organization grade 2 and 3 glioma (European Organization for Research and Treatmen
    European journal of cancer (Oxford, England : 1990), 2023, Volume: 190

    Topics: Bevacizumab; Brain Neoplasms; Glioma; Humans; Quality of Life; Temozolomide; World Health Organizati

2023
Health-related quality-of-life results from the randomised phase II TAVAREC trial on temozolomide with or without bevacizumab in 1p/19q intact first-recurrence World Health Organization grade 2 and 3 glioma (European Organization for Research and Treatmen
    European journal of cancer (Oxford, England : 1990), 2023, Volume: 190

    Topics: Bevacizumab; Brain Neoplasms; Glioma; Humans; Quality of Life; Temozolomide; World Health Organizati

2023
Randomized open-label phase II trial of 5-day aprepitant plus ondansetron compared to ondansetron alone in the prevention of chemotherapy-induced nausea-vomiting (CINV) in glioma patients receiving adjuvant temozolomide.
    Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2020, Volume: 28, Issue:5

    Topics: Adult; Aged; Antiemetics; Antineoplastic Agents; Aprepitant; Brain Neoplasms; Female; Glioma; Humans

2020
Randomized open-label phase II trial of 5-day aprepitant plus ondansetron compared to ondansetron alone in the prevention of chemotherapy-induced nausea-vomiting (CINV) in glioma patients receiving adjuvant temozolomide.
    Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2020, Volume: 28, Issue:5

    Topics: Adult; Aged; Antiemetics; Antineoplastic Agents; Aprepitant; Brain Neoplasms; Female; Glioma; Humans

2020
Randomized open-label phase II trial of 5-day aprepitant plus ondansetron compared to ondansetron alone in the prevention of chemotherapy-induced nausea-vomiting (CINV) in glioma patients receiving adjuvant temozolomide.
    Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2020, Volume: 28, Issue:5

    Topics: Adult; Aged; Antiemetics; Antineoplastic Agents; Aprepitant; Brain Neoplasms; Female; Glioma; Humans

2020
Efficacy of initial temozolomide for high-risk low grade gliomas in a phase II AINO (Italian Association for Neuro-Oncology) study: a post-hoc analysis within molecular subgroups of WHO 2016.
    Journal of neuro-oncology, 2019, Volume: 145, Issue:1

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Female; Follow-Up Studies; Glioma;

2019
Efficacy of initial temozolomide for high-risk low grade gliomas in a phase II AINO (Italian Association for Neuro-Oncology) study: a post-hoc analysis within molecular subgroups of WHO 2016.
    Journal of neuro-oncology, 2019, Volume: 145, Issue:1

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Female; Follow-Up Studies; Glioma;

2019
Efficacy of initial temozolomide for high-risk low grade gliomas in a phase II AINO (Italian Association for Neuro-Oncology) study: a post-hoc analysis within molecular subgroups of WHO 2016.
    Journal of neuro-oncology, 2019, Volume: 145, Issue:1

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Female; Follow-Up Studies; Glioma;

2019
Romiplostim for temozolomide-induced thrombocytopenia in glioblastoma: The PLATUM trial.
    Neurology, 2019, 11-05, Volume: 93, Issue:19

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Female; Glioblas

2019
Romiplostim for temozolomide-induced thrombocytopenia in glioblastoma: The PLATUM trial.
    Neurology, 2019, 11-05, Volume: 93, Issue:19

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Female; Glioblas

2019
Romiplostim for temozolomide-induced thrombocytopenia in glioblastoma: The PLATUM trial.
    Neurology, 2019, 11-05, Volume: 93, Issue:19

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Female; Glioblas

2019
INTELLANCE 2/EORTC 1410 randomized phase II study of Depatux-M alone and with temozolomide vs temozolomide or lomustine in recurrent EGFR amplified glioblastoma.
    Neuro-oncology, 2020, 05-15, Volume: 22, Issue:5

    Topics: Antibodies, Monoclonal, Humanized; Antineoplastic Agents, Alkylating; Brain Neoplasms; ErbB Receptor

2020
INTELLANCE 2/EORTC 1410 randomized phase II study of Depatux-M alone and with temozolomide vs temozolomide or lomustine in recurrent EGFR amplified glioblastoma.
    Neuro-oncology, 2020, 05-15, Volume: 22, Issue:5

    Topics: Antibodies, Monoclonal, Humanized; Antineoplastic Agents, Alkylating; Brain Neoplasms; ErbB Receptor

2020
INTELLANCE 2/EORTC 1410 randomized phase II study of Depatux-M alone and with temozolomide vs temozolomide or lomustine in recurrent EGFR amplified glioblastoma.
    Neuro-oncology, 2020, 05-15, Volume: 22, Issue:5

    Topics: Antibodies, Monoclonal, Humanized; Antineoplastic Agents, Alkylating; Brain Neoplasms; ErbB Receptor

2020
Radiotherapy versus radiotherapy combined with temozolomide in high-risk low-grade gliomas after surgery: study protocol for a randomized controlled clinical trial.
    Trials, 2019, Nov-21, Volume: 20, Issue:1

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy, Adju

2019
Radiotherapy versus radiotherapy combined with temozolomide in high-risk low-grade gliomas after surgery: study protocol for a randomized controlled clinical trial.
    Trials, 2019, Nov-21, Volume: 20, Issue:1

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy, Adju

2019
Radiotherapy versus radiotherapy combined with temozolomide in high-risk low-grade gliomas after surgery: study protocol for a randomized controlled clinical trial.
    Trials, 2019, Nov-21, Volume: 20, Issue:1

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy, Adju

2019
A multicenter randomized phase III study for newly diagnosed maximally resected glioblastoma comparing carmustine wafer implantation followed by chemoradiotherapy with temozolomide with chemoradiotherapy alone; Japan Clinical Oncology Group Study JCOG1703
    Japanese journal of clinical oncology, 2019, Dec-27, Volume: 49, Issue:12

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Carmustine; Chemoradiotherapy, Adjuvant; Drug Im

2019
A multicenter randomized phase III study for newly diagnosed maximally resected glioblastoma comparing carmustine wafer implantation followed by chemoradiotherapy with temozolomide with chemoradiotherapy alone; Japan Clinical Oncology Group Study JCOG1703
    Japanese journal of clinical oncology, 2019, Dec-27, Volume: 49, Issue:12

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Carmustine; Chemoradiotherapy, Adjuvant; Drug Im

2019
A multicenter randomized phase III study for newly diagnosed maximally resected glioblastoma comparing carmustine wafer implantation followed by chemoradiotherapy with temozolomide with chemoradiotherapy alone; Japan Clinical Oncology Group Study JCOG1703
    Japanese journal of clinical oncology, 2019, Dec-27, Volume: 49, Issue:12

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Carmustine; Chemoradiotherapy, Adjuvant; Drug Im

2019
A phase I/II trial of 5-fraction stereotactic radiosurgery with 5-mm margins with concurrent temozolomide in newly diagnosed glioblastoma: primary outcomes.
    Neuro-oncology, 2020, 08-17, Volume: 22, Issue:8

    Topics: Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Fema

2020
A phase I/II trial of 5-fraction stereotactic radiosurgery with 5-mm margins with concurrent temozolomide in newly diagnosed glioblastoma: primary outcomes.
    Neuro-oncology, 2020, 08-17, Volume: 22, Issue:8

    Topics: Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Fema

2020
A phase I/II trial of 5-fraction stereotactic radiosurgery with 5-mm margins with concurrent temozolomide in newly diagnosed glioblastoma: primary outcomes.
    Neuro-oncology, 2020, 08-17, Volume: 22, Issue:8

    Topics: Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Fema

2020
A phase I/II study of veliparib (ABT-888) with radiation and temozolomide in newly diagnosed diffuse pontine glioma: a Pediatric Brain Tumor Consortium study.
    Neuro-oncology, 2020, 06-09, Volume: 22, Issue:6

    Topics: Antineoplastic Combined Chemotherapy Protocols; Benzimidazoles; Brain Neoplasms; Brain Stem Neoplasm

2020
A phase I/II study of veliparib (ABT-888) with radiation and temozolomide in newly diagnosed diffuse pontine glioma: a Pediatric Brain Tumor Consortium study.
    Neuro-oncology, 2020, 06-09, Volume: 22, Issue:6

    Topics: Antineoplastic Combined Chemotherapy Protocols; Benzimidazoles; Brain Neoplasms; Brain Stem Neoplasm

2020
A phase I/II study of veliparib (ABT-888) with radiation and temozolomide in newly diagnosed diffuse pontine glioma: a Pediatric Brain Tumor Consortium study.
    Neuro-oncology, 2020, 06-09, Volume: 22, Issue:6

    Topics: Antineoplastic Combined Chemotherapy Protocols; Benzimidazoles; Brain Neoplasms; Brain Stem Neoplasm

2020
Tumor treating fields plus temozolomide for newly diagnosed glioblastoma: a sub-group analysis of Korean patients in the EF-14 phase 3 trial.
    Journal of neuro-oncology, 2020, Volume: 146, Issue:3

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Asian People; Brain Neoplasms; Electric Stimulation

2020
Tumor treating fields plus temozolomide for newly diagnosed glioblastoma: a sub-group analysis of Korean patients in the EF-14 phase 3 trial.
    Journal of neuro-oncology, 2020, Volume: 146, Issue:3

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Asian People; Brain Neoplasms; Electric Stimulation

2020
Tumor treating fields plus temozolomide for newly diagnosed glioblastoma: a sub-group analysis of Korean patients in the EF-14 phase 3 trial.
    Journal of neuro-oncology, 2020, Volume: 146, Issue:3

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Asian People; Brain Neoplasms; Electric Stimulation

2020
Phase 1b/2a study of galunisertib, a small molecule inhibitor of transforming growth factor-beta receptor I, in combination with standard temozolomide-based radiochemotherapy in patients with newly diagnosed malignant glioma.
    Investigational new drugs, 2020, Volume: 38, Issue:5

    Topics: Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Brai

2020
Phase 1b/2a study of galunisertib, a small molecule inhibitor of transforming growth factor-beta receptor I, in combination with standard temozolomide-based radiochemotherapy in patients with newly diagnosed malignant glioma.
    Investigational new drugs, 2020, Volume: 38, Issue:5

    Topics: Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Brai

2020
Phase 1b/2a study of galunisertib, a small molecule inhibitor of transforming growth factor-beta receptor I, in combination with standard temozolomide-based radiochemotherapy in patients with newly diagnosed malignant glioma.
    Investigational new drugs, 2020, Volume: 38, Issue:5

    Topics: Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Brai

2020
Clinical and histopathological analyses of VEGF receptors peptide vaccine in patients with primary glioblastoma - a case series.
    BMC cancer, 2020, Mar-12, Volume: 20, Issue:1

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cancer Vaccines; Drug Synergism; Fe

2020
Clinical and histopathological analyses of VEGF receptors peptide vaccine in patients with primary glioblastoma - a case series.
    BMC cancer, 2020, Mar-12, Volume: 20, Issue:1

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cancer Vaccines; Drug Synergism; Fe

2020
Clinical and histopathological analyses of VEGF receptors peptide vaccine in patients with primary glioblastoma - a case series.
    BMC cancer, 2020, Mar-12, Volume: 20, Issue:1

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cancer Vaccines; Drug Synergism; Fe

2020
A phase II open label, randomised study of ipilimumab with temozolomide versus temozolomide alone after surgery and chemoradiotherapy in patients with recently diagnosed glioblastoma: the Ipi-Glio trial protocol.
    BMC cancer, 2020, Mar-12, Volume: 20, Issue:1

    Topics: Adult; Aged; Brain Neoplasms; Chemoradiotherapy; Cytoreduction Surgical Procedures; Female; Glioblas

2020
A phase II open label, randomised study of ipilimumab with temozolomide versus temozolomide alone after surgery and chemoradiotherapy in patients with recently diagnosed glioblastoma: the Ipi-Glio trial protocol.
    BMC cancer, 2020, Mar-12, Volume: 20, Issue:1

    Topics: Adult; Aged; Brain Neoplasms; Chemoradiotherapy; Cytoreduction Surgical Procedures; Female; Glioblas

2020
A phase II open label, randomised study of ipilimumab with temozolomide versus temozolomide alone after surgery and chemoradiotherapy in patients with recently diagnosed glioblastoma: the Ipi-Glio trial protocol.
    BMC cancer, 2020, Mar-12, Volume: 20, Issue:1

    Topics: Adult; Aged; Brain Neoplasms; Chemoradiotherapy; Cytoreduction Surgical Procedures; Female; Glioblas

2020
Initial experience with scalp sparing radiation with concurrent temozolomide and tumor treatment fields (SPARE) for patients with newly diagnosed glioblastoma.
    Journal of neuro-oncology, 2020, Volume: 147, Issue:3

    Topics: Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Combined Modality Thera

2020
Initial experience with scalp sparing radiation with concurrent temozolomide and tumor treatment fields (SPARE) for patients with newly diagnosed glioblastoma.
    Journal of neuro-oncology, 2020, Volume: 147, Issue:3

    Topics: Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Combined Modality Thera

2020
Initial experience with scalp sparing radiation with concurrent temozolomide and tumor treatment fields (SPARE) for patients with newly diagnosed glioblastoma.
    Journal of neuro-oncology, 2020, Volume: 147, Issue:3

    Topics: Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Combined Modality Thera

2020
Image-based metric of invasiveness predicts response to adjuvant temozolomide for primary glioblastoma.
    PloS one, 2020, Volume: 15, Issue:3

    Topics: Adolescent; Adult; Age Factors; Aged; Brain Neoplasms; DNA Methylation; DNA Modification Methylases;

2020
Image-based metric of invasiveness predicts response to adjuvant temozolomide for primary glioblastoma.
    PloS one, 2020, Volume: 15, Issue:3

    Topics: Adolescent; Adult; Age Factors; Aged; Brain Neoplasms; DNA Methylation; DNA Modification Methylases;

2020
Image-based metric of invasiveness predicts response to adjuvant temozolomide for primary glioblastoma.
    PloS one, 2020, Volume: 15, Issue:3

    Topics: Adolescent; Adult; Age Factors; Aged; Brain Neoplasms; DNA Methylation; DNA Modification Methylases;

2020
Phase 2 Study of a Temozolomide-Based Chemoradiation Therapy Regimen for High-Risk, Low-Grade Gliomas: Long-Term Results of Radiation Therapy Oncology Group 0424.
    International journal of radiation oncology, biology, physics, 2020, 07-15, Volume: 107, Issue:4

    Topics: Adult; Brain Neoplasms; Chemoradiotherapy; Female; Glioma; Humans; Kaplan-Meier Estimate; Male; Neop

2020
Phase 2 Study of a Temozolomide-Based Chemoradiation Therapy Regimen for High-Risk, Low-Grade Gliomas: Long-Term Results of Radiation Therapy Oncology Group 0424.
    International journal of radiation oncology, biology, physics, 2020, 07-15, Volume: 107, Issue:4

    Topics: Adult; Brain Neoplasms; Chemoradiotherapy; Female; Glioma; Humans; Kaplan-Meier Estimate; Male; Neop

2020
Phase 2 Study of a Temozolomide-Based Chemoradiation Therapy Regimen for High-Risk, Low-Grade Gliomas: Long-Term Results of Radiation Therapy Oncology Group 0424.
    International journal of radiation oncology, biology, physics, 2020, 07-15, Volume: 107, Issue:4

    Topics: Adult; Brain Neoplasms; Chemoradiotherapy; Female; Glioma; Humans; Kaplan-Meier Estimate; Male; Neop

2020
Temozolomide in secondary prevention of HER2-positive breast cancer brain metastases.
    Future oncology (London, England), 2020, Volume: 16, Issue:14

    Topics: Animals; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Biomarke

2020
Temozolomide in secondary prevention of HER2-positive breast cancer brain metastases.
    Future oncology (London, England), 2020, Volume: 16, Issue:14

    Topics: Animals; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Biomarke

2020
Temozolomide in secondary prevention of HER2-positive breast cancer brain metastases.
    Future oncology (London, England), 2020, Volume: 16, Issue:14

    Topics: Animals; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Biomarke

2020
Simultaneous detection of EGFR amplification and EGFRvIII variant using digital PCR-based method in glioblastoma.
    Acta neuropathologica communications, 2020, 04-17, Volume: 8, Issue:1

    Topics: Adult; Aged; Biomarkers; Brain Neoplasms; Chemoradiotherapy; ErbB Receptors; Female; Gene Amplificat

2020
Simultaneous detection of EGFR amplification and EGFRvIII variant using digital PCR-based method in glioblastoma.
    Acta neuropathologica communications, 2020, 04-17, Volume: 8, Issue:1

    Topics: Adult; Aged; Biomarkers; Brain Neoplasms; Chemoradiotherapy; ErbB Receptors; Female; Gene Amplificat

2020
Simultaneous detection of EGFR amplification and EGFRvIII variant using digital PCR-based method in glioblastoma.
    Acta neuropathologica communications, 2020, 04-17, Volume: 8, Issue:1

    Topics: Adult; Aged; Biomarkers; Brain Neoplasms; Chemoradiotherapy; ErbB Receptors; Female; Gene Amplificat

2020
A phase II randomized, multicenter, open-label trial of continuing adjuvant temozolomide beyond 6 cycles in patients with glioblastoma (GEINO 14-01).
    Neuro-oncology, 2020, 12-18, Volume: 22, Issue:12

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Disease-Free Survival; Glioblastoma; Humans; Tem

2020
A phase II randomized, multicenter, open-label trial of continuing adjuvant temozolomide beyond 6 cycles in patients with glioblastoma (GEINO 14-01).
    Neuro-oncology, 2020, 12-18, Volume: 22, Issue:12

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Disease-Free Survival; Glioblastoma; Humans; Tem

2020
A phase II randomized, multicenter, open-label trial of continuing adjuvant temozolomide beyond 6 cycles in patients with glioblastoma (GEINO 14-01).
    Neuro-oncology, 2020, 12-18, Volume: 22, Issue:12

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Disease-Free Survival; Glioblastoma; Humans; Tem

2020
Genetic analysis in patients with newly diagnosed glioblastomas treated with interferon-beta plus temozolomide in comparison with temozolomide alone.
    Journal of neuro-oncology, 2020, Volume: 148, Issue:1

    Topics: Adult; Aged; Antineoplastic Agents; Brain Neoplasms; DNA Modification Methylases; DNA Repair Enzymes

2020
Genetic analysis in patients with newly diagnosed glioblastomas treated with interferon-beta plus temozolomide in comparison with temozolomide alone.
    Journal of neuro-oncology, 2020, Volume: 148, Issue:1

    Topics: Adult; Aged; Antineoplastic Agents; Brain Neoplasms; DNA Modification Methylases; DNA Repair Enzymes

2020
Genetic analysis in patients with newly diagnosed glioblastomas treated with interferon-beta plus temozolomide in comparison with temozolomide alone.
    Journal of neuro-oncology, 2020, Volume: 148, Issue:1

    Topics: Adult; Aged; Antineoplastic Agents; Brain Neoplasms; DNA Modification Methylases; DNA Repair Enzymes

2020
Effect of Nivolumab vs Bevacizumab in Patients With Recurrent Glioblastoma: The CheckMate 143 Phase 3 Randomized Clinical Trial.
    JAMA oncology, 2020, 07-01, Volume: 6, Issue:7

    Topics: Adult; Aged; Angiogenesis Inhibitors; Antineoplastic Agents, Immunological; Bevacizumab; Brain Neopl

2020
Effect of Nivolumab vs Bevacizumab in Patients With Recurrent Glioblastoma: The CheckMate 143 Phase 3 Randomized Clinical Trial.
    JAMA oncology, 2020, 07-01, Volume: 6, Issue:7

    Topics: Adult; Aged; Angiogenesis Inhibitors; Antineoplastic Agents, Immunological; Bevacizumab; Brain Neopl

2020
Effect of Nivolumab vs Bevacizumab in Patients With Recurrent Glioblastoma: The CheckMate 143 Phase 3 Randomized Clinical Trial.
    JAMA oncology, 2020, 07-01, Volume: 6, Issue:7

    Topics: Adult; Aged; Angiogenesis Inhibitors; Antineoplastic Agents, Immunological; Bevacizumab; Brain Neopl

2020
Temozolomide and seizure outcomes in a randomized clinical trial of elderly glioblastoma patients.
    Journal of neuro-oncology, 2020, Volume: 149, Issue:1

    Topics: Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Female; Follow-Up Studi

2020
Temozolomide and seizure outcomes in a randomized clinical trial of elderly glioblastoma patients.
    Journal of neuro-oncology, 2020, Volume: 149, Issue:1

    Topics: Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Female; Follow-Up Studi

2020
Temozolomide and seizure outcomes in a randomized clinical trial of elderly glioblastoma patients.
    Journal of neuro-oncology, 2020, Volume: 149, Issue:1

    Topics: Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Female; Follow-Up Studi

2020
CODEL: phase III study of RT, RT + TMZ, or TMZ for newly diagnosed 1p/19q codeleted oligodendroglioma. Analysis from the initial study design.
    Neuro-oncology, 2021, 03-25, Volume: 23, Issue:3

    Topics: Adult; Brain Neoplasms; Humans; Isocitrate Dehydrogenase; Oligodendroglioma; Progression-Free Surviv

2021
CODEL: phase III study of RT, RT + TMZ, or TMZ for newly diagnosed 1p/19q codeleted oligodendroglioma. Analysis from the initial study design.
    Neuro-oncology, 2021, 03-25, Volume: 23, Issue:3

    Topics: Adult; Brain Neoplasms; Humans; Isocitrate Dehydrogenase; Oligodendroglioma; Progression-Free Surviv

2021
CODEL: phase III study of RT, RT + TMZ, or TMZ for newly diagnosed 1p/19q codeleted oligodendroglioma. Analysis from the initial study design.
    Neuro-oncology, 2021, 03-25, Volume: 23, Issue:3

    Topics: Adult; Brain Neoplasms; Humans; Isocitrate Dehydrogenase; Oligodendroglioma; Progression-Free Surviv

2021
Atorvastatin in combination with radiotherapy and temozolomide for glioblastoma: a prospective phase II study.
    Investigational new drugs, 2021, Volume: 39, Issue:1

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Atorvastatin; Brain Neoplasms; Chemoradiotherapy; Fe

2021
Atorvastatin in combination with radiotherapy and temozolomide for glioblastoma: a prospective phase II study.
    Investigational new drugs, 2021, Volume: 39, Issue:1

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Atorvastatin; Brain Neoplasms; Chemoradiotherapy; Fe

2021
Atorvastatin in combination with radiotherapy and temozolomide for glioblastoma: a prospective phase II study.
    Investigational new drugs, 2021, Volume: 39, Issue:1

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Atorvastatin; Brain Neoplasms; Chemoradiotherapy; Fe

2021
Psychological distress among health care professionals of the three COVID-19 most affected Regions in Cameroon: Prevalence and associated factors.
    Annales medico-psychologiques, 2021, Volume: 179, Issue:2

    Topics: 3' Untranslated Regions; 5'-Nucleotidase; A549 Cells; Accidental Falls; Acetylcholinesterase; Acryli

2021
Psychological distress among health care professionals of the three COVID-19 most affected Regions in Cameroon: Prevalence and associated factors.
    Annales medico-psychologiques, 2021, Volume: 179, Issue:2

    Topics: 3' Untranslated Regions; 5'-Nucleotidase; A549 Cells; Accidental Falls; Acetylcholinesterase; Acryli

2021
Psychological distress among health care professionals of the three COVID-19 most affected Regions in Cameroon: Prevalence and associated factors.
    Annales medico-psychologiques, 2021, Volume: 179, Issue:2

    Topics: 3' Untranslated Regions; 5'-Nucleotidase; A549 Cells; Accidental Falls; Acetylcholinesterase; Acryli

2021
Psychological distress among health care professionals of the three COVID-19 most affected Regions in Cameroon: Prevalence and associated factors.
    Annales medico-psychologiques, 2021, Volume: 179, Issue:2

    Topics: 3' Untranslated Regions; 5'-Nucleotidase; A549 Cells; Accidental Falls; Acetylcholinesterase; Acryli

2021
Psychological distress among health care professionals of the three COVID-19 most affected Regions in Cameroon: Prevalence and associated factors.
    Annales medico-psychologiques, 2021, Volume: 179, Issue:2

    Topics: 3' Untranslated Regions; 5'-Nucleotidase; A549 Cells; Accidental Falls; Acetylcholinesterase; Acryli

2021
Psychological distress among health care professionals of the three COVID-19 most affected Regions in Cameroon: Prevalence and associated factors.
    Annales medico-psychologiques, 2021, Volume: 179, Issue:2

    Topics: 3' Untranslated Regions; 5'-Nucleotidase; A549 Cells; Accidental Falls; Acetylcholinesterase; Acryli

2021
Psychological distress among health care professionals of the three COVID-19 most affected Regions in Cameroon: Prevalence and associated factors.
    Annales medico-psychologiques, 2021, Volume: 179, Issue:2

    Topics: 3' Untranslated Regions; 5'-Nucleotidase; A549 Cells; Accidental Falls; Acetylcholinesterase; Acryli

2021
Psychological distress among health care professionals of the three COVID-19 most affected Regions in Cameroon: Prevalence and associated factors.
    Annales medico-psychologiques, 2021, Volume: 179, Issue:2

    Topics: 3' Untranslated Regions; 5'-Nucleotidase; A549 Cells; Accidental Falls; Acetylcholinesterase; Acryli

2021
Psychological distress among health care professionals of the three COVID-19 most affected Regions in Cameroon: Prevalence and associated factors.
    Annales medico-psychologiques, 2021, Volume: 179, Issue:2

    Topics: 3' Untranslated Regions; 5'-Nucleotidase; A549 Cells; Accidental Falls; Acetylcholinesterase; Acryli

2021
Psychological distress among health care professionals of the three COVID-19 most affected Regions in Cameroon: Prevalence and associated factors.
    Annales medico-psychologiques, 2021, Volume: 179, Issue:2

    Topics: 3' Untranslated Regions; 5'-Nucleotidase; A549 Cells; Accidental Falls; Acetylcholinesterase; Acryli

2021
Psychological distress among health care professionals of the three COVID-19 most affected Regions in Cameroon: Prevalence and associated factors.
    Annales medico-psychologiques, 2021, Volume: 179, Issue:2

    Topics: 3' Untranslated Regions; 5'-Nucleotidase; A549 Cells; Accidental Falls; Acetylcholinesterase; Acryli

2021
Psychological distress among health care professionals of the three COVID-19 most affected Regions in Cameroon: Prevalence and associated factors.
    Annales medico-psychologiques, 2021, Volume: 179, Issue:2

    Topics: 3' Untranslated Regions; 5'-Nucleotidase; A549 Cells; Accidental Falls; Acetylcholinesterase; Acryli

2021
A phase II study of dose-dense temozolomide and lapatinib for recurrent low-grade and anaplastic supratentorial, infratentorial, and spinal cord ependymoma.
    Neuro-oncology, 2021, 03-25, Volume: 23, Issue:3

    Topics: Adolescent; Adult; Brain Neoplasms; Dacarbazine; Disease-Free Survival; Ependymoma; Humans; Lapatini

2021
A phase II study of dose-dense temozolomide and lapatinib for recurrent low-grade and anaplastic supratentorial, infratentorial, and spinal cord ependymoma.
    Neuro-oncology, 2021, 03-25, Volume: 23, Issue:3

    Topics: Adolescent; Adult; Brain Neoplasms; Dacarbazine; Disease-Free Survival; Ependymoma; Humans; Lapatini

2021
A phase II study of dose-dense temozolomide and lapatinib for recurrent low-grade and anaplastic supratentorial, infratentorial, and spinal cord ependymoma.
    Neuro-oncology, 2021, 03-25, Volume: 23, Issue:3

    Topics: Adolescent; Adult; Brain Neoplasms; Dacarbazine; Disease-Free Survival; Ependymoma; Humans; Lapatini

2021
MGMT promoter methylation analysis for allocating combined CCNU/TMZ chemotherapy: Lessons learned from the CeTeG/NOA-09 trial.
    International journal of cancer, 2021, 04-01, Volume: 148, Issue:7

    Topics: Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor

2021
MGMT promoter methylation analysis for allocating combined CCNU/TMZ chemotherapy: Lessons learned from the CeTeG/NOA-09 trial.
    International journal of cancer, 2021, 04-01, Volume: 148, Issue:7

    Topics: Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor

2021
MGMT promoter methylation analysis for allocating combined CCNU/TMZ chemotherapy: Lessons learned from the CeTeG/NOA-09 trial.
    International journal of cancer, 2021, 04-01, Volume: 148, Issue:7

    Topics: Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor

2021
Effect of Vocimagene Amiretrorepvec in Combination With Flucytosine vs Standard of Care on Survival Following Tumor Resection in Patients With Recurrent High-Grade Glioma: A Randomized Clinical Trial.
    JAMA oncology, 2020, 12-01, Volume: 6, Issue:12

    Topics: Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Brain Neop

2020
Effect of Vocimagene Amiretrorepvec in Combination With Flucytosine vs Standard of Care on Survival Following Tumor Resection in Patients With Recurrent High-Grade Glioma: A Randomized Clinical Trial.
    JAMA oncology, 2020, 12-01, Volume: 6, Issue:12

    Topics: Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Brain Neop

2020
Effect of Vocimagene Amiretrorepvec in Combination With Flucytosine vs Standard of Care on Survival Following Tumor Resection in Patients With Recurrent High-Grade Glioma: A Randomized Clinical Trial.
    JAMA oncology, 2020, 12-01, Volume: 6, Issue:12

    Topics: Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Brain Neop

2020
Nanoliposomal Irinotecan and Metronomic Temozolomide for Patients With Recurrent Glioblastoma: BrUOG329, A Phase I Brown University Oncology Research Group Trial.
    American journal of clinical oncology, 2021, 02-01, Volume: 44, Issue:2

    Topics: Administration, Metronomic; Adult; Aged; Anorexia; Antineoplastic Combined Chemotherapy Protocols; B

2021
Nanoliposomal Irinotecan and Metronomic Temozolomide for Patients With Recurrent Glioblastoma: BrUOG329, A Phase I Brown University Oncology Research Group Trial.
    American journal of clinical oncology, 2021, 02-01, Volume: 44, Issue:2

    Topics: Administration, Metronomic; Adult; Aged; Anorexia; Antineoplastic Combined Chemotherapy Protocols; B

2021
Nanoliposomal Irinotecan and Metronomic Temozolomide for Patients With Recurrent Glioblastoma: BrUOG329, A Phase I Brown University Oncology Research Group Trial.
    American journal of clinical oncology, 2021, 02-01, Volume: 44, Issue:2

    Topics: Administration, Metronomic; Adult; Aged; Anorexia; Antineoplastic Combined Chemotherapy Protocols; B

2021
A phase 1b randomised, placebo-controlled trial of nabiximols cannabinoid oromucosal spray with temozolomide in patients with recurrent glioblastoma.
    British journal of cancer, 2021, Volume: 124, Issue:8

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Cannabidiol; Dose-Resp

2021
A phase 1b randomised, placebo-controlled trial of nabiximols cannabinoid oromucosal spray with temozolomide in patients with recurrent glioblastoma.
    British journal of cancer, 2021, Volume: 124, Issue:8

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Cannabidiol; Dose-Resp

2021
A phase 1b randomised, placebo-controlled trial of nabiximols cannabinoid oromucosal spray with temozolomide in patients with recurrent glioblastoma.
    British journal of cancer, 2021, Volume: 124, Issue:8

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Cannabidiol; Dose-Resp

2021
A phase 1b randomised, placebo-controlled trial of nabiximols cannabinoid oromucosal spray with temozolomide in patients with recurrent glioblastoma.
    British journal of cancer, 2021, Volume: 124, Issue:8

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Cannabidiol; Dose-Resp

2021
A phase 1b randomised, placebo-controlled trial of nabiximols cannabinoid oromucosal spray with temozolomide in patients with recurrent glioblastoma.
    British journal of cancer, 2021, Volume: 124, Issue:8

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Cannabidiol; Dose-Resp

2021
A phase 1b randomised, placebo-controlled trial of nabiximols cannabinoid oromucosal spray with temozolomide in patients with recurrent glioblastoma.
    British journal of cancer, 2021, Volume: 124, Issue:8

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Cannabidiol; Dose-Resp

2021
A phase 1b randomised, placebo-controlled trial of nabiximols cannabinoid oromucosal spray with temozolomide in patients with recurrent glioblastoma.
    British journal of cancer, 2021, Volume: 124, Issue:8

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Cannabidiol; Dose-Resp

2021
A phase 1b randomised, placebo-controlled trial of nabiximols cannabinoid oromucosal spray with temozolomide in patients with recurrent glioblastoma.
    British journal of cancer, 2021, Volume: 124, Issue:8

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Cannabidiol; Dose-Resp

2021
A phase 1b randomised, placebo-controlled trial of nabiximols cannabinoid oromucosal spray with temozolomide in patients with recurrent glioblastoma.
    British journal of cancer, 2021, Volume: 124, Issue:8

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Cannabidiol; Dose-Resp

2021
A phase 1b randomised, placebo-controlled trial of nabiximols cannabinoid oromucosal spray with temozolomide in patients with recurrent glioblastoma.
    British journal of cancer, 2021, Volume: 124, Issue:8

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Cannabidiol; Dose-Resp

2021
A phase 1b randomised, placebo-controlled trial of nabiximols cannabinoid oromucosal spray with temozolomide in patients with recurrent glioblastoma.
    British journal of cancer, 2021, Volume: 124, Issue:8

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Cannabidiol; Dose-Resp

2021
A phase 1b randomised, placebo-controlled trial of nabiximols cannabinoid oromucosal spray with temozolomide in patients with recurrent glioblastoma.
    British journal of cancer, 2021, Volume: 124, Issue:8

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Cannabidiol; Dose-Resp

2021
Initial Results of a Phase 2 Trial of
    International journal of radiation oncology, biology, physics, 2021, 08-01, Volume: 110, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Immunologi

2021
Initial Results of a Phase 2 Trial of
    International journal of radiation oncology, biology, physics, 2021, 08-01, Volume: 110, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Immunologi

2021
Initial Results of a Phase 2 Trial of
    International journal of radiation oncology, biology, physics, 2021, 08-01, Volume: 110, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Immunologi

2021
Phase I Study of Zotiraciclib in Combination with Temozolomide for Patients with Recurrent High-grade Astrocytomas.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2021, 06-15, Volume: 27, Issue:12

    Topics: Antineoplastic Combined Chemotherapy Protocols; Astrocytoma; Bayes Theorem; Brain Neoplasms; Dacarba

2021
Phase I Study of Zotiraciclib in Combination with Temozolomide for Patients with Recurrent High-grade Astrocytomas.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2021, 06-15, Volume: 27, Issue:12

    Topics: Antineoplastic Combined Chemotherapy Protocols; Astrocytoma; Bayes Theorem; Brain Neoplasms; Dacarba

2021
Phase I Study of Zotiraciclib in Combination with Temozolomide for Patients with Recurrent High-grade Astrocytomas.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2021, 06-15, Volume: 27, Issue:12

    Topics: Antineoplastic Combined Chemotherapy Protocols; Astrocytoma; Bayes Theorem; Brain Neoplasms; Dacarba

2021
A randomized phase II trial of veliparib, radiotherapy, and temozolomide in patients with unmethylated MGMT glioblastoma: the VERTU study.
    Neuro-oncology, 2021, 10-01, Volume: 23, Issue:10

    Topics: Antineoplastic Agents, Alkylating; Benzimidazoles; Brain Neoplasms; DNA Methylation; DNA Modificatio

2021
A randomized phase II trial of veliparib, radiotherapy, and temozolomide in patients with unmethylated MGMT glioblastoma: the VERTU study.
    Neuro-oncology, 2021, 10-01, Volume: 23, Issue:10

    Topics: Antineoplastic Agents, Alkylating; Benzimidazoles; Brain Neoplasms; DNA Methylation; DNA Modificatio

2021
A randomized phase II trial of veliparib, radiotherapy, and temozolomide in patients with unmethylated MGMT glioblastoma: the VERTU study.
    Neuro-oncology, 2021, 10-01, Volume: 23, Issue:10

    Topics: Antineoplastic Agents, Alkylating; Benzimidazoles; Brain Neoplasms; DNA Methylation; DNA Modificatio

2021
Influence of Concurrent and Adjuvant Temozolomide on Health-Related Quality of Life of Patients with Grade III Gliomas: A Secondary Analysis of a Randomized Clinical Trial (KNOG-1101 Study).
    Cancer research and treatment, 2022, Volume: 54, Issue:2

    Topics: Brain Neoplasms; Chemoradiotherapy; Glioma; Humans; Lymphoma, Follicular; Quality of Life; Temozolom

2022
Influence of Concurrent and Adjuvant Temozolomide on Health-Related Quality of Life of Patients with Grade III Gliomas: A Secondary Analysis of a Randomized Clinical Trial (KNOG-1101 Study).
    Cancer research and treatment, 2022, Volume: 54, Issue:2

    Topics: Brain Neoplasms; Chemoradiotherapy; Glioma; Humans; Lymphoma, Follicular; Quality of Life; Temozolom

2022
Influence of Concurrent and Adjuvant Temozolomide on Health-Related Quality of Life of Patients with Grade III Gliomas: A Secondary Analysis of a Randomized Clinical Trial (KNOG-1101 Study).
    Cancer research and treatment, 2022, Volume: 54, Issue:2

    Topics: Brain Neoplasms; Chemoradiotherapy; Glioma; Humans; Lymphoma, Follicular; Quality of Life; Temozolom

2022
The need for geriatric scales in glioblastoma.
    Aging, 2021, 07-23, Volume: 13, Issue:14

    Topics: Adult; Age Factors; Aged; Aged, 80 and over; Brain Neoplasms; Chemoradiotherapy; Female; Glioblastom

2021
The need for geriatric scales in glioblastoma.
    Aging, 2021, 07-23, Volume: 13, Issue:14

    Topics: Adult; Age Factors; Aged; Aged, 80 and over; Brain Neoplasms; Chemoradiotherapy; Female; Glioblastom

2021
The need for geriatric scales in glioblastoma.
    Aging, 2021, 07-23, Volume: 13, Issue:14

    Topics: Adult; Age Factors; Aged; Aged, 80 and over; Brain Neoplasms; Chemoradiotherapy; Female; Glioblastom

2021
Timed sequential therapy of the selective T-type calcium channel blocker mibefradil and temozolomide in patients with recurrent high-grade gliomas.
    Neuro-oncology, 2017, 06-01, Volume: 19, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Cal

2017
Timed sequential therapy of the selective T-type calcium channel blocker mibefradil and temozolomide in patients with recurrent high-grade gliomas.
    Neuro-oncology, 2017, 06-01, Volume: 19, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Cal

2017
Timed sequential therapy of the selective T-type calcium channel blocker mibefradil and temozolomide in patients with recurrent high-grade gliomas.
    Neuro-oncology, 2017, 06-01, Volume: 19, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Cal

2017
Tumor-treating fields plus chemotherapy versus chemotherapy alone for glioblastoma at first recurrence: a post hoc analysis of the EF-14 trial.
    CNS oncology, 2017, Volume: 6, Issue:3

    Topics: Adult; Aftercare; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Antineoplastic Agents,

2017
Tumor-treating fields plus chemotherapy versus chemotherapy alone for glioblastoma at first recurrence: a post hoc analysis of the EF-14 trial.
    CNS oncology, 2017, Volume: 6, Issue:3

    Topics: Adult; Aftercare; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Antineoplastic Agents,

2017
Tumor-treating fields plus chemotherapy versus chemotherapy alone for glioblastoma at first recurrence: a post hoc analysis of the EF-14 trial.
    CNS oncology, 2017, Volume: 6, Issue:3

    Topics: Adult; Aftercare; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Antineoplastic Agents,

2017
Tumor-treating fields plus chemotherapy versus chemotherapy alone for glioblastoma at first recurrence: a post hoc analysis of the EF-14 trial.
    CNS oncology, 2017, Volume: 6, Issue:3

    Topics: Adult; Aftercare; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Antineoplastic Agents,

2017
Tumor-treating fields plus chemotherapy versus chemotherapy alone for glioblastoma at first recurrence: a post hoc analysis of the EF-14 trial.
    CNS oncology, 2017, Volume: 6, Issue:3

    Topics: Adult; Aftercare; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Antineoplastic Agents,

2017
Tumor-treating fields plus chemotherapy versus chemotherapy alone for glioblastoma at first recurrence: a post hoc analysis of the EF-14 trial.
    CNS oncology, 2017, Volume: 6, Issue:3

    Topics: Adult; Aftercare; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Antineoplastic Agents,

2017
Tumor-treating fields plus chemotherapy versus chemotherapy alone for glioblastoma at first recurrence: a post hoc analysis of the EF-14 trial.
    CNS oncology, 2017, Volume: 6, Issue:3

    Topics: Adult; Aftercare; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Antineoplastic Agents,

2017
Tumor-treating fields plus chemotherapy versus chemotherapy alone for glioblastoma at first recurrence: a post hoc analysis of the EF-14 trial.
    CNS oncology, 2017, Volume: 6, Issue:3

    Topics: Adult; Aftercare; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Antineoplastic Agents,

2017
Tumor-treating fields plus chemotherapy versus chemotherapy alone for glioblastoma at first recurrence: a post hoc analysis of the EF-14 trial.
    CNS oncology, 2017, Volume: 6, Issue:3

    Topics: Adult; Aftercare; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Antineoplastic Agents,

2017
Tumor-treating fields plus chemotherapy versus chemotherapy alone for glioblastoma at first recurrence: a post hoc analysis of the EF-14 trial.
    CNS oncology, 2017, Volume: 6, Issue:3

    Topics: Adult; Aftercare; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Antineoplastic Agents,

2017
Tumor-treating fields plus chemotherapy versus chemotherapy alone for glioblastoma at first recurrence: a post hoc analysis of the EF-14 trial.
    CNS oncology, 2017, Volume: 6, Issue:3

    Topics: Adult; Aftercare; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Antineoplastic Agents,

2017
Tumor-treating fields plus chemotherapy versus chemotherapy alone for glioblastoma at first recurrence: a post hoc analysis of the EF-14 trial.
    CNS oncology, 2017, Volume: 6, Issue:3

    Topics: Adult; Aftercare; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Antineoplastic Agents,

2017
Biological basis and clinical study of glycogen synthase kinase- 3β-targeted therapy by drug repositioning for glioblastoma.
    Oncotarget, 2017, Apr-04, Volume: 8, Issue:14

    Topics: Aged; Animals; Antineoplastic Agents, Alkylating; Apoptosis; Biomarkers, Tumor; Brain Neoplasms; Cel

2017
Biological basis and clinical study of glycogen synthase kinase- 3β-targeted therapy by drug repositioning for glioblastoma.
    Oncotarget, 2017, Apr-04, Volume: 8, Issue:14

    Topics: Aged; Animals; Antineoplastic Agents, Alkylating; Apoptosis; Biomarkers, Tumor; Brain Neoplasms; Cel

2017
Biological basis and clinical study of glycogen synthase kinase- 3β-targeted therapy by drug repositioning for glioblastoma.
    Oncotarget, 2017, Apr-04, Volume: 8, Issue:14

    Topics: Aged; Animals; Antineoplastic Agents, Alkylating; Apoptosis; Biomarkers, Tumor; Brain Neoplasms; Cel

2017
Multicenter phase II study of temozolomide and myeloablative chemotherapy with autologous stem cell transplant for newly diagnosed anaplastic oligodendroglioma.
    Neuro-oncology, 2017, Oct-01, Volume: 19, Issue:10

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Dacarbazine; Dis

2017
Multicenter phase II study of temozolomide and myeloablative chemotherapy with autologous stem cell transplant for newly diagnosed anaplastic oligodendroglioma.
    Neuro-oncology, 2017, Oct-01, Volume: 19, Issue:10

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Dacarbazine; Dis

2017
Multicenter phase II study of temozolomide and myeloablative chemotherapy with autologous stem cell transplant for newly diagnosed anaplastic oligodendroglioma.
    Neuro-oncology, 2017, Oct-01, Volume: 19, Issue:10

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Dacarbazine; Dis

2017
A phase II trial of arsenic trioxide and temozolomide in combination with radiation therapy for patients with malignant gliomas.
    Journal of neuro-oncology, 2017, Volume: 133, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Arsenic Trioxide; Arsenicals; Bra

2017
A phase II trial of arsenic trioxide and temozolomide in combination with radiation therapy for patients with malignant gliomas.
    Journal of neuro-oncology, 2017, Volume: 133, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Arsenic Trioxide; Arsenicals; Bra

2017
A phase II trial of arsenic trioxide and temozolomide in combination with radiation therapy for patients with malignant gliomas.
    Journal of neuro-oncology, 2017, Volume: 133, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Arsenic Trioxide; Arsenicals; Bra

2017
Phase 1/2 Trial of 5-Fraction Stereotactic Radiosurgery With 5-mm Margins With Concurrent and Adjuvant Temozolomide in Newly Diagnosed Supratentorial Glioblastoma: Health-Related Quality of Life Results.
    International journal of radiation oncology, biology, physics, 2017, 05-01, Volume: 98, Issue:1

    Topics: Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Chem

2017
Phase 1/2 Trial of 5-Fraction Stereotactic Radiosurgery With 5-mm Margins With Concurrent and Adjuvant Temozolomide in Newly Diagnosed Supratentorial Glioblastoma: Health-Related Quality of Life Results.
    International journal of radiation oncology, biology, physics, 2017, 05-01, Volume: 98, Issue:1

    Topics: Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Chem

2017
Phase 1/2 Trial of 5-Fraction Stereotactic Radiosurgery With 5-mm Margins With Concurrent and Adjuvant Temozolomide in Newly Diagnosed Supratentorial Glioblastoma: Health-Related Quality of Life Results.
    International journal of radiation oncology, biology, physics, 2017, 05-01, Volume: 98, Issue:1

    Topics: Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Chem

2017
Report of safety of pulse dosing of lapatinib with temozolomide and radiation therapy for newly-diagnosed glioblastoma in a pilot phase II study.
    Journal of neuro-oncology, 2017, Volume: 134, Issue:2

    Topics: Adult; Aged; Antineoplastic Agents; Brain Neoplasms; Chemoradiotherapy; Dacarbazine; Drug Administra

2017
Report of safety of pulse dosing of lapatinib with temozolomide and radiation therapy for newly-diagnosed glioblastoma in a pilot phase II study.
    Journal of neuro-oncology, 2017, Volume: 134, Issue:2

    Topics: Adult; Aged; Antineoplastic Agents; Brain Neoplasms; Chemoradiotherapy; Dacarbazine; Drug Administra

2017
Report of safety of pulse dosing of lapatinib with temozolomide and radiation therapy for newly-diagnosed glioblastoma in a pilot phase II study.
    Journal of neuro-oncology, 2017, Volume: 134, Issue:2

    Topics: Adult; Aged; Antineoplastic Agents; Brain Neoplasms; Chemoradiotherapy; Dacarbazine; Drug Administra

2017
Phase II study of bi-weekly temozolomide plus bevacizumab for adult patients with recurrent glioblastoma.
    Cancer chemotherapy and pharmacology, 2017, Volume: 80, Issue:4

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bevacizu

2017
Phase II study of bi-weekly temozolomide plus bevacizumab for adult patients with recurrent glioblastoma.
    Cancer chemotherapy and pharmacology, 2017, Volume: 80, Issue:4

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bevacizu

2017
Phase II study of bi-weekly temozolomide plus bevacizumab for adult patients with recurrent glioblastoma.
    Cancer chemotherapy and pharmacology, 2017, Volume: 80, Issue:4

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bevacizu

2017
Rindopepimut with temozolomide for patients with newly diagnosed, EGFRvIII-expressing glioblastoma (ACT IV): a randomised, double-blind, international phase 3 trial.
    The Lancet. Oncology, 2017, Volume: 18, Issue:10

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Cancer Vaccines; Dacar

2017
Rindopepimut with temozolomide for patients with newly diagnosed, EGFRvIII-expressing glioblastoma (ACT IV): a randomised, double-blind, international phase 3 trial.
    The Lancet. Oncology, 2017, Volume: 18, Issue:10

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Cancer Vaccines; Dacar

2017
Rindopepimut with temozolomide for patients with newly diagnosed, EGFRvIII-expressing glioblastoma (ACT IV): a randomised, double-blind, international phase 3 trial.
    The Lancet. Oncology, 2017, Volume: 18, Issue:10

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Cancer Vaccines; Dacar

2017
Health-related quality of life, cognitive screening, and functional status in a randomized phase III trial (EF-14) of tumor treating fields with temozolomide compared to temozolomide alone in newly diagnosed glioblastoma.
    Journal of neuro-oncology, 2017, Volume: 135, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cognition; Combi

2017
Health-related quality of life, cognitive screening, and functional status in a randomized phase III trial (EF-14) of tumor treating fields with temozolomide compared to temozolomide alone in newly diagnosed glioblastoma.
    Journal of neuro-oncology, 2017, Volume: 135, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cognition; Combi

2017
Health-related quality of life, cognitive screening, and functional status in a randomized phase III trial (EF-14) of tumor treating fields with temozolomide compared to temozolomide alone in newly diagnosed glioblastoma.
    Journal of neuro-oncology, 2017, Volume: 135, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cognition; Combi

2017
Hypofractionated radiotherapy with simultaneous integrated boost (SIB) plus temozolomide in good prognosis patients with glioblastoma: a multicenter phase II study by the Brain Study Group of the Italian Association of Radiation Oncology (AIRO).
    La Radiologia medica, 2018, Volume: 123, Issue:1

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbaz

2018
Hypofractionated radiotherapy with simultaneous integrated boost (SIB) plus temozolomide in good prognosis patients with glioblastoma: a multicenter phase II study by the Brain Study Group of the Italian Association of Radiation Oncology (AIRO).
    La Radiologia medica, 2018, Volume: 123, Issue:1

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbaz

2018
Hypofractionated radiotherapy with simultaneous integrated boost (SIB) plus temozolomide in good prognosis patients with glioblastoma: a multicenter phase II study by the Brain Study Group of the Italian Association of Radiation Oncology (AIRO).
    La Radiologia medica, 2018, Volume: 123, Issue:1

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbaz

2018
Phase I/II trial of vorinostat combined with temozolomide and radiation therapy for newly diagnosed glioblastoma: results of Alliance N0874/ABTC 02.
    Neuro-oncology, 2018, 03-27, Volume: 20, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Che

2018
Phase I/II trial of vorinostat combined with temozolomide and radiation therapy for newly diagnosed glioblastoma: results of Alliance N0874/ABTC 02.
    Neuro-oncology, 2018, 03-27, Volume: 20, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Che

2018
Phase I/II trial of vorinostat combined with temozolomide and radiation therapy for newly diagnosed glioblastoma: results of Alliance N0874/ABTC 02.
    Neuro-oncology, 2018, 03-27, Volume: 20, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Che

2018
Radiologic progression of glioblastoma under therapy-an exploratory analysis of AVAglio.
    Neuro-oncology, 2018, 03-27, Volume: 20, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Biomark

2018
Radiologic progression of glioblastoma under therapy-an exploratory analysis of AVAglio.
    Neuro-oncology, 2018, 03-27, Volume: 20, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Biomark

2018
Radiologic progression of glioblastoma under therapy-an exploratory analysis of AVAglio.
    Neuro-oncology, 2018, 03-27, Volume: 20, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Biomark

2018
Safety, pharmacokinetics, and antitumor response of depatuxizumab mafodotin as monotherapy or in combination with temozolomide in patients with glioblastoma.
    Neuro-oncology, 2018, 05-18, Volume: 20, Issue:6

    Topics: Adult; Aged; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Brai

2018
Safety, pharmacokinetics, and antitumor response of depatuxizumab mafodotin as monotherapy or in combination with temozolomide in patients with glioblastoma.
    Neuro-oncology, 2018, 05-18, Volume: 20, Issue:6

    Topics: Adult; Aged; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Brai

2018
Safety, pharmacokinetics, and antitumor response of depatuxizumab mafodotin as monotherapy or in combination with temozolomide in patients with glioblastoma.
    Neuro-oncology, 2018, 05-18, Volume: 20, Issue:6

    Topics: Adult; Aged; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Brai

2018
Safety, pharmacokinetics, and antitumor response of depatuxizumab mafodotin as monotherapy or in combination with temozolomide in patients with glioblastoma.
    Neuro-oncology, 2018, 05-18, Volume: 20, Issue:6

    Topics: Adult; Aged; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Brai

2018
Safety, pharmacokinetics, and antitumor response of depatuxizumab mafodotin as monotherapy or in combination with temozolomide in patients with glioblastoma.
    Neuro-oncology, 2018, 05-18, Volume: 20, Issue:6

    Topics: Adult; Aged; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Brai

2018
Safety, pharmacokinetics, and antitumor response of depatuxizumab mafodotin as monotherapy or in combination with temozolomide in patients with glioblastoma.
    Neuro-oncology, 2018, 05-18, Volume: 20, Issue:6

    Topics: Adult; Aged; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Brai

2018
Safety, pharmacokinetics, and antitumor response of depatuxizumab mafodotin as monotherapy or in combination with temozolomide in patients with glioblastoma.
    Neuro-oncology, 2018, 05-18, Volume: 20, Issue:6

    Topics: Adult; Aged; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Brai

2018
Safety, pharmacokinetics, and antitumor response of depatuxizumab mafodotin as monotherapy or in combination with temozolomide in patients with glioblastoma.
    Neuro-oncology, 2018, 05-18, Volume: 20, Issue:6

    Topics: Adult; Aged; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Brai

2018
Safety, pharmacokinetics, and antitumor response of depatuxizumab mafodotin as monotherapy or in combination with temozolomide in patients with glioblastoma.
    Neuro-oncology, 2018, 05-18, Volume: 20, Issue:6

    Topics: Adult; Aged; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Brai

2018
Safety, pharmacokinetics, and antitumor response of depatuxizumab mafodotin as monotherapy or in combination with temozolomide in patients with glioblastoma.
    Neuro-oncology, 2018, 05-18, Volume: 20, Issue:6

    Topics: Adult; Aged; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Brai

2018
Safety, pharmacokinetics, and antitumor response of depatuxizumab mafodotin as monotherapy or in combination with temozolomide in patients with glioblastoma.
    Neuro-oncology, 2018, 05-18, Volume: 20, Issue:6

    Topics: Adult; Aged; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Brai

2018
Safety, pharmacokinetics, and antitumor response of depatuxizumab mafodotin as monotherapy or in combination with temozolomide in patients with glioblastoma.
    Neuro-oncology, 2018, 05-18, Volume: 20, Issue:6

    Topics: Adult; Aged; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Brai

2018
Investigating the Effect of Reirradiation or Systemic Therapy in Patients With Glioblastoma After Tumor Progression: A Secondary Analysis of NRG Oncology/Radiation Therapy Oncology Group Trial 0525.
    International journal of radiation oncology, biology, physics, 2018, 01-01, Volume: 100, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Cranial Irradiation; Dacarbaz

2018
Investigating the Effect of Reirradiation or Systemic Therapy in Patients With Glioblastoma After Tumor Progression: A Secondary Analysis of NRG Oncology/Radiation Therapy Oncology Group Trial 0525.
    International journal of radiation oncology, biology, physics, 2018, 01-01, Volume: 100, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Cranial Irradiation; Dacarbaz

2018
Investigating the Effect of Reirradiation or Systemic Therapy in Patients With Glioblastoma After Tumor Progression: A Secondary Analysis of NRG Oncology/Radiation Therapy Oncology Group Trial 0525.
    International journal of radiation oncology, biology, physics, 2018, 01-01, Volume: 100, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Cranial Irradiation; Dacarbaz

2018
Quality of life in the GLARIUS trial randomizing bevacizumab/irinotecan versus temozolomide in newly diagnosed, MGMT-nonmethylated glioblastoma.
    Neuro-oncology, 2018, 06-18, Volume: 20, Issue:7

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Brain Neoplasms; DNA Methy

2018
Quality of life in the GLARIUS trial randomizing bevacizumab/irinotecan versus temozolomide in newly diagnosed, MGMT-nonmethylated glioblastoma.
    Neuro-oncology, 2018, 06-18, Volume: 20, Issue:7

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Brain Neoplasms; DNA Methy

2018
Quality of life in the GLARIUS trial randomizing bevacizumab/irinotecan versus temozolomide in newly diagnosed, MGMT-nonmethylated glioblastoma.
    Neuro-oncology, 2018, 06-18, Volume: 20, Issue:7

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Brain Neoplasms; DNA Methy

2018
A randomized phase II study of everolimus in combination with chemoradiation in newly diagnosed glioblastoma: results of NRG Oncology RTOG 0913.
    Neuro-oncology, 2018, 04-09, Volume: 20, Issue:5

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Chemoradio

2018
A randomized phase II study of everolimus in combination with chemoradiation in newly diagnosed glioblastoma: results of NRG Oncology RTOG 0913.
    Neuro-oncology, 2018, 04-09, Volume: 20, Issue:5

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Chemoradio

2018
A randomized phase II study of everolimus in combination with chemoradiation in newly diagnosed glioblastoma: results of NRG Oncology RTOG 0913.
    Neuro-oncology, 2018, 04-09, Volume: 20, Issue:5

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Chemoradio

2018
Radiotherapy plus temozolomide in elderly patients with glioblastoma: a "real-life" report.
    Radiation oncology (London, England), 2017, Dec-06, Volume: 12, Issue:1

    Topics: Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Daca

2017
Radiotherapy plus temozolomide in elderly patients with glioblastoma: a "real-life" report.
    Radiation oncology (London, England), 2017, Dec-06, Volume: 12, Issue:1

    Topics: Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Daca

2017
Radiotherapy plus temozolomide in elderly patients with glioblastoma: a "real-life" report.
    Radiation oncology (London, England), 2017, Dec-06, Volume: 12, Issue:1

    Topics: Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Daca

2017
Efficacy and safety of temozolomide plus whole-brain radiotherapy in the treatment of intracranial metastases.
    Journal of cancer research and therapeutics, 2017, Volume: 13, Issue:5

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain; Brain Neoplasms; Chemoradiotherapy; Cranial I

2017
Efficacy and safety of temozolomide plus whole-brain radiotherapy in the treatment of intracranial metastases.
    Journal of cancer research and therapeutics, 2017, Volume: 13, Issue:5

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain; Brain Neoplasms; Chemoradiotherapy; Cranial I

2017
Efficacy and safety of temozolomide plus whole-brain radiotherapy in the treatment of intracranial metastases.
    Journal of cancer research and therapeutics, 2017, Volume: 13, Issue:5

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain; Brain Neoplasms; Chemoradiotherapy; Cranial I

2017
Phase I/II trial of vorinostat, bevacizumab, and daily temozolomide for recurrent malignant gliomas.
    Journal of neuro-oncology, 2018, Volume: 137, Issue:2

    Topics: Adult; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Brain Neo

2018
Phase I/II trial of vorinostat, bevacizumab, and daily temozolomide for recurrent malignant gliomas.
    Journal of neuro-oncology, 2018, Volume: 137, Issue:2

    Topics: Adult; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Brain Neo

2018
Phase I/II trial of vorinostat, bevacizumab, and daily temozolomide for recurrent malignant gliomas.
    Journal of neuro-oncology, 2018, Volume: 137, Issue:2

    Topics: Adult; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Brain Neo

2018
The effect of an adenosine A
    Fluids and barriers of the CNS, 2018, Jan-15, Volume: 15, Issue:1

    Topics: Adenosine A2 Receptor Agonists; Administration, Intravenous; Administration, Oral; Adult; Aged; Anti

2018
The effect of an adenosine A
    Fluids and barriers of the CNS, 2018, Jan-15, Volume: 15, Issue:1

    Topics: Adenosine A2 Receptor Agonists; Administration, Intravenous; Administration, Oral; Adult; Aged; Anti

2018
The effect of an adenosine A
    Fluids and barriers of the CNS, 2018, Jan-15, Volume: 15, Issue:1

    Topics: Adenosine A2 Receptor Agonists; Administration, Intravenous; Administration, Oral; Adult; Aged; Anti

2018
The DNA methylome of DDR genes and benefit from RT or TMZ in IDH mutant low-grade glioma treated in EORTC 22033.
    Acta neuropathologica, 2018, Volume: 135, Issue:4

    Topics: Adult; Antineoplastic Agents, Alkylating; Brain Neoplasms; CpG Islands; Discoidin Domain Receptors;

2018
The DNA methylome of DDR genes and benefit from RT or TMZ in IDH mutant low-grade glioma treated in EORTC 22033.
    Acta neuropathologica, 2018, Volume: 135, Issue:4

    Topics: Adult; Antineoplastic Agents, Alkylating; Brain Neoplasms; CpG Islands; Discoidin Domain Receptors;

2018
The DNA methylome of DDR genes and benefit from RT or TMZ in IDH mutant low-grade glioma treated in EORTC 22033.
    Acta neuropathologica, 2018, Volume: 135, Issue:4

    Topics: Adult; Antineoplastic Agents, Alkylating; Brain Neoplasms; CpG Islands; Discoidin Domain Receptors;

2018
Final results of a phase I dose-escalation, dose-expansion study of adding disulfiram with or without copper to adjuvant temozolomide for newly diagnosed glioblastoma.
    Journal of neuro-oncology, 2018, Volume: 138, Issue:1

    Topics: Adjuvants, Immunologic; Adult; Aged; Antineoplastic Agents; Brain Neoplasms; Cohort Studies; Copper;

2018
Final results of a phase I dose-escalation, dose-expansion study of adding disulfiram with or without copper to adjuvant temozolomide for newly diagnosed glioblastoma.
    Journal of neuro-oncology, 2018, Volume: 138, Issue:1

    Topics: Adjuvants, Immunologic; Adult; Aged; Antineoplastic Agents; Brain Neoplasms; Cohort Studies; Copper;

2018
Final results of a phase I dose-escalation, dose-expansion study of adding disulfiram with or without copper to adjuvant temozolomide for newly diagnosed glioblastoma.
    Journal of neuro-oncology, 2018, Volume: 138, Issue:1

    Topics: Adjuvants, Immunologic; Adult; Aged; Antineoplastic Agents; Brain Neoplasms; Cohort Studies; Copper;

2018
Clinical Trial of MGMT(P140K) Gene Therapy in the Treatment of Pediatric Patients with Brain Tumors.
    Human gene therapy, 2018, Volume: 29, Issue:8

    Topics: Brain Neoplasms; Child; DNA Modification Methylases; DNA Repair Enzymes; Drug Resistance, Neoplasm;

2018
Clinical Trial of MGMT(P140K) Gene Therapy in the Treatment of Pediatric Patients with Brain Tumors.
    Human gene therapy, 2018, Volume: 29, Issue:8

    Topics: Brain Neoplasms; Child; DNA Modification Methylases; DNA Repair Enzymes; Drug Resistance, Neoplasm;

2018
Clinical Trial of MGMT(P140K) Gene Therapy in the Treatment of Pediatric Patients with Brain Tumors.
    Human gene therapy, 2018, Volume: 29, Issue:8

    Topics: Brain Neoplasms; Child; DNA Modification Methylases; DNA Repair Enzymes; Drug Resistance, Neoplasm;

2018
Influence of Treatment With Tumor-Treating Fields on Health-Related Quality of Life of Patients With Newly Diagnosed Glioblastoma: A Secondary Analysis of a Randomized Clinical Trial.
    JAMA oncology, 2018, Apr-01, Volume: 4, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Brain Neoplasms; Chemoradiotherapy; Combined Modality Therapy; Cytor

2018
Influence of Treatment With Tumor-Treating Fields on Health-Related Quality of Life of Patients With Newly Diagnosed Glioblastoma: A Secondary Analysis of a Randomized Clinical Trial.
    JAMA oncology, 2018, Apr-01, Volume: 4, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Brain Neoplasms; Chemoradiotherapy; Combined Modality Therapy; Cytor

2018
Influence of Treatment With Tumor-Treating Fields on Health-Related Quality of Life of Patients With Newly Diagnosed Glioblastoma: A Secondary Analysis of a Randomized Clinical Trial.
    JAMA oncology, 2018, Apr-01, Volume: 4, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Brain Neoplasms; Chemoradiotherapy; Combined Modality Therapy; Cytor

2018
Influence of Treatment With Tumor-Treating Fields on Health-Related Quality of Life of Patients With Newly Diagnosed Glioblastoma: A Secondary Analysis of a Randomized Clinical Trial.
    JAMA oncology, 2018, Apr-01, Volume: 4, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Brain Neoplasms; Chemoradiotherapy; Combined Modality Therapy; Cytor

2018
Influence of Treatment With Tumor-Treating Fields on Health-Related Quality of Life of Patients With Newly Diagnosed Glioblastoma: A Secondary Analysis of a Randomized Clinical Trial.
    JAMA oncology, 2018, Apr-01, Volume: 4, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Brain Neoplasms; Chemoradiotherapy; Combined Modality Therapy; Cytor

2018
Influence of Treatment With Tumor-Treating Fields on Health-Related Quality of Life of Patients With Newly Diagnosed Glioblastoma: A Secondary Analysis of a Randomized Clinical Trial.
    JAMA oncology, 2018, Apr-01, Volume: 4, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Brain Neoplasms; Chemoradiotherapy; Combined Modality Therapy; Cytor

2018
Influence of Treatment With Tumor-Treating Fields on Health-Related Quality of Life of Patients With Newly Diagnosed Glioblastoma: A Secondary Analysis of a Randomized Clinical Trial.
    JAMA oncology, 2018, Apr-01, Volume: 4, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Brain Neoplasms; Chemoradiotherapy; Combined Modality Therapy; Cytor

2018
Influence of Treatment With Tumor-Treating Fields on Health-Related Quality of Life of Patients With Newly Diagnosed Glioblastoma: A Secondary Analysis of a Randomized Clinical Trial.
    JAMA oncology, 2018, Apr-01, Volume: 4, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Brain Neoplasms; Chemoradiotherapy; Combined Modality Therapy; Cytor

2018
Influence of Treatment With Tumor-Treating Fields on Health-Related Quality of Life of Patients With Newly Diagnosed Glioblastoma: A Secondary Analysis of a Randomized Clinical Trial.
    JAMA oncology, 2018, Apr-01, Volume: 4, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Brain Neoplasms; Chemoradiotherapy; Combined Modality Therapy; Cytor

2018
Influence of Treatment With Tumor-Treating Fields on Health-Related Quality of Life of Patients With Newly Diagnosed Glioblastoma: A Secondary Analysis of a Randomized Clinical Trial.
    JAMA oncology, 2018, Apr-01, Volume: 4, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Brain Neoplasms; Chemoradiotherapy; Combined Modality Therapy; Cytor

2018
Influence of Treatment With Tumor-Treating Fields on Health-Related Quality of Life of Patients With Newly Diagnosed Glioblastoma: A Secondary Analysis of a Randomized Clinical Trial.
    JAMA oncology, 2018, Apr-01, Volume: 4, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Brain Neoplasms; Chemoradiotherapy; Combined Modality Therapy; Cytor

2018
Influence of Treatment With Tumor-Treating Fields on Health-Related Quality of Life of Patients With Newly Diagnosed Glioblastoma: A Secondary Analysis of a Randomized Clinical Trial.
    JAMA oncology, 2018, Apr-01, Volume: 4, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Brain Neoplasms; Chemoradiotherapy; Combined Modality Therapy; Cytor

2018
Influence of Treatment With Tumor-Treating Fields on Health-Related Quality of Life of Patients With Newly Diagnosed Glioblastoma: A Secondary Analysis of a Randomized Clinical Trial.
    JAMA oncology, 2018, Apr-01, Volume: 4, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Brain Neoplasms; Chemoradiotherapy; Combined Modality Therapy; Cytor

2018
Influence of Treatment With Tumor-Treating Fields on Health-Related Quality of Life of Patients With Newly Diagnosed Glioblastoma: A Secondary Analysis of a Randomized Clinical Trial.
    JAMA oncology, 2018, Apr-01, Volume: 4, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Brain Neoplasms; Chemoradiotherapy; Combined Modality Therapy; Cytor

2018
Influence of Treatment With Tumor-Treating Fields on Health-Related Quality of Life of Patients With Newly Diagnosed Glioblastoma: A Secondary Analysis of a Randomized Clinical Trial.
    JAMA oncology, 2018, Apr-01, Volume: 4, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Brain Neoplasms; Chemoradiotherapy; Combined Modality Therapy; Cytor

2018
Influence of Treatment With Tumor-Treating Fields on Health-Related Quality of Life of Patients With Newly Diagnosed Glioblastoma: A Secondary Analysis of a Randomized Clinical Trial.
    JAMA oncology, 2018, Apr-01, Volume: 4, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Brain Neoplasms; Chemoradiotherapy; Combined Modality Therapy; Cytor

2018
Influence of Treatment With Tumor-Treating Fields on Health-Related Quality of Life of Patients With Newly Diagnosed Glioblastoma: A Secondary Analysis of a Randomized Clinical Trial.
    JAMA oncology, 2018, Apr-01, Volume: 4, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Brain Neoplasms; Chemoradiotherapy; Combined Modality Therapy; Cytor

2018
Influence of Treatment With Tumor-Treating Fields on Health-Related Quality of Life of Patients With Newly Diagnosed Glioblastoma: A Secondary Analysis of a Randomized Clinical Trial.
    JAMA oncology, 2018, Apr-01, Volume: 4, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Brain Neoplasms; Chemoradiotherapy; Combined Modality Therapy; Cytor

2018
Influence of Treatment With Tumor-Treating Fields on Health-Related Quality of Life of Patients With Newly Diagnosed Glioblastoma: A Secondary Analysis of a Randomized Clinical Trial.
    JAMA oncology, 2018, Apr-01, Volume: 4, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Brain Neoplasms; Chemoradiotherapy; Combined Modality Therapy; Cytor

2018
Influence of Treatment With Tumor-Treating Fields on Health-Related Quality of Life of Patients With Newly Diagnosed Glioblastoma: A Secondary Analysis of a Randomized Clinical Trial.
    JAMA oncology, 2018, Apr-01, Volume: 4, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Brain Neoplasms; Chemoradiotherapy; Combined Modality Therapy; Cytor

2018
Influence of Treatment With Tumor-Treating Fields on Health-Related Quality of Life of Patients With Newly Diagnosed Glioblastoma: A Secondary Analysis of a Randomized Clinical Trial.
    JAMA oncology, 2018, Apr-01, Volume: 4, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Brain Neoplasms; Chemoradiotherapy; Combined Modality Therapy; Cytor

2018
Influence of Treatment With Tumor-Treating Fields on Health-Related Quality of Life of Patients With Newly Diagnosed Glioblastoma: A Secondary Analysis of a Randomized Clinical Trial.
    JAMA oncology, 2018, Apr-01, Volume: 4, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Brain Neoplasms; Chemoradiotherapy; Combined Modality Therapy; Cytor

2018
Influence of Treatment With Tumor-Treating Fields on Health-Related Quality of Life of Patients With Newly Diagnosed Glioblastoma: A Secondary Analysis of a Randomized Clinical Trial.
    JAMA oncology, 2018, Apr-01, Volume: 4, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Brain Neoplasms; Chemoradiotherapy; Combined Modality Therapy; Cytor

2018
Influence of Treatment With Tumor-Treating Fields on Health-Related Quality of Life of Patients With Newly Diagnosed Glioblastoma: A Secondary Analysis of a Randomized Clinical Trial.
    JAMA oncology, 2018, Apr-01, Volume: 4, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Brain Neoplasms; Chemoradiotherapy; Combined Modality Therapy; Cytor

2018
Influence of Treatment With Tumor-Treating Fields on Health-Related Quality of Life of Patients With Newly Diagnosed Glioblastoma: A Secondary Analysis of a Randomized Clinical Trial.
    JAMA oncology, 2018, Apr-01, Volume: 4, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Brain Neoplasms; Chemoradiotherapy; Combined Modality Therapy; Cytor

2018
Influence of Treatment With Tumor-Treating Fields on Health-Related Quality of Life of Patients With Newly Diagnosed Glioblastoma: A Secondary Analysis of a Randomized Clinical Trial.
    JAMA oncology, 2018, Apr-01, Volume: 4, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Brain Neoplasms; Chemoradiotherapy; Combined Modality Therapy; Cytor

2018
Influence of Treatment With Tumor-Treating Fields on Health-Related Quality of Life of Patients With Newly Diagnosed Glioblastoma: A Secondary Analysis of a Randomized Clinical Trial.
    JAMA oncology, 2018, Apr-01, Volume: 4, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Brain Neoplasms; Chemoradiotherapy; Combined Modality Therapy; Cytor

2018
Influence of Treatment With Tumor-Treating Fields on Health-Related Quality of Life of Patients With Newly Diagnosed Glioblastoma: A Secondary Analysis of a Randomized Clinical Trial.
    JAMA oncology, 2018, Apr-01, Volume: 4, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Brain Neoplasms; Chemoradiotherapy; Combined Modality Therapy; Cytor

2018
Influence of Treatment With Tumor-Treating Fields on Health-Related Quality of Life of Patients With Newly Diagnosed Glioblastoma: A Secondary Analysis of a Randomized Clinical Trial.
    JAMA oncology, 2018, Apr-01, Volume: 4, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Brain Neoplasms; Chemoradiotherapy; Combined Modality Therapy; Cytor

2018
Influence of Treatment With Tumor-Treating Fields on Health-Related Quality of Life of Patients With Newly Diagnosed Glioblastoma: A Secondary Analysis of a Randomized Clinical Trial.
    JAMA oncology, 2018, Apr-01, Volume: 4, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Brain Neoplasms; Chemoradiotherapy; Combined Modality Therapy; Cytor

2018
Influence of Treatment With Tumor-Treating Fields on Health-Related Quality of Life of Patients With Newly Diagnosed Glioblastoma: A Secondary Analysis of a Randomized Clinical Trial.
    JAMA oncology, 2018, Apr-01, Volume: 4, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Brain Neoplasms; Chemoradiotherapy; Combined Modality Therapy; Cytor

2018
Influence of Treatment With Tumor-Treating Fields on Health-Related Quality of Life of Patients With Newly Diagnosed Glioblastoma: A Secondary Analysis of a Randomized Clinical Trial.
    JAMA oncology, 2018, Apr-01, Volume: 4, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Brain Neoplasms; Chemoradiotherapy; Combined Modality Therapy; Cytor

2018
Influence of Treatment With Tumor-Treating Fields on Health-Related Quality of Life of Patients With Newly Diagnosed Glioblastoma: A Secondary Analysis of a Randomized Clinical Trial.
    JAMA oncology, 2018, Apr-01, Volume: 4, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Brain Neoplasms; Chemoradiotherapy; Combined Modality Therapy; Cytor

2018
Influence of Treatment With Tumor-Treating Fields on Health-Related Quality of Life of Patients With Newly Diagnosed Glioblastoma: A Secondary Analysis of a Randomized Clinical Trial.
    JAMA oncology, 2018, Apr-01, Volume: 4, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Brain Neoplasms; Chemoradiotherapy; Combined Modality Therapy; Cytor

2018
Influence of Treatment With Tumor-Treating Fields on Health-Related Quality of Life of Patients With Newly Diagnosed Glioblastoma: A Secondary Analysis of a Randomized Clinical Trial.
    JAMA oncology, 2018, Apr-01, Volume: 4, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Brain Neoplasms; Chemoradiotherapy; Combined Modality Therapy; Cytor

2018
Influence of Treatment With Tumor-Treating Fields on Health-Related Quality of Life of Patients With Newly Diagnosed Glioblastoma: A Secondary Analysis of a Randomized Clinical Trial.
    JAMA oncology, 2018, Apr-01, Volume: 4, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Brain Neoplasms; Chemoradiotherapy; Combined Modality Therapy; Cytor

2018
Influence of Treatment With Tumor-Treating Fields on Health-Related Quality of Life of Patients With Newly Diagnosed Glioblastoma: A Secondary Analysis of a Randomized Clinical Trial.
    JAMA oncology, 2018, Apr-01, Volume: 4, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Brain Neoplasms; Chemoradiotherapy; Combined Modality Therapy; Cytor

2018
Influence of Treatment With Tumor-Treating Fields on Health-Related Quality of Life of Patients With Newly Diagnosed Glioblastoma: A Secondary Analysis of a Randomized Clinical Trial.
    JAMA oncology, 2018, Apr-01, Volume: 4, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Brain Neoplasms; Chemoradiotherapy; Combined Modality Therapy; Cytor

2018
Influence of Treatment With Tumor-Treating Fields on Health-Related Quality of Life of Patients With Newly Diagnosed Glioblastoma: A Secondary Analysis of a Randomized Clinical Trial.
    JAMA oncology, 2018, Apr-01, Volume: 4, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Brain Neoplasms; Chemoradiotherapy; Combined Modality Therapy; Cytor

2018
Influence of Treatment With Tumor-Treating Fields on Health-Related Quality of Life of Patients With Newly Diagnosed Glioblastoma: A Secondary Analysis of a Randomized Clinical Trial.
    JAMA oncology, 2018, Apr-01, Volume: 4, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Brain Neoplasms; Chemoradiotherapy; Combined Modality Therapy; Cytor

2018
Influence of Treatment With Tumor-Treating Fields on Health-Related Quality of Life of Patients With Newly Diagnosed Glioblastoma: A Secondary Analysis of a Randomized Clinical Trial.
    JAMA oncology, 2018, Apr-01, Volume: 4, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Brain Neoplasms; Chemoradiotherapy; Combined Modality Therapy; Cytor

2018
Influence of Treatment With Tumor-Treating Fields on Health-Related Quality of Life of Patients With Newly Diagnosed Glioblastoma: A Secondary Analysis of a Randomized Clinical Trial.
    JAMA oncology, 2018, Apr-01, Volume: 4, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Brain Neoplasms; Chemoradiotherapy; Combined Modality Therapy; Cytor

2018
Influence of Treatment With Tumor-Treating Fields on Health-Related Quality of Life of Patients With Newly Diagnosed Glioblastoma: A Secondary Analysis of a Randomized Clinical Trial.
    JAMA oncology, 2018, Apr-01, Volume: 4, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Brain Neoplasms; Chemoradiotherapy; Combined Modality Therapy; Cytor

2018
Influence of Treatment With Tumor-Treating Fields on Health-Related Quality of Life of Patients With Newly Diagnosed Glioblastoma: A Secondary Analysis of a Randomized Clinical Trial.
    JAMA oncology, 2018, Apr-01, Volume: 4, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Brain Neoplasms; Chemoradiotherapy; Combined Modality Therapy; Cytor

2018
Influence of Treatment With Tumor-Treating Fields on Health-Related Quality of Life of Patients With Newly Diagnosed Glioblastoma: A Secondary Analysis of a Randomized Clinical Trial.
    JAMA oncology, 2018, Apr-01, Volume: 4, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Brain Neoplasms; Chemoradiotherapy; Combined Modality Therapy; Cytor

2018
Influence of Treatment With Tumor-Treating Fields on Health-Related Quality of Life of Patients With Newly Diagnosed Glioblastoma: A Secondary Analysis of a Randomized Clinical Trial.
    JAMA oncology, 2018, Apr-01, Volume: 4, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Brain Neoplasms; Chemoradiotherapy; Combined Modality Therapy; Cytor

2018
Influence of Treatment With Tumor-Treating Fields on Health-Related Quality of Life of Patients With Newly Diagnosed Glioblastoma: A Secondary Analysis of a Randomized Clinical Trial.
    JAMA oncology, 2018, Apr-01, Volume: 4, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Brain Neoplasms; Chemoradiotherapy; Combined Modality Therapy; Cytor

2018
Influence of Treatment With Tumor-Treating Fields on Health-Related Quality of Life of Patients With Newly Diagnosed Glioblastoma: A Secondary Analysis of a Randomized Clinical Trial.
    JAMA oncology, 2018, Apr-01, Volume: 4, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Brain Neoplasms; Chemoradiotherapy; Combined Modality Therapy; Cytor

2018
Influence of Treatment With Tumor-Treating Fields on Health-Related Quality of Life of Patients With Newly Diagnosed Glioblastoma: A Secondary Analysis of a Randomized Clinical Trial.
    JAMA oncology, 2018, Apr-01, Volume: 4, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Brain Neoplasms; Chemoradiotherapy; Combined Modality Therapy; Cytor

2018
Influence of Treatment With Tumor-Treating Fields on Health-Related Quality of Life of Patients With Newly Diagnosed Glioblastoma: A Secondary Analysis of a Randomized Clinical Trial.
    JAMA oncology, 2018, Apr-01, Volume: 4, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Brain Neoplasms; Chemoradiotherapy; Combined Modality Therapy; Cytor

2018
Influence of Treatment With Tumor-Treating Fields on Health-Related Quality of Life of Patients With Newly Diagnosed Glioblastoma: A Secondary Analysis of a Randomized Clinical Trial.
    JAMA oncology, 2018, Apr-01, Volume: 4, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Brain Neoplasms; Chemoradiotherapy; Combined Modality Therapy; Cytor

2018
Influence of Treatment With Tumor-Treating Fields on Health-Related Quality of Life of Patients With Newly Diagnosed Glioblastoma: A Secondary Analysis of a Randomized Clinical Trial.
    JAMA oncology, 2018, Apr-01, Volume: 4, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Brain Neoplasms; Chemoradiotherapy; Combined Modality Therapy; Cytor

2018
Influence of Treatment With Tumor-Treating Fields on Health-Related Quality of Life of Patients With Newly Diagnosed Glioblastoma: A Secondary Analysis of a Randomized Clinical Trial.
    JAMA oncology, 2018, Apr-01, Volume: 4, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Brain Neoplasms; Chemoradiotherapy; Combined Modality Therapy; Cytor

2018
Influence of Treatment With Tumor-Treating Fields on Health-Related Quality of Life of Patients With Newly Diagnosed Glioblastoma: A Secondary Analysis of a Randomized Clinical Trial.
    JAMA oncology, 2018, Apr-01, Volume: 4, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Brain Neoplasms; Chemoradiotherapy; Combined Modality Therapy; Cytor

2018
Influence of Treatment With Tumor-Treating Fields on Health-Related Quality of Life of Patients With Newly Diagnosed Glioblastoma: A Secondary Analysis of a Randomized Clinical Trial.
    JAMA oncology, 2018, Apr-01, Volume: 4, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Brain Neoplasms; Chemoradiotherapy; Combined Modality Therapy; Cytor

2018
Influence of Treatment With Tumor-Treating Fields on Health-Related Quality of Life of Patients With Newly Diagnosed Glioblastoma: A Secondary Analysis of a Randomized Clinical Trial.
    JAMA oncology, 2018, Apr-01, Volume: 4, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Brain Neoplasms; Chemoradiotherapy; Combined Modality Therapy; Cytor

2018
Influence of Treatment With Tumor-Treating Fields on Health-Related Quality of Life of Patients With Newly Diagnosed Glioblastoma: A Secondary Analysis of a Randomized Clinical Trial.
    JAMA oncology, 2018, Apr-01, Volume: 4, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Brain Neoplasms; Chemoradiotherapy; Combined Modality Therapy; Cytor

2018
Influence of Treatment With Tumor-Treating Fields on Health-Related Quality of Life of Patients With Newly Diagnosed Glioblastoma: A Secondary Analysis of a Randomized Clinical Trial.
    JAMA oncology, 2018, Apr-01, Volume: 4, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Brain Neoplasms; Chemoradiotherapy; Combined Modality Therapy; Cytor

2018
Influence of Treatment With Tumor-Treating Fields on Health-Related Quality of Life of Patients With Newly Diagnosed Glioblastoma: A Secondary Analysis of a Randomized Clinical Trial.
    JAMA oncology, 2018, Apr-01, Volume: 4, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Brain Neoplasms; Chemoradiotherapy; Combined Modality Therapy; Cytor

2018
Influence of Treatment With Tumor-Treating Fields on Health-Related Quality of Life of Patients With Newly Diagnosed Glioblastoma: A Secondary Analysis of a Randomized Clinical Trial.
    JAMA oncology, 2018, Apr-01, Volume: 4, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Brain Neoplasms; Chemoradiotherapy; Combined Modality Therapy; Cytor

2018
Influence of Treatment With Tumor-Treating Fields on Health-Related Quality of Life of Patients With Newly Diagnosed Glioblastoma: A Secondary Analysis of a Randomized Clinical Trial.
    JAMA oncology, 2018, Apr-01, Volume: 4, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Brain Neoplasms; Chemoradiotherapy; Combined Modality Therapy; Cytor

2018
Influence of Treatment With Tumor-Treating Fields on Health-Related Quality of Life of Patients With Newly Diagnosed Glioblastoma: A Secondary Analysis of a Randomized Clinical Trial.
    JAMA oncology, 2018, Apr-01, Volume: 4, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Brain Neoplasms; Chemoradiotherapy; Combined Modality Therapy; Cytor

2018
Influence of Treatment With Tumor-Treating Fields on Health-Related Quality of Life of Patients With Newly Diagnosed Glioblastoma: A Secondary Analysis of a Randomized Clinical Trial.
    JAMA oncology, 2018, Apr-01, Volume: 4, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Brain Neoplasms; Chemoradiotherapy; Combined Modality Therapy; Cytor

2018
Influence of Treatment With Tumor-Treating Fields on Health-Related Quality of Life of Patients With Newly Diagnosed Glioblastoma: A Secondary Analysis of a Randomized Clinical Trial.
    JAMA oncology, 2018, Apr-01, Volume: 4, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Brain Neoplasms; Chemoradiotherapy; Combined Modality Therapy; Cytor

2018
Influence of Treatment With Tumor-Treating Fields on Health-Related Quality of Life of Patients With Newly Diagnosed Glioblastoma: A Secondary Analysis of a Randomized Clinical Trial.
    JAMA oncology, 2018, Apr-01, Volume: 4, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Brain Neoplasms; Chemoradiotherapy; Combined Modality Therapy; Cytor

2018
Influence of Treatment With Tumor-Treating Fields on Health-Related Quality of Life of Patients With Newly Diagnosed Glioblastoma: A Secondary Analysis of a Randomized Clinical Trial.
    JAMA oncology, 2018, Apr-01, Volume: 4, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Brain Neoplasms; Chemoradiotherapy; Combined Modality Therapy; Cytor

2018
Influence of Treatment With Tumor-Treating Fields on Health-Related Quality of Life of Patients With Newly Diagnosed Glioblastoma: A Secondary Analysis of a Randomized Clinical Trial.
    JAMA oncology, 2018, Apr-01, Volume: 4, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Brain Neoplasms; Chemoradiotherapy; Combined Modality Therapy; Cytor

2018
Influence of Treatment With Tumor-Treating Fields on Health-Related Quality of Life of Patients With Newly Diagnosed Glioblastoma: A Secondary Analysis of a Randomized Clinical Trial.
    JAMA oncology, 2018, Apr-01, Volume: 4, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Brain Neoplasms; Chemoradiotherapy; Combined Modality Therapy; Cytor

2018
Influence of Treatment With Tumor-Treating Fields on Health-Related Quality of Life of Patients With Newly Diagnosed Glioblastoma: A Secondary Analysis of a Randomized Clinical Trial.
    JAMA oncology, 2018, Apr-01, Volume: 4, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Brain Neoplasms; Chemoradiotherapy; Combined Modality Therapy; Cytor

2018
Influence of Treatment With Tumor-Treating Fields on Health-Related Quality of Life of Patients With Newly Diagnosed Glioblastoma: A Secondary Analysis of a Randomized Clinical Trial.
    JAMA oncology, 2018, Apr-01, Volume: 4, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Brain Neoplasms; Chemoradiotherapy; Combined Modality Therapy; Cytor

2018
Influence of Treatment With Tumor-Treating Fields on Health-Related Quality of Life of Patients With Newly Diagnosed Glioblastoma: A Secondary Analysis of a Randomized Clinical Trial.
    JAMA oncology, 2018, Apr-01, Volume: 4, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Brain Neoplasms; Chemoradiotherapy; Combined Modality Therapy; Cytor

2018
Influence of Treatment With Tumor-Treating Fields on Health-Related Quality of Life of Patients With Newly Diagnosed Glioblastoma: A Secondary Analysis of a Randomized Clinical Trial.
    JAMA oncology, 2018, Apr-01, Volume: 4, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Brain Neoplasms; Chemoradiotherapy; Combined Modality Therapy; Cytor

2018
Influence of Treatment With Tumor-Treating Fields on Health-Related Quality of Life of Patients With Newly Diagnosed Glioblastoma: A Secondary Analysis of a Randomized Clinical Trial.
    JAMA oncology, 2018, Apr-01, Volume: 4, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Brain Neoplasms; Chemoradiotherapy; Combined Modality Therapy; Cytor

2018
Influence of Treatment With Tumor-Treating Fields on Health-Related Quality of Life of Patients With Newly Diagnosed Glioblastoma: A Secondary Analysis of a Randomized Clinical Trial.
    JAMA oncology, 2018, Apr-01, Volume: 4, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Brain Neoplasms; Chemoradiotherapy; Combined Modality Therapy; Cytor

2018
Influence of Treatment With Tumor-Treating Fields on Health-Related Quality of Life of Patients With Newly Diagnosed Glioblastoma: A Secondary Analysis of a Randomized Clinical Trial.
    JAMA oncology, 2018, Apr-01, Volume: 4, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Brain Neoplasms; Chemoradiotherapy; Combined Modality Therapy; Cytor

2018
Influence of Treatment With Tumor-Treating Fields on Health-Related Quality of Life of Patients With Newly Diagnosed Glioblastoma: A Secondary Analysis of a Randomized Clinical Trial.
    JAMA oncology, 2018, Apr-01, Volume: 4, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Brain Neoplasms; Chemoradiotherapy; Combined Modality Therapy; Cytor

2018
Influence of Treatment With Tumor-Treating Fields on Health-Related Quality of Life of Patients With Newly Diagnosed Glioblastoma: A Secondary Analysis of a Randomized Clinical Trial.
    JAMA oncology, 2018, Apr-01, Volume: 4, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Brain Neoplasms; Chemoradiotherapy; Combined Modality Therapy; Cytor

2018
Influence of Treatment With Tumor-Treating Fields on Health-Related Quality of Life of Patients With Newly Diagnosed Glioblastoma: A Secondary Analysis of a Randomized Clinical Trial.
    JAMA oncology, 2018, Apr-01, Volume: 4, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Brain Neoplasms; Chemoradiotherapy; Combined Modality Therapy; Cytor

2018
Influence of Treatment With Tumor-Treating Fields on Health-Related Quality of Life of Patients With Newly Diagnosed Glioblastoma: A Secondary Analysis of a Randomized Clinical Trial.
    JAMA oncology, 2018, Apr-01, Volume: 4, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Brain Neoplasms; Chemoradiotherapy; Combined Modality Therapy; Cytor

2018
Influence of Treatment With Tumor-Treating Fields on Health-Related Quality of Life of Patients With Newly Diagnosed Glioblastoma: A Secondary Analysis of a Randomized Clinical Trial.
    JAMA oncology, 2018, Apr-01, Volume: 4, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Brain Neoplasms; Chemoradiotherapy; Combined Modality Therapy; Cytor

2018
Influence of Treatment With Tumor-Treating Fields on Health-Related Quality of Life of Patients With Newly Diagnosed Glioblastoma: A Secondary Analysis of a Randomized Clinical Trial.
    JAMA oncology, 2018, Apr-01, Volume: 4, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Brain Neoplasms; Chemoradiotherapy; Combined Modality Therapy; Cytor

2018
Influence of Treatment With Tumor-Treating Fields on Health-Related Quality of Life of Patients With Newly Diagnosed Glioblastoma: A Secondary Analysis of a Randomized Clinical Trial.
    JAMA oncology, 2018, Apr-01, Volume: 4, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Brain Neoplasms; Chemoradiotherapy; Combined Modality Therapy; Cytor

2018
Influence of Treatment With Tumor-Treating Fields on Health-Related Quality of Life of Patients With Newly Diagnosed Glioblastoma: A Secondary Analysis of a Randomized Clinical Trial.
    JAMA oncology, 2018, Apr-01, Volume: 4, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Brain Neoplasms; Chemoradiotherapy; Combined Modality Therapy; Cytor

2018
Influence of Treatment With Tumor-Treating Fields on Health-Related Quality of Life of Patients With Newly Diagnosed Glioblastoma: A Secondary Analysis of a Randomized Clinical Trial.
    JAMA oncology, 2018, Apr-01, Volume: 4, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Brain Neoplasms; Chemoradiotherapy; Combined Modality Therapy; Cytor

2018
Influence of Treatment With Tumor-Treating Fields on Health-Related Quality of Life of Patients With Newly Diagnosed Glioblastoma: A Secondary Analysis of a Randomized Clinical Trial.
    JAMA oncology, 2018, Apr-01, Volume: 4, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Brain Neoplasms; Chemoradiotherapy; Combined Modality Therapy; Cytor

2018
Influence of Treatment With Tumor-Treating Fields on Health-Related Quality of Life of Patients With Newly Diagnosed Glioblastoma: A Secondary Analysis of a Randomized Clinical Trial.
    JAMA oncology, 2018, Apr-01, Volume: 4, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Brain Neoplasms; Chemoradiotherapy; Combined Modality Therapy; Cytor

2018
Influence of Treatment With Tumor-Treating Fields on Health-Related Quality of Life of Patients With Newly Diagnosed Glioblastoma: A Secondary Analysis of a Randomized Clinical Trial.
    JAMA oncology, 2018, Apr-01, Volume: 4, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Brain Neoplasms; Chemoradiotherapy; Combined Modality Therapy; Cytor

2018
Influence of Treatment With Tumor-Treating Fields on Health-Related Quality of Life of Patients With Newly Diagnosed Glioblastoma: A Secondary Analysis of a Randomized Clinical Trial.
    JAMA oncology, 2018, Apr-01, Volume: 4, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Brain Neoplasms; Chemoradiotherapy; Combined Modality Therapy; Cytor

2018
Influence of Treatment With Tumor-Treating Fields on Health-Related Quality of Life of Patients With Newly Diagnosed Glioblastoma: A Secondary Analysis of a Randomized Clinical Trial.
    JAMA oncology, 2018, Apr-01, Volume: 4, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Brain Neoplasms; Chemoradiotherapy; Combined Modality Therapy; Cytor

2018
Influence of Treatment With Tumor-Treating Fields on Health-Related Quality of Life of Patients With Newly Diagnosed Glioblastoma: A Secondary Analysis of a Randomized Clinical Trial.
    JAMA oncology, 2018, Apr-01, Volume: 4, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Brain Neoplasms; Chemoradiotherapy; Combined Modality Therapy; Cytor

2018
Influence of Treatment With Tumor-Treating Fields on Health-Related Quality of Life of Patients With Newly Diagnosed Glioblastoma: A Secondary Analysis of a Randomized Clinical Trial.
    JAMA oncology, 2018, Apr-01, Volume: 4, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Brain Neoplasms; Chemoradiotherapy; Combined Modality Therapy; Cytor

2018
Influence of Treatment With Tumor-Treating Fields on Health-Related Quality of Life of Patients With Newly Diagnosed Glioblastoma: A Secondary Analysis of a Randomized Clinical Trial.
    JAMA oncology, 2018, Apr-01, Volume: 4, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Brain Neoplasms; Chemoradiotherapy; Combined Modality Therapy; Cytor

2018
Influence of Treatment With Tumor-Treating Fields on Health-Related Quality of Life of Patients With Newly Diagnosed Glioblastoma: A Secondary Analysis of a Randomized Clinical Trial.
    JAMA oncology, 2018, Apr-01, Volume: 4, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Brain Neoplasms; Chemoradiotherapy; Combined Modality Therapy; Cytor

2018
Influence of Treatment With Tumor-Treating Fields on Health-Related Quality of Life of Patients With Newly Diagnosed Glioblastoma: A Secondary Analysis of a Randomized Clinical Trial.
    JAMA oncology, 2018, Apr-01, Volume: 4, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Brain Neoplasms; Chemoradiotherapy; Combined Modality Therapy; Cytor

2018
Influence of Treatment With Tumor-Treating Fields on Health-Related Quality of Life of Patients With Newly Diagnosed Glioblastoma: A Secondary Analysis of a Randomized Clinical Trial.
    JAMA oncology, 2018, Apr-01, Volume: 4, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Brain Neoplasms; Chemoradiotherapy; Combined Modality Therapy; Cytor

2018
Influence of Treatment With Tumor-Treating Fields on Health-Related Quality of Life of Patients With Newly Diagnosed Glioblastoma: A Secondary Analysis of a Randomized Clinical Trial.
    JAMA oncology, 2018, Apr-01, Volume: 4, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Brain Neoplasms; Chemoradiotherapy; Combined Modality Therapy; Cytor

2018
Influence of Treatment With Tumor-Treating Fields on Health-Related Quality of Life of Patients With Newly Diagnosed Glioblastoma: A Secondary Analysis of a Randomized Clinical Trial.
    JAMA oncology, 2018, Apr-01, Volume: 4, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Brain Neoplasms; Chemoradiotherapy; Combined Modality Therapy; Cytor

2018
Influence of Treatment With Tumor-Treating Fields on Health-Related Quality of Life of Patients With Newly Diagnosed Glioblastoma: A Secondary Analysis of a Randomized Clinical Trial.
    JAMA oncology, 2018, Apr-01, Volume: 4, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Brain Neoplasms; Chemoradiotherapy; Combined Modality Therapy; Cytor

2018
Influence of Treatment With Tumor-Treating Fields on Health-Related Quality of Life of Patients With Newly Diagnosed Glioblastoma: A Secondary Analysis of a Randomized Clinical Trial.
    JAMA oncology, 2018, Apr-01, Volume: 4, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Brain Neoplasms; Chemoradiotherapy; Combined Modality Therapy; Cytor

2018
Influence of Treatment With Tumor-Treating Fields on Health-Related Quality of Life of Patients With Newly Diagnosed Glioblastoma: A Secondary Analysis of a Randomized Clinical Trial.
    JAMA oncology, 2018, Apr-01, Volume: 4, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Brain Neoplasms; Chemoradiotherapy; Combined Modality Therapy; Cytor

2018
Influence of Treatment With Tumor-Treating Fields on Health-Related Quality of Life of Patients With Newly Diagnosed Glioblastoma: A Secondary Analysis of a Randomized Clinical Trial.
    JAMA oncology, 2018, Apr-01, Volume: 4, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Brain Neoplasms; Chemoradiotherapy; Combined Modality Therapy; Cytor

2018
Influence of Treatment With Tumor-Treating Fields on Health-Related Quality of Life of Patients With Newly Diagnosed Glioblastoma: A Secondary Analysis of a Randomized Clinical Trial.
    JAMA oncology, 2018, Apr-01, Volume: 4, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Brain Neoplasms; Chemoradiotherapy; Combined Modality Therapy; Cytor

2018
Influence of Treatment With Tumor-Treating Fields on Health-Related Quality of Life of Patients With Newly Diagnosed Glioblastoma: A Secondary Analysis of a Randomized Clinical Trial.
    JAMA oncology, 2018, Apr-01, Volume: 4, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Brain Neoplasms; Chemoradiotherapy; Combined Modality Therapy; Cytor

2018
Influence of Treatment With Tumor-Treating Fields on Health-Related Quality of Life of Patients With Newly Diagnosed Glioblastoma: A Secondary Analysis of a Randomized Clinical Trial.
    JAMA oncology, 2018, Apr-01, Volume: 4, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Brain Neoplasms; Chemoradiotherapy; Combined Modality Therapy; Cytor

2018
Influence of Treatment With Tumor-Treating Fields on Health-Related Quality of Life of Patients With Newly Diagnosed Glioblastoma: A Secondary Analysis of a Randomized Clinical Trial.
    JAMA oncology, 2018, Apr-01, Volume: 4, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Brain Neoplasms; Chemoradiotherapy; Combined Modality Therapy; Cytor

2018
Influence of Treatment With Tumor-Treating Fields on Health-Related Quality of Life of Patients With Newly Diagnosed Glioblastoma: A Secondary Analysis of a Randomized Clinical Trial.
    JAMA oncology, 2018, Apr-01, Volume: 4, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Brain Neoplasms; Chemoradiotherapy; Combined Modality Therapy; Cytor

2018
Influence of Treatment With Tumor-Treating Fields on Health-Related Quality of Life of Patients With Newly Diagnosed Glioblastoma: A Secondary Analysis of a Randomized Clinical Trial.
    JAMA oncology, 2018, Apr-01, Volume: 4, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Brain Neoplasms; Chemoradiotherapy; Combined Modality Therapy; Cytor

2018
Influence of Treatment With Tumor-Treating Fields on Health-Related Quality of Life of Patients With Newly Diagnosed Glioblastoma: A Secondary Analysis of a Randomized Clinical Trial.
    JAMA oncology, 2018, Apr-01, Volume: 4, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Brain Neoplasms; Chemoradiotherapy; Combined Modality Therapy; Cytor

2018
Short delay in initiation of radiotherapy for patients with glioblastoma-effect of concurrent chemotherapy: a secondary analysis from the NRG Oncology/Radiation Therapy Oncology Group database.
    Neuro-oncology, 2018, 06-18, Volume: 20, Issue:7

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Brain N

2018
Short delay in initiation of radiotherapy for patients with glioblastoma-effect of concurrent chemotherapy: a secondary analysis from the NRG Oncology/Radiation Therapy Oncology Group database.
    Neuro-oncology, 2018, 06-18, Volume: 20, Issue:7

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Brain N

2018
Short delay in initiation of radiotherapy for patients with glioblastoma-effect of concurrent chemotherapy: a secondary analysis from the NRG Oncology/Radiation Therapy Oncology Group database.
    Neuro-oncology, 2018, 06-18, Volume: 20, Issue:7

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Brain N

2018
Cost-effectiveness of the long-term use of temozolomide for treating newly diagnosed glioblastoma in Germany.
    Journal of neuro-oncology, 2018, Volume: 138, Issue:2

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Cost-Benefit Ana

2018
Cost-effectiveness of the long-term use of temozolomide for treating newly diagnosed glioblastoma in Germany.
    Journal of neuro-oncology, 2018, Volume: 138, Issue:2

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Cost-Benefit Ana

2018
Cost-effectiveness of the long-term use of temozolomide for treating newly diagnosed glioblastoma in Germany.
    Journal of neuro-oncology, 2018, Volume: 138, Issue:2

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Cost-Benefit Ana

2018
Expression-based intrinsic glioma subtypes are prognostic in low-grade gliomas of the EORTC22033-26033 clinical trial.
    European journal of cancer (Oxford, England : 1990), 2018, Volume: 94

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Biomarkers, Tumor; Brain Neoplasms; Female; Glioma;

2018
Expression-based intrinsic glioma subtypes are prognostic in low-grade gliomas of the EORTC22033-26033 clinical trial.
    European journal of cancer (Oxford, England : 1990), 2018, Volume: 94

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Biomarkers, Tumor; Brain Neoplasms; Female; Glioma;

2018
Expression-based intrinsic glioma subtypes are prognostic in low-grade gliomas of the EORTC22033-26033 clinical trial.
    European journal of cancer (Oxford, England : 1990), 2018, Volume: 94

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Biomarkers, Tumor; Brain Neoplasms; Female; Glioma;

2018
Prognostic value of contrast enhancement and FLAIR for survival in newly diagnosed glioblastoma treated with and without bevacizumab: results from ACRIN 6686.
    Neuro-oncology, 2018, 09-03, Volume: 20, Issue:10

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Brain N

2018
Prognostic value of contrast enhancement and FLAIR for survival in newly diagnosed glioblastoma treated with and without bevacizumab: results from ACRIN 6686.
    Neuro-oncology, 2018, 09-03, Volume: 20, Issue:10

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Brain N

2018
Prognostic value of contrast enhancement and FLAIR for survival in newly diagnosed glioblastoma treated with and without bevacizumab: results from ACRIN 6686.
    Neuro-oncology, 2018, 09-03, Volume: 20, Issue:10

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Brain N

2018
Radiotherapy quality assurance for the RTOG 0834/EORTC 26053-22054/NCIC CTG CEC.1/CATNON intergroup trial "concurrent and adjuvant temozolomide chemotherapy in newly diagnosed non-1p/19q deleted anaplastic glioma": Individual case review analysis.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2018, Volume: 127, Issue:2

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant; Chromosome Deletion; Chr

2018
Radiotherapy quality assurance for the RTOG 0834/EORTC 26053-22054/NCIC CTG CEC.1/CATNON intergroup trial "concurrent and adjuvant temozolomide chemotherapy in newly diagnosed non-1p/19q deleted anaplastic glioma": Individual case review analysis.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2018, Volume: 127, Issue:2

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant; Chromosome Deletion; Chr

2018
Radiotherapy quality assurance for the RTOG 0834/EORTC 26053-22054/NCIC CTG CEC.1/CATNON intergroup trial "concurrent and adjuvant temozolomide chemotherapy in newly diagnosed non-1p/19q deleted anaplastic glioma": Individual case review analysis.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2018, Volume: 127, Issue:2

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant; Chromosome Deletion; Chr

2018
Interim Results of a Phase II Study of Hypofractionated Radiotherapy with Concurrent Temozolomide Followed by Adjuvant Temozolomide in Patients over 70 Years Old with Newly Diagnosed Glioblastoma.
    Oncology, 2018, Volume: 95, Issue:1

    Topics: Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Disease Pr

2018
Interim Results of a Phase II Study of Hypofractionated Radiotherapy with Concurrent Temozolomide Followed by Adjuvant Temozolomide in Patients over 70 Years Old with Newly Diagnosed Glioblastoma.
    Oncology, 2018, Volume: 95, Issue:1

    Topics: Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Disease Pr

2018
Interim Results of a Phase II Study of Hypofractionated Radiotherapy with Concurrent Temozolomide Followed by Adjuvant Temozolomide in Patients over 70 Years Old with Newly Diagnosed Glioblastoma.
    Oncology, 2018, Volume: 95, Issue:1

    Topics: Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Disease Pr

2018
Shadow study: randomized comparison of clinic with video follow-up in glioma undergoing adjuvant temozolomide therapy.
    CNS oncology, 2018, Volume: 7, Issue:2

    Topics: Adult; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant; Female; Follow-Up

2018
Shadow study: randomized comparison of clinic with video follow-up in glioma undergoing adjuvant temozolomide therapy.
    CNS oncology, 2018, Volume: 7, Issue:2

    Topics: Adult; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant; Female; Follow-Up

2018
Shadow study: randomized comparison of clinic with video follow-up in glioma undergoing adjuvant temozolomide therapy.
    CNS oncology, 2018, Volume: 7, Issue:2

    Topics: Adult; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant; Female; Follow-Up

2018
Post-chemoradiation volumetric response predicts survival in newly diagnosed glioblastoma treated with radiation, temozolomide, and bevacizumab or placebo.
    Neuro-oncology, 2018, 10-09, Volume: 20, Issue:11

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bevacizu

2018
Post-chemoradiation volumetric response predicts survival in newly diagnosed glioblastoma treated with radiation, temozolomide, and bevacizumab or placebo.
    Neuro-oncology, 2018, 10-09, Volume: 20, Issue:11

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bevacizu

2018
Post-chemoradiation volumetric response predicts survival in newly diagnosed glioblastoma treated with radiation, temozolomide, and bevacizumab or placebo.
    Neuro-oncology, 2018, 10-09, Volume: 20, Issue:11

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bevacizu

2018
Hypofractionated accelerated radiotherapy (HART) with concurrent and adjuvant temozolomide in newly diagnosed glioblastoma: a phase II randomized trial (HART-GBM trial).
    Journal of neuro-oncology, 2018, Volume: 140, Issue:1

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Child; Female; Follow-U

2018
Hypofractionated accelerated radiotherapy (HART) with concurrent and adjuvant temozolomide in newly diagnosed glioblastoma: a phase II randomized trial (HART-GBM trial).
    Journal of neuro-oncology, 2018, Volume: 140, Issue:1

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Child; Female; Follow-U

2018
Hypofractionated accelerated radiotherapy (HART) with concurrent and adjuvant temozolomide in newly diagnosed glioblastoma: a phase II randomized trial (HART-GBM trial).
    Journal of neuro-oncology, 2018, Volume: 140, Issue:1

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Child; Female; Follow-U

2018
Association of MGMT Promoter Methylation Status With Survival Outcomes in Patients With High-Risk Glioma Treated With Radiotherapy and Temozolomide: An Analysis From the NRG Oncology/RTOG 0424 Trial.
    JAMA oncology, 2018, 10-01, Volume: 4, Issue:10

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; DNA Methylation;

2018
Association of MGMT Promoter Methylation Status With Survival Outcomes in Patients With High-Risk Glioma Treated With Radiotherapy and Temozolomide: An Analysis From the NRG Oncology/RTOG 0424 Trial.
    JAMA oncology, 2018, 10-01, Volume: 4, Issue:10

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; DNA Methylation;

2018
Association of MGMT Promoter Methylation Status With Survival Outcomes in Patients With High-Risk Glioma Treated With Radiotherapy and Temozolomide: An Analysis From the NRG Oncology/RTOG 0424 Trial.
    JAMA oncology, 2018, 10-01, Volume: 4, Issue:10

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; DNA Methylation;

2018
High-dose fotemustine in temozolomide-pretreated glioblastoma multiforme patients: A phase I/II trial.
    Medicine, 2018, Volume: 97, Issue:27

    Topics: Administration, Intravenous; Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Brain Neoplasms;

2018
High-dose fotemustine in temozolomide-pretreated glioblastoma multiforme patients: A phase I/II trial.
    Medicine, 2018, Volume: 97, Issue:27

    Topics: Administration, Intravenous; Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Brain Neoplasms;

2018
High-dose fotemustine in temozolomide-pretreated glioblastoma multiforme patients: A phase I/II trial.
    Medicine, 2018, Volume: 97, Issue:27

    Topics: Administration, Intravenous; Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Brain Neoplasms;

2018
Safety and efficacy of depatuxizumab mafodotin + temozolomide in patients with EGFR-amplified, recurrent glioblastoma: results from an international phase I multicenter trial.
    Neuro-oncology, 2019, 01-01, Volume: 21, Issue:1

    Topics: Adult; Aged; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Brai

2019
Safety and efficacy of depatuxizumab mafodotin + temozolomide in patients with EGFR-amplified, recurrent glioblastoma: results from an international phase I multicenter trial.
    Neuro-oncology, 2019, 01-01, Volume: 21, Issue:1

    Topics: Adult; Aged; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Brai

2019
Safety and efficacy of depatuxizumab mafodotin + temozolomide in patients with EGFR-amplified, recurrent glioblastoma: results from an international phase I multicenter trial.
    Neuro-oncology, 2019, 01-01, Volume: 21, Issue:1

    Topics: Adult; Aged; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Brai

2019
Safety and efficacy of depatuxizumab mafodotin + temozolomide in patients with EGFR-amplified, recurrent glioblastoma: results from an international phase I multicenter trial.
    Neuro-oncology, 2019, 01-01, Volume: 21, Issue:1

    Topics: Adult; Aged; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Brai

2019
Safety and efficacy of depatuxizumab mafodotin + temozolomide in patients with EGFR-amplified, recurrent glioblastoma: results from an international phase I multicenter trial.
    Neuro-oncology, 2019, 01-01, Volume: 21, Issue:1

    Topics: Adult; Aged; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Brai

2019
Safety and efficacy of depatuxizumab mafodotin + temozolomide in patients with EGFR-amplified, recurrent glioblastoma: results from an international phase I multicenter trial.
    Neuro-oncology, 2019, 01-01, Volume: 21, Issue:1

    Topics: Adult; Aged; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Brai

2019
Safety and efficacy of depatuxizumab mafodotin + temozolomide in patients with EGFR-amplified, recurrent glioblastoma: results from an international phase I multicenter trial.
    Neuro-oncology, 2019, 01-01, Volume: 21, Issue:1

    Topics: Adult; Aged; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Brai

2019
Safety and efficacy of depatuxizumab mafodotin + temozolomide in patients with EGFR-amplified, recurrent glioblastoma: results from an international phase I multicenter trial.
    Neuro-oncology, 2019, 01-01, Volume: 21, Issue:1

    Topics: Adult; Aged; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Brai

2019
Safety and efficacy of depatuxizumab mafodotin + temozolomide in patients with EGFR-amplified, recurrent glioblastoma: results from an international phase I multicenter trial.
    Neuro-oncology, 2019, 01-01, Volume: 21, Issue:1

    Topics: Adult; Aged; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Brai

2019
Safety and efficacy of depatuxizumab mafodotin + temozolomide in patients with EGFR-amplified, recurrent glioblastoma: results from an international phase I multicenter trial.
    Neuro-oncology, 2019, 01-01, Volume: 21, Issue:1

    Topics: Adult; Aged; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Brai

2019
Safety and efficacy of depatuxizumab mafodotin + temozolomide in patients with EGFR-amplified, recurrent glioblastoma: results from an international phase I multicenter trial.
    Neuro-oncology, 2019, 01-01, Volume: 21, Issue:1

    Topics: Adult; Aged; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Brai

2019
Safety and efficacy of depatuxizumab mafodotin + temozolomide in patients with EGFR-amplified, recurrent glioblastoma: results from an international phase I multicenter trial.
    Neuro-oncology, 2019, 01-01, Volume: 21, Issue:1

    Topics: Adult; Aged; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Brai

2019
Safety and efficacy of depatuxizumab mafodotin + temozolomide in patients with EGFR-amplified, recurrent glioblastoma: results from an international phase I multicenter trial.
    Neuro-oncology, 2019, 01-01, Volume: 21, Issue:1

    Topics: Adult; Aged; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Brai

2019
Safety and efficacy of depatuxizumab mafodotin + temozolomide in patients with EGFR-amplified, recurrent glioblastoma: results from an international phase I multicenter trial.
    Neuro-oncology, 2019, 01-01, Volume: 21, Issue:1

    Topics: Adult; Aged; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Brai

2019
Safety and efficacy of depatuxizumab mafodotin + temozolomide in patients with EGFR-amplified, recurrent glioblastoma: results from an international phase I multicenter trial.
    Neuro-oncology, 2019, 01-01, Volume: 21, Issue:1

    Topics: Adult; Aged; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Brai

2019
Safety and efficacy of depatuxizumab mafodotin + temozolomide in patients with EGFR-amplified, recurrent glioblastoma: results from an international phase I multicenter trial.
    Neuro-oncology, 2019, 01-01, Volume: 21, Issue:1

    Topics: Adult; Aged; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Brai

2019
Safety and efficacy of depatuxizumab mafodotin + temozolomide in patients with EGFR-amplified, recurrent glioblastoma: results from an international phase I multicenter trial.
    Neuro-oncology, 2019, 01-01, Volume: 21, Issue:1

    Topics: Adult; Aged; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Brai

2019
Safety and efficacy of depatuxizumab mafodotin + temozolomide in patients with EGFR-amplified, recurrent glioblastoma: results from an international phase I multicenter trial.
    Neuro-oncology, 2019, 01-01, Volume: 21, Issue:1

    Topics: Adult; Aged; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Brai

2019
Safety and efficacy of depatuxizumab mafodotin + temozolomide in patients with EGFR-amplified, recurrent glioblastoma: results from an international phase I multicenter trial.
    Neuro-oncology, 2019, 01-01, Volume: 21, Issue:1

    Topics: Adult; Aged; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Brai

2019
Safety and efficacy of depatuxizumab mafodotin + temozolomide in patients with EGFR-amplified, recurrent glioblastoma: results from an international phase I multicenter trial.
    Neuro-oncology, 2019, 01-01, Volume: 21, Issue:1

    Topics: Adult; Aged; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Brai

2019
Safety and efficacy of depatuxizumab mafodotin + temozolomide in patients with EGFR-amplified, recurrent glioblastoma: results from an international phase I multicenter trial.
    Neuro-oncology, 2019, 01-01, Volume: 21, Issue:1

    Topics: Adult; Aged; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Brai

2019
Safety and efficacy of depatuxizumab mafodotin + temozolomide in patients with EGFR-amplified, recurrent glioblastoma: results from an international phase I multicenter trial.
    Neuro-oncology, 2019, 01-01, Volume: 21, Issue:1

    Topics: Adult; Aged; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Brai

2019
Safety and efficacy of depatuxizumab mafodotin + temozolomide in patients with EGFR-amplified, recurrent glioblastoma: results from an international phase I multicenter trial.
    Neuro-oncology, 2019, 01-01, Volume: 21, Issue:1

    Topics: Adult; Aged; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Brai

2019
Safety and efficacy of depatuxizumab mafodotin + temozolomide in patients with EGFR-amplified, recurrent glioblastoma: results from an international phase I multicenter trial.
    Neuro-oncology, 2019, 01-01, Volume: 21, Issue:1

    Topics: Adult; Aged; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Brai

2019
Safety and efficacy of depatuxizumab mafodotin + temozolomide in patients with EGFR-amplified, recurrent glioblastoma: results from an international phase I multicenter trial.
    Neuro-oncology, 2019, 01-01, Volume: 21, Issue:1

    Topics: Adult; Aged; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Brai

2019
Safety and efficacy of depatuxizumab mafodotin + temozolomide in patients with EGFR-amplified, recurrent glioblastoma: results from an international phase I multicenter trial.
    Neuro-oncology, 2019, 01-01, Volume: 21, Issue:1

    Topics: Adult; Aged; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Brai

2019
Safety and efficacy of depatuxizumab mafodotin + temozolomide in patients with EGFR-amplified, recurrent glioblastoma: results from an international phase I multicenter trial.
    Neuro-oncology, 2019, 01-01, Volume: 21, Issue:1

    Topics: Adult; Aged; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Brai

2019
Bevacizumab and temozolomide in patients with first recurrence of WHO grade II and III glioma, without 1p/19q co-deletion (TAVAREC): a randomised controlled phase 2 EORTC trial.
    The Lancet. Oncology, 2018, Volume: 19, Issue:9

    Topics: Adult; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Immunological; Antineoplastic Combi

2018
Bevacizumab and temozolomide in patients with first recurrence of WHO grade II and III glioma, without 1p/19q co-deletion (TAVAREC): a randomised controlled phase 2 EORTC trial.
    The Lancet. Oncology, 2018, Volume: 19, Issue:9

    Topics: Adult; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Immunological; Antineoplastic Combi

2018
Bevacizumab and temozolomide in patients with first recurrence of WHO grade II and III glioma, without 1p/19q co-deletion (TAVAREC): a randomised controlled phase 2 EORTC trial.
    The Lancet. Oncology, 2018, Volume: 19, Issue:9

    Topics: Adult; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Immunological; Antineoplastic Combi

2018
Phase II study of hypofractionated radiation therapy in elderly patients with newly diagnosed glioblastoma with poor prognosis.
    Tumori, 2019, Volume: 105, Issue:1

    Topics: Aged; Aged, 80 and over; Brain Neoplasms; Chemoradiotherapy; Chemotherapy, Adjuvant; Disease-Free Su

2019
Phase II study of hypofractionated radiation therapy in elderly patients with newly diagnosed glioblastoma with poor prognosis.
    Tumori, 2019, Volume: 105, Issue:1

    Topics: Aged; Aged, 80 and over; Brain Neoplasms; Chemoradiotherapy; Chemotherapy, Adjuvant; Disease-Free Su

2019
Phase II study of hypofractionated radiation therapy in elderly patients with newly diagnosed glioblastoma with poor prognosis.
    Tumori, 2019, Volume: 105, Issue:1

    Topics: Aged; Aged, 80 and over; Brain Neoplasms; Chemoradiotherapy; Chemotherapy, Adjuvant; Disease-Free Su

2019
Phase II Study of Iniparib with Concurrent Chemoradiation in Patients with Newly Diagnosed Glioblastoma.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2019, 01-01, Volume: 25, Issue:1

    Topics: Benzamides; Brain Neoplasms; Chemoradiotherapy; Combined Modality Therapy; Female; Glioblastoma; Hum

2019
Phase II Study of Iniparib with Concurrent Chemoradiation in Patients with Newly Diagnosed Glioblastoma.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2019, 01-01, Volume: 25, Issue:1

    Topics: Benzamides; Brain Neoplasms; Chemoradiotherapy; Combined Modality Therapy; Female; Glioblastoma; Hum

2019
Phase II Study of Iniparib with Concurrent Chemoradiation in Patients with Newly Diagnosed Glioblastoma.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2019, 01-01, Volume: 25, Issue:1

    Topics: Benzamides; Brain Neoplasms; Chemoradiotherapy; Combined Modality Therapy; Female; Glioblastoma; Hum

2019
N2M2 (NOA-20) phase I/II trial of molecularly matched targeted therapies plus radiotherapy in patients with newly diagnosed non-MGMT hypermethylated glioblastoma.
    Neuro-oncology, 2019, 01-01, Volume: 21, Issue:1

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Biomarkers, Tumor; Br

2019
N2M2 (NOA-20) phase I/II trial of molecularly matched targeted therapies plus radiotherapy in patients with newly diagnosed non-MGMT hypermethylated glioblastoma.
    Neuro-oncology, 2019, 01-01, Volume: 21, Issue:1

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Biomarkers, Tumor; Br

2019
N2M2 (NOA-20) phase I/II trial of molecularly matched targeted therapies plus radiotherapy in patients with newly diagnosed non-MGMT hypermethylated glioblastoma.
    Neuro-oncology, 2019, 01-01, Volume: 21, Issue:1

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Biomarkers, Tumor; Br

2019
Phase 1 lead-in to a phase 2 factorial study of temozolomide plus memantine, mefloquine, and metformin as postradiation adjuvant therapy for newly diagnosed glioblastoma.
    Cancer, 2019, 02-01, Volume: 125, Issue:3

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Chemotherapy, Adjuvant

2019
Phase 1 lead-in to a phase 2 factorial study of temozolomide plus memantine, mefloquine, and metformin as postradiation adjuvant therapy for newly diagnosed glioblastoma.
    Cancer, 2019, 02-01, Volume: 125, Issue:3

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Chemotherapy, Adjuvant

2019
Phase 1 lead-in to a phase 2 factorial study of temozolomide plus memantine, mefloquine, and metformin as postradiation adjuvant therapy for newly diagnosed glioblastoma.
    Cancer, 2019, 02-01, Volume: 125, Issue:3

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Chemotherapy, Adjuvant

2019
Intratumoral temozolomide in spontaneous canine gliomas: feasibility of a novel therapy using implanted microcylinders.
    Veterinary medicine and science, 2019, Volume: 5, Issue:1

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dog Diseases; Dogs; Drug Implants; Fema

2019
Intratumoral temozolomide in spontaneous canine gliomas: feasibility of a novel therapy using implanted microcylinders.
    Veterinary medicine and science, 2019, Volume: 5, Issue:1

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dog Diseases; Dogs; Drug Implants; Fema

2019
Intratumoral temozolomide in spontaneous canine gliomas: feasibility of a novel therapy using implanted microcylinders.
    Veterinary medicine and science, 2019, Volume: 5, Issue:1

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dog Diseases; Dogs; Drug Implants; Fema

2019
A multicenter phase II study of temozolomide plus disulfiram and copper for recurrent temozolomide-resistant glioblastoma.
    Journal of neuro-oncology, 2019, Volume: 142, Issue:3

    Topics: Acetaldehyde Dehydrogenase Inhibitors; Adult; Aged; Antineoplastic Agents, Alkylating; Antineoplasti

2019
A multicenter phase II study of temozolomide plus disulfiram and copper for recurrent temozolomide-resistant glioblastoma.
    Journal of neuro-oncology, 2019, Volume: 142, Issue:3

    Topics: Acetaldehyde Dehydrogenase Inhibitors; Adult; Aged; Antineoplastic Agents, Alkylating; Antineoplasti

2019
A multicenter phase II study of temozolomide plus disulfiram and copper for recurrent temozolomide-resistant glioblastoma.
    Journal of neuro-oncology, 2019, Volume: 142, Issue:3

    Topics: Acetaldehyde Dehydrogenase Inhibitors; Adult; Aged; Antineoplastic Agents, Alkylating; Antineoplasti

2019
Carbon ion radiotherapy boost in the treatment of glioblastoma: a randomized phase I/III clinical trial.
    Cancer communications (London, England), 2019, 02-20, Volume: 39, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Clinical Trials, Phase I as Topic; Clinical Tria

2019
Carbon ion radiotherapy boost in the treatment of glioblastoma: a randomized phase I/III clinical trial.
    Cancer communications (London, England), 2019, 02-20, Volume: 39, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Clinical Trials, Phase I as Topic; Clinical Tria

2019
Carbon ion radiotherapy boost in the treatment of glioblastoma: a randomized phase I/III clinical trial.
    Cancer communications (London, England), 2019, 02-20, Volume: 39, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Clinical Trials, Phase I as Topic; Clinical Tria

2019
Dose-painting multicenter phase III trial in newly diagnosed glioblastoma: the SPECTRO-GLIO trial comparing arm A standard radiochemotherapy to arm B radiochemotherapy with simultaneous integrated boost guided by MR spectroscopic imaging.
    BMC cancer, 2019, Feb-21, Volume: 19, Issue:1

    Topics: Adult; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Diagnostic Imaging; Gl

2019
Dose-painting multicenter phase III trial in newly diagnosed glioblastoma: the SPECTRO-GLIO trial comparing arm A standard radiochemotherapy to arm B radiochemotherapy with simultaneous integrated boost guided by MR spectroscopic imaging.
    BMC cancer, 2019, Feb-21, Volume: 19, Issue:1

    Topics: Adult; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Diagnostic Imaging; Gl

2019
Dose-painting multicenter phase III trial in newly diagnosed glioblastoma: the SPECTRO-GLIO trial comparing arm A standard radiochemotherapy to arm B radiochemotherapy with simultaneous integrated boost guided by MR spectroscopic imaging.
    BMC cancer, 2019, Feb-21, Volume: 19, Issue:1

    Topics: Adult; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Diagnostic Imaging; Gl

2019
Dose-painting multicenter phase III trial in newly diagnosed glioblastoma: the SPECTRO-GLIO trial comparing arm A standard radiochemotherapy to arm B radiochemotherapy with simultaneous integrated boost guided by MR spectroscopic imaging.
    BMC cancer, 2019, Feb-21, Volume: 19, Issue:1

    Topics: Adult; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Diagnostic Imaging; Gl

2019
Dose-painting multicenter phase III trial in newly diagnosed glioblastoma: the SPECTRO-GLIO trial comparing arm A standard radiochemotherapy to arm B radiochemotherapy with simultaneous integrated boost guided by MR spectroscopic imaging.
    BMC cancer, 2019, Feb-21, Volume: 19, Issue:1

    Topics: Adult; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Diagnostic Imaging; Gl

2019
Dose-painting multicenter phase III trial in newly diagnosed glioblastoma: the SPECTRO-GLIO trial comparing arm A standard radiochemotherapy to arm B radiochemotherapy with simultaneous integrated boost guided by MR spectroscopic imaging.
    BMC cancer, 2019, Feb-21, Volume: 19, Issue:1

    Topics: Adult; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Diagnostic Imaging; Gl

2019
Dose-painting multicenter phase III trial in newly diagnosed glioblastoma: the SPECTRO-GLIO trial comparing arm A standard radiochemotherapy to arm B radiochemotherapy with simultaneous integrated boost guided by MR spectroscopic imaging.
    BMC cancer, 2019, Feb-21, Volume: 19, Issue:1

    Topics: Adult; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Diagnostic Imaging; Gl

2019
Dose-painting multicenter phase III trial in newly diagnosed glioblastoma: the SPECTRO-GLIO trial comparing arm A standard radiochemotherapy to arm B radiochemotherapy with simultaneous integrated boost guided by MR spectroscopic imaging.
    BMC cancer, 2019, Feb-21, Volume: 19, Issue:1

    Topics: Adult; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Diagnostic Imaging; Gl

2019
Dose-painting multicenter phase III trial in newly diagnosed glioblastoma: the SPECTRO-GLIO trial comparing arm A standard radiochemotherapy to arm B radiochemotherapy with simultaneous integrated boost guided by MR spectroscopic imaging.
    BMC cancer, 2019, Feb-21, Volume: 19, Issue:1

    Topics: Adult; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Diagnostic Imaging; Gl

2019
Dose-painting multicenter phase III trial in newly diagnosed glioblastoma: the SPECTRO-GLIO trial comparing arm A standard radiochemotherapy to arm B radiochemotherapy with simultaneous integrated boost guided by MR spectroscopic imaging.
    BMC cancer, 2019, Feb-21, Volume: 19, Issue:1

    Topics: Adult; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Diagnostic Imaging; Gl

2019
Dose-painting multicenter phase III trial in newly diagnosed glioblastoma: the SPECTRO-GLIO trial comparing arm A standard radiochemotherapy to arm B radiochemotherapy with simultaneous integrated boost guided by MR spectroscopic imaging.
    BMC cancer, 2019, Feb-21, Volume: 19, Issue:1

    Topics: Adult; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Diagnostic Imaging; Gl

2019
Dose-painting multicenter phase III trial in newly diagnosed glioblastoma: the SPECTRO-GLIO trial comparing arm A standard radiochemotherapy to arm B radiochemotherapy with simultaneous integrated boost guided by MR spectroscopic imaging.
    BMC cancer, 2019, Feb-21, Volume: 19, Issue:1

    Topics: Adult; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Diagnostic Imaging; Gl

2019
Phase I/IIa study of concomitant radiotherapy with olaparib and temozolomide in unresectable or partially resectable glioblastoma: OLA-TMZ-RTE-01 trial protocol.
    BMC cancer, 2019, Mar-04, Volume: 19, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Glioblastoma; Humans; Phthala

2019
Phase I/IIa study of concomitant radiotherapy with olaparib and temozolomide in unresectable or partially resectable glioblastoma: OLA-TMZ-RTE-01 trial protocol.
    BMC cancer, 2019, Mar-04, Volume: 19, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Glioblastoma; Humans; Phthala

2019
Phase I/IIa study of concomitant radiotherapy with olaparib and temozolomide in unresectable or partially resectable glioblastoma: OLA-TMZ-RTE-01 trial protocol.
    BMC cancer, 2019, Mar-04, Volume: 19, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Glioblastoma; Humans; Phthala

2019
Phase I/IIa study of concomitant radiotherapy with olaparib and temozolomide in unresectable or partially resectable glioblastoma: OLA-TMZ-RTE-01 trial protocol.
    BMC cancer, 2019, Mar-04, Volume: 19, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Glioblastoma; Humans; Phthala

2019
Phase I/IIa study of concomitant radiotherapy with olaparib and temozolomide in unresectable or partially resectable glioblastoma: OLA-TMZ-RTE-01 trial protocol.
    BMC cancer, 2019, Mar-04, Volume: 19, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Glioblastoma; Humans; Phthala

2019
Phase I/IIa study of concomitant radiotherapy with olaparib and temozolomide in unresectable or partially resectable glioblastoma: OLA-TMZ-RTE-01 trial protocol.
    BMC cancer, 2019, Mar-04, Volume: 19, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Glioblastoma; Humans; Phthala

2019
Phase I/IIa study of concomitant radiotherapy with olaparib and temozolomide in unresectable or partially resectable glioblastoma: OLA-TMZ-RTE-01 trial protocol.
    BMC cancer, 2019, Mar-04, Volume: 19, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Glioblastoma; Humans; Phthala

2019
Phase I/IIa study of concomitant radiotherapy with olaparib and temozolomide in unresectable or partially resectable glioblastoma: OLA-TMZ-RTE-01 trial protocol.
    BMC cancer, 2019, Mar-04, Volume: 19, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Glioblastoma; Humans; Phthala

2019
Phase I/IIa study of concomitant radiotherapy with olaparib and temozolomide in unresectable or partially resectable glioblastoma: OLA-TMZ-RTE-01 trial protocol.
    BMC cancer, 2019, Mar-04, Volume: 19, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Glioblastoma; Humans; Phthala

2019
Phase I/IIa study of concomitant radiotherapy with olaparib and temozolomide in unresectable or partially resectable glioblastoma: OLA-TMZ-RTE-01 trial protocol.
    BMC cancer, 2019, Mar-04, Volume: 19, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Glioblastoma; Humans; Phthala

2019
Phase I/IIa study of concomitant radiotherapy with olaparib and temozolomide in unresectable or partially resectable glioblastoma: OLA-TMZ-RTE-01 trial protocol.
    BMC cancer, 2019, Mar-04, Volume: 19, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Glioblastoma; Humans; Phthala

2019
Phase I/IIa study of concomitant radiotherapy with olaparib and temozolomide in unresectable or partially resectable glioblastoma: OLA-TMZ-RTE-01 trial protocol.
    BMC cancer, 2019, Mar-04, Volume: 19, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Glioblastoma; Humans; Phthala

2019
Immune Phenotype Correlates With Survival in Patients With GBM Treated With Standard Temozolomide-based Therapy and Immunotherapy.
    Anticancer research, 2019, Volume: 39, Issue:4

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dendriti

2019
Immune Phenotype Correlates With Survival in Patients With GBM Treated With Standard Temozolomide-based Therapy and Immunotherapy.
    Anticancer research, 2019, Volume: 39, Issue:4

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dendriti

2019
Immune Phenotype Correlates With Survival in Patients With GBM Treated With Standard Temozolomide-based Therapy and Immunotherapy.
    Anticancer research, 2019, Volume: 39, Issue:4

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dendriti

2019
A Phase II Trial of Concurrent Temozolomide and Hypofractionated Stereotactic Radiotherapy for Complex Brain Metastases.
    The oncologist, 2019, Volume: 24, Issue:9

    Topics: Brain Neoplasms; Combined Modality Therapy; Disease-Free Survival; Dose Fractionation, Radiation; Dr

2019
A Phase II Trial of Concurrent Temozolomide and Hypofractionated Stereotactic Radiotherapy for Complex Brain Metastases.
    The oncologist, 2019, Volume: 24, Issue:9

    Topics: Brain Neoplasms; Combined Modality Therapy; Disease-Free Survival; Dose Fractionation, Radiation; Dr

2019
A Phase II Trial of Concurrent Temozolomide and Hypofractionated Stereotactic Radiotherapy for Complex Brain Metastases.
    The oncologist, 2019, Volume: 24, Issue:9

    Topics: Brain Neoplasms; Combined Modality Therapy; Disease-Free Survival; Dose Fractionation, Radiation; Dr

2019
Hypofractionated radiation therapy versus chemotherapy with temozolomide in patients affected by RPA class V and VI glioblastoma: a randomized phase II trial.
    Journal of neuro-oncology, 2019, Volume: 143, Issue:3

    Topics: Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Female; Follow-Up Studies; Glioblastoma; H

2019
Hypofractionated radiation therapy versus chemotherapy with temozolomide in patients affected by RPA class V and VI glioblastoma: a randomized phase II trial.
    Journal of neuro-oncology, 2019, Volume: 143, Issue:3

    Topics: Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Female; Follow-Up Studies; Glioblastoma; H

2019
Hypofractionated radiation therapy versus chemotherapy with temozolomide in patients affected by RPA class V and VI glioblastoma: a randomized phase II trial.
    Journal of neuro-oncology, 2019, Volume: 143, Issue:3

    Topics: Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Female; Follow-Up Studies; Glioblastoma; H

2019
A novel lecithin-based delivery form of Boswellic acids as complementary treatment of radiochemotherapy-induced cerebral edema in patients with glioblastoma multiforme: a longitudinal pilot experience.
    Journal of neurosurgical sciences, 2019, Volume: 63, Issue:3

    Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents, Alkylating; Brain Edema

2019
A novel lecithin-based delivery form of Boswellic acids as complementary treatment of radiochemotherapy-induced cerebral edema in patients with glioblastoma multiforme: a longitudinal pilot experience.
    Journal of neurosurgical sciences, 2019, Volume: 63, Issue:3

    Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents, Alkylating; Brain Edema

2019
A novel lecithin-based delivery form of Boswellic acids as complementary treatment of radiochemotherapy-induced cerebral edema in patients with glioblastoma multiforme: a longitudinal pilot experience.
    Journal of neurosurgical sciences, 2019, Volume: 63, Issue:3

    Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents, Alkylating; Brain Edema

2019
Hypofractionated radiation therapy and temozolomide in patients with glioblastoma and poor prognostic factors. A prospective, single-institution experience.
    PloS one, 2019, Volume: 14, Issue:6

    Topics: Aged; Brain Neoplasms; Factor Analysis, Statistical; Female; Glioblastoma; Humans; Magnetic Resonanc

2019
Hypofractionated radiation therapy and temozolomide in patients with glioblastoma and poor prognostic factors. A prospective, single-institution experience.
    PloS one, 2019, Volume: 14, Issue:6

    Topics: Aged; Brain Neoplasms; Factor Analysis, Statistical; Female; Glioblastoma; Humans; Magnetic Resonanc

2019
Hypofractionated radiation therapy and temozolomide in patients with glioblastoma and poor prognostic factors. A prospective, single-institution experience.
    PloS one, 2019, Volume: 14, Issue:6

    Topics: Aged; Brain Neoplasms; Factor Analysis, Statistical; Female; Glioblastoma; Humans; Magnetic Resonanc

2019
Efficacy of moderately hypofractionated simultaneous integrated boost intensity-modulated radiotherapy combined with temozolomide for the postoperative treatment of glioblastoma multiforme: a single-institution experience.
    Radiation oncology (London, England), 2019, Jun-13, Volume: 14, Issue:1

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Female; Glioblas

2019
Efficacy of moderately hypofractionated simultaneous integrated boost intensity-modulated radiotherapy combined with temozolomide for the postoperative treatment of glioblastoma multiforme: a single-institution experience.
    Radiation oncology (London, England), 2019, Jun-13, Volume: 14, Issue:1

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Female; Glioblas

2019
Efficacy of moderately hypofractionated simultaneous integrated boost intensity-modulated radiotherapy combined with temozolomide for the postoperative treatment of glioblastoma multiforme: a single-institution experience.
    Radiation oncology (London, England), 2019, Jun-13, Volume: 14, Issue:1

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Female; Glioblas

2019
Baseline T1 hyperintense and diffusion-restricted lesions are not linked to prolonged survival in bevacizumab-treated glioblastoma patients of the GLARIUS trial.
    Journal of neuro-oncology, 2019, Volume: 144, Issue:3

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Brain Neoplasms; Camptothe

2019
Baseline T1 hyperintense and diffusion-restricted lesions are not linked to prolonged survival in bevacizumab-treated glioblastoma patients of the GLARIUS trial.
    Journal of neuro-oncology, 2019, Volume: 144, Issue:3

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Brain Neoplasms; Camptothe

2019
Baseline T1 hyperintense and diffusion-restricted lesions are not linked to prolonged survival in bevacizumab-treated glioblastoma patients of the GLARIUS trial.
    Journal of neuro-oncology, 2019, Volume: 144, Issue:3

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Brain Neoplasms; Camptothe

2019
Report of first recurrent glioma patients examined with PET-MRI prior to re-irradiation.
    PloS one, 2019, Volume: 14, Issue:7

    Topics: Adolescent; Adult; Aged; Bevacizumab; Brain Neoplasms; Chemoradiotherapy; Female; Glioma; Humans; Ma

2019
Report of first recurrent glioma patients examined with PET-MRI prior to re-irradiation.
    PloS one, 2019, Volume: 14, Issue:7

    Topics: Adolescent; Adult; Aged; Bevacizumab; Brain Neoplasms; Chemoradiotherapy; Female; Glioma; Humans; Ma

2019
Report of first recurrent glioma patients examined with PET-MRI prior to re-irradiation.
    PloS one, 2019, Volume: 14, Issue:7

    Topics: Adolescent; Adult; Aged; Bevacizumab; Brain Neoplasms; Chemoradiotherapy; Female; Glioma; Humans; Ma

2019
Phase I study of hypofractionated intensity modulated radiation therapy with concurrent and adjuvant temozolomide in patients with glioblastoma multiforme.
    Radiation oncology (London, England), 2013, Feb-20, Volume: 8

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brachytherapy; Brain Neoplasms; Chemoradiotherapy; C

2013
Phase I study of hypofractionated intensity modulated radiation therapy with concurrent and adjuvant temozolomide in patients with glioblastoma multiforme.
    Radiation oncology (London, England), 2013, Feb-20, Volume: 8

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brachytherapy; Brain Neoplasms; Chemoradiotherapy; C

2013
Phase I study of hypofractionated intensity modulated radiation therapy with concurrent and adjuvant temozolomide in patients with glioblastoma multiforme.
    Radiation oncology (London, England), 2013, Feb-20, Volume: 8

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brachytherapy; Brain Neoplasms; Chemoradiotherapy; C

2013
A phase II single-arm study of irinotecan in combination with temozolomide (TEMIRI) in children with newly diagnosed high grade glioma: a joint ITCC and SIOPE-brain tumour study.
    Journal of neuro-oncology, 2013, Volume: 113, Issue:1

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Camptothecin; Child; Ch

2013
A phase II single-arm study of irinotecan in combination with temozolomide (TEMIRI) in children with newly diagnosed high grade glioma: a joint ITCC and SIOPE-brain tumour study.
    Journal of neuro-oncology, 2013, Volume: 113, Issue:1

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Camptothecin; Child; Ch

2013
A phase II single-arm study of irinotecan in combination with temozolomide (TEMIRI) in children with newly diagnosed high grade glioma: a joint ITCC and SIOPE-brain tumour study.
    Journal of neuro-oncology, 2013, Volume: 113, Issue:1

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Camptothecin; Child; Ch

2013
Secondary hematological malignancies associated with temozolomide in patients with glioma.
    Neuro-oncology, 2013, Volume: 15, Issue:10

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chil

2013
Secondary hematological malignancies associated with temozolomide in patients with glioma.
    Neuro-oncology, 2013, Volume: 15, Issue:10

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chil

2013
Secondary hematological malignancies associated with temozolomide in patients with glioma.
    Neuro-oncology, 2013, Volume: 15, Issue:10

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chil

2013
Phase 2 study of dose-intense temozolomide in recurrent glioblastoma.
    Neuro-oncology, 2013, Volume: 15, Issue:7

    Topics: Adaptor Proteins, Signal Transducing; Adult; Aged; Antineoplastic Agents, Alkylating; Biomarkers, Tu

2013
Phase 2 study of dose-intense temozolomide in recurrent glioblastoma.
    Neuro-oncology, 2013, Volume: 15, Issue:7

    Topics: Adaptor Proteins, Signal Transducing; Adult; Aged; Antineoplastic Agents, Alkylating; Biomarkers, Tu

2013
Phase 2 study of dose-intense temozolomide in recurrent glioblastoma.
    Neuro-oncology, 2013, Volume: 15, Issue:7

    Topics: Adaptor Proteins, Signal Transducing; Adult; Aged; Antineoplastic Agents, Alkylating; Biomarkers, Tu

2013
A pediatric phase 1 trial of vorinostat and temozolomide in relapsed or refractory primary brain or spinal cord tumors: a Children's Oncology Group phase 1 consortium study.
    Pediatric blood & cancer, 2013, Volume: 60, Issue:9

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Child; Child, Pr

2013
A pediatric phase 1 trial of vorinostat and temozolomide in relapsed or refractory primary brain or spinal cord tumors: a Children's Oncology Group phase 1 consortium study.
    Pediatric blood & cancer, 2013, Volume: 60, Issue:9

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Child; Child, Pr

2013
A pediatric phase 1 trial of vorinostat and temozolomide in relapsed or refractory primary brain or spinal cord tumors: a Children's Oncology Group phase 1 consortium study.
    Pediatric blood & cancer, 2013, Volume: 60, Issue:9

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Child; Child, Pr

2013
Pilot study of vincristine, oral irinotecan, and temozolomide (VOIT regimen) combined with bevacizumab in pediatric patients with recurrent solid tumors or brain tumors.
    Pediatric blood & cancer, 2013, Volume: 60, Issue:9

    Topics: Administration, Oral; Adolescent; Adult; Anti-Bacterial Agents; Antibodies, Monoclonal, Humanized; A

2013
Pilot study of vincristine, oral irinotecan, and temozolomide (VOIT regimen) combined with bevacizumab in pediatric patients with recurrent solid tumors or brain tumors.
    Pediatric blood & cancer, 2013, Volume: 60, Issue:9

    Topics: Administration, Oral; Adolescent; Adult; Anti-Bacterial Agents; Antibodies, Monoclonal, Humanized; A

2013
Pilot study of vincristine, oral irinotecan, and temozolomide (VOIT regimen) combined with bevacizumab in pediatric patients with recurrent solid tumors or brain tumors.
    Pediatric blood & cancer, 2013, Volume: 60, Issue:9

    Topics: Administration, Oral; Adolescent; Adult; Anti-Bacterial Agents; Antibodies, Monoclonal, Humanized; A

2013
Phase II trial of upfront bevacizumab and temozolomide for unresectable or multifocal glioblastoma.
    Cancer medicine, 2013, Volume: 2, Issue:2

    Topics: Adult; Aged; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Antineoplastic Agents, Alky

2013
Phase II trial of upfront bevacizumab and temozolomide for unresectable or multifocal glioblastoma.
    Cancer medicine, 2013, Volume: 2, Issue:2

    Topics: Adult; Aged; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Antineoplastic Agents, Alky

2013
Phase II trial of upfront bevacizumab and temozolomide for unresectable or multifocal glioblastoma.
    Cancer medicine, 2013, Volume: 2, Issue:2

    Topics: Adult; Aged; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Antineoplastic Agents, Alky

2013
Health-related quality of life in elderly patients with newly diagnosed glioblastoma treated with short-course radiation therapy plus concomitant and adjuvant temozolomide.
    International journal of radiation oncology, biology, physics, 2013, Jun-01, Volume: 86, Issue:2

    Topics: Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cognition; Combined Mod

2013
Health-related quality of life in elderly patients with newly diagnosed glioblastoma treated with short-course radiation therapy plus concomitant and adjuvant temozolomide.
    International journal of radiation oncology, biology, physics, 2013, Jun-01, Volume: 86, Issue:2

    Topics: Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cognition; Combined Mod

2013
Health-related quality of life in elderly patients with newly diagnosed glioblastoma treated with short-course radiation therapy plus concomitant and adjuvant temozolomide.
    International journal of radiation oncology, biology, physics, 2013, Jun-01, Volume: 86, Issue:2

    Topics: Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cognition; Combined Mod

2013
Magnetic resonance spectroscopy as an early indicator of response to anti-angiogenic therapy in patients with recurrent glioblastoma: RTOG 0625/ACRIN 6677.
    Neuro-oncology, 2013, Volume: 15, Issue:7

    Topics: Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Aspartic Acid; Be

2013
Magnetic resonance spectroscopy as an early indicator of response to anti-angiogenic therapy in patients with recurrent glioblastoma: RTOG 0625/ACRIN 6677.
    Neuro-oncology, 2013, Volume: 15, Issue:7

    Topics: Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Aspartic Acid; Be

2013
Magnetic resonance spectroscopy as an early indicator of response to anti-angiogenic therapy in patients with recurrent glioblastoma: RTOG 0625/ACRIN 6677.
    Neuro-oncology, 2013, Volume: 15, Issue:7

    Topics: Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Aspartic Acid; Be

2013
MGMT promoter methylation status and prognosis of patients with primary or recurrent glioblastoma treated with carmustine wafers.
    British journal of neurosurgery, 2013, Volume: 27, Issue:6

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Brai

2013
MGMT promoter methylation status and prognosis of patients with primary or recurrent glioblastoma treated with carmustine wafers.
    British journal of neurosurgery, 2013, Volume: 27, Issue:6

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Brai

2013
MGMT promoter methylation status and prognosis of patients with primary or recurrent glioblastoma treated with carmustine wafers.
    British journal of neurosurgery, 2013, Volume: 27, Issue:6

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Brai

2013
Phase I study of temozolomide combined with oral etoposide in children with malignant glial tumors.
    Journal of neuro-oncology, 2013, Volume: 113, Issue:3

    Topics: Administration, Oral; Adolescent; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; C

2013
Phase I study of temozolomide combined with oral etoposide in children with malignant glial tumors.
    Journal of neuro-oncology, 2013, Volume: 113, Issue:3

    Topics: Administration, Oral; Adolescent; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; C

2013
Phase I study of temozolomide combined with oral etoposide in children with malignant glial tumors.
    Journal of neuro-oncology, 2013, Volume: 113, Issue:3

    Topics: Administration, Oral; Adolescent; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; C

2013
RTOG 0913: a phase 1 study of daily everolimus (RAD001) in combination with radiation therapy and temozolomide in patients with newly diagnosed glioblastoma.
    International journal of radiation oncology, biology, physics, 2013, Aug-01, Volume: 86, Issue:5

    Topics: Administration, Oral; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms;

2013
RTOG 0913: a phase 1 study of daily everolimus (RAD001) in combination with radiation therapy and temozolomide in patients with newly diagnosed glioblastoma.
    International journal of radiation oncology, biology, physics, 2013, Aug-01, Volume: 86, Issue:5

    Topics: Administration, Oral; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms;

2013
RTOG 0913: a phase 1 study of daily everolimus (RAD001) in combination with radiation therapy and temozolomide in patients with newly diagnosed glioblastoma.
    International journal of radiation oncology, biology, physics, 2013, Aug-01, Volume: 86, Issue:5

    Topics: Administration, Oral; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms;

2013
Prospective evaluation of health-related quality of life in patients with glioblastoma multiforme treated on a phase II trial of hypofractionated IMRT with temozolomide.
    Journal of neuro-oncology, 2013, Volume: 114, Issue:1

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cognition; Combined Modality Therap

2013
Prospective evaluation of health-related quality of life in patients with glioblastoma multiforme treated on a phase II trial of hypofractionated IMRT with temozolomide.
    Journal of neuro-oncology, 2013, Volume: 114, Issue:1

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cognition; Combined Modality Therap

2013
Prospective evaluation of health-related quality of life in patients with glioblastoma multiforme treated on a phase II trial of hypofractionated IMRT with temozolomide.
    Journal of neuro-oncology, 2013, Volume: 114, Issue:1

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cognition; Combined Modality Therap

2013
Early post-bevacizumab progression on contrast-enhanced MRI as a prognostic marker for overall survival in recurrent glioblastoma: results from the ACRIN 6677/RTOG 0625 Central Reader Study.
    Neuro-oncology, 2013, Volume: 15, Issue:7

    Topics: Adult; Aged; Aged, 80 and over; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemother

2013
Early post-bevacizumab progression on contrast-enhanced MRI as a prognostic marker for overall survival in recurrent glioblastoma: results from the ACRIN 6677/RTOG 0625 Central Reader Study.
    Neuro-oncology, 2013, Volume: 15, Issue:7

    Topics: Adult; Aged; Aged, 80 and over; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemother

2013
Early post-bevacizumab progression on contrast-enhanced MRI as a prognostic marker for overall survival in recurrent glioblastoma: results from the ACRIN 6677/RTOG 0625 Central Reader Study.
    Neuro-oncology, 2013, Volume: 15, Issue:7

    Topics: Adult; Aged; Aged, 80 and over; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemother

2013
Continuous tamoxifen and dose-dense temozolomide in recurrent glioblastoma.
    Anticancer research, 2013, Volume: 33, Issue:8

    Topics: Adult; Aged; Antineoplastic Agents; Brain Neoplasms; Dacarbazine; Disease Progression; Dose-Response

2013
Continuous tamoxifen and dose-dense temozolomide in recurrent glioblastoma.
    Anticancer research, 2013, Volume: 33, Issue:8

    Topics: Adult; Aged; Antineoplastic Agents; Brain Neoplasms; Dacarbazine; Disease Progression; Dose-Response

2013
Continuous tamoxifen and dose-dense temozolomide in recurrent glioblastoma.
    Anticancer research, 2013, Volume: 33, Issue:8

    Topics: Adult; Aged; Antineoplastic Agents; Brain Neoplasms; Dacarbazine; Disease Progression; Dose-Response

2013
Sorafenib plus daily low-dose temozolomide for relapsed glioblastoma: a phase II study.
    Anticancer research, 2013, Volume: 33, Issue:8

    Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms;

2013
Sorafenib plus daily low-dose temozolomide for relapsed glioblastoma: a phase II study.
    Anticancer research, 2013, Volume: 33, Issue:8

    Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms;

2013
Sorafenib plus daily low-dose temozolomide for relapsed glioblastoma: a phase II study.
    Anticancer research, 2013, Volume: 33, Issue:8

    Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms;

2013
Temozolomide added to whole brain radiotherapy in patients with multiple brain metastases of non-small-cell lung cancer: a multicentric Austrian phase II study.
    Wiener klinische Wochenschrift, 2013, Volume: 125, Issue:15-16

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Austria; Brain Neoplasms; Carcinoma, Non-Small-Cell

2013
Temozolomide added to whole brain radiotherapy in patients with multiple brain metastases of non-small-cell lung cancer: a multicentric Austrian phase II study.
    Wiener klinische Wochenschrift, 2013, Volume: 125, Issue:15-16

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Austria; Brain Neoplasms; Carcinoma, Non-Small-Cell

2013
Temozolomide added to whole brain radiotherapy in patients with multiple brain metastases of non-small-cell lung cancer: a multicentric Austrian phase II study.
    Wiener klinische Wochenschrift, 2013, Volume: 125, Issue:15-16

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Austria; Brain Neoplasms; Carcinoma, Non-Small-Cell

2013
Concurrent and adjuvant temozolomide-based chemoradiotherapy schedules for glioblastoma. Hypotheses based on two prospective phase II trials.
    Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 2013, Volume: 189, Issue:11

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherap

2013
Concurrent and adjuvant temozolomide-based chemoradiotherapy schedules for glioblastoma. Hypotheses based on two prospective phase II trials.
    Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 2013, Volume: 189, Issue:11

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherap

2013
Concurrent and adjuvant temozolomide-based chemoradiotherapy schedules for glioblastoma. Hypotheses based on two prospective phase II trials.
    Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 2013, Volume: 189, Issue:11

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherap

2013
Phase I trial combining temozolomide plus lapatinib for the treatment of brain metastases in patients with HER2-positive metastatic breast cancer: the LAPTEM trial.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2013, Volume: 24, Issue:12

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Breast Neoplasms; Daca

2013
Phase I trial combining temozolomide plus lapatinib for the treatment of brain metastases in patients with HER2-positive metastatic breast cancer: the LAPTEM trial.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2013, Volume: 24, Issue:12

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Breast Neoplasms; Daca

2013
Phase I trial combining temozolomide plus lapatinib for the treatment of brain metastases in patients with HER2-positive metastatic breast cancer: the LAPTEM trial.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2013, Volume: 24, Issue:12

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Breast Neoplasms; Daca

2013
Clinical and Genetic Factors Associated With Severe Hematological Toxicity in Glioblastoma Patients During Radiation Plus Temozolomide Treatment: A Prospective Study.
    American journal of clinical oncology, 2015, Volume: 38, Issue:5

    Topics: Adult; Aged; Anticonvulsants; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy;

2015
Clinical and Genetic Factors Associated With Severe Hematological Toxicity in Glioblastoma Patients During Radiation Plus Temozolomide Treatment: A Prospective Study.
    American journal of clinical oncology, 2015, Volume: 38, Issue:5

    Topics: Adult; Aged; Anticonvulsants; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy;

2015
Clinical and Genetic Factors Associated With Severe Hematological Toxicity in Glioblastoma Patients During Radiation Plus Temozolomide Treatment: A Prospective Study.
    American journal of clinical oncology, 2015, Volume: 38, Issue:5

    Topics: Adult; Aged; Anticonvulsants; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy;

2015
Dose-dense temozolomide for newly diagnosed glioblastoma: a randomized phase III clinical trial.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2013, Nov-10, Volume: 31, Issue:32

    Topics: Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Dacarbazine; Disease-Fr

2013
Dose-dense temozolomide for newly diagnosed glioblastoma: a randomized phase III clinical trial.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2013, Nov-10, Volume: 31, Issue:32

    Topics: Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Dacarbazine; Disease-Fr

2013
Dose-dense temozolomide for newly diagnosed glioblastoma: a randomized phase III clinical trial.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2013, Nov-10, Volume: 31, Issue:32

    Topics: Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Dacarbazine; Disease-Fr

2013
Dose-dense temozolomide for newly diagnosed glioblastoma: a randomized phase III clinical trial.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2013, Nov-10, Volume: 31, Issue:32

    Topics: Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Dacarbazine; Disease-Fr

2013
Dose-dense temozolomide for newly diagnosed glioblastoma: a randomized phase III clinical trial.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2013, Nov-10, Volume: 31, Issue:32

    Topics: Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Dacarbazine; Disease-Fr

2013
Dose-dense temozolomide for newly diagnosed glioblastoma: a randomized phase III clinical trial.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2013, Nov-10, Volume: 31, Issue:32

    Topics: Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Dacarbazine; Disease-Fr

2013
Dose-dense temozolomide for newly diagnosed glioblastoma: a randomized phase III clinical trial.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2013, Nov-10, Volume: 31, Issue:32

    Topics: Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Dacarbazine; Disease-Fr

2013
Dose-dense temozolomide for newly diagnosed glioblastoma: a randomized phase III clinical trial.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2013, Nov-10, Volume: 31, Issue:32

    Topics: Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Dacarbazine; Disease-Fr

2013
Dose-dense temozolomide for newly diagnosed glioblastoma: a randomized phase III clinical trial.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2013, Nov-10, Volume: 31, Issue:32

    Topics: Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Dacarbazine; Disease-Fr

2013
Dose-dense temozolomide for newly diagnosed glioblastoma: a randomized phase III clinical trial.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2013, Nov-10, Volume: 31, Issue:32

    Topics: Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Dacarbazine; Disease-Fr

2013
Dose-dense temozolomide for newly diagnosed glioblastoma: a randomized phase III clinical trial.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2013, Nov-10, Volume: 31, Issue:32

    Topics: Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Dacarbazine; Disease-Fr

2013
Dose-dense temozolomide for newly diagnosed glioblastoma: a randomized phase III clinical trial.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2013, Nov-10, Volume: 31, Issue:32

    Topics: Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Dacarbazine; Disease-Fr

2013
Dose-dense temozolomide for newly diagnosed glioblastoma: a randomized phase III clinical trial.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2013, Nov-10, Volume: 31, Issue:32

    Topics: Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Dacarbazine; Disease-Fr

2013
Dose-dense temozolomide for newly diagnosed glioblastoma: a randomized phase III clinical trial.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2013, Nov-10, Volume: 31, Issue:32

    Topics: Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Dacarbazine; Disease-Fr

2013
Dose-dense temozolomide for newly diagnosed glioblastoma: a randomized phase III clinical trial.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2013, Nov-10, Volume: 31, Issue:32

    Topics: Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Dacarbazine; Disease-Fr

2013
Dose-dense temozolomide for newly diagnosed glioblastoma: a randomized phase III clinical trial.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2013, Nov-10, Volume: 31, Issue:32

    Topics: Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Dacarbazine; Disease-Fr

2013
Dose-dense temozolomide for newly diagnosed glioblastoma: a randomized phase III clinical trial.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2013, Nov-10, Volume: 31, Issue:32

    Topics: Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Dacarbazine; Disease-Fr

2013
Dose-dense temozolomide for newly diagnosed glioblastoma: a randomized phase III clinical trial.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2013, Nov-10, Volume: 31, Issue:32

    Topics: Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Dacarbazine; Disease-Fr

2013
Dose-dense temozolomide for newly diagnosed glioblastoma: a randomized phase III clinical trial.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2013, Nov-10, Volume: 31, Issue:32

    Topics: Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Dacarbazine; Disease-Fr

2013
Dose-dense temozolomide for newly diagnosed glioblastoma: a randomized phase III clinical trial.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2013, Nov-10, Volume: 31, Issue:32

    Topics: Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Dacarbazine; Disease-Fr

2013
Dose-dense temozolomide for newly diagnosed glioblastoma: a randomized phase III clinical trial.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2013, Nov-10, Volume: 31, Issue:32

    Topics: Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Dacarbazine; Disease-Fr

2013
Dose-dense temozolomide for newly diagnosed glioblastoma: a randomized phase III clinical trial.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2013, Nov-10, Volume: 31, Issue:32

    Topics: Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Dacarbazine; Disease-Fr

2013
Dose-dense temozolomide for newly diagnosed glioblastoma: a randomized phase III clinical trial.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2013, Nov-10, Volume: 31, Issue:32

    Topics: Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Dacarbazine; Disease-Fr

2013
Dose-dense temozolomide for newly diagnosed glioblastoma: a randomized phase III clinical trial.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2013, Nov-10, Volume: 31, Issue:32

    Topics: Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Dacarbazine; Disease-Fr

2013
Dose-dense temozolomide for newly diagnosed glioblastoma: a randomized phase III clinical trial.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2013, Nov-10, Volume: 31, Issue:32

    Topics: Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Dacarbazine; Disease-Fr

2013
Dose-dense temozolomide for newly diagnosed glioblastoma: a randomized phase III clinical trial.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2013, Nov-10, Volume: 31, Issue:32

    Topics: Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Dacarbazine; Disease-Fr

2013
Dose-dense temozolomide for newly diagnosed glioblastoma: a randomized phase III clinical trial.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2013, Nov-10, Volume: 31, Issue:32

    Topics: Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Dacarbazine; Disease-Fr

2013
Net clinical benefit analysis of radiation therapy oncology group 0525: a phase III trial comparing conventional adjuvant temozolomide with dose-intensive temozolomide in patients with newly diagnosed glioblastoma.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2013, Nov-10, Volume: 31, Issue:32

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherap

2013
Net clinical benefit analysis of radiation therapy oncology group 0525: a phase III trial comparing conventional adjuvant temozolomide with dose-intensive temozolomide in patients with newly diagnosed glioblastoma.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2013, Nov-10, Volume: 31, Issue:32

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherap

2013
Net clinical benefit analysis of radiation therapy oncology group 0525: a phase III trial comparing conventional adjuvant temozolomide with dose-intensive temozolomide in patients with newly diagnosed glioblastoma.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2013, Nov-10, Volume: 31, Issue:32

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherap

2013
Net clinical benefit analysis of radiation therapy oncology group 0525: a phase III trial comparing conventional adjuvant temozolomide with dose-intensive temozolomide in patients with newly diagnosed glioblastoma.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2013, Nov-10, Volume: 31, Issue:32

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherap

2013
Net clinical benefit analysis of radiation therapy oncology group 0525: a phase III trial comparing conventional adjuvant temozolomide with dose-intensive temozolomide in patients with newly diagnosed glioblastoma.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2013, Nov-10, Volume: 31, Issue:32

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherap

2013
Net clinical benefit analysis of radiation therapy oncology group 0525: a phase III trial comparing conventional adjuvant temozolomide with dose-intensive temozolomide in patients with newly diagnosed glioblastoma.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2013, Nov-10, Volume: 31, Issue:32

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherap

2013
Net clinical benefit analysis of radiation therapy oncology group 0525: a phase III trial comparing conventional adjuvant temozolomide with dose-intensive temozolomide in patients with newly diagnosed glioblastoma.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2013, Nov-10, Volume: 31, Issue:32

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherap

2013
Net clinical benefit analysis of radiation therapy oncology group 0525: a phase III trial comparing conventional adjuvant temozolomide with dose-intensive temozolomide in patients with newly diagnosed glioblastoma.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2013, Nov-10, Volume: 31, Issue:32

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherap

2013
Net clinical benefit analysis of radiation therapy oncology group 0525: a phase III trial comparing conventional adjuvant temozolomide with dose-intensive temozolomide in patients with newly diagnosed glioblastoma.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2013, Nov-10, Volume: 31, Issue:32

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherap

2013
Net clinical benefit analysis of radiation therapy oncology group 0525: a phase III trial comparing conventional adjuvant temozolomide with dose-intensive temozolomide in patients with newly diagnosed glioblastoma.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2013, Nov-10, Volume: 31, Issue:32

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherap

2013
Net clinical benefit analysis of radiation therapy oncology group 0525: a phase III trial comparing conventional adjuvant temozolomide with dose-intensive temozolomide in patients with newly diagnosed glioblastoma.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2013, Nov-10, Volume: 31, Issue:32

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherap

2013
Net clinical benefit analysis of radiation therapy oncology group 0525: a phase III trial comparing conventional adjuvant temozolomide with dose-intensive temozolomide in patients with newly diagnosed glioblastoma.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2013, Nov-10, Volume: 31, Issue:32

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherap

2013
Improved tumor oxygenation and survival in glioblastoma patients who show increased blood perfusion after cediranib and chemoradiation.
    Proceedings of the National Academy of Sciences of the United States of America, 2013, Nov-19, Volume: 110, Issue:47

    Topics: Angiogenesis Inhibitors; Biomarkers, Tumor; Brain Neoplasms; Dacarbazine; DNA Modification Methylase

2013
Improved tumor oxygenation and survival in glioblastoma patients who show increased blood perfusion after cediranib and chemoradiation.
    Proceedings of the National Academy of Sciences of the United States of America, 2013, Nov-19, Volume: 110, Issue:47

    Topics: Angiogenesis Inhibitors; Biomarkers, Tumor; Brain Neoplasms; Dacarbazine; DNA Modification Methylase

2013
Improved tumor oxygenation and survival in glioblastoma patients who show increased blood perfusion after cediranib and chemoradiation.
    Proceedings of the National Academy of Sciences of the United States of America, 2013, Nov-19, Volume: 110, Issue:47

    Topics: Angiogenesis Inhibitors; Biomarkers, Tumor; Brain Neoplasms; Dacarbazine; DNA Modification Methylase

2013
Gain of function of mutant TP53 in glioblastoma: prognosis and response to temozolomide.
    Annals of surgical oncology, 2014, Volume: 21, Issue:4

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; DNA Modification Methy

2014
Gain of function of mutant TP53 in glioblastoma: prognosis and response to temozolomide.
    Annals of surgical oncology, 2014, Volume: 21, Issue:4

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; DNA Modification Methy

2014
Gain of function of mutant TP53 in glioblastoma: prognosis and response to temozolomide.
    Annals of surgical oncology, 2014, Volume: 21, Issue:4

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; DNA Modification Methy

2014
Low incidence of pseudoprogression by imaging in newly diagnosed glioblastoma patients treated with cediranib in combination with chemoradiation.
    The oncologist, 2014, Volume: 19, Issue:1

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Chemoradiotherapy; Dac

2014
Low incidence of pseudoprogression by imaging in newly diagnosed glioblastoma patients treated with cediranib in combination with chemoradiation.
    The oncologist, 2014, Volume: 19, Issue:1

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Chemoradiotherapy; Dac

2014
Low incidence of pseudoprogression by imaging in newly diagnosed glioblastoma patients treated with cediranib in combination with chemoradiation.
    The oncologist, 2014, Volume: 19, Issue:1

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Chemoradiotherapy; Dac

2014
Low incidence of pseudoprogression by imaging in newly diagnosed glioblastoma patients treated with cediranib in combination with chemoradiation.
    The oncologist, 2014, Volume: 19, Issue:1

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Chemoradiotherapy; Dac

2014
Low incidence of pseudoprogression by imaging in newly diagnosed glioblastoma patients treated with cediranib in combination with chemoradiation.
    The oncologist, 2014, Volume: 19, Issue:1

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Chemoradiotherapy; Dac

2014
Low incidence of pseudoprogression by imaging in newly diagnosed glioblastoma patients treated with cediranib in combination with chemoradiation.
    The oncologist, 2014, Volume: 19, Issue:1

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Chemoradiotherapy; Dac

2014
Low incidence of pseudoprogression by imaging in newly diagnosed glioblastoma patients treated with cediranib in combination with chemoradiation.
    The oncologist, 2014, Volume: 19, Issue:1

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Chemoradiotherapy; Dac

2014
Low incidence of pseudoprogression by imaging in newly diagnosed glioblastoma patients treated with cediranib in combination with chemoradiation.
    The oncologist, 2014, Volume: 19, Issue:1

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Chemoradiotherapy; Dac

2014
Low incidence of pseudoprogression by imaging in newly diagnosed glioblastoma patients treated with cediranib in combination with chemoradiation.
    The oncologist, 2014, Volume: 19, Issue:1

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Chemoradiotherapy; Dac

2014
Low incidence of pseudoprogression by imaging in newly diagnosed glioblastoma patients treated with cediranib in combination with chemoradiation.
    The oncologist, 2014, Volume: 19, Issue:1

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Chemoradiotherapy; Dac

2014
Low incidence of pseudoprogression by imaging in newly diagnosed glioblastoma patients treated with cediranib in combination with chemoradiation.
    The oncologist, 2014, Volume: 19, Issue:1

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Chemoradiotherapy; Dac

2014
Low incidence of pseudoprogression by imaging in newly diagnosed glioblastoma patients treated with cediranib in combination with chemoradiation.
    The oncologist, 2014, Volume: 19, Issue:1

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Chemoradiotherapy; Dac

2014
Case numbers for a randomized clinical trial of boron neutron capture therapy for Glioblastoma multiforme.
    Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine, 2014, Volume: 88

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Borohydrides; Boron Compounds; Boron Neutron Capture

2014
Case numbers for a randomized clinical trial of boron neutron capture therapy for Glioblastoma multiforme.
    Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine, 2014, Volume: 88

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Borohydrides; Boron Compounds; Boron Neutron Capture

2014
Case numbers for a randomized clinical trial of boron neutron capture therapy for Glioblastoma multiforme.
    Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine, 2014, Volume: 88

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Borohydrides; Boron Compounds; Boron Neutron Capture

2014
Hypofractionated intensity modulated radiotherapy with temozolomide in newly diagnosed glioblastoma multiforme.
    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2014, Volume: 21, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Antineoplastic Protocols; Brain N

2014
Hypofractionated intensity modulated radiotherapy with temozolomide in newly diagnosed glioblastoma multiforme.
    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2014, Volume: 21, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Antineoplastic Protocols; Brain N

2014
Hypofractionated intensity modulated radiotherapy with temozolomide in newly diagnosed glioblastoma multiforme.
    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2014, Volume: 21, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Antineoplastic Protocols; Brain N

2014
Neoadjuvant cisplatin plus temozolomide versus standard treatment in patients with unresectable glioblastoma or anaplastic astrocytoma: a differential effect of MGMT methylation.
    Journal of neuro-oncology, 2014, Volume: 117, Issue:1

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neoplasms; Chemotherapy, Adjuvant

2014
Neoadjuvant cisplatin plus temozolomide versus standard treatment in patients with unresectable glioblastoma or anaplastic astrocytoma: a differential effect of MGMT methylation.
    Journal of neuro-oncology, 2014, Volume: 117, Issue:1

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neoplasms; Chemotherapy, Adjuvant

2014
Neoadjuvant cisplatin plus temozolomide versus standard treatment in patients with unresectable glioblastoma or anaplastic astrocytoma: a differential effect of MGMT methylation.
    Journal of neuro-oncology, 2014, Volume: 117, Issue:1

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neoplasms; Chemotherapy, Adjuvant

2014
Cilengitide treatment of newly diagnosed glioblastoma patients does not alter patterns of progression.
    Journal of neuro-oncology, 2014, Volume: 117, Issue:1

    Topics: Adult; Aged; Angiogenesis Inhibitors; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradio

2014
Cilengitide treatment of newly diagnosed glioblastoma patients does not alter patterns of progression.
    Journal of neuro-oncology, 2014, Volume: 117, Issue:1

    Topics: Adult; Aged; Angiogenesis Inhibitors; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradio

2014
Cilengitide treatment of newly diagnosed glioblastoma patients does not alter patterns of progression.
    Journal of neuro-oncology, 2014, Volume: 117, Issue:1

    Topics: Adult; Aged; Angiogenesis Inhibitors; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradio

2014
Neoadjuvant bevacizumab and irinotecan versus bevacizumab and temozolomide followed by concomitant chemoradiotherapy in newly diagnosed glioblastoma multiforme: A randomized phase II study.
    Acta oncologica (Stockholm, Sweden), 2014, Volume: 53, Issue:7

    Topics: Adult; Aged; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Beva

2014
Neoadjuvant bevacizumab and irinotecan versus bevacizumab and temozolomide followed by concomitant chemoradiotherapy in newly diagnosed glioblastoma multiforme: A randomized phase II study.
    Acta oncologica (Stockholm, Sweden), 2014, Volume: 53, Issue:7

    Topics: Adult; Aged; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Beva

2014
Neoadjuvant bevacizumab and irinotecan versus bevacizumab and temozolomide followed by concomitant chemoradiotherapy in newly diagnosed glioblastoma multiforme: A randomized phase II study.
    Acta oncologica (Stockholm, Sweden), 2014, Volume: 53, Issue:7

    Topics: Adult; Aged; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Beva

2014
Phase 2 trial of hypofractionated high-dose intensity modulated radiation therapy with concurrent and adjuvant temozolomide for newly diagnosed glioblastoma.
    International journal of radiation oncology, biology, physics, 2014, Mar-15, Volume: 88, Issue:4

    Topics: Antineoplastic Agents, Alkylating; Brain; Brain Neoplasms; Cause of Death; Chemotherapy, Adjuvant; D

2014
Phase 2 trial of hypofractionated high-dose intensity modulated radiation therapy with concurrent and adjuvant temozolomide for newly diagnosed glioblastoma.
    International journal of radiation oncology, biology, physics, 2014, Mar-15, Volume: 88, Issue:4

    Topics: Antineoplastic Agents, Alkylating; Brain; Brain Neoplasms; Cause of Death; Chemotherapy, Adjuvant; D

2014
Phase 2 trial of hypofractionated high-dose intensity modulated radiation therapy with concurrent and adjuvant temozolomide for newly diagnosed glioblastoma.
    International journal of radiation oncology, biology, physics, 2014, Mar-15, Volume: 88, Issue:4

    Topics: Antineoplastic Agents, Alkylating; Brain; Brain Neoplasms; Cause of Death; Chemotherapy, Adjuvant; D

2014
Bevacizumab plus radiotherapy-temozolomide for newly diagnosed glioblastoma.
    The New England journal of medicine, 2014, Feb-20, Volume: 370, Issue:8

    Topics: Adult; Aged; Aged, 80 and over; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Bevacizu

2014
Bevacizumab plus radiotherapy-temozolomide for newly diagnosed glioblastoma.
    The New England journal of medicine, 2014, Feb-20, Volume: 370, Issue:8

    Topics: Adult; Aged; Aged, 80 and over; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Bevacizu

2014
Bevacizumab plus radiotherapy-temozolomide for newly diagnosed glioblastoma.
    The New England journal of medicine, 2014, Feb-20, Volume: 370, Issue:8

    Topics: Adult; Aged; Aged, 80 and over; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Bevacizu

2014
Bevacizumab plus radiotherapy-temozolomide for newly diagnosed glioblastoma.
    The New England journal of medicine, 2014, Feb-20, Volume: 370, Issue:8

    Topics: Adult; Aged; Aged, 80 and over; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Bevacizu

2014
Bevacizumab plus radiotherapy-temozolomide for newly diagnosed glioblastoma.
    The New England journal of medicine, 2014, Feb-20, Volume: 370, Issue:8

    Topics: Adult; Aged; Aged, 80 and over; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Bevacizu

2014
Bevacizumab plus radiotherapy-temozolomide for newly diagnosed glioblastoma.
    The New England journal of medicine, 2014, Feb-20, Volume: 370, Issue:8

    Topics: Adult; Aged; Aged, 80 and over; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Bevacizu

2014
Bevacizumab plus radiotherapy-temozolomide for newly diagnosed glioblastoma.
    The New England journal of medicine, 2014, Feb-20, Volume: 370, Issue:8

    Topics: Adult; Aged; Aged, 80 and over; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Bevacizu

2014
Bevacizumab plus radiotherapy-temozolomide for newly diagnosed glioblastoma.
    The New England journal of medicine, 2014, Feb-20, Volume: 370, Issue:8

    Topics: Adult; Aged; Aged, 80 and over; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Bevacizu

2014
Bevacizumab plus radiotherapy-temozolomide for newly diagnosed glioblastoma.
    The New England journal of medicine, 2014, Feb-20, Volume: 370, Issue:8

    Topics: Adult; Aged; Aged, 80 and over; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Bevacizu

2014
Bevacizumab plus radiotherapy-temozolomide for newly diagnosed glioblastoma.
    The New England journal of medicine, 2014, Feb-20, Volume: 370, Issue:8

    Topics: Adult; Aged; Aged, 80 and over; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Bevacizu

2014
Bevacizumab plus radiotherapy-temozolomide for newly diagnosed glioblastoma.
    The New England journal of medicine, 2014, Feb-20, Volume: 370, Issue:8

    Topics: Adult; Aged; Aged, 80 and over; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Bevacizu

2014
Bevacizumab plus radiotherapy-temozolomide for newly diagnosed glioblastoma.
    The New England journal of medicine, 2014, Feb-20, Volume: 370, Issue:8

    Topics: Adult; Aged; Aged, 80 and over; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Bevacizu

2014
Bevacizumab plus radiotherapy-temozolomide for newly diagnosed glioblastoma.
    The New England journal of medicine, 2014, Feb-20, Volume: 370, Issue:8

    Topics: Adult; Aged; Aged, 80 and over; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Bevacizu

2014
Bevacizumab plus radiotherapy-temozolomide for newly diagnosed glioblastoma.
    The New England journal of medicine, 2014, Feb-20, Volume: 370, Issue:8

    Topics: Adult; Aged; Aged, 80 and over; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Bevacizu

2014
Bevacizumab plus radiotherapy-temozolomide for newly diagnosed glioblastoma.
    The New England journal of medicine, 2014, Feb-20, Volume: 370, Issue:8

    Topics: Adult; Aged; Aged, 80 and over; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Bevacizu

2014
Bevacizumab plus radiotherapy-temozolomide for newly diagnosed glioblastoma.
    The New England journal of medicine, 2014, Feb-20, Volume: 370, Issue:8

    Topics: Adult; Aged; Aged, 80 and over; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Bevacizu

2014
Bevacizumab plus radiotherapy-temozolomide for newly diagnosed glioblastoma.
    The New England journal of medicine, 2014, Feb-20, Volume: 370, Issue:8

    Topics: Adult; Aged; Aged, 80 and over; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Bevacizu

2014
Bevacizumab plus radiotherapy-temozolomide for newly diagnosed glioblastoma.
    The New England journal of medicine, 2014, Feb-20, Volume: 370, Issue:8

    Topics: Adult; Aged; Aged, 80 and over; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Bevacizu

2014
Bevacizumab plus radiotherapy-temozolomide for newly diagnosed glioblastoma.
    The New England journal of medicine, 2014, Feb-20, Volume: 370, Issue:8

    Topics: Adult; Aged; Aged, 80 and over; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Bevacizu

2014
Bevacizumab plus radiotherapy-temozolomide for newly diagnosed glioblastoma.
    The New England journal of medicine, 2014, Feb-20, Volume: 370, Issue:8

    Topics: Adult; Aged; Aged, 80 and over; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Bevacizu

2014
Bevacizumab plus radiotherapy-temozolomide for newly diagnosed glioblastoma.
    The New England journal of medicine, 2014, Feb-20, Volume: 370, Issue:8

    Topics: Adult; Aged; Aged, 80 and over; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Bevacizu

2014
Bevacizumab plus radiotherapy-temozolomide for newly diagnosed glioblastoma.
    The New England journal of medicine, 2014, Feb-20, Volume: 370, Issue:8

    Topics: Adult; Aged; Aged, 80 and over; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Bevacizu

2014
Bevacizumab plus radiotherapy-temozolomide for newly diagnosed glioblastoma.
    The New England journal of medicine, 2014, Feb-20, Volume: 370, Issue:8

    Topics: Adult; Aged; Aged, 80 and over; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Bevacizu

2014
Bevacizumab plus radiotherapy-temozolomide for newly diagnosed glioblastoma.
    The New England journal of medicine, 2014, Feb-20, Volume: 370, Issue:8

    Topics: Adult; Aged; Aged, 80 and over; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Bevacizu

2014
Bevacizumab plus radiotherapy-temozolomide for newly diagnosed glioblastoma.
    The New England journal of medicine, 2014, Feb-20, Volume: 370, Issue:8

    Topics: Adult; Aged; Aged, 80 and over; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Bevacizu

2014
Bevacizumab plus radiotherapy-temozolomide for newly diagnosed glioblastoma.
    The New England journal of medicine, 2014, Feb-20, Volume: 370, Issue:8

    Topics: Adult; Aged; Aged, 80 and over; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Bevacizu

2014
Bevacizumab plus radiotherapy-temozolomide for newly diagnosed glioblastoma.
    The New England journal of medicine, 2014, Feb-20, Volume: 370, Issue:8

    Topics: Adult; Aged; Aged, 80 and over; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Bevacizu

2014
Bevacizumab plus radiotherapy-temozolomide for newly diagnosed glioblastoma.
    The New England journal of medicine, 2014, Feb-20, Volume: 370, Issue:8

    Topics: Adult; Aged; Aged, 80 and over; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Bevacizu

2014
Bevacizumab plus radiotherapy-temozolomide for newly diagnosed glioblastoma.
    The New England journal of medicine, 2014, Feb-20, Volume: 370, Issue:8

    Topics: Adult; Aged; Aged, 80 and over; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Bevacizu

2014
Bevacizumab plus radiotherapy-temozolomide for newly diagnosed glioblastoma.
    The New England journal of medicine, 2014, Feb-20, Volume: 370, Issue:8

    Topics: Adult; Aged; Aged, 80 and over; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Bevacizu

2014
Bevacizumab plus radiotherapy-temozolomide for newly diagnosed glioblastoma.
    The New England journal of medicine, 2014, Feb-20, Volume: 370, Issue:8

    Topics: Adult; Aged; Aged, 80 and over; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Bevacizu

2014
Bevacizumab plus radiotherapy-temozolomide for newly diagnosed glioblastoma.
    The New England journal of medicine, 2014, Feb-20, Volume: 370, Issue:8

    Topics: Adult; Aged; Aged, 80 and over; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Bevacizu

2014
Bevacizumab plus radiotherapy-temozolomide for newly diagnosed glioblastoma.
    The New England journal of medicine, 2014, Feb-20, Volume: 370, Issue:8

    Topics: Adult; Aged; Aged, 80 and over; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Bevacizu

2014
Bevacizumab plus radiotherapy-temozolomide for newly diagnosed glioblastoma.
    The New England journal of medicine, 2014, Feb-20, Volume: 370, Issue:8

    Topics: Adult; Aged; Aged, 80 and over; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Bevacizu

2014
Bevacizumab plus radiotherapy-temozolomide for newly diagnosed glioblastoma.
    The New England journal of medicine, 2014, Feb-20, Volume: 370, Issue:8

    Topics: Adult; Aged; Aged, 80 and over; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Bevacizu

2014
Bevacizumab plus radiotherapy-temozolomide for newly diagnosed glioblastoma.
    The New England journal of medicine, 2014, Feb-20, Volume: 370, Issue:8

    Topics: Adult; Aged; Aged, 80 and over; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Bevacizu

2014
Bevacizumab plus radiotherapy-temozolomide for newly diagnosed glioblastoma.
    The New England journal of medicine, 2014, Feb-20, Volume: 370, Issue:8

    Topics: Adult; Aged; Aged, 80 and over; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Bevacizu

2014
Bevacizumab plus radiotherapy-temozolomide for newly diagnosed glioblastoma.
    The New England journal of medicine, 2014, Feb-20, Volume: 370, Issue:8

    Topics: Adult; Aged; Aged, 80 and over; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Bevacizu

2014
Bevacizumab plus radiotherapy-temozolomide for newly diagnosed glioblastoma.
    The New England journal of medicine, 2014, Feb-20, Volume: 370, Issue:8

    Topics: Adult; Aged; Aged, 80 and over; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Bevacizu

2014
Bevacizumab plus radiotherapy-temozolomide for newly diagnosed glioblastoma.
    The New England journal of medicine, 2014, Feb-20, Volume: 370, Issue:8

    Topics: Adult; Aged; Aged, 80 and over; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Bevacizu

2014
Bevacizumab plus radiotherapy-temozolomide for newly diagnosed glioblastoma.
    The New England journal of medicine, 2014, Feb-20, Volume: 370, Issue:8

    Topics: Adult; Aged; Aged, 80 and over; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Bevacizu

2014
Bevacizumab plus radiotherapy-temozolomide for newly diagnosed glioblastoma.
    The New England journal of medicine, 2014, Feb-20, Volume: 370, Issue:8

    Topics: Adult; Aged; Aged, 80 and over; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Bevacizu

2014
Bevacizumab plus radiotherapy-temozolomide for newly diagnosed glioblastoma.
    The New England journal of medicine, 2014, Feb-20, Volume: 370, Issue:8

    Topics: Adult; Aged; Aged, 80 and over; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Bevacizu

2014
Bevacizumab plus radiotherapy-temozolomide for newly diagnosed glioblastoma.
    The New England journal of medicine, 2014, Feb-20, Volume: 370, Issue:8

    Topics: Adult; Aged; Aged, 80 and over; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Bevacizu

2014
Bevacizumab plus radiotherapy-temozolomide for newly diagnosed glioblastoma.
    The New England journal of medicine, 2014, Feb-20, Volume: 370, Issue:8

    Topics: Adult; Aged; Aged, 80 and over; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Bevacizu

2014
Bevacizumab plus radiotherapy-temozolomide for newly diagnosed glioblastoma.
    The New England journal of medicine, 2014, Feb-20, Volume: 370, Issue:8

    Topics: Adult; Aged; Aged, 80 and over; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Bevacizu

2014
Bevacizumab plus radiotherapy-temozolomide for newly diagnosed glioblastoma.
    The New England journal of medicine, 2014, Feb-20, Volume: 370, Issue:8

    Topics: Adult; Aged; Aged, 80 and over; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Bevacizu

2014
Bevacizumab plus radiotherapy-temozolomide for newly diagnosed glioblastoma.
    The New England journal of medicine, 2014, Feb-20, Volume: 370, Issue:8

    Topics: Adult; Aged; Aged, 80 and over; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Bevacizu

2014
A randomized trial of bevacizumab for newly diagnosed glioblastoma.
    The New England journal of medicine, 2014, Feb-20, Volume: 370, Issue:8

    Topics: Adult; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Bevacizumab; Brain Neoplasms; Com

2014
A randomized trial of bevacizumab for newly diagnosed glioblastoma.
    The New England journal of medicine, 2014, Feb-20, Volume: 370, Issue:8

    Topics: Adult; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Bevacizumab; Brain Neoplasms; Com

2014
A randomized trial of bevacizumab for newly diagnosed glioblastoma.
    The New England journal of medicine, 2014, Feb-20, Volume: 370, Issue:8

    Topics: Adult; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Bevacizumab; Brain Neoplasms; Com

2014
A randomized trial of bevacizumab for newly diagnosed glioblastoma.
    The New England journal of medicine, 2014, Feb-20, Volume: 370, Issue:8

    Topics: Adult; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Bevacizumab; Brain Neoplasms; Com

2014
A randomized trial of bevacizumab for newly diagnosed glioblastoma.
    The New England journal of medicine, 2014, Feb-20, Volume: 370, Issue:8

    Topics: Adult; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Bevacizumab; Brain Neoplasms; Com

2014
A randomized trial of bevacizumab for newly diagnosed glioblastoma.
    The New England journal of medicine, 2014, Feb-20, Volume: 370, Issue:8

    Topics: Adult; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Bevacizumab; Brain Neoplasms; Com

2014
A randomized trial of bevacizumab for newly diagnosed glioblastoma.
    The New England journal of medicine, 2014, Feb-20, Volume: 370, Issue:8

    Topics: Adult; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Bevacizumab; Brain Neoplasms; Com

2014
A randomized trial of bevacizumab for newly diagnosed glioblastoma.
    The New England journal of medicine, 2014, Feb-20, Volume: 370, Issue:8

    Topics: Adult; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Bevacizumab; Brain Neoplasms; Com

2014
A randomized trial of bevacizumab for newly diagnosed glioblastoma.
    The New England journal of medicine, 2014, Feb-20, Volume: 370, Issue:8

    Topics: Adult; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Bevacizumab; Brain Neoplasms; Com

2014
A randomized trial of bevacizumab for newly diagnosed glioblastoma.
    The New England journal of medicine, 2014, Feb-20, Volume: 370, Issue:8

    Topics: Adult; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Bevacizumab; Brain Neoplasms; Com

2014
A randomized trial of bevacizumab for newly diagnosed glioblastoma.
    The New England journal of medicine, 2014, Feb-20, Volume: 370, Issue:8

    Topics: Adult; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Bevacizumab; Brain Neoplasms; Com

2014
A randomized trial of bevacizumab for newly diagnosed glioblastoma.
    The New England journal of medicine, 2014, Feb-20, Volume: 370, Issue:8

    Topics: Adult; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Bevacizumab; Brain Neoplasms; Com

2014
A randomized trial of bevacizumab for newly diagnosed glioblastoma.
    The New England journal of medicine, 2014, Feb-20, Volume: 370, Issue:8

    Topics: Adult; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Bevacizumab; Brain Neoplasms; Com

2014
A randomized trial of bevacizumab for newly diagnosed glioblastoma.
    The New England journal of medicine, 2014, Feb-20, Volume: 370, Issue:8

    Topics: Adult; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Bevacizumab; Brain Neoplasms; Com

2014
A randomized trial of bevacizumab for newly diagnosed glioblastoma.
    The New England journal of medicine, 2014, Feb-20, Volume: 370, Issue:8

    Topics: Adult; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Bevacizumab; Brain Neoplasms; Com

2014
A randomized trial of bevacizumab for newly diagnosed glioblastoma.
    The New England journal of medicine, 2014, Feb-20, Volume: 370, Issue:8

    Topics: Adult; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Bevacizumab; Brain Neoplasms; Com

2014
A randomized trial of bevacizumab for newly diagnosed glioblastoma.
    The New England journal of medicine, 2014, Feb-20, Volume: 370, Issue:8

    Topics: Adult; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Bevacizumab; Brain Neoplasms; Com

2014
A randomized trial of bevacizumab for newly diagnosed glioblastoma.
    The New England journal of medicine, 2014, Feb-20, Volume: 370, Issue:8

    Topics: Adult; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Bevacizumab; Brain Neoplasms; Com

2014
A randomized trial of bevacizumab for newly diagnosed glioblastoma.
    The New England journal of medicine, 2014, Feb-20, Volume: 370, Issue:8

    Topics: Adult; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Bevacizumab; Brain Neoplasms; Com

2014
A randomized trial of bevacizumab for newly diagnosed glioblastoma.
    The New England journal of medicine, 2014, Feb-20, Volume: 370, Issue:8

    Topics: Adult; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Bevacizumab; Brain Neoplasms; Com

2014
A randomized trial of bevacizumab for newly diagnosed glioblastoma.
    The New England journal of medicine, 2014, Feb-20, Volume: 370, Issue:8

    Topics: Adult; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Bevacizumab; Brain Neoplasms; Com

2014
A randomized trial of bevacizumab for newly diagnosed glioblastoma.
    The New England journal of medicine, 2014, Feb-20, Volume: 370, Issue:8

    Topics: Adult; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Bevacizumab; Brain Neoplasms; Com

2014
A randomized trial of bevacizumab for newly diagnosed glioblastoma.
    The New England journal of medicine, 2014, Feb-20, Volume: 370, Issue:8

    Topics: Adult; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Bevacizumab; Brain Neoplasms; Com

2014
A randomized trial of bevacizumab for newly diagnosed glioblastoma.
    The New England journal of medicine, 2014, Feb-20, Volume: 370, Issue:8

    Topics: Adult; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Bevacizumab; Brain Neoplasms; Com

2014
A randomized trial of bevacizumab for newly diagnosed glioblastoma.
    The New England journal of medicine, 2014, Feb-20, Volume: 370, Issue:8

    Topics: Adult; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Bevacizumab; Brain Neoplasms; Com

2014
A randomized trial of bevacizumab for newly diagnosed glioblastoma.
    The New England journal of medicine, 2014, Feb-20, Volume: 370, Issue:8

    Topics: Adult; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Bevacizumab; Brain Neoplasms; Com

2014
A randomized trial of bevacizumab for newly diagnosed glioblastoma.
    The New England journal of medicine, 2014, Feb-20, Volume: 370, Issue:8

    Topics: Adult; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Bevacizumab; Brain Neoplasms; Com

2014
A randomized trial of bevacizumab for newly diagnosed glioblastoma.
    The New England journal of medicine, 2014, Feb-20, Volume: 370, Issue:8

    Topics: Adult; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Bevacizumab; Brain Neoplasms; Com

2014
A randomized trial of bevacizumab for newly diagnosed glioblastoma.
    The New England journal of medicine, 2014, Feb-20, Volume: 370, Issue:8

    Topics: Adult; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Bevacizumab; Brain Neoplasms; Com

2014
A randomized trial of bevacizumab for newly diagnosed glioblastoma.
    The New England journal of medicine, 2014, Feb-20, Volume: 370, Issue:8

    Topics: Adult; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Bevacizumab; Brain Neoplasms; Com

2014
A randomized trial of bevacizumab for newly diagnosed glioblastoma.
    The New England journal of medicine, 2014, Feb-20, Volume: 370, Issue:8

    Topics: Adult; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Bevacizumab; Brain Neoplasms; Com

2014
A randomized trial of bevacizumab for newly diagnosed glioblastoma.
    The New England journal of medicine, 2014, Feb-20, Volume: 370, Issue:8

    Topics: Adult; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Bevacizumab; Brain Neoplasms; Com

2014
A randomized trial of bevacizumab for newly diagnosed glioblastoma.
    The New England journal of medicine, 2014, Feb-20, Volume: 370, Issue:8

    Topics: Adult; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Bevacizumab; Brain Neoplasms; Com

2014
A randomized trial of bevacizumab for newly diagnosed glioblastoma.
    The New England journal of medicine, 2014, Feb-20, Volume: 370, Issue:8

    Topics: Adult; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Bevacizumab; Brain Neoplasms; Com

2014
A randomized trial of bevacizumab for newly diagnosed glioblastoma.
    The New England journal of medicine, 2014, Feb-20, Volume: 370, Issue:8

    Topics: Adult; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Bevacizumab; Brain Neoplasms; Com

2014
A randomized trial of bevacizumab for newly diagnosed glioblastoma.
    The New England journal of medicine, 2014, Feb-20, Volume: 370, Issue:8

    Topics: Adult; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Bevacizumab; Brain Neoplasms; Com

2014
A randomized trial of bevacizumab for newly diagnosed glioblastoma.
    The New England journal of medicine, 2014, Feb-20, Volume: 370, Issue:8

    Topics: Adult; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Bevacizumab; Brain Neoplasms; Com

2014
A randomized trial of bevacizumab for newly diagnosed glioblastoma.
    The New England journal of medicine, 2014, Feb-20, Volume: 370, Issue:8

    Topics: Adult; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Bevacizumab; Brain Neoplasms; Com

2014
A randomized trial of bevacizumab for newly diagnosed glioblastoma.
    The New England journal of medicine, 2014, Feb-20, Volume: 370, Issue:8

    Topics: Adult; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Bevacizumab; Brain Neoplasms; Com

2014
A randomized trial of bevacizumab for newly diagnosed glioblastoma.
    The New England journal of medicine, 2014, Feb-20, Volume: 370, Issue:8

    Topics: Adult; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Bevacizumab; Brain Neoplasms; Com

2014
A randomized trial of bevacizumab for newly diagnosed glioblastoma.
    The New England journal of medicine, 2014, Feb-20, Volume: 370, Issue:8

    Topics: Adult; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Bevacizumab; Brain Neoplasms; Com

2014
A randomized trial of bevacizumab for newly diagnosed glioblastoma.
    The New England journal of medicine, 2014, Feb-20, Volume: 370, Issue:8

    Topics: Adult; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Bevacizumab; Brain Neoplasms; Com

2014
A randomized trial of bevacizumab for newly diagnosed glioblastoma.
    The New England journal of medicine, 2014, Feb-20, Volume: 370, Issue:8

    Topics: Adult; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Bevacizumab; Brain Neoplasms; Com

2014
A randomized trial of bevacizumab for newly diagnosed glioblastoma.
    The New England journal of medicine, 2014, Feb-20, Volume: 370, Issue:8

    Topics: Adult; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Bevacizumab; Brain Neoplasms; Com

2014
A randomized trial of bevacizumab for newly diagnosed glioblastoma.
    The New England journal of medicine, 2014, Feb-20, Volume: 370, Issue:8

    Topics: Adult; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Bevacizumab; Brain Neoplasms; Com

2014
A randomized trial of bevacizumab for newly diagnosed glioblastoma.
    The New England journal of medicine, 2014, Feb-20, Volume: 370, Issue:8

    Topics: Adult; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Bevacizumab; Brain Neoplasms; Com

2014
A randomized trial of bevacizumab for newly diagnosed glioblastoma.
    The New England journal of medicine, 2014, Feb-20, Volume: 370, Issue:8

    Topics: Adult; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Bevacizumab; Brain Neoplasms; Com

2014
A randomized trial of bevacizumab for newly diagnosed glioblastoma.
    The New England journal of medicine, 2014, Feb-20, Volume: 370, Issue:8

    Topics: Adult; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Bevacizumab; Brain Neoplasms; Com

2014
A randomized trial of bevacizumab for newly diagnosed glioblastoma.
    The New England journal of medicine, 2014, Feb-20, Volume: 370, Issue:8

    Topics: Adult; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Bevacizumab; Brain Neoplasms; Com

2014
A randomized trial of bevacizumab for newly diagnosed glioblastoma.
    The New England journal of medicine, 2014, Feb-20, Volume: 370, Issue:8

    Topics: Adult; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Bevacizumab; Brain Neoplasms; Com

2014
A randomized trial of bevacizumab for newly diagnosed glioblastoma.
    The New England journal of medicine, 2014, Feb-20, Volume: 370, Issue:8

    Topics: Adult; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Bevacizumab; Brain Neoplasms; Com

2014
A randomized trial of bevacizumab for newly diagnosed glioblastoma.
    The New England journal of medicine, 2014, Feb-20, Volume: 370, Issue:8

    Topics: Adult; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Bevacizumab; Brain Neoplasms; Com

2014
A randomized trial of bevacizumab for newly diagnosed glioblastoma.
    The New England journal of medicine, 2014, Feb-20, Volume: 370, Issue:8

    Topics: Adult; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Bevacizumab; Brain Neoplasms; Com

2014
A randomized trial of bevacizumab for newly diagnosed glioblastoma.
    The New England journal of medicine, 2014, Feb-20, Volume: 370, Issue:8

    Topics: Adult; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Bevacizumab; Brain Neoplasms; Com

2014
A randomized trial of bevacizumab for newly diagnosed glioblastoma.
    The New England journal of medicine, 2014, Feb-20, Volume: 370, Issue:8

    Topics: Adult; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Bevacizumab; Brain Neoplasms; Com

2014
A randomized trial of bevacizumab for newly diagnosed glioblastoma.
    The New England journal of medicine, 2014, Feb-20, Volume: 370, Issue:8

    Topics: Adult; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Bevacizumab; Brain Neoplasms; Com

2014
A randomized trial of bevacizumab for newly diagnosed glioblastoma.
    The New England journal of medicine, 2014, Feb-20, Volume: 370, Issue:8

    Topics: Adult; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Bevacizumab; Brain Neoplasms; Com

2014
A randomized trial of bevacizumab for newly diagnosed glioblastoma.
    The New England journal of medicine, 2014, Feb-20, Volume: 370, Issue:8

    Topics: Adult; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Bevacizumab; Brain Neoplasms; Com

2014
A randomized trial of bevacizumab for newly diagnosed glioblastoma.
    The New England journal of medicine, 2014, Feb-20, Volume: 370, Issue:8

    Topics: Adult; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Bevacizumab; Brain Neoplasms; Com

2014
A randomized trial of bevacizumab for newly diagnosed glioblastoma.
    The New England journal of medicine, 2014, Feb-20, Volume: 370, Issue:8

    Topics: Adult; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Bevacizumab; Brain Neoplasms; Com

2014
A randomized trial of bevacizumab for newly diagnosed glioblastoma.
    The New England journal of medicine, 2014, Feb-20, Volume: 370, Issue:8

    Topics: Adult; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Bevacizumab; Brain Neoplasms; Com

2014
A randomized trial of bevacizumab for newly diagnosed glioblastoma.
    The New England journal of medicine, 2014, Feb-20, Volume: 370, Issue:8

    Topics: Adult; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Bevacizumab; Brain Neoplasms; Com

2014
A randomized trial of bevacizumab for newly diagnosed glioblastoma.
    The New England journal of medicine, 2014, Feb-20, Volume: 370, Issue:8

    Topics: Adult; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Bevacizumab; Brain Neoplasms; Com

2014
A randomized trial of bevacizumab for newly diagnosed glioblastoma.
    The New England journal of medicine, 2014, Feb-20, Volume: 370, Issue:8

    Topics: Adult; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Bevacizumab; Brain Neoplasms; Com

2014
A randomized trial of bevacizumab for newly diagnosed glioblastoma.
    The New England journal of medicine, 2014, Feb-20, Volume: 370, Issue:8

    Topics: Adult; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Bevacizumab; Brain Neoplasms; Com

2014
A randomized trial of bevacizumab for newly diagnosed glioblastoma.
    The New England journal of medicine, 2014, Feb-20, Volume: 370, Issue:8

    Topics: Adult; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Bevacizumab; Brain Neoplasms; Com

2014
A randomized trial of bevacizumab for newly diagnosed glioblastoma.
    The New England journal of medicine, 2014, Feb-20, Volume: 370, Issue:8

    Topics: Adult; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Bevacizumab; Brain Neoplasms; Com

2014
A randomized trial of bevacizumab for newly diagnosed glioblastoma.
    The New England journal of medicine, 2014, Feb-20, Volume: 370, Issue:8

    Topics: Adult; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Bevacizumab; Brain Neoplasms; Com

2014
A randomized trial of bevacizumab for newly diagnosed glioblastoma.
    The New England journal of medicine, 2014, Feb-20, Volume: 370, Issue:8

    Topics: Adult; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Bevacizumab; Brain Neoplasms; Com

2014
A randomized trial of bevacizumab for newly diagnosed glioblastoma.
    The New England journal of medicine, 2014, Feb-20, Volume: 370, Issue:8

    Topics: Adult; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Bevacizumab; Brain Neoplasms; Com

2014
A randomized trial of bevacizumab for newly diagnosed glioblastoma.
    The New England journal of medicine, 2014, Feb-20, Volume: 370, Issue:8

    Topics: Adult; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Bevacizumab; Brain Neoplasms; Com

2014
A randomized trial of bevacizumab for newly diagnosed glioblastoma.
    The New England journal of medicine, 2014, Feb-20, Volume: 370, Issue:8

    Topics: Adult; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Bevacizumab; Brain Neoplasms; Com

2014
A randomized trial of bevacizumab for newly diagnosed glioblastoma.
    The New England journal of medicine, 2014, Feb-20, Volume: 370, Issue:8

    Topics: Adult; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Bevacizumab; Brain Neoplasms; Com

2014
A randomized trial of bevacizumab for newly diagnosed glioblastoma.
    The New England journal of medicine, 2014, Feb-20, Volume: 370, Issue:8

    Topics: Adult; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Bevacizumab; Brain Neoplasms; Com

2014
A randomized trial of bevacizumab for newly diagnosed glioblastoma.
    The New England journal of medicine, 2014, Feb-20, Volume: 370, Issue:8

    Topics: Adult; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Bevacizumab; Brain Neoplasms; Com

2014
A randomized trial of bevacizumab for newly diagnosed glioblastoma.
    The New England journal of medicine, 2014, Feb-20, Volume: 370, Issue:8

    Topics: Adult; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Bevacizumab; Brain Neoplasms; Com

2014
A randomized trial of bevacizumab for newly diagnosed glioblastoma.
    The New England journal of medicine, 2014, Feb-20, Volume: 370, Issue:8

    Topics: Adult; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Bevacizumab; Brain Neoplasms; Com

2014
A randomized trial of bevacizumab for newly diagnosed glioblastoma.
    The New England journal of medicine, 2014, Feb-20, Volume: 370, Issue:8

    Topics: Adult; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Bevacizumab; Brain Neoplasms; Com

2014
A randomized trial of bevacizumab for newly diagnosed glioblastoma.
    The New England journal of medicine, 2014, Feb-20, Volume: 370, Issue:8

    Topics: Adult; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Bevacizumab; Brain Neoplasms; Com

2014
A randomized trial of bevacizumab for newly diagnosed glioblastoma.
    The New England journal of medicine, 2014, Feb-20, Volume: 370, Issue:8

    Topics: Adult; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Bevacizumab; Brain Neoplasms; Com

2014
A randomized trial of bevacizumab for newly diagnosed glioblastoma.
    The New England journal of medicine, 2014, Feb-20, Volume: 370, Issue:8

    Topics: Adult; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Bevacizumab; Brain Neoplasms; Com

2014
A randomized trial of bevacizumab for newly diagnosed glioblastoma.
    The New England journal of medicine, 2014, Feb-20, Volume: 370, Issue:8

    Topics: Adult; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Bevacizumab; Brain Neoplasms; Com

2014
A randomized trial of bevacizumab for newly diagnosed glioblastoma.
    The New England journal of medicine, 2014, Feb-20, Volume: 370, Issue:8

    Topics: Adult; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Bevacizumab; Brain Neoplasms; Com

2014
A randomized trial of bevacizumab for newly diagnosed glioblastoma.
    The New England journal of medicine, 2014, Feb-20, Volume: 370, Issue:8

    Topics: Adult; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Bevacizumab; Brain Neoplasms; Com

2014
A randomized trial of bevacizumab for newly diagnosed glioblastoma.
    The New England journal of medicine, 2014, Feb-20, Volume: 370, Issue:8

    Topics: Adult; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Bevacizumab; Brain Neoplasms; Com

2014
A randomized trial of bevacizumab for newly diagnosed glioblastoma.
    The New England journal of medicine, 2014, Feb-20, Volume: 370, Issue:8

    Topics: Adult; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Bevacizumab; Brain Neoplasms; Com

2014
A randomized trial of bevacizumab for newly diagnosed glioblastoma.
    The New England journal of medicine, 2014, Feb-20, Volume: 370, Issue:8

    Topics: Adult; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Bevacizumab; Brain Neoplasms; Com

2014
A randomized trial of bevacizumab for newly diagnosed glioblastoma.
    The New England journal of medicine, 2014, Feb-20, Volume: 370, Issue:8

    Topics: Adult; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Bevacizumab; Brain Neoplasms; Com

2014
A randomized trial of bevacizumab for newly diagnosed glioblastoma.
    The New England journal of medicine, 2014, Feb-20, Volume: 370, Issue:8

    Topics: Adult; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Bevacizumab; Brain Neoplasms; Com

2014
A randomized trial of bevacizumab for newly diagnosed glioblastoma.
    The New England journal of medicine, 2014, Feb-20, Volume: 370, Issue:8

    Topics: Adult; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Bevacizumab; Brain Neoplasms; Com

2014
A randomized trial of bevacizumab for newly diagnosed glioblastoma.
    The New England journal of medicine, 2014, Feb-20, Volume: 370, Issue:8

    Topics: Adult; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Bevacizumab; Brain Neoplasms; Com

2014
A randomized trial of bevacizumab for newly diagnosed glioblastoma.
    The New England journal of medicine, 2014, Feb-20, Volume: 370, Issue:8

    Topics: Adult; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Bevacizumab; Brain Neoplasms; Com

2014
A randomized trial of bevacizumab for newly diagnosed glioblastoma.
    The New England journal of medicine, 2014, Feb-20, Volume: 370, Issue:8

    Topics: Adult; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Bevacizumab; Brain Neoplasms; Com

2014
A randomized trial of bevacizumab for newly diagnosed glioblastoma.
    The New England journal of medicine, 2014, Feb-20, Volume: 370, Issue:8

    Topics: Adult; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Bevacizumab; Brain Neoplasms; Com

2014
A randomized trial of bevacizumab for newly diagnosed glioblastoma.
    The New England journal of medicine, 2014, Feb-20, Volume: 370, Issue:8

    Topics: Adult; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Bevacizumab; Brain Neoplasms; Com

2014
A randomized trial of bevacizumab for newly diagnosed glioblastoma.
    The New England journal of medicine, 2014, Feb-20, Volume: 370, Issue:8

    Topics: Adult; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Bevacizumab; Brain Neoplasms; Com

2014
A randomized trial of bevacizumab for newly diagnosed glioblastoma.
    The New England journal of medicine, 2014, Feb-20, Volume: 370, Issue:8

    Topics: Adult; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Bevacizumab; Brain Neoplasms; Com

2014
A randomized trial of bevacizumab for newly diagnosed glioblastoma.
    The New England journal of medicine, 2014, Feb-20, Volume: 370, Issue:8

    Topics: Adult; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Bevacizumab; Brain Neoplasms; Com

2014
A randomized trial of bevacizumab for newly diagnosed glioblastoma.
    The New England journal of medicine, 2014, Feb-20, Volume: 370, Issue:8

    Topics: Adult; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Bevacizumab; Brain Neoplasms; Com

2014
A randomized trial of bevacizumab for newly diagnosed glioblastoma.
    The New England journal of medicine, 2014, Feb-20, Volume: 370, Issue:8

    Topics: Adult; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Bevacizumab; Brain Neoplasms; Com

2014
A randomized trial of bevacizumab for newly diagnosed glioblastoma.
    The New England journal of medicine, 2014, Feb-20, Volume: 370, Issue:8

    Topics: Adult; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Bevacizumab; Brain Neoplasms; Com

2014
A randomized trial of bevacizumab for newly diagnosed glioblastoma.
    The New England journal of medicine, 2014, Feb-20, Volume: 370, Issue:8

    Topics: Adult; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Bevacizumab; Brain Neoplasms; Com

2014
A randomized trial of bevacizumab for newly diagnosed glioblastoma.
    The New England journal of medicine, 2014, Feb-20, Volume: 370, Issue:8

    Topics: Adult; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Bevacizumab; Brain Neoplasms; Com

2014
A randomized trial of bevacizumab for newly diagnosed glioblastoma.
    The New England journal of medicine, 2014, Feb-20, Volume: 370, Issue:8

    Topics: Adult; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Bevacizumab; Brain Neoplasms; Com

2014
A randomized trial of bevacizumab for newly diagnosed glioblastoma.
    The New England journal of medicine, 2014, Feb-20, Volume: 370, Issue:8

    Topics: Adult; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Bevacizumab; Brain Neoplasms; Com

2014
A randomized trial of bevacizumab for newly diagnosed glioblastoma.
    The New England journal of medicine, 2014, Feb-20, Volume: 370, Issue:8

    Topics: Adult; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Bevacizumab; Brain Neoplasms; Com

2014
A randomized trial of bevacizumab for newly diagnosed glioblastoma.
    The New England journal of medicine, 2014, Feb-20, Volume: 370, Issue:8

    Topics: Adult; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Bevacizumab; Brain Neoplasms; Com

2014
A randomized trial of bevacizumab for newly diagnosed glioblastoma.
    The New England journal of medicine, 2014, Feb-20, Volume: 370, Issue:8

    Topics: Adult; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Bevacizumab; Brain Neoplasms; Com

2014
A randomized trial of bevacizumab for newly diagnosed glioblastoma.
    The New England journal of medicine, 2014, Feb-20, Volume: 370, Issue:8

    Topics: Adult; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Bevacizumab; Brain Neoplasms; Com

2014
A randomized trial of bevacizumab for newly diagnosed glioblastoma.
    The New England journal of medicine, 2014, Feb-20, Volume: 370, Issue:8

    Topics: Adult; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Bevacizumab; Brain Neoplasms; Com

2014
A randomized trial of bevacizumab for newly diagnosed glioblastoma.
    The New England journal of medicine, 2014, Feb-20, Volume: 370, Issue:8

    Topics: Adult; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Bevacizumab; Brain Neoplasms; Com

2014
A randomized trial of bevacizumab for newly diagnosed glioblastoma.
    The New England journal of medicine, 2014, Feb-20, Volume: 370, Issue:8

    Topics: Adult; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Bevacizumab; Brain Neoplasms; Com

2014
A randomized trial of bevacizumab for newly diagnosed glioblastoma.
    The New England journal of medicine, 2014, Feb-20, Volume: 370, Issue:8

    Topics: Adult; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Bevacizumab; Brain Neoplasms; Com

2014
A randomized trial of bevacizumab for newly diagnosed glioblastoma.
    The New England journal of medicine, 2014, Feb-20, Volume: 370, Issue:8

    Topics: Adult; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Bevacizumab; Brain Neoplasms; Com

2014
A randomized trial of bevacizumab for newly diagnosed glioblastoma.
    The New England journal of medicine, 2014, Feb-20, Volume: 370, Issue:8

    Topics: Adult; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Bevacizumab; Brain Neoplasms; Com

2014
A randomized trial of bevacizumab for newly diagnosed glioblastoma.
    The New England journal of medicine, 2014, Feb-20, Volume: 370, Issue:8

    Topics: Adult; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Bevacizumab; Brain Neoplasms; Com

2014
A randomized trial of bevacizumab for newly diagnosed glioblastoma.
    The New England journal of medicine, 2014, Feb-20, Volume: 370, Issue:8

    Topics: Adult; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Bevacizumab; Brain Neoplasms; Com

2014
A randomized trial of bevacizumab for newly diagnosed glioblastoma.
    The New England journal of medicine, 2014, Feb-20, Volume: 370, Issue:8

    Topics: Adult; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Bevacizumab; Brain Neoplasms; Com

2014
A randomized trial of bevacizumab for newly diagnosed glioblastoma.
    The New England journal of medicine, 2014, Feb-20, Volume: 370, Issue:8

    Topics: Adult; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Bevacizumab; Brain Neoplasms; Com

2014
A randomized trial of bevacizumab for newly diagnosed glioblastoma.
    The New England journal of medicine, 2014, Feb-20, Volume: 370, Issue:8

    Topics: Adult; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Bevacizumab; Brain Neoplasms; Com

2014
A randomized trial of bevacizumab for newly diagnosed glioblastoma.
    The New England journal of medicine, 2014, Feb-20, Volume: 370, Issue:8

    Topics: Adult; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Bevacizumab; Brain Neoplasms; Com

2014
A randomized trial of bevacizumab for newly diagnosed glioblastoma.
    The New England journal of medicine, 2014, Feb-20, Volume: 370, Issue:8

    Topics: Adult; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Bevacizumab; Brain Neoplasms; Com

2014
A randomized trial of bevacizumab for newly diagnosed glioblastoma.
    The New England journal of medicine, 2014, Feb-20, Volume: 370, Issue:8

    Topics: Adult; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Bevacizumab; Brain Neoplasms; Com

2014
A randomized trial of bevacizumab for newly diagnosed glioblastoma.
    The New England journal of medicine, 2014, Feb-20, Volume: 370, Issue:8

    Topics: Adult; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Bevacizumab; Brain Neoplasms; Com

2014
A randomized trial of bevacizumab for newly diagnosed glioblastoma.
    The New England journal of medicine, 2014, Feb-20, Volume: 370, Issue:8

    Topics: Adult; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Bevacizumab; Brain Neoplasms; Com

2014
A randomized trial of bevacizumab for newly diagnosed glioblastoma.
    The New England journal of medicine, 2014, Feb-20, Volume: 370, Issue:8

    Topics: Adult; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Bevacizumab; Brain Neoplasms; Com

2014
A randomized trial of bevacizumab for newly diagnosed glioblastoma.
    The New England journal of medicine, 2014, Feb-20, Volume: 370, Issue:8

    Topics: Adult; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Bevacizumab; Brain Neoplasms; Com

2014
A randomized trial of bevacizumab for newly diagnosed glioblastoma.
    The New England journal of medicine, 2014, Feb-20, Volume: 370, Issue:8

    Topics: Adult; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Bevacizumab; Brain Neoplasms; Com

2014
A randomized trial of bevacizumab for newly diagnosed glioblastoma.
    The New England journal of medicine, 2014, Feb-20, Volume: 370, Issue:8

    Topics: Adult; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Bevacizumab; Brain Neoplasms; Com

2014
A randomized trial of bevacizumab for newly diagnosed glioblastoma.
    The New England journal of medicine, 2014, Feb-20, Volume: 370, Issue:8

    Topics: Adult; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Bevacizumab; Brain Neoplasms; Com

2014
A randomized trial of bevacizumab for newly diagnosed glioblastoma.
    The New England journal of medicine, 2014, Feb-20, Volume: 370, Issue:8

    Topics: Adult; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Bevacizumab; Brain Neoplasms; Com

2014
A randomized trial of bevacizumab for newly diagnosed glioblastoma.
    The New England journal of medicine, 2014, Feb-20, Volume: 370, Issue:8

    Topics: Adult; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Bevacizumab; Brain Neoplasms; Com

2014
A randomized trial of bevacizumab for newly diagnosed glioblastoma.
    The New England journal of medicine, 2014, Feb-20, Volume: 370, Issue:8

    Topics: Adult; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Bevacizumab; Brain Neoplasms; Com

2014
A randomized trial of bevacizumab for newly diagnosed glioblastoma.
    The New England journal of medicine, 2014, Feb-20, Volume: 370, Issue:8

    Topics: Adult; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Bevacizumab; Brain Neoplasms; Com

2014
A randomized trial of bevacizumab for newly diagnosed glioblastoma.
    The New England journal of medicine, 2014, Feb-20, Volume: 370, Issue:8

    Topics: Adult; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Bevacizumab; Brain Neoplasms; Com

2014
A randomized trial of bevacizumab for newly diagnosed glioblastoma.
    The New England journal of medicine, 2014, Feb-20, Volume: 370, Issue:8

    Topics: Adult; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Bevacizumab; Brain Neoplasms; Com

2014
A randomized trial of bevacizumab for newly diagnosed glioblastoma.
    The New England journal of medicine, 2014, Feb-20, Volume: 370, Issue:8

    Topics: Adult; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Bevacizumab; Brain Neoplasms; Com

2014
A randomized trial of bevacizumab for newly diagnosed glioblastoma.
    The New England journal of medicine, 2014, Feb-20, Volume: 370, Issue:8

    Topics: Adult; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Bevacizumab; Brain Neoplasms; Com

2014
A randomized trial of bevacizumab for newly diagnosed glioblastoma.
    The New England journal of medicine, 2014, Feb-20, Volume: 370, Issue:8

    Topics: Adult; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Bevacizumab; Brain Neoplasms; Com

2014
A randomized trial of bevacizumab for newly diagnosed glioblastoma.
    The New England journal of medicine, 2014, Feb-20, Volume: 370, Issue:8

    Topics: Adult; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Bevacizumab; Brain Neoplasms; Com

2014
A randomized trial of bevacizumab for newly diagnosed glioblastoma.
    The New England journal of medicine, 2014, Feb-20, Volume: 370, Issue:8

    Topics: Adult; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Bevacizumab; Brain Neoplasms; Com

2014
A randomized trial of bevacizumab for newly diagnosed glioblastoma.
    The New England journal of medicine, 2014, Feb-20, Volume: 370, Issue:8

    Topics: Adult; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Bevacizumab; Brain Neoplasms; Com

2014
A randomized trial of bevacizumab for newly diagnosed glioblastoma.
    The New England journal of medicine, 2014, Feb-20, Volume: 370, Issue:8

    Topics: Adult; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Bevacizumab; Brain Neoplasms; Com

2014
A randomized trial of bevacizumab for newly diagnosed glioblastoma.
    The New England journal of medicine, 2014, Feb-20, Volume: 370, Issue:8

    Topics: Adult; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Bevacizumab; Brain Neoplasms; Com

2014
A randomized trial of bevacizumab for newly diagnosed glioblastoma.
    The New England journal of medicine, 2014, Feb-20, Volume: 370, Issue:8

    Topics: Adult; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Bevacizumab; Brain Neoplasms; Com

2014
A randomized trial of bevacizumab for newly diagnosed glioblastoma.
    The New England journal of medicine, 2014, Feb-20, Volume: 370, Issue:8

    Topics: Adult; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Bevacizumab; Brain Neoplasms; Com

2014
A randomized trial of bevacizumab for newly diagnosed glioblastoma.
    The New England journal of medicine, 2014, Feb-20, Volume: 370, Issue:8

    Topics: Adult; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Bevacizumab; Brain Neoplasms; Com

2014
Nimotuzumab, a humanized monoclonal antibody specific for the EGFR, in combination with temozolomide and radiation therapy for newly diagnosed glioblastoma multiforme: First results in Chinese patients.
    Asia-Pacific journal of clinical oncology, 2016, Volume: 12, Issue:1

    Topics: Adult; Aged; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Asia

2016
Nimotuzumab, a humanized monoclonal antibody specific for the EGFR, in combination with temozolomide and radiation therapy for newly diagnosed glioblastoma multiforme: First results in Chinese patients.
    Asia-Pacific journal of clinical oncology, 2016, Volume: 12, Issue:1

    Topics: Adult; Aged; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Asia

2016
Nimotuzumab, a humanized monoclonal antibody specific for the EGFR, in combination with temozolomide and radiation therapy for newly diagnosed glioblastoma multiforme: First results in Chinese patients.
    Asia-Pacific journal of clinical oncology, 2016, Volume: 12, Issue:1

    Topics: Adult; Aged; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Asia

2016
A single-institution phase II trial of radiation, temozolomide, erlotinib, and bevacizumab for initial treatment of glioblastoma.
    Neuro-oncology, 2014, Volume: 16, Issue:7

    Topics: Adult; Aged; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Beva

2014
A single-institution phase II trial of radiation, temozolomide, erlotinib, and bevacizumab for initial treatment of glioblastoma.
    Neuro-oncology, 2014, Volume: 16, Issue:7

    Topics: Adult; Aged; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Beva

2014
A single-institution phase II trial of radiation, temozolomide, erlotinib, and bevacizumab for initial treatment of glioblastoma.
    Neuro-oncology, 2014, Volume: 16, Issue:7

    Topics: Adult; Aged; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Beva

2014
Phase II trial of 7 days on/7 days off temozolmide for recurrent high-grade glioma.
    Neuro-oncology, 2014, Volume: 16, Issue:9

    Topics: Adult; Aged; Antibodies, Monoclonal, Humanized; Antineoplastic Agents, Alkylating; Bevacizumab; Brai

2014
Phase II trial of 7 days on/7 days off temozolmide for recurrent high-grade glioma.
    Neuro-oncology, 2014, Volume: 16, Issue:9

    Topics: Adult; Aged; Antibodies, Monoclonal, Humanized; Antineoplastic Agents, Alkylating; Bevacizumab; Brai

2014
Phase II trial of 7 days on/7 days off temozolmide for recurrent high-grade glioma.
    Neuro-oncology, 2014, Volume: 16, Issue:9

    Topics: Adult; Aged; Antibodies, Monoclonal, Humanized; Antineoplastic Agents, Alkylating; Bevacizumab; Brai

2014
Whole brain reirradiation and concurrent temozolomide in patients with brain metastases.
    Journal of neuro-oncology, 2014, Volume: 118, Issue:2

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Breast Neoplasms; Carcinoma; Carcin

2014
Whole brain reirradiation and concurrent temozolomide in patients with brain metastases.
    Journal of neuro-oncology, 2014, Volume: 118, Issue:2

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Breast Neoplasms; Carcinoma; Carcin

2014
Whole brain reirradiation and concurrent temozolomide in patients with brain metastases.
    Journal of neuro-oncology, 2014, Volume: 118, Issue:2

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Breast Neoplasms; Carcinoma; Carcin

2014
Randomized phase II trial of irinotecan and bevacizumab as neo-adjuvant and adjuvant to temozolomide-based chemoradiation compared with temozolomide-chemoradiation for unresectable glioblastoma: final results of the TEMAVIR study from ANOCEF†.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2014, Volume: 25, Issue:7

    Topics: Adult; Aged; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Beva

2014
Randomized phase II trial of irinotecan and bevacizumab as neo-adjuvant and adjuvant to temozolomide-based chemoradiation compared with temozolomide-chemoradiation for unresectable glioblastoma: final results of the TEMAVIR study from ANOCEF†.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2014, Volume: 25, Issue:7

    Topics: Adult; Aged; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Beva

2014
Randomized phase II trial of irinotecan and bevacizumab as neo-adjuvant and adjuvant to temozolomide-based chemoradiation compared with temozolomide-chemoradiation for unresectable glioblastoma: final results of the TEMAVIR study from ANOCEF†.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2014, Volume: 25, Issue:7

    Topics: Adult; Aged; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Beva

2014
Randomized phase II trial of irinotecan and bevacizumab as neo-adjuvant and adjuvant to temozolomide-based chemoradiation compared with temozolomide-chemoradiation for unresectable glioblastoma: final results of the TEMAVIR study from ANOCEF†.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2014, Volume: 25, Issue:7

    Topics: Adult; Aged; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Beva

2014
Randomized phase II trial of irinotecan and bevacizumab as neo-adjuvant and adjuvant to temozolomide-based chemoradiation compared with temozolomide-chemoradiation for unresectable glioblastoma: final results of the TEMAVIR study from ANOCEF†.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2014, Volume: 25, Issue:7

    Topics: Adult; Aged; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Beva

2014
Randomized phase II trial of irinotecan and bevacizumab as neo-adjuvant and adjuvant to temozolomide-based chemoradiation compared with temozolomide-chemoradiation for unresectable glioblastoma: final results of the TEMAVIR study from ANOCEF†.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2014, Volume: 25, Issue:7

    Topics: Adult; Aged; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Beva

2014
Randomized phase II trial of irinotecan and bevacizumab as neo-adjuvant and adjuvant to temozolomide-based chemoradiation compared with temozolomide-chemoradiation for unresectable glioblastoma: final results of the TEMAVIR study from ANOCEF†.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2014, Volume: 25, Issue:7

    Topics: Adult; Aged; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Beva

2014
Randomized phase II trial of irinotecan and bevacizumab as neo-adjuvant and adjuvant to temozolomide-based chemoradiation compared with temozolomide-chemoradiation for unresectable glioblastoma: final results of the TEMAVIR study from ANOCEF†.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2014, Volume: 25, Issue:7

    Topics: Adult; Aged; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Beva

2014
Randomized phase II trial of irinotecan and bevacizumab as neo-adjuvant and adjuvant to temozolomide-based chemoradiation compared with temozolomide-chemoradiation for unresectable glioblastoma: final results of the TEMAVIR study from ANOCEF†.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2014, Volume: 25, Issue:7

    Topics: Adult; Aged; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Beva

2014
Randomized phase II trial of irinotecan and bevacizumab as neo-adjuvant and adjuvant to temozolomide-based chemoradiation compared with temozolomide-chemoradiation for unresectable glioblastoma: final results of the TEMAVIR study from ANOCEF†.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2014, Volume: 25, Issue:7

    Topics: Adult; Aged; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Beva

2014
Randomized phase II trial of irinotecan and bevacizumab as neo-adjuvant and adjuvant to temozolomide-based chemoradiation compared with temozolomide-chemoradiation for unresectable glioblastoma: final results of the TEMAVIR study from ANOCEF†.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2014, Volume: 25, Issue:7

    Topics: Adult; Aged; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Beva

2014
Randomized phase II trial of irinotecan and bevacizumab as neo-adjuvant and adjuvant to temozolomide-based chemoradiation compared with temozolomide-chemoradiation for unresectable glioblastoma: final results of the TEMAVIR study from ANOCEF†.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2014, Volume: 25, Issue:7

    Topics: Adult; Aged; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Beva

2014
Phase I study of sorafenib combined with radiation therapy and temozolomide as first-line treatment of high-grade glioma.
    British journal of cancer, 2014, 05-27, Volume: 110, Issue:11

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Chemoradiotherapy; Dac

2014
Phase I study of sorafenib combined with radiation therapy and temozolomide as first-line treatment of high-grade glioma.
    British journal of cancer, 2014, 05-27, Volume: 110, Issue:11

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Chemoradiotherapy; Dac

2014
Phase I study of sorafenib combined with radiation therapy and temozolomide as first-line treatment of high-grade glioma.
    British journal of cancer, 2014, 05-27, Volume: 110, Issue:11

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Chemoradiotherapy; Dac

2014
Chemotherapy alleviates subacute recurrent glioma-associated refractory cerebral edema by downregulating vascular endothelial growth factor.
    Medical oncology (Northwood, London, England), 2014, Volume: 31, Issue:7

    Topics: Adult; Aged; Brain Edema; Brain Neoplasms; Cisplatin; Dacarbazine; Down-Regulation; Female; Glioma;

2014
Chemotherapy alleviates subacute recurrent glioma-associated refractory cerebral edema by downregulating vascular endothelial growth factor.
    Medical oncology (Northwood, London, England), 2014, Volume: 31, Issue:7

    Topics: Adult; Aged; Brain Edema; Brain Neoplasms; Cisplatin; Dacarbazine; Down-Regulation; Female; Glioma;

2014
Chemotherapy alleviates subacute recurrent glioma-associated refractory cerebral edema by downregulating vascular endothelial growth factor.
    Medical oncology (Northwood, London, England), 2014, Volume: 31, Issue:7

    Topics: Adult; Aged; Brain Edema; Brain Neoplasms; Cisplatin; Dacarbazine; Down-Regulation; Female; Glioma;

2014
A phase I trial of veliparib (ABT-888) and temozolomide in children with recurrent CNS tumors: a pediatric brain tumor consortium report.
    Neuro-oncology, 2014, Volume: 16, Issue:12

    Topics: Adolescent; Adult; Antineoplastic Agents, Alkylating; Benzimidazoles; Brain Neoplasms; Child; Child,

2014
A phase I trial of veliparib (ABT-888) and temozolomide in children with recurrent CNS tumors: a pediatric brain tumor consortium report.
    Neuro-oncology, 2014, Volume: 16, Issue:12

    Topics: Adolescent; Adult; Antineoplastic Agents, Alkylating; Benzimidazoles; Brain Neoplasms; Child; Child,

2014
A phase I trial of veliparib (ABT-888) and temozolomide in children with recurrent CNS tumors: a pediatric brain tumor consortium report.
    Neuro-oncology, 2014, Volume: 16, Issue:12

    Topics: Adolescent; Adult; Antineoplastic Agents, Alkylating; Benzimidazoles; Brain Neoplasms; Child; Child,

2014
Prognostic and predictive markers in recurrent high grade glioma; results from the BR12 randomised trial.
    Acta neuropathologica communications, 2014, Jun-20, Volume: 2

    Topics: Antineoplastic Agents; Brain Neoplasms; Chromosomes, Human, Pair 1; Chromosomes, Human, Pair 19; Dac

2014
Prognostic and predictive markers in recurrent high grade glioma; results from the BR12 randomised trial.
    Acta neuropathologica communications, 2014, Jun-20, Volume: 2

    Topics: Antineoplastic Agents; Brain Neoplasms; Chromosomes, Human, Pair 1; Chromosomes, Human, Pair 19; Dac

2014
Prognostic and predictive markers in recurrent high grade glioma; results from the BR12 randomised trial.
    Acta neuropathologica communications, 2014, Jun-20, Volume: 2

    Topics: Antineoplastic Agents; Brain Neoplasms; Chromosomes, Human, Pair 1; Chromosomes, Human, Pair 19; Dac

2014
Hypofractionated intensity-modulated radiotherapy with temozolomide chemotherapy may alter the patterns of failure in patients with glioblastoma multiforme.
    Journal of medical imaging and radiation oncology, 2014, Volume: 58, Issue:6

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Dacarbazine; Dos

2014
Hypofractionated intensity-modulated radiotherapy with temozolomide chemotherapy may alter the patterns of failure in patients with glioblastoma multiforme.
    Journal of medical imaging and radiation oncology, 2014, Volume: 58, Issue:6

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Dacarbazine; Dos

2014
Hypofractionated intensity-modulated radiotherapy with temozolomide chemotherapy may alter the patterns of failure in patients with glioblastoma multiforme.
    Journal of medical imaging and radiation oncology, 2014, Volume: 58, Issue:6

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Dacarbazine; Dos

2014
A phase I/II trial of hydroxychloroquine in conjunction with radiation therapy and concurrent and adjuvant temozolomide in patients with newly diagnosed glioblastoma multiforme.
    Autophagy, 2014, Volume: 10, Issue:8

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Autophagy; Brain Neo

2014
A phase I/II trial of hydroxychloroquine in conjunction with radiation therapy and concurrent and adjuvant temozolomide in patients with newly diagnosed glioblastoma multiforme.
    Autophagy, 2014, Volume: 10, Issue:8

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Autophagy; Brain Neo

2014
A phase I/II trial of hydroxychloroquine in conjunction with radiation therapy and concurrent and adjuvant temozolomide in patients with newly diagnosed glioblastoma multiforme.
    Autophagy, 2014, Volume: 10, Issue:8

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Autophagy; Brain Neo

2014
Phase I/IIa trial of fractionated radiotherapy, temozolomide, and autologous formalin-fixed tumor vaccine for newly diagnosed glioblastoma.
    Journal of neurosurgery, 2014, Volume: 121, Issue:3

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cancer Vaccines; Combin

2014
Phase I/IIa trial of fractionated radiotherapy, temozolomide, and autologous formalin-fixed tumor vaccine for newly diagnosed glioblastoma.
    Journal of neurosurgery, 2014, Volume: 121, Issue:3

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cancer Vaccines; Combin

2014
Phase I/IIa trial of fractionated radiotherapy, temozolomide, and autologous formalin-fixed tumor vaccine for newly diagnosed glioblastoma.
    Journal of neurosurgery, 2014, Volume: 121, Issue:3

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cancer Vaccines; Combin

2014
Strategies to prevent brain metastasis in high-risk non-small-cell lung cancer: lessons learned from a randomized study of maintenance temozolomide versus observation.
    Clinical lung cancer, 2014, Volume: 15, Issue:6

    Topics: Aged; Brain; Brain Neoplasms; Carcinoma, Non-Small-Cell Lung; Dacarbazine; Early Termination of Clin

2014
Strategies to prevent brain metastasis in high-risk non-small-cell lung cancer: lessons learned from a randomized study of maintenance temozolomide versus observation.
    Clinical lung cancer, 2014, Volume: 15, Issue:6

    Topics: Aged; Brain; Brain Neoplasms; Carcinoma, Non-Small-Cell Lung; Dacarbazine; Early Termination of Clin

2014
Strategies to prevent brain metastasis in high-risk non-small-cell lung cancer: lessons learned from a randomized study of maintenance temozolomide versus observation.
    Clinical lung cancer, 2014, Volume: 15, Issue:6

    Topics: Aged; Brain; Brain Neoplasms; Carcinoma, Non-Small-Cell Lung; Dacarbazine; Early Termination of Clin

2014
Gene therapy enhances chemotherapy tolerance and efficacy in glioblastoma patients.
    The Journal of clinical investigation, 2014, Volume: 124, Issue:9

    Topics: Adult; Bone Marrow; Brain Neoplasms; Carmustine; Combined Modality Therapy; Dacarbazine; DNA Modific

2014
Gene therapy enhances chemotherapy tolerance and efficacy in glioblastoma patients.
    The Journal of clinical investigation, 2014, Volume: 124, Issue:9

    Topics: Adult; Bone Marrow; Brain Neoplasms; Carmustine; Combined Modality Therapy; Dacarbazine; DNA Modific

2014
Gene therapy enhances chemotherapy tolerance and efficacy in glioblastoma patients.
    The Journal of clinical investigation, 2014, Volume: 124, Issue:9

    Topics: Adult; Bone Marrow; Brain Neoplasms; Carmustine; Combined Modality Therapy; Dacarbazine; DNA Modific

2014
Phase II study of bevacizumab, temozolomide, and hypofractionated stereotactic radiotherapy for newly diagnosed glioblastoma.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2014, Oct-01, Volume: 20, Issue:19

    Topics: Adolescent; Adult; Aged; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Pro

2014
Phase II study of bevacizumab, temozolomide, and hypofractionated stereotactic radiotherapy for newly diagnosed glioblastoma.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2014, Oct-01, Volume: 20, Issue:19

    Topics: Adolescent; Adult; Aged; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Pro

2014
Phase II study of bevacizumab, temozolomide, and hypofractionated stereotactic radiotherapy for newly diagnosed glioblastoma.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2014, Oct-01, Volume: 20, Issue:19

    Topics: Adolescent; Adult; Aged; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Pro

2014
Phase I/randomized phase II study of afatinib, an irreversible ErbB family blocker, with or without protracted temozolomide in adults with recurrent glioblastoma.
    Neuro-oncology, 2015, Volume: 17, Issue:3

    Topics: Adult; Afatinib; Aged; Antineoplastic Agents; Brain Neoplasms; Dacarbazine; Drug Therapy, Combinatio

2015
Phase I/randomized phase II study of afatinib, an irreversible ErbB family blocker, with or without protracted temozolomide in adults with recurrent glioblastoma.
    Neuro-oncology, 2015, Volume: 17, Issue:3

    Topics: Adult; Afatinib; Aged; Antineoplastic Agents; Brain Neoplasms; Dacarbazine; Drug Therapy, Combinatio

2015
Phase I/randomized phase II study of afatinib, an irreversible ErbB family blocker, with or without protracted temozolomide in adults with recurrent glioblastoma.
    Neuro-oncology, 2015, Volume: 17, Issue:3

    Topics: Adult; Afatinib; Aged; Antineoplastic Agents; Brain Neoplasms; Dacarbazine; Drug Therapy, Combinatio

2015
Cilengitide combined with standard treatment for patients with newly diagnosed glioblastoma with methylated MGMT promoter (CENTRIC EORTC 26071-22072 study): a multicentre, randomised, open-label, phase 3 trial.
    The Lancet. Oncology, 2014, Volume: 15, Issue:10

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Confidence Intervals; Dacarba

2014
Cilengitide combined with standard treatment for patients with newly diagnosed glioblastoma with methylated MGMT promoter (CENTRIC EORTC 26071-22072 study): a multicentre, randomised, open-label, phase 3 trial.
    The Lancet. Oncology, 2014, Volume: 15, Issue:10

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Confidence Intervals; Dacarba

2014
Cilengitide combined with standard treatment for patients with newly diagnosed glioblastoma with methylated MGMT promoter (CENTRIC EORTC 26071-22072 study): a multicentre, randomised, open-label, phase 3 trial.
    The Lancet. Oncology, 2014, Volume: 15, Issue:10

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Confidence Intervals; Dacarba

2014
Cilengitide combined with standard treatment for patients with newly diagnosed glioblastoma with methylated MGMT promoter (CENTRIC EORTC 26071-22072 study): a multicentre, randomised, open-label, phase 3 trial.
    The Lancet. Oncology, 2014, Volume: 15, Issue:10

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Confidence Intervals; Dacarba

2014
Cilengitide combined with standard treatment for patients with newly diagnosed glioblastoma with methylated MGMT promoter (CENTRIC EORTC 26071-22072 study): a multicentre, randomised, open-label, phase 3 trial.
    The Lancet. Oncology, 2014, Volume: 15, Issue:10

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Confidence Intervals; Dacarba

2014
Cilengitide combined with standard treatment for patients with newly diagnosed glioblastoma with methylated MGMT promoter (CENTRIC EORTC 26071-22072 study): a multicentre, randomised, open-label, phase 3 trial.
    The Lancet. Oncology, 2014, Volume: 15, Issue:10

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Confidence Intervals; Dacarba

2014
Cilengitide combined with standard treatment for patients with newly diagnosed glioblastoma with methylated MGMT promoter (CENTRIC EORTC 26071-22072 study): a multicentre, randomised, open-label, phase 3 trial.
    The Lancet. Oncology, 2014, Volume: 15, Issue:10

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Confidence Intervals; Dacarba

2014
Cilengitide combined with standard treatment for patients with newly diagnosed glioblastoma with methylated MGMT promoter (CENTRIC EORTC 26071-22072 study): a multicentre, randomised, open-label, phase 3 trial.
    The Lancet. Oncology, 2014, Volume: 15, Issue:10

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Confidence Intervals; Dacarba

2014
Cilengitide combined with standard treatment for patients with newly diagnosed glioblastoma with methylated MGMT promoter (CENTRIC EORTC 26071-22072 study): a multicentre, randomised, open-label, phase 3 trial.
    The Lancet. Oncology, 2014, Volume: 15, Issue:10

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Confidence Intervals; Dacarba

2014
Cilengitide combined with standard treatment for patients with newly diagnosed glioblastoma with methylated MGMT promoter (CENTRIC EORTC 26071-22072 study): a multicentre, randomised, open-label, phase 3 trial.
    The Lancet. Oncology, 2014, Volume: 15, Issue:10

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Confidence Intervals; Dacarba

2014
Cilengitide combined with standard treatment for patients with newly diagnosed glioblastoma with methylated MGMT promoter (CENTRIC EORTC 26071-22072 study): a multicentre, randomised, open-label, phase 3 trial.
    The Lancet. Oncology, 2014, Volume: 15, Issue:10

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Confidence Intervals; Dacarba

2014
Cilengitide combined with standard treatment for patients with newly diagnosed glioblastoma with methylated MGMT promoter (CENTRIC EORTC 26071-22072 study): a multicentre, randomised, open-label, phase 3 trial.
    The Lancet. Oncology, 2014, Volume: 15, Issue:10

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Confidence Intervals; Dacarba

2014
Randomized phase II adjuvant factorial study of dose-dense temozolomide alone and in combination with isotretinoin, celecoxib, and/or thalidomide for glioblastoma.
    Neuro-oncology, 2015, Volume: 17, Issue:2

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cele

2015
Randomized phase II adjuvant factorial study of dose-dense temozolomide alone and in combination with isotretinoin, celecoxib, and/or thalidomide for glioblastoma.
    Neuro-oncology, 2015, Volume: 17, Issue:2

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cele

2015
Randomized phase II adjuvant factorial study of dose-dense temozolomide alone and in combination with isotretinoin, celecoxib, and/or thalidomide for glioblastoma.
    Neuro-oncology, 2015, Volume: 17, Issue:2

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cele

2015
Phase II randomized study of whole-brain radiation therapy with or without concurrent temozolomide for brain metastases from breast cancer.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2015, Volume: 26, Issue:1

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Breast Neoplasms; Combined Modality

2015
Phase II randomized study of whole-brain radiation therapy with or without concurrent temozolomide for brain metastases from breast cancer.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2015, Volume: 26, Issue:1

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Breast Neoplasms; Combined Modality

2015
Phase II randomized study of whole-brain radiation therapy with or without concurrent temozolomide for brain metastases from breast cancer.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2015, Volume: 26, Issue:1

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Breast Neoplasms; Combined Modality

2015
Dendritic cell vaccination combined with temozolomide retreatment: results of a phase I trial in patients with recurrent glioblastoma multiforme.
    Journal of neuro-oncology, 2015, Volume: 121, Issue:2

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain; Brain Neoplasms; Cancer Vaccines; Combined Mo

2015
Dendritic cell vaccination combined with temozolomide retreatment: results of a phase I trial in patients with recurrent glioblastoma multiforme.
    Journal of neuro-oncology, 2015, Volume: 121, Issue:2

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain; Brain Neoplasms; Cancer Vaccines; Combined Mo

2015
Dendritic cell vaccination combined with temozolomide retreatment: results of a phase I trial in patients with recurrent glioblastoma multiforme.
    Journal of neuro-oncology, 2015, Volume: 121, Issue:2

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain; Brain Neoplasms; Cancer Vaccines; Combined Mo

2015
Phase II trial of hypofractionated intensity-modulated radiation therapy combined with temozolomide and bevacizumab for patients with newly diagnosed glioblastoma.
    Journal of neuro-oncology, 2015, Volume: 122, Issue:1

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Brain Neoplasms; Chemoradi

2015
Phase II trial of hypofractionated intensity-modulated radiation therapy combined with temozolomide and bevacizumab for patients with newly diagnosed glioblastoma.
    Journal of neuro-oncology, 2015, Volume: 122, Issue:1

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Brain Neoplasms; Chemoradi

2015
Phase II trial of hypofractionated intensity-modulated radiation therapy combined with temozolomide and bevacizumab for patients with newly diagnosed glioblastoma.
    Journal of neuro-oncology, 2015, Volume: 122, Issue:1

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Brain Neoplasms; Chemoradi

2015
A phase II trial of everolimus, temozolomide, and radiotherapy in patients with newly diagnosed glioblastoma: NCCTG N057K.
    Neuro-oncology, 2015, Volume: 17, Issue:9

    Topics: Antineoplastic Agents; Brain Neoplasms; Dacarbazine; Drug Therapy, Combination; Everolimus; Glioblas

2015
A phase II trial of everolimus, temozolomide, and radiotherapy in patients with newly diagnosed glioblastoma: NCCTG N057K.
    Neuro-oncology, 2015, Volume: 17, Issue:9

    Topics: Antineoplastic Agents; Brain Neoplasms; Dacarbazine; Drug Therapy, Combination; Everolimus; Glioblas

2015
A phase II trial of everolimus, temozolomide, and radiotherapy in patients with newly diagnosed glioblastoma: NCCTG N057K.
    Neuro-oncology, 2015, Volume: 17, Issue:9

    Topics: Antineoplastic Agents; Brain Neoplasms; Dacarbazine; Drug Therapy, Combination; Everolimus; Glioblas

2015
Efficacy and patient-reported outcomes with dose-intense temozolomide in patients with newly diagnosed pure and mixed anaplastic oligodendroglioma: a phase II multicenter study.
    Journal of neuro-oncology, 2015, Volume: 122, Issue:1

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chro

2015
Efficacy and patient-reported outcomes with dose-intense temozolomide in patients with newly diagnosed pure and mixed anaplastic oligodendroglioma: a phase II multicenter study.
    Journal of neuro-oncology, 2015, Volume: 122, Issue:1

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chro

2015
Efficacy and patient-reported outcomes with dose-intense temozolomide in patients with newly diagnosed pure and mixed anaplastic oligodendroglioma: a phase II multicenter study.
    Journal of neuro-oncology, 2015, Volume: 122, Issue:1

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chro

2015
Bevacizumab in combination with radiotherapy and temozolomide for patients with newly diagnosed glioblastoma multiforme.
    The oncologist, 2015, Volume: 20, Issue:2

    Topics: Adult; Aged; Bevacizumab; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease-Free Surv

2015
Bevacizumab in combination with radiotherapy and temozolomide for patients with newly diagnosed glioblastoma multiforme.
    The oncologist, 2015, Volume: 20, Issue:2

    Topics: Adult; Aged; Bevacizumab; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease-Free Surv

2015
Bevacizumab in combination with radiotherapy and temozolomide for patients with newly diagnosed glioblastoma multiforme.
    The oncologist, 2015, Volume: 20, Issue:2

    Topics: Adult; Aged; Bevacizumab; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease-Free Surv

2015
A phase II, multicenter trial of rindopepimut (CDX-110) in newly diagnosed glioblastoma: the ACT III study.
    Neuro-oncology, 2015, Volume: 17, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Brain Neoplasms; Cancer Vaccines; Chemoradiot

2015
A phase II, multicenter trial of rindopepimut (CDX-110) in newly diagnosed glioblastoma: the ACT III study.
    Neuro-oncology, 2015, Volume: 17, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Brain Neoplasms; Cancer Vaccines; Chemoradiot

2015
A phase II, multicenter trial of rindopepimut (CDX-110) in newly diagnosed glioblastoma: the ACT III study.
    Neuro-oncology, 2015, Volume: 17, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Brain Neoplasms; Cancer Vaccines; Chemoradiot

2015
Dynamic susceptibility contrast MRI measures of relative cerebral blood volume as a prognostic marker for overall survival in recurrent glioblastoma: results from the ACRIN 6677/RTOG 0625 multicenter trial.
    Neuro-oncology, 2015, Volume: 17, Issue:8

    Topics: Adult; Aged; Angiogenesis Inhibitors; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Phyt

2015
Dynamic susceptibility contrast MRI measures of relative cerebral blood volume as a prognostic marker for overall survival in recurrent glioblastoma: results from the ACRIN 6677/RTOG 0625 multicenter trial.
    Neuro-oncology, 2015, Volume: 17, Issue:8

    Topics: Adult; Aged; Angiogenesis Inhibitors; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Phyt

2015
Dynamic susceptibility contrast MRI measures of relative cerebral blood volume as a prognostic marker for overall survival in recurrent glioblastoma: results from the ACRIN 6677/RTOG 0625 multicenter trial.
    Neuro-oncology, 2015, Volume: 17, Issue:8

    Topics: Adult; Aged; Angiogenesis Inhibitors; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Phyt

2015
MGMT Promoter Methylation Is a Strong Prognostic Biomarker for Benefit from Dose-Intensified Temozolomide Rechallenge in Progressive Glioblastoma: The DIRECTOR Trial.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2015, May-01, Volume: 21, Issue:9

    Topics: Adult; Antineoplastic Agents, Alkylating; Biomarkers, Tumor; Brain Neoplasms; Dacarbazine; Disease-F

2015
MGMT Promoter Methylation Is a Strong Prognostic Biomarker for Benefit from Dose-Intensified Temozolomide Rechallenge in Progressive Glioblastoma: The DIRECTOR Trial.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2015, May-01, Volume: 21, Issue:9

    Topics: Adult; Antineoplastic Agents, Alkylating; Biomarkers, Tumor; Brain Neoplasms; Dacarbazine; Disease-F

2015
MGMT Promoter Methylation Is a Strong Prognostic Biomarker for Benefit from Dose-Intensified Temozolomide Rechallenge in Progressive Glioblastoma: The DIRECTOR Trial.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2015, May-01, Volume: 21, Issue:9

    Topics: Adult; Antineoplastic Agents, Alkylating; Biomarkers, Tumor; Brain Neoplasms; Dacarbazine; Disease-F

2015
Phase 2 study of temozolomide-based chemoradiation therapy for high-risk low-grade gliomas: preliminary results of Radiation Therapy Oncology Group 0424.
    International journal of radiation oncology, biology, physics, 2015, Mar-01, Volume: 91, Issue:3

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Dacarbazine; Dis

2015
Phase 2 study of temozolomide-based chemoradiation therapy for high-risk low-grade gliomas: preliminary results of Radiation Therapy Oncology Group 0424.
    International journal of radiation oncology, biology, physics, 2015, Mar-01, Volume: 91, Issue:3

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Dacarbazine; Dis

2015
Phase 2 study of temozolomide-based chemoradiation therapy for high-risk low-grade gliomas: preliminary results of Radiation Therapy Oncology Group 0424.
    International journal of radiation oncology, biology, physics, 2015, Mar-01, Volume: 91, Issue:3

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Dacarbazine; Dis

2015
Variation over time and interdependence between disease progression and death among patients with glioblastoma on RTOG 0525.
    Neuro-oncology, 2015, Volume: 17, Issue:7

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Disease Progression; DNA Methylatio

2015
Variation over time and interdependence between disease progression and death among patients with glioblastoma on RTOG 0525.
    Neuro-oncology, 2015, Volume: 17, Issue:7

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Disease Progression; DNA Methylatio

2015
Variation over time and interdependence between disease progression and death among patients with glioblastoma on RTOG 0525.
    Neuro-oncology, 2015, Volume: 17, Issue:7

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Disease Progression; DNA Methylatio

2015
Two cilengitide regimens in combination with standard treatment for patients with newly diagnosed glioblastoma and unmethylated MGMT gene promoter: results of the open-label, controlled, randomized phase II CORE study.
    Neuro-oncology, 2015, Volume: 17, Issue:5

    Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms;

2015
Two cilengitide regimens in combination with standard treatment for patients with newly diagnosed glioblastoma and unmethylated MGMT gene promoter: results of the open-label, controlled, randomized phase II CORE study.
    Neuro-oncology, 2015, Volume: 17, Issue:5

    Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms;

2015
Two cilengitide regimens in combination with standard treatment for patients with newly diagnosed glioblastoma and unmethylated MGMT gene promoter: results of the open-label, controlled, randomized phase II CORE study.
    Neuro-oncology, 2015, Volume: 17, Issue:5

    Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms;

2015
Wilms tumor 1 peptide vaccination combined with temozolomide against newly diagnosed glioblastoma: safety and impact on immunological response.
    Cancer immunology, immunotherapy : CII, 2015, Volume: 64, Issue:6

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Cancer Vaccines; Cohort Stud

2015
Wilms tumor 1 peptide vaccination combined with temozolomide against newly diagnosed glioblastoma: safety and impact on immunological response.
    Cancer immunology, immunotherapy : CII, 2015, Volume: 64, Issue:6

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Cancer Vaccines; Cohort Stud

2015
Wilms tumor 1 peptide vaccination combined with temozolomide against newly diagnosed glioblastoma: safety and impact on immunological response.
    Cancer immunology, immunotherapy : CII, 2015, Volume: 64, Issue:6

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Cancer Vaccines; Cohort Stud

2015
Phase 1/2 trials of Temozolomide, Motexafin Gadolinium, and 60-Gy fractionated radiation for newly diagnosed supratentorial glioblastoma multiforme: final results of RTOG 0513.
    International journal of radiation oncology, biology, physics, 2015, Apr-01, Volume: 91, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms;

2015
Phase 1/2 trials of Temozolomide, Motexafin Gadolinium, and 60-Gy fractionated radiation for newly diagnosed supratentorial glioblastoma multiforme: final results of RTOG 0513.
    International journal of radiation oncology, biology, physics, 2015, Apr-01, Volume: 91, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms;

2015
Phase 1/2 trials of Temozolomide, Motexafin Gadolinium, and 60-Gy fractionated radiation for newly diagnosed supratentorial glioblastoma multiforme: final results of RTOG 0513.
    International journal of radiation oncology, biology, physics, 2015, Apr-01, Volume: 91, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms;

2015
Phase 1/2 trials of Temozolomide, Motexafin Gadolinium, and 60-Gy fractionated radiation for newly diagnosed supratentorial glioblastoma multiforme: final results of RTOG 0513.
    International journal of radiation oncology, biology, physics, 2015, Apr-01, Volume: 91, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms;

2015
Phase 1/2 trials of Temozolomide, Motexafin Gadolinium, and 60-Gy fractionated radiation for newly diagnosed supratentorial glioblastoma multiforme: final results of RTOG 0513.
    International journal of radiation oncology, biology, physics, 2015, Apr-01, Volume: 91, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms;

2015
Phase 1/2 trials of Temozolomide, Motexafin Gadolinium, and 60-Gy fractionated radiation for newly diagnosed supratentorial glioblastoma multiforme: final results of RTOG 0513.
    International journal of radiation oncology, biology, physics, 2015, Apr-01, Volume: 91, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms;

2015
Phase 1/2 trials of Temozolomide, Motexafin Gadolinium, and 60-Gy fractionated radiation for newly diagnosed supratentorial glioblastoma multiforme: final results of RTOG 0513.
    International journal of radiation oncology, biology, physics, 2015, Apr-01, Volume: 91, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms;

2015
Phase 1/2 trials of Temozolomide, Motexafin Gadolinium, and 60-Gy fractionated radiation for newly diagnosed supratentorial glioblastoma multiforme: final results of RTOG 0513.
    International journal of radiation oncology, biology, physics, 2015, Apr-01, Volume: 91, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms;

2015
Phase 1/2 trials of Temozolomide, Motexafin Gadolinium, and 60-Gy fractionated radiation for newly diagnosed supratentorial glioblastoma multiforme: final results of RTOG 0513.
    International journal of radiation oncology, biology, physics, 2015, Apr-01, Volume: 91, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms;

2015
Phase 1/2 trials of Temozolomide, Motexafin Gadolinium, and 60-Gy fractionated radiation for newly diagnosed supratentorial glioblastoma multiforme: final results of RTOG 0513.
    International journal of radiation oncology, biology, physics, 2015, Apr-01, Volume: 91, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms;

2015
Phase 1/2 trials of Temozolomide, Motexafin Gadolinium, and 60-Gy fractionated radiation for newly diagnosed supratentorial glioblastoma multiforme: final results of RTOG 0513.
    International journal of radiation oncology, biology, physics, 2015, Apr-01, Volume: 91, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms;

2015
Phase 1/2 trials of Temozolomide, Motexafin Gadolinium, and 60-Gy fractionated radiation for newly diagnosed supratentorial glioblastoma multiforme: final results of RTOG 0513.
    International journal of radiation oncology, biology, physics, 2015, Apr-01, Volume: 91, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms;

2015
Hypofractionated-intensity modulated radiotherapy (hypo-IMRT) and temozolomide (TMZ) with or without bevacizumab (BEV) for newly diagnosed glioblastoma multiforme (GBM): a comparison of two prospective phase II trials.
    Journal of neuro-oncology, 2015, Volume: 123, Issue:2

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Brain Neoplasms; Chemoradi

2015
Hypofractionated-intensity modulated radiotherapy (hypo-IMRT) and temozolomide (TMZ) with or without bevacizumab (BEV) for newly diagnosed glioblastoma multiforme (GBM): a comparison of two prospective phase II trials.
    Journal of neuro-oncology, 2015, Volume: 123, Issue:2

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Brain Neoplasms; Chemoradi

2015
Hypofractionated-intensity modulated radiotherapy (hypo-IMRT) and temozolomide (TMZ) with or without bevacizumab (BEV) for newly diagnosed glioblastoma multiforme (GBM): a comparison of two prospective phase II trials.
    Journal of neuro-oncology, 2015, Volume: 123, Issue:2

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Brain Neoplasms; Chemoradi

2015
Comparison of radiation regimens in the treatment of Glioblastoma multiforme: results from a single institution.
    Radiation oncology (London, England), 2015, Apr-26, Volume: 10

    Topics: Aged; Antineoplastic Agents, Alkylating; Brachytherapy; Brain Neoplasms; Chemoradiotherapy; Dacarbaz

2015
Comparison of radiation regimens in the treatment of Glioblastoma multiforme: results from a single institution.
    Radiation oncology (London, England), 2015, Apr-26, Volume: 10

    Topics: Aged; Antineoplastic Agents, Alkylating; Brachytherapy; Brain Neoplasms; Chemoradiotherapy; Dacarbaz

2015
Comparison of radiation regimens in the treatment of Glioblastoma multiforme: results from a single institution.
    Radiation oncology (London, England), 2015, Apr-26, Volume: 10

    Topics: Aged; Antineoplastic Agents, Alkylating; Brachytherapy; Brain Neoplasms; Chemoradiotherapy; Dacarbaz

2015
BCNU wafer placement with temozolomide (TMZ) in the immediate postoperative period after tumor resection followed by radiation therapy with TMZ in patients with newly diagnosed high grade glioma: final results of a prospective, multi-institutional, phase
    Journal of neuro-oncology, 2015, Volume: 123, Issue:2

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carmustine; Combined M

2015
BCNU wafer placement with temozolomide (TMZ) in the immediate postoperative period after tumor resection followed by radiation therapy with TMZ in patients with newly diagnosed high grade glioma: final results of a prospective, multi-institutional, phase
    Journal of neuro-oncology, 2015, Volume: 123, Issue:2

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carmustine; Combined M

2015
BCNU wafer placement with temozolomide (TMZ) in the immediate postoperative period after tumor resection followed by radiation therapy with TMZ in patients with newly diagnosed high grade glioma: final results of a prospective, multi-institutional, phase
    Journal of neuro-oncology, 2015, Volume: 123, Issue:2

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carmustine; Combined M

2015
Health-Related Quality of Life in a Randomized Phase III Study of Bevacizumab, Temozolomide, and Radiotherapy in Newly Diagnosed Glioblastoma.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2015, Jul-01, Volume: 33, Issue:19

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humaniz

2015
Health-Related Quality of Life in a Randomized Phase III Study of Bevacizumab, Temozolomide, and Radiotherapy in Newly Diagnosed Glioblastoma.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2015, Jul-01, Volume: 33, Issue:19

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humaniz

2015
Health-Related Quality of Life in a Randomized Phase III Study of Bevacizumab, Temozolomide, and Radiotherapy in Newly Diagnosed Glioblastoma.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2015, Jul-01, Volume: 33, Issue:19

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humaniz

2015
Health-Related Quality of Life in a Randomized Phase III Study of Bevacizumab, Temozolomide, and Radiotherapy in Newly Diagnosed Glioblastoma.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2015, Jul-01, Volume: 33, Issue:19

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humaniz

2015
Health-Related Quality of Life in a Randomized Phase III Study of Bevacizumab, Temozolomide, and Radiotherapy in Newly Diagnosed Glioblastoma.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2015, Jul-01, Volume: 33, Issue:19

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humaniz

2015
Health-Related Quality of Life in a Randomized Phase III Study of Bevacizumab, Temozolomide, and Radiotherapy in Newly Diagnosed Glioblastoma.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2015, Jul-01, Volume: 33, Issue:19

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humaniz

2015
Health-Related Quality of Life in a Randomized Phase III Study of Bevacizumab, Temozolomide, and Radiotherapy in Newly Diagnosed Glioblastoma.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2015, Jul-01, Volume: 33, Issue:19

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humaniz

2015
Health-Related Quality of Life in a Randomized Phase III Study of Bevacizumab, Temozolomide, and Radiotherapy in Newly Diagnosed Glioblastoma.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2015, Jul-01, Volume: 33, Issue:19

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humaniz

2015
Health-Related Quality of Life in a Randomized Phase III Study of Bevacizumab, Temozolomide, and Radiotherapy in Newly Diagnosed Glioblastoma.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2015, Jul-01, Volume: 33, Issue:19

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humaniz

2015
Health-Related Quality of Life in a Randomized Phase III Study of Bevacizumab, Temozolomide, and Radiotherapy in Newly Diagnosed Glioblastoma.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2015, Jul-01, Volume: 33, Issue:19

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humaniz

2015
Health-Related Quality of Life in a Randomized Phase III Study of Bevacizumab, Temozolomide, and Radiotherapy in Newly Diagnosed Glioblastoma.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2015, Jul-01, Volume: 33, Issue:19

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humaniz

2015
Health-Related Quality of Life in a Randomized Phase III Study of Bevacizumab, Temozolomide, and Radiotherapy in Newly Diagnosed Glioblastoma.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2015, Jul-01, Volume: 33, Issue:19

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humaniz

2015
Phase I dose-escalation study of the PI3K/mTOR inhibitor voxtalisib (SAR245409, XL765) plus temozolomide with or without radiotherapy in patients with high-grade glioma.
    Neuro-oncology, 2015, Volume: 17, Issue:9

    Topics: Administration, Oral; Adult; Aged; Antineoplastic Agents; Brain Neoplasms; Dacarbazine; Dose-Respons

2015
Phase I dose-escalation study of the PI3K/mTOR inhibitor voxtalisib (SAR245409, XL765) plus temozolomide with or without radiotherapy in patients with high-grade glioma.
    Neuro-oncology, 2015, Volume: 17, Issue:9

    Topics: Administration, Oral; Adult; Aged; Antineoplastic Agents; Brain Neoplasms; Dacarbazine; Dose-Respons

2015
Phase I dose-escalation study of the PI3K/mTOR inhibitor voxtalisib (SAR245409, XL765) plus temozolomide with or without radiotherapy in patients with high-grade glioma.
    Neuro-oncology, 2015, Volume: 17, Issue:9

    Topics: Administration, Oral; Adult; Aged; Antineoplastic Agents; Brain Neoplasms; Dacarbazine; Dose-Respons

2015
Phase II Trial of Upfront Bevacizumab, Irinotecan, and Temozolomide for Unresectable Glioblastoma.
    The oncologist, 2015, Volume: 20, Issue:7

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Brain Neoplasms; Camptothecin; Dacarbaz

2015
Phase II Trial of Upfront Bevacizumab, Irinotecan, and Temozolomide for Unresectable Glioblastoma.
    The oncologist, 2015, Volume: 20, Issue:7

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Brain Neoplasms; Camptothecin; Dacarbaz

2015
Phase II Trial of Upfront Bevacizumab, Irinotecan, and Temozolomide for Unresectable Glioblastoma.
    The oncologist, 2015, Volume: 20, Issue:7

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Brain Neoplasms; Camptothecin; Dacarbaz

2015
A phase II study of feasibility and toxicity of bevacizumab in combination with temozolomide in patients with recurrent glioblastoma.
    Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico, 2015, Volume: 17, Issue:9

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Brain Neoplasms; Dacarbazi

2015
A phase II study of feasibility and toxicity of bevacizumab in combination with temozolomide in patients with recurrent glioblastoma.
    Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico, 2015, Volume: 17, Issue:9

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Brain Neoplasms; Dacarbazi

2015
A phase II study of feasibility and toxicity of bevacizumab in combination with temozolomide in patients with recurrent glioblastoma.
    Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico, 2015, Volume: 17, Issue:9

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Brain Neoplasms; Dacarbazi

2015
Phase II trial of pre-irradiation and concurrent temozolomide in patients with newly diagnosed anaplastic oligodendrogliomas and mixed anaplastic oligoastrocytomas: long term results of RTOG BR0131.
    Journal of neuro-oncology, 2015, Volume: 124, Issue:3

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Female; Hu

2015
Phase II trial of pre-irradiation and concurrent temozolomide in patients with newly diagnosed anaplastic oligodendrogliomas and mixed anaplastic oligoastrocytomas: long term results of RTOG BR0131.
    Journal of neuro-oncology, 2015, Volume: 124, Issue:3

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Female; Hu

2015
Phase II trial of pre-irradiation and concurrent temozolomide in patients with newly diagnosed anaplastic oligodendrogliomas and mixed anaplastic oligoastrocytomas: long term results of RTOG BR0131.
    Journal of neuro-oncology, 2015, Volume: 124, Issue:3

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Female; Hu

2015
A Phase 2 Study of Concurrent Radiation Therapy, Temozolomide, and the Histone Deacetylase Inhibitor Valproic Acid for Patients With Glioblastoma.
    International journal of radiation oncology, biology, physics, 2015, Aug-01, Volume: 92, Issue:5

    Topics: Adult; Age Factors; Aged; Antineoplastic Agents, Alkylating; Bone Marrow; Brain Neoplasms; Chemoradi

2015
A Phase 2 Study of Concurrent Radiation Therapy, Temozolomide, and the Histone Deacetylase Inhibitor Valproic Acid for Patients With Glioblastoma.
    International journal of radiation oncology, biology, physics, 2015, Aug-01, Volume: 92, Issue:5

    Topics: Adult; Age Factors; Aged; Antineoplastic Agents, Alkylating; Bone Marrow; Brain Neoplasms; Chemoradi

2015
A Phase 2 Study of Concurrent Radiation Therapy, Temozolomide, and the Histone Deacetylase Inhibitor Valproic Acid for Patients With Glioblastoma.
    International journal of radiation oncology, biology, physics, 2015, Aug-01, Volume: 92, Issue:5

    Topics: Adult; Age Factors; Aged; Antineoplastic Agents, Alkylating; Bone Marrow; Brain Neoplasms; Chemoradi

2015
Randomized phase II study evaluating veliparib (ABT-888) with temozolomide in patients with metastatic melanoma.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2015, Volume: 26, Issue:10

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Benzimidazoles; Brain Neoplasms;

2015
Randomized phase II study evaluating veliparib (ABT-888) with temozolomide in patients with metastatic melanoma.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2015, Volume: 26, Issue:10

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Benzimidazoles; Brain Neoplasms;

2015
Randomized phase II study evaluating veliparib (ABT-888) with temozolomide in patients with metastatic melanoma.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2015, Volume: 26, Issue:10

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Benzimidazoles; Brain Neoplasms;

2015
Randomized phase II study evaluating veliparib (ABT-888) with temozolomide in patients with metastatic melanoma.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2015, Volume: 26, Issue:10

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Benzimidazoles; Brain Neoplasms;

2015
Randomized phase II study evaluating veliparib (ABT-888) with temozolomide in patients with metastatic melanoma.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2015, Volume: 26, Issue:10

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Benzimidazoles; Brain Neoplasms;

2015
Randomized phase II study evaluating veliparib (ABT-888) with temozolomide in patients with metastatic melanoma.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2015, Volume: 26, Issue:10

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Benzimidazoles; Brain Neoplasms;

2015
Randomized phase II study evaluating veliparib (ABT-888) with temozolomide in patients with metastatic melanoma.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2015, Volume: 26, Issue:10

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Benzimidazoles; Brain Neoplasms;

2015
Randomized phase II study evaluating veliparib (ABT-888) with temozolomide in patients with metastatic melanoma.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2015, Volume: 26, Issue:10

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Benzimidazoles; Brain Neoplasms;

2015
Randomized phase II study evaluating veliparib (ABT-888) with temozolomide in patients with metastatic melanoma.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2015, Volume: 26, Issue:10

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Benzimidazoles; Brain Neoplasms;

2015
Randomized phase II study evaluating veliparib (ABT-888) with temozolomide in patients with metastatic melanoma.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2015, Volume: 26, Issue:10

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Benzimidazoles; Brain Neoplasms;

2015
Randomized phase II study evaluating veliparib (ABT-888) with temozolomide in patients with metastatic melanoma.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2015, Volume: 26, Issue:10

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Benzimidazoles; Brain Neoplasms;

2015
Randomized phase II study evaluating veliparib (ABT-888) with temozolomide in patients with metastatic melanoma.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2015, Volume: 26, Issue:10

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Benzimidazoles; Brain Neoplasms;

2015
Standard chemoradiation for glioblastoma results in progressive brain volume loss.
    Neurology, 2015, Aug-25, Volume: 85, Issue:8

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Antineoplastic Protocols; Brain; Brain Neoplasms; Ch

2015
Standard chemoradiation for glioblastoma results in progressive brain volume loss.
    Neurology, 2015, Aug-25, Volume: 85, Issue:8

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Antineoplastic Protocols; Brain; Brain Neoplasms; Ch

2015
Standard chemoradiation for glioblastoma results in progressive brain volume loss.
    Neurology, 2015, Aug-25, Volume: 85, Issue:8

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Antineoplastic Protocols; Brain; Brain Neoplasms; Ch

2015
Phase I study of iniparib concurrent with monthly or continuous temozolomide dosing schedules in patients with newly diagnosed malignant gliomas.
    Journal of neuro-oncology, 2015, Volume: 125, Issue:1

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Benz

2015
Phase I study of iniparib concurrent with monthly or continuous temozolomide dosing schedules in patients with newly diagnosed malignant gliomas.
    Journal of neuro-oncology, 2015, Volume: 125, Issue:1

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Benz

2015
Phase I study of iniparib concurrent with monthly or continuous temozolomide dosing schedules in patients with newly diagnosed malignant gliomas.
    Journal of neuro-oncology, 2015, Volume: 125, Issue:1

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Benz

2015
Sunitinib Malate plus Lomustine for Patients with Temozolomide-refractory Recurrent Anaplastic or Low-grade Glioma.
    Anticancer research, 2015, Volume: 35, Issue:10

    Topics: Adult; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Brain Neop

2015
Sunitinib Malate plus Lomustine for Patients with Temozolomide-refractory Recurrent Anaplastic or Low-grade Glioma.
    Anticancer research, 2015, Volume: 35, Issue:10

    Topics: Adult; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Brain Neop

2015
Sunitinib Malate plus Lomustine for Patients with Temozolomide-refractory Recurrent Anaplastic or Low-grade Glioma.
    Anticancer research, 2015, Volume: 35, Issue:10

    Topics: Adult; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Brain Neop

2015
The Diagnostic Ability of Follow-Up Imaging Biomarkers after Treatment of Glioblastoma in the Temozolomide Era: Implications from Proton MR Spectroscopy and Apparent Diffusion Coefficient Mapping.
    BioMed research international, 2015, Volume: 2015

    Topics: Biomarkers, Tumor; Brain Neoplasms; Chemoradiotherapy; Dacarbazine; Diffusion Tensor Imaging; Female

2015
The Diagnostic Ability of Follow-Up Imaging Biomarkers after Treatment of Glioblastoma in the Temozolomide Era: Implications from Proton MR Spectroscopy and Apparent Diffusion Coefficient Mapping.
    BioMed research international, 2015, Volume: 2015

    Topics: Biomarkers, Tumor; Brain Neoplasms; Chemoradiotherapy; Dacarbazine; Diffusion Tensor Imaging; Female

2015
The Diagnostic Ability of Follow-Up Imaging Biomarkers after Treatment of Glioblastoma in the Temozolomide Era: Implications from Proton MR Spectroscopy and Apparent Diffusion Coefficient Mapping.
    BioMed research international, 2015, Volume: 2015

    Topics: Biomarkers, Tumor; Brain Neoplasms; Chemoradiotherapy; Dacarbazine; Diffusion Tensor Imaging; Female

2015
A phase II study of bevacizumab and erlotinib after radiation and temozolomide in MGMT unmethylated GBM patients.
    Journal of neuro-oncology, 2016, Volume: 126, Issue:1

    Topics: Adult; Antineoplastic Agents; Bevacizumab; Brain Neoplasms; Dacarbazine; Disease-Free Survival; DNA

2016
A phase II study of bevacizumab and erlotinib after radiation and temozolomide in MGMT unmethylated GBM patients.
    Journal of neuro-oncology, 2016, Volume: 126, Issue:1

    Topics: Adult; Antineoplastic Agents; Bevacizumab; Brain Neoplasms; Dacarbazine; Disease-Free Survival; DNA

2016
A phase II study of bevacizumab and erlotinib after radiation and temozolomide in MGMT unmethylated GBM patients.
    Journal of neuro-oncology, 2016, Volume: 126, Issue:1

    Topics: Adult; Antineoplastic Agents; Bevacizumab; Brain Neoplasms; Dacarbazine; Disease-Free Survival; DNA

2016
A concurrent ultra-fractionated radiation therapy and temozolomide treatment: A promising therapy for newly diagnosed, inoperable glioblastoma.
    International journal of cancer, 2016, Mar-15, Volume: 138, Issue:6

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Dacarbazine; DNA

2016
A concurrent ultra-fractionated radiation therapy and temozolomide treatment: A promising therapy for newly diagnosed, inoperable glioblastoma.
    International journal of cancer, 2016, Mar-15, Volume: 138, Issue:6

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Dacarbazine; DNA

2016
A concurrent ultra-fractionated radiation therapy and temozolomide treatment: A promising therapy for newly diagnosed, inoperable glioblastoma.
    International journal of cancer, 2016, Mar-15, Volume: 138, Issue:6

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Dacarbazine; DNA

2016
A randomized phase I/II study of ABT-888 in combination with temozolomide in recurrent temozolomide resistant glioblastoma: an NRG oncology RTOG group study.
    Journal of neuro-oncology, 2016, Volume: 126, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Benzimidazoles; Bevacizumab; Brai

2016
A randomized phase I/II study of ABT-888 in combination with temozolomide in recurrent temozolomide resistant glioblastoma: an NRG oncology RTOG group study.
    Journal of neuro-oncology, 2016, Volume: 126, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Benzimidazoles; Bevacizumab; Brai

2016
A randomized phase I/II study of ABT-888 in combination with temozolomide in recurrent temozolomide resistant glioblastoma: an NRG oncology RTOG group study.
    Journal of neuro-oncology, 2016, Volume: 126, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Benzimidazoles; Bevacizumab; Brai

2016
Phase II trial of irinotecan and metronomic temozolomide in patients with recurrent glioblastoma.
    Anti-cancer drugs, 2016, Volume: 27, Issue:2

    Topics: Administration, Metronomic; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neopl

2016
Phase II trial of irinotecan and metronomic temozolomide in patients with recurrent glioblastoma.
    Anti-cancer drugs, 2016, Volume: 27, Issue:2

    Topics: Administration, Metronomic; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neopl

2016
Phase II trial of irinotecan and metronomic temozolomide in patients with recurrent glioblastoma.
    Anti-cancer drugs, 2016, Volume: 27, Issue:2

    Topics: Administration, Metronomic; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neopl

2016
Phase 1 dose escalation trial of the safety and pharmacokinetics of cabozantinib concurrent with temozolomide and radiotherapy or temozolomide after radiotherapy in newly diagnosed patients with high-grade gliomas.
    Cancer, 2016, Feb-15, Volume: 122, Issue:4

    Topics: Adult; Aged; Alanine Transaminase; Anilides; Antineoplastic Combined Chemotherapy Protocols; Asparta

2016
Phase 1 dose escalation trial of the safety and pharmacokinetics of cabozantinib concurrent with temozolomide and radiotherapy or temozolomide after radiotherapy in newly diagnosed patients with high-grade gliomas.
    Cancer, 2016, Feb-15, Volume: 122, Issue:4

    Topics: Adult; Aged; Alanine Transaminase; Anilides; Antineoplastic Combined Chemotherapy Protocols; Asparta

2016
Phase 1 dose escalation trial of the safety and pharmacokinetics of cabozantinib concurrent with temozolomide and radiotherapy or temozolomide after radiotherapy in newly diagnosed patients with high-grade gliomas.
    Cancer, 2016, Feb-15, Volume: 122, Issue:4

    Topics: Adult; Aged; Alanine Transaminase; Anilides; Antineoplastic Combined Chemotherapy Protocols; Asparta

2016
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
    JAMA, 2015, Dec-15, Volume: 314, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Carmusti

2015
[Randomized controlled study of limited margins IMRT and temozolomide chemotherapy in patients with malignant glioma].
    Zhonghua yi xue za zhi, 2015, Aug-18, Volume: 95, Issue:31

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Chemotherapy, Adjuvant; Dacar

2015
[Randomized controlled study of limited margins IMRT and temozolomide chemotherapy in patients with malignant glioma].
    Zhonghua yi xue za zhi, 2015, Aug-18, Volume: 95, Issue:31

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Chemotherapy, Adjuvant; Dacar

2015
[Randomized controlled study of limited margins IMRT and temozolomide chemotherapy in patients with malignant glioma].
    Zhonghua yi xue za zhi, 2015, Aug-18, Volume: 95, Issue:31

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Chemotherapy, Adjuvant; Dacar

2015
Phase I study of temozolomide in combination with thiotepa and carboplatin with autologous hematopoietic cell rescue in patients with malignant brain tumors with minimal residual disease.
    Bone marrow transplantation, 2016, Volume: 51, Issue:4

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Autografts; Brain Neoplasms; Carb

2016
Phase I study of temozolomide in combination with thiotepa and carboplatin with autologous hematopoietic cell rescue in patients with malignant brain tumors with minimal residual disease.
    Bone marrow transplantation, 2016, Volume: 51, Issue:4

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Autografts; Brain Neoplasms; Carb

2016
Phase I study of temozolomide in combination with thiotepa and carboplatin with autologous hematopoietic cell rescue in patients with malignant brain tumors with minimal residual disease.
    Bone marrow transplantation, 2016, Volume: 51, Issue:4

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Autografts; Brain Neoplasms; Carb

2016
The role of temozolomide in the management of patients with newly diagnosed anaplastic astrocytoma: a comparison of survival in the era prior to and following the availability of temozolomide.
    Journal of neuro-oncology, 2016, Volume: 127, Issue:1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Astrocytoma; Brain Neoplasms; Carmustine; Dacarbazin

2016
The role of temozolomide in the management of patients with newly diagnosed anaplastic astrocytoma: a comparison of survival in the era prior to and following the availability of temozolomide.
    Journal of neuro-oncology, 2016, Volume: 127, Issue:1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Astrocytoma; Brain Neoplasms; Carmustine; Dacarbazin

2016
The role of temozolomide in the management of patients with newly diagnosed anaplastic astrocytoma: a comparison of survival in the era prior to and following the availability of temozolomide.
    Journal of neuro-oncology, 2016, Volume: 127, Issue:1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Astrocytoma; Brain Neoplasms; Carmustine; Dacarbazin

2016
Bevacizumab, temozolomide, and radiotherapy for newly diagnosed glioblastoma: comprehensive safety results during and after first-line therapy.
    Neuro-oncology, 2016, Volume: 18, Issue:7

    Topics: Adult; Aged; Aged, 80 and over; Antibodies, Monoclonal, Humanized; Bevacizumab; Brain Neoplasms; Che

2016
Bevacizumab, temozolomide, and radiotherapy for newly diagnosed glioblastoma: comprehensive safety results during and after first-line therapy.
    Neuro-oncology, 2016, Volume: 18, Issue:7

    Topics: Adult; Aged; Aged, 80 and over; Antibodies, Monoclonal, Humanized; Bevacizumab; Brain Neoplasms; Che

2016
Bevacizumab, temozolomide, and radiotherapy for newly diagnosed glioblastoma: comprehensive safety results during and after first-line therapy.
    Neuro-oncology, 2016, Volume: 18, Issue:7

    Topics: Adult; Aged; Aged, 80 and over; Antibodies, Monoclonal, Humanized; Bevacizumab; Brain Neoplasms; Che

2016
Bevacizumab and temozolomide versus temozolomide alone as neoadjuvant treatment in unresected glioblastoma: the GENOM 009 randomized phase II trial.
    Journal of neuro-oncology, 2016, Volume: 127, Issue:3

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Brain Neoplasms; Dacarbazi

2016
Bevacizumab and temozolomide versus temozolomide alone as neoadjuvant treatment in unresected glioblastoma: the GENOM 009 randomized phase II trial.
    Journal of neuro-oncology, 2016, Volume: 127, Issue:3

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Brain Neoplasms; Dacarbazi

2016
Bevacizumab and temozolomide versus temozolomide alone as neoadjuvant treatment in unresected glioblastoma: the GENOM 009 randomized phase II trial.
    Journal of neuro-oncology, 2016, Volume: 127, Issue:3

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Brain Neoplasms; Dacarbazi

2016
Phase 2 study of concurrent radiotherapy and temozolomide followed by temozolomide and lomustine in the treatment of children with high-grade glioma: a report of the Children's Oncology Group ACNS0423 study.
    Neuro-oncology, 2016, Volume: 18, Issue:10

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Chemoradiotherapy; Chil

2016
Phase 2 study of concurrent radiotherapy and temozolomide followed by temozolomide and lomustine in the treatment of children with high-grade glioma: a report of the Children's Oncology Group ACNS0423 study.
    Neuro-oncology, 2016, Volume: 18, Issue:10

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Chemoradiotherapy; Chil

2016
Phase 2 study of concurrent radiotherapy and temozolomide followed by temozolomide and lomustine in the treatment of children with high-grade glioma: a report of the Children's Oncology Group ACNS0423 study.
    Neuro-oncology, 2016, Volume: 18, Issue:10

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Chemoradiotherapy; Chil

2016
A phase I dose escalation study using simultaneous integrated-boost IMRT with temozolomide in patients with unifocal glioblastoma.
    Cancer radiotherapie : journal de la Societe francaise de radiotherapie oncologique, 2016, Volume: 20, Issue:3

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbaz

2016
A phase I dose escalation study using simultaneous integrated-boost IMRT with temozolomide in patients with unifocal glioblastoma.
    Cancer radiotherapie : journal de la Societe francaise de radiotherapie oncologique, 2016, Volume: 20, Issue:3

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbaz

2016
A phase I dose escalation study using simultaneous integrated-boost IMRT with temozolomide in patients with unifocal glioblastoma.
    Cancer radiotherapie : journal de la Societe francaise de radiotherapie oncologique, 2016, Volume: 20, Issue:3

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbaz

2016
Phase II Study of Radiotherapy and Temsirolimus versus Radiochemotherapy with Temozolomide in Patients with Newly Diagnosed Glioblastoma without MGMT Promoter Hypermethylation (EORTC 26082).
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2016, Oct-01, Volume: 22, Issue:19

    Topics: Adult; Aged; Brain Neoplasms; Chemoradiotherapy; Dacarbazine; DNA Methylation; DNA Modification Meth

2016
Phase II Study of Radiotherapy and Temsirolimus versus Radiochemotherapy with Temozolomide in Patients with Newly Diagnosed Glioblastoma without MGMT Promoter Hypermethylation (EORTC 26082).
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2016, Oct-01, Volume: 22, Issue:19

    Topics: Adult; Aged; Brain Neoplasms; Chemoradiotherapy; Dacarbazine; DNA Methylation; DNA Modification Meth

2016
Phase II Study of Radiotherapy and Temsirolimus versus Radiochemotherapy with Temozolomide in Patients with Newly Diagnosed Glioblastoma without MGMT Promoter Hypermethylation (EORTC 26082).
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2016, Oct-01, Volume: 22, Issue:19

    Topics: Adult; Aged; Brain Neoplasms; Chemoradiotherapy; Dacarbazine; DNA Methylation; DNA Modification Meth

2016
Prognostic value of health-related quality of life for death risk stratification in patients with unresectable glioblastoma.
    Cancer medicine, 2016, Volume: 5, Issue:8

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Brain Neoplasms; Camptothecin; Ch

2016
Prognostic value of health-related quality of life for death risk stratification in patients with unresectable glioblastoma.
    Cancer medicine, 2016, Volume: 5, Issue:8

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Brain Neoplasms; Camptothecin; Ch

2016
Prognostic value of health-related quality of life for death risk stratification in patients with unresectable glioblastoma.
    Cancer medicine, 2016, Volume: 5, Issue:8

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Brain Neoplasms; Camptothecin; Ch

2016
A phase II trial evaluating the effects and intra-tumoral penetration of bortezomib in patients with recurrent malignant gliomas.
    Journal of neuro-oncology, 2016, Volume: 129, Issue:1

    Topics: Adult; Antineoplastic Agents; Bortezomib; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; D

2016
A phase II trial evaluating the effects and intra-tumoral penetration of bortezomib in patients with recurrent malignant gliomas.
    Journal of neuro-oncology, 2016, Volume: 129, Issue:1

    Topics: Adult; Antineoplastic Agents; Bortezomib; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; D

2016
A phase II trial evaluating the effects and intra-tumoral penetration of bortezomib in patients with recurrent malignant gliomas.
    Journal of neuro-oncology, 2016, Volume: 129, Issue:1

    Topics: Adult; Antineoplastic Agents; Bortezomib; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; D

2016
Evaluation of pseudoprogression rates and tumor progression patterns in a phase III trial of bevacizumab plus radiotherapy/temozolomide for newly diagnosed glioblastoma.
    Neuro-oncology, 2016, Volume: 18, Issue:10

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Brain Neoplasms; Chemoradi

2016
Evaluation of pseudoprogression rates and tumor progression patterns in a phase III trial of bevacizumab plus radiotherapy/temozolomide for newly diagnosed glioblastoma.
    Neuro-oncology, 2016, Volume: 18, Issue:10

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Brain Neoplasms; Chemoradi

2016
Evaluation of pseudoprogression rates and tumor progression patterns in a phase III trial of bevacizumab plus radiotherapy/temozolomide for newly diagnosed glioblastoma.
    Neuro-oncology, 2016, Volume: 18, Issue:10

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Brain Neoplasms; Chemoradi

2016
Chemotherapy for adult low-grade gliomas: clinical outcomes by molecular subtype in a phase II study of adjuvant temozolomide.
    Neuro-oncology, 2017, 02-01, Volume: 19, Issue:2

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant; Dacarbazine

2017
Chemotherapy for adult low-grade gliomas: clinical outcomes by molecular subtype in a phase II study of adjuvant temozolomide.
    Neuro-oncology, 2017, 02-01, Volume: 19, Issue:2

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant; Dacarbazine

2017
Chemotherapy for adult low-grade gliomas: clinical outcomes by molecular subtype in a phase II study of adjuvant temozolomide.
    Neuro-oncology, 2017, 02-01, Volume: 19, Issue:2

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant; Dacarbazine

2017
Health-related quality of life in patients with high-risk low-grade glioma (EORTC 22033-26033): a randomised, open-label, phase 3 intergroup study.
    The Lancet. Oncology, 2016, Volume: 17, Issue:11

    Topics: Brain Neoplasms; Dacarbazine; Glioma; Humans; Neoplasm Grading; Prospective Studies; Quality of Life

2016
Health-related quality of life in patients with high-risk low-grade glioma (EORTC 22033-26033): a randomised, open-label, phase 3 intergroup study.
    The Lancet. Oncology, 2016, Volume: 17, Issue:11

    Topics: Brain Neoplasms; Dacarbazine; Glioma; Humans; Neoplasm Grading; Prospective Studies; Quality of Life

2016
Health-related quality of life in patients with high-risk low-grade glioma (EORTC 22033-26033): a randomised, open-label, phase 3 intergroup study.
    The Lancet. Oncology, 2016, Volume: 17, Issue:11

    Topics: Brain Neoplasms; Dacarbazine; Glioma; Humans; Neoplasm Grading; Prospective Studies; Quality of Life

2016
Temozolomide chemotherapy versus radiotherapy in high-risk low-grade glioma (EORTC 22033-26033): a randomised, open-label, phase 3 intergroup study.
    The Lancet. Oncology, 2016, Volume: 17, Issue:11

    Topics: Adult; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Glioma; Humans; Isocitrate D

2016
Temozolomide chemotherapy versus radiotherapy in high-risk low-grade glioma (EORTC 22033-26033): a randomised, open-label, phase 3 intergroup study.
    The Lancet. Oncology, 2016, Volume: 17, Issue:11

    Topics: Adult; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Glioma; Humans; Isocitrate D

2016
Temozolomide chemotherapy versus radiotherapy in high-risk low-grade glioma (EORTC 22033-26033): a randomised, open-label, phase 3 intergroup study.
    The Lancet. Oncology, 2016, Volume: 17, Issue:11

    Topics: Adult; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Glioma; Humans; Isocitrate D

2016
Phase III randomized trial of autologous cytokine-induced killer cell immunotherapy for newly diagnosed glioblastoma in Korea.
    Oncotarget, 2017, Jan-24, Volume: 8, Issue:4

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Combined Modalit

2017
Phase III randomized trial of autologous cytokine-induced killer cell immunotherapy for newly diagnosed glioblastoma in Korea.
    Oncotarget, 2017, Jan-24, Volume: 8, Issue:4

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Combined Modalit

2017
Phase III randomized trial of autologous cytokine-induced killer cell immunotherapy for newly diagnosed glioblastoma in Korea.
    Oncotarget, 2017, Jan-24, Volume: 8, Issue:4

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Combined Modalit

2017
Phase III randomized study of radiation and temozolomide versus radiation and nitrosourea therapy for anaplastic astrocytoma: results of NRG Oncology RTOG 9813.
    Neuro-oncology, 2017, 02-01, Volume: 19, Issue:2

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Astrocytoma; Biomarke

2017
Phase III randomized study of radiation and temozolomide versus radiation and nitrosourea therapy for anaplastic astrocytoma: results of NRG Oncology RTOG 9813.
    Neuro-oncology, 2017, 02-01, Volume: 19, Issue:2

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Astrocytoma; Biomarke

2017
Phase III randomized study of radiation and temozolomide versus radiation and nitrosourea therapy for anaplastic astrocytoma: results of NRG Oncology RTOG 9813.
    Neuro-oncology, 2017, 02-01, Volume: 19, Issue:2

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Astrocytoma; Biomarke

2017
A Phase 2 Trial of Neoadjuvant Temozolomide Followed by Hypofractionated Accelerated Radiation Therapy With Concurrent and Adjuvant Temozolomide for Patients With Glioblastoma.
    International journal of radiation oncology, biology, physics, 2017, 03-01, Volume: 97, Issue:3

    Topics: Adult; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Chemotherapy, Adjuvant

2017
A Phase 2 Trial of Neoadjuvant Temozolomide Followed by Hypofractionated Accelerated Radiation Therapy With Concurrent and Adjuvant Temozolomide for Patients With Glioblastoma.
    International journal of radiation oncology, biology, physics, 2017, 03-01, Volume: 97, Issue:3

    Topics: Adult; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Chemotherapy, Adjuvant

2017
A Phase 2 Trial of Neoadjuvant Temozolomide Followed by Hypofractionated Accelerated Radiation Therapy With Concurrent and Adjuvant Temozolomide for Patients With Glioblastoma.
    International journal of radiation oncology, biology, physics, 2017, 03-01, Volume: 97, Issue:3

    Topics: Adult; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Chemotherapy, Adjuvant

2017
Efficacy and safety results of ABT-414 in combination with radiation and temozolomide in newly diagnosed glioblastoma.
    Neuro-oncology, 2017, Jul-01, Volume: 19, Issue:7

    Topics: Adult; Aged; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Biomarkers, Tumor; Brain Neop

2017
Efficacy and safety results of ABT-414 in combination with radiation and temozolomide in newly diagnosed glioblastoma.
    Neuro-oncology, 2017, Jul-01, Volume: 19, Issue:7

    Topics: Adult; Aged; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Biomarkers, Tumor; Brain Neop

2017
Efficacy and safety results of ABT-414 in combination with radiation and temozolomide in newly diagnosed glioblastoma.
    Neuro-oncology, 2017, Jul-01, Volume: 19, Issue:7

    Topics: Adult; Aged; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Biomarkers, Tumor; Brain Neop

2017
Efficacy and safety results of ABT-414 in combination with radiation and temozolomide in newly diagnosed glioblastoma.
    Neuro-oncology, 2017, Jul-01, Volume: 19, Issue:7

    Topics: Adult; Aged; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Biomarkers, Tumor; Brain Neop

2017
Efficacy and safety results of ABT-414 in combination with radiation and temozolomide in newly diagnosed glioblastoma.
    Neuro-oncology, 2017, Jul-01, Volume: 19, Issue:7

    Topics: Adult; Aged; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Biomarkers, Tumor; Brain Neop

2017
Efficacy and safety results of ABT-414 in combination with radiation and temozolomide in newly diagnosed glioblastoma.
    Neuro-oncology, 2017, Jul-01, Volume: 19, Issue:7

    Topics: Adult; Aged; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Biomarkers, Tumor; Brain Neop

2017
Efficacy and safety results of ABT-414 in combination with radiation and temozolomide in newly diagnosed glioblastoma.
    Neuro-oncology, 2017, Jul-01, Volume: 19, Issue:7

    Topics: Adult; Aged; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Biomarkers, Tumor; Brain Neop

2017
Efficacy and safety results of ABT-414 in combination with radiation and temozolomide in newly diagnosed glioblastoma.
    Neuro-oncology, 2017, Jul-01, Volume: 19, Issue:7

    Topics: Adult; Aged; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Biomarkers, Tumor; Brain Neop

2017
Efficacy and safety results of ABT-414 in combination with radiation and temozolomide in newly diagnosed glioblastoma.
    Neuro-oncology, 2017, Jul-01, Volume: 19, Issue:7

    Topics: Adult; Aged; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Biomarkers, Tumor; Brain Neop

2017
Efficacy and safety results of ABT-414 in combination with radiation and temozolomide in newly diagnosed glioblastoma.
    Neuro-oncology, 2017, Jul-01, Volume: 19, Issue:7

    Topics: Adult; Aged; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Biomarkers, Tumor; Brain Neop

2017
Efficacy and safety results of ABT-414 in combination with radiation and temozolomide in newly diagnosed glioblastoma.
    Neuro-oncology, 2017, Jul-01, Volume: 19, Issue:7

    Topics: Adult; Aged; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Biomarkers, Tumor; Brain Neop

2017
Efficacy and safety results of ABT-414 in combination with radiation and temozolomide in newly diagnosed glioblastoma.
    Neuro-oncology, 2017, Jul-01, Volume: 19, Issue:7

    Topics: Adult; Aged; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Biomarkers, Tumor; Brain Neop

2017
Molecular-Based Recursive Partitioning Analysis Model for Glioblastoma in the Temozolomide Era: A Correlative Analysis Based on NRG Oncology RTOG 0525.
    JAMA oncology, 2017, Jun-01, Volume: 3, Issue:6

    Topics: Antineoplastic Agents, Alkylating; Biomarkers, Tumor; Brain Neoplasms; Combined Modality Therapy; Da

2017
Molecular-Based Recursive Partitioning Analysis Model for Glioblastoma in the Temozolomide Era: A Correlative Analysis Based on NRG Oncology RTOG 0525.
    JAMA oncology, 2017, Jun-01, Volume: 3, Issue:6

    Topics: Antineoplastic Agents, Alkylating; Biomarkers, Tumor; Brain Neoplasms; Combined Modality Therapy; Da

2017
Molecular-Based Recursive Partitioning Analysis Model for Glioblastoma in the Temozolomide Era: A Correlative Analysis Based on NRG Oncology RTOG 0525.
    JAMA oncology, 2017, Jun-01, Volume: 3, Issue:6

    Topics: Antineoplastic Agents, Alkylating; Biomarkers, Tumor; Brain Neoplasms; Combined Modality Therapy; Da

2017
Phase I trial of aflibercept (VEGF trap) with radiation therapy and concomitant and adjuvant temozolomide in patients with high-grade gliomas.
    Journal of neuro-oncology, 2017, Volume: 132, Issue:1

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant; Combined Mo

2017
Phase I trial of aflibercept (VEGF trap) with radiation therapy and concomitant and adjuvant temozolomide in patients with high-grade gliomas.
    Journal of neuro-oncology, 2017, Volume: 132, Issue:1

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant; Combined Mo

2017
Phase I trial of aflibercept (VEGF trap) with radiation therapy and concomitant and adjuvant temozolomide in patients with high-grade gliomas.
    Journal of neuro-oncology, 2017, Volume: 132, Issue:1

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant; Combined Mo

2017
[Outcomes of application of modern first-line chemotherapy regimens in complex treatment of glioblastoma patients].
    Zhurnal voprosy neirokhirurgii imeni N. N. Burdenko, 2016, Volume: 80, Issue:6

    Topics: Antineoplastic Agents; Antineoplastic Protocols; Bevacizumab; Brain Neoplasms; Chemoradiotherapy; Da

2016
[Outcomes of application of modern first-line chemotherapy regimens in complex treatment of glioblastoma patients].
    Zhurnal voprosy neirokhirurgii imeni N. N. Burdenko, 2016, Volume: 80, Issue:6

    Topics: Antineoplastic Agents; Antineoplastic Protocols; Bevacizumab; Brain Neoplasms; Chemoradiotherapy; Da

2016
[Outcomes of application of modern first-line chemotherapy regimens in complex treatment of glioblastoma patients].
    Zhurnal voprosy neirokhirurgii imeni N. N. Burdenko, 2016, Volume: 80, Issue:6

    Topics: Antineoplastic Agents; Antineoplastic Protocols; Bevacizumab; Brain Neoplasms; Chemoradiotherapy; Da

2016
Salvage therapy with bendamustine for temozolomide refractory recurrent anaplastic gliomas: a prospective phase II trial.
    Journal of neuro-oncology, 2017, Volume: 131, Issue:3

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Bendamustine Hydrochloride; Brain Neoplasms; Dacarba

2017
Salvage therapy with bendamustine for temozolomide refractory recurrent anaplastic gliomas: a prospective phase II trial.
    Journal of neuro-oncology, 2017, Volume: 131, Issue:3

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Bendamustine Hydrochloride; Brain Neoplasms; Dacarba

2017
Salvage therapy with bendamustine for temozolomide refractory recurrent anaplastic gliomas: a prospective phase II trial.
    Journal of neuro-oncology, 2017, Volume: 131, Issue:3

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Bendamustine Hydrochloride; Brain Neoplasms; Dacarba

2017
Second-line chemotherapy with fotemustine in temozolomide-pretreated patients with relapsing glioblastoma: a single institution experience.
    Anti-cancer drugs, 2008, Volume: 19, Issue:6

    Topics: Adult; Aged; Brain Neoplasms; Dacarbazine; Female; Glioblastoma; Humans; Male; Middle Aged; Neoplasm

2008
Second-line chemotherapy with fotemustine in temozolomide-pretreated patients with relapsing glioblastoma: a single institution experience.
    Anti-cancer drugs, 2008, Volume: 19, Issue:6

    Topics: Adult; Aged; Brain Neoplasms; Dacarbazine; Female; Glioblastoma; Humans; Male; Middle Aged; Neoplasm

2008
Second-line chemotherapy with fotemustine in temozolomide-pretreated patients with relapsing glioblastoma: a single institution experience.
    Anti-cancer drugs, 2008, Volume: 19, Issue:6

    Topics: Adult; Aged; Brain Neoplasms; Dacarbazine; Female; Glioblastoma; Humans; Male; Middle Aged; Neoplasm

2008
Concurrent radiotherapy with temozolomide followed by adjuvant temozolomide and cis-retinoic acid in children with diffuse intrinsic pontine glioma.
    Neuro-oncology, 2008, Volume: 10, Issue:4

    Topics: Age Factors; Age of Onset; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy P

2008
Concurrent radiotherapy with temozolomide followed by adjuvant temozolomide and cis-retinoic acid in children with diffuse intrinsic pontine glioma.
    Neuro-oncology, 2008, Volume: 10, Issue:4

    Topics: Age Factors; Age of Onset; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy P

2008
Concurrent radiotherapy with temozolomide followed by adjuvant temozolomide and cis-retinoic acid in children with diffuse intrinsic pontine glioma.
    Neuro-oncology, 2008, Volume: 10, Issue:4

    Topics: Age Factors; Age of Onset; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy P

2008
Stem cell-related "self-renewal" signature and high epidermal growth factor receptor expression associated with resistance to concomitant chemoradiotherapy in glioblastoma.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2008, Jun-20, Volume: 26, Issue:18

    Topics: Adult; Adult Stem Cells; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality

2008
Stem cell-related "self-renewal" signature and high epidermal growth factor receptor expression associated with resistance to concomitant chemoradiotherapy in glioblastoma.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2008, Jun-20, Volume: 26, Issue:18

    Topics: Adult; Adult Stem Cells; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality

2008
Stem cell-related "self-renewal" signature and high epidermal growth factor receptor expression associated with resistance to concomitant chemoradiotherapy in glioblastoma.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2008, Jun-20, Volume: 26, Issue:18

    Topics: Adult; Adult Stem Cells; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality

2008
When temozolomide alone fails: adding procarbazine in salvage therapy of glioma.
    The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques, 2008, Volume: 35, Issue:2

    Topics: Adult; Aged; Antineoplastic Agents; Brain Neoplasms; Dacarbazine; Female; Glioma; Humans; Magnetic R

2008
When temozolomide alone fails: adding procarbazine in salvage therapy of glioma.
    The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques, 2008, Volume: 35, Issue:2

    Topics: Adult; Aged; Antineoplastic Agents; Brain Neoplasms; Dacarbazine; Female; Glioma; Humans; Magnetic R

2008
When temozolomide alone fails: adding procarbazine in salvage therapy of glioma.
    The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques, 2008, Volume: 35, Issue:2

    Topics: Adult; Aged; Antineoplastic Agents; Brain Neoplasms; Dacarbazine; Female; Glioma; Humans; Magnetic R

2008
Temozolomide treatment does not affect topiramate and oxcarbazepine plasma concentrations in chronically treated patients with brain tumor-related epilepsy.
    Journal of neuro-oncology, 2008, Volume: 90, Issue:2

    Topics: Adult; Anticonvulsants; Antineoplastic Agents, Alkylating; Brain Neoplasms; Carbamazepine; Dacarbazi

2008
Temozolomide treatment does not affect topiramate and oxcarbazepine plasma concentrations in chronically treated patients with brain tumor-related epilepsy.
    Journal of neuro-oncology, 2008, Volume: 90, Issue:2

    Topics: Adult; Anticonvulsants; Antineoplastic Agents, Alkylating; Brain Neoplasms; Carbamazepine; Dacarbazi

2008
Temozolomide treatment does not affect topiramate and oxcarbazepine plasma concentrations in chronically treated patients with brain tumor-related epilepsy.
    Journal of neuro-oncology, 2008, Volume: 90, Issue:2

    Topics: Adult; Anticonvulsants; Antineoplastic Agents, Alkylating; Brain Neoplasms; Carbamazepine; Dacarbazi

2008
Invasive tumor cells and prognosis in a selected population of patients with glioblastoma multiforme.
    Cancer, 2008, Aug-15, Volume: 113, Issue:4

    Topics: Aged; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Female; Glioblastoma; Humans; Male; M

2008
Invasive tumor cells and prognosis in a selected population of patients with glioblastoma multiforme.
    Cancer, 2008, Aug-15, Volume: 113, Issue:4

    Topics: Aged; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Female; Glioblastoma; Humans; Male; M

2008
Invasive tumor cells and prognosis in a selected population of patients with glioblastoma multiforme.
    Cancer, 2008, Aug-15, Volume: 113, Issue:4

    Topics: Aged; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Female; Glioblastoma; Humans; Male; M

2008
Dose-intensity temozolomide after concurrent chemoradiotherapy in operated high-grade gliomas.
    Journal of neuro-oncology, 2008, Volume: 90, Issue:3

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Dose-Response Relation

2008
Dose-intensity temozolomide after concurrent chemoradiotherapy in operated high-grade gliomas.
    Journal of neuro-oncology, 2008, Volume: 90, Issue:3

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Dose-Response Relation

2008
Dose-intensity temozolomide after concurrent chemoradiotherapy in operated high-grade gliomas.
    Journal of neuro-oncology, 2008, Volume: 90, Issue:3

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Dose-Response Relation

2008
Hypofractionated radiotherapy followed by adjuvant chemotherapy with temozolomide in elderly patients with glioblastoma.
    Journal of neuro-oncology, 2009, Volume: 91, Issue:1

    Topics: Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant; Combined Modality

2009
Hypofractionated radiotherapy followed by adjuvant chemotherapy with temozolomide in elderly patients with glioblastoma.
    Journal of neuro-oncology, 2009, Volume: 91, Issue:1

    Topics: Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant; Combined Modality

2009
Hypofractionated radiotherapy followed by adjuvant chemotherapy with temozolomide in elderly patients with glioblastoma.
    Journal of neuro-oncology, 2009, Volume: 91, Issue:1

    Topics: Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant; Combined Modality

2009
Phase II trial of preirradiation and concurrent temozolomide in patients with newly diagnosed anaplastic oligodendrogliomas and mixed anaplastic oligoastrocytomas: RTOG BR0131.
    Neuro-oncology, 2009, Volume: 11, Issue:2

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents, Phytogenic; Astrocytoma; Brain Neoplasms; Chromosome

2009
Phase II trial of preirradiation and concurrent temozolomide in patients with newly diagnosed anaplastic oligodendrogliomas and mixed anaplastic oligoastrocytomas: RTOG BR0131.
    Neuro-oncology, 2009, Volume: 11, Issue:2

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents, Phytogenic; Astrocytoma; Brain Neoplasms; Chromosome

2009
Phase II trial of preirradiation and concurrent temozolomide in patients with newly diagnosed anaplastic oligodendrogliomas and mixed anaplastic oligoastrocytomas: RTOG BR0131.
    Neuro-oncology, 2009, Volume: 11, Issue:2

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents, Phytogenic; Astrocytoma; Brain Neoplasms; Chromosome

2009
Temozolomide, thalidomide, and whole brain radiation therapy for patients with brain metastasis from metastatic melanoma: a phase II Cytokine Working Group study.
    Cancer, 2008, Oct-15, Volume: 113, Issue:8

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Com

2008
Temozolomide, thalidomide, and whole brain radiation therapy for patients with brain metastasis from metastatic melanoma: a phase II Cytokine Working Group study.
    Cancer, 2008, Oct-15, Volume: 113, Issue:8

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Com

2008
Temozolomide, thalidomide, and whole brain radiation therapy for patients with brain metastasis from metastatic melanoma: a phase II Cytokine Working Group study.
    Cancer, 2008, Oct-15, Volume: 113, Issue:8

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Com

2008
Pediatric phase I and pharmacokinetic study of erlotinib followed by the combination of erlotinib and temozolomide: a Children's Oncology Group Phase I Consortium Study.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2008, Oct-20, Volume: 26, Issue:30

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Area Under Curve; Bone Neoplasms;

2008
Pediatric phase I and pharmacokinetic study of erlotinib followed by the combination of erlotinib and temozolomide: a Children's Oncology Group Phase I Consortium Study.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2008, Oct-20, Volume: 26, Issue:30

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Area Under Curve; Bone Neoplasms;

2008
Pediatric phase I and pharmacokinetic study of erlotinib followed by the combination of erlotinib and temozolomide: a Children's Oncology Group Phase I Consortium Study.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2008, Oct-20, Volume: 26, Issue:30

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Area Under Curve; Bone Neoplasms;

2008
Phase 2 trial of temozolomide using protracted low-dose and whole-brain radiotherapy for nonsmall cell lung cancer and breast cancer patients with brain metastases.
    Cancer, 2008, Nov-01, Volume: 113, Issue:9

    Topics: Aged; Antineoplastic Agents, Alkylating; Bone Marrow; Brain Neoplasms; Breast Neoplasms; Carcinoma,

2008
Phase 2 trial of temozolomide using protracted low-dose and whole-brain radiotherapy for nonsmall cell lung cancer and breast cancer patients with brain metastases.
    Cancer, 2008, Nov-01, Volume: 113, Issue:9

    Topics: Aged; Antineoplastic Agents, Alkylating; Bone Marrow; Brain Neoplasms; Breast Neoplasms; Carcinoma,

2008
Phase 2 trial of temozolomide using protracted low-dose and whole-brain radiotherapy for nonsmall cell lung cancer and breast cancer patients with brain metastases.
    Cancer, 2008, Nov-01, Volume: 113, Issue:9

    Topics: Aged; Antineoplastic Agents, Alkylating; Bone Marrow; Brain Neoplasms; Breast Neoplasms; Carcinoma,

2008
Association of 11C-methionine PET uptake with site of failure after concurrent temozolomide and radiation for primary glioblastoma multiforme.
    International journal of radiation oncology, biology, physics, 2009, Feb-01, Volume: 73, Issue:2

    Topics: Adult; Aged; Algorithms; Antineoplastic Agents, Alkylating; Biopsy; Brain; Brain Neoplasms; Combined

2009
Association of 11C-methionine PET uptake with site of failure after concurrent temozolomide and radiation for primary glioblastoma multiforme.
    International journal of radiation oncology, biology, physics, 2009, Feb-01, Volume: 73, Issue:2

    Topics: Adult; Aged; Algorithms; Antineoplastic Agents, Alkylating; Biopsy; Brain; Brain Neoplasms; Combined

2009
Association of 11C-methionine PET uptake with site of failure after concurrent temozolomide and radiation for primary glioblastoma multiforme.
    International journal of radiation oncology, biology, physics, 2009, Feb-01, Volume: 73, Issue:2

    Topics: Adult; Aged; Algorithms; Antineoplastic Agents, Alkylating; Biopsy; Brain; Brain Neoplasms; Combined

2009
A multicenter phase I trial of interferon-beta and temozolomide combination therapy for high-grade gliomas (INTEGRA Study).
    Japanese journal of clinical oncology, 2008, Volume: 38, Issue:10

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Combined Modality Ther

2008
A multicenter phase I trial of interferon-beta and temozolomide combination therapy for high-grade gliomas (INTEGRA Study).
    Japanese journal of clinical oncology, 2008, Volume: 38, Issue:10

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Combined Modality Ther

2008
A multicenter phase I trial of interferon-beta and temozolomide combination therapy for high-grade gliomas (INTEGRA Study).
    Japanese journal of clinical oncology, 2008, Volume: 38, Issue:10

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Combined Modality Ther

2008
Phase I study of the combination of docetaxel, temozolomide and cisplatin in patients with metastatic melanoma.
    Cancer chemotherapy and pharmacology, 2009, Volume: 64, Issue:1

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Cisplatin; Cohort Stud

2009
Phase I study of the combination of docetaxel, temozolomide and cisplatin in patients with metastatic melanoma.
    Cancer chemotherapy and pharmacology, 2009, Volume: 64, Issue:1

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Cisplatin; Cohort Stud

2009
Phase I study of the combination of docetaxel, temozolomide and cisplatin in patients with metastatic melanoma.
    Cancer chemotherapy and pharmacology, 2009, Volume: 64, Issue:1

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Cisplatin; Cohort Stud

2009
Temozolomide single-agent chemotherapy for newly diagnosed anaplastic oligodendroglioma.
    Journal of neuro-oncology, 2009, Volume: 92, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chromosomes, Human, Pair 1; Chromosomes, Human,

2009
Temozolomide single-agent chemotherapy for newly diagnosed anaplastic oligodendroglioma.
    Journal of neuro-oncology, 2009, Volume: 92, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chromosomes, Human, Pair 1; Chromosomes, Human,

2009
Temozolomide single-agent chemotherapy for newly diagnosed anaplastic oligodendroglioma.
    Journal of neuro-oncology, 2009, Volume: 92, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chromosomes, Human, Pair 1; Chromosomes, Human,

2009
Randomized study of postoperative radiotherapy and simultaneous temozolomide without adjuvant chemotherapy for glioblastoma.
    Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 2008, Volume: 184, Issue:11

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Blood Cell Count; Brain Neoplasms; Combined Modality

2008
Randomized study of postoperative radiotherapy and simultaneous temozolomide without adjuvant chemotherapy for glioblastoma.
    Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 2008, Volume: 184, Issue:11

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Blood Cell Count; Brain Neoplasms; Combined Modality

2008
Randomized study of postoperative radiotherapy and simultaneous temozolomide without adjuvant chemotherapy for glioblastoma.
    Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 2008, Volume: 184, Issue:11

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Blood Cell Count; Brain Neoplasms; Combined Modality

2008
Phase II study of erlotinib plus temozolomide during and after radiation therapy in patients with newly diagnosed glioblastoma multiforme or gliosarcoma.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2009, Feb-01, Volume: 27, Issue:4

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbaz

2009
Phase II study of erlotinib plus temozolomide during and after radiation therapy in patients with newly diagnosed glioblastoma multiforme or gliosarcoma.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2009, Feb-01, Volume: 27, Issue:4

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbaz

2009
Phase II study of erlotinib plus temozolomide during and after radiation therapy in patients with newly diagnosed glioblastoma multiforme or gliosarcoma.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2009, Feb-01, Volume: 27, Issue:4

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbaz

2009
Phase II study of protracted daily temozolomide for low-grade gliomas in adults.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2009, Jan-01, Volume: 15, Issue:1

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Disease-Free Survival;

2009
Phase II study of protracted daily temozolomide for low-grade gliomas in adults.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2009, Jan-01, Volume: 15, Issue:1

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Disease-Free Survival;

2009
Phase II study of protracted daily temozolomide for low-grade gliomas in adults.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2009, Jan-01, Volume: 15, Issue:1

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Disease-Free Survival;

2009
Fotemustine as second-line treatment for recurrent or progressive glioblastoma after concomitant and/or adjuvant temozolomide: a phase II trial of Gruppo Italiano Cooperativo di Neuro-Oncologia (GICNO).
    Cancer chemotherapy and pharmacology, 2009, Volume: 64, Issue:4

    Topics: Adult; Aged; Antineoplastic Agents; Brain Neoplasms; Chemotherapy, Adjuvant; Combined Modality Thera

2009
Fotemustine as second-line treatment for recurrent or progressive glioblastoma after concomitant and/or adjuvant temozolomide: a phase II trial of Gruppo Italiano Cooperativo di Neuro-Oncologia (GICNO).
    Cancer chemotherapy and pharmacology, 2009, Volume: 64, Issue:4

    Topics: Adult; Aged; Antineoplastic Agents; Brain Neoplasms; Chemotherapy, Adjuvant; Combined Modality Thera

2009
Fotemustine as second-line treatment for recurrent or progressive glioblastoma after concomitant and/or adjuvant temozolomide: a phase II trial of Gruppo Italiano Cooperativo di Neuro-Oncologia (GICNO).
    Cancer chemotherapy and pharmacology, 2009, Volume: 64, Issue:4

    Topics: Adult; Aged; Antineoplastic Agents; Brain Neoplasms; Chemotherapy, Adjuvant; Combined Modality Thera

2009
Phase II trial of temozolomide plus o6-benzylguanine in adults with recurrent, temozolomide-resistant malignant glioma.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2009, Mar-10, Volume: 27, Issue:8

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Dacarbazine; Drug Resi

2009
Phase II trial of temozolomide plus o6-benzylguanine in adults with recurrent, temozolomide-resistant malignant glioma.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2009, Mar-10, Volume: 27, Issue:8

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Dacarbazine; Drug Resi

2009
Phase II trial of temozolomide plus o6-benzylguanine in adults with recurrent, temozolomide-resistant malignant glioma.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2009, Mar-10, Volume: 27, Issue:8

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Dacarbazine; Drug Resi

2009
Randomized phase II trial of erlotinib versus temozolomide or carmustine in recurrent glioblastoma: EORTC brain tumor group study 26034.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2009, Mar-10, Volume: 27, Issue:8

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Brain Neoplasms; Carmustine; Dacarbazine; ErbB Recep

2009
Randomized phase II trial of erlotinib versus temozolomide or carmustine in recurrent glioblastoma: EORTC brain tumor group study 26034.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2009, Mar-10, Volume: 27, Issue:8

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Brain Neoplasms; Carmustine; Dacarbazine; ErbB Recep

2009
Randomized phase II trial of erlotinib versus temozolomide or carmustine in recurrent glioblastoma: EORTC brain tumor group study 26034.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2009, Mar-10, Volume: 27, Issue:8

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Brain Neoplasms; Carmustine; Dacarbazine; ErbB Recep

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
    The Lancet. Oncology, 2009, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2009
Phase I trial of temozolomide plus O6-benzylguanine 5-day regimen with recurrent malignant glioma.
    Neuro-oncology, 2009, Volume: 11, Issue:5

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Dacarbazine; Female; G

2009
Phase I trial of temozolomide plus O6-benzylguanine 5-day regimen with recurrent malignant glioma.
    Neuro-oncology, 2009, Volume: 11, Issue:5

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Dacarbazine; Female; G

2009
Phase I trial of temozolomide plus O6-benzylguanine 5-day regimen with recurrent malignant glioma.
    Neuro-oncology, 2009, Volume: 11, Issue:5

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Dacarbazine; Female; G

2009
Early metabolic responses in temozolomide treated low-grade glioma patients.
    Journal of neuro-oncology, 2009, Volume: 95, Issue:1

    Topics: Adult; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Female; Fluorine Radioisotop

2009
Early metabolic responses in temozolomide treated low-grade glioma patients.
    Journal of neuro-oncology, 2009, Volume: 95, Issue:1

    Topics: Adult; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Female; Fluorine Radioisotop

2009
Early metabolic responses in temozolomide treated low-grade glioma patients.
    Journal of neuro-oncology, 2009, Volume: 95, Issue:1

    Topics: Adult; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Female; Fluorine Radioisotop

2009
Phase 1 trial of temozolomide plus irinotecan plus O6-benzylguanine in adults with recurrent malignant glioma.
    Cancer, 2009, Jul-01, Volume: 115, Issue:13

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Camptothecin; Dacarbaz

2009
Phase 1 trial of temozolomide plus irinotecan plus O6-benzylguanine in adults with recurrent malignant glioma.
    Cancer, 2009, Jul-01, Volume: 115, Issue:13

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Camptothecin; Dacarbaz

2009
Phase 1 trial of temozolomide plus irinotecan plus O6-benzylguanine in adults with recurrent malignant glioma.
    Cancer, 2009, Jul-01, Volume: 115, Issue:13

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Camptothecin; Dacarbaz

2009
Randomized phase II trial of chemoradiotherapy followed by either dose-dense or metronomic temozolomide for newly diagnosed glioblastoma.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2009, Aug-10, Volume: 27, Issue:23

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant; Dacarbazine

2009
Randomized phase II trial of chemoradiotherapy followed by either dose-dense or metronomic temozolomide for newly diagnosed glioblastoma.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2009, Aug-10, Volume: 27, Issue:23

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant; Dacarbazine

2009
Randomized phase II trial of chemoradiotherapy followed by either dose-dense or metronomic temozolomide for newly diagnosed glioblastoma.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2009, Aug-10, Volume: 27, Issue:23

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant; Dacarbazine

2009
Phase II trial of temozolomide (TMZ) plus irinotecan (CPT-11) in adults with newly diagnosed glioblastoma multiforme before radiotherapy.
    Journal of neuro-oncology, 2009, Volume: 95, Issue:3

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Phytogenic; Antineoplastic Co

2009
Phase II trial of temozolomide (TMZ) plus irinotecan (CPT-11) in adults with newly diagnosed glioblastoma multiforme before radiotherapy.
    Journal of neuro-oncology, 2009, Volume: 95, Issue:3

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Phytogenic; Antineoplastic Co

2009
Phase II trial of temozolomide (TMZ) plus irinotecan (CPT-11) in adults with newly diagnosed glioblastoma multiforme before radiotherapy.
    Journal of neuro-oncology, 2009, Volume: 95, Issue:3

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Phytogenic; Antineoplastic Co

2009
Talampanel with standard radiation and temozolomide in patients with newly diagnosed glioblastoma: a multicenter phase II trial.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2009, Sep-01, Volume: 27, Issue:25

    Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Antineoplas

2009
Talampanel with standard radiation and temozolomide in patients with newly diagnosed glioblastoma: a multicenter phase II trial.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2009, Sep-01, Volume: 27, Issue:25

    Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Antineoplas

2009
Talampanel with standard radiation and temozolomide in patients with newly diagnosed glioblastoma: a multicenter phase II trial.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2009, Sep-01, Volume: 27, Issue:25

    Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Antineoplas

2009
Clinical outcome of concomitant chemoradiotherapy followed by adjuvant temozolomide therapy for glioblastaomas: single-center experience.
    Clinical neurology and neurosurgery, 2009, Volume: 111, Issue:8

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant;

2009
Clinical outcome of concomitant chemoradiotherapy followed by adjuvant temozolomide therapy for glioblastaomas: single-center experience.
    Clinical neurology and neurosurgery, 2009, Volume: 111, Issue:8

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant;

2009
Clinical outcome of concomitant chemoradiotherapy followed by adjuvant temozolomide therapy for glioblastaomas: single-center experience.
    Clinical neurology and neurosurgery, 2009, Volume: 111, Issue:8

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant;

2009
Prospective evaluation of radiotherapy with concurrent and adjuvant temozolomide in children with newly diagnosed diffuse intrinsic pontine glioma.
    International journal of radiation oncology, biology, physics, 2010, May-01, Volume: 77, Issue:1

    Topics: Adolescent; Antineoplastic Agents, Alkylating; Brain Neoplasms; Child; Child, Preschool; Combined Mo

2010
Prospective evaluation of radiotherapy with concurrent and adjuvant temozolomide in children with newly diagnosed diffuse intrinsic pontine glioma.
    International journal of radiation oncology, biology, physics, 2010, May-01, Volume: 77, Issue:1

    Topics: Adolescent; Antineoplastic Agents, Alkylating; Brain Neoplasms; Child; Child, Preschool; Combined Mo

2010
Prospective evaluation of radiotherapy with concurrent and adjuvant temozolomide in children with newly diagnosed diffuse intrinsic pontine glioma.
    International journal of radiation oncology, biology, physics, 2010, May-01, Volume: 77, Issue:1

    Topics: Adolescent; Antineoplastic Agents, Alkylating; Brain Neoplasms; Child; Child, Preschool; Combined Mo

2010
Extended-schedule dose-dense temozolomide in refractory gliomas.
    Journal of neuro-oncology, 2010, Volume: 96, Issue:3

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Drug Administration Sc

2010
Extended-schedule dose-dense temozolomide in refractory gliomas.
    Journal of neuro-oncology, 2010, Volume: 96, Issue:3

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Drug Administration Sc

2010
Extended-schedule dose-dense temozolomide in refractory gliomas.
    Journal of neuro-oncology, 2010, Volume: 96, Issue:3

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Drug Administration Sc

2010
Two phase II trials of temozolomide with interferon-alpha2b (pegylated and non-pegylated) in patients with recurrent glioblastoma multiforme.
    British journal of cancer, 2009, Aug-18, Volume: 101, Issue:4

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Dacarbazin

2009
Two phase II trials of temozolomide with interferon-alpha2b (pegylated and non-pegylated) in patients with recurrent glioblastoma multiforme.
    British journal of cancer, 2009, Aug-18, Volume: 101, Issue:4

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Dacarbazin

2009
Two phase II trials of temozolomide with interferon-alpha2b (pegylated and non-pegylated) in patients with recurrent glioblastoma multiforme.
    British journal of cancer, 2009, Aug-18, Volume: 101, Issue:4

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Dacarbazin

2009
A phase I dose-escalation study (ISIDE-BT-1) of accelerated IMRT with temozolomide in patients with glioblastoma.
    International journal of radiation oncology, biology, physics, 2010, May-01, Volume: 77, Issue:1

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Dose Fractionation, Ra

2010
A phase I dose-escalation study (ISIDE-BT-1) of accelerated IMRT with temozolomide in patients with glioblastoma.
    International journal of radiation oncology, biology, physics, 2010, May-01, Volume: 77, Issue:1

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Dose Fractionation, Ra

2010
A phase I dose-escalation study (ISIDE-BT-1) of accelerated IMRT with temozolomide in patients with glioblastoma.
    International journal of radiation oncology, biology, physics, 2010, May-01, Volume: 77, Issue:1

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Dose Fractionation, Ra

2010
Imatinib in combination with hydroxyurea versus hydroxyurea alone as oral therapy in patients with progressive pretreated glioblastoma resistant to standard dose temozolomide.
    Journal of neuro-oncology, 2010, Volume: 96, Issue:3

    Topics: Adult; Age Factors; Aged; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Benzamides; Brai

2010
Imatinib in combination with hydroxyurea versus hydroxyurea alone as oral therapy in patients with progressive pretreated glioblastoma resistant to standard dose temozolomide.
    Journal of neuro-oncology, 2010, Volume: 96, Issue:3

    Topics: Adult; Age Factors; Aged; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Benzamides; Brai

2010
Imatinib in combination with hydroxyurea versus hydroxyurea alone as oral therapy in patients with progressive pretreated glioblastoma resistant to standard dose temozolomide.
    Journal of neuro-oncology, 2010, Volume: 96, Issue:3

    Topics: Adult; Age Factors; Aged; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Benzamides; Brai

2010
Radiotherapy and concomitant temozolomide during the first and last weeks in high grade gliomas: long-term analysis of a phase II study.
    Journal of neuro-oncology, 2010, Volume: 97, Issue:1

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbaz

2010
Radiotherapy and concomitant temozolomide during the first and last weeks in high grade gliomas: long-term analysis of a phase II study.
    Journal of neuro-oncology, 2010, Volume: 97, Issue:1

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbaz

2010
Radiotherapy and concomitant temozolomide during the first and last weeks in high grade gliomas: long-term analysis of a phase II study.
    Journal of neuro-oncology, 2010, Volume: 97, Issue:1

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbaz

2010
Promoter methylation and expression analysis of MGMT in advanced pediatric brain tumors.
    Oncology reports, 2009, Volume: 22, Issue:4

    Topics: Adolescent; Antineoplastic Agents, Alkylating; Brain Neoplasms; Child; Child, Preschool; Dacarbazine

2009
Promoter methylation and expression analysis of MGMT in advanced pediatric brain tumors.
    Oncology reports, 2009, Volume: 22, Issue:4

    Topics: Adolescent; Antineoplastic Agents, Alkylating; Brain Neoplasms; Child; Child, Preschool; Dacarbazine

2009
Promoter methylation and expression analysis of MGMT in advanced pediatric brain tumors.
    Oncology reports, 2009, Volume: 22, Issue:4

    Topics: Adolescent; Antineoplastic Agents, Alkylating; Brain Neoplasms; Child; Child, Preschool; Dacarbazine

2009
Dose-dense temozolomide regimen for the treatment of brain metastases from melanoma, breast cancer, or lung cancer not amenable to surgery or radiosurgery: a multicenter phase II study.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2010, Volume: 21, Issue:3

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Breast Neoplasms; Carcinoma, Non-Small-Cell Lung

2010
Dose-dense temozolomide regimen for the treatment of brain metastases from melanoma, breast cancer, or lung cancer not amenable to surgery or radiosurgery: a multicenter phase II study.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2010, Volume: 21, Issue:3

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Breast Neoplasms; Carcinoma, Non-Small-Cell Lung

2010
Dose-dense temozolomide regimen for the treatment of brain metastases from melanoma, breast cancer, or lung cancer not amenable to surgery or radiosurgery: a multicenter phase II study.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2010, Volume: 21, Issue:3

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Breast Neoplasms; Carcinoma, Non-Small-Cell Lung

2010
Population-based study of pseudoprogression after chemoradiotherapy in GBM.
    The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques, 2009, Volume: 36, Issue:5

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Brai

2009
Population-based study of pseudoprogression after chemoradiotherapy in GBM.
    The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques, 2009, Volume: 36, Issue:5

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Brai

2009
Population-based study of pseudoprogression after chemoradiotherapy in GBM.
    The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques, 2009, Volume: 36, Issue:5

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Brai

2009
Chemoradiotherapy of newly diagnosed glioblastoma with intensified temozolomide.
    International journal of radiation oncology, biology, physics, 2010, Jul-01, Volume: 77, Issue:3

    Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents, Alkylating; Brain Neopl

2010
Chemoradiotherapy of newly diagnosed glioblastoma with intensified temozolomide.
    International journal of radiation oncology, biology, physics, 2010, Jul-01, Volume: 77, Issue:3

    Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents, Alkylating; Brain Neopl

2010
Chemoradiotherapy of newly diagnosed glioblastoma with intensified temozolomide.
    International journal of radiation oncology, biology, physics, 2010, Jul-01, Volume: 77, Issue:3

    Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents, Alkylating; Brain Neopl

2010
A phase II study of cisplatin and temozolomide in heavily pre-treated patients with temozolomide-refractory high-grade malignant glioma.
    Anticancer research, 2009, Volume: 29, Issue:10

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Cisplatin;

2009
A phase II study of cisplatin and temozolomide in heavily pre-treated patients with temozolomide-refractory high-grade malignant glioma.
    Anticancer research, 2009, Volume: 29, Issue:10

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Cisplatin;

2009
A phase II study of cisplatin and temozolomide in heavily pre-treated patients with temozolomide-refractory high-grade malignant glioma.
    Anticancer research, 2009, Volume: 29, Issue:10

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Cisplatin;

2009
The neuropharmacokinetics of temozolomide in patients with resectable brain tumors: potential implications for the current approach to chemoradiation.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2009, Nov-15, Volume: 15, Issue:22

    Topics: Administration, Oral; Aged; Antineoplastic Agents, Alkylating; Area Under Curve; Brain Neoplasms; Co

2009
The neuropharmacokinetics of temozolomide in patients with resectable brain tumors: potential implications for the current approach to chemoradiation.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2009, Nov-15, Volume: 15, Issue:22

    Topics: Administration, Oral; Aged; Antineoplastic Agents, Alkylating; Area Under Curve; Brain Neoplasms; Co

2009
The neuropharmacokinetics of temozolomide in patients with resectable brain tumors: potential implications for the current approach to chemoradiation.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2009, Nov-15, Volume: 15, Issue:22

    Topics: Administration, Oral; Aged; Antineoplastic Agents, Alkylating; Area Under Curve; Brain Neoplasms; Co

2009
NOA-04 randomized phase III trial of sequential radiochemotherapy of anaplastic glioma with procarbazine, lomustine, and vincristine or temozolomide.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2009, Dec-10, Volume: 27, Issue:35

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Brai

2009
NOA-04 randomized phase III trial of sequential radiochemotherapy of anaplastic glioma with procarbazine, lomustine, and vincristine or temozolomide.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2009, Dec-10, Volume: 27, Issue:35

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Brai

2009
NOA-04 randomized phase III trial of sequential radiochemotherapy of anaplastic glioma with procarbazine, lomustine, and vincristine or temozolomide.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2009, Dec-10, Volume: 27, Issue:35

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Brai

2009
IDH1 mutations in low-grade astrocytomas predict survival but not response to temozolomide.
    Neurology, 2009, Nov-24, Volume: 73, Issue:21

    Topics: Adult; Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neoplasms; Cohort Studies; Dacarbazine;

2009
IDH1 mutations in low-grade astrocytomas predict survival but not response to temozolomide.
    Neurology, 2009, Nov-24, Volume: 73, Issue:21

    Topics: Adult; Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neoplasms; Cohort Studies; Dacarbazine;

2009
IDH1 mutations in low-grade astrocytomas predict survival but not response to temozolomide.
    Neurology, 2009, Nov-24, Volume: 73, Issue:21

    Topics: Adult; Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neoplasms; Cohort Studies; Dacarbazine;

2009
EORTC study 26041-22041: phase I/II study on concomitant and adjuvant temozolomide (TMZ) and radiotherapy (RT) with PTK787/ZK222584 (PTK/ZK) in newly diagnosed glioblastoma.
    European journal of cancer (Oxford, England : 1990), 2010, Volume: 46, Issue:2

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Chemotherapy, Adjuvant

2010
EORTC study 26041-22041: phase I/II study on concomitant and adjuvant temozolomide (TMZ) and radiotherapy (RT) with PTK787/ZK222584 (PTK/ZK) in newly diagnosed glioblastoma.
    European journal of cancer (Oxford, England : 1990), 2010, Volume: 46, Issue:2

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Chemotherapy, Adjuvant

2010
EORTC study 26041-22041: phase I/II study on concomitant and adjuvant temozolomide (TMZ) and radiotherapy (RT) with PTK787/ZK222584 (PTK/ZK) in newly diagnosed glioblastoma.
    European journal of cancer (Oxford, England : 1990), 2010, Volume: 46, Issue:2

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Chemotherapy, Adjuvant

2010
Phase II trial of erlotinib with temozolomide and radiation in patients with newly diagnosed glioblastoma multiforme.
    Journal of neuro-oncology, 2010, Volume: 98, Issue:1

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Pro

2010
Phase II trial of erlotinib with temozolomide and radiation in patients with newly diagnosed glioblastoma multiforme.
    Journal of neuro-oncology, 2010, Volume: 98, Issue:1

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Pro

2010
Phase II trial of erlotinib with temozolomide and radiation in patients with newly diagnosed glioblastoma multiforme.
    Journal of neuro-oncology, 2010, Volume: 98, Issue:1

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Pro

2010
[A multicenter randomized controlled study of temozolomide in 97 patients with malignant brain glioma].
    Zhonghua yi xue za zhi, 2009, Aug-04, Volume: 89, Issue:29

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Daca

2009
[A multicenter randomized controlled study of temozolomide in 97 patients with malignant brain glioma].
    Zhonghua yi xue za zhi, 2009, Aug-04, Volume: 89, Issue:29

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Daca

2009
[A multicenter randomized controlled study of temozolomide in 97 patients with malignant brain glioma].
    Zhonghua yi xue za zhi, 2009, Aug-04, Volume: 89, Issue:29

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Daca

2009
Intra-arterial chemotherapy with osmotic blood-brain barrier disruption for aggressive oligodendroglial tumors: results of a phase I study.
    Neurosurgery, 2010, Volume: 66, Issue:1

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Blood-Brain Barrier; Brain Neoplasms; Carbopl

2010
Intra-arterial chemotherapy with osmotic blood-brain barrier disruption for aggressive oligodendroglial tumors: results of a phase I study.
    Neurosurgery, 2010, Volume: 66, Issue:1

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Blood-Brain Barrier; Brain Neoplasms; Carbopl

2010
Intra-arterial chemotherapy with osmotic blood-brain barrier disruption for aggressive oligodendroglial tumors: results of a phase I study.
    Neurosurgery, 2010, Volume: 66, Issue:1

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Blood-Brain Barrier; Brain Neoplasms; Carbopl

2010
Phase I study of vandetanib with radiotherapy and temozolomide for newly diagnosed glioblastoma.
    International journal of radiation oncology, biology, physics, 2010, Sep-01, Volume: 78, Issue:1

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Combined Modality Ther

2010
Phase I study of vandetanib with radiotherapy and temozolomide for newly diagnosed glioblastoma.
    International journal of radiation oncology, biology, physics, 2010, Sep-01, Volume: 78, Issue:1

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Combined Modality Ther

2010
Phase I study of vandetanib with radiotherapy and temozolomide for newly diagnosed glioblastoma.
    International journal of radiation oncology, biology, physics, 2010, Sep-01, Volume: 78, Issue:1

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Combined Modality Ther

2010
Enzastaurin plus temozolomide with radiation therapy in glioblastoma multiforme: a phase I study.
    Neuro-oncology, 2010, Volume: 12, Issue:6

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Cohort Studies; Combin

2010
Enzastaurin plus temozolomide with radiation therapy in glioblastoma multiforme: a phase I study.
    Neuro-oncology, 2010, Volume: 12, Issue:6

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Cohort Studies; Combin

2010
Enzastaurin plus temozolomide with radiation therapy in glioblastoma multiforme: a phase I study.
    Neuro-oncology, 2010, Volume: 12, Issue:6

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Cohort Studies; Combin

2010
Six-month progression-free survival as an alternative primary efficacy endpoint to overall survival in newly diagnosed glioblastoma patients receiving temozolomide.
    Neuro-oncology, 2010, Volume: 12, Issue:3

    Topics: Adult; Aged; Antineoplastic Agents; Brain Neoplasms; Dacarbazine; Disease-Free Survival; Female; Gli

2010
Six-month progression-free survival as an alternative primary efficacy endpoint to overall survival in newly diagnosed glioblastoma patients receiving temozolomide.
    Neuro-oncology, 2010, Volume: 12, Issue:3

    Topics: Adult; Aged; Antineoplastic Agents; Brain Neoplasms; Dacarbazine; Disease-Free Survival; Female; Gli

2010
Six-month progression-free survival as an alternative primary efficacy endpoint to overall survival in newly diagnosed glioblastoma patients receiving temozolomide.
    Neuro-oncology, 2010, Volume: 12, Issue:3

    Topics: Adult; Aged; Antineoplastic Agents; Brain Neoplasms; Dacarbazine; Disease-Free Survival; Female; Gli

2010
Phase II trial of low-dose continuous (metronomic) treatment of temozolomide for recurrent glioblastoma.
    Neuro-oncology, 2010, Volume: 12, Issue:3

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Disease-Free Survival;

2010
Phase II trial of low-dose continuous (metronomic) treatment of temozolomide for recurrent glioblastoma.
    Neuro-oncology, 2010, Volume: 12, Issue:3

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Disease-Free Survival;

2010
Phase II trial of low-dose continuous (metronomic) treatment of temozolomide for recurrent glioblastoma.
    Neuro-oncology, 2010, Volume: 12, Issue:3

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Disease-Free Survival;

2010
A phase 1 trial of ABT-510 concurrent with standard chemoradiation for patients with newly diagnosed glioblastoma.
    Archives of neurology, 2010, Volume: 67, Issue:3

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Brai

2010
A phase 1 trial of ABT-510 concurrent with standard chemoradiation for patients with newly diagnosed glioblastoma.
    Archives of neurology, 2010, Volume: 67, Issue:3

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Brai

2010
A phase 1 trial of ABT-510 concurrent with standard chemoradiation for patients with newly diagnosed glioblastoma.
    Archives of neurology, 2010, Volume: 67, Issue:3

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Brai

2010
Phase II trial of continuous dose-intense temozolomide in recurrent malignant glioma: RESCUE study.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2010, Apr-20, Volume: 28, Issue:12

    Topics: Adult; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Chemotherapy, Adjuvant; Dacarbazi

2010
Phase II trial of continuous dose-intense temozolomide in recurrent malignant glioma: RESCUE study.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2010, Apr-20, Volume: 28, Issue:12

    Topics: Adult; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Chemotherapy, Adjuvant; Dacarbazi

2010
Phase II trial of continuous dose-intense temozolomide in recurrent malignant glioma: RESCUE study.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2010, Apr-20, Volume: 28, Issue:12

    Topics: Adult; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Chemotherapy, Adjuvant; Dacarbazi

2010
Phase II trial of continuous dose-intense temozolomide in recurrent malignant glioma: RESCUE study.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2010, Apr-20, Volume: 28, Issue:12

    Topics: Adult; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Chemotherapy, Adjuvant; Dacarbazi

2010
Phase II trial of continuous dose-intense temozolomide in recurrent malignant glioma: RESCUE study.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2010, Apr-20, Volume: 28, Issue:12

    Topics: Adult; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Chemotherapy, Adjuvant; Dacarbazi

2010
Phase II trial of continuous dose-intense temozolomide in recurrent malignant glioma: RESCUE study.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2010, Apr-20, Volume: 28, Issue:12

    Topics: Adult; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Chemotherapy, Adjuvant; Dacarbazi

2010
Phase II trial of continuous dose-intense temozolomide in recurrent malignant glioma: RESCUE study.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2010, Apr-20, Volume: 28, Issue:12

    Topics: Adult; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Chemotherapy, Adjuvant; Dacarbazi

2010
Phase II trial of continuous dose-intense temozolomide in recurrent malignant glioma: RESCUE study.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2010, Apr-20, Volume: 28, Issue:12

    Topics: Adult; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Chemotherapy, Adjuvant; Dacarbazi

2010
Phase II trial of continuous dose-intense temozolomide in recurrent malignant glioma: RESCUE study.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2010, Apr-20, Volume: 28, Issue:12

    Topics: Adult; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Chemotherapy, Adjuvant; Dacarbazi

2010
Phase II trial of continuous dose-intense temozolomide in recurrent malignant glioma: RESCUE study.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2010, Apr-20, Volume: 28, Issue:12

    Topics: Adult; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Chemotherapy, Adjuvant; Dacarbazi

2010
Phase II trial of continuous dose-intense temozolomide in recurrent malignant glioma: RESCUE study.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2010, Apr-20, Volume: 28, Issue:12

    Topics: Adult; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Chemotherapy, Adjuvant; Dacarbazi

2010
Phase II trial of continuous dose-intense temozolomide in recurrent malignant glioma: RESCUE study.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2010, Apr-20, Volume: 28, Issue:12

    Topics: Adult; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Chemotherapy, Adjuvant; Dacarbazi

2010
A Phase II study of anti-epidermal growth factor receptor radioimmunotherapy in the treatment of glioblastoma multiforme.
    Journal of neurosurgery, 2010, Volume: 113, Issue:2

    Topics: Adult; Aged; Antibodies, Monoclonal; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Mo

2010
A Phase II study of anti-epidermal growth factor receptor radioimmunotherapy in the treatment of glioblastoma multiforme.
    Journal of neurosurgery, 2010, Volume: 113, Issue:2

    Topics: Adult; Aged; Antibodies, Monoclonal; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Mo

2010
A Phase II study of anti-epidermal growth factor receptor radioimmunotherapy in the treatment of glioblastoma multiforme.
    Journal of neurosurgery, 2010, Volume: 113, Issue:2

    Topics: Adult; Aged; Antibodies, Monoclonal; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Mo

2010
Effects of concomitant temozolomide and radiation therapies on WT1-specific T-cells in malignant glioma.
    Japanese journal of clinical oncology, 2010, Volume: 40, Issue:5

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cancer Vaccines; Combined Modality

2010
Effects of concomitant temozolomide and radiation therapies on WT1-specific T-cells in malignant glioma.
    Japanese journal of clinical oncology, 2010, Volume: 40, Issue:5

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cancer Vaccines; Combined Modality

2010
Effects of concomitant temozolomide and radiation therapies on WT1-specific T-cells in malignant glioma.
    Japanese journal of clinical oncology, 2010, Volume: 40, Issue:5

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cancer Vaccines; Combined Modality

2010
A phase II trial of primary temozolomide in patients with grade III oligodendroglial brain tumors.
    Neuro-oncology, 2010, Volume: 12, Issue:5

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Brain Neoplasms; Chromosomes, Human, Pair 1; Chromos

2010
A phase II trial of primary temozolomide in patients with grade III oligodendroglial brain tumors.
    Neuro-oncology, 2010, Volume: 12, Issue:5

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Brain Neoplasms; Chromosomes, Human, Pair 1; Chromos

2010
A phase II trial of primary temozolomide in patients with grade III oligodendroglial brain tumors.
    Neuro-oncology, 2010, Volume: 12, Issue:5

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Brain Neoplasms; Chromosomes, Human, Pair 1; Chromos

2010
Cetuximab, bevacizumab, and irinotecan for patients with primary glioblastoma and progression after radiation therapy and temozolomide: a phase II trial.
    Neuro-oncology, 2010, Volume: 12, Issue:5

    Topics: Adult; Aged; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chem

2010
Cetuximab, bevacizumab, and irinotecan for patients with primary glioblastoma and progression after radiation therapy and temozolomide: a phase II trial.
    Neuro-oncology, 2010, Volume: 12, Issue:5

    Topics: Adult; Aged; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chem

2010
Cetuximab, bevacizumab, and irinotecan for patients with primary glioblastoma and progression after radiation therapy and temozolomide: a phase II trial.
    Neuro-oncology, 2010, Volume: 12, Issue:5

    Topics: Adult; Aged; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chem

2010
Phase I/II dose escalation trial of concurrent temozolomide and whole brain radiation therapy for multiple brain metastasis.
    Journal of neuro-oncology, 2010, Volume: 100, Issue:2

    Topics: Aged; Aged, 80 and over; Antineoplastic Agents; Brain Neoplasms; Combined Modality Therapy; Cranial

2010
Phase I/II dose escalation trial of concurrent temozolomide and whole brain radiation therapy for multiple brain metastasis.
    Journal of neuro-oncology, 2010, Volume: 100, Issue:2

    Topics: Aged; Aged, 80 and over; Antineoplastic Agents; Brain Neoplasms; Combined Modality Therapy; Cranial

2010
Phase I/II dose escalation trial of concurrent temozolomide and whole brain radiation therapy for multiple brain metastasis.
    Journal of neuro-oncology, 2010, Volume: 100, Issue:2

    Topics: Aged; Aged, 80 and over; Antineoplastic Agents; Brain Neoplasms; Combined Modality Therapy; Cranial

2010
Whole-brain radiation therapy plus concomitant temozolomide for the treatment of brain metastases from non-small-cell lung cancer: a randomized, open-label phase II study.
    Clinical lung cancer, 2010, Volume: 11, Issue:3

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Carcinoma, Non-Small-Cell Lung; Com

2010
Whole-brain radiation therapy plus concomitant temozolomide for the treatment of brain metastases from non-small-cell lung cancer: a randomized, open-label phase II study.
    Clinical lung cancer, 2010, Volume: 11, Issue:3

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Carcinoma, Non-Small-Cell Lung; Com

2010
Whole-brain radiation therapy plus concomitant temozolomide for the treatment of brain metastases from non-small-cell lung cancer: a randomized, open-label phase II study.
    Clinical lung cancer, 2010, Volume: 11, Issue:3

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Carcinoma, Non-Small-Cell Lung; Com

2010
Phase I/IIa study of cilengitide and temozolomide with concomitant radiotherapy followed by cilengitide and temozolomide maintenance therapy in patients with newly diagnosed glioblastoma.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2010, Jun-01, Volume: 28, Issue:16

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Biopsy, Needle; Brain Neoplasms; Combined Modality T

2010
Phase I/IIa study of cilengitide and temozolomide with concomitant radiotherapy followed by cilengitide and temozolomide maintenance therapy in patients with newly diagnosed glioblastoma.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2010, Jun-01, Volume: 28, Issue:16

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Biopsy, Needle; Brain Neoplasms; Combined Modality T

2010
Phase I/IIa study of cilengitide and temozolomide with concomitant radiotherapy followed by cilengitide and temozolomide maintenance therapy in patients with newly diagnosed glioblastoma.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2010, Jun-01, Volume: 28, Issue:16

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Biopsy, Needle; Brain Neoplasms; Combined Modality T

2010
Effect of CYP3A-inducing anti-epileptics on sorafenib exposure: results of a phase II study of sorafenib plus daily temozolomide in adults with recurrent glioblastoma.
    Journal of neuro-oncology, 2011, Volume: 101, Issue:1

    Topics: Adult; Aged; Anticonvulsants; Antineoplastic Combined Chemotherapy Protocols; Benzenesulfonates; Bra

2011
Effect of CYP3A-inducing anti-epileptics on sorafenib exposure: results of a phase II study of sorafenib plus daily temozolomide in adults with recurrent glioblastoma.
    Journal of neuro-oncology, 2011, Volume: 101, Issue:1

    Topics: Adult; Aged; Anticonvulsants; Antineoplastic Combined Chemotherapy Protocols; Benzenesulfonates; Bra

2011
Effect of CYP3A-inducing anti-epileptics on sorafenib exposure: results of a phase II study of sorafenib plus daily temozolomide in adults with recurrent glioblastoma.
    Journal of neuro-oncology, 2011, Volume: 101, Issue:1

    Topics: Adult; Aged; Anticonvulsants; Antineoplastic Combined Chemotherapy Protocols; Benzenesulfonates; Bra

2011
Concurrent radiotherapy and temozolomide followed by temozolomide and sorafenib in the first-line treatment of patients with glioblastoma multiforme.
    Cancer, 2010, Aug-01, Volume: 116, Issue:15

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Benz

2010
Concurrent radiotherapy and temozolomide followed by temozolomide and sorafenib in the first-line treatment of patients with glioblastoma multiforme.
    Cancer, 2010, Aug-01, Volume: 116, Issue:15

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Benz

2010
Concurrent radiotherapy and temozolomide followed by temozolomide and sorafenib in the first-line treatment of patients with glioblastoma multiforme.
    Cancer, 2010, Aug-01, Volume: 116, Issue:15

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Benz

2010
A multi-institution phase II study of poly-ICLC and radiotherapy with concurrent and adjuvant temozolomide in adults with newly diagnosed glioblastoma.
    Neuro-oncology, 2010, Volume: 12, Issue:10

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carboxymethylcellulose

2010
A multi-institution phase II study of poly-ICLC and radiotherapy with concurrent and adjuvant temozolomide in adults with newly diagnosed glioblastoma.
    Neuro-oncology, 2010, Volume: 12, Issue:10

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carboxymethylcellulose

2010
A multi-institution phase II study of poly-ICLC and radiotherapy with concurrent and adjuvant temozolomide in adults with newly diagnosed glioblastoma.
    Neuro-oncology, 2010, Volume: 12, Issue:10

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carboxymethylcellulose

2010
A multi-institution phase II study of poly-ICLC and radiotherapy with concurrent and adjuvant temozolomide in adults with newly diagnosed glioblastoma.
    Neuro-oncology, 2010, Volume: 12, Issue:10

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carboxymethylcellulose

2010
A multi-institution phase II study of poly-ICLC and radiotherapy with concurrent and adjuvant temozolomide in adults with newly diagnosed glioblastoma.
    Neuro-oncology, 2010, Volume: 12, Issue:10

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carboxymethylcellulose

2010
A multi-institution phase II study of poly-ICLC and radiotherapy with concurrent and adjuvant temozolomide in adults with newly diagnosed glioblastoma.
    Neuro-oncology, 2010, Volume: 12, Issue:10

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carboxymethylcellulose

2010
A multi-institution phase II study of poly-ICLC and radiotherapy with concurrent and adjuvant temozolomide in adults with newly diagnosed glioblastoma.
    Neuro-oncology, 2010, Volume: 12, Issue:10

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carboxymethylcellulose

2010
A multi-institution phase II study of poly-ICLC and radiotherapy with concurrent and adjuvant temozolomide in adults with newly diagnosed glioblastoma.
    Neuro-oncology, 2010, Volume: 12, Issue:10

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carboxymethylcellulose

2010
A multi-institution phase II study of poly-ICLC and radiotherapy with concurrent and adjuvant temozolomide in adults with newly diagnosed glioblastoma.
    Neuro-oncology, 2010, Volume: 12, Issue:10

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carboxymethylcellulose

2010
A multi-institution phase II study of poly-ICLC and radiotherapy with concurrent and adjuvant temozolomide in adults with newly diagnosed glioblastoma.
    Neuro-oncology, 2010, Volume: 12, Issue:10

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carboxymethylcellulose

2010
A multi-institution phase II study of poly-ICLC and radiotherapy with concurrent and adjuvant temozolomide in adults with newly diagnosed glioblastoma.
    Neuro-oncology, 2010, Volume: 12, Issue:10

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carboxymethylcellulose

2010
A multi-institution phase II study of poly-ICLC and radiotherapy with concurrent and adjuvant temozolomide in adults with newly diagnosed glioblastoma.
    Neuro-oncology, 2010, Volume: 12, Issue:10

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carboxymethylcellulose

2010
A multi-institution phase II study of poly-ICLC and radiotherapy with concurrent and adjuvant temozolomide in adults with newly diagnosed glioblastoma.
    Neuro-oncology, 2010, Volume: 12, Issue:10

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carboxymethylcellulose

2010
A multi-institution phase II study of poly-ICLC and radiotherapy with concurrent and adjuvant temozolomide in adults with newly diagnosed glioblastoma.
    Neuro-oncology, 2010, Volume: 12, Issue:10

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carboxymethylcellulose

2010
A multi-institution phase II study of poly-ICLC and radiotherapy with concurrent and adjuvant temozolomide in adults with newly diagnosed glioblastoma.
    Neuro-oncology, 2010, Volume: 12, Issue:10

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carboxymethylcellulose

2010
A multi-institution phase II study of poly-ICLC and radiotherapy with concurrent and adjuvant temozolomide in adults with newly diagnosed glioblastoma.
    Neuro-oncology, 2010, Volume: 12, Issue:10

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carboxymethylcellulose

2010
A multi-institution phase II study of poly-ICLC and radiotherapy with concurrent and adjuvant temozolomide in adults with newly diagnosed glioblastoma.
    Neuro-oncology, 2010, Volume: 12, Issue:10

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carboxymethylcellulose

2010
A multi-institution phase II study of poly-ICLC and radiotherapy with concurrent and adjuvant temozolomide in adults with newly diagnosed glioblastoma.
    Neuro-oncology, 2010, Volume: 12, Issue:10

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carboxymethylcellulose

2010
A multi-institution phase II study of poly-ICLC and radiotherapy with concurrent and adjuvant temozolomide in adults with newly diagnosed glioblastoma.
    Neuro-oncology, 2010, Volume: 12, Issue:10

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carboxymethylcellulose

2010
A multi-institution phase II study of poly-ICLC and radiotherapy with concurrent and adjuvant temozolomide in adults with newly diagnosed glioblastoma.
    Neuro-oncology, 2010, Volume: 12, Issue:10

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carboxymethylcellulose

2010
A multi-institution phase II study of poly-ICLC and radiotherapy with concurrent and adjuvant temozolomide in adults with newly diagnosed glioblastoma.
    Neuro-oncology, 2010, Volume: 12, Issue:10

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carboxymethylcellulose

2010
A multi-institution phase II study of poly-ICLC and radiotherapy with concurrent and adjuvant temozolomide in adults with newly diagnosed glioblastoma.
    Neuro-oncology, 2010, Volume: 12, Issue:10

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carboxymethylcellulose

2010
A multi-institution phase II study of poly-ICLC and radiotherapy with concurrent and adjuvant temozolomide in adults with newly diagnosed glioblastoma.
    Neuro-oncology, 2010, Volume: 12, Issue:10

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carboxymethylcellulose

2010
A multi-institution phase II study of poly-ICLC and radiotherapy with concurrent and adjuvant temozolomide in adults with newly diagnosed glioblastoma.
    Neuro-oncology, 2010, Volume: 12, Issue:10

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carboxymethylcellulose

2010
A multi-institution phase II study of poly-ICLC and radiotherapy with concurrent and adjuvant temozolomide in adults with newly diagnosed glioblastoma.
    Neuro-oncology, 2010, Volume: 12, Issue:10

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carboxymethylcellulose

2010
A multi-institution phase II study of poly-ICLC and radiotherapy with concurrent and adjuvant temozolomide in adults with newly diagnosed glioblastoma.
    Neuro-oncology, 2010, Volume: 12, Issue:10

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carboxymethylcellulose

2010
A multi-institution phase II study of poly-ICLC and radiotherapy with concurrent and adjuvant temozolomide in adults with newly diagnosed glioblastoma.
    Neuro-oncology, 2010, Volume: 12, Issue:10

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carboxymethylcellulose

2010
A multi-institution phase II study of poly-ICLC and radiotherapy with concurrent and adjuvant temozolomide in adults with newly diagnosed glioblastoma.
    Neuro-oncology, 2010, Volume: 12, Issue:10

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carboxymethylcellulose

2010
A multi-institution phase II study of poly-ICLC and radiotherapy with concurrent and adjuvant temozolomide in adults with newly diagnosed glioblastoma.
    Neuro-oncology, 2010, Volume: 12, Issue:10

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carboxymethylcellulose

2010
A multi-institution phase II study of poly-ICLC and radiotherapy with concurrent and adjuvant temozolomide in adults with newly diagnosed glioblastoma.
    Neuro-oncology, 2010, Volume: 12, Issue:10

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carboxymethylcellulose

2010
A multi-institution phase II study of poly-ICLC and radiotherapy with concurrent and adjuvant temozolomide in adults with newly diagnosed glioblastoma.
    Neuro-oncology, 2010, Volume: 12, Issue:10

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carboxymethylcellulose

2010
A multi-institution phase II study of poly-ICLC and radiotherapy with concurrent and adjuvant temozolomide in adults with newly diagnosed glioblastoma.
    Neuro-oncology, 2010, Volume: 12, Issue:10

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carboxymethylcellulose

2010
A multi-institution phase II study of poly-ICLC and radiotherapy with concurrent and adjuvant temozolomide in adults with newly diagnosed glioblastoma.
    Neuro-oncology, 2010, Volume: 12, Issue:10

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carboxymethylcellulose

2010
A multi-institution phase II study of poly-ICLC and radiotherapy with concurrent and adjuvant temozolomide in adults with newly diagnosed glioblastoma.
    Neuro-oncology, 2010, Volume: 12, Issue:10

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carboxymethylcellulose

2010
A multi-institution phase II study of poly-ICLC and radiotherapy with concurrent and adjuvant temozolomide in adults with newly diagnosed glioblastoma.
    Neuro-oncology, 2010, Volume: 12, Issue:10

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carboxymethylcellulose

2010
A multi-institution phase II study of poly-ICLC and radiotherapy with concurrent and adjuvant temozolomide in adults with newly diagnosed glioblastoma.
    Neuro-oncology, 2010, Volume: 12, Issue:10

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carboxymethylcellulose

2010
A multi-institution phase II study of poly-ICLC and radiotherapy with concurrent and adjuvant temozolomide in adults with newly diagnosed glioblastoma.
    Neuro-oncology, 2010, Volume: 12, Issue:10

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carboxymethylcellulose

2010
A multi-institution phase II study of poly-ICLC and radiotherapy with concurrent and adjuvant temozolomide in adults with newly diagnosed glioblastoma.
    Neuro-oncology, 2010, Volume: 12, Issue:10

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carboxymethylcellulose

2010
A multi-institution phase II study of poly-ICLC and radiotherapy with concurrent and adjuvant temozolomide in adults with newly diagnosed glioblastoma.
    Neuro-oncology, 2010, Volume: 12, Issue:10

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carboxymethylcellulose

2010
A multi-institution phase II study of poly-ICLC and radiotherapy with concurrent and adjuvant temozolomide in adults with newly diagnosed glioblastoma.
    Neuro-oncology, 2010, Volume: 12, Issue:10

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carboxymethylcellulose

2010
A multi-institution phase II study of poly-ICLC and radiotherapy with concurrent and adjuvant temozolomide in adults with newly diagnosed glioblastoma.
    Neuro-oncology, 2010, Volume: 12, Issue:10

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carboxymethylcellulose

2010
A multi-institution phase II study of poly-ICLC and radiotherapy with concurrent and adjuvant temozolomide in adults with newly diagnosed glioblastoma.
    Neuro-oncology, 2010, Volume: 12, Issue:10

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carboxymethylcellulose

2010
A multi-institution phase II study of poly-ICLC and radiotherapy with concurrent and adjuvant temozolomide in adults with newly diagnosed glioblastoma.
    Neuro-oncology, 2010, Volume: 12, Issue:10

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carboxymethylcellulose

2010
A multi-institution phase II study of poly-ICLC and radiotherapy with concurrent and adjuvant temozolomide in adults with newly diagnosed glioblastoma.
    Neuro-oncology, 2010, Volume: 12, Issue:10

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carboxymethylcellulose

2010
A multi-institution phase II study of poly-ICLC and radiotherapy with concurrent and adjuvant temozolomide in adults with newly diagnosed glioblastoma.
    Neuro-oncology, 2010, Volume: 12, Issue:10

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carboxymethylcellulose

2010
A multi-institution phase II study of poly-ICLC and radiotherapy with concurrent and adjuvant temozolomide in adults with newly diagnosed glioblastoma.
    Neuro-oncology, 2010, Volume: 12, Issue:10

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carboxymethylcellulose

2010
A multi-institution phase II study of poly-ICLC and radiotherapy with concurrent and adjuvant temozolomide in adults with newly diagnosed glioblastoma.
    Neuro-oncology, 2010, Volume: 12, Issue:10

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carboxymethylcellulose

2010
A multi-institution phase II study of poly-ICLC and radiotherapy with concurrent and adjuvant temozolomide in adults with newly diagnosed glioblastoma.
    Neuro-oncology, 2010, Volume: 12, Issue:10

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carboxymethylcellulose

2010
A multi-institution phase II study of poly-ICLC and radiotherapy with concurrent and adjuvant temozolomide in adults with newly diagnosed glioblastoma.
    Neuro-oncology, 2010, Volume: 12, Issue:10

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carboxymethylcellulose

2010
A multi-institution phase II study of poly-ICLC and radiotherapy with concurrent and adjuvant temozolomide in adults with newly diagnosed glioblastoma.
    Neuro-oncology, 2010, Volume: 12, Issue:10

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carboxymethylcellulose

2010
A multi-institution phase II study of poly-ICLC and radiotherapy with concurrent and adjuvant temozolomide in adults with newly diagnosed glioblastoma.
    Neuro-oncology, 2010, Volume: 12, Issue:10

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carboxymethylcellulose

2010
A multi-institution phase II study of poly-ICLC and radiotherapy with concurrent and adjuvant temozolomide in adults with newly diagnosed glioblastoma.
    Neuro-oncology, 2010, Volume: 12, Issue:10

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carboxymethylcellulose

2010
A multi-institution phase II study of poly-ICLC and radiotherapy with concurrent and adjuvant temozolomide in adults with newly diagnosed glioblastoma.
    Neuro-oncology, 2010, Volume: 12, Issue:10

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carboxymethylcellulose

2010
A multi-institution phase II study of poly-ICLC and radiotherapy with concurrent and adjuvant temozolomide in adults with newly diagnosed glioblastoma.
    Neuro-oncology, 2010, Volume: 12, Issue:10

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carboxymethylcellulose

2010
A multi-institution phase II study of poly-ICLC and radiotherapy with concurrent and adjuvant temozolomide in adults with newly diagnosed glioblastoma.
    Neuro-oncology, 2010, Volume: 12, Issue:10

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carboxymethylcellulose

2010
A multi-institution phase II study of poly-ICLC and radiotherapy with concurrent and adjuvant temozolomide in adults with newly diagnosed glioblastoma.
    Neuro-oncology, 2010, Volume: 12, Issue:10

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carboxymethylcellulose

2010
A multi-institution phase II study of poly-ICLC and radiotherapy with concurrent and adjuvant temozolomide in adults with newly diagnosed glioblastoma.
    Neuro-oncology, 2010, Volume: 12, Issue:10

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carboxymethylcellulose

2010
A multi-institution phase II study of poly-ICLC and radiotherapy with concurrent and adjuvant temozolomide in adults with newly diagnosed glioblastoma.
    Neuro-oncology, 2010, Volume: 12, Issue:10

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carboxymethylcellulose

2010
A multi-institution phase II study of poly-ICLC and radiotherapy with concurrent and adjuvant temozolomide in adults with newly diagnosed glioblastoma.
    Neuro-oncology, 2010, Volume: 12, Issue:10

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carboxymethylcellulose

2010
A multi-institution phase II study of poly-ICLC and radiotherapy with concurrent and adjuvant temozolomide in adults with newly diagnosed glioblastoma.
    Neuro-oncology, 2010, Volume: 12, Issue:10

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carboxymethylcellulose

2010
A multi-institution phase II study of poly-ICLC and radiotherapy with concurrent and adjuvant temozolomide in adults with newly diagnosed glioblastoma.
    Neuro-oncology, 2010, Volume: 12, Issue:10

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carboxymethylcellulose

2010
A multi-institution phase II study of poly-ICLC and radiotherapy with concurrent and adjuvant temozolomide in adults with newly diagnosed glioblastoma.
    Neuro-oncology, 2010, Volume: 12, Issue:10

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carboxymethylcellulose

2010
A multi-institution phase II study of poly-ICLC and radiotherapy with concurrent and adjuvant temozolomide in adults with newly diagnosed glioblastoma.
    Neuro-oncology, 2010, Volume: 12, Issue:10

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carboxymethylcellulose

2010
A multi-institution phase II study of poly-ICLC and radiotherapy with concurrent and adjuvant temozolomide in adults with newly diagnosed glioblastoma.
    Neuro-oncology, 2010, Volume: 12, Issue:10

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carboxymethylcellulose

2010
A multi-institution phase II study of poly-ICLC and radiotherapy with concurrent and adjuvant temozolomide in adults with newly diagnosed glioblastoma.
    Neuro-oncology, 2010, Volume: 12, Issue:10

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carboxymethylcellulose

2010
A multi-institution phase II study of poly-ICLC and radiotherapy with concurrent and adjuvant temozolomide in adults with newly diagnosed glioblastoma.
    Neuro-oncology, 2010, Volume: 12, Issue:10

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carboxymethylcellulose

2010
A multi-institution phase II study of poly-ICLC and radiotherapy with concurrent and adjuvant temozolomide in adults with newly diagnosed glioblastoma.
    Neuro-oncology, 2010, Volume: 12, Issue:10

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carboxymethylcellulose

2010
A multi-institution phase II study of poly-ICLC and radiotherapy with concurrent and adjuvant temozolomide in adults with newly diagnosed glioblastoma.
    Neuro-oncology, 2010, Volume: 12, Issue:10

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carboxymethylcellulose

2010
A multi-institution phase II study of poly-ICLC and radiotherapy with concurrent and adjuvant temozolomide in adults with newly diagnosed glioblastoma.
    Neuro-oncology, 2010, Volume: 12, Issue:10

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carboxymethylcellulose

2010
A multi-institution phase II study of poly-ICLC and radiotherapy with concurrent and adjuvant temozolomide in adults with newly diagnosed glioblastoma.
    Neuro-oncology, 2010, Volume: 12, Issue:10

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carboxymethylcellulose

2010
A multi-institution phase II study of poly-ICLC and radiotherapy with concurrent and adjuvant temozolomide in adults with newly diagnosed glioblastoma.
    Neuro-oncology, 2010, Volume: 12, Issue:10

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carboxymethylcellulose

2010
A multi-institution phase II study of poly-ICLC and radiotherapy with concurrent and adjuvant temozolomide in adults with newly diagnosed glioblastoma.
    Neuro-oncology, 2010, Volume: 12, Issue:10

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carboxymethylcellulose

2010
A multi-institution phase II study of poly-ICLC and radiotherapy with concurrent and adjuvant temozolomide in adults with newly diagnosed glioblastoma.
    Neuro-oncology, 2010, Volume: 12, Issue:10

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carboxymethylcellulose

2010
A multi-institution phase II study of poly-ICLC and radiotherapy with concurrent and adjuvant temozolomide in adults with newly diagnosed glioblastoma.
    Neuro-oncology, 2010, Volume: 12, Issue:10

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carboxymethylcellulose

2010
A multi-institution phase II study of poly-ICLC and radiotherapy with concurrent and adjuvant temozolomide in adults with newly diagnosed glioblastoma.
    Neuro-oncology, 2010, Volume: 12, Issue:10

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carboxymethylcellulose

2010
A new schedule of fotemustine in temozolomide-pretreated patients with relapsing glioblastoma.
    Journal of neuro-oncology, 2011, Volume: 102, Issue:3

    Topics: Adult; Aged; Antineoplastic Agents; Brain Neoplasms; Confidence Intervals; Dacarbazine; Disease-Free

2011
A new schedule of fotemustine in temozolomide-pretreated patients with relapsing glioblastoma.
    Journal of neuro-oncology, 2011, Volume: 102, Issue:3

    Topics: Adult; Aged; Antineoplastic Agents; Brain Neoplasms; Confidence Intervals; Dacarbazine; Disease-Free

2011
A new schedule of fotemustine in temozolomide-pretreated patients with relapsing glioblastoma.
    Journal of neuro-oncology, 2011, Volume: 102, Issue:3

    Topics: Adult; Aged; Antineoplastic Agents; Brain Neoplasms; Confidence Intervals; Dacarbazine; Disease-Free

2011
Impact of adjuvant chemotherapy for gliomatosis cerebri.
    BMC cancer, 2010, Aug-13, Volume: 10

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carmustine

2010
Impact of adjuvant chemotherapy for gliomatosis cerebri.
    BMC cancer, 2010, Aug-13, Volume: 10

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carmustine

2010
Impact of adjuvant chemotherapy for gliomatosis cerebri.
    BMC cancer, 2010, Aug-13, Volume: 10

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carmustine

2010
Randomized phase II study evaluating a carbon ion boost applied after combined radiochemotherapy with temozolomide versus a proton boost after radiochemotherapy with temozolomide in patients with primary glioblastoma: the CLEOPATRA trial.
    BMC cancer, 2010, Sep-06, Volume: 10

    Topics: Adolescent; Antineoplastic Agents, Alkylating; Brain Neoplasms; Carbon; Combined Modality Therapy; D

2010
Randomized phase II study evaluating a carbon ion boost applied after combined radiochemotherapy with temozolomide versus a proton boost after radiochemotherapy with temozolomide in patients with primary glioblastoma: the CLEOPATRA trial.
    BMC cancer, 2010, Sep-06, Volume: 10

    Topics: Adolescent; Antineoplastic Agents, Alkylating; Brain Neoplasms; Carbon; Combined Modality Therapy; D

2010
Randomized phase II study evaluating a carbon ion boost applied after combined radiochemotherapy with temozolomide versus a proton boost after radiochemotherapy with temozolomide in patients with primary glioblastoma: the CLEOPATRA trial.
    BMC cancer, 2010, Sep-06, Volume: 10

    Topics: Adolescent; Antineoplastic Agents, Alkylating; Brain Neoplasms; Carbon; Combined Modality Therapy; D

2010
Phase I trial with biomarker studies of vatalanib (PTK787) in patients with newly diagnosed glioblastoma treated with enzyme inducing anti-epileptic drugs and standard radiation and temozolomide.
    Journal of neuro-oncology, 2011, Volume: 103, Issue:2

    Topics: Adult; Aged; Anticonvulsants; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols;

2011
Phase I trial with biomarker studies of vatalanib (PTK787) in patients with newly diagnosed glioblastoma treated with enzyme inducing anti-epileptic drugs and standard radiation and temozolomide.
    Journal of neuro-oncology, 2011, Volume: 103, Issue:2

    Topics: Adult; Aged; Anticonvulsants; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols;

2011
Phase I trial with biomarker studies of vatalanib (PTK787) in patients with newly diagnosed glioblastoma treated with enzyme inducing anti-epileptic drugs and standard radiation and temozolomide.
    Journal of neuro-oncology, 2011, Volume: 103, Issue:2

    Topics: Adult; Aged; Anticonvulsants; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols;

2011
Phase II study of metronomic chemotherapy with bevacizumab for recurrent glioblastoma after progression on bevacizumab therapy.
    Journal of neuro-oncology, 2011, Volume: 103, Issue:2

    Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Prot

2011
Phase II study of metronomic chemotherapy with bevacizumab for recurrent glioblastoma after progression on bevacizumab therapy.
    Journal of neuro-oncology, 2011, Volume: 103, Issue:2

    Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Prot

2011
Phase II study of metronomic chemotherapy with bevacizumab for recurrent glioblastoma after progression on bevacizumab therapy.
    Journal of neuro-oncology, 2011, Volume: 103, Issue:2

    Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Prot

2011
North Central Cancer Treatment Group Phase I trial N057K of everolimus (RAD001) and temozolomide in combination with radiation therapy in patients with newly diagnosed glioblastoma multiforme.
    International journal of radiation oncology, biology, physics, 2011, Oct-01, Volume: 81, Issue:2

    Topics: Administration, Oral; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms;

2011
North Central Cancer Treatment Group Phase I trial N057K of everolimus (RAD001) and temozolomide in combination with radiation therapy in patients with newly diagnosed glioblastoma multiforme.
    International journal of radiation oncology, biology, physics, 2011, Oct-01, Volume: 81, Issue:2

    Topics: Administration, Oral; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms;

2011
North Central Cancer Treatment Group Phase I trial N057K of everolimus (RAD001) and temozolomide in combination with radiation therapy in patients with newly diagnosed glioblastoma multiforme.
    International journal of radiation oncology, biology, physics, 2011, Oct-01, Volume: 81, Issue:2

    Topics: Administration, Oral; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms;

2011
Immunologic escape after prolonged progression-free survival with epidermal growth factor receptor variant III peptide vaccination in patients with newly diagnosed glioblastoma.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2010, Nov-01, Volume: 28, Issue:31

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cancer Vaccines; Chemotherapy, Adju

2010
Immunologic escape after prolonged progression-free survival with epidermal growth factor receptor variant III peptide vaccination in patients with newly diagnosed glioblastoma.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2010, Nov-01, Volume: 28, Issue:31

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cancer Vaccines; Chemotherapy, Adju

2010
Immunologic escape after prolonged progression-free survival with epidermal growth factor receptor variant III peptide vaccination in patients with newly diagnosed glioblastoma.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2010, Nov-01, Volume: 28, Issue:31

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cancer Vaccines; Chemotherapy, Adju

2010
Favorable outcome in the elderly cohort treated by concomitant temozolomide radiochemotherapy in a multicentric phase II safety study of 5-ALA.
    Journal of neuro-oncology, 2011, Volume: 103, Issue:2

    Topics: Aged; Aged, 80 and over; Aminolevulinic Acid; Antineoplastic Agents; Brain Neoplasms; Combined Modal

2011
Favorable outcome in the elderly cohort treated by concomitant temozolomide radiochemotherapy in a multicentric phase II safety study of 5-ALA.
    Journal of neuro-oncology, 2011, Volume: 103, Issue:2

    Topics: Aged; Aged, 80 and over; Aminolevulinic Acid; Antineoplastic Agents; Brain Neoplasms; Combined Modal

2011
Favorable outcome in the elderly cohort treated by concomitant temozolomide radiochemotherapy in a multicentric phase II safety study of 5-ALA.
    Journal of neuro-oncology, 2011, Volume: 103, Issue:2

    Topics: Aged; Aged, 80 and over; Aminolevulinic Acid; Antineoplastic Agents; Brain Neoplasms; Combined Modal

2011
Phase I trial of hypofractionated intensity-modulated radiotherapy with temozolomide chemotherapy for patients with newly diagnosed glioblastoma multiforme.
    International journal of radiation oncology, biology, physics, 2011, Nov-15, Volume: 81, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherap

2011
Phase I trial of hypofractionated intensity-modulated radiotherapy with temozolomide chemotherapy for patients with newly diagnosed glioblastoma multiforme.
    International journal of radiation oncology, biology, physics, 2011, Nov-15, Volume: 81, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherap

2011
Phase I trial of hypofractionated intensity-modulated radiotherapy with temozolomide chemotherapy for patients with newly diagnosed glioblastoma multiforme.
    International journal of radiation oncology, biology, physics, 2011, Nov-15, Volume: 81, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherap

2011
A phase I trial of tipifarnib with radiation therapy, with and without temozolomide, for patients with newly diagnosed glioblastoma.
    International journal of radiation oncology, biology, physics, 2011, Dec-01, Volume: 81, Issue:5

    Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms;

2011
A phase I trial of tipifarnib with radiation therapy, with and without temozolomide, for patients with newly diagnosed glioblastoma.
    International journal of radiation oncology, biology, physics, 2011, Dec-01, Volume: 81, Issue:5

    Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms;

2011
A phase I trial of tipifarnib with radiation therapy, with and without temozolomide, for patients with newly diagnosed glioblastoma.
    International journal of radiation oncology, biology, physics, 2011, Dec-01, Volume: 81, Issue:5

    Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms;

2011
Phase I dose escalation trial of vandetanib with fractionated radiosurgery in patients with recurrent malignant gliomas.
    International journal of radiation oncology, biology, physics, 2012, Jan-01, Volume: 82, Issue:1

    Topics: Administration, Oral; Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Proto

2012
Phase I dose escalation trial of vandetanib with fractionated radiosurgery in patients with recurrent malignant gliomas.
    International journal of radiation oncology, biology, physics, 2012, Jan-01, Volume: 82, Issue:1

    Topics: Administration, Oral; Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Proto

2012
Phase I dose escalation trial of vandetanib with fractionated radiosurgery in patients with recurrent malignant gliomas.
    International journal of radiation oncology, biology, physics, 2012, Jan-01, Volume: 82, Issue:1

    Topics: Administration, Oral; Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Proto

2012
Addition of bevacizumab to standard radiation therapy and daily temozolomide is associated with minimal toxicity in newly diagnosed glioblastoma multiforme.
    International journal of radiation oncology, biology, physics, 2012, Jan-01, Volume: 82, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Antineop

2012
Addition of bevacizumab to standard radiation therapy and daily temozolomide is associated with minimal toxicity in newly diagnosed glioblastoma multiforme.
    International journal of radiation oncology, biology, physics, 2012, Jan-01, Volume: 82, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Antineop

2012
Addition of bevacizumab to standard radiation therapy and daily temozolomide is associated with minimal toxicity in newly diagnosed glioblastoma multiforme.
    International journal of radiation oncology, biology, physics, 2012, Jan-01, Volume: 82, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Antineop

2012
The outcomes of concomitant radiation plus temozolomide followed by adjuvant temozolomide for newly diagnosed high grade gliomas: the preliminary results of single center prospective study.
    Journal of the Egyptian National Cancer Institute, 2009, Volume: 21, Issue:2

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neoplasms; Chemotherapy, Adjuvant

2009
The outcomes of concomitant radiation plus temozolomide followed by adjuvant temozolomide for newly diagnosed high grade gliomas: the preliminary results of single center prospective study.
    Journal of the Egyptian National Cancer Institute, 2009, Volume: 21, Issue:2

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neoplasms; Chemotherapy, Adjuvant

2009
The outcomes of concomitant radiation plus temozolomide followed by adjuvant temozolomide for newly diagnosed high grade gliomas: the preliminary results of single center prospective study.
    Journal of the Egyptian National Cancer Institute, 2009, Volume: 21, Issue:2

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neoplasms; Chemotherapy, Adjuvant

2009
Phase II study of bevacizumab plus temozolomide during and after radiation therapy for patients with newly diagnosed glioblastoma multiforme.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2011, Jan-10, Volume: 29, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclo

2011
Phase II study of bevacizumab plus temozolomide during and after radiation therapy for patients with newly diagnosed glioblastoma multiforme.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2011, Jan-10, Volume: 29, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclo

2011
Phase II study of bevacizumab plus temozolomide during and after radiation therapy for patients with newly diagnosed glioblastoma multiforme.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2011, Jan-10, Volume: 29, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclo

2011
Greater chemotherapy-induced lymphopenia enhances tumor-specific immune responses that eliminate EGFRvIII-expressing tumor cells in patients with glioblastoma.
    Neuro-oncology, 2011, Volume: 13, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Ad

2011
Greater chemotherapy-induced lymphopenia enhances tumor-specific immune responses that eliminate EGFRvIII-expressing tumor cells in patients with glioblastoma.
    Neuro-oncology, 2011, Volume: 13, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Ad

2011
Greater chemotherapy-induced lymphopenia enhances tumor-specific immune responses that eliminate EGFRvIII-expressing tumor cells in patients with glioblastoma.
    Neuro-oncology, 2011, Volume: 13, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Ad

2011
A multicenter phase I trial of combination therapy with interferon-β and temozolomide for high-grade gliomas (INTEGRA study): the final report.
    Journal of neuro-oncology, 2011, Volume: 104, Issue:2

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Dacarbazine; Disease-F

2011
A multicenter phase I trial of combination therapy with interferon-β and temozolomide for high-grade gliomas (INTEGRA study): the final report.
    Journal of neuro-oncology, 2011, Volume: 104, Issue:2

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Dacarbazine; Disease-F

2011
A multicenter phase I trial of combination therapy with interferon-β and temozolomide for high-grade gliomas (INTEGRA study): the final report.
    Journal of neuro-oncology, 2011, Volume: 104, Issue:2

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Dacarbazine; Disease-F

2011
Temozolomide in the treatment of high-grade gliomas in children: a report from the Children's Oncology Group.
    Neuro-oncology, 2011, Volume: 13, Issue:3

    Topics: Adolescent; Adult; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant; Child

2011
Temozolomide in the treatment of high-grade gliomas in children: a report from the Children's Oncology Group.
    Neuro-oncology, 2011, Volume: 13, Issue:3

    Topics: Adolescent; Adult; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant; Child

2011
Temozolomide in the treatment of high-grade gliomas in children: a report from the Children's Oncology Group.
    Neuro-oncology, 2011, Volume: 13, Issue:3

    Topics: Adolescent; Adult; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant; Child

2011
Phase I clinical trial assessing temozolomide and tamoxifen with concomitant radiotherapy for treatment of high-grade glioma.
    International journal of radiation oncology, biology, physics, 2012, Feb-01, Volume: 82, Issue:2

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Chemoradio

2012
Phase I clinical trial assessing temozolomide and tamoxifen with concomitant radiotherapy for treatment of high-grade glioma.
    International journal of radiation oncology, biology, physics, 2012, Feb-01, Volume: 82, Issue:2

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Chemoradio

2012
Phase I clinical trial assessing temozolomide and tamoxifen with concomitant radiotherapy for treatment of high-grade glioma.
    International journal of radiation oncology, biology, physics, 2012, Feb-01, Volume: 82, Issue:2

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Chemoradio

2012
Temozolomide and 13-cis retinoic acid in patients with anaplastic gliomas: a prospective single-arm monocentric phase-II study (RNOP-05).
    Journal of neuro-oncology, 2011, Volume: 104, Issue:3

    Topics: Administration, Oral; Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Brain Neopl

2011
Temozolomide and 13-cis retinoic acid in patients with anaplastic gliomas: a prospective single-arm monocentric phase-II study (RNOP-05).
    Journal of neuro-oncology, 2011, Volume: 104, Issue:3

    Topics: Administration, Oral; Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Brain Neopl

2011
Temozolomide and 13-cis retinoic acid in patients with anaplastic gliomas: a prospective single-arm monocentric phase-II study (RNOP-05).
    Journal of neuro-oncology, 2011, Volume: 104, Issue:3

    Topics: Administration, Oral; Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Brain Neopl

2011
Patterns of failure for glioblastoma multiforme following concurrent radiation and temozolomide.
    Journal of medical imaging and radiation oncology, 2011, Volume: 55, Issue:1

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbaz

2011
Patterns of failure for glioblastoma multiforme following concurrent radiation and temozolomide.
    Journal of medical imaging and radiation oncology, 2011, Volume: 55, Issue:1

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbaz

2011
Patterns of failure for glioblastoma multiforme following concurrent radiation and temozolomide.
    Journal of medical imaging and radiation oncology, 2011, Volume: 55, Issue:1

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbaz

2011
AVAglio: Phase 3 trial of bevacizumab plus temozolomide and radiotherapy in newly diagnosed glioblastoma multiforme.
    Advances in therapy, 2011, Volume: 28, Issue:4

    Topics: Adult; Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineopl

2011
AVAglio: Phase 3 trial of bevacizumab plus temozolomide and radiotherapy in newly diagnosed glioblastoma multiforme.
    Advances in therapy, 2011, Volume: 28, Issue:4

    Topics: Adult; Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineopl

2011
AVAglio: Phase 3 trial of bevacizumab plus temozolomide and radiotherapy in newly diagnosed glioblastoma multiforme.
    Advances in therapy, 2011, Volume: 28, Issue:4

    Topics: Adult; Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineopl

2011
Phase II clinical study of boron neutron capture therapy combined with X-ray radiotherapy/temozolomide in patients with newly diagnosed glioblastoma multiforme--study design and current status report.
    Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine, 2011, Volume: 69, Issue:12

    Topics: Antineoplastic Agents; Boron Neutron Capture Therapy; Brain Neoplasms; Combined Modality Therapy; Da

2011
Phase II clinical study of boron neutron capture therapy combined with X-ray radiotherapy/temozolomide in patients with newly diagnosed glioblastoma multiforme--study design and current status report.
    Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine, 2011, Volume: 69, Issue:12

    Topics: Antineoplastic Agents; Boron Neutron Capture Therapy; Brain Neoplasms; Combined Modality Therapy; Da

2011
Phase II clinical study of boron neutron capture therapy combined with X-ray radiotherapy/temozolomide in patients with newly diagnosed glioblastoma multiforme--study design and current status report.
    Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine, 2011, Volume: 69, Issue:12

    Topics: Antineoplastic Agents; Boron Neutron Capture Therapy; Brain Neoplasms; Combined Modality Therapy; Da

2011
Prognostic impact of CD133 mRNA expression in 48 glioblastoma patients treated with concomitant radiochemotherapy: a prospective patient cohort at a single institution.
    Annals of surgical oncology, 2011, Volume: 18, Issue:10

    Topics: AC133 Antigen; Adult; Aged; Antigens, CD; Antineoplastic Agents, Alkylating; Biomarkers, Tumor; Brai

2011
Prognostic impact of CD133 mRNA expression in 48 glioblastoma patients treated with concomitant radiochemotherapy: a prospective patient cohort at a single institution.
    Annals of surgical oncology, 2011, Volume: 18, Issue:10

    Topics: AC133 Antigen; Adult; Aged; Antigens, CD; Antineoplastic Agents, Alkylating; Biomarkers, Tumor; Brai

2011
Prognostic impact of CD133 mRNA expression in 48 glioblastoma patients treated with concomitant radiochemotherapy: a prospective patient cohort at a single institution.
    Annals of surgical oncology, 2011, Volume: 18, Issue:10

    Topics: AC133 Antigen; Adult; Aged; Antigens, CD; Antineoplastic Agents, Alkylating; Biomarkers, Tumor; Brai

2011
Phase II study of aflibercept in recurrent malignant glioma: a North American Brain Tumor Consortium study.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2011, Jul-01, Volume: 29, Issue:19

    Topics: Adult; Aged; Antineoplastic Agents; Brain Neoplasms; Chemotherapy, Adjuvant; Cohort Studies; Dacarba

2011
Phase II study of aflibercept in recurrent malignant glioma: a North American Brain Tumor Consortium study.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2011, Jul-01, Volume: 29, Issue:19

    Topics: Adult; Aged; Antineoplastic Agents; Brain Neoplasms; Chemotherapy, Adjuvant; Cohort Studies; Dacarba

2011
Phase II study of aflibercept in recurrent malignant glioma: a North American Brain Tumor Consortium study.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2011, Jul-01, Volume: 29, Issue:19

    Topics: Adult; Aged; Antineoplastic Agents; Brain Neoplasms; Chemotherapy, Adjuvant; Cohort Studies; Dacarba

2011
Central nervous system failure in melanoma patients: results of a randomised, multicentre phase 3 study of temozolomide- and dacarbazine- based regimens.
    British journal of cancer, 2011, Jun-07, Volume: 104, Issue:12

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Blood-Brain Barrier; Brain Neoplasms; D

2011
Central nervous system failure in melanoma patients: results of a randomised, multicentre phase 3 study of temozolomide- and dacarbazine- based regimens.
    British journal of cancer, 2011, Jun-07, Volume: 104, Issue:12

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Blood-Brain Barrier; Brain Neoplasms; D

2011
Central nervous system failure in melanoma patients: results of a randomised, multicentre phase 3 study of temozolomide- and dacarbazine- based regimens.
    British journal of cancer, 2011, Jun-07, Volume: 104, Issue:12

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Blood-Brain Barrier; Brain Neoplasms; D

2011
Temozolomide in elderly patients with newly diagnosed glioblastoma and poor performance status: an ANOCEF phase II trial.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2011, Aug-01, Volume: 29, Issue:22

    Topics: Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cognition; Dacarbazine;

2011
Temozolomide in elderly patients with newly diagnosed glioblastoma and poor performance status: an ANOCEF phase II trial.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2011, Aug-01, Volume: 29, Issue:22

    Topics: Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cognition; Dacarbazine;

2011
Temozolomide in elderly patients with newly diagnosed glioblastoma and poor performance status: an ANOCEF phase II trial.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2011, Aug-01, Volume: 29, Issue:22

    Topics: Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cognition; Dacarbazine;

2011
A phase I trial of the farnesyl transferase inhibitor, SCH 66336, with temozolomide for patients with malignant glioma.
    Journal of neuro-oncology, 2011, Volume: 105, Issue:3

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carotenoids; Dacarbazi

2011
A phase I trial of the farnesyl transferase inhibitor, SCH 66336, with temozolomide for patients with malignant glioma.
    Journal of neuro-oncology, 2011, Volume: 105, Issue:3

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carotenoids; Dacarbazi

2011
A phase I trial of the farnesyl transferase inhibitor, SCH 66336, with temozolomide for patients with malignant glioma.
    Journal of neuro-oncology, 2011, Volume: 105, Issue:3

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carotenoids; Dacarbazi

2011
MRI and thallium-201 SPECT in the prediction of survival in glioma.
    Neuroradiology, 2012, Volume: 54, Issue:6

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Female; Gl

2012
MRI and thallium-201 SPECT in the prediction of survival in glioma.
    Neuroradiology, 2012, Volume: 54, Issue:6

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Female; Gl

2012
MRI and thallium-201 SPECT in the prediction of survival in glioma.
    Neuroradiology, 2012, Volume: 54, Issue:6

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Female; Gl

2012
Monoclonal antibody blockade of IL-2 receptor α during lymphopenia selectively depletes regulatory T cells in mice and humans.
    Blood, 2011, Sep-15, Volume: 118, Issue:11

    Topics: Adult; Animals; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents, Al

2011
Monoclonal antibody blockade of IL-2 receptor α during lymphopenia selectively depletes regulatory T cells in mice and humans.
    Blood, 2011, Sep-15, Volume: 118, Issue:11

    Topics: Adult; Animals; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents, Al

2011
Monoclonal antibody blockade of IL-2 receptor α during lymphopenia selectively depletes regulatory T cells in mice and humans.
    Blood, 2011, Sep-15, Volume: 118, Issue:11

    Topics: Adult; Animals; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents, Al

2011
Bevacizumab and daily temozolomide for recurrent glioblastoma.
    Cancer, 2012, Mar-01, Volume: 118, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemother

2012
Bevacizumab and daily temozolomide for recurrent glioblastoma.
    Cancer, 2012, Mar-01, Volume: 118, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemother

2012
Bevacizumab and daily temozolomide for recurrent glioblastoma.
    Cancer, 2012, Mar-01, Volume: 118, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemother

2012
Phase 2 trial of temozolomide and pegylated liposomal doxorubicin in the treatment of patients with glioblastoma multiforme following concurrent radiotherapy and chemotherapy.
    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2011, Volume: 18, Issue:11

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Dacarbazine; Disease-F

2011
Phase 2 trial of temozolomide and pegylated liposomal doxorubicin in the treatment of patients with glioblastoma multiforme following concurrent radiotherapy and chemotherapy.
    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2011, Volume: 18, Issue:11

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Dacarbazine; Disease-F

2011
Phase 2 trial of temozolomide and pegylated liposomal doxorubicin in the treatment of patients with glioblastoma multiforme following concurrent radiotherapy and chemotherapy.
    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2011, Volume: 18, Issue:11

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Dacarbazine; Disease-F

2011
Phase IB study of gene-mediated cytotoxic immunotherapy adjuvant to up-front surgery and intensive timing radiation for malignant glioma.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2011, Sep-20, Volume: 29, Issue:27

    Topics: Acyclovir; Adenoviridae; Adjuvants, Immunologic; Adult; Aged; Antineoplastic Agents, Alkylating; Ant

2011
Phase IB study of gene-mediated cytotoxic immunotherapy adjuvant to up-front surgery and intensive timing radiation for malignant glioma.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2011, Sep-20, Volume: 29, Issue:27

    Topics: Acyclovir; Adenoviridae; Adjuvants, Immunologic; Adult; Aged; Antineoplastic Agents, Alkylating; Ant

2011
Phase IB study of gene-mediated cytotoxic immunotherapy adjuvant to up-front surgery and intensive timing radiation for malignant glioma.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2011, Sep-20, Volume: 29, Issue:27

    Topics: Acyclovir; Adenoviridae; Adjuvants, Immunologic; Adult; Aged; Antineoplastic Agents, Alkylating; Ant

2011
Prolonged survival with valproic acid use in the EORTC/NCIC temozolomide trial for glioblastoma.
    Neurology, 2011, Sep-20, Volume: 77, Issue:12

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Dacarbazine; Eu

2011
Prolonged survival with valproic acid use in the EORTC/NCIC temozolomide trial for glioblastoma.
    Neurology, 2011, Sep-20, Volume: 77, Issue:12

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Dacarbazine; Eu

2011
Prolonged survival with valproic acid use in the EORTC/NCIC temozolomide trial for glioblastoma.
    Neurology, 2011, Sep-20, Volume: 77, Issue:12

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Dacarbazine; Eu

2011
Prolonged survival with valproic acid use in the EORTC/NCIC temozolomide trial for glioblastoma.
    Neurology, 2011, Sep-20, Volume: 77, Issue:12

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Dacarbazine; Eu

2011
Prolonged survival with valproic acid use in the EORTC/NCIC temozolomide trial for glioblastoma.
    Neurology, 2011, Sep-20, Volume: 77, Issue:12

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Dacarbazine; Eu

2011
Prolonged survival with valproic acid use in the EORTC/NCIC temozolomide trial for glioblastoma.
    Neurology, 2011, Sep-20, Volume: 77, Issue:12

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Dacarbazine; Eu

2011
Prolonged survival with valproic acid use in the EORTC/NCIC temozolomide trial for glioblastoma.
    Neurology, 2011, Sep-20, Volume: 77, Issue:12

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Dacarbazine; Eu

2011
Prolonged survival with valproic acid use in the EORTC/NCIC temozolomide trial for glioblastoma.
    Neurology, 2011, Sep-20, Volume: 77, Issue:12

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Dacarbazine; Eu

2011
Prolonged survival with valproic acid use in the EORTC/NCIC temozolomide trial for glioblastoma.
    Neurology, 2011, Sep-20, Volume: 77, Issue:12

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Dacarbazine; Eu

2011
Prolonged survival with valproic acid use in the EORTC/NCIC temozolomide trial for glioblastoma.
    Neurology, 2011, Sep-20, Volume: 77, Issue:12

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Dacarbazine; Eu

2011
Prolonged survival with valproic acid use in the EORTC/NCIC temozolomide trial for glioblastoma.
    Neurology, 2011, Sep-20, Volume: 77, Issue:12

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Dacarbazine; Eu

2011
Prolonged survival with valproic acid use in the EORTC/NCIC temozolomide trial for glioblastoma.
    Neurology, 2011, Sep-20, Volume: 77, Issue:12

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Dacarbazine; Eu

2011
Prolonged survival with valproic acid use in the EORTC/NCIC temozolomide trial for glioblastoma.
    Neurology, 2011, Sep-20, Volume: 77, Issue:12

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Dacarbazine; Eu

2011
Prolonged survival with valproic acid use in the EORTC/NCIC temozolomide trial for glioblastoma.
    Neurology, 2011, Sep-20, Volume: 77, Issue:12

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Dacarbazine; Eu

2011
Prolonged survival with valproic acid use in the EORTC/NCIC temozolomide trial for glioblastoma.
    Neurology, 2011, Sep-20, Volume: 77, Issue:12

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Dacarbazine; Eu

2011
Prolonged survival with valproic acid use in the EORTC/NCIC temozolomide trial for glioblastoma.
    Neurology, 2011, Sep-20, Volume: 77, Issue:12

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Dacarbazine; Eu

2011
Prolonged survival with valproic acid use in the EORTC/NCIC temozolomide trial for glioblastoma.
    Neurology, 2011, Sep-20, Volume: 77, Issue:12

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Dacarbazine; Eu

2011
Prolonged survival with valproic acid use in the EORTC/NCIC temozolomide trial for glioblastoma.
    Neurology, 2011, Sep-20, Volume: 77, Issue:12

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Dacarbazine; Eu

2011
Prolonged survival with valproic acid use in the EORTC/NCIC temozolomide trial for glioblastoma.
    Neurology, 2011, Sep-20, Volume: 77, Issue:12

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Dacarbazine; Eu

2011
Prolonged survival with valproic acid use in the EORTC/NCIC temozolomide trial for glioblastoma.
    Neurology, 2011, Sep-20, Volume: 77, Issue:12

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Dacarbazine; Eu

2011
Prolonged survival with valproic acid use in the EORTC/NCIC temozolomide trial for glioblastoma.
    Neurology, 2011, Sep-20, Volume: 77, Issue:12

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Dacarbazine; Eu

2011
Prolonged survival with valproic acid use in the EORTC/NCIC temozolomide trial for glioblastoma.
    Neurology, 2011, Sep-20, Volume: 77, Issue:12

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Dacarbazine; Eu

2011
Prolonged survival with valproic acid use in the EORTC/NCIC temozolomide trial for glioblastoma.
    Neurology, 2011, Sep-20, Volume: 77, Issue:12

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Dacarbazine; Eu

2011
Prolonged survival with valproic acid use in the EORTC/NCIC temozolomide trial for glioblastoma.
    Neurology, 2011, Sep-20, Volume: 77, Issue:12

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Dacarbazine; Eu

2011
Prolonged survival with valproic acid use in the EORTC/NCIC temozolomide trial for glioblastoma.
    Neurology, 2011, Sep-20, Volume: 77, Issue:12

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Dacarbazine; Eu

2011
Prolonged survival with valproic acid use in the EORTC/NCIC temozolomide trial for glioblastoma.
    Neurology, 2011, Sep-20, Volume: 77, Issue:12

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Dacarbazine; Eu

2011
Prolonged survival with valproic acid use in the EORTC/NCIC temozolomide trial for glioblastoma.
    Neurology, 2011, Sep-20, Volume: 77, Issue:12

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Dacarbazine; Eu

2011
Phase II and pharmacogenomics study of enzastaurin plus temozolomide during and following radiation therapy in patients with newly diagnosed glioblastoma multiforme and gliosarcoma.
    Neuro-oncology, 2011, Volume: 13, Issue:12

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Brain; Brain Neoplas

2011
Phase II and pharmacogenomics study of enzastaurin plus temozolomide during and following radiation therapy in patients with newly diagnosed glioblastoma multiforme and gliosarcoma.
    Neuro-oncology, 2011, Volume: 13, Issue:12

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Brain; Brain Neoplas

2011
Phase II and pharmacogenomics study of enzastaurin plus temozolomide during and following radiation therapy in patients with newly diagnosed glioblastoma multiforme and gliosarcoma.
    Neuro-oncology, 2011, Volume: 13, Issue:12

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Brain; Brain Neoplas

2011
Efficacy and toxicity of CyberKnife re-irradiation and "dose dense" temozolomide for recurrent gliomas.
    Acta neurochirurgica, 2012, Volume: 154, Issue:2

    Topics: Antineoplastic Agents, Alkylating; Asthenia; Brain Neoplasms; Dacarbazine; Disease-Free Survival; Fe

2012
Efficacy and toxicity of CyberKnife re-irradiation and "dose dense" temozolomide for recurrent gliomas.
    Acta neurochirurgica, 2012, Volume: 154, Issue:2

    Topics: Antineoplastic Agents, Alkylating; Asthenia; Brain Neoplasms; Dacarbazine; Disease-Free Survival; Fe

2012
Efficacy and toxicity of CyberKnife re-irradiation and "dose dense" temozolomide for recurrent gliomas.
    Acta neurochirurgica, 2012, Volume: 154, Issue:2

    Topics: Antineoplastic Agents, Alkylating; Asthenia; Brain Neoplasms; Dacarbazine; Disease-Free Survival; Fe

2012
Prognostic factors and survival in a prospective cohort of patients with high-grade glioma treated with carmustine wafers or temozolomide on an intention-to-treat basis.
    Acta neurochirurgica, 2012, Volume: 154, Issue:2

    Topics: Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms;

2012
Prognostic factors and survival in a prospective cohort of patients with high-grade glioma treated with carmustine wafers or temozolomide on an intention-to-treat basis.
    Acta neurochirurgica, 2012, Volume: 154, Issue:2

    Topics: Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms;

2012
Prognostic factors and survival in a prospective cohort of patients with high-grade glioma treated with carmustine wafers or temozolomide on an intention-to-treat basis.
    Acta neurochirurgica, 2012, Volume: 154, Issue:2

    Topics: Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms;

2012
A clinical trial of bevacizumab, temozolomide, and radiation for newly diagnosed glioblastoma.
    Journal of neurosurgery, 2012, Volume: 116, Issue:2

    Topics: Adult; Aged; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Antineoplastic Agents, Alky

2012
A clinical trial of bevacizumab, temozolomide, and radiation for newly diagnosed glioblastoma.
    Journal of neurosurgery, 2012, Volume: 116, Issue:2

    Topics: Adult; Aged; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Antineoplastic Agents, Alky

2012
A clinical trial of bevacizumab, temozolomide, and radiation for newly diagnosed glioblastoma.
    Journal of neurosurgery, 2012, Volume: 116, Issue:2

    Topics: Adult; Aged; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Antineoplastic Agents, Alky

2012
Phase II study of short-course radiotherapy plus concomitant and adjuvant temozolomide in elderly patients with glioblastoma.
    International journal of radiation oncology, biology, physics, 2012, May-01, Volume: 83, Issue:1

    Topics: Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Chem

2012
Phase II study of short-course radiotherapy plus concomitant and adjuvant temozolomide in elderly patients with glioblastoma.
    International journal of radiation oncology, biology, physics, 2012, May-01, Volume: 83, Issue:1

    Topics: Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Chem

2012
Phase II study of short-course radiotherapy plus concomitant and adjuvant temozolomide in elderly patients with glioblastoma.
    International journal of radiation oncology, biology, physics, 2012, May-01, Volume: 83, Issue:1

    Topics: Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Chem

2012
Outcome, quality of life and cognitive function of patients with brain metastases from non-small cell lung cancer treated with whole brain radiotherapy combined with gefitinib or temozolomide. A randomised phase II trial of the Swiss Group for Clinical Ca
    European journal of cancer (Oxford, England : 1990), 2012, Volume: 48, Issue:3

    Topics: Aged; Aged, 80 and over; Antineoplastic Agents; Brain Neoplasms; Brief Psychiatric Rating Scale; Car

2012
Outcome, quality of life and cognitive function of patients with brain metastases from non-small cell lung cancer treated with whole brain radiotherapy combined with gefitinib or temozolomide. A randomised phase II trial of the Swiss Group for Clinical Ca
    European journal of cancer (Oxford, England : 1990), 2012, Volume: 48, Issue:3

    Topics: Aged; Aged, 80 and over; Antineoplastic Agents; Brain Neoplasms; Brief Psychiatric Rating Scale; Car

2012
Outcome, quality of life and cognitive function of patients with brain metastases from non-small cell lung cancer treated with whole brain radiotherapy combined with gefitinib or temozolomide. A randomised phase II trial of the Swiss Group for Clinical Ca
    European journal of cancer (Oxford, England : 1990), 2012, Volume: 48, Issue:3

    Topics: Aged; Aged, 80 and over; Antineoplastic Agents; Brain Neoplasms; Brief Psychiatric Rating Scale; Car

2012
Outcome, quality of life and cognitive function of patients with brain metastases from non-small cell lung cancer treated with whole brain radiotherapy combined with gefitinib or temozolomide. A randomised phase II trial of the Swiss Group for Clinical Ca
    European journal of cancer (Oxford, England : 1990), 2012, Volume: 48, Issue:3

    Topics: Aged; Aged, 80 and over; Antineoplastic Agents; Brain Neoplasms; Brief Psychiatric Rating Scale; Car

2012
Outcome, quality of life and cognitive function of patients with brain metastases from non-small cell lung cancer treated with whole brain radiotherapy combined with gefitinib or temozolomide. A randomised phase II trial of the Swiss Group for Clinical Ca
    European journal of cancer (Oxford, England : 1990), 2012, Volume: 48, Issue:3

    Topics: Aged; Aged, 80 and over; Antineoplastic Agents; Brain Neoplasms; Brief Psychiatric Rating Scale; Car

2012
Outcome, quality of life and cognitive function of patients with brain metastases from non-small cell lung cancer treated with whole brain radiotherapy combined with gefitinib or temozolomide. A randomised phase II trial of the Swiss Group for Clinical Ca
    European journal of cancer (Oxford, England : 1990), 2012, Volume: 48, Issue:3

    Topics: Aged; Aged, 80 and over; Antineoplastic Agents; Brain Neoplasms; Brief Psychiatric Rating Scale; Car

2012
Outcome, quality of life and cognitive function of patients with brain metastases from non-small cell lung cancer treated with whole brain radiotherapy combined with gefitinib or temozolomide. A randomised phase II trial of the Swiss Group for Clinical Ca
    European journal of cancer (Oxford, England : 1990), 2012, Volume: 48, Issue:3

    Topics: Aged; Aged, 80 and over; Antineoplastic Agents; Brain Neoplasms; Brief Psychiatric Rating Scale; Car

2012
Outcome, quality of life and cognitive function of patients with brain metastases from non-small cell lung cancer treated with whole brain radiotherapy combined with gefitinib or temozolomide. A randomised phase II trial of the Swiss Group for Clinical Ca
    European journal of cancer (Oxford, England : 1990), 2012, Volume: 48, Issue:3

    Topics: Aged; Aged, 80 and over; Antineoplastic Agents; Brain Neoplasms; Brief Psychiatric Rating Scale; Car

2012
Outcome, quality of life and cognitive function of patients with brain metastases from non-small cell lung cancer treated with whole brain radiotherapy combined with gefitinib or temozolomide. A randomised phase II trial of the Swiss Group for Clinical Ca
    European journal of cancer (Oxford, England : 1990), 2012, Volume: 48, Issue:3

    Topics: Aged; Aged, 80 and over; Antineoplastic Agents; Brain Neoplasms; Brief Psychiatric Rating Scale; Car

2012
Outcome, quality of life and cognitive function of patients with brain metastases from non-small cell lung cancer treated with whole brain radiotherapy combined with gefitinib or temozolomide. A randomised phase II trial of the Swiss Group for Clinical Ca
    European journal of cancer (Oxford, England : 1990), 2012, Volume: 48, Issue:3

    Topics: Aged; Aged, 80 and over; Antineoplastic Agents; Brain Neoplasms; Brief Psychiatric Rating Scale; Car

2012
Outcome, quality of life and cognitive function of patients with brain metastases from non-small cell lung cancer treated with whole brain radiotherapy combined with gefitinib or temozolomide. A randomised phase II trial of the Swiss Group for Clinical Ca
    European journal of cancer (Oxford, England : 1990), 2012, Volume: 48, Issue:3

    Topics: Aged; Aged, 80 and over; Antineoplastic Agents; Brain Neoplasms; Brief Psychiatric Rating Scale; Car

2012
Outcome, quality of life and cognitive function of patients with brain metastases from non-small cell lung cancer treated with whole brain radiotherapy combined with gefitinib or temozolomide. A randomised phase II trial of the Swiss Group for Clinical Ca
    European journal of cancer (Oxford, England : 1990), 2012, Volume: 48, Issue:3

    Topics: Aged; Aged, 80 and over; Antineoplastic Agents; Brain Neoplasms; Brief Psychiatric Rating Scale; Car

2012
Going past the data for temozolomide.
    Cancer chemotherapy and pharmacology, 2012, Volume: 69, Issue:4

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant; Dacarbazine; Glioblastom

2012
Going past the data for temozolomide.
    Cancer chemotherapy and pharmacology, 2012, Volume: 69, Issue:4

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant; Dacarbazine; Glioblastom

2012
Going past the data for temozolomide.
    Cancer chemotherapy and pharmacology, 2012, Volume: 69, Issue:4

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant; Dacarbazine; Glioblastom

2012
A phase I study of temozolomide and everolimus (RAD001) in patients with newly diagnosed and progressive glioblastoma either receiving or not receiving enzyme-inducing anticonvulsants: an NCIC CTG study.
    Investigational new drugs, 2012, Volume: 30, Issue:6

    Topics: Adult; Aged; Anticonvulsants; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols;

2012
A phase I study of temozolomide and everolimus (RAD001) in patients with newly diagnosed and progressive glioblastoma either receiving or not receiving enzyme-inducing anticonvulsants: an NCIC CTG study.
    Investigational new drugs, 2012, Volume: 30, Issue:6

    Topics: Adult; Aged; Anticonvulsants; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols;

2012
A phase I study of temozolomide and everolimus (RAD001) in patients with newly diagnosed and progressive glioblastoma either receiving or not receiving enzyme-inducing anticonvulsants: an NCIC CTG study.
    Investigational new drugs, 2012, Volume: 30, Issue:6

    Topics: Adult; Aged; Anticonvulsants; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols;

2012
A clinical review of treatment outcomes in glioblastoma multiforme--the validation in a non-trial population of the results of a randomised Phase III clinical trial: has a more radical approach improved survival?
    The British journal of radiology, 2012, Volume: 85, Issue:1017

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy, Adjuvant; Dacarb

2012
A clinical review of treatment outcomes in glioblastoma multiforme--the validation in a non-trial population of the results of a randomised Phase III clinical trial: has a more radical approach improved survival?
    The British journal of radiology, 2012, Volume: 85, Issue:1017

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy, Adjuvant; Dacarb

2012
A clinical review of treatment outcomes in glioblastoma multiforme--the validation in a non-trial population of the results of a randomised Phase III clinical trial: has a more radical approach improved survival?
    The British journal of radiology, 2012, Volume: 85, Issue:1017

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy, Adjuvant; Dacarb

2012
Whole-brain irradiation with concomitant daily fixed-dose temozolomide for brain metastases treatment: a randomised phase II trial.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2012, Volume: 102, Issue:2

    Topics: Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chi-Square Distribution

2012
Whole-brain irradiation with concomitant daily fixed-dose temozolomide for brain metastases treatment: a randomised phase II trial.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2012, Volume: 102, Issue:2

    Topics: Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chi-Square Distribution

2012
Whole-brain irradiation with concomitant daily fixed-dose temozolomide for brain metastases treatment: a randomised phase II trial.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2012, Volume: 102, Issue:2

    Topics: Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chi-Square Distribution

2012
A phase I study of LY317615 (enzastaurin) and temozolomide in patients with gliomas (EORTC trial 26054).
    Neuro-oncology, 2012, Volume: 14, Issue:3

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Dacarbazine; Female; G

2012
A phase I study of LY317615 (enzastaurin) and temozolomide in patients with gliomas (EORTC trial 26054).
    Neuro-oncology, 2012, Volume: 14, Issue:3

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Dacarbazine; Female; G

2012
A phase I study of LY317615 (enzastaurin) and temozolomide in patients with gliomas (EORTC trial 26054).
    Neuro-oncology, 2012, Volume: 14, Issue:3

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Dacarbazine; Female; G

2012
Phase II study of Gleevec plus hydroxyurea in adults with progressive or recurrent low-grade glioma.
    Cancer, 2012, Oct-01, Volume: 118, Issue:19

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemother

2012
Phase II study of Gleevec plus hydroxyurea in adults with progressive or recurrent low-grade glioma.
    Cancer, 2012, Oct-01, Volume: 118, Issue:19

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemother

2012
Phase II study of Gleevec plus hydroxyurea in adults with progressive or recurrent low-grade glioma.
    Cancer, 2012, Oct-01, Volume: 118, Issue:19

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemother

2012
[Comparison of two regimens of postoperative concurrent chemoradiotherapy in adult patients with grade III-IV cerebral gliomas].
    Nan fang yi ke da xue xue bao = Journal of Southern Medical University, 2012, Volume: 32, Issue:2

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Chemoradiotherap

2012
[Comparison of two regimens of postoperative concurrent chemoradiotherapy in adult patients with grade III-IV cerebral gliomas].
    Nan fang yi ke da xue xue bao = Journal of Southern Medical University, 2012, Volume: 32, Issue:2

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Chemoradiotherap

2012
[Comparison of two regimens of postoperative concurrent chemoradiotherapy in adult patients with grade III-IV cerebral gliomas].
    Nan fang yi ke da xue xue bao = Journal of Southern Medical University, 2012, Volume: 32, Issue:2

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Chemoradiotherap

2012
Results of phase I study of a multi-modality treatment for newly diagnosed glioblastoma multiforme using local implantation of concurrent BCNU wafers and permanent I-125 seeds followed by fractionated radiation and temozolomide chemotherapy.
    Journal of neuro-oncology, 2012, Volume: 108, Issue:3

    Topics: Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carmustine; Chemoradiotherapy; Daca

2012
Results of phase I study of a multi-modality treatment for newly diagnosed glioblastoma multiforme using local implantation of concurrent BCNU wafers and permanent I-125 seeds followed by fractionated radiation and temozolomide chemotherapy.
    Journal of neuro-oncology, 2012, Volume: 108, Issue:3

    Topics: Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carmustine; Chemoradiotherapy; Daca

2012
Results of phase I study of a multi-modality treatment for newly diagnosed glioblastoma multiforme using local implantation of concurrent BCNU wafers and permanent I-125 seeds followed by fractionated radiation and temozolomide chemotherapy.
    Journal of neuro-oncology, 2012, Volume: 108, Issue:3

    Topics: Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carmustine; Chemoradiotherapy; Daca

2012
Phase II trial of hypofractionated IMRT with temozolomide for patients with newly diagnosed glioblastoma multiforme.
    International journal of radiation oncology, biology, physics, 2012, Nov-01, Volume: 84, Issue:3

    Topics: Adult; Aged; Anti-Inflammatory Agents; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradi

2012
Phase II trial of hypofractionated IMRT with temozolomide for patients with newly diagnosed glioblastoma multiforme.
    International journal of radiation oncology, biology, physics, 2012, Nov-01, Volume: 84, Issue:3

    Topics: Adult; Aged; Anti-Inflammatory Agents; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradi

2012
Phase II trial of hypofractionated IMRT with temozolomide for patients with newly diagnosed glioblastoma multiforme.
    International journal of radiation oncology, biology, physics, 2012, Nov-01, Volume: 84, Issue:3

    Topics: Adult; Aged; Anti-Inflammatory Agents; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradi

2012
Phase II trial of hypofractionated IMRT with temozolomide for patients with newly diagnosed glioblastoma multiforme.
    International journal of radiation oncology, biology, physics, 2012, Nov-01, Volume: 84, Issue:3

    Topics: Adult; Aged; Anti-Inflammatory Agents; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradi

2012
Phase II trial of hypofractionated IMRT with temozolomide for patients with newly diagnosed glioblastoma multiforme.
    International journal of radiation oncology, biology, physics, 2012, Nov-01, Volume: 84, Issue:3

    Topics: Adult; Aged; Anti-Inflammatory Agents; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradi

2012
Phase II trial of hypofractionated IMRT with temozolomide for patients with newly diagnosed glioblastoma multiforme.
    International journal of radiation oncology, biology, physics, 2012, Nov-01, Volume: 84, Issue:3

    Topics: Adult; Aged; Anti-Inflammatory Agents; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradi

2012
Phase II trial of hypofractionated IMRT with temozolomide for patients with newly diagnosed glioblastoma multiforme.
    International journal of radiation oncology, biology, physics, 2012, Nov-01, Volume: 84, Issue:3

    Topics: Adult; Aged; Anti-Inflammatory Agents; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradi

2012
Phase II trial of hypofractionated IMRT with temozolomide for patients with newly diagnosed glioblastoma multiforme.
    International journal of radiation oncology, biology, physics, 2012, Nov-01, Volume: 84, Issue:3

    Topics: Adult; Aged; Anti-Inflammatory Agents; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradi

2012
Phase II trial of hypofractionated IMRT with temozolomide for patients with newly diagnosed glioblastoma multiforme.
    International journal of radiation oncology, biology, physics, 2012, Nov-01, Volume: 84, Issue:3

    Topics: Adult; Aged; Anti-Inflammatory Agents; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradi

2012
Phase II trial of hypofractionated IMRT with temozolomide for patients with newly diagnosed glioblastoma multiforme.
    International journal of radiation oncology, biology, physics, 2012, Nov-01, Volume: 84, Issue:3

    Topics: Adult; Aged; Anti-Inflammatory Agents; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradi

2012
Phase II trial of hypofractionated IMRT with temozolomide for patients with newly diagnosed glioblastoma multiforme.
    International journal of radiation oncology, biology, physics, 2012, Nov-01, Volume: 84, Issue:3

    Topics: Adult; Aged; Anti-Inflammatory Agents; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradi

2012
Phase II trial of hypofractionated IMRT with temozolomide for patients with newly diagnosed glioblastoma multiforme.
    International journal of radiation oncology, biology, physics, 2012, Nov-01, Volume: 84, Issue:3

    Topics: Adult; Aged; Anti-Inflammatory Agents; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradi

2012
A safety run-in and randomized phase 2 study of cilengitide combined with chemoradiation for newly diagnosed glioblastoma (NABTT 0306).
    Cancer, 2012, Nov-15, Volume: 118, Issue:22

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherap

2012
A safety run-in and randomized phase 2 study of cilengitide combined with chemoradiation for newly diagnosed glioblastoma (NABTT 0306).
    Cancer, 2012, Nov-15, Volume: 118, Issue:22

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherap

2012
A safety run-in and randomized phase 2 study of cilengitide combined with chemoradiation for newly diagnosed glioblastoma (NABTT 0306).
    Cancer, 2012, Nov-15, Volume: 118, Issue:22

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherap

2012
Quality assurance in the EORTC 22033-26033/CE5 phase III randomized trial for low grade glioma: the digital individual case review.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2012, Volume: 103, Issue:3

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Electron

2012
Quality assurance in the EORTC 22033-26033/CE5 phase III randomized trial for low grade glioma: the digital individual case review.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2012, Volume: 103, Issue:3

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Electron

2012
Quality assurance in the EORTC 22033-26033/CE5 phase III randomized trial for low grade glioma: the digital individual case review.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2012, Volume: 103, Issue:3

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Electron

2012
Temozolomide chemotherapy alone versus radiotherapy alone for malignant astrocytoma in the elderly: the NOA-08 randomised, phase 3 trial.
    The Lancet. Oncology, 2012, Volume: 13, Issue:7

    Topics: Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neoplasms; Dacarbazin

2012
Temozolomide chemotherapy alone versus radiotherapy alone for malignant astrocytoma in the elderly: the NOA-08 randomised, phase 3 trial.
    The Lancet. Oncology, 2012, Volume: 13, Issue:7

    Topics: Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neoplasms; Dacarbazin

2012
Temozolomide chemotherapy alone versus radiotherapy alone for malignant astrocytoma in the elderly: the NOA-08 randomised, phase 3 trial.
    The Lancet. Oncology, 2012, Volume: 13, Issue:7

    Topics: Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neoplasms; Dacarbazin

2012
Temozolomide chemotherapy alone versus radiotherapy alone for malignant astrocytoma in the elderly: the NOA-08 randomised, phase 3 trial.
    The Lancet. Oncology, 2012, Volume: 13, Issue:7

    Topics: Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neoplasms; Dacarbazin

2012
Temozolomide chemotherapy alone versus radiotherapy alone for malignant astrocytoma in the elderly: the NOA-08 randomised, phase 3 trial.
    The Lancet. Oncology, 2012, Volume: 13, Issue:7

    Topics: Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neoplasms; Dacarbazin

2012
Temozolomide chemotherapy alone versus radiotherapy alone for malignant astrocytoma in the elderly: the NOA-08 randomised, phase 3 trial.
    The Lancet. Oncology, 2012, Volume: 13, Issue:7

    Topics: Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neoplasms; Dacarbazin

2012
Temozolomide chemotherapy alone versus radiotherapy alone for malignant astrocytoma in the elderly: the NOA-08 randomised, phase 3 trial.
    The Lancet. Oncology, 2012, Volume: 13, Issue:7

    Topics: Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neoplasms; Dacarbazin

2012
Temozolomide chemotherapy alone versus radiotherapy alone for malignant astrocytoma in the elderly: the NOA-08 randomised, phase 3 trial.
    The Lancet. Oncology, 2012, Volume: 13, Issue:7

    Topics: Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neoplasms; Dacarbazin

2012
Temozolomide chemotherapy alone versus radiotherapy alone for malignant astrocytoma in the elderly: the NOA-08 randomised, phase 3 trial.
    The Lancet. Oncology, 2012, Volume: 13, Issue:7

    Topics: Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neoplasms; Dacarbazin

2012
Temozolomide chemotherapy alone versus radiotherapy alone for malignant astrocytoma in the elderly: the NOA-08 randomised, phase 3 trial.
    The Lancet. Oncology, 2012, Volume: 13, Issue:7

    Topics: Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neoplasms; Dacarbazin

2012
Temozolomide chemotherapy alone versus radiotherapy alone for malignant astrocytoma in the elderly: the NOA-08 randomised, phase 3 trial.
    The Lancet. Oncology, 2012, Volume: 13, Issue:7

    Topics: Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neoplasms; Dacarbazin

2012
Temozolomide chemotherapy alone versus radiotherapy alone for malignant astrocytoma in the elderly: the NOA-08 randomised, phase 3 trial.
    The Lancet. Oncology, 2012, Volume: 13, Issue:7

    Topics: Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neoplasms; Dacarbazin

2012
Impact of age and co-morbidities in patients with newly diagnosed glioblastoma: a pooled data analysis of three prospective mono-institutional phase II studies.
    Medical oncology (Northwood, London, England), 2012, Volume: 29, Issue:5

    Topics: Adult; Age Factors; Aged; Aged, 80 and over; Antineoplastic Agents; Brain Neoplasms; Combined Modali

2012
Impact of age and co-morbidities in patients with newly diagnosed glioblastoma: a pooled data analysis of three prospective mono-institutional phase II studies.
    Medical oncology (Northwood, London, England), 2012, Volume: 29, Issue:5

    Topics: Adult; Age Factors; Aged; Aged, 80 and over; Antineoplastic Agents; Brain Neoplasms; Combined Modali

2012
Impact of age and co-morbidities in patients with newly diagnosed glioblastoma: a pooled data analysis of three prospective mono-institutional phase II studies.
    Medical oncology (Northwood, London, England), 2012, Volume: 29, Issue:5

    Topics: Adult; Age Factors; Aged; Aged, 80 and over; Antineoplastic Agents; Brain Neoplasms; Combined Modali

2012
A phase I study of the combination of sorafenib with temozolomide and radiation therapy for the treatment of primary and recurrent high-grade gliomas.
    International journal of radiation oncology, biology, physics, 2013, Feb-01, Volume: 85, Issue:2

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Cell Line, Tumor; Cell

2013
A phase I study of the combination of sorafenib with temozolomide and radiation therapy for the treatment of primary and recurrent high-grade gliomas.
    International journal of radiation oncology, biology, physics, 2013, Feb-01, Volume: 85, Issue:2

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Cell Line, Tumor; Cell

2013
A phase I study of the combination of sorafenib with temozolomide and radiation therapy for the treatment of primary and recurrent high-grade gliomas.
    International journal of radiation oncology, biology, physics, 2013, Feb-01, Volume: 85, Issue:2

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Cell Line, Tumor; Cell

2013
Phase II study of concurrent radiation therapy, temozolomide, and bevacizumab followed by bevacizumab/everolimus as first-line treatment for patients with glioblastoma.
    Clinical advances in hematology & oncology : H&O, 2012, Volume: 10, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Antineop

2012
Phase II study of concurrent radiation therapy, temozolomide, and bevacizumab followed by bevacizumab/everolimus as first-line treatment for patients with glioblastoma.
    Clinical advances in hematology & oncology : H&O, 2012, Volume: 10, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Antineop

2012
Phase II study of concurrent radiation therapy, temozolomide, and bevacizumab followed by bevacizumab/everolimus as first-line treatment for patients with glioblastoma.
    Clinical advances in hematology & oncology : H&O, 2012, Volume: 10, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Antineop

2012
Phase I study of arsenic trioxide and temozolomide in combination with radiation therapy in patients with malignant gliomas.
    Journal of neuro-oncology, 2012, Volume: 110, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Arsenic Trioxide; Ar

2012
Phase I study of arsenic trioxide and temozolomide in combination with radiation therapy in patients with malignant gliomas.
    Journal of neuro-oncology, 2012, Volume: 110, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Arsenic Trioxide; Ar

2012
Phase I study of arsenic trioxide and temozolomide in combination with radiation therapy in patients with malignant gliomas.
    Journal of neuro-oncology, 2012, Volume: 110, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Arsenic Trioxide; Ar

2012
Temozolomide versus standard 6-week radiotherapy versus hypofractionated radiotherapy in patients older than 60 years with glioblastoma: the Nordic randomised, phase 3 trial.
    The Lancet. Oncology, 2012, Volume: 13, Issue:9

    Topics: Aged; Aged, 80 and over; Brain Neoplasms; Chemoradiotherapy, Adjuvant; Dacarbazine; Disease-Free Sur

2012
Temozolomide versus standard 6-week radiotherapy versus hypofractionated radiotherapy in patients older than 60 years with glioblastoma: the Nordic randomised, phase 3 trial.
    The Lancet. Oncology, 2012, Volume: 13, Issue:9

    Topics: Aged; Aged, 80 and over; Brain Neoplasms; Chemoradiotherapy, Adjuvant; Dacarbazine; Disease-Free Sur

2012
Temozolomide versus standard 6-week radiotherapy versus hypofractionated radiotherapy in patients older than 60 years with glioblastoma: the Nordic randomised, phase 3 trial.
    The Lancet. Oncology, 2012, Volume: 13, Issue:9

    Topics: Aged; Aged, 80 and over; Brain Neoplasms; Chemoradiotherapy, Adjuvant; Dacarbazine; Disease-Free Sur

2012
Diffusion-weighted MR imaging for the differentiation of true progression from pseudoprogression following concomitant radiotherapy with temozolomide in patients with newly diagnosed high-grade gliomas.
    Academic radiology, 2012, Volume: 19, Issue:11

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Artifacts; Brain Neoplasms; Chemoradioth

2012
Diffusion-weighted MR imaging for the differentiation of true progression from pseudoprogression following concomitant radiotherapy with temozolomide in patients with newly diagnosed high-grade gliomas.
    Academic radiology, 2012, Volume: 19, Issue:11

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Artifacts; Brain Neoplasms; Chemoradioth

2012
Diffusion-weighted MR imaging for the differentiation of true progression from pseudoprogression following concomitant radiotherapy with temozolomide in patients with newly diagnosed high-grade gliomas.
    Academic radiology, 2012, Volume: 19, Issue:11

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Artifacts; Brain Neoplasms; Chemoradioth

2012
Accelerated intensity-modulated radiotherapy plus temozolomide in patients with glioblastoma: a phase I dose-escalation study (ISIDE-BT-1).
    International journal of clinical oncology, 2013, Volume: 18, Issue:5

    Topics: Adult; Aged; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Dose Fractionation, Radiation;

2013
Accelerated intensity-modulated radiotherapy plus temozolomide in patients with glioblastoma: a phase I dose-escalation study (ISIDE-BT-1).
    International journal of clinical oncology, 2013, Volume: 18, Issue:5

    Topics: Adult; Aged; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Dose Fractionation, Radiation;

2013
Accelerated intensity-modulated radiotherapy plus temozolomide in patients with glioblastoma: a phase I dose-escalation study (ISIDE-BT-1).
    International journal of clinical oncology, 2013, Volume: 18, Issue:5

    Topics: Adult; Aged; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Dose Fractionation, Radiation;

2013
Chemosensitized radiosurgery for recurrent brain metastases.
    Journal of neuro-oncology, 2012, Volume: 110, Issue:2

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Female; Humans; Male;

2012
Chemosensitized radiosurgery for recurrent brain metastases.
    Journal of neuro-oncology, 2012, Volume: 110, Issue:2

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Female; Humans; Male;

2012
Chemosensitized radiosurgery for recurrent brain metastases.
    Journal of neuro-oncology, 2012, Volume: 110, Issue:2

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Female; Humans; Male;

2012
Phase I study of vorinostat in combination with temozolomide in patients with high-grade gliomas: North American Brain Tumor Consortium Study 04-03.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2012, Nov-01, Volume: 18, Issue:21

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Dac

2012
Phase I study of vorinostat in combination with temozolomide in patients with high-grade gliomas: North American Brain Tumor Consortium Study 04-03.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2012, Nov-01, Volume: 18, Issue:21

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Dac

2012
Phase I study of vorinostat in combination with temozolomide in patients with high-grade gliomas: North American Brain Tumor Consortium Study 04-03.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2012, Nov-01, Volume: 18, Issue:21

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Dac

2012
The addition of temozolomide does not change the pattern of progression of glioblastoma multiforme post-radiotherapy.
    Journal of medical imaging and radiation oncology, 2012, Volume: 56, Issue:5

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant; Dacarbazine

2012
The addition of temozolomide does not change the pattern of progression of glioblastoma multiforme post-radiotherapy.
    Journal of medical imaging and radiation oncology, 2012, Volume: 56, Issue:5

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant; Dacarbazine

2012
The addition of temozolomide does not change the pattern of progression of glioblastoma multiforme post-radiotherapy.
    Journal of medical imaging and radiation oncology, 2012, Volume: 56, Issue:5

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant; Dacarbazine

2012
Human umbilical vein endothelial cell vaccine therapy in patients with recurrent glioblastoma.
    Cancer science, 2013, Volume: 104, Issue:2

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cancer Vaccines; Chemotherapy, Adjuvant; Dacarba

2013
Human umbilical vein endothelial cell vaccine therapy in patients with recurrent glioblastoma.
    Cancer science, 2013, Volume: 104, Issue:2

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cancer Vaccines; Chemotherapy, Adjuvant; Dacarba

2013
Human umbilical vein endothelial cell vaccine therapy in patients with recurrent glioblastoma.
    Cancer science, 2013, Volume: 104, Issue:2

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cancer Vaccines; Chemotherapy, Adjuvant; Dacarba

2013
Limited margins using modern radiotherapy techniques does not increase marginal failure rate of glioblastoma.
    American journal of clinical oncology, 2014, Volume: 37, Issue:2

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Daca

2014
Limited margins using modern radiotherapy techniques does not increase marginal failure rate of glioblastoma.
    American journal of clinical oncology, 2014, Volume: 37, Issue:2

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Daca

2014
Limited margins using modern radiotherapy techniques does not increase marginal failure rate of glioblastoma.
    American journal of clinical oncology, 2014, Volume: 37, Issue:2

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Daca

2014
Phase II trial of continuous low-dose temozolomide for patients with recurrent malignant glioma.
    Neuro-oncology, 2013, Volume: 15, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Dos

2013
Phase II trial of continuous low-dose temozolomide for patients with recurrent malignant glioma.
    Neuro-oncology, 2013, Volume: 15, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Dos

2013
Phase II trial of continuous low-dose temozolomide for patients with recurrent malignant glioma.
    Neuro-oncology, 2013, Volume: 15, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Dos

2013
A phase I study of temozolomide and lapatinib combination in patients with recurrent high-grade gliomas.
    Journal of neurology, 2013, Volume: 260, Issue:6

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Dacarbazine; Disease-F

2013
A phase I study of temozolomide and lapatinib combination in patients with recurrent high-grade gliomas.
    Journal of neurology, 2013, Volume: 260, Issue:6

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Dacarbazine; Disease-F

2013
A phase I study of temozolomide and lapatinib combination in patients with recurrent high-grade gliomas.
    Journal of neurology, 2013, Volume: 260, Issue:6

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Dacarbazine; Disease-F

2013
"One week on-one week off": efficacy and side effects of dose-intensified temozolomide chemotherapy: experiences of a single center.
    Journal of neuro-oncology, 2013, Volume: 112, Issue:2

    Topics: Adult; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Disease Progression; Drug Ad

2013
"One week on-one week off": efficacy and side effects of dose-intensified temozolomide chemotherapy: experiences of a single center.
    Journal of neuro-oncology, 2013, Volume: 112, Issue:2

    Topics: Adult; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Disease Progression; Drug Ad

2013
"One week on-one week off": efficacy and side effects of dose-intensified temozolomide chemotherapy: experiences of a single center.
    Journal of neuro-oncology, 2013, Volume: 112, Issue:2

    Topics: Adult; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Disease Progression; Drug Ad

2013
Prospective study of carmustine wafers in combination with 6-month metronomic temozolomide and radiation therapy in newly diagnosed glioblastoma: preliminary results.
    Journal of neurosurgery, 2013, Volume: 118, Issue:4

    Topics: Administration, Metronomic; Administration, Oral; Adolescent; Adult; Aged; Antineoplastic Agents, Al

2013
Prospective study of carmustine wafers in combination with 6-month metronomic temozolomide and radiation therapy in newly diagnosed glioblastoma: preliminary results.
    Journal of neurosurgery, 2013, Volume: 118, Issue:4

    Topics: Administration, Metronomic; Administration, Oral; Adolescent; Adult; Aged; Antineoplastic Agents, Al

2013
Prospective study of carmustine wafers in combination with 6-month metronomic temozolomide and radiation therapy in newly diagnosed glioblastoma: preliminary results.
    Journal of neurosurgery, 2013, Volume: 118, Issue:4

    Topics: Administration, Metronomic; Administration, Oral; Adolescent; Adult; Aged; Antineoplastic Agents, Al

2013
Paclitaxel poliglumex, temozolomide, and radiation for newly diagnosed high-grade glioma: a Brown University Oncology Group Study.
    American journal of clinical oncology, 2014, Volume: 37, Issue:5

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brachytherapy; Brain Neoplasms; Chemora

2014
Paclitaxel poliglumex, temozolomide, and radiation for newly diagnosed high-grade glioma: a Brown University Oncology Group Study.
    American journal of clinical oncology, 2014, Volume: 37, Issue:5

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brachytherapy; Brain Neoplasms; Chemora

2014
Paclitaxel poliglumex, temozolomide, and radiation for newly diagnosed high-grade glioma: a Brown University Oncology Group Study.
    American journal of clinical oncology, 2014, Volume: 37, Issue:5

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brachytherapy; Brain Neoplasms; Chemora

2014
Can elderly patients with newly diagnosed glioblastoma be enrolled in radiochemotherapy trials?
    American journal of clinical oncology, 2015, Volume: 38, Issue:1

    Topics: Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Chem

2015
Can elderly patients with newly diagnosed glioblastoma be enrolled in radiochemotherapy trials?
    American journal of clinical oncology, 2015, Volume: 38, Issue:1

    Topics: Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Chem

2015
Can elderly patients with newly diagnosed glioblastoma be enrolled in radiochemotherapy trials?
    American journal of clinical oncology, 2015, Volume: 38, Issue:1

    Topics: Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Chem

2015
A phase 3 trial of whole brain radiation therapy and stereotactic radiosurgery alone versus WBRT and SRS with temozolomide or erlotinib for non-small cell lung cancer and 1 to 3 brain metastases: Radiation Therapy Oncology Group 0320.
    International journal of radiation oncology, biology, physics, 2013, Apr-01, Volume: 85, Issue:5

    Topics: Aged; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Brain Neoplasms; Carcinoma, Non-Smal

2013
A phase 3 trial of whole brain radiation therapy and stereotactic radiosurgery alone versus WBRT and SRS with temozolomide or erlotinib for non-small cell lung cancer and 1 to 3 brain metastases: Radiation Therapy Oncology Group 0320.
    International journal of radiation oncology, biology, physics, 2013, Apr-01, Volume: 85, Issue:5

    Topics: Aged; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Brain Neoplasms; Carcinoma, Non-Smal

2013
A phase 3 trial of whole brain radiation therapy and stereotactic radiosurgery alone versus WBRT and SRS with temozolomide or erlotinib for non-small cell lung cancer and 1 to 3 brain metastases: Radiation Therapy Oncology Group 0320.
    International journal of radiation oncology, biology, physics, 2013, Apr-01, Volume: 85, Issue:5

    Topics: Aged; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Brain Neoplasms; Carcinoma, Non-Smal

2013
Phase II randomized trial of temozolomide and concurrent radiotherapy in patients with brain metastases.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2002, Sep-01, Volume: 20, Issue:17

    Topics: Analysis of Variance; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy;

2002
Phase II randomized trial of temozolomide and concurrent radiotherapy in patients with brain metastases.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2002, Sep-01, Volume: 20, Issue:17

    Topics: Analysis of Variance; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy;

2002
Phase II randomized trial of temozolomide and concurrent radiotherapy in patients with brain metastases.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2002, Sep-01, Volume: 20, Issue:17

    Topics: Analysis of Variance; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy;

2002
A phase II pilot trial of concurrent biochemotherapy with cisplatin, vinblastine, temozolomide, interleukin 2, and IFN-alpha 2B in patients with metastatic melanoma.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2002, Volume: 8, Issue:10

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Cisplatin; Dacarbazine

2002
A phase II pilot trial of concurrent biochemotherapy with cisplatin, vinblastine, temozolomide, interleukin 2, and IFN-alpha 2B in patients with metastatic melanoma.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2002, Volume: 8, Issue:10

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Cisplatin; Dacarbazine

2002
A phase II pilot trial of concurrent biochemotherapy with cisplatin, vinblastine, temozolomide, interleukin 2, and IFN-alpha 2B in patients with metastatic melanoma.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2002, Volume: 8, Issue:10

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Cisplatin; Dacarbazine

2002
Temozolomide in second-line treatment after prior nitrosurea-based chemotherapy in glioblastoma multiforme: experience from a Portuguese institution.
    International journal of clinical pharmacology research, 2002, Volume: 22, Issue:1

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Drug Administration Sc

2002
Temozolomide in second-line treatment after prior nitrosurea-based chemotherapy in glioblastoma multiforme: experience from a Portuguese institution.
    International journal of clinical pharmacology research, 2002, Volume: 22, Issue:1

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Drug Administration Sc

2002
Temozolomide in second-line treatment after prior nitrosurea-based chemotherapy in glioblastoma multiforme: experience from a Portuguese institution.
    International journal of clinical pharmacology research, 2002, Volume: 22, Issue:1

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Drug Administration Sc

2002
Temozolomide in malignant gliomas of childhood: a United Kingdom Children's Cancer Study Group and French Society for Pediatric Oncology Intergroup Study.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2002, Dec-15, Volume: 20, Issue:24

    Topics: Adolescent; Antineoplastic Agents, Alkylating; Bone Marrow; Brain Neoplasms; Child; Child, Preschool

2002
Temozolomide in malignant gliomas of childhood: a United Kingdom Children's Cancer Study Group and French Society for Pediatric Oncology Intergroup Study.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2002, Dec-15, Volume: 20, Issue:24

    Topics: Adolescent; Antineoplastic Agents, Alkylating; Bone Marrow; Brain Neoplasms; Child; Child, Preschool

2002
Temozolomide in malignant gliomas of childhood: a United Kingdom Children's Cancer Study Group and French Society for Pediatric Oncology Intergroup Study.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2002, Dec-15, Volume: 20, Issue:24

    Topics: Adolescent; Antineoplastic Agents, Alkylating; Bone Marrow; Brain Neoplasms; Child; Child, Preschool

2002
Second-line chemotherapy with temozolomide in recurrent oligodendroglioma after PCV (procarbazine, lomustine and vincristine) chemotherapy: EORTC Brain Tumor Group phase II study 26972.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2003, Volume: 14, Issue:4

    Topics: Adult; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Brain Neop

2003
Second-line chemotherapy with temozolomide in recurrent oligodendroglioma after PCV (procarbazine, lomustine and vincristine) chemotherapy: EORTC Brain Tumor Group phase II study 26972.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2003, Volume: 14, Issue:4

    Topics: Adult; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Brain Neop

2003
Second-line chemotherapy with temozolomide in recurrent oligodendroglioma after PCV (procarbazine, lomustine and vincristine) chemotherapy: EORTC Brain Tumor Group phase II study 26972.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2003, Volume: 14, Issue:4

    Topics: Adult; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Brain Neop

2003
Phase I study of temozolomide and escalating doses of oral etoposide for adults with recurrent malignant glioma.
    Cancer, 2003, Apr-15, Volume: 97, Issue:8

    Topics: Administration, Oral; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms;

2003
Phase I study of temozolomide and escalating doses of oral etoposide for adults with recurrent malignant glioma.
    Cancer, 2003, Apr-15, Volume: 97, Issue:8

    Topics: Administration, Oral; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms;

2003
Phase I study of temozolomide and escalating doses of oral etoposide for adults with recurrent malignant glioma.
    Cancer, 2003, Apr-15, Volume: 97, Issue:8

    Topics: Administration, Oral; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms;

2003
Temozolomide in patients with advanced non-small cell lung cancer with and without brain metastases. a phase II study of the EORTC Lung Cancer Group (08965).
    European journal of cancer (Oxford, England : 1990), 2003, Volume: 39, Issue:9

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Carcinoma, Non-Small-Cell Lung; Dac

2003
Temozolomide in patients with advanced non-small cell lung cancer with and without brain metastases. a phase II study of the EORTC Lung Cancer Group (08965).
    European journal of cancer (Oxford, England : 1990), 2003, Volume: 39, Issue:9

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Carcinoma, Non-Small-Cell Lung; Dac

2003
Temozolomide in patients with advanced non-small cell lung cancer with and without brain metastases. a phase II study of the EORTC Lung Cancer Group (08965).
    European journal of cancer (Oxford, England : 1990), 2003, Volume: 39, Issue:9

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Carcinoma, Non-Small-Cell Lung; Dac

2003
Phase II study of first-line chemotherapy with temozolomide in recurrent oligodendroglial tumors: the European Organization for Research and Treatment of Cancer Brain Tumor Group Study 26971.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2003, Jul-01, Volume: 21, Issue:13

    Topics: Adult; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Disease Progression; Drug Ad

2003
Phase II study of first-line chemotherapy with temozolomide in recurrent oligodendroglial tumors: the European Organization for Research and Treatment of Cancer Brain Tumor Group Study 26971.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2003, Jul-01, Volume: 21, Issue:13

    Topics: Adult; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Disease Progression; Drug Ad

2003
Phase II study of first-line chemotherapy with temozolomide in recurrent oligodendroglial tumors: the European Organization for Research and Treatment of Cancer Brain Tumor Group Study 26971.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2003, Jul-01, Volume: 21, Issue:13

    Topics: Adult; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Disease Progression; Drug Ad

2003
Phase II study of first-line chemotherapy with temozolomide in recurrent oligodendroglial tumors: the European Organization for Research and Treatment of Cancer Brain Tumor Group Study 26971.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2003, Jul-01, Volume: 21, Issue:13

    Topics: Adult; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Disease Progression; Drug Ad

2003
Phase II study of first-line chemotherapy with temozolomide in recurrent oligodendroglial tumors: the European Organization for Research and Treatment of Cancer Brain Tumor Group Study 26971.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2003, Jul-01, Volume: 21, Issue:13

    Topics: Adult; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Disease Progression; Drug Ad

2003
Phase II study of first-line chemotherapy with temozolomide in recurrent oligodendroglial tumors: the European Organization for Research and Treatment of Cancer Brain Tumor Group Study 26971.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2003, Jul-01, Volume: 21, Issue:13

    Topics: Adult; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Disease Progression; Drug Ad

2003
Phase II study of first-line chemotherapy with temozolomide in recurrent oligodendroglial tumors: the European Organization for Research and Treatment of Cancer Brain Tumor Group Study 26971.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2003, Jul-01, Volume: 21, Issue:13

    Topics: Adult; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Disease Progression; Drug Ad

2003
Phase II study of first-line chemotherapy with temozolomide in recurrent oligodendroglial tumors: the European Organization for Research and Treatment of Cancer Brain Tumor Group Study 26971.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2003, Jul-01, Volume: 21, Issue:13

    Topics: Adult; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Disease Progression; Drug Ad

2003
Phase II study of first-line chemotherapy with temozolomide in recurrent oligodendroglial tumors: the European Organization for Research and Treatment of Cancer Brain Tumor Group Study 26971.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2003, Jul-01, Volume: 21, Issue:13

    Topics: Adult; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Disease Progression; Drug Ad

2003
Phase II study of first-line chemotherapy with temozolomide in recurrent oligodendroglial tumors: the European Organization for Research and Treatment of Cancer Brain Tumor Group Study 26971.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2003, Jul-01, Volume: 21, Issue:13

    Topics: Adult; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Disease Progression; Drug Ad

2003
Phase II study of first-line chemotherapy with temozolomide in recurrent oligodendroglial tumors: the European Organization for Research and Treatment of Cancer Brain Tumor Group Study 26971.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2003, Jul-01, Volume: 21, Issue:13

    Topics: Adult; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Disease Progression; Drug Ad

2003
Phase II study of first-line chemotherapy with temozolomide in recurrent oligodendroglial tumors: the European Organization for Research and Treatment of Cancer Brain Tumor Group Study 26971.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2003, Jul-01, Volume: 21, Issue:13

    Topics: Adult; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Disease Progression; Drug Ad

2003
Phase I study of temozolamide (TMZ) combined with procarbazine (PCB) in patients with gliomas.
    British journal of cancer, 2003, Jul-21, Volume: 89, Issue:2

    Topics: Administration, Oral; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Astro

2003
Phase I study of temozolamide (TMZ) combined with procarbazine (PCB) in patients with gliomas.
    British journal of cancer, 2003, Jul-21, Volume: 89, Issue:2

    Topics: Administration, Oral; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Astro

2003
Phase I study of temozolamide (TMZ) combined with procarbazine (PCB) in patients with gliomas.
    British journal of cancer, 2003, Jul-21, Volume: 89, Issue:2

    Topics: Administration, Oral; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Astro

2003
Phase II study of temozolomide plus thalidomide for the treatment of metastatic melanoma.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2003, Sep-01, Volume: 21, Issue:17

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Dac

2003
Phase II study of temozolomide plus thalidomide for the treatment of metastatic melanoma.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2003, Sep-01, Volume: 21, Issue:17

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Dac

2003
Phase II study of temozolomide plus thalidomide for the treatment of metastatic melanoma.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2003, Sep-01, Volume: 21, Issue:17

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Dac

2003
Phase II study of temozolomide plus thalidomide for the treatment of metastatic melanoma.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2003, Sep-01, Volume: 21, Issue:17

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Dac

2003
Phase II study of temozolomide plus thalidomide for the treatment of metastatic melanoma.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2003, Sep-01, Volume: 21, Issue:17

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Dac

2003
Phase II study of temozolomide plus thalidomide for the treatment of metastatic melanoma.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2003, Sep-01, Volume: 21, Issue:17

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Dac

2003
Phase II study of temozolomide plus thalidomide for the treatment of metastatic melanoma.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2003, Sep-01, Volume: 21, Issue:17

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Dac

2003
Phase II study of temozolomide plus thalidomide for the treatment of metastatic melanoma.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2003, Sep-01, Volume: 21, Issue:17

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Dac

2003
Phase II study of temozolomide plus thalidomide for the treatment of metastatic melanoma.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2003, Sep-01, Volume: 21, Issue:17

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Dac

2003
Phase II study of temozolomide plus thalidomide for the treatment of metastatic melanoma.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2003, Sep-01, Volume: 21, Issue:17

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Dac

2003
Phase II study of temozolomide plus thalidomide for the treatment of metastatic melanoma.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2003, Sep-01, Volume: 21, Issue:17

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Dac

2003
Phase II study of temozolomide plus thalidomide for the treatment of metastatic melanoma.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2003, Sep-01, Volume: 21, Issue:17

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Dac

2003
Population pharmacokinetics of temozolomide and metabolites in infants and children with primary central nervous system tumors.
    Cancer chemotherapy and pharmacology, 2003, Volume: 52, Issue:6

    Topics: Adolescent; Adult; Age Factors; Antineoplastic Agents, Alkylating; Area Under Curve; Biological Avai

2003
Population pharmacokinetics of temozolomide and metabolites in infants and children with primary central nervous system tumors.
    Cancer chemotherapy and pharmacology, 2003, Volume: 52, Issue:6

    Topics: Adolescent; Adult; Age Factors; Antineoplastic Agents, Alkylating; Area Under Curve; Biological Avai

2003
Population pharmacokinetics of temozolomide and metabolites in infants and children with primary central nervous system tumors.
    Cancer chemotherapy and pharmacology, 2003, Volume: 52, Issue:6

    Topics: Adolescent; Adult; Age Factors; Antineoplastic Agents, Alkylating; Area Under Curve; Biological Avai

2003
Pharmacokinetics of temozolomide given three times a day in pediatric and adult patients.
    Cancer chemotherapy and pharmacology, 2003, Volume: 52, Issue:6

    Topics: Administration, Oral; Adolescent; Adult; Antineoplastic Agents, Alkylating; Area Under Curve; Brain

2003
Pharmacokinetics of temozolomide given three times a day in pediatric and adult patients.
    Cancer chemotherapy and pharmacology, 2003, Volume: 52, Issue:6

    Topics: Administration, Oral; Adolescent; Adult; Antineoplastic Agents, Alkylating; Area Under Curve; Brain

2003
Pharmacokinetics of temozolomide given three times a day in pediatric and adult patients.
    Cancer chemotherapy and pharmacology, 2003, Volume: 52, Issue:6

    Topics: Administration, Oral; Adolescent; Adult; Antineoplastic Agents, Alkylating; Area Under Curve; Brain

2003
A first feasibility study of temozolomide for Japanese patients with recurrent anaplastic astrocytoma and glioblastoma multiforme.
    International journal of clinical oncology, 2003, Volume: 8, Issue:5

    Topics: Adult; Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neoplasms; Dacarbazine; Disease Progres

2003
A first feasibility study of temozolomide for Japanese patients with recurrent anaplastic astrocytoma and glioblastoma multiforme.
    International journal of clinical oncology, 2003, Volume: 8, Issue:5

    Topics: Adult; Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neoplasms; Dacarbazine; Disease Progres

2003
A first feasibility study of temozolomide for Japanese patients with recurrent anaplastic astrocytoma and glioblastoma multiforme.
    International journal of clinical oncology, 2003, Volume: 8, Issue:5

    Topics: Adult; Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neoplasms; Dacarbazine; Disease Progres

2003
Phase II study of primary temozolomide chemotherapy in patients with WHO grade II gliomas.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2003, Volume: 14, Issue:12

    Topics: Administration, Oral; Adult; Antineoplastic Agents; Brain Neoplasms; Dacarbazine; Disease Progressio

2003
Phase II study of primary temozolomide chemotherapy in patients with WHO grade II gliomas.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2003, Volume: 14, Issue:12

    Topics: Administration, Oral; Adult; Antineoplastic Agents; Brain Neoplasms; Dacarbazine; Disease Progressio

2003
Phase II study of primary temozolomide chemotherapy in patients with WHO grade II gliomas.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2003, Volume: 14, Issue:12

    Topics: Administration, Oral; Adult; Antineoplastic Agents; Brain Neoplasms; Dacarbazine; Disease Progressio

2003
Temozolomide chemotherapy for progressive low-grade glioma: clinical benefits and radiological response.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2003, Volume: 14, Issue:12

    Topics: Administration, Oral; Adult; Aged; Antineoplastic Agents; Brain Neoplasms; Dacarbazine; Disease Prog

2003
Temozolomide chemotherapy for progressive low-grade glioma: clinical benefits and radiological response.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2003, Volume: 14, Issue:12

    Topics: Administration, Oral; Adult; Aged; Antineoplastic Agents; Brain Neoplasms; Dacarbazine; Disease Prog

2003
Temozolomide chemotherapy for progressive low-grade glioma: clinical benefits and radiological response.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2003, Volume: 14, Issue:12

    Topics: Administration, Oral; Adult; Aged; Antineoplastic Agents; Brain Neoplasms; Dacarbazine; Disease Prog

2003
Dose-dense regimen of temozolomide given every other week in patients with primary central nervous system tumors.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2004, Volume: 15, Issue:1

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Dacarbazin

2004
Dose-dense regimen of temozolomide given every other week in patients with primary central nervous system tumors.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2004, Volume: 15, Issue:1

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Dacarbazin

2004
Dose-dense regimen of temozolomide given every other week in patients with primary central nervous system tumors.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2004, Volume: 15, Issue:1

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Dacarbazin

2004
Temozolomide in the treatment of recurrent malignant glioma.
    Cancer, 2004, Feb-01, Volume: 100, Issue:3

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Biopsy, Needle; Brain Neoplasms; Dacarba

2004
Temozolomide in the treatment of recurrent malignant glioma.
    Cancer, 2004, Feb-01, Volume: 100, Issue:3

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Biopsy, Needle; Brain Neoplasms; Dacarba

2004
Temozolomide in the treatment of recurrent malignant glioma.
    Cancer, 2004, Feb-01, Volume: 100, Issue:3

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Biopsy, Needle; Brain Neoplasms; Dacarba

2004
Phase 2 study of BCNU and temozolomide for recurrent glioblastoma multiforme: North American Brain Tumor Consortium study.
    Neuro-oncology, 2004, Volume: 6, Issue:1

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carmustine; Confidence

2004
Phase 2 study of BCNU and temozolomide for recurrent glioblastoma multiforme: North American Brain Tumor Consortium study.
    Neuro-oncology, 2004, Volume: 6, Issue:1

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carmustine; Confidence

2004
Phase 2 study of BCNU and temozolomide for recurrent glioblastoma multiforme: North American Brain Tumor Consortium study.
    Neuro-oncology, 2004, Volume: 6, Issue:1

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carmustine; Confidence

2004
Phase 2 study of BCNU and temozolomide for recurrent glioblastoma multiforme: North American Brain Tumor Consortium study.
    Neuro-oncology, 2004, Volume: 6, Issue:1

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carmustine; Confidence

2004
Phase 2 study of BCNU and temozolomide for recurrent glioblastoma multiforme: North American Brain Tumor Consortium study.
    Neuro-oncology, 2004, Volume: 6, Issue:1

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carmustine; Confidence

2004
Phase 2 study of BCNU and temozolomide for recurrent glioblastoma multiforme: North American Brain Tumor Consortium study.
    Neuro-oncology, 2004, Volume: 6, Issue:1

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carmustine; Confidence

2004
Phase 2 study of BCNU and temozolomide for recurrent glioblastoma multiforme: North American Brain Tumor Consortium study.
    Neuro-oncology, 2004, Volume: 6, Issue:1

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carmustine; Confidence

2004
Phase 2 study of BCNU and temozolomide for recurrent glioblastoma multiforme: North American Brain Tumor Consortium study.
    Neuro-oncology, 2004, Volume: 6, Issue:1

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carmustine; Confidence

2004
Phase 2 study of BCNU and temozolomide for recurrent glioblastoma multiforme: North American Brain Tumor Consortium study.
    Neuro-oncology, 2004, Volume: 6, Issue:1

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carmustine; Confidence

2004
Phase 2 study of BCNU and temozolomide for recurrent glioblastoma multiforme: North American Brain Tumor Consortium study.
    Neuro-oncology, 2004, Volume: 6, Issue:1

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carmustine; Confidence

2004
Phase 2 study of BCNU and temozolomide for recurrent glioblastoma multiforme: North American Brain Tumor Consortium study.
    Neuro-oncology, 2004, Volume: 6, Issue:1

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carmustine; Confidence

2004
Phase 2 study of BCNU and temozolomide for recurrent glioblastoma multiforme: North American Brain Tumor Consortium study.
    Neuro-oncology, 2004, Volume: 6, Issue:1

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carmustine; Confidence

2004
Phase 2 study of temozolomide and Caelyx in patients with recurrent glioblastoma multiforme.
    Neuro-oncology, 2004, Volume: 6, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Con

2004
Phase 2 study of temozolomide and Caelyx in patients with recurrent glioblastoma multiforme.
    Neuro-oncology, 2004, Volume: 6, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Con

2004
Phase 2 study of temozolomide and Caelyx in patients with recurrent glioblastoma multiforme.
    Neuro-oncology, 2004, Volume: 6, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Con

2004
Monitoring temozolomide treatment of low-grade glioma with proton magnetic resonance spectroscopy.
    British journal of cancer, 2004, Feb-23, Volume: 90, Issue:4

    Topics: Administration, Oral; Adult; Antineoplastic Agents, Alkylating; Brain Neoplasms; Choline; Dacarbazin

2004
Monitoring temozolomide treatment of low-grade glioma with proton magnetic resonance spectroscopy.
    British journal of cancer, 2004, Feb-23, Volume: 90, Issue:4

    Topics: Administration, Oral; Adult; Antineoplastic Agents, Alkylating; Brain Neoplasms; Choline; Dacarbazin

2004
Monitoring temozolomide treatment of low-grade glioma with proton magnetic resonance spectroscopy.
    British journal of cancer, 2004, Feb-23, Volume: 90, Issue:4

    Topics: Administration, Oral; Adult; Antineoplastic Agents, Alkylating; Brain Neoplasms; Choline; Dacarbazin

2004
Phase II trial of cisplatin plus temozolomide, in recurrent and progressive malignant glioma patients.
    Journal of neuro-oncology, 2004, Volume: 66, Issue:1-2

    Topics: Adult; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherap

2004
Phase II trial of cisplatin plus temozolomide, in recurrent and progressive malignant glioma patients.
    Journal of neuro-oncology, 2004, Volume: 66, Issue:1-2

    Topics: Adult; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherap

2004
Phase II trial of cisplatin plus temozolomide, in recurrent and progressive malignant glioma patients.
    Journal of neuro-oncology, 2004, Volume: 66, Issue:1-2

    Topics: Adult; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherap

2004
Salvage chemotherapy with cyclophosphamide for recurrent, temozolomide-refractory glioblastoma multiforme.
    Cancer, 2004, Mar-15, Volume: 100, Issue:6

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant; Cyclophosph

2004
Salvage chemotherapy with cyclophosphamide for recurrent, temozolomide-refractory glioblastoma multiforme.
    Cancer, 2004, Mar-15, Volume: 100, Issue:6

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant; Cyclophosph

2004
Salvage chemotherapy with cyclophosphamide for recurrent, temozolomide-refractory glioblastoma multiforme.
    Cancer, 2004, Mar-15, Volume: 100, Issue:6

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant; Cyclophosph

2004
Clinical trial substantiates the predictive value of O-6-methylguanine-DNA methyltransferase promoter methylation in glioblastoma patients treated with temozolomide.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2004, Mar-15, Volume: 10, Issue:6

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Biopsy; Brain Neoplasms; Combined Modality Therapy;

2004
Clinical trial substantiates the predictive value of O-6-methylguanine-DNA methyltransferase promoter methylation in glioblastoma patients treated with temozolomide.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2004, Mar-15, Volume: 10, Issue:6

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Biopsy; Brain Neoplasms; Combined Modality Therapy;

2004
Clinical trial substantiates the predictive value of O-6-methylguanine-DNA methyltransferase promoter methylation in glioblastoma patients treated with temozolomide.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2004, Mar-15, Volume: 10, Issue:6

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Biopsy; Brain Neoplasms; Combined Modality Therapy;

2004
Clinical trial substantiates the predictive value of O-6-methylguanine-DNA methyltransferase promoter methylation in glioblastoma patients treated with temozolomide.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2004, Mar-15, Volume: 10, Issue:6

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Biopsy; Brain Neoplasms; Combined Modality Therapy;

2004
Clinical trial substantiates the predictive value of O-6-methylguanine-DNA methyltransferase promoter methylation in glioblastoma patients treated with temozolomide.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2004, Mar-15, Volume: 10, Issue:6

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Biopsy; Brain Neoplasms; Combined Modality Therapy;

2004
Clinical trial substantiates the predictive value of O-6-methylguanine-DNA methyltransferase promoter methylation in glioblastoma patients treated with temozolomide.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2004, Mar-15, Volume: 10, Issue:6

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Biopsy; Brain Neoplasms; Combined Modality Therapy;

2004
Clinical trial substantiates the predictive value of O-6-methylguanine-DNA methyltransferase promoter methylation in glioblastoma patients treated with temozolomide.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2004, Mar-15, Volume: 10, Issue:6

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Biopsy; Brain Neoplasms; Combined Modality Therapy;

2004
Clinical trial substantiates the predictive value of O-6-methylguanine-DNA methyltransferase promoter methylation in glioblastoma patients treated with temozolomide.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2004, Mar-15, Volume: 10, Issue:6

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Biopsy; Brain Neoplasms; Combined Modality Therapy;

2004
Clinical trial substantiates the predictive value of O-6-methylguanine-DNA methyltransferase promoter methylation in glioblastoma patients treated with temozolomide.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2004, Mar-15, Volume: 10, Issue:6

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Biopsy; Brain Neoplasms; Combined Modality Therapy;

2004
Clinical trial substantiates the predictive value of O-6-methylguanine-DNA methyltransferase promoter methylation in glioblastoma patients treated with temozolomide.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2004, Mar-15, Volume: 10, Issue:6

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Biopsy; Brain Neoplasms; Combined Modality Therapy;

2004
Clinical trial substantiates the predictive value of O-6-methylguanine-DNA methyltransferase promoter methylation in glioblastoma patients treated with temozolomide.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2004, Mar-15, Volume: 10, Issue:6

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Biopsy; Brain Neoplasms; Combined Modality Therapy;

2004
Clinical trial substantiates the predictive value of O-6-methylguanine-DNA methyltransferase promoter methylation in glioblastoma patients treated with temozolomide.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2004, Mar-15, Volume: 10, Issue:6

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Biopsy; Brain Neoplasms; Combined Modality Therapy;

2004
Phase II study of neoadjuvant 1, 3-bis (2-chloroethyl)-1-nitrosourea and temozolomide for newly diagnosed anaplastic glioma: a North American Brain Tumor Consortium Trial.
    Cancer, 2004, Apr-15, Volume: 100, Issue:8

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Pro

2004
Phase II study of neoadjuvant 1, 3-bis (2-chloroethyl)-1-nitrosourea and temozolomide for newly diagnosed anaplastic glioma: a North American Brain Tumor Consortium Trial.
    Cancer, 2004, Apr-15, Volume: 100, Issue:8

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Pro

2004
Phase II study of neoadjuvant 1, 3-bis (2-chloroethyl)-1-nitrosourea and temozolomide for newly diagnosed anaplastic glioma: a North American Brain Tumor Consortium Trial.
    Cancer, 2004, Apr-15, Volume: 100, Issue:8

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Pro

2004
BCNU as second line therapy for recurrent high-grade glioma previously treated with Temozolomide.
    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2004, Volume: 11, Issue:4

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Carmustine; Dacarbazine; Disease Pr

2004
BCNU as second line therapy for recurrent high-grade glioma previously treated with Temozolomide.
    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2004, Volume: 11, Issue:4

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Carmustine; Dacarbazine; Disease Pr

2004
BCNU as second line therapy for recurrent high-grade glioma previously treated with Temozolomide.
    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2004, Volume: 11, Issue:4

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Carmustine; Dacarbazine; Disease Pr

2004
Temozolomide as prophylaxis for melanoma brain metastases.
    Melanoma research, 2004, Volume: 14, Issue:1

    Topics: Adult; Aged; Antibiotic Prophylaxis; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine

2004
Temozolomide as prophylaxis for melanoma brain metastases.
    Melanoma research, 2004, Volume: 14, Issue:1

    Topics: Adult; Aged; Antibiotic Prophylaxis; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine

2004
Temozolomide as prophylaxis for melanoma brain metastases.
    Melanoma research, 2004, Volume: 14, Issue:1

    Topics: Adult; Aged; Antibiotic Prophylaxis; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine

2004
First-line chemotherapy with cisplatin plus fractionated temozolomide in recurrent glioblastoma multiforme: a phase II study of the Gruppo Italiano Cooperativo di Neuro-Oncologia.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2004, May-01, Volume: 22, Issue:9

    Topics: Adult; Aged; Agranulocytosis; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Cispl

2004
First-line chemotherapy with cisplatin plus fractionated temozolomide in recurrent glioblastoma multiforme: a phase II study of the Gruppo Italiano Cooperativo di Neuro-Oncologia.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2004, May-01, Volume: 22, Issue:9

    Topics: Adult; Aged; Agranulocytosis; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Cispl

2004
First-line chemotherapy with cisplatin plus fractionated temozolomide in recurrent glioblastoma multiforme: a phase II study of the Gruppo Italiano Cooperativo di Neuro-Oncologia.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2004, May-01, Volume: 22, Issue:9

    Topics: Adult; Aged; Agranulocytosis; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Cispl

2004
Phase II study of temozolomide without radiotherapy in newly diagnosed glioblastoma multiforme in an elderly populations.
    Cancer, 2004, May-15, Volume: 100, Issue:10

    Topics: Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Female; Gl

2004
Phase II study of temozolomide without radiotherapy in newly diagnosed glioblastoma multiforme in an elderly populations.
    Cancer, 2004, May-15, Volume: 100, Issue:10

    Topics: Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Female; Gl

2004
Phase II study of temozolomide without radiotherapy in newly diagnosed glioblastoma multiforme in an elderly populations.
    Cancer, 2004, May-15, Volume: 100, Issue:10

    Topics: Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Female; Gl

2004
Temozolomide for the treatment of brain metastases associated with metastatic melanoma: a phase II study.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2004, Jun-01, Volume: 22, Issue:11

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Dis

2004
Temozolomide for the treatment of brain metastases associated with metastatic melanoma: a phase II study.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2004, Jun-01, Volume: 22, Issue:11

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Dis

2004
Temozolomide for the treatment of brain metastases associated with metastatic melanoma: a phase II study.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2004, Jun-01, Volume: 22, Issue:11

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Dis

2004
Phase I study pilot arms of radiotherapy and carmustine with temozolomide for anaplastic astrocytoma (Radiation Therapy Oncology Group 9813): implications for studies testing initial treatment of brain tumors.
    International journal of radiation oncology, biology, physics, 2004, Jul-15, Volume: 59, Issue:4

    Topics: Antineoplastic Combined Chemotherapy Protocols; Astrocytoma; Brain Neoplasms; Carmustine; Dacarbazin

2004
Phase I study pilot arms of radiotherapy and carmustine with temozolomide for anaplastic astrocytoma (Radiation Therapy Oncology Group 9813): implications for studies testing initial treatment of brain tumors.
    International journal of radiation oncology, biology, physics, 2004, Jul-15, Volume: 59, Issue:4

    Topics: Antineoplastic Combined Chemotherapy Protocols; Astrocytoma; Brain Neoplasms; Carmustine; Dacarbazin

2004
Phase I study pilot arms of radiotherapy and carmustine with temozolomide for anaplastic astrocytoma (Radiation Therapy Oncology Group 9813): implications for studies testing initial treatment of brain tumors.
    International journal of radiation oncology, biology, physics, 2004, Jul-15, Volume: 59, Issue:4

    Topics: Antineoplastic Combined Chemotherapy Protocols; Astrocytoma; Brain Neoplasms; Carmustine; Dacarbazin

2004
Temozolomide in paediatric high-grade glioma: a key for combination therapy?
    British journal of cancer, 2004, Aug-02, Volume: 91, Issue:3

    Topics: Administration, Oral; Adolescent; Adult; Antineoplastic Agents, Alkylating; Antineoplastic Combined

2004
Temozolomide in paediatric high-grade glioma: a key for combination therapy?
    British journal of cancer, 2004, Aug-02, Volume: 91, Issue:3

    Topics: Administration, Oral; Adolescent; Adult; Antineoplastic Agents, Alkylating; Antineoplastic Combined

2004
Temozolomide in paediatric high-grade glioma: a key for combination therapy?
    British journal of cancer, 2004, Aug-02, Volume: 91, Issue:3

    Topics: Administration, Oral; Adolescent; Adult; Antineoplastic Agents, Alkylating; Antineoplastic Combined

2004
Initial chemotherapy in gliomatosis cerebri.
    Neurology, 2004, Jul-27, Volume: 63, Issue:2

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Antineoplastic Combin

2004
Initial chemotherapy in gliomatosis cerebri.
    Neurology, 2004, Jul-27, Volume: 63, Issue:2

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Antineoplastic Combin

2004
Initial chemotherapy in gliomatosis cerebri.
    Neurology, 2004, Jul-27, Volume: 63, Issue:2

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Antineoplastic Combin

2004
Chemotherapy as initial treatment in gliomatosis cerebri: results with temozolomide.
    Neurology, 2004, Jul-27, Volume: 63, Issue:2

    Topics: Adolescent; Adult; Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neoplasms; Combined Modalit

2004
Chemotherapy as initial treatment in gliomatosis cerebri: results with temozolomide.
    Neurology, 2004, Jul-27, Volume: 63, Issue:2

    Topics: Adolescent; Adult; Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neoplasms; Combined Modalit

2004
Chemotherapy as initial treatment in gliomatosis cerebri: results with temozolomide.
    Neurology, 2004, Jul-27, Volume: 63, Issue:2

    Topics: Adolescent; Adult; Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neoplasms; Combined Modalit

2004
Phase 1 study of 28-day, low-dose temozolomide and BCNU in the treatment of malignant gliomas after radiation therapy.
    Neuro-oncology, 2004, Volume: 6, Issue:3

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Astrocytoma; Brain Neoplasms; Carmustin

2004
Phase 1 study of 28-day, low-dose temozolomide and BCNU in the treatment of malignant gliomas after radiation therapy.
    Neuro-oncology, 2004, Volume: 6, Issue:3

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Astrocytoma; Brain Neoplasms; Carmustin

2004
Phase 1 study of 28-day, low-dose temozolomide and BCNU in the treatment of malignant gliomas after radiation therapy.
    Neuro-oncology, 2004, Volume: 6, Issue:3

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Astrocytoma; Brain Neoplasms; Carmustin

2004
Phase 1 study of 28-day, low-dose temozolomide and BCNU in the treatment of malignant gliomas after radiation therapy.
    Neuro-oncology, 2004, Volume: 6, Issue:3

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Astrocytoma; Brain Neoplasms; Carmustin

2004
Phase 1 study of 28-day, low-dose temozolomide and BCNU in the treatment of malignant gliomas after radiation therapy.
    Neuro-oncology, 2004, Volume: 6, Issue:3

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Astrocytoma; Brain Neoplasms; Carmustin

2004
Phase 1 study of 28-day, low-dose temozolomide and BCNU in the treatment of malignant gliomas after radiation therapy.
    Neuro-oncology, 2004, Volume: 6, Issue:3

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Astrocytoma; Brain Neoplasms; Carmustin

2004
Phase 1 study of 28-day, low-dose temozolomide and BCNU in the treatment of malignant gliomas after radiation therapy.
    Neuro-oncology, 2004, Volume: 6, Issue:3

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Astrocytoma; Brain Neoplasms; Carmustin

2004
Phase 1 study of 28-day, low-dose temozolomide and BCNU in the treatment of malignant gliomas after radiation therapy.
    Neuro-oncology, 2004, Volume: 6, Issue:3

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Astrocytoma; Brain Neoplasms; Carmustin

2004
Phase 1 study of 28-day, low-dose temozolomide and BCNU in the treatment of malignant gliomas after radiation therapy.
    Neuro-oncology, 2004, Volume: 6, Issue:3

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Astrocytoma; Brain Neoplasms; Carmustin

2004
Phase 1 study of 28-day, low-dose temozolomide and BCNU in the treatment of malignant gliomas after radiation therapy.
    Neuro-oncology, 2004, Volume: 6, Issue:3

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Astrocytoma; Brain Neoplasms; Carmustin

2004
Phase 1 study of 28-day, low-dose temozolomide and BCNU in the treatment of malignant gliomas after radiation therapy.
    Neuro-oncology, 2004, Volume: 6, Issue:3

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Astrocytoma; Brain Neoplasms; Carmustin

2004
Phase 1 study of 28-day, low-dose temozolomide and BCNU in the treatment of malignant gliomas after radiation therapy.
    Neuro-oncology, 2004, Volume: 6, Issue:3

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Astrocytoma; Brain Neoplasms; Carmustin

2004
Immediate post-radiotherapy changes in malignant glioma can mimic tumor progression.
    Neurology, 2004, Aug-10, Volume: 63, Issue:3

    Topics: Antineoplastic Combined Chemotherapy Protocols; Artifacts; Astrocytoma; Brain Edema; Brain Neoplasms

2004
Immediate post-radiotherapy changes in malignant glioma can mimic tumor progression.
    Neurology, 2004, Aug-10, Volume: 63, Issue:3

    Topics: Antineoplastic Combined Chemotherapy Protocols; Artifacts; Astrocytoma; Brain Edema; Brain Neoplasms

2004
Immediate post-radiotherapy changes in malignant glioma can mimic tumor progression.
    Neurology, 2004, Aug-10, Volume: 63, Issue:3

    Topics: Antineoplastic Combined Chemotherapy Protocols; Artifacts; Astrocytoma; Brain Edema; Brain Neoplasms

2004
The effect of temozolomide-based chemotherapy in patients with cerebral metastases from melanoma.
    Melanoma research, 2004, Volume: 14, Issue:4

    Topics: Adult; Aged; Brain Neoplasms; Dacarbazine; Disease Progression; Drug Therapy, Combination; Female; H

2004
The effect of temozolomide-based chemotherapy in patients with cerebral metastases from melanoma.
    Melanoma research, 2004, Volume: 14, Issue:4

    Topics: Adult; Aged; Brain Neoplasms; Dacarbazine; Disease Progression; Drug Therapy, Combination; Female; H

2004
The effect of temozolomide-based chemotherapy in patients with cerebral metastases from melanoma.
    Melanoma research, 2004, Volume: 14, Issue:4

    Topics: Adult; Aged; Brain Neoplasms; Dacarbazine; Disease Progression; Drug Therapy, Combination; Female; H

2004
Salvage PCV chemotherapy for temozolomide-resistant oligodendrogliomas.
    Neurology, 2004, Sep-14, Volume: 63, Issue:5

    Topics: Adult; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Astrocytom

2004
Salvage PCV chemotherapy for temozolomide-resistant oligodendrogliomas.
    Neurology, 2004, Sep-14, Volume: 63, Issue:5

    Topics: Adult; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Astrocytom

2004
Salvage PCV chemotherapy for temozolomide-resistant oligodendrogliomas.
    Neurology, 2004, Sep-14, Volume: 63, Issue:5

    Topics: Adult; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Astrocytom

2004
Temozolomide treatment in glioma--experiences in two university hospitals in Finland.
    Acta oncologica (Stockholm, Sweden), 2004, Volume: 43, Issue:6

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cost-Benefit Analysis; Dacarbazine;

2004
Temozolomide treatment in glioma--experiences in two university hospitals in Finland.
    Acta oncologica (Stockholm, Sweden), 2004, Volume: 43, Issue:6

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cost-Benefit Analysis; Dacarbazine;

2004
Temozolomide treatment in glioma--experiences in two university hospitals in Finland.
    Acta oncologica (Stockholm, Sweden), 2004, Volume: 43, Issue:6

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cost-Benefit Analysis; Dacarbazine;

2004
Phase II study of temozolomide and thalidomide with radiation therapy for newly diagnosed glioblastoma multiforme.
    International journal of radiation oncology, biology, physics, 2004, Oct-01, Volume: 60, Issue:2

    Topics: Adult; Aged; Angiogenesis Inhibitors; Antineoplastic Agents, Alkylating; Antineoplastic Combined Che

2004
Phase II study of temozolomide and thalidomide with radiation therapy for newly diagnosed glioblastoma multiforme.
    International journal of radiation oncology, biology, physics, 2004, Oct-01, Volume: 60, Issue:2

    Topics: Adult; Aged; Angiogenesis Inhibitors; Antineoplastic Agents, Alkylating; Antineoplastic Combined Che

2004
Phase II study of temozolomide and thalidomide with radiation therapy for newly diagnosed glioblastoma multiforme.
    International journal of radiation oncology, biology, physics, 2004, Oct-01, Volume: 60, Issue:2

    Topics: Adult; Aged; Angiogenesis Inhibitors; Antineoplastic Agents, Alkylating; Antineoplastic Combined Che

2004
Combined treatment of glioblastoma patients with locoregional pre-targeted 90Y-biotin radioimmunotherapy and temozolomide.
    The quarterly journal of nuclear medicine and molecular imaging : official publication of the Italian Association of Nuclear Medicine (AIMN) [and] the International Association of Radiopharmacology (IAR), [and] Section of the Society of..., 2004, Volume: 48, Issue:3

    Topics: Antineoplastic Agents, Alkylating; Biotin; Brain Neoplasms; Chemotherapy, Adjuvant; Combined Modalit

2004
Combined treatment of glioblastoma patients with locoregional pre-targeted 90Y-biotin radioimmunotherapy and temozolomide.
    The quarterly journal of nuclear medicine and molecular imaging : official publication of the Italian Association of Nuclear Medicine (AIMN) [and] the International Association of Radiopharmacology (IAR), [and] Section of the Society of..., 2004, Volume: 48, Issue:3

    Topics: Antineoplastic Agents, Alkylating; Biotin; Brain Neoplasms; Chemotherapy, Adjuvant; Combined Modalit

2004
Combined treatment of glioblastoma patients with locoregional pre-targeted 90Y-biotin radioimmunotherapy and temozolomide.
    The quarterly journal of nuclear medicine and molecular imaging : official publication of the Italian Association of Nuclear Medicine (AIMN) [and] the International Association of Radiopharmacology (IAR), [and] Section of the Society of..., 2004, Volume: 48, Issue:3

    Topics: Antineoplastic Agents, Alkylating; Biotin; Brain Neoplasms; Chemotherapy, Adjuvant; Combined Modalit

2004
Phase II study of concurrent continuous Temozolomide (TMZ) and Tamoxifen (TMX) for recurrent malignant astrocytic gliomas.
    Journal of neuro-oncology, 2004, Volume: 70, Issue:1

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Astrocytoma; Brain Neoplasms; Dacarbazine; Fe

2004
Phase II study of concurrent continuous Temozolomide (TMZ) and Tamoxifen (TMX) for recurrent malignant astrocytic gliomas.
    Journal of neuro-oncology, 2004, Volume: 70, Issue:1

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Astrocytoma; Brain Neoplasms; Dacarbazine; Fe

2004
Phase II study of concurrent continuous Temozolomide (TMZ) and Tamoxifen (TMX) for recurrent malignant astrocytic gliomas.
    Journal of neuro-oncology, 2004, Volume: 70, Issue:1

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Astrocytoma; Brain Neoplasms; Dacarbazine; Fe

2004
Second-line chemotherapy with irinotecan plus carmustine in glioblastoma recurrent or progressive after first-line temozolomide chemotherapy: a phase II study of the Gruppo Italiano Cooperativo di Neuro-Oncologia (GICNO).
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2004, Dec-01, Volume: 22, Issue:23

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Camptothecin; Carmusti

2004
Second-line chemotherapy with irinotecan plus carmustine in glioblastoma recurrent or progressive after first-line temozolomide chemotherapy: a phase II study of the Gruppo Italiano Cooperativo di Neuro-Oncologia (GICNO).
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2004, Dec-01, Volume: 22, Issue:23

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Camptothecin; Carmusti

2004
Second-line chemotherapy with irinotecan plus carmustine in glioblastoma recurrent or progressive after first-line temozolomide chemotherapy: a phase II study of the Gruppo Italiano Cooperativo di Neuro-Oncologia (GICNO).
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2004, Dec-01, Volume: 22, Issue:23

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Camptothecin; Carmusti

2004
Temozolomide and concomitant whole brain radiotherapy in patients with brain metastases: a phase II randomized trial.
    International journal of radiation oncology, biology, physics, 2005, Jan-01, Volume: 61, Issue:1

    Topics: Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Cranial Irradia

2005
Temozolomide and concomitant whole brain radiotherapy in patients with brain metastases: a phase II randomized trial.
    International journal of radiation oncology, biology, physics, 2005, Jan-01, Volume: 61, Issue:1

    Topics: Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Cranial Irradia

2005
Temozolomide and concomitant whole brain radiotherapy in patients with brain metastases: a phase II randomized trial.
    International journal of radiation oncology, biology, physics, 2005, Jan-01, Volume: 61, Issue:1

    Topics: Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Cranial Irradia

2005
Temozolomide chemotherapy of patients with recurrent anaplastic astrocytomas and glioblastomas.
    Ideggyogyaszati szemle, 2004, Nov-20, Volume: 57, Issue:11-12

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neoplasms; Dacarbazine; Disease P

2004
Temozolomide chemotherapy of patients with recurrent anaplastic astrocytomas and glioblastomas.
    Ideggyogyaszati szemle, 2004, Nov-20, Volume: 57, Issue:11-12

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neoplasms; Dacarbazine; Disease P

2004
Temozolomide chemotherapy of patients with recurrent anaplastic astrocytomas and glioblastomas.
    Ideggyogyaszati szemle, 2004, Nov-20, Volume: 57, Issue:11-12

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neoplasms; Dacarbazine; Disease P

2004
Phase II study of temozolomide and cisplatin as primary treatment prior to radiotherapy in newly diagnosed glioblastoma multiforme patients with measurable disease. A study of the Spanish Medical Neuro-Oncology Group (GENOM).
    Journal of neuro-oncology, 2004, Volume: 70, Issue:3

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Cisplatin; Combined Mo

2004
Phase II study of temozolomide and cisplatin as primary treatment prior to radiotherapy in newly diagnosed glioblastoma multiforme patients with measurable disease. A study of the Spanish Medical Neuro-Oncology Group (GENOM).
    Journal of neuro-oncology, 2004, Volume: 70, Issue:3

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Cisplatin; Combined Mo

2004
Phase II study of temozolomide and cisplatin as primary treatment prior to radiotherapy in newly diagnosed glioblastoma multiforme patients with measurable disease. A study of the Spanish Medical Neuro-Oncology Group (GENOM).
    Journal of neuro-oncology, 2004, Volume: 70, Issue:3

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Cisplatin; Combined Mo

2004
Temozolomide (TMZ) combined with cisplatin (CDDP) in patients with brain metastases from solid tumors: a Hellenic Cooperative Oncology Group (HeCOG) Phase II study.
    Journal of neuro-oncology, 2005, Volume: 71, Issue:1

    Topics: Adult; Aged; Alopecia; Anemia; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Brea

2005
Temozolomide (TMZ) combined with cisplatin (CDDP) in patients with brain metastases from solid tumors: a Hellenic Cooperative Oncology Group (HeCOG) Phase II study.
    Journal of neuro-oncology, 2005, Volume: 71, Issue:1

    Topics: Adult; Aged; Alopecia; Anemia; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Brea

2005
Temozolomide (TMZ) combined with cisplatin (CDDP) in patients with brain metastases from solid tumors: a Hellenic Cooperative Oncology Group (HeCOG) Phase II study.
    Journal of neuro-oncology, 2005, Volume: 71, Issue:1

    Topics: Adult; Aged; Alopecia; Anemia; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Brea

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2005
Randomized phase II study of temozolomide and radiotherapy compared with radiotherapy alone in newly diagnosed glioblastoma multiforme.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2005, Apr-01, Volume: 23, Issue:10

    Topics: Adult; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; D

2005
Randomized phase II study of temozolomide and radiotherapy compared with radiotherapy alone in newly diagnosed glioblastoma multiforme.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2005, Apr-01, Volume: 23, Issue:10

    Topics: Adult; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; D

2005
Randomized phase II study of temozolomide and radiotherapy compared with radiotherapy alone in newly diagnosed glioblastoma multiforme.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2005, Apr-01, Volume: 23, Issue:10

    Topics: Adult; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; D

2005
Cost of temozolomide therapy and global care for recurrent malignant gliomas followed until death.
    Neuro-oncology, 2005, Volume: 7, Issue:2

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cost of Illness; Cost-Benefit Analy

2005
Cost of temozolomide therapy and global care for recurrent malignant gliomas followed until death.
    Neuro-oncology, 2005, Volume: 7, Issue:2

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cost of Illness; Cost-Benefit Analy

2005
Cost of temozolomide therapy and global care for recurrent malignant gliomas followed until death.
    Neuro-oncology, 2005, Volume: 7, Issue:2

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cost of Illness; Cost-Benefit Analy

2005
Temozolomide plus thalidomide in patients with brain metastases from melanoma: a phase II study.
    Cancer, 2005, Jun-15, Volume: 103, Issue:12

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Dac

2005
Temozolomide plus thalidomide in patients with brain metastases from melanoma: a phase II study.
    Cancer, 2005, Jun-15, Volume: 103, Issue:12

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Dac

2005
Temozolomide plus thalidomide in patients with brain metastases from melanoma: a phase II study.
    Cancer, 2005, Jun-15, Volume: 103, Issue:12

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Dac

2005
Concomitant chemoradiotherapy followed by adjuvant temozolomide improves survival in glioblastoma multiforme.
    Current neurology and neuroscience reports, 2005, Volume: 5, Issue:3

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant; Combined Modality Therap

2005
Concomitant chemoradiotherapy followed by adjuvant temozolomide improves survival in glioblastoma multiforme.
    Current neurology and neuroscience reports, 2005, Volume: 5, Issue:3

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant; Combined Modality Therap

2005
Concomitant chemoradiotherapy followed by adjuvant temozolomide improves survival in glioblastoma multiforme.
    Current neurology and neuroscience reports, 2005, Volume: 5, Issue:3

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant; Combined Modality Therap

2005
Temozolomide combined with irradiation as postoperative treatment of primary glioblastoma multiforme. Phase I/II study.
    Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 2005, Volume: 181, Issue:6

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Blood Cell Count; Brain Neoplasms; Combined Modality

2005
Temozolomide combined with irradiation as postoperative treatment of primary glioblastoma multiforme. Phase I/II study.
    Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 2005, Volume: 181, Issue:6

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Blood Cell Count; Brain Neoplasms; Combined Modality

2005
Temozolomide combined with irradiation as postoperative treatment of primary glioblastoma multiforme. Phase I/II study.
    Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 2005, Volume: 181, Issue:6

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Blood Cell Count; Brain Neoplasms; Combined Modality

2005
Phase II study of temozolomide plus pegylated liposomal doxorubicin in the treatment of brain metastases from solid tumours.
    Cancer chemotherapy and pharmacology, 2006, Volume: 57, Issue:1

    Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols

2006
Phase II study of temozolomide plus pegylated liposomal doxorubicin in the treatment of brain metastases from solid tumours.
    Cancer chemotherapy and pharmacology, 2006, Volume: 57, Issue:1

    Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols

2006
Phase II study of temozolomide plus pegylated liposomal doxorubicin in the treatment of brain metastases from solid tumours.
    Cancer chemotherapy and pharmacology, 2006, Volume: 57, Issue:1

    Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols

2006
Oral temozolomide in heavily pre-treated brain metastases from non-small cell lung cancer: phase II study.
    Lung cancer (Amsterdam, Netherlands), 2005, Volume: 50, Issue:2

    Topics: Administration, Oral; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Carcinoma, Non-Small

2005
Oral temozolomide in heavily pre-treated brain metastases from non-small cell lung cancer: phase II study.
    Lung cancer (Amsterdam, Netherlands), 2005, Volume: 50, Issue:2

    Topics: Administration, Oral; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Carcinoma, Non-Small

2005
Oral temozolomide in heavily pre-treated brain metastases from non-small cell lung cancer: phase II study.
    Lung cancer (Amsterdam, Netherlands), 2005, Volume: 50, Issue:2

    Topics: Administration, Oral; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Carcinoma, Non-Small

2005
Phase I trial of irinotecan plus temozolomide in adults with recurrent malignant glioma.
    Cancer, 2005, Oct-01, Volume: 104, Issue:7

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Camptothecin; Dacarbaz

2005
Phase I trial of irinotecan plus temozolomide in adults with recurrent malignant glioma.
    Cancer, 2005, Oct-01, Volume: 104, Issue:7

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Camptothecin; Dacarbaz

2005
Phase I trial of irinotecan plus temozolomide in adults with recurrent malignant glioma.
    Cancer, 2005, Oct-01, Volume: 104, Issue:7

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Camptothecin; Dacarbaz

2005
A phase II study of biochemotherapy for advanced melanoma incorporating temozolomide, decrescendo interleukin-2 and GM-CSF.
    Cancer investigation, 2005, Volume: 23, Issue:4

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Brai

2005
A phase II study of biochemotherapy for advanced melanoma incorporating temozolomide, decrescendo interleukin-2 and GM-CSF.
    Cancer investigation, 2005, Volume: 23, Issue:4

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Brai

2005
A phase II study of biochemotherapy for advanced melanoma incorporating temozolomide, decrescendo interleukin-2 and GM-CSF.
    Cancer investigation, 2005, Volume: 23, Issue:4

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Brai

2005
Temozolomide with or without radiotherapy in melanoma with unresectable brain metastases.
    Journal of neuro-oncology, 2006, Volume: 76, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2006
Temozolomide with or without radiotherapy in melanoma with unresectable brain metastases.
    Journal of neuro-oncology, 2006, Volume: 76, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2006
Temozolomide with or without radiotherapy in melanoma with unresectable brain metastases.
    Journal of neuro-oncology, 2006, Volume: 76, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2006
Phase I study of temozolomide and lomustine in the treatment of high grade malignant glioma.
    Frontiers in bioscience : a journal and virtual library, 2006, Jan-01, Volume: 11

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Brai

2006
Phase I study of temozolomide and lomustine in the treatment of high grade malignant glioma.
    Frontiers in bioscience : a journal and virtual library, 2006, Jan-01, Volume: 11

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Brai

2006
Phase I study of temozolomide and lomustine in the treatment of high grade malignant glioma.
    Frontiers in bioscience : a journal and virtual library, 2006, Jan-01, Volume: 11

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Brai

2006
Phase I trial of temozolomide plus O6-benzylguanine for patients with recurrent or progressive malignant glioma.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2005, Oct-01, Volume: 23, Issue:28

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Dacarbazine; Disease P

2005
Phase I trial of temozolomide plus O6-benzylguanine for patients with recurrent or progressive malignant glioma.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2005, Oct-01, Volume: 23, Issue:28

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Dacarbazine; Disease P

2005
Phase I trial of temozolomide plus O6-benzylguanine for patients with recurrent or progressive malignant glioma.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2005, Oct-01, Volume: 23, Issue:28

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Dacarbazine; Disease P

2005
Temozolomide after radiotherapy for newly diagnosed high-grade glioma and unfavorable low-grade glioma in children.
    Journal of neuro-oncology, 2006, Volume: 76, Issue:3

    Topics: Adolescent; Adult; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Phytogenic; Brain Neopl

2006
Temozolomide after radiotherapy for newly diagnosed high-grade glioma and unfavorable low-grade glioma in children.
    Journal of neuro-oncology, 2006, Volume: 76, Issue:3

    Topics: Adolescent; Adult; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Phytogenic; Brain Neopl

2006
Temozolomide after radiotherapy for newly diagnosed high-grade glioma and unfavorable low-grade glioma in children.
    Journal of neuro-oncology, 2006, Volume: 76, Issue:3

    Topics: Adolescent; Adult; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Phytogenic; Brain Neopl

2006
Temozolomide after radiotherapy for newly diagnosed high-grade glioma and unfavorable low-grade glioma in children.
    Journal of neuro-oncology, 2006, Volume: 76, Issue:3

    Topics: Adolescent; Adult; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Phytogenic; Brain Neopl

2006
Temozolomide after radiotherapy for newly diagnosed high-grade glioma and unfavorable low-grade glioma in children.
    Journal of neuro-oncology, 2006, Volume: 76, Issue:3

    Topics: Adolescent; Adult; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Phytogenic; Brain Neopl

2006
Temozolomide after radiotherapy for newly diagnosed high-grade glioma and unfavorable low-grade glioma in children.
    Journal of neuro-oncology, 2006, Volume: 76, Issue:3

    Topics: Adolescent; Adult; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Phytogenic; Brain Neopl

2006
Temozolomide after radiotherapy for newly diagnosed high-grade glioma and unfavorable low-grade glioma in children.
    Journal of neuro-oncology, 2006, Volume: 76, Issue:3

    Topics: Adolescent; Adult; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Phytogenic; Brain Neopl

2006
Temozolomide after radiotherapy for newly diagnosed high-grade glioma and unfavorable low-grade glioma in children.
    Journal of neuro-oncology, 2006, Volume: 76, Issue:3

    Topics: Adolescent; Adult; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Phytogenic; Brain Neopl

2006
Temozolomide after radiotherapy for newly diagnosed high-grade glioma and unfavorable low-grade glioma in children.
    Journal of neuro-oncology, 2006, Volume: 76, Issue:3

    Topics: Adolescent; Adult; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Phytogenic; Brain Neopl

2006
Temozolomide after radiotherapy for newly diagnosed high-grade glioma and unfavorable low-grade glioma in children.
    Journal of neuro-oncology, 2006, Volume: 76, Issue:3

    Topics: Adolescent; Adult; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Phytogenic; Brain Neopl

2006
Temozolomide after radiotherapy for newly diagnosed high-grade glioma and unfavorable low-grade glioma in children.
    Journal of neuro-oncology, 2006, Volume: 76, Issue:3

    Topics: Adolescent; Adult; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Phytogenic; Brain Neopl

2006
Temozolomide after radiotherapy for newly diagnosed high-grade glioma and unfavorable low-grade glioma in children.
    Journal of neuro-oncology, 2006, Volume: 76, Issue:3

    Topics: Adolescent; Adult; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Phytogenic; Brain Neopl

2006
Food and Drug Administration Drug approval summary: temozolomide plus radiation therapy for the treatment of newly diagnosed glioblastoma multiforme.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2005, Oct-01, Volume: 11, Issue:19 Pt 1

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant; Combined Mo

2005
Food and Drug Administration Drug approval summary: temozolomide plus radiation therapy for the treatment of newly diagnosed glioblastoma multiforme.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2005, Oct-01, Volume: 11, Issue:19 Pt 1

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant; Combined Mo

2005
Food and Drug Administration Drug approval summary: temozolomide plus radiation therapy for the treatment of newly diagnosed glioblastoma multiforme.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2005, Oct-01, Volume: 11, Issue:19 Pt 1

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant; Combined Mo

2005
Perfusion and diffusion MRI of glioblastoma progression in a four-year prospective temozolomide clinical trial.
    International journal of radiation oncology, biology, physics, 2006, Mar-01, Volume: 64, Issue:3

    Topics: Analysis of Variance; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Diffusion Mag

2006
Perfusion and diffusion MRI of glioblastoma progression in a four-year prospective temozolomide clinical trial.
    International journal of radiation oncology, biology, physics, 2006, Mar-01, Volume: 64, Issue:3

    Topics: Analysis of Variance; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Diffusion Mag

2006
Perfusion and diffusion MRI of glioblastoma progression in a four-year prospective temozolomide clinical trial.
    International journal of radiation oncology, biology, physics, 2006, Mar-01, Volume: 64, Issue:3

    Topics: Analysis of Variance; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Diffusion Mag

2006
Phase II trial of temozolomide in children with recurrent high-grade glioma.
    Journal of neuro-oncology, 2006, Volume: 77, Issue:1

    Topics: Adolescent; Antineoplastic Agents, Alkylating; Bone Marrow; Brain Neoplasms; Child; Child, Preschool

2006
Phase II trial of temozolomide in children with recurrent high-grade glioma.
    Journal of neuro-oncology, 2006, Volume: 77, Issue:1

    Topics: Adolescent; Antineoplastic Agents, Alkylating; Bone Marrow; Brain Neoplasms; Child; Child, Preschool

2006
Phase II trial of temozolomide in children with recurrent high-grade glioma.
    Journal of neuro-oncology, 2006, Volume: 77, Issue:1

    Topics: Adolescent; Antineoplastic Agents, Alkylating; Bone Marrow; Brain Neoplasms; Child; Child, Preschool

2006
Health-related quality of life in patients with glioblastoma: a randomised controlled trial.
    The Lancet. Oncology, 2005, Volume: 6, Issue:12

    Topics: Activities of Daily Living; Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neopla

2005
Health-related quality of life in patients with glioblastoma: a randomised controlled trial.
    The Lancet. Oncology, 2005, Volume: 6, Issue:12

    Topics: Activities of Daily Living; Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neopla

2005
Health-related quality of life in patients with glioblastoma: a randomised controlled trial.
    The Lancet. Oncology, 2005, Volume: 6, Issue:12

    Topics: Activities of Daily Living; Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neopla

2005
Health-related quality of life in patients with glioblastoma: a randomised controlled trial.
    The Lancet. Oncology, 2005, Volume: 6, Issue:12

    Topics: Activities of Daily Living; Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neopla

2005
Health-related quality of life in patients with glioblastoma: a randomised controlled trial.
    The Lancet. Oncology, 2005, Volume: 6, Issue:12

    Topics: Activities of Daily Living; Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neopla

2005
Health-related quality of life in patients with glioblastoma: a randomised controlled trial.
    The Lancet. Oncology, 2005, Volume: 6, Issue:12

    Topics: Activities of Daily Living; Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neopla

2005
Health-related quality of life in patients with glioblastoma: a randomised controlled trial.
    The Lancet. Oncology, 2005, Volume: 6, Issue:12

    Topics: Activities of Daily Living; Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neopla

2005
Health-related quality of life in patients with glioblastoma: a randomised controlled trial.
    The Lancet. Oncology, 2005, Volume: 6, Issue:12

    Topics: Activities of Daily Living; Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neopla

2005
Health-related quality of life in patients with glioblastoma: a randomised controlled trial.
    The Lancet. Oncology, 2005, Volume: 6, Issue:12

    Topics: Activities of Daily Living; Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neopla

2005
Health-related quality of life in patients with glioblastoma: a randomised controlled trial.
    The Lancet. Oncology, 2005, Volume: 6, Issue:12

    Topics: Activities of Daily Living; Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neopla

2005
Health-related quality of life in patients with glioblastoma: a randomised controlled trial.
    The Lancet. Oncology, 2005, Volume: 6, Issue:12

    Topics: Activities of Daily Living; Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neopla

2005
Health-related quality of life in patients with glioblastoma: a randomised controlled trial.
    The Lancet. Oncology, 2005, Volume: 6, Issue:12

    Topics: Activities of Daily Living; Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neopla

2005
Salvage chemotherapy with cyclophosphamide for recurrent temozolomide-refractory anaplastic astrocytoma.
    Cancer, 2006, Jan-01, Volume: 106, Issue:1

    Topics: Adult; Anaplasia; Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neoplasms; Cyclophosphamide;

2006
Salvage chemotherapy with cyclophosphamide for recurrent temozolomide-refractory anaplastic astrocytoma.
    Cancer, 2006, Jan-01, Volume: 106, Issue:1

    Topics: Adult; Anaplasia; Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neoplasms; Cyclophosphamide;

2006
Salvage chemotherapy with cyclophosphamide for recurrent temozolomide-refractory anaplastic astrocytoma.
    Cancer, 2006, Jan-01, Volume: 106, Issue:1

    Topics: Adult; Anaplasia; Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neoplasms; Cyclophosphamide;

2006
Temozolomide in the treatment of recurrent malignant glioma in Chinese patients.
    Hong Kong medical journal = Xianggang yi xue za zhi, 2005, Volume: 11, Issue:6

    Topics: Adolescent; Adult; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Drug Administrat

2005
Temozolomide in the treatment of recurrent malignant glioma in Chinese patients.
    Hong Kong medical journal = Xianggang yi xue za zhi, 2005, Volume: 11, Issue:6

    Topics: Adolescent; Adult; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Drug Administrat

2005
Temozolomide in the treatment of recurrent malignant glioma in Chinese patients.
    Hong Kong medical journal = Xianggang yi xue za zhi, 2005, Volume: 11, Issue:6

    Topics: Adolescent; Adult; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Drug Administrat

2005
Surgery, radiotherapy and temozolomide in treating high-grade gliomas.
    Frontiers in bioscience : a journal and virtual library, 2006, May-01, Volume: 11

    Topics: Adult; Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neoplasms; Clinical Trials as Topic; Co

2006
Surgery, radiotherapy and temozolomide in treating high-grade gliomas.
    Frontiers in bioscience : a journal and virtual library, 2006, May-01, Volume: 11

    Topics: Adult; Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neoplasms; Clinical Trials as Topic; Co

2006
Surgery, radiotherapy and temozolomide in treating high-grade gliomas.
    Frontiers in bioscience : a journal and virtual library, 2006, May-01, Volume: 11

    Topics: Adult; Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neoplasms; Clinical Trials as Topic; Co

2006
A biochemotherapy regimen with concurrent administration of cisplatin, vinblastine, temozolomide (Temodal), interferon-alfa and interleukin-2 for metastatic melanoma: a phase II study.
    Melanoma research, 2006, Volume: 16, Issue:1

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Cisplatin; Dacarbazine

2006
A biochemotherapy regimen with concurrent administration of cisplatin, vinblastine, temozolomide (Temodal), interferon-alfa and interleukin-2 for metastatic melanoma: a phase II study.
    Melanoma research, 2006, Volume: 16, Issue:1

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Cisplatin; Dacarbazine

2006
A biochemotherapy regimen with concurrent administration of cisplatin, vinblastine, temozolomide (Temodal), interferon-alfa and interleukin-2 for metastatic melanoma: a phase II study.
    Melanoma research, 2006, Volume: 16, Issue:1

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Cisplatin; Dacarbazine

2006
Phase 1 study of erlotinib HCl alone and combined with temozolomide in patients with stable or recurrent malignant glioma.
    Neuro-oncology, 2006, Volume: 8, Issue:1

    Topics: Adult; Aged; Anticonvulsants; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Dacar

2006
Phase 1 study of erlotinib HCl alone and combined with temozolomide in patients with stable or recurrent malignant glioma.
    Neuro-oncology, 2006, Volume: 8, Issue:1

    Topics: Adult; Aged; Anticonvulsants; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Dacar

2006
Phase 1 study of erlotinib HCl alone and combined with temozolomide in patients with stable or recurrent malignant glioma.
    Neuro-oncology, 2006, Volume: 8, Issue:1

    Topics: Adult; Aged; Anticonvulsants; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Dacar

2006
Vinorelbine combined with a protracted course of temozolomide for recurrent brain metastases: a phase I trial.
    Journal of neuro-oncology, 2006, Volume: 78, Issue:3

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Phytogenic; Antineoplastic Co

2006
Vinorelbine combined with a protracted course of temozolomide for recurrent brain metastases: a phase I trial.
    Journal of neuro-oncology, 2006, Volume: 78, Issue:3

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Phytogenic; Antineoplastic Co

2006
Vinorelbine combined with a protracted course of temozolomide for recurrent brain metastases: a phase I trial.
    Journal of neuro-oncology, 2006, Volume: 78, Issue:3

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Phytogenic; Antineoplastic Co

2006
Phase II trial of temozolomide plus marimastat for recurrent anaplastic gliomas: a relationship among efficacy, joint toxicity and anticonvulsant status.
    Journal of neuro-oncology, 2006, Volume: 80, Issue:1

    Topics: Anticonvulsants; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Cytochrome P-450 E

2006
Phase II trial of temozolomide plus marimastat for recurrent anaplastic gliomas: a relationship among efficacy, joint toxicity and anticonvulsant status.
    Journal of neuro-oncology, 2006, Volume: 80, Issue:1

    Topics: Anticonvulsants; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Cytochrome P-450 E

2006
Phase II trial of temozolomide plus marimastat for recurrent anaplastic gliomas: a relationship among efficacy, joint toxicity and anticonvulsant status.
    Journal of neuro-oncology, 2006, Volume: 80, Issue:1

    Topics: Anticonvulsants; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Cytochrome P-450 E

2006
Treatment of primary glioblastoma multiforme with cetuximab, radiotherapy and temozolomide (GERT)--phase I/II trial: study protocol.
    BMC cancer, 2006, May-18, Volume: 6

    Topics: Adolescent; Adult; Aged; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic C

2006
Treatment of primary glioblastoma multiforme with cetuximab, radiotherapy and temozolomide (GERT)--phase I/II trial: study protocol.
    BMC cancer, 2006, May-18, Volume: 6

    Topics: Adolescent; Adult; Aged; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic C

2006
Treatment of primary glioblastoma multiforme with cetuximab, radiotherapy and temozolomide (GERT)--phase I/II trial: study protocol.
    BMC cancer, 2006, May-18, Volume: 6

    Topics: Adolescent; Adult; Aged; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic C

2006
Adding concomitant and adjuvant temozolomide to radiotherapy does not reduce health-related quality of life in people with glioblastoma.
    Cancer treatment reviews, 2006, Volume: 32, Issue:6

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant; Combined Modality Therap

2006
Adding concomitant and adjuvant temozolomide to radiotherapy does not reduce health-related quality of life in people with glioblastoma.
    Cancer treatment reviews, 2006, Volume: 32, Issue:6

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant; Combined Modality Therap

2006
Adding concomitant and adjuvant temozolomide to radiotherapy does not reduce health-related quality of life in people with glioblastoma.
    Cancer treatment reviews, 2006, Volume: 32, Issue:6

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant; Combined Modality Therap

2006
Radiotherapy and temozolomide for newly diagnosed glioblastoma: recursive partitioning analysis of the EORTC 26981/22981-NCIC CE3 phase III randomized trial.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2006, Jun-01, Volume: 24, Issue:16

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Chemotherapy, Adjuvant; Dac

2006
Radiotherapy and temozolomide for newly diagnosed glioblastoma: recursive partitioning analysis of the EORTC 26981/22981-NCIC CE3 phase III randomized trial.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2006, Jun-01, Volume: 24, Issue:16

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Chemotherapy, Adjuvant; Dac

2006
Radiotherapy and temozolomide for newly diagnosed glioblastoma: recursive partitioning analysis of the EORTC 26981/22981-NCIC CE3 phase III randomized trial.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2006, Jun-01, Volume: 24, Issue:16

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Chemotherapy, Adjuvant; Dac

2006
New approach in delivering chemotherapy: locoregional treatment for recurrent glioblastoma (rGBM).
    Journal of experimental & clinical cancer research : CR, 2003, Volume: 22, Issue:4 Suppl

    Topics: Antineoplastic Agents; Brain Neoplasms; Chemotherapy, Cancer, Regional Perfusion; Combined Modality

2003
New approach in delivering chemotherapy: locoregional treatment for recurrent glioblastoma (rGBM).
    Journal of experimental & clinical cancer research : CR, 2003, Volume: 22, Issue:4 Suppl

    Topics: Antineoplastic Agents; Brain Neoplasms; Chemotherapy, Cancer, Regional Perfusion; Combined Modality

2003
New approach in delivering chemotherapy: locoregional treatment for recurrent glioblastoma (rGBM).
    Journal of experimental & clinical cancer research : CR, 2003, Volume: 22, Issue:4 Suppl

    Topics: Antineoplastic Agents; Brain Neoplasms; Chemotherapy, Cancer, Regional Perfusion; Combined Modality

2003
Phase II trial of temozolomide and cisplatin followed by whole brain radiotherapy in non-small-cell lung cancer patients with brain metastases: a GLOT-GFPC study.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2006, Volume: 17, Issue:9

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carcinoma, Non-Small-C

2006
Phase II trial of temozolomide and cisplatin followed by whole brain radiotherapy in non-small-cell lung cancer patients with brain metastases: a GLOT-GFPC study.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2006, Volume: 17, Issue:9

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carcinoma, Non-Small-C

2006
Phase II trial of temozolomide and cisplatin followed by whole brain radiotherapy in non-small-cell lung cancer patients with brain metastases: a GLOT-GFPC study.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2006, Volume: 17, Issue:9

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carcinoma, Non-Small-C

2006
Temozolomide for recurrent or progressive high-grade malignant glioma: results of an Austrian multicenter observational study.
    Wiener klinische Wochenschrift, 2006, Volume: 118, Issue:7-8

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Austria; Brain Neoplasms; Dacarbazine; F

2006
Temozolomide for recurrent or progressive high-grade malignant glioma: results of an Austrian multicenter observational study.
    Wiener klinische Wochenschrift, 2006, Volume: 118, Issue:7-8

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Austria; Brain Neoplasms; Dacarbazine; F

2006
Temozolomide for recurrent or progressive high-grade malignant glioma: results of an Austrian multicenter observational study.
    Wiener klinische Wochenschrift, 2006, Volume: 118, Issue:7-8

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Austria; Brain Neoplasms; Dacarbazine; F

2006
MR-guided laser-induced interstitial thermotherapy of recurrent glioblastoma multiforme: preliminary results in 16 patients.
    European journal of radiology, 2006, Volume: 59, Issue:2

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbaz

2006
MR-guided laser-induced interstitial thermotherapy of recurrent glioblastoma multiforme: preliminary results in 16 patients.
    European journal of radiology, 2006, Volume: 59, Issue:2

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbaz

2006
MR-guided laser-induced interstitial thermotherapy of recurrent glioblastoma multiforme: preliminary results in 16 patients.
    European journal of radiology, 2006, Volume: 59, Issue:2

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbaz

2006
Temozolomide treatment for newly diagnosed anaplastic oligodendrogliomas: a clinical efficacy trial.
    Journal of neuro-oncology, 2006, Volume: 79, Issue:2

    Topics: Adult; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Disease-Free Survival; Drug

2006
Temozolomide treatment for newly diagnosed anaplastic oligodendrogliomas: a clinical efficacy trial.
    Journal of neuro-oncology, 2006, Volume: 79, Issue:2

    Topics: Adult; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Disease-Free Survival; Drug

2006
Temozolomide treatment for newly diagnosed anaplastic oligodendrogliomas: a clinical efficacy trial.
    Journal of neuro-oncology, 2006, Volume: 79, Issue:2

    Topics: Adult; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Disease-Free Survival; Drug

2006
Temozolomide chemotherapy in patients with recurrent malignant gliomas.
    Journal of Korean medical science, 2006, Volume: 21, Issue:4

    Topics: Administration, Oral; Adolescent; Adult; Antineoplastic Agents, Alkylating; Brain; Brain Neoplasms;

2006
Temozolomide chemotherapy in patients with recurrent malignant gliomas.
    Journal of Korean medical science, 2006, Volume: 21, Issue:4

    Topics: Administration, Oral; Adolescent; Adult; Antineoplastic Agents, Alkylating; Brain; Brain Neoplasms;

2006
Temozolomide chemotherapy in patients with recurrent malignant gliomas.
    Journal of Korean medical science, 2006, Volume: 21, Issue:4

    Topics: Administration, Oral; Adolescent; Adult; Antineoplastic Agents, Alkylating; Brain; Brain Neoplasms;

2006
Safety and pharmacokinetics of temozolomide using a dose-escalation, metronomic schedule in recurrent paediatric brain tumours.
    European journal of cancer (Oxford, England : 1990), 2006, Volume: 42, Issue:14

    Topics: Administration, Oral; Antineoplastic Agents, Alkylating; Brain Neoplasms; Child; Dacarbazine; Dose-R

2006
Safety and pharmacokinetics of temozolomide using a dose-escalation, metronomic schedule in recurrent paediatric brain tumours.
    European journal of cancer (Oxford, England : 1990), 2006, Volume: 42, Issue:14

    Topics: Administration, Oral; Antineoplastic Agents, Alkylating; Brain Neoplasms; Child; Dacarbazine; Dose-R

2006
Safety and pharmacokinetics of temozolomide using a dose-escalation, metronomic schedule in recurrent paediatric brain tumours.
    European journal of cancer (Oxford, England : 1990), 2006, Volume: 42, Issue:14

    Topics: Administration, Oral; Antineoplastic Agents, Alkylating; Brain Neoplasms; Child; Dacarbazine; Dose-R

2006
Phase I study of capecitabine in combination with temozolomide in the treatment of patients with brain metastases from breast carcinoma.
    Cancer, 2006, Sep-15, Volume: 107, Issue:6

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Breast Neoplasms; Cape

2006
Phase I study of capecitabine in combination with temozolomide in the treatment of patients with brain metastases from breast carcinoma.
    Cancer, 2006, Sep-15, Volume: 107, Issue:6

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Breast Neoplasms; Cape

2006
Phase I study of capecitabine in combination with temozolomide in the treatment of patients with brain metastases from breast carcinoma.
    Cancer, 2006, Sep-15, Volume: 107, Issue:6

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Breast Neoplasms; Cape

2006
Early necrosis following concurrent Temodar and radiotherapy in patients with glioblastoma.
    Journal of neuro-oncology, 2007, Volume: 82, Issue:1

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant; Combined Mo

2007
Early necrosis following concurrent Temodar and radiotherapy in patients with glioblastoma.
    Journal of neuro-oncology, 2007, Volume: 82, Issue:1

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant; Combined Mo

2007
Early necrosis following concurrent Temodar and radiotherapy in patients with glioblastoma.
    Journal of neuro-oncology, 2007, Volume: 82, Issue:1

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant; Combined Mo

2007
Correlations between O6-methylguanine DNA methyltransferase promoter methylation status, 1p and 19q deletions, and response to temozolomide in anaplastic and recurrent oligodendroglioma: a prospective GICNO study.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2006, Oct-10, Volume: 24, Issue:29

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chromosome Deletion; Ch

2006
Correlations between O6-methylguanine DNA methyltransferase promoter methylation status, 1p and 19q deletions, and response to temozolomide in anaplastic and recurrent oligodendroglioma: a prospective GICNO study.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2006, Oct-10, Volume: 24, Issue:29

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chromosome Deletion; Ch

2006
Correlations between O6-methylguanine DNA methyltransferase promoter methylation status, 1p and 19q deletions, and response to temozolomide in anaplastic and recurrent oligodendroglioma: a prospective GICNO study.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2006, Oct-10, Volume: 24, Issue:29

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chromosome Deletion; Ch

2006
[Efficacy and safety of monotherapy with temozolomide in patients with anaplastic astrocytoma at first relapse--a phase II clinical study].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2006, Volume: 33, Issue:9

    Topics: Adult; Aged; Anorexia; Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neoplasms; Dacarbazine;

2006
[Efficacy and safety of monotherapy with temozolomide in patients with anaplastic astrocytoma at first relapse--a phase II clinical study].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2006, Volume: 33, Issue:9

    Topics: Adult; Aged; Anorexia; Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neoplasms; Dacarbazine;

2006
[Efficacy and safety of monotherapy with temozolomide in patients with anaplastic astrocytoma at first relapse--a phase II clinical study].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2006, Volume: 33, Issue:9

    Topics: Adult; Aged; Anorexia; Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neoplasms; Dacarbazine;

2006
Temozolomide in combination with celecoxib in patients with advanced melanoma. A phase II study of the Hellenic Cooperative Oncology Group.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2006, Volume: 17, Issue:12

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Celecoxib; Cyclooxygenase 2; Cyclooxygenase Inhi

2006
Temozolomide in combination with celecoxib in patients with advanced melanoma. A phase II study of the Hellenic Cooperative Oncology Group.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2006, Volume: 17, Issue:12

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Celecoxib; Cyclooxygenase 2; Cyclooxygenase Inhi

2006
Temozolomide in combination with celecoxib in patients with advanced melanoma. A phase II study of the Hellenic Cooperative Oncology Group.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2006, Volume: 17, Issue:12

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Celecoxib; Cyclooxygenase 2; Cyclooxygenase Inhi

2006
Phase II trial of lomustine plus temozolomide chemotherapy in addition to radiotherapy in newly diagnosed glioblastoma: UKT-03.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2006, Sep-20, Volume: 24, Issue:27

    Topics: Administration, Oral; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms;

2006
Phase II trial of lomustine plus temozolomide chemotherapy in addition to radiotherapy in newly diagnosed glioblastoma: UKT-03.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2006, Sep-20, Volume: 24, Issue:27

    Topics: Administration, Oral; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms;

2006
Phase II trial of lomustine plus temozolomide chemotherapy in addition to radiotherapy in newly diagnosed glioblastoma: UKT-03.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2006, Sep-20, Volume: 24, Issue:27

    Topics: Administration, Oral; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms;

2006
Phase II study of temozolomide and thalidomide in patients with metastatic melanoma in the brain: high rate of thromboembolic events (CALGB 500102).
    Cancer, 2006, Oct-15, Volume: 107, Issue:8

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Dac

2006
Phase II study of temozolomide and thalidomide in patients with metastatic melanoma in the brain: high rate of thromboembolic events (CALGB 500102).
    Cancer, 2006, Oct-15, Volume: 107, Issue:8

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Dac

2006
Phase II study of temozolomide and thalidomide in patients with metastatic melanoma in the brain: high rate of thromboembolic events (CALGB 500102).
    Cancer, 2006, Oct-15, Volume: 107, Issue:8

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Dac

2006
Dose-intensified bi-weekly temozolomide in patients with asymptomatic brain metastases from malignant melanoma: a phase II DeCOG/ADO study.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2006, Volume: 17, Issue:10

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Dose-Response Relation

2006
Dose-intensified bi-weekly temozolomide in patients with asymptomatic brain metastases from malignant melanoma: a phase II DeCOG/ADO study.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2006, Volume: 17, Issue:10

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Dose-Response Relation

2006
Dose-intensified bi-weekly temozolomide in patients with asymptomatic brain metastases from malignant melanoma: a phase II DeCOG/ADO study.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2006, Volume: 17, Issue:10

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Dose-Response Relation

2006
A pilot study of metronomic temozolomide treatment in patients with recurrent temozolomide-refractory glioblastoma.
    Oncology reports, 2006, Volume: 16, Issue:5

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Dose-Response Relation

2006
A pilot study of metronomic temozolomide treatment in patients with recurrent temozolomide-refractory glioblastoma.
    Oncology reports, 2006, Volume: 16, Issue:5

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Dose-Response Relation

2006
A pilot study of metronomic temozolomide treatment in patients with recurrent temozolomide-refractory glioblastoma.
    Oncology reports, 2006, Volume: 16, Issue:5

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Dose-Response Relation

2006
Temozolomide 3 weeks on and 1 week off as first-line therapy for recurrent glioblastoma: phase II study from gruppo italiano cooperativo di neuro-oncologia (GICNO).
    British journal of cancer, 2006, Nov-06, Volume: 95, Issue:9

    Topics: Adult; Aged; Anemia; Antineoplastic Agents, Alkylating; Brain Neoplasms; Constipation; Dacarbazine;

2006
Temozolomide 3 weeks on and 1 week off as first-line therapy for recurrent glioblastoma: phase II study from gruppo italiano cooperativo di neuro-oncologia (GICNO).
    British journal of cancer, 2006, Nov-06, Volume: 95, Issue:9

    Topics: Adult; Aged; Anemia; Antineoplastic Agents, Alkylating; Brain Neoplasms; Constipation; Dacarbazine;

2006
Temozolomide 3 weeks on and 1 week off as first-line therapy for recurrent glioblastoma: phase II study from gruppo italiano cooperativo di neuro-oncologia (GICNO).
    British journal of cancer, 2006, Nov-06, Volume: 95, Issue:9

    Topics: Adult; Aged; Anemia; Antineoplastic Agents, Alkylating; Brain Neoplasms; Constipation; Dacarbazine;

2006
Administration of temozolomide during and after radiotherapy for newly diagnosed high-grade gliomas excluding glioblastoma multiforme.
    Journal of neuro-oncology, 2007, Volume: 81, Issue:3

    Topics: Antineoplastic Agents; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Glioma; Humans; Surv

2007
Administration of temozolomide during and after radiotherapy for newly diagnosed high-grade gliomas excluding glioblastoma multiforme.
    Journal of neuro-oncology, 2007, Volume: 81, Issue:3

    Topics: Antineoplastic Agents; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Glioma; Humans; Surv

2007
Administration of temozolomide during and after radiotherapy for newly diagnosed high-grade gliomas excluding glioblastoma multiforme.
    Journal of neuro-oncology, 2007, Volume: 81, Issue:3

    Topics: Antineoplastic Agents; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Glioma; Humans; Surv

2007
A North American brain tumor consortium (NABTC 99-04) phase II trial of temozolomide plus thalidomide for recurrent glioblastoma multiforme.
    Journal of neuro-oncology, 2007, Volume: 81, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Dac

2007
A North American brain tumor consortium (NABTC 99-04) phase II trial of temozolomide plus thalidomide for recurrent glioblastoma multiforme.
    Journal of neuro-oncology, 2007, Volume: 81, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Dac

2007
A North American brain tumor consortium (NABTC 99-04) phase II trial of temozolomide plus thalidomide for recurrent glioblastoma multiforme.
    Journal of neuro-oncology, 2007, Volume: 81, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Dac

2007
A phase I/II study of lomustine and temozolomide in patients with cerebral metastases from malignant melanoma.
    British journal of cancer, 2007, Jan-15, Volume: 96, Issue:1

    Topics: Administration, Oral; Adult; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Dacarb

2007
A phase I/II study of lomustine and temozolomide in patients with cerebral metastases from malignant melanoma.
    British journal of cancer, 2007, Jan-15, Volume: 96, Issue:1

    Topics: Administration, Oral; Adult; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Dacarb

2007
A phase I/II study of lomustine and temozolomide in patients with cerebral metastases from malignant melanoma.
    British journal of cancer, 2007, Jan-15, Volume: 96, Issue:1

    Topics: Administration, Oral; Adult; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Dacarb

2007
[Temozolomide in the treatment of recurrent malignant glioma].
    No shinkei geka. Neurological surgery, 2006, Volume: 34, Issue:12

    Topics: Administration, Oral; Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; D

2006
[Temozolomide in the treatment of recurrent malignant glioma].
    No shinkei geka. Neurological surgery, 2006, Volume: 34, Issue:12

    Topics: Administration, Oral; Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; D

2006
[Temozolomide in the treatment of recurrent malignant glioma].
    No shinkei geka. Neurological surgery, 2006, Volume: 34, Issue:12

    Topics: Administration, Oral; Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; D

2006
MGMT methylation: a marker of response to temozolomide in low-grade gliomas.
    Annals of neurology, 2006, Volume: 60, Issue:6

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Biomarkers, Tumor; Brain Neoplasms; Dacarbazine; Dis

2006
MGMT methylation: a marker of response to temozolomide in low-grade gliomas.
    Annals of neurology, 2006, Volume: 60, Issue:6

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Biomarkers, Tumor; Brain Neoplasms; Dacarbazine; Dis

2006
MGMT methylation: a marker of response to temozolomide in low-grade gliomas.
    Annals of neurology, 2006, Volume: 60, Issue:6

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Biomarkers, Tumor; Brain Neoplasms; Dacarbazine; Dis

2006
Concomitant treatment of brain metastasis with whole brain radiotherapy [WBRT] and temozolomide [TMZ] is active and improves quality of life.
    BMC cancer, 2007, Jan-25, Volume: 7

    Topics: Aged; Brain; Brain Neoplasms; Combined Modality Therapy; Cranial Irradiation; Dacarbazine; Female; H

2007
Concomitant treatment of brain metastasis with whole brain radiotherapy [WBRT] and temozolomide [TMZ] is active and improves quality of life.
    BMC cancer, 2007, Jan-25, Volume: 7

    Topics: Aged; Brain; Brain Neoplasms; Combined Modality Therapy; Cranial Irradiation; Dacarbazine; Female; H

2007
Concomitant treatment of brain metastasis with whole brain radiotherapy [WBRT] and temozolomide [TMZ] is active and improves quality of life.
    BMC cancer, 2007, Jan-25, Volume: 7

    Topics: Aged; Brain; Brain Neoplasms; Combined Modality Therapy; Cranial Irradiation; Dacarbazine; Female; H

2007
Estimation of radiobiologic parameters and equivalent radiation dose of cytotoxic chemotherapy in malignant glioma.
    International journal of radiation oncology, biology, physics, 2007, Jun-01, Volume: 68, Issue:2

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Division; Dacarbazine; Glioma; Humans; Mont

2007
Estimation of radiobiologic parameters and equivalent radiation dose of cytotoxic chemotherapy in malignant glioma.
    International journal of radiation oncology, biology, physics, 2007, Jun-01, Volume: 68, Issue:2

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Division; Dacarbazine; Glioma; Humans; Mont

2007
Estimation of radiobiologic parameters and equivalent radiation dose of cytotoxic chemotherapy in malignant glioma.
    International journal of radiation oncology, biology, physics, 2007, Jun-01, Volume: 68, Issue:2

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Division; Dacarbazine; Glioma; Humans; Mont

2007
Safety and feasibility of long-term temozolomide treatment in patients with high-grade glioma.
    Neurology, 2007, Feb-27, Volume: 68, Issue:9

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Disease-Fr

2007
Safety and feasibility of long-term temozolomide treatment in patients with high-grade glioma.
    Neurology, 2007, Feb-27, Volume: 68, Issue:9

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Disease-Fr

2007
Safety and feasibility of long-term temozolomide treatment in patients with high-grade glioma.
    Neurology, 2007, Feb-27, Volume: 68, Issue:9

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Disease-Fr

2007
Temozolomide as salvage treatment in primary brain lymphomas.
    British journal of cancer, 2007, Mar-26, Volume: 96, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Fem

2007
Temozolomide as salvage treatment in primary brain lymphomas.
    British journal of cancer, 2007, Mar-26, Volume: 96, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Fem

2007
Temozolomide as salvage treatment in primary brain lymphomas.
    British journal of cancer, 2007, Mar-26, Volume: 96, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Fem

2007
Temozolomide as salvage treatment in primary brain lymphomas.
    British journal of cancer, 2007, Mar-26, Volume: 96, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Fem

2007
Temozolomide as salvage treatment in primary brain lymphomas.
    British journal of cancer, 2007, Mar-26, Volume: 96, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Fem

2007
Temozolomide as salvage treatment in primary brain lymphomas.
    British journal of cancer, 2007, Mar-26, Volume: 96, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Fem

2007
Temozolomide as salvage treatment in primary brain lymphomas.
    British journal of cancer, 2007, Mar-26, Volume: 96, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Fem

2007
Temozolomide as salvage treatment in primary brain lymphomas.
    British journal of cancer, 2007, Mar-26, Volume: 96, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Fem

2007
Temozolomide as salvage treatment in primary brain lymphomas.
    British journal of cancer, 2007, Mar-26, Volume: 96, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Fem

2007
Temozolomide as salvage treatment in primary brain lymphomas.
    British journal of cancer, 2007, Mar-26, Volume: 96, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Fem

2007
Temozolomide as salvage treatment in primary brain lymphomas.
    British journal of cancer, 2007, Mar-26, Volume: 96, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Fem

2007
Temozolomide as salvage treatment in primary brain lymphomas.
    British journal of cancer, 2007, Mar-26, Volume: 96, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Fem

2007
Temozolomide as salvage treatment in primary brain lymphomas.
    British journal of cancer, 2007, Mar-26, Volume: 96, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Fem

2007
Temozolomide as salvage treatment in primary brain lymphomas.
    British journal of cancer, 2007, Mar-26, Volume: 96, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Fem

2007
Temozolomide as salvage treatment in primary brain lymphomas.
    British journal of cancer, 2007, Mar-26, Volume: 96, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Fem

2007
Temozolomide as salvage treatment in primary brain lymphomas.
    British journal of cancer, 2007, Mar-26, Volume: 96, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Fem

2007
Temozolomide as salvage treatment in primary brain lymphomas.
    British journal of cancer, 2007, Mar-26, Volume: 96, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Fem

2007
Temozolomide as salvage treatment in primary brain lymphomas.
    British journal of cancer, 2007, Mar-26, Volume: 96, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Fem

2007
Temozolomide as salvage treatment in primary brain lymphomas.
    British journal of cancer, 2007, Mar-26, Volume: 96, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Fem

2007
Temozolomide as salvage treatment in primary brain lymphomas.
    British journal of cancer, 2007, Mar-26, Volume: 96, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Fem

2007
Temozolomide as salvage treatment in primary brain lymphomas.
    British journal of cancer, 2007, Mar-26, Volume: 96, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Fem

2007
Temozolomide as salvage treatment in primary brain lymphomas.
    British journal of cancer, 2007, Mar-26, Volume: 96, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Fem

2007
Temozolomide as salvage treatment in primary brain lymphomas.
    British journal of cancer, 2007, Mar-26, Volume: 96, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Fem

2007
Temozolomide as salvage treatment in primary brain lymphomas.
    British journal of cancer, 2007, Mar-26, Volume: 96, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Fem

2007
Temozolomide as salvage treatment in primary brain lymphomas.
    British journal of cancer, 2007, Mar-26, Volume: 96, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Fem

2007
Temozolomide as salvage treatment in primary brain lymphomas.
    British journal of cancer, 2007, Mar-26, Volume: 96, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Fem

2007
Temozolomide as salvage treatment in primary brain lymphomas.
    British journal of cancer, 2007, Mar-26, Volume: 96, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Fem

2007
Temozolomide as salvage treatment in primary brain lymphomas.
    British journal of cancer, 2007, Mar-26, Volume: 96, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Fem

2007
Temozolomide as salvage treatment in primary brain lymphomas.
    British journal of cancer, 2007, Mar-26, Volume: 96, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Fem

2007
Temozolomide as salvage treatment in primary brain lymphomas.
    British journal of cancer, 2007, Mar-26, Volume: 96, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Fem

2007
Temozolomide as salvage treatment in primary brain lymphomas.
    British journal of cancer, 2007, Mar-26, Volume: 96, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Fem

2007
Temozolomide as salvage treatment in primary brain lymphomas.
    British journal of cancer, 2007, Mar-26, Volume: 96, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Fem

2007
Temozolomide as salvage treatment in primary brain lymphomas.
    British journal of cancer, 2007, Mar-26, Volume: 96, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Fem

2007
Temozolomide as salvage treatment in primary brain lymphomas.
    British journal of cancer, 2007, Mar-26, Volume: 96, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Fem

2007
Temozolomide as salvage treatment in primary brain lymphomas.
    British journal of cancer, 2007, Mar-26, Volume: 96, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Fem

2007
Temozolomide as salvage treatment in primary brain lymphomas.
    British journal of cancer, 2007, Mar-26, Volume: 96, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Fem

2007
Temozolomide as salvage treatment in primary brain lymphomas.
    British journal of cancer, 2007, Mar-26, Volume: 96, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Fem

2007
Temozolomide as salvage treatment in primary brain lymphomas.
    British journal of cancer, 2007, Mar-26, Volume: 96, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Fem

2007
Temozolomide as salvage treatment in primary brain lymphomas.
    British journal of cancer, 2007, Mar-26, Volume: 96, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Fem

2007
Temozolomide as salvage treatment in primary brain lymphomas.
    British journal of cancer, 2007, Mar-26, Volume: 96, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Fem

2007
Temozolomide as salvage treatment in primary brain lymphomas.
    British journal of cancer, 2007, Mar-26, Volume: 96, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Fem

2007
Temozolomide as salvage treatment in primary brain lymphomas.
    British journal of cancer, 2007, Mar-26, Volume: 96, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Fem

2007
Temozolomide as salvage treatment in primary brain lymphomas.
    British journal of cancer, 2007, Mar-26, Volume: 96, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Fem

2007
Temozolomide as salvage treatment in primary brain lymphomas.
    British journal of cancer, 2007, Mar-26, Volume: 96, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Fem

2007
Temozolomide as salvage treatment in primary brain lymphomas.
    British journal of cancer, 2007, Mar-26, Volume: 96, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Fem

2007
Temozolomide as salvage treatment in primary brain lymphomas.
    British journal of cancer, 2007, Mar-26, Volume: 96, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Fem

2007
Temozolomide as salvage treatment in primary brain lymphomas.
    British journal of cancer, 2007, Mar-26, Volume: 96, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Fem

2007
Temozolomide as salvage treatment in primary brain lymphomas.
    British journal of cancer, 2007, Mar-26, Volume: 96, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Fem

2007
Temozolomide in children with progressive low-grade glioma.
    Neuro-oncology, 2007, Volume: 9, Issue:2

    Topics: Adolescent; Antineoplastic Agents, Alkylating; Brain Neoplasms; Child; Child, Preschool; Dacarbazine

2007
Temozolomide in children with progressive low-grade glioma.
    Neuro-oncology, 2007, Volume: 9, Issue:2

    Topics: Adolescent; Antineoplastic Agents, Alkylating; Brain Neoplasms; Child; Child, Preschool; Dacarbazine

2007
Temozolomide in children with progressive low-grade glioma.
    Neuro-oncology, 2007, Volume: 9, Issue:2

    Topics: Adolescent; Antineoplastic Agents, Alkylating; Brain Neoplasms; Child; Child, Preschool; Dacarbazine

2007
Temozolomide in glioblastoma: results of administration at first relapse and in newly diagnosed cases. Is still proposable an alternative schedule to concomitant protocol?
    Journal of neuro-oncology, 2007, Volume: 84, Issue:1

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Disease-Free Survival;

2007
Temozolomide in glioblastoma: results of administration at first relapse and in newly diagnosed cases. Is still proposable an alternative schedule to concomitant protocol?
    Journal of neuro-oncology, 2007, Volume: 84, Issue:1

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Disease-Free Survival;

2007
Temozolomide in glioblastoma: results of administration at first relapse and in newly diagnosed cases. Is still proposable an alternative schedule to concomitant protocol?
    Journal of neuro-oncology, 2007, Volume: 84, Issue:1

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Disease-Free Survival;

2007
Phase II trial of temozolomide and irinotecan as second-line treatment for advanced non-small cell lung cancer.
    Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer, 2006, Volume: 1, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Cam

2006
Phase II trial of temozolomide and irinotecan as second-line treatment for advanced non-small cell lung cancer.
    Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer, 2006, Volume: 1, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Cam

2006
Phase II trial of temozolomide and irinotecan as second-line treatment for advanced non-small cell lung cancer.
    Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer, 2006, Volume: 1, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Cam

2006
Correlation between O6-methylguanine-DNA methyltransferase and survival in inoperable newly diagnosed glioblastoma patients treated with neoadjuvant temozolomide.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2007, Apr-20, Volume: 25, Issue:12

    Topics: Adolescent; Adult; Aged; Biomarkers, Tumor; Brain Neoplasms; Chemotherapy, Adjuvant; Dacarbazine; Do

2007
Correlation between O6-methylguanine-DNA methyltransferase and survival in inoperable newly diagnosed glioblastoma patients treated with neoadjuvant temozolomide.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2007, Apr-20, Volume: 25, Issue:12

    Topics: Adolescent; Adult; Aged; Biomarkers, Tumor; Brain Neoplasms; Chemotherapy, Adjuvant; Dacarbazine; Do

2007
Correlation between O6-methylguanine-DNA methyltransferase and survival in inoperable newly diagnosed glioblastoma patients treated with neoadjuvant temozolomide.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2007, Apr-20, Volume: 25, Issue:12

    Topics: Adolescent; Adult; Aged; Biomarkers, Tumor; Brain Neoplasms; Chemotherapy, Adjuvant; Dacarbazine; Do

2007
Salvage chemotherapy with procarbazine and fotemustine combination in the treatment of temozolomide treated recurrent glioblastoma patients.
    Journal of neuro-oncology, 2008, Volume: 87, Issue:2

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Dacarbazine; Disease-F

2008
Salvage chemotherapy with procarbazine and fotemustine combination in the treatment of temozolomide treated recurrent glioblastoma patients.
    Journal of neuro-oncology, 2008, Volume: 87, Issue:2

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Dacarbazine; Disease-F

2008
Salvage chemotherapy with procarbazine and fotemustine combination in the treatment of temozolomide treated recurrent glioblastoma patients.
    Journal of neuro-oncology, 2008, Volume: 87, Issue:2

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Dacarbazine; Disease-F

2008
Phase II study of temozolomide and concomitant whole-brain radiotherapy in patients with brain metastases from solid tumors.
    Onkologie, 2007, Volume: 30, Issue:7

    Topics: Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Breast Neoplasms; Carci

2007
Phase II study of temozolomide and concomitant whole-brain radiotherapy in patients with brain metastases from solid tumors.
    Onkologie, 2007, Volume: 30, Issue:7

    Topics: Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Breast Neoplasms; Carci

2007
Phase II study of temozolomide and concomitant whole-brain radiotherapy in patients with brain metastases from solid tumors.
    Onkologie, 2007, Volume: 30, Issue:7

    Topics: Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Breast Neoplasms; Carci

2007
Efficacy and tolerability of temozolomide in an alternating weekly regimen in patients with recurrent glioma.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2007, Aug-01, Volume: 25, Issue:22

    Topics: Adult; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Disease Progression; DNA Met

2007
Efficacy and tolerability of temozolomide in an alternating weekly regimen in patients with recurrent glioma.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2007, Aug-01, Volume: 25, Issue:22

    Topics: Adult; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Disease Progression; DNA Met

2007
Efficacy and tolerability of temozolomide in an alternating weekly regimen in patients with recurrent glioma.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2007, Aug-01, Volume: 25, Issue:22

    Topics: Adult; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Disease Progression; DNA Met

2007
Phase-1 trial of gefitinib and temozolomide in patients with malignant glioma: a North American brain tumor consortium study.
    Cancer chemotherapy and pharmacology, 2008, Volume: 61, Issue:6

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Anti

2008
Phase-1 trial of gefitinib and temozolomide in patients with malignant glioma: a North American brain tumor consortium study.
    Cancer chemotherapy and pharmacology, 2008, Volume: 61, Issue:6

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Anti

2008
Phase-1 trial of gefitinib and temozolomide in patients with malignant glioma: a North American brain tumor consortium study.
    Cancer chemotherapy and pharmacology, 2008, Volume: 61, Issue:6

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Anti

2008
Phase 2 study of temozolomide in children and adolescents with recurrent central nervous system tumors: a report from the Children's Oncology Group.
    Cancer, 2007, Oct-01, Volume: 110, Issue:7

    Topics: Administration, Oral; Adolescent; Adult; Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neopl

2007
Phase 2 study of temozolomide in children and adolescents with recurrent central nervous system tumors: a report from the Children's Oncology Group.
    Cancer, 2007, Oct-01, Volume: 110, Issue:7

    Topics: Administration, Oral; Adolescent; Adult; Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neopl

2007
Phase 2 study of temozolomide in children and adolescents with recurrent central nervous system tumors: a report from the Children's Oncology Group.
    Cancer, 2007, Oct-01, Volume: 110, Issue:7

    Topics: Administration, Oral; Adolescent; Adult; Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neopl

2007
Phase 2 study of temozolomide in children and adolescents with recurrent central nervous system tumors: a report from the Children's Oncology Group.
    Cancer, 2007, Oct-01, Volume: 110, Issue:7

    Topics: Administration, Oral; Adolescent; Adult; Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neopl

2007
Phase 2 study of temozolomide in children and adolescents with recurrent central nervous system tumors: a report from the Children's Oncology Group.
    Cancer, 2007, Oct-01, Volume: 110, Issue:7

    Topics: Administration, Oral; Adolescent; Adult; Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neopl

2007
Phase 2 study of temozolomide in children and adolescents with recurrent central nervous system tumors: a report from the Children's Oncology Group.
    Cancer, 2007, Oct-01, Volume: 110, Issue:7

    Topics: Administration, Oral; Adolescent; Adult; Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neopl

2007
Phase 2 study of temozolomide in children and adolescents with recurrent central nervous system tumors: a report from the Children's Oncology Group.
    Cancer, 2007, Oct-01, Volume: 110, Issue:7

    Topics: Administration, Oral; Adolescent; Adult; Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neopl

2007
Phase 2 study of temozolomide in children and adolescents with recurrent central nervous system tumors: a report from the Children's Oncology Group.
    Cancer, 2007, Oct-01, Volume: 110, Issue:7

    Topics: Administration, Oral; Adolescent; Adult; Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neopl

2007
Phase 2 study of temozolomide in children and adolescents with recurrent central nervous system tumors: a report from the Children's Oncology Group.
    Cancer, 2007, Oct-01, Volume: 110, Issue:7

    Topics: Administration, Oral; Adolescent; Adult; Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neopl

2007
Phase 2 study of temozolomide in children and adolescents with recurrent central nervous system tumors: a report from the Children's Oncology Group.
    Cancer, 2007, Oct-01, Volume: 110, Issue:7

    Topics: Administration, Oral; Adolescent; Adult; Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neopl

2007
Phase 2 study of temozolomide in children and adolescents with recurrent central nervous system tumors: a report from the Children's Oncology Group.
    Cancer, 2007, Oct-01, Volume: 110, Issue:7

    Topics: Administration, Oral; Adolescent; Adult; Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neopl

2007
Phase 2 study of temozolomide in children and adolescents with recurrent central nervous system tumors: a report from the Children's Oncology Group.
    Cancer, 2007, Oct-01, Volume: 110, Issue:7

    Topics: Administration, Oral; Adolescent; Adult; Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neopl

2007
Phase 2 study of temozolomide in children and adolescents with recurrent central nervous system tumors: a report from the Children's Oncology Group.
    Cancer, 2007, Oct-01, Volume: 110, Issue:7

    Topics: Administration, Oral; Adolescent; Adult; Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neopl

2007
Phase 2 study of temozolomide in children and adolescents with recurrent central nervous system tumors: a report from the Children's Oncology Group.
    Cancer, 2007, Oct-01, Volume: 110, Issue:7

    Topics: Administration, Oral; Adolescent; Adult; Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neopl

2007
Phase 2 study of temozolomide in children and adolescents with recurrent central nervous system tumors: a report from the Children's Oncology Group.
    Cancer, 2007, Oct-01, Volume: 110, Issue:7

    Topics: Administration, Oral; Adolescent; Adult; Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neopl

2007
Phase 2 study of temozolomide in children and adolescents with recurrent central nervous system tumors: a report from the Children's Oncology Group.
    Cancer, 2007, Oct-01, Volume: 110, Issue:7

    Topics: Administration, Oral; Adolescent; Adult; Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neopl

2007
Phase 2 study of temozolomide in children and adolescents with recurrent central nervous system tumors: a report from the Children's Oncology Group.
    Cancer, 2007, Oct-01, Volume: 110, Issue:7

    Topics: Administration, Oral; Adolescent; Adult; Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neopl

2007
Phase 2 study of temozolomide in children and adolescents with recurrent central nervous system tumors: a report from the Children's Oncology Group.
    Cancer, 2007, Oct-01, Volume: 110, Issue:7

    Topics: Administration, Oral; Adolescent; Adult; Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neopl

2007
Phase 2 study of temozolomide in children and adolescents with recurrent central nervous system tumors: a report from the Children's Oncology Group.
    Cancer, 2007, Oct-01, Volume: 110, Issue:7

    Topics: Administration, Oral; Adolescent; Adult; Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neopl

2007
Phase 2 study of temozolomide in children and adolescents with recurrent central nervous system tumors: a report from the Children's Oncology Group.
    Cancer, 2007, Oct-01, Volume: 110, Issue:7

    Topics: Administration, Oral; Adolescent; Adult; Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neopl

2007
Phase 2 study of temozolomide in children and adolescents with recurrent central nervous system tumors: a report from the Children's Oncology Group.
    Cancer, 2007, Oct-01, Volume: 110, Issue:7

    Topics: Administration, Oral; Adolescent; Adult; Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neopl

2007
Phase 2 study of temozolomide in children and adolescents with recurrent central nervous system tumors: a report from the Children's Oncology Group.
    Cancer, 2007, Oct-01, Volume: 110, Issue:7

    Topics: Administration, Oral; Adolescent; Adult; Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neopl

2007
Phase 2 study of temozolomide in children and adolescents with recurrent central nervous system tumors: a report from the Children's Oncology Group.
    Cancer, 2007, Oct-01, Volume: 110, Issue:7

    Topics: Administration, Oral; Adolescent; Adult; Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neopl

2007
Phase 2 study of temozolomide in children and adolescents with recurrent central nervous system tumors: a report from the Children's Oncology Group.
    Cancer, 2007, Oct-01, Volume: 110, Issue:7

    Topics: Administration, Oral; Adolescent; Adult; Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neopl

2007
Phase 2 study of temozolomide in children and adolescents with recurrent central nervous system tumors: a report from the Children's Oncology Group.
    Cancer, 2007, Oct-01, Volume: 110, Issue:7

    Topics: Administration, Oral; Adolescent; Adult; Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neopl

2007
Phase 2 study of temozolomide in children and adolescents with recurrent central nervous system tumors: a report from the Children's Oncology Group.
    Cancer, 2007, Oct-01, Volume: 110, Issue:7

    Topics: Administration, Oral; Adolescent; Adult; Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neopl

2007
Phase 2 study of temozolomide in children and adolescents with recurrent central nervous system tumors: a report from the Children's Oncology Group.
    Cancer, 2007, Oct-01, Volume: 110, Issue:7

    Topics: Administration, Oral; Adolescent; Adult; Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neopl

2007
A phase II trial of vinorelbine and intensive temozolomide for patients with recurrent or progressive brain metastases.
    Journal of neuro-oncology, 2008, Volume: 87, Issue:1

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Dacarbazine; Disease-F

2008
A phase II trial of vinorelbine and intensive temozolomide for patients with recurrent or progressive brain metastases.
    Journal of neuro-oncology, 2008, Volume: 87, Issue:1

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Dacarbazine; Disease-F

2008
A phase II trial of vinorelbine and intensive temozolomide for patients with recurrent or progressive brain metastases.
    Journal of neuro-oncology, 2008, Volume: 87, Issue:1

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Dacarbazine; Disease-F

2008
Phase I trial of single-dose temozolomide and continuous administration of o6-benzylguanine in children with brain tumors: a pediatric brain tumor consortium report.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2007, Nov-15, Volume: 13, Issue:22 Pt 1

    Topics: Adolescent; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms;

2007
Phase I trial of single-dose temozolomide and continuous administration of o6-benzylguanine in children with brain tumors: a pediatric brain tumor consortium report.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2007, Nov-15, Volume: 13, Issue:22 Pt 1

    Topics: Adolescent; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms;

2007
Phase I trial of single-dose temozolomide and continuous administration of o6-benzylguanine in children with brain tumors: a pediatric brain tumor consortium report.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2007, Nov-15, Volume: 13, Issue:22 Pt 1

    Topics: Adolescent; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms;

2007
Pilot trial of the rate of response, safety, and tolerability of temozolomide and oral VP-16 in patients with recurrent or treatment-induced malignant central nervous system tumors.
    Surgical neurology, 2008, Volume: 69, Issue:1

    Topics: Administration, Oral; Adolescent; Adult; Aged; Antineoplastic Agents; Brain Neoplasms; Dacarbazine;

2008
Pilot trial of the rate of response, safety, and tolerability of temozolomide and oral VP-16 in patients with recurrent or treatment-induced malignant central nervous system tumors.
    Surgical neurology, 2008, Volume: 69, Issue:1

    Topics: Administration, Oral; Adolescent; Adult; Aged; Antineoplastic Agents; Brain Neoplasms; Dacarbazine;

2008
Pilot trial of the rate of response, safety, and tolerability of temozolomide and oral VP-16 in patients with recurrent or treatment-induced malignant central nervous system tumors.
    Surgical neurology, 2008, Volume: 69, Issue:1

    Topics: Administration, Oral; Adolescent; Adult; Aged; Antineoplastic Agents; Brain Neoplasms; Dacarbazine;

2008
Phase I study of temozolomide and irinotecan for recurrent malignant gliomas in patients receiving enzyme-inducing antiepileptic drugs: a north american brain tumor consortium study.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2007, Dec-01, Volume: 13, Issue:23

    Topics: Adult; Aged; Anticonvulsants; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Campt

2007
Phase I study of temozolomide and irinotecan for recurrent malignant gliomas in patients receiving enzyme-inducing antiepileptic drugs: a north american brain tumor consortium study.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2007, Dec-01, Volume: 13, Issue:23

    Topics: Adult; Aged; Anticonvulsants; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Campt

2007
Phase I study of temozolomide and irinotecan for recurrent malignant gliomas in patients receiving enzyme-inducing antiepileptic drugs: a north american brain tumor consortium study.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2007, Dec-01, Volume: 13, Issue:23

    Topics: Adult; Aged; Anticonvulsants; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Campt

2007
Convection-enhanced delivery of cintredekin besudotox (interleukin-13-PE38QQR) followed by radiation therapy with and without temozolomide in newly diagnosed malignant gliomas: phase 1 study of final safety results.
    Neurosurgery, 2007, Volume: 61, Issue:5

    Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms;

2007
Convection-enhanced delivery of cintredekin besudotox (interleukin-13-PE38QQR) followed by radiation therapy with and without temozolomide in newly diagnosed malignant gliomas: phase 1 study of final safety results.
    Neurosurgery, 2007, Volume: 61, Issue:5

    Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms;

2007
Convection-enhanced delivery of cintredekin besudotox (interleukin-13-PE38QQR) followed by radiation therapy with and without temozolomide in newly diagnosed malignant gliomas: phase 1 study of final safety results.
    Neurosurgery, 2007, Volume: 61, Issue:5

    Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms;

2007
Cost-effectiveness of temozolomide for the treatment of newly diagnosed glioblastoma multiforme: a report from the EORTC 26981/22981 NCI-C CE3 Intergroup Study.
    Cancer, 2008, Mar-15, Volume: 112, Issue:6

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cost-Benefit Analysis;

2008
Cost-effectiveness of temozolomide for the treatment of newly diagnosed glioblastoma multiforme: a report from the EORTC 26981/22981 NCI-C CE3 Intergroup Study.
    Cancer, 2008, Mar-15, Volume: 112, Issue:6

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cost-Benefit Analysis;

2008
Cost-effectiveness of temozolomide for the treatment of newly diagnosed glioblastoma multiforme: a report from the EORTC 26981/22981 NCI-C CE3 Intergroup Study.
    Cancer, 2008, Mar-15, Volume: 112, Issue:6

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cost-Benefit Analysis;

2008
Multi-institutional phase II study of temozolomide administered twice daily in the treatment of recurrent high-grade gliomas.
    Cancer, 2008, Mar-01, Volume: 112, Issue:5

    Topics: Administration, Oral; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine;

2008
Multi-institutional phase II study of temozolomide administered twice daily in the treatment of recurrent high-grade gliomas.
    Cancer, 2008, Mar-01, Volume: 112, Issue:5

    Topics: Administration, Oral; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine;

2008
Multi-institutional phase II study of temozolomide administered twice daily in the treatment of recurrent high-grade gliomas.
    Cancer, 2008, Mar-01, Volume: 112, Issue:5

    Topics: Administration, Oral; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine;

2008
Radiochemotherapy in patients with primary glioblastoma comparing two temozolomide dose regimens.
    International journal of radiation oncology, biology, physics, 2008, Jul-15, Volume: 71, Issue:4

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbaz

2008
Radiochemotherapy in patients with primary glioblastoma comparing two temozolomide dose regimens.
    International journal of radiation oncology, biology, physics, 2008, Jul-15, Volume: 71, Issue:4

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbaz

2008
Radiochemotherapy in patients with primary glioblastoma comparing two temozolomide dose regimens.
    International journal of radiation oncology, biology, physics, 2008, Jul-15, Volume: 71, Issue:4

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbaz

2008
Preliminary results from a phase I/II study of perillyl alcohol intranasal administration in adults with recurrent malignant gliomas.
    Surgical neurology, 2008, Volume: 70, Issue:3

    Topics: Administration, Intranasal; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Blood-Brain Ba

2008
Preliminary results from a phase I/II study of perillyl alcohol intranasal administration in adults with recurrent malignant gliomas.
    Surgical neurology, 2008, Volume: 70, Issue:3

    Topics: Administration, Intranasal; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Blood-Brain Ba

2008
Preliminary results from a phase I/II study of perillyl alcohol intranasal administration in adults with recurrent malignant gliomas.
    Surgical neurology, 2008, Volume: 70, Issue:3

    Topics: Administration, Intranasal; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Blood-Brain Ba

2008
Low-dose chemotherapy in combination with COX-2 inhibitors and PPAR-gamma agonists in recurrent high-grade gliomas - a phase II study.
    Oncology, 2007, Volume: 73, Issue:1-2

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Brain Neoplasms; Capecitabin

2007
Low-dose chemotherapy in combination with COX-2 inhibitors and PPAR-gamma agonists in recurrent high-grade gliomas - a phase II study.
    Oncology, 2007, Volume: 73, Issue:1-2

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Brain Neoplasms; Capecitabin

2007
Low-dose chemotherapy in combination with COX-2 inhibitors and PPAR-gamma agonists in recurrent high-grade gliomas - a phase II study.
    Oncology, 2007, Volume: 73, Issue:1-2

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Brain Neoplasms; Capecitabin

2007
Phase II trial of arsenic trioxide and ascorbic acid with temozolomide in patients with metastatic melanoma with or without central nervous system metastases.
    Melanoma research, 2008, Volume: 18, Issue:2

    Topics: Adult; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherap

2008
Phase II trial of arsenic trioxide and ascorbic acid with temozolomide in patients with metastatic melanoma with or without central nervous system metastases.
    Melanoma research, 2008, Volume: 18, Issue:2

    Topics: Adult; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherap

2008
Phase II trial of arsenic trioxide and ascorbic acid with temozolomide in patients with metastatic melanoma with or without central nervous system metastases.
    Melanoma research, 2008, Volume: 18, Issue:2

    Topics: Adult; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherap

2008
Phase II pilot study of bevacizumab in combination with temozolomide and regional radiation therapy for up-front treatment of patients with newly diagnosed glioblastoma multiforme: interim analysis of safety and tolerability.
    International journal of radiation oncology, biology, physics, 2008, Aug-01, Volume: 71, Issue:5

    Topics: Adult; Aged; Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Ant

2008
Phase II pilot study of bevacizumab in combination with temozolomide and regional radiation therapy for up-front treatment of patients with newly diagnosed glioblastoma multiforme: interim analysis of safety and tolerability.
    International journal of radiation oncology, biology, physics, 2008, Aug-01, Volume: 71, Issue:5

    Topics: Adult; Aged; Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Ant

2008
Phase II pilot study of bevacizumab in combination with temozolomide and regional radiation therapy for up-front treatment of patients with newly diagnosed glioblastoma multiforme: interim analysis of safety and tolerability.
    International journal of radiation oncology, biology, physics, 2008, Aug-01, Volume: 71, Issue:5

    Topics: Adult; Aged; Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Ant

2008
Safety and pharmacokinetics of dose-intensive imatinib mesylate plus temozolomide: phase 1 trial in adults with malignant glioma.
    Neuro-oncology, 2008, Volume: 10, Issue:3

    Topics: Adult; Aged; Anticonvulsants; Antineoplastic Combined Chemotherapy Protocols; Benzamides; Brain Neop

2008
Safety and pharmacokinetics of dose-intensive imatinib mesylate plus temozolomide: phase 1 trial in adults with malignant glioma.
    Neuro-oncology, 2008, Volume: 10, Issue:3

    Topics: Adult; Aged; Anticonvulsants; Antineoplastic Combined Chemotherapy Protocols; Benzamides; Brain Neop

2008
Safety and pharmacokinetics of dose-intensive imatinib mesylate plus temozolomide: phase 1 trial in adults with malignant glioma.
    Neuro-oncology, 2008, Volume: 10, Issue:3

    Topics: Adult; Aged; Anticonvulsants; Antineoplastic Combined Chemotherapy Protocols; Benzamides; Brain Neop

2008
Salvage chemotherapy with CPT-11 for recurrent temozolomide-refractory anaplastic astrocytoma.
    Cancer, 2008, May-01, Volume: 112, Issue:9

    Topics: Adolescent; Adult; Antineoplastic Agents; Astrocytoma; Brain Neoplasms; Camptothecin; Dacarbazine; F

2008
Salvage chemotherapy with CPT-11 for recurrent temozolomide-refractory anaplastic astrocytoma.
    Cancer, 2008, May-01, Volume: 112, Issue:9

    Topics: Adolescent; Adult; Antineoplastic Agents; Astrocytoma; Brain Neoplasms; Camptothecin; Dacarbazine; F

2008
Salvage chemotherapy with CPT-11 for recurrent temozolomide-refractory anaplastic astrocytoma.
    Cancer, 2008, May-01, Volume: 112, Issue:9

    Topics: Adolescent; Adult; Antineoplastic Agents; Astrocytoma; Brain Neoplasms; Camptothecin; Dacarbazine; F

2008
Phase II study of temozolomide, thalidomide, and celecoxib for newly diagnosed glioblastoma in adults.
    Neuro-oncology, 2008, Volume: 10, Issue:3

    Topics: Adult; Aged; Angiogenesis Inhibitors; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasm

2008
Phase II study of temozolomide, thalidomide, and celecoxib for newly diagnosed glioblastoma in adults.
    Neuro-oncology, 2008, Volume: 10, Issue:3

    Topics: Adult; Aged; Angiogenesis Inhibitors; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasm

2008
Phase II study of temozolomide, thalidomide, and celecoxib for newly diagnosed glioblastoma in adults.
    Neuro-oncology, 2008, Volume: 10, Issue:3

    Topics: Adult; Aged; Angiogenesis Inhibitors; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasm

2008
Temozolomide three weeks on and one week off as first line therapy for patients with recurrent or progressive low grade gliomas.
    Journal of neuro-oncology, 2008, Volume: 89, Issue:2

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chromosomes, Human, Pair 1; Dacarba

2008
Temozolomide three weeks on and one week off as first line therapy for patients with recurrent or progressive low grade gliomas.
    Journal of neuro-oncology, 2008, Volume: 89, Issue:2

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chromosomes, Human, Pair 1; Dacarba

2008
Temozolomide three weeks on and one week off as first line therapy for patients with recurrent or progressive low grade gliomas.
    Journal of neuro-oncology, 2008, Volume: 89, Issue:2

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chromosomes, Human, Pair 1; Dacarba

2008
Radiochemotherapy with temozolomide as re-irradiation using high precision fractionated stereotactic radiotherapy (FSRT) in patients with recurrent gliomas.
    Journal of neuro-oncology, 2008, Volume: 89, Issue:2

    Topics: Adolescent; Adult; Antineoplastic Agents, Alkylating; Brain Neoplasms; Child; Combined Modality Ther

2008
Radiochemotherapy with temozolomide as re-irradiation using high precision fractionated stereotactic radiotherapy (FSRT) in patients with recurrent gliomas.
    Journal of neuro-oncology, 2008, Volume: 89, Issue:2

    Topics: Adolescent; Adult; Antineoplastic Agents, Alkylating; Brain Neoplasms; Child; Combined Modality Ther

2008
Radiochemotherapy with temozolomide as re-irradiation using high precision fractionated stereotactic radiotherapy (FSRT) in patients with recurrent gliomas.
    Journal of neuro-oncology, 2008, Volume: 89, Issue:2

    Topics: Adolescent; Adult; Antineoplastic Agents, Alkylating; Brain Neoplasms; Child; Combined Modality Ther

2008
CPT-11 for recurrent temozolomide-refractory 1p19q co-deleted anaplastic oligodendroglioma.
    Journal of neuro-oncology, 2008, Volume: 89, Issue:2

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Phytogenic; Brain Neoplasms;

2008
CPT-11 for recurrent temozolomide-refractory 1p19q co-deleted anaplastic oligodendroglioma.
    Journal of neuro-oncology, 2008, Volume: 89, Issue:2

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Phytogenic; Brain Neoplasms;

2008
CPT-11 for recurrent temozolomide-refractory 1p19q co-deleted anaplastic oligodendroglioma.
    Journal of neuro-oncology, 2008, Volume: 89, Issue:2

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Phytogenic; Brain Neoplasms;

2008
A phase I trial of temozolomide and lomustine in newly diagnosed high-grade gliomas of childhood.
    Neuro-oncology, 2008, Volume: 10, Issue:4

    Topics: Adolescent; Adult; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols

2008
A phase I trial of temozolomide and lomustine in newly diagnosed high-grade gliomas of childhood.
    Neuro-oncology, 2008, Volume: 10, Issue:4

    Topics: Adolescent; Adult; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols

2008
A phase I trial of temozolomide and lomustine in newly diagnosed high-grade gliomas of childhood.
    Neuro-oncology, 2008, Volume: 10, Issue:4

    Topics: Adolescent; Adult; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols

2008
Temozolomide: a new oral cytotoxic chemotherapeutic agent with promising activity against primary brain tumours.
    European journal of cancer (Oxford, England : 1990), 1993, Volume: 29A, Issue:7

    Topics: Administration, Oral; Antineoplastic Agents; Astrocytoma; Brain; Brain Neoplasms; Dacarbazine; Dose-

1993
Temozolomide: a new oral cytotoxic chemotherapeutic agent with promising activity against primary brain tumours.
    European journal of cancer (Oxford, England : 1990), 1993, Volume: 29A, Issue:7

    Topics: Administration, Oral; Antineoplastic Agents; Astrocytoma; Brain; Brain Neoplasms; Dacarbazine; Dose-

1993
Temozolomide: a new oral cytotoxic chemotherapeutic agent with promising activity against primary brain tumours.
    European journal of cancer (Oxford, England : 1990), 1993, Volume: 29A, Issue:7

    Topics: Administration, Oral; Antineoplastic Agents; Astrocytoma; Brain; Brain Neoplasms; Dacarbazine; Dose-

1993
The Charing Cross Hospital experience with temozolomide in patients with gliomas.
    European journal of cancer (Oxford, England : 1990), 1996, Volume: 32A, Issue:13

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbaz

1996
The Charing Cross Hospital experience with temozolomide in patients with gliomas.
    European journal of cancer (Oxford, England : 1990), 1996, Volume: 32A, Issue:13

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbaz

1996
The Charing Cross Hospital experience with temozolomide in patients with gliomas.
    European journal of cancer (Oxford, England : 1990), 1996, Volume: 32A, Issue:13

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbaz

1996
Multicentre CRC phase II trial of temozolomide in recurrent or progressive high-grade glioma.
    Cancer chemotherapy and pharmacology, 1997, Volume: 40, Issue:6

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Female; Glioma; Humans

1997
Multicentre CRC phase II trial of temozolomide in recurrent or progressive high-grade glioma.
    Cancer chemotherapy and pharmacology, 1997, Volume: 40, Issue:6

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Female; Glioma; Humans

1997
Multicentre CRC phase II trial of temozolomide in recurrent or progressive high-grade glioma.
    Cancer chemotherapy and pharmacology, 1997, Volume: 40, Issue:6

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Female; Glioma; Humans

1997
Phase I trial of temozolomide using an extended continuous oral schedule.
    Cancer research, 1998, Oct-01, Volume: 58, Issue:19

    Topics: Administration, Oral; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Calibration;

1998
Phase I trial of temozolomide using an extended continuous oral schedule.
    Cancer research, 1998, Oct-01, Volume: 58, Issue:19

    Topics: Administration, Oral; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Calibration;

1998
Phase I trial of temozolomide using an extended continuous oral schedule.
    Cancer research, 1998, Oct-01, Volume: 58, Issue:19

    Topics: Administration, Oral; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Calibration;

1998
Pharmacokinetics of temozolomide in association with fotemustine in malignant melanoma and malignant glioma patients: comparison of oral, intravenous, and hepatic intra-arterial administration.
    Cancer chemotherapy and pharmacology, 1998, Volume: 42, Issue:6

    Topics: Administration, Oral; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Blood-Brain Barri

1998
Pharmacokinetics of temozolomide in association with fotemustine in malignant melanoma and malignant glioma patients: comparison of oral, intravenous, and hepatic intra-arterial administration.
    Cancer chemotherapy and pharmacology, 1998, Volume: 42, Issue:6

    Topics: Administration, Oral; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Blood-Brain Barri

1998
Pharmacokinetics of temozolomide in association with fotemustine in malignant melanoma and malignant glioma patients: comparison of oral, intravenous, and hepatic intra-arterial administration.
    Cancer chemotherapy and pharmacology, 1998, Volume: 42, Issue:6

    Topics: Administration, Oral; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Blood-Brain Barri

1998
Sequential administration of temozolomide and fotemustine: depletion of O6-alkyl guanine-DNA transferase in blood lymphocytes and in tumours.
    Annals of oncology : official journal of the European Society for Medical Oncology, 1999, Volume: 10, Issue:7

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Dacarbazine; Dose-Resp

1999
Sequential administration of temozolomide and fotemustine: depletion of O6-alkyl guanine-DNA transferase in blood lymphocytes and in tumours.
    Annals of oncology : official journal of the European Society for Medical Oncology, 1999, Volume: 10, Issue:7

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Dacarbazine; Dose-Resp

1999
Sequential administration of temozolomide and fotemustine: depletion of O6-alkyl guanine-DNA transferase in blood lymphocytes and in tumours.
    Annals of oncology : official journal of the European Society for Medical Oncology, 1999, Volume: 10, Issue:7

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Dacarbazine; Dose-Resp

1999
Multicenter phase II trial of temozolomide in patients with anaplastic astrocytoma or anaplastic oligoastrocytoma at first relapse. Temodal Brain Tumor Group.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1999, Volume: 17, Issue:9

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neoplasms; Dacarbazine; Female; H

1999
Multicenter phase II trial of temozolomide in patients with anaplastic astrocytoma or anaplastic oligoastrocytoma at first relapse. Temodal Brain Tumor Group.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1999, Volume: 17, Issue:9

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neoplasms; Dacarbazine; Female; H

1999
Multicenter phase II trial of temozolomide in patients with anaplastic astrocytoma or anaplastic oligoastrocytoma at first relapse. Temodal Brain Tumor Group.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1999, Volume: 17, Issue:9

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neoplasms; Dacarbazine; Female; H

1999
Phase I dose-escalation and pharmacokinetic study of temozolomide (SCH 52365) for refractory or relapsing malignancies.
    British journal of cancer, 1999, Volume: 81, Issue:6

    Topics: Administration, Oral; Adult; Aged; Antineoplastic Agents, Alkylating; Biological Availability; Brain

1999
Phase I dose-escalation and pharmacokinetic study of temozolomide (SCH 52365) for refractory or relapsing malignancies.
    British journal of cancer, 1999, Volume: 81, Issue:6

    Topics: Administration, Oral; Adult; Aged; Antineoplastic Agents, Alkylating; Biological Availability; Brain

1999
Phase I dose-escalation and pharmacokinetic study of temozolomide (SCH 52365) for refractory or relapsing malignancies.
    British journal of cancer, 1999, Volume: 81, Issue:6

    Topics: Administration, Oral; Adult; Aged; Antineoplastic Agents, Alkylating; Biological Availability; Brain

1999
Early evaluation of tumour metabolic response using [18F]fluorodeoxyglucose and positron emission tomography: a pilot study following the phase II chemotherapy schedule for temozolomide in recurrent high-grade gliomas.
    British journal of cancer, 2000, Volume: 82, Issue:3

    Topics: Adult; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Evaluation Studies as Topic;

2000
Early evaluation of tumour metabolic response using [18F]fluorodeoxyglucose and positron emission tomography: a pilot study following the phase II chemotherapy schedule for temozolomide in recurrent high-grade gliomas.
    British journal of cancer, 2000, Volume: 82, Issue:3

    Topics: Adult; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Evaluation Studies as Topic;

2000
Early evaluation of tumour metabolic response using [18F]fluorodeoxyglucose and positron emission tomography: a pilot study following the phase II chemotherapy schedule for temozolomide in recurrent high-grade gliomas.
    British journal of cancer, 2000, Volume: 82, Issue:3

    Topics: Adult; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Evaluation Studies as Topic;

2000
Health-related quality of life in patients treated with temozolomide versus procarbazine for recurrent glioblastoma multiforme.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2000, Volume: 18, Issue:7

    Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine;

2000
Health-related quality of life in patients treated with temozolomide versus procarbazine for recurrent glioblastoma multiforme.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2000, Volume: 18, Issue:7

    Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine;

2000
Health-related quality of life in patients treated with temozolomide versus procarbazine for recurrent glioblastoma multiforme.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2000, Volume: 18, Issue:7

    Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine;

2000
A phase II study of temozolomide vs. procarbazine in patients with glioblastoma multiforme at first relapse.
    British journal of cancer, 2000, Volume: 83, Issue:5

    Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine;

2000
A phase II study of temozolomide vs. procarbazine in patients with glioblastoma multiforme at first relapse.
    British journal of cancer, 2000, Volume: 83, Issue:5

    Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine;

2000
A phase II study of temozolomide vs. procarbazine in patients with glioblastoma multiforme at first relapse.
    British journal of cancer, 2000, Volume: 83, Issue:5

    Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine;

2000
Health-related quality of life in patients with anaplastic astrocytoma during treatment with temozolomide.
    European journal of cancer (Oxford, England : 1990), 2000, Volume: 36, Issue:14

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neoplasms; Dacarbazine; Disease P

2000
Health-related quality of life in patients with anaplastic astrocytoma during treatment with temozolomide.
    European journal of cancer (Oxford, England : 1990), 2000, Volume: 36, Issue:14

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neoplasms; Dacarbazine; Disease P

2000
Health-related quality of life in patients with anaplastic astrocytoma during treatment with temozolomide.
    European journal of cancer (Oxford, England : 1990), 2000, Volume: 36, Issue:14

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neoplasms; Dacarbazine; Disease P

2000
Phase II study of temozolomide in heavily pretreated cancer patients with brain metastases.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2001, Volume: 12, Issue:2

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Drug Evaluation; Femal

2001
Phase II study of temozolomide in heavily pretreated cancer patients with brain metastases.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2001, Volume: 12, Issue:2

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Drug Evaluation; Femal

2001
Phase II study of temozolomide in heavily pretreated cancer patients with brain metastases.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2001, Volume: 12, Issue:2

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Drug Evaluation; Femal

2001
Temozolomide as a second-line systemic regimen in recurrent high-grade glioma: a phase II study.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2001, Volume: 12, Issue:2

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Disease Progression; D

2001
Temozolomide as a second-line systemic regimen in recurrent high-grade glioma: a phase II study.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2001, Volume: 12, Issue:2

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Disease Progression; D

2001
Temozolomide as a second-line systemic regimen in recurrent high-grade glioma: a phase II study.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2001, Volume: 12, Issue:2

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Disease Progression; D

2001
Multicenter phase II trial of temozolomide in patients with glioblastoma multiforme at first relapse.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2001, Volume: 12, Issue:2

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Disease-Free Survival;

2001
Multicenter phase II trial of temozolomide in patients with glioblastoma multiforme at first relapse.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2001, Volume: 12, Issue:2

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Disease-Free Survival;

2001
Multicenter phase II trial of temozolomide in patients with glioblastoma multiforme at first relapse.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2001, Volume: 12, Issue:2

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Disease-Free Survival;

2001
A phase I trial of 1,3-bis(2-chloroethyl)-1-nitrosourea plus temozolomide: a North American Brain Tumor Consortium study.
    Neuro-oncology, 2000, Volume: 2, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Carmustine; Dacarbazine; Dose-Response Relations

2000
A phase I trial of 1,3-bis(2-chloroethyl)-1-nitrosourea plus temozolomide: a North American Brain Tumor Consortium study.
    Neuro-oncology, 2000, Volume: 2, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Carmustine; Dacarbazine; Dose-Response Relations

2000
A phase I trial of 1,3-bis(2-chloroethyl)-1-nitrosourea plus temozolomide: a North American Brain Tumor Consortium study.
    Neuro-oncology, 2000, Volume: 2, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Carmustine; Dacarbazine; Dose-Response Relations

2000
Safety and efficacy of temozolomide in patients with recurrent anaplastic oligodendrogliomas after standard radiotherapy and chemotherapy.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2001, May-01, Volume: 19, Issue:9

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neoplasms; Dacarbazine; Humans; M

2001
Safety and efficacy of temozolomide in patients with recurrent anaplastic oligodendrogliomas after standard radiotherapy and chemotherapy.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2001, May-01, Volume: 19, Issue:9

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neoplasms; Dacarbazine; Humans; M

2001
Safety and efficacy of temozolomide in patients with recurrent anaplastic oligodendrogliomas after standard radiotherapy and chemotherapy.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2001, May-01, Volume: 19, Issue:9

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neoplasms; Dacarbazine; Humans; M

2001
A phase II trial of temozolomide for patients with recurrent or progressive brain metastases.
    Journal of neuro-oncology, 2001, Volume: 53, Issue:3

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Carcinoma, Non-Small-Cell Lung; Dac

2001
A phase II trial of temozolomide for patients with recurrent or progressive brain metastases.
    Journal of neuro-oncology, 2001, Volume: 53, Issue:3

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Carcinoma, Non-Small-Cell Lung; Dac

2001
A phase II trial of temozolomide for patients with recurrent or progressive brain metastases.
    Journal of neuro-oncology, 2001, Volume: 53, Issue:3

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Carcinoma, Non-Small-Cell Lung; Dac

2001
A phase II study of extended low-dose temozolomide in recurrent malignant gliomas.
    Neuro-oncology, 2002, Volume: 4, Issue:1

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Dose-Response Relation

2002
A phase II study of extended low-dose temozolomide in recurrent malignant gliomas.
    Neuro-oncology, 2002, Volume: 4, Issue:1

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Dose-Response Relation

2002
A phase II study of extended low-dose temozolomide in recurrent malignant gliomas.
    Neuro-oncology, 2002, Volume: 4, Issue:1

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Dose-Response Relation

2002
Temozolomide in combination with docetaxel in patients with advanced melanoma: a phase II study of the Hellenic Cooperative Oncology Group.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2002, Jan-15, Volume: 20, Issue:2

    Topics: Administration, Oral; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms;

2002
Temozolomide in combination with docetaxel in patients with advanced melanoma: a phase II study of the Hellenic Cooperative Oncology Group.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2002, Jan-15, Volume: 20, Issue:2

    Topics: Administration, Oral; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms;

2002
Temozolomide in combination with docetaxel in patients with advanced melanoma: a phase II study of the Hellenic Cooperative Oncology Group.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2002, Jan-15, Volume: 20, Issue:2

    Topics: Administration, Oral; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms;

2002
Promising survival for patients with newly diagnosed glioblastoma multiforme treated with concomitant radiation plus temozolomide followed by adjuvant temozolomide.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2002, Mar-01, Volume: 20, Issue:5

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant; Combined Mo

2002
Promising survival for patients with newly diagnosed glioblastoma multiforme treated with concomitant radiation plus temozolomide followed by adjuvant temozolomide.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2002, Mar-01, Volume: 20, Issue:5

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant; Combined Mo

2002
Promising survival for patients with newly diagnosed glioblastoma multiforme treated with concomitant radiation plus temozolomide followed by adjuvant temozolomide.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2002, Mar-01, Volume: 20, Issue:5

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant; Combined Mo

2002
Phase II trial of temozolomide plus the matrix metalloproteinase inhibitor, marimastat, in recurrent and progressive glioblastoma multiforme.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2002, Mar-01, Volume: 20, Issue:5

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Brai

2002
Phase II trial of temozolomide plus the matrix metalloproteinase inhibitor, marimastat, in recurrent and progressive glioblastoma multiforme.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2002, Mar-01, Volume: 20, Issue:5

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Brai

2002
Phase II trial of temozolomide plus the matrix metalloproteinase inhibitor, marimastat, in recurrent and progressive glioblastoma multiforme.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2002, Mar-01, Volume: 20, Issue:5

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Brai

2002
Effect of temozolomide on central nervous system relapse in patients with advanced melanoma.
    Melanoma research, 2002, Volume: 12, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Case-Control Stu

2002
Effect of temozolomide on central nervous system relapse in patients with advanced melanoma.
    Melanoma research, 2002, Volume: 12, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Case-Control Stu

2002
Effect of temozolomide on central nervous system relapse in patients with advanced melanoma.
    Melanoma research, 2002, Volume: 12, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Case-Control Stu

2002
Temozolomide and whole brain irradiation in melanoma metastatic to the brain: a phase II trial of the Cytokine Working Group.
    Journal of cancer research and clinical oncology, 2002, Volume: 128, Issue:4

    Topics: Administration, Oral; Adult; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality T

2002
Temozolomide and whole brain irradiation in melanoma metastatic to the brain: a phase II trial of the Cytokine Working Group.
    Journal of cancer research and clinical oncology, 2002, Volume: 128, Issue:4

    Topics: Administration, Oral; Adult; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality T

2002
Temozolomide and whole brain irradiation in melanoma metastatic to the brain: a phase II trial of the Cytokine Working Group.
    Journal of cancer research and clinical oncology, 2002, Volume: 128, Issue:4

    Topics: Administration, Oral; Adult; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality T

2002
Concomitant radiotherapy and metronomic temozolomide in pediatric high-risk brain tumors.
    Neoplasma, 2002, Volume: 49, Issue:2

    Topics: Adolescent; Antineoplastic Agents, Alkylating; Bone Marrow; Brain Neoplasms; Child; Combined Modalit

2002
Concomitant radiotherapy and metronomic temozolomide in pediatric high-risk brain tumors.
    Neoplasma, 2002, Volume: 49, Issue:2

    Topics: Adolescent; Antineoplastic Agents, Alkylating; Bone Marrow; Brain Neoplasms; Child; Combined Modalit

2002
Concomitant radiotherapy and metronomic temozolomide in pediatric high-risk brain tumors.
    Neoplasma, 2002, Volume: 49, Issue:2

    Topics: Adolescent; Antineoplastic Agents, Alkylating; Bone Marrow; Brain Neoplasms; Child; Combined Modalit

2002

Other Studies

2387 other studies available for temozolomide and Brain Neoplasms

ArticleYear
Oxaphosphinanes: new therapeutic perspectives for glioblastoma.
    Journal of medicinal chemistry, 2012, Mar-08, Volume: 55, Issue:5

    Topics: Animals; Antineoplastic Agents; Astrocytes; Brain Neoplasms; Cell Count; Cell Line, Tumor; Cell Surv

2012
Oxaphosphinanes: new therapeutic perspectives for glioblastoma.
    Journal of medicinal chemistry, 2012, Mar-08, Volume: 55, Issue:5

    Topics: Animals; Antineoplastic Agents; Astrocytes; Brain Neoplasms; Cell Count; Cell Line, Tumor; Cell Surv

2012
Oxaphosphinanes: new therapeutic perspectives for glioblastoma.
    Journal of medicinal chemistry, 2012, Mar-08, Volume: 55, Issue:5

    Topics: Animals; Antineoplastic Agents; Astrocytes; Brain Neoplasms; Cell Count; Cell Line, Tumor; Cell Surv

2012
Inhibition of cancer-associated mutant isocitrate dehydrogenases: synthesis, structure-activity relationship, and selective antitumor activity.
    Journal of medicinal chemistry, 2014, Oct-23, Volume: 57, Issue:20

    Topics: Animals; Antineoplastic Agents; Blood-Brain Barrier; Brain Neoplasms; Crystallography, X-Ray; Drug S

2014
Inhibition of cancer-associated mutant isocitrate dehydrogenases: synthesis, structure-activity relationship, and selective antitumor activity.
    Journal of medicinal chemistry, 2014, Oct-23, Volume: 57, Issue:20

    Topics: Animals; Antineoplastic Agents; Blood-Brain Barrier; Brain Neoplasms; Crystallography, X-Ray; Drug S

2014
Inhibition of cancer-associated mutant isocitrate dehydrogenases: synthesis, structure-activity relationship, and selective antitumor activity.
    Journal of medicinal chemistry, 2014, Oct-23, Volume: 57, Issue:20

    Topics: Animals; Antineoplastic Agents; Blood-Brain Barrier; Brain Neoplasms; Crystallography, X-Ray; Drug S

2014
Design of Novel Inhibitors of Human Thymidine Phosphorylase: Synthesis, Enzyme Inhibition, in Vitro Toxicity, and Impact on Human Glioblastoma Cancer.
    Journal of medicinal chemistry, 2019, 02-14, Volume: 62, Issue:3

    Topics: Animals; Area Under Curve; Brain Neoplasms; Cell Line; Cell Line, Tumor; Drug Design; Enzyme Inhibit

2019
Design of Novel Inhibitors of Human Thymidine Phosphorylase: Synthesis, Enzyme Inhibition, in Vitro Toxicity, and Impact on Human Glioblastoma Cancer.
    Journal of medicinal chemistry, 2019, 02-14, Volume: 62, Issue:3

    Topics: Animals; Area Under Curve; Brain Neoplasms; Cell Line; Cell Line, Tumor; Drug Design; Enzyme Inhibit

2019
Design of Novel Inhibitors of Human Thymidine Phosphorylase: Synthesis, Enzyme Inhibition, in Vitro Toxicity, and Impact on Human Glioblastoma Cancer.
    Journal of medicinal chemistry, 2019, 02-14, Volume: 62, Issue:3

    Topics: Animals; Area Under Curve; Brain Neoplasms; Cell Line; Cell Line, Tumor; Drug Design; Enzyme Inhibit

2019
Carbonic Anhydrase XII Inhibitors Overcome Temozolomide Resistance in Glioblastoma.
    Journal of medicinal chemistry, 2019, 04-25, Volume: 62, Issue:8

    Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases;

2019
Carbonic Anhydrase XII Inhibitors Overcome Temozolomide Resistance in Glioblastoma.
    Journal of medicinal chemistry, 2019, 04-25, Volume: 62, Issue:8

    Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases;

2019
Carbonic Anhydrase XII Inhibitors Overcome Temozolomide Resistance in Glioblastoma.
    Journal of medicinal chemistry, 2019, 04-25, Volume: 62, Issue:8

    Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases;

2019
Targeting gliomas with triazene-based hybrids: Structure-activity relationship, mechanistic study and stability.
    European journal of medicinal chemistry, 2019, Jun-15, Volume: 172

    Topics: Antineoplastic Agents; Brain Neoplasms; Cell Movement; Cell Proliferation; Cell Survival; Dose-Respo

2019
Targeting gliomas with triazene-based hybrids: Structure-activity relationship, mechanistic study and stability.
    European journal of medicinal chemistry, 2019, Jun-15, Volume: 172

    Topics: Antineoplastic Agents; Brain Neoplasms; Cell Movement; Cell Proliferation; Cell Survival; Dose-Respo

2019
Targeting gliomas with triazene-based hybrids: Structure-activity relationship, mechanistic study and stability.
    European journal of medicinal chemistry, 2019, Jun-15, Volume: 172

    Topics: Antineoplastic Agents; Brain Neoplasms; Cell Movement; Cell Proliferation; Cell Survival; Dose-Respo

2019
The synthesis of a novel Crizotinib heptamethine cyanine dye conjugate that potentiates the cytostatic and cytotoxic effects of Crizotinib in patient-derived glioblastoma cell lines.
    Bioorganic & medicinal chemistry letters, 2019, 09-15, Volume: 29, Issue:18

    Topics: Antineoplastic Agents; Brain Neoplasms; Carbocyanines; Cell Line, Tumor; Cell Proliferation; Cell Su

2019
The synthesis of a novel Crizotinib heptamethine cyanine dye conjugate that potentiates the cytostatic and cytotoxic effects of Crizotinib in patient-derived glioblastoma cell lines.
    Bioorganic & medicinal chemistry letters, 2019, 09-15, Volume: 29, Issue:18

    Topics: Antineoplastic Agents; Brain Neoplasms; Carbocyanines; Cell Line, Tumor; Cell Proliferation; Cell Su

2019
The synthesis of a novel Crizotinib heptamethine cyanine dye conjugate that potentiates the cytostatic and cytotoxic effects of Crizotinib in patient-derived glioblastoma cell lines.
    Bioorganic & medicinal chemistry letters, 2019, 09-15, Volume: 29, Issue:18

    Topics: Antineoplastic Agents; Brain Neoplasms; Carbocyanines; Cell Line, Tumor; Cell Proliferation; Cell Su

2019
PARP inhibitor cyanine dye conjugate with enhanced cytotoxic and antiproliferative activity in patient derived glioblastoma cell lines.
    Bioorganic & medicinal chemistry letters, 2020, 07-15, Volume: 30, Issue:14

    Topics: Antineoplastic Agents; Brain Neoplasms; Carbocyanines; Cell Line, Tumor; Cell Proliferation; Cell Su

2020
PARP inhibitor cyanine dye conjugate with enhanced cytotoxic and antiproliferative activity in patient derived glioblastoma cell lines.
    Bioorganic & medicinal chemistry letters, 2020, 07-15, Volume: 30, Issue:14

    Topics: Antineoplastic Agents; Brain Neoplasms; Carbocyanines; Cell Line, Tumor; Cell Proliferation; Cell Su

2020
PARP inhibitor cyanine dye conjugate with enhanced cytotoxic and antiproliferative activity in patient derived glioblastoma cell lines.
    Bioorganic & medicinal chemistry letters, 2020, 07-15, Volume: 30, Issue:14

    Topics: Antineoplastic Agents; Brain Neoplasms; Carbocyanines; Cell Line, Tumor; Cell Proliferation; Cell Su

2020
Structures/cytotoxicity/selectivity relationship of natural steroidal saponins against GSCs and primary mechanism of tribulosaponin A.
    European journal of medicinal chemistry, 2021, Jan-15, Volume: 210

    Topics: Antineoplastic Agents; Apoptosis; Biological Products; Brain Neoplasms; Cell Proliferation; Cell Sur

2021
Structures/cytotoxicity/selectivity relationship of natural steroidal saponins against GSCs and primary mechanism of tribulosaponin A.
    European journal of medicinal chemistry, 2021, Jan-15, Volume: 210

    Topics: Antineoplastic Agents; Apoptosis; Biological Products; Brain Neoplasms; Cell Proliferation; Cell Sur

2021
Structures/cytotoxicity/selectivity relationship of natural steroidal saponins against GSCs and primary mechanism of tribulosaponin A.
    European journal of medicinal chemistry, 2021, Jan-15, Volume: 210

    Topics: Antineoplastic Agents; Apoptosis; Biological Products; Brain Neoplasms; Cell Proliferation; Cell Sur

2021
The 3-D conformational shape of N-naphthyl-cyclopenta[d]pyrimidines affects their potency as microtubule targeting agents and their antitumor activity.
    Bioorganic & medicinal chemistry, 2021, 01-01, Volume: 29

    Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Cell Proliferation; Cyclopentanes; Dose-Response Re

2021
The 3-D conformational shape of N-naphthyl-cyclopenta[d]pyrimidines affects their potency as microtubule targeting agents and their antitumor activity.
    Bioorganic & medicinal chemistry, 2021, 01-01, Volume: 29

    Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Cell Proliferation; Cyclopentanes; Dose-Response Re

2021
The 3-D conformational shape of N-naphthyl-cyclopenta[d]pyrimidines affects their potency as microtubule targeting agents and their antitumor activity.
    Bioorganic & medicinal chemistry, 2021, 01-01, Volume: 29

    Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Cell Proliferation; Cyclopentanes; Dose-Response Re

2021
Synthesis and Preclinical Validation of Novel Indole Derivatives as a GPR17 Agonist for Glioblastoma Treatment.
    Journal of medicinal chemistry, 2021, 08-12, Volume: 64, Issue:15

    Topics: Antineoplastic Agents; Brain Neoplasms; Cell Proliferation; Cell Survival; Dose-Response Relationshi

2021
Synthesis and Preclinical Validation of Novel Indole Derivatives as a GPR17 Agonist for Glioblastoma Treatment.
    Journal of medicinal chemistry, 2021, 08-12, Volume: 64, Issue:15

    Topics: Antineoplastic Agents; Brain Neoplasms; Cell Proliferation; Cell Survival; Dose-Response Relationshi

2021
Synthesis and Preclinical Validation of Novel Indole Derivatives as a GPR17 Agonist for Glioblastoma Treatment.
    Journal of medicinal chemistry, 2021, 08-12, Volume: 64, Issue:15

    Topics: Antineoplastic Agents; Brain Neoplasms; Cell Proliferation; Cell Survival; Dose-Response Relationshi

2021
Non-alkylator anti-glioblastoma agents induced cell cycle G2/M arrest and apoptosis: Design, in silico physicochemical and SAR studies of 2-aminoquinoline-3-carboxamides.
    Bioorganic & medicinal chemistry letters, 2021, 11-01, Volume: 51

    Topics: Aminoquinolines; Antineoplastic Agents; Apoptosis; Brain Neoplasms; Cell Cycle Checkpoints; Cell Lin

2021
Non-alkylator anti-glioblastoma agents induced cell cycle G2/M arrest and apoptosis: Design, in silico physicochemical and SAR studies of 2-aminoquinoline-3-carboxamides.
    Bioorganic & medicinal chemistry letters, 2021, 11-01, Volume: 51

    Topics: Aminoquinolines; Antineoplastic Agents; Apoptosis; Brain Neoplasms; Cell Cycle Checkpoints; Cell Lin

2021
Non-alkylator anti-glioblastoma agents induced cell cycle G2/M arrest and apoptosis: Design, in silico physicochemical and SAR studies of 2-aminoquinoline-3-carboxamides.
    Bioorganic & medicinal chemistry letters, 2021, 11-01, Volume: 51

    Topics: Aminoquinolines; Antineoplastic Agents; Apoptosis; Brain Neoplasms; Cell Cycle Checkpoints; Cell Lin

2021
Cyclotides Chemosensitize Glioblastoma Cells to Temozolomide.
    Journal of natural products, 2022, 01-28, Volume: 85, Issue:1

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Cell Survival; Cyclot

2022
Cyclotides Chemosensitize Glioblastoma Cells to Temozolomide.
    Journal of natural products, 2022, 01-28, Volume: 85, Issue:1

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Cell Survival; Cyclot

2022
Cyclotides Chemosensitize Glioblastoma Cells to Temozolomide.
    Journal of natural products, 2022, 01-28, Volume: 85, Issue:1

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Cell Survival; Cyclot

2022
AEG-1 silencing attenuates M2-polarization of glioma-associated microglia/macrophages and sensitizes glioma cells to temozolomide.
    Scientific reports, 2021, 08-30, Volume: 11, Issue:1

    Topics: Astrocytes; Brain Neoplasms; Cell Survival; Computational Biology; Cytokines; DNA Damage; Gene Expre

2021
AEG-1 silencing attenuates M2-polarization of glioma-associated microglia/macrophages and sensitizes glioma cells to temozolomide.
    Scientific reports, 2021, 08-30, Volume: 11, Issue:1

    Topics: Astrocytes; Brain Neoplasms; Cell Survival; Computational Biology; Cytokines; DNA Damage; Gene Expre

2021
AEG-1 silencing attenuates M2-polarization of glioma-associated microglia/macrophages and sensitizes glioma cells to temozolomide.
    Scientific reports, 2021, 08-30, Volume: 11, Issue:1

    Topics: Astrocytes; Brain Neoplasms; Cell Survival; Computational Biology; Cytokines; DNA Damage; Gene Expre

2021
Temozolomide is additive with cytotoxic effect of irradiation in canine glioma cell lines.
    Veterinary medicine and science, 2021, Volume: 7, Issue:6

    Topics: Animals; Brain Neoplasms; Cell Line; Dacarbazine; DNA Modification Methylases; DNA Repair Enzymes; D

2021
Temozolomide is additive with cytotoxic effect of irradiation in canine glioma cell lines.
    Veterinary medicine and science, 2021, Volume: 7, Issue:6

    Topics: Animals; Brain Neoplasms; Cell Line; Dacarbazine; DNA Modification Methylases; DNA Repair Enzymes; D

2021
Temozolomide is additive with cytotoxic effect of irradiation in canine glioma cell lines.
    Veterinary medicine and science, 2021, Volume: 7, Issue:6

    Topics: Animals; Brain Neoplasms; Cell Line; Dacarbazine; DNA Modification Methylases; DNA Repair Enzymes; D

2021
An international perspective on the management of glioblastoma.
    Chinese clinical oncology, 2021, Volume: 10, Issue:4

    Topics: Brain Neoplasms; Glioblastoma; Humans; Internationality; Temozolomide

2021
An international perspective on the management of glioblastoma.
    Chinese clinical oncology, 2021, Volume: 10, Issue:4

    Topics: Brain Neoplasms; Glioblastoma; Humans; Internationality; Temozolomide

2021
An international perspective on the management of glioblastoma.
    Chinese clinical oncology, 2021, Volume: 10, Issue:4

    Topics: Brain Neoplasms; Glioblastoma; Humans; Internationality; Temozolomide

2021
Radiotherapy intensification for glioblastoma: enhancing the backbone of treatment.
    Chinese clinical oncology, 2021, Volume: 10, Issue:4

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Glioblastoma; Humans; Radiotherapy, Intensity-Mo

2021
Radiotherapy intensification for glioblastoma: enhancing the backbone of treatment.
    Chinese clinical oncology, 2021, Volume: 10, Issue:4

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Glioblastoma; Humans; Radiotherapy, Intensity-Mo

2021
Radiotherapy intensification for glioblastoma: enhancing the backbone of treatment.
    Chinese clinical oncology, 2021, Volume: 10, Issue:4

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Glioblastoma; Humans; Radiotherapy, Intensity-Mo

2021
Lomustine and nimustine exert efficient antitumor effects against glioblastoma models with acquired temozolomide resistance.
    Cancer science, 2021, Volume: 112, Issue:11

    Topics: Animals; Antineoplastic Agents; Brain Neoplasms; DNA Modification Methylases; DNA Repair Enzymes; Dr

2021
Lomustine and nimustine exert efficient antitumor effects against glioblastoma models with acquired temozolomide resistance.
    Cancer science, 2021, Volume: 112, Issue:11

    Topics: Animals; Antineoplastic Agents; Brain Neoplasms; DNA Modification Methylases; DNA Repair Enzymes; Dr

2021
Lomustine and nimustine exert efficient antitumor effects against glioblastoma models with acquired temozolomide resistance.
    Cancer science, 2021, Volume: 112, Issue:11

    Topics: Animals; Antineoplastic Agents; Brain Neoplasms; DNA Modification Methylases; DNA Repair Enzymes; Dr

2021
Targeted therapy with anlotinib for a leptomeningeal spread recurrent glioblastoma patient.
    Progress in brain research, 2021, Volume: 265

    Topics: Adult; Brain Neoplasms; Glioblastoma; Humans; Indoles; Quinolines; Temozolomide

2021
Targeted therapy with anlotinib for a leptomeningeal spread recurrent glioblastoma patient.
    Progress in brain research, 2021, Volume: 265

    Topics: Adult; Brain Neoplasms; Glioblastoma; Humans; Indoles; Quinolines; Temozolomide

2021
Targeted therapy with anlotinib for a leptomeningeal spread recurrent glioblastoma patient.
    Progress in brain research, 2021, Volume: 265

    Topics: Adult; Brain Neoplasms; Glioblastoma; Humans; Indoles; Quinolines; Temozolomide

2021
Interplay of m
    Clinical and translational medicine, 2021, Volume: 11, Issue:9

    Topics: Adenosine; Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Drug Resis

2021
Interplay of m
    Clinical and translational medicine, 2021, Volume: 11, Issue:9

    Topics: Adenosine; Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Drug Resis

2021
Interplay of m
    Clinical and translational medicine, 2021, Volume: 11, Issue:9

    Topics: Adenosine; Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Drug Resis

2021
Functional drug susceptibility testing using single-cell mass predicts treatment outcome in patient-derived cancer neurosphere models.
    Cell reports, 2021, 10-05, Volume: 37, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Biomarkers, Tumor; Brain Neoplasms; Cell Size; DNA Methylation; D

2021
Functional drug susceptibility testing using single-cell mass predicts treatment outcome in patient-derived cancer neurosphere models.
    Cell reports, 2021, 10-05, Volume: 37, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Biomarkers, Tumor; Brain Neoplasms; Cell Size; DNA Methylation; D

2021
Functional drug susceptibility testing using single-cell mass predicts treatment outcome in patient-derived cancer neurosphere models.
    Cell reports, 2021, 10-05, Volume: 37, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Biomarkers, Tumor; Brain Neoplasms; Cell Size; DNA Methylation; D

2021
Silk Microneedle Patch Capable of On-Demand Multidrug Delivery to the Brain for Glioblastoma Treatment.
    Advanced materials (Deerfield Beach, Fla.), 2022, Volume: 34, Issue:1

    Topics: Animals; Brain; Brain Neoplasms; Cell Line, Tumor; Drug Delivery Systems; Glioblastoma; Humans; Mice

2022
Silk Microneedle Patch Capable of On-Demand Multidrug Delivery to the Brain for Glioblastoma Treatment.
    Advanced materials (Deerfield Beach, Fla.), 2022, Volume: 34, Issue:1

    Topics: Animals; Brain; Brain Neoplasms; Cell Line, Tumor; Drug Delivery Systems; Glioblastoma; Humans; Mice

2022
Silk Microneedle Patch Capable of On-Demand Multidrug Delivery to the Brain for Glioblastoma Treatment.
    Advanced materials (Deerfield Beach, Fla.), 2022, Volume: 34, Issue:1

    Topics: Animals; Brain; Brain Neoplasms; Cell Line, Tumor; Drug Delivery Systems; Glioblastoma; Humans; Mice

2022
Pharmacological inhibition of serine synthesis enhances temozolomide efficacy by decreasing O
    Laboratory investigation; a journal of technical methods and pathology, 2022, Volume: 102, Issue:2

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Cell Survival; DNA Da

2022
Pharmacological inhibition of serine synthesis enhances temozolomide efficacy by decreasing O
    Laboratory investigation; a journal of technical methods and pathology, 2022, Volume: 102, Issue:2

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Cell Survival; DNA Da

2022
Pharmacological inhibition of serine synthesis enhances temozolomide efficacy by decreasing O
    Laboratory investigation; a journal of technical methods and pathology, 2022, Volume: 102, Issue:2

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Cell Survival; DNA Da

2022
The E3 Ubiquitin Ligase NEDD4-1 Mediates Temozolomide-Resistant Glioblastoma through PTEN Attenuation and Redox Imbalance in Nrf2-HO-1 Axis.
    International journal of molecular sciences, 2021, Sep-23, Volume: 22, Issue:19

    Topics: Aged; Animals; Brain Neoplasms; Cell Line, Tumor; Down-Regulation; Drug Resistance, Neoplasm; Female

2021
The E3 Ubiquitin Ligase NEDD4-1 Mediates Temozolomide-Resistant Glioblastoma through PTEN Attenuation and Redox Imbalance in Nrf2-HO-1 Axis.
    International journal of molecular sciences, 2021, Sep-23, Volume: 22, Issue:19

    Topics: Aged; Animals; Brain Neoplasms; Cell Line, Tumor; Down-Regulation; Drug Resistance, Neoplasm; Female

2021
The E3 Ubiquitin Ligase NEDD4-1 Mediates Temozolomide-Resistant Glioblastoma through PTEN Attenuation and Redox Imbalance in Nrf2-HO-1 Axis.
    International journal of molecular sciences, 2021, Sep-23, Volume: 22, Issue:19

    Topics: Aged; Animals; Brain Neoplasms; Cell Line, Tumor; Down-Regulation; Drug Resistance, Neoplasm; Female

2021
Preclinical Evaluation of Sodium Selenite in Mice: Toxicological and Tumor Regression Studies after Striatum Implantation of Human Glioblastoma Stem Cells.
    International journal of molecular sciences, 2021, Sep-30, Volume: 22, Issue:19

    Topics: Animals; Apoptosis; Brain Neoplasms; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Proliferation; C

2021
Preclinical Evaluation of Sodium Selenite in Mice: Toxicological and Tumor Regression Studies after Striatum Implantation of Human Glioblastoma Stem Cells.
    International journal of molecular sciences, 2021, Sep-30, Volume: 22, Issue:19

    Topics: Animals; Apoptosis; Brain Neoplasms; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Proliferation; C

2021
Preclinical Evaluation of Sodium Selenite in Mice: Toxicological and Tumor Regression Studies after Striatum Implantation of Human Glioblastoma Stem Cells.
    International journal of molecular sciences, 2021, Sep-30, Volume: 22, Issue:19

    Topics: Animals; Apoptosis; Brain Neoplasms; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Proliferation; C

2021
Viability fingerprint of glioblastoma cell lines: roles of mitotic, proliferative, and epigenetic targets.
    Scientific reports, 2021, 10-13, Volume: 11, Issue:1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Brain Neoplasms; Cell Cycle; Cell Line,

2021
Viability fingerprint of glioblastoma cell lines: roles of mitotic, proliferative, and epigenetic targets.
    Scientific reports, 2021, 10-13, Volume: 11, Issue:1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Brain Neoplasms; Cell Cycle; Cell Line,

2021
Viability fingerprint of glioblastoma cell lines: roles of mitotic, proliferative, and epigenetic targets.
    Scientific reports, 2021, 10-13, Volume: 11, Issue:1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Brain Neoplasms; Cell Cycle; Cell Line,

2021
Accurately Controlled Delivery of Temozolomide by Biocompatible UiO-66-NH
    International journal of nanomedicine, 2021, Volume: 16

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Glioblastoma; Glioma; Humans;

2021
Accurately Controlled Delivery of Temozolomide by Biocompatible UiO-66-NH
    International journal of nanomedicine, 2021, Volume: 16

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Glioblastoma; Glioma; Humans;

2021
Accurately Controlled Delivery of Temozolomide by Biocompatible UiO-66-NH
    International journal of nanomedicine, 2021, Volume: 16

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Glioblastoma; Glioma; Humans;

2021
Cytotoxicity Effect of Quinoin, Type 1 Ribosome-Inactivating Protein from Quinoa Seeds, on Glioblastoma Cells.
    Toxins, 2021, 09-25, Volume: 13, Issue:10

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Chenopodiu

2021
Cytotoxicity Effect of Quinoin, Type 1 Ribosome-Inactivating Protein from Quinoa Seeds, on Glioblastoma Cells.
    Toxins, 2021, 09-25, Volume: 13, Issue:10

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Chenopodiu

2021
Cytotoxicity Effect of Quinoin, Type 1 Ribosome-Inactivating Protein from Quinoa Seeds, on Glioblastoma Cells.
    Toxins, 2021, 09-25, Volume: 13, Issue:10

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Chenopodiu

2021
Tumor-Associated Microglia/Macrophages as a Predictor for Survival in Glioblastoma and Temozolomide-Induced Changes in CXCR2 Signaling with New Resistance Overcoming Strategy by Combination Therapy.
    International journal of molecular sciences, 2021, Oct-16, Volume: 22, Issue:20

    Topics: Adult; Aged; Aged, 80 and over; Animals; Antineoplastic Agents, Alkylating; Antineoplastic Combined

2021
Tumor-Associated Microglia/Macrophages as a Predictor for Survival in Glioblastoma and Temozolomide-Induced Changes in CXCR2 Signaling with New Resistance Overcoming Strategy by Combination Therapy.
    International journal of molecular sciences, 2021, Oct-16, Volume: 22, Issue:20

    Topics: Adult; Aged; Aged, 80 and over; Animals; Antineoplastic Agents, Alkylating; Antineoplastic Combined

2021
Tumor-Associated Microglia/Macrophages as a Predictor for Survival in Glioblastoma and Temozolomide-Induced Changes in CXCR2 Signaling with New Resistance Overcoming Strategy by Combination Therapy.
    International journal of molecular sciences, 2021, Oct-16, Volume: 22, Issue:20

    Topics: Adult; Aged; Aged, 80 and over; Animals; Antineoplastic Agents, Alkylating; Antineoplastic Combined

2021
A combined treatment regimen of MGMT-modified γδ T cells and temozolomide chemotherapy is effective against primary high grade gliomas.
    Scientific reports, 2021, 10-26, Volume: 11, Issue:1

    Topics: Animals; Brain Neoplasms; Glioma; Humans; Immunotherapy; Mice, Nude; O(6)-Methylguanine-DNA Methyltr

2021
A combined treatment regimen of MGMT-modified γδ T cells and temozolomide chemotherapy is effective against primary high grade gliomas.
    Scientific reports, 2021, 10-26, Volume: 11, Issue:1

    Topics: Animals; Brain Neoplasms; Glioma; Humans; Immunotherapy; Mice, Nude; O(6)-Methylguanine-DNA Methyltr

2021
A combined treatment regimen of MGMT-modified γδ T cells and temozolomide chemotherapy is effective against primary high grade gliomas.
    Scientific reports, 2021, 10-26, Volume: 11, Issue:1

    Topics: Animals; Brain Neoplasms; Glioma; Humans; Immunotherapy; Mice, Nude; O(6)-Methylguanine-DNA Methyltr

2021
Related expression of TRKA and P75 receptors and the changing copy number of
    Drug metabolism and personalized therapy, 2020, 09-04, Volume: 35, Issue:4

    Topics: Brain Neoplasms; Cisplatin; DNA Copy Number Variations; Humans; In Situ Hybridization, Fluorescence;

2020
Related expression of TRKA and P75 receptors and the changing copy number of
    Drug metabolism and personalized therapy, 2020, 09-04, Volume: 35, Issue:4

    Topics: Brain Neoplasms; Cisplatin; DNA Copy Number Variations; Humans; In Situ Hybridization, Fluorescence;

2020
Related expression of TRKA and P75 receptors and the changing copy number of
    Drug metabolism and personalized therapy, 2020, 09-04, Volume: 35, Issue:4

    Topics: Brain Neoplasms; Cisplatin; DNA Copy Number Variations; Humans; In Situ Hybridization, Fluorescence;

2020
NSUN6, an RNA methyltransferase of 5-mC controls glioblastoma response to temozolomide (TMZ) via NELFB and RPS6KB2 interaction.
    Cancer biology & therapy, 2021, 12-02, Volume: 22, Issue:10-12

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; DNA Modification Methylases; D

2021
NSUN6, an RNA methyltransferase of 5-mC controls glioblastoma response to temozolomide (TMZ) via NELFB and RPS6KB2 interaction.
    Cancer biology & therapy, 2021, 12-02, Volume: 22, Issue:10-12

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; DNA Modification Methylases; D

2021
NSUN6, an RNA methyltransferase of 5-mC controls glioblastoma response to temozolomide (TMZ) via NELFB and RPS6KB2 interaction.
    Cancer biology & therapy, 2021, 12-02, Volume: 22, Issue:10-12

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; DNA Modification Methylases; D

2021
Circumventing Drug Resistance Pathways with a Nanoparticle-Based Photodynamic Method.
    Nano letters, 2021, 11-10, Volume: 21, Issue:21

    Topics: Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Drug Resistance, Ne

2021
Circumventing Drug Resistance Pathways with a Nanoparticle-Based Photodynamic Method.
    Nano letters, 2021, 11-10, Volume: 21, Issue:21

    Topics: Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Drug Resistance, Ne

2021
Circumventing Drug Resistance Pathways with a Nanoparticle-Based Photodynamic Method.
    Nano letters, 2021, 11-10, Volume: 21, Issue:21

    Topics: Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Drug Resistance, Ne

2021
Effect of long-term adjuvant temozolomide chemotherapy on primary glioblastoma patient survival.
    BMC neurology, 2021, Nov-02, Volume: 21, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant; Dacarbazine; Glioblastom

2021
Effect of long-term adjuvant temozolomide chemotherapy on primary glioblastoma patient survival.
    BMC neurology, 2021, Nov-02, Volume: 21, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant; Dacarbazine; Glioblastom

2021
Effect of long-term adjuvant temozolomide chemotherapy on primary glioblastoma patient survival.
    BMC neurology, 2021, Nov-02, Volume: 21, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant; Dacarbazine; Glioblastom

2021
Targeting glioblastoma signaling and metabolism with a re-purposed brain-penetrant drug.
    Cell reports, 2021, 11-02, Volume: 37, Issue:5

    Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Blood-Brain Barrier;

2021
Targeting glioblastoma signaling and metabolism with a re-purposed brain-penetrant drug.
    Cell reports, 2021, 11-02, Volume: 37, Issue:5

    Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Blood-Brain Barrier;

2021
Targeting glioblastoma signaling and metabolism with a re-purposed brain-penetrant drug.
    Cell reports, 2021, 11-02, Volume: 37, Issue:5

    Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Blood-Brain Barrier;

2021
Apcin inhibits the growth and invasion of glioblastoma cells and improves glioma sensitivity to temozolomide.
    Bioengineered, 2021, Volume: 12, Issue:2

    Topics: Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Carbamates; Cell Line, Tumor; Cell Pr

2021
Apcin inhibits the growth and invasion of glioblastoma cells and improves glioma sensitivity to temozolomide.
    Bioengineered, 2021, Volume: 12, Issue:2

    Topics: Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Carbamates; Cell Line, Tumor; Cell Pr

2021
Apcin inhibits the growth and invasion of glioblastoma cells and improves glioma sensitivity to temozolomide.
    Bioengineered, 2021, Volume: 12, Issue:2

    Topics: Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Carbamates; Cell Line, Tumor; Cell Pr

2021
FXYD2 mRNA expression represents a new independent factor that affects survival of glioma patients and predicts chemosensitivity of patients to temozolomide.
    BMC neurology, 2021, Nov-09, Volume: 21, Issue:1

    Topics: Brain Neoplasms; Glioma; Humans; Isocitrate Dehydrogenase; Mutation; Prognosis; RNA, Messenger; Sodi

2021
FXYD2 mRNA expression represents a new independent factor that affects survival of glioma patients and predicts chemosensitivity of patients to temozolomide.
    BMC neurology, 2021, Nov-09, Volume: 21, Issue:1

    Topics: Brain Neoplasms; Glioma; Humans; Isocitrate Dehydrogenase; Mutation; Prognosis; RNA, Messenger; Sodi

2021
FXYD2 mRNA expression represents a new independent factor that affects survival of glioma patients and predicts chemosensitivity of patients to temozolomide.
    BMC neurology, 2021, Nov-09, Volume: 21, Issue:1

    Topics: Brain Neoplasms; Glioma; Humans; Isocitrate Dehydrogenase; Mutation; Prognosis; RNA, Messenger; Sodi

2021
Exosome-Mediated Transfer of circ-
    Cancer biotherapy & radiopharmaceuticals, 2023, Volume: 38, Issue:1

    Topics: Animals; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Exosomes; Gene Expression

2023
Exosome-Mediated Transfer of circ-
    Cancer biotherapy & radiopharmaceuticals, 2023, Volume: 38, Issue:1

    Topics: Animals; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Exosomes; Gene Expression

2023
Exosome-Mediated Transfer of circ-
    Cancer biotherapy & radiopharmaceuticals, 2023, Volume: 38, Issue:1

    Topics: Animals; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Exosomes; Gene Expression

2023
Standard 6-week chemoradiation for elderly patients with newly diagnosed glioblastoma.
    Scientific reports, 2021, 11-11, Volume: 11, Issue:1

    Topics: Age Factors; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Female; Fo

2021
Standard 6-week chemoradiation for elderly patients with newly diagnosed glioblastoma.
    Scientific reports, 2021, 11-11, Volume: 11, Issue:1

    Topics: Age Factors; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Female; Fo

2021
Standard 6-week chemoradiation for elderly patients with newly diagnosed glioblastoma.
    Scientific reports, 2021, 11-11, Volume: 11, Issue:1

    Topics: Age Factors; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Female; Fo

2021
Olaparib Is a Mitochondrial Complex I Inhibitor That Kills Temozolomide-Resistant Human Glioblastoma Cells.
    International journal of molecular sciences, 2021, Nov-03, Volume: 22, Issue:21

    Topics: Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cell Proliferation; Drug Resistance,

2021
Olaparib Is a Mitochondrial Complex I Inhibitor That Kills Temozolomide-Resistant Human Glioblastoma Cells.
    International journal of molecular sciences, 2021, Nov-03, Volume: 22, Issue:21

    Topics: Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cell Proliferation; Drug Resistance,

2021
Olaparib Is a Mitochondrial Complex I Inhibitor That Kills Temozolomide-Resistant Human Glioblastoma Cells.
    International journal of molecular sciences, 2021, Nov-03, Volume: 22, Issue:21

    Topics: Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cell Proliferation; Drug Resistance,

2021
[MGMT and temozolomide sensibility].
    Bulletin du cancer, 2021, Volume: 108, Issue:12

    Topics: Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; DNA Methylation; DNA Mo

2021
[MGMT and temozolomide sensibility].
    Bulletin du cancer, 2021, Volume: 108, Issue:12

    Topics: Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; DNA Methylation; DNA Mo

2021
[MGMT and temozolomide sensibility].
    Bulletin du cancer, 2021, Volume: 108, Issue:12

    Topics: Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; DNA Methylation; DNA Mo

2021
Nanomedicine in the treatment of Glioblastoma.
    JPMA. The Journal of the Pakistan Medical Association, 2021, Volume: 71, Issue:11

    Topics: Antineoplastic Agents, Alkylating; Blood-Brain Barrier; Brain Neoplasms; Glioblastoma; Humans; Nanom

2021
Nanomedicine in the treatment of Glioblastoma.
    JPMA. The Journal of the Pakistan Medical Association, 2021, Volume: 71, Issue:11

    Topics: Antineoplastic Agents, Alkylating; Blood-Brain Barrier; Brain Neoplasms; Glioblastoma; Humans; Nanom

2021
Nanomedicine in the treatment of Glioblastoma.
    JPMA. The Journal of the Pakistan Medical Association, 2021, Volume: 71, Issue:11

    Topics: Antineoplastic Agents, Alkylating; Blood-Brain Barrier; Brain Neoplasms; Glioblastoma; Humans; Nanom

2021
Hematological adverse events in the management of glioblastoma.
    Journal of neuro-oncology, 2022, Volume: 156, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Glioblastoma; Humans; Randomized Controlled Tria

2022
Hematological adverse events in the management of glioblastoma.
    Journal of neuro-oncology, 2022, Volume: 156, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Glioblastoma; Humans; Randomized Controlled Tria

2022
Hematological adverse events in the management of glioblastoma.
    Journal of neuro-oncology, 2022, Volume: 156, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Glioblastoma; Humans; Randomized Controlled Tria

2022
Sporadic and Lynch syndrome-associated mismatch repair-deficient brain tumors.
    Laboratory investigation; a journal of technical methods and pathology, 2022, Volume: 102, Issue:2

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Biomarkers, Tumor; Brain; Brain Neoplasm

2022
Sporadic and Lynch syndrome-associated mismatch repair-deficient brain tumors.
    Laboratory investigation; a journal of technical methods and pathology, 2022, Volume: 102, Issue:2

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Biomarkers, Tumor; Brain; Brain Neoplasm

2022
Sporadic and Lynch syndrome-associated mismatch repair-deficient brain tumors.
    Laboratory investigation; a journal of technical methods and pathology, 2022, Volume: 102, Issue:2

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Biomarkers, Tumor; Brain; Brain Neoplasm

2022
Temporal Trends in Glioblastoma Survival: Progress then Plateau.
    The neurologist, 2022, May-01, Volume: 27, Issue:3

    Topics: Adult; Bevacizumab; Brain Neoplasms; Glioblastoma; Humans; Kaplan-Meier Estimate; Temozolomide

2022
Temporal Trends in Glioblastoma Survival: Progress then Plateau.
    The neurologist, 2022, May-01, Volume: 27, Issue:3

    Topics: Adult; Bevacizumab; Brain Neoplasms; Glioblastoma; Humans; Kaplan-Meier Estimate; Temozolomide

2022
Temporal Trends in Glioblastoma Survival: Progress then Plateau.
    The neurologist, 2022, May-01, Volume: 27, Issue:3

    Topics: Adult; Bevacizumab; Brain Neoplasms; Glioblastoma; Humans; Kaplan-Meier Estimate; Temozolomide

2022
RNA sequencing of glioblastoma tissue slice cultures reveals the effects of treatment at the transcriptional level.
    FEBS open bio, 2022, Volume: 12, Issue:2

    Topics: Brain Neoplasms; Exome Sequencing; Glioblastoma; Humans; Sequence Analysis, RNA; Temozolomide

2022
RNA sequencing of glioblastoma tissue slice cultures reveals the effects of treatment at the transcriptional level.
    FEBS open bio, 2022, Volume: 12, Issue:2

    Topics: Brain Neoplasms; Exome Sequencing; Glioblastoma; Humans; Sequence Analysis, RNA; Temozolomide

2022
RNA sequencing of glioblastoma tissue slice cultures reveals the effects of treatment at the transcriptional level.
    FEBS open bio, 2022, Volume: 12, Issue:2

    Topics: Brain Neoplasms; Exome Sequencing; Glioblastoma; Humans; Sequence Analysis, RNA; Temozolomide

2022
Accelerated hyper-versus normofractionated radiochemotherapy with temozolomide in patients with glioblastoma: a multicenter retrospective analysis.
    Journal of neuro-oncology, 2022, Volume: 156, Issue:2

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Follow-Up Studies; Frailty; G

2022
Accelerated hyper-versus normofractionated radiochemotherapy with temozolomide in patients with glioblastoma: a multicenter retrospective analysis.
    Journal of neuro-oncology, 2022, Volume: 156, Issue:2

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Follow-Up Studies; Frailty; G

2022
Accelerated hyper-versus normofractionated radiochemotherapy with temozolomide in patients with glioblastoma: a multicenter retrospective analysis.
    Journal of neuro-oncology, 2022, Volume: 156, Issue:2

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Follow-Up Studies; Frailty; G

2022
Small molecule based EGFR targeting of biodegradable nanoparticles containing temozolomide and Cy5 dye for greatly enhanced image-guided glioblastoma therapy.
    Nanomedicine : nanotechnology, biology, and medicine, 2022, Volume: 41

    Topics: Brain Neoplasms; Carbocyanines; Cell Line, Tumor; ErbB Receptors; Glioblastoma; Humans; Nanoparticle

2022
Small molecule based EGFR targeting of biodegradable nanoparticles containing temozolomide and Cy5 dye for greatly enhanced image-guided glioblastoma therapy.
    Nanomedicine : nanotechnology, biology, and medicine, 2022, Volume: 41

    Topics: Brain Neoplasms; Carbocyanines; Cell Line, Tumor; ErbB Receptors; Glioblastoma; Humans; Nanoparticle

2022
Small molecule based EGFR targeting of biodegradable nanoparticles containing temozolomide and Cy5 dye for greatly enhanced image-guided glioblastoma therapy.
    Nanomedicine : nanotechnology, biology, and medicine, 2022, Volume: 41

    Topics: Brain Neoplasms; Carbocyanines; Cell Line, Tumor; ErbB Receptors; Glioblastoma; Humans; Nanoparticle

2022
Interfering with mitochondrial dynamics sensitizes glioblastoma multiforme to temozolomide chemotherapy.
    Journal of cellular and molecular medicine, 2022, Volume: 26, Issue:3

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; Gli

2022
Interfering with mitochondrial dynamics sensitizes glioblastoma multiforme to temozolomide chemotherapy.
    Journal of cellular and molecular medicine, 2022, Volume: 26, Issue:3

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; Gli

2022
Interfering with mitochondrial dynamics sensitizes glioblastoma multiforme to temozolomide chemotherapy.
    Journal of cellular and molecular medicine, 2022, Volume: 26, Issue:3

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; Gli

2022
Combined intracranial Acriflavine, temozolomide and radiation extends survival in a rat glioma model.
    European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 2022, Volume: 170

    Topics: Absorbable Implants; Acriflavine; Animals; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cell Surviv

2022
Combined intracranial Acriflavine, temozolomide and radiation extends survival in a rat glioma model.
    European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 2022, Volume: 170

    Topics: Absorbable Implants; Acriflavine; Animals; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cell Surviv

2022
Combined intracranial Acriflavine, temozolomide and radiation extends survival in a rat glioma model.
    European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 2022, Volume: 170

    Topics: Absorbable Implants; Acriflavine; Animals; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cell Surviv

2022
Biochanin A Sensitizes Glioblastoma to Temozolomide by Inhibiting Autophagy.
    Molecular neurobiology, 2022, Volume: 59, Issue:2

    Topics: Autophagy; Brain Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; Genistein; Glioblastoma; Hu

2022
Biochanin A Sensitizes Glioblastoma to Temozolomide by Inhibiting Autophagy.
    Molecular neurobiology, 2022, Volume: 59, Issue:2

    Topics: Autophagy; Brain Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; Genistein; Glioblastoma; Hu

2022
Biochanin A Sensitizes Glioblastoma to Temozolomide by Inhibiting Autophagy.
    Molecular neurobiology, 2022, Volume: 59, Issue:2

    Topics: Autophagy; Brain Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; Genistein; Glioblastoma; Hu

2022
Inhibition of Carbonic Anhydrase 2 Overcomes Temozolomide Resistance in Glioblastoma Cells.
    International journal of molecular sciences, 2021, Dec-23, Volume: 23, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Autophagy; Brain Neoplasms; Carbonic Anhydrases; Cell Line, Tumor

2021
Inhibition of Carbonic Anhydrase 2 Overcomes Temozolomide Resistance in Glioblastoma Cells.
    International journal of molecular sciences, 2021, Dec-23, Volume: 23, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Autophagy; Brain Neoplasms; Carbonic Anhydrases; Cell Line, Tumor

2021
Inhibition of Carbonic Anhydrase 2 Overcomes Temozolomide Resistance in Glioblastoma Cells.
    International journal of molecular sciences, 2021, Dec-23, Volume: 23, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Autophagy; Brain Neoplasms; Carbonic Anhydrases; Cell Line, Tumor

2021
Dose-escalated accelerated hypofractionation for elderly or frail patients with a newly diagnosed glioblastoma.
    Journal of neuro-oncology, 2022, Volume: 156, Issue:2

    Topics: Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Female; Frail Elderly; Glioblastoma; Human

2022
Dose-escalated accelerated hypofractionation for elderly or frail patients with a newly diagnosed glioblastoma.
    Journal of neuro-oncology, 2022, Volume: 156, Issue:2

    Topics: Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Female; Frail Elderly; Glioblastoma; Human

2022
Dose-escalated accelerated hypofractionation for elderly or frail patients with a newly diagnosed glioblastoma.
    Journal of neuro-oncology, 2022, Volume: 156, Issue:2

    Topics: Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Female; Frail Elderly; Glioblastoma; Human

2022
GPR17 signaling activation by CHBC agonist induced cell death via modulation of MAPK pathway in glioblastoma.
    Life sciences, 2022, Feb-15, Volume: 291

    Topics: Antineoplastic Agents; Apoptosis; Brain Neoplasms; Cell Cycle Checkpoints; Cell Death; Cell Line, Tu

2022
GPR17 signaling activation by CHBC agonist induced cell death via modulation of MAPK pathway in glioblastoma.
    Life sciences, 2022, Feb-15, Volume: 291

    Topics: Antineoplastic Agents; Apoptosis; Brain Neoplasms; Cell Cycle Checkpoints; Cell Death; Cell Line, Tu

2022
GPR17 signaling activation by CHBC agonist induced cell death via modulation of MAPK pathway in glioblastoma.
    Life sciences, 2022, Feb-15, Volume: 291

    Topics: Antineoplastic Agents; Apoptosis; Brain Neoplasms; Cell Cycle Checkpoints; Cell Death; Cell Line, Tu

2022
Long-Acting Recombinant Human Interleukin-7, NT-I7, Increases Cytotoxic CD8 T Cells and Enhances Survival in Mouse Glioma Models.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2022, 03-15, Volume: 28, Issue:6

    Topics: Animals; Brain Neoplasms; CD8-Positive T-Lymphocytes; Cell Line, Tumor; Clinical Trials, Phase I as

2022
Long-Acting Recombinant Human Interleukin-7, NT-I7, Increases Cytotoxic CD8 T Cells and Enhances Survival in Mouse Glioma Models.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2022, 03-15, Volume: 28, Issue:6

    Topics: Animals; Brain Neoplasms; CD8-Positive T-Lymphocytes; Cell Line, Tumor; Clinical Trials, Phase I as

2022
Long-Acting Recombinant Human Interleukin-7, NT-I7, Increases Cytotoxic CD8 T Cells and Enhances Survival in Mouse Glioma Models.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2022, 03-15, Volume: 28, Issue:6

    Topics: Animals; Brain Neoplasms; CD8-Positive T-Lymphocytes; Cell Line, Tumor; Clinical Trials, Phase I as

2022
WNT signaling modulates chemoresistance to temozolomide in p53-mutant glioblastoma multiforme.
    Apoptosis : an international journal on programmed cell death, 2022, Volume: 27, Issue:1-2

    Topics: Animals; Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Drug Resis

2022
WNT signaling modulates chemoresistance to temozolomide in p53-mutant glioblastoma multiforme.
    Apoptosis : an international journal on programmed cell death, 2022, Volume: 27, Issue:1-2

    Topics: Animals; Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Drug Resis

2022
WNT signaling modulates chemoresistance to temozolomide in p53-mutant glioblastoma multiforme.
    Apoptosis : an international journal on programmed cell death, 2022, Volume: 27, Issue:1-2

    Topics: Animals; Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Drug Resis

2022
Temozolomide-induced myelotoxicity and single nucleotide polymorphisms in the MGMT gene in patients with adult diffuse glioma: a single-institutional pharmacogenetic study.
    Journal of neuro-oncology, 2022, Volume: 156, Issue:3

    Topics: Adult; Brain Neoplasms; DNA Modification Methylases; DNA Repair Enzymes; Glioma; Humans; Myeloid Cel

2022
Temozolomide-induced myelotoxicity and single nucleotide polymorphisms in the MGMT gene in patients with adult diffuse glioma: a single-institutional pharmacogenetic study.
    Journal of neuro-oncology, 2022, Volume: 156, Issue:3

    Topics: Adult; Brain Neoplasms; DNA Modification Methylases; DNA Repair Enzymes; Glioma; Humans; Myeloid Cel

2022
Temozolomide-induced myelotoxicity and single nucleotide polymorphisms in the MGMT gene in patients with adult diffuse glioma: a single-institutional pharmacogenetic study.
    Journal of neuro-oncology, 2022, Volume: 156, Issue:3

    Topics: Adult; Brain Neoplasms; DNA Modification Methylases; DNA Repair Enzymes; Glioma; Humans; Myeloid Cel

2022
Progressive multifocal leukoencephalopathy after first-line radiotherapy and temozolomide for glioblastoma.
    Neuro-oncology, 2022, 03-12, Volume: 24, Issue:3

    Topics: Brain Neoplasms; Glioblastoma; Humans; Leukoencephalopathy, Progressive Multifocal; Temozolomide

2022
Progressive multifocal leukoencephalopathy after first-line radiotherapy and temozolomide for glioblastoma.
    Neuro-oncology, 2022, 03-12, Volume: 24, Issue:3

    Topics: Brain Neoplasms; Glioblastoma; Humans; Leukoencephalopathy, Progressive Multifocal; Temozolomide

2022
Progressive multifocal leukoencephalopathy after first-line radiotherapy and temozolomide for glioblastoma.
    Neuro-oncology, 2022, 03-12, Volume: 24, Issue:3

    Topics: Brain Neoplasms; Glioblastoma; Humans; Leukoencephalopathy, Progressive Multifocal; Temozolomide

2022
Regulation of the Receptor Tyrosine Kinase AXL in Response to Therapy and Its Role in Therapy Resistance in Glioblastoma.
    International journal of molecular sciences, 2022, Jan-17, Volume: 23, Issue:2

    Topics: Axl Receptor Tyrosine Kinase; Benzocycloheptenes; Brain Neoplasms; Cell Line, Tumor; Cell Proliferat

2022
Regulation of the Receptor Tyrosine Kinase AXL in Response to Therapy and Its Role in Therapy Resistance in Glioblastoma.
    International journal of molecular sciences, 2022, Jan-17, Volume: 23, Issue:2

    Topics: Axl Receptor Tyrosine Kinase; Benzocycloheptenes; Brain Neoplasms; Cell Line, Tumor; Cell Proliferat

2022
Regulation of the Receptor Tyrosine Kinase AXL in Response to Therapy and Its Role in Therapy Resistance in Glioblastoma.
    International journal of molecular sciences, 2022, Jan-17, Volume: 23, Issue:2

    Topics: Axl Receptor Tyrosine Kinase; Benzocycloheptenes; Brain Neoplasms; Cell Line, Tumor; Cell Proliferat

2022
Quality of life following concurrent temozolomide-based chemoradiation therapy or observation in low-grade glioma.
    Journal of neuro-oncology, 2022, Volume: 156, Issue:3

    Topics: Adult; Brain Neoplasms; Chemoradiotherapy; Cross-Sectional Studies; Female; Glioma; Humans; Male; Mi

2022
Quality of life following concurrent temozolomide-based chemoradiation therapy or observation in low-grade glioma.
    Journal of neuro-oncology, 2022, Volume: 156, Issue:3

    Topics: Adult; Brain Neoplasms; Chemoradiotherapy; Cross-Sectional Studies; Female; Glioma; Humans; Male; Mi

2022
Quality of life following concurrent temozolomide-based chemoradiation therapy or observation in low-grade glioma.
    Journal of neuro-oncology, 2022, Volume: 156, Issue:3

    Topics: Adult; Brain Neoplasms; Chemoradiotherapy; Cross-Sectional Studies; Female; Glioma; Humans; Male; Mi

2022
MGMT promoter methylation determined by the MGMT-STP27 algorithm is not predictive for outcome to temozolomide in IDH-mutant anaplastic astrocytomas.
    Neuro-oncology, 2022, 04-01, Volume: 24, Issue:4

    Topics: Algorithms; Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neoplasms; DNA Methylation; DNA Mo

2022
MGMT promoter methylation determined by the MGMT-STP27 algorithm is not predictive for outcome to temozolomide in IDH-mutant anaplastic astrocytomas.
    Neuro-oncology, 2022, 04-01, Volume: 24, Issue:4

    Topics: Algorithms; Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neoplasms; DNA Methylation; DNA Mo

2022
MGMT promoter methylation determined by the MGMT-STP27 algorithm is not predictive for outcome to temozolomide in IDH-mutant anaplastic astrocytomas.
    Neuro-oncology, 2022, 04-01, Volume: 24, Issue:4

    Topics: Algorithms; Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neoplasms; DNA Methylation; DNA Mo

2022
Allopregnanolone suppresses glioblastoma survival through decreasing DPYSL3 and S100A11 expression.
    The Journal of steroid biochemistry and molecular biology, 2022, Volume: 219

    Topics: Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Drug Resistance, Ne

2022
Allopregnanolone suppresses glioblastoma survival through decreasing DPYSL3 and S100A11 expression.
    The Journal of steroid biochemistry and molecular biology, 2022, Volume: 219

    Topics: Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Drug Resistance, Ne

2022
Allopregnanolone suppresses glioblastoma survival through decreasing DPYSL3 and S100A11 expression.
    The Journal of steroid biochemistry and molecular biology, 2022, Volume: 219

    Topics: Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Drug Resistance, Ne

2022
Novel Imidazotetrazine Evades Known Resistance Mechanisms and Is Effective against Temozolomide-Resistant Brain Cancer in Cell Culture.
    ACS chemical biology, 2022, 02-18, Volume: 17, Issue:2

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Culture Techniques; Cell Line, Tum

2022
Novel Imidazotetrazine Evades Known Resistance Mechanisms and Is Effective against Temozolomide-Resistant Brain Cancer in Cell Culture.
    ACS chemical biology, 2022, 02-18, Volume: 17, Issue:2

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Culture Techniques; Cell Line, Tum

2022
Novel Imidazotetrazine Evades Known Resistance Mechanisms and Is Effective against Temozolomide-Resistant Brain Cancer in Cell Culture.
    ACS chemical biology, 2022, 02-18, Volume: 17, Issue:2

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Culture Techniques; Cell Line, Tum

2022
Disruption of DNA Repair and Survival Pathways through Heat Shock Protein Inhibition by Onalespib to Sensitize Malignant Gliomas to Chemoradiation Therapy.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2022, 05-02, Volume: 28, Issue:9

    Topics: Animals; Antineoplastic Agents; Benzamides; Brain Neoplasms; Cell Line, Tumor; DNA Repair; Glioblast

2022
Disruption of DNA Repair and Survival Pathways through Heat Shock Protein Inhibition by Onalespib to Sensitize Malignant Gliomas to Chemoradiation Therapy.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2022, 05-02, Volume: 28, Issue:9

    Topics: Animals; Antineoplastic Agents; Benzamides; Brain Neoplasms; Cell Line, Tumor; DNA Repair; Glioblast

2022
Disruption of DNA Repair and Survival Pathways through Heat Shock Protein Inhibition by Onalespib to Sensitize Malignant Gliomas to Chemoradiation Therapy.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2022, 05-02, Volume: 28, Issue:9

    Topics: Animals; Antineoplastic Agents; Benzamides; Brain Neoplasms; Cell Line, Tumor; DNA Repair; Glioblast

2022
Recurrent oligodendroglioma with changed 1p/19q status.
    Neuropathology : official journal of the Japanese Society of Neuropathology, 2022, Volume: 42, Issue:2

    Topics: Brain Neoplasms; Chromosome Aberrations; Chromosome Deletion; Chromosomes, Human, Pair 1; Chromosome

2022
Recurrent oligodendroglioma with changed 1p/19q status.
    Neuropathology : official journal of the Japanese Society of Neuropathology, 2022, Volume: 42, Issue:2

    Topics: Brain Neoplasms; Chromosome Aberrations; Chromosome Deletion; Chromosomes, Human, Pair 1; Chromosome

2022
Recurrent oligodendroglioma with changed 1p/19q status.
    Neuropathology : official journal of the Japanese Society of Neuropathology, 2022, Volume: 42, Issue:2

    Topics: Brain Neoplasms; Chromosome Aberrations; Chromosome Deletion; Chromosomes, Human, Pair 1; Chromosome

2022
Acquired temozolomide resistance in MGMT
    Cell death & disease, 2022, 02-10, Volume: 13, Issue:2

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; DNA Modification Methylases; D

2022
Acquired temozolomide resistance in MGMT
    Cell death & disease, 2022, 02-10, Volume: 13, Issue:2

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; DNA Modification Methylases; D

2022
Acquired temozolomide resistance in MGMT
    Cell death & disease, 2022, 02-10, Volume: 13, Issue:2

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; DNA Modification Methylases; D

2022
Up-Regulation of Cyclooxygenase-2 (COX-2) Expression by Temozolomide (TMZ) in Human Glioblastoma (GBM) Cell Lines.
    International journal of molecular sciences, 2022, Jan-28, Volume: 23, Issue:3

    Topics: Antineoplastic Agents, Alkylating; beta Catenin; Brain Neoplasms; Cell Line, Tumor; Cell Proliferati

2022
Up-Regulation of Cyclooxygenase-2 (COX-2) Expression by Temozolomide (TMZ) in Human Glioblastoma (GBM) Cell Lines.
    International journal of molecular sciences, 2022, Jan-28, Volume: 23, Issue:3

    Topics: Antineoplastic Agents, Alkylating; beta Catenin; Brain Neoplasms; Cell Line, Tumor; Cell Proliferati

2022
Up-Regulation of Cyclooxygenase-2 (COX-2) Expression by Temozolomide (TMZ) in Human Glioblastoma (GBM) Cell Lines.
    International journal of molecular sciences, 2022, Jan-28, Volume: 23, Issue:3

    Topics: Antineoplastic Agents, Alkylating; beta Catenin; Brain Neoplasms; Cell Line, Tumor; Cell Proliferati

2022
Synergy between TMZ and individualized multimodal immunotherapy to improve overall survival of IDH1 wild-type MGMT promoter-unmethylated GBM patients.
    Genes and immunity, 2022, Volume: 23, Issue:8

    Topics: Adult; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; DNA Methylation; DNA Modific

2022
Synergy between TMZ and individualized multimodal immunotherapy to improve overall survival of IDH1 wild-type MGMT promoter-unmethylated GBM patients.
    Genes and immunity, 2022, Volume: 23, Issue:8

    Topics: Adult; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; DNA Methylation; DNA Modific

2022
Synergy between TMZ and individualized multimodal immunotherapy to improve overall survival of IDH1 wild-type MGMT promoter-unmethylated GBM patients.
    Genes and immunity, 2022, Volume: 23, Issue:8

    Topics: Adult; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; DNA Methylation; DNA Modific

2022
CCL2 activates AKT signaling to promote glycolysis and chemoresistance in glioma cells.
    Cell biology international, 2022, Volume: 46, Issue:5

    Topics: Apoptosis; Brain Neoplasms; Cell Line, Tumor; Chemokine CCL2; Drug Resistance, Neoplasm; Glioma; Gly

2022
CCL2 activates AKT signaling to promote glycolysis and chemoresistance in glioma cells.
    Cell biology international, 2022, Volume: 46, Issue:5

    Topics: Apoptosis; Brain Neoplasms; Cell Line, Tumor; Chemokine CCL2; Drug Resistance, Neoplasm; Glioma; Gly

2022
CCL2 activates AKT signaling to promote glycolysis and chemoresistance in glioma cells.
    Cell biology international, 2022, Volume: 46, Issue:5

    Topics: Apoptosis; Brain Neoplasms; Cell Line, Tumor; Chemokine CCL2; Drug Resistance, Neoplasm; Glioma; Gly

2022
Molecular, Histological, and Clinical Characteristics of Oligodendrogliomas: A Multi-Institutional Retrospective Study.
    Neurosurgery, 2022, 05-01, Volume: 90, Issue:5

    Topics: Adult; Brain Neoplasms; Class I Phosphatidylinositol 3-Kinases; Female; Humans; Male; Oligodendrogli

2022
Molecular, Histological, and Clinical Characteristics of Oligodendrogliomas: A Multi-Institutional Retrospective Study.
    Neurosurgery, 2022, 05-01, Volume: 90, Issue:5

    Topics: Adult; Brain Neoplasms; Class I Phosphatidylinositol 3-Kinases; Female; Humans; Male; Oligodendrogli

2022
Molecular, Histological, and Clinical Characteristics of Oligodendrogliomas: A Multi-Institutional Retrospective Study.
    Neurosurgery, 2022, 05-01, Volume: 90, Issue:5

    Topics: Adult; Brain Neoplasms; Class I Phosphatidylinositol 3-Kinases; Female; Humans; Male; Oligodendrogli

2022
Tumor treating fields therapy is feasible and safe in a 3-year-old patient with diffuse midline glioma H3K27M - a case report.
    Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 2022, Volume: 38, Issue:9

    Topics: Adult; Brain Neoplasms; Child; Child, Preschool; Combined Modality Therapy; Electric Stimulation The

2022
Tumor treating fields therapy is feasible and safe in a 3-year-old patient with diffuse midline glioma H3K27M - a case report.
    Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 2022, Volume: 38, Issue:9

    Topics: Adult; Brain Neoplasms; Child; Child, Preschool; Combined Modality Therapy; Electric Stimulation The

2022
Tumor treating fields therapy is feasible and safe in a 3-year-old patient with diffuse midline glioma H3K27M - a case report.
    Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 2022, Volume: 38, Issue:9

    Topics: Adult; Brain Neoplasms; Child; Child, Preschool; Combined Modality Therapy; Electric Stimulation The

2022
Recycling of SLC38A1 to the plasma membrane by DSCR3 promotes acquired temozolomide resistance in glioblastoma.
    Journal of neuro-oncology, 2022, Volume: 157, Issue:1

    Topics: Amino Acid Transport System A; Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Lin

2022
Recycling of SLC38A1 to the plasma membrane by DSCR3 promotes acquired temozolomide resistance in glioblastoma.
    Journal of neuro-oncology, 2022, Volume: 157, Issue:1

    Topics: Amino Acid Transport System A; Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Lin

2022
Recycling of SLC38A1 to the plasma membrane by DSCR3 promotes acquired temozolomide resistance in glioblastoma.
    Journal of neuro-oncology, 2022, Volume: 157, Issue:1

    Topics: Amino Acid Transport System A; Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Lin

2022
Nek1-inhibitor and temozolomide-loaded microfibers as a co-therapy strategy for glioblastoma treatment.
    International journal of pharmaceutics, 2022, Apr-05, Volume: 617

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Cell Survival; Gliobl

2022
Nek1-inhibitor and temozolomide-loaded microfibers as a co-therapy strategy for glioblastoma treatment.
    International journal of pharmaceutics, 2022, Apr-05, Volume: 617

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Cell Survival; Gliobl

2022
Nek1-inhibitor and temozolomide-loaded microfibers as a co-therapy strategy for glioblastoma treatment.
    International journal of pharmaceutics, 2022, Apr-05, Volume: 617

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Cell Survival; Gliobl

2022
Hsa_circ_0072309 enhances autophagy and TMZ sensitivity in glioblastoma.
    CNS neuroscience & therapeutics, 2022, Volume: 28, Issue:6

    Topics: Apoptosis; Autophagy; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Gene Expression Regulat

2022
Hsa_circ_0072309 enhances autophagy and TMZ sensitivity in glioblastoma.
    CNS neuroscience & therapeutics, 2022, Volume: 28, Issue:6

    Topics: Apoptosis; Autophagy; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Gene Expression Regulat

2022
Hsa_circ_0072309 enhances autophagy and TMZ sensitivity in glioblastoma.
    CNS neuroscience & therapeutics, 2022, Volume: 28, Issue:6

    Topics: Apoptosis; Autophagy; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Gene Expression Regulat

2022
The Different Temozolomide Effects on Tumorigenesis Mechanisms of Pediatric Glioblastoma PBT24 and SF8628 Cell Tumor in CAM Model and on Cells In Vitro.
    International journal of molecular sciences, 2022, Feb-11, Volume: 23, Issue:4

    Topics: Animals; Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Carcinogenesis; Cell Line, T

2022
The Different Temozolomide Effects on Tumorigenesis Mechanisms of Pediatric Glioblastoma PBT24 and SF8628 Cell Tumor in CAM Model and on Cells In Vitro.
    International journal of molecular sciences, 2022, Feb-11, Volume: 23, Issue:4

    Topics: Animals; Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Carcinogenesis; Cell Line, T

2022
The Different Temozolomide Effects on Tumorigenesis Mechanisms of Pediatric Glioblastoma PBT24 and SF8628 Cell Tumor in CAM Model and on Cells In Vitro.
    International journal of molecular sciences, 2022, Feb-11, Volume: 23, Issue:4

    Topics: Animals; Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Carcinogenesis; Cell Line, T

2022
CRB2 enhances malignancy of glioblastoma via activation of the NF-κB pathway.
    Experimental cell research, 2022, 05-01, Volume: 414, Issue:1

    Topics: Brain Neoplasms; Carrier Proteins; Cell Line, Tumor; Gene Expression Regulation, Neoplastic; Gliobla

2022
CRB2 enhances malignancy of glioblastoma via activation of the NF-κB pathway.
    Experimental cell research, 2022, 05-01, Volume: 414, Issue:1

    Topics: Brain Neoplasms; Carrier Proteins; Cell Line, Tumor; Gene Expression Regulation, Neoplastic; Gliobla

2022
CRB2 enhances malignancy of glioblastoma via activation of the NF-κB pathway.
    Experimental cell research, 2022, 05-01, Volume: 414, Issue:1

    Topics: Brain Neoplasms; Carrier Proteins; Cell Line, Tumor; Gene Expression Regulation, Neoplastic; Gliobla

2022
Inhibition of ATP hydrolysis as a key regulator of temozolomide resistance and migratory phenotype of glioblastoma cells.
    Biochemical and biophysical research communications, 2022, 04-23, Volume: 601

    Topics: Adenosine Triphosphatases; Adenosine Triphosphate; Antineoplastic Agents, Alkylating; Brain Neoplasm

2022
Inhibition of ATP hydrolysis as a key regulator of temozolomide resistance and migratory phenotype of glioblastoma cells.
    Biochemical and biophysical research communications, 2022, 04-23, Volume: 601

    Topics: Adenosine Triphosphatases; Adenosine Triphosphate; Antineoplastic Agents, Alkylating; Brain Neoplasm

2022
Inhibition of ATP hydrolysis as a key regulator of temozolomide resistance and migratory phenotype of glioblastoma cells.
    Biochemical and biophysical research communications, 2022, 04-23, Volume: 601

    Topics: Adenosine Triphosphatases; Adenosine Triphosphate; Antineoplastic Agents, Alkylating; Brain Neoplasm

2022
RBBP4-p300 axis modulates expression of genes essential for cell survival and is a potential target for therapy in glioblastoma.
    Neuro-oncology, 2022, 08-01, Volume: 24, Issue:8

    Topics: Acetylation; Animals; Brain Neoplasms; Cell Line, Tumor; Cell Survival; Drug Resistance, Neoplasm; E

2022
RBBP4-p300 axis modulates expression of genes essential for cell survival and is a potential target for therapy in glioblastoma.
    Neuro-oncology, 2022, 08-01, Volume: 24, Issue:8

    Topics: Acetylation; Animals; Brain Neoplasms; Cell Line, Tumor; Cell Survival; Drug Resistance, Neoplasm; E

2022
RBBP4-p300 axis modulates expression of genes essential for cell survival and is a potential target for therapy in glioblastoma.
    Neuro-oncology, 2022, 08-01, Volume: 24, Issue:8

    Topics: Acetylation; Animals; Brain Neoplasms; Cell Line, Tumor; Cell Survival; Drug Resistance, Neoplasm; E

2022
Anti-glioblastoma effects of phenolic variants of benzoylphenoxyacetamide (BPA) with high potential for blood brain barrier penetration.
    Scientific reports, 2022, 03-01, Volume: 12, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Blood-Brain Barrier; Brain Neoplasms; Endothelial Cells; Glioblas

2022
Anti-glioblastoma effects of phenolic variants of benzoylphenoxyacetamide (BPA) with high potential for blood brain barrier penetration.
    Scientific reports, 2022, 03-01, Volume: 12, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Blood-Brain Barrier; Brain Neoplasms; Endothelial Cells; Glioblas

2022
Anti-glioblastoma effects of phenolic variants of benzoylphenoxyacetamide (BPA) with high potential for blood brain barrier penetration.
    Scientific reports, 2022, 03-01, Volume: 12, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Blood-Brain Barrier; Brain Neoplasms; Endothelial Cells; Glioblas

2022
Antitumor Activity of a Mitochondrial-Targeted HSP90 Inhibitor in Gliomas.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2022, 05-13, Volume: 28, Issue:10

    Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Cell Line, Tumor; Glioma; Humans; Mice; Mitochondri

2022
Antitumor Activity of a Mitochondrial-Targeted HSP90 Inhibitor in Gliomas.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2022, 05-13, Volume: 28, Issue:10

    Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Cell Line, Tumor; Glioma; Humans; Mice; Mitochondri

2022
Antitumor Activity of a Mitochondrial-Targeted HSP90 Inhibitor in Gliomas.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2022, 05-13, Volume: 28, Issue:10

    Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Cell Line, Tumor; Glioma; Humans; Mice; Mitochondri

2022
Efficacy of Temozolomide-Conjugated Gold Nanoparticle Photothermal Therapy of Drug-Resistant Glioblastoma and Its Mechanism Study.
    Molecular pharmaceutics, 2022, 04-04, Volume: 19, Issue:4

    Topics: Animals; Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Drug Resis

2022
Efficacy of Temozolomide-Conjugated Gold Nanoparticle Photothermal Therapy of Drug-Resistant Glioblastoma and Its Mechanism Study.
    Molecular pharmaceutics, 2022, 04-04, Volume: 19, Issue:4

    Topics: Animals; Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Drug Resis

2022
Efficacy of Temozolomide-Conjugated Gold Nanoparticle Photothermal Therapy of Drug-Resistant Glioblastoma and Its Mechanism Study.
    Molecular pharmaceutics, 2022, 04-04, Volume: 19, Issue:4

    Topics: Animals; Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Drug Resis

2022
Regorafenib Reverses Temozolomide-Induced CXCL12/CXCR4 Signaling and Triggers Apoptosis Mechanism in Glioblastoma.
    Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics, 2022, Volume: 19, Issue:2

    Topics: Animals; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Chemokine CXCL12; Glioblastoma; Humans; NF-ka

2022
Regorafenib Reverses Temozolomide-Induced CXCL12/CXCR4 Signaling and Triggers Apoptosis Mechanism in Glioblastoma.
    Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics, 2022, Volume: 19, Issue:2

    Topics: Animals; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Chemokine CXCL12; Glioblastoma; Humans; NF-ka

2022
Regorafenib Reverses Temozolomide-Induced CXCL12/CXCR4 Signaling and Triggers Apoptosis Mechanism in Glioblastoma.
    Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics, 2022, Volume: 19, Issue:2

    Topics: Animals; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Chemokine CXCL12; Glioblastoma; Humans; NF-ka

2022
Contrast enhancing pattern on pre-treatment MRI predicts response to anti-angiogenic treatment in recurrent glioblastoma: comparison of bevacizumab and temozolomide treatment.
    Journal of neuro-oncology, 2022, Volume: 157, Issue:3

    Topics: Bevacizumab; Brain Neoplasms; Glioblastoma; Humans; Magnetic Resonance Imaging; Neoplasm Recurrence,

2022
Contrast enhancing pattern on pre-treatment MRI predicts response to anti-angiogenic treatment in recurrent glioblastoma: comparison of bevacizumab and temozolomide treatment.
    Journal of neuro-oncology, 2022, Volume: 157, Issue:3

    Topics: Bevacizumab; Brain Neoplasms; Glioblastoma; Humans; Magnetic Resonance Imaging; Neoplasm Recurrence,

2022
Contrast enhancing pattern on pre-treatment MRI predicts response to anti-angiogenic treatment in recurrent glioblastoma: comparison of bevacizumab and temozolomide treatment.
    Journal of neuro-oncology, 2022, Volume: 157, Issue:3

    Topics: Bevacizumab; Brain Neoplasms; Glioblastoma; Humans; Magnetic Resonance Imaging; Neoplasm Recurrence,

2022
Inhibition of TRPM7 with carvacrol suppresses glioblastoma functions in vivo.
    The European journal of neuroscience, 2022, Volume: 55, Issue:6

    Topics: Animals; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Cymenes; Glioblastoma; Humans; Mice;

2022
Inhibition of TRPM7 with carvacrol suppresses glioblastoma functions in vivo.
    The European journal of neuroscience, 2022, Volume: 55, Issue:6

    Topics: Animals; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Cymenes; Glioblastoma; Humans; Mice;

2022
Inhibition of TRPM7 with carvacrol suppresses glioblastoma functions in vivo.
    The European journal of neuroscience, 2022, Volume: 55, Issue:6

    Topics: Animals; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Cymenes; Glioblastoma; Humans; Mice;

2022
The RNA-binding protein fragile-X mental retardation autosomal 1 (FXR1) modulates glioma cells sensitivity to temozolomide by regulating ferroptosis.
    Biochemical and biophysical research communications, 2022, 05-07, Volume: 603

    Topics: Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation;

2022
The RNA-binding protein fragile-X mental retardation autosomal 1 (FXR1) modulates glioma cells sensitivity to temozolomide by regulating ferroptosis.
    Biochemical and biophysical research communications, 2022, 05-07, Volume: 603

    Topics: Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation;

2022
The RNA-binding protein fragile-X mental retardation autosomal 1 (FXR1) modulates glioma cells sensitivity to temozolomide by regulating ferroptosis.
    Biochemical and biophysical research communications, 2022, 05-07, Volume: 603

    Topics: Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation;

2022
Evaluating Quality Indicators of Glioblastoma Care: Audit Results From an Indian Tertiary Care Cancer Center.
    JCO global oncology, 2022, Volume: 8

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Glioblastoma; Humans; Male; Middle

2022
Evaluating Quality Indicators of Glioblastoma Care: Audit Results From an Indian Tertiary Care Cancer Center.
    JCO global oncology, 2022, Volume: 8

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Glioblastoma; Humans; Male; Middle

2022
Evaluating Quality Indicators of Glioblastoma Care: Audit Results From an Indian Tertiary Care Cancer Center.
    JCO global oncology, 2022, Volume: 8

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Glioblastoma; Humans; Male; Middle

2022
Prognostic significance of therapy-induced myelosuppression in newly diagnosed glioblastoma.
    Neuro-oncology, 2022, 09-01, Volume: 24, Issue:9

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Female; Glioblastoma; Humans;

2022
Prognostic significance of therapy-induced myelosuppression in newly diagnosed glioblastoma.
    Neuro-oncology, 2022, 09-01, Volume: 24, Issue:9

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Female; Glioblastoma; Humans;

2022
Prognostic significance of therapy-induced myelosuppression in newly diagnosed glioblastoma.
    Neuro-oncology, 2022, 09-01, Volume: 24, Issue:9

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Female; Glioblastoma; Humans;

2022
Poly-guanidine shows high cytotoxicity in glioma cell cultures and glioma stem cells.
    Investigational new drugs, 2022, Volume: 40, Issue:3

    Topics: Brain Neoplasms; Cell Culture Techniques; Cell Line, Tumor; Drug Resistance, Neoplasm; Glioblastoma;

2022
Poly-guanidine shows high cytotoxicity in glioma cell cultures and glioma stem cells.
    Investigational new drugs, 2022, Volume: 40, Issue:3

    Topics: Brain Neoplasms; Cell Culture Techniques; Cell Line, Tumor; Drug Resistance, Neoplasm; Glioblastoma;

2022
Poly-guanidine shows high cytotoxicity in glioma cell cultures and glioma stem cells.
    Investigational new drugs, 2022, Volume: 40, Issue:3

    Topics: Brain Neoplasms; Cell Culture Techniques; Cell Line, Tumor; Drug Resistance, Neoplasm; Glioblastoma;

2022
Polyunsaturated Fatty Acid-Enriched Lipid Fingerprint of Glioblastoma Proliferative Regions Is Differentially Regulated According to Glioblastoma Molecular Subtype.
    International journal of molecular sciences, 2022, Mar-09, Volume: 23, Issue:6

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; Fat

2022
Polyunsaturated Fatty Acid-Enriched Lipid Fingerprint of Glioblastoma Proliferative Regions Is Differentially Regulated According to Glioblastoma Molecular Subtype.
    International journal of molecular sciences, 2022, Mar-09, Volume: 23, Issue:6

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; Fat

2022
Polyunsaturated Fatty Acid-Enriched Lipid Fingerprint of Glioblastoma Proliferative Regions Is Differentially Regulated According to Glioblastoma Molecular Subtype.
    International journal of molecular sciences, 2022, Mar-09, Volume: 23, Issue:6

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; Fat

2022
DNA methylation-based age acceleration observed in IDH wild-type glioblastoma is associated with better outcome-including in elderly patients.
    Acta neuropathologica communications, 2022, 03-24, Volume: 10, Issue:1

    Topics: Acceleration; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; DNA Methylation; DNA Modific

2022
DNA methylation-based age acceleration observed in IDH wild-type glioblastoma is associated with better outcome-including in elderly patients.
    Acta neuropathologica communications, 2022, 03-24, Volume: 10, Issue:1

    Topics: Acceleration; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; DNA Methylation; DNA Modific

2022
DNA methylation-based age acceleration observed in IDH wild-type glioblastoma is associated with better outcome-including in elderly patients.
    Acta neuropathologica communications, 2022, 03-24, Volume: 10, Issue:1

    Topics: Acceleration; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; DNA Methylation; DNA Modific

2022
Heme Oxygenase-1 targeting exosomes for temozolomide resistant glioblastoma synergistic therapy.
    Journal of controlled release : official journal of the Controlled Release Society, 2022, Volume: 345

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; Exo

2022
Heme Oxygenase-1 targeting exosomes for temozolomide resistant glioblastoma synergistic therapy.
    Journal of controlled release : official journal of the Controlled Release Society, 2022, Volume: 345

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; Exo

2022
Heme Oxygenase-1 targeting exosomes for temozolomide resistant glioblastoma synergistic therapy.
    Journal of controlled release : official journal of the Controlled Release Society, 2022, Volume: 345

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; Exo

2022
Sex-Dependent Analysis of Temozolomide-Induced Myelosuppression and Effects on Survival in a Large Real-life Cohort of Patients With Glioma.
    Neurology, 2022, 05-17, Volume: 98, Issue:20

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Female; Glioma; Humans; Male; Retrospective Stud

2022
Sex-Dependent Analysis of Temozolomide-Induced Myelosuppression and Effects on Survival in a Large Real-life Cohort of Patients With Glioma.
    Neurology, 2022, 05-17, Volume: 98, Issue:20

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Female; Glioma; Humans; Male; Retrospective Stud

2022
Sex-Dependent Analysis of Temozolomide-Induced Myelosuppression and Effects on Survival in a Large Real-life Cohort of Patients With Glioma.
    Neurology, 2022, 05-17, Volume: 98, Issue:20

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Female; Glioma; Humans; Male; Retrospective Stud

2022
Inhibitory effects of temozolomide on glioma cells is sensitized by RSL3-induced ferroptosis but negatively correlated with expression of ferritin heavy chain 1 and ferritin light chain.
    Laboratory investigation; a journal of technical methods and pathology, 2022, Volume: 102, Issue:7

    Topics: Animals; Apoferritins; Brain Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; Ferroptosis; Gl

2022
Inhibitory effects of temozolomide on glioma cells is sensitized by RSL3-induced ferroptosis but negatively correlated with expression of ferritin heavy chain 1 and ferritin light chain.
    Laboratory investigation; a journal of technical methods and pathology, 2022, Volume: 102, Issue:7

    Topics: Animals; Apoferritins; Brain Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; Ferroptosis; Gl

2022
Inhibitory effects of temozolomide on glioma cells is sensitized by RSL3-induced ferroptosis but negatively correlated with expression of ferritin heavy chain 1 and ferritin light chain.
    Laboratory investigation; a journal of technical methods and pathology, 2022, Volume: 102, Issue:7

    Topics: Animals; Apoferritins; Brain Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; Ferroptosis; Gl

2022
TMZ magnetic temperature-sensitive liposomes-mediated magnetothermal chemotherapy induces pyroptosis in glioblastoma.
    Nanomedicine : nanotechnology, biology, and medicine, 2022, Volume: 43

    Topics: Apoptosis; Brain Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; Glioblastoma; Humans; Lipos

2022
TMZ magnetic temperature-sensitive liposomes-mediated magnetothermal chemotherapy induces pyroptosis in glioblastoma.
    Nanomedicine : nanotechnology, biology, and medicine, 2022, Volume: 43

    Topics: Apoptosis; Brain Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; Glioblastoma; Humans; Lipos

2022
TMZ magnetic temperature-sensitive liposomes-mediated magnetothermal chemotherapy induces pyroptosis in glioblastoma.
    Nanomedicine : nanotechnology, biology, and medicine, 2022, Volume: 43

    Topics: Apoptosis; Brain Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; Glioblastoma; Humans; Lipos

2022
Class I HDAC overexpression promotes temozolomide resistance in glioma cells by regulating RAD18 expression.
    Cell death & disease, 2022, 04-01, Volume: 13, Issue:4

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; DNA-Binding Proteins; Drug Res

2022
Class I HDAC overexpression promotes temozolomide resistance in glioma cells by regulating RAD18 expression.
    Cell death & disease, 2022, 04-01, Volume: 13, Issue:4

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; DNA-Binding Proteins; Drug Res

2022
Class I HDAC overexpression promotes temozolomide resistance in glioma cells by regulating RAD18 expression.
    Cell death & disease, 2022, 04-01, Volume: 13, Issue:4

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; DNA-Binding Proteins; Drug Res

2022
PSMG3-AS1 enhances glioma resistance to temozolomide via stabilizing c-Myc in the nucleus.
    Brain and behavior, 2022, Volume: 12, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Drug Resis

2022
PSMG3-AS1 enhances glioma resistance to temozolomide via stabilizing c-Myc in the nucleus.
    Brain and behavior, 2022, Volume: 12, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Drug Resis

2022
PSMG3-AS1 enhances glioma resistance to temozolomide via stabilizing c-Myc in the nucleus.
    Brain and behavior, 2022, Volume: 12, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Drug Resis

2022
Concomitant Temozolomide plus radiotherapy for high-grade and recurrent meningioma: a retrospective chart review.
    BMC cancer, 2022, Apr-07, Volume: 22, Issue:1

    Topics: Brain Neoplasms; Child; Humans; Meningeal Neoplasms; Meningioma; Neoplasm Recurrence, Local; Retrosp

2022
Concomitant Temozolomide plus radiotherapy for high-grade and recurrent meningioma: a retrospective chart review.
    BMC cancer, 2022, Apr-07, Volume: 22, Issue:1

    Topics: Brain Neoplasms; Child; Humans; Meningeal Neoplasms; Meningioma; Neoplasm Recurrence, Local; Retrosp

2022
Concomitant Temozolomide plus radiotherapy for high-grade and recurrent meningioma: a retrospective chart review.
    BMC cancer, 2022, Apr-07, Volume: 22, Issue:1

    Topics: Brain Neoplasms; Child; Humans; Meningeal Neoplasms; Meningioma; Neoplasm Recurrence, Local; Retrosp

2022
    Disease markers, 2022, Volume: 2022

    Topics: Brain Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; Forkhead Transcription Factors; Gliobl

2022
    Disease markers, 2022, Volume: 2022

    Topics: Brain Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; Forkhead Transcription Factors; Gliobl

2022
    Disease markers, 2022, Volume: 2022

    Topics: Brain Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; Forkhead Transcription Factors; Gliobl

2022
Serum-derived extracellular vesicles facilitate temozolomide resistance in glioblastoma through a HOTAIR-dependent mechanism.
    Cell death & disease, 2022, 04-13, Volume: 13, Issue:4

    Topics: Brain Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; Extracellular Vesicles; Glioblastoma;

2022
Serum-derived extracellular vesicles facilitate temozolomide resistance in glioblastoma through a HOTAIR-dependent mechanism.
    Cell death & disease, 2022, 04-13, Volume: 13, Issue:4

    Topics: Brain Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; Extracellular Vesicles; Glioblastoma;

2022
Serum-derived extracellular vesicles facilitate temozolomide resistance in glioblastoma through a HOTAIR-dependent mechanism.
    Cell death & disease, 2022, 04-13, Volume: 13, Issue:4

    Topics: Brain Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; Extracellular Vesicles; Glioblastoma;

2022
LINC01564 Promotes the TMZ Resistance of Glioma Cells by Upregulating NFE2L2 Expression to Inhibit Ferroptosis.
    Molecular neurobiology, 2022, Volume: 59, Issue:6

    Topics: Animals; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Drug Resistance, Neoplasm

2022
LINC01564 Promotes the TMZ Resistance of Glioma Cells by Upregulating NFE2L2 Expression to Inhibit Ferroptosis.
    Molecular neurobiology, 2022, Volume: 59, Issue:6

    Topics: Animals; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Drug Resistance, Neoplasm

2022
LINC01564 Promotes the TMZ Resistance of Glioma Cells by Upregulating NFE2L2 Expression to Inhibit Ferroptosis.
    Molecular neurobiology, 2022, Volume: 59, Issue:6

    Topics: Animals; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Drug Resistance, Neoplasm

2022
Cost Effectiveness of
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2022, Volume: 63, Issue:11

    Topics: Brain Neoplasms; Cost-Benefit Analysis; Glioma; Humans; Magnetic Resonance Imaging; Positron-Emissio

2022
Cost Effectiveness of
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2022, Volume: 63, Issue:11

    Topics: Brain Neoplasms; Cost-Benefit Analysis; Glioma; Humans; Magnetic Resonance Imaging; Positron-Emissio

2022
Cost Effectiveness of
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2022, Volume: 63, Issue:11

    Topics: Brain Neoplasms; Cost-Benefit Analysis; Glioma; Humans; Magnetic Resonance Imaging; Positron-Emissio

2022
Integrative analysis of therapy resistance and transcriptomic profiling data in glioblastoma cells identifies sensitization vulnerabilities for combined modality radiochemotherapy.
    Radiation oncology (London, England), 2022, Apr-19, Volume: 17, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Chemoradiotherapy; Combined Mo

2022
Integrative analysis of therapy resistance and transcriptomic profiling data in glioblastoma cells identifies sensitization vulnerabilities for combined modality radiochemotherapy.
    Radiation oncology (London, England), 2022, Apr-19, Volume: 17, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Chemoradiotherapy; Combined Mo

2022
Integrative analysis of therapy resistance and transcriptomic profiling data in glioblastoma cells identifies sensitization vulnerabilities for combined modality radiochemotherapy.
    Radiation oncology (London, England), 2022, Apr-19, Volume: 17, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Chemoradiotherapy; Combined Mo

2022
PET With 11C-Methyl-l-Methionine as a Predictor of Consequential Outcomes at the Time of Discontinuing Temozolomide-Adjuvant Chemotherapy in Patients With Residual IDH-Mutant Lower-Grade Glioma.
    Clinical nuclear medicine, 2022, Jul-01, Volume: 47, Issue:7

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Carbon Radioisotopes; Chemotherapy, Adjuvant; Di

2022
PET With 11C-Methyl-l-Methionine as a Predictor of Consequential Outcomes at the Time of Discontinuing Temozolomide-Adjuvant Chemotherapy in Patients With Residual IDH-Mutant Lower-Grade Glioma.
    Clinical nuclear medicine, 2022, Jul-01, Volume: 47, Issue:7

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Carbon Radioisotopes; Chemotherapy, Adjuvant; Di

2022
PET With 11C-Methyl-l-Methionine as a Predictor of Consequential Outcomes at the Time of Discontinuing Temozolomide-Adjuvant Chemotherapy in Patients With Residual IDH-Mutant Lower-Grade Glioma.
    Clinical nuclear medicine, 2022, Jul-01, Volume: 47, Issue:7

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Carbon Radioisotopes; Chemotherapy, Adjuvant; Di

2022
Current trend of radiotherapy for glioblastoma in the elderly: a survey study by the brain tumor Committee of the Korean Radiation Oncology Group (KROG 21-05).
    Japanese journal of clinical oncology, 2022, 08-05, Volume: 52, Issue:8

    Topics: Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Glioblastoma; Humans; Republi

2022
Current trend of radiotherapy for glioblastoma in the elderly: a survey study by the brain tumor Committee of the Korean Radiation Oncology Group (KROG 21-05).
    Japanese journal of clinical oncology, 2022, 08-05, Volume: 52, Issue:8

    Topics: Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Glioblastoma; Humans; Republi

2022
Current trend of radiotherapy for glioblastoma in the elderly: a survey study by the brain tumor Committee of the Korean Radiation Oncology Group (KROG 21-05).
    Japanese journal of clinical oncology, 2022, 08-05, Volume: 52, Issue:8

    Topics: Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Glioblastoma; Humans; Republi

2022
Tryptophan hydroxylase 1 drives glioma progression by modulating the serotonin/L1CAM/NF-κB signaling pathway.
    BMC cancer, 2022, Apr-26, Volume: 22, Issue:1

    Topics: Animals; Brain Neoplasms; Cell Line, Tumor; Glioma; Humans; Mice; Neural Cell Adhesion Molecule L1;

2022
Tryptophan hydroxylase 1 drives glioma progression by modulating the serotonin/L1CAM/NF-κB signaling pathway.
    BMC cancer, 2022, Apr-26, Volume: 22, Issue:1

    Topics: Animals; Brain Neoplasms; Cell Line, Tumor; Glioma; Humans; Mice; Neural Cell Adhesion Molecule L1;

2022
Tryptophan hydroxylase 1 drives glioma progression by modulating the serotonin/L1CAM/NF-κB signaling pathway.
    BMC cancer, 2022, Apr-26, Volume: 22, Issue:1

    Topics: Animals; Brain Neoplasms; Cell Line, Tumor; Glioma; Humans; Mice; Neural Cell Adhesion Molecule L1;

2022
Survival outcomes associated with MGMT promoter methylation and temozolomide in gliosarcoma patients.
    Journal of neuro-oncology, 2022, Volume: 158, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; DNA Methylation; DNA Modification M

2022
Survival outcomes associated with MGMT promoter methylation and temozolomide in gliosarcoma patients.
    Journal of neuro-oncology, 2022, Volume: 158, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; DNA Methylation; DNA Modification M

2022
Survival outcomes associated with MGMT promoter methylation and temozolomide in gliosarcoma patients.
    Journal of neuro-oncology, 2022, Volume: 158, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; DNA Methylation; DNA Modification M

2022
Cognitive function after concurrent temozolomide-based chemoradiation therapy in low-grade gliomas.
    Journal of neuro-oncology, 2022, Volume: 158, Issue:3

    Topics: Adult; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cognition; Female; Glioma; Humans; Male;

2022
Cognitive function after concurrent temozolomide-based chemoradiation therapy in low-grade gliomas.
    Journal of neuro-oncology, 2022, Volume: 158, Issue:3

    Topics: Adult; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cognition; Female; Glioma; Humans; Male;

2022
Cognitive function after concurrent temozolomide-based chemoradiation therapy in low-grade gliomas.
    Journal of neuro-oncology, 2022, Volume: 158, Issue:3

    Topics: Adult; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cognition; Female; Glioma; Humans; Male;

2022
Tumor-derived exosomes reversing TMZ resistance by synergistic drug delivery for glioma-targeting treatment.
    Colloids and surfaces. B, Biointerfaces, 2022, Volume: 215

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; Exo

2022
Tumor-derived exosomes reversing TMZ resistance by synergistic drug delivery for glioma-targeting treatment.
    Colloids and surfaces. B, Biointerfaces, 2022, Volume: 215

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; Exo

2022
Tumor-derived exosomes reversing TMZ resistance by synergistic drug delivery for glioma-targeting treatment.
    Colloids and surfaces. B, Biointerfaces, 2022, Volume: 215

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; Exo

2022
A retrospective observational study on cases of anaplastic brain tumors treated with the Di Bella Method: A rationale and effectiveness.
    Neuro endocrinology letters, 2021, Nov-30, Volume: 42, Issue:7

    Topics: Acetazolamide; Antioxidants; Brain Neoplasms; Ditiocarb; Glioblastoma; Humans; Hydroxyurea; Melatoni

2021
A retrospective observational study on cases of anaplastic brain tumors treated with the Di Bella Method: A rationale and effectiveness.
    Neuro endocrinology letters, 2021, Nov-30, Volume: 42, Issue:7

    Topics: Acetazolamide; Antioxidants; Brain Neoplasms; Ditiocarb; Glioblastoma; Humans; Hydroxyurea; Melatoni

2021
A retrospective observational study on cases of anaplastic brain tumors treated with the Di Bella Method: A rationale and effectiveness.
    Neuro endocrinology letters, 2021, Nov-30, Volume: 42, Issue:7

    Topics: Acetazolamide; Antioxidants; Brain Neoplasms; Ditiocarb; Glioblastoma; Humans; Hydroxyurea; Melatoni

2021
Mannose inhibits proliferation and promotes apoptosis to enhance sensitivity of glioma cells to temozolomide through Wnt/β-catenin signaling pathway.
    Neurochemistry international, 2022, Volume: 157

    Topics: Apoptosis; beta Catenin; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Drug Resistance, Neo

2022
Mannose inhibits proliferation and promotes apoptosis to enhance sensitivity of glioma cells to temozolomide through Wnt/β-catenin signaling pathway.
    Neurochemistry international, 2022, Volume: 157

    Topics: Apoptosis; beta Catenin; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Drug Resistance, Neo

2022
Mannose inhibits proliferation and promotes apoptosis to enhance sensitivity of glioma cells to temozolomide through Wnt/β-catenin signaling pathway.
    Neurochemistry international, 2022, Volume: 157

    Topics: Apoptosis; beta Catenin; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Drug Resistance, Neo

2022
Salvianolic acid A (Sal A) suppresses malignant progression of glioma and enhances temozolomide (TMZ) sensitivity via repressing transgelin-2 (TAGLN2) mediated phosphatidylinositol-3-kinase (PI3K) / protein kinase B (Akt) pathway.
    Bioengineered, 2022, Volume: 13, Issue:5

    Topics: Brain Neoplasms; Caffeic Acids; Cell Line, Tumor; Glioma; Humans; Lactates; Microfilament Proteins;

2022
Salvianolic acid A (Sal A) suppresses malignant progression of glioma and enhances temozolomide (TMZ) sensitivity via repressing transgelin-2 (TAGLN2) mediated phosphatidylinositol-3-kinase (PI3K) / protein kinase B (Akt) pathway.
    Bioengineered, 2022, Volume: 13, Issue:5

    Topics: Brain Neoplasms; Caffeic Acids; Cell Line, Tumor; Glioma; Humans; Lactates; Microfilament Proteins;

2022
Salvianolic acid A (Sal A) suppresses malignant progression of glioma and enhances temozolomide (TMZ) sensitivity via repressing transgelin-2 (TAGLN2) mediated phosphatidylinositol-3-kinase (PI3K) / protein kinase B (Akt) pathway.
    Bioengineered, 2022, Volume: 13, Issue:5

    Topics: Brain Neoplasms; Caffeic Acids; Cell Line, Tumor; Glioma; Humans; Lactates; Microfilament Proteins;

2022
Characteristics of Anaplastic Oligodendrogliomas Short-Term Survivors: A POLA Network Study.
    The oncologist, 2022, 05-06, Volume: 27, Issue:5

    Topics: Brain Neoplasms; Chromosome Aberrations; Humans; Oligodendroglioma; Retrospective Studies; Survivors

2022
Characteristics of Anaplastic Oligodendrogliomas Short-Term Survivors: A POLA Network Study.
    The oncologist, 2022, 05-06, Volume: 27, Issue:5

    Topics: Brain Neoplasms; Chromosome Aberrations; Humans; Oligodendroglioma; Retrospective Studies; Survivors

2022
Characteristics of Anaplastic Oligodendrogliomas Short-Term Survivors: A POLA Network Study.
    The oncologist, 2022, 05-06, Volume: 27, Issue:5

    Topics: Brain Neoplasms; Chromosome Aberrations; Humans; Oligodendroglioma; Retrospective Studies; Survivors

2022
Integration of synthetic and natural derivatives revives the therapeutic potential of temozolomide against glioma- an in vitro and in vivo perspective.
    Life sciences, 2022, Jul-15, Volume: 301

    Topics: Animals; Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Glioma; HE

2022
Integration of synthetic and natural derivatives revives the therapeutic potential of temozolomide against glioma- an in vitro and in vivo perspective.
    Life sciences, 2022, Jul-15, Volume: 301

    Topics: Animals; Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Glioma; HE

2022
Integration of synthetic and natural derivatives revives the therapeutic potential of temozolomide against glioma- an in vitro and in vivo perspective.
    Life sciences, 2022, Jul-15, Volume: 301

    Topics: Animals; Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Glioma; HE

2022
Cyanidin-3-O-glucoside inhibits the β-catenin/MGMT pathway by upregulating miR-214-5p to reverse chemotherapy resistance in glioma cells.
    Scientific reports, 2022, 05-11, Volume: 12, Issue:1

    Topics: Anthocyanins; Antineoplastic Agents, Alkylating; Apoptosis; beta Catenin; Brain Neoplasms; Cell Line

2022
Cyanidin-3-O-glucoside inhibits the β-catenin/MGMT pathway by upregulating miR-214-5p to reverse chemotherapy resistance in glioma cells.
    Scientific reports, 2022, 05-11, Volume: 12, Issue:1

    Topics: Anthocyanins; Antineoplastic Agents, Alkylating; Apoptosis; beta Catenin; Brain Neoplasms; Cell Line

2022
Cyanidin-3-O-glucoside inhibits the β-catenin/MGMT pathway by upregulating miR-214-5p to reverse chemotherapy resistance in glioma cells.
    Scientific reports, 2022, 05-11, Volume: 12, Issue:1

    Topics: Anthocyanins; Antineoplastic Agents, Alkylating; Apoptosis; beta Catenin; Brain Neoplasms; Cell Line

2022
Effects of Long-Term Temozolomide Treatment on Glioblastoma and Astrocytoma WHO Grade 4 Stem-like Cells.
    International journal of molecular sciences, 2022, May-07, Volume: 23, Issue:9

    Topics: Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neoplasms; DNA Methylation; DNA Modification M

2022
Effects of Long-Term Temozolomide Treatment on Glioblastoma and Astrocytoma WHO Grade 4 Stem-like Cells.
    International journal of molecular sciences, 2022, May-07, Volume: 23, Issue:9

    Topics: Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neoplasms; DNA Methylation; DNA Modification M

2022
Effects of Long-Term Temozolomide Treatment on Glioblastoma and Astrocytoma WHO Grade 4 Stem-like Cells.
    International journal of molecular sciences, 2022, May-07, Volume: 23, Issue:9

    Topics: Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neoplasms; DNA Methylation; DNA Modification M

2022
Investigating the Stability of Six Phenolic TMZ Ester Analogues, Incubated in the Presence of Porcine Liver Esterase and Monitored by HPLC.
    Molecules (Basel, Switzerland), 2022, May-05, Volume: 27, Issue:9

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Chromatography, High

2022
Investigating the Stability of Six Phenolic TMZ Ester Analogues, Incubated in the Presence of Porcine Liver Esterase and Monitored by HPLC.
    Molecules (Basel, Switzerland), 2022, May-05, Volume: 27, Issue:9

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Chromatography, High

2022
Investigating the Stability of Six Phenolic TMZ Ester Analogues, Incubated in the Presence of Porcine Liver Esterase and Monitored by HPLC.
    Molecules (Basel, Switzerland), 2022, May-05, Volume: 27, Issue:9

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Chromatography, High

2022
[Glioblastoma That Does Not Improve with Standard Treatment: Poor Prognostic Factors and Future Perspectives].
    Brain and nerve = Shinkei kenkyu no shinpo, 2022, Volume: 74, Issue:5

    Topics: Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; DNA Methylation; Glioblastoma; Humans; Pro

2022
[Glioblastoma That Does Not Improve with Standard Treatment: Poor Prognostic Factors and Future Perspectives].
    Brain and nerve = Shinkei kenkyu no shinpo, 2022, Volume: 74, Issue:5

    Topics: Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; DNA Methylation; Glioblastoma; Humans; Pro

2022
[Glioblastoma That Does Not Improve with Standard Treatment: Poor Prognostic Factors and Future Perspectives].
    Brain and nerve = Shinkei kenkyu no shinpo, 2022, Volume: 74, Issue:5

    Topics: Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; DNA Methylation; Glioblastoma; Humans; Pro

2022
[Glioblastoma That Does Not Improve with Standard Treatment: Standard and Personalized Treatment Making The Most of Limited Modalities].
    Brain and nerve = Shinkei kenkyu no shinpo, 2022, Volume: 74, Issue:5

    Topics: Brain Neoplasms; Carmustine; Combined Modality Therapy; Glioblastoma; Humans; Precision Medicine; Te

2022
[Glioblastoma That Does Not Improve with Standard Treatment: Standard and Personalized Treatment Making The Most of Limited Modalities].
    Brain and nerve = Shinkei kenkyu no shinpo, 2022, Volume: 74, Issue:5

    Topics: Brain Neoplasms; Carmustine; Combined Modality Therapy; Glioblastoma; Humans; Precision Medicine; Te

2022
[Glioblastoma That Does Not Improve with Standard Treatment: Standard and Personalized Treatment Making The Most of Limited Modalities].
    Brain and nerve = Shinkei kenkyu no shinpo, 2022, Volume: 74, Issue:5

    Topics: Brain Neoplasms; Carmustine; Combined Modality Therapy; Glioblastoma; Humans; Precision Medicine; Te

2022
Preliminary Study on Relationship Between Temozolomide Chemotherapy-Resistant Cells and Stem Cells in Gliomas.
    Turkish neurosurgery, 2022, Volume: 32, Issue:3

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; Gli

2022
Preliminary Study on Relationship Between Temozolomide Chemotherapy-Resistant Cells and Stem Cells in Gliomas.
    Turkish neurosurgery, 2022, Volume: 32, Issue:3

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; Gli

2022
Preliminary Study on Relationship Between Temozolomide Chemotherapy-Resistant Cells and Stem Cells in Gliomas.
    Turkish neurosurgery, 2022, Volume: 32, Issue:3

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; Gli

2022
Single-cell RNA sequencing reveals evolution of immune landscape during glioblastoma progression.
    Nature immunology, 2022, Volume: 23, Issue:6

    Topics: Animals; Brain Neoplasms; ErbB Receptors; Glioblastoma; Glioma; Humans; Mice; Sequence Analysis, RNA

2022
Single-cell RNA sequencing reveals evolution of immune landscape during glioblastoma progression.
    Nature immunology, 2022, Volume: 23, Issue:6

    Topics: Animals; Brain Neoplasms; ErbB Receptors; Glioblastoma; Glioma; Humans; Mice; Sequence Analysis, RNA

2022
Single-cell RNA sequencing reveals evolution of immune landscape during glioblastoma progression.
    Nature immunology, 2022, Volume: 23, Issue:6

    Topics: Animals; Brain Neoplasms; ErbB Receptors; Glioblastoma; Glioma; Humans; Mice; Sequence Analysis, RNA

2022
lncRNA XLOC013218 promotes cell proliferation and TMZ resistance by targeting the PIK3R2-mediated PI3K/AKT pathway in glioma.
    Cancer science, 2022, Volume: 113, Issue:8

    Topics: Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Drug Resistance, Neoplasm; Gene Expression Re

2022
lncRNA XLOC013218 promotes cell proliferation and TMZ resistance by targeting the PIK3R2-mediated PI3K/AKT pathway in glioma.
    Cancer science, 2022, Volume: 113, Issue:8

    Topics: Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Drug Resistance, Neoplasm; Gene Expression Re

2022
lncRNA XLOC013218 promotes cell proliferation and TMZ resistance by targeting the PIK3R2-mediated PI3K/AKT pathway in glioma.
    Cancer science, 2022, Volume: 113, Issue:8

    Topics: Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Drug Resistance, Neoplasm; Gene Expression Re

2022
Glioblastoma spheroid growth and chemotherapeutic responses in single and dual-stiffness hydrogels.
    Acta biomaterialia, 2023, Volume: 163

    Topics: Brain; Brain Neoplasms; Cell Line, Tumor; Glioblastoma; Humans; Hydrogels; Laminin; Spheroids, Cellu

2023
Glioblastoma spheroid growth and chemotherapeutic responses in single and dual-stiffness hydrogels.
    Acta biomaterialia, 2023, Volume: 163

    Topics: Brain; Brain Neoplasms; Cell Line, Tumor; Glioblastoma; Humans; Hydrogels; Laminin; Spheroids, Cellu

2023
Glioblastoma spheroid growth and chemotherapeutic responses in single and dual-stiffness hydrogels.
    Acta biomaterialia, 2023, Volume: 163

    Topics: Brain; Brain Neoplasms; Cell Line, Tumor; Glioblastoma; Humans; Hydrogels; Laminin; Spheroids, Cellu

2023
MGMT in glial carcinogenesis. Roles from prevention to treatment.
    European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP), 2022, 11-01, Volume: 31, Issue:6

    Topics: Brain Neoplasms; Carcinogenesis; Carcinogens; Dacarbazine; DNA; DNA Methylation; DNA Modification Me

2022
MGMT in glial carcinogenesis. Roles from prevention to treatment.
    European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP), 2022, 11-01, Volume: 31, Issue:6

    Topics: Brain Neoplasms; Carcinogenesis; Carcinogens; Dacarbazine; DNA; DNA Methylation; DNA Modification Me

2022
MGMT in glial carcinogenesis. Roles from prevention to treatment.
    European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP), 2022, 11-01, Volume: 31, Issue:6

    Topics: Brain Neoplasms; Carcinogenesis; Carcinogens; Dacarbazine; DNA; DNA Methylation; DNA Modification Me

2022
PTRF/Cavin-1 enhances chemo-resistance and promotes temozolomide efflux through extracellular vesicles in glioblastoma.
    Theranostics, 2022, Volume: 12, Issue:9

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; Ext

2022
PTRF/Cavin-1 enhances chemo-resistance and promotes temozolomide efflux through extracellular vesicles in glioblastoma.
    Theranostics, 2022, Volume: 12, Issue:9

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; Ext

2022
PTRF/Cavin-1 enhances chemo-resistance and promotes temozolomide efflux through extracellular vesicles in glioblastoma.
    Theranostics, 2022, Volume: 12, Issue:9

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; Ext

2022
Inhibition of Ciliogenesis Enhances the Cellular Sensitivity to Temozolomide and Ionizing Radiation in Human Glioblastoma Cells.
    Biomedical and environmental sciences : BES, 2022, May-20, Volume: 35, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; DNA; Glioblastoma; Humans; Rad

2022
Inhibition of Ciliogenesis Enhances the Cellular Sensitivity to Temozolomide and Ionizing Radiation in Human Glioblastoma Cells.
    Biomedical and environmental sciences : BES, 2022, May-20, Volume: 35, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; DNA; Glioblastoma; Humans; Rad

2022
Inhibition of Ciliogenesis Enhances the Cellular Sensitivity to Temozolomide and Ionizing Radiation in Human Glioblastoma Cells.
    Biomedical and environmental sciences : BES, 2022, May-20, Volume: 35, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; DNA; Glioblastoma; Humans; Rad

2022
Association of plasma levetiracetam concentration, MGMT methylation and sex with survival of chemoradiotherapy-treated glioblastoma patients.
    Pharmacological research, 2022, Volume: 181

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Dacarbazine; DNA

2022
Association of plasma levetiracetam concentration, MGMT methylation and sex with survival of chemoradiotherapy-treated glioblastoma patients.
    Pharmacological research, 2022, Volume: 181

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Dacarbazine; DNA

2022
Association of plasma levetiracetam concentration, MGMT methylation and sex with survival of chemoradiotherapy-treated glioblastoma patients.
    Pharmacological research, 2022, Volume: 181

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Dacarbazine; DNA

2022
Targeted liposomes for combined delivery of artesunate and temozolomide to resistant glioblastoma.
    Biomaterials, 2022, Volume: 287

    Topics: Animals; Antineoplastic Agents, Alkylating; Apolipoproteins E; Artesunate; Brain Neoplasms; Cell Lin

2022
Targeted liposomes for combined delivery of artesunate and temozolomide to resistant glioblastoma.
    Biomaterials, 2022, Volume: 287

    Topics: Animals; Antineoplastic Agents, Alkylating; Apolipoproteins E; Artesunate; Brain Neoplasms; Cell Lin

2022
Targeted liposomes for combined delivery of artesunate and temozolomide to resistant glioblastoma.
    Biomaterials, 2022, Volume: 287

    Topics: Animals; Antineoplastic Agents, Alkylating; Apolipoproteins E; Artesunate; Brain Neoplasms; Cell Lin

2022
FOXM1-mediated NUF2 expression confers temozolomide resistance to human glioma cells by regulating autophagy via the PI3K/AKT/mTOR signaling pathway.
    Neuropathology : official journal of the Japanese Society of Neuropathology, 2022, Volume: 42, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Apoptosis; Autophagy; Brain Neoplasms; Cell Cycle Proteins; Cell

2022
FOXM1-mediated NUF2 expression confers temozolomide resistance to human glioma cells by regulating autophagy via the PI3K/AKT/mTOR signaling pathway.
    Neuropathology : official journal of the Japanese Society of Neuropathology, 2022, Volume: 42, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Apoptosis; Autophagy; Brain Neoplasms; Cell Cycle Proteins; Cell

2022
FOXM1-mediated NUF2 expression confers temozolomide resistance to human glioma cells by regulating autophagy via the PI3K/AKT/mTOR signaling pathway.
    Neuropathology : official journal of the Japanese Society of Neuropathology, 2022, Volume: 42, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Apoptosis; Autophagy; Brain Neoplasms; Cell Cycle Proteins; Cell

2022
Diazepam diminishes temozolomide efficacy in the treatment of U87 glioblastoma cell line.
    CNS neuroscience & therapeutics, 2022, Volume: 28, Issue:9

    Topics: Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation;

2022
Diazepam diminishes temozolomide efficacy in the treatment of U87 glioblastoma cell line.
    CNS neuroscience & therapeutics, 2022, Volume: 28, Issue:9

    Topics: Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation;

2022
Diazepam diminishes temozolomide efficacy in the treatment of U87 glioblastoma cell line.
    CNS neuroscience & therapeutics, 2022, Volume: 28, Issue:9

    Topics: Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation;

2022
Selective cell cycle arrest in glioblastoma cell lines by quantum molecular resonance alone or in combination with temozolomide.
    British journal of cancer, 2022, Volume: 127, Issue:5

    Topics: Brain Neoplasms; Cell Cycle Checkpoints; Cell Line; Cell Line, Tumor; Glioblastoma; Humans; Proteomi

2022
Selective cell cycle arrest in glioblastoma cell lines by quantum molecular resonance alone or in combination with temozolomide.
    British journal of cancer, 2022, Volume: 127, Issue:5

    Topics: Brain Neoplasms; Cell Cycle Checkpoints; Cell Line; Cell Line, Tumor; Glioblastoma; Humans; Proteomi

2022
Selective cell cycle arrest in glioblastoma cell lines by quantum molecular resonance alone or in combination with temozolomide.
    British journal of cancer, 2022, Volume: 127, Issue:5

    Topics: Brain Neoplasms; Cell Cycle Checkpoints; Cell Line; Cell Line, Tumor; Glioblastoma; Humans; Proteomi

2022
SOCS5 contributes to temozolomide resistance in glioblastoma by regulating Bcl-2-mediated autophagy.
    Bioengineered, 2022, Volume: 13, Issue:6

    Topics: Autophagy; Brain Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; Glioblastoma; Humans; Suppr

2022
SOCS5 contributes to temozolomide resistance in glioblastoma by regulating Bcl-2-mediated autophagy.
    Bioengineered, 2022, Volume: 13, Issue:6

    Topics: Autophagy; Brain Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; Glioblastoma; Humans; Suppr

2022
SOCS5 contributes to temozolomide resistance in glioblastoma by regulating Bcl-2-mediated autophagy.
    Bioengineered, 2022, Volume: 13, Issue:6

    Topics: Autophagy; Brain Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; Glioblastoma; Humans; Suppr

2022
Targeting CXCR4 to suppress glioma-initiating cells and chemoresistance in glioma.
    Cell biology international, 2022, Volume: 46, Issue:9

    Topics: Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Drug Resistance, Neoplasm; Glioma; Humans; Mu

2022
Targeting CXCR4 to suppress glioma-initiating cells and chemoresistance in glioma.
    Cell biology international, 2022, Volume: 46, Issue:9

    Topics: Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Drug Resistance, Neoplasm; Glioma; Humans; Mu

2022
Targeting CXCR4 to suppress glioma-initiating cells and chemoresistance in glioma.
    Cell biology international, 2022, Volume: 46, Issue:9

    Topics: Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Drug Resistance, Neoplasm; Glioma; Humans; Mu

2022
Temozolomide-induced guanine mutations create exploitable vulnerabilities of guanine-rich DNA and RNA regions in drug-resistant gliomas.
    Science advances, 2022, 06-24, Volume: 8, Issue:25

    Topics: Antineoplastic Agents; Brain Neoplasms; Cell Line, Tumor; DNA; Drug Resistance, Neoplasm; Glioblasto

2022
Temozolomide-induced guanine mutations create exploitable vulnerabilities of guanine-rich DNA and RNA regions in drug-resistant gliomas.
    Science advances, 2022, 06-24, Volume: 8, Issue:25

    Topics: Antineoplastic Agents; Brain Neoplasms; Cell Line, Tumor; DNA; Drug Resistance, Neoplasm; Glioblasto

2022
Temozolomide-induced guanine mutations create exploitable vulnerabilities of guanine-rich DNA and RNA regions in drug-resistant gliomas.
    Science advances, 2022, 06-24, Volume: 8, Issue:25

    Topics: Antineoplastic Agents; Brain Neoplasms; Cell Line, Tumor; DNA; Drug Resistance, Neoplasm; Glioblasto

2022
Brain Co-Delivery of Temozolomide and Cisplatin for Combinatorial Glioblastoma Chemotherapy.
    Advanced materials (Deerfield Beach, Fla.), 2022, Volume: 34, Issue:33

    Topics: Animals; Blood-Brain Barrier; Brain Neoplasms; Cell Line, Tumor; Cisplatin; Drug Resistance, Neoplas

2022
Brain Co-Delivery of Temozolomide and Cisplatin for Combinatorial Glioblastoma Chemotherapy.
    Advanced materials (Deerfield Beach, Fla.), 2022, Volume: 34, Issue:33

    Topics: Animals; Blood-Brain Barrier; Brain Neoplasms; Cell Line, Tumor; Cisplatin; Drug Resistance, Neoplas

2022
Brain Co-Delivery of Temozolomide and Cisplatin for Combinatorial Glioblastoma Chemotherapy.
    Advanced materials (Deerfield Beach, Fla.), 2022, Volume: 34, Issue:33

    Topics: Animals; Blood-Brain Barrier; Brain Neoplasms; Cell Line, Tumor; Cisplatin; Drug Resistance, Neoplas

2022
Temozolomide increases heat shock proteins in extracellular vesicles released from glioblastoma cells.
    Molecular biology reports, 2022, Volume: 49, Issue:9

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; Ext

2022
Temozolomide increases heat shock proteins in extracellular vesicles released from glioblastoma cells.
    Molecular biology reports, 2022, Volume: 49, Issue:9

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; Ext

2022
Temozolomide increases heat shock proteins in extracellular vesicles released from glioblastoma cells.
    Molecular biology reports, 2022, Volume: 49, Issue:9

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; Ext

2022
The role of Shikonin in improving 5-aminolevulinic acid-based photodynamic therapy and chemotherapy on glioblastoma stem cells.
    Photodiagnosis and photodynamic therapy, 2022, Volume: 39

    Topics: Aminolevulinic Acid; Brain Neoplasms; Cell Line, Tumor; Glioblastoma; Humans; Naphthoquinones; Neopl

2022
The role of Shikonin in improving 5-aminolevulinic acid-based photodynamic therapy and chemotherapy on glioblastoma stem cells.
    Photodiagnosis and photodynamic therapy, 2022, Volume: 39

    Topics: Aminolevulinic Acid; Brain Neoplasms; Cell Line, Tumor; Glioblastoma; Humans; Naphthoquinones; Neopl

2022
The role of Shikonin in improving 5-aminolevulinic acid-based photodynamic therapy and chemotherapy on glioblastoma stem cells.
    Photodiagnosis and photodynamic therapy, 2022, Volume: 39

    Topics: Aminolevulinic Acid; Brain Neoplasms; Cell Line, Tumor; Glioblastoma; Humans; Naphthoquinones; Neopl

2022
GBP3 promotes glioblastoma resistance to temozolomide by enhancing DNA damage repair.
    Oncogene, 2022, Volume: 41, Issue:31

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; DNA Damage; DNA Modif

2022
GBP3 promotes glioblastoma resistance to temozolomide by enhancing DNA damage repair.
    Oncogene, 2022, Volume: 41, Issue:31

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; DNA Damage; DNA Modif

2022
GBP3 promotes glioblastoma resistance to temozolomide by enhancing DNA damage repair.
    Oncogene, 2022, Volume: 41, Issue:31

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; DNA Damage; DNA Modif

2022
Propofol enhances the sensitivity of glioblastoma cells to temozolomide by inhibiting macrophage activation in tumor microenvironment to down-regulate HIF-1α expression.
    Experimental cell research, 2022, 09-15, Volume: 418, Issue:2

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Cyclooxygenase 2; Dru

2022
Propofol enhances the sensitivity of glioblastoma cells to temozolomide by inhibiting macrophage activation in tumor microenvironment to down-regulate HIF-1α expression.
    Experimental cell research, 2022, 09-15, Volume: 418, Issue:2

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Cyclooxygenase 2; Dru

2022
Propofol enhances the sensitivity of glioblastoma cells to temozolomide by inhibiting macrophage activation in tumor microenvironment to down-regulate HIF-1α expression.
    Experimental cell research, 2022, 09-15, Volume: 418, Issue:2

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Cyclooxygenase 2; Dru

2022
Exosomal circWDR62 promotes temozolomide resistance and malignant progression through regulation of the miR-370-3p/MGMT axis in glioma.
    Cell death & disease, 2022, 07-11, Volume: 13, Issue:7

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; DNA Modifi

2022
Exosomal circWDR62 promotes temozolomide resistance and malignant progression through regulation of the miR-370-3p/MGMT axis in glioma.
    Cell death & disease, 2022, 07-11, Volume: 13, Issue:7

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; DNA Modifi

2022
Exosomal circWDR62 promotes temozolomide resistance and malignant progression through regulation of the miR-370-3p/MGMT axis in glioma.
    Cell death & disease, 2022, 07-11, Volume: 13, Issue:7

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; DNA Modifi

2022
SH3GLB1-related autophagy mediates mitochondrial metabolism to acquire resistance against temozolomide in glioblastoma.
    Journal of experimental & clinical cancer research : CR, 2022, Jul-13, Volume: 41, Issue:1

    Topics: Animals; Antineoplastic Agents, Alkylating; Autophagy; Brain Neoplasms; Cell Line, Tumor; Drug Resis

2022
SH3GLB1-related autophagy mediates mitochondrial metabolism to acquire resistance against temozolomide in glioblastoma.
    Journal of experimental & clinical cancer research : CR, 2022, Jul-13, Volume: 41, Issue:1

    Topics: Animals; Antineoplastic Agents, Alkylating; Autophagy; Brain Neoplasms; Cell Line, Tumor; Drug Resis

2022
SH3GLB1-related autophagy mediates mitochondrial metabolism to acquire resistance against temozolomide in glioblastoma.
    Journal of experimental & clinical cancer research : CR, 2022, Jul-13, Volume: 41, Issue:1

    Topics: Animals; Antineoplastic Agents, Alkylating; Autophagy; Brain Neoplasms; Cell Line, Tumor; Drug Resis

2022
Dual-sensitive drug-loaded hydrogel system for local inhibition of post-surgical glioma recurrence.
    Journal of controlled release : official journal of the Controlled Release Society, 2022, Volume: 349

    Topics: Brain Neoplasms; Carmustine; Cell Line, Tumor; Glioma; Humans; Hydrogels; Neoplasm Recurrence, Local

2022
Dual-sensitive drug-loaded hydrogel system for local inhibition of post-surgical glioma recurrence.
    Journal of controlled release : official journal of the Controlled Release Society, 2022, Volume: 349

    Topics: Brain Neoplasms; Carmustine; Cell Line, Tumor; Glioma; Humans; Hydrogels; Neoplasm Recurrence, Local

2022
Dual-sensitive drug-loaded hydrogel system for local inhibition of post-surgical glioma recurrence.
    Journal of controlled release : official journal of the Controlled Release Society, 2022, Volume: 349

    Topics: Brain Neoplasms; Carmustine; Cell Line, Tumor; Glioma; Humans; Hydrogels; Neoplasm Recurrence, Local

2022
A rationally identified panel of microRNAs targets multiple oncogenic pathways to enhance chemotherapeutic effects in glioblastoma models.
    Scientific reports, 2022, 07-14, Volume: 12, Issue:1

    Topics: Animals; Brain Neoplasms; Carcinogenesis; Cell Line, Tumor; Drug Resistance, Neoplasm; Gene Expressi

2022
A rationally identified panel of microRNAs targets multiple oncogenic pathways to enhance chemotherapeutic effects in glioblastoma models.
    Scientific reports, 2022, 07-14, Volume: 12, Issue:1

    Topics: Animals; Brain Neoplasms; Carcinogenesis; Cell Line, Tumor; Drug Resistance, Neoplasm; Gene Expressi

2022
A rationally identified panel of microRNAs targets multiple oncogenic pathways to enhance chemotherapeutic effects in glioblastoma models.
    Scientific reports, 2022, 07-14, Volume: 12, Issue:1

    Topics: Animals; Brain Neoplasms; Carcinogenesis; Cell Line, Tumor; Drug Resistance, Neoplasm; Gene Expressi

2022
PDIA3P1 promotes Temozolomide resistance in glioblastoma by inhibiting C/EBPβ degradation to facilitate proneural-to-mesenchymal transition.
    Journal of experimental & clinical cancer research : CR, 2022, Jul-15, Volume: 41, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; Gen

2022
PDIA3P1 promotes Temozolomide resistance in glioblastoma by inhibiting C/EBPβ degradation to facilitate proneural-to-mesenchymal transition.
    Journal of experimental & clinical cancer research : CR, 2022, Jul-15, Volume: 41, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; Gen

2022
PDIA3P1 promotes Temozolomide resistance in glioblastoma by inhibiting C/EBPβ degradation to facilitate proneural-to-mesenchymal transition.
    Journal of experimental & clinical cancer research : CR, 2022, Jul-15, Volume: 41, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; Gen

2022
The trial effect in patients with glioblastoma: effect of clinical trial enrollment on overall survival.
    Journal of neuro-oncology, 2022, Volume: 159, Issue:2

    Topics: Brain Neoplasms; Clinical Trials as Topic; Cohort Studies; Glioblastoma; Humans; Prognosis; Temozolo

2022
The trial effect in patients with glioblastoma: effect of clinical trial enrollment on overall survival.
    Journal of neuro-oncology, 2022, Volume: 159, Issue:2

    Topics: Brain Neoplasms; Clinical Trials as Topic; Cohort Studies; Glioblastoma; Humans; Prognosis; Temozolo

2022
The trial effect in patients with glioblastoma: effect of clinical trial enrollment on overall survival.
    Journal of neuro-oncology, 2022, Volume: 159, Issue:2

    Topics: Brain Neoplasms; Clinical Trials as Topic; Cohort Studies; Glioblastoma; Humans; Prognosis; Temozolo

2022
TTK Protein Kinase promotes temozolomide resistance through inducing autophagy in glioblastoma.
    BMC cancer, 2022, Jul-18, Volume: 22, Issue:1

    Topics: Animals; Antineoplastic Agents, Alkylating; Autophagy; Brain Neoplasms; Cell Cycle Proteins; Cell Li

2022
TTK Protein Kinase promotes temozolomide resistance through inducing autophagy in glioblastoma.
    BMC cancer, 2022, Jul-18, Volume: 22, Issue:1

    Topics: Animals; Antineoplastic Agents, Alkylating; Autophagy; Brain Neoplasms; Cell Cycle Proteins; Cell Li

2022
TTK Protein Kinase promotes temozolomide resistance through inducing autophagy in glioblastoma.
    BMC cancer, 2022, Jul-18, Volume: 22, Issue:1

    Topics: Animals; Antineoplastic Agents, Alkylating; Autophagy; Brain Neoplasms; Cell Cycle Proteins; Cell Li

2022
Continuing maintenance temozolomide therapy beyond 12 cycles confers no clinical benefit over discontinuation at 12 cycles in patients with IDH1/2-wildtype glioblastoma.
    Japanese journal of clinical oncology, 2022, Oct-06, Volume: 52, Issue:10

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Disease Progression; Disease-Free S

2022
Continuing maintenance temozolomide therapy beyond 12 cycles confers no clinical benefit over discontinuation at 12 cycles in patients with IDH1/2-wildtype glioblastoma.
    Japanese journal of clinical oncology, 2022, Oct-06, Volume: 52, Issue:10

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Disease Progression; Disease-Free S

2022
Continuing maintenance temozolomide therapy beyond 12 cycles confers no clinical benefit over discontinuation at 12 cycles in patients with IDH1/2-wildtype glioblastoma.
    Japanese journal of clinical oncology, 2022, Oct-06, Volume: 52, Issue:10

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Disease Progression; Disease-Free S

2022
ZSTK474 Sensitizes Glioblastoma to Temozolomide by Blocking Homologous Recombination Repair.
    BioMed research international, 2022, Volume: 2022

    Topics: Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cell Line, Tumor; DNA Repair; Drug Re

2022
ZSTK474 Sensitizes Glioblastoma to Temozolomide by Blocking Homologous Recombination Repair.
    BioMed research international, 2022, Volume: 2022

    Topics: Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cell Line, Tumor; DNA Repair; Drug Re

2022
ZSTK474 Sensitizes Glioblastoma to Temozolomide by Blocking Homologous Recombination Repair.
    BioMed research international, 2022, Volume: 2022

    Topics: Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cell Line, Tumor; DNA Repair; Drug Re

2022
TRAF4 Maintains Deubiquitination of Caveolin-1 to Drive Glioblastoma Stemness and Temozolomide Resistance.
    Cancer research, 2022, Oct-04, Volume: 82, Issue:19

    Topics: Brain Neoplasms; Caveolin 1; Cell Line, Tumor; Drug Resistance, Neoplasm; Glioblastoma; Humans; Neop

2022
TRAF4 Maintains Deubiquitination of Caveolin-1 to Drive Glioblastoma Stemness and Temozolomide Resistance.
    Cancer research, 2022, Oct-04, Volume: 82, Issue:19

    Topics: Brain Neoplasms; Caveolin 1; Cell Line, Tumor; Drug Resistance, Neoplasm; Glioblastoma; Humans; Neop

2022
TRAF4 Maintains Deubiquitination of Caveolin-1 to Drive Glioblastoma Stemness and Temozolomide Resistance.
    Cancer research, 2022, Oct-04, Volume: 82, Issue:19

    Topics: Brain Neoplasms; Caveolin 1; Cell Line, Tumor; Drug Resistance, Neoplasm; Glioblastoma; Humans; Neop

2022
Exploring the Mechanism of Adjuvant Treatment of Glioblastoma Using Temozolomide and Metformin.
    International journal of molecular sciences, 2022, Jul-25, Volume: 23, Issue:15

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Diabetes Mellitus, Type 2; DNA

2022
Exploring the Mechanism of Adjuvant Treatment of Glioblastoma Using Temozolomide and Metformin.
    International journal of molecular sciences, 2022, Jul-25, Volume: 23, Issue:15

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Diabetes Mellitus, Type 2; DNA

2022
Exploring the Mechanism of Adjuvant Treatment of Glioblastoma Using Temozolomide and Metformin.
    International journal of molecular sciences, 2022, Jul-25, Volume: 23, Issue:15

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Diabetes Mellitus, Type 2; DNA

2022
Mechanism-based design of agents that selectively target drug-resistant glioma.
    Science (New York, N.Y.), 2022, 07-29, Volume: 377, Issue:6605

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Dacarbazine; DNA Methylation;

2022
Mechanism-based design of agents that selectively target drug-resistant glioma.
    Science (New York, N.Y.), 2022, 07-29, Volume: 377, Issue:6605

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Dacarbazine; DNA Methylation;

2022
Mechanism-based design of agents that selectively target drug-resistant glioma.
    Science (New York, N.Y.), 2022, 07-29, Volume: 377, Issue:6605

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Dacarbazine; DNA Methylation;

2022
MIR99AHG/miR-204-5p/TXNIP/Nrf2/ARE Signaling Pathway Decreases Glioblastoma Temozolomide Sensitivity.
    Neurotoxicity research, 2022, Volume: 40, Issue:5

    Topics: Brain Neoplasms; Carrier Proteins; Cell Line, Tumor; Cell Proliferation; Gene Expression Regulation,

2022
MIR99AHG/miR-204-5p/TXNIP/Nrf2/ARE Signaling Pathway Decreases Glioblastoma Temozolomide Sensitivity.
    Neurotoxicity research, 2022, Volume: 40, Issue:5

    Topics: Brain Neoplasms; Carrier Proteins; Cell Line, Tumor; Cell Proliferation; Gene Expression Regulation,

2022
MIR99AHG/miR-204-5p/TXNIP/Nrf2/ARE Signaling Pathway Decreases Glioblastoma Temozolomide Sensitivity.
    Neurotoxicity research, 2022, Volume: 40, Issue:5

    Topics: Brain Neoplasms; Carrier Proteins; Cell Line, Tumor; Cell Proliferation; Gene Expression Regulation,

2022
ADAR3 activates NF-κB signaling and promotes glioblastoma cell resistance to temozolomide.
    Scientific reports, 2022, 08-03, Volume: 12, Issue:1

    Topics: Adenosine Deaminase; Brain Neoplasms; Cell Line, Tumor; Glioblastoma; Humans; NF-kappa B; RNA-Bindin

2022
ADAR3 activates NF-κB signaling and promotes glioblastoma cell resistance to temozolomide.
    Scientific reports, 2022, 08-03, Volume: 12, Issue:1

    Topics: Adenosine Deaminase; Brain Neoplasms; Cell Line, Tumor; Glioblastoma; Humans; NF-kappa B; RNA-Bindin

2022
ADAR3 activates NF-κB signaling and promotes glioblastoma cell resistance to temozolomide.
    Scientific reports, 2022, 08-03, Volume: 12, Issue:1

    Topics: Adenosine Deaminase; Brain Neoplasms; Cell Line, Tumor; Glioblastoma; Humans; NF-kappa B; RNA-Bindin

2022
Characterization and comparison of human glioblastoma models.
    BMC cancer, 2022, Aug-03, Volume: 22, Issue:1

    Topics: Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Glioblastoma; Humans; Temozolomide

2022
Characterization and comparison of human glioblastoma models.
    BMC cancer, 2022, Aug-03, Volume: 22, Issue:1

    Topics: Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Glioblastoma; Humans; Temozolomide

2022
Characterization and comparison of human glioblastoma models.
    BMC cancer, 2022, Aug-03, Volume: 22, Issue:1

    Topics: Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Glioblastoma; Humans; Temozolomide

2022
Substrate viscosity impairs temozolomide-mediated inhibition of glioblastoma cells' growth.
    Biochimica et biophysica acta. Molecular basis of disease, 2022, 11-01, Volume: 1868, Issue:11

    Topics: Antineoplastic Agents; Brain Neoplasms; Cell Proliferation; Glioblastoma; Glioma; Humans; Hydrogels;

2022
Substrate viscosity impairs temozolomide-mediated inhibition of glioblastoma cells' growth.
    Biochimica et biophysica acta. Molecular basis of disease, 2022, 11-01, Volume: 1868, Issue:11

    Topics: Antineoplastic Agents; Brain Neoplasms; Cell Proliferation; Glioblastoma; Glioma; Humans; Hydrogels;

2022
Substrate viscosity impairs temozolomide-mediated inhibition of glioblastoma cells' growth.
    Biochimica et biophysica acta. Molecular basis of disease, 2022, 11-01, Volume: 1868, Issue:11

    Topics: Antineoplastic Agents; Brain Neoplasms; Cell Proliferation; Glioblastoma; Glioma; Humans; Hydrogels;

2022
ZNF300 enhances temozolomide resistance in gliomas by regulating lncRNA SNHG12.
    General physiology and biophysics, 2022, Volume: 41, Issue:4

    Topics: Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Drug Resistance, Neoplasm; Gene Expression Re

2022
ZNF300 enhances temozolomide resistance in gliomas by regulating lncRNA SNHG12.
    General physiology and biophysics, 2022, Volume: 41, Issue:4

    Topics: Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Drug Resistance, Neoplasm; Gene Expression Re

2022
ZNF300 enhances temozolomide resistance in gliomas by regulating lncRNA SNHG12.
    General physiology and biophysics, 2022, Volume: 41, Issue:4

    Topics: Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Drug Resistance, Neoplasm; Gene Expression Re

2022
GMI, Ganoderma microsporum protein, suppresses cell mobility and increases temozolomide sensitivity through induction of Slug degradation in glioblastoma multiforme cells.
    International journal of biological macromolecules, 2022, Oct-31, Volume: 219

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Cell Movement; Drug Resistance

2022
GMI, Ganoderma microsporum protein, suppresses cell mobility and increases temozolomide sensitivity through induction of Slug degradation in glioblastoma multiforme cells.
    International journal of biological macromolecules, 2022, Oct-31, Volume: 219

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Cell Movement; Drug Resistance

2022
GMI, Ganoderma microsporum protein, suppresses cell mobility and increases temozolomide sensitivity through induction of Slug degradation in glioblastoma multiforme cells.
    International journal of biological macromolecules, 2022, Oct-31, Volume: 219

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Cell Movement; Drug Resistance

2022
Anticancer Effect of Cathelicidin LL-37, Protegrin PG-1, Nerve Growth Factor NGF, and Temozolomide: Impact on the Mitochondrial Metabolism, Clonogenic Potential, and Migration of Human U251 Glioma Cells.
    Molecules (Basel, Switzerland), 2022, Aug-05, Volume: 27, Issue:15

    Topics: Antimicrobial Cationic Peptides; Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cath

2022
Anticancer Effect of Cathelicidin LL-37, Protegrin PG-1, Nerve Growth Factor NGF, and Temozolomide: Impact on the Mitochondrial Metabolism, Clonogenic Potential, and Migration of Human U251 Glioma Cells.
    Molecules (Basel, Switzerland), 2022, Aug-05, Volume: 27, Issue:15

    Topics: Antimicrobial Cationic Peptides; Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cath

2022
Anticancer Effect of Cathelicidin LL-37, Protegrin PG-1, Nerve Growth Factor NGF, and Temozolomide: Impact on the Mitochondrial Metabolism, Clonogenic Potential, and Migration of Human U251 Glioma Cells.
    Molecules (Basel, Switzerland), 2022, Aug-05, Volume: 27, Issue:15

    Topics: Antimicrobial Cationic Peptides; Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cath

2022
Downregulated ferroptosis-related gene SQLE facilitates temozolomide chemoresistance, and invasion and affects immune regulation in glioblastoma.
    CNS neuroscience & therapeutics, 2022, Volume: 28, Issue:12

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; Fer

2022
Downregulated ferroptosis-related gene SQLE facilitates temozolomide chemoresistance, and invasion and affects immune regulation in glioblastoma.
    CNS neuroscience & therapeutics, 2022, Volume: 28, Issue:12

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; Fer

2022
Downregulated ferroptosis-related gene SQLE facilitates temozolomide chemoresistance, and invasion and affects immune regulation in glioblastoma.
    CNS neuroscience & therapeutics, 2022, Volume: 28, Issue:12

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; Fer

2022
Imaging Glioblastoma Response to Radiotherapy Using 2H Magnetic Resonance Spectroscopy Measurements of Fumarate Metabolism.
    Cancer research, 2022, Oct-04, Volume: 82, Issue:19

    Topics: Animals; Brain Neoplasms; Contrast Media; Fumarates; Glioblastoma; Humans; Magnetic Resonance Imagin

2022
Imaging Glioblastoma Response to Radiotherapy Using 2H Magnetic Resonance Spectroscopy Measurements of Fumarate Metabolism.
    Cancer research, 2022, Oct-04, Volume: 82, Issue:19

    Topics: Animals; Brain Neoplasms; Contrast Media; Fumarates; Glioblastoma; Humans; Magnetic Resonance Imagin

2022
Imaging Glioblastoma Response to Radiotherapy Using 2H Magnetic Resonance Spectroscopy Measurements of Fumarate Metabolism.
    Cancer research, 2022, Oct-04, Volume: 82, Issue:19

    Topics: Animals; Brain Neoplasms; Contrast Media; Fumarates; Glioblastoma; Humans; Magnetic Resonance Imagin

2022
Improved survival among females and association with lymphopenia in patients with newly diagnosed glioblastoma.
    Neuro-oncology, 2022, 11-02, Volume: 24, Issue:11

    Topics: Brain Neoplasms; Dacarbazine; Female; Glioblastoma; Humans; Lymphopenia; Temozolomide

2022
Improved survival among females and association with lymphopenia in patients with newly diagnosed glioblastoma.
    Neuro-oncology, 2022, 11-02, Volume: 24, Issue:11

    Topics: Brain Neoplasms; Dacarbazine; Female; Glioblastoma; Humans; Lymphopenia; Temozolomide

2022
Improved survival among females and association with lymphopenia in patients with newly diagnosed glioblastoma.
    Neuro-oncology, 2022, 11-02, Volume: 24, Issue:11

    Topics: Brain Neoplasms; Dacarbazine; Female; Glioblastoma; Humans; Lymphopenia; Temozolomide

2022
MicroRNA-640 Inhibition Enhances the Chemosensitivity of Human Glioblastoma Cells to Temozolomide by Targeting Bcl2 Modifying Factor.
    Biochemical genetics, 2023, Volume: 61, Issue:2

    Topics: Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Drug Resistance, Neoplasm; Gene Ex

2023
MicroRNA-640 Inhibition Enhances the Chemosensitivity of Human Glioblastoma Cells to Temozolomide by Targeting Bcl2 Modifying Factor.
    Biochemical genetics, 2023, Volume: 61, Issue:2

    Topics: Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Drug Resistance, Neoplasm; Gene Ex

2023
MicroRNA-640 Inhibition Enhances the Chemosensitivity of Human Glioblastoma Cells to Temozolomide by Targeting Bcl2 Modifying Factor.
    Biochemical genetics, 2023, Volume: 61, Issue:2

    Topics: Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Drug Resistance, Neoplasm; Gene Ex

2023
Early Postoperative Treatment versus Initial Observation in CNS WHO Grade 2 and 3 Oligodendroglioma: Clinical Outcomes and DNA Methylation Patterns.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2022, 10-14, Volume: 28, Issue:20

    Topics: Adult; Brain Neoplasms; DNA Methylation; Humans; Isocitrate Dehydrogenase; Lomustine; Methyltransfer

2022
Early Postoperative Treatment versus Initial Observation in CNS WHO Grade 2 and 3 Oligodendroglioma: Clinical Outcomes and DNA Methylation Patterns.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2022, 10-14, Volume: 28, Issue:20

    Topics: Adult; Brain Neoplasms; DNA Methylation; Humans; Isocitrate Dehydrogenase; Lomustine; Methyltransfer

2022
Early Postoperative Treatment versus Initial Observation in CNS WHO Grade 2 and 3 Oligodendroglioma: Clinical Outcomes and DNA Methylation Patterns.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2022, 10-14, Volume: 28, Issue:20

    Topics: Adult; Brain Neoplasms; DNA Methylation; Humans; Isocitrate Dehydrogenase; Lomustine; Methyltransfer

2022
Safety of temozolomide use in adult patients with renal dysfunction.
    Journal of neuro-oncology, 2022, Volume: 159, Issue:3

    Topics: Adult; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Glioma; Humans; Kidney Disea

2022
Safety of temozolomide use in adult patients with renal dysfunction.
    Journal of neuro-oncology, 2022, Volume: 159, Issue:3

    Topics: Adult; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Glioma; Humans; Kidney Disea

2022
Safety of temozolomide use in adult patients with renal dysfunction.
    Journal of neuro-oncology, 2022, Volume: 159, Issue:3

    Topics: Adult; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Glioma; Humans; Kidney Disea

2022
Bio-polymeric transferrin-targeted temozolomide nanoparticles in gel for synergistic post-surgical GBM therapy.
    Nanoscale, 2022, Sep-15, Volume: 14, Issue:35

    Topics: Animals; Brain Neoplasms; Cell Line, Tumor; Delayed-Action Preparations; Glioblastoma; Glioma; Hydro

2022
Bio-polymeric transferrin-targeted temozolomide nanoparticles in gel for synergistic post-surgical GBM therapy.
    Nanoscale, 2022, Sep-15, Volume: 14, Issue:35

    Topics: Animals; Brain Neoplasms; Cell Line, Tumor; Delayed-Action Preparations; Glioblastoma; Glioma; Hydro

2022
Bio-polymeric transferrin-targeted temozolomide nanoparticles in gel for synergistic post-surgical GBM therapy.
    Nanoscale, 2022, Sep-15, Volume: 14, Issue:35

    Topics: Animals; Brain Neoplasms; Cell Line, Tumor; Delayed-Action Preparations; Glioblastoma; Glioma; Hydro

2022
CircKIF4A promotes glioma growth and temozolomide resistance by accelerating glycolysis.
    Cell death & disease, 2022, 08-27, Volume: 13, Issue:8

    Topics: Brain Neoplasms; Cell Line, Tumor; Cell Movement; Cell Proliferation; Drug Resistance, Neoplasm; Fru

2022
CircKIF4A promotes glioma growth and temozolomide resistance by accelerating glycolysis.
    Cell death & disease, 2022, 08-27, Volume: 13, Issue:8

    Topics: Brain Neoplasms; Cell Line, Tumor; Cell Movement; Cell Proliferation; Drug Resistance, Neoplasm; Fru

2022
CircKIF4A promotes glioma growth and temozolomide resistance by accelerating glycolysis.
    Cell death & disease, 2022, 08-27, Volume: 13, Issue:8

    Topics: Brain Neoplasms; Cell Line, Tumor; Cell Movement; Cell Proliferation; Drug Resistance, Neoplasm; Fru

2022
Essential oil of Ligusticum chuanxiong Hort. Regulated P-gp protein and tight junction protein to change pharmacokinetic parameters of temozolomide in blood, brain and tumor.
    Journal of ethnopharmacology, 2022, Nov-15, Volume: 298

    Topics: Animals; Blood-Brain Barrier; Brain Neoplasms; Chromatography, Liquid; Claudin-5; Gas Chromatography

2022
Essential oil of Ligusticum chuanxiong Hort. Regulated P-gp protein and tight junction protein to change pharmacokinetic parameters of temozolomide in blood, brain and tumor.
    Journal of ethnopharmacology, 2022, Nov-15, Volume: 298

    Topics: Animals; Blood-Brain Barrier; Brain Neoplasms; Chromatography, Liquid; Claudin-5; Gas Chromatography

2022
Essential oil of Ligusticum chuanxiong Hort. Regulated P-gp protein and tight junction protein to change pharmacokinetic parameters of temozolomide in blood, brain and tumor.
    Journal of ethnopharmacology, 2022, Nov-15, Volume: 298

    Topics: Animals; Blood-Brain Barrier; Brain Neoplasms; Chromatography, Liquid; Claudin-5; Gas Chromatography

2022
Hypoxia-Driven M2-Polarized Macrophages Facilitate Cancer Aggressiveness and Temozolomide Resistance in Glioblastoma.
    Oxidative medicine and cellular longevity, 2022, Volume: 2022

    Topics: Brain Neoplasms; Cell Line, Tumor; Endothelial Cells; Glioblastoma; Humans; Hypoxia; Macrophages; Ph

2022
Hypoxia-Driven M2-Polarized Macrophages Facilitate Cancer Aggressiveness and Temozolomide Resistance in Glioblastoma.
    Oxidative medicine and cellular longevity, 2022, Volume: 2022

    Topics: Brain Neoplasms; Cell Line, Tumor; Endothelial Cells; Glioblastoma; Humans; Hypoxia; Macrophages; Ph

2022
Hypoxia-Driven M2-Polarized Macrophages Facilitate Cancer Aggressiveness and Temozolomide Resistance in Glioblastoma.
    Oxidative medicine and cellular longevity, 2022, Volume: 2022

    Topics: Brain Neoplasms; Cell Line, Tumor; Endothelial Cells; Glioblastoma; Humans; Hypoxia; Macrophages; Ph

2022
Tissue Niche Miniature of Glioblastoma Patient Treated with Nano-Awakeners to Induce Suicide of Cancer Stem Cells.
    Advanced healthcare materials, 2022, Volume: 11, Issue:21

    Topics: Brain Neoplasms; Cell Line, Tumor; Glioblastoma; Humans; Nanomedicine; Neoplastic Stem Cells; Temozo

2022
Tissue Niche Miniature of Glioblastoma Patient Treated with Nano-Awakeners to Induce Suicide of Cancer Stem Cells.
    Advanced healthcare materials, 2022, Volume: 11, Issue:21

    Topics: Brain Neoplasms; Cell Line, Tumor; Glioblastoma; Humans; Nanomedicine; Neoplastic Stem Cells; Temozo

2022
Tissue Niche Miniature of Glioblastoma Patient Treated with Nano-Awakeners to Induce Suicide of Cancer Stem Cells.
    Advanced healthcare materials, 2022, Volume: 11, Issue:21

    Topics: Brain Neoplasms; Cell Line, Tumor; Glioblastoma; Humans; Nanomedicine; Neoplastic Stem Cells; Temozo

2022
Potentiation of temozolomide activity against glioblastoma cells by aromatase inhibitor letrozole.
    Cancer chemotherapy and pharmacology, 2022, Volume: 90, Issue:4

    Topics: Antineoplastic Agents, Alkylating; Aromatase Inhibitors; Brain Neoplasms; Cell Line, Tumor; Drug Res

2022
Potentiation of temozolomide activity against glioblastoma cells by aromatase inhibitor letrozole.
    Cancer chemotherapy and pharmacology, 2022, Volume: 90, Issue:4

    Topics: Antineoplastic Agents, Alkylating; Aromatase Inhibitors; Brain Neoplasms; Cell Line, Tumor; Drug Res

2022
Potentiation of temozolomide activity against glioblastoma cells by aromatase inhibitor letrozole.
    Cancer chemotherapy and pharmacology, 2022, Volume: 90, Issue:4

    Topics: Antineoplastic Agents, Alkylating; Aromatase Inhibitors; Brain Neoplasms; Cell Line, Tumor; Drug Res

2022
Relapse patterns and radiation dose exposure in IDH wild-type glioblastoma at first radiographic recurrence following chemoradiation.
    Journal of neuro-oncology, 2022, Volume: 160, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Glioblastoma; Humans; Neoplasm Recurrence, Local

2022
Relapse patterns and radiation dose exposure in IDH wild-type glioblastoma at first radiographic recurrence following chemoradiation.
    Journal of neuro-oncology, 2022, Volume: 160, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Glioblastoma; Humans; Neoplasm Recurrence, Local

2022
Relapse patterns and radiation dose exposure in IDH wild-type glioblastoma at first radiographic recurrence following chemoradiation.
    Journal of neuro-oncology, 2022, Volume: 160, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Glioblastoma; Humans; Neoplasm Recurrence, Local

2022
The mechanism of formononetin/calycosin compound optimizing the effects of temozolomide on C6 malignant glioma based on metabolomics and network pharmacology.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2022, Volume: 153

    Topics: Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Drug Resistance, Ne

2022
The mechanism of formononetin/calycosin compound optimizing the effects of temozolomide on C6 malignant glioma based on metabolomics and network pharmacology.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2022, Volume: 153

    Topics: Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Drug Resistance, Ne

2022
The mechanism of formononetin/calycosin compound optimizing the effects of temozolomide on C6 malignant glioma based on metabolomics and network pharmacology.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2022, Volume: 153

    Topics: Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Drug Resistance, Ne

2022
EGFRvⅢ-targeted immunotoxin combined with temozolomide and bispecific antibody for the eradication of established glioblastoma.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2022, Volume: 155

    Topics: Animals; Antibodies, Bispecific; Antibodies, Monoclonal; Brain Neoplasms; Cell Line, Tumor; Glioblas

2022
EGFRvⅢ-targeted immunotoxin combined with temozolomide and bispecific antibody for the eradication of established glioblastoma.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2022, Volume: 155

    Topics: Animals; Antibodies, Bispecific; Antibodies, Monoclonal; Brain Neoplasms; Cell Line, Tumor; Glioblas

2022
EGFRvⅢ-targeted immunotoxin combined with temozolomide and bispecific antibody for the eradication of established glioblastoma.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2022, Volume: 155

    Topics: Animals; Antibodies, Bispecific; Antibodies, Monoclonal; Brain Neoplasms; Cell Line, Tumor; Glioblas

2022
Intrinsic immune evasion patterns predict temozolomide sensitivity and immunotherapy response in lower-grade gliomas.
    BMC cancer, 2022, Sep-12, Volume: 22, Issue:1

    Topics: Brain Neoplasms; Glioma; Humans; Immune Evasion; Immunologic Factors; Immunotherapy; Temozolomide; T

2022
Intrinsic immune evasion patterns predict temozolomide sensitivity and immunotherapy response in lower-grade gliomas.
    BMC cancer, 2022, Sep-12, Volume: 22, Issue:1

    Topics: Brain Neoplasms; Glioma; Humans; Immune Evasion; Immunologic Factors; Immunotherapy; Temozolomide; T

2022
Intrinsic immune evasion patterns predict temozolomide sensitivity and immunotherapy response in lower-grade gliomas.
    BMC cancer, 2022, Sep-12, Volume: 22, Issue:1

    Topics: Brain Neoplasms; Glioma; Humans; Immune Evasion; Immunologic Factors; Immunotherapy; Temozolomide; T

2022
Involvement of cell shape and lipid metabolism in glioblastoma resistance to temozolomide.
    Acta pharmacologica Sinica, 2023, Volume: 44, Issue:3

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Cell Shape; Drug Resistance, N

2023
Involvement of cell shape and lipid metabolism in glioblastoma resistance to temozolomide.
    Acta pharmacologica Sinica, 2023, Volume: 44, Issue:3

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Cell Shape; Drug Resistance, N

2023
Involvement of cell shape and lipid metabolism in glioblastoma resistance to temozolomide.
    Acta pharmacologica Sinica, 2023, Volume: 44, Issue:3

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Cell Shape; Drug Resistance, N

2023
Current therapeutic options for glioblastoma and future perspectives.
    Expert opinion on pharmacotherapy, 2022, Volume: 23, Issue:14

    Topics: Antineoplastic Agents, Alkylating; Bevacizumab; Brain Neoplasms; Combined Modality Therapy; Glioblas

2022
Current therapeutic options for glioblastoma and future perspectives.
    Expert opinion on pharmacotherapy, 2022, Volume: 23, Issue:14

    Topics: Antineoplastic Agents, Alkylating; Bevacizumab; Brain Neoplasms; Combined Modality Therapy; Glioblas

2022
Current therapeutic options for glioblastoma and future perspectives.
    Expert opinion on pharmacotherapy, 2022, Volume: 23, Issue:14

    Topics: Antineoplastic Agents, Alkylating; Bevacizumab; Brain Neoplasms; Combined Modality Therapy; Glioblas

2022
MEX3A Impairs DNA Mismatch Repair Signaling and Mediates Acquired Temozolomide Resistance in Glioblastoma.
    Cancer research, 2022, 11-15, Volume: 82, Issue:22

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Dacarbazine; DNA Mismatch Repa

2022
MEX3A Impairs DNA Mismatch Repair Signaling and Mediates Acquired Temozolomide Resistance in Glioblastoma.
    Cancer research, 2022, 11-15, Volume: 82, Issue:22

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Dacarbazine; DNA Mismatch Repa

2022
MEX3A Impairs DNA Mismatch Repair Signaling and Mediates Acquired Temozolomide Resistance in Glioblastoma.
    Cancer research, 2022, 11-15, Volume: 82, Issue:22

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Dacarbazine; DNA Mismatch Repa

2022
Limited efficacy of temozolomide alone for astrocytoma, IDH-mutant, CNS WHO grades 2 or 3.
    Journal of neuro-oncology, 2022, Volume: 160, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neoplasms; Dacarbazine; Humans; Isocitrate Deh

2022
Limited efficacy of temozolomide alone for astrocytoma, IDH-mutant, CNS WHO grades 2 or 3.
    Journal of neuro-oncology, 2022, Volume: 160, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neoplasms; Dacarbazine; Humans; Isocitrate Deh

2022
Limited efficacy of temozolomide alone for astrocytoma, IDH-mutant, CNS WHO grades 2 or 3.
    Journal of neuro-oncology, 2022, Volume: 160, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neoplasms; Dacarbazine; Humans; Isocitrate Deh

2022
Inhibition of human peptide deformylase by actinonin sensitizes glioblastoma cells to temozolomide chemotherapy.
    Experimental cell research, 2022, 11-15, Volume: 420, Issue:2

    Topics: Amidohydrolases; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; DNA, Mitochon

2022
Inhibition of human peptide deformylase by actinonin sensitizes glioblastoma cells to temozolomide chemotherapy.
    Experimental cell research, 2022, 11-15, Volume: 420, Issue:2

    Topics: Amidohydrolases; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; DNA, Mitochon

2022
Inhibition of human peptide deformylase by actinonin sensitizes glioblastoma cells to temozolomide chemotherapy.
    Experimental cell research, 2022, 11-15, Volume: 420, Issue:2

    Topics: Amidohydrolases; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; DNA, Mitochon

2022
Apatinib and temozolomide in children with recurrent ependymoma: A case report.
    Medicine, 2022, Sep-16, Volume: 101, Issue:37

    Topics: Antineoplastic Agents; Brain Neoplasms; Child; Child, Preschool; Cisplatin; Ependymoma; Humans; Male

2022
Apatinib and temozolomide in children with recurrent ependymoma: A case report.
    Medicine, 2022, Sep-16, Volume: 101, Issue:37

    Topics: Antineoplastic Agents; Brain Neoplasms; Child; Child, Preschool; Cisplatin; Ependymoma; Humans; Male

2022
Apatinib and temozolomide in children with recurrent ependymoma: A case report.
    Medicine, 2022, Sep-16, Volume: 101, Issue:37

    Topics: Antineoplastic Agents; Brain Neoplasms; Child; Child, Preschool; Cisplatin; Ependymoma; Humans; Male

2022
Oncolytic Newcastle Disease Virus Co-Delivered with Modified PLGA Nanoparticles Encapsulating Temozolomide against Glioblastoma Cells: Developing an Effective Treatment Strategy.
    Molecules (Basel, Switzerland), 2022, Sep-06, Volume: 27, Issue:18

    Topics: Acridine Orange; Animals; Antineoplastic Agents; Brain Neoplasms; Cell Line, Tumor; Chick Embryo; Em

2022
Oncolytic Newcastle Disease Virus Co-Delivered with Modified PLGA Nanoparticles Encapsulating Temozolomide against Glioblastoma Cells: Developing an Effective Treatment Strategy.
    Molecules (Basel, Switzerland), 2022, Sep-06, Volume: 27, Issue:18

    Topics: Acridine Orange; Animals; Antineoplastic Agents; Brain Neoplasms; Cell Line, Tumor; Chick Embryo; Em

2022
Oncolytic Newcastle Disease Virus Co-Delivered with Modified PLGA Nanoparticles Encapsulating Temozolomide against Glioblastoma Cells: Developing an Effective Treatment Strategy.
    Molecules (Basel, Switzerland), 2022, Sep-06, Volume: 27, Issue:18

    Topics: Acridine Orange; Animals; Antineoplastic Agents; Brain Neoplasms; Cell Line, Tumor; Chick Embryo; Em

2022
Selenoprotein GPX1 is a prognostic and chemotherapy-related biomarker for brain lower grade glioma.
    Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS), 2022, Volume: 74

    Topics: Biomarkers, Tumor; Brain; Brain Neoplasms; Carcinogens; Glioma; Glutathione Peroxidase; Glutathione

2022
Selenoprotein GPX1 is a prognostic and chemotherapy-related biomarker for brain lower grade glioma.
    Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS), 2022, Volume: 74

    Topics: Biomarkers, Tumor; Brain; Brain Neoplasms; Carcinogens; Glioma; Glutathione Peroxidase; Glutathione

2022
Selenoprotein GPX1 is a prognostic and chemotherapy-related biomarker for brain lower grade glioma.
    Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS), 2022, Volume: 74

    Topics: Biomarkers, Tumor; Brain; Brain Neoplasms; Carcinogens; Glioma; Glutathione Peroxidase; Glutathione

2022
Establishment and characteristics of GWH04, a new primary human glioblastoma cell line.
    International journal of oncology, 2022, Volume: 61, Issue:5

    Topics: Agar; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Glioblastoma; Humans; Telomerase; Temoz

2022
Establishment and characteristics of GWH04, a new primary human glioblastoma cell line.
    International journal of oncology, 2022, Volume: 61, Issue:5

    Topics: Agar; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Glioblastoma; Humans; Telomerase; Temoz

2022
Establishment and characteristics of GWH04, a new primary human glioblastoma cell line.
    International journal of oncology, 2022, Volume: 61, Issue:5

    Topics: Agar; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Glioblastoma; Humans; Telomerase; Temoz

2022
Thymoquinone induces apoptosis in temozolomide-resistant glioblastoma cells via the p38 mitogen-activated protein kinase signaling pathway.
    Environmental toxicology, 2023, Volume: 38, Issue:1

    Topics: Animals; Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Dacarbazin

2023
Thymoquinone induces apoptosis in temozolomide-resistant glioblastoma cells via the p38 mitogen-activated protein kinase signaling pathway.
    Environmental toxicology, 2023, Volume: 38, Issue:1

    Topics: Animals; Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Dacarbazin

2023
Thymoquinone induces apoptosis in temozolomide-resistant glioblastoma cells via the p38 mitogen-activated protein kinase signaling pathway.
    Environmental toxicology, 2023, Volume: 38, Issue:1

    Topics: Animals; Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Dacarbazin

2023
Radiotherapy Plus Temozolomide With or Without Nimotuzumab Against the Newly Diagnosed EGFR-Positive Glioblastoma: A Retrospective Cohort Study.
    The oncologist, 2023, 01-18, Volume: 28, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; ErbB Receptors; Glioblastoma; Human

2023
Radiotherapy Plus Temozolomide With or Without Nimotuzumab Against the Newly Diagnosed EGFR-Positive Glioblastoma: A Retrospective Cohort Study.
    The oncologist, 2023, 01-18, Volume: 28, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; ErbB Receptors; Glioblastoma; Human

2023
Radiotherapy Plus Temozolomide With or Without Nimotuzumab Against the Newly Diagnosed EGFR-Positive Glioblastoma: A Retrospective Cohort Study.
    The oncologist, 2023, 01-18, Volume: 28, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; ErbB Receptors; Glioblastoma; Human

2023
miR-1297 sensitizes glioma cells to temozolomide (TMZ) treatment through targeting adrenomedullin (ADM).
    Journal of translational medicine, 2022, 10-01, Volume: 20, Issue:1

    Topics: Adrenomedullin; Animals; Antineoplastic Agents, Alkylating; Apoptosis; bcl-2-Associated X Protein; B

2022
miR-1297 sensitizes glioma cells to temozolomide (TMZ) treatment through targeting adrenomedullin (ADM).
    Journal of translational medicine, 2022, 10-01, Volume: 20, Issue:1

    Topics: Adrenomedullin; Animals; Antineoplastic Agents, Alkylating; Apoptosis; bcl-2-Associated X Protein; B

2022
miR-1297 sensitizes glioma cells to temozolomide (TMZ) treatment through targeting adrenomedullin (ADM).
    Journal of translational medicine, 2022, 10-01, Volume: 20, Issue:1

    Topics: Adrenomedullin; Animals; Antineoplastic Agents, Alkylating; Apoptosis; bcl-2-Associated X Protein; B

2022
Mechanism of RIP2 enhancing stemness of glioma cells induces temozolomide resistance.
    CNS neuroscience & therapeutics, 2022, Volume: 28, Issue:12

    Topics: Animals; Brain Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; Glioma; Humans; Neoplastic St

2022
Mechanism of RIP2 enhancing stemness of glioma cells induces temozolomide resistance.
    CNS neuroscience & therapeutics, 2022, Volume: 28, Issue:12

    Topics: Animals; Brain Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; Glioma; Humans; Neoplastic St

2022
Mechanism of RIP2 enhancing stemness of glioma cells induces temozolomide resistance.
    CNS neuroscience & therapeutics, 2022, Volume: 28, Issue:12

    Topics: Animals; Brain Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; Glioma; Humans; Neoplastic St

2022
Repurposing an Antiepileptic Drug for the Treatment of Glioblastoma.
    Pharmaceutical research, 2022, Volume: 39, Issue:11

    Topics: Animals; Anticonvulsants; Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cell Line,

2022
Repurposing an Antiepileptic Drug for the Treatment of Glioblastoma.
    Pharmaceutical research, 2022, Volume: 39, Issue:11

    Topics: Animals; Anticonvulsants; Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cell Line,

2022
Repurposing an Antiepileptic Drug for the Treatment of Glioblastoma.
    Pharmaceutical research, 2022, Volume: 39, Issue:11

    Topics: Animals; Anticonvulsants; Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cell Line,

2022
Piperlongumine-inhibited TRIM14 signaling sensitizes glioblastoma cells to temozolomide treatment.
    Life sciences, 2022, Nov-15, Volume: 309

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Dioxolanes; Drug Resistance, N

2022
Piperlongumine-inhibited TRIM14 signaling sensitizes glioblastoma cells to temozolomide treatment.
    Life sciences, 2022, Nov-15, Volume: 309

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Dioxolanes; Drug Resistance, N

2022
Piperlongumine-inhibited TRIM14 signaling sensitizes glioblastoma cells to temozolomide treatment.
    Life sciences, 2022, Nov-15, Volume: 309

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Dioxolanes; Drug Resistance, N

2022
Postmortem study of organ-specific toxicity in glioblastoma patients treated with a combination of temozolomide, irinotecan and bevacizumab.
    Journal of neuro-oncology, 2022, Volume: 160, Issue:1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Brain Neoplasms; Glioblastoma; Glioma;

2022
Postmortem study of organ-specific toxicity in glioblastoma patients treated with a combination of temozolomide, irinotecan and bevacizumab.
    Journal of neuro-oncology, 2022, Volume: 160, Issue:1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Brain Neoplasms; Glioblastoma; Glioma;

2022
Postmortem study of organ-specific toxicity in glioblastoma patients treated with a combination of temozolomide, irinotecan and bevacizumab.
    Journal of neuro-oncology, 2022, Volume: 160, Issue:1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Brain Neoplasms; Glioblastoma; Glioma;

2022
Differential role of Pax6 and its interaction with Shh-Gli1-IDH2 axis in regulation of glioma growth and chemoresistance.
    Journal of biochemical and molecular toxicology, 2023, Volume: 37, Issue:2

    Topics: Brain Neoplasms; Drug Resistance, Neoplasm; Glioma; Hedgehog Proteins; Humans; PAX6 Transcription Fa

2023
Differential role of Pax6 and its interaction with Shh-Gli1-IDH2 axis in regulation of glioma growth and chemoresistance.
    Journal of biochemical and molecular toxicology, 2023, Volume: 37, Issue:2

    Topics: Brain Neoplasms; Drug Resistance, Neoplasm; Glioma; Hedgehog Proteins; Humans; PAX6 Transcription Fa

2023
Differential role of Pax6 and its interaction with Shh-Gli1-IDH2 axis in regulation of glioma growth and chemoresistance.
    Journal of biochemical and molecular toxicology, 2023, Volume: 37, Issue:2

    Topics: Brain Neoplasms; Drug Resistance, Neoplasm; Glioma; Hedgehog Proteins; Humans; PAX6 Transcription Fa

2023
Targeting integrin α2 as potential strategy for radiochemosensitization of glioblastoma.
    Neuro-oncology, 2023, 04-06, Volume: 25, Issue:4

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Drug Resistance, Neop

2023
Targeting integrin α2 as potential strategy for radiochemosensitization of glioblastoma.
    Neuro-oncology, 2023, 04-06, Volume: 25, Issue:4

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Drug Resistance, Neop

2023
Targeting integrin α2 as potential strategy for radiochemosensitization of glioblastoma.
    Neuro-oncology, 2023, 04-06, Volume: 25, Issue:4

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Drug Resistance, Neop

2023
Enzalutamide Induces Apoptotic Insults to Human Drug-Resistant and -Sensitive Glioblastoma Cells via an Intrinsic Bax-Mitochondrion-Cytochrome C Caspase Cascade Activation Pathway.
    Molecules (Basel, Switzerland), 2022, Oct-07, Volume: 27, Issue:19

    Topics: Apoptosis; bcl-2-Associated X Protein; Benzamides; Brain Neoplasms; Caspase 6; Caspase 8; Caspase 9;

2022
Enzalutamide Induces Apoptotic Insults to Human Drug-Resistant and -Sensitive Glioblastoma Cells via an Intrinsic Bax-Mitochondrion-Cytochrome C Caspase Cascade Activation Pathway.
    Molecules (Basel, Switzerland), 2022, Oct-07, Volume: 27, Issue:19

    Topics: Apoptosis; bcl-2-Associated X Protein; Benzamides; Brain Neoplasms; Caspase 6; Caspase 8; Caspase 9;

2022
Enzalutamide Induces Apoptotic Insults to Human Drug-Resistant and -Sensitive Glioblastoma Cells via an Intrinsic Bax-Mitochondrion-Cytochrome C Caspase Cascade Activation Pathway.
    Molecules (Basel, Switzerland), 2022, Oct-07, Volume: 27, Issue:19

    Topics: Apoptosis; bcl-2-Associated X Protein; Benzamides; Brain Neoplasms; Caspase 6; Caspase 8; Caspase 9;

2022
A Sequential Targeting Strategy Interrupts AKT-Driven Subclone-Mediated Progression in Glioblastoma.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2023, 01-17, Volume: 29, Issue:2

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; Gli

2023
A Sequential Targeting Strategy Interrupts AKT-Driven Subclone-Mediated Progression in Glioblastoma.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2023, 01-17, Volume: 29, Issue:2

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; Gli

2023
A Sequential Targeting Strategy Interrupts AKT-Driven Subclone-Mediated Progression in Glioblastoma.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2023, 01-17, Volume: 29, Issue:2

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; Gli

2023
    Zhurnal voprosy neirokhirurgii imeni N. N. Burdenko, 2022, Volume: 86, Issue:5

    Topics: Aged; Astrocytoma; Brain Neoplasms; Carbohydrate Metabolism; Dexamethasone; Glioblastoma; Glioma; Gl

2022
    Zhurnal voprosy neirokhirurgii imeni N. N. Burdenko, 2022, Volume: 86, Issue:5

    Topics: Aged; Astrocytoma; Brain Neoplasms; Carbohydrate Metabolism; Dexamethasone; Glioblastoma; Glioma; Gl

2022
    Zhurnal voprosy neirokhirurgii imeni N. N. Burdenko, 2022, Volume: 86, Issue:5

    Topics: Aged; Astrocytoma; Brain Neoplasms; Carbohydrate Metabolism; Dexamethasone; Glioblastoma; Glioma; Gl

2022
    Zhurnal voprosy neirokhirurgii imeni N. N. Burdenko, 2022, Volume: 86, Issue:5

    Topics: Aged; Astrocytoma; Brain Neoplasms; Carbohydrate Metabolism; Dexamethasone; Glioblastoma; Glioma; Gl

2022
    Zhurnal voprosy neirokhirurgii imeni N. N. Burdenko, 2022, Volume: 86, Issue:5

    Topics: Aged; Astrocytoma; Brain Neoplasms; Carbohydrate Metabolism; Dexamethasone; Glioblastoma; Glioma; Gl

2022
    Zhurnal voprosy neirokhirurgii imeni N. N. Burdenko, 2022, Volume: 86, Issue:5

    Topics: Aged; Astrocytoma; Brain Neoplasms; Carbohydrate Metabolism; Dexamethasone; Glioblastoma; Glioma; Gl

2022
    Zhurnal voprosy neirokhirurgii imeni N. N. Burdenko, 2022, Volume: 86, Issue:5

    Topics: Aged; Astrocytoma; Brain Neoplasms; Carbohydrate Metabolism; Dexamethasone; Glioblastoma; Glioma; Gl

2022
    Zhurnal voprosy neirokhirurgii imeni N. N. Burdenko, 2022, Volume: 86, Issue:5

    Topics: Aged; Astrocytoma; Brain Neoplasms; Carbohydrate Metabolism; Dexamethasone; Glioblastoma; Glioma; Gl

2022
    Zhurnal voprosy neirokhirurgii imeni N. N. Burdenko, 2022, Volume: 86, Issue:5

    Topics: Aged; Astrocytoma; Brain Neoplasms; Carbohydrate Metabolism; Dexamethasone; Glioblastoma; Glioma; Gl

2022
    Zhurnal voprosy neirokhirurgii imeni N. N. Burdenko, 2022, Volume: 86, Issue:5

    Topics: Aged; Astrocytoma; Brain Neoplasms; Carbohydrate Metabolism; Dexamethasone; Glioblastoma; Glioma; Gl

2022
    Zhurnal voprosy neirokhirurgii imeni N. N. Burdenko, 2022, Volume: 86, Issue:5

    Topics: Aged; Astrocytoma; Brain Neoplasms; Carbohydrate Metabolism; Dexamethasone; Glioblastoma; Glioma; Gl

2022
    Zhurnal voprosy neirokhirurgii imeni N. N. Burdenko, 2022, Volume: 86, Issue:5

    Topics: Aged; Astrocytoma; Brain Neoplasms; Carbohydrate Metabolism; Dexamethasone; Glioblastoma; Glioma; Gl

2022
Individualized combination therapies based on whole-exome sequencing displayed significant clinical benefits in a glioblastoma patient with secondary osteosarcoma: case report and genetic characterization.
    BMC neurology, 2022, Oct-21, Volume: 22, Issue:1

    Topics: Bone Neoplasms; Brain Neoplasms; Everolimus; Exome Sequencing; Female; Glioblastoma; Humans; Middle

2022
Individualized combination therapies based on whole-exome sequencing displayed significant clinical benefits in a glioblastoma patient with secondary osteosarcoma: case report and genetic characterization.
    BMC neurology, 2022, Oct-21, Volume: 22, Issue:1

    Topics: Bone Neoplasms; Brain Neoplasms; Everolimus; Exome Sequencing; Female; Glioblastoma; Humans; Middle

2022
Individualized combination therapies based on whole-exome sequencing displayed significant clinical benefits in a glioblastoma patient with secondary osteosarcoma: case report and genetic characterization.
    BMC neurology, 2022, Oct-21, Volume: 22, Issue:1

    Topics: Bone Neoplasms; Brain Neoplasms; Everolimus; Exome Sequencing; Female; Glioblastoma; Humans; Middle

2022
Feasibility of fractionated gamma knife radiosurgery in the management of newly diagnosed Glioblastoma.
    BMC cancer, 2022, Oct-26, Volume: 22, Issue:1

    Topics: Adult; Brain Neoplasms; Feasibility Studies; Female; Glioblastoma; Humans; Male; Prospective Studies

2022
Feasibility of fractionated gamma knife radiosurgery in the management of newly diagnosed Glioblastoma.
    BMC cancer, 2022, Oct-26, Volume: 22, Issue:1

    Topics: Adult; Brain Neoplasms; Feasibility Studies; Female; Glioblastoma; Humans; Male; Prospective Studies

2022
Feasibility of fractionated gamma knife radiosurgery in the management of newly diagnosed Glioblastoma.
    BMC cancer, 2022, Oct-26, Volume: 22, Issue:1

    Topics: Adult; Brain Neoplasms; Feasibility Studies; Female; Glioblastoma; Humans; Male; Prospective Studies

2022
Volumetric Analysis of Glioblastoma for Determining Which CpG Sites Should Be Tested by Pyrosequencing to Predict Temozolomide Efficacy.
    Biomolecules, 2022, Sep-26, Volume: 12, Issue:10

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; DNA; DNA Methylation; DNA Repair Enzymes; Gliobl

2022
Volumetric Analysis of Glioblastoma for Determining Which CpG Sites Should Be Tested by Pyrosequencing to Predict Temozolomide Efficacy.
    Biomolecules, 2022, Sep-26, Volume: 12, Issue:10

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; DNA; DNA Methylation; DNA Repair Enzymes; Gliobl

2022
Volumetric Analysis of Glioblastoma for Determining Which CpG Sites Should Be Tested by Pyrosequencing to Predict Temozolomide Efficacy.
    Biomolecules, 2022, Sep-26, Volume: 12, Issue:10

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; DNA; DNA Methylation; DNA Repair Enzymes; Gliobl

2022
Hsa_circ_0043949 reinforces temozolomide resistance via upregulating oncogene ITGA1 axis in glioblastoma.
    Metabolic brain disease, 2022, Volume: 37, Issue:8

    Topics: Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Drug Resistance, Neoplasm; Gene Expression Re

2022
Hsa_circ_0043949 reinforces temozolomide resistance via upregulating oncogene ITGA1 axis in glioblastoma.
    Metabolic brain disease, 2022, Volume: 37, Issue:8

    Topics: Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Drug Resistance, Neoplasm; Gene Expression Re

2022
Hsa_circ_0043949 reinforces temozolomide resistance via upregulating oncogene ITGA1 axis in glioblastoma.
    Metabolic brain disease, 2022, Volume: 37, Issue:8

    Topics: Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Drug Resistance, Neoplasm; Gene Expression Re

2022
Repurposing FDA-approved drugs as inhibitors of therapy-induced invadopodia activity in glioblastoma cells.
    Molecular and cellular biochemistry, 2023, Volume: 478, Issue:6

    Topics: Brain Neoplasms; Cell Line, Tumor; Drug Repositioning; Glioblastoma; Humans; Temozolomide

2023
Repurposing FDA-approved drugs as inhibitors of therapy-induced invadopodia activity in glioblastoma cells.
    Molecular and cellular biochemistry, 2023, Volume: 478, Issue:6

    Topics: Brain Neoplasms; Cell Line, Tumor; Drug Repositioning; Glioblastoma; Humans; Temozolomide

2023
Repurposing FDA-approved drugs as inhibitors of therapy-induced invadopodia activity in glioblastoma cells.
    Molecular and cellular biochemistry, 2023, Volume: 478, Issue:6

    Topics: Brain Neoplasms; Cell Line, Tumor; Drug Repositioning; Glioblastoma; Humans; Temozolomide

2023
Loss of IDH mutation or secondary tumour manifestation? Evolution of an IDH-mutant and 1p/19q-codeleted oligodendroglioma after 15 years of continuous temozolomide treatment and radiotherapy: A case report.
    Neuropathology and applied neurobiology, 2023, Volume: 49, Issue:1

    Topics: Brain Neoplasms; Chromosomes, Human, Pair 1; Chromosomes, Human, Pair 19; Glioma; Humans; Isocitrate

2023
Loss of IDH mutation or secondary tumour manifestation? Evolution of an IDH-mutant and 1p/19q-codeleted oligodendroglioma after 15 years of continuous temozolomide treatment and radiotherapy: A case report.
    Neuropathology and applied neurobiology, 2023, Volume: 49, Issue:1

    Topics: Brain Neoplasms; Chromosomes, Human, Pair 1; Chromosomes, Human, Pair 19; Glioma; Humans; Isocitrate

2023
Loss of IDH mutation or secondary tumour manifestation? Evolution of an IDH-mutant and 1p/19q-codeleted oligodendroglioma after 15 years of continuous temozolomide treatment and radiotherapy: A case report.
    Neuropathology and applied neurobiology, 2023, Volume: 49, Issue:1

    Topics: Brain Neoplasms; Chromosomes, Human, Pair 1; Chromosomes, Human, Pair 19; Glioma; Humans; Isocitrate

2023
Comprehensive analysis of HHV-6 and HHV-7-related gene signature in prognosis and response to temozolomide of glioma.
    Journal of medical virology, 2023, Volume: 95, Issue:1

    Topics: Brain Neoplasms; F-Box Proteins; Glioma; Herpesvirus 6, Human; Herpesvirus 7, Human; Humans; Prognos

2023
Comprehensive analysis of HHV-6 and HHV-7-related gene signature in prognosis and response to temozolomide of glioma.
    Journal of medical virology, 2023, Volume: 95, Issue:1

    Topics: Brain Neoplasms; F-Box Proteins; Glioma; Herpesvirus 6, Human; Herpesvirus 7, Human; Humans; Prognos

2023
Comprehensive analysis of HHV-6 and HHV-7-related gene signature in prognosis and response to temozolomide of glioma.
    Journal of medical virology, 2023, Volume: 95, Issue:1

    Topics: Brain Neoplasms; F-Box Proteins; Glioma; Herpesvirus 6, Human; Herpesvirus 7, Human; Humans; Prognos

2023
Standard or extended STUPP? Optimal duration of temozolomide for patients with high-grade gliomas: a retrospective analysis.
    Journal of neuro-oncology, 2022, Volume: 160, Issue:2

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Glioblastoma; Glioma; Humans; Retro

2022
Standard or extended STUPP? Optimal duration of temozolomide for patients with high-grade gliomas: a retrospective analysis.
    Journal of neuro-oncology, 2022, Volume: 160, Issue:2

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Glioblastoma; Glioma; Humans; Retro

2022
Standard or extended STUPP? Optimal duration of temozolomide for patients with high-grade gliomas: a retrospective analysis.
    Journal of neuro-oncology, 2022, Volume: 160, Issue:2

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Glioblastoma; Glioma; Humans; Retro

2022
The Significance of
    International journal of molecular sciences, 2022, Oct-27, Volume: 23, Issue:21

    Topics: Brain Neoplasms; DNA Methylation; DNA Modification Methylases; DNA Repair Enzymes; Glioblastoma; Gli

2022
The Significance of
    International journal of molecular sciences, 2022, Oct-27, Volume: 23, Issue:21

    Topics: Brain Neoplasms; DNA Methylation; DNA Modification Methylases; DNA Repair Enzymes; Glioblastoma; Gli

2022
The Significance of
    International journal of molecular sciences, 2022, Oct-27, Volume: 23, Issue:21

    Topics: Brain Neoplasms; DNA Methylation; DNA Modification Methylases; DNA Repair Enzymes; Glioblastoma; Gli

2022
Molecular Docking and Molecular Dynamics Studies Reveal Secretory Proteins as Novel Targets of Temozolomide in Glioblastoma Multiforme.
    Molecules (Basel, Switzerland), 2022, Oct-24, Volume: 27, Issue:21

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; Gli

2022
Molecular Docking and Molecular Dynamics Studies Reveal Secretory Proteins as Novel Targets of Temozolomide in Glioblastoma Multiforme.
    Molecules (Basel, Switzerland), 2022, Oct-24, Volume: 27, Issue:21

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; Gli

2022
Molecular Docking and Molecular Dynamics Studies Reveal Secretory Proteins as Novel Targets of Temozolomide in Glioblastoma Multiforme.
    Molecules (Basel, Switzerland), 2022, Oct-24, Volume: 27, Issue:21

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; Gli

2022
Brain-Targeted HFn-Cu-REGO Nanoplatform for Site-Specific Delivery and Manipulation of Autophagy and Cuproptosis in Glioblastoma.
    Small (Weinheim an der Bergstrasse, Germany), 2023, Volume: 19, Issue:2

    Topics: Apoferritins; Apoptosis; Autophagy; Brain; Brain Neoplasms; Cell Line, Tumor; Copper; Glioblastoma;

2023
Brain-Targeted HFn-Cu-REGO Nanoplatform for Site-Specific Delivery and Manipulation of Autophagy and Cuproptosis in Glioblastoma.
    Small (Weinheim an der Bergstrasse, Germany), 2023, Volume: 19, Issue:2

    Topics: Apoferritins; Apoptosis; Autophagy; Brain; Brain Neoplasms; Cell Line, Tumor; Copper; Glioblastoma;

2023
Brain-Targeted HFn-Cu-REGO Nanoplatform for Site-Specific Delivery and Manipulation of Autophagy and Cuproptosis in Glioblastoma.
    Small (Weinheim an der Bergstrasse, Germany), 2023, Volume: 19, Issue:2

    Topics: Apoferritins; Apoptosis; Autophagy; Brain; Brain Neoplasms; Cell Line, Tumor; Copper; Glioblastoma;

2023
Brain-Targeted HFn-Cu-REGO Nanoplatform for Site-Specific Delivery and Manipulation of Autophagy and Cuproptosis in Glioblastoma.
    Small (Weinheim an der Bergstrasse, Germany), 2023, Volume: 19, Issue:2

    Topics: Apoferritins; Apoptosis; Autophagy; Brain; Brain Neoplasms; Cell Line, Tumor; Copper; Glioblastoma;

2023
Brain-Targeted HFn-Cu-REGO Nanoplatform for Site-Specific Delivery and Manipulation of Autophagy and Cuproptosis in Glioblastoma.
    Small (Weinheim an der Bergstrasse, Germany), 2023, Volume: 19, Issue:2

    Topics: Apoferritins; Apoptosis; Autophagy; Brain; Brain Neoplasms; Cell Line, Tumor; Copper; Glioblastoma;

2023
Brain-Targeted HFn-Cu-REGO Nanoplatform for Site-Specific Delivery and Manipulation of Autophagy and Cuproptosis in Glioblastoma.
    Small (Weinheim an der Bergstrasse, Germany), 2023, Volume: 19, Issue:2

    Topics: Apoferritins; Apoptosis; Autophagy; Brain; Brain Neoplasms; Cell Line, Tumor; Copper; Glioblastoma;

2023
Brain-Targeted HFn-Cu-REGO Nanoplatform for Site-Specific Delivery and Manipulation of Autophagy and Cuproptosis in Glioblastoma.
    Small (Weinheim an der Bergstrasse, Germany), 2023, Volume: 19, Issue:2

    Topics: Apoferritins; Apoptosis; Autophagy; Brain; Brain Neoplasms; Cell Line, Tumor; Copper; Glioblastoma;

2023
Brain-Targeted HFn-Cu-REGO Nanoplatform for Site-Specific Delivery and Manipulation of Autophagy and Cuproptosis in Glioblastoma.
    Small (Weinheim an der Bergstrasse, Germany), 2023, Volume: 19, Issue:2

    Topics: Apoferritins; Apoptosis; Autophagy; Brain; Brain Neoplasms; Cell Line, Tumor; Copper; Glioblastoma;

2023
Brain-Targeted HFn-Cu-REGO Nanoplatform for Site-Specific Delivery and Manipulation of Autophagy and Cuproptosis in Glioblastoma.
    Small (Weinheim an der Bergstrasse, Germany), 2023, Volume: 19, Issue:2

    Topics: Apoferritins; Apoptosis; Autophagy; Brain; Brain Neoplasms; Cell Line, Tumor; Copper; Glioblastoma;

2023
Brain-Targeted HFn-Cu-REGO Nanoplatform for Site-Specific Delivery and Manipulation of Autophagy and Cuproptosis in Glioblastoma.
    Small (Weinheim an der Bergstrasse, Germany), 2023, Volume: 19, Issue:2

    Topics: Apoferritins; Apoptosis; Autophagy; Brain; Brain Neoplasms; Cell Line, Tumor; Copper; Glioblastoma;

2023
Brain-Targeted HFn-Cu-REGO Nanoplatform for Site-Specific Delivery and Manipulation of Autophagy and Cuproptosis in Glioblastoma.
    Small (Weinheim an der Bergstrasse, Germany), 2023, Volume: 19, Issue:2

    Topics: Apoferritins; Apoptosis; Autophagy; Brain; Brain Neoplasms; Cell Line, Tumor; Copper; Glioblastoma;

2023
Brain-Targeted HFn-Cu-REGO Nanoplatform for Site-Specific Delivery and Manipulation of Autophagy and Cuproptosis in Glioblastoma.
    Small (Weinheim an der Bergstrasse, Germany), 2023, Volume: 19, Issue:2

    Topics: Apoferritins; Apoptosis; Autophagy; Brain; Brain Neoplasms; Cell Line, Tumor; Copper; Glioblastoma;

2023
Brain-Targeted HFn-Cu-REGO Nanoplatform for Site-Specific Delivery and Manipulation of Autophagy and Cuproptosis in Glioblastoma.
    Small (Weinheim an der Bergstrasse, Germany), 2023, Volume: 19, Issue:2

    Topics: Apoferritins; Apoptosis; Autophagy; Brain; Brain Neoplasms; Cell Line, Tumor; Copper; Glioblastoma;

2023
Brain-Targeted HFn-Cu-REGO Nanoplatform for Site-Specific Delivery and Manipulation of Autophagy and Cuproptosis in Glioblastoma.
    Small (Weinheim an der Bergstrasse, Germany), 2023, Volume: 19, Issue:2

    Topics: Apoferritins; Apoptosis; Autophagy; Brain; Brain Neoplasms; Cell Line, Tumor; Copper; Glioblastoma;

2023
Brain-Targeted HFn-Cu-REGO Nanoplatform for Site-Specific Delivery and Manipulation of Autophagy and Cuproptosis in Glioblastoma.
    Small (Weinheim an der Bergstrasse, Germany), 2023, Volume: 19, Issue:2

    Topics: Apoferritins; Apoptosis; Autophagy; Brain; Brain Neoplasms; Cell Line, Tumor; Copper; Glioblastoma;

2023
Brain-Targeted HFn-Cu-REGO Nanoplatform for Site-Specific Delivery and Manipulation of Autophagy and Cuproptosis in Glioblastoma.
    Small (Weinheim an der Bergstrasse, Germany), 2023, Volume: 19, Issue:2

    Topics: Apoferritins; Apoptosis; Autophagy; Brain; Brain Neoplasms; Cell Line, Tumor; Copper; Glioblastoma;

2023
Brain-Targeted HFn-Cu-REGO Nanoplatform for Site-Specific Delivery and Manipulation of Autophagy and Cuproptosis in Glioblastoma.
    Small (Weinheim an der Bergstrasse, Germany), 2023, Volume: 19, Issue:2

    Topics: Apoferritins; Apoptosis; Autophagy; Brain; Brain Neoplasms; Cell Line, Tumor; Copper; Glioblastoma;

2023
Brain-Targeted HFn-Cu-REGO Nanoplatform for Site-Specific Delivery and Manipulation of Autophagy and Cuproptosis in Glioblastoma.
    Small (Weinheim an der Bergstrasse, Germany), 2023, Volume: 19, Issue:2

    Topics: Apoferritins; Apoptosis; Autophagy; Brain; Brain Neoplasms; Cell Line, Tumor; Copper; Glioblastoma;

2023
Brain-Targeted HFn-Cu-REGO Nanoplatform for Site-Specific Delivery and Manipulation of Autophagy and Cuproptosis in Glioblastoma.
    Small (Weinheim an der Bergstrasse, Germany), 2023, Volume: 19, Issue:2

    Topics: Apoferritins; Apoptosis; Autophagy; Brain; Brain Neoplasms; Cell Line, Tumor; Copper; Glioblastoma;

2023
Brain-Targeted HFn-Cu-REGO Nanoplatform for Site-Specific Delivery and Manipulation of Autophagy and Cuproptosis in Glioblastoma.
    Small (Weinheim an der Bergstrasse, Germany), 2023, Volume: 19, Issue:2

    Topics: Apoferritins; Apoptosis; Autophagy; Brain; Brain Neoplasms; Cell Line, Tumor; Copper; Glioblastoma;

2023
Brain-Targeted HFn-Cu-REGO Nanoplatform for Site-Specific Delivery and Manipulation of Autophagy and Cuproptosis in Glioblastoma.
    Small (Weinheim an der Bergstrasse, Germany), 2023, Volume: 19, Issue:2

    Topics: Apoferritins; Apoptosis; Autophagy; Brain; Brain Neoplasms; Cell Line, Tumor; Copper; Glioblastoma;

2023
Brain-Targeted HFn-Cu-REGO Nanoplatform for Site-Specific Delivery and Manipulation of Autophagy and Cuproptosis in Glioblastoma.
    Small (Weinheim an der Bergstrasse, Germany), 2023, Volume: 19, Issue:2

    Topics: Apoferritins; Apoptosis; Autophagy; Brain; Brain Neoplasms; Cell Line, Tumor; Copper; Glioblastoma;

2023
Brain-Targeted HFn-Cu-REGO Nanoplatform for Site-Specific Delivery and Manipulation of Autophagy and Cuproptosis in Glioblastoma.
    Small (Weinheim an der Bergstrasse, Germany), 2023, Volume: 19, Issue:2

    Topics: Apoferritins; Apoptosis; Autophagy; Brain; Brain Neoplasms; Cell Line, Tumor; Copper; Glioblastoma;

2023
Brain-Targeted HFn-Cu-REGO Nanoplatform for Site-Specific Delivery and Manipulation of Autophagy and Cuproptosis in Glioblastoma.
    Small (Weinheim an der Bergstrasse, Germany), 2023, Volume: 19, Issue:2

    Topics: Apoferritins; Apoptosis; Autophagy; Brain; Brain Neoplasms; Cell Line, Tumor; Copper; Glioblastoma;

2023
Brain-Targeted HFn-Cu-REGO Nanoplatform for Site-Specific Delivery and Manipulation of Autophagy and Cuproptosis in Glioblastoma.
    Small (Weinheim an der Bergstrasse, Germany), 2023, Volume: 19, Issue:2

    Topics: Apoferritins; Apoptosis; Autophagy; Brain; Brain Neoplasms; Cell Line, Tumor; Copper; Glioblastoma;

2023
Brain-Targeted HFn-Cu-REGO Nanoplatform for Site-Specific Delivery and Manipulation of Autophagy and Cuproptosis in Glioblastoma.
    Small (Weinheim an der Bergstrasse, Germany), 2023, Volume: 19, Issue:2

    Topics: Apoferritins; Apoptosis; Autophagy; Brain; Brain Neoplasms; Cell Line, Tumor; Copper; Glioblastoma;

2023
Brain-Targeted HFn-Cu-REGO Nanoplatform for Site-Specific Delivery and Manipulation of Autophagy and Cuproptosis in Glioblastoma.
    Small (Weinheim an der Bergstrasse, Germany), 2023, Volume: 19, Issue:2

    Topics: Apoferritins; Apoptosis; Autophagy; Brain; Brain Neoplasms; Cell Line, Tumor; Copper; Glioblastoma;

2023
Remdesivir inhibits the progression of glioblastoma by enhancing endoplasmic reticulum stress.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2023, Volume: 157

    Topics: Animals; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Endoplasmic Reticulum Stress; Glioblastoma; M

2023
Remdesivir inhibits the progression of glioblastoma by enhancing endoplasmic reticulum stress.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2023, Volume: 157

    Topics: Animals; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Endoplasmic Reticulum Stress; Glioblastoma; M

2023
Remdesivir inhibits the progression of glioblastoma by enhancing endoplasmic reticulum stress.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2023, Volume: 157

    Topics: Animals; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Endoplasmic Reticulum Stress; Glioblastoma; M

2023
Remdesivir inhibits the progression of glioblastoma by enhancing endoplasmic reticulum stress.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2023, Volume: 157

    Topics: Animals; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Endoplasmic Reticulum Stress; Glioblastoma; M

2023
Remdesivir inhibits the progression of glioblastoma by enhancing endoplasmic reticulum stress.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2023, Volume: 157

    Topics: Animals; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Endoplasmic Reticulum Stress; Glioblastoma; M

2023
Remdesivir inhibits the progression of glioblastoma by enhancing endoplasmic reticulum stress.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2023, Volume: 157

    Topics: Animals; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Endoplasmic Reticulum Stress; Glioblastoma; M

2023
Remdesivir inhibits the progression of glioblastoma by enhancing endoplasmic reticulum stress.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2023, Volume: 157

    Topics: Animals; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Endoplasmic Reticulum Stress; Glioblastoma; M

2023
Remdesivir inhibits the progression of glioblastoma by enhancing endoplasmic reticulum stress.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2023, Volume: 157

    Topics: Animals; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Endoplasmic Reticulum Stress; Glioblastoma; M

2023
Remdesivir inhibits the progression of glioblastoma by enhancing endoplasmic reticulum stress.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2023, Volume: 157

    Topics: Animals; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Endoplasmic Reticulum Stress; Glioblastoma; M

2023
Remdesivir inhibits the progression of glioblastoma by enhancing endoplasmic reticulum stress.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2023, Volume: 157

    Topics: Animals; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Endoplasmic Reticulum Stress; Glioblastoma; M

2023
Remdesivir inhibits the progression of glioblastoma by enhancing endoplasmic reticulum stress.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2023, Volume: 157

    Topics: Animals; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Endoplasmic Reticulum Stress; Glioblastoma; M

2023
Remdesivir inhibits the progression of glioblastoma by enhancing endoplasmic reticulum stress.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2023, Volume: 157

    Topics: Animals; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Endoplasmic Reticulum Stress; Glioblastoma; M

2023
Remdesivir inhibits the progression of glioblastoma by enhancing endoplasmic reticulum stress.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2023, Volume: 157

    Topics: Animals; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Endoplasmic Reticulum Stress; Glioblastoma; M

2023
Remdesivir inhibits the progression of glioblastoma by enhancing endoplasmic reticulum stress.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2023, Volume: 157

    Topics: Animals; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Endoplasmic Reticulum Stress; Glioblastoma; M

2023
Remdesivir inhibits the progression of glioblastoma by enhancing endoplasmic reticulum stress.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2023, Volume: 157

    Topics: Animals; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Endoplasmic Reticulum Stress; Glioblastoma; M

2023
Remdesivir inhibits the progression of glioblastoma by enhancing endoplasmic reticulum stress.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2023, Volume: 157

    Topics: Animals; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Endoplasmic Reticulum Stress; Glioblastoma; M

2023
Remdesivir inhibits the progression of glioblastoma by enhancing endoplasmic reticulum stress.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2023, Volume: 157

    Topics: Animals; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Endoplasmic Reticulum Stress; Glioblastoma; M

2023
Remdesivir inhibits the progression of glioblastoma by enhancing endoplasmic reticulum stress.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2023, Volume: 157

    Topics: Animals; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Endoplasmic Reticulum Stress; Glioblastoma; M

2023
Remdesivir inhibits the progression of glioblastoma by enhancing endoplasmic reticulum stress.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2023, Volume: 157

    Topics: Animals; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Endoplasmic Reticulum Stress; Glioblastoma; M

2023
Remdesivir inhibits the progression of glioblastoma by enhancing endoplasmic reticulum stress.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2023, Volume: 157

    Topics: Animals; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Endoplasmic Reticulum Stress; Glioblastoma; M

2023
Remdesivir inhibits the progression of glioblastoma by enhancing endoplasmic reticulum stress.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2023, Volume: 157

    Topics: Animals; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Endoplasmic Reticulum Stress; Glioblastoma; M

2023
Remdesivir inhibits the progression of glioblastoma by enhancing endoplasmic reticulum stress.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2023, Volume: 157

    Topics: Animals; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Endoplasmic Reticulum Stress; Glioblastoma; M

2023
Remdesivir inhibits the progression of glioblastoma by enhancing endoplasmic reticulum stress.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2023, Volume: 157

    Topics: Animals; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Endoplasmic Reticulum Stress; Glioblastoma; M

2023
Remdesivir inhibits the progression of glioblastoma by enhancing endoplasmic reticulum stress.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2023, Volume: 157

    Topics: Animals; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Endoplasmic Reticulum Stress; Glioblastoma; M

2023
Remdesivir inhibits the progression of glioblastoma by enhancing endoplasmic reticulum stress.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2023, Volume: 157

    Topics: Animals; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Endoplasmic Reticulum Stress; Glioblastoma; M

2023
Remdesivir inhibits the progression of glioblastoma by enhancing endoplasmic reticulum stress.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2023, Volume: 157

    Topics: Animals; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Endoplasmic Reticulum Stress; Glioblastoma; M

2023
Remdesivir inhibits the progression of glioblastoma by enhancing endoplasmic reticulum stress.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2023, Volume: 157

    Topics: Animals; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Endoplasmic Reticulum Stress; Glioblastoma; M

2023
Plasma IL13Rα2 as a novel liquid biopsy biomarker for glioblastoma.
    Journal of neuro-oncology, 2022, Volume: 160, Issue:3

    Topics: Biomarkers; Brain Neoplasms; Disease Progression; Glioblastoma; Humans; Interleukin-13 Receptor alph

2022
Plasma IL13Rα2 as a novel liquid biopsy biomarker for glioblastoma.
    Journal of neuro-oncology, 2022, Volume: 160, Issue:3

    Topics: Biomarkers; Brain Neoplasms; Disease Progression; Glioblastoma; Humans; Interleukin-13 Receptor alph

2022
Plasma IL13Rα2 as a novel liquid biopsy biomarker for glioblastoma.
    Journal of neuro-oncology, 2022, Volume: 160, Issue:3

    Topics: Biomarkers; Brain Neoplasms; Disease Progression; Glioblastoma; Humans; Interleukin-13 Receptor alph

2022
Plasma IL13Rα2 as a novel liquid biopsy biomarker for glioblastoma.
    Journal of neuro-oncology, 2022, Volume: 160, Issue:3

    Topics: Biomarkers; Brain Neoplasms; Disease Progression; Glioblastoma; Humans; Interleukin-13 Receptor alph

2022
Plasma IL13Rα2 as a novel liquid biopsy biomarker for glioblastoma.
    Journal of neuro-oncology, 2022, Volume: 160, Issue:3

    Topics: Biomarkers; Brain Neoplasms; Disease Progression; Glioblastoma; Humans; Interleukin-13 Receptor alph

2022
Plasma IL13Rα2 as a novel liquid biopsy biomarker for glioblastoma.
    Journal of neuro-oncology, 2022, Volume: 160, Issue:3

    Topics: Biomarkers; Brain Neoplasms; Disease Progression; Glioblastoma; Humans; Interleukin-13 Receptor alph

2022
Plasma IL13Rα2 as a novel liquid biopsy biomarker for glioblastoma.
    Journal of neuro-oncology, 2022, Volume: 160, Issue:3

    Topics: Biomarkers; Brain Neoplasms; Disease Progression; Glioblastoma; Humans; Interleukin-13 Receptor alph

2022
Plasma IL13Rα2 as a novel liquid biopsy biomarker for glioblastoma.
    Journal of neuro-oncology, 2022, Volume: 160, Issue:3

    Topics: Biomarkers; Brain Neoplasms; Disease Progression; Glioblastoma; Humans; Interleukin-13 Receptor alph

2022
Plasma IL13Rα2 as a novel liquid biopsy biomarker for glioblastoma.
    Journal of neuro-oncology, 2022, Volume: 160, Issue:3

    Topics: Biomarkers; Brain Neoplasms; Disease Progression; Glioblastoma; Humans; Interleukin-13 Receptor alph

2022
Plasma IL13Rα2 as a novel liquid biopsy biomarker for glioblastoma.
    Journal of neuro-oncology, 2022, Volume: 160, Issue:3

    Topics: Biomarkers; Brain Neoplasms; Disease Progression; Glioblastoma; Humans; Interleukin-13 Receptor alph

2022
Plasma IL13Rα2 as a novel liquid biopsy biomarker for glioblastoma.
    Journal of neuro-oncology, 2022, Volume: 160, Issue:3

    Topics: Biomarkers; Brain Neoplasms; Disease Progression; Glioblastoma; Humans; Interleukin-13 Receptor alph

2022
Plasma IL13Rα2 as a novel liquid biopsy biomarker for glioblastoma.
    Journal of neuro-oncology, 2022, Volume: 160, Issue:3

    Topics: Biomarkers; Brain Neoplasms; Disease Progression; Glioblastoma; Humans; Interleukin-13 Receptor alph

2022
Plasma IL13Rα2 as a novel liquid biopsy biomarker for glioblastoma.
    Journal of neuro-oncology, 2022, Volume: 160, Issue:3

    Topics: Biomarkers; Brain Neoplasms; Disease Progression; Glioblastoma; Humans; Interleukin-13 Receptor alph

2022
Plasma IL13Rα2 as a novel liquid biopsy biomarker for glioblastoma.
    Journal of neuro-oncology, 2022, Volume: 160, Issue:3

    Topics: Biomarkers; Brain Neoplasms; Disease Progression; Glioblastoma; Humans; Interleukin-13 Receptor alph

2022
Plasma IL13Rα2 as a novel liquid biopsy biomarker for glioblastoma.
    Journal of neuro-oncology, 2022, Volume: 160, Issue:3

    Topics: Biomarkers; Brain Neoplasms; Disease Progression; Glioblastoma; Humans; Interleukin-13 Receptor alph

2022
Plasma IL13Rα2 as a novel liquid biopsy biomarker for glioblastoma.
    Journal of neuro-oncology, 2022, Volume: 160, Issue:3

    Topics: Biomarkers; Brain Neoplasms; Disease Progression; Glioblastoma; Humans; Interleukin-13 Receptor alph

2022
Plasma IL13Rα2 as a novel liquid biopsy biomarker for glioblastoma.
    Journal of neuro-oncology, 2022, Volume: 160, Issue:3

    Topics: Biomarkers; Brain Neoplasms; Disease Progression; Glioblastoma; Humans; Interleukin-13 Receptor alph

2022
Plasma IL13Rα2 as a novel liquid biopsy biomarker for glioblastoma.
    Journal of neuro-oncology, 2022, Volume: 160, Issue:3

    Topics: Biomarkers; Brain Neoplasms; Disease Progression; Glioblastoma; Humans; Interleukin-13 Receptor alph

2022
Plasma IL13Rα2 as a novel liquid biopsy biomarker for glioblastoma.
    Journal of neuro-oncology, 2022, Volume: 160, Issue:3

    Topics: Biomarkers; Brain Neoplasms; Disease Progression; Glioblastoma; Humans; Interleukin-13 Receptor alph

2022
Plasma IL13Rα2 as a novel liquid biopsy biomarker for glioblastoma.
    Journal of neuro-oncology, 2022, Volume: 160, Issue:3

    Topics: Biomarkers; Brain Neoplasms; Disease Progression; Glioblastoma; Humans; Interleukin-13 Receptor alph

2022
Plasma IL13Rα2 as a novel liquid biopsy biomarker for glioblastoma.
    Journal of neuro-oncology, 2022, Volume: 160, Issue:3

    Topics: Biomarkers; Brain Neoplasms; Disease Progression; Glioblastoma; Humans; Interleukin-13 Receptor alph

2022
Plasma IL13Rα2 as a novel liquid biopsy biomarker for glioblastoma.
    Journal of neuro-oncology, 2022, Volume: 160, Issue:3

    Topics: Biomarkers; Brain Neoplasms; Disease Progression; Glioblastoma; Humans; Interleukin-13 Receptor alph

2022
Plasma IL13Rα2 as a novel liquid biopsy biomarker for glioblastoma.
    Journal of neuro-oncology, 2022, Volume: 160, Issue:3

    Topics: Biomarkers; Brain Neoplasms; Disease Progression; Glioblastoma; Humans; Interleukin-13 Receptor alph

2022
Plasma IL13Rα2 as a novel liquid biopsy biomarker for glioblastoma.
    Journal of neuro-oncology, 2022, Volume: 160, Issue:3

    Topics: Biomarkers; Brain Neoplasms; Disease Progression; Glioblastoma; Humans; Interleukin-13 Receptor alph

2022
Plasma IL13Rα2 as a novel liquid biopsy biomarker for glioblastoma.
    Journal of neuro-oncology, 2022, Volume: 160, Issue:3

    Topics: Biomarkers; Brain Neoplasms; Disease Progression; Glioblastoma; Humans; Interleukin-13 Receptor alph

2022
Plasma IL13Rα2 as a novel liquid biopsy biomarker for glioblastoma.
    Journal of neuro-oncology, 2022, Volume: 160, Issue:3

    Topics: Biomarkers; Brain Neoplasms; Disease Progression; Glioblastoma; Humans; Interleukin-13 Receptor alph

2022
Plasma IL13Rα2 as a novel liquid biopsy biomarker for glioblastoma.
    Journal of neuro-oncology, 2022, Volume: 160, Issue:3

    Topics: Biomarkers; Brain Neoplasms; Disease Progression; Glioblastoma; Humans; Interleukin-13 Receptor alph

2022
The Effect of Hydroquinidine on Proliferation and Apoptosis of TMZ-sensitive and -resistant GBM Cells.
    Anti-cancer agents in medicinal chemistry, 2023, Volume: 23, Issue:8

    Topics: Animals; Anticarcinogenic Agents; Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cel

2023
The Effect of Hydroquinidine on Proliferation and Apoptosis of TMZ-sensitive and -resistant GBM Cells.
    Anti-cancer agents in medicinal chemistry, 2023, Volume: 23, Issue:8

    Topics: Animals; Anticarcinogenic Agents; Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cel

2023
The Effect of Hydroquinidine on Proliferation and Apoptosis of TMZ-sensitive and -resistant GBM Cells.
    Anti-cancer agents in medicinal chemistry, 2023, Volume: 23, Issue:8

    Topics: Animals; Anticarcinogenic Agents; Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cel

2023
The Effect of Hydroquinidine on Proliferation and Apoptosis of TMZ-sensitive and -resistant GBM Cells.
    Anti-cancer agents in medicinal chemistry, 2023, Volume: 23, Issue:8

    Topics: Animals; Anticarcinogenic Agents; Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cel

2023
The Effect of Hydroquinidine on Proliferation and Apoptosis of TMZ-sensitive and -resistant GBM Cells.
    Anti-cancer agents in medicinal chemistry, 2023, Volume: 23, Issue:8

    Topics: Animals; Anticarcinogenic Agents; Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cel

2023
The Effect of Hydroquinidine on Proliferation and Apoptosis of TMZ-sensitive and -resistant GBM Cells.
    Anti-cancer agents in medicinal chemistry, 2023, Volume: 23, Issue:8

    Topics: Animals; Anticarcinogenic Agents; Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cel

2023
The Effect of Hydroquinidine on Proliferation and Apoptosis of TMZ-sensitive and -resistant GBM Cells.
    Anti-cancer agents in medicinal chemistry, 2023, Volume: 23, Issue:8

    Topics: Animals; Anticarcinogenic Agents; Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cel

2023
The Effect of Hydroquinidine on Proliferation and Apoptosis of TMZ-sensitive and -resistant GBM Cells.
    Anti-cancer agents in medicinal chemistry, 2023, Volume: 23, Issue:8

    Topics: Animals; Anticarcinogenic Agents; Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cel

2023
The Effect of Hydroquinidine on Proliferation and Apoptosis of TMZ-sensitive and -resistant GBM Cells.
    Anti-cancer agents in medicinal chemistry, 2023, Volume: 23, Issue:8

    Topics: Animals; Anticarcinogenic Agents; Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cel

2023
The Effect of Hydroquinidine on Proliferation and Apoptosis of TMZ-sensitive and -resistant GBM Cells.
    Anti-cancer agents in medicinal chemistry, 2023, Volume: 23, Issue:8

    Topics: Animals; Anticarcinogenic Agents; Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cel

2023
The Effect of Hydroquinidine on Proliferation and Apoptosis of TMZ-sensitive and -resistant GBM Cells.
    Anti-cancer agents in medicinal chemistry, 2023, Volume: 23, Issue:8

    Topics: Animals; Anticarcinogenic Agents; Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cel

2023
The Effect of Hydroquinidine on Proliferation and Apoptosis of TMZ-sensitive and -resistant GBM Cells.
    Anti-cancer agents in medicinal chemistry, 2023, Volume: 23, Issue:8

    Topics: Animals; Anticarcinogenic Agents; Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cel

2023
The Effect of Hydroquinidine on Proliferation and Apoptosis of TMZ-sensitive and -resistant GBM Cells.
    Anti-cancer agents in medicinal chemistry, 2023, Volume: 23, Issue:8

    Topics: Animals; Anticarcinogenic Agents; Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cel

2023
The Effect of Hydroquinidine on Proliferation and Apoptosis of TMZ-sensitive and -resistant GBM Cells.
    Anti-cancer agents in medicinal chemistry, 2023, Volume: 23, Issue:8

    Topics: Animals; Anticarcinogenic Agents; Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cel

2023
The Effect of Hydroquinidine on Proliferation and Apoptosis of TMZ-sensitive and -resistant GBM Cells.
    Anti-cancer agents in medicinal chemistry, 2023, Volume: 23, Issue:8

    Topics: Animals; Anticarcinogenic Agents; Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cel

2023
The Effect of Hydroquinidine on Proliferation and Apoptosis of TMZ-sensitive and -resistant GBM Cells.
    Anti-cancer agents in medicinal chemistry, 2023, Volume: 23, Issue:8

    Topics: Animals; Anticarcinogenic Agents; Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cel

2023
The Effect of Hydroquinidine on Proliferation and Apoptosis of TMZ-sensitive and -resistant GBM Cells.
    Anti-cancer agents in medicinal chemistry, 2023, Volume: 23, Issue:8

    Topics: Animals; Anticarcinogenic Agents; Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cel

2023
The Effect of Hydroquinidine on Proliferation and Apoptosis of TMZ-sensitive and -resistant GBM Cells.
    Anti-cancer agents in medicinal chemistry, 2023, Volume: 23, Issue:8

    Topics: Animals; Anticarcinogenic Agents; Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cel

2023
The Effect of Hydroquinidine on Proliferation and Apoptosis of TMZ-sensitive and -resistant GBM Cells.
    Anti-cancer agents in medicinal chemistry, 2023, Volume: 23, Issue:8

    Topics: Animals; Anticarcinogenic Agents; Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cel

2023
The Effect of Hydroquinidine on Proliferation and Apoptosis of TMZ-sensitive and -resistant GBM Cells.
    Anti-cancer agents in medicinal chemistry, 2023, Volume: 23, Issue:8

    Topics: Animals; Anticarcinogenic Agents; Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cel

2023
The Effect of Hydroquinidine on Proliferation and Apoptosis of TMZ-sensitive and -resistant GBM Cells.
    Anti-cancer agents in medicinal chemistry, 2023, Volume: 23, Issue:8

    Topics: Animals; Anticarcinogenic Agents; Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cel

2023
The Effect of Hydroquinidine on Proliferation and Apoptosis of TMZ-sensitive and -resistant GBM Cells.
    Anti-cancer agents in medicinal chemistry, 2023, Volume: 23, Issue:8

    Topics: Animals; Anticarcinogenic Agents; Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cel

2023
The Effect of Hydroquinidine on Proliferation and Apoptosis of TMZ-sensitive and -resistant GBM Cells.
    Anti-cancer agents in medicinal chemistry, 2023, Volume: 23, Issue:8

    Topics: Animals; Anticarcinogenic Agents; Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cel

2023
The Effect of Hydroquinidine on Proliferation and Apoptosis of TMZ-sensitive and -resistant GBM Cells.
    Anti-cancer agents in medicinal chemistry, 2023, Volume: 23, Issue:8

    Topics: Animals; Anticarcinogenic Agents; Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cel

2023
The Effect of Hydroquinidine on Proliferation and Apoptosis of TMZ-sensitive and -resistant GBM Cells.
    Anti-cancer agents in medicinal chemistry, 2023, Volume: 23, Issue:8

    Topics: Animals; Anticarcinogenic Agents; Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cel

2023
The Effect of Hydroquinidine on Proliferation and Apoptosis of TMZ-sensitive and -resistant GBM Cells.
    Anti-cancer agents in medicinal chemistry, 2023, Volume: 23, Issue:8

    Topics: Animals; Anticarcinogenic Agents; Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cel

2023
The Effect of Hydroquinidine on Proliferation and Apoptosis of TMZ-sensitive and -resistant GBM Cells.
    Anti-cancer agents in medicinal chemistry, 2023, Volume: 23, Issue:8

    Topics: Animals; Anticarcinogenic Agents; Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cel

2023
Stellettin B Sensitizes Glioblastoma to DNA-Damaging Treatments by Suppressing PI3K-Mediated Homologous Recombination Repair.
    Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2023, Volume: 10, Issue:3

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; DNA Damage; Drug Resistanc

2023
Stellettin B Sensitizes Glioblastoma to DNA-Damaging Treatments by Suppressing PI3K-Mediated Homologous Recombination Repair.
    Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2023, Volume: 10, Issue:3

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; DNA Damage; Drug Resistanc

2023
Stellettin B Sensitizes Glioblastoma to DNA-Damaging Treatments by Suppressing PI3K-Mediated Homologous Recombination Repair.
    Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2023, Volume: 10, Issue:3

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; DNA Damage; Drug Resistanc

2023
Stellettin B Sensitizes Glioblastoma to DNA-Damaging Treatments by Suppressing PI3K-Mediated Homologous Recombination Repair.
    Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2023, Volume: 10, Issue:3

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; DNA Damage; Drug Resistanc

2023
Stellettin B Sensitizes Glioblastoma to DNA-Damaging Treatments by Suppressing PI3K-Mediated Homologous Recombination Repair.
    Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2023, Volume: 10, Issue:3

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; DNA Damage; Drug Resistanc

2023
Stellettin B Sensitizes Glioblastoma to DNA-Damaging Treatments by Suppressing PI3K-Mediated Homologous Recombination Repair.
    Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2023, Volume: 10, Issue:3

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; DNA Damage; Drug Resistanc

2023
Stellettin B Sensitizes Glioblastoma to DNA-Damaging Treatments by Suppressing PI3K-Mediated Homologous Recombination Repair.
    Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2023, Volume: 10, Issue:3

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; DNA Damage; Drug Resistanc

2023
Stellettin B Sensitizes Glioblastoma to DNA-Damaging Treatments by Suppressing PI3K-Mediated Homologous Recombination Repair.
    Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2023, Volume: 10, Issue:3

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; DNA Damage; Drug Resistanc

2023
Stellettin B Sensitizes Glioblastoma to DNA-Damaging Treatments by Suppressing PI3K-Mediated Homologous Recombination Repair.
    Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2023, Volume: 10, Issue:3

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; DNA Damage; Drug Resistanc

2023
Stellettin B Sensitizes Glioblastoma to DNA-Damaging Treatments by Suppressing PI3K-Mediated Homologous Recombination Repair.
    Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2023, Volume: 10, Issue:3

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; DNA Damage; Drug Resistanc

2023
Stellettin B Sensitizes Glioblastoma to DNA-Damaging Treatments by Suppressing PI3K-Mediated Homologous Recombination Repair.
    Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2023, Volume: 10, Issue:3

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; DNA Damage; Drug Resistanc

2023
Stellettin B Sensitizes Glioblastoma to DNA-Damaging Treatments by Suppressing PI3K-Mediated Homologous Recombination Repair.
    Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2023, Volume: 10, Issue:3

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; DNA Damage; Drug Resistanc

2023
Safe administration of temozolomide in end-stage renal disease patients.
    Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners, 2023, Volume: 29, Issue:4

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Central Nervous System Neoplasms; Glioblastoma;

2023
Safe administration of temozolomide in end-stage renal disease patients.
    Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners, 2023, Volume: 29, Issue:4

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Central Nervous System Neoplasms; Glioblastoma;

2023
Safe administration of temozolomide in end-stage renal disease patients.
    Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners, 2023, Volume: 29, Issue:4

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Central Nervous System Neoplasms; Glioblastoma;

2023
Safe administration of temozolomide in end-stage renal disease patients.
    Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners, 2023, Volume: 29, Issue:4

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Central Nervous System Neoplasms; Glioblastoma;

2023
Safe administration of temozolomide in end-stage renal disease patients.
    Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners, 2023, Volume: 29, Issue:4

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Central Nervous System Neoplasms; Glioblastoma;

2023
Safe administration of temozolomide in end-stage renal disease patients.
    Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners, 2023, Volume: 29, Issue:4

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Central Nervous System Neoplasms; Glioblastoma;

2023
Safe administration of temozolomide in end-stage renal disease patients.
    Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners, 2023, Volume: 29, Issue:4

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Central Nervous System Neoplasms; Glioblastoma;

2023
Safe administration of temozolomide in end-stage renal disease patients.
    Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners, 2023, Volume: 29, Issue:4

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Central Nervous System Neoplasms; Glioblastoma;

2023
Safe administration of temozolomide in end-stage renal disease patients.
    Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners, 2023, Volume: 29, Issue:4

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Central Nervous System Neoplasms; Glioblastoma;

2023
Safe administration of temozolomide in end-stage renal disease patients.
    Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners, 2023, Volume: 29, Issue:4

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Central Nervous System Neoplasms; Glioblastoma;

2023
Safe administration of temozolomide in end-stage renal disease patients.
    Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners, 2023, Volume: 29, Issue:4

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Central Nervous System Neoplasms; Glioblastoma;

2023
Safe administration of temozolomide in end-stage renal disease patients.
    Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners, 2023, Volume: 29, Issue:4

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Central Nervous System Neoplasms; Glioblastoma;

2023
Ruxolitinib enhances cytotoxic and apoptotic effects of temozolomide on glioblastoma cells by regulating WNT signaling pathway-related genes.
    Medical oncology (Northwood, London, England), 2022, Dec-02, Volume: 40, Issue:1

    Topics: Antineoplastic Agents; Brain Neoplasms; Glioblastoma; Humans; Janus Kinases; STAT Transcription Fact

2022
Ruxolitinib enhances cytotoxic and apoptotic effects of temozolomide on glioblastoma cells by regulating WNT signaling pathway-related genes.
    Medical oncology (Northwood, London, England), 2022, Dec-02, Volume: 40, Issue:1

    Topics: Antineoplastic Agents; Brain Neoplasms; Glioblastoma; Humans; Janus Kinases; STAT Transcription Fact

2022
Ruxolitinib enhances cytotoxic and apoptotic effects of temozolomide on glioblastoma cells by regulating WNT signaling pathway-related genes.
    Medical oncology (Northwood, London, England), 2022, Dec-02, Volume: 40, Issue:1

    Topics: Antineoplastic Agents; Brain Neoplasms; Glioblastoma; Humans; Janus Kinases; STAT Transcription Fact

2022
Ruxolitinib enhances cytotoxic and apoptotic effects of temozolomide on glioblastoma cells by regulating WNT signaling pathway-related genes.
    Medical oncology (Northwood, London, England), 2022, Dec-02, Volume: 40, Issue:1

    Topics: Antineoplastic Agents; Brain Neoplasms; Glioblastoma; Humans; Janus Kinases; STAT Transcription Fact

2022
Ruxolitinib enhances cytotoxic and apoptotic effects of temozolomide on glioblastoma cells by regulating WNT signaling pathway-related genes.
    Medical oncology (Northwood, London, England), 2022, Dec-02, Volume: 40, Issue:1

    Topics: Antineoplastic Agents; Brain Neoplasms; Glioblastoma; Humans; Janus Kinases; STAT Transcription Fact

2022
Ruxolitinib enhances cytotoxic and apoptotic effects of temozolomide on glioblastoma cells by regulating WNT signaling pathway-related genes.
    Medical oncology (Northwood, London, England), 2022, Dec-02, Volume: 40, Issue:1

    Topics: Antineoplastic Agents; Brain Neoplasms; Glioblastoma; Humans; Janus Kinases; STAT Transcription Fact

2022
Ruxolitinib enhances cytotoxic and apoptotic effects of temozolomide on glioblastoma cells by regulating WNT signaling pathway-related genes.
    Medical oncology (Northwood, London, England), 2022, Dec-02, Volume: 40, Issue:1

    Topics: Antineoplastic Agents; Brain Neoplasms; Glioblastoma; Humans; Janus Kinases; STAT Transcription Fact

2022
Ruxolitinib enhances cytotoxic and apoptotic effects of temozolomide on glioblastoma cells by regulating WNT signaling pathway-related genes.
    Medical oncology (Northwood, London, England), 2022, Dec-02, Volume: 40, Issue:1

    Topics: Antineoplastic Agents; Brain Neoplasms; Glioblastoma; Humans; Janus Kinases; STAT Transcription Fact

2022
Ruxolitinib enhances cytotoxic and apoptotic effects of temozolomide on glioblastoma cells by regulating WNT signaling pathway-related genes.
    Medical oncology (Northwood, London, England), 2022, Dec-02, Volume: 40, Issue:1

    Topics: Antineoplastic Agents; Brain Neoplasms; Glioblastoma; Humans; Janus Kinases; STAT Transcription Fact

2022
Ruxolitinib enhances cytotoxic and apoptotic effects of temozolomide on glioblastoma cells by regulating WNT signaling pathway-related genes.
    Medical oncology (Northwood, London, England), 2022, Dec-02, Volume: 40, Issue:1

    Topics: Antineoplastic Agents; Brain Neoplasms; Glioblastoma; Humans; Janus Kinases; STAT Transcription Fact

2022
Ruxolitinib enhances cytotoxic and apoptotic effects of temozolomide on glioblastoma cells by regulating WNT signaling pathway-related genes.
    Medical oncology (Northwood, London, England), 2022, Dec-02, Volume: 40, Issue:1

    Topics: Antineoplastic Agents; Brain Neoplasms; Glioblastoma; Humans; Janus Kinases; STAT Transcription Fact

2022
Ruxolitinib enhances cytotoxic and apoptotic effects of temozolomide on glioblastoma cells by regulating WNT signaling pathway-related genes.
    Medical oncology (Northwood, London, England), 2022, Dec-02, Volume: 40, Issue:1

    Topics: Antineoplastic Agents; Brain Neoplasms; Glioblastoma; Humans; Janus Kinases; STAT Transcription Fact

2022
Implication of lncRNA ZBED3-AS1 downregulation in acquired resistance to Temozolomide and glycolysis in glioblastoma.
    European journal of pharmacology, 2023, Jan-05, Volume: 938

    Topics: Animals; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; DNA-Binding Proteins; Down-Regulatio

2023
Implication of lncRNA ZBED3-AS1 downregulation in acquired resistance to Temozolomide and glycolysis in glioblastoma.
    European journal of pharmacology, 2023, Jan-05, Volume: 938

    Topics: Animals; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; DNA-Binding Proteins; Down-Regulatio

2023
Implication of lncRNA ZBED3-AS1 downregulation in acquired resistance to Temozolomide and glycolysis in glioblastoma.
    European journal of pharmacology, 2023, Jan-05, Volume: 938

    Topics: Animals; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; DNA-Binding Proteins; Down-Regulatio

2023
Implication of lncRNA ZBED3-AS1 downregulation in acquired resistance to Temozolomide and glycolysis in glioblastoma.
    European journal of pharmacology, 2023, Jan-05, Volume: 938

    Topics: Animals; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; DNA-Binding Proteins; Down-Regulatio

2023
Implication of lncRNA ZBED3-AS1 downregulation in acquired resistance to Temozolomide and glycolysis in glioblastoma.
    European journal of pharmacology, 2023, Jan-05, Volume: 938

    Topics: Animals; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; DNA-Binding Proteins; Down-Regulatio

2023
Implication of lncRNA ZBED3-AS1 downregulation in acquired resistance to Temozolomide and glycolysis in glioblastoma.
    European journal of pharmacology, 2023, Jan-05, Volume: 938

    Topics: Animals; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; DNA-Binding Proteins; Down-Regulatio

2023
Implication of lncRNA ZBED3-AS1 downregulation in acquired resistance to Temozolomide and glycolysis in glioblastoma.
    European journal of pharmacology, 2023, Jan-05, Volume: 938

    Topics: Animals; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; DNA-Binding Proteins; Down-Regulatio

2023
Implication of lncRNA ZBED3-AS1 downregulation in acquired resistance to Temozolomide and glycolysis in glioblastoma.
    European journal of pharmacology, 2023, Jan-05, Volume: 938

    Topics: Animals; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; DNA-Binding Proteins; Down-Regulatio

2023
Implication of lncRNA ZBED3-AS1 downregulation in acquired resistance to Temozolomide and glycolysis in glioblastoma.
    European journal of pharmacology, 2023, Jan-05, Volume: 938

    Topics: Animals; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; DNA-Binding Proteins; Down-Regulatio

2023
Implication of lncRNA ZBED3-AS1 downregulation in acquired resistance to Temozolomide and glycolysis in glioblastoma.
    European journal of pharmacology, 2023, Jan-05, Volume: 938

    Topics: Animals; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; DNA-Binding Proteins; Down-Regulatio

2023
Implication of lncRNA ZBED3-AS1 downregulation in acquired resistance to Temozolomide and glycolysis in glioblastoma.
    European journal of pharmacology, 2023, Jan-05, Volume: 938

    Topics: Animals; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; DNA-Binding Proteins; Down-Regulatio

2023
Implication of lncRNA ZBED3-AS1 downregulation in acquired resistance to Temozolomide and glycolysis in glioblastoma.
    European journal of pharmacology, 2023, Jan-05, Volume: 938

    Topics: Animals; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; DNA-Binding Proteins; Down-Regulatio

2023
A Novel Tumor-Promoting Role for Nuclear Factor IX in Glioblastoma Is Mediated through Transcriptional Activation of GINS1.
    Molecular cancer research : MCR, 2023, 03-01, Volume: 21, Issue:3

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; DNA-Bindin

2023
A Novel Tumor-Promoting Role for Nuclear Factor IX in Glioblastoma Is Mediated through Transcriptional Activation of GINS1.
    Molecular cancer research : MCR, 2023, 03-01, Volume: 21, Issue:3

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; DNA-Bindin

2023
A Novel Tumor-Promoting Role for Nuclear Factor IX in Glioblastoma Is Mediated through Transcriptional Activation of GINS1.
    Molecular cancer research : MCR, 2023, 03-01, Volume: 21, Issue:3

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; DNA-Bindin

2023
A Novel Tumor-Promoting Role for Nuclear Factor IX in Glioblastoma Is Mediated through Transcriptional Activation of GINS1.
    Molecular cancer research : MCR, 2023, 03-01, Volume: 21, Issue:3

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; DNA-Bindin

2023
A Novel Tumor-Promoting Role for Nuclear Factor IX in Glioblastoma Is Mediated through Transcriptional Activation of GINS1.
    Molecular cancer research : MCR, 2023, 03-01, Volume: 21, Issue:3

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; DNA-Bindin

2023
A Novel Tumor-Promoting Role for Nuclear Factor IX in Glioblastoma Is Mediated through Transcriptional Activation of GINS1.
    Molecular cancer research : MCR, 2023, 03-01, Volume: 21, Issue:3

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; DNA-Bindin

2023
A Novel Tumor-Promoting Role for Nuclear Factor IX in Glioblastoma Is Mediated through Transcriptional Activation of GINS1.
    Molecular cancer research : MCR, 2023, 03-01, Volume: 21, Issue:3

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; DNA-Bindin

2023
A Novel Tumor-Promoting Role for Nuclear Factor IX in Glioblastoma Is Mediated through Transcriptional Activation of GINS1.
    Molecular cancer research : MCR, 2023, 03-01, Volume: 21, Issue:3

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; DNA-Bindin

2023
A Novel Tumor-Promoting Role for Nuclear Factor IX in Glioblastoma Is Mediated through Transcriptional Activation of GINS1.
    Molecular cancer research : MCR, 2023, 03-01, Volume: 21, Issue:3

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; DNA-Bindin

2023
A Novel Tumor-Promoting Role for Nuclear Factor IX in Glioblastoma Is Mediated through Transcriptional Activation of GINS1.
    Molecular cancer research : MCR, 2023, 03-01, Volume: 21, Issue:3

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; DNA-Bindin

2023
A Novel Tumor-Promoting Role for Nuclear Factor IX in Glioblastoma Is Mediated through Transcriptional Activation of GINS1.
    Molecular cancer research : MCR, 2023, 03-01, Volume: 21, Issue:3

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; DNA-Bindin

2023
A Novel Tumor-Promoting Role for Nuclear Factor IX in Glioblastoma Is Mediated through Transcriptional Activation of GINS1.
    Molecular cancer research : MCR, 2023, 03-01, Volume: 21, Issue:3

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; DNA-Bindin

2023
Normofractionated irradiation and not temozolomide modulates the immunogenic and oncogenic phenotype of human glioblastoma cell lines.
    Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 2023, Volume: 199, Issue:12

    Topics: B7-H1 Antigen; Brain Neoplasms; Cell Line, Tumor; ErbB Receptors; Glioblastoma; Humans; Temozolomide

2023
Normofractionated irradiation and not temozolomide modulates the immunogenic and oncogenic phenotype of human glioblastoma cell lines.
    Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 2023, Volume: 199, Issue:12

    Topics: B7-H1 Antigen; Brain Neoplasms; Cell Line, Tumor; ErbB Receptors; Glioblastoma; Humans; Temozolomide

2023
Normofractionated irradiation and not temozolomide modulates the immunogenic and oncogenic phenotype of human glioblastoma cell lines.
    Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 2023, Volume: 199, Issue:12

    Topics: B7-H1 Antigen; Brain Neoplasms; Cell Line, Tumor; ErbB Receptors; Glioblastoma; Humans; Temozolomide

2023
Normofractionated irradiation and not temozolomide modulates the immunogenic and oncogenic phenotype of human glioblastoma cell lines.
    Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 2023, Volume: 199, Issue:12

    Topics: B7-H1 Antigen; Brain Neoplasms; Cell Line, Tumor; ErbB Receptors; Glioblastoma; Humans; Temozolomide

2023
Normofractionated irradiation and not temozolomide modulates the immunogenic and oncogenic phenotype of human glioblastoma cell lines.
    Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 2023, Volume: 199, Issue:12

    Topics: B7-H1 Antigen; Brain Neoplasms; Cell Line, Tumor; ErbB Receptors; Glioblastoma; Humans; Temozolomide

2023
Normofractionated irradiation and not temozolomide modulates the immunogenic and oncogenic phenotype of human glioblastoma cell lines.
    Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 2023, Volume: 199, Issue:12

    Topics: B7-H1 Antigen; Brain Neoplasms; Cell Line, Tumor; ErbB Receptors; Glioblastoma; Humans; Temozolomide

2023
Normofractionated irradiation and not temozolomide modulates the immunogenic and oncogenic phenotype of human glioblastoma cell lines.
    Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 2023, Volume: 199, Issue:12

    Topics: B7-H1 Antigen; Brain Neoplasms; Cell Line, Tumor; ErbB Receptors; Glioblastoma; Humans; Temozolomide

2023
Normofractionated irradiation and not temozolomide modulates the immunogenic and oncogenic phenotype of human glioblastoma cell lines.
    Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 2023, Volume: 199, Issue:12

    Topics: B7-H1 Antigen; Brain Neoplasms; Cell Line, Tumor; ErbB Receptors; Glioblastoma; Humans; Temozolomide

2023
Normofractionated irradiation and not temozolomide modulates the immunogenic and oncogenic phenotype of human glioblastoma cell lines.
    Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 2023, Volume: 199, Issue:12

    Topics: B7-H1 Antigen; Brain Neoplasms; Cell Line, Tumor; ErbB Receptors; Glioblastoma; Humans; Temozolomide

2023
Normofractionated irradiation and not temozolomide modulates the immunogenic and oncogenic phenotype of human glioblastoma cell lines.
    Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 2023, Volume: 199, Issue:12

    Topics: B7-H1 Antigen; Brain Neoplasms; Cell Line, Tumor; ErbB Receptors; Glioblastoma; Humans; Temozolomide

2023
Normofractionated irradiation and not temozolomide modulates the immunogenic and oncogenic phenotype of human glioblastoma cell lines.
    Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 2023, Volume: 199, Issue:12

    Topics: B7-H1 Antigen; Brain Neoplasms; Cell Line, Tumor; ErbB Receptors; Glioblastoma; Humans; Temozolomide

2023
Normofractionated irradiation and not temozolomide modulates the immunogenic and oncogenic phenotype of human glioblastoma cell lines.
    Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 2023, Volume: 199, Issue:12

    Topics: B7-H1 Antigen; Brain Neoplasms; Cell Line, Tumor; ErbB Receptors; Glioblastoma; Humans; Temozolomide

2023
Ultrasound-excited temozolomide sonosensitization induces necroptosis in glioblastoma.
    Cancer letters, 2023, 02-01, Volume: 554

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; Gli

2023
Ultrasound-excited temozolomide sonosensitization induces necroptosis in glioblastoma.
    Cancer letters, 2023, 02-01, Volume: 554

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; Gli

2023
Ultrasound-excited temozolomide sonosensitization induces necroptosis in glioblastoma.
    Cancer letters, 2023, 02-01, Volume: 554

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; Gli

2023
Ultrasound-excited temozolomide sonosensitization induces necroptosis in glioblastoma.
    Cancer letters, 2023, 02-01, Volume: 554

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; Gli

2023
Ultrasound-excited temozolomide sonosensitization induces necroptosis in glioblastoma.
    Cancer letters, 2023, 02-01, Volume: 554

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; Gli

2023
Ultrasound-excited temozolomide sonosensitization induces necroptosis in glioblastoma.
    Cancer letters, 2023, 02-01, Volume: 554

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; Gli

2023
Ultrasound-excited temozolomide sonosensitization induces necroptosis in glioblastoma.
    Cancer letters, 2023, 02-01, Volume: 554

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; Gli

2023
Ultrasound-excited temozolomide sonosensitization induces necroptosis in glioblastoma.
    Cancer letters, 2023, 02-01, Volume: 554

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; Gli

2023
Ultrasound-excited temozolomide sonosensitization induces necroptosis in glioblastoma.
    Cancer letters, 2023, 02-01, Volume: 554

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; Gli

2023
Ultrasound-excited temozolomide sonosensitization induces necroptosis in glioblastoma.
    Cancer letters, 2023, 02-01, Volume: 554

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; Gli

2023
Ultrasound-excited temozolomide sonosensitization induces necroptosis in glioblastoma.
    Cancer letters, 2023, 02-01, Volume: 554

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; Gli

2023
Ultrasound-excited temozolomide sonosensitization induces necroptosis in glioblastoma.
    Cancer letters, 2023, 02-01, Volume: 554

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; Gli

2023
CD147 Protein Expression and Temozolomide Resistance in Glioma Cells: An Ex vivo and In vivo Study.
    Cellular and molecular biology (Noisy-le-Grand, France), 2022, Jul-31, Volume: 68, Issue:7

    Topics: Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Drug Resistance, Neoplasm; Gene Ex

2022
CD147 Protein Expression and Temozolomide Resistance in Glioma Cells: An Ex vivo and In vivo Study.
    Cellular and molecular biology (Noisy-le-Grand, France), 2022, Jul-31, Volume: 68, Issue:7

    Topics: Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Drug Resistance, Neoplasm; Gene Ex

2022
CD147 Protein Expression and Temozolomide Resistance in Glioma Cells: An Ex vivo and In vivo Study.
    Cellular and molecular biology (Noisy-le-Grand, France), 2022, Jul-31, Volume: 68, Issue:7

    Topics: Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Drug Resistance, Neoplasm; Gene Ex

2022
CD147 Protein Expression and Temozolomide Resistance in Glioma Cells: An Ex vivo and In vivo Study.
    Cellular and molecular biology (Noisy-le-Grand, France), 2022, Jul-31, Volume: 68, Issue:7

    Topics: Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Drug Resistance, Neoplasm; Gene Ex

2022
CD147 Protein Expression and Temozolomide Resistance in Glioma Cells: An Ex vivo and In vivo Study.
    Cellular and molecular biology (Noisy-le-Grand, France), 2022, Jul-31, Volume: 68, Issue:7

    Topics: Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Drug Resistance, Neoplasm; Gene Ex

2022
CD147 Protein Expression and Temozolomide Resistance in Glioma Cells: An Ex vivo and In vivo Study.
    Cellular and molecular biology (Noisy-le-Grand, France), 2022, Jul-31, Volume: 68, Issue:7

    Topics: Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Drug Resistance, Neoplasm; Gene Ex

2022
CD147 Protein Expression and Temozolomide Resistance in Glioma Cells: An Ex vivo and In vivo Study.
    Cellular and molecular biology (Noisy-le-Grand, France), 2022, Jul-31, Volume: 68, Issue:7

    Topics: Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Drug Resistance, Neoplasm; Gene Ex

2022
CD147 Protein Expression and Temozolomide Resistance in Glioma Cells: An Ex vivo and In vivo Study.
    Cellular and molecular biology (Noisy-le-Grand, France), 2022, Jul-31, Volume: 68, Issue:7

    Topics: Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Drug Resistance, Neoplasm; Gene Ex

2022
CD147 Protein Expression and Temozolomide Resistance in Glioma Cells: An Ex vivo and In vivo Study.
    Cellular and molecular biology (Noisy-le-Grand, France), 2022, Jul-31, Volume: 68, Issue:7

    Topics: Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Drug Resistance, Neoplasm; Gene Ex

2022
CD147 Protein Expression and Temozolomide Resistance in Glioma Cells: An Ex vivo and In vivo Study.
    Cellular and molecular biology (Noisy-le-Grand, France), 2022, Jul-31, Volume: 68, Issue:7

    Topics: Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Drug Resistance, Neoplasm; Gene Ex

2022
CD147 Protein Expression and Temozolomide Resistance in Glioma Cells: An Ex vivo and In vivo Study.
    Cellular and molecular biology (Noisy-le-Grand, France), 2022, Jul-31, Volume: 68, Issue:7

    Topics: Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Drug Resistance, Neoplasm; Gene Ex

2022
CD147 Protein Expression and Temozolomide Resistance in Glioma Cells: An Ex vivo and In vivo Study.
    Cellular and molecular biology (Noisy-le-Grand, France), 2022, Jul-31, Volume: 68, Issue:7

    Topics: Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Drug Resistance, Neoplasm; Gene Ex

2022
TRPML2 Mucolipin Channels Drive the Response of Glioma Stem Cells to Temozolomide and Affect the Overall Survival in Glioblastoma Patients.
    International journal of molecular sciences, 2022, Dec-05, Volume: 23, Issue:23

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; Gli

2022
TRPML2 Mucolipin Channels Drive the Response of Glioma Stem Cells to Temozolomide and Affect the Overall Survival in Glioblastoma Patients.
    International journal of molecular sciences, 2022, Dec-05, Volume: 23, Issue:23

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; Gli

2022
TRPML2 Mucolipin Channels Drive the Response of Glioma Stem Cells to Temozolomide and Affect the Overall Survival in Glioblastoma Patients.
    International journal of molecular sciences, 2022, Dec-05, Volume: 23, Issue:23

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; Gli

2022
TRPML2 Mucolipin Channels Drive the Response of Glioma Stem Cells to Temozolomide and Affect the Overall Survival in Glioblastoma Patients.
    International journal of molecular sciences, 2022, Dec-05, Volume: 23, Issue:23

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; Gli

2022
TRPML2 Mucolipin Channels Drive the Response of Glioma Stem Cells to Temozolomide and Affect the Overall Survival in Glioblastoma Patients.
    International journal of molecular sciences, 2022, Dec-05, Volume: 23, Issue:23

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; Gli

2022
TRPML2 Mucolipin Channels Drive the Response of Glioma Stem Cells to Temozolomide and Affect the Overall Survival in Glioblastoma Patients.
    International journal of molecular sciences, 2022, Dec-05, Volume: 23, Issue:23

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; Gli

2022
TRPML2 Mucolipin Channels Drive the Response of Glioma Stem Cells to Temozolomide and Affect the Overall Survival in Glioblastoma Patients.
    International journal of molecular sciences, 2022, Dec-05, Volume: 23, Issue:23

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; Gli

2022
TRPML2 Mucolipin Channels Drive the Response of Glioma Stem Cells to Temozolomide and Affect the Overall Survival in Glioblastoma Patients.
    International journal of molecular sciences, 2022, Dec-05, Volume: 23, Issue:23

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; Gli

2022
TRPML2 Mucolipin Channels Drive the Response of Glioma Stem Cells to Temozolomide and Affect the Overall Survival in Glioblastoma Patients.
    International journal of molecular sciences, 2022, Dec-05, Volume: 23, Issue:23

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; Gli

2022
TRPML2 Mucolipin Channels Drive the Response of Glioma Stem Cells to Temozolomide and Affect the Overall Survival in Glioblastoma Patients.
    International journal of molecular sciences, 2022, Dec-05, Volume: 23, Issue:23

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; Gli

2022
TRPML2 Mucolipin Channels Drive the Response of Glioma Stem Cells to Temozolomide and Affect the Overall Survival in Glioblastoma Patients.
    International journal of molecular sciences, 2022, Dec-05, Volume: 23, Issue:23

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; Gli

2022
TRPML2 Mucolipin Channels Drive the Response of Glioma Stem Cells to Temozolomide and Affect the Overall Survival in Glioblastoma Patients.
    International journal of molecular sciences, 2022, Dec-05, Volume: 23, Issue:23

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; Gli

2022
Isoginkgetin-A Natural Compound to Control U87MG Glioblastoma Cell Growth and Migration Activating Apoptosis and Autophagy.
    Molecules (Basel, Switzerland), 2022, Nov-29, Volume: 27, Issue:23

    Topics: Antineoplastic Agents, Alkylating; Apoptosis; Autophagy; Brain Neoplasms; Cell Cycle; Cell Line, Tum

2022
Isoginkgetin-A Natural Compound to Control U87MG Glioblastoma Cell Growth and Migration Activating Apoptosis and Autophagy.
    Molecules (Basel, Switzerland), 2022, Nov-29, Volume: 27, Issue:23

    Topics: Antineoplastic Agents, Alkylating; Apoptosis; Autophagy; Brain Neoplasms; Cell Cycle; Cell Line, Tum

2022
Isoginkgetin-A Natural Compound to Control U87MG Glioblastoma Cell Growth and Migration Activating Apoptosis and Autophagy.
    Molecules (Basel, Switzerland), 2022, Nov-29, Volume: 27, Issue:23

    Topics: Antineoplastic Agents, Alkylating; Apoptosis; Autophagy; Brain Neoplasms; Cell Cycle; Cell Line, Tum

2022
Isoginkgetin-A Natural Compound to Control U87MG Glioblastoma Cell Growth and Migration Activating Apoptosis and Autophagy.
    Molecules (Basel, Switzerland), 2022, Nov-29, Volume: 27, Issue:23

    Topics: Antineoplastic Agents, Alkylating; Apoptosis; Autophagy; Brain Neoplasms; Cell Cycle; Cell Line, Tum

2022
Isoginkgetin-A Natural Compound to Control U87MG Glioblastoma Cell Growth and Migration Activating Apoptosis and Autophagy.
    Molecules (Basel, Switzerland), 2022, Nov-29, Volume: 27, Issue:23

    Topics: Antineoplastic Agents, Alkylating; Apoptosis; Autophagy; Brain Neoplasms; Cell Cycle; Cell Line, Tum

2022
Isoginkgetin-A Natural Compound to Control U87MG Glioblastoma Cell Growth and Migration Activating Apoptosis and Autophagy.
    Molecules (Basel, Switzerland), 2022, Nov-29, Volume: 27, Issue:23

    Topics: Antineoplastic Agents, Alkylating; Apoptosis; Autophagy; Brain Neoplasms; Cell Cycle; Cell Line, Tum

2022
Isoginkgetin-A Natural Compound to Control U87MG Glioblastoma Cell Growth and Migration Activating Apoptosis and Autophagy.
    Molecules (Basel, Switzerland), 2022, Nov-29, Volume: 27, Issue:23

    Topics: Antineoplastic Agents, Alkylating; Apoptosis; Autophagy; Brain Neoplasms; Cell Cycle; Cell Line, Tum

2022
Isoginkgetin-A Natural Compound to Control U87MG Glioblastoma Cell Growth and Migration Activating Apoptosis and Autophagy.
    Molecules (Basel, Switzerland), 2022, Nov-29, Volume: 27, Issue:23

    Topics: Antineoplastic Agents, Alkylating; Apoptosis; Autophagy; Brain Neoplasms; Cell Cycle; Cell Line, Tum

2022
Isoginkgetin-A Natural Compound to Control U87MG Glioblastoma Cell Growth and Migration Activating Apoptosis and Autophagy.
    Molecules (Basel, Switzerland), 2022, Nov-29, Volume: 27, Issue:23

    Topics: Antineoplastic Agents, Alkylating; Apoptosis; Autophagy; Brain Neoplasms; Cell Cycle; Cell Line, Tum

2022
Isoginkgetin-A Natural Compound to Control U87MG Glioblastoma Cell Growth and Migration Activating Apoptosis and Autophagy.
    Molecules (Basel, Switzerland), 2022, Nov-29, Volume: 27, Issue:23

    Topics: Antineoplastic Agents, Alkylating; Apoptosis; Autophagy; Brain Neoplasms; Cell Cycle; Cell Line, Tum

2022
Isoginkgetin-A Natural Compound to Control U87MG Glioblastoma Cell Growth and Migration Activating Apoptosis and Autophagy.
    Molecules (Basel, Switzerland), 2022, Nov-29, Volume: 27, Issue:23

    Topics: Antineoplastic Agents, Alkylating; Apoptosis; Autophagy; Brain Neoplasms; Cell Cycle; Cell Line, Tum

2022
Isoginkgetin-A Natural Compound to Control U87MG Glioblastoma Cell Growth and Migration Activating Apoptosis and Autophagy.
    Molecules (Basel, Switzerland), 2022, Nov-29, Volume: 27, Issue:23

    Topics: Antineoplastic Agents, Alkylating; Apoptosis; Autophagy; Brain Neoplasms; Cell Cycle; Cell Line, Tum

2022
Supraorbital transciliary approach as primary route to fronto-basal high grade glioma resection with 5-Aminolevulinic Acid use: Technical note.
    Neuro-Chirurgie, 2023, Volume: 69, Issue:1

    Topics: Aminolevulinic Acid; Brain Neoplasms; Glioblastoma; Glioma; Humans; Neoplasm Recurrence, Local; Temo

2023
Supraorbital transciliary approach as primary route to fronto-basal high grade glioma resection with 5-Aminolevulinic Acid use: Technical note.
    Neuro-Chirurgie, 2023, Volume: 69, Issue:1

    Topics: Aminolevulinic Acid; Brain Neoplasms; Glioblastoma; Glioma; Humans; Neoplasm Recurrence, Local; Temo

2023
Supraorbital transciliary approach as primary route to fronto-basal high grade glioma resection with 5-Aminolevulinic Acid use: Technical note.
    Neuro-Chirurgie, 2023, Volume: 69, Issue:1

    Topics: Aminolevulinic Acid; Brain Neoplasms; Glioblastoma; Glioma; Humans; Neoplasm Recurrence, Local; Temo

2023
Supraorbital transciliary approach as primary route to fronto-basal high grade glioma resection with 5-Aminolevulinic Acid use: Technical note.
    Neuro-Chirurgie, 2023, Volume: 69, Issue:1

    Topics: Aminolevulinic Acid; Brain Neoplasms; Glioblastoma; Glioma; Humans; Neoplasm Recurrence, Local; Temo

2023
Supraorbital transciliary approach as primary route to fronto-basal high grade glioma resection with 5-Aminolevulinic Acid use: Technical note.
    Neuro-Chirurgie, 2023, Volume: 69, Issue:1

    Topics: Aminolevulinic Acid; Brain Neoplasms; Glioblastoma; Glioma; Humans; Neoplasm Recurrence, Local; Temo

2023
Supraorbital transciliary approach as primary route to fronto-basal high grade glioma resection with 5-Aminolevulinic Acid use: Technical note.
    Neuro-Chirurgie, 2023, Volume: 69, Issue:1

    Topics: Aminolevulinic Acid; Brain Neoplasms; Glioblastoma; Glioma; Humans; Neoplasm Recurrence, Local; Temo

2023
Supraorbital transciliary approach as primary route to fronto-basal high grade glioma resection with 5-Aminolevulinic Acid use: Technical note.
    Neuro-Chirurgie, 2023, Volume: 69, Issue:1

    Topics: Aminolevulinic Acid; Brain Neoplasms; Glioblastoma; Glioma; Humans; Neoplasm Recurrence, Local; Temo

2023
Supraorbital transciliary approach as primary route to fronto-basal high grade glioma resection with 5-Aminolevulinic Acid use: Technical note.
    Neuro-Chirurgie, 2023, Volume: 69, Issue:1

    Topics: Aminolevulinic Acid; Brain Neoplasms; Glioblastoma; Glioma; Humans; Neoplasm Recurrence, Local; Temo

2023
Supraorbital transciliary approach as primary route to fronto-basal high grade glioma resection with 5-Aminolevulinic Acid use: Technical note.
    Neuro-Chirurgie, 2023, Volume: 69, Issue:1

    Topics: Aminolevulinic Acid; Brain Neoplasms; Glioblastoma; Glioma; Humans; Neoplasm Recurrence, Local; Temo

2023
Supraorbital transciliary approach as primary route to fronto-basal high grade glioma resection with 5-Aminolevulinic Acid use: Technical note.
    Neuro-Chirurgie, 2023, Volume: 69, Issue:1

    Topics: Aminolevulinic Acid; Brain Neoplasms; Glioblastoma; Glioma; Humans; Neoplasm Recurrence, Local; Temo

2023
Supraorbital transciliary approach as primary route to fronto-basal high grade glioma resection with 5-Aminolevulinic Acid use: Technical note.
    Neuro-Chirurgie, 2023, Volume: 69, Issue:1

    Topics: Aminolevulinic Acid; Brain Neoplasms; Glioblastoma; Glioma; Humans; Neoplasm Recurrence, Local; Temo

2023
Supraorbital transciliary approach as primary route to fronto-basal high grade glioma resection with 5-Aminolevulinic Acid use: Technical note.
    Neuro-Chirurgie, 2023, Volume: 69, Issue:1

    Topics: Aminolevulinic Acid; Brain Neoplasms; Glioblastoma; Glioma; Humans; Neoplasm Recurrence, Local; Temo

2023
Comparative Study of Extremely Low-Frequency Electromagnetic Field, Radiation, and Temozolomide Administration in Spheroid and Monolayer Forms of the Glioblastoma Cell Line (T98).
    Current radiopharmaceuticals, 2023, Volume: 16, Issue:2

    Topics: Apoptosis; Brain Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; Electromagnetic Fields; Gli

2023
Comparative Study of Extremely Low-Frequency Electromagnetic Field, Radiation, and Temozolomide Administration in Spheroid and Monolayer Forms of the Glioblastoma Cell Line (T98).
    Current radiopharmaceuticals, 2023, Volume: 16, Issue:2

    Topics: Apoptosis; Brain Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; Electromagnetic Fields; Gli

2023
Comparative Study of Extremely Low-Frequency Electromagnetic Field, Radiation, and Temozolomide Administration in Spheroid and Monolayer Forms of the Glioblastoma Cell Line (T98).
    Current radiopharmaceuticals, 2023, Volume: 16, Issue:2

    Topics: Apoptosis; Brain Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; Electromagnetic Fields; Gli

2023
Comparative Study of Extremely Low-Frequency Electromagnetic Field, Radiation, and Temozolomide Administration in Spheroid and Monolayer Forms of the Glioblastoma Cell Line (T98).
    Current radiopharmaceuticals, 2023, Volume: 16, Issue:2

    Topics: Apoptosis; Brain Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; Electromagnetic Fields; Gli

2023
Comparative Study of Extremely Low-Frequency Electromagnetic Field, Radiation, and Temozolomide Administration in Spheroid and Monolayer Forms of the Glioblastoma Cell Line (T98).
    Current radiopharmaceuticals, 2023, Volume: 16, Issue:2

    Topics: Apoptosis; Brain Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; Electromagnetic Fields; Gli

2023
Comparative Study of Extremely Low-Frequency Electromagnetic Field, Radiation, and Temozolomide Administration in Spheroid and Monolayer Forms of the Glioblastoma Cell Line (T98).
    Current radiopharmaceuticals, 2023, Volume: 16, Issue:2

    Topics: Apoptosis; Brain Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; Electromagnetic Fields; Gli

2023
Comparative Study of Extremely Low-Frequency Electromagnetic Field, Radiation, and Temozolomide Administration in Spheroid and Monolayer Forms of the Glioblastoma Cell Line (T98).
    Current radiopharmaceuticals, 2023, Volume: 16, Issue:2

    Topics: Apoptosis; Brain Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; Electromagnetic Fields; Gli

2023
Comparative Study of Extremely Low-Frequency Electromagnetic Field, Radiation, and Temozolomide Administration in Spheroid and Monolayer Forms of the Glioblastoma Cell Line (T98).
    Current radiopharmaceuticals, 2023, Volume: 16, Issue:2

    Topics: Apoptosis; Brain Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; Electromagnetic Fields; Gli

2023
Comparative Study of Extremely Low-Frequency Electromagnetic Field, Radiation, and Temozolomide Administration in Spheroid and Monolayer Forms of the Glioblastoma Cell Line (T98).
    Current radiopharmaceuticals, 2023, Volume: 16, Issue:2

    Topics: Apoptosis; Brain Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; Electromagnetic Fields; Gli

2023
Comparative Study of Extremely Low-Frequency Electromagnetic Field, Radiation, and Temozolomide Administration in Spheroid and Monolayer Forms of the Glioblastoma Cell Line (T98).
    Current radiopharmaceuticals, 2023, Volume: 16, Issue:2

    Topics: Apoptosis; Brain Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; Electromagnetic Fields; Gli

2023
Comparative Study of Extremely Low-Frequency Electromagnetic Field, Radiation, and Temozolomide Administration in Spheroid and Monolayer Forms of the Glioblastoma Cell Line (T98).
    Current radiopharmaceuticals, 2023, Volume: 16, Issue:2

    Topics: Apoptosis; Brain Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; Electromagnetic Fields; Gli

2023
Comparative Study of Extremely Low-Frequency Electromagnetic Field, Radiation, and Temozolomide Administration in Spheroid and Monolayer Forms of the Glioblastoma Cell Line (T98).
    Current radiopharmaceuticals, 2023, Volume: 16, Issue:2

    Topics: Apoptosis; Brain Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; Electromagnetic Fields; Gli

2023
MUC1 promotes glioblastoma progression and TMZ resistance by stabilizing EGFRvIII.
    Pharmacological research, 2023, Volume: 187

    Topics: Brain Neoplasms; Cell Line, Tumor; Glioblastoma; Glioma; Humans; Mucin-1; NF-kappa B; Temozolomide

2023
MUC1 promotes glioblastoma progression and TMZ resistance by stabilizing EGFRvIII.
    Pharmacological research, 2023, Volume: 187

    Topics: Brain Neoplasms; Cell Line, Tumor; Glioblastoma; Glioma; Humans; Mucin-1; NF-kappa B; Temozolomide

2023
MUC1 promotes glioblastoma progression and TMZ resistance by stabilizing EGFRvIII.
    Pharmacological research, 2023, Volume: 187

    Topics: Brain Neoplasms; Cell Line, Tumor; Glioblastoma; Glioma; Humans; Mucin-1; NF-kappa B; Temozolomide

2023
MUC1 promotes glioblastoma progression and TMZ resistance by stabilizing EGFRvIII.
    Pharmacological research, 2023, Volume: 187

    Topics: Brain Neoplasms; Cell Line, Tumor; Glioblastoma; Glioma; Humans; Mucin-1; NF-kappa B; Temozolomide

2023
MUC1 promotes glioblastoma progression and TMZ resistance by stabilizing EGFRvIII.
    Pharmacological research, 2023, Volume: 187

    Topics: Brain Neoplasms; Cell Line, Tumor; Glioblastoma; Glioma; Humans; Mucin-1; NF-kappa B; Temozolomide

2023
MUC1 promotes glioblastoma progression and TMZ resistance by stabilizing EGFRvIII.
    Pharmacological research, 2023, Volume: 187

    Topics: Brain Neoplasms; Cell Line, Tumor; Glioblastoma; Glioma; Humans; Mucin-1; NF-kappa B; Temozolomide

2023
MUC1 promotes glioblastoma progression and TMZ resistance by stabilizing EGFRvIII.
    Pharmacological research, 2023, Volume: 187

    Topics: Brain Neoplasms; Cell Line, Tumor; Glioblastoma; Glioma; Humans; Mucin-1; NF-kappa B; Temozolomide

2023
MUC1 promotes glioblastoma progression and TMZ resistance by stabilizing EGFRvIII.
    Pharmacological research, 2023, Volume: 187

    Topics: Brain Neoplasms; Cell Line, Tumor; Glioblastoma; Glioma; Humans; Mucin-1; NF-kappa B; Temozolomide

2023
MUC1 promotes glioblastoma progression and TMZ resistance by stabilizing EGFRvIII.
    Pharmacological research, 2023, Volume: 187

    Topics: Brain Neoplasms; Cell Line, Tumor; Glioblastoma; Glioma; Humans; Mucin-1; NF-kappa B; Temozolomide

2023
MUC1 promotes glioblastoma progression and TMZ resistance by stabilizing EGFRvIII.
    Pharmacological research, 2023, Volume: 187

    Topics: Brain Neoplasms; Cell Line, Tumor; Glioblastoma; Glioma; Humans; Mucin-1; NF-kappa B; Temozolomide

2023
MUC1 promotes glioblastoma progression and TMZ resistance by stabilizing EGFRvIII.
    Pharmacological research, 2023, Volume: 187

    Topics: Brain Neoplasms; Cell Line, Tumor; Glioblastoma; Glioma; Humans; Mucin-1; NF-kappa B; Temozolomide

2023
MUC1 promotes glioblastoma progression and TMZ resistance by stabilizing EGFRvIII.
    Pharmacological research, 2023, Volume: 187

    Topics: Brain Neoplasms; Cell Line, Tumor; Glioblastoma; Glioma; Humans; Mucin-1; NF-kappa B; Temozolomide

2023
EZH2 interacts with HP1BP3 to epigenetically activate WNT7B that promotes temozolomide resistance in glioblastoma.
    Oncogene, 2023, Volume: 42, Issue:6

    Topics: Brain Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; Enhancer of Zeste Homolog 2 Protein; G

2023
EZH2 interacts with HP1BP3 to epigenetically activate WNT7B that promotes temozolomide resistance in glioblastoma.
    Oncogene, 2023, Volume: 42, Issue:6

    Topics: Brain Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; Enhancer of Zeste Homolog 2 Protein; G

2023
EZH2 interacts with HP1BP3 to epigenetically activate WNT7B that promotes temozolomide resistance in glioblastoma.
    Oncogene, 2023, Volume: 42, Issue:6

    Topics: Brain Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; Enhancer of Zeste Homolog 2 Protein; G

2023
EZH2 interacts with HP1BP3 to epigenetically activate WNT7B that promotes temozolomide resistance in glioblastoma.
    Oncogene, 2023, Volume: 42, Issue:6

    Topics: Brain Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; Enhancer of Zeste Homolog 2 Protein; G

2023
EZH2 interacts with HP1BP3 to epigenetically activate WNT7B that promotes temozolomide resistance in glioblastoma.
    Oncogene, 2023, Volume: 42, Issue:6

    Topics: Brain Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; Enhancer of Zeste Homolog 2 Protein; G

2023
EZH2 interacts with HP1BP3 to epigenetically activate WNT7B that promotes temozolomide resistance in glioblastoma.
    Oncogene, 2023, Volume: 42, Issue:6

    Topics: Brain Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; Enhancer of Zeste Homolog 2 Protein; G

2023
EZH2 interacts with HP1BP3 to epigenetically activate WNT7B that promotes temozolomide resistance in glioblastoma.
    Oncogene, 2023, Volume: 42, Issue:6

    Topics: Brain Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; Enhancer of Zeste Homolog 2 Protein; G

2023
EZH2 interacts with HP1BP3 to epigenetically activate WNT7B that promotes temozolomide resistance in glioblastoma.
    Oncogene, 2023, Volume: 42, Issue:6

    Topics: Brain Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; Enhancer of Zeste Homolog 2 Protein; G

2023
EZH2 interacts with HP1BP3 to epigenetically activate WNT7B that promotes temozolomide resistance in glioblastoma.
    Oncogene, 2023, Volume: 42, Issue:6

    Topics: Brain Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; Enhancer of Zeste Homolog 2 Protein; G

2023
EZH2 interacts with HP1BP3 to epigenetically activate WNT7B that promotes temozolomide resistance in glioblastoma.
    Oncogene, 2023, Volume: 42, Issue:6

    Topics: Brain Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; Enhancer of Zeste Homolog 2 Protein; G

2023
EZH2 interacts with HP1BP3 to epigenetically activate WNT7B that promotes temozolomide resistance in glioblastoma.
    Oncogene, 2023, Volume: 42, Issue:6

    Topics: Brain Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; Enhancer of Zeste Homolog 2 Protein; G

2023
EZH2 interacts with HP1BP3 to epigenetically activate WNT7B that promotes temozolomide resistance in glioblastoma.
    Oncogene, 2023, Volume: 42, Issue:6

    Topics: Brain Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; Enhancer of Zeste Homolog 2 Protein; G

2023
Role of COL6A2 in malignant progression and temozolomide resistance of glioma.
    Cellular signalling, 2023, Volume: 102

    Topics: Apoptosis; Brain Neoplasms; Cell Line, Tumor; Collagen Type VI; Glioma; Humans; RNA, Messenger; Temo

2023
Role of COL6A2 in malignant progression and temozolomide resistance of glioma.
    Cellular signalling, 2023, Volume: 102

    Topics: Apoptosis; Brain Neoplasms; Cell Line, Tumor; Collagen Type VI; Glioma; Humans; RNA, Messenger; Temo

2023
Role of COL6A2 in malignant progression and temozolomide resistance of glioma.
    Cellular signalling, 2023, Volume: 102

    Topics: Apoptosis; Brain Neoplasms; Cell Line, Tumor; Collagen Type VI; Glioma; Humans; RNA, Messenger; Temo

2023
Role of COL6A2 in malignant progression and temozolomide resistance of glioma.
    Cellular signalling, 2023, Volume: 102

    Topics: Apoptosis; Brain Neoplasms; Cell Line, Tumor; Collagen Type VI; Glioma; Humans; RNA, Messenger; Temo

2023
Role of COL6A2 in malignant progression and temozolomide resistance of glioma.
    Cellular signalling, 2023, Volume: 102

    Topics: Apoptosis; Brain Neoplasms; Cell Line, Tumor; Collagen Type VI; Glioma; Humans; RNA, Messenger; Temo

2023
Role of COL6A2 in malignant progression and temozolomide resistance of glioma.
    Cellular signalling, 2023, Volume: 102

    Topics: Apoptosis; Brain Neoplasms; Cell Line, Tumor; Collagen Type VI; Glioma; Humans; RNA, Messenger; Temo

2023
Role of COL6A2 in malignant progression and temozolomide resistance of glioma.
    Cellular signalling, 2023, Volume: 102

    Topics: Apoptosis; Brain Neoplasms; Cell Line, Tumor; Collagen Type VI; Glioma; Humans; RNA, Messenger; Temo

2023
Role of COL6A2 in malignant progression and temozolomide resistance of glioma.
    Cellular signalling, 2023, Volume: 102

    Topics: Apoptosis; Brain Neoplasms; Cell Line, Tumor; Collagen Type VI; Glioma; Humans; RNA, Messenger; Temo

2023
Role of COL6A2 in malignant progression and temozolomide resistance of glioma.
    Cellular signalling, 2023, Volume: 102

    Topics: Apoptosis; Brain Neoplasms; Cell Line, Tumor; Collagen Type VI; Glioma; Humans; RNA, Messenger; Temo

2023
Role of COL6A2 in malignant progression and temozolomide resistance of glioma.
    Cellular signalling, 2023, Volume: 102

    Topics: Apoptosis; Brain Neoplasms; Cell Line, Tumor; Collagen Type VI; Glioma; Humans; RNA, Messenger; Temo

2023
Role of COL6A2 in malignant progression and temozolomide resistance of glioma.
    Cellular signalling, 2023, Volume: 102

    Topics: Apoptosis; Brain Neoplasms; Cell Line, Tumor; Collagen Type VI; Glioma; Humans; RNA, Messenger; Temo

2023
Role of COL6A2 in malignant progression and temozolomide resistance of glioma.
    Cellular signalling, 2023, Volume: 102

    Topics: Apoptosis; Brain Neoplasms; Cell Line, Tumor; Collagen Type VI; Glioma; Humans; RNA, Messenger; Temo

2023
SLC11A1 as a stratification indicator for immunotherapy or chemotherapy in patients with glioma.
    Frontiers in immunology, 2022, Volume: 13

    Topics: Brain Neoplasms; China; Glioma; Humans; Immunotherapy; Temozolomide

2022
SLC11A1 as a stratification indicator for immunotherapy or chemotherapy in patients with glioma.
    Frontiers in immunology, 2022, Volume: 13

    Topics: Brain Neoplasms; China; Glioma; Humans; Immunotherapy; Temozolomide

2022
SLC11A1 as a stratification indicator for immunotherapy or chemotherapy in patients with glioma.
    Frontiers in immunology, 2022, Volume: 13

    Topics: Brain Neoplasms; China; Glioma; Humans; Immunotherapy; Temozolomide

2022
PGAM4 silencing inhibited glycolysis and chemoresistance to temozolomide in glioma cells.
    Cell biology international, 2023, Volume: 47, Issue:4

    Topics: Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Drug Resistance, Neoplasm; Glioma;

2023
PGAM4 silencing inhibited glycolysis and chemoresistance to temozolomide in glioma cells.
    Cell biology international, 2023, Volume: 47, Issue:4

    Topics: Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Drug Resistance, Neoplasm; Glioma;

2023
PGAM4 silencing inhibited glycolysis and chemoresistance to temozolomide in glioma cells.
    Cell biology international, 2023, Volume: 47, Issue:4

    Topics: Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Drug Resistance, Neoplasm; Glioma;

2023
The nanoprodrug of polytemozolomide combines with MGMT siRNA to enhance the effect of temozolomide in glioma.
    Drug delivery, 2023, Volume: 30, Issue:1

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Dacarbazine; Drug Res

2023
The nanoprodrug of polytemozolomide combines with MGMT siRNA to enhance the effect of temozolomide in glioma.
    Drug delivery, 2023, Volume: 30, Issue:1

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Dacarbazine; Drug Res

2023
The nanoprodrug of polytemozolomide combines with MGMT siRNA to enhance the effect of temozolomide in glioma.
    Drug delivery, 2023, Volume: 30, Issue:1

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Dacarbazine; Drug Res

2023
Wnt signaling regulates MFSD2A-dependent drug delivery through endothelial transcytosis in glioma.
    Neuro-oncology, 2023, 06-02, Volume: 25, Issue:6

    Topics: Animals; Brain Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; Endothelial Cells; Glioblasto

2023
Wnt signaling regulates MFSD2A-dependent drug delivery through endothelial transcytosis in glioma.
    Neuro-oncology, 2023, 06-02, Volume: 25, Issue:6

    Topics: Animals; Brain Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; Endothelial Cells; Glioblasto

2023
Wnt signaling regulates MFSD2A-dependent drug delivery through endothelial transcytosis in glioma.
    Neuro-oncology, 2023, 06-02, Volume: 25, Issue:6

    Topics: Animals; Brain Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; Endothelial Cells; Glioblasto

2023
Development of a Personalised Device for Systemic Magnetic Drug Targeting to Brain Tumours.
    Nanotheranostics, 2023, Volume: 7, Issue:1

    Topics: Animals; Brain Neoplasms; Drug Delivery Systems; Humans; Magnetic Phenomena; Magnetics; Mice; Temozo

2023
Development of a Personalised Device for Systemic Magnetic Drug Targeting to Brain Tumours.
    Nanotheranostics, 2023, Volume: 7, Issue:1

    Topics: Animals; Brain Neoplasms; Drug Delivery Systems; Humans; Magnetic Phenomena; Magnetics; Mice; Temozo

2023
Development of a Personalised Device for Systemic Magnetic Drug Targeting to Brain Tumours.
    Nanotheranostics, 2023, Volume: 7, Issue:1

    Topics: Animals; Brain Neoplasms; Drug Delivery Systems; Humans; Magnetic Phenomena; Magnetics; Mice; Temozo

2023
A Comparison of Three Different Deep Learning-Based Models to Predict the MGMT Promoter Methylation Status in Glioblastoma Using Brain MRI.
    Journal of digital imaging, 2023, Volume: 36, Issue:3

    Topics: Adult; Brain; Brain Neoplasms; Deep Learning; DNA Methylation; DNA Modification Methylases; DNA Repa

2023
A Comparison of Three Different Deep Learning-Based Models to Predict the MGMT Promoter Methylation Status in Glioblastoma Using Brain MRI.
    Journal of digital imaging, 2023, Volume: 36, Issue:3

    Topics: Adult; Brain; Brain Neoplasms; Deep Learning; DNA Methylation; DNA Modification Methylases; DNA Repa

2023
A Comparison of Three Different Deep Learning-Based Models to Predict the MGMT Promoter Methylation Status in Glioblastoma Using Brain MRI.
    Journal of digital imaging, 2023, Volume: 36, Issue:3

    Topics: Adult; Brain; Brain Neoplasms; Deep Learning; DNA Methylation; DNA Modification Methylases; DNA Repa

2023
Subclonal evolution and expansion of spatially distinct THY1-positive cells is associated with recurrence in glioblastoma.
    Neoplasia (New York, N.Y.), 2023, Volume: 36

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Drug Resistance, Neop

2023
Subclonal evolution and expansion of spatially distinct THY1-positive cells is associated with recurrence in glioblastoma.
    Neoplasia (New York, N.Y.), 2023, Volume: 36

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Drug Resistance, Neop

2023
Subclonal evolution and expansion of spatially distinct THY1-positive cells is associated with recurrence in glioblastoma.
    Neoplasia (New York, N.Y.), 2023, Volume: 36

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Drug Resistance, Neop

2023
Apatinib combined with temozolomide treatment for pseudoprogression in glioblastoma: A case report.
    Medicine, 2022, Dec-09, Volume: 101, Issue:49

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Glioblastoma; Humans; Male; Middle Aged; Neoplas

2022
Apatinib combined with temozolomide treatment for pseudoprogression in glioblastoma: A case report.
    Medicine, 2022, Dec-09, Volume: 101, Issue:49

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Glioblastoma; Humans; Male; Middle Aged; Neoplas

2022
Apatinib combined with temozolomide treatment for pseudoprogression in glioblastoma: A case report.
    Medicine, 2022, Dec-09, Volume: 101, Issue:49

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Glioblastoma; Humans; Male; Middle Aged; Neoplas

2022
A high-density 3-dimensional culture model of human glioblastoma for rapid screening of therapeutic resistance.
    Biochemical pharmacology, 2023, Volume: 208

    Topics: Antineoplastic Agents; Brain Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; Glioblastoma; H

2023
A high-density 3-dimensional culture model of human glioblastoma for rapid screening of therapeutic resistance.
    Biochemical pharmacology, 2023, Volume: 208

    Topics: Antineoplastic Agents; Brain Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; Glioblastoma; H

2023
A high-density 3-dimensional culture model of human glioblastoma for rapid screening of therapeutic resistance.
    Biochemical pharmacology, 2023, Volume: 208

    Topics: Antineoplastic Agents; Brain Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; Glioblastoma; H

2023
Safety and efficacy of tumour-treating fields (TTFields) therapy for newly diagnosed glioblastoma in Japanese patients using the Novo-TTF System: a prospective post-approval study.
    Japanese journal of clinical oncology, 2023, Apr-29, Volume: 53, Issue:5

    Topics: Adult; Brain Neoplasms; East Asian People; Female; Glioblastoma; Humans; Male; Middle Aged; Prospect

2023
Safety and efficacy of tumour-treating fields (TTFields) therapy for newly diagnosed glioblastoma in Japanese patients using the Novo-TTF System: a prospective post-approval study.
    Japanese journal of clinical oncology, 2023, Apr-29, Volume: 53, Issue:5

    Topics: Adult; Brain Neoplasms; East Asian People; Female; Glioblastoma; Humans; Male; Middle Aged; Prospect

2023
Safety and efficacy of tumour-treating fields (TTFields) therapy for newly diagnosed glioblastoma in Japanese patients using the Novo-TTF System: a prospective post-approval study.
    Japanese journal of clinical oncology, 2023, Apr-29, Volume: 53, Issue:5

    Topics: Adult; Brain Neoplasms; East Asian People; Female; Glioblastoma; Humans; Male; Middle Aged; Prospect

2023
Protein Kinase B (PKB/AKT) Protects IDH-Mutated Glioma from Ferroptosis via Nrf2.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2023, 04-03, Volume: 29, Issue:7

    Topics: Animals; Brain Neoplasms; Cell Line, Tumor; Ferroptosis; Glioma; Humans; Isocitrate Dehydrogenase; M

2023
Protein Kinase B (PKB/AKT) Protects IDH-Mutated Glioma from Ferroptosis via Nrf2.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2023, 04-03, Volume: 29, Issue:7

    Topics: Animals; Brain Neoplasms; Cell Line, Tumor; Ferroptosis; Glioma; Humans; Isocitrate Dehydrogenase; M

2023
Protein Kinase B (PKB/AKT) Protects IDH-Mutated Glioma from Ferroptosis via Nrf2.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2023, 04-03, Volume: 29, Issue:7

    Topics: Animals; Brain Neoplasms; Cell Line, Tumor; Ferroptosis; Glioma; Humans; Isocitrate Dehydrogenase; M

2023
Patterns of failure in glioblastoma multiforme following Standard (60 Gy) or Short course (40 Gy) radiation and concurrent temozolomide.
    Japanese journal of radiology, 2023, Volume: 41, Issue:6

    Topics: Brain Neoplasms; Chemoradiotherapy; Glioblastoma; Humans; Retrospective Studies; Temozolomide; Treat

2023
Patterns of failure in glioblastoma multiforme following Standard (60 Gy) or Short course (40 Gy) radiation and concurrent temozolomide.
    Japanese journal of radiology, 2023, Volume: 41, Issue:6

    Topics: Brain Neoplasms; Chemoradiotherapy; Glioblastoma; Humans; Retrospective Studies; Temozolomide; Treat

2023
Patterns of failure in glioblastoma multiforme following Standard (60 Gy) or Short course (40 Gy) radiation and concurrent temozolomide.
    Japanese journal of radiology, 2023, Volume: 41, Issue:6

    Topics: Brain Neoplasms; Chemoradiotherapy; Glioblastoma; Humans; Retrospective Studies; Temozolomide; Treat

2023
Lysine-specific histone demethylase 1A (KDM1A/LSD1) inhibition attenuates DNA double-strand break repair and augments the efficacy of temozolomide in glioblastoma.
    Neuro-oncology, 2023, Jul-06, Volume: 25, Issue:7

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; DNA; DNA Breaks, Doub

2023
Lysine-specific histone demethylase 1A (KDM1A/LSD1) inhibition attenuates DNA double-strand break repair and augments the efficacy of temozolomide in glioblastoma.
    Neuro-oncology, 2023, Jul-06, Volume: 25, Issue:7

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; DNA; DNA Breaks, Doub

2023
Lysine-specific histone demethylase 1A (KDM1A/LSD1) inhibition attenuates DNA double-strand break repair and augments the efficacy of temozolomide in glioblastoma.
    Neuro-oncology, 2023, Jul-06, Volume: 25, Issue:7

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; DNA; DNA Breaks, Doub

2023
ProNGF Expression and Targeting in Glioblastoma Multiforme.
    International journal of molecular sciences, 2023, Jan-13, Volume: 24, Issue:2

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; Gli

2023
ProNGF Expression and Targeting in Glioblastoma Multiforme.
    International journal of molecular sciences, 2023, Jan-13, Volume: 24, Issue:2

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; Gli

2023
ProNGF Expression and Targeting in Glioblastoma Multiforme.
    International journal of molecular sciences, 2023, Jan-13, Volume: 24, Issue:2

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; Gli

2023
Natural Course and Prognosis of Primary Spinal Glioblastoma: A Nationwide Study.
    Neurology, 2023, 04-04, Volume: 100, Issue:14

    Topics: Adolescent; Adult; Brain Neoplasms; Chemoradiotherapy; Glioblastoma; Humans; Middle Aged; Prognosis;

2023
Natural Course and Prognosis of Primary Spinal Glioblastoma: A Nationwide Study.
    Neurology, 2023, 04-04, Volume: 100, Issue:14

    Topics: Adolescent; Adult; Brain Neoplasms; Chemoradiotherapy; Glioblastoma; Humans; Middle Aged; Prognosis;

2023
Natural Course and Prognosis of Primary Spinal Glioblastoma: A Nationwide Study.
    Neurology, 2023, 04-04, Volume: 100, Issue:14

    Topics: Adolescent; Adult; Brain Neoplasms; Chemoradiotherapy; Glioblastoma; Humans; Middle Aged; Prognosis;

2023
Observation of the delineation of the target volume of radiotherapy in adult-type diffuse gliomas after temozolomide-based chemoradiotherapy: analysis of recurrence patterns and predictive factors.
    Radiation oncology (London, England), 2023, Jan-23, Volume: 18, Issue:1

    Topics: Adult; Brain Neoplasms; Chemoradiotherapy; Glioblastoma; Glioma; Humans; Neoplasm Recurrence, Local;

2023
Observation of the delineation of the target volume of radiotherapy in adult-type diffuse gliomas after temozolomide-based chemoradiotherapy: analysis of recurrence patterns and predictive factors.
    Radiation oncology (London, England), 2023, Jan-23, Volume: 18, Issue:1

    Topics: Adult; Brain Neoplasms; Chemoradiotherapy; Glioblastoma; Glioma; Humans; Neoplasm Recurrence, Local;

2023
Observation of the delineation of the target volume of radiotherapy in adult-type diffuse gliomas after temozolomide-based chemoradiotherapy: analysis of recurrence patterns and predictive factors.
    Radiation oncology (London, England), 2023, Jan-23, Volume: 18, Issue:1

    Topics: Adult; Brain Neoplasms; Chemoradiotherapy; Glioblastoma; Glioma; Humans; Neoplasm Recurrence, Local;

2023
Clinical Outcomes of Moderately Hypofractionated Concurrent Chemoradiotherapy for Newly Diagnosed Glioblastoma.
    Yonsei medical journal, 2023, Volume: 64, Issue:2

    Topics: Brain; Brain Neoplasms; Chemoradiotherapy; Glioblastoma; Humans; Radiation Dose Hypofractionation; T

2023
Clinical Outcomes of Moderately Hypofractionated Concurrent Chemoradiotherapy for Newly Diagnosed Glioblastoma.
    Yonsei medical journal, 2023, Volume: 64, Issue:2

    Topics: Brain; Brain Neoplasms; Chemoradiotherapy; Glioblastoma; Humans; Radiation Dose Hypofractionation; T

2023
Clinical Outcomes of Moderately Hypofractionated Concurrent Chemoradiotherapy for Newly Diagnosed Glioblastoma.
    Yonsei medical journal, 2023, Volume: 64, Issue:2

    Topics: Brain; Brain Neoplasms; Chemoradiotherapy; Glioblastoma; Humans; Radiation Dose Hypofractionation; T

2023
How I treat recurrent pediatric high-grade glioma (pHGG): a Europe-wide survey study.
    Journal of neuro-oncology, 2023, Volume: 161, Issue:3

    Topics: Adolescent; Bevacizumab; Brain Neoplasms; Child; Chronic Disease; Glioma; Humans; Proto-Oncogene Pro

2023
How I treat recurrent pediatric high-grade glioma (pHGG): a Europe-wide survey study.
    Journal of neuro-oncology, 2023, Volume: 161, Issue:3

    Topics: Adolescent; Bevacizumab; Brain Neoplasms; Child; Chronic Disease; Glioma; Humans; Proto-Oncogene Pro

2023
How I treat recurrent pediatric high-grade glioma (pHGG): a Europe-wide survey study.
    Journal of neuro-oncology, 2023, Volume: 161, Issue:3

    Topics: Adolescent; Bevacizumab; Brain Neoplasms; Child; Chronic Disease; Glioma; Humans; Proto-Oncogene Pro

2023
Survival in a consecutive series of 467 glioblastoma patients: Association with prognostic factors and treatment at recurrence at two independent institutions.
    PloS one, 2023, Volume: 18, Issue:2

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; DNA Methylation; DNA Modification Methylases; DN

2023
Survival in a consecutive series of 467 glioblastoma patients: Association with prognostic factors and treatment at recurrence at two independent institutions.
    PloS one, 2023, Volume: 18, Issue:2

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; DNA Methylation; DNA Modification Methylases; DN

2023
Survival in a consecutive series of 467 glioblastoma patients: Association with prognostic factors and treatment at recurrence at two independent institutions.
    PloS one, 2023, Volume: 18, Issue:2

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; DNA Methylation; DNA Modification Methylases; DN

2023
Nasal administration of a temozolomide-loaded thermoresponsive nanoemulsion reduces tumor growth in a preclinical glioblastoma model.
    Journal of controlled release : official journal of the Controlled Release Society, 2023, Volume: 355

    Topics: Administration, Intranasal; Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line,

2023
Nasal administration of a temozolomide-loaded thermoresponsive nanoemulsion reduces tumor growth in a preclinical glioblastoma model.
    Journal of controlled release : official journal of the Controlled Release Society, 2023, Volume: 355

    Topics: Administration, Intranasal; Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line,

2023
Nasal administration of a temozolomide-loaded thermoresponsive nanoemulsion reduces tumor growth in a preclinical glioblastoma model.
    Journal of controlled release : official journal of the Controlled Release Society, 2023, Volume: 355

    Topics: Administration, Intranasal; Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line,

2023
Impact of Extended Adjuvant Temozolamide Beyond 6 Months in the Management of Glioblastoma Patients.
    American journal of clinical oncology, 2023, 03-01, Volume: 46, Issue:3

    Topics: Adjuvants, Immunologic; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant;

2023
Impact of Extended Adjuvant Temozolamide Beyond 6 Months in the Management of Glioblastoma Patients.
    American journal of clinical oncology, 2023, 03-01, Volume: 46, Issue:3

    Topics: Adjuvants, Immunologic; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant;

2023
Impact of Extended Adjuvant Temozolamide Beyond 6 Months in the Management of Glioblastoma Patients.
    American journal of clinical oncology, 2023, 03-01, Volume: 46, Issue:3

    Topics: Adjuvants, Immunologic; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant;

2023
Anti-seed PNAs targeting multiple oncomiRs for brain tumor therapy.
    Science advances, 2023, 02-10, Volume: 9, Issue:6

    Topics: Animals; Brain; Brain Neoplasms; Cell Line, Tumor; Glioblastoma; Mice; Nanoparticles; Peptide Nuclei

2023
Anti-seed PNAs targeting multiple oncomiRs for brain tumor therapy.
    Science advances, 2023, 02-10, Volume: 9, Issue:6

    Topics: Animals; Brain; Brain Neoplasms; Cell Line, Tumor; Glioblastoma; Mice; Nanoparticles; Peptide Nuclei

2023
Anti-seed PNAs targeting multiple oncomiRs for brain tumor therapy.
    Science advances, 2023, 02-10, Volume: 9, Issue:6

    Topics: Animals; Brain; Brain Neoplasms; Cell Line, Tumor; Glioblastoma; Mice; Nanoparticles; Peptide Nuclei

2023
Exosome-transmitted circCABIN1 promotes temozolomide resistance in glioblastoma via sustaining ErbB downstream signaling.
    Journal of nanobiotechnology, 2023, Feb-08, Volume: 21, Issue:1

    Topics: Animals; Brain Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; Exosomes; Glioblastoma; Glyco

2023
Exosome-transmitted circCABIN1 promotes temozolomide resistance in glioblastoma via sustaining ErbB downstream signaling.
    Journal of nanobiotechnology, 2023, Feb-08, Volume: 21, Issue:1

    Topics: Animals; Brain Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; Exosomes; Glioblastoma; Glyco

2023
Exosome-transmitted circCABIN1 promotes temozolomide resistance in glioblastoma via sustaining ErbB downstream signaling.
    Journal of nanobiotechnology, 2023, Feb-08, Volume: 21, Issue:1

    Topics: Animals; Brain Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; Exosomes; Glioblastoma; Glyco

2023
Prognostic Factors of Gliosarcoma in the Real World: A Retrospective Cohort Study.
    Computational and mathematical methods in medicine, 2023, Volume: 2023

    Topics: Brain Neoplasms; Glioblastoma; Gliosarcoma; Humans; Ki-67 Antigen; Neoplasm Recurrence, Local; Progn

2023
Prognostic Factors of Gliosarcoma in the Real World: A Retrospective Cohort Study.
    Computational and mathematical methods in medicine, 2023, Volume: 2023

    Topics: Brain Neoplasms; Glioblastoma; Gliosarcoma; Humans; Ki-67 Antigen; Neoplasm Recurrence, Local; Progn

2023
Prognostic Factors of Gliosarcoma in the Real World: A Retrospective Cohort Study.
    Computational and mathematical methods in medicine, 2023, Volume: 2023

    Topics: Brain Neoplasms; Glioblastoma; Gliosarcoma; Humans; Ki-67 Antigen; Neoplasm Recurrence, Local; Progn

2023
Photodynamic therapy enhances the cytotoxicity of temozolomide against glioblastoma via reprogramming anaerobic glycolysis.
    Photodiagnosis and photodynamic therapy, 2023, Volume: 42

    Topics: Anaerobiosis; Animals; Apoptosis; Brain Neoplasms; Caspase 3; Cell Line, Tumor; Glioblastoma; Glioma

2023
Photodynamic therapy enhances the cytotoxicity of temozolomide against glioblastoma via reprogramming anaerobic glycolysis.
    Photodiagnosis and photodynamic therapy, 2023, Volume: 42

    Topics: Anaerobiosis; Animals; Apoptosis; Brain Neoplasms; Caspase 3; Cell Line, Tumor; Glioblastoma; Glioma

2023
Photodynamic therapy enhances the cytotoxicity of temozolomide against glioblastoma via reprogramming anaerobic glycolysis.
    Photodiagnosis and photodynamic therapy, 2023, Volume: 42

    Topics: Anaerobiosis; Animals; Apoptosis; Brain Neoplasms; Caspase 3; Cell Line, Tumor; Glioblastoma; Glioma

2023
The PYK2 inhibitor PF-562271 enhances the effect of temozolomide on tumor growth in a C57Bl/6-Gl261 mouse glioma model.
    Journal of neuro-oncology, 2023, Volume: 161, Issue:3

    Topics: Animals; Brain Neoplasms; Cell Line, Tumor; Focal Adhesion Kinase 2; Glioblastoma; Glioma; Humans; M

2023
The PYK2 inhibitor PF-562271 enhances the effect of temozolomide on tumor growth in a C57Bl/6-Gl261 mouse glioma model.
    Journal of neuro-oncology, 2023, Volume: 161, Issue:3

    Topics: Animals; Brain Neoplasms; Cell Line, Tumor; Focal Adhesion Kinase 2; Glioblastoma; Glioma; Humans; M

2023
The PYK2 inhibitor PF-562271 enhances the effect of temozolomide on tumor growth in a C57Bl/6-Gl261 mouse glioma model.
    Journal of neuro-oncology, 2023, Volume: 161, Issue:3

    Topics: Animals; Brain Neoplasms; Cell Line, Tumor; Focal Adhesion Kinase 2; Glioblastoma; Glioma; Humans; M

2023
Antisecretory factor is safe to use as add-on treatment in newly diagnosed glioblastoma.
    BMC neurology, 2023, Feb-18, Volume: 23, Issue:1

    Topics: Adult; Antineoplastic Agents, Alkylating; Brain Neoplasms; Glioblastoma; Humans; Pilot Projects; Tem

2023
Antisecretory factor is safe to use as add-on treatment in newly diagnosed glioblastoma.
    BMC neurology, 2023, Feb-18, Volume: 23, Issue:1

    Topics: Adult; Antineoplastic Agents, Alkylating; Brain Neoplasms; Glioblastoma; Humans; Pilot Projects; Tem

2023
Antisecretory factor is safe to use as add-on treatment in newly diagnosed glioblastoma.
    BMC neurology, 2023, Feb-18, Volume: 23, Issue:1

    Topics: Adult; Antineoplastic Agents, Alkylating; Brain Neoplasms; Glioblastoma; Humans; Pilot Projects; Tem

2023
RADIOSURGICAL TREATMENT OF RECURRENT GLIOBLASTOMA AND PROGNOSTIC FACTORS AFFECTING TREATMENT OUTCOMES.
    Experimental oncology, 2022, Volume: 44, Issue:4

    Topics: Adult; Brain Neoplasms; Glioblastoma; Humans; Neoplasm Recurrence, Local; Prognosis; Radiosurgery; R

2022
RADIOSURGICAL TREATMENT OF RECURRENT GLIOBLASTOMA AND PROGNOSTIC FACTORS AFFECTING TREATMENT OUTCOMES.
    Experimental oncology, 2022, Volume: 44, Issue:4

    Topics: Adult; Brain Neoplasms; Glioblastoma; Humans; Neoplasm Recurrence, Local; Prognosis; Radiosurgery; R

2022
RADIOSURGICAL TREATMENT OF RECURRENT GLIOBLASTOMA AND PROGNOSTIC FACTORS AFFECTING TREATMENT OUTCOMES.
    Experimental oncology, 2022, Volume: 44, Issue:4

    Topics: Adult; Brain Neoplasms; Glioblastoma; Humans; Neoplasm Recurrence, Local; Prognosis; Radiosurgery; R

2022
Erythrose inhibits the progression to invasiveness and reverts drug resistance of cancer stem cells of glioblastoma.
    Medical oncology (Northwood, London, England), 2023, Feb-23, Volume: 40, Issue:3

    Topics: Brain Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; Glioblastoma; Humans; Neoplastic Stem

2023
Erythrose inhibits the progression to invasiveness and reverts drug resistance of cancer stem cells of glioblastoma.
    Medical oncology (Northwood, London, England), 2023, Feb-23, Volume: 40, Issue:3

    Topics: Brain Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; Glioblastoma; Humans; Neoplastic Stem

2023
Erythrose inhibits the progression to invasiveness and reverts drug resistance of cancer stem cells of glioblastoma.
    Medical oncology (Northwood, London, England), 2023, Feb-23, Volume: 40, Issue:3

    Topics: Brain Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; Glioblastoma; Humans; Neoplastic Stem

2023
The development of a rapid patient-derived xenograft model to predict chemotherapeutic drug sensitivity/resistance in malignant glial tumors.
    Neuro-oncology, 2023, 09-05, Volume: 25, Issue:9

    Topics: Animals; Brain Neoplasms; Carboplatin; Chick Embryo; Disease Models, Animal; Glioma; Heterografts; H

2023
The development of a rapid patient-derived xenograft model to predict chemotherapeutic drug sensitivity/resistance in malignant glial tumors.
    Neuro-oncology, 2023, 09-05, Volume: 25, Issue:9

    Topics: Animals; Brain Neoplasms; Carboplatin; Chick Embryo; Disease Models, Animal; Glioma; Heterografts; H

2023
The development of a rapid patient-derived xenograft model to predict chemotherapeutic drug sensitivity/resistance in malignant glial tumors.
    Neuro-oncology, 2023, 09-05, Volume: 25, Issue:9

    Topics: Animals; Brain Neoplasms; Carboplatin; Chick Embryo; Disease Models, Animal; Glioma; Heterografts; H

2023
Purinergic approach to effective glioma treatment with temozolomide reveals enhanced anti-cancer effects mediated by P2X7 receptor.
    Cellular signalling, 2023, Volume: 106

    Topics: Adenosine Triphosphate; Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cell Line, Tu

2023
Purinergic approach to effective glioma treatment with temozolomide reveals enhanced anti-cancer effects mediated by P2X7 receptor.
    Cellular signalling, 2023, Volume: 106

    Topics: Adenosine Triphosphate; Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cell Line, Tu

2023
Purinergic approach to effective glioma treatment with temozolomide reveals enhanced anti-cancer effects mediated by P2X7 receptor.
    Cellular signalling, 2023, Volume: 106

    Topics: Adenosine Triphosphate; Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cell Line, Tu

2023
Metronomic Temozolomide in Heavily Pretreated Patients With Recurrent Isocitrate Dehydrogenase Wild-type Glioblastoma: A Large Real-Life Mono-Institutional Study.
    Clinical oncology (Royal College of Radiologists (Great Britain)), 2023, Volume: 35, Issue:5

    Topics: Adult; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; DNA Methylation; DNA Modific

2023
Metronomic Temozolomide in Heavily Pretreated Patients With Recurrent Isocitrate Dehydrogenase Wild-type Glioblastoma: A Large Real-Life Mono-Institutional Study.
    Clinical oncology (Royal College of Radiologists (Great Britain)), 2023, Volume: 35, Issue:5

    Topics: Adult; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; DNA Methylation; DNA Modific

2023
Metronomic Temozolomide in Heavily Pretreated Patients With Recurrent Isocitrate Dehydrogenase Wild-type Glioblastoma: A Large Real-Life Mono-Institutional Study.
    Clinical oncology (Royal College of Radiologists (Great Britain)), 2023, Volume: 35, Issue:5

    Topics: Adult; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; DNA Methylation; DNA Modific

2023
Letter to the editor regarding "The efficacy and safety of radiotherapy with adjuvant temozolomide for glioblastoma: A meta-analysis of randomized controlled studies".
    Clinical neurology and neurosurgery, 2023, Volume: 227

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant; Dacarbazine; Glioblastom

2023
Letter to the editor regarding "The efficacy and safety of radiotherapy with adjuvant temozolomide for glioblastoma: A meta-analysis of randomized controlled studies".
    Clinical neurology and neurosurgery, 2023, Volume: 227

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant; Dacarbazine; Glioblastom

2023
Letter to the editor regarding "The efficacy and safety of radiotherapy with adjuvant temozolomide for glioblastoma: A meta-analysis of randomized controlled studies".
    Clinical neurology and neurosurgery, 2023, Volume: 227

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant; Dacarbazine; Glioblastom

2023
E3 ligase MAEA-mediated ubiquitination and degradation of PHD3 promotes glioblastoma progression.
    Oncogene, 2023, Volume: 42, Issue:16

    Topics: Brain Neoplasms; Cell Adhesion Molecules; Cell Line, Tumor; Cytoskeletal Proteins; Drug Resistance,

2023
E3 ligase MAEA-mediated ubiquitination and degradation of PHD3 promotes glioblastoma progression.
    Oncogene, 2023, Volume: 42, Issue:16

    Topics: Brain Neoplasms; Cell Adhesion Molecules; Cell Line, Tumor; Cytoskeletal Proteins; Drug Resistance,

2023
E3 ligase MAEA-mediated ubiquitination and degradation of PHD3 promotes glioblastoma progression.
    Oncogene, 2023, Volume: 42, Issue:16

    Topics: Brain Neoplasms; Cell Adhesion Molecules; Cell Line, Tumor; Cytoskeletal Proteins; Drug Resistance,

2023
Systematic in vitro analysis of therapy resistance in glioblastoma cell lines by integration of clonogenic survival data with multi-level molecular data.
    Radiation oncology (London, England), 2023, Mar-11, Volume: 18, Issue:1

    Topics: Brain Neoplasms; Cell Line, Tumor; Glioblastoma; Humans; Prognosis; Signal Transduction; Temozolomid

2023
Systematic in vitro analysis of therapy resistance in glioblastoma cell lines by integration of clonogenic survival data with multi-level molecular data.
    Radiation oncology (London, England), 2023, Mar-11, Volume: 18, Issue:1

    Topics: Brain Neoplasms; Cell Line, Tumor; Glioblastoma; Humans; Prognosis; Signal Transduction; Temozolomid

2023
Systematic in vitro analysis of therapy resistance in glioblastoma cell lines by integration of clonogenic survival data with multi-level molecular data.
    Radiation oncology (London, England), 2023, Mar-11, Volume: 18, Issue:1

    Topics: Brain Neoplasms; Cell Line, Tumor; Glioblastoma; Humans; Prognosis; Signal Transduction; Temozolomid

2023
Almonertinib Combined with Anlotinib and Temozolomide in a Patient with Recurrent Glioblastoma with EGFR L858R Mutation.
    The oncologist, 2023, 05-08, Volume: 28, Issue:5

    Topics: Brain Neoplasms; ErbB Receptors; Glioblastoma; Humans; Mutation; Temozolomide

2023
Almonertinib Combined with Anlotinib and Temozolomide in a Patient with Recurrent Glioblastoma with EGFR L858R Mutation.
    The oncologist, 2023, 05-08, Volume: 28, Issue:5

    Topics: Brain Neoplasms; ErbB Receptors; Glioblastoma; Humans; Mutation; Temozolomide

2023
Almonertinib Combined with Anlotinib and Temozolomide in a Patient with Recurrent Glioblastoma with EGFR L858R Mutation.
    The oncologist, 2023, 05-08, Volume: 28, Issue:5

    Topics: Brain Neoplasms; ErbB Receptors; Glioblastoma; Humans; Mutation; Temozolomide

2023
Pharmacogenomic profiling reveals molecular features of chemotherapy resistance in IDH wild-type primary glioblastoma.
    Genome medicine, 2023, 03-13, Volume: 15, Issue:1

    Topics: Brain Neoplasms; Drug Resistance, Neoplasm; Early Growth Response Transcription Factors; Glioblastom

2023
Pharmacogenomic profiling reveals molecular features of chemotherapy resistance in IDH wild-type primary glioblastoma.
    Genome medicine, 2023, 03-13, Volume: 15, Issue:1

    Topics: Brain Neoplasms; Drug Resistance, Neoplasm; Early Growth Response Transcription Factors; Glioblastom

2023
Pharmacogenomic profiling reveals molecular features of chemotherapy resistance in IDH wild-type primary glioblastoma.
    Genome medicine, 2023, 03-13, Volume: 15, Issue:1

    Topics: Brain Neoplasms; Drug Resistance, Neoplasm; Early Growth Response Transcription Factors; Glioblastom

2023
Exploring temozolomide encapsulated PEGylated liposomes and lyotropic liquid crystals for effective treatment of glioblastoma: in-vitro, cell line, and pharmacokinetic studies.
    European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 2023, Volume: 186

    Topics: Brain Neoplasms; Cell Line, Tumor; Glioblastoma; Humans; Liposomes; Liquid Crystals; Polyethylene Gl

2023
Exploring temozolomide encapsulated PEGylated liposomes and lyotropic liquid crystals for effective treatment of glioblastoma: in-vitro, cell line, and pharmacokinetic studies.
    European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 2023, Volume: 186

    Topics: Brain Neoplasms; Cell Line, Tumor; Glioblastoma; Humans; Liposomes; Liquid Crystals; Polyethylene Gl

2023
Exploring temozolomide encapsulated PEGylated liposomes and lyotropic liquid crystals for effective treatment of glioblastoma: in-vitro, cell line, and pharmacokinetic studies.
    European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 2023, Volume: 186

    Topics: Brain Neoplasms; Cell Line, Tumor; Glioblastoma; Humans; Liposomes; Liquid Crystals; Polyethylene Gl

2023
Gut microbiota mediated the individualized efficacy of Temozolomide via immunomodulation in glioma.
    Journal of translational medicine, 2023, 03-16, Volume: 21, Issue:1

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Drug Resistance, Neop

2023
Gut microbiota mediated the individualized efficacy of Temozolomide via immunomodulation in glioma.
    Journal of translational medicine, 2023, 03-16, Volume: 21, Issue:1

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Drug Resistance, Neop

2023
Gut microbiota mediated the individualized efficacy of Temozolomide via immunomodulation in glioma.
    Journal of translational medicine, 2023, 03-16, Volume: 21, Issue:1

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Drug Resistance, Neop

2023
Targeting unfolded protein response using albumin-encapsulated nanoparticles attenuates temozolomide resistance in glioblastoma.
    British journal of cancer, 2023, Volume: 128, Issue:10

    Topics: Albumins; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; Glioblastoma; Hum

2023
Targeting unfolded protein response using albumin-encapsulated nanoparticles attenuates temozolomide resistance in glioblastoma.
    British journal of cancer, 2023, Volume: 128, Issue:10

    Topics: Albumins; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; Glioblastoma; Hum

2023
Targeting unfolded protein response using albumin-encapsulated nanoparticles attenuates temozolomide resistance in glioblastoma.
    British journal of cancer, 2023, Volume: 128, Issue:10

    Topics: Albumins; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; Glioblastoma; Hum

2023
Loco-regional treatment with temozolomide-loaded thermogels prevents glioblastoma recurrences in orthotopic human xenograft models.
    Scientific reports, 2023, 03-21, Volume: 13, Issue:1

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Drug Resistance, Neop

2023
Loco-regional treatment with temozolomide-loaded thermogels prevents glioblastoma recurrences in orthotopic human xenograft models.
    Scientific reports, 2023, 03-21, Volume: 13, Issue:1

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Drug Resistance, Neop

2023
Loco-regional treatment with temozolomide-loaded thermogels prevents glioblastoma recurrences in orthotopic human xenograft models.
    Scientific reports, 2023, 03-21, Volume: 13, Issue:1

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Drug Resistance, Neop

2023
Downregulation of BASP1 Promotes Temozolomide Resistance in Gliomas via Epigenetic Activation of the FBXO32/NF-κB/MGMT Axis.
    Molecular cancer research : MCR, 2023, 07-05, Volume: 21, Issue:7

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; DNA Modification Methylases; DNA Repair Enzymes;

2023
Downregulation of BASP1 Promotes Temozolomide Resistance in Gliomas via Epigenetic Activation of the FBXO32/NF-κB/MGMT Axis.
    Molecular cancer research : MCR, 2023, 07-05, Volume: 21, Issue:7

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; DNA Modification Methylases; DNA Repair Enzymes;

2023
Downregulation of BASP1 Promotes Temozolomide Resistance in Gliomas via Epigenetic Activation of the FBXO32/NF-κB/MGMT Axis.
    Molecular cancer research : MCR, 2023, 07-05, Volume: 21, Issue:7

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; DNA Modification Methylases; DNA Repair Enzymes;

2023
Efficient delivery of Temozolomide using ultrasmall large-pore silica nanoparticles for glioblastoma.
    Journal of controlled release : official journal of the Controlled Release Society, 2023, Volume: 357

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain; Brain Neoplasms; Cell Line, Tumor; Glioblastoma;

2023
Efficient delivery of Temozolomide using ultrasmall large-pore silica nanoparticles for glioblastoma.
    Journal of controlled release : official journal of the Controlled Release Society, 2023, Volume: 357

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain; Brain Neoplasms; Cell Line, Tumor; Glioblastoma;

2023
Efficient delivery of Temozolomide using ultrasmall large-pore silica nanoparticles for glioblastoma.
    Journal of controlled release : official journal of the Controlled Release Society, 2023, Volume: 357

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain; Brain Neoplasms; Cell Line, Tumor; Glioblastoma;

2023
Sitagliptin inhibits the survival, stemness and autophagy of glioma cells, and enhances temozolomide cytotoxicity.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2023, Volume: 162

    Topics: Animals; Antineoplastic Agents, Alkylating; Apoptosis; Autophagy; Brain Neoplasms; Cell Line, Tumor;

2023
Sitagliptin inhibits the survival, stemness and autophagy of glioma cells, and enhances temozolomide cytotoxicity.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2023, Volume: 162

    Topics: Animals; Antineoplastic Agents, Alkylating; Apoptosis; Autophagy; Brain Neoplasms; Cell Line, Tumor;

2023
Sitagliptin inhibits the survival, stemness and autophagy of glioma cells, and enhances temozolomide cytotoxicity.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2023, Volume: 162

    Topics: Animals; Antineoplastic Agents, Alkylating; Apoptosis; Autophagy; Brain Neoplasms; Cell Line, Tumor;

2023
Mechanical nanosurgery of chemoresistant glioblastoma using magnetically controlled carbon nanotubes.
    Science advances, 2023, 03-29, Volume: 9, Issue:13

    Topics: Animals; Brain Neoplasms; Cell Death; Cell Line, Tumor; Glioblastoma; Mice; Nanotubes, Carbon; Temoz

2023
Mechanical nanosurgery of chemoresistant glioblastoma using magnetically controlled carbon nanotubes.
    Science advances, 2023, 03-29, Volume: 9, Issue:13

    Topics: Animals; Brain Neoplasms; Cell Death; Cell Line, Tumor; Glioblastoma; Mice; Nanotubes, Carbon; Temoz

2023
Mechanical nanosurgery of chemoresistant glioblastoma using magnetically controlled carbon nanotubes.
    Science advances, 2023, 03-29, Volume: 9, Issue:13

    Topics: Animals; Brain Neoplasms; Cell Death; Cell Line, Tumor; Glioblastoma; Mice; Nanotubes, Carbon; Temoz

2023
Nanocomposite formulation for a sustained release of free drug and drug-loaded responsive nanoparticles: an approach for a local therapy of glioblastoma multiforme.
    Scientific reports, 2023, 03-29, Volume: 13, Issue:1

    Topics: Adult; Brain Neoplasms; Cell Line, Tumor; Delayed-Action Preparations; Glioblastoma; Humans; Hydroge

2023
Nanocomposite formulation for a sustained release of free drug and drug-loaded responsive nanoparticles: an approach for a local therapy of glioblastoma multiforme.
    Scientific reports, 2023, 03-29, Volume: 13, Issue:1

    Topics: Adult; Brain Neoplasms; Cell Line, Tumor; Delayed-Action Preparations; Glioblastoma; Humans; Hydroge

2023
Nanocomposite formulation for a sustained release of free drug and drug-loaded responsive nanoparticles: an approach for a local therapy of glioblastoma multiforme.
    Scientific reports, 2023, 03-29, Volume: 13, Issue:1

    Topics: Adult; Brain Neoplasms; Cell Line, Tumor; Delayed-Action Preparations; Glioblastoma; Humans; Hydroge

2023
SRSF4 Confers Temozolomide Resistance of Glioma via Accelerating Double Strand Break Repair.
    Journal of molecular neuroscience : MN, 2023, Volume: 73, Issue:4-5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; DNA Repair; Drug Resistance, N

2023
SRSF4 Confers Temozolomide Resistance of Glioma via Accelerating Double Strand Break Repair.
    Journal of molecular neuroscience : MN, 2023, Volume: 73, Issue:4-5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; DNA Repair; Drug Resistance, N

2023
SRSF4 Confers Temozolomide Resistance of Glioma via Accelerating Double Strand Break Repair.
    Journal of molecular neuroscience : MN, 2023, Volume: 73, Issue:4-5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; DNA Repair; Drug Resistance, N

2023
Exosomes released from U87 glioma cells treated with curcumin and/or temozolomide produce apoptosis in naive U87 cells.
    Pathology, research and practice, 2023, Volume: 245

    Topics: Animals; Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Brain-Derived Neurotrophic F

2023
Exosomes released from U87 glioma cells treated with curcumin and/or temozolomide produce apoptosis in naive U87 cells.
    Pathology, research and practice, 2023, Volume: 245

    Topics: Animals; Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Brain-Derived Neurotrophic F

2023
Exosomes released from U87 glioma cells treated with curcumin and/or temozolomide produce apoptosis in naive U87 cells.
    Pathology, research and practice, 2023, Volume: 245

    Topics: Animals; Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Brain-Derived Neurotrophic F

2023
Influence of MMR, MGMT Promotor Methylation and Protein Expression on Overall and Progression-Free Survival in Primary Glioblastoma Patients Treated with Temozolomide.
    International journal of molecular sciences, 2023, Mar-24, Volume: 24, Issue:7

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; DNA Methylation; DNA M

2023
Influence of MMR, MGMT Promotor Methylation and Protein Expression on Overall and Progression-Free Survival in Primary Glioblastoma Patients Treated with Temozolomide.
    International journal of molecular sciences, 2023, Mar-24, Volume: 24, Issue:7

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; DNA Methylation; DNA M

2023
Influence of MMR, MGMT Promotor Methylation and Protein Expression on Overall and Progression-Free Survival in Primary Glioblastoma Patients Treated with Temozolomide.
    International journal of molecular sciences, 2023, Mar-24, Volume: 24, Issue:7

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; DNA Methylation; DNA M

2023
Metastatic Melanoma: A Preclinical Model Standardization and Development of a Chitosan-Coated Nanoemulsion Containing Temozolomide to Treat Brain Metastasis.
    Cellular and molecular neurobiology, 2023, Volume: 43, Issue:6

    Topics: Animals; Brain Neoplasms; Cell Line, Tumor; Chitosan; Dacarbazine; Humans; Melanoma; Mice; Temozolom

2023
Metastatic Melanoma: A Preclinical Model Standardization and Development of a Chitosan-Coated Nanoemulsion Containing Temozolomide to Treat Brain Metastasis.
    Cellular and molecular neurobiology, 2023, Volume: 43, Issue:6

    Topics: Animals; Brain Neoplasms; Cell Line, Tumor; Chitosan; Dacarbazine; Humans; Melanoma; Mice; Temozolom

2023
Metastatic Melanoma: A Preclinical Model Standardization and Development of a Chitosan-Coated Nanoemulsion Containing Temozolomide to Treat Brain Metastasis.
    Cellular and molecular neurobiology, 2023, Volume: 43, Issue:6

    Topics: Animals; Brain Neoplasms; Cell Line, Tumor; Chitosan; Dacarbazine; Humans; Melanoma; Mice; Temozolom

2023
RNA cytosine methyltransferase NSUN5 promotes protein synthesis and tumorigenic phenotypes in glioblastoma.
    Molecular oncology, 2023, Volume: 17, Issue:9

    Topics: Animals; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Gene Expression Regulation, Neoplast

2023
RNA cytosine methyltransferase NSUN5 promotes protein synthesis and tumorigenic phenotypes in glioblastoma.
    Molecular oncology, 2023, Volume: 17, Issue:9

    Topics: Animals; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Gene Expression Regulation, Neoplast

2023
RNA cytosine methyltransferase NSUN5 promotes protein synthesis and tumorigenic phenotypes in glioblastoma.
    Molecular oncology, 2023, Volume: 17, Issue:9

    Topics: Animals; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Gene Expression Regulation, Neoplast

2023
Very long-term survival of an older glioblastoma patient after treatment with cilengitide: a case report.
    CNS oncology, 2023, 06-01, Volume: 12, Issue:2

    Topics: Brain Neoplasms; Child; Dacarbazine; DNA Methylation; DNA Modification Methylases; DNA Repair Enzyme

2023
Very long-term survival of an older glioblastoma patient after treatment with cilengitide: a case report.
    CNS oncology, 2023, 06-01, Volume: 12, Issue:2

    Topics: Brain Neoplasms; Child; Dacarbazine; DNA Methylation; DNA Modification Methylases; DNA Repair Enzyme

2023
Very long-term survival of an older glioblastoma patient after treatment with cilengitide: a case report.
    CNS oncology, 2023, 06-01, Volume: 12, Issue:2

    Topics: Brain Neoplasms; Child; Dacarbazine; DNA Methylation; DNA Modification Methylases; DNA Repair Enzyme

2023
Juglone in Combination with Temozolomide Shows a Promising Epigenetic Therapeutic Effect on the Glioblastoma Cell Line.
    International journal of molecular sciences, 2023, Apr-10, Volume: 24, Issue:8

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; Epi

2023
Juglone in Combination with Temozolomide Shows a Promising Epigenetic Therapeutic Effect on the Glioblastoma Cell Line.
    International journal of molecular sciences, 2023, Apr-10, Volume: 24, Issue:8

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; Epi

2023
Juglone in Combination with Temozolomide Shows a Promising Epigenetic Therapeutic Effect on the Glioblastoma Cell Line.
    International journal of molecular sciences, 2023, Apr-10, Volume: 24, Issue:8

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; Epi

2023
Tumor Treating Fields (TTFields) increase the effectiveness of temozolomide and lomustine in glioblastoma cell lines.
    Journal of neuro-oncology, 2023, Volume: 163, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line; Cell Line, Tumor; DNA Modification Me

2023
Tumor Treating Fields (TTFields) increase the effectiveness of temozolomide and lomustine in glioblastoma cell lines.
    Journal of neuro-oncology, 2023, Volume: 163, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line; Cell Line, Tumor; DNA Modification Me

2023
Tumor Treating Fields (TTFields) increase the effectiveness of temozolomide and lomustine in glioblastoma cell lines.
    Journal of neuro-oncology, 2023, Volume: 163, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line; Cell Line, Tumor; DNA Modification Me

2023
Development and Validation of a Targeted Treatment for Brain Tumors Using a Multi-Drug Loaded, Relapse-Resistant Polymeric Theranostic.
    Biomacromolecules, 2023, 06-12, Volume: 24, Issue:6

    Topics: Brain Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; Glioblastoma; Humans; Neoplasm Recurre

2023
Development and Validation of a Targeted Treatment for Brain Tumors Using a Multi-Drug Loaded, Relapse-Resistant Polymeric Theranostic.
    Biomacromolecules, 2023, 06-12, Volume: 24, Issue:6

    Topics: Brain Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; Glioblastoma; Humans; Neoplasm Recurre

2023
Development and Validation of a Targeted Treatment for Brain Tumors Using a Multi-Drug Loaded, Relapse-Resistant Polymeric Theranostic.
    Biomacromolecules, 2023, 06-12, Volume: 24, Issue:6

    Topics: Brain Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; Glioblastoma; Humans; Neoplasm Recurre

2023
Repurposing FDA-Approved Drugs for Temozolomide-Resistant IDH1 Mutant Glioma Using High-Throughput Miniaturized Screening on Droplet Microarray Chip.
    Advanced healthcare materials, 2023, Volume: 12, Issue:24

    Topics: Brain Neoplasms; Drug Repositioning; Glioma; Humans; Isocitrate Dehydrogenase; Temozolomide

2023
Repurposing FDA-Approved Drugs for Temozolomide-Resistant IDH1 Mutant Glioma Using High-Throughput Miniaturized Screening on Droplet Microarray Chip.
    Advanced healthcare materials, 2023, Volume: 12, Issue:24

    Topics: Brain Neoplasms; Drug Repositioning; Glioma; Humans; Isocitrate Dehydrogenase; Temozolomide

2023
Repurposing FDA-Approved Drugs for Temozolomide-Resistant IDH1 Mutant Glioma Using High-Throughput Miniaturized Screening on Droplet Microarray Chip.
    Advanced healthcare materials, 2023, Volume: 12, Issue:24

    Topics: Brain Neoplasms; Drug Repositioning; Glioma; Humans; Isocitrate Dehydrogenase; Temozolomide

2023
Incidence of clinically relevant psychiatric symptoms during glioblastoma treatment: an exploratory study.
    Journal of neuro-oncology, 2023, Volume: 163, Issue:1

    Topics: Brain Neoplasms; Glioblastoma; Humans; Incidence; Male; Mental Disorders; Quality of Life; Retrospec

2023
Incidence of clinically relevant psychiatric symptoms during glioblastoma treatment: an exploratory study.
    Journal of neuro-oncology, 2023, Volume: 163, Issue:1

    Topics: Brain Neoplasms; Glioblastoma; Humans; Incidence; Male; Mental Disorders; Quality of Life; Retrospec

2023
Incidence of clinically relevant psychiatric symptoms during glioblastoma treatment: an exploratory study.
    Journal of neuro-oncology, 2023, Volume: 163, Issue:1

    Topics: Brain Neoplasms; Glioblastoma; Humans; Incidence; Male; Mental Disorders; Quality of Life; Retrospec

2023
Acetogenins-Rich Fractions of
    Molecules (Basel, Switzerland), 2023, Apr-29, Volume: 28, Issue:9

    Topics: Acetogenins; Annona; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; Gliobl

2023
Acetogenins-Rich Fractions of
    Molecules (Basel, Switzerland), 2023, Apr-29, Volume: 28, Issue:9

    Topics: Acetogenins; Annona; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; Gliobl

2023
Acetogenins-Rich Fractions of
    Molecules (Basel, Switzerland), 2023, Apr-29, Volume: 28, Issue:9

    Topics: Acetogenins; Annona; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; Gliobl

2023
ADAM17 Confers Temozolomide Resistance in Human Glioblastoma Cells and miR-145 Regulates Its Expression.
    International journal of molecular sciences, 2023, Apr-22, Volume: 24, Issue:9

    Topics: ADAM17 Protein; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Down-Regulatio

2023
ADAM17 Confers Temozolomide Resistance in Human Glioblastoma Cells and miR-145 Regulates Its Expression.
    International journal of molecular sciences, 2023, Apr-22, Volume: 24, Issue:9

    Topics: ADAM17 Protein; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Down-Regulatio

2023
ADAM17 Confers Temozolomide Resistance in Human Glioblastoma Cells and miR-145 Regulates Its Expression.
    International journal of molecular sciences, 2023, Apr-22, Volume: 24, Issue:9

    Topics: ADAM17 Protein; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Down-Regulatio

2023
NADPH Oxidase Subunit CYBB Confers Chemotherapy and Ferroptosis Resistance in Mesenchymal Glioblastoma via Nrf2/SOD2 Modulation.
    International journal of molecular sciences, 2023, Apr-22, Volume: 24, Issue:9

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Drug Resistance, Neop

2023
NADPH Oxidase Subunit CYBB Confers Chemotherapy and Ferroptosis Resistance in Mesenchymal Glioblastoma via Nrf2/SOD2 Modulation.
    International journal of molecular sciences, 2023, Apr-22, Volume: 24, Issue:9

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Drug Resistance, Neop

2023
NADPH Oxidase Subunit CYBB Confers Chemotherapy and Ferroptosis Resistance in Mesenchymal Glioblastoma via Nrf2/SOD2 Modulation.
    International journal of molecular sciences, 2023, Apr-22, Volume: 24, Issue:9

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Drug Resistance, Neop

2023
A Promising Way to Overcome Temozolomide Resistance through Inhibition of Protein Neddylation in Glioblastoma Cell Lines.
    International journal of molecular sciences, 2023, Apr-27, Volume: 24, Issue:9

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; DNA Modification Methylases; D

2023
A Promising Way to Overcome Temozolomide Resistance through Inhibition of Protein Neddylation in Glioblastoma Cell Lines.
    International journal of molecular sciences, 2023, Apr-27, Volume: 24, Issue:9

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; DNA Modification Methylases; D

2023
A Promising Way to Overcome Temozolomide Resistance through Inhibition of Protein Neddylation in Glioblastoma Cell Lines.
    International journal of molecular sciences, 2023, Apr-27, Volume: 24, Issue:9

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; DNA Modification Methylases; D

2023
UBE2T Promotes Temozolomide Resistance of Glioblastoma Through Regulating the Wnt/β-Catenin Signaling Pathway.
    Drug design, development and therapy, 2023, Volume: 17

    Topics: Animals; beta Catenin; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Drug Resistance, Neopl

2023
UBE2T Promotes Temozolomide Resistance of Glioblastoma Through Regulating the Wnt/β-Catenin Signaling Pathway.
    Drug design, development and therapy, 2023, Volume: 17

    Topics: Animals; beta Catenin; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Drug Resistance, Neopl

2023
UBE2T Promotes Temozolomide Resistance of Glioblastoma Through Regulating the Wnt/β-Catenin Signaling Pathway.
    Drug design, development and therapy, 2023, Volume: 17

    Topics: Animals; beta Catenin; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Drug Resistance, Neopl

2023
Temozolomide-fatty acid conjugates for glioblastoma multiforme: In vitro and in vivo evaluation.
    Journal of controlled release : official journal of the Controlled Release Society, 2023, Volume: 359

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Drug Resistance, Neop

2023
Temozolomide-fatty acid conjugates for glioblastoma multiforme: In vitro and in vivo evaluation.
    Journal of controlled release : official journal of the Controlled Release Society, 2023, Volume: 359

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Drug Resistance, Neop

2023
Temozolomide-fatty acid conjugates for glioblastoma multiforme: In vitro and in vivo evaluation.
    Journal of controlled release : official journal of the Controlled Release Society, 2023, Volume: 359

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Drug Resistance, Neop

2023
[Medical Treatments for Malignant Brain Tumor].
    Brain and nerve = Shinkei kenkyu no shinpo, 2023, Volume: 75, Issue:5

    Topics: Antineoplastic Agents; Brain Neoplasms; Glioma; Humans; Nitrosourea Compounds; Temozolomide

2023
[Medical Treatments for Malignant Brain Tumor].
    Brain and nerve = Shinkei kenkyu no shinpo, 2023, Volume: 75, Issue:5

    Topics: Antineoplastic Agents; Brain Neoplasms; Glioma; Humans; Nitrosourea Compounds; Temozolomide

2023
[Medical Treatments for Malignant Brain Tumor].
    Brain and nerve = Shinkei kenkyu no shinpo, 2023, Volume: 75, Issue:5

    Topics: Antineoplastic Agents; Brain Neoplasms; Glioma; Humans; Nitrosourea Compounds; Temozolomide

2023
Ribonucleotide reductase regulatory subunit M2 drives glioblastoma TMZ resistance through modulation of dNTP production.
    Science advances, 2023, 05-19, Volume: 9, Issue:20

    Topics: Brain Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; Glioblastoma; Humans; Ribonucleotide R

2023
Ribonucleotide reductase regulatory subunit M2 drives glioblastoma TMZ resistance through modulation of dNTP production.
    Science advances, 2023, 05-19, Volume: 9, Issue:20

    Topics: Brain Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; Glioblastoma; Humans; Ribonucleotide R

2023
Ribonucleotide reductase regulatory subunit M2 drives glioblastoma TMZ resistance through modulation of dNTP production.
    Science advances, 2023, 05-19, Volume: 9, Issue:20

    Topics: Brain Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; Glioblastoma; Humans; Ribonucleotide R

2023
GBP3-STING interaction in glioblastoma coordinates autophagy, anti-oxidative, and DNA repair programs in response to temozolomide.
    Oncotarget, 2023, 05-19, Volume: 14

    Topics: Antineoplastic Agents, Alkylating; Autophagy; Brain Neoplasms; Dacarbazine; DNA Modification Methyla

2023
GBP3-STING interaction in glioblastoma coordinates autophagy, anti-oxidative, and DNA repair programs in response to temozolomide.
    Oncotarget, 2023, 05-19, Volume: 14

    Topics: Antineoplastic Agents, Alkylating; Autophagy; Brain Neoplasms; Dacarbazine; DNA Modification Methyla

2023
GBP3-STING interaction in glioblastoma coordinates autophagy, anti-oxidative, and DNA repair programs in response to temozolomide.
    Oncotarget, 2023, 05-19, Volume: 14

    Topics: Antineoplastic Agents, Alkylating; Autophagy; Brain Neoplasms; Dacarbazine; DNA Modification Methyla

2023
AHR, a novel inhibitory immune checkpoint receptor, is a potential therapeutic target for chemoresistant glioblastoma.
    Journal of cancer research and clinical oncology, 2023, Volume: 149, Issue:12

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; DNA Methylation; DNA Modification Methylases; DN

2023
AHR, a novel inhibitory immune checkpoint receptor, is a potential therapeutic target for chemoresistant glioblastoma.
    Journal of cancer research and clinical oncology, 2023, Volume: 149, Issue:12

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; DNA Methylation; DNA Modification Methylases; DN

2023
AHR, a novel inhibitory immune checkpoint receptor, is a potential therapeutic target for chemoresistant glioblastoma.
    Journal of cancer research and clinical oncology, 2023, Volume: 149, Issue:12

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; DNA Methylation; DNA Modification Methylases; DN

2023
Sequential Treatment with Temozolomide Plus Naturally Derived AT101 as an Alternative Therapeutic Strategy: Insights into Chemoresistance Mechanisms of Surviving Glioblastoma Cells.
    International journal of molecular sciences, 2023, May-22, Volume: 24, Issue:10

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; Gli

2023
Sequential Treatment with Temozolomide Plus Naturally Derived AT101 as an Alternative Therapeutic Strategy: Insights into Chemoresistance Mechanisms of Surviving Glioblastoma Cells.
    International journal of molecular sciences, 2023, May-22, Volume: 24, Issue:10

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; Gli

2023
Sequential Treatment with Temozolomide Plus Naturally Derived AT101 as an Alternative Therapeutic Strategy: Insights into Chemoresistance Mechanisms of Surviving Glioblastoma Cells.
    International journal of molecular sciences, 2023, May-22, Volume: 24, Issue:10

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; Gli

2023
LncRNA CASC2 Inhibits Progression of Glioblastoma by Regulating the Expression of AKT in T98G Cell Line, Treated by TMZ and Thiosemicarbazone Complex.
    Asian Pacific journal of cancer prevention : APJCP, 2023, May-01, Volume: 24, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; Gli

2023
LncRNA CASC2 Inhibits Progression of Glioblastoma by Regulating the Expression of AKT in T98G Cell Line, Treated by TMZ and Thiosemicarbazone Complex.
    Asian Pacific journal of cancer prevention : APJCP, 2023, May-01, Volume: 24, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; Gli

2023
LncRNA CASC2 Inhibits Progression of Glioblastoma by Regulating the Expression of AKT in T98G Cell Line, Treated by TMZ and Thiosemicarbazone Complex.
    Asian Pacific journal of cancer prevention : APJCP, 2023, May-01, Volume: 24, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; Gli

2023
Combination of B7H6-siRNA and temozolomide synergistically reduces stemness and migration properties of glioblastoma cancer cells.
    Experimental cell research, 2023, Aug-01, Volume: 429, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation;

2023
Combination of B7H6-siRNA and temozolomide synergistically reduces stemness and migration properties of glioblastoma cancer cells.
    Experimental cell research, 2023, Aug-01, Volume: 429, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation;

2023
Combination of B7H6-siRNA and temozolomide synergistically reduces stemness and migration properties of glioblastoma cancer cells.
    Experimental cell research, 2023, Aug-01, Volume: 429, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation;

2023
Identification of Patients With Glioblastoma Who May Benefit from Hypofractionated Radiotherapy.
    Anticancer research, 2023, Volume: 43, Issue:6

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; DNA Methylation; DNA Modification M

2023
Identification of Patients With Glioblastoma Who May Benefit from Hypofractionated Radiotherapy.
    Anticancer research, 2023, Volume: 43, Issue:6

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; DNA Methylation; DNA Modification M

2023
Identification of Patients With Glioblastoma Who May Benefit from Hypofractionated Radiotherapy.
    Anticancer research, 2023, Volume: 43, Issue:6

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; DNA Methylation; DNA Modification M

2023
Grade scoring system reveals distinct molecular subtypes and identifies KIF20A as a novel biomarker for predicting temozolomide treatment efficiency in gliomas.
    Journal of cancer research and clinical oncology, 2023, Volume: 149, Issue:12

    Topics: Biomarkers; Brain Neoplasms; Glioblastoma; Glioma; Humans; Kinesins; Multigene Family; Prognosis; Te

2023
Grade scoring system reveals distinct molecular subtypes and identifies KIF20A as a novel biomarker for predicting temozolomide treatment efficiency in gliomas.
    Journal of cancer research and clinical oncology, 2023, Volume: 149, Issue:12

    Topics: Biomarkers; Brain Neoplasms; Glioblastoma; Glioma; Humans; Kinesins; Multigene Family; Prognosis; Te

2023
Grade scoring system reveals distinct molecular subtypes and identifies KIF20A as a novel biomarker for predicting temozolomide treatment efficiency in gliomas.
    Journal of cancer research and clinical oncology, 2023, Volume: 149, Issue:12

    Topics: Biomarkers; Brain Neoplasms; Glioblastoma; Glioma; Humans; Kinesins; Multigene Family; Prognosis; Te

2023
The DRD2 Antagonist Haloperidol Mediates Autophagy-Induced Ferroptosis to Increase Temozolomide Sensitivity by Promoting Endoplasmic Reticulum Stress in Glioblastoma.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2023, 08-15, Volume: 29, Issue:16

    Topics: Autophagy; Brain Neoplasms; Cell Line, Tumor; Dopamine D2 Receptor Antagonists; Drug Resistance, Neo

2023
The DRD2 Antagonist Haloperidol Mediates Autophagy-Induced Ferroptosis to Increase Temozolomide Sensitivity by Promoting Endoplasmic Reticulum Stress in Glioblastoma.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2023, 08-15, Volume: 29, Issue:16

    Topics: Autophagy; Brain Neoplasms; Cell Line, Tumor; Dopamine D2 Receptor Antagonists; Drug Resistance, Neo

2023
The DRD2 Antagonist Haloperidol Mediates Autophagy-Induced Ferroptosis to Increase Temozolomide Sensitivity by Promoting Endoplasmic Reticulum Stress in Glioblastoma.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2023, 08-15, Volume: 29, Issue:16

    Topics: Autophagy; Brain Neoplasms; Cell Line, Tumor; Dopamine D2 Receptor Antagonists; Drug Resistance, Neo

2023
Discovery of new imidazotetrazinones with potential to overcome tumor resistance.
    European journal of medicinal chemistry, 2023, Sep-05, Volume: 257

    Topics: Antineoplastic Agents; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Dacarba

2023
Discovery of new imidazotetrazinones with potential to overcome tumor resistance.
    European journal of medicinal chemistry, 2023, Sep-05, Volume: 257

    Topics: Antineoplastic Agents; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Dacarba

2023
Discovery of new imidazotetrazinones with potential to overcome tumor resistance.
    European journal of medicinal chemistry, 2023, Sep-05, Volume: 257

    Topics: Antineoplastic Agents; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Dacarba

2023
Reduced YAP1 and FOLR1 in gliomas predict better response to chemotherapeutics.
    Cellular signalling, 2023, Volume: 109

    Topics: Brain Neoplasms; Folate Receptor 1; Glioma; Humans; Interleukin-6; Interleukin-8; Mutation; Temozolo

2023
Reduced YAP1 and FOLR1 in gliomas predict better response to chemotherapeutics.
    Cellular signalling, 2023, Volume: 109

    Topics: Brain Neoplasms; Folate Receptor 1; Glioma; Humans; Interleukin-6; Interleukin-8; Mutation; Temozolo

2023
Reduced YAP1 and FOLR1 in gliomas predict better response to chemotherapeutics.
    Cellular signalling, 2023, Volume: 109

    Topics: Brain Neoplasms; Folate Receptor 1; Glioma; Humans; Interleukin-6; Interleukin-8; Mutation; Temozolo

2023
The interplay of solvent-drug-protein interactions during albumin nanoparticles formulations for temozolomide delivery to brain cancer cells.
    The Journal of pharmacy and pharmacology, 2023, Jul-05, Volume: 75, Issue:7

    Topics: Acetone; Brain Neoplasms; Cell Line, Tumor; Ethanol; Glioblastoma; Humans; Nanoparticles; Serum Albu

2023
The interplay of solvent-drug-protein interactions during albumin nanoparticles formulations for temozolomide delivery to brain cancer cells.
    The Journal of pharmacy and pharmacology, 2023, Jul-05, Volume: 75, Issue:7

    Topics: Acetone; Brain Neoplasms; Cell Line, Tumor; Ethanol; Glioblastoma; Humans; Nanoparticles; Serum Albu

2023
The interplay of solvent-drug-protein interactions during albumin nanoparticles formulations for temozolomide delivery to brain cancer cells.
    The Journal of pharmacy and pharmacology, 2023, Jul-05, Volume: 75, Issue:7

    Topics: Acetone; Brain Neoplasms; Cell Line, Tumor; Ethanol; Glioblastoma; Humans; Nanoparticles; Serum Albu

2023
Identification of the E2F1-RAD51AP1 axis as a key factor in MGMT-methylated GBM TMZ resistance.
    Cancer biology & medicine, 2023, 06-05, Volume: 20, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; E2F1 Transcription Factor; Glioblastoma; Glioma;

2023
Identification of the E2F1-RAD51AP1 axis as a key factor in MGMT-methylated GBM TMZ resistance.
    Cancer biology & medicine, 2023, 06-05, Volume: 20, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; E2F1 Transcription Factor; Glioblastoma; Glioma;

2023
Identification of the E2F1-RAD51AP1 axis as a key factor in MGMT-methylated GBM TMZ resistance.
    Cancer biology & medicine, 2023, 06-05, Volume: 20, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; E2F1 Transcription Factor; Glioblastoma; Glioma;

2023
4-Methylumbelliferone enhances the effects of chemotherapy on both temozolomide-sensitive and resistant glioblastoma cells.
    Scientific reports, 2023, 06-08, Volume: 13, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation;

2023
4-Methylumbelliferone enhances the effects of chemotherapy on both temozolomide-sensitive and resistant glioblastoma cells.
    Scientific reports, 2023, 06-08, Volume: 13, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation;

2023
4-Methylumbelliferone enhances the effects of chemotherapy on both temozolomide-sensitive and resistant glioblastoma cells.
    Scientific reports, 2023, 06-08, Volume: 13, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation;

2023
Insights into Gene Regulation under Temozolomide-Promoted Cellular Dormancy and Its Connection to Stemness in Human Glioblastoma.
    Cells, 2023, May-27, Volume: 12, Issue:11

    Topics: Brain Neoplasms; Cell Line, Tumor; Gene Expression Regulation, Neoplastic; Glioblastoma; Humans; Tem

2023
Insights into Gene Regulation under Temozolomide-Promoted Cellular Dormancy and Its Connection to Stemness in Human Glioblastoma.
    Cells, 2023, May-27, Volume: 12, Issue:11

    Topics: Brain Neoplasms; Cell Line, Tumor; Gene Expression Regulation, Neoplastic; Glioblastoma; Humans; Tem

2023
Insights into Gene Regulation under Temozolomide-Promoted Cellular Dormancy and Its Connection to Stemness in Human Glioblastoma.
    Cells, 2023, May-27, Volume: 12, Issue:11

    Topics: Brain Neoplasms; Cell Line, Tumor; Gene Expression Regulation, Neoplastic; Glioblastoma; Humans; Tem

2023
Exploring the Functional Roles of Telomere Maintenance 2 in the Tumorigenesis of Glioblastoma Multiforme and Drug Responsiveness to Temozolomide.
    International journal of molecular sciences, 2023, May-25, Volume: 24, Issue:11

    Topics: Adult; Antineoplastic Agents, Alkylating; Brain Neoplasms; Carcinogenesis; Cell Line, Tumor; Cell Tr

2023
Exploring the Functional Roles of Telomere Maintenance 2 in the Tumorigenesis of Glioblastoma Multiforme and Drug Responsiveness to Temozolomide.
    International journal of molecular sciences, 2023, May-25, Volume: 24, Issue:11

    Topics: Adult; Antineoplastic Agents, Alkylating; Brain Neoplasms; Carcinogenesis; Cell Line, Tumor; Cell Tr

2023
Exploring the Functional Roles of Telomere Maintenance 2 in the Tumorigenesis of Glioblastoma Multiforme and Drug Responsiveness to Temozolomide.
    International journal of molecular sciences, 2023, May-25, Volume: 24, Issue:11

    Topics: Adult; Antineoplastic Agents, Alkylating; Brain Neoplasms; Carcinogenesis; Cell Line, Tumor; Cell Tr

2023
Resveratrol Enhances Temozolomide Efficacy in Glioblastoma Cells through Downregulated MGMT and Negative Regulators-Related STAT3 Inactivation.
    International journal of molecular sciences, 2023, May-29, Volume: 24, Issue:11

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; DNA Modification Methylases; D

2023
Resveratrol Enhances Temozolomide Efficacy in Glioblastoma Cells through Downregulated MGMT and Negative Regulators-Related STAT3 Inactivation.
    International journal of molecular sciences, 2023, May-29, Volume: 24, Issue:11

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; DNA Modification Methylases; D

2023
Resveratrol Enhances Temozolomide Efficacy in Glioblastoma Cells through Downregulated MGMT and Negative Regulators-Related STAT3 Inactivation.
    International journal of molecular sciences, 2023, May-29, Volume: 24, Issue:11

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; DNA Modification Methylases; D

2023
HOXD-AS2-STAT3 feedback loop attenuates sensitivity to temozolomide in glioblastoma.
    CNS neuroscience & therapeutics, 2023, Volume: 29, Issue:11

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; Fee

2023
HOXD-AS2-STAT3 feedback loop attenuates sensitivity to temozolomide in glioblastoma.
    CNS neuroscience & therapeutics, 2023, Volume: 29, Issue:11

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; Fee

2023
HOXD-AS2-STAT3 feedback loop attenuates sensitivity to temozolomide in glioblastoma.
    CNS neuroscience & therapeutics, 2023, Volume: 29, Issue:11

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; Fee

2023
Utility of Comprehensive Genomic Profiling for Precise Diagnosis of Pediatric-Type Diffuse High-Grade Glioma.
    Acta medica Okayama, 2023, Volume: 77, Issue:3

    Topics: Adolescent; Brain Neoplasms; Child; Genomics; Glioma; Humans; Male; Mutation; Temozolomide

2023
Utility of Comprehensive Genomic Profiling for Precise Diagnosis of Pediatric-Type Diffuse High-Grade Glioma.
    Acta medica Okayama, 2023, Volume: 77, Issue:3

    Topics: Adolescent; Brain Neoplasms; Child; Genomics; Glioma; Humans; Male; Mutation; Temozolomide

2023
Utility of Comprehensive Genomic Profiling for Precise Diagnosis of Pediatric-Type Diffuse High-Grade Glioma.
    Acta medica Okayama, 2023, Volume: 77, Issue:3

    Topics: Adolescent; Brain Neoplasms; Child; Genomics; Glioma; Humans; Male; Mutation; Temozolomide

2023
The Impact of O6-Methylguanine-DNA Methyltransferase (
    Cells, 2023, 06-15, Volume: 12, Issue:12

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; DNA; DNA Methylation; DNA Modificat

2023
The Impact of O6-Methylguanine-DNA Methyltransferase (
    Cells, 2023, 06-15, Volume: 12, Issue:12

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; DNA; DNA Methylation; DNA Modificat

2023
The Impact of O6-Methylguanine-DNA Methyltransferase (
    Cells, 2023, 06-15, Volume: 12, Issue:12

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; DNA; DNA Methylation; DNA Modificat

2023
Suppression of NANOG Expression Reduces Drug Resistance of Cancer Stem Cells in Glioblastoma.
    Genes, 2023, 06-16, Volume: 14, Issue:6

    Topics: Brain Neoplasms; Cell Line, Tumor; Drug Resistance; Glioblastoma; Humans; Nanog Homeobox Protein; Ne

2023
Suppression of NANOG Expression Reduces Drug Resistance of Cancer Stem Cells in Glioblastoma.
    Genes, 2023, 06-16, Volume: 14, Issue:6

    Topics: Brain Neoplasms; Cell Line, Tumor; Drug Resistance; Glioblastoma; Humans; Nanog Homeobox Protein; Ne

2023
Suppression of NANOG Expression Reduces Drug Resistance of Cancer Stem Cells in Glioblastoma.
    Genes, 2023, 06-16, Volume: 14, Issue:6

    Topics: Brain Neoplasms; Cell Line, Tumor; Drug Resistance; Glioblastoma; Humans; Nanog Homeobox Protein; Ne

2023
Mitochondria Transfer from Mesenchymal Stem Cells Confers Chemoresistance to Glioblastoma Stem Cells through Metabolic Rewiring.
    Cancer research communications, 2023, Volume: 3, Issue:6

    Topics: Brain Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; Glioblastoma; Humans; Mesenchymal Stem

2023
Mitochondria Transfer from Mesenchymal Stem Cells Confers Chemoresistance to Glioblastoma Stem Cells through Metabolic Rewiring.
    Cancer research communications, 2023, Volume: 3, Issue:6

    Topics: Brain Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; Glioblastoma; Humans; Mesenchymal Stem

2023
Mitochondria Transfer from Mesenchymal Stem Cells Confers Chemoresistance to Glioblastoma Stem Cells through Metabolic Rewiring.
    Cancer research communications, 2023, Volume: 3, Issue:6

    Topics: Brain Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; Glioblastoma; Humans; Mesenchymal Stem

2023
[Regional variation in usage of TTF (Optune)].
    Lakartidningen, 2023, 07-03, Volume: 120

    Topics: Brain Neoplasms; Combined Modality Therapy; Glioblastoma; Humans; Temozolomide

2023
[Regional variation in usage of TTF (Optune)].
    Lakartidningen, 2023, 07-03, Volume: 120

    Topics: Brain Neoplasms; Combined Modality Therapy; Glioblastoma; Humans; Temozolomide

2023
[Regional variation in usage of TTF (Optune)].
    Lakartidningen, 2023, 07-03, Volume: 120

    Topics: Brain Neoplasms; Combined Modality Therapy; Glioblastoma; Humans; Temozolomide

2023
The antagonistic effects of temozolomide and trichostatin a combination on MGMT and DNA mismatch repair pathways in Glioblastoma.
    Medical oncology (Northwood, London, England), 2023, Jul-05, Volume: 40, Issue:8

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Dacarbazine; DNA Mismatch Repa

2023
The antagonistic effects of temozolomide and trichostatin a combination on MGMT and DNA mismatch repair pathways in Glioblastoma.
    Medical oncology (Northwood, London, England), 2023, Jul-05, Volume: 40, Issue:8

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Dacarbazine; DNA Mismatch Repa

2023
The antagonistic effects of temozolomide and trichostatin a combination on MGMT and DNA mismatch repair pathways in Glioblastoma.
    Medical oncology (Northwood, London, England), 2023, Jul-05, Volume: 40, Issue:8

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Dacarbazine; DNA Mismatch Repa

2023
Differences in clinical outcomes based on molecular markers in glioblastoma patients treated with concurrent tumor-treating fields and chemoradiation: exploratory analysis of the SPARE trial.
    Chinese clinical oncology, 2023, Volume: 12, Issue:3

    Topics: Adult; Antineoplastic Agents, Alkylating; Biomarkers; Brain Neoplasms; Dacarbazine; DNA Methylation;

2023
Differences in clinical outcomes based on molecular markers in glioblastoma patients treated with concurrent tumor-treating fields and chemoradiation: exploratory analysis of the SPARE trial.
    Chinese clinical oncology, 2023, Volume: 12, Issue:3

    Topics: Adult; Antineoplastic Agents, Alkylating; Biomarkers; Brain Neoplasms; Dacarbazine; DNA Methylation;

2023
Differences in clinical outcomes based on molecular markers in glioblastoma patients treated with concurrent tumor-treating fields and chemoradiation: exploratory analysis of the SPARE trial.
    Chinese clinical oncology, 2023, Volume: 12, Issue:3

    Topics: Adult; Antineoplastic Agents, Alkylating; Biomarkers; Brain Neoplasms; Dacarbazine; DNA Methylation;

2023
Label-Free Raman Spectromicroscopy Unravels the Relationship between MGMT Methylation and Intracellular Lipid Accumulation in Glioblastoma.
    Analytical chemistry, 2023, 08-08, Volume: 95, Issue:31

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; DNA Methylation; DNA Modification M

2023
Label-Free Raman Spectromicroscopy Unravels the Relationship between MGMT Methylation and Intracellular Lipid Accumulation in Glioblastoma.
    Analytical chemistry, 2023, 08-08, Volume: 95, Issue:31

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; DNA Methylation; DNA Modification M

2023
Label-Free Raman Spectromicroscopy Unravels the Relationship between MGMT Methylation and Intracellular Lipid Accumulation in Glioblastoma.
    Analytical chemistry, 2023, 08-08, Volume: 95, Issue:31

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; DNA Methylation; DNA Modification M

2023
A Trojan-Horse-Like Biomimetic Nano-NK to Elicit an Immunostimulatory Tumor Microenvironment for Enhanced GBM Chemo-Immunotherapy.
    Small (Weinheim an der Bergstrasse, Germany), 2023, Volume: 19, Issue:44

    Topics: Animals; Biomimetics; Brain Neoplasms; Cell Line, Tumor; Glioblastoma; Immunotherapy; Interleukin-15

2023
A Trojan-Horse-Like Biomimetic Nano-NK to Elicit an Immunostimulatory Tumor Microenvironment for Enhanced GBM Chemo-Immunotherapy.
    Small (Weinheim an der Bergstrasse, Germany), 2023, Volume: 19, Issue:44

    Topics: Animals; Biomimetics; Brain Neoplasms; Cell Line, Tumor; Glioblastoma; Immunotherapy; Interleukin-15

2023
A Trojan-Horse-Like Biomimetic Nano-NK to Elicit an Immunostimulatory Tumor Microenvironment for Enhanced GBM Chemo-Immunotherapy.
    Small (Weinheim an der Bergstrasse, Germany), 2023, Volume: 19, Issue:44

    Topics: Animals; Biomimetics; Brain Neoplasms; Cell Line, Tumor; Glioblastoma; Immunotherapy; Interleukin-15

2023
Letter: are there incidences of clinically relevant psychiatric symptoms during glioblastoma treatment?
    Journal of neuro-oncology, 2023, Volume: 163, Issue:3

    Topics: Brain Neoplasms; Glioblastoma; Humans; Incidence; Mental Disorders; Temozolomide

2023
Letter: are there incidences of clinically relevant psychiatric symptoms during glioblastoma treatment?
    Journal of neuro-oncology, 2023, Volume: 163, Issue:3

    Topics: Brain Neoplasms; Glioblastoma; Humans; Incidence; Mental Disorders; Temozolomide

2023
Letter: are there incidences of clinically relevant psychiatric symptoms during glioblastoma treatment?
    Journal of neuro-oncology, 2023, Volume: 163, Issue:3

    Topics: Brain Neoplasms; Glioblastoma; Humans; Incidence; Mental Disorders; Temozolomide

2023
Agent-Based Modelling Reveals the Role of the Tumor Microenvironment on the Short-Term Success of Combination Temozolomide/Immune Checkpoint Blockade to Treat Glioblastoma.
    The Journal of pharmacology and experimental therapeutics, 2023, Volume: 387, Issue:1

    Topics: Adult; Antineoplastic Agents; Brain Neoplasms; Glioblastoma; Humans; Immune Checkpoint Inhibitors; I

2023
Agent-Based Modelling Reveals the Role of the Tumor Microenvironment on the Short-Term Success of Combination Temozolomide/Immune Checkpoint Blockade to Treat Glioblastoma.
    The Journal of pharmacology and experimental therapeutics, 2023, Volume: 387, Issue:1

    Topics: Adult; Antineoplastic Agents; Brain Neoplasms; Glioblastoma; Humans; Immune Checkpoint Inhibitors; I

2023
Agent-Based Modelling Reveals the Role of the Tumor Microenvironment on the Short-Term Success of Combination Temozolomide/Immune Checkpoint Blockade to Treat Glioblastoma.
    The Journal of pharmacology and experimental therapeutics, 2023, Volume: 387, Issue:1

    Topics: Adult; Antineoplastic Agents; Brain Neoplasms; Glioblastoma; Humans; Immune Checkpoint Inhibitors; I

2023
Quercetin induces MGMT
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2023, Volume: 118

    Topics: Apoptosis; Apoptosis Regulatory Proteins; beta Catenin; Brain Neoplasms; Cell Line, Tumor; Drug Resi

2023
Quercetin induces MGMT
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2023, Volume: 118

    Topics: Apoptosis; Apoptosis Regulatory Proteins; beta Catenin; Brain Neoplasms; Cell Line, Tumor; Drug Resi

2023
Quercetin induces MGMT
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2023, Volume: 118

    Topics: Apoptosis; Apoptosis Regulatory Proteins; beta Catenin; Brain Neoplasms; Cell Line, Tumor; Drug Resi

2023
Safety and Efficacy of Anlotinib Hydrochloride Plus Temozolomide in Patients with Recurrent Glioblastoma.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2023, 10-02, Volume: 29, Issue:19

    Topics: Adult; Aged; Angiogenesis Inhibitors; Brain Neoplasms; Dacarbazine; Glioblastoma; Humans; Middle Age

2023
Safety and Efficacy of Anlotinib Hydrochloride Plus Temozolomide in Patients with Recurrent Glioblastoma.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2023, 10-02, Volume: 29, Issue:19

    Topics: Adult; Aged; Angiogenesis Inhibitors; Brain Neoplasms; Dacarbazine; Glioblastoma; Humans; Middle Age

2023
Safety and Efficacy of Anlotinib Hydrochloride Plus Temozolomide in Patients with Recurrent Glioblastoma.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2023, 10-02, Volume: 29, Issue:19

    Topics: Adult; Aged; Angiogenesis Inhibitors; Brain Neoplasms; Dacarbazine; Glioblastoma; Humans; Middle Age

2023
Nitric Oxide Prevents Glioblastoma Stem Cells' Expansion and Induces Temozolomide Sensitization.
    International journal of molecular sciences, 2023, Jul-10, Volume: 24, Issue:14

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Cycle; Cell Line, Tumor; Cell Proliferation

2023
Nitric Oxide Prevents Glioblastoma Stem Cells' Expansion and Induces Temozolomide Sensitization.
    International journal of molecular sciences, 2023, Jul-10, Volume: 24, Issue:14

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Cycle; Cell Line, Tumor; Cell Proliferation

2023
Nitric Oxide Prevents Glioblastoma Stem Cells' Expansion and Induces Temozolomide Sensitization.
    International journal of molecular sciences, 2023, Jul-10, Volume: 24, Issue:14

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Cycle; Cell Line, Tumor; Cell Proliferation

2023
Role of SH3GLB1 in the regulation of CD133 expression in GBM cells.
    BMC cancer, 2023, Jul-31, Volume: 23, Issue:1

    Topics: Brain Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; Glioblastoma; Humans; RNA Interference

2023
Role of SH3GLB1 in the regulation of CD133 expression in GBM cells.
    BMC cancer, 2023, Jul-31, Volume: 23, Issue:1

    Topics: Brain Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; Glioblastoma; Humans; RNA Interference

2023
Role of SH3GLB1 in the regulation of CD133 expression in GBM cells.
    BMC cancer, 2023, Jul-31, Volume: 23, Issue:1

    Topics: Brain Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; Glioblastoma; Humans; RNA Interference

2023
TRIB1 confers therapeutic resistance in GBM cells by activating the ERK and Akt pathways.
    Scientific reports, 2023, 08-01, Volume: 13, Issue:1

    Topics: Animals; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; Glioblastoma; Mice

2023
TRIB1 confers therapeutic resistance in GBM cells by activating the ERK and Akt pathways.
    Scientific reports, 2023, 08-01, Volume: 13, Issue:1

    Topics: Animals; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; Glioblastoma; Mice

2023
TRIB1 confers therapeutic resistance in GBM cells by activating the ERK and Akt pathways.
    Scientific reports, 2023, 08-01, Volume: 13, Issue:1

    Topics: Animals; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; Glioblastoma; Mice

2023
The Assessment of Clinical Outcomes and Prognostic Factors in Glioblastoma Patients.
    Turkish neurosurgery, 2023, Volume: 33, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Glioblastoma; Humans; Neoplas

2023
The Assessment of Clinical Outcomes and Prognostic Factors in Glioblastoma Patients.
    Turkish neurosurgery, 2023, Volume: 33, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Glioblastoma; Humans; Neoplas

2023
The Assessment of Clinical Outcomes and Prognostic Factors in Glioblastoma Patients.
    Turkish neurosurgery, 2023, Volume: 33, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Glioblastoma; Humans; Neoplas

2023
Prognostic Value of TSPO PET Before Radiotherapy in Newly Diagnosed IDH-Wild-Type Glioblastoma.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2023, Volume: 64, Issue:10

    Topics: Brain Neoplasms; Glioblastoma; Humans; Isocitrate Dehydrogenase; Middle Aged; Positron-Emission Tomo

2023
Prognostic Value of TSPO PET Before Radiotherapy in Newly Diagnosed IDH-Wild-Type Glioblastoma.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2023, Volume: 64, Issue:10

    Topics: Brain Neoplasms; Glioblastoma; Humans; Isocitrate Dehydrogenase; Middle Aged; Positron-Emission Tomo

2023
Prognostic Value of TSPO PET Before Radiotherapy in Newly Diagnosed IDH-Wild-Type Glioblastoma.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2023, Volume: 64, Issue:10

    Topics: Brain Neoplasms; Glioblastoma; Humans; Isocitrate Dehydrogenase; Middle Aged; Positron-Emission Tomo

2023
FOXO1-miR-506 axis promotes chemosensitivity to temozolomide and suppresses invasiveness in glioblastoma through a feedback loop of FOXO1/miR-506/ETS1/FOXO1.
    Journal of Zhejiang University. Science. B, 2023, Aug-15, Volume: 24, Issue:8

    Topics: Animals; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Drug Resistance, Neoplasm; Feedback;

2023
FOXO1-miR-506 axis promotes chemosensitivity to temozolomide and suppresses invasiveness in glioblastoma through a feedback loop of FOXO1/miR-506/ETS1/FOXO1.
    Journal of Zhejiang University. Science. B, 2023, Aug-15, Volume: 24, Issue:8

    Topics: Animals; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Drug Resistance, Neoplasm; Feedback;

2023
FOXO1-miR-506 axis promotes chemosensitivity to temozolomide and suppresses invasiveness in glioblastoma through a feedback loop of FOXO1/miR-506/ETS1/FOXO1.
    Journal of Zhejiang University. Science. B, 2023, Aug-15, Volume: 24, Issue:8

    Topics: Animals; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Drug Resistance, Neoplasm; Feedback;

2023
Local administration of shikonin improved the overall survival in orthotopic murine glioblastoma models with temozolomide resistance.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2023, Volume: 166

    Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Cell Line, Tumor; Glioblastoma; Humans; Mice; Mice,

2023
Local administration of shikonin improved the overall survival in orthotopic murine glioblastoma models with temozolomide resistance.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2023, Volume: 166

    Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Cell Line, Tumor; Glioblastoma; Humans; Mice; Mice,

2023
Local administration of shikonin improved the overall survival in orthotopic murine glioblastoma models with temozolomide resistance.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2023, Volume: 166

    Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Cell Line, Tumor; Glioblastoma; Humans; Mice; Mice,

2023
Propofol Inhibits Glioma Stem Cell Growth and Migration and Their Interaction with Microglia via BDNF-AS and Extracellular Vesicles.
    Cells, 2023, 07-25, Volume: 12, Issue:15

    Topics: Brain Neoplasms; Brain-Derived Neurotrophic Factor; Extracellular Vesicles; Glioblastoma; Glioma; Hu

2023
Propofol Inhibits Glioma Stem Cell Growth and Migration and Their Interaction with Microglia via BDNF-AS and Extracellular Vesicles.
    Cells, 2023, 07-25, Volume: 12, Issue:15

    Topics: Brain Neoplasms; Brain-Derived Neurotrophic Factor; Extracellular Vesicles; Glioblastoma; Glioma; Hu

2023
Propofol Inhibits Glioma Stem Cell Growth and Migration and Their Interaction with Microglia via BDNF-AS and Extracellular Vesicles.
    Cells, 2023, 07-25, Volume: 12, Issue:15

    Topics: Brain Neoplasms; Brain-Derived Neurotrophic Factor; Extracellular Vesicles; Glioblastoma; Glioma; Hu

2023
Autophagy Inhibition via Hydroxychloroquine or 3-Methyladenine Enhances Chemotherapy-Induced Apoptosis in Neuro-Blastoma and Glioblastoma.
    International journal of molecular sciences, 2023, Jul-27, Volume: 24, Issue:15

    Topics: Antineoplastic Agents; Apoptosis; Autophagy; Brain Neoplasms; Cell Line, Tumor; Child; Cisplatin; Gl

2023
Autophagy Inhibition via Hydroxychloroquine or 3-Methyladenine Enhances Chemotherapy-Induced Apoptosis in Neuro-Blastoma and Glioblastoma.
    International journal of molecular sciences, 2023, Jul-27, Volume: 24, Issue:15

    Topics: Antineoplastic Agents; Apoptosis; Autophagy; Brain Neoplasms; Cell Line, Tumor; Child; Cisplatin; Gl

2023
Autophagy Inhibition via Hydroxychloroquine or 3-Methyladenine Enhances Chemotherapy-Induced Apoptosis in Neuro-Blastoma and Glioblastoma.
    International journal of molecular sciences, 2023, Jul-27, Volume: 24, Issue:15

    Topics: Antineoplastic Agents; Apoptosis; Autophagy; Brain Neoplasms; Cell Line, Tumor; Child; Cisplatin; Gl

2023
Ex vivo drug sensitivity screening predicts response to temozolomide in glioblastoma patients and identifies candidate biomarkers.
    British journal of cancer, 2023, Volume: 129, Issue:8

    Topics: Antineoplastic Agents, Alkylating; Biomarkers; Brain Neoplasms; Cell Line, Tumor; Dacarbazine; DNA;

2023
Ex vivo drug sensitivity screening predicts response to temozolomide in glioblastoma patients and identifies candidate biomarkers.
    British journal of cancer, 2023, Volume: 129, Issue:8

    Topics: Antineoplastic Agents, Alkylating; Biomarkers; Brain Neoplasms; Cell Line, Tumor; Dacarbazine; DNA;

2023
Ex vivo drug sensitivity screening predicts response to temozolomide in glioblastoma patients and identifies candidate biomarkers.
    British journal of cancer, 2023, Volume: 129, Issue:8

    Topics: Antineoplastic Agents, Alkylating; Biomarkers; Brain Neoplasms; Cell Line, Tumor; Dacarbazine; DNA;

2023
Long-term treatment outcomes of temozolomide-based chemoradiation in patients with adult-type diffuse IDH-mutant grade 2 astrocytoma.
    Journal of neuro-oncology, 2023, Volume: 164, Issue:2

    Topics: Adult; Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neoplasms; Dacarbazine; Humans; Temozol

2023
Long-term treatment outcomes of temozolomide-based chemoradiation in patients with adult-type diffuse IDH-mutant grade 2 astrocytoma.
    Journal of neuro-oncology, 2023, Volume: 164, Issue:2

    Topics: Adult; Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neoplasms; Dacarbazine; Humans; Temozol

2023
Long-term treatment outcomes of temozolomide-based chemoradiation in patients with adult-type diffuse IDH-mutant grade 2 astrocytoma.
    Journal of neuro-oncology, 2023, Volume: 164, Issue:2

    Topics: Adult; Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neoplasms; Dacarbazine; Humans; Temozol

2023
5-lipoxygenase as a target to sensitize glioblastoma to temozolomide treatment via β-catenin-dependent pathway.
    Neurological research, 2023, Volume: 45, Issue:11

    Topics: Animals; Arachidonate 5-Lipoxygenase; beta Catenin; Brain Neoplasms; Cell Line, Tumor; Cell Prolifer

2023
5-lipoxygenase as a target to sensitize glioblastoma to temozolomide treatment via β-catenin-dependent pathway.
    Neurological research, 2023, Volume: 45, Issue:11

    Topics: Animals; Arachidonate 5-Lipoxygenase; beta Catenin; Brain Neoplasms; Cell Line, Tumor; Cell Prolifer

2023
5-lipoxygenase as a target to sensitize glioblastoma to temozolomide treatment via β-catenin-dependent pathway.
    Neurological research, 2023, Volume: 45, Issue:11

    Topics: Animals; Arachidonate 5-Lipoxygenase; beta Catenin; Brain Neoplasms; Cell Line, Tumor; Cell Prolifer

2023
Temozolomide-based sonodynamic therapy induces immunogenic cell death in glioma.
    Clinical immunology (Orlando, Fla.), 2023, Volume: 256

    Topics: Apoptosis; Brain Neoplasms; Cell Line, Tumor; Glioblastoma; Glioma; Humans; Immunogenic Cell Death;

2023
Temozolomide-based sonodynamic therapy induces immunogenic cell death in glioma.
    Clinical immunology (Orlando, Fla.), 2023, Volume: 256

    Topics: Apoptosis; Brain Neoplasms; Cell Line, Tumor; Glioblastoma; Glioma; Humans; Immunogenic Cell Death;

2023
Temozolomide-based sonodynamic therapy induces immunogenic cell death in glioma.
    Clinical immunology (Orlando, Fla.), 2023, Volume: 256

    Topics: Apoptosis; Brain Neoplasms; Cell Line, Tumor; Glioblastoma; Glioma; Humans; Immunogenic Cell Death;

2023
Undetected pseudoprogressions in the CeTeG/NOA-09 trial: hints from postprogression survival and MRI analyses.
    Journal of neuro-oncology, 2023, Volume: 164, Issue:3

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Glioblastoma; Humans; Lomustine; Ma

2023
Undetected pseudoprogressions in the CeTeG/NOA-09 trial: hints from postprogression survival and MRI analyses.
    Journal of neuro-oncology, 2023, Volume: 164, Issue:3

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Glioblastoma; Humans; Lomustine; Ma

2023
Undetected pseudoprogressions in the CeTeG/NOA-09 trial: hints from postprogression survival and MRI analyses.
    Journal of neuro-oncology, 2023, Volume: 164, Issue:3

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Glioblastoma; Humans; Lomustine; Ma

2023
NFYB increases chemosensitivity in glioblastoma by promoting HDAC5-mediated transcriptional inhibition of SHMT2.
    Journal of neuropathology and experimental neurology, 2023, 10-20, Volume: 82, Issue:11

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; CCAAT-Binding Factor; Cell Line, Tumor; Cell Pro

2023
NFYB increases chemosensitivity in glioblastoma by promoting HDAC5-mediated transcriptional inhibition of SHMT2.
    Journal of neuropathology and experimental neurology, 2023, 10-20, Volume: 82, Issue:11

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; CCAAT-Binding Factor; Cell Line, Tumor; Cell Pro

2023
NFYB increases chemosensitivity in glioblastoma by promoting HDAC5-mediated transcriptional inhibition of SHMT2.
    Journal of neuropathology and experimental neurology, 2023, 10-20, Volume: 82, Issue:11

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; CCAAT-Binding Factor; Cell Line, Tumor; Cell Pro

2023
Identifying predictors of glioma evolution from longitudinal sequencing.
    Science translational medicine, 2023, Oct-04, Volume: 15, Issue:716

    Topics: Adult; Brain Neoplasms; Glioma; Humans; Mutation; Neoplasm Recurrence, Local; Precision Medicine; Te

2023
Identifying predictors of glioma evolution from longitudinal sequencing.
    Science translational medicine, 2023, Oct-04, Volume: 15, Issue:716

    Topics: Adult; Brain Neoplasms; Glioma; Humans; Mutation; Neoplasm Recurrence, Local; Precision Medicine; Te

2023
Identifying predictors of glioma evolution from longitudinal sequencing.
    Science translational medicine, 2023, Oct-04, Volume: 15, Issue:716

    Topics: Adult; Brain Neoplasms; Glioma; Humans; Mutation; Neoplasm Recurrence, Local; Precision Medicine; Te

2023
Effect of Temozolomide Combined with Intensity Modulated Radiation Therapy on Serum Factor, Immune Function and Clinical Efficacy in Postoperative Glioma Patients.
    Radiation research, 2023, 09-01, Volume: 200, Issue:3

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Glioma; Humans; Immunity; Temozolomide; Treatmen

2023
Effect of Temozolomide Combined with Intensity Modulated Radiation Therapy on Serum Factor, Immune Function and Clinical Efficacy in Postoperative Glioma Patients.
    Radiation research, 2023, 09-01, Volume: 200, Issue:3

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Glioma; Humans; Immunity; Temozolomide; Treatmen

2023
Effect of Temozolomide Combined with Intensity Modulated Radiation Therapy on Serum Factor, Immune Function and Clinical Efficacy in Postoperative Glioma Patients.
    Radiation research, 2023, 09-01, Volume: 200, Issue:3

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Glioma; Humans; Immunity; Temozolomide; Treatmen

2023
Epigenomic perturbation of novel EGFR enhancers reduces the proliferative and invasive capacity of glioblastoma and increases sensitivity to temozolomide.
    BMC cancer, 2023, Oct-06, Volume: 23, Issue:1

    Topics: Brain Neoplasms; Cell Line, Tumor; Epigenomics; ErbB Receptors; Genes, erbB-1; Glioblastoma; Humans;

2023
Epigenomic perturbation of novel EGFR enhancers reduces the proliferative and invasive capacity of glioblastoma and increases sensitivity to temozolomide.
    BMC cancer, 2023, Oct-06, Volume: 23, Issue:1

    Topics: Brain Neoplasms; Cell Line, Tumor; Epigenomics; ErbB Receptors; Genes, erbB-1; Glioblastoma; Humans;

2023
Epigenomic perturbation of novel EGFR enhancers reduces the proliferative and invasive capacity of glioblastoma and increases sensitivity to temozolomide.
    BMC cancer, 2023, Oct-06, Volume: 23, Issue:1

    Topics: Brain Neoplasms; Cell Line, Tumor; Epigenomics; ErbB Receptors; Genes, erbB-1; Glioblastoma; Humans;

2023
The effect of chemotherapies on the crosstalk interaction between CD8 cytotoxic T-cells and MHC-I peptides in the microenvironment of WHO grade 4 astrocytoma.
    Folia neuropathologica, 2023, Volume: 61, Issue:3

    Topics: Astrocytoma; Brain Neoplasms; CD8-Positive T-Lymphocytes; Glioblastoma; Histocompatibility Antigens

2023
The effect of chemotherapies on the crosstalk interaction between CD8 cytotoxic T-cells and MHC-I peptides in the microenvironment of WHO grade 4 astrocytoma.
    Folia neuropathologica, 2023, Volume: 61, Issue:3

    Topics: Astrocytoma; Brain Neoplasms; CD8-Positive T-Lymphocytes; Glioblastoma; Histocompatibility Antigens

2023
The effect of chemotherapies on the crosstalk interaction between CD8 cytotoxic T-cells and MHC-I peptides in the microenvironment of WHO grade 4 astrocytoma.
    Folia neuropathologica, 2023, Volume: 61, Issue:3

    Topics: Astrocytoma; Brain Neoplasms; CD8-Positive T-Lymphocytes; Glioblastoma; Histocompatibility Antigens

2023
Development and characterization of a temozolomide-loaded nanoemulsion and the effect of ferrocene pre and co-treatments in glioblastoma cell models.
    Pharmacological reports : PR, 2023, Volume: 75, Issue:6

    Topics: Brain Neoplasms; Cell Line, Tumor; Glioblastoma; Humans; Metallocenes; Reactive Oxygen Species; Temo

2023
Development and characterization of a temozolomide-loaded nanoemulsion and the effect of ferrocene pre and co-treatments in glioblastoma cell models.
    Pharmacological reports : PR, 2023, Volume: 75, Issue:6

    Topics: Brain Neoplasms; Cell Line, Tumor; Glioblastoma; Humans; Metallocenes; Reactive Oxygen Species; Temo

2023
Development and characterization of a temozolomide-loaded nanoemulsion and the effect of ferrocene pre and co-treatments in glioblastoma cell models.
    Pharmacological reports : PR, 2023, Volume: 75, Issue:6

    Topics: Brain Neoplasms; Cell Line, Tumor; Glioblastoma; Humans; Metallocenes; Reactive Oxygen Species; Temo

2023
Comparative Analysis of IDH Wild-Type Multifocal and Unifocal Glioblastomas: Prognostic Factors and Survival Outcomes in Focus.
    Turkish neurosurgery, 2023, Volume: 33, Issue:6

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Female; Glioblastoma; Humans; Male; Middle Aged;

2023
Comparative Analysis of IDH Wild-Type Multifocal and Unifocal Glioblastomas: Prognostic Factors and Survival Outcomes in Focus.
    Turkish neurosurgery, 2023, Volume: 33, Issue:6

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Female; Glioblastoma; Humans; Male; Middle Aged;

2023
Comparative Analysis of IDH Wild-Type Multifocal and Unifocal Glioblastomas: Prognostic Factors and Survival Outcomes in Focus.
    Turkish neurosurgery, 2023, Volume: 33, Issue:6

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Female; Glioblastoma; Humans; Male; Middle Aged;

2023
A novel strategy to increase the therapeutic potency of GBM chemotherapy via altering parenchymal/cerebral spinal fluid clearance rate.
    Journal of controlled release : official journal of the Controlled Release Society, 2023, Volume: 364

    Topics: Animals; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Brain Ne

2023
A novel strategy to increase the therapeutic potency of GBM chemotherapy via altering parenchymal/cerebral spinal fluid clearance rate.
    Journal of controlled release : official journal of the Controlled Release Society, 2023, Volume: 364

    Topics: Animals; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Brain Ne

2023
A novel strategy to increase the therapeutic potency of GBM chemotherapy via altering parenchymal/cerebral spinal fluid clearance rate.
    Journal of controlled release : official journal of the Controlled Release Society, 2023, Volume: 364

    Topics: Animals; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Brain Ne

2023
Human cerebrospinal fluid affects chemoradiotherapy sensitivities in tumor cells from patients with glioblastoma.
    Science advances, 2023, 10-27, Volume: 9, Issue:43

    Topics: Brain Neoplasms; Cell Line, Tumor; Chemoradiotherapy; Glioblastoma; Humans; Temozolomide; Trifluoper

2023
Human cerebrospinal fluid affects chemoradiotherapy sensitivities in tumor cells from patients with glioblastoma.
    Science advances, 2023, 10-27, Volume: 9, Issue:43

    Topics: Brain Neoplasms; Cell Line, Tumor; Chemoradiotherapy; Glioblastoma; Humans; Temozolomide; Trifluoper

2023
Human cerebrospinal fluid affects chemoradiotherapy sensitivities in tumor cells from patients with glioblastoma.
    Science advances, 2023, 10-27, Volume: 9, Issue:43

    Topics: Brain Neoplasms; Cell Line, Tumor; Chemoradiotherapy; Glioblastoma; Humans; Temozolomide; Trifluoper

2023
Progesterone Receptor Membrane Component 1 (PGRMC1) Modulates Tumour Progression, the Immune Microenvironment and the Response to Therapy in Glioblastoma.
    Cells, 2023, 10-20, Volume: 12, Issue:20

    Topics: Brain Neoplasms; Glioblastoma; Humans; Membrane Proteins; Neoplastic Processes; Receptors, Progester

2023
Progesterone Receptor Membrane Component 1 (PGRMC1) Modulates Tumour Progression, the Immune Microenvironment and the Response to Therapy in Glioblastoma.
    Cells, 2023, 10-20, Volume: 12, Issue:20

    Topics: Brain Neoplasms; Glioblastoma; Humans; Membrane Proteins; Neoplastic Processes; Receptors, Progester

2023
Progesterone Receptor Membrane Component 1 (PGRMC1) Modulates Tumour Progression, the Immune Microenvironment and the Response to Therapy in Glioblastoma.
    Cells, 2023, 10-20, Volume: 12, Issue:20

    Topics: Brain Neoplasms; Glioblastoma; Humans; Membrane Proteins; Neoplastic Processes; Receptors, Progester

2023
Albumin-bound paclitaxel augment temozolomide treatment sensitivity of glioblastoma cells by disrupting DNA damage repair and promoting ferroptosis.
    Journal of experimental & clinical cancer research : CR, 2023, Oct-28, Volume: 42, Issue:1

    Topics: Albumin-Bound Paclitaxel; Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tu

2023
Albumin-bound paclitaxel augment temozolomide treatment sensitivity of glioblastoma cells by disrupting DNA damage repair and promoting ferroptosis.
    Journal of experimental & clinical cancer research : CR, 2023, Oct-28, Volume: 42, Issue:1

    Topics: Albumin-Bound Paclitaxel; Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tu

2023
Albumin-bound paclitaxel augment temozolomide treatment sensitivity of glioblastoma cells by disrupting DNA damage repair and promoting ferroptosis.
    Journal of experimental & clinical cancer research : CR, 2023, Oct-28, Volume: 42, Issue:1

    Topics: Albumin-Bound Paclitaxel; Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tu

2023
Epigenetic Activation of TUSC3 Sensitizes Glioblastoma to Temozolomide Independent of MGMT Promoter Methylation Status.
    International journal of molecular sciences, 2023, Oct-14, Volume: 24, Issue:20

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Dacarbazine; DNA Methylation;

2023
Epigenetic Activation of TUSC3 Sensitizes Glioblastoma to Temozolomide Independent of MGMT Promoter Methylation Status.
    International journal of molecular sciences, 2023, Oct-14, Volume: 24, Issue:20

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Dacarbazine; DNA Methylation;

2023
Epigenetic Activation of TUSC3 Sensitizes Glioblastoma to Temozolomide Independent of MGMT Promoter Methylation Status.
    International journal of molecular sciences, 2023, Oct-14, Volume: 24, Issue:20

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Dacarbazine; DNA Methylation;

2023
Ceramide Is Involved in Temozolomide Resistance in Human Glioblastoma U87MG Overexpressing EGFR.
    International journal of molecular sciences, 2023, Oct-20, Volume: 24, Issue:20

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Ceramides; Drug Resistance, Ne

2023
Ceramide Is Involved in Temozolomide Resistance in Human Glioblastoma U87MG Overexpressing EGFR.
    International journal of molecular sciences, 2023, Oct-20, Volume: 24, Issue:20

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Ceramides; Drug Resistance, Ne

2023
Ceramide Is Involved in Temozolomide Resistance in Human Glioblastoma U87MG Overexpressing EGFR.
    International journal of molecular sciences, 2023, Oct-20, Volume: 24, Issue:20

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Ceramides; Drug Resistance, Ne

2023
Decreased eukaryotic initiation factors expression upon temozolomide treatment-potential novel implications for eIFs in glioma therapy.
    Journal of neuro-oncology, 2023, Volume: 165, Issue:1

    Topics: Brain Neoplasms; Cell Line, Tumor; Dacarbazine; Glioblastoma; Glioma; Humans; Phosphatidylinositol 3

2023
Decreased eukaryotic initiation factors expression upon temozolomide treatment-potential novel implications for eIFs in glioma therapy.
    Journal of neuro-oncology, 2023, Volume: 165, Issue:1

    Topics: Brain Neoplasms; Cell Line, Tumor; Dacarbazine; Glioblastoma; Glioma; Humans; Phosphatidylinositol 3

2023
Decreased eukaryotic initiation factors expression upon temozolomide treatment-potential novel implications for eIFs in glioma therapy.
    Journal of neuro-oncology, 2023, Volume: 165, Issue:1

    Topics: Brain Neoplasms; Cell Line, Tumor; Dacarbazine; Glioblastoma; Glioma; Humans; Phosphatidylinositol 3

2023
Targeting the non-coding genome and temozolomide signature enables CRISPR-mediated glioma oncolysis.
    Cell reports, 2023, Nov-28, Volume: 42, Issue:11

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; Gli

2023
Targeting the non-coding genome and temozolomide signature enables CRISPR-mediated glioma oncolysis.
    Cell reports, 2023, Nov-28, Volume: 42, Issue:11

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; Gli

2023
Targeting the non-coding genome and temozolomide signature enables CRISPR-mediated glioma oncolysis.
    Cell reports, 2023, Nov-28, Volume: 42, Issue:11

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; Gli

2023
Genomic characterization of IDH-mutant astrocytoma progression to grade 4 in the treatment setting.
    Acta neuropathologica communications, 2023, 11-06, Volume: 11, Issue:1

    Topics: Astrocytoma; Brain Neoplasms; Genomics; Glioma; Humans; Isocitrate Dehydrogenase; Mutation; Retrospe

2023
Genomic characterization of IDH-mutant astrocytoma progression to grade 4 in the treatment setting.
    Acta neuropathologica communications, 2023, 11-06, Volume: 11, Issue:1

    Topics: Astrocytoma; Brain Neoplasms; Genomics; Glioma; Humans; Isocitrate Dehydrogenase; Mutation; Retrospe

2023
Genomic characterization of IDH-mutant astrocytoma progression to grade 4 in the treatment setting.
    Acta neuropathologica communications, 2023, 11-06, Volume: 11, Issue:1

    Topics: Astrocytoma; Brain Neoplasms; Genomics; Glioma; Humans; Isocitrate Dehydrogenase; Mutation; Retrospe

2023
[Curcumol reverses temozolomide resistance in glioma cells by regulating the UTX/MGMT axis].
    Nan fang yi ke da xue xue bao = Journal of Southern Medical University, 2023, Oct-20, Volume: 43, Issue:10

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; DNA Modification Meth

2023
[Curcumol reverses temozolomide resistance in glioma cells by regulating the UTX/MGMT axis].
    Nan fang yi ke da xue xue bao = Journal of Southern Medical University, 2023, Oct-20, Volume: 43, Issue:10

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; DNA Modification Meth

2023
[Curcumol reverses temozolomide resistance in glioma cells by regulating the UTX/MGMT axis].
    Nan fang yi ke da xue xue bao = Journal of Southern Medical University, 2023, Oct-20, Volume: 43, Issue:10

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; DNA Modification Meth

2023
Responses to systemic therapy in metastatic pheochromocytoma/paraganglioma: a retrospective multicenter cohort study.
    European journal of endocrinology, 2023, Nov-08, Volume: 189, Issue:5

    Topics: Adrenal Gland Neoplasms; Brain Neoplasms; Cardiovascular Diseases; Cohort Studies; Humans; Iodine Ra

2023
Responses to systemic therapy in metastatic pheochromocytoma/paraganglioma: a retrospective multicenter cohort study.
    European journal of endocrinology, 2023, Nov-08, Volume: 189, Issue:5

    Topics: Adrenal Gland Neoplasms; Brain Neoplasms; Cardiovascular Diseases; Cohort Studies; Humans; Iodine Ra

2023
Responses to systemic therapy in metastatic pheochromocytoma/paraganglioma: a retrospective multicenter cohort study.
    European journal of endocrinology, 2023, Nov-08, Volume: 189, Issue:5

    Topics: Adrenal Gland Neoplasms; Brain Neoplasms; Cardiovascular Diseases; Cohort Studies; Humans; Iodine Ra

2023
Genomic Exploration of Distinct Molecular Phenotypes Steering Temozolomide Resistance Development in Patient-Derived Glioblastoma Cells.
    International journal of molecular sciences, 2023, Oct-27, Volume: 24, Issue:21

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Dacarbazine; Drug Resistance,

2023
Genomic Exploration of Distinct Molecular Phenotypes Steering Temozolomide Resistance Development in Patient-Derived Glioblastoma Cells.
    International journal of molecular sciences, 2023, Oct-27, Volume: 24, Issue:21

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Dacarbazine; Drug Resistance,

2023
Genomic Exploration of Distinct Molecular Phenotypes Steering Temozolomide Resistance Development in Patient-Derived Glioblastoma Cells.
    International journal of molecular sciences, 2023, Oct-27, Volume: 24, Issue:21

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Dacarbazine; Drug Resistance,

2023
CREB-induced LINC00473 promotes chemoresistance to TMZ in glioblastoma by regulating O6-methylguanine-DNA-methyltransferase expression via CEBPα binding.
    Neuropharmacology, 2024, Feb-01, Volume: 243

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; DNA; DNA Modification Methylas

2024
CREB-induced LINC00473 promotes chemoresistance to TMZ in glioblastoma by regulating O6-methylguanine-DNA-methyltransferase expression via CEBPα binding.
    Neuropharmacology, 2024, Feb-01, Volume: 243

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; DNA; DNA Modification Methylas

2024
CREB-induced LINC00473 promotes chemoresistance to TMZ in glioblastoma by regulating O6-methylguanine-DNA-methyltransferase expression via CEBPα binding.
    Neuropharmacology, 2024, Feb-01, Volume: 243

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; DNA; DNA Modification Methylas

2024
Overcoming chemotherapy resistance in low-grade gliomas: A computational approach.
    PLoS computational biology, 2023, Volume: 19, Issue:11

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Glioma; Humans; Temozolomide

2023
Overcoming chemotherapy resistance in low-grade gliomas: A computational approach.
    PLoS computational biology, 2023, Volume: 19, Issue:11

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Glioma; Humans; Temozolomide

2023
Overcoming chemotherapy resistance in low-grade gliomas: A computational approach.
    PLoS computational biology, 2023, Volume: 19, Issue:11

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Glioma; Humans; Temozolomide

2023
RPL22L1, a novel candidate oncogene promotes temozolomide resistance by activating STAT3 in glioblastoma.
    Cell death & disease, 2023, Nov-20, Volume: 14, Issue:11

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; Gli

2023
RPL22L1, a novel candidate oncogene promotes temozolomide resistance by activating STAT3 in glioblastoma.
    Cell death & disease, 2023, Nov-20, Volume: 14, Issue:11

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; Gli

2023
RPL22L1, a novel candidate oncogene promotes temozolomide resistance by activating STAT3 in glioblastoma.
    Cell death & disease, 2023, Nov-20, Volume: 14, Issue:11

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; Gli

2023
Treatment of glioblastoma in Greenlandic patients.
    International journal of circumpolar health, 2023, Volume: 82, Issue:1

    Topics: Adult; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant; Dacarbazine; Glio

2023
Treatment of glioblastoma in Greenlandic patients.
    International journal of circumpolar health, 2023, Volume: 82, Issue:1

    Topics: Adult; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant; Dacarbazine; Glio

2023
Treatment of glioblastoma in Greenlandic patients.
    International journal of circumpolar health, 2023, Volume: 82, Issue:1

    Topics: Adult; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant; Dacarbazine; Glio

2023
Identification of CDK1, PBK, and CHEK1 as an Oncogenic Signature in Glioblastoma: A Bioinformatics Approach to Repurpose Dapagliflozin as a Therapeutic Agent.
    International journal of molecular sciences, 2023, Nov-16, Volume: 24, Issue:22

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; CDC2 Protein Kinase; Cell Line, Tumor; Checkpoin

2023
Identification of CDK1, PBK, and CHEK1 as an Oncogenic Signature in Glioblastoma: A Bioinformatics Approach to Repurpose Dapagliflozin as a Therapeutic Agent.
    International journal of molecular sciences, 2023, Nov-16, Volume: 24, Issue:22

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; CDC2 Protein Kinase; Cell Line, Tumor; Checkpoin

2023
Identification of CDK1, PBK, and CHEK1 as an Oncogenic Signature in Glioblastoma: A Bioinformatics Approach to Repurpose Dapagliflozin as a Therapeutic Agent.
    International journal of molecular sciences, 2023, Nov-16, Volume: 24, Issue:22

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; CDC2 Protein Kinase; Cell Line, Tumor; Checkpoin

2023
Identification of potential glioma drug resistance target proteins based on ultra-performance liquid chromatography-mass spectrometry differential proteomics.
    PeerJ, 2023, Volume: 11

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Chromatography, Liquid; Dacarb

2023
Identification of potential glioma drug resistance target proteins based on ultra-performance liquid chromatography-mass spectrometry differential proteomics.
    PeerJ, 2023, Volume: 11

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Chromatography, Liquid; Dacarb

2023
Identification of potential glioma drug resistance target proteins based on ultra-performance liquid chromatography-mass spectrometry differential proteomics.
    PeerJ, 2023, Volume: 11

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Chromatography, Liquid; Dacarb

2023
miR-140 targeting CTSB signaling suppresses the mesenchymal transition and enhances temozolomide cytotoxicity in glioblastoma multiforme.
    Pharmacological research, 2019, Volume: 147

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cathepsin B; Cell Line, Tumor; Cell Survival; Do

2019
miR-140 targeting CTSB signaling suppresses the mesenchymal transition and enhances temozolomide cytotoxicity in glioblastoma multiforme.
    Pharmacological research, 2019, Volume: 147

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cathepsin B; Cell Line, Tumor; Cell Survival; Do

2019
miR-140 targeting CTSB signaling suppresses the mesenchymal transition and enhances temozolomide cytotoxicity in glioblastoma multiforme.
    Pharmacological research, 2019, Volume: 147

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cathepsin B; Cell Line, Tumor; Cell Survival; Do

2019
Casein kinase 2 inhibition sensitizes medulloblastoma to temozolomide.
    Oncogene, 2019, Volume: 38, Issue:42

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Casein Kinase II; Enzyme Inhibitors; Humans; Med

2019
Casein kinase 2 inhibition sensitizes medulloblastoma to temozolomide.
    Oncogene, 2019, Volume: 38, Issue:42

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Casein Kinase II; Enzyme Inhibitors; Humans; Med

2019
Casein kinase 2 inhibition sensitizes medulloblastoma to temozolomide.
    Oncogene, 2019, Volume: 38, Issue:42

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Casein Kinase II; Enzyme Inhibitors; Humans; Med

2019
MicroRNA-302c enhances the chemosensitivity of human glioma cells to temozolomide by suppressing P-gp expression.
    Bioscience reports, 2019, 09-30, Volume: 39, Issue:9

    Topics: Antineoplastic Agents, Alkylating; ATP Binding Cassette Transporter, Subfamily B, Member 1; Brain Ne

2019
MicroRNA-302c enhances the chemosensitivity of human glioma cells to temozolomide by suppressing P-gp expression.
    Bioscience reports, 2019, 09-30, Volume: 39, Issue:9

    Topics: Antineoplastic Agents, Alkylating; ATP Binding Cassette Transporter, Subfamily B, Member 1; Brain Ne

2019
MicroRNA-302c enhances the chemosensitivity of human glioma cells to temozolomide by suppressing P-gp expression.
    Bioscience reports, 2019, 09-30, Volume: 39, Issue:9

    Topics: Antineoplastic Agents, Alkylating; ATP Binding Cassette Transporter, Subfamily B, Member 1; Brain Ne

2019
Bortezomib administered prior to temozolomide depletes MGMT, chemosensitizes glioblastoma with unmethylated MGMT promoter and prolongs animal survival.
    British journal of cancer, 2019, Volume: 121, Issue:7

    Topics: Animals; Antineoplastic Agents; Bortezomib; Brain Neoplasms; Cell Line, Tumor; Drug Administration S

2019
Bortezomib administered prior to temozolomide depletes MGMT, chemosensitizes glioblastoma with unmethylated MGMT promoter and prolongs animal survival.
    British journal of cancer, 2019, Volume: 121, Issue:7

    Topics: Animals; Antineoplastic Agents; Bortezomib; Brain Neoplasms; Cell Line, Tumor; Drug Administration S

2019
Bortezomib administered prior to temozolomide depletes MGMT, chemosensitizes glioblastoma with unmethylated MGMT promoter and prolongs animal survival.
    British journal of cancer, 2019, Volume: 121, Issue:7

    Topics: Animals; Antineoplastic Agents; Bortezomib; Brain Neoplasms; Cell Line, Tumor; Drug Administration S

2019
WHO grade has no prognostic value in the pediatric high-grade glioma included in the HERBY trial.
    Neuro-oncology, 2020, 01-11, Volume: 22, Issue:1

    Topics: Adolescent; Antineoplastic Agents; Bevacizumab; Brain Neoplasms; Chemoradiotherapy; Child; Child, Pr

2020
WHO grade has no prognostic value in the pediatric high-grade glioma included in the HERBY trial.
    Neuro-oncology, 2020, 01-11, Volume: 22, Issue:1

    Topics: Adolescent; Antineoplastic Agents; Bevacizumab; Brain Neoplasms; Chemoradiotherapy; Child; Child, Pr

2020
WHO grade has no prognostic value in the pediatric high-grade glioma included in the HERBY trial.
    Neuro-oncology, 2020, 01-11, Volume: 22, Issue:1

    Topics: Adolescent; Antineoplastic Agents; Bevacizumab; Brain Neoplasms; Chemoradiotherapy; Child; Child, Pr

2020
Correlation of the quantitative level of MGMT promoter methylation and overall survival in primary diagnosed glioblastomas using the quantitative MethyQESD method.
    Journal of clinical pathology, 2020, Volume: 73, Issue:2

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Biomarkers, Tumor; Brain Neoplasms; DNA Methylation;

2020
Correlation of the quantitative level of MGMT promoter methylation and overall survival in primary diagnosed glioblastomas using the quantitative MethyQESD method.
    Journal of clinical pathology, 2020, Volume: 73, Issue:2

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Biomarkers, Tumor; Brain Neoplasms; DNA Methylation;

2020
Correlation of the quantitative level of MGMT promoter methylation and overall survival in primary diagnosed glioblastomas using the quantitative MethyQESD method.
    Journal of clinical pathology, 2020, Volume: 73, Issue:2

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Biomarkers, Tumor; Brain Neoplasms; DNA Methylation;

2020
Dehydroabietylamine Ureas and Thioureas as Tyrosyl-DNA Phosphodiesterase 1 Inhibitors That Enhance the Antitumor Effect of Temozolomide on Glioblastoma Cells.
    Journal of natural products, 2019, 09-27, Volume: 82, Issue:9

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; DNA, Neoplasm; Drug Synergism;

2019
Dehydroabietylamine Ureas and Thioureas as Tyrosyl-DNA Phosphodiesterase 1 Inhibitors That Enhance the Antitumor Effect of Temozolomide on Glioblastoma Cells.
    Journal of natural products, 2019, 09-27, Volume: 82, Issue:9

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; DNA, Neoplasm; Drug Synergism;

2019
Dehydroabietylamine Ureas and Thioureas as Tyrosyl-DNA Phosphodiesterase 1 Inhibitors That Enhance the Antitumor Effect of Temozolomide on Glioblastoma Cells.
    Journal of natural products, 2019, 09-27, Volume: 82, Issue:9

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; DNA, Neoplasm; Drug Synergism;

2019
Tim-3 expression in glioma cells is associated with drug resistance.
    Journal of cancer research and therapeutics, 2019, Volume: 15, Issue:4

    Topics: Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cell Proliferation; Drug Resistance,

2019
Tim-3 expression in glioma cells is associated with drug resistance.
    Journal of cancer research and therapeutics, 2019, Volume: 15, Issue:4

    Topics: Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cell Proliferation; Drug Resistance,

2019
Tim-3 expression in glioma cells is associated with drug resistance.
    Journal of cancer research and therapeutics, 2019, Volume: 15, Issue:4

    Topics: Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cell Proliferation; Drug Resistance,

2019
Synergistic combination of chemo‑phototherapy based on temozolomide/ICG‑loaded iron oxide nanoparticles for brain cancer treatment.
    Oncology reports, 2019, Volume: 42, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Cell Survi

2019
Synergistic combination of chemo‑phototherapy based on temozolomide/ICG‑loaded iron oxide nanoparticles for brain cancer treatment.
    Oncology reports, 2019, Volume: 42, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Cell Survi

2019
Synergistic combination of chemo‑phototherapy based on temozolomide/ICG‑loaded iron oxide nanoparticles for brain cancer treatment.
    Oncology reports, 2019, Volume: 42, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Cell Survi

2019
A local combination therapy to inhibit GBM recurrence.
    Journal of controlled release : official journal of the Controlled Release Society, 2019, 09-10, Volume: 309

    Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Drug Carriers; Drug Delivery Systems; Glioblastoma;

2019
A local combination therapy to inhibit GBM recurrence.
    Journal of controlled release : official journal of the Controlled Release Society, 2019, 09-10, Volume: 309

    Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Drug Carriers; Drug Delivery Systems; Glioblastoma;

2019
A local combination therapy to inhibit GBM recurrence.
    Journal of controlled release : official journal of the Controlled Release Society, 2019, 09-10, Volume: 309

    Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Drug Carriers; Drug Delivery Systems; Glioblastoma;

2019
Temozolomide has anti-tumor effects through the phosphorylation of cPLA
    Brain research, 2019, 11-15, Volume: 1723

    Topics: Animals; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Cell Survival; Glioblasto

2019
Temozolomide has anti-tumor effects through the phosphorylation of cPLA
    Brain research, 2019, 11-15, Volume: 1723

    Topics: Animals; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Cell Survival; Glioblasto

2019
Temozolomide has anti-tumor effects through the phosphorylation of cPLA
    Brain research, 2019, 11-15, Volume: 1723

    Topics: Animals; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Cell Survival; Glioblasto

2019
TMZ regulates GBM stemness via MMP14-DLL4-Notch3 pathway.
    International journal of cancer, 2020, 04-15, Volume: 146, Issue:8

    Topics: Animals; Biomarkers, Tumor; Brain Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; Early Grow

2020
TMZ regulates GBM stemness via MMP14-DLL4-Notch3 pathway.
    International journal of cancer, 2020, 04-15, Volume: 146, Issue:8

    Topics: Animals; Biomarkers, Tumor; Brain Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; Early Grow

2020
TMZ regulates GBM stemness via MMP14-DLL4-Notch3 pathway.
    International journal of cancer, 2020, 04-15, Volume: 146, Issue:8

    Topics: Animals; Biomarkers, Tumor; Brain Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; Early Grow

2020
Modulating lncRNA SNHG15/CDK6/miR-627 circuit by palbociclib, overcomes temozolomide resistance and reduces M2-polarization of glioma associated microglia in glioblastoma multiforme.
    Journal of experimental & clinical cancer research : CR, 2019, Aug-28, Volume: 38, Issue:1

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Cell Line, Tumor; Cyclin-D

2019
Modulating lncRNA SNHG15/CDK6/miR-627 circuit by palbociclib, overcomes temozolomide resistance and reduces M2-polarization of glioma associated microglia in glioblastoma multiforme.
    Journal of experimental & clinical cancer research : CR, 2019, Aug-28, Volume: 38, Issue:1

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Cell Line, Tumor; Cyclin-D

2019
Modulating lncRNA SNHG15/CDK6/miR-627 circuit by palbociclib, overcomes temozolomide resistance and reduces M2-polarization of glioma associated microglia in glioblastoma multiforme.
    Journal of experimental & clinical cancer research : CR, 2019, Aug-28, Volume: 38, Issue:1

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Cell Line, Tumor; Cyclin-D

2019
Arterial spin labeling perfusion-weighted imaging aids in prediction of molecular biomarkers and survival in glioblastomas.
    European radiology, 2020, Volume: 30, Issue:2

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Biomarkers, Tumor; Brain Neoplasms; Cerebrovascular

2020
Arterial spin labeling perfusion-weighted imaging aids in prediction of molecular biomarkers and survival in glioblastomas.
    European radiology, 2020, Volume: 30, Issue:2

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Biomarkers, Tumor; Brain Neoplasms; Cerebrovascular

2020
Arterial spin labeling perfusion-weighted imaging aids in prediction of molecular biomarkers and survival in glioblastomas.
    European radiology, 2020, Volume: 30, Issue:2

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Biomarkers, Tumor; Brain Neoplasms; Cerebrovascular

2020
LINC01198 promotes proliferation and temozolomide resistance in a NEDD4-1-dependent manner, repressing PTEN expression in glioma.
    Aging, 2019, 08-30, Volume: 11, Issue:16

    Topics: Brain Neoplasms; Cell Proliferation; Drug Resistance, Neoplasm; Female; Gene Expression Regulation,

2019
LINC01198 promotes proliferation and temozolomide resistance in a NEDD4-1-dependent manner, repressing PTEN expression in glioma.
    Aging, 2019, 08-30, Volume: 11, Issue:16

    Topics: Brain Neoplasms; Cell Proliferation; Drug Resistance, Neoplasm; Female; Gene Expression Regulation,

2019
LINC01198 promotes proliferation and temozolomide resistance in a NEDD4-1-dependent manner, repressing PTEN expression in glioma.
    Aging, 2019, 08-30, Volume: 11, Issue:16

    Topics: Brain Neoplasms; Cell Proliferation; Drug Resistance, Neoplasm; Female; Gene Expression Regulation,

2019
Cerebral blood volume and apparent diffusion coefficient - Valuable predictors of non-response to bevacizumab treatment in patients with recurrent glioblastoma.
    Journal of the neurological sciences, 2019, Oct-15, Volume: 405

    Topics: Adult; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Immunological; Bevacizumab; Brain N

2019
Cerebral blood volume and apparent diffusion coefficient - Valuable predictors of non-response to bevacizumab treatment in patients with recurrent glioblastoma.
    Journal of the neurological sciences, 2019, Oct-15, Volume: 405

    Topics: Adult; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Immunological; Bevacizumab; Brain N

2019
Cerebral blood volume and apparent diffusion coefficient - Valuable predictors of non-response to bevacizumab treatment in patients with recurrent glioblastoma.
    Journal of the neurological sciences, 2019, Oct-15, Volume: 405

    Topics: Adult; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Immunological; Bevacizumab; Brain N

2019
Validation and optimization of a web-based nomogram for predicting survival of patients with newly diagnosed glioblastoma.
    Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 2020, Volume: 196, Issue:1

    Topics: Aged; Algorithms; Brain Neoplasms; Chemoradiotherapy, Adjuvant; Combined Modality Therapy; Female; G

2020
Validation and optimization of a web-based nomogram for predicting survival of patients with newly diagnosed glioblastoma.
    Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 2020, Volume: 196, Issue:1

    Topics: Aged; Algorithms; Brain Neoplasms; Chemoradiotherapy, Adjuvant; Combined Modality Therapy; Female; G

2020
Validation and optimization of a web-based nomogram for predicting survival of patients with newly diagnosed glioblastoma.
    Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 2020, Volume: 196, Issue:1

    Topics: Aged; Algorithms; Brain Neoplasms; Chemoradiotherapy, Adjuvant; Combined Modality Therapy; Female; G

2020
MicroRNA-1 suppresses glioblastoma in preclinical models by targeting fibronectin.
    Cancer letters, 2019, Nov-28, Volume: 465

    Topics: 3' Untranslated Regions; Animals; Brain Neoplasms; Cell Line, Tumor; Cell Movement; Cell Proliferati

2019
MicroRNA-1 suppresses glioblastoma in preclinical models by targeting fibronectin.
    Cancer letters, 2019, Nov-28, Volume: 465

    Topics: 3' Untranslated Regions; Animals; Brain Neoplasms; Cell Line, Tumor; Cell Movement; Cell Proliferati

2019
MicroRNA-1 suppresses glioblastoma in preclinical models by targeting fibronectin.
    Cancer letters, 2019, Nov-28, Volume: 465

    Topics: 3' Untranslated Regions; Animals; Brain Neoplasms; Cell Line, Tumor; Cell Movement; Cell Proliferati

2019
The Evaluation of Glioblastoma Cell Dissociation and Its Influence on Its Behavior.
    International journal of molecular sciences, 2019, Sep-18, Volume: 20, Issue:18

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Cell Movement; Cell Proliferat

2019
The Evaluation of Glioblastoma Cell Dissociation and Its Influence on Its Behavior.
    International journal of molecular sciences, 2019, Sep-18, Volume: 20, Issue:18

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Cell Movement; Cell Proliferat

2019
The Evaluation of Glioblastoma Cell Dissociation and Its Influence on Its Behavior.
    International journal of molecular sciences, 2019, Sep-18, Volume: 20, Issue:18

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Cell Movement; Cell Proliferat

2019
Mechanisms and Antitumor Activity of a Binary EGFR/DNA-Targeting Strategy Overcomes Resistance of Glioblastoma Stem Cells to Temozolomide.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2019, 12-15, Volume: 25, Issue:24

    Topics: Animals; Antineoplastic Agents, Alkylating; Blood-Brain Barrier; Brain Neoplasms; Cell Line, Tumor;

2019
Mechanisms and Antitumor Activity of a Binary EGFR/DNA-Targeting Strategy Overcomes Resistance of Glioblastoma Stem Cells to Temozolomide.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2019, 12-15, Volume: 25, Issue:24

    Topics: Animals; Antineoplastic Agents, Alkylating; Blood-Brain Barrier; Brain Neoplasms; Cell Line, Tumor;

2019
Mechanisms and Antitumor Activity of a Binary EGFR/DNA-Targeting Strategy Overcomes Resistance of Glioblastoma Stem Cells to Temozolomide.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2019, 12-15, Volume: 25, Issue:24

    Topics: Animals; Antineoplastic Agents, Alkylating; Blood-Brain Barrier; Brain Neoplasms; Cell Line, Tumor;

2019
DHFR/TYMS are positive regulators of glioma cell growth and modulate chemo-sensitivity to temozolomide.
    European journal of pharmacology, 2019, Nov-15, Volume: 863

    Topics: AMP-Activated Protein Kinases; Animals; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Cell

2019
DHFR/TYMS are positive regulators of glioma cell growth and modulate chemo-sensitivity to temozolomide.
    European journal of pharmacology, 2019, Nov-15, Volume: 863

    Topics: AMP-Activated Protein Kinases; Animals; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Cell

2019
DHFR/TYMS are positive regulators of glioma cell growth and modulate chemo-sensitivity to temozolomide.
    European journal of pharmacology, 2019, Nov-15, Volume: 863

    Topics: AMP-Activated Protein Kinases; Animals; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Cell

2019
Irradiation or temozolomide chemotherapy enhances anti-CD47 treatment of glioblastoma.
    Innate immunity, 2020, Volume: 26, Issue:2

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; CD47 Antigen; Cell Line, Tumor; Combine

2020
Irradiation or temozolomide chemotherapy enhances anti-CD47 treatment of glioblastoma.
    Innate immunity, 2020, Volume: 26, Issue:2

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; CD47 Antigen; Cell Line, Tumor; Combine

2020
Irradiation or temozolomide chemotherapy enhances anti-CD47 treatment of glioblastoma.
    Innate immunity, 2020, Volume: 26, Issue:2

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; CD47 Antigen; Cell Line, Tumor; Combine

2020
Bevacizumab Reduces Permeability and Concurrent Temozolomide Delivery in a Subset of Patients with Recurrent Glioblastoma.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2020, 01-01, Volume: 26, Issue:1

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Brain Neoplasms; Capillary

2020
Bevacizumab Reduces Permeability and Concurrent Temozolomide Delivery in a Subset of Patients with Recurrent Glioblastoma.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2020, 01-01, Volume: 26, Issue:1

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Brain Neoplasms; Capillary

2020
Bevacizumab Reduces Permeability and Concurrent Temozolomide Delivery in a Subset of Patients with Recurrent Glioblastoma.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2020, 01-01, Volume: 26, Issue:1

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Brain Neoplasms; Capillary

2020
Targeting Aurora kinase B attenuates chemoresistance in glioblastoma via a synergistic manner with temozolomide.
    Pathology, research and practice, 2019, Volume: 215, Issue:11

    Topics: Animals; Antineoplastic Agents; Aurora Kinase B; Brain Neoplasms; Drug Resistance, Neoplasm; Drug Sy

2019
Targeting Aurora kinase B attenuates chemoresistance in glioblastoma via a synergistic manner with temozolomide.
    Pathology, research and practice, 2019, Volume: 215, Issue:11

    Topics: Animals; Antineoplastic Agents; Aurora Kinase B; Brain Neoplasms; Drug Resistance, Neoplasm; Drug Sy

2019
Targeting Aurora kinase B attenuates chemoresistance in glioblastoma via a synergistic manner with temozolomide.
    Pathology, research and practice, 2019, Volume: 215, Issue:11

    Topics: Animals; Antineoplastic Agents; Aurora Kinase B; Brain Neoplasms; Drug Resistance, Neoplasm; Drug Sy

2019
Prognostic impact of glioblastoma stem cell markers OLIG2 and CCND2.
    Cancer medicine, 2020, Volume: 9, Issue:3

    Topics: Adult; Aged; Brain; Brain Neoplasms; Cell Nucleus; Chemoradiotherapy, Adjuvant; Cyclin D2; Female; G

2020
Prognostic impact of glioblastoma stem cell markers OLIG2 and CCND2.
    Cancer medicine, 2020, Volume: 9, Issue:3

    Topics: Adult; Aged; Brain; Brain Neoplasms; Cell Nucleus; Chemoradiotherapy, Adjuvant; Cyclin D2; Female; G

2020
Prognostic impact of glioblastoma stem cell markers OLIG2 and CCND2.
    Cancer medicine, 2020, Volume: 9, Issue:3

    Topics: Adult; Aged; Brain; Brain Neoplasms; Cell Nucleus; Chemoradiotherapy, Adjuvant; Cyclin D2; Female; G

2020
Acquisition of temozolomide resistance by the rat C6 glioma cell line increases cell migration and side population phenotype.
    Oncology reports, 2019, Volume: 42, Issue:6

    Topics: Animals; Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cell Movement; Cell Prolifer

2019
Acquisition of temozolomide resistance by the rat C6 glioma cell line increases cell migration and side population phenotype.
    Oncology reports, 2019, Volume: 42, Issue:6

    Topics: Animals; Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cell Movement; Cell Prolifer

2019
Acquisition of temozolomide resistance by the rat C6 glioma cell line increases cell migration and side population phenotype.
    Oncology reports, 2019, Volume: 42, Issue:6

    Topics: Animals; Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cell Movement; Cell Prolifer

2019
The polymorphisms (rs3213801 and rs5744533) of DNA polymerase kappa gene are not related with glioma risk and prognosis: A case-control study.
    Cancer medicine, 2019, Volume: 8, Issue:17

    Topics: Adult; Age Factors; Antineoplastic Agents, Alkylating; Asian People; Brain; Brain Neoplasms; Case-Co

2019
The polymorphisms (rs3213801 and rs5744533) of DNA polymerase kappa gene are not related with glioma risk and prognosis: A case-control study.
    Cancer medicine, 2019, Volume: 8, Issue:17

    Topics: Adult; Age Factors; Antineoplastic Agents, Alkylating; Asian People; Brain; Brain Neoplasms; Case-Co

2019
The polymorphisms (rs3213801 and rs5744533) of DNA polymerase kappa gene are not related with glioma risk and prognosis: A case-control study.
    Cancer medicine, 2019, Volume: 8, Issue:17

    Topics: Adult; Age Factors; Antineoplastic Agents, Alkylating; Asian People; Brain; Brain Neoplasms; Case-Co

2019
Knockdown of circular RNA CEP128 suppresses proliferation and improves cytotoxic efficacy of temozolomide in glioma cells by regulating miR-145-5p.
    Neuroreport, 2019, 12-18, Volume: 30, Issue:18

    Topics: Antineoplastic Agents; Astrocytes; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Gene Expre

2019
Knockdown of circular RNA CEP128 suppresses proliferation and improves cytotoxic efficacy of temozolomide in glioma cells by regulating miR-145-5p.
    Neuroreport, 2019, 12-18, Volume: 30, Issue:18

    Topics: Antineoplastic Agents; Astrocytes; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Gene Expre

2019
Knockdown of circular RNA CEP128 suppresses proliferation and improves cytotoxic efficacy of temozolomide in glioma cells by regulating miR-145-5p.
    Neuroreport, 2019, 12-18, Volume: 30, Issue:18

    Topics: Antineoplastic Agents; Astrocytes; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Gene Expre

2019
BMP signaling mediates glioma stem cell quiescence and confers treatment resistance in glioblastoma.
    Scientific reports, 2019, 10-10, Volume: 9, Issue:1

    Topics: Animals; Antineoplastic Agents; Bone Morphogenetic Protein 4; Bone Morphogenetic Proteins; Brain Neo

2019
BMP signaling mediates glioma stem cell quiescence and confers treatment resistance in glioblastoma.
    Scientific reports, 2019, 10-10, Volume: 9, Issue:1

    Topics: Animals; Antineoplastic Agents; Bone Morphogenetic Protein 4; Bone Morphogenetic Proteins; Brain Neo

2019
BMP signaling mediates glioma stem cell quiescence and confers treatment resistance in glioblastoma.
    Scientific reports, 2019, 10-10, Volume: 9, Issue:1

    Topics: Animals; Antineoplastic Agents; Bone Morphogenetic Protein 4; Bone Morphogenetic Proteins; Brain Neo

2019
Personalized oncology with artificial intelligence: The case of temozolomide.
    Artificial intelligence in medicine, 2019, Volume: 99

    Topics: Algorithms; Artificial Intelligence; Bayes Theorem; Brain Neoplasms; Computer Simulation; Dose-Respo

2019
Personalized oncology with artificial intelligence: The case of temozolomide.
    Artificial intelligence in medicine, 2019, Volume: 99

    Topics: Algorithms; Artificial Intelligence; Bayes Theorem; Brain Neoplasms; Computer Simulation; Dose-Respo

2019
Personalized oncology with artificial intelligence: The case of temozolomide.
    Artificial intelligence in medicine, 2019, Volume: 99

    Topics: Algorithms; Artificial Intelligence; Bayes Theorem; Brain Neoplasms; Computer Simulation; Dose-Respo

2019
Nuclear factor I A promotes temozolomide resistance in glioblastoma via activation of nuclear factor κB pathway.
    Life sciences, 2019, Nov-01, Volume: 236

    Topics: Animals; Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cell Proliferation; Drug Res

2019
Nuclear factor I A promotes temozolomide resistance in glioblastoma via activation of nuclear factor κB pathway.
    Life sciences, 2019, Nov-01, Volume: 236

    Topics: Animals; Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cell Proliferation; Drug Res

2019
Nuclear factor I A promotes temozolomide resistance in glioblastoma via activation of nuclear factor κB pathway.
    Life sciences, 2019, Nov-01, Volume: 236

    Topics: Animals; Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cell Proliferation; Drug Res

2019
Blood-Brain Barrier- and Blood-Brain Tumor Barrier-Penetrating Peptide-Derived Targeted Therapeutics for Glioma and Malignant Tumor Brain Metastases.
    ACS applied materials & interfaces, 2019, Nov-13, Volume: 11, Issue:45

    Topics: Animals; Antineoplastic Agents; Blood-Brain Barrier; Brain Neoplasms; Cell Line, Tumor; Drug Deliver

2019
Blood-Brain Barrier- and Blood-Brain Tumor Barrier-Penetrating Peptide-Derived Targeted Therapeutics for Glioma and Malignant Tumor Brain Metastases.
    ACS applied materials & interfaces, 2019, Nov-13, Volume: 11, Issue:45

    Topics: Animals; Antineoplastic Agents; Blood-Brain Barrier; Brain Neoplasms; Cell Line, Tumor; Drug Deliver

2019
Blood-Brain Barrier- and Blood-Brain Tumor Barrier-Penetrating Peptide-Derived Targeted Therapeutics for Glioma and Malignant Tumor Brain Metastases.
    ACS applied materials & interfaces, 2019, Nov-13, Volume: 11, Issue:45

    Topics: Animals; Antineoplastic Agents; Blood-Brain Barrier; Brain Neoplasms; Cell Line, Tumor; Drug Deliver

2019
ABCB1 single-nucleotide variants and survival in patients with glioblastoma treated with radiotherapy concomitant with temozolomide.
    The pharmacogenomics journal, 2020, Volume: 20, Issue:2

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; ATP Binding Cassette Transporter, Subfamily B; Brain

2020
ABCB1 single-nucleotide variants and survival in patients with glioblastoma treated with radiotherapy concomitant with temozolomide.
    The pharmacogenomics journal, 2020, Volume: 20, Issue:2

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; ATP Binding Cassette Transporter, Subfamily B; Brain

2020
ABCB1 single-nucleotide variants and survival in patients with glioblastoma treated with radiotherapy concomitant with temozolomide.
    The pharmacogenomics journal, 2020, Volume: 20, Issue:2

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; ATP Binding Cassette Transporter, Subfamily B; Brain

2020
A new chance for EGFR inhibition in glioblastoma?
    Neuro-oncology, 2019, 12-17, Volume: 21, Issue:12

    Topics: Brain Neoplasms; ErbB Receptors; Glioblastoma; Humans; Temozolomide

2019
A new chance for EGFR inhibition in glioblastoma?
    Neuro-oncology, 2019, 12-17, Volume: 21, Issue:12

    Topics: Brain Neoplasms; ErbB Receptors; Glioblastoma; Humans; Temozolomide

2019
A new chance for EGFR inhibition in glioblastoma?
    Neuro-oncology, 2019, 12-17, Volume: 21, Issue:12

    Topics: Brain Neoplasms; ErbB Receptors; Glioblastoma; Humans; Temozolomide

2019
Treatment strategies for glioblastoma in older patients: age is just a number.
    Journal of neuro-oncology, 2019, Volume: 145, Issue:2

    Topics: Age Factors; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cohort Stu

2019
Treatment strategies for glioblastoma in older patients: age is just a number.
    Journal of neuro-oncology, 2019, Volume: 145, Issue:2

    Topics: Age Factors; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cohort Stu

2019
Treatment strategies for glioblastoma in older patients: age is just a number.
    Journal of neuro-oncology, 2019, Volume: 145, Issue:2

    Topics: Age Factors; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cohort Stu

2019
Enhanced Copper-Temozolomide Interactions by Protein for Chemotherapy against Glioblastoma Multiforme.
    ACS applied materials & interfaces, 2019, Nov-13, Volume: 11, Issue:45

    Topics: Antineoplastic Agents; Apoferritins; Brain Neoplasms; Cell Line, Tumor; Copper; Glioblastoma; Humans

2019
Enhanced Copper-Temozolomide Interactions by Protein for Chemotherapy against Glioblastoma Multiforme.
    ACS applied materials & interfaces, 2019, Nov-13, Volume: 11, Issue:45

    Topics: Antineoplastic Agents; Apoferritins; Brain Neoplasms; Cell Line, Tumor; Copper; Glioblastoma; Humans

2019
Enhanced Copper-Temozolomide Interactions by Protein for Chemotherapy against Glioblastoma Multiforme.
    ACS applied materials & interfaces, 2019, Nov-13, Volume: 11, Issue:45

    Topics: Antineoplastic Agents; Apoferritins; Brain Neoplasms; Cell Line, Tumor; Copper; Glioblastoma; Humans

2019
Intracellular Redox-Balance Involvement in Temozolomide Resistance-Related Molecular Mechanisms in Glioblastoma.
    Cells, 2019, 10-24, Volume: 8, Issue:11

    Topics: Apoptosis; Autophagy; Brain Neoplasms; Cell Line, Tumor; Chaperone-Mediated Autophagy; Cytoplasm; Dr

2019
Intracellular Redox-Balance Involvement in Temozolomide Resistance-Related Molecular Mechanisms in Glioblastoma.
    Cells, 2019, 10-24, Volume: 8, Issue:11

    Topics: Apoptosis; Autophagy; Brain Neoplasms; Cell Line, Tumor; Chaperone-Mediated Autophagy; Cytoplasm; Dr

2019
Intracellular Redox-Balance Involvement in Temozolomide Resistance-Related Molecular Mechanisms in Glioblastoma.
    Cells, 2019, 10-24, Volume: 8, Issue:11

    Topics: Apoptosis; Autophagy; Brain Neoplasms; Cell Line, Tumor; Chaperone-Mediated Autophagy; Cytoplasm; Dr

2019
Lovastatin Enhances Cytotoxicity of Temozolomide via Impairing Autophagic Flux in Glioblastoma Cells.
    BioMed research international, 2019, Volume: 2019

    Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Autophagy; Brain N

2019
Lovastatin Enhances Cytotoxicity of Temozolomide via Impairing Autophagic Flux in Glioblastoma Cells.
    BioMed research international, 2019, Volume: 2019

    Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Autophagy; Brain N

2019
Lovastatin Enhances Cytotoxicity of Temozolomide via Impairing Autophagic Flux in Glioblastoma Cells.
    BioMed research international, 2019, Volume: 2019

    Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Autophagy; Brain N

2019
Carnosine increases efficiency of temozolomide and irradiation treatment of isocitrate dehydrogenase-wildtype glioblastoma cells in culture.
    Future oncology (London, England), 2019, Volume: 15, Issue:32

    Topics: Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Carnosine; Cell Survival; Female; Glioblas

2019
Carnosine increases efficiency of temozolomide and irradiation treatment of isocitrate dehydrogenase-wildtype glioblastoma cells in culture.
    Future oncology (London, England), 2019, Volume: 15, Issue:32

    Topics: Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Carnosine; Cell Survival; Female; Glioblas

2019
Carnosine increases efficiency of temozolomide and irradiation treatment of isocitrate dehydrogenase-wildtype glioblastoma cells in culture.
    Future oncology (London, England), 2019, Volume: 15, Issue:32

    Topics: Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Carnosine; Cell Survival; Female; Glioblas

2019
Eukaryotic initiation factor 5B (eIF5B) regulates temozolomide-mediated apoptosis in brain tumour stem cells (BTSCs).
    Biochemistry and cell biology = Biochimie et biologie cellulaire, 2020, Volume: 98, Issue:6

    Topics: Apoptosis; Brain Neoplasms; Cell Line, Tumor; Eukaryotic Initiation Factors; Humans; Neoplasm Protei

2020
Eukaryotic initiation factor 5B (eIF5B) regulates temozolomide-mediated apoptosis in brain tumour stem cells (BTSCs).
    Biochemistry and cell biology = Biochimie et biologie cellulaire, 2020, Volume: 98, Issue:6

    Topics: Apoptosis; Brain Neoplasms; Cell Line, Tumor; Eukaryotic Initiation Factors; Humans; Neoplasm Protei

2020
Eukaryotic initiation factor 5B (eIF5B) regulates temozolomide-mediated apoptosis in brain tumour stem cells (BTSCs).
    Biochemistry and cell biology = Biochimie et biologie cellulaire, 2020, Volume: 98, Issue:6

    Topics: Apoptosis; Brain Neoplasms; Cell Line, Tumor; Eukaryotic Initiation Factors; Humans; Neoplasm Protei

2020
Integrated proteomic and metabolomic profiling the global response of rat glioma model by temozolomide treatment.
    Journal of proteomics, 2020, 01-16, Volume: 211

    Topics: Animals; Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cell Line, Tumor; G2 Phase C

2020
Integrated proteomic and metabolomic profiling the global response of rat glioma model by temozolomide treatment.
    Journal of proteomics, 2020, 01-16, Volume: 211

    Topics: Animals; Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cell Line, Tumor; G2 Phase C

2020
Integrated proteomic and metabolomic profiling the global response of rat glioma model by temozolomide treatment.
    Journal of proteomics, 2020, 01-16, Volume: 211

    Topics: Animals; Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cell Line, Tumor; G2 Phase C

2020
A man with weak limbs.
    BMJ (Clinical research ed.), 2019, Nov-07, Volume: 367

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Craniotomy; Glioblastoma; Humans; Magnetic Reson

2019
A man with weak limbs.
    BMJ (Clinical research ed.), 2019, Nov-07, Volume: 367

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Craniotomy; Glioblastoma; Humans; Magnetic Reson

2019
A man with weak limbs.
    BMJ (Clinical research ed.), 2019, Nov-07, Volume: 367

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Craniotomy; Glioblastoma; Humans; Magnetic Reson

2019
Weak MGMT gene promoter methylation confers a clinically significant survival benefit in patients with newly diagnosed glioblastoma: a retrospective cohort study.
    Journal of neuro-oncology, 2020, Volume: 146, Issue:1

    Topics: Aged; Antineoplastic Agents, Alkylating; Biomarkers, Tumor; Brain Neoplasms; Chemoradiotherapy; Comb

2020
Weak MGMT gene promoter methylation confers a clinically significant survival benefit in patients with newly diagnosed glioblastoma: a retrospective cohort study.
    Journal of neuro-oncology, 2020, Volume: 146, Issue:1

    Topics: Aged; Antineoplastic Agents, Alkylating; Biomarkers, Tumor; Brain Neoplasms; Chemoradiotherapy; Comb

2020
Weak MGMT gene promoter methylation confers a clinically significant survival benefit in patients with newly diagnosed glioblastoma: a retrospective cohort study.
    Journal of neuro-oncology, 2020, Volume: 146, Issue:1

    Topics: Aged; Antineoplastic Agents, Alkylating; Biomarkers, Tumor; Brain Neoplasms; Chemoradiotherapy; Comb

2020
Extensive brainstem infiltration, not mass effect, is a common feature of end-stage cerebral glioblastomas.
    Neuro-oncology, 2020, 04-15, Volume: 22, Issue:4

    Topics: Aged; Brain Neoplasms; Brain Stem; Glioblastoma; Humans; Supratentorial Neoplasms; Temozolomide

2020
Extensive brainstem infiltration, not mass effect, is a common feature of end-stage cerebral glioblastomas.
    Neuro-oncology, 2020, 04-15, Volume: 22, Issue:4

    Topics: Aged; Brain Neoplasms; Brain Stem; Glioblastoma; Humans; Supratentorial Neoplasms; Temozolomide

2020
Extensive brainstem infiltration, not mass effect, is a common feature of end-stage cerebral glioblastomas.
    Neuro-oncology, 2020, 04-15, Volume: 22, Issue:4

    Topics: Aged; Brain Neoplasms; Brain Stem; Glioblastoma; Humans; Supratentorial Neoplasms; Temozolomide

2020
LINC00174 down-regulation decreases chemoresistance to temozolomide in human glioma cells by regulating miR-138-5p/SOX9 axis.
    Human cell, 2020, Volume: 33, Issue:1

    Topics: Brain Neoplasms; Drug Resistance, Neoplasm; Glioma; Humans; MicroRNAs; SOX9 Transcription Factor; Te

2020
LINC00174 down-regulation decreases chemoresistance to temozolomide in human glioma cells by regulating miR-138-5p/SOX9 axis.
    Human cell, 2020, Volume: 33, Issue:1

    Topics: Brain Neoplasms; Drug Resistance, Neoplasm; Glioma; Humans; MicroRNAs; SOX9 Transcription Factor; Te

2020
LINC00174 down-regulation decreases chemoresistance to temozolomide in human glioma cells by regulating miR-138-5p/SOX9 axis.
    Human cell, 2020, Volume: 33, Issue:1

    Topics: Brain Neoplasms; Drug Resistance, Neoplasm; Glioma; Humans; MicroRNAs; SOX9 Transcription Factor; Te

2020
ANGPTL4 Induces TMZ Resistance of Glioblastoma by Promoting Cancer Stemness Enrichment via the EGFR/AKT/4E-BP1 Cascade.
    International journal of molecular sciences, 2019, Nov-11, Volume: 20, Issue:22

    Topics: Adaptor Proteins, Signal Transducing; Angiopoietin-Like Protein 4; Antineoplastic Agents, Alkylating

2019
ANGPTL4 Induces TMZ Resistance of Glioblastoma by Promoting Cancer Stemness Enrichment via the EGFR/AKT/4E-BP1 Cascade.
    International journal of molecular sciences, 2019, Nov-11, Volume: 20, Issue:22

    Topics: Adaptor Proteins, Signal Transducing; Angiopoietin-Like Protein 4; Antineoplastic Agents, Alkylating

2019
ANGPTL4 Induces TMZ Resistance of Glioblastoma by Promoting Cancer Stemness Enrichment via the EGFR/AKT/4E-BP1 Cascade.
    International journal of molecular sciences, 2019, Nov-11, Volume: 20, Issue:22

    Topics: Adaptor Proteins, Signal Transducing; Angiopoietin-Like Protein 4; Antineoplastic Agents, Alkylating

2019
Survival benefits of hypofractionated radiotherapy combined with temozolomide or temozolomide plus bevacizumab in elderly patients with glioblastoma aged ≥ 75 years.
    Radiation oncology (London, England), 2019, Nov-12, Volume: 14, Issue:1

    Topics: Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Pro

2019
Survival benefits of hypofractionated radiotherapy combined with temozolomide or temozolomide plus bevacizumab in elderly patients with glioblastoma aged ≥ 75 years.
    Radiation oncology (London, England), 2019, Nov-12, Volume: 14, Issue:1

    Topics: Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Pro

2019
Survival benefits of hypofractionated radiotherapy combined with temozolomide or temozolomide plus bevacizumab in elderly patients with glioblastoma aged ≥ 75 years.
    Radiation oncology (London, England), 2019, Nov-12, Volume: 14, Issue:1

    Topics: Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Pro

2019
Efficient delivery of anti-miR-210 using Tachyplesin, a cell penetrating peptide, for glioblastoma treatment.
    International journal of pharmaceutics, 2019, Dec-15, Volume: 572

    Topics: Antagomirs; Antimicrobial Cationic Peptides; Antineoplastic Agents; Antineoplastic Agents, Alkylatin

2019
Efficient delivery of anti-miR-210 using Tachyplesin, a cell penetrating peptide, for glioblastoma treatment.
    International journal of pharmaceutics, 2019, Dec-15, Volume: 572

    Topics: Antagomirs; Antimicrobial Cationic Peptides; Antineoplastic Agents; Antineoplastic Agents, Alkylatin

2019
Efficient delivery of anti-miR-210 using Tachyplesin, a cell penetrating peptide, for glioblastoma treatment.
    International journal of pharmaceutics, 2019, Dec-15, Volume: 572

    Topics: Antagomirs; Antimicrobial Cationic Peptides; Antineoplastic Agents; Antineoplastic Agents, Alkylatin

2019
Inhibition of phosphatidylinositol 3-kinase by PX-866 suppresses temozolomide-induced autophagy and promotes apoptosis in glioblastoma cells.
    Molecular medicine (Cambridge, Mass.), 2019, 11-14, Volume: 25, Issue:1

    Topics: Apoptosis; Autophagy; Brain Neoplasms; Cell Line, Tumor; Glioblastoma; Gonanes; Humans; Phosphatidyl

2019
Inhibition of phosphatidylinositol 3-kinase by PX-866 suppresses temozolomide-induced autophagy and promotes apoptosis in glioblastoma cells.
    Molecular medicine (Cambridge, Mass.), 2019, 11-14, Volume: 25, Issue:1

    Topics: Apoptosis; Autophagy; Brain Neoplasms; Cell Line, Tumor; Glioblastoma; Gonanes; Humans; Phosphatidyl

2019
Inhibition of phosphatidylinositol 3-kinase by PX-866 suppresses temozolomide-induced autophagy and promotes apoptosis in glioblastoma cells.
    Molecular medicine (Cambridge, Mass.), 2019, 11-14, Volume: 25, Issue:1

    Topics: Apoptosis; Autophagy; Brain Neoplasms; Cell Line, Tumor; Glioblastoma; Gonanes; Humans; Phosphatidyl

2019
Craniotomy for recurrent glioblastoma: Is it justified? A comparative cohort study with outcomes over 10 years.
    Clinical neurology and neurosurgery, 2020, Volume: 188

    Topics: Adolescent; Adult; Age Factors; Aged; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Immu

2020
Craniotomy for recurrent glioblastoma: Is it justified? A comparative cohort study with outcomes over 10 years.
    Clinical neurology and neurosurgery, 2020, Volume: 188

    Topics: Adolescent; Adult; Age Factors; Aged; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Immu

2020
Craniotomy for recurrent glioblastoma: Is it justified? A comparative cohort study with outcomes over 10 years.
    Clinical neurology and neurosurgery, 2020, Volume: 188

    Topics: Adolescent; Adult; Age Factors; Aged; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Immu

2020
Molecular Evolution of
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2020, 01-01, Volume: 38, Issue:1

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Case-Control Studies; C

2020
Molecular Evolution of
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2020, 01-01, Volume: 38, Issue:1

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Case-Control Studies; C

2020
Molecular Evolution of
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2020, 01-01, Volume: 38, Issue:1

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Case-Control Studies; C

2020
LQB‑118 compound inhibits migration and induces cell death in glioblastoma cells.
    Oncology reports, 2020, Volume: 43, Issue:1

    Topics: Brain Neoplasms; Cell Culture Techniques; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cell

2020
LQB‑118 compound inhibits migration and induces cell death in glioblastoma cells.
    Oncology reports, 2020, Volume: 43, Issue:1

    Topics: Brain Neoplasms; Cell Culture Techniques; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cell

2020
LQB‑118 compound inhibits migration and induces cell death in glioblastoma cells.
    Oncology reports, 2020, Volume: 43, Issue:1

    Topics: Brain Neoplasms; Cell Culture Techniques; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cell

2020
Experience of Low Dose Perampanel to Add-on in Glioma Patients with Levetiracetam-uncontrollable Epilepsy.
    Neurologia medico-chirurgica, 2020, Jan-15, Volume: 60, Issue:1

    Topics: Adult; Aged; Anticonvulsants; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Brain Neo

2020
Experience of Low Dose Perampanel to Add-on in Glioma Patients with Levetiracetam-uncontrollable Epilepsy.
    Neurologia medico-chirurgica, 2020, Jan-15, Volume: 60, Issue:1

    Topics: Adult; Aged; Anticonvulsants; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Brain Neo

2020
Experience of Low Dose Perampanel to Add-on in Glioma Patients with Levetiracetam-uncontrollable Epilepsy.
    Neurologia medico-chirurgica, 2020, Jan-15, Volume: 60, Issue:1

    Topics: Adult; Aged; Anticonvulsants; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Brain Neo

2020
[RAD51 promotes proliferation and migration of glioblastoma cells and decreases sensitivity of cells to temozolomide].
    Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology, 2019, Volume: 35, Issue:9

    Topics: Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cell Movement; Cell Proliferation; Gene Knockdown Tech

2019
[RAD51 promotes proliferation and migration of glioblastoma cells and decreases sensitivity of cells to temozolomide].
    Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology, 2019, Volume: 35, Issue:9

    Topics: Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cell Movement; Cell Proliferation; Gene Knockdown Tech

2019
[RAD51 promotes proliferation and migration of glioblastoma cells and decreases sensitivity of cells to temozolomide].
    Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology, 2019, Volume: 35, Issue:9

    Topics: Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cell Movement; Cell Proliferation; Gene Knockdown Tech

2019
BET and Aurora Kinase A inhibitors synergize against MYCN-positive human glioblastoma cells.
    Cell death & disease, 2019, 11-21, Volume: 10, Issue:12

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Aurora Kinase A; Azepines; Brain Neopla

2019
BET and Aurora Kinase A inhibitors synergize against MYCN-positive human glioblastoma cells.
    Cell death & disease, 2019, 11-21, Volume: 10, Issue:12

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Aurora Kinase A; Azepines; Brain Neopla

2019
BET and Aurora Kinase A inhibitors synergize against MYCN-positive human glioblastoma cells.
    Cell death & disease, 2019, 11-21, Volume: 10, Issue:12

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Aurora Kinase A; Azepines; Brain Neopla

2019
Musashi1 enhances chemotherapy resistance of pediatric glioblastoma cells in vitro.
    Pediatric research, 2020, Volume: 87, Issue:4

    Topics: Adolescent; Age Factors; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Case-Contr

2020
Musashi1 enhances chemotherapy resistance of pediatric glioblastoma cells in vitro.
    Pediatric research, 2020, Volume: 87, Issue:4

    Topics: Adolescent; Age Factors; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Case-Contr

2020
Musashi1 enhances chemotherapy resistance of pediatric glioblastoma cells in vitro.
    Pediatric research, 2020, Volume: 87, Issue:4

    Topics: Adolescent; Age Factors; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Case-Contr

2020
Temozolomide induces activation of Wnt/β-catenin signaling in glioma cells via PI3K/Akt pathway: implications in glioma therapy.
    Cell biology and toxicology, 2020, Volume: 36, Issue:3

    Topics: beta Catenin; Brain Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; Gene Expression Regulati

2020
Temozolomide induces activation of Wnt/β-catenin signaling in glioma cells via PI3K/Akt pathway: implications in glioma therapy.
    Cell biology and toxicology, 2020, Volume: 36, Issue:3

    Topics: beta Catenin; Brain Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; Gene Expression Regulati

2020
Temozolomide induces activation of Wnt/β-catenin signaling in glioma cells via PI3K/Akt pathway: implications in glioma therapy.
    Cell biology and toxicology, 2020, Volume: 36, Issue:3

    Topics: beta Catenin; Brain Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; Gene Expression Regulati

2020
Feasibility study of finalizing the extended adjuvant temozolomide based on methionine positron emission tomography (Met-PET) findings in patients with glioblastoma.
    Scientific reports, 2019, 11-28, Volume: 9, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Carbon Radioisot

2019
Feasibility study of finalizing the extended adjuvant temozolomide based on methionine positron emission tomography (Met-PET) findings in patients with glioblastoma.
    Scientific reports, 2019, 11-28, Volume: 9, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Carbon Radioisot

2019
Feasibility study of finalizing the extended adjuvant temozolomide based on methionine positron emission tomography (Met-PET) findings in patients with glioblastoma.
    Scientific reports, 2019, 11-28, Volume: 9, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Carbon Radioisot

2019
Effect of anti-epileptic drugs on the survival of patients with glioblastoma multiforme: A retrospective, single-center study.
    PloS one, 2019, Volume: 14, Issue:12

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anticonvulsants; Antineoplastic Agents, Alkylating; Brai

2019
Effect of anti-epileptic drugs on the survival of patients with glioblastoma multiforme: A retrospective, single-center study.
    PloS one, 2019, Volume: 14, Issue:12

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anticonvulsants; Antineoplastic Agents, Alkylating; Brai

2019
Effect of anti-epileptic drugs on the survival of patients with glioblastoma multiforme: A retrospective, single-center study.
    PloS one, 2019, Volume: 14, Issue:12

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anticonvulsants; Antineoplastic Agents, Alkylating; Brai

2019
Dissecting the role of novel EZH2 inhibitors in primary glioblastoma cell cultures: effects on proliferation, epithelial-mesenchymal transition, migration, and on the pro-inflammatory phenotype.
    Clinical epigenetics, 2019, 12-02, Volume: 11, Issue:1

    Topics: Brain Neoplasms; Cell Movement; Cell Proliferation; Cell Survival; Cytokines; Dose-Response Relation

2019
Dissecting the role of novel EZH2 inhibitors in primary glioblastoma cell cultures: effects on proliferation, epithelial-mesenchymal transition, migration, and on the pro-inflammatory phenotype.
    Clinical epigenetics, 2019, 12-02, Volume: 11, Issue:1

    Topics: Brain Neoplasms; Cell Movement; Cell Proliferation; Cell Survival; Cytokines; Dose-Response Relation

2019
Dissecting the role of novel EZH2 inhibitors in primary glioblastoma cell cultures: effects on proliferation, epithelial-mesenchymal transition, migration, and on the pro-inflammatory phenotype.
    Clinical epigenetics, 2019, 12-02, Volume: 11, Issue:1

    Topics: Brain Neoplasms; Cell Movement; Cell Proliferation; Cell Survival; Cytokines; Dose-Response Relation

2019
Bortezomib inhibits growth and sensitizes glioma to temozolomide (TMZ) via down-regulating the FOXM1-Survivin axis.
    Cancer communications (London, England), 2019, 12-03, Volume: 39, Issue:1

    Topics: Adolescent; Adult; Aged; Animals; Antineoplastic Agents; Apoptosis; Bortezomib; Brain Neoplasms; Cel

2019
Bortezomib inhibits growth and sensitizes glioma to temozolomide (TMZ) via down-regulating the FOXM1-Survivin axis.
    Cancer communications (London, England), 2019, 12-03, Volume: 39, Issue:1

    Topics: Adolescent; Adult; Aged; Animals; Antineoplastic Agents; Apoptosis; Bortezomib; Brain Neoplasms; Cel

2019
Bortezomib inhibits growth and sensitizes glioma to temozolomide (TMZ) via down-regulating the FOXM1-Survivin axis.
    Cancer communications (London, England), 2019, 12-03, Volume: 39, Issue:1

    Topics: Adolescent; Adult; Aged; Animals; Antineoplastic Agents; Apoptosis; Bortezomib; Brain Neoplasms; Cel

2019
Whole brain apparent diffusion coefficient measurements correlate with survival in glioblastoma patients.
    Journal of neuro-oncology, 2020, Volume: 146, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Combined Modality Therapy; Di

2020
Whole brain apparent diffusion coefficient measurements correlate with survival in glioblastoma patients.
    Journal of neuro-oncology, 2020, Volume: 146, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Combined Modality Therapy; Di

2020
Whole brain apparent diffusion coefficient measurements correlate with survival in glioblastoma patients.
    Journal of neuro-oncology, 2020, Volume: 146, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Combined Modality Therapy; Di

2020
Temozolomide-resistant Glioblastoma Depends on HDAC6 Activity Through Regulation of DNA Mismatch Repair.
    Anticancer research, 2019, Volume: 39, Issue:12

    Topics: Antineoplastic Agents, Alkylating; Benzene Derivatives; Brain Neoplasms; Cell Line, Tumor; Cell Surv

2019
Temozolomide-resistant Glioblastoma Depends on HDAC6 Activity Through Regulation of DNA Mismatch Repair.
    Anticancer research, 2019, Volume: 39, Issue:12

    Topics: Antineoplastic Agents, Alkylating; Benzene Derivatives; Brain Neoplasms; Cell Line, Tumor; Cell Surv

2019
Temozolomide-resistant Glioblastoma Depends on HDAC6 Activity Through Regulation of DNA Mismatch Repair.
    Anticancer research, 2019, Volume: 39, Issue:12

    Topics: Antineoplastic Agents, Alkylating; Benzene Derivatives; Brain Neoplasms; Cell Line, Tumor; Cell Surv

2019
Anticancer Non-narcotic Opium Alkaloid Papaverine Suppresses Human Glioblastoma Cell Growth.
    Anticancer research, 2019, Volume: 39, Issue:12

    Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Cel

2019
Anticancer Non-narcotic Opium Alkaloid Papaverine Suppresses Human Glioblastoma Cell Growth.
    Anticancer research, 2019, Volume: 39, Issue:12

    Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Cel

2019
Anticancer Non-narcotic Opium Alkaloid Papaverine Suppresses Human Glioblastoma Cell Growth.
    Anticancer research, 2019, Volume: 39, Issue:12

    Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Cel

2019
Polyphyllin VII Promotes Apoptosis and Autophagic Cell Death via ROS-Inhibited AKT Activity, and Sensitizes Glioma Cells to Temozolomide.
    Oxidative medicine and cellular longevity, 2019, Volume: 2019

    Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Autophagic Cell Death; Brain Neoplasms; C

2019
Polyphyllin VII Promotes Apoptosis and Autophagic Cell Death via ROS-Inhibited AKT Activity, and Sensitizes Glioma Cells to Temozolomide.
    Oxidative medicine and cellular longevity, 2019, Volume: 2019

    Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Autophagic Cell Death; Brain Neoplasms; C

2019
Polyphyllin VII Promotes Apoptosis and Autophagic Cell Death via ROS-Inhibited AKT Activity, and Sensitizes Glioma Cells to Temozolomide.
    Oxidative medicine and cellular longevity, 2019, Volume: 2019

    Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Autophagic Cell Death; Brain Neoplasms; C

2019
Microarray expression profiles and bioinformatics analysis of mRNAs, lncRNAs, and circRNAs in the secondary temozolomide-resistant glioblastoma.
    Investigational new drugs, 2020, Volume: 38, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Computational Biology; Drug Resistance, Neoplasm

2020
Microarray expression profiles and bioinformatics analysis of mRNAs, lncRNAs, and circRNAs in the secondary temozolomide-resistant glioblastoma.
    Investigational new drugs, 2020, Volume: 38, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Computational Biology; Drug Resistance, Neoplasm

2020
Microarray expression profiles and bioinformatics analysis of mRNAs, lncRNAs, and circRNAs in the secondary temozolomide-resistant glioblastoma.
    Investigational new drugs, 2020, Volume: 38, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Computational Biology; Drug Resistance, Neoplasm

2020
Characterization of MGMT and EGFR protein expression in glioblastoma and association with survival.
    Journal of neuro-oncology, 2020, Volume: 146, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Biomarkers, Tumor; Brain Neoplasm

2020
Characterization of MGMT and EGFR protein expression in glioblastoma and association with survival.
    Journal of neuro-oncology, 2020, Volume: 146, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Biomarkers, Tumor; Brain Neoplasm

2020
Characterization of MGMT and EGFR protein expression in glioblastoma and association with survival.
    Journal of neuro-oncology, 2020, Volume: 146, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Biomarkers, Tumor; Brain Neoplasm

2020
Tumour Treating Fields (TTFields) in combination with lomustine and temozolomide in patients with newly diagnosed glioblastoma.
    Journal of cancer research and clinical oncology, 2020, Volume: 146, Issue:3

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Chemoradiotherapy; Com

2020
Tumour Treating Fields (TTFields) in combination with lomustine and temozolomide in patients with newly diagnosed glioblastoma.
    Journal of cancer research and clinical oncology, 2020, Volume: 146, Issue:3

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Chemoradiotherapy; Com

2020
Tumour Treating Fields (TTFields) in combination with lomustine and temozolomide in patients with newly diagnosed glioblastoma.
    Journal of cancer research and clinical oncology, 2020, Volume: 146, Issue:3

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Chemoradiotherapy; Com

2020
Accelerated hyperfractionated radiochemotherapy with temozolomide is equivalent to normofractionated radiochemotherapy in a retrospective analysis of patients with glioblastoma.
    Radiation oncology (London, England), 2019, Dec-12, Volume: 14, Issue:1

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chem

2019
Accelerated hyperfractionated radiochemotherapy with temozolomide is equivalent to normofractionated radiochemotherapy in a retrospective analysis of patients with glioblastoma.
    Radiation oncology (London, England), 2019, Dec-12, Volume: 14, Issue:1

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chem

2019
Accelerated hyperfractionated radiochemotherapy with temozolomide is equivalent to normofractionated radiochemotherapy in a retrospective analysis of patients with glioblastoma.
    Radiation oncology (London, England), 2019, Dec-12, Volume: 14, Issue:1

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chem

2019
Quantitative Proteomics Analysis Reveals Nuclear Perturbation in Human Glioma U87 Cells treated with Temozolomide.
    Cell biochemistry and function, 2020, Volume: 38, Issue:2

    Topics: Brain Neoplasms; Cell Line, Tumor; Cell Nucleus; Computational Biology; DNA Damage; DNA Repair; Glio

2020
Quantitative Proteomics Analysis Reveals Nuclear Perturbation in Human Glioma U87 Cells treated with Temozolomide.
    Cell biochemistry and function, 2020, Volume: 38, Issue:2

    Topics: Brain Neoplasms; Cell Line, Tumor; Cell Nucleus; Computational Biology; DNA Damage; DNA Repair; Glio

2020
Quantitative Proteomics Analysis Reveals Nuclear Perturbation in Human Glioma U87 Cells treated with Temozolomide.
    Cell biochemistry and function, 2020, Volume: 38, Issue:2

    Topics: Brain Neoplasms; Cell Line, Tumor; Cell Nucleus; Computational Biology; DNA Damage; DNA Repair; Glio

2020
Design, synthesis and cytotoxicity of the antitumor agent 1-azabicycles for chemoresistant glioblastoma cells.
    Investigational new drugs, 2020, Volume: 38, Issue:5

    Topics: Animals; Antineoplastic Agents; Apoptosis; Azabicyclo Compounds; Brain Neoplasms; Cell Cycle; Cell M

2020
Design, synthesis and cytotoxicity of the antitumor agent 1-azabicycles for chemoresistant glioblastoma cells.
    Investigational new drugs, 2020, Volume: 38, Issue:5

    Topics: Animals; Antineoplastic Agents; Apoptosis; Azabicyclo Compounds; Brain Neoplasms; Cell Cycle; Cell M

2020
Design, synthesis and cytotoxicity of the antitumor agent 1-azabicycles for chemoresistant glioblastoma cells.
    Investigational new drugs, 2020, Volume: 38, Issue:5

    Topics: Animals; Antineoplastic Agents; Apoptosis; Azabicyclo Compounds; Brain Neoplasms; Cell Cycle; Cell M

2020
Genomic and Phenotypic Characterization of a Broad Panel of Patient-Derived Xenografts Reflects the Diversity of Glioblastoma.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2020, 03-01, Volume: 26, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Animals; Antineoplastic Agents, Alkylating; Biomarkers, Tumor; Brain

2020
Genomic and Phenotypic Characterization of a Broad Panel of Patient-Derived Xenografts Reflects the Diversity of Glioblastoma.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2020, 03-01, Volume: 26, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Animals; Antineoplastic Agents, Alkylating; Biomarkers, Tumor; Brain

2020
Genomic and Phenotypic Characterization of a Broad Panel of Patient-Derived Xenografts Reflects the Diversity of Glioblastoma.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2020, 03-01, Volume: 26, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Animals; Antineoplastic Agents, Alkylating; Biomarkers, Tumor; Brain

2020
Survey of treatment recommendations for elderly patients with glioblastoma.
    Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico, 2020, Volume: 22, Issue:8

    Topics: Age Factors; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neoplasm

2020
Survey of treatment recommendations for elderly patients with glioblastoma.
    Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico, 2020, Volume: 22, Issue:8

    Topics: Age Factors; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neoplasm

2020
Survey of treatment recommendations for elderly patients with glioblastoma.
    Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico, 2020, Volume: 22, Issue:8

    Topics: Age Factors; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neoplasm

2020
IKBKE enhances TMZ-chemoresistance through upregulation of MGMT expression in glioblastoma.
    Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico, 2020, Volume: 22, Issue:8

    Topics: Animals; Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cell Movem

2020
IKBKE enhances TMZ-chemoresistance through upregulation of MGMT expression in glioblastoma.
    Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico, 2020, Volume: 22, Issue:8

    Topics: Animals; Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cell Movem

2020
IKBKE enhances TMZ-chemoresistance through upregulation of MGMT expression in glioblastoma.
    Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico, 2020, Volume: 22, Issue:8

    Topics: Animals; Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cell Movem

2020
Preclinical evaluation of binimetinib (MEK162) delivered via polymeric nanocarriers in combination with radiation and temozolomide in glioma.
    Journal of neuro-oncology, 2020, Volume: 146, Issue:2

    Topics: Antineoplastic Agents, Alkylating; Benzimidazoles; Blood-Brain Barrier; Brain Neoplasms; Cell Prolif

2020
Preclinical evaluation of binimetinib (MEK162) delivered via polymeric nanocarriers in combination with radiation and temozolomide in glioma.
    Journal of neuro-oncology, 2020, Volume: 146, Issue:2

    Topics: Antineoplastic Agents, Alkylating; Benzimidazoles; Blood-Brain Barrier; Brain Neoplasms; Cell Prolif

2020
Preclinical evaluation of binimetinib (MEK162) delivered via polymeric nanocarriers in combination with radiation and temozolomide in glioma.
    Journal of neuro-oncology, 2020, Volume: 146, Issue:2

    Topics: Antineoplastic Agents, Alkylating; Benzimidazoles; Blood-Brain Barrier; Brain Neoplasms; Cell Prolif

2020
Survival analysis of patients with glioblastoma treated by long-term administration of temozolomide.
    Medicine, 2020, Volume: 99, Issue:2

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant;

2020
Survival analysis of patients with glioblastoma treated by long-term administration of temozolomide.
    Medicine, 2020, Volume: 99, Issue:2

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant;

2020
Survival analysis of patients with glioblastoma treated by long-term administration of temozolomide.
    Medicine, 2020, Volume: 99, Issue:2

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant;

2020
A Key Role of DNA Damage-Inducible Transcript 4 (DDIT4) Connects Autophagy and GLUT3-Mediated Stemness To Desensitize Temozolomide Efficacy in Glioblastomas.
    Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics, 2020, Volume: 17, Issue:3

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Autophagy; Brain Neoplasms; Cell Line, T

2020
A Key Role of DNA Damage-Inducible Transcript 4 (DDIT4) Connects Autophagy and GLUT3-Mediated Stemness To Desensitize Temozolomide Efficacy in Glioblastomas.
    Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics, 2020, Volume: 17, Issue:3

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Autophagy; Brain Neoplasms; Cell Line, T

2020
A Key Role of DNA Damage-Inducible Transcript 4 (DDIT4) Connects Autophagy and GLUT3-Mediated Stemness To Desensitize Temozolomide Efficacy in Glioblastomas.
    Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics, 2020, Volume: 17, Issue:3

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Autophagy; Brain Neoplasms; Cell Line, T

2020
Short-term outcomes and predictors of post-surgical seizures in patients with supratentorial low-grade gliomas.
    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2020, Volume: 72

    Topics: Adult; Brain Neoplasms; Cohort Studies; Electroencephalography; Female; Glioma; Humans; Magnetic Res

2020
Short-term outcomes and predictors of post-surgical seizures in patients with supratentorial low-grade gliomas.
    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2020, Volume: 72

    Topics: Adult; Brain Neoplasms; Cohort Studies; Electroencephalography; Female; Glioma; Humans; Magnetic Res

2020
Short-term outcomes and predictors of post-surgical seizures in patients with supratentorial low-grade gliomas.
    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2020, Volume: 72

    Topics: Adult; Brain Neoplasms; Cohort Studies; Electroencephalography; Female; Glioma; Humans; Magnetic Res

2020
ShRNA-based POLD2 expression knockdown sensitizes glioblastoma to DNA-Damaging therapeutics.
    Cancer letters, 2020, 07-10, Volume: 482

    Topics: Animals; Brain Neoplasms; Cell Line, Tumor; Cell Movement; Cell Proliferation; DNA Polymerase III; D

2020
ShRNA-based POLD2 expression knockdown sensitizes glioblastoma to DNA-Damaging therapeutics.
    Cancer letters, 2020, 07-10, Volume: 482

    Topics: Animals; Brain Neoplasms; Cell Line, Tumor; Cell Movement; Cell Proliferation; DNA Polymerase III; D

2020
ShRNA-based POLD2 expression knockdown sensitizes glioblastoma to DNA-Damaging therapeutics.
    Cancer letters, 2020, 07-10, Volume: 482

    Topics: Animals; Brain Neoplasms; Cell Line, Tumor; Cell Movement; Cell Proliferation; DNA Polymerase III; D

2020
Widely metastatic glioblastoma with BRCA1 and ARID1A mutations: a case report.
    BMC cancer, 2020, Jan-20, Volume: 20, Issue:1

    Topics: Aged; Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; BRCA1 Protein; DNA Mismatch Repai

2020
Widely metastatic glioblastoma with BRCA1 and ARID1A mutations: a case report.
    BMC cancer, 2020, Jan-20, Volume: 20, Issue:1

    Topics: Aged; Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; BRCA1 Protein; DNA Mismatch Repai

2020
Widely metastatic glioblastoma with BRCA1 and ARID1A mutations: a case report.
    BMC cancer, 2020, Jan-20, Volume: 20, Issue:1

    Topics: Aged; Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; BRCA1 Protein; DNA Mismatch Repai

2020
Mitigating temozolomide resistance in glioblastoma via DNA damage-repair inhibition.
    Journal of the Royal Society, Interface, 2020, Volume: 17, Issue:162

    Topics: Brain Neoplasms; Cell Line, Tumor; Dacarbazine; DNA Damage; DNA Repair; Drug Resistance, Neoplasm; G

2020
Mitigating temozolomide resistance in glioblastoma via DNA damage-repair inhibition.
    Journal of the Royal Society, Interface, 2020, Volume: 17, Issue:162

    Topics: Brain Neoplasms; Cell Line, Tumor; Dacarbazine; DNA Damage; DNA Repair; Drug Resistance, Neoplasm; G

2020
Mitigating temozolomide resistance in glioblastoma via DNA damage-repair inhibition.
    Journal of the Royal Society, Interface, 2020, Volume: 17, Issue:162

    Topics: Brain Neoplasms; Cell Line, Tumor; Dacarbazine; DNA Damage; DNA Repair; Drug Resistance, Neoplasm; G

2020
Hypertension and proteinuria as clinical biomarkers of response to bevacizumab in glioblastoma patients.
    Journal of neuro-oncology, 2020, Volume: 147, Issue:1

    Topics: Adult; Aged; Angiogenesis Inhibitors; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Immu

2020
Hypertension and proteinuria as clinical biomarkers of response to bevacizumab in glioblastoma patients.
    Journal of neuro-oncology, 2020, Volume: 147, Issue:1

    Topics: Adult; Aged; Angiogenesis Inhibitors; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Immu

2020
Hypertension and proteinuria as clinical biomarkers of response to bevacizumab in glioblastoma patients.
    Journal of neuro-oncology, 2020, Volume: 147, Issue:1

    Topics: Adult; Aged; Angiogenesis Inhibitors; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Immu

2020
Infiltration of CD163-positive macrophages in glioma tissues after treatment with anti-PD-L1 antibody and role of PI3Kγ inhibitor as a combination therapy with anti-PD-L1 antibody in in vivo model using temozolomide-resistant murine glioma-initiating cell
    Brain tumor pathology, 2020, Volume: 37, Issue:2

    Topics: Animals; Antibodies; Antigens, CD; Antigens, Differentiation, Myelomonocytic; B7-H1 Antigen; Brain N

2020
Infiltration of CD163-positive macrophages in glioma tissues after treatment with anti-PD-L1 antibody and role of PI3Kγ inhibitor as a combination therapy with anti-PD-L1 antibody in in vivo model using temozolomide-resistant murine glioma-initiating cell
    Brain tumor pathology, 2020, Volume: 37, Issue:2

    Topics: Animals; Antibodies; Antigens, CD; Antigens, Differentiation, Myelomonocytic; B7-H1 Antigen; Brain N

2020
Infiltration of CD163-positive macrophages in glioma tissues after treatment with anti-PD-L1 antibody and role of PI3Kγ inhibitor as a combination therapy with anti-PD-L1 antibody in in vivo model using temozolomide-resistant murine glioma-initiating cell
    Brain tumor pathology, 2020, Volume: 37, Issue:2

    Topics: Animals; Antibodies; Antigens, CD; Antigens, Differentiation, Myelomonocytic; B7-H1 Antigen; Brain N

2020
Evaluation of the Prognosis of Neuroglioma Based on Dynamic Magnetic Resonance Enhancement.
    World neurosurgery, 2020, Volume: 138

    Topics: Antineoplastic Agents, Alkylating; Brain Edema; Brain Neoplasms; Chemotherapy, Adjuvant; Contrast Me

2020
Evaluation of the Prognosis of Neuroglioma Based on Dynamic Magnetic Resonance Enhancement.
    World neurosurgery, 2020, Volume: 138

    Topics: Antineoplastic Agents, Alkylating; Brain Edema; Brain Neoplasms; Chemotherapy, Adjuvant; Contrast Me

2020
Evaluation of the Prognosis of Neuroglioma Based on Dynamic Magnetic Resonance Enhancement.
    World neurosurgery, 2020, Volume: 138

    Topics: Antineoplastic Agents, Alkylating; Brain Edema; Brain Neoplasms; Chemotherapy, Adjuvant; Contrast Me

2020
Deleterious impact of a generic temozolomide formulation compared with brand-name product on the kinetic of platelet concentration and survival in newly diagnosed glioblastoma.
    Fundamental & clinical pharmacology, 2020, Volume: 34, Issue:4

    Topics: Antineoplastic Agents, Alkylating; Blood Platelets; Brain Neoplasms; Drug Compounding; Drugs, Generi

2020
Deleterious impact of a generic temozolomide formulation compared with brand-name product on the kinetic of platelet concentration and survival in newly diagnosed glioblastoma.
    Fundamental & clinical pharmacology, 2020, Volume: 34, Issue:4

    Topics: Antineoplastic Agents, Alkylating; Blood Platelets; Brain Neoplasms; Drug Compounding; Drugs, Generi

2020
Deleterious impact of a generic temozolomide formulation compared with brand-name product on the kinetic of platelet concentration and survival in newly diagnosed glioblastoma.
    Fundamental & clinical pharmacology, 2020, Volume: 34, Issue:4

    Topics: Antineoplastic Agents, Alkylating; Blood Platelets; Brain Neoplasms; Drug Compounding; Drugs, Generi

2020
Temozolomide plus whole brain radiotherapy for the treatment of non-small-cell lung cancer patients with brain metastases: A protocol of an updated systematic review and meta-analysis.
    Medicine, 2020, Volume: 99, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Carcinoma, Non-Small-Cell Lung; Humans; Lung Neo

2020
Temozolomide plus whole brain radiotherapy for the treatment of non-small-cell lung cancer patients with brain metastases: A protocol of an updated systematic review and meta-analysis.
    Medicine, 2020, Volume: 99, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Carcinoma, Non-Small-Cell Lung; Humans; Lung Neo

2020
Temozolomide plus whole brain radiotherapy for the treatment of non-small-cell lung cancer patients with brain metastases: A protocol of an updated systematic review and meta-analysis.
    Medicine, 2020, Volume: 99, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Carcinoma, Non-Small-Cell Lung; Humans; Lung Neo

2020
Identifying Disparities in Care in Treating Glioblastoma: A Retrospective Cohort Study of Patients Treated at a Safety-net Versus Private Hospital Setting.
    World neurosurgery, 2020, Volume: 137

    Topics: Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy, Adjuvant; Chemotherapy,

2020
Identifying Disparities in Care in Treating Glioblastoma: A Retrospective Cohort Study of Patients Treated at a Safety-net Versus Private Hospital Setting.
    World neurosurgery, 2020, Volume: 137

    Topics: Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy, Adjuvant; Chemotherapy,

2020
Identifying Disparities in Care in Treating Glioblastoma: A Retrospective Cohort Study of Patients Treated at a Safety-net Versus Private Hospital Setting.
    World neurosurgery, 2020, Volume: 137

    Topics: Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy, Adjuvant; Chemotherapy,

2020
First-line bevacizumab contributes to survival improvement in glioblastoma patients complementary to temozolomide.
    Journal of neuro-oncology, 2020, Volume: 146, Issue:3

    Topics: Aged; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Immunological; Antineoplastic Combin

2020
First-line bevacizumab contributes to survival improvement in glioblastoma patients complementary to temozolomide.
    Journal of neuro-oncology, 2020, Volume: 146, Issue:3

    Topics: Aged; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Immunological; Antineoplastic Combin

2020
First-line bevacizumab contributes to survival improvement in glioblastoma patients complementary to temozolomide.
    Journal of neuro-oncology, 2020, Volume: 146, Issue:3

    Topics: Aged; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Immunological; Antineoplastic Combin

2020
A Common Rule for Resection of Glioblastoma in the Molecular Era.
    JAMA oncology, 2020, 04-01, Volume: 6, Issue:4

    Topics: Brain Neoplasms; Glioblastoma; Humans; Temozolomide

2020
A Common Rule for Resection of Glioblastoma in the Molecular Era.
    JAMA oncology, 2020, 04-01, Volume: 6, Issue:4

    Topics: Brain Neoplasms; Glioblastoma; Humans; Temozolomide

2020
A Common Rule for Resection of Glioblastoma in the Molecular Era.
    JAMA oncology, 2020, 04-01, Volume: 6, Issue:4

    Topics: Brain Neoplasms; Glioblastoma; Humans; Temozolomide

2020
Temozolomide for patients with wild-type isocitrate dehydrogenase (IDH) 1 glioblastoma using propensity score matching.
    Clinical neurology and neurosurgery, 2020, Volume: 191

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Case-Control Studies; Chemoradiothe

2020
Temozolomide for patients with wild-type isocitrate dehydrogenase (IDH) 1 glioblastoma using propensity score matching.
    Clinical neurology and neurosurgery, 2020, Volume: 191

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Case-Control Studies; Chemoradiothe

2020
Temozolomide for patients with wild-type isocitrate dehydrogenase (IDH) 1 glioblastoma using propensity score matching.
    Clinical neurology and neurosurgery, 2020, Volume: 191

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Case-Control Studies; Chemoradiothe

2020
Superiority of temozolomide over radiotherapy for elderly patients with RTK II methylation class, MGMT promoter methylated malignant astrocytoma.
    Neuro-oncology, 2020, 08-17, Volume: 22, Issue:8

    Topics: Aged; Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neoplasms; DNA Copy Number Variations; D

2020
Superiority of temozolomide over radiotherapy for elderly patients with RTK II methylation class, MGMT promoter methylated malignant astrocytoma.
    Neuro-oncology, 2020, 08-17, Volume: 22, Issue:8

    Topics: Aged; Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neoplasms; DNA Copy Number Variations; D

2020
Superiority of temozolomide over radiotherapy for elderly patients with RTK II methylation class, MGMT promoter methylated malignant astrocytoma.
    Neuro-oncology, 2020, 08-17, Volume: 22, Issue:8

    Topics: Aged; Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neoplasms; DNA Copy Number Variations; D

2020
EGFRvIII upregulates DNA mismatch repair resulting in increased temozolomide sensitivity of MGMT promoter methylated glioblastoma.
    Oncogene, 2020, Volume: 39, Issue:15

    Topics: Animals; Brain Neoplasms; Cell Line, Tumor; Chemoradiotherapy; Cohort Studies; DNA Methylation; DNA

2020
EGFRvIII upregulates DNA mismatch repair resulting in increased temozolomide sensitivity of MGMT promoter methylated glioblastoma.
    Oncogene, 2020, Volume: 39, Issue:15

    Topics: Animals; Brain Neoplasms; Cell Line, Tumor; Chemoradiotherapy; Cohort Studies; DNA Methylation; DNA

2020
EGFRvIII upregulates DNA mismatch repair resulting in increased temozolomide sensitivity of MGMT promoter methylated glioblastoma.
    Oncogene, 2020, Volume: 39, Issue:15

    Topics: Animals; Brain Neoplasms; Cell Line, Tumor; Chemoradiotherapy; Cohort Studies; DNA Methylation; DNA

2020
Overexpression miR-486-3p Promoted by Allicin Enhances Temozolomide Sensitivity in Glioblastoma Via Targeting MGMT.
    Neuromolecular medicine, 2020, Volume: 22, Issue:3

    Topics: Adult; Animals; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Disulfides; DNA Modification Methylase

2020
Overexpression miR-486-3p Promoted by Allicin Enhances Temozolomide Sensitivity in Glioblastoma Via Targeting MGMT.
    Neuromolecular medicine, 2020, Volume: 22, Issue:3

    Topics: Adult; Animals; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Disulfides; DNA Modification Methylase

2020
Overexpression miR-486-3p Promoted by Allicin Enhances Temozolomide Sensitivity in Glioblastoma Via Targeting MGMT.
    Neuromolecular medicine, 2020, Volume: 22, Issue:3

    Topics: Adult; Animals; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Disulfides; DNA Modification Methylase

2020
Revealing the epigenetic effect of temozolomide on glioblastoma cell lines in therapeutic conditions.
    PloS one, 2020, Volume: 15, Issue:2

    Topics: 5-Methylcytosine; Brain Neoplasms; Cell Line, Tumor; DNA Methylation; DNA Modification Methylases; D

2020
Revealing the epigenetic effect of temozolomide on glioblastoma cell lines in therapeutic conditions.
    PloS one, 2020, Volume: 15, Issue:2

    Topics: 5-Methylcytosine; Brain Neoplasms; Cell Line, Tumor; DNA Methylation; DNA Modification Methylases; D

2020
Revealing the epigenetic effect of temozolomide on glioblastoma cell lines in therapeutic conditions.
    PloS one, 2020, Volume: 15, Issue:2

    Topics: 5-Methylcytosine; Brain Neoplasms; Cell Line, Tumor; DNA Methylation; DNA Modification Methylases; D

2020
Wnt-mediated endothelial transformation into mesenchymal stem cell-like cells induces chemoresistance in glioblastoma.
    Science translational medicine, 2020, 02-26, Volume: 12, Issue:532

    Topics: Animals; Brain Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; Endothelial Cells; Glioblasto

2020
Wnt-mediated endothelial transformation into mesenchymal stem cell-like cells induces chemoresistance in glioblastoma.
    Science translational medicine, 2020, 02-26, Volume: 12, Issue:532

    Topics: Animals; Brain Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; Endothelial Cells; Glioblasto

2020
Wnt-mediated endothelial transformation into mesenchymal stem cell-like cells induces chemoresistance in glioblastoma.
    Science translational medicine, 2020, 02-26, Volume: 12, Issue:532

    Topics: Animals; Brain Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; Endothelial Cells; Glioblasto

2020
Calpain suppresses cell growth and invasion of glioblastoma multiforme by producing the cleavage of filamin A.
    International journal of clinical oncology, 2020, Volume: 25, Issue:6

    Topics: Biomarkers, Tumor; Brain Neoplasms; Calpain; Cell Line, Tumor; Cell Movement; Cell Proliferation; Ce

2020
Calpain suppresses cell growth and invasion of glioblastoma multiforme by producing the cleavage of filamin A.
    International journal of clinical oncology, 2020, Volume: 25, Issue:6

    Topics: Biomarkers, Tumor; Brain Neoplasms; Calpain; Cell Line, Tumor; Cell Movement; Cell Proliferation; Ce

2020
Calpain suppresses cell growth and invasion of glioblastoma multiforme by producing the cleavage of filamin A.
    International journal of clinical oncology, 2020, Volume: 25, Issue:6

    Topics: Biomarkers, Tumor; Brain Neoplasms; Calpain; Cell Line, Tumor; Cell Movement; Cell Proliferation; Ce

2020
Neurological Impairments in Mice Subjected to Irradiation and Chemotherapy.
    Radiation research, 2020, Volume: 193, Issue:5

    Topics: Animals; Anxiety; Behavior, Animal; Brain Neoplasms; CA1 Region, Hippocampal; Combined Modality Ther

2020
Neurological Impairments in Mice Subjected to Irradiation and Chemotherapy.
    Radiation research, 2020, Volume: 193, Issue:5

    Topics: Animals; Anxiety; Behavior, Animal; Brain Neoplasms; CA1 Region, Hippocampal; Combined Modality Ther

2020
Neurological Impairments in Mice Subjected to Irradiation and Chemotherapy.
    Radiation research, 2020, Volume: 193, Issue:5

    Topics: Animals; Anxiety; Behavior, Animal; Brain Neoplasms; CA1 Region, Hippocampal; Combined Modality Ther

2020
Major response to temozolomide as first-line treatment for newly-diagnosed DDR2-mutated glioblastoma: A case report.
    Revue neurologique, 2020, Volume: 176, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Discoidin Domain Rece

2020
Major response to temozolomide as first-line treatment for newly-diagnosed DDR2-mutated glioblastoma: A case report.
    Revue neurologique, 2020, Volume: 176, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Discoidin Domain Rece

2020
Major response to temozolomide as first-line treatment for newly-diagnosed DDR2-mutated glioblastoma: A case report.
    Revue neurologique, 2020, Volume: 176, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Discoidin Domain Rece

2020
A troublesome burden, the amplification of EGFR in glioblastoma!
    Neuro-oncology, 2020, 05-15, Volume: 22, Issue:5

    Topics: Antibodies, Monoclonal, Humanized; Brain Neoplasms; ErbB Receptors; Glioblastoma; Humans; Lomustine;

2020
A troublesome burden, the amplification of EGFR in glioblastoma!
    Neuro-oncology, 2020, 05-15, Volume: 22, Issue:5

    Topics: Antibodies, Monoclonal, Humanized; Brain Neoplasms; ErbB Receptors; Glioblastoma; Humans; Lomustine;

2020
A troublesome burden, the amplification of EGFR in glioblastoma!
    Neuro-oncology, 2020, 05-15, Volume: 22, Issue:5

    Topics: Antibodies, Monoclonal, Humanized; Brain Neoplasms; ErbB Receptors; Glioblastoma; Humans; Lomustine;

2020
STAT3 inhibition induced temozolomide-resistant glioblastoma apoptosis via triggering mitochondrial STAT3 translocation and respiratory chain dysfunction.
    Cellular signalling, 2020, Volume: 71

    Topics: Animals; Apoptosis; Apoptosis Regulatory Proteins; Brain Neoplasms; Cell Line, Tumor; Cell Nucleus;

2020
STAT3 inhibition induced temozolomide-resistant glioblastoma apoptosis via triggering mitochondrial STAT3 translocation and respiratory chain dysfunction.
    Cellular signalling, 2020, Volume: 71

    Topics: Animals; Apoptosis; Apoptosis Regulatory Proteins; Brain Neoplasms; Cell Line, Tumor; Cell Nucleus;

2020
STAT3 inhibition induced temozolomide-resistant glioblastoma apoptosis via triggering mitochondrial STAT3 translocation and respiratory chain dysfunction.
    Cellular signalling, 2020, Volume: 71

    Topics: Animals; Apoptosis; Apoptosis Regulatory Proteins; Brain Neoplasms; Cell Line, Tumor; Cell Nucleus;

2020
MGMT promoter methylation level in newly diagnosed low-grade glioma is a predictor of hypermutation at recurrence.
    Neuro-oncology, 2020, 11-26, Volume: 22, Issue:11

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; DNA Methylation; DNA Modification Methylases; DN

2020
MGMT promoter methylation level in newly diagnosed low-grade glioma is a predictor of hypermutation at recurrence.
    Neuro-oncology, 2020, 11-26, Volume: 22, Issue:11

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; DNA Methylation; DNA Modification Methylases; DN

2020
MGMT promoter methylation level in newly diagnosed low-grade glioma is a predictor of hypermutation at recurrence.
    Neuro-oncology, 2020, 11-26, Volume: 22, Issue:11

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; DNA Methylation; DNA Modification Methylases; DN

2020
Riluzole enhances the antitumor effects of temozolomide via suppression of MGMT expression in glioblastoma.
    Journal of neurosurgery, 2020, Mar-13, Volume: 134, Issue:3

    Topics: Animals; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Brain Ne

2020
Riluzole enhances the antitumor effects of temozolomide via suppression of MGMT expression in glioblastoma.
    Journal of neurosurgery, 2020, Mar-13, Volume: 134, Issue:3

    Topics: Animals; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Brain Ne

2020
Riluzole enhances the antitumor effects of temozolomide via suppression of MGMT expression in glioblastoma.
    Journal of neurosurgery, 2020, Mar-13, Volume: 134, Issue:3

    Topics: Animals; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Brain Ne

2020
A steroidal saponin form Paris vietnamensis (Takht.) reverses temozolomide resistance in glioblastoma cells via inducing apoptosis through ROS/PI3K/Akt pathway.
    Bioscience trends, 2020, May-21, Volume: 14, Issue:2

    Topics: Acetylcysteine; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; A

2020
A steroidal saponin form Paris vietnamensis (Takht.) reverses temozolomide resistance in glioblastoma cells via inducing apoptosis through ROS/PI3K/Akt pathway.
    Bioscience trends, 2020, May-21, Volume: 14, Issue:2

    Topics: Acetylcysteine; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; A

2020
A steroidal saponin form Paris vietnamensis (Takht.) reverses temozolomide resistance in glioblastoma cells via inducing apoptosis through ROS/PI3K/Akt pathway.
    Bioscience trends, 2020, May-21, Volume: 14, Issue:2

    Topics: Acetylcysteine; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; A

2020
The clinical, radiological, and immunohistochemical characteristics and outcomes of primary intracranial gliosarcoma: a retrospective single-centre study.
    Neurosurgical review, 2021, Volume: 44, Issue:2

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Female; Gliosarcoma; H

2021
The clinical, radiological, and immunohistochemical characteristics and outcomes of primary intracranial gliosarcoma: a retrospective single-centre study.
    Neurosurgical review, 2021, Volume: 44, Issue:2

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Female; Gliosarcoma; H

2021
The clinical, radiological, and immunohistochemical characteristics and outcomes of primary intracranial gliosarcoma: a retrospective single-centre study.
    Neurosurgical review, 2021, Volume: 44, Issue:2

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Female; Gliosarcoma; H

2021
Intranasal Delivery of Immunotherapeutic Nanoformulations for Treatment of Glioma Through in situ Activation of Immune Response.
    International journal of nanomedicine, 2020, Volume: 15

    Topics: Administration, Intranasal; Animals; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Drug Del

2020
Intranasal Delivery of Immunotherapeutic Nanoformulations for Treatment of Glioma Through in situ Activation of Immune Response.
    International journal of nanomedicine, 2020, Volume: 15

    Topics: Administration, Intranasal; Animals; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Drug Del

2020
Intranasal Delivery of Immunotherapeutic Nanoformulations for Treatment of Glioma Through in situ Activation of Immune Response.
    International journal of nanomedicine, 2020, Volume: 15

    Topics: Administration, Intranasal; Animals; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Drug Del

2020
Epigenetic preconditioning with decitabine sensitizes glioblastoma to temozolomide via induction of MLH1.
    Journal of neuro-oncology, 2020, Volume: 147, Issue:3

    Topics: Antineoplastic Agents; Brain Neoplasms; Cell Line, Tumor; Decitabine; Epigenesis, Genetic; Glioblast

2020
Epigenetic preconditioning with decitabine sensitizes glioblastoma to temozolomide via induction of MLH1.
    Journal of neuro-oncology, 2020, Volume: 147, Issue:3

    Topics: Antineoplastic Agents; Brain Neoplasms; Cell Line, Tumor; Decitabine; Epigenesis, Genetic; Glioblast

2020
Epigenetic preconditioning with decitabine sensitizes glioblastoma to temozolomide via induction of MLH1.
    Journal of neuro-oncology, 2020, Volume: 147, Issue:3

    Topics: Antineoplastic Agents; Brain Neoplasms; Cell Line, Tumor; Decitabine; Epigenesis, Genetic; Glioblast

2020
Exosome-mediated transfer of circRNA CircNFIX enhances temozolomide resistance in glioma.
    Cancer letters, 2020, 06-01, Volume: 479

    Topics: Animals; Brain Neoplasms; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cell Survival; Drug R

2020
Exosome-mediated transfer of circRNA CircNFIX enhances temozolomide resistance in glioma.
    Cancer letters, 2020, 06-01, Volume: 479

    Topics: Animals; Brain Neoplasms; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cell Survival; Drug R

2020
Exosome-mediated transfer of circRNA CircNFIX enhances temozolomide resistance in glioma.
    Cancer letters, 2020, 06-01, Volume: 479

    Topics: Animals; Brain Neoplasms; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cell Survival; Drug R

2020
MicroRNA-155-3p promotes glioma progression and temozolomide resistance by targeting Six1.
    Journal of cellular and molecular medicine, 2020, Volume: 24, Issue:9

    Topics: Animals; Base Sequence; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Disease Progression;

2020
MicroRNA-155-3p promotes glioma progression and temozolomide resistance by targeting Six1.
    Journal of cellular and molecular medicine, 2020, Volume: 24, Issue:9

    Topics: Animals; Base Sequence; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Disease Progression;

2020
MicroRNA-155-3p promotes glioma progression and temozolomide resistance by targeting Six1.
    Journal of cellular and molecular medicine, 2020, Volume: 24, Issue:9

    Topics: Animals; Base Sequence; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Disease Progression;

2020
All-stage precisional glioma targeted therapy enabled by a well-designed D-peptide.
    Theranostics, 2020, Volume: 10, Issue:9

    Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Cell Line, Tumor; Drug Carriers; Endoplasmic Reticu

2020
All-stage precisional glioma targeted therapy enabled by a well-designed D-peptide.
    Theranostics, 2020, Volume: 10, Issue:9

    Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Cell Line, Tumor; Drug Carriers; Endoplasmic Reticu

2020
All-stage precisional glioma targeted therapy enabled by a well-designed D-peptide.
    Theranostics, 2020, Volume: 10, Issue:9

    Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Cell Line, Tumor; Drug Carriers; Endoplasmic Reticu

2020
Control of brain tumor growth by reactivating myeloid cells with niacin.
    Science translational medicine, 2020, 04-01, Volume: 12, Issue:537

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Glioblastoma; Humans; Mice; Neoplastic

2020
Control of brain tumor growth by reactivating myeloid cells with niacin.
    Science translational medicine, 2020, 04-01, Volume: 12, Issue:537

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Glioblastoma; Humans; Mice; Neoplastic

2020
Control of brain tumor growth by reactivating myeloid cells with niacin.
    Science translational medicine, 2020, 04-01, Volume: 12, Issue:537

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Glioblastoma; Humans; Mice; Neoplastic

2020
[Dosimetry of tumor treating fields: energy per unit correlates with oncological endpoints in patients with glioblastoma in the EF-14 trial].
    Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 2020, Volume: 196, Issue:6

    Topics: Brain Neoplasms; Glioblastoma; Humans; Radiometry; Temozolomide

2020
[Dosimetry of tumor treating fields: energy per unit correlates with oncological endpoints in patients with glioblastoma in the EF-14 trial].
    Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 2020, Volume: 196, Issue:6

    Topics: Brain Neoplasms; Glioblastoma; Humans; Radiometry; Temozolomide

2020
[Dosimetry of tumor treating fields: energy per unit correlates with oncological endpoints in patients with glioblastoma in the EF-14 trial].
    Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 2020, Volume: 196, Issue:6

    Topics: Brain Neoplasms; Glioblastoma; Humans; Radiometry; Temozolomide

2020
miR-149 rs2292832 C allele enhances the cytotoxic effect of temozolomide against glioma cells.
    Neuroreport, 2020, 04-08, Volume: 31, Issue:6

    Topics: Alleles; Antineoplastic Agents; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Ce

2020
miR-149 rs2292832 C allele enhances the cytotoxic effect of temozolomide against glioma cells.
    Neuroreport, 2020, 04-08, Volume: 31, Issue:6

    Topics: Alleles; Antineoplastic Agents; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Ce

2020
miR-149 rs2292832 C allele enhances the cytotoxic effect of temozolomide against glioma cells.
    Neuroreport, 2020, 04-08, Volume: 31, Issue:6

    Topics: Alleles; Antineoplastic Agents; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Ce

2020
Micro-RNA29b enhances the sensitivity of glioblastoma multiforme cells to temozolomide by promoting autophagy.
    Anatomical record (Hoboken, N.J. : 2007), 2021, Volume: 304, Issue:2

    Topics: Animals; Antineoplastic Agents, Alkylating; Apoptosis; Autophagy; Brain Neoplasms; Cell Line, Tumor;

2021
Micro-RNA29b enhances the sensitivity of glioblastoma multiforme cells to temozolomide by promoting autophagy.
    Anatomical record (Hoboken, N.J. : 2007), 2021, Volume: 304, Issue:2

    Topics: Animals; Antineoplastic Agents, Alkylating; Apoptosis; Autophagy; Brain Neoplasms; Cell Line, Tumor;

2021
Micro-RNA29b enhances the sensitivity of glioblastoma multiforme cells to temozolomide by promoting autophagy.
    Anatomical record (Hoboken, N.J. : 2007), 2021, Volume: 304, Issue:2

    Topics: Animals; Antineoplastic Agents, Alkylating; Apoptosis; Autophagy; Brain Neoplasms; Cell Line, Tumor;

2021
CDK4/6 inhibition suppresses tumour growth and enhances the effect of temozolomide in glioma cells.
    Journal of cellular and molecular medicine, 2020, Volume: 24, Issue:9

    Topics: Aminopyridines; Animals; Apoptosis; Benzimidazoles; Brain Neoplasms; Cell Line, Tumor; Cell Prolifer

2020
CDK4/6 inhibition suppresses tumour growth and enhances the effect of temozolomide in glioma cells.
    Journal of cellular and molecular medicine, 2020, Volume: 24, Issue:9

    Topics: Aminopyridines; Animals; Apoptosis; Benzimidazoles; Brain Neoplasms; Cell Line, Tumor; Cell Prolifer

2020
CDK4/6 inhibition suppresses tumour growth and enhances the effect of temozolomide in glioma cells.
    Journal of cellular and molecular medicine, 2020, Volume: 24, Issue:9

    Topics: Aminopyridines; Animals; Apoptosis; Benzimidazoles; Brain Neoplasms; Cell Line, Tumor; Cell Prolifer

2020
Downregulation of SNRPG induces cell cycle arrest and sensitizes human glioblastoma cells to temozolomide by targeting Myc through a p53-dependent signaling pathway.
    Cancer biology & medicine, 2020, 02-15, Volume: 17, Issue:1

    Topics: Adult; Aged; Animals; Brain; Brain Neoplasms; Cell Line, Tumor; Down-Regulation; Drug Resistance, Ne

2020
Downregulation of SNRPG induces cell cycle arrest and sensitizes human glioblastoma cells to temozolomide by targeting Myc through a p53-dependent signaling pathway.
    Cancer biology & medicine, 2020, 02-15, Volume: 17, Issue:1

    Topics: Adult; Aged; Animals; Brain; Brain Neoplasms; Cell Line, Tumor; Down-Regulation; Drug Resistance, Ne

2020
Downregulation of SNRPG induces cell cycle arrest and sensitizes human glioblastoma cells to temozolomide by targeting Myc through a p53-dependent signaling pathway.
    Cancer biology & medicine, 2020, 02-15, Volume: 17, Issue:1

    Topics: Adult; Aged; Animals; Brain; Brain Neoplasms; Cell Line, Tumor; Down-Regulation; Drug Resistance, Ne

2020
Reinforcement learning for optimal scheduling of Glioblastoma treatment with Temozolomide.
    Computer methods and programs in biomedicine, 2020, Volume: 193

    Topics: Adult; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor;

2020
Reinforcement learning for optimal scheduling of Glioblastoma treatment with Temozolomide.
    Computer methods and programs in biomedicine, 2020, Volume: 193

    Topics: Adult; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor;

2020
Reinforcement learning for optimal scheduling of Glioblastoma treatment with Temozolomide.
    Computer methods and programs in biomedicine, 2020, Volume: 193

    Topics: Adult; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor;

2020
Targeting the ABC transporter ABCB5 sensitizes glioblastoma to temozolomide-induced apoptosis through a cell-cycle checkpoint regulation mechanism.
    The Journal of biological chemistry, 2020, 05-29, Volume: 295, Issue:22

    Topics: Animals; Antibodies, Neoplasm; Apoptosis; ATP Binding Cassette Transporter, Subfamily B; Brain Neopl

2020
Targeting the ABC transporter ABCB5 sensitizes glioblastoma to temozolomide-induced apoptosis through a cell-cycle checkpoint regulation mechanism.
    The Journal of biological chemistry, 2020, 05-29, Volume: 295, Issue:22

    Topics: Animals; Antibodies, Neoplasm; Apoptosis; ATP Binding Cassette Transporter, Subfamily B; Brain Neopl

2020
Targeting the ABC transporter ABCB5 sensitizes glioblastoma to temozolomide-induced apoptosis through a cell-cycle checkpoint regulation mechanism.
    The Journal of biological chemistry, 2020, 05-29, Volume: 295, Issue:22

    Topics: Animals; Antibodies, Neoplasm; Apoptosis; ATP Binding Cassette Transporter, Subfamily B; Brain Neopl

2020
Mechanisms and therapeutic implications of hypermutation in gliomas.
    Nature, 2020, Volume: 580, Issue:7804

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; DNA Mismatch Repair; Gene Frequency; Ge

2020
Mechanisms and therapeutic implications of hypermutation in gliomas.
    Nature, 2020, Volume: 580, Issue:7804

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; DNA Mismatch Repair; Gene Frequency; Ge

2020
Mechanisms and therapeutic implications of hypermutation in gliomas.
    Nature, 2020, Volume: 580, Issue:7804

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; DNA Mismatch Repair; Gene Frequency; Ge

2020
The CXCL12/CXCR4 axis confers temozolomide resistance to human glioblastoma cells via up-regulation of FOXM1.
    Journal of the neurological sciences, 2020, Jul-15, Volume: 414

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Chemokine CXCL12; Drug Resista

2020
The CXCL12/CXCR4 axis confers temozolomide resistance to human glioblastoma cells via up-regulation of FOXM1.
    Journal of the neurological sciences, 2020, Jul-15, Volume: 414

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Chemokine CXCL12; Drug Resista

2020
The CXCL12/CXCR4 axis confers temozolomide resistance to human glioblastoma cells via up-regulation of FOXM1.
    Journal of the neurological sciences, 2020, Jul-15, Volume: 414

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Chemokine CXCL12; Drug Resista

2020
Entry and exit of chemotherapeutically-promoted cellular dormancy in glioblastoma cells is differentially affected by the chemokines CXCL12, CXCL16, and CX3CL1.
    Oncogene, 2020, Volume: 39, Issue:22

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Chemokine

2020
Entry and exit of chemotherapeutically-promoted cellular dormancy in glioblastoma cells is differentially affected by the chemokines CXCL12, CXCL16, and CX3CL1.
    Oncogene, 2020, Volume: 39, Issue:22

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Chemokine

2020
Entry and exit of chemotherapeutically-promoted cellular dormancy in glioblastoma cells is differentially affected by the chemokines CXCL12, CXCL16, and CX3CL1.
    Oncogene, 2020, Volume: 39, Issue:22

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Chemokine

2020
Chemoradiation in elderly patients with glioblastoma from the multi-institutional GBM-molRPA cohort: is short-course radiotherapy enough or is it a matter of selection?
    Journal of neuro-oncology, 2020, Volume: 148, Issue:1

    Topics: Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Coho

2020
Chemoradiation in elderly patients with glioblastoma from the multi-institutional GBM-molRPA cohort: is short-course radiotherapy enough or is it a matter of selection?
    Journal of neuro-oncology, 2020, Volume: 148, Issue:1

    Topics: Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Coho

2020
Chemoradiation in elderly patients with glioblastoma from the multi-institutional GBM-molRPA cohort: is short-course radiotherapy enough or is it a matter of selection?
    Journal of neuro-oncology, 2020, Volume: 148, Issue:1

    Topics: Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Coho

2020
The limitations of targeting MEK signalling in Glioblastoma therapy.
    Scientific reports, 2020, 05-04, Volume: 10, Issue:1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Brain Neoplasms; Cell Adhesion; Cell Deat

2020
The limitations of targeting MEK signalling in Glioblastoma therapy.
    Scientific reports, 2020, 05-04, Volume: 10, Issue:1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Brain Neoplasms; Cell Adhesion; Cell Deat

2020
The limitations of targeting MEK signalling in Glioblastoma therapy.
    Scientific reports, 2020, 05-04, Volume: 10, Issue:1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Brain Neoplasms; Cell Adhesion; Cell Deat

2020
Leucine-rich repeat containing 4 act as an autophagy inhibitor that restores sensitivity of glioblastoma to temozolomide.
    Oncogene, 2020, Volume: 39, Issue:23

    Topics: Animals; Antineoplastic Agents, Alkylating; Autophagy; Brain Neoplasms; Cell Line, Tumor; Drug Resis

2020
Leucine-rich repeat containing 4 act as an autophagy inhibitor that restores sensitivity of glioblastoma to temozolomide.
    Oncogene, 2020, Volume: 39, Issue:23

    Topics: Animals; Antineoplastic Agents, Alkylating; Autophagy; Brain Neoplasms; Cell Line, Tumor; Drug Resis

2020
Leucine-rich repeat containing 4 act as an autophagy inhibitor that restores sensitivity of glioblastoma to temozolomide.
    Oncogene, 2020, Volume: 39, Issue:23

    Topics: Animals; Antineoplastic Agents, Alkylating; Autophagy; Brain Neoplasms; Cell Line, Tumor; Drug Resis

2020
Feasibility of hippocampus-sparing VMAT for newly diagnosed glioblastoma treated by chemoradiation: pattern of failure analysis.
    Radiation oncology (London, England), 2020, May-06, Volume: 15, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Brain Neoplasms; Chemoradiotherapy; Female; Glioblastoma; Hippocampu

2020
Feasibility of hippocampus-sparing VMAT for newly diagnosed glioblastoma treated by chemoradiation: pattern of failure analysis.
    Radiation oncology (London, England), 2020, May-06, Volume: 15, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Brain Neoplasms; Chemoradiotherapy; Female; Glioblastoma; Hippocampu

2020
Feasibility of hippocampus-sparing VMAT for newly diagnosed glioblastoma treated by chemoradiation: pattern of failure analysis.
    Radiation oncology (London, England), 2020, May-06, Volume: 15, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Brain Neoplasms; Chemoradiotherapy; Female; Glioblastoma; Hippocampu

2020
NF-кB inhibition by DHMEQ: in vitro antiproliferative effects on pilocytic astrocytoma and concise review of the current literature.
    Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 2020, Volume: 36, Issue:11

    Topics: Astrocytoma; Brain Neoplasms; Cell Proliferation; Child; Humans; NF-kappa B; Temozolomide

2020
NF-кB inhibition by DHMEQ: in vitro antiproliferative effects on pilocytic astrocytoma and concise review of the current literature.
    Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 2020, Volume: 36, Issue:11

    Topics: Astrocytoma; Brain Neoplasms; Cell Proliferation; Child; Humans; NF-kappa B; Temozolomide

2020
NF-кB inhibition by DHMEQ: in vitro antiproliferative effects on pilocytic astrocytoma and concise review of the current literature.
    Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 2020, Volume: 36, Issue:11

    Topics: Astrocytoma; Brain Neoplasms; Cell Proliferation; Child; Humans; NF-kappa B; Temozolomide

2020
Spinal metastasis of glioblastoma multiforme before gliosarcomatous transformation: a case report.
    BMC neurology, 2020, May-11, Volume: 20, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Brain; Brain Neoplasms; Craniotomy; Fatal Outcome; Female; Gliobl

2020
Spinal metastasis of glioblastoma multiforme before gliosarcomatous transformation: a case report.
    BMC neurology, 2020, May-11, Volume: 20, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Brain; Brain Neoplasms; Craniotomy; Fatal Outcome; Female; Gliobl

2020
Spinal metastasis of glioblastoma multiforme before gliosarcomatous transformation: a case report.
    BMC neurology, 2020, May-11, Volume: 20, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Brain; Brain Neoplasms; Craniotomy; Fatal Outcome; Female; Gliobl

2020
Development and in vivo evaluation of Irinotecan-loaded Drug Eluting Seeds (iDES) for the localised treatment of recurrent glioblastoma multiforme.
    Journal of controlled release : official journal of the Controlled Release Society, 2020, 08-10, Volume: 324

    Topics: Animals; Brain Neoplasms; Glioblastoma; Humans; Irinotecan; Mice; Pharmaceutical Preparations; Temoz

2020
Development and in vivo evaluation of Irinotecan-loaded Drug Eluting Seeds (iDES) for the localised treatment of recurrent glioblastoma multiforme.
    Journal of controlled release : official journal of the Controlled Release Society, 2020, 08-10, Volume: 324

    Topics: Animals; Brain Neoplasms; Glioblastoma; Humans; Irinotecan; Mice; Pharmaceutical Preparations; Temoz

2020
Development and in vivo evaluation of Irinotecan-loaded Drug Eluting Seeds (iDES) for the localised treatment of recurrent glioblastoma multiforme.
    Journal of controlled release : official journal of the Controlled Release Society, 2020, 08-10, Volume: 324

    Topics: Animals; Brain Neoplasms; Glioblastoma; Humans; Irinotecan; Mice; Pharmaceutical Preparations; Temoz

2020
Lumefantrine, an antimalarial drug, reverses radiation and temozolomide resistance in glioblastoma.
    Proceedings of the National Academy of Sciences of the United States of America, 2020, 06-02, Volume: 117, Issue:22

    Topics: Antimalarials; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Drug Resistance

2020
Lumefantrine, an antimalarial drug, reverses radiation and temozolomide resistance in glioblastoma.
    Proceedings of the National Academy of Sciences of the United States of America, 2020, 06-02, Volume: 117, Issue:22

    Topics: Antimalarials; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Drug Resistance

2020
Lumefantrine, an antimalarial drug, reverses radiation and temozolomide resistance in glioblastoma.
    Proceedings of the National Academy of Sciences of the United States of America, 2020, 06-02, Volume: 117, Issue:22

    Topics: Antimalarials; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Drug Resistance

2020
Prediction of Outcomes with a Computational Biology Model in Newly Diagnosed Glioblastoma Patients Treated with Radiation Therapy and Temozolomide.
    International journal of radiation oncology, biology, physics, 2020, 11-01, Volume: 108, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modalit

2020
Prediction of Outcomes with a Computational Biology Model in Newly Diagnosed Glioblastoma Patients Treated with Radiation Therapy and Temozolomide.
    International journal of radiation oncology, biology, physics, 2020, 11-01, Volume: 108, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modalit

2020
Prediction of Outcomes with a Computational Biology Model in Newly Diagnosed Glioblastoma Patients Treated with Radiation Therapy and Temozolomide.
    International journal of radiation oncology, biology, physics, 2020, 11-01, Volume: 108, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modalit

2020
CD73 as a target to improve temozolomide chemotherapy effect in glioblastoma preclinical model.
    Cancer chemotherapy and pharmacology, 2020, Volume: 85, Issue:6

    Topics: 5'-Nucleotidase; Animals; Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cell Prolif

2020
CD73 as a target to improve temozolomide chemotherapy effect in glioblastoma preclinical model.
    Cancer chemotherapy and pharmacology, 2020, Volume: 85, Issue:6

    Topics: 5'-Nucleotidase; Animals; Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cell Prolif

2020
CD73 as a target to improve temozolomide chemotherapy effect in glioblastoma preclinical model.
    Cancer chemotherapy and pharmacology, 2020, Volume: 85, Issue:6

    Topics: 5'-Nucleotidase; Animals; Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cell Prolif

2020
LncRNA SOX2OT promotes temozolomide resistance by elevating SOX2 expression via ALKBH5-mediated epigenetic regulation in glioblastoma.
    Cell death & disease, 2020, 05-21, Volume: 11, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation;

2020
LncRNA SOX2OT promotes temozolomide resistance by elevating SOX2 expression via ALKBH5-mediated epigenetic regulation in glioblastoma.
    Cell death & disease, 2020, 05-21, Volume: 11, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation;

2020
LncRNA SOX2OT promotes temozolomide resistance by elevating SOX2 expression via ALKBH5-mediated epigenetic regulation in glioblastoma.
    Cell death & disease, 2020, 05-21, Volume: 11, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation;

2020
Coumarins modulate the anti-glioma properties of temozolomide.
    European journal of pharmacology, 2020, Aug-15, Volume: 881

    Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Autophagy; Beclin-1; Brain Neoplasms; Cas

2020
Coumarins modulate the anti-glioma properties of temozolomide.
    European journal of pharmacology, 2020, Aug-15, Volume: 881

    Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Autophagy; Beclin-1; Brain Neoplasms; Cas

2020
Coumarins modulate the anti-glioma properties of temozolomide.
    European journal of pharmacology, 2020, Aug-15, Volume: 881

    Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Autophagy; Beclin-1; Brain Neoplasms; Cas

2020
New advances on the inhibition of Siwei Xiaoliuyin combined with Temozolomide in glioma based on the regulatory mechanism of miRNA21/221.
    International review of neurobiology, 2020, Volume: 151

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Disease Models, Animal; Drug Therapy, C

2020
New advances on the inhibition of Siwei Xiaoliuyin combined with Temozolomide in glioma based on the regulatory mechanism of miRNA21/221.
    International review of neurobiology, 2020, Volume: 151

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Disease Models, Animal; Drug Therapy, C

2020
New advances on the inhibition of Siwei Xiaoliuyin combined with Temozolomide in glioma based on the regulatory mechanism of miRNA21/221.
    International review of neurobiology, 2020, Volume: 151

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Disease Models, Animal; Drug Therapy, C

2020
Long term follow-up and outcomes in adult patients with thalamic gliomas.
    Clinical neurology and neurosurgery, 2020, Volume: 195

    Topics: Adult; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Female; Follow

2020
Long term follow-up and outcomes in adult patients with thalamic gliomas.
    Clinical neurology and neurosurgery, 2020, Volume: 195

    Topics: Adult; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Female; Follow

2020
Long term follow-up and outcomes in adult patients with thalamic gliomas.
    Clinical neurology and neurosurgery, 2020, Volume: 195

    Topics: Adult; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Female; Follow

2020
Temozolomide antagonizes oncolytic immunovirotherapy in glioblastoma.
    Journal for immunotherapy of cancer, 2020, Volume: 8, Issue:1

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Glioblastoma; Humans; Mice; Oncolytic V

2020
Temozolomide antagonizes oncolytic immunovirotherapy in glioblastoma.
    Journal for immunotherapy of cancer, 2020, Volume: 8, Issue:1

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Glioblastoma; Humans; Mice; Oncolytic V

2020
Temozolomide antagonizes oncolytic immunovirotherapy in glioblastoma.
    Journal for immunotherapy of cancer, 2020, Volume: 8, Issue:1

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Glioblastoma; Humans; Mice; Oncolytic V

2020
Newly diagnosed glioblastoma in the elderly: when is temozolomide alone enough?
    Neuro-oncology, 2020, 08-17, Volume: 22, Issue:8

    Topics: Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; DNA Methylation; DNA Modifica

2020
Newly diagnosed glioblastoma in the elderly: when is temozolomide alone enough?
    Neuro-oncology, 2020, 08-17, Volume: 22, Issue:8

    Topics: Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; DNA Methylation; DNA Modifica

2020
Newly diagnosed glioblastoma in the elderly: when is temozolomide alone enough?
    Neuro-oncology, 2020, 08-17, Volume: 22, Issue:8

    Topics: Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; DNA Methylation; DNA Modifica

2020
Extreme hypofractionation for newly diagnosed glioblastoma: rationale, dose, techniques, and outcomes.
    Neuro-oncology, 2020, 08-17, Volume: 22, Issue:8

    Topics: Brain Neoplasms; Glioblastoma; Humans; Radiation Dose Hypofractionation; Radiosurgery; Temozolomide

2020
Extreme hypofractionation for newly diagnosed glioblastoma: rationale, dose, techniques, and outcomes.
    Neuro-oncology, 2020, 08-17, Volume: 22, Issue:8

    Topics: Brain Neoplasms; Glioblastoma; Humans; Radiation Dose Hypofractionation; Radiosurgery; Temozolomide

2020
Extreme hypofractionation for newly diagnosed glioblastoma: rationale, dose, techniques, and outcomes.
    Neuro-oncology, 2020, 08-17, Volume: 22, Issue:8

    Topics: Brain Neoplasms; Glioblastoma; Humans; Radiation Dose Hypofractionation; Radiosurgery; Temozolomide

2020
The clinical characteristics and prognostic factors of multiple lesions in glioblastomas.
    Clinical neurology and neurosurgery, 2020, Volume: 195

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; DNA Modification

2020
The clinical characteristics and prognostic factors of multiple lesions in glioblastomas.
    Clinical neurology and neurosurgery, 2020, Volume: 195

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; DNA Modification

2020
The clinical characteristics and prognostic factors of multiple lesions in glioblastomas.
    Clinical neurology and neurosurgery, 2020, Volume: 195

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; DNA Modification

2020
Development of a human in vitro blood-brain tumor barrier model of diffuse intrinsic pontine glioma to better understand the chemoresistance.
    Fluids and barriers of the CNS, 2020, Jun-02, Volume: 17, Issue:1

    Topics: Antineoplastic Agents; Blood-Brain Barrier; Brain Neoplasms; Cells, Cultured; Diffuse Intrinsic Pont

2020
Development of a human in vitro blood-brain tumor barrier model of diffuse intrinsic pontine glioma to better understand the chemoresistance.
    Fluids and barriers of the CNS, 2020, Jun-02, Volume: 17, Issue:1

    Topics: Antineoplastic Agents; Blood-Brain Barrier; Brain Neoplasms; Cells, Cultured; Diffuse Intrinsic Pont

2020
Development of a human in vitro blood-brain tumor barrier model of diffuse intrinsic pontine glioma to better understand the chemoresistance.
    Fluids and barriers of the CNS, 2020, Jun-02, Volume: 17, Issue:1

    Topics: Antineoplastic Agents; Blood-Brain Barrier; Brain Neoplasms; Cells, Cultured; Diffuse Intrinsic Pont

2020
A Prospective Cohort Study of Neural Progenitor Cell-Sparing Radiation Therapy Plus Temozolomide for Newly Diagnosed Patients With Glioblastoma.
    Neurosurgery, 2020, 07-01, Volume: 87, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherap

2020
A Prospective Cohort Study of Neural Progenitor Cell-Sparing Radiation Therapy Plus Temozolomide for Newly Diagnosed Patients With Glioblastoma.
    Neurosurgery, 2020, 07-01, Volume: 87, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherap

2020
A Prospective Cohort Study of Neural Progenitor Cell-Sparing Radiation Therapy Plus Temozolomide for Newly Diagnosed Patients With Glioblastoma.
    Neurosurgery, 2020, 07-01, Volume: 87, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherap

2020
Multidimensional hydrogel models reveal endothelial network angiocrine signals increase glioblastoma cell number, invasion, and temozolomide resistance.
    Integrative biology : quantitative biosciences from nano to macro, 2020, 06-19, Volume: 12, Issue:6

    Topics: Biocompatible Materials; Brain Neoplasms; Cell Count; Cell Line, Tumor; Cell Movement; Cell Prolifer

2020
Multidimensional hydrogel models reveal endothelial network angiocrine signals increase glioblastoma cell number, invasion, and temozolomide resistance.
    Integrative biology : quantitative biosciences from nano to macro, 2020, 06-19, Volume: 12, Issue:6

    Topics: Biocompatible Materials; Brain Neoplasms; Cell Count; Cell Line, Tumor; Cell Movement; Cell Prolifer

2020
Multidimensional hydrogel models reveal endothelial network angiocrine signals increase glioblastoma cell number, invasion, and temozolomide resistance.
    Integrative biology : quantitative biosciences from nano to macro, 2020, 06-19, Volume: 12, Issue:6

    Topics: Biocompatible Materials; Brain Neoplasms; Cell Count; Cell Line, Tumor; Cell Movement; Cell Prolifer

2020
Noninvasive diffusion magnetic resonance imaging of brain tumour cell size for the early detection of therapeutic response.
    Scientific reports, 2020, 06-08, Volume: 10, Issue:1

    Topics: Animals; Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neoplasms; Cell Line, Tumor; Diffusio

2020
Noninvasive diffusion magnetic resonance imaging of brain tumour cell size for the early detection of therapeutic response.
    Scientific reports, 2020, 06-08, Volume: 10, Issue:1

    Topics: Animals; Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neoplasms; Cell Line, Tumor; Diffusio

2020
Noninvasive diffusion magnetic resonance imaging of brain tumour cell size for the early detection of therapeutic response.
    Scientific reports, 2020, 06-08, Volume: 10, Issue:1

    Topics: Animals; Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neoplasms; Cell Line, Tumor; Diffusio

2020
MicroRNA-128-3p Enhances the Chemosensitivity of Temozolomide in Glioblastoma by Targeting c-Met and EMT.
    Scientific reports, 2020, 06-11, Volume: 10, Issue:1

    Topics: Animals; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Drug Resistance, Neoplasm

2020
MicroRNA-128-3p Enhances the Chemosensitivity of Temozolomide in Glioblastoma by Targeting c-Met and EMT.
    Scientific reports, 2020, 06-11, Volume: 10, Issue:1

    Topics: Animals; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Drug Resistance, Neoplasm

2020
MicroRNA-128-3p Enhances the Chemosensitivity of Temozolomide in Glioblastoma by Targeting c-Met and EMT.
    Scientific reports, 2020, 06-11, Volume: 10, Issue:1

    Topics: Animals; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Drug Resistance, Neoplasm

2020
Observation versus radiotherapy with or without temozolomide in postoperative WHO grade II high-risk low-grade glioma: a retrospective cohort study.
    Neurosurgical review, 2021, Volume: 44, Issue:3

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cohort Studies; Female; Follow-Up S

2021
Observation versus radiotherapy with or without temozolomide in postoperative WHO grade II high-risk low-grade glioma: a retrospective cohort study.
    Neurosurgical review, 2021, Volume: 44, Issue:3

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cohort Studies; Female; Follow-Up S

2021
Observation versus radiotherapy with or without temozolomide in postoperative WHO grade II high-risk low-grade glioma: a retrospective cohort study.
    Neurosurgical review, 2021, Volume: 44, Issue:3

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cohort Studies; Female; Follow-Up S

2021
LncRNA MIR155HG Promotes Temozolomide Resistance by Activating the Wnt/β-Catenin Pathway Via Binding to PTBP1 in Glioma.
    Cellular and molecular neurobiology, 2021, Volume: 41, Issue:6

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Drug Resistance, Neop

2021
LncRNA MIR155HG Promotes Temozolomide Resistance by Activating the Wnt/β-Catenin Pathway Via Binding to PTBP1 in Glioma.
    Cellular and molecular neurobiology, 2021, Volume: 41, Issue:6

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Drug Resistance, Neop

2021
LncRNA MIR155HG Promotes Temozolomide Resistance by Activating the Wnt/β-Catenin Pathway Via Binding to PTBP1 in Glioma.
    Cellular and molecular neurobiology, 2021, Volume: 41, Issue:6

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Drug Resistance, Neop

2021
Brain metastases from esophageal cancer: A case report.
    Medicine, 2020, Jun-12, Volume: 99, Issue:24

    Topics: Administration, Oral; Aftercare; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined

2020
Brain metastases from esophageal cancer: A case report.
    Medicine, 2020, Jun-12, Volume: 99, Issue:24

    Topics: Administration, Oral; Aftercare; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined

2020
Brain metastases from esophageal cancer: A case report.
    Medicine, 2020, Jun-12, Volume: 99, Issue:24

    Topics: Administration, Oral; Aftercare; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined

2020
A contemporary perspective on the diagnosis and treatment of diffuse gliomas in adults.
    Swiss medical weekly, 2020, Jun-01, Volume: 150

    Topics: Adult; Brain Neoplasms; Glioblastoma; Glioma; Humans; Isocitrate Dehydrogenase; Mutation; Neoplasm R

2020
A contemporary perspective on the diagnosis and treatment of diffuse gliomas in adults.
    Swiss medical weekly, 2020, Jun-01, Volume: 150

    Topics: Adult; Brain Neoplasms; Glioblastoma; Glioma; Humans; Isocitrate Dehydrogenase; Mutation; Neoplasm R

2020
A contemporary perspective on the diagnosis and treatment of diffuse gliomas in adults.
    Swiss medical weekly, 2020, Jun-01, Volume: 150

    Topics: Adult; Brain Neoplasms; Glioblastoma; Glioma; Humans; Isocitrate Dehydrogenase; Mutation; Neoplasm R

2020
The combined effect of neutron irradiation and temozolomide on glioblastoma cell lines with different MGMT and P53 status.
    Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine, 2020, Volume: 163

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Combined Modality Therapy; DNA

2020
The combined effect of neutron irradiation and temozolomide on glioblastoma cell lines with different MGMT and P53 status.
    Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine, 2020, Volume: 163

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Combined Modality Therapy; DNA

2020
The combined effect of neutron irradiation and temozolomide on glioblastoma cell lines with different MGMT and P53 status.
    Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine, 2020, Volume: 163

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Combined Modality Therapy; DNA

2020
Prognostic Value of Pretreatment Systemic Immune-Inflammation Index in Glioblastoma Multiforme Patients Undergoing Postneurosurgical Radiotherapy Plus Concurrent and Adjuvant Temozolomide.
    Mediators of inflammation, 2020, Volume: 2020

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Blood Platelets; Brain Neoplasms; Chemoradiotherapy; Com

2020
Prognostic Value of Pretreatment Systemic Immune-Inflammation Index in Glioblastoma Multiforme Patients Undergoing Postneurosurgical Radiotherapy Plus Concurrent and Adjuvant Temozolomide.
    Mediators of inflammation, 2020, Volume: 2020

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Blood Platelets; Brain Neoplasms; Chemoradiotherapy; Com

2020
Prognostic Value of Pretreatment Systemic Immune-Inflammation Index in Glioblastoma Multiforme Patients Undergoing Postneurosurgical Radiotherapy Plus Concurrent and Adjuvant Temozolomide.
    Mediators of inflammation, 2020, Volume: 2020

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Blood Platelets; Brain Neoplasms; Chemoradiotherapy; Com

2020
Central diabetes insipidus: A rare unreported side effect of temozolomide in pediatrics.
    Pediatric blood & cancer, 2020, Volume: 67, Issue:12

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Child; Diabetes Insipidus, Neurogenic; Humans; M

2020
Central diabetes insipidus: A rare unreported side effect of temozolomide in pediatrics.
    Pediatric blood & cancer, 2020, Volume: 67, Issue:12

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Child; Diabetes Insipidus, Neurogenic; Humans; M

2020
Central diabetes insipidus: A rare unreported side effect of temozolomide in pediatrics.
    Pediatric blood & cancer, 2020, Volume: 67, Issue:12

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Child; Diabetes Insipidus, Neurogenic; Humans; M

2020
Nuclear Respiratory Factor 1 (NRF1) Transcriptional Activity-Driven Gene Signature Association with Severity of Astrocytoma and Poor Prognosis of Glioblastoma.
    Molecular neurobiology, 2020, Volume: 57, Issue:9

    Topics: Adult; Apoptosis; Astrocytoma; Biomarkers, Tumor; Brain Neoplasms; Cell Cycle; Cell Differentiation;

2020
Nuclear Respiratory Factor 1 (NRF1) Transcriptional Activity-Driven Gene Signature Association with Severity of Astrocytoma and Poor Prognosis of Glioblastoma.
    Molecular neurobiology, 2020, Volume: 57, Issue:9

    Topics: Adult; Apoptosis; Astrocytoma; Biomarkers, Tumor; Brain Neoplasms; Cell Cycle; Cell Differentiation;

2020
Nuclear Respiratory Factor 1 (NRF1) Transcriptional Activity-Driven Gene Signature Association with Severity of Astrocytoma and Poor Prognosis of Glioblastoma.
    Molecular neurobiology, 2020, Volume: 57, Issue:9

    Topics: Adult; Apoptosis; Astrocytoma; Biomarkers, Tumor; Brain Neoplasms; Cell Cycle; Cell Differentiation;

2020
Xihuang pill potentiates the anti-tumor effects of temozolomide in glioblastoma xenografts through the Akt/mTOR-dependent pathway.
    Journal of ethnopharmacology, 2020, Oct-28, Volume: 261

    Topics: Animals; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Apoptosi

2020
Xihuang pill potentiates the anti-tumor effects of temozolomide in glioblastoma xenografts through the Akt/mTOR-dependent pathway.
    Journal of ethnopharmacology, 2020, Oct-28, Volume: 261

    Topics: Animals; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Apoptosi

2020
Xihuang pill potentiates the anti-tumor effects of temozolomide in glioblastoma xenografts through the Akt/mTOR-dependent pathway.
    Journal of ethnopharmacology, 2020, Oct-28, Volume: 261

    Topics: Animals; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Apoptosi

2020
A co-formulation of interferons type I and II enhances temozolomide response in glioblastoma with unmethylated MGMT promoter status.
    Molecular biology reports, 2020, Volume: 47, Issue:7

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; DNA Methyl

2020
A co-formulation of interferons type I and II enhances temozolomide response in glioblastoma with unmethylated MGMT promoter status.
    Molecular biology reports, 2020, Volume: 47, Issue:7

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; DNA Methyl

2020
A co-formulation of interferons type I and II enhances temozolomide response in glioblastoma with unmethylated MGMT promoter status.
    Molecular biology reports, 2020, Volume: 47, Issue:7

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; DNA Methyl

2020
Celecoxib substituted biotinylated poly(amidoamine) G3 dendrimer as potential treatment for temozolomide resistant glioma therapy and anti-nematode agent.
    European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2020, Sep-01, Volume: 152

    Topics: Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Celecoxib; Cell Line, Tumor; Dendrime

2020
Celecoxib substituted biotinylated poly(amidoamine) G3 dendrimer as potential treatment for temozolomide resistant glioma therapy and anti-nematode agent.
    European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2020, Sep-01, Volume: 152

    Topics: Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Celecoxib; Cell Line, Tumor; Dendrime

2020
Celecoxib substituted biotinylated poly(amidoamine) G3 dendrimer as potential treatment for temozolomide resistant glioma therapy and anti-nematode agent.
    European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2020, Sep-01, Volume: 152

    Topics: Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Celecoxib; Cell Line, Tumor; Dendrime

2020
Conventional Treatment of Glioblastoma Reveals Persistent CD44
    Molecular neurobiology, 2020, Volume: 57, Issue:9

    Topics: Animals; Brain Neoplasms; Cell Line, Tumor; Disease Progression; Glioblastoma; Humans; Hyaluronan Re

2020
Conventional Treatment of Glioblastoma Reveals Persistent CD44
    Molecular neurobiology, 2020, Volume: 57, Issue:9

    Topics: Animals; Brain Neoplasms; Cell Line, Tumor; Disease Progression; Glioblastoma; Humans; Hyaluronan Re

2020
Conventional Treatment of Glioblastoma Reveals Persistent CD44
    Molecular neurobiology, 2020, Volume: 57, Issue:9

    Topics: Animals; Brain Neoplasms; Cell Line, Tumor; Disease Progression; Glioblastoma; Humans; Hyaluronan Re

2020
A composite of graphene oxide and iron oxide nanoparticles for targeted drug delivery of temozolomide.
    Die Pharmazie, 2020, 07-01, Volume: 75, Issue:7

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; D

2020
A composite of graphene oxide and iron oxide nanoparticles for targeted drug delivery of temozolomide.
    Die Pharmazie, 2020, 07-01, Volume: 75, Issue:7

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; D

2020
A composite of graphene oxide and iron oxide nanoparticles for targeted drug delivery of temozolomide.
    Die Pharmazie, 2020, 07-01, Volume: 75, Issue:7

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; D

2020
Single-cell RNA-seq reveals that glioblastoma recapitulates a normal neurodevelopmental hierarchy.
    Nature communications, 2020, 07-08, Volume: 11, Issue:1

    Topics: Adult; Animals; Antineoplastic Agents, Alkylating; Brain; Brain Neoplasms; Cell Survival; Cells, Cul

2020
Single-cell RNA-seq reveals that glioblastoma recapitulates a normal neurodevelopmental hierarchy.
    Nature communications, 2020, 07-08, Volume: 11, Issue:1

    Topics: Adult; Animals; Antineoplastic Agents, Alkylating; Brain; Brain Neoplasms; Cell Survival; Cells, Cul

2020
Single-cell RNA-seq reveals that glioblastoma recapitulates a normal neurodevelopmental hierarchy.
    Nature communications, 2020, 07-08, Volume: 11, Issue:1

    Topics: Adult; Animals; Antineoplastic Agents, Alkylating; Brain; Brain Neoplasms; Cell Survival; Cells, Cul

2020
Temozolomide-Doxorubicin Conjugate as a Double Intercalating Agent and Delivery by Apoferritin for Glioblastoma Chemotherapy.
    ACS applied materials & interfaces, 2020, Aug-05, Volume: 12, Issue:31

    Topics: Antineoplastic Agents; Apoferritins; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Cell Sur

2020
Temozolomide-Doxorubicin Conjugate as a Double Intercalating Agent and Delivery by Apoferritin for Glioblastoma Chemotherapy.
    ACS applied materials & interfaces, 2020, Aug-05, Volume: 12, Issue:31

    Topics: Antineoplastic Agents; Apoferritins; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Cell Sur

2020
Temozolomide-Doxorubicin Conjugate as a Double Intercalating Agent and Delivery by Apoferritin for Glioblastoma Chemotherapy.
    ACS applied materials & interfaces, 2020, Aug-05, Volume: 12, Issue:31

    Topics: Antineoplastic Agents; Apoferritins; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Cell Sur

2020
Glioblastoma and bevacizumab in elderly patients: Monocentric study.
    Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners, 2021, Volume: 27, Issue:4

    Topics: Adult; Age Factors; Aged; Antineoplastic Agents, Alkylating; Bevacizumab; Brain Neoplasms; Female; G

2021
Glioblastoma and bevacizumab in elderly patients: Monocentric study.
    Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners, 2021, Volume: 27, Issue:4

    Topics: Adult; Age Factors; Aged; Antineoplastic Agents, Alkylating; Bevacizumab; Brain Neoplasms; Female; G

2021
Glioblastoma and bevacizumab in elderly patients: Monocentric study.
    Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners, 2021, Volume: 27, Issue:4

    Topics: Adult; Age Factors; Aged; Antineoplastic Agents, Alkylating; Bevacizumab; Brain Neoplasms; Female; G

2021
Effect of valproic acid on overall survival in patients with high-grade gliomas undergoing temozolomide: A nationwide population-based cohort study in Taiwan.
    Medicine, 2020, Jul-10, Volume: 99, Issue:28

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Enzyme Inhibitors; Fema

2020
Effect of valproic acid on overall survival in patients with high-grade gliomas undergoing temozolomide: A nationwide population-based cohort study in Taiwan.
    Medicine, 2020, Jul-10, Volume: 99, Issue:28

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Enzyme Inhibitors; Fema

2020
Effect of valproic acid on overall survival in patients with high-grade gliomas undergoing temozolomide: A nationwide population-based cohort study in Taiwan.
    Medicine, 2020, Jul-10, Volume: 99, Issue:28

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Enzyme Inhibitors; Fema

2020
Combination Therapy with Nanomicellar-Curcumin and Temozolomide for In Vitro Therapy of Glioblastoma Multiforme via Wnt Signaling Pathways.
    Journal of molecular neuroscience : MN, 2020, Volume: 70, Issue:10

    Topics: Antineoplastic Agents; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cell Movement; Cell Proliferati

2020
Combination Therapy with Nanomicellar-Curcumin and Temozolomide for In Vitro Therapy of Glioblastoma Multiforme via Wnt Signaling Pathways.
    Journal of molecular neuroscience : MN, 2020, Volume: 70, Issue:10

    Topics: Antineoplastic Agents; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cell Movement; Cell Proliferati

2020
Combination Therapy with Nanomicellar-Curcumin and Temozolomide for In Vitro Therapy of Glioblastoma Multiforme via Wnt Signaling Pathways.
    Journal of molecular neuroscience : MN, 2020, Volume: 70, Issue:10

    Topics: Antineoplastic Agents; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cell Movement; Cell Proliferati

2020
FTO Inhibition Enhances the Antitumor Effect of Temozolomide by Targeting MYC-miR-155/23a Cluster-MXI1 Feedback Circuit in Glioma.
    Cancer research, 2020, 09-15, Volume: 80, Issue:18

    Topics: Alpha-Ketoglutarate-Dependent Dioxygenase FTO; Animals; Antineoplastic Agents, Alkylating; Basic Hel

2020
FTO Inhibition Enhances the Antitumor Effect of Temozolomide by Targeting MYC-miR-155/23a Cluster-MXI1 Feedback Circuit in Glioma.
    Cancer research, 2020, 09-15, Volume: 80, Issue:18

    Topics: Alpha-Ketoglutarate-Dependent Dioxygenase FTO; Animals; Antineoplastic Agents, Alkylating; Basic Hel

2020
FTO Inhibition Enhances the Antitumor Effect of Temozolomide by Targeting MYC-miR-155/23a Cluster-MXI1 Feedback Circuit in Glioma.
    Cancer research, 2020, 09-15, Volume: 80, Issue:18

    Topics: Alpha-Ketoglutarate-Dependent Dioxygenase FTO; Animals; Antineoplastic Agents, Alkylating; Basic Hel

2020
Suppressing Dazl modulates tumorigenicity and stemness in human glioblastoma cells.
    BMC cancer, 2020, Jul-18, Volume: 20, Issue:1

    Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Carcinogenesis; Cell Line, Tumor; Cell Movement; Ce

2020
Suppressing Dazl modulates tumorigenicity and stemness in human glioblastoma cells.
    BMC cancer, 2020, Jul-18, Volume: 20, Issue:1

    Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Carcinogenesis; Cell Line, Tumor; Cell Movement; Ce

2020
Suppressing Dazl modulates tumorigenicity and stemness in human glioblastoma cells.
    BMC cancer, 2020, Jul-18, Volume: 20, Issue:1

    Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Carcinogenesis; Cell Line, Tumor; Cell Movement; Ce

2020
HIF1α and p53 Regulated MED30, a Mediator Complex Subunit, is Involved in Regulation of Glioblastoma Pathogenesis and Temozolomide Resistance.
    Cellular and molecular neurobiology, 2021, Volume: 41, Issue:7

    Topics: Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Gene Expression Regulation, Neoplastic; Gliob

2021
HIF1α and p53 Regulated MED30, a Mediator Complex Subunit, is Involved in Regulation of Glioblastoma Pathogenesis and Temozolomide Resistance.
    Cellular and molecular neurobiology, 2021, Volume: 41, Issue:7

    Topics: Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Gene Expression Regulation, Neoplastic; Gliob

2021
HIF1α and p53 Regulated MED30, a Mediator Complex Subunit, is Involved in Regulation of Glioblastoma Pathogenesis and Temozolomide Resistance.
    Cellular and molecular neurobiology, 2021, Volume: 41, Issue:7

    Topics: Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Gene Expression Regulation, Neoplastic; Gliob

2021
MGMT-inhibitor in combination with TGF-βRI inhibitor or CDK 4/6 inhibitor increases temozolomide sensitivity in temozolomide-resistant glioblastoma cells.
    Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico, 2021, Volume: 23, Issue:3

    Topics: Aminopyridines; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; A

2021
MGMT-inhibitor in combination with TGF-βRI inhibitor or CDK 4/6 inhibitor increases temozolomide sensitivity in temozolomide-resistant glioblastoma cells.
    Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico, 2021, Volume: 23, Issue:3

    Topics: Aminopyridines; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; A

2021
MGMT-inhibitor in combination with TGF-βRI inhibitor or CDK 4/6 inhibitor increases temozolomide sensitivity in temozolomide-resistant glioblastoma cells.
    Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico, 2021, Volume: 23, Issue:3

    Topics: Aminopyridines; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; A

2021
Vascularized Temporoparietal Fascial Flap: A Novel Surgical Technique to Bypass the Blood-Brain Barrier in Glioblastoma.
    World neurosurgery, 2020, Volume: 143

    Topics: Antineoplastic Agents, Alkylating; Blood-Brain Barrier; Brain Neoplasms; Chemoradiotherapy, Adjuvant

2020
Vascularized Temporoparietal Fascial Flap: A Novel Surgical Technique to Bypass the Blood-Brain Barrier in Glioblastoma.
    World neurosurgery, 2020, Volume: 143

    Topics: Antineoplastic Agents, Alkylating; Blood-Brain Barrier; Brain Neoplasms; Chemoradiotherapy, Adjuvant

2020
Vascularized Temporoparietal Fascial Flap: A Novel Surgical Technique to Bypass the Blood-Brain Barrier in Glioblastoma.
    World neurosurgery, 2020, Volume: 143

    Topics: Antineoplastic Agents, Alkylating; Blood-Brain Barrier; Brain Neoplasms; Chemoradiotherapy, Adjuvant

2020
Combined effects of niclosamide and temozolomide against human glioblastoma tumorspheres.
    Journal of cancer research and clinical oncology, 2020, Volume: 146, Issue:11

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Cell Line, Tumor; Cell Sur

2020
Combined effects of niclosamide and temozolomide against human glioblastoma tumorspheres.
    Journal of cancer research and clinical oncology, 2020, Volume: 146, Issue:11

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Cell Line, Tumor; Cell Sur

2020
Combined effects of niclosamide and temozolomide against human glioblastoma tumorspheres.
    Journal of cancer research and clinical oncology, 2020, Volume: 146, Issue:11

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Cell Line, Tumor; Cell Sur

2020
Phospholipase D1 inhibition sensitizes glioblastoma to temozolomide and suppresses its tumorigenicity.
    The Journal of pathology, 2020, Volume: 252, Issue:3

    Topics: Animals; Antineoplastic Agents, Alkylating; Biomarkers, Tumor; Brain Neoplasms; Carcinogenesis; Cell

2020
Phospholipase D1 inhibition sensitizes glioblastoma to temozolomide and suppresses its tumorigenicity.
    The Journal of pathology, 2020, Volume: 252, Issue:3

    Topics: Animals; Antineoplastic Agents, Alkylating; Biomarkers, Tumor; Brain Neoplasms; Carcinogenesis; Cell

2020
Phospholipase D1 inhibition sensitizes glioblastoma to temozolomide and suppresses its tumorigenicity.
    The Journal of pathology, 2020, Volume: 252, Issue:3

    Topics: Animals; Antineoplastic Agents, Alkylating; Biomarkers, Tumor; Brain Neoplasms; Carcinogenesis; Cell

2020
ABCC8 mRNA expression is an independent prognostic factor for glioma and can predict chemosensitivity.
    Scientific reports, 2020, 07-29, Volume: 10, Issue:1

    Topics: Adult; Biomarkers, Tumor; Brain Neoplasms; Chromosome Deletion; Female; Gene Expression Regulation,

2020
ABCC8 mRNA expression is an independent prognostic factor for glioma and can predict chemosensitivity.
    Scientific reports, 2020, 07-29, Volume: 10, Issue:1

    Topics: Adult; Biomarkers, Tumor; Brain Neoplasms; Chromosome Deletion; Female; Gene Expression Regulation,

2020
ABCC8 mRNA expression is an independent prognostic factor for glioma and can predict chemosensitivity.
    Scientific reports, 2020, 07-29, Volume: 10, Issue:1

    Topics: Adult; Biomarkers, Tumor; Brain Neoplasms; Chromosome Deletion; Female; Gene Expression Regulation,

2020
Influence of glioblastoma contact with the subventricular zone on survival and recurrence patterns.
    Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico, 2021, Volume: 23, Issue:3

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Confidence Intervals; Female;

2021
Influence of glioblastoma contact with the subventricular zone on survival and recurrence patterns.
    Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico, 2021, Volume: 23, Issue:3

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Confidence Intervals; Female;

2021
Influence of glioblastoma contact with the subventricular zone on survival and recurrence patterns.
    Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico, 2021, Volume: 23, Issue:3

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Confidence Intervals; Female;

2021
Age-stratified clinical performance and survival of patients with IDH-wildtype glioblastoma homogeneously treated by radiotherapy with concomitant and maintenance temozolomide.
    Journal of cancer research and clinical oncology, 2021, Volume: 147, Issue:1

    Topics: Adult; Age Factors; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Biomarkers, Tumor; B

2021
Age-stratified clinical performance and survival of patients with IDH-wildtype glioblastoma homogeneously treated by radiotherapy with concomitant and maintenance temozolomide.
    Journal of cancer research and clinical oncology, 2021, Volume: 147, Issue:1

    Topics: Adult; Age Factors; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Biomarkers, Tumor; B

2021
Age-stratified clinical performance and survival of patients with IDH-wildtype glioblastoma homogeneously treated by radiotherapy with concomitant and maintenance temozolomide.
    Journal of cancer research and clinical oncology, 2021, Volume: 147, Issue:1

    Topics: Adult; Age Factors; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Biomarkers, Tumor; B

2021
MGMT genomic rearrangements contribute to chemotherapy resistance in gliomas.
    Nature communications, 2020, 08-04, Volume: 11, Issue:1

    Topics: Adolescent; Adult; Aged; Animals; Brain Neoplasms; Cell Line, Tumor; DNA Adducts; DNA Methylation; D

2020
MGMT genomic rearrangements contribute to chemotherapy resistance in gliomas.
    Nature communications, 2020, 08-04, Volume: 11, Issue:1

    Topics: Adolescent; Adult; Aged; Animals; Brain Neoplasms; Cell Line, Tumor; DNA Adducts; DNA Methylation; D

2020
MGMT genomic rearrangements contribute to chemotherapy resistance in gliomas.
    Nature communications, 2020, 08-04, Volume: 11, Issue:1

    Topics: Adolescent; Adult; Aged; Animals; Brain Neoplasms; Cell Line, Tumor; DNA Adducts; DNA Methylation; D

2020
NF-κB inhibitor with Temozolomide results in significant apoptosis in glioblastoma via the NF-κB(p65) and actin cytoskeleton regulatory pathways.
    Scientific reports, 2020, 08-07, Volume: 10, Issue:1

    Topics: Actin Cytoskeleton; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Enzyme-Linked Immunosorbent Assay;

2020
NF-κB inhibitor with Temozolomide results in significant apoptosis in glioblastoma via the NF-κB(p65) and actin cytoskeleton regulatory pathways.
    Scientific reports, 2020, 08-07, Volume: 10, Issue:1

    Topics: Actin Cytoskeleton; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Enzyme-Linked Immunosorbent Assay;

2020
NF-κB inhibitor with Temozolomide results in significant apoptosis in glioblastoma via the NF-κB(p65) and actin cytoskeleton regulatory pathways.
    Scientific reports, 2020, 08-07, Volume: 10, Issue:1

    Topics: Actin Cytoskeleton; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Enzyme-Linked Immunosorbent Assay;

2020
Temozolomide desensitization followed by metronomic dosing in patients with hypersensitivity.
    Cancer chemotherapy and pharmacology, 2020, Volume: 86, Issue:3

    Topics: Administration, Metronomic; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoth

2020
Temozolomide desensitization followed by metronomic dosing in patients with hypersensitivity.
    Cancer chemotherapy and pharmacology, 2020, Volume: 86, Issue:3

    Topics: Administration, Metronomic; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoth

2020
Temozolomide desensitization followed by metronomic dosing in patients with hypersensitivity.
    Cancer chemotherapy and pharmacology, 2020, Volume: 86, Issue:3

    Topics: Administration, Metronomic; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoth

2020
Targeting BC200/miR218-5p Signaling Axis for Overcoming Temozolomide Resistance and Suppressing Glioma Stemness.
    Cells, 2020, 08-08, Volume: 9, Issue:8

    Topics: Aged; Animals; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Drug Resistance, Neoplasm; Fem

2020
Targeting BC200/miR218-5p Signaling Axis for Overcoming Temozolomide Resistance and Suppressing Glioma Stemness.
    Cells, 2020, 08-08, Volume: 9, Issue:8

    Topics: Aged; Animals; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Drug Resistance, Neoplasm; Fem

2020
Targeting BC200/miR218-5p Signaling Axis for Overcoming Temozolomide Resistance and Suppressing Glioma Stemness.
    Cells, 2020, 08-08, Volume: 9, Issue:8

    Topics: Aged; Animals; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Drug Resistance, Neoplasm; Fem

2020
Comparative molecular analysis of primary and recurrent oligodendroglioma that acquired imbalanced 1p/19q codeletion and TP53 mutation: a case report.
    Acta neurochirurgica, 2020, Volume: 162, Issue:12

    Topics: Adult; Antineoplastic Agents, Alkylating; Brain Neoplasms; Female; Humans; Isocitrate Dehydrogenase;

2020
Comparative molecular analysis of primary and recurrent oligodendroglioma that acquired imbalanced 1p/19q codeletion and TP53 mutation: a case report.
    Acta neurochirurgica, 2020, Volume: 162, Issue:12

    Topics: Adult; Antineoplastic Agents, Alkylating; Brain Neoplasms; Female; Humans; Isocitrate Dehydrogenase;

2020
Comparative molecular analysis of primary and recurrent oligodendroglioma that acquired imbalanced 1p/19q codeletion and TP53 mutation: a case report.
    Acta neurochirurgica, 2020, Volume: 162, Issue:12

    Topics: Adult; Antineoplastic Agents, Alkylating; Brain Neoplasms; Female; Humans; Isocitrate Dehydrogenase;

2020
Brachyury Is Associated with Glioma Differentiation and Response to Temozolomide.
    Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics, 2020, Volume: 17, Issue:4

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Differentiation; Cell Line, Tumor; Cell Mov

2020
Brachyury Is Associated with Glioma Differentiation and Response to Temozolomide.
    Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics, 2020, Volume: 17, Issue:4

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Differentiation; Cell Line, Tumor; Cell Mov

2020
Brachyury Is Associated with Glioma Differentiation and Response to Temozolomide.
    Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics, 2020, Volume: 17, Issue:4

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Differentiation; Cell Line, Tumor; Cell Mov

2020
PAMs inhibits monoamine oxidase a activity and reduces glioma tumor growth, a potential adjuvant treatment for glioma.
    BMC complementary medicine and therapies, 2020, Aug-15, Volume: 20, Issue:1

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Disease Models, Anima

2020
PAMs inhibits monoamine oxidase a activity and reduces glioma tumor growth, a potential adjuvant treatment for glioma.
    BMC complementary medicine and therapies, 2020, Aug-15, Volume: 20, Issue:1

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Disease Models, Anima

2020
PAMs inhibits monoamine oxidase a activity and reduces glioma tumor growth, a potential adjuvant treatment for glioma.
    BMC complementary medicine and therapies, 2020, Aug-15, Volume: 20, Issue:1

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Disease Models, Anima

2020
The different role of YKL-40 in glioblastoma is a function of MGMT promoter methylation status.
    Cell death & disease, 2020, 08-21, Volume: 11, Issue:8

    Topics: Adult; Brain Neoplasms; Chitinase-3-Like Protein 1; DNA Methylation; DNA Modification Methylases; DN

2020
The different role of YKL-40 in glioblastoma is a function of MGMT promoter methylation status.
    Cell death & disease, 2020, 08-21, Volume: 11, Issue:8

    Topics: Adult; Brain Neoplasms; Chitinase-3-Like Protein 1; DNA Methylation; DNA Modification Methylases; DN

2020
The different role of YKL-40 in glioblastoma is a function of MGMT promoter methylation status.
    Cell death & disease, 2020, 08-21, Volume: 11, Issue:8

    Topics: Adult; Brain Neoplasms; Chitinase-3-Like Protein 1; DNA Methylation; DNA Modification Methylases; DN

2020
Enhancement of glioblastoma multiforme therapy through a novel Quercetin-Losartan hybrid.
    Free radical biology & medicine, 2020, 11-20, Volume: 160

    Topics: Brain Neoplasms; Cell Line, Tumor; Glioblastoma; Humans; Losartan; Quercetin; Temozolomide

2020
Enhancement of glioblastoma multiforme therapy through a novel Quercetin-Losartan hybrid.
    Free radical biology & medicine, 2020, 11-20, Volume: 160

    Topics: Brain Neoplasms; Cell Line, Tumor; Glioblastoma; Humans; Losartan; Quercetin; Temozolomide

2020
Enhancement of glioblastoma multiforme therapy through a novel Quercetin-Losartan hybrid.
    Free radical biology & medicine, 2020, 11-20, Volume: 160

    Topics: Brain Neoplasms; Cell Line, Tumor; Glioblastoma; Humans; Losartan; Quercetin; Temozolomide

2020
Gradient hydrogels for screening stiffness effects on patient-derived glioblastoma xenograft cellfates in 3D.
    Journal of biomedical materials research. Part A, 2021, Volume: 109, Issue:6

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Disease Pr

2021
Gradient hydrogels for screening stiffness effects on patient-derived glioblastoma xenograft cellfates in 3D.
    Journal of biomedical materials research. Part A, 2021, Volume: 109, Issue:6

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Disease Pr

2021
Gradient hydrogels for screening stiffness effects on patient-derived glioblastoma xenograft cellfates in 3D.
    Journal of biomedical materials research. Part A, 2021, Volume: 109, Issue:6

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Disease Pr

2021
Preconditioning with INC280 and LDK378 drugs sensitizes MGMT-unmethylated glioblastoma to temozolomide: Pre-clinical assessment.
    Journal of the neurological sciences, 2020, Nov-15, Volume: 418

    Topics: Antineoplastic Agents, Alkylating; Benzamides; Brain Neoplasms; Cell Line, Tumor; DNA Modification M

2020
Preconditioning with INC280 and LDK378 drugs sensitizes MGMT-unmethylated glioblastoma to temozolomide: Pre-clinical assessment.
    Journal of the neurological sciences, 2020, Nov-15, Volume: 418

    Topics: Antineoplastic Agents, Alkylating; Benzamides; Brain Neoplasms; Cell Line, Tumor; DNA Modification M

2020
Preconditioning with INC280 and LDK378 drugs sensitizes MGMT-unmethylated glioblastoma to temozolomide: Pre-clinical assessment.
    Journal of the neurological sciences, 2020, Nov-15, Volume: 418

    Topics: Antineoplastic Agents, Alkylating; Benzamides; Brain Neoplasms; Cell Line, Tumor; DNA Modification M

2020
Developing a clinically relevant radiosensitizer for temozolomide-resistant gliomas.
    PloS one, 2020, Volume: 15, Issue:9

    Topics: Animals; Blood-Brain Barrier; Brain; Brain Neoplasms; Cell Line, Tumor; Cell Survival; Dacarbazine;

2020
Developing a clinically relevant radiosensitizer for temozolomide-resistant gliomas.
    PloS one, 2020, Volume: 15, Issue:9

    Topics: Animals; Blood-Brain Barrier; Brain; Brain Neoplasms; Cell Line, Tumor; Cell Survival; Dacarbazine;

2020
Developing a clinically relevant radiosensitizer for temozolomide-resistant gliomas.
    PloS one, 2020, Volume: 15, Issue:9

    Topics: Animals; Blood-Brain Barrier; Brain; Brain Neoplasms; Cell Line, Tumor; Cell Survival; Dacarbazine;

2020
Anti-PD-1, anti-VEGF, and temozolomide therapy in a patient with recurrent glioblastoma: a case report.
    The Journal of international medical research, 2020, Volume: 48, Issue:9

    Topics: Adult; Angiogenesis Inhibitors; Bevacizumab; Brain Neoplasms; Female; Glioblastoma; Humans; Neoplasm

2020
Anti-PD-1, anti-VEGF, and temozolomide therapy in a patient with recurrent glioblastoma: a case report.
    The Journal of international medical research, 2020, Volume: 48, Issue:9

    Topics: Adult; Angiogenesis Inhibitors; Bevacizumab; Brain Neoplasms; Female; Glioblastoma; Humans; Neoplasm

2020
Anti-PD-1, anti-VEGF, and temozolomide therapy in a patient with recurrent glioblastoma: a case report.
    The Journal of international medical research, 2020, Volume: 48, Issue:9

    Topics: Adult; Angiogenesis Inhibitors; Bevacizumab; Brain Neoplasms; Female; Glioblastoma; Humans; Neoplasm

2020
An interview with Buddy Ratner.
    Therapeutic delivery, 2020, Volume: 11, Issue:10

    Topics: Brain Neoplasms; Glioblastoma; Humans; Polyesters; Temozolomide

2020
An interview with Buddy Ratner.
    Therapeutic delivery, 2020, Volume: 11, Issue:10

    Topics: Brain Neoplasms; Glioblastoma; Humans; Polyesters; Temozolomide

2020
An interview with Buddy Ratner.
    Therapeutic delivery, 2020, Volume: 11, Issue:10

    Topics: Brain Neoplasms; Glioblastoma; Humans; Polyesters; Temozolomide

2020
PARP‑1 inhibition sensitizes temozolomide‑treated glioblastoma cell lines and decreases drug resistance independent of MGMT activity and PTEN proficiency.
    Oncology reports, 2020, Volume: 44, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cell Line, Tumor; DNA Modification Me

2020
PARP‑1 inhibition sensitizes temozolomide‑treated glioblastoma cell lines and decreases drug resistance independent of MGMT activity and PTEN proficiency.
    Oncology reports, 2020, Volume: 44, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cell Line, Tumor; DNA Modification Me

2020
PARP‑1 inhibition sensitizes temozolomide‑treated glioblastoma cell lines and decreases drug resistance independent of MGMT activity and PTEN proficiency.
    Oncology reports, 2020, Volume: 44, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cell Line, Tumor; DNA Modification Me

2020
LINC00470 promotes tumour proliferation and invasion, and attenuates chemosensitivity through the LINC00470/miR-134/Myc/ABCC1 axis in glioma.
    Journal of cellular and molecular medicine, 2020, Volume: 24, Issue:20

    Topics: Base Sequence; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Gene Expression Regulation, Ne

2020
LINC00470 promotes tumour proliferation and invasion, and attenuates chemosensitivity through the LINC00470/miR-134/Myc/ABCC1 axis in glioma.
    Journal of cellular and molecular medicine, 2020, Volume: 24, Issue:20

    Topics: Base Sequence; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Gene Expression Regulation, Ne

2020
LINC00470 promotes tumour proliferation and invasion, and attenuates chemosensitivity through the LINC00470/miR-134/Myc/ABCC1 axis in glioma.
    Journal of cellular and molecular medicine, 2020, Volume: 24, Issue:20

    Topics: Base Sequence; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Gene Expression Regulation, Ne

2020
A facile and scalable in production non-viral gene engineered mesenchymal stem cells for effective suppression of temozolomide-resistant (TMZR) glioblastoma growth.
    Stem cell research & therapy, 2020, 09-11, Volume: 11, Issue:1

    Topics: Animals; Brain Neoplasms; Cell Line, Tumor; Glioblastoma; Humans; Mesenchymal Stem Cells; Mice; Mice

2020
A facile and scalable in production non-viral gene engineered mesenchymal stem cells for effective suppression of temozolomide-resistant (TMZR) glioblastoma growth.
    Stem cell research & therapy, 2020, 09-11, Volume: 11, Issue:1

    Topics: Animals; Brain Neoplasms; Cell Line, Tumor; Glioblastoma; Humans; Mesenchymal Stem Cells; Mice; Mice

2020
A facile and scalable in production non-viral gene engineered mesenchymal stem cells for effective suppression of temozolomide-resistant (TMZR) glioblastoma growth.
    Stem cell research & therapy, 2020, 09-11, Volume: 11, Issue:1

    Topics: Animals; Brain Neoplasms; Cell Line, Tumor; Glioblastoma; Humans; Mesenchymal Stem Cells; Mice; Mice

2020
EIF4A3-induced circular RNA ASAP1 promotes tumorigenesis and temozolomide resistance of glioblastoma via NRAS/MEK1/ERK1-2 signaling.
    Neuro-oncology, 2021, 04-12, Volume: 23, Issue:4

    Topics: Adaptor Proteins, Signal Transducing; Brain Neoplasms; Carcinogenesis; Cell Line, Tumor; Cell Prolif

2021
EIF4A3-induced circular RNA ASAP1 promotes tumorigenesis and temozolomide resistance of glioblastoma via NRAS/MEK1/ERK1-2 signaling.
    Neuro-oncology, 2021, 04-12, Volume: 23, Issue:4

    Topics: Adaptor Proteins, Signal Transducing; Brain Neoplasms; Carcinogenesis; Cell Line, Tumor; Cell Prolif

2021
EIF4A3-induced circular RNA ASAP1 promotes tumorigenesis and temozolomide resistance of glioblastoma via NRAS/MEK1/ERK1-2 signaling.
    Neuro-oncology, 2021, 04-12, Volume: 23, Issue:4

    Topics: Adaptor Proteins, Signal Transducing; Brain Neoplasms; Carcinogenesis; Cell Line, Tumor; Cell Prolif

2021
Acute interstitial nephritis and nephrogenic diabetes insipidus following treatment with sulfamethoxazole-trimethoprim and temozolomide.
    Nephrology (Carlton, Vic.), 2021, Volume: 26, Issue:1

    Topics: Acute Kidney Injury; Anti-Bacterial Agents; Antineoplastic Agents, Alkylating; Brain Neoplasms; Diab

2021
Acute interstitial nephritis and nephrogenic diabetes insipidus following treatment with sulfamethoxazole-trimethoprim and temozolomide.
    Nephrology (Carlton, Vic.), 2021, Volume: 26, Issue:1

    Topics: Acute Kidney Injury; Anti-Bacterial Agents; Antineoplastic Agents, Alkylating; Brain Neoplasms; Diab

2021
Acute interstitial nephritis and nephrogenic diabetes insipidus following treatment with sulfamethoxazole-trimethoprim and temozolomide.
    Nephrology (Carlton, Vic.), 2021, Volume: 26, Issue:1

    Topics: Acute Kidney Injury; Anti-Bacterial Agents; Antineoplastic Agents, Alkylating; Brain Neoplasms; Diab

2021
Patterns of recurrence and outcomes of glioblastoma multiforme treated with chemoradiation and adjuvant temozolomide.
    Clinics (Sao Paulo, Brazil), 2020, Volume: 75

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Brazil; Chemoradiotherapy; Chemotherapy, Adjuvan

2020
Patterns of recurrence and outcomes of glioblastoma multiforme treated with chemoradiation and adjuvant temozolomide.
    Clinics (Sao Paulo, Brazil), 2020, Volume: 75

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Brazil; Chemoradiotherapy; Chemotherapy, Adjuvan

2020
Patterns of recurrence and outcomes of glioblastoma multiforme treated with chemoradiation and adjuvant temozolomide.
    Clinics (Sao Paulo, Brazil), 2020, Volume: 75

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Brazil; Chemoradiotherapy; Chemotherapy, Adjuvan

2020
Can 3D-CRT meet the desired dose distribution to target and OARs in glioblastoma? A tertiary cancer center experience.
    CNS oncology, 2020, 09-01, Volume: 9, Issue:3

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Female; Glioblastoma; Humans;

2020
Can 3D-CRT meet the desired dose distribution to target and OARs in glioblastoma? A tertiary cancer center experience.
    CNS oncology, 2020, 09-01, Volume: 9, Issue:3

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Female; Glioblastoma; Humans;

2020
Can 3D-CRT meet the desired dose distribution to target and OARs in glioblastoma? A tertiary cancer center experience.
    CNS oncology, 2020, 09-01, Volume: 9, Issue:3

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Female; Glioblastoma; Humans;

2020
Sphingosine‑1‑phosphate analogue FTY720 exhibits a potent anti‑proliferative effect on glioblastoma cells.
    International journal of oncology, 2020, Volume: 57, Issue:4

    Topics: Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cell Cycle; Cell Line, Tumor; Cell Pr

2020
Sphingosine‑1‑phosphate analogue FTY720 exhibits a potent anti‑proliferative effect on glioblastoma cells.
    International journal of oncology, 2020, Volume: 57, Issue:4

    Topics: Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cell Cycle; Cell Line, Tumor; Cell Pr

2020
Sphingosine‑1‑phosphate analogue FTY720 exhibits a potent anti‑proliferative effect on glioblastoma cells.
    International journal of oncology, 2020, Volume: 57, Issue:4

    Topics: Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cell Cycle; Cell Line, Tumor; Cell Pr

2020
A case of pediatric gliomatosis cerebri harboring H3F3A K27 mutation.
    Pediatric blood & cancer, 2020, Volume: 67, Issue:9

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Child; Female; Histones; Humans; Magnetic Resona

2020
A case of pediatric gliomatosis cerebri harboring H3F3A K27 mutation.
    Pediatric blood & cancer, 2020, Volume: 67, Issue:9

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Child; Female; Histones; Humans; Magnetic Resona

2020
A case of pediatric gliomatosis cerebri harboring H3F3A K27 mutation.
    Pediatric blood & cancer, 2020, Volume: 67, Issue:9

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Child; Female; Histones; Humans; Magnetic Resona

2020
Z-scan method to measure the nonlinear optical behavior of cells for evaluating the cytotoxic effects of chemotherapy and hyperthermia treatments.
    Lasers in medical science, 2021, Volume: 36, Issue:5

    Topics: Antineoplastic Agents; Brain Neoplasms; Cell Line, Tumor; Humans; Hyperthermia, Induced; Nonlinear D

2021
Z-scan method to measure the nonlinear optical behavior of cells for evaluating the cytotoxic effects of chemotherapy and hyperthermia treatments.
    Lasers in medical science, 2021, Volume: 36, Issue:5

    Topics: Antineoplastic Agents; Brain Neoplasms; Cell Line, Tumor; Humans; Hyperthermia, Induced; Nonlinear D

2021
Z-scan method to measure the nonlinear optical behavior of cells for evaluating the cytotoxic effects of chemotherapy and hyperthermia treatments.
    Lasers in medical science, 2021, Volume: 36, Issue:5

    Topics: Antineoplastic Agents; Brain Neoplasms; Cell Line, Tumor; Humans; Hyperthermia, Induced; Nonlinear D

2021
Survival benefit of concomitant chemoradiation in adult supratentorial primary glioblastoma. A propensity score weighted population-based analysis.
    Journal of neurosurgical sciences, 2022, Volume: 66, Issue:6

    Topics: Adult; Brain Neoplasms; Glioblastoma; Humans; Kaplan-Meier Estimate; Propensity Score; Supratentoria

2022
Survival benefit of concomitant chemoradiation in adult supratentorial primary glioblastoma. A propensity score weighted population-based analysis.
    Journal of neurosurgical sciences, 2022, Volume: 66, Issue:6

    Topics: Adult; Brain Neoplasms; Glioblastoma; Humans; Kaplan-Meier Estimate; Propensity Score; Supratentoria

2022
Survival benefit of concomitant chemoradiation in adult supratentorial primary glioblastoma. A propensity score weighted population-based analysis.
    Journal of neurosurgical sciences, 2022, Volume: 66, Issue:6

    Topics: Adult; Brain Neoplasms; Glioblastoma; Humans; Kaplan-Meier Estimate; Propensity Score; Supratentoria

2022
Downregulation of hsa_circ_0000936 sensitizes resistant glioma cells to temozolomide by sponging miR-1294.
    Journal of biosciences, 2020, Volume: 45

    Topics: Antineoplastic Agents, Alkylating; Apoptosis; Base Pairing; Base Sequence; Brain Neoplasms; Cell Lin

2020
Downregulation of hsa_circ_0000936 sensitizes resistant glioma cells to temozolomide by sponging miR-1294.
    Journal of biosciences, 2020, Volume: 45

    Topics: Antineoplastic Agents, Alkylating; Apoptosis; Base Pairing; Base Sequence; Brain Neoplasms; Cell Lin

2020
Downregulation of hsa_circ_0000936 sensitizes resistant glioma cells to temozolomide by sponging miR-1294.
    Journal of biosciences, 2020, Volume: 45

    Topics: Antineoplastic Agents, Alkylating; Apoptosis; Base Pairing; Base Sequence; Brain Neoplasms; Cell Lin

2020
Clinical Efficacy of Tumor Treating Fields for Newly Diagnosed Glioblastoma.
    Anticancer research, 2020, Volume: 40, Issue:10

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modalit

2020
Clinical Efficacy of Tumor Treating Fields for Newly Diagnosed Glioblastoma.
    Anticancer research, 2020, Volume: 40, Issue:10

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modalit

2020
Clinical Efficacy of Tumor Treating Fields for Newly Diagnosed Glioblastoma.
    Anticancer research, 2020, Volume: 40, Issue:10

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modalit

2020
Central diabetes insipidus induced by temozolomide: A report of two cases.
    Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners, 2021, Volume: 27, Issue:4

    Topics: Adult; Antineoplastic Agents, Alkylating; Brain Neoplasms; Deamino Arginine Vasopressin; Diabetes In

2021
Central diabetes insipidus induced by temozolomide: A report of two cases.
    Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners, 2021, Volume: 27, Issue:4

    Topics: Adult; Antineoplastic Agents, Alkylating; Brain Neoplasms; Deamino Arginine Vasopressin; Diabetes In

2021
Central diabetes insipidus induced by temozolomide: A report of two cases.
    Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners, 2021, Volume: 27, Issue:4

    Topics: Adult; Antineoplastic Agents, Alkylating; Brain Neoplasms; Deamino Arginine Vasopressin; Diabetes In

2021
MGMT methylation may benefit overall survival in patients with moderately vascularized glioblastomas.
    European radiology, 2021, Volume: 31, Issue:3

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; DNA Methylation; DNA Modification Methylases; DN

2021
MGMT methylation may benefit overall survival in patients with moderately vascularized glioblastomas.
    European radiology, 2021, Volume: 31, Issue:3

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; DNA Methylation; DNA Modification Methylases; DN

2021
MGMT methylation may benefit overall survival in patients with moderately vascularized glioblastomas.
    European radiology, 2021, Volume: 31, Issue:3

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; DNA Methylation; DNA Modification Methylases; DN

2021
Patient-derived organoids and orthotopic xenografts of primary and recurrent gliomas represent relevant patient avatars for precision oncology.
    Acta neuropathologica, 2020, Volume: 140, Issue:6

    Topics: Animals; Brain Neoplasms; Glioblastoma; Glioma; Heterografts; Humans; Mice; Neoplasm Recurrence, Loc

2020
Patient-derived organoids and orthotopic xenografts of primary and recurrent gliomas represent relevant patient avatars for precision oncology.
    Acta neuropathologica, 2020, Volume: 140, Issue:6

    Topics: Animals; Brain Neoplasms; Glioblastoma; Glioma; Heterografts; Humans; Mice; Neoplasm Recurrence, Loc

2020
Patient-derived organoids and orthotopic xenografts of primary and recurrent gliomas represent relevant patient avatars for precision oncology.
    Acta neuropathologica, 2020, Volume: 140, Issue:6

    Topics: Animals; Brain Neoplasms; Glioblastoma; Glioma; Heterografts; Humans; Mice; Neoplasm Recurrence, Loc

2020
Epigenetic modulator inhibition overcomes temozolomide chemoresistance and antagonizes tumor recurrence of glioblastoma.
    The Journal of clinical investigation, 2020, 11-02, Volume: 130, Issue:11

    Topics: Animals; Brain Neoplasms; Cell Line, Tumor; DNA Methylation; DNA, Neoplasm; Drug Resistance, Neoplas

2020
Epigenetic modulator inhibition overcomes temozolomide chemoresistance and antagonizes tumor recurrence of glioblastoma.
    The Journal of clinical investigation, 2020, 11-02, Volume: 130, Issue:11

    Topics: Animals; Brain Neoplasms; Cell Line, Tumor; DNA Methylation; DNA, Neoplasm; Drug Resistance, Neoplas

2020
Epigenetic modulator inhibition overcomes temozolomide chemoresistance and antagonizes tumor recurrence of glioblastoma.
    The Journal of clinical investigation, 2020, 11-02, Volume: 130, Issue:11

    Topics: Animals; Brain Neoplasms; Cell Line, Tumor; DNA Methylation; DNA, Neoplasm; Drug Resistance, Neoplas

2020
Combination therapy of cold atmospheric plasma (CAP) with temozolomide in the treatment of U87MG glioblastoma cells.
    Scientific reports, 2020, 10-05, Volume: 10, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cell Movement; Cell

2020
Combination therapy of cold atmospheric plasma (CAP) with temozolomide in the treatment of U87MG glioblastoma cells.
    Scientific reports, 2020, 10-05, Volume: 10, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cell Movement; Cell

2020
Combination therapy of cold atmospheric plasma (CAP) with temozolomide in the treatment of U87MG glioblastoma cells.
    Scientific reports, 2020, 10-05, Volume: 10, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cell Movement; Cell

2020
Identification of a three-long non-coding RNA signature for predicting survival of temozolomide-treated isocitrate dehydrogenase mutant low-grade gliomas.
    Experimental biology and medicine (Maywood, N.J.), 2021, Volume: 246, Issue:2

    Topics: Adult; Aged; Brain Neoplasms; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplas

2021
Identification of a three-long non-coding RNA signature for predicting survival of temozolomide-treated isocitrate dehydrogenase mutant low-grade gliomas.
    Experimental biology and medicine (Maywood, N.J.), 2021, Volume: 246, Issue:2

    Topics: Adult; Aged; Brain Neoplasms; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplas

2021
Identification of a three-long non-coding RNA signature for predicting survival of temozolomide-treated isocitrate dehydrogenase mutant low-grade gliomas.
    Experimental biology and medicine (Maywood, N.J.), 2021, Volume: 246, Issue:2

    Topics: Adult; Aged; Brain Neoplasms; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplas

2021
LncRNA NEAT1 promotes malignant phenotypes and TMZ resistance in glioblastoma stem cells by regulating let-7g-5p/MAP3K1 axis.
    Bioscience reports, 2020, 10-30, Volume: 40, Issue:10

    Topics: Brain Neoplasms; Case-Control Studies; Cell Line, Tumor; Cell Movement; Cell Proliferation; Drug Res

2020
LncRNA NEAT1 promotes malignant phenotypes and TMZ resistance in glioblastoma stem cells by regulating let-7g-5p/MAP3K1 axis.
    Bioscience reports, 2020, 10-30, Volume: 40, Issue:10

    Topics: Brain Neoplasms; Case-Control Studies; Cell Line, Tumor; Cell Movement; Cell Proliferation; Drug Res

2020
LncRNA NEAT1 promotes malignant phenotypes and TMZ resistance in glioblastoma stem cells by regulating let-7g-5p/MAP3K1 axis.
    Bioscience reports, 2020, 10-30, Volume: 40, Issue:10

    Topics: Brain Neoplasms; Case-Control Studies; Cell Line, Tumor; Cell Movement; Cell Proliferation; Drug Res

2020
Penetrating the brain tumor space with DNA damage response inhibitors.
    Neuro-oncology, 2020, 12-18, Volume: 22, Issue:12

    Topics: Brain Neoplasms; DNA Damage; Glioblastoma; Humans; Phthalazines; Piperazines; Temozolomide

2020
Penetrating the brain tumor space with DNA damage response inhibitors.
    Neuro-oncology, 2020, 12-18, Volume: 22, Issue:12

    Topics: Brain Neoplasms; DNA Damage; Glioblastoma; Humans; Phthalazines; Piperazines; Temozolomide

2020
Penetrating the brain tumor space with DNA damage response inhibitors.
    Neuro-oncology, 2020, 12-18, Volume: 22, Issue:12

    Topics: Brain Neoplasms; DNA Damage; Glioblastoma; Humans; Phthalazines; Piperazines; Temozolomide

2020
Spatiotemporal combination of thermosensitive polypeptide fused interferon and temozolomide for post-surgical glioblastoma immunochemotherapy.
    Biomaterials, 2021, Volume: 264

    Topics: Animals; Brain Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; Glioblastoma; Mice; Neoplasm

2021
Spatiotemporal combination of thermosensitive polypeptide fused interferon and temozolomide for post-surgical glioblastoma immunochemotherapy.
    Biomaterials, 2021, Volume: 264

    Topics: Animals; Brain Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; Glioblastoma; Mice; Neoplasm

2021
Spatiotemporal combination of thermosensitive polypeptide fused interferon and temozolomide for post-surgical glioblastoma immunochemotherapy.
    Biomaterials, 2021, Volume: 264

    Topics: Animals; Brain Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; Glioblastoma; Mice; Neoplasm

2021
Mutant IDH1 Enhances Temozolomide Sensitivity via Regulation of the ATM/CHK2 Pathway in Glioma.
    Cancer research and treatment, 2021, Volume: 53, Issue:2

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Female; Glioma; Human

2021
Mutant IDH1 Enhances Temozolomide Sensitivity via Regulation of the ATM/CHK2 Pathway in Glioma.
    Cancer research and treatment, 2021, Volume: 53, Issue:2

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Female; Glioma; Human

2021
Mutant IDH1 Enhances Temozolomide Sensitivity via Regulation of the ATM/CHK2 Pathway in Glioma.
    Cancer research and treatment, 2021, Volume: 53, Issue:2

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Female; Glioma; Human

2021
Combination of levetiracetam and IFN-α increased temozolomide efficacy in MGMT-positive glioma.
    Cancer chemotherapy and pharmacology, 2020, Volume: 86, Issue:6

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Cell Line, Tumor; DNA Modi

2020
Combination of levetiracetam and IFN-α increased temozolomide efficacy in MGMT-positive glioma.
    Cancer chemotherapy and pharmacology, 2020, Volume: 86, Issue:6

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Cell Line, Tumor; DNA Modi

2020
Combination of levetiracetam and IFN-α increased temozolomide efficacy in MGMT-positive glioma.
    Cancer chemotherapy and pharmacology, 2020, Volume: 86, Issue:6

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Cell Line, Tumor; DNA Modi

2020
Clinical characterization of glioblastoma patients living longer than 2 years: A retrospective analysis of two Italian institutions.
    Asia-Pacific journal of clinical oncology, 2021, Volume: 17, Issue:3

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Female; Glioblas

2021
Clinical characterization of glioblastoma patients living longer than 2 years: A retrospective analysis of two Italian institutions.
    Asia-Pacific journal of clinical oncology, 2021, Volume: 17, Issue:3

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Female; Glioblas

2021
Clinical characterization of glioblastoma patients living longer than 2 years: A retrospective analysis of two Italian institutions.
    Asia-Pacific journal of clinical oncology, 2021, Volume: 17, Issue:3

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Female; Glioblas

2021
Enhanced Caspase-Mediated Abrogation of Autophagy by Temozolomide-Loaded and Panitumumab-Conjugated Poly(lactic-
    Molecular pharmaceutics, 2020, 11-02, Volume: 17, Issue:11

    Topics: Antineoplastic Agents; Apoptosis; Autophagy; Brain Neoplasms; Caspase 9; Cell Line, Tumor; Cell Surv

2020
Enhanced Caspase-Mediated Abrogation of Autophagy by Temozolomide-Loaded and Panitumumab-Conjugated Poly(lactic-
    Molecular pharmaceutics, 2020, 11-02, Volume: 17, Issue:11

    Topics: Antineoplastic Agents; Apoptosis; Autophagy; Brain Neoplasms; Caspase 9; Cell Line, Tumor; Cell Surv

2020
Enhanced Caspase-Mediated Abrogation of Autophagy by Temozolomide-Loaded and Panitumumab-Conjugated Poly(lactic-
    Molecular pharmaceutics, 2020, 11-02, Volume: 17, Issue:11

    Topics: Antineoplastic Agents; Apoptosis; Autophagy; Brain Neoplasms; Caspase 9; Cell Line, Tumor; Cell Surv

2020
Reduced EGFR and increased miR-221 is associated with increased resistance to temozolomide and radiotherapy in glioblastoma.
    Scientific reports, 2020, 10-20, Volume: 10, Issue:1

    Topics: Antineoplastic Agents; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Chemoradiotherapy; Drug Resista

2020
Reduced EGFR and increased miR-221 is associated with increased resistance to temozolomide and radiotherapy in glioblastoma.
    Scientific reports, 2020, 10-20, Volume: 10, Issue:1

    Topics: Antineoplastic Agents; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Chemoradiotherapy; Drug Resista

2020
Reduced EGFR and increased miR-221 is associated with increased resistance to temozolomide and radiotherapy in glioblastoma.
    Scientific reports, 2020, 10-20, Volume: 10, Issue:1

    Topics: Antineoplastic Agents; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Chemoradiotherapy; Drug Resista

2020
Cytotoxic lanthanum oxide nanoparticles sensitize glioblastoma cells to radiation therapy and temozolomide: an in vitro rationale for translational studies.
    Scientific reports, 2020, 10-23, Volume: 10, Issue:1

    Topics: Animals; Apoptosis; Brain; Brain Neoplasms; Cell Line, Tumor; Cell Survival; Chemoradiotherapy; Drug

2020
Cytotoxic lanthanum oxide nanoparticles sensitize glioblastoma cells to radiation therapy and temozolomide: an in vitro rationale for translational studies.
    Scientific reports, 2020, 10-23, Volume: 10, Issue:1

    Topics: Animals; Apoptosis; Brain; Brain Neoplasms; Cell Line, Tumor; Cell Survival; Chemoradiotherapy; Drug

2020
Cytotoxic lanthanum oxide nanoparticles sensitize glioblastoma cells to radiation therapy and temozolomide: an in vitro rationale for translational studies.
    Scientific reports, 2020, 10-23, Volume: 10, Issue:1

    Topics: Animals; Apoptosis; Brain; Brain Neoplasms; Cell Line, Tumor; Cell Survival; Chemoradiotherapy; Drug

2020
Simvastatin Induces Unfolded Protein Response and Enhances Temozolomide-Induced Cell Death in Glioblastoma Cells.
    Cells, 2020, 10-22, Volume: 9, Issue:11

    Topics: Antineoplastic Agents; Apoptosis; Brain Neoplasms; Caspases; Cell Death; Cell Line, Tumor; Cell Surv

2020
Simvastatin Induces Unfolded Protein Response and Enhances Temozolomide-Induced Cell Death in Glioblastoma Cells.
    Cells, 2020, 10-22, Volume: 9, Issue:11

    Topics: Antineoplastic Agents; Apoptosis; Brain Neoplasms; Caspases; Cell Death; Cell Line, Tumor; Cell Surv

2020
Simvastatin Induces Unfolded Protein Response and Enhances Temozolomide-Induced Cell Death in Glioblastoma Cells.
    Cells, 2020, 10-22, Volume: 9, Issue:11

    Topics: Antineoplastic Agents; Apoptosis; Brain Neoplasms; Caspases; Cell Death; Cell Line, Tumor; Cell Surv

2020
Temozolomide treatment combined with AZD3463 shows synergistic effect in glioblastoma cells.
    Biochemical and biophysical research communications, 2020, 12-17, Volume: 533, Issue:4

    Topics: Anaplastic Lymphoma Kinase; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Brain Neoplas

2020
Temozolomide treatment combined with AZD3463 shows synergistic effect in glioblastoma cells.
    Biochemical and biophysical research communications, 2020, 12-17, Volume: 533, Issue:4

    Topics: Anaplastic Lymphoma Kinase; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Brain Neoplas

2020
Temozolomide treatment combined with AZD3463 shows synergistic effect in glioblastoma cells.
    Biochemical and biophysical research communications, 2020, 12-17, Volume: 533, Issue:4

    Topics: Anaplastic Lymphoma Kinase; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Brain Neoplas

2020
Synthetic Betulin Derivatives Inhibit Growth of Glioma Cells
    Anticancer research, 2020, Volume: 40, Issue:11

    Topics: Acetylene; Animals; Apoptosis; Brain Neoplasms; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Ce

2020
Synthetic Betulin Derivatives Inhibit Growth of Glioma Cells
    Anticancer research, 2020, Volume: 40, Issue:11

    Topics: Acetylene; Animals; Apoptosis; Brain Neoplasms; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Ce

2020
Synthetic Betulin Derivatives Inhibit Growth of Glioma Cells
    Anticancer research, 2020, Volume: 40, Issue:11

    Topics: Acetylene; Animals; Apoptosis; Brain Neoplasms; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Ce

2020
Encapsulation of Small Drugs in a Supramolecule Enhances Solubility, Stability, and Therapeutic Efficacy Against Glioblastoma Multiforme.
    Methods in molecular biology (Clifton, N.J.), 2021, Volume: 2207

    Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Cell Line, Tumor; Drug Carriers; Female; Glioblasto

2021
Encapsulation of Small Drugs in a Supramolecule Enhances Solubility, Stability, and Therapeutic Efficacy Against Glioblastoma Multiforme.
    Methods in molecular biology (Clifton, N.J.), 2021, Volume: 2207

    Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Cell Line, Tumor; Drug Carriers; Female; Glioblasto

2021
Encapsulation of Small Drugs in a Supramolecule Enhances Solubility, Stability, and Therapeutic Efficacy Against Glioblastoma Multiforme.
    Methods in molecular biology (Clifton, N.J.), 2021, Volume: 2207

    Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Cell Line, Tumor; Drug Carriers; Female; Glioblasto

2021
Hepatitis B virus reactivation during temozolomide administration for malignant glioma.
    International journal of clinical oncology, 2021, Volume: 26, Issue:2

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; DNA, Viral; Glioma; Hepatitis B; Hepatitis B Ant

2021
Hepatitis B virus reactivation during temozolomide administration for malignant glioma.
    International journal of clinical oncology, 2021, Volume: 26, Issue:2

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; DNA, Viral; Glioma; Hepatitis B; Hepatitis B Ant

2021
Hepatitis B virus reactivation during temozolomide administration for malignant glioma.
    International journal of clinical oncology, 2021, Volume: 26, Issue:2

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; DNA, Viral; Glioma; Hepatitis B; Hepatitis B Ant

2021
Actual body weight dosing of temozolomide and overall survival in patients with glioblastoma.
    Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners, 2021, Volume: 27, Issue:7

    Topics: Adult; Antineoplastic Agents, Alkylating; Body Weight; Brain Neoplasms; Combined Modality Therapy; D

2021
Actual body weight dosing of temozolomide and overall survival in patients with glioblastoma.
    Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners, 2021, Volume: 27, Issue:7

    Topics: Adult; Antineoplastic Agents, Alkylating; Body Weight; Brain Neoplasms; Combined Modality Therapy; D

2021
Actual body weight dosing of temozolomide and overall survival in patients with glioblastoma.
    Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners, 2021, Volume: 27, Issue:7

    Topics: Adult; Antineoplastic Agents, Alkylating; Body Weight; Brain Neoplasms; Combined Modality Therapy; D

2021
Memory in low-grade glioma patients treated with radiotherapy or temozolomide: a correlative analysis of EORTC study 22033-26033.
    Neuro-oncology, 2021, 05-05, Volume: 23, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Glioma; Humans; Progression-Free Survival; Temoz

2021
Memory in low-grade glioma patients treated with radiotherapy or temozolomide: a correlative analysis of EORTC study 22033-26033.
    Neuro-oncology, 2021, 05-05, Volume: 23, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Glioma; Humans; Progression-Free Survival; Temoz

2021
Memory in low-grade glioma patients treated with radiotherapy or temozolomide: a correlative analysis of EORTC study 22033-26033.
    Neuro-oncology, 2021, 05-05, Volume: 23, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Glioma; Humans; Progression-Free Survival; Temoz

2021
Cell-free DNA and circulating TERT promoter mutation for disease monitoring in newly-diagnosed glioblastoma.
    Acta neuropathologica communications, 2020, 11-04, Volume: 8, Issue:1

    Topics: Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell-Free Nucleic Acids; Chemoradiotherapy

2020
Cell-free DNA and circulating TERT promoter mutation for disease monitoring in newly-diagnosed glioblastoma.
    Acta neuropathologica communications, 2020, 11-04, Volume: 8, Issue:1

    Topics: Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell-Free Nucleic Acids; Chemoradiotherapy

2020
Cell-free DNA and circulating TERT promoter mutation for disease monitoring in newly-diagnosed glioblastoma.
    Acta neuropathologica communications, 2020, 11-04, Volume: 8, Issue:1

    Topics: Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell-Free Nucleic Acids; Chemoradiotherapy

2020
[Cathepsin S (CTSS) is highly expressed in temozolomide-resistant glioblastoma T98G cells and associated with poor prognosis].
    Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology, 2020, Volume: 36, Issue:10

    Topics: Brain Neoplasms; Cathepsins; Cell Line, Tumor; Drug Resistance, Neoplasm; Gene Expression Regulation

2020
[Cathepsin S (CTSS) is highly expressed in temozolomide-resistant glioblastoma T98G cells and associated with poor prognosis].
    Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology, 2020, Volume: 36, Issue:10

    Topics: Brain Neoplasms; Cathepsins; Cell Line, Tumor; Drug Resistance, Neoplasm; Gene Expression Regulation

2020
[Cathepsin S (CTSS) is highly expressed in temozolomide-resistant glioblastoma T98G cells and associated with poor prognosis].
    Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology, 2020, Volume: 36, Issue:10

    Topics: Brain Neoplasms; Cathepsins; Cell Line, Tumor; Drug Resistance, Neoplasm; Gene Expression Regulation

2020
Methylation associated miR-1246 contributes to poor prognosis in gliomas treated with temozolomide.
    Clinical neurology and neurosurgery, 2021, Volume: 200

    Topics: Brain Neoplasms; Cell Proliferation; Gene Expression Regulation, Neoplastic; Glioblastoma; Glioma; H

2021
Methylation associated miR-1246 contributes to poor prognosis in gliomas treated with temozolomide.
    Clinical neurology and neurosurgery, 2021, Volume: 200

    Topics: Brain Neoplasms; Cell Proliferation; Gene Expression Regulation, Neoplastic; Glioblastoma; Glioma; H

2021
Methylation associated miR-1246 contributes to poor prognosis in gliomas treated with temozolomide.
    Clinical neurology and neurosurgery, 2021, Volume: 200

    Topics: Brain Neoplasms; Cell Proliferation; Gene Expression Regulation, Neoplastic; Glioblastoma; Glioma; H

2021
Early Treatment Response Assessment Using
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2021, 07-01, Volume: 62, Issue:7

    Topics: Adult; Aged; Brain Neoplasms; Glioma; Humans; Middle Aged; Temozolomide; Young Adult

2021
Early Treatment Response Assessment Using
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2021, 07-01, Volume: 62, Issue:7

    Topics: Adult; Aged; Brain Neoplasms; Glioma; Humans; Middle Aged; Temozolomide; Young Adult

2021
Early Treatment Response Assessment Using
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2021, 07-01, Volume: 62, Issue:7

    Topics: Adult; Aged; Brain Neoplasms; Glioma; Humans; Middle Aged; Temozolomide; Young Adult

2021
Mitochondrial dysfunction contributes to Rapamycin-induced apoptosis of Human Glioblastoma Cells - A synergistic effect with Temozolomide.
    International journal of medical sciences, 2020, Volume: 17, Issue:17

    Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cell S

2020
Mitochondrial dysfunction contributes to Rapamycin-induced apoptosis of Human Glioblastoma Cells - A synergistic effect with Temozolomide.
    International journal of medical sciences, 2020, Volume: 17, Issue:17

    Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cell S

2020
Mitochondrial dysfunction contributes to Rapamycin-induced apoptosis of Human Glioblastoma Cells - A synergistic effect with Temozolomide.
    International journal of medical sciences, 2020, Volume: 17, Issue:17

    Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cell S

2020
Loss of PLK2 induces acquired resistance to temozolomide in GBM via activation of notch signaling.
    Journal of experimental & clinical cancer research : CR, 2020, Nov-11, Volume: 39, Issue:1

    Topics: Animals; Brain Neoplasms; Female; Glioblastoma; Humans; Mice; Mice, Nude; Protein Serine-Threonine K

2020
Loss of PLK2 induces acquired resistance to temozolomide in GBM via activation of notch signaling.
    Journal of experimental & clinical cancer research : CR, 2020, Nov-11, Volume: 39, Issue:1

    Topics: Animals; Brain Neoplasms; Female; Glioblastoma; Humans; Mice; Mice, Nude; Protein Serine-Threonine K

2020
Loss of PLK2 induces acquired resistance to temozolomide in GBM via activation of notch signaling.
    Journal of experimental & clinical cancer research : CR, 2020, Nov-11, Volume: 39, Issue:1

    Topics: Animals; Brain Neoplasms; Female; Glioblastoma; Humans; Mice; Mice, Nude; Protein Serine-Threonine K

2020
Unraveling response to temozolomide in preclinical GL261 glioblastoma with MRI/MRSI using radiomics and signal source extraction.
    Scientific reports, 2020, 11-12, Volume: 10, Issue:1

    Topics: Animals; Brain Neoplasms; Cell Line, Tumor; Glioblastoma; Humans; Machine Learning; Magnetic Resonan

2020
Unraveling response to temozolomide in preclinical GL261 glioblastoma with MRI/MRSI using radiomics and signal source extraction.
    Scientific reports, 2020, 11-12, Volume: 10, Issue:1

    Topics: Animals; Brain Neoplasms; Cell Line, Tumor; Glioblastoma; Humans; Machine Learning; Magnetic Resonan

2020
Unraveling response to temozolomide in preclinical GL261 glioblastoma with MRI/MRSI using radiomics and signal source extraction.
    Scientific reports, 2020, 11-12, Volume: 10, Issue:1

    Topics: Animals; Brain Neoplasms; Cell Line, Tumor; Glioblastoma; Humans; Machine Learning; Magnetic Resonan

2020
Circ-VPS18 Knockdown Enhances TMZ Sensitivity and Inhibits Glioma Progression by MiR-370/RUNX1 Axis.
    Journal of molecular neuroscience : MN, 2021, Volume: 71, Issue:6

    Topics: Animals; Antineoplastic Agents, Alkylating; Apoptosis; ATP Binding Cassette Transporter, Subfamily B

2021
Circ-VPS18 Knockdown Enhances TMZ Sensitivity and Inhibits Glioma Progression by MiR-370/RUNX1 Axis.
    Journal of molecular neuroscience : MN, 2021, Volume: 71, Issue:6

    Topics: Animals; Antineoplastic Agents, Alkylating; Apoptosis; ATP Binding Cassette Transporter, Subfamily B

2021
Circ-VPS18 Knockdown Enhances TMZ Sensitivity and Inhibits Glioma Progression by MiR-370/RUNX1 Axis.
    Journal of molecular neuroscience : MN, 2021, Volume: 71, Issue:6

    Topics: Animals; Antineoplastic Agents, Alkylating; Apoptosis; ATP Binding Cassette Transporter, Subfamily B

2021
Smarcd1 Inhibits the Malignant Phenotypes of Human Glioblastoma Cells via Crosstalk with Notch1.
    Molecular neurobiology, 2021, Volume: 58, Issue:4

    Topics: Animals; Apoptosis; Brain Neoplasms; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Movement; Cell P

2021
Smarcd1 Inhibits the Malignant Phenotypes of Human Glioblastoma Cells via Crosstalk with Notch1.
    Molecular neurobiology, 2021, Volume: 58, Issue:4

    Topics: Animals; Apoptosis; Brain Neoplasms; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Movement; Cell P

2021
Smarcd1 Inhibits the Malignant Phenotypes of Human Glioblastoma Cells via Crosstalk with Notch1.
    Molecular neurobiology, 2021, Volume: 58, Issue:4

    Topics: Animals; Apoptosis; Brain Neoplasms; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Movement; Cell P

2021
Assessment of MGMT methylation status using high-performance liquid chromatography in newly diagnosed glioblastoma.
    Clinical epigenetics, 2020, 11-17, Volume: 12, Issue:1

    Topics: Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chromatography, High Pressure Liquid; CpG

2020
Assessment of MGMT methylation status using high-performance liquid chromatography in newly diagnosed glioblastoma.
    Clinical epigenetics, 2020, 11-17, Volume: 12, Issue:1

    Topics: Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chromatography, High Pressure Liquid; CpG

2020
Assessment of MGMT methylation status using high-performance liquid chromatography in newly diagnosed glioblastoma.
    Clinical epigenetics, 2020, 11-17, Volume: 12, Issue:1

    Topics: Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chromatography, High Pressure Liquid; CpG

2020
Comparison of Elemental Anomalies Following Implantation of Different Cell Lines of Glioblastoma Multiforme in the Rat Brain: A Total Reflection X-ray Fluorescence Spectroscopy Study.
    ACS chemical neuroscience, 2020, 12-16, Volume: 11, Issue:24

    Topics: Animals; Brain; Brain Neoplasms; Cell Line, Tumor; Glioblastoma; Humans; Rats; Spectrometry, X-Ray E

2020
Comparison of Elemental Anomalies Following Implantation of Different Cell Lines of Glioblastoma Multiforme in the Rat Brain: A Total Reflection X-ray Fluorescence Spectroscopy Study.
    ACS chemical neuroscience, 2020, 12-16, Volume: 11, Issue:24

    Topics: Animals; Brain; Brain Neoplasms; Cell Line, Tumor; Glioblastoma; Humans; Rats; Spectrometry, X-Ray E

2020
Comparison of Elemental Anomalies Following Implantation of Different Cell Lines of Glioblastoma Multiforme in the Rat Brain: A Total Reflection X-ray Fluorescence Spectroscopy Study.
    ACS chemical neuroscience, 2020, 12-16, Volume: 11, Issue:24

    Topics: Animals; Brain; Brain Neoplasms; Cell Line, Tumor; Glioblastoma; Humans; Rats; Spectrometry, X-Ray E

2020
Malignant transformation of a polymorphous low grade neuroepithelial tumor of the young (PLNTY).
    Acta neuropathologica, 2021, Volume: 141, Issue:1

    Topics: Adolescent; Antineoplastic Agents, Alkylating; Brain Edema; Brain Neoplasms; Chemoradiotherapy; Fema

2021
Malignant transformation of a polymorphous low grade neuroepithelial tumor of the young (PLNTY).
    Acta neuropathologica, 2021, Volume: 141, Issue:1

    Topics: Adolescent; Antineoplastic Agents, Alkylating; Brain Edema; Brain Neoplasms; Chemoradiotherapy; Fema

2021
Malignant transformation of a polymorphous low grade neuroepithelial tumor of the young (PLNTY).
    Acta neuropathologica, 2021, Volume: 141, Issue:1

    Topics: Adolescent; Antineoplastic Agents, Alkylating; Brain Edema; Brain Neoplasms; Chemoradiotherapy; Fema

2021
Notable response of a young adult with recurrent glioblastoma multiforme to vincristine-irinotecan-temozolomide and bevacizumab.
    Anti-cancer drugs, 2021, 03-01, Volume: 32, Issue:3

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Brain Neoplasms; Disease-Free Su

2021
Notable response of a young adult with recurrent glioblastoma multiforme to vincristine-irinotecan-temozolomide and bevacizumab.
    Anti-cancer drugs, 2021, 03-01, Volume: 32, Issue:3

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Brain Neoplasms; Disease-Free Su

2021
Notable response of a young adult with recurrent glioblastoma multiforme to vincristine-irinotecan-temozolomide and bevacizumab.
    Anti-cancer drugs, 2021, 03-01, Volume: 32, Issue:3

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Brain Neoplasms; Disease-Free Su

2021
Anti-PD-1 Immunotherapy in Preclinical GL261 Glioblastoma: Influence of Therapeutic Parameters and Non-Invasive Response Biomarker Assessment with MRSI-Based Approaches.
    International journal of molecular sciences, 2020, Nov-20, Volume: 21, Issue:22

    Topics: Animals; Antibodies, Monoclonal; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Immunolog

2020
Anti-PD-1 Immunotherapy in Preclinical GL261 Glioblastoma: Influence of Therapeutic Parameters and Non-Invasive Response Biomarker Assessment with MRSI-Based Approaches.
    International journal of molecular sciences, 2020, Nov-20, Volume: 21, Issue:22

    Topics: Animals; Antibodies, Monoclonal; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Immunolog

2020
Anti-PD-1 Immunotherapy in Preclinical GL261 Glioblastoma: Influence of Therapeutic Parameters and Non-Invasive Response Biomarker Assessment with MRSI-Based Approaches.
    International journal of molecular sciences, 2020, Nov-20, Volume: 21, Issue:22

    Topics: Animals; Antibodies, Monoclonal; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Immunolog

2020
FDG PET/CT in Recurrent Glioblastoma Multiforme With Leptomeningeal and Diffuse Spinal Cord Metastasis.
    Clinical nuclear medicine, 2021, Feb-01, Volume: 46, Issue:2

    Topics: Adult; Brain Neoplasms; Female; Fluorodeoxyglucose F18; Glioblastoma; Humans; Meningeal Neoplasms; P

2021
FDG PET/CT in Recurrent Glioblastoma Multiforme With Leptomeningeal and Diffuse Spinal Cord Metastasis.
    Clinical nuclear medicine, 2021, Feb-01, Volume: 46, Issue:2

    Topics: Adult; Brain Neoplasms; Female; Fluorodeoxyglucose F18; Glioblastoma; Humans; Meningeal Neoplasms; P

2021
FDG PET/CT in Recurrent Glioblastoma Multiforme With Leptomeningeal and Diffuse Spinal Cord Metastasis.
    Clinical nuclear medicine, 2021, Feb-01, Volume: 46, Issue:2

    Topics: Adult; Brain Neoplasms; Female; Fluorodeoxyglucose F18; Glioblastoma; Humans; Meningeal Neoplasms; P

2021
Determination of the cutoff point of the absolute value of MGMTmRNA for predicting the therapeutic resistance to temozolomide in glioblastoma.
    Journal of neurosurgical sciences, 2020, Volume: 64, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; DNA Methylation; Drug Resistance, N

2020
Determination of the cutoff point of the absolute value of MGMTmRNA for predicting the therapeutic resistance to temozolomide in glioblastoma.
    Journal of neurosurgical sciences, 2020, Volume: 64, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; DNA Methylation; Drug Resistance, N

2020
Determination of the cutoff point of the absolute value of MGMTmRNA for predicting the therapeutic resistance to temozolomide in glioblastoma.
    Journal of neurosurgical sciences, 2020, Volume: 64, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; DNA Methylation; Drug Resistance, N

2020
Flunarizine, a drug approved for treating migraine and vertigo, exhibits cytotoxicity in GBM cells.
    European journal of pharmacology, 2021, Feb-05, Volume: 892

    Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Apoptosis Regulato

2021
Flunarizine, a drug approved for treating migraine and vertigo, exhibits cytotoxicity in GBM cells.
    European journal of pharmacology, 2021, Feb-05, Volume: 892

    Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Apoptosis Regulato

2021
Flunarizine, a drug approved for treating migraine and vertigo, exhibits cytotoxicity in GBM cells.
    European journal of pharmacology, 2021, Feb-05, Volume: 892

    Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Apoptosis Regulato

2021
Revealing Temozolomide Resistance Mechanisms via Genome-Wide CRISPR Libraries.
    Cells, 2020, 12-01, Volume: 9, Issue:12

    Topics: Brain Neoplasms; Cell Line, Tumor; Cell Survival; Clustered Regularly Interspaced Short Palindromic

2020
Revealing Temozolomide Resistance Mechanisms via Genome-Wide CRISPR Libraries.
    Cells, 2020, 12-01, Volume: 9, Issue:12

    Topics: Brain Neoplasms; Cell Line, Tumor; Cell Survival; Clustered Regularly Interspaced Short Palindromic

2020
Revealing Temozolomide Resistance Mechanisms via Genome-Wide CRISPR Libraries.
    Cells, 2020, 12-01, Volume: 9, Issue:12

    Topics: Brain Neoplasms; Cell Line, Tumor; Cell Survival; Clustered Regularly Interspaced Short Palindromic

2020
Glioma and temozolomide induced alterations in gut microbiome.
    Scientific reports, 2020, 12-03, Volume: 10, Issue:1

    Topics: Adolescent; Adult; Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dysbiosis; Female; G

2020
Glioma and temozolomide induced alterations in gut microbiome.
    Scientific reports, 2020, 12-03, Volume: 10, Issue:1

    Topics: Adolescent; Adult; Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dysbiosis; Female; G

2020
Glioma and temozolomide induced alterations in gut microbiome.
    Scientific reports, 2020, 12-03, Volume: 10, Issue:1

    Topics: Adolescent; Adult; Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dysbiosis; Female; G

2020
The epidermal growth factor receptor variant type III mutation frequently found in gliomas induces astrogenesis in human cerebral organoids.
    Cell proliferation, 2021, Volume: 54, Issue:2

    Topics: Apoptosis; Astrocytes; Brain; Brain Neoplasms; Cell Differentiation; Cell Line; Cell Proliferation;

2021
The epidermal growth factor receptor variant type III mutation frequently found in gliomas induces astrogenesis in human cerebral organoids.
    Cell proliferation, 2021, Volume: 54, Issue:2

    Topics: Apoptosis; Astrocytes; Brain; Brain Neoplasms; Cell Differentiation; Cell Line; Cell Proliferation;

2021
The epidermal growth factor receptor variant type III mutation frequently found in gliomas induces astrogenesis in human cerebral organoids.
    Cell proliferation, 2021, Volume: 54, Issue:2

    Topics: Apoptosis; Astrocytes; Brain; Brain Neoplasms; Cell Differentiation; Cell Line; Cell Proliferation;

2021
Radiotherapy, Temozolomide, and Antiprogrammed Cell Death Protein 1 Treatments Modulate the Immune Microenvironment in Experimental High-Grade Glioma.
    Neurosurgery, 2021, 01-13, Volume: 88, Issue:2

    Topics: Animals; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Immunological; Brain Neoplasms; C

2021
Radiotherapy, Temozolomide, and Antiprogrammed Cell Death Protein 1 Treatments Modulate the Immune Microenvironment in Experimental High-Grade Glioma.
    Neurosurgery, 2021, 01-13, Volume: 88, Issue:2

    Topics: Animals; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Immunological; Brain Neoplasms; C

2021
Radiotherapy, Temozolomide, and Antiprogrammed Cell Death Protein 1 Treatments Modulate the Immune Microenvironment in Experimental High-Grade Glioma.
    Neurosurgery, 2021, 01-13, Volume: 88, Issue:2

    Topics: Animals; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Immunological; Brain Neoplasms; C

2021
Post-treatment hypermutation in a recurrent diffuse glioma with H3.3 p.G34 Mutation.
    Neuropathology and applied neurobiology, 2021, Volume: 47, Issue:3

    Topics: Adolescent; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy, Adjuvant; Drug Re

2021
Post-treatment hypermutation in a recurrent diffuse glioma with H3.3 p.G34 Mutation.
    Neuropathology and applied neurobiology, 2021, Volume: 47, Issue:3

    Topics: Adolescent; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy, Adjuvant; Drug Re

2021
Post-treatment hypermutation in a recurrent diffuse glioma with H3.3 p.G34 Mutation.
    Neuropathology and applied neurobiology, 2021, Volume: 47, Issue:3

    Topics: Adolescent; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy, Adjuvant; Drug Re

2021
Drug repurposing using transcriptome sequencing and virtual drug screening in a patient with glioblastoma.
    Investigational new drugs, 2021, Volume: 39, Issue:3

    Topics: Aged; Anthracyclines; Antineoplastic Agents; Brain Neoplasms; Cell Line, Tumor; Class Ia Phosphatidy

2021
Drug repurposing using transcriptome sequencing and virtual drug screening in a patient with glioblastoma.
    Investigational new drugs, 2021, Volume: 39, Issue:3

    Topics: Aged; Anthracyclines; Antineoplastic Agents; Brain Neoplasms; Cell Line, Tumor; Class Ia Phosphatidy

2021
Drug repurposing using transcriptome sequencing and virtual drug screening in a patient with glioblastoma.
    Investigational new drugs, 2021, Volume: 39, Issue:3

    Topics: Aged; Anthracyclines; Antineoplastic Agents; Brain Neoplasms; Cell Line, Tumor; Class Ia Phosphatidy

2021
Circ_0005198 enhances temozolomide resistance of glioma cells through miR-198/TRIM14 axis.
    Aging, 2020, 12-09, Volume: 13, Issue:2

    Topics: Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation;

2020
Circ_0005198 enhances temozolomide resistance of glioma cells through miR-198/TRIM14 axis.
    Aging, 2020, 12-09, Volume: 13, Issue:2

    Topics: Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation;

2020
Circ_0005198 enhances temozolomide resistance of glioma cells through miR-198/TRIM14 axis.
    Aging, 2020, 12-09, Volume: 13, Issue:2

    Topics: Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation;

2020
Treatment patterns and outcomes for cerebellar glioblastoma in the concomitant chemoradiation era: A National Cancer database study.
    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2020, Volume: 82, Issue:Pt A

    Topics: Adult; Aged; Brain Neoplasms; Chemoradiotherapy, Adjuvant; Chemotherapy, Adjuvant; Combined Modality

2020
Treatment patterns and outcomes for cerebellar glioblastoma in the concomitant chemoradiation era: A National Cancer database study.
    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2020, Volume: 82, Issue:Pt A

    Topics: Adult; Aged; Brain Neoplasms; Chemoradiotherapy, Adjuvant; Chemotherapy, Adjuvant; Combined Modality

2020
Treatment patterns and outcomes for cerebellar glioblastoma in the concomitant chemoradiation era: A National Cancer database study.
    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2020, Volume: 82, Issue:Pt A

    Topics: Adult; Aged; Brain Neoplasms; Chemoradiotherapy, Adjuvant; Chemotherapy, Adjuvant; Combined Modality

2020
Local and systemic therapy of recurrent ependymoma in children and adolescents: short- and long-term results of the E-HIT-REZ 2005 study.
    Neuro-oncology, 2021, 06-01, Volume: 23, Issue:6

    Topics: Adolescent; Brain Neoplasms; Child; Ependymoma; Humans; Neoplasm Recurrence, Local; Radiotherapy, Ad

2021
Local and systemic therapy of recurrent ependymoma in children and adolescents: short- and long-term results of the E-HIT-REZ 2005 study.
    Neuro-oncology, 2021, 06-01, Volume: 23, Issue:6

    Topics: Adolescent; Brain Neoplasms; Child; Ependymoma; Humans; Neoplasm Recurrence, Local; Radiotherapy, Ad

2021
Local and systemic therapy of recurrent ependymoma in children and adolescents: short- and long-term results of the E-HIT-REZ 2005 study.
    Neuro-oncology, 2021, 06-01, Volume: 23, Issue:6

    Topics: Adolescent; Brain Neoplasms; Child; Ependymoma; Humans; Neoplasm Recurrence, Local; Radiotherapy, Ad

2021
Regorafenib in glioblastoma recurrence: A case report.
    Cancer treatment and research communications, 2021, Volume: 26

    Topics: Brain Neoplasms; Chemoradiotherapy, Adjuvant; Glioblastoma; Humans; Magnetic Resonance Imaging; Male

2021
Regorafenib in glioblastoma recurrence: A case report.
    Cancer treatment and research communications, 2021, Volume: 26

    Topics: Brain Neoplasms; Chemoradiotherapy, Adjuvant; Glioblastoma; Humans; Magnetic Resonance Imaging; Male

2021
Regorafenib in glioblastoma recurrence: A case report.
    Cancer treatment and research communications, 2021, Volume: 26

    Topics: Brain Neoplasms; Chemoradiotherapy, Adjuvant; Glioblastoma; Humans; Magnetic Resonance Imaging; Male

2021
Complete response of radioresistant brain metastases from non-small cell lung cancer with temozolomide: A case report and literature review.
    Medicine, 2020, Dec-18, Volume: 99, Issue:51

    Topics: Adenocarcinoma of Lung; Antineoplastic Agents, Alkylating; Brain Neoplasms; Female; Humans; Lung Neo

2020
Complete response of radioresistant brain metastases from non-small cell lung cancer with temozolomide: A case report and literature review.
    Medicine, 2020, Dec-18, Volume: 99, Issue:51

    Topics: Adenocarcinoma of Lung; Antineoplastic Agents, Alkylating; Brain Neoplasms; Female; Humans; Lung Neo

2020
Complete response of radioresistant brain metastases from non-small cell lung cancer with temozolomide: A case report and literature review.
    Medicine, 2020, Dec-18, Volume: 99, Issue:51

    Topics: Adenocarcinoma of Lung; Antineoplastic Agents, Alkylating; Brain Neoplasms; Female; Humans; Lung Neo

2020
Final Results of the Prospective Biomarker Trial PETra: [
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2021, 03-01, Volume: 27, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Biomarkers, Tumor; Brain Neoplasm

2021
Final Results of the Prospective Biomarker Trial PETra: [
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2021, 03-01, Volume: 27, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Biomarkers, Tumor; Brain Neoplasm

2021
Final Results of the Prospective Biomarker Trial PETra: [
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2021, 03-01, Volume: 27, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Biomarkers, Tumor; Brain Neoplasm

2021
Evaluating survival in subjects with astrocytic brain tumors by dynamic susceptibility-weighted perfusion MR imaging.
    PloS one, 2021, Volume: 16, Issue:1

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Astrocytoma; Brain Ma

2021
Evaluating survival in subjects with astrocytic brain tumors by dynamic susceptibility-weighted perfusion MR imaging.
    PloS one, 2021, Volume: 16, Issue:1

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Astrocytoma; Brain Ma

2021
Evaluating survival in subjects with astrocytic brain tumors by dynamic susceptibility-weighted perfusion MR imaging.
    PloS one, 2021, Volume: 16, Issue:1

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Astrocytoma; Brain Ma

2021
Extracellular vesicles derived from hypoxic glioma stem-like cells confer temozolomide resistance on glioblastoma by delivering miR-30b-3p.
    Theranostics, 2021, Volume: 11, Issue:4

    Topics: Animals; Antineoplastic Agents, Alkylating; Apoptosis; Biomarkers, Tumor; Brain Neoplasms; Cell Prol

2021
Extracellular vesicles derived from hypoxic glioma stem-like cells confer temozolomide resistance on glioblastoma by delivering miR-30b-3p.
    Theranostics, 2021, Volume: 11, Issue:4

    Topics: Animals; Antineoplastic Agents, Alkylating; Apoptosis; Biomarkers, Tumor; Brain Neoplasms; Cell Prol

2021
Extracellular vesicles derived from hypoxic glioma stem-like cells confer temozolomide resistance on glioblastoma by delivering miR-30b-3p.
    Theranostics, 2021, Volume: 11, Issue:4

    Topics: Animals; Antineoplastic Agents, Alkylating; Apoptosis; Biomarkers, Tumor; Brain Neoplasms; Cell Prol

2021
Guanabenz Sensitizes Glioblastoma Cells to Sunitinib by Inhibiting GADD34-Mediated Autophagic Signaling.
    Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics, 2021, Volume: 18, Issue:2

    Topics: Adrenergic alpha-2 Receptor Agonists; Animals; Antineoplastic Agents, Alkylating; Autophagy; Brain N

2021
Guanabenz Sensitizes Glioblastoma Cells to Sunitinib by Inhibiting GADD34-Mediated Autophagic Signaling.
    Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics, 2021, Volume: 18, Issue:2

    Topics: Adrenergic alpha-2 Receptor Agonists; Animals; Antineoplastic Agents, Alkylating; Autophagy; Brain N

2021
Guanabenz Sensitizes Glioblastoma Cells to Sunitinib by Inhibiting GADD34-Mediated Autophagic Signaling.
    Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics, 2021, Volume: 18, Issue:2

    Topics: Adrenergic alpha-2 Receptor Agonists; Animals; Antineoplastic Agents, Alkylating; Autophagy; Brain N

2021
Intranasal Delivery of Temozolomide-Conjugated Gold Nanoparticles Functionalized with Anti-EphA3 for Glioblastoma Targeting.
    Molecular pharmaceutics, 2021, 03-01, Volume: 18, Issue:3

    Topics: Administration, Intranasal; Animals; Apoptosis; Brain Neoplasms; Cell Line; Cell Line, Tumor; Drug R

2021
Intranasal Delivery of Temozolomide-Conjugated Gold Nanoparticles Functionalized with Anti-EphA3 for Glioblastoma Targeting.
    Molecular pharmaceutics, 2021, 03-01, Volume: 18, Issue:3

    Topics: Administration, Intranasal; Animals; Apoptosis; Brain Neoplasms; Cell Line; Cell Line, Tumor; Drug R

2021
Intranasal Delivery of Temozolomide-Conjugated Gold Nanoparticles Functionalized with Anti-EphA3 for Glioblastoma Targeting.
    Molecular pharmaceutics, 2021, 03-01, Volume: 18, Issue:3

    Topics: Administration, Intranasal; Animals; Apoptosis; Brain Neoplasms; Cell Line; Cell Line, Tumor; Drug R

2021
Desquamative skin rash associated with temozolomide in a patient with glioblastoma.
    Dermatologic therapy, 2021, Volume: 34, Issue:2

    Topics: Brain Neoplasms; Dacarbazine; Exanthema; Glioblastoma; Humans; Temozolomide

2021
Desquamative skin rash associated with temozolomide in a patient with glioblastoma.
    Dermatologic therapy, 2021, Volume: 34, Issue:2

    Topics: Brain Neoplasms; Dacarbazine; Exanthema; Glioblastoma; Humans; Temozolomide

2021
Desquamative skin rash associated with temozolomide in a patient with glioblastoma.
    Dermatologic therapy, 2021, Volume: 34, Issue:2

    Topics: Brain Neoplasms; Dacarbazine; Exanthema; Glioblastoma; Humans; Temozolomide

2021
Combinatorial Therapeutic Effect of Inhibitors of Aldehyde Dehydrogenase and Mitochondrial Complex I, and the Chemotherapeutic Drug, Temozolomide against Glioblastoma Tumorspheres.
    Molecules (Basel, Switzerland), 2021, Jan-08, Volume: 26, Issue:2

    Topics: Aldehyde Dehydrogenase; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Electron Tr

2021
Combinatorial Therapeutic Effect of Inhibitors of Aldehyde Dehydrogenase and Mitochondrial Complex I, and the Chemotherapeutic Drug, Temozolomide against Glioblastoma Tumorspheres.
    Molecules (Basel, Switzerland), 2021, Jan-08, Volume: 26, Issue:2

    Topics: Aldehyde Dehydrogenase; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Electron Tr

2021
Combinatorial Therapeutic Effect of Inhibitors of Aldehyde Dehydrogenase and Mitochondrial Complex I, and the Chemotherapeutic Drug, Temozolomide against Glioblastoma Tumorspheres.
    Molecules (Basel, Switzerland), 2021, Jan-08, Volume: 26, Issue:2

    Topics: Aldehyde Dehydrogenase; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Electron Tr

2021
Gene Therapy for Drug-Resistant Glioblastoma via Lipid-Polymer Hybrid Nanoparticles Combined with Focused Ultrasound.
    International journal of nanomedicine, 2021, Volume: 16

    Topics: Animals; Blood-Brain Barrier; Brain Neoplasms; Cell Line, Tumor; Deoxyribonuclease I; Drug Resistanc

2021
Gene Therapy for Drug-Resistant Glioblastoma via Lipid-Polymer Hybrid Nanoparticles Combined with Focused Ultrasound.
    International journal of nanomedicine, 2021, Volume: 16

    Topics: Animals; Blood-Brain Barrier; Brain Neoplasms; Cell Line, Tumor; Deoxyribonuclease I; Drug Resistanc

2021
Gene Therapy for Drug-Resistant Glioblastoma via Lipid-Polymer Hybrid Nanoparticles Combined with Focused Ultrasound.
    International journal of nanomedicine, 2021, Volume: 16

    Topics: Animals; Blood-Brain Barrier; Brain Neoplasms; Cell Line, Tumor; Deoxyribonuclease I; Drug Resistanc

2021
Regulation of temozolomide resistance in glioma cells via the RIP2/NF-κB/MGMT pathway.
    CNS neuroscience & therapeutics, 2021, Volume: 27, Issue:5

    Topics: Animals; Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cell Line, Tumor; DNA Modifi

2021
Regulation of temozolomide resistance in glioma cells via the RIP2/NF-κB/MGMT pathway.
    CNS neuroscience & therapeutics, 2021, Volume: 27, Issue:5

    Topics: Animals; Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cell Line, Tumor; DNA Modifi

2021
Regulation of temozolomide resistance in glioma cells via the RIP2/NF-κB/MGMT pathway.
    CNS neuroscience & therapeutics, 2021, Volume: 27, Issue:5

    Topics: Animals; Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cell Line, Tumor; DNA Modifi

2021
The Role of Temozolomide in Patients With Newly Diagnosed Wild-Type IDH, Unmethylated MGMTp Glioblastoma During the COVID-19 Pandemic.
    JAMA oncology, 2021, 05-01, Volume: 7, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Chemotherapy, Adjuvant; COVID

2021
The Role of Temozolomide in Patients With Newly Diagnosed Wild-Type IDH, Unmethylated MGMTp Glioblastoma During the COVID-19 Pandemic.
    JAMA oncology, 2021, 05-01, Volume: 7, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Chemotherapy, Adjuvant; COVID

2021
The Role of Temozolomide in Patients With Newly Diagnosed Wild-Type IDH, Unmethylated MGMTp Glioblastoma During the COVID-19 Pandemic.
    JAMA oncology, 2021, 05-01, Volume: 7, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Chemotherapy, Adjuvant; COVID

2021
Timing of Chemoradiation in Newly Diagnosed Glioblastoma: Comparative Analysis Between County and Managed Care Health Care Models.
    World neurosurgery, 2021, Volume: 149

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Combined Modalit

2021
Timing of Chemoradiation in Newly Diagnosed Glioblastoma: Comparative Analysis Between County and Managed Care Health Care Models.
    World neurosurgery, 2021, Volume: 149

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Combined Modalit

2021
Timing of Chemoradiation in Newly Diagnosed Glioblastoma: Comparative Analysis Between County and Managed Care Health Care Models.
    World neurosurgery, 2021, Volume: 149

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Combined Modalit

2021
Molecular biological investigation of temozolomide and KC7F2 combination in U87MG glioma cell line.
    Gene, 2021, Apr-15, Volume: 776

    Topics: Antineoplastic Agents; Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cell Line, Tum

2021
Molecular biological investigation of temozolomide and KC7F2 combination in U87MG glioma cell line.
    Gene, 2021, Apr-15, Volume: 776

    Topics: Antineoplastic Agents; Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cell Line, Tum

2021
Molecular biological investigation of temozolomide and KC7F2 combination in U87MG glioma cell line.
    Gene, 2021, Apr-15, Volume: 776

    Topics: Antineoplastic Agents; Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cell Line, Tum

2021
High prevalence of clonal hematopoiesis-type genomic abnormalities in cell-free DNA in invasive gliomas after treatment.
    International journal of cancer, 2021, 06-01, Volume: 148, Issue:11

    Topics: Adult; Aged; Aged, 80 and over; Brain Neoplasms; Cell-Free Nucleic Acids; Chemoradiotherapy; Clonal

2021
High prevalence of clonal hematopoiesis-type genomic abnormalities in cell-free DNA in invasive gliomas after treatment.
    International journal of cancer, 2021, 06-01, Volume: 148, Issue:11

    Topics: Adult; Aged; Aged, 80 and over; Brain Neoplasms; Cell-Free Nucleic Acids; Chemoradiotherapy; Clonal

2021
High prevalence of clonal hematopoiesis-type genomic abnormalities in cell-free DNA in invasive gliomas after treatment.
    International journal of cancer, 2021, 06-01, Volume: 148, Issue:11

    Topics: Adult; Aged; Aged, 80 and over; Brain Neoplasms; Cell-Free Nucleic Acids; Chemoradiotherapy; Clonal

2021
Long-Term Near-Infrared Signal Tracking of the Therapeutic Changes of Glioblastoma Cells in Brain Tissue with Ultrasound-Guided Persistent Luminescent Nanocomposites.
    ACS applied materials & interfaces, 2021, Feb-10, Volume: 13, Issue:5

    Topics: Animals; Antineoplastic Agents, Alkylating; Blood-Brain Barrier; Brain Neoplasms; Cell Line, Tumor;

2021
Long-Term Near-Infrared Signal Tracking of the Therapeutic Changes of Glioblastoma Cells in Brain Tissue with Ultrasound-Guided Persistent Luminescent Nanocomposites.
    ACS applied materials & interfaces, 2021, Feb-10, Volume: 13, Issue:5

    Topics: Animals; Antineoplastic Agents, Alkylating; Blood-Brain Barrier; Brain Neoplasms; Cell Line, Tumor;

2021
Long-Term Near-Infrared Signal Tracking of the Therapeutic Changes of Glioblastoma Cells in Brain Tissue with Ultrasound-Guided Persistent Luminescent Nanocomposites.
    ACS applied materials & interfaces, 2021, Feb-10, Volume: 13, Issue:5

    Topics: Animals; Antineoplastic Agents, Alkylating; Blood-Brain Barrier; Brain Neoplasms; Cell Line, Tumor;

2021
The NRG3/ERBB4 signaling cascade as a novel therapeutic target for canine glioma.
    Experimental cell research, 2021, 03-15, Volume: 400, Issue:2

    Topics: Afatinib; Animals; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Dog Diseases; Do

2021
The NRG3/ERBB4 signaling cascade as a novel therapeutic target for canine glioma.
    Experimental cell research, 2021, 03-15, Volume: 400, Issue:2

    Topics: Afatinib; Animals; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Dog Diseases; Do

2021
The NRG3/ERBB4 signaling cascade as a novel therapeutic target for canine glioma.
    Experimental cell research, 2021, 03-15, Volume: 400, Issue:2

    Topics: Afatinib; Animals; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Dog Diseases; Do

2021
Inhibition of mitochondrial carrier homolog 2 (MTCH2) suppresses tumor invasion and enhances sensitivity to temozolomide in malignant glioma.
    Molecular medicine (Cambridge, Mass.), 2021, 01-28, Volume: 27, Issue:1

    Topics: Animals; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cell Movement; Drug Resistance, Neoplasm; Gen

2021
Inhibition of mitochondrial carrier homolog 2 (MTCH2) suppresses tumor invasion and enhances sensitivity to temozolomide in malignant glioma.
    Molecular medicine (Cambridge, Mass.), 2021, 01-28, Volume: 27, Issue:1

    Topics: Animals; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cell Movement; Drug Resistance, Neoplasm; Gen

2021
Inhibition of mitochondrial carrier homolog 2 (MTCH2) suppresses tumor invasion and enhances sensitivity to temozolomide in malignant glioma.
    Molecular medicine (Cambridge, Mass.), 2021, 01-28, Volume: 27, Issue:1

    Topics: Animals; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cell Movement; Drug Resistance, Neoplasm; Gen

2021
[Establishment of a mouse model bearing orthotopic temozolomide-resistant glioma].
    Nan fang yi ke da xue xue bao = Journal of Southern Medical University, 2021, Jan-30, Volume: 41, Issue:1

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Disease Models, Anima

2021
[Establishment of a mouse model bearing orthotopic temozolomide-resistant glioma].
    Nan fang yi ke da xue xue bao = Journal of Southern Medical University, 2021, Jan-30, Volume: 41, Issue:1

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Disease Models, Anima

2021
[Establishment of a mouse model bearing orthotopic temozolomide-resistant glioma].
    Nan fang yi ke da xue xue bao = Journal of Southern Medical University, 2021, Jan-30, Volume: 41, Issue:1

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Disease Models, Anima

2021
Synergistic therapeutic benefit by combining the antibody drug conjugate, depatux-m with temozolomide in pre-clinical models of glioblastoma with overexpression of EGFR.
    Journal of neuro-oncology, 2021, Volume: 152, Issue:2

    Topics: Animals; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Brain Ne

2021
Synergistic therapeutic benefit by combining the antibody drug conjugate, depatux-m with temozolomide in pre-clinical models of glioblastoma with overexpression of EGFR.
    Journal of neuro-oncology, 2021, Volume: 152, Issue:2

    Topics: Animals; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Brain Ne

2021
Synergistic therapeutic benefit by combining the antibody drug conjugate, depatux-m with temozolomide in pre-clinical models of glioblastoma with overexpression of EGFR.
    Journal of neuro-oncology, 2021, Volume: 152, Issue:2

    Topics: Animals; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Brain Ne

2021
Radiotherapy Plus Procarbazine, Lomustine, and Vincristine Versus Radiotherapy Plus Temozolomide for IDH-Mutant Anaplastic Astrocytoma: A Retrospective Multicenter Analysis of the French POLA Cohort.
    The oncologist, 2021, Volume: 26, Issue:5

    Topics: Antineoplastic Combined Chemotherapy Protocols; Astrocytoma; Brain Neoplasms; Humans; Lomustine; Pro

2021
Radiotherapy Plus Procarbazine, Lomustine, and Vincristine Versus Radiotherapy Plus Temozolomide for IDH-Mutant Anaplastic Astrocytoma: A Retrospective Multicenter Analysis of the French POLA Cohort.
    The oncologist, 2021, Volume: 26, Issue:5

    Topics: Antineoplastic Combined Chemotherapy Protocols; Astrocytoma; Brain Neoplasms; Humans; Lomustine; Pro

2021
Radiotherapy Plus Procarbazine, Lomustine, and Vincristine Versus Radiotherapy Plus Temozolomide for IDH-Mutant Anaplastic Astrocytoma: A Retrospective Multicenter Analysis of the French POLA Cohort.
    The oncologist, 2021, Volume: 26, Issue:5

    Topics: Antineoplastic Combined Chemotherapy Protocols; Astrocytoma; Brain Neoplasms; Humans; Lomustine; Pro

2021
A 25-year retrospective, single center analysis of 343 WHO grade II/III glioma patients: implications for grading and temozolomide therapy.
    Journal of cancer research and clinical oncology, 2021, Volume: 147, Issue:8

    Topics: Adult; Aged; Aged, 80 and over; Brain Neoplasms; Female; Germany; Glioma; Humans; Isocitrate Dehydro

2021
A 25-year retrospective, single center analysis of 343 WHO grade II/III glioma patients: implications for grading and temozolomide therapy.
    Journal of cancer research and clinical oncology, 2021, Volume: 147, Issue:8

    Topics: Adult; Aged; Aged, 80 and over; Brain Neoplasms; Female; Germany; Glioma; Humans; Isocitrate Dehydro

2021
A 25-year retrospective, single center analysis of 343 WHO grade II/III glioma patients: implications for grading and temozolomide therapy.
    Journal of cancer research and clinical oncology, 2021, Volume: 147, Issue:8

    Topics: Adult; Aged; Aged, 80 and over; Brain Neoplasms; Female; Germany; Glioma; Humans; Isocitrate Dehydro

2021
A neuro evolutionary algorithm for patient calibrated prediction of survival in Glioblastoma patients.
    Journal of biomedical informatics, 2021, Volume: 115

    Topics: Algorithms; Antineoplastic Agents, Alkylating; Brain Neoplasms; Glioblastoma; Humans; Temozolomide

2021
A neuro evolutionary algorithm for patient calibrated prediction of survival in Glioblastoma patients.
    Journal of biomedical informatics, 2021, Volume: 115

    Topics: Algorithms; Antineoplastic Agents, Alkylating; Brain Neoplasms; Glioblastoma; Humans; Temozolomide

2021
A neuro evolutionary algorithm for patient calibrated prediction of survival in Glioblastoma patients.
    Journal of biomedical informatics, 2021, Volume: 115

    Topics: Algorithms; Antineoplastic Agents, Alkylating; Brain Neoplasms; Glioblastoma; Humans; Temozolomide

2021
Early results from the CODEL trial for anaplastic oligodendrogliomas: is temozolomide futile?
    Neuro-oncology, 2021, 03-25, Volume: 23, Issue:3

    Topics: Brain Neoplasms; Dacarbazine; Humans; Oligodendroglioma; Temozolomide

2021
Early results from the CODEL trial for anaplastic oligodendrogliomas: is temozolomide futile?
    Neuro-oncology, 2021, 03-25, Volume: 23, Issue:3

    Topics: Brain Neoplasms; Dacarbazine; Humans; Oligodendroglioma; Temozolomide

2021
Early results from the CODEL trial for anaplastic oligodendrogliomas: is temozolomide futile?
    Neuro-oncology, 2021, 03-25, Volume: 23, Issue:3

    Topics: Brain Neoplasms; Dacarbazine; Humans; Oligodendroglioma; Temozolomide

2021
Bioresorbable, electrospun nonwoven for delayed and prolonged release of temozolomide and nimorazole.
    European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 2021, Volume: 161

    Topics: Absorbable Implants; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemistry, Pharmaceutical;

2021
Bioresorbable, electrospun nonwoven for delayed and prolonged release of temozolomide and nimorazole.
    European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 2021, Volume: 161

    Topics: Absorbable Implants; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemistry, Pharmaceutical;

2021
Bioresorbable, electrospun nonwoven for delayed and prolonged release of temozolomide and nimorazole.
    European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 2021, Volume: 161

    Topics: Absorbable Implants; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemistry, Pharmaceutical;

2021
Data-Driven Computational Modeling Identifies Determinants of Glioblastoma Response to SHP2 Inhibition.
    Cancer research, 2021, 04-15, Volume: 81, Issue:8

    Topics: Animals; Brain Neoplasms; Cell Line, Tumor; Data Science; Dimethyl Sulfoxide; DNA Repair; Drug Resis

2021
Data-Driven Computational Modeling Identifies Determinants of Glioblastoma Response to SHP2 Inhibition.
    Cancer research, 2021, 04-15, Volume: 81, Issue:8

    Topics: Animals; Brain Neoplasms; Cell Line, Tumor; Data Science; Dimethyl Sulfoxide; DNA Repair; Drug Resis

2021
Data-Driven Computational Modeling Identifies Determinants of Glioblastoma Response to SHP2 Inhibition.
    Cancer research, 2021, 04-15, Volume: 81, Issue:8

    Topics: Animals; Brain Neoplasms; Cell Line, Tumor; Data Science; Dimethyl Sulfoxide; DNA Repair; Drug Resis

2021
Multicentric non-enhancing lesions in glioblastoma: A retrospective study.
    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2021, Volume: 85

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherap

2021
Multicentric non-enhancing lesions in glioblastoma: A retrospective study.
    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2021, Volume: 85

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherap

2021
Multicentric non-enhancing lesions in glioblastoma: A retrospective study.
    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2021, Volume: 85

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherap

2021
Pharmacogenetics of ATP binding cassette transporter MDR1(1236C>T) gene polymorphism with glioma patients receiving Temozolomide-based chemoradiation therapy in Indian population.
    The pharmacogenomics journal, 2021, Volume: 21, Issue:2

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Asian People; ATP Binding Cassette Transporter, Subf

2021
Pharmacogenetics of ATP binding cassette transporter MDR1(1236C>T) gene polymorphism with glioma patients receiving Temozolomide-based chemoradiation therapy in Indian population.
    The pharmacogenomics journal, 2021, Volume: 21, Issue:2

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Asian People; ATP Binding Cassette Transporter, Subf

2021
Pharmacogenetics of ATP binding cassette transporter MDR1(1236C>T) gene polymorphism with glioma patients receiving Temozolomide-based chemoradiation therapy in Indian population.
    The pharmacogenomics journal, 2021, Volume: 21, Issue:2

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Asian People; ATP Binding Cassette Transporter, Subf

2021
AS602801 sensitizes glioma cells to temozolomide and vincristine by blocking gap junction communication between glioma cells and astrocytes.
    Journal of cellular and molecular medicine, 2021, Volume: 25, Issue:8

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Astrocytes; Benzothiazoles; Brai

2021
AS602801 sensitizes glioma cells to temozolomide and vincristine by blocking gap junction communication between glioma cells and astrocytes.
    Journal of cellular and molecular medicine, 2021, Volume: 25, Issue:8

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Astrocytes; Benzothiazoles; Brai

2021
AS602801 sensitizes glioma cells to temozolomide and vincristine by blocking gap junction communication between glioma cells and astrocytes.
    Journal of cellular and molecular medicine, 2021, Volume: 25, Issue:8

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Astrocytes; Benzothiazoles; Brai

2021
The novel roles of virus infection-associated gene CDKN1A in chemoresistance and immune infiltration of glioblastoma.
    Aging, 2021, 02-17, Volume: 13, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Carcinogenesis; Cell Line, Tumor; Cyclin-Depende

2021
The novel roles of virus infection-associated gene CDKN1A in chemoresistance and immune infiltration of glioblastoma.
    Aging, 2021, 02-17, Volume: 13, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Carcinogenesis; Cell Line, Tumor; Cyclin-Depende

2021
The novel roles of virus infection-associated gene CDKN1A in chemoresistance and immune infiltration of glioblastoma.
    Aging, 2021, 02-17, Volume: 13, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Carcinogenesis; Cell Line, Tumor; Cyclin-Depende

2021
Nicardipine sensitizes temozolomide by inhibiting autophagy and promoting cell apoptosis in glioma stem cells.
    Aging, 2021, 02-17, Volume: 13, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Apoptosis; Autophagy; Brain Neoplasms; Calcium Channel Blockers;

2021
Nicardipine sensitizes temozolomide by inhibiting autophagy and promoting cell apoptosis in glioma stem cells.
    Aging, 2021, 02-17, Volume: 13, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Apoptosis; Autophagy; Brain Neoplasms; Calcium Channel Blockers;

2021
Nicardipine sensitizes temozolomide by inhibiting autophagy and promoting cell apoptosis in glioma stem cells.
    Aging, 2021, 02-17, Volume: 13, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Apoptosis; Autophagy; Brain Neoplasms; Calcium Channel Blockers;

2021
Cannabinoids in glioblastoma multiforme-hype or hope?
    British journal of cancer, 2021, Volume: 124, Issue:8

    Topics: Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Cannabidiol; Cell Proliferation; Ce

2021
Cannabinoids in glioblastoma multiforme-hype or hope?
    British journal of cancer, 2021, Volume: 124, Issue:8

    Topics: Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Cannabidiol; Cell Proliferation; Ce

2021
Cannabinoids in glioblastoma multiforme-hype or hope?
    British journal of cancer, 2021, Volume: 124, Issue:8

    Topics: Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Cannabidiol; Cell Proliferation; Ce

2021
Predictive value of MGMT promoter methylation on the survival of TMZ treated
    Cancer biology & medicine, 2021, 02-15, Volume: 18, Issue:1

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Biomarkers, Tumor; Brain Neoplasms; Cohort Studies;

2021
Predictive value of MGMT promoter methylation on the survival of TMZ treated
    Cancer biology & medicine, 2021, 02-15, Volume: 18, Issue:1

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Biomarkers, Tumor; Brain Neoplasms; Cohort Studies;

2021
Predictive value of MGMT promoter methylation on the survival of TMZ treated
    Cancer biology & medicine, 2021, 02-15, Volume: 18, Issue:1

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Biomarkers, Tumor; Brain Neoplasms; Cohort Studies;

2021
Telomerase reverse transcriptase promoter mutation- and O
    European journal of cancer (Oxford, England : 1990), 2021, Volume: 147

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; DNA Methylation; DNA Modification Methylases; DN

2021
Telomerase reverse transcriptase promoter mutation- and O
    European journal of cancer (Oxford, England : 1990), 2021, Volume: 147

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; DNA Methylation; DNA Modification Methylases; DN

2021
Telomerase reverse transcriptase promoter mutation- and O
    European journal of cancer (Oxford, England : 1990), 2021, Volume: 147

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; DNA Methylation; DNA Modification Methylases; DN

2021
Exosomal connexin 43 regulates the resistance of glioma cells to temozolomide.
    Oncology reports, 2021, Volume: 45, Issue:4

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Cell Movement; Connexin 43; Dr

2021
Exosomal connexin 43 regulates the resistance of glioma cells to temozolomide.
    Oncology reports, 2021, Volume: 45, Issue:4

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Cell Movement; Connexin 43; Dr

2021
Exosomal connexin 43 regulates the resistance of glioma cells to temozolomide.
    Oncology reports, 2021, Volume: 45, Issue:4

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Cell Movement; Connexin 43; Dr

2021
APR-246 combined with 3-deazaneplanocin A, panobinostat or temozolomide reduces clonogenicity and induces apoptosis in glioblastoma cells.
    International journal of oncology, 2021, Volume: 58, Issue:3

    Topics: Adenosine; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Brain Neoplasms; Cell Line, Tu

2021
APR-246 combined with 3-deazaneplanocin A, panobinostat or temozolomide reduces clonogenicity and induces apoptosis in glioblastoma cells.
    International journal of oncology, 2021, Volume: 58, Issue:3

    Topics: Adenosine; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Brain Neoplasms; Cell Line, Tu

2021
APR-246 combined with 3-deazaneplanocin A, panobinostat or temozolomide reduces clonogenicity and induces apoptosis in glioblastoma cells.
    International journal of oncology, 2021, Volume: 58, Issue:3

    Topics: Adenosine; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Brain Neoplasms; Cell Line, Tu

2021
Prognostic value of TP53 expression and MGMT methylation in glioblastoma patients treated with temozolomide combined with other chemotherapies.
    Journal of neuro-oncology, 2021, Volume: 152, Issue:3

    Topics: Antineoplastic Agents; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; DNA Methylat

2021
Prognostic value of TP53 expression and MGMT methylation in glioblastoma patients treated with temozolomide combined with other chemotherapies.
    Journal of neuro-oncology, 2021, Volume: 152, Issue:3

    Topics: Antineoplastic Agents; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; DNA Methylat

2021
Prognostic value of TP53 expression and MGMT methylation in glioblastoma patients treated with temozolomide combined with other chemotherapies.
    Journal of neuro-oncology, 2021, Volume: 152, Issue:3

    Topics: Antineoplastic Agents; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; DNA Methylat

2021
The number of methylated CpG sites within the MGMT promoter region linearly correlates with outcome in glioblastoma receiving alkylating agents.
    Acta neuropathologica communications, 2021, 03-04, Volume: 9, Issue:1

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Base Sequence; Brain

2021
The number of methylated CpG sites within the MGMT promoter region linearly correlates with outcome in glioblastoma receiving alkylating agents.
    Acta neuropathologica communications, 2021, 03-04, Volume: 9, Issue:1

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Base Sequence; Brain

2021
The number of methylated CpG sites within the MGMT promoter region linearly correlates with outcome in glioblastoma receiving alkylating agents.
    Acta neuropathologica communications, 2021, 03-04, Volume: 9, Issue:1

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Base Sequence; Brain

2021
The Paired Siglecs in Brain Tumours Therapy: The Immunomodulatory Effect of Dexamethasone and Temozolomide in Human Glioma In Vitro Model.
    International journal of molecular sciences, 2021, Feb-11, Volume: 22, Issue:4

    Topics: Antigens, CD; Antigens, Differentiation, Myelomonocytic; Antineoplastic Combined Chemotherapy Protoc

2021
The Paired Siglecs in Brain Tumours Therapy: The Immunomodulatory Effect of Dexamethasone and Temozolomide in Human Glioma In Vitro Model.
    International journal of molecular sciences, 2021, Feb-11, Volume: 22, Issue:4

    Topics: Antigens, CD; Antigens, Differentiation, Myelomonocytic; Antineoplastic Combined Chemotherapy Protoc

2021
The Paired Siglecs in Brain Tumours Therapy: The Immunomodulatory Effect of Dexamethasone and Temozolomide in Human Glioma In Vitro Model.
    International journal of molecular sciences, 2021, Feb-11, Volume: 22, Issue:4

    Topics: Antigens, CD; Antigens, Differentiation, Myelomonocytic; Antineoplastic Combined Chemotherapy Protoc

2021
Hsa_circ_0110757 upregulates ITGA1 to facilitate temozolomide resistance in glioma by suppressing hsa-miR-1298-5p.
    Cell death & disease, 2021, 03-05, Volume: 12, Issue:3

    Topics: Animals; Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Drug Resis

2021
Hsa_circ_0110757 upregulates ITGA1 to facilitate temozolomide resistance in glioma by suppressing hsa-miR-1298-5p.
    Cell death & disease, 2021, 03-05, Volume: 12, Issue:3

    Topics: Animals; Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Drug Resis

2021
Hsa_circ_0110757 upregulates ITGA1 to facilitate temozolomide resistance in glioma by suppressing hsa-miR-1298-5p.
    Cell death & disease, 2021, 03-05, Volume: 12, Issue:3

    Topics: Animals; Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Drug Resis

2021
Survival impact of incidental subventricular zone irradiation in IDH-wildtype glioblastoma.
    Acta oncologica (Stockholm, Sweden), 2021, Volume: 60, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Glioblastoma; Humans; Lateral Ventricles; Progno

2021
Survival impact of incidental subventricular zone irradiation in IDH-wildtype glioblastoma.
    Acta oncologica (Stockholm, Sweden), 2021, Volume: 60, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Glioblastoma; Humans; Lateral Ventricles; Progno

2021
Survival impact of incidental subventricular zone irradiation in IDH-wildtype glioblastoma.
    Acta oncologica (Stockholm, Sweden), 2021, Volume: 60, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Glioblastoma; Humans; Lateral Ventricles; Progno

2021
Cognitive outcomes in patients with low-grade glioma.
    Neuro-oncology, 2021, 05-05, Volume: 23, Issue:5

    Topics: Brain Neoplasms; Cognition; Glioma; Humans; Memory; Temozolomide

2021
Cognitive outcomes in patients with low-grade glioma.
    Neuro-oncology, 2021, 05-05, Volume: 23, Issue:5

    Topics: Brain Neoplasms; Cognition; Glioma; Humans; Memory; Temozolomide

2021
Cognitive outcomes in patients with low-grade glioma.
    Neuro-oncology, 2021, 05-05, Volume: 23, Issue:5

    Topics: Brain Neoplasms; Cognition; Glioma; Humans; Memory; Temozolomide

2021
Secondary gliosarcoma: the clinicopathological features and the development of a patient-derived xenograft model of gliosarcoma.
    BMC cancer, 2021, Mar-11, Volume: 21, Issue:1

    Topics: Animals; Biomarkers, Tumor; Brain; Brain Neoplasms; Cell Cycle Proteins; Chemoradiotherapy; Cranioto

2021
Secondary gliosarcoma: the clinicopathological features and the development of a patient-derived xenograft model of gliosarcoma.
    BMC cancer, 2021, Mar-11, Volume: 21, Issue:1

    Topics: Animals; Biomarkers, Tumor; Brain; Brain Neoplasms; Cell Cycle Proteins; Chemoradiotherapy; Cranioto

2021
Secondary gliosarcoma: the clinicopathological features and the development of a patient-derived xenograft model of gliosarcoma.
    BMC cancer, 2021, Mar-11, Volume: 21, Issue:1

    Topics: Animals; Biomarkers, Tumor; Brain; Brain Neoplasms; Cell Cycle Proteins; Chemoradiotherapy; Cranioto

2021
CDK1 is up-regulated by temozolomide in an NF-κB dependent manner in glioblastoma.
    Scientific reports, 2021, 03-11, Volume: 11, Issue:1

    Topics: B-Cell Lymphoma 3 Protein; Base Sequence; Binding Sites; Brain Neoplasms; CDC2 Protein Kinase; Cell

2021
CDK1 is up-regulated by temozolomide in an NF-κB dependent manner in glioblastoma.
    Scientific reports, 2021, 03-11, Volume: 11, Issue:1

    Topics: B-Cell Lymphoma 3 Protein; Base Sequence; Binding Sites; Brain Neoplasms; CDC2 Protein Kinase; Cell

2021
CDK1 is up-regulated by temozolomide in an NF-κB dependent manner in glioblastoma.
    Scientific reports, 2021, 03-11, Volume: 11, Issue:1

    Topics: B-Cell Lymphoma 3 Protein; Base Sequence; Binding Sites; Brain Neoplasms; CDC2 Protein Kinase; Cell

2021
The ALK inhibitors, alectinib and ceritinib, induce ALK-independent and STAT3-dependent glioblastoma cell death.
    Cancer science, 2021, Volume: 112, Issue:6

    Topics: Administration, Oral; Anaplastic Lymphoma Kinase; Animals; Brain Neoplasms; Carbazoles; Cell Line, T

2021
The ALK inhibitors, alectinib and ceritinib, induce ALK-independent and STAT3-dependent glioblastoma cell death.
    Cancer science, 2021, Volume: 112, Issue:6

    Topics: Administration, Oral; Anaplastic Lymphoma Kinase; Animals; Brain Neoplasms; Carbazoles; Cell Line, T

2021
The ALK inhibitors, alectinib and ceritinib, induce ALK-independent and STAT3-dependent glioblastoma cell death.
    Cancer science, 2021, Volume: 112, Issue:6

    Topics: Administration, Oral; Anaplastic Lymphoma Kinase; Animals; Brain Neoplasms; Carbazoles; Cell Line, T

2021
MPPED2 is downregulated in glioblastoma, and its restoration inhibits proliferation and increases the sensitivity to temozolomide of glioblastoma cells.
    Cell cycle (Georgetown, Tex.), 2021, Volume: 20, Issue:7

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Down-Regul

2021
MPPED2 is downregulated in glioblastoma, and its restoration inhibits proliferation and increases the sensitivity to temozolomide of glioblastoma cells.
    Cell cycle (Georgetown, Tex.), 2021, Volume: 20, Issue:7

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Down-Regul

2021
MPPED2 is downregulated in glioblastoma, and its restoration inhibits proliferation and increases the sensitivity to temozolomide of glioblastoma cells.
    Cell cycle (Georgetown, Tex.), 2021, Volume: 20, Issue:7

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Down-Regul

2021
Nidogen-1 expression is associated with overall survival and temozolomide sensitivity in low-grade glioma patients.
    Aging, 2021, 03-18, Volume: 13, Issue:6

    Topics: Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Gene Expression Regulation, Neoplastic; Gliom

2021
Nidogen-1 expression is associated with overall survival and temozolomide sensitivity in low-grade glioma patients.
    Aging, 2021, 03-18, Volume: 13, Issue:6

    Topics: Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Gene Expression Regulation, Neoplastic; Gliom

2021
Nidogen-1 expression is associated with overall survival and temozolomide sensitivity in low-grade glioma patients.
    Aging, 2021, 03-18, Volume: 13, Issue:6

    Topics: Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Gene Expression Regulation, Neoplastic; Gliom

2021
Adjuvant therapeutic potential of moderate hypothermia for glioblastoma.
    Journal of neuro-oncology, 2021, Volume: 152, Issue:3

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant; Glioblastoma; Humans; Hy

2021
Adjuvant therapeutic potential of moderate hypothermia for glioblastoma.
    Journal of neuro-oncology, 2021, Volume: 152, Issue:3

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant; Glioblastoma; Humans; Hy

2021
Adjuvant therapeutic potential of moderate hypothermia for glioblastoma.
    Journal of neuro-oncology, 2021, Volume: 152, Issue:3

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant; Glioblastoma; Humans; Hy

2021
Patterns of glioblastoma treatment and survival over a 16-years period: pooled data from the German Cancer Registries.
    Journal of cancer research and clinical oncology, 2021, Volume: 147, Issue:11

    Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Ne

2021
Patterns of glioblastoma treatment and survival over a 16-years period: pooled data from the German Cancer Registries.
    Journal of cancer research and clinical oncology, 2021, Volume: 147, Issue:11

    Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Ne

2021
Patterns of glioblastoma treatment and survival over a 16-years period: pooled data from the German Cancer Registries.
    Journal of cancer research and clinical oncology, 2021, Volume: 147, Issue:11

    Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Ne

2021
Clinical validation of a novel quantitative assay for the detection of MGMT methylation in glioblastoma patients.
    Clinical epigenetics, 2021, 03-09, Volume: 13, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Biomarkers, Tumor; Brain Neoplasm

2021
Clinical validation of a novel quantitative assay for the detection of MGMT methylation in glioblastoma patients.
    Clinical epigenetics, 2021, 03-09, Volume: 13, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Biomarkers, Tumor; Brain Neoplasm

2021
Clinical validation of a novel quantitative assay for the detection of MGMT methylation in glioblastoma patients.
    Clinical epigenetics, 2021, 03-09, Volume: 13, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Biomarkers, Tumor; Brain Neoplasm

2021
Gene expression-based biomarkers designating glioblastomas resistant to multiple treatment strategies.
    Carcinogenesis, 2021, 06-21, Volume: 42, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Biomarkers, Tumor; Brain Neoplasm

2021
Gene expression-based biomarkers designating glioblastomas resistant to multiple treatment strategies.
    Carcinogenesis, 2021, 06-21, Volume: 42, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Biomarkers, Tumor; Brain Neoplasm

2021
Gene expression-based biomarkers designating glioblastomas resistant to multiple treatment strategies.
    Carcinogenesis, 2021, 06-21, Volume: 42, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Biomarkers, Tumor; Brain Neoplasm

2021
Cancer-specific loss of
    Proceedings of the National Academy of Sciences of the United States of America, 2021, 03-30, Volume: 118, Issue:13

    Topics: Animals; Antineoplastic Agents, Alkylating; Astrocytes; Brain Neoplasms; Cell Line, Tumor; Cell Prol

2021
Cancer-specific loss of
    Proceedings of the National Academy of Sciences of the United States of America, 2021, 03-30, Volume: 118, Issue:13

    Topics: Animals; Antineoplastic Agents, Alkylating; Astrocytes; Brain Neoplasms; Cell Line, Tumor; Cell Prol

2021
Cancer-specific loss of
    Proceedings of the National Academy of Sciences of the United States of America, 2021, 03-30, Volume: 118, Issue:13

    Topics: Animals; Antineoplastic Agents, Alkylating; Astrocytes; Brain Neoplasms; Cell Line, Tumor; Cell Prol

2021
Nanocell-mediated delivery of miR-34a counteracts temozolomide resistance in glioblastoma.
    Molecular medicine (Cambridge, Mass.), 2021, 03-25, Volume: 27, Issue:1

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; D

2021
Nanocell-mediated delivery of miR-34a counteracts temozolomide resistance in glioblastoma.
    Molecular medicine (Cambridge, Mass.), 2021, 03-25, Volume: 27, Issue:1

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; D

2021
Nanocell-mediated delivery of miR-34a counteracts temozolomide resistance in glioblastoma.
    Molecular medicine (Cambridge, Mass.), 2021, 03-25, Volume: 27, Issue:1

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; D

2021
Could upfront temozolomide chemotherapy postpone the need for radiotherapy in young patients with high-risk low-grade gliomas?
    Chinese medical journal, 2021, Mar-25, Volume: 134, Issue:11

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Glioma; Humans; Temozolomide

2021
Could upfront temozolomide chemotherapy postpone the need for radiotherapy in young patients with high-risk low-grade gliomas?
    Chinese medical journal, 2021, Mar-25, Volume: 134, Issue:11

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Glioma; Humans; Temozolomide

2021
Could upfront temozolomide chemotherapy postpone the need for radiotherapy in young patients with high-risk low-grade gliomas?
    Chinese medical journal, 2021, Mar-25, Volume: 134, Issue:11

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Glioma; Humans; Temozolomide

2021
Effects of the Anti-Tumorigenic Agent AT101 on Human Glioblastoma Cells in the Microenvironmental Glioma Stem Cell Niche.
    International journal of molecular sciences, 2021, Mar-30, Volume: 22, Issue:7

    Topics: Antineoplastic Combined Chemotherapy Protocols; Brain; Brain Neoplasms; Carcinogenesis; Cell Line, T

2021
Effects of the Anti-Tumorigenic Agent AT101 on Human Glioblastoma Cells in the Microenvironmental Glioma Stem Cell Niche.
    International journal of molecular sciences, 2021, Mar-30, Volume: 22, Issue:7

    Topics: Antineoplastic Combined Chemotherapy Protocols; Brain; Brain Neoplasms; Carcinogenesis; Cell Line, T

2021
Effects of the Anti-Tumorigenic Agent AT101 on Human Glioblastoma Cells in the Microenvironmental Glioma Stem Cell Niche.
    International journal of molecular sciences, 2021, Mar-30, Volume: 22, Issue:7

    Topics: Antineoplastic Combined Chemotherapy Protocols; Brain; Brain Neoplasms; Carcinogenesis; Cell Line, T

2021
Successful Partnerships: Exploring the Potential of Immunogenic Signals Triggered by TMZ, CX-4945, and Combined Treatment in GL261 Glioblastoma Cells.
    International journal of molecular sciences, 2021, Mar-26, Volume: 22, Issue:7

    Topics: Adenosine Triphosphate; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Prot

2021
Successful Partnerships: Exploring the Potential of Immunogenic Signals Triggered by TMZ, CX-4945, and Combined Treatment in GL261 Glioblastoma Cells.
    International journal of molecular sciences, 2021, Mar-26, Volume: 22, Issue:7

    Topics: Adenosine Triphosphate; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Prot

2021
Successful Partnerships: Exploring the Potential of Immunogenic Signals Triggered by TMZ, CX-4945, and Combined Treatment in GL261 Glioblastoma Cells.
    International journal of molecular sciences, 2021, Mar-26, Volume: 22, Issue:7

    Topics: Adenosine Triphosphate; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Prot

2021
Temozolomide-induced hypermutation is associated with distant recurrence and reduced survival after high-grade transformation of low-grade IDH-mutant gliomas.
    Neuro-oncology, 2021, 11-02, Volume: 23, Issue:11

    Topics: Brain; Brain Neoplasms; Glioma; Humans; Mutation; Neoplasm Recurrence, Local; Temozolomide

2021
Temozolomide-induced hypermutation is associated with distant recurrence and reduced survival after high-grade transformation of low-grade IDH-mutant gliomas.
    Neuro-oncology, 2021, 11-02, Volume: 23, Issue:11

    Topics: Brain; Brain Neoplasms; Glioma; Humans; Mutation; Neoplasm Recurrence, Local; Temozolomide

2021
Temozolomide-induced hypermutation is associated with distant recurrence and reduced survival after high-grade transformation of low-grade IDH-mutant gliomas.
    Neuro-oncology, 2021, 11-02, Volume: 23, Issue:11

    Topics: Brain; Brain Neoplasms; Glioma; Humans; Mutation; Neoplasm Recurrence, Local; Temozolomide

2021
Machine learning revealed stemness features and a novel stemness-based classification with appealing implications in discriminating the prognosis, immunotherapy and temozolomide responses of 906 glioblastoma patients.
    Briefings in bioinformatics, 2021, 09-02, Volume: 22, Issue:5

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Atlases as Topic; Brain Neoplasms; Female; Gene Expr

2021
Machine learning revealed stemness features and a novel stemness-based classification with appealing implications in discriminating the prognosis, immunotherapy and temozolomide responses of 906 glioblastoma patients.
    Briefings in bioinformatics, 2021, 09-02, Volume: 22, Issue:5

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Atlases as Topic; Brain Neoplasms; Female; Gene Expr

2021
Machine learning revealed stemness features and a novel stemness-based classification with appealing implications in discriminating the prognosis, immunotherapy and temozolomide responses of 906 glioblastoma patients.
    Briefings in bioinformatics, 2021, 09-02, Volume: 22, Issue:5

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Atlases as Topic; Brain Neoplasms; Female; Gene Expr

2021
PI3Kγ inhibition suppresses microglia/TAM accumulation in glioblastoma microenvironment to promote exceptional temozolomide response.
    Proceedings of the National Academy of Sciences of the United States of America, 2021, 04-20, Volume: 118, Issue:16

    Topics: Adult; Animals; Brain Neoplasms; Cell Line, Tumor; Class Ib Phosphatidylinositol 3-Kinase; Drug Resi

2021
PI3Kγ inhibition suppresses microglia/TAM accumulation in glioblastoma microenvironment to promote exceptional temozolomide response.
    Proceedings of the National Academy of Sciences of the United States of America, 2021, 04-20, Volume: 118, Issue:16

    Topics: Adult; Animals; Brain Neoplasms; Cell Line, Tumor; Class Ib Phosphatidylinositol 3-Kinase; Drug Resi

2021
PI3Kγ inhibition suppresses microglia/TAM accumulation in glioblastoma microenvironment to promote exceptional temozolomide response.
    Proceedings of the National Academy of Sciences of the United States of America, 2021, 04-20, Volume: 118, Issue:16

    Topics: Adult; Animals; Brain Neoplasms; Cell Line, Tumor; Class Ib Phosphatidylinositol 3-Kinase; Drug Resi

2021
De novo purine biosynthesis is a major driver of chemoresistance in glioblastoma.
    Brain : a journal of neurology, 2021, 05-07, Volume: 144, Issue:4

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Drug Resistance, Neoplasm; Enzyme Inhib

2021
De novo purine biosynthesis is a major driver of chemoresistance in glioblastoma.
    Brain : a journal of neurology, 2021, 05-07, Volume: 144, Issue:4

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Drug Resistance, Neoplasm; Enzyme Inhib

2021
De novo purine biosynthesis is a major driver of chemoresistance in glioblastoma.
    Brain : a journal of neurology, 2021, 05-07, Volume: 144, Issue:4

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Drug Resistance, Neoplasm; Enzyme Inhib

2021
Kinomic profile in patient-derived glioma cells during hypoxia reveals c-MET-PI3K dependency for adaptation.
    Theranostics, 2021, Volume: 11, Issue:11

    Topics: Animals; Antioxidants; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Glioblastoma; Glioma; Humans; H

2021
Kinomic profile in patient-derived glioma cells during hypoxia reveals c-MET-PI3K dependency for adaptation.
    Theranostics, 2021, Volume: 11, Issue:11

    Topics: Animals; Antioxidants; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Glioblastoma; Glioma; Humans; H

2021
Kinomic profile in patient-derived glioma cells during hypoxia reveals c-MET-PI3K dependency for adaptation.
    Theranostics, 2021, Volume: 11, Issue:11

    Topics: Animals; Antioxidants; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Glioblastoma; Glioma; Humans; H

2021
Computational modelling of perivascular-niche dynamics for the optimization of treatment schedules for glioblastoma.
    Nature biomedical engineering, 2021, Volume: 5, Issue:4

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Disease Models, Animal; Drug Administra

2021
Computational modelling of perivascular-niche dynamics for the optimization of treatment schedules for glioblastoma.
    Nature biomedical engineering, 2021, Volume: 5, Issue:4

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Disease Models, Animal; Drug Administra

2021
Computational modelling of perivascular-niche dynamics for the optimization of treatment schedules for glioblastoma.
    Nature biomedical engineering, 2021, Volume: 5, Issue:4

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Disease Models, Animal; Drug Administra

2021
Dual-triggered biomimetic vehicles enable treatment of glioblastoma through a cancer stem cell therapeutic strategy.
    Nanoscale, 2021, Apr-21, Volume: 13, Issue:15

    Topics: Biomimetics; Brain Neoplasms; Cell Line, Tumor; Glioblastoma; Humans; Neoplastic Stem Cells; Temozol

2021
Dual-triggered biomimetic vehicles enable treatment of glioblastoma through a cancer stem cell therapeutic strategy.
    Nanoscale, 2021, Apr-21, Volume: 13, Issue:15

    Topics: Biomimetics; Brain Neoplasms; Cell Line, Tumor; Glioblastoma; Humans; Neoplastic Stem Cells; Temozol

2021
Dual-triggered biomimetic vehicles enable treatment of glioblastoma through a cancer stem cell therapeutic strategy.
    Nanoscale, 2021, Apr-21, Volume: 13, Issue:15

    Topics: Biomimetics; Brain Neoplasms; Cell Line, Tumor; Glioblastoma; Humans; Neoplastic Stem Cells; Temozol

2021
Rab18 interacted with V-set and immunoglobulin domain-containing 4 (VSIG4) to involve in the apoptosis of glioma and the sensitivity to temozolomide.
    Bioengineered, 2021, Volume: 12, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation;

2021
Rab18 interacted with V-set and immunoglobulin domain-containing 4 (VSIG4) to involve in the apoptosis of glioma and the sensitivity to temozolomide.
    Bioengineered, 2021, Volume: 12, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation;

2021
Rab18 interacted with V-set and immunoglobulin domain-containing 4 (VSIG4) to involve in the apoptosis of glioma and the sensitivity to temozolomide.
    Bioengineered, 2021, Volume: 12, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation;

2021
Temozolomide-Induced Changes in Gut Microbial Composition in a Mouse Model of Brain Glioma.
    Drug design, development and therapy, 2021, Volume: 15

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Disease Models, Anima

2021
Temozolomide-Induced Changes in Gut Microbial Composition in a Mouse Model of Brain Glioma.
    Drug design, development and therapy, 2021, Volume: 15

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Disease Models, Anima

2021
Temozolomide-Induced Changes in Gut Microbial Composition in a Mouse Model of Brain Glioma.
    Drug design, development and therapy, 2021, Volume: 15

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Disease Models, Anima

2021
PCV chemotherapy alone for WHO grade 2 oligodendroglioma: prolonged disease control with low risk of malignant progression.
    Journal of neuro-oncology, 2021, Volume: 153, Issue:2

    Topics: Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Humans; Lomustine; Neoplasm Staging

2021
PCV chemotherapy alone for WHO grade 2 oligodendroglioma: prolonged disease control with low risk of malignant progression.
    Journal of neuro-oncology, 2021, Volume: 153, Issue:2

    Topics: Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Humans; Lomustine; Neoplasm Staging

2021
PCV chemotherapy alone for WHO grade 2 oligodendroglioma: prolonged disease control with low risk of malignant progression.
    Journal of neuro-oncology, 2021, Volume: 153, Issue:2

    Topics: Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Humans; Lomustine; Neoplasm Staging

2021
COXIBs and 2,5-dimethylcelecoxib counteract the hyperactivated Wnt/β-catenin pathway and COX-2/PGE2/EP4 signaling in glioblastoma cells.
    BMC cancer, 2021, May-03, Volume: 21, Issue:1

    Topics: Aged; Antineoplastic Agents, Alkylating; Apoptosis; beta Catenin; Brain Neoplasms; Celecoxib; Cell C

2021
COXIBs and 2,5-dimethylcelecoxib counteract the hyperactivated Wnt/β-catenin pathway and COX-2/PGE2/EP4 signaling in glioblastoma cells.
    BMC cancer, 2021, May-03, Volume: 21, Issue:1

    Topics: Aged; Antineoplastic Agents, Alkylating; Apoptosis; beta Catenin; Brain Neoplasms; Celecoxib; Cell C

2021
COXIBs and 2,5-dimethylcelecoxib counteract the hyperactivated Wnt/β-catenin pathway and COX-2/PGE2/EP4 signaling in glioblastoma cells.
    BMC cancer, 2021, May-03, Volume: 21, Issue:1

    Topics: Aged; Antineoplastic Agents, Alkylating; Apoptosis; beta Catenin; Brain Neoplasms; Celecoxib; Cell C

2021
Diagnosis of Pseudoprogression Following Lomustine-Temozolomide Chemoradiation in Newly Diagnosed Glioblastoma Patients Using FET-PET.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2021, 07-01, Volume: 27, Issue:13

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Brai

2021
Diagnosis of Pseudoprogression Following Lomustine-Temozolomide Chemoradiation in Newly Diagnosed Glioblastoma Patients Using FET-PET.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2021, 07-01, Volume: 27, Issue:13

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Brai

2021
Diagnosis of Pseudoprogression Following Lomustine-Temozolomide Chemoradiation in Newly Diagnosed Glioblastoma Patients Using FET-PET.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2021, 07-01, Volume: 27, Issue:13

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Brai

2021
Rabeprazole has efficacy per se and reduces resistance to temozolomide in glioma via EMT inhibition.
    Cellular oncology (Dordrecht), 2021, Volume: 44, Issue:4

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cadherins; Cell Line, Tumor; Disease Mo

2021
Rabeprazole has efficacy per se and reduces resistance to temozolomide in glioma via EMT inhibition.
    Cellular oncology (Dordrecht), 2021, Volume: 44, Issue:4

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cadherins; Cell Line, Tumor; Disease Mo

2021
Rabeprazole has efficacy per se and reduces resistance to temozolomide in glioma via EMT inhibition.
    Cellular oncology (Dordrecht), 2021, Volume: 44, Issue:4

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cadherins; Cell Line, Tumor; Disease Mo

2021
Role of circulating tumor cell detection in differentiating tumor recurrence from treatment necrosis of brain gliomas.
    Bioscience trends, 2021, May-11, Volume: 15, Issue:2

    Topics: Adult; Brain; Brain Neoplasms; Chemoradiotherapy, Adjuvant; Diagnosis, Differential; Female; Glioma;

2021
Role of circulating tumor cell detection in differentiating tumor recurrence from treatment necrosis of brain gliomas.
    Bioscience trends, 2021, May-11, Volume: 15, Issue:2

    Topics: Adult; Brain; Brain Neoplasms; Chemoradiotherapy, Adjuvant; Diagnosis, Differential; Female; Glioma;

2021
Role of circulating tumor cell detection in differentiating tumor recurrence from treatment necrosis of brain gliomas.
    Bioscience trends, 2021, May-11, Volume: 15, Issue:2

    Topics: Adult; Brain; Brain Neoplasms; Chemoradiotherapy, Adjuvant; Diagnosis, Differential; Female; Glioma;

2021
Warburg effect-promoted exosomal circ_0072083 releasing up-regulates NANGO expression through multiple pathways and enhances temozolomide resistance in glioma.
    Journal of experimental & clinical cancer research : CR, 2021, May-11, Volume: 40, Issue:1

    Topics: AlkB Homolog 5, RNA Demethylase; Antineoplastic Agents, Alkylating; Brain Neoplasms; Drug Resistance

2021
Warburg effect-promoted exosomal circ_0072083 releasing up-regulates NANGO expression through multiple pathways and enhances temozolomide resistance in glioma.
    Journal of experimental & clinical cancer research : CR, 2021, May-11, Volume: 40, Issue:1

    Topics: AlkB Homolog 5, RNA Demethylase; Antineoplastic Agents, Alkylating; Brain Neoplasms; Drug Resistance

2021
Warburg effect-promoted exosomal circ_0072083 releasing up-regulates NANGO expression through multiple pathways and enhances temozolomide resistance in glioma.
    Journal of experimental & clinical cancer research : CR, 2021, May-11, Volume: 40, Issue:1

    Topics: AlkB Homolog 5, RNA Demethylase; Antineoplastic Agents, Alkylating; Brain Neoplasms; Drug Resistance

2021
CD109-GP130 interaction drives glioblastoma stem cell plasticity and chemoresistance through STAT3 activity.
    JCI insight, 2021, 05-10, Volume: 6, Issue:9

    Topics: Animals; Antigens, CD; Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neoplasms; Cell Plastic

2021
CD109-GP130 interaction drives glioblastoma stem cell plasticity and chemoresistance through STAT3 activity.
    JCI insight, 2021, 05-10, Volume: 6, Issue:9

    Topics: Animals; Antigens, CD; Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neoplasms; Cell Plastic

2021
CD109-GP130 interaction drives glioblastoma stem cell plasticity and chemoresistance through STAT3 activity.
    JCI insight, 2021, 05-10, Volume: 6, Issue:9

    Topics: Animals; Antigens, CD; Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neoplasms; Cell Plastic

2021
EZH2 regulates the malignancy of human glioblastoma cells via modulation of Twist mRNA stability.
    European journal of pharmacology, 2021, Aug-05, Volume: 904

    Topics: Brain Neoplasms; Cell Line, Tumor; Enhancer of Zeste Homolog 2 Protein; Gene Knockdown Techniques; G

2021
EZH2 regulates the malignancy of human glioblastoma cells via modulation of Twist mRNA stability.
    European journal of pharmacology, 2021, Aug-05, Volume: 904

    Topics: Brain Neoplasms; Cell Line, Tumor; Enhancer of Zeste Homolog 2 Protein; Gene Knockdown Techniques; G

2021
EZH2 regulates the malignancy of human glioblastoma cells via modulation of Twist mRNA stability.
    European journal of pharmacology, 2021, Aug-05, Volume: 904

    Topics: Brain Neoplasms; Cell Line, Tumor; Enhancer of Zeste Homolog 2 Protein; Gene Knockdown Techniques; G

2021
Vascular priming with RRx-001 to increase the uptake and accumulation of temozolomide and irinotecan in orthotopically implanted gliomas.
    Journal of drug targeting, 2021, Volume: 29, Issue:9

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Azetidines; Brain Neoplasms; Cell Line, Tum

2021
Vascular priming with RRx-001 to increase the uptake and accumulation of temozolomide and irinotecan in orthotopically implanted gliomas.
    Journal of drug targeting, 2021, Volume: 29, Issue:9

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Azetidines; Brain Neoplasms; Cell Line, Tum

2021
Vascular priming with RRx-001 to increase the uptake and accumulation of temozolomide and irinotecan in orthotopically implanted gliomas.
    Journal of drug targeting, 2021, Volume: 29, Issue:9

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Azetidines; Brain Neoplasms; Cell Line, Tum

2021
Anaplastic glioma: benefit of temozolomide clarified.
    Nature reviews. Clinical oncology, 2021, Volume: 18, Issue:7

    Topics: Brain Neoplasms; Glioma; Humans; Temozolomide

2021
Anaplastic glioma: benefit of temozolomide clarified.
    Nature reviews. Clinical oncology, 2021, Volume: 18, Issue:7

    Topics: Brain Neoplasms; Glioma; Humans; Temozolomide

2021
Anaplastic glioma: benefit of temozolomide clarified.
    Nature reviews. Clinical oncology, 2021, Volume: 18, Issue:7

    Topics: Brain Neoplasms; Glioma; Humans; Temozolomide

2021
Heparanase confers temozolomide resistance by regulation of exosome secretion and circular RNA composition in glioma.
    Cancer science, 2021, Volume: 112, Issue:9

    Topics: Animals; Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cell Proli

2021
Heparanase confers temozolomide resistance by regulation of exosome secretion and circular RNA composition in glioma.
    Cancer science, 2021, Volume: 112, Issue:9

    Topics: Animals; Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cell Proli

2021
Heparanase confers temozolomide resistance by regulation of exosome secretion and circular RNA composition in glioma.
    Cancer science, 2021, Volume: 112, Issue:9

    Topics: Animals; Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cell Proli

2021
miR-29a sensitizes the response of glioma cells to temozolomide by modulating the P53/MDM2 feedback loop.
    Cellular & molecular biology letters, 2021, May-27, Volume: 26, Issue:1

    Topics: 3' Untranslated Regions; Antagomirs; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cell Movement; Ce

2021
miR-29a sensitizes the response of glioma cells to temozolomide by modulating the P53/MDM2 feedback loop.
    Cellular & molecular biology letters, 2021, May-27, Volume: 26, Issue:1

    Topics: 3' Untranslated Regions; Antagomirs; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cell Movement; Ce

2021
miR-29a sensitizes the response of glioma cells to temozolomide by modulating the P53/MDM2 feedback loop.
    Cellular & molecular biology letters, 2021, May-27, Volume: 26, Issue:1

    Topics: 3' Untranslated Regions; Antagomirs; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cell Movement; Ce

2021
Nanoparticle-mediated convection-enhanced delivery of a DNA intercalator to gliomas circumvents temozolomide resistance.
    Nature biomedical engineering, 2021, Volume: 5, Issue:9

    Topics: Animals; Brain Neoplasms; Cell Line, Tumor; Convection; DNA; Glioma; Humans; Intercalating Agents; M

2021
Nanoparticle-mediated convection-enhanced delivery of a DNA intercalator to gliomas circumvents temozolomide resistance.
    Nature biomedical engineering, 2021, Volume: 5, Issue:9

    Topics: Animals; Brain Neoplasms; Cell Line, Tumor; Convection; DNA; Glioma; Humans; Intercalating Agents; M

2021
Nanoparticle-mediated convection-enhanced delivery of a DNA intercalator to gliomas circumvents temozolomide resistance.
    Nature biomedical engineering, 2021, Volume: 5, Issue:9

    Topics: Animals; Brain Neoplasms; Cell Line, Tumor; Convection; DNA; Glioma; Humans; Intercalating Agents; M

2021
Elevated GIGYF2 expression suppresses tumor migration and enhances sensitivity to temozolomide in malignant glioma.
    Cancer gene therapy, 2022, Volume: 29, Issue:6

    Topics: Brain Neoplasms; Carrier Proteins; Cell Line, Tumor; Cell Movement; Cell Proliferation; Glioma; Huma

2022
Elevated GIGYF2 expression suppresses tumor migration and enhances sensitivity to temozolomide in malignant glioma.
    Cancer gene therapy, 2022, Volume: 29, Issue:6

    Topics: Brain Neoplasms; Carrier Proteins; Cell Line, Tumor; Cell Movement; Cell Proliferation; Glioma; Huma

2022
Elevated GIGYF2 expression suppresses tumor migration and enhances sensitivity to temozolomide in malignant glioma.
    Cancer gene therapy, 2022, Volume: 29, Issue:6

    Topics: Brain Neoplasms; Carrier Proteins; Cell Line, Tumor; Cell Movement; Cell Proliferation; Glioma; Huma

2022
Caffeine Inhibits Growth of Temozolomide-Treated Glioma via Increasing Autophagy and Apoptosis but Not via Modulating Hypoxia, Angiogenesis, or Endoplasmic Reticulum Stress in Rats.
    Nutrition and cancer, 2022, Volume: 74, Issue:3

    Topics: Animals; Apoptosis; Autophagy; Brain Neoplasms; Caffeine; Cell Line, Tumor; Endoplasmic Reticulum St

2022
Caffeine Inhibits Growth of Temozolomide-Treated Glioma via Increasing Autophagy and Apoptosis but Not via Modulating Hypoxia, Angiogenesis, or Endoplasmic Reticulum Stress in Rats.
    Nutrition and cancer, 2022, Volume: 74, Issue:3

    Topics: Animals; Apoptosis; Autophagy; Brain Neoplasms; Caffeine; Cell Line, Tumor; Endoplasmic Reticulum St

2022
Caffeine Inhibits Growth of Temozolomide-Treated Glioma via Increasing Autophagy and Apoptosis but Not via Modulating Hypoxia, Angiogenesis, or Endoplasmic Reticulum Stress in Rats.
    Nutrition and cancer, 2022, Volume: 74, Issue:3

    Topics: Animals; Apoptosis; Autophagy; Brain Neoplasms; Caffeine; Cell Line, Tumor; Endoplasmic Reticulum St

2022
Transcriptional CDK Inhibitors CYC065 and THZ1 Induce Apoptosis in Glioma Stem Cells Derived from Recurrent GBM.
    Cells, 2021, 05-12, Volume: 10, Issue:5

    Topics: AC133 Antigen; Adenosine; Adult; Antineoplastic Agents; Apoptosis; Brain Neoplasms; Cell Cycle Check

2021
Transcriptional CDK Inhibitors CYC065 and THZ1 Induce Apoptosis in Glioma Stem Cells Derived from Recurrent GBM.
    Cells, 2021, 05-12, Volume: 10, Issue:5

    Topics: AC133 Antigen; Adenosine; Adult; Antineoplastic Agents; Apoptosis; Brain Neoplasms; Cell Cycle Check

2021
Transcriptional CDK Inhibitors CYC065 and THZ1 Induce Apoptosis in Glioma Stem Cells Derived from Recurrent GBM.
    Cells, 2021, 05-12, Volume: 10, Issue:5

    Topics: AC133 Antigen; Adenosine; Adult; Antineoplastic Agents; Apoptosis; Brain Neoplasms; Cell Cycle Check

2021
Enhanced Anti-Tumor Activity in Mice with Temozolomide-Resistant Human Glioblastoma Cell Line-Derived Xenograft Using SN-38-Incorporated Polymeric Microparticle.
    International journal of molecular sciences, 2021, May-24, Volume: 22, Issue:11

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Brain Neoplasms; Cell Line, Tumo

2021
Enhanced Anti-Tumor Activity in Mice with Temozolomide-Resistant Human Glioblastoma Cell Line-Derived Xenograft Using SN-38-Incorporated Polymeric Microparticle.
    International journal of molecular sciences, 2021, May-24, Volume: 22, Issue:11

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Brain Neoplasms; Cell Line, Tumo

2021
Enhanced Anti-Tumor Activity in Mice with Temozolomide-Resistant Human Glioblastoma Cell Line-Derived Xenograft Using SN-38-Incorporated Polymeric Microparticle.
    International journal of molecular sciences, 2021, May-24, Volume: 22, Issue:11

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Brain Neoplasms; Cell Line, Tumo

2021
Receptor-Interacting Protein 140 Enhanced Temozolomide-Induced Cellular Apoptosis Through Regulation of E2F1 in Human Glioma Cell Lines.
    Neuromolecular medicine, 2022, Volume: 24, Issue:2

    Topics: Apoptosis; Brain Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; E2F1 Transcription Factor;

2022
Receptor-Interacting Protein 140 Enhanced Temozolomide-Induced Cellular Apoptosis Through Regulation of E2F1 in Human Glioma Cell Lines.
    Neuromolecular medicine, 2022, Volume: 24, Issue:2

    Topics: Apoptosis; Brain Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; E2F1 Transcription Factor;

2022
Receptor-Interacting Protein 140 Enhanced Temozolomide-Induced Cellular Apoptosis Through Regulation of E2F1 in Human Glioma Cell Lines.
    Neuromolecular medicine, 2022, Volume: 24, Issue:2

    Topics: Apoptosis; Brain Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; E2F1 Transcription Factor;

2022
[Glioblastoma].
    No shinkei geka. Neurological surgery, 2021, Volume: 49, Issue:3

    Topics: Brain Neoplasms; Glioblastoma; Humans; Japan; Neoplasm Recurrence, Local; Temozolomide

2021
[Glioblastoma].
    No shinkei geka. Neurological surgery, 2021, Volume: 49, Issue:3

    Topics: Brain Neoplasms; Glioblastoma; Humans; Japan; Neoplasm Recurrence, Local; Temozolomide

2021
[Glioblastoma].
    No shinkei geka. Neurological surgery, 2021, Volume: 49, Issue:3

    Topics: Brain Neoplasms; Glioblastoma; Humans; Japan; Neoplasm Recurrence, Local; Temozolomide

2021
A Nanoantidote Alleviates Glioblastoma Chemotoxicity without Efficacy Compromise.
    Nano letters, 2021, 06-23, Volume: 21, Issue:12

    Topics: Animals; Antineoplastic Agents, Alkylating; Blood-Brain Barrier; Brain Neoplasms; Cell Line, Tumor;

2021
A Nanoantidote Alleviates Glioblastoma Chemotoxicity without Efficacy Compromise.
    Nano letters, 2021, 06-23, Volume: 21, Issue:12

    Topics: Animals; Antineoplastic Agents, Alkylating; Blood-Brain Barrier; Brain Neoplasms; Cell Line, Tumor;

2021
A Nanoantidote Alleviates Glioblastoma Chemotoxicity without Efficacy Compromise.
    Nano letters, 2021, 06-23, Volume: 21, Issue:12

    Topics: Animals; Antineoplastic Agents, Alkylating; Blood-Brain Barrier; Brain Neoplasms; Cell Line, Tumor;

2021
Development of CD133 Targeting Multi-Drug Polymer Micellar Nanoparticles for Glioblastoma - In Vitro Evaluation in Glioblastoma Stem Cells.
    Pharmaceutical research, 2021, Volume: 38, Issue:6

    Topics: AC133 Antigen; Animals; Brain Neoplasms; Cell Line, Tumor; Dose-Response Relationship, Drug; Drug De

2021
Development of CD133 Targeting Multi-Drug Polymer Micellar Nanoparticles for Glioblastoma - In Vitro Evaluation in Glioblastoma Stem Cells.
    Pharmaceutical research, 2021, Volume: 38, Issue:6

    Topics: AC133 Antigen; Animals; Brain Neoplasms; Cell Line, Tumor; Dose-Response Relationship, Drug; Drug De

2021
Development of CD133 Targeting Multi-Drug Polymer Micellar Nanoparticles for Glioblastoma - In Vitro Evaluation in Glioblastoma Stem Cells.
    Pharmaceutical research, 2021, Volume: 38, Issue:6

    Topics: AC133 Antigen; Animals; Brain Neoplasms; Cell Line, Tumor; Dose-Response Relationship, Drug; Drug De

2021
Localization matters: nuclear-trapped Survivin sensitizes glioblastoma cells to temozolomide by elevating cellular senescence and impairing homologous recombination.
    Cellular and molecular life sciences : CMLS, 2021, Volume: 78, Issue:14

    Topics: Animals; Antineoplastic Agents, Alkylating; Apoptosis; Biomarkers, Tumor; Brain Neoplasms; Cell Nucl

2021
Localization matters: nuclear-trapped Survivin sensitizes glioblastoma cells to temozolomide by elevating cellular senescence and impairing homologous recombination.
    Cellular and molecular life sciences : CMLS, 2021, Volume: 78, Issue:14

    Topics: Animals; Antineoplastic Agents, Alkylating; Apoptosis; Biomarkers, Tumor; Brain Neoplasms; Cell Nucl

2021
Localization matters: nuclear-trapped Survivin sensitizes glioblastoma cells to temozolomide by elevating cellular senescence and impairing homologous recombination.
    Cellular and molecular life sciences : CMLS, 2021, Volume: 78, Issue:14

    Topics: Animals; Antineoplastic Agents, Alkylating; Apoptosis; Biomarkers, Tumor; Brain Neoplasms; Cell Nucl

2021
Combination chemotherapy versus temozolomide for patients with methylated MGMT (m-MGMT) glioblastoma: results of computational biological modeling to predict the magnitude of treatment benefit.
    Journal of neuro-oncology, 2021, Volume: 153, Issue:3

    Topics: Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Artificial Intell

2021
Combination chemotherapy versus temozolomide for patients with methylated MGMT (m-MGMT) glioblastoma: results of computational biological modeling to predict the magnitude of treatment benefit.
    Journal of neuro-oncology, 2021, Volume: 153, Issue:3

    Topics: Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Artificial Intell

2021
Combination chemotherapy versus temozolomide for patients with methylated MGMT (m-MGMT) glioblastoma: results of computational biological modeling to predict the magnitude of treatment benefit.
    Journal of neuro-oncology, 2021, Volume: 153, Issue:3

    Topics: Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Artificial Intell

2021
Experimental design of preclinical experiments: number of PDX lines vs subsampling within PDX lines.
    Neuro-oncology, 2021, 12-01, Volume: 23, Issue:12

    Topics: Animals; Brain Neoplasms; Cell Line, Tumor; Glioblastoma; Mice; Research Design; Retrospective Studi

2021
Experimental design of preclinical experiments: number of PDX lines vs subsampling within PDX lines.
    Neuro-oncology, 2021, 12-01, Volume: 23, Issue:12

    Topics: Animals; Brain Neoplasms; Cell Line, Tumor; Glioblastoma; Mice; Research Design; Retrospective Studi

2021
Experimental design of preclinical experiments: number of PDX lines vs subsampling within PDX lines.
    Neuro-oncology, 2021, 12-01, Volume: 23, Issue:12

    Topics: Animals; Brain Neoplasms; Cell Line, Tumor; Glioblastoma; Mice; Research Design; Retrospective Studi

2021
miR-23b-5p promotes the chemosensitivity of temozolomide via negatively regulating TLR4 in glioma.
    Acta biochimica et biophysica Sinica, 2021, Jul-28, Volume: 53, Issue:8

    Topics: Brain Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; Glioma; Humans; MicroRNAs; Neoplasm Pr

2021
miR-23b-5p promotes the chemosensitivity of temozolomide via negatively regulating TLR4 in glioma.
    Acta biochimica et biophysica Sinica, 2021, Jul-28, Volume: 53, Issue:8

    Topics: Brain Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; Glioma; Humans; MicroRNAs; Neoplasm Pr

2021
miR-23b-5p promotes the chemosensitivity of temozolomide via negatively regulating TLR4 in glioma.
    Acta biochimica et biophysica Sinica, 2021, Jul-28, Volume: 53, Issue:8

    Topics: Brain Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; Glioma; Humans; MicroRNAs; Neoplasm Pr

2021
Clinical Features and Prognostic Factors of Pediatric Glioblastoma: Report of 38 Cases.
    World neurosurgery, 2021, Volume: 153

    Topics: Adolescent; Antineoplastic Agents, Alkylating; Apraxias; Brain Neoplasms; Chemoradiotherapy, Adjuvan

2021
Clinical Features and Prognostic Factors of Pediatric Glioblastoma: Report of 38 Cases.
    World neurosurgery, 2021, Volume: 153

    Topics: Adolescent; Antineoplastic Agents, Alkylating; Apraxias; Brain Neoplasms; Chemoradiotherapy, Adjuvan

2021
Clinical Features and Prognostic Factors of Pediatric Glioblastoma: Report of 38 Cases.
    World neurosurgery, 2021, Volume: 153

    Topics: Adolescent; Antineoplastic Agents, Alkylating; Apraxias; Brain Neoplasms; Chemoradiotherapy, Adjuvan

2021
Prediction of Glioma Stemlike Cell Infiltration in the Non-Contrast-Enhancing Area by Quantitative Measurement of Lactate on Magnetic Resonance Spectroscopy in Glioblastoma.
    World neurosurgery, 2021, Volume: 153

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherap

2021
Prediction of Glioma Stemlike Cell Infiltration in the Non-Contrast-Enhancing Area by Quantitative Measurement of Lactate on Magnetic Resonance Spectroscopy in Glioblastoma.
    World neurosurgery, 2021, Volume: 153

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherap

2021
Prediction of Glioma Stemlike Cell Infiltration in the Non-Contrast-Enhancing Area by Quantitative Measurement of Lactate on Magnetic Resonance Spectroscopy in Glioblastoma.
    World neurosurgery, 2021, Volume: 153

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherap

2021
Synthesis and Characterization of a Series of Temozolomide Esters and Its Anti-glioma Study.
    Journal of pharmaceutical sciences, 2021, Volume: 110, Issue:10

    Topics: Animals; Brain Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; Esters; Glioblastoma; Glioma;

2021
Synthesis and Characterization of a Series of Temozolomide Esters and Its Anti-glioma Study.
    Journal of pharmaceutical sciences, 2021, Volume: 110, Issue:10

    Topics: Animals; Brain Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; Esters; Glioblastoma; Glioma;

2021
Synthesis and Characterization of a Series of Temozolomide Esters and Its Anti-glioma Study.
    Journal of pharmaceutical sciences, 2021, Volume: 110, Issue:10

    Topics: Animals; Brain Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; Esters; Glioblastoma; Glioma;

2021
17β-estradiol induces temozolomide resistance through NRF2-mediated redox homeostasis in glioblastoma.
    Free radical biology & medicine, 2021, 08-20, Volume: 172

    Topics: Apoptosis; Brain Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; Estradiol; Glioblastoma; Ho

2021
17β-estradiol induces temozolomide resistance through NRF2-mediated redox homeostasis in glioblastoma.
    Free radical biology & medicine, 2021, 08-20, Volume: 172

    Topics: Apoptosis; Brain Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; Estradiol; Glioblastoma; Ho

2021
17β-estradiol induces temozolomide resistance through NRF2-mediated redox homeostasis in glioblastoma.
    Free radical biology & medicine, 2021, 08-20, Volume: 172

    Topics: Apoptosis; Brain Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; Estradiol; Glioblastoma; Ho

2021
Captopril inhibits Matrix Metalloproteinase-2 and extends survival as a temozolomide adjuvant in an intracranial gliosarcoma model.
    Clinical neurology and neurosurgery, 2021, Volume: 207

    Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Antineoplastic Agents, Alkylating; Brain Neoplasm

2021
Captopril inhibits Matrix Metalloproteinase-2 and extends survival as a temozolomide adjuvant in an intracranial gliosarcoma model.
    Clinical neurology and neurosurgery, 2021, Volume: 207

    Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Antineoplastic Agents, Alkylating; Brain Neoplasm

2021
Captopril inhibits Matrix Metalloproteinase-2 and extends survival as a temozolomide adjuvant in an intracranial gliosarcoma model.
    Clinical neurology and neurosurgery, 2021, Volume: 207

    Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Antineoplastic Agents, Alkylating; Brain Neoplasm

2021
Preclinical modeling in glioblastoma patient-derived xenograft (GBM PDX) xenografts to guide clinical development of lisavanbulin-a novel tumor checkpoint controller targeting microtubules.
    Neuro-oncology, 2022, 03-12, Volume: 24, Issue:3

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Glioblastoma; Heterografts; Humans; Mic

2022
Preclinical modeling in glioblastoma patient-derived xenograft (GBM PDX) xenografts to guide clinical development of lisavanbulin-a novel tumor checkpoint controller targeting microtubules.
    Neuro-oncology, 2022, 03-12, Volume: 24, Issue:3

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Glioblastoma; Heterografts; Humans; Mic

2022
Preclinical modeling in glioblastoma patient-derived xenograft (GBM PDX) xenografts to guide clinical development of lisavanbulin-a novel tumor checkpoint controller targeting microtubules.
    Neuro-oncology, 2022, 03-12, Volume: 24, Issue:3

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Glioblastoma; Heterografts; Humans; Mic

2022
Do elderly patients (≥ 75 years old) with glioblastoma benefit from more radical surgeries in the era of temozolomide?
    Neurosurgical review, 2022, Volume: 45, Issue:1

    Topics: Aged; Brain Neoplasms; Glioblastoma; Humans; Neurosurgical Procedures; Prognosis; Retrospective Stud

2022
Do elderly patients (≥ 75 years old) with glioblastoma benefit from more radical surgeries in the era of temozolomide?
    Neurosurgical review, 2022, Volume: 45, Issue:1

    Topics: Aged; Brain Neoplasms; Glioblastoma; Humans; Neurosurgical Procedures; Prognosis; Retrospective Stud

2022
Do elderly patients (≥ 75 years old) with glioblastoma benefit from more radical surgeries in the era of temozolomide?
    Neurosurgical review, 2022, Volume: 45, Issue:1

    Topics: Aged; Brain Neoplasms; Glioblastoma; Humans; Neurosurgical Procedures; Prognosis; Retrospective Stud

2022
Upfront Therapy of Aggressive/High-Risk Low-Grade Glioma: Single-Institution Outcome Analysis of Temozolomide-Based Radio-Chemotherapy and Adjuvant Chemotherapy.
    World neurosurgery, 2021, Volume: 154

    Topics: Adult; Antineoplastic Agents, Alkylating; Astrocytoma; Biomarkers, Tumor; Brain Neoplasms; Chemoradi

2021
Upfront Therapy of Aggressive/High-Risk Low-Grade Glioma: Single-Institution Outcome Analysis of Temozolomide-Based Radio-Chemotherapy and Adjuvant Chemotherapy.
    World neurosurgery, 2021, Volume: 154

    Topics: Adult; Antineoplastic Agents, Alkylating; Astrocytoma; Biomarkers, Tumor; Brain Neoplasms; Chemoradi

2021
Upfront Therapy of Aggressive/High-Risk Low-Grade Glioma: Single-Institution Outcome Analysis of Temozolomide-Based Radio-Chemotherapy and Adjuvant Chemotherapy.
    World neurosurgery, 2021, Volume: 154

    Topics: Adult; Antineoplastic Agents, Alkylating; Astrocytoma; Biomarkers, Tumor; Brain Neoplasms; Chemoradi

2021
The function and mechanism of the JARID2/CCND1 axis in modulating glioma cell growth and sensitivity to temozolomide (TMZ).
    Cancer biology & therapy, 2021, 06-03, Volume: 22, Issue:5-6

    Topics: Brain Neoplasms; Cell Line, Tumor; Cyclin D1; Drug Resistance, Neoplasm; Glioma; Humans; MicroRNAs;

2021
The function and mechanism of the JARID2/CCND1 axis in modulating glioma cell growth and sensitivity to temozolomide (TMZ).
    Cancer biology & therapy, 2021, 06-03, Volume: 22, Issue:5-6

    Topics: Brain Neoplasms; Cell Line, Tumor; Cyclin D1; Drug Resistance, Neoplasm; Glioma; Humans; MicroRNAs;

2021
The function and mechanism of the JARID2/CCND1 axis in modulating glioma cell growth and sensitivity to temozolomide (TMZ).
    Cancer biology & therapy, 2021, 06-03, Volume: 22, Issue:5-6

    Topics: Brain Neoplasms; Cell Line, Tumor; Cyclin D1; Drug Resistance, Neoplasm; Glioma; Humans; MicroRNAs;

2021
CD90
    Stem cell research & therapy, 2021, 07-13, Volume: 12, Issue:1

    Topics: Animals; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Drug Resistance, Neoplasm

2021
CD90
    Stem cell research & therapy, 2021, 07-13, Volume: 12, Issue:1

    Topics: Animals; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Drug Resistance, Neoplasm

2021
CD90
    Stem cell research & therapy, 2021, 07-13, Volume: 12, Issue:1

    Topics: Animals; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Drug Resistance, Neoplasm

2021
Oncological and functional outcomes of supratotal resection of IDH1 wild-type glioblastoma based on
    Scientific reports, 2021, 07-15, Volume: 11, Issue:1

    Topics: Adult; Aged; Brain Neoplasms; Carbon Radioisotopes; Contrast Media; Craniotomy; Female; Glioblastoma

2021
Oncological and functional outcomes of supratotal resection of IDH1 wild-type glioblastoma based on
    Scientific reports, 2021, 07-15, Volume: 11, Issue:1

    Topics: Adult; Aged; Brain Neoplasms; Carbon Radioisotopes; Contrast Media; Craniotomy; Female; Glioblastoma

2021
Oncological and functional outcomes of supratotal resection of IDH1 wild-type glioblastoma based on
    Scientific reports, 2021, 07-15, Volume: 11, Issue:1

    Topics: Adult; Aged; Brain Neoplasms; Carbon Radioisotopes; Contrast Media; Craniotomy; Female; Glioblastoma

2021
A Noninvasive Gut-to-Brain Oral Drug Delivery System for Treating Brain Tumors.
    Advanced materials (Deerfield Beach, Fla.), 2021, Volume: 33, Issue:34

    Topics: Administration, Oral; Animals; Antineoplastic Agents; beta-Glucans; Blood-Brain Barrier; Brain Neopl

2021
A Noninvasive Gut-to-Brain Oral Drug Delivery System for Treating Brain Tumors.
    Advanced materials (Deerfield Beach, Fla.), 2021, Volume: 33, Issue:34

    Topics: Administration, Oral; Animals; Antineoplastic Agents; beta-Glucans; Blood-Brain Barrier; Brain Neopl

2021
A Noninvasive Gut-to-Brain Oral Drug Delivery System for Treating Brain Tumors.
    Advanced materials (Deerfield Beach, Fla.), 2021, Volume: 33, Issue:34

    Topics: Administration, Oral; Animals; Antineoplastic Agents; beta-Glucans; Blood-Brain Barrier; Brain Neopl

2021
Clinical study of apatinib plus temozolomide for the treatment of recurrent high-grade gliomas.
    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2021, Volume: 90

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Brain Neoplasms;

2021
Clinical study of apatinib plus temozolomide for the treatment of recurrent high-grade gliomas.
    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2021, Volume: 90

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Brain Neoplasms;

2021
Clinical study of apatinib plus temozolomide for the treatment of recurrent high-grade gliomas.
    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2021, Volume: 90

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Brain Neoplasms;

2021
Exosomal transfer of miR‑25‑3p promotes the proliferation and temozolomide resistance of glioblastoma cells by targeting FBXW7.
    International journal of oncology, 2021, Volume: 59, Issue:2

    Topics: Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Cell Survival; Drug Resistance, Neoplasm; Exo

2021
Exosomal transfer of miR‑25‑3p promotes the proliferation and temozolomide resistance of glioblastoma cells by targeting FBXW7.
    International journal of oncology, 2021, Volume: 59, Issue:2

    Topics: Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Cell Survival; Drug Resistance, Neoplasm; Exo

2021
Exosomal transfer of miR‑25‑3p promotes the proliferation and temozolomide resistance of glioblastoma cells by targeting FBXW7.
    International journal of oncology, 2021, Volume: 59, Issue:2

    Topics: Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Cell Survival; Drug Resistance, Neoplasm; Exo

2021
Synergistic Effect of Gefitinib and Temozolomide on U87MG Glioblastoma Angiogenesis.
    Nutrition and cancer, 2022, Volume: 74, Issue:4

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; Dru

2022
Synergistic Effect of Gefitinib and Temozolomide on U87MG Glioblastoma Angiogenesis.
    Nutrition and cancer, 2022, Volume: 74, Issue:4

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; Dru

2022
Synergistic Effect of Gefitinib and Temozolomide on U87MG Glioblastoma Angiogenesis.
    Nutrition and cancer, 2022, Volume: 74, Issue:4

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; Dru

2022
Long-term survival of an adolescent glioblastoma patient under treatment with vinblastine and valproic acid illustrates importance of methylation profiling.
    Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 2022, Volume: 38, Issue:2

    Topics: Adolescent; Brain Neoplasms; Glioblastoma; Humans; Methylation; Prognosis; Temozolomide; Valproic Ac

2022
Long-term survival of an adolescent glioblastoma patient under treatment with vinblastine and valproic acid illustrates importance of methylation profiling.
    Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 2022, Volume: 38, Issue:2

    Topics: Adolescent; Brain Neoplasms; Glioblastoma; Humans; Methylation; Prognosis; Temozolomide; Valproic Ac

2022
Long-term survival of an adolescent glioblastoma patient under treatment with vinblastine and valproic acid illustrates importance of methylation profiling.
    Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 2022, Volume: 38, Issue:2

    Topics: Adolescent; Brain Neoplasms; Glioblastoma; Humans; Methylation; Prognosis; Temozolomide; Valproic Ac

2022
Is the Duration of Temozolomide Predictive for Sequential Bevacizumab Treatment Responses in the Glioblastoma Multiforme Cancer Setting?
    Journal of the College of Physicians and Surgeons--Pakistan : JCPSP, 2021, Volume: 31, Issue:8

    Topics: Antineoplastic Agents, Alkylating; Bevacizumab; Brain Neoplasms; Female; Glioblastoma; Humans; Male;

2021
Is the Duration of Temozolomide Predictive for Sequential Bevacizumab Treatment Responses in the Glioblastoma Multiforme Cancer Setting?
    Journal of the College of Physicians and Surgeons--Pakistan : JCPSP, 2021, Volume: 31, Issue:8

    Topics: Antineoplastic Agents, Alkylating; Bevacizumab; Brain Neoplasms; Female; Glioblastoma; Humans; Male;

2021
Is the Duration of Temozolomide Predictive for Sequential Bevacizumab Treatment Responses in the Glioblastoma Multiforme Cancer Setting?
    Journal of the College of Physicians and Surgeons--Pakistan : JCPSP, 2021, Volume: 31, Issue:8

    Topics: Antineoplastic Agents, Alkylating; Bevacizumab; Brain Neoplasms; Female; Glioblastoma; Humans; Male;

2021
Volumetric study reveals the relationship between outcome and early radiographic response during bevacizumab-containing chemoradiotherapy for unresectable glioblastoma.
    Journal of neuro-oncology, 2021, Volume: 154, Issue:2

    Topics: Bevacizumab; Brain Neoplasms; Chemoradiotherapy; Gadolinium; Glioblastoma; Humans; Temozolomide; Tre

2021
Volumetric study reveals the relationship between outcome and early radiographic response during bevacizumab-containing chemoradiotherapy for unresectable glioblastoma.
    Journal of neuro-oncology, 2021, Volume: 154, Issue:2

    Topics: Bevacizumab; Brain Neoplasms; Chemoradiotherapy; Gadolinium; Glioblastoma; Humans; Temozolomide; Tre

2021
Volumetric study reveals the relationship between outcome and early radiographic response during bevacizumab-containing chemoradiotherapy for unresectable glioblastoma.
    Journal of neuro-oncology, 2021, Volume: 154, Issue:2

    Topics: Bevacizumab; Brain Neoplasms; Chemoradiotherapy; Gadolinium; Glioblastoma; Humans; Temozolomide; Tre

2021
The protein kinase LKB1 promotes self-renewal and blocks invasiveness in glioblastoma.
    Journal of cellular physiology, 2022, Volume: 237, Issue:1

    Topics: AMP-Activated Protein Kinase Kinases; Animals; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation

2022
The protein kinase LKB1 promotes self-renewal and blocks invasiveness in glioblastoma.
    Journal of cellular physiology, 2022, Volume: 237, Issue:1

    Topics: AMP-Activated Protein Kinase Kinases; Animals; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation

2022
The protein kinase LKB1 promotes self-renewal and blocks invasiveness in glioblastoma.
    Journal of cellular physiology, 2022, Volume: 237, Issue:1

    Topics: AMP-Activated Protein Kinase Kinases; Animals; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation

2022
Leukemia associated RUNX1T1 gene reduced proliferation and invasiveness of glioblastoma cells.
    Journal of cellular biochemistry, 2021, Volume: 122, Issue:11

    Topics: Adult; Aged; Aged, 80 and over; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Female; Gene

2021
Leukemia associated RUNX1T1 gene reduced proliferation and invasiveness of glioblastoma cells.
    Journal of cellular biochemistry, 2021, Volume: 122, Issue:11

    Topics: Adult; Aged; Aged, 80 and over; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Female; Gene

2021
Leukemia associated RUNX1T1 gene reduced proliferation and invasiveness of glioblastoma cells.
    Journal of cellular biochemistry, 2021, Volume: 122, Issue:11

    Topics: Adult; Aged; Aged, 80 and over; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Female; Gene

2021
Molecular Characterization of AEBP1 at Transcriptional Level in Glioma.
    BioMed research international, 2021, Volume: 2021

    Topics: Brain Neoplasms; Carboxypeptidases; Cell Line, Tumor; Databases, Genetic; DNA Methylation; DNA Modif

2021
Molecular Characterization of AEBP1 at Transcriptional Level in Glioma.
    BioMed research international, 2021, Volume: 2021

    Topics: Brain Neoplasms; Carboxypeptidases; Cell Line, Tumor; Databases, Genetic; DNA Methylation; DNA Modif

2021
Molecular Characterization of AEBP1 at Transcriptional Level in Glioma.
    BioMed research international, 2021, Volume: 2021

    Topics: Brain Neoplasms; Carboxypeptidases; Cell Line, Tumor; Databases, Genetic; DNA Methylation; DNA Modif

2021
Effects of platinum-coexisting dopamine with X-ray irradiation upon human glioblastoma cell proliferation.
    Human cell, 2021, Volume: 34, Issue:6

    Topics: Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Cells, Cultured; Combined Modality Therapy; D

2021
Effects of platinum-coexisting dopamine with X-ray irradiation upon human glioblastoma cell proliferation.
    Human cell, 2021, Volume: 34, Issue:6

    Topics: Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Cells, Cultured; Combined Modality Therapy; D

2021
Effects of platinum-coexisting dopamine with X-ray irradiation upon human glioblastoma cell proliferation.
    Human cell, 2021, Volume: 34, Issue:6

    Topics: Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Cells, Cultured; Combined Modality Therapy; D

2021
Long noncoding RNA just proximal to X-inactive specific transcript facilitates aerobic glycolysis and temozolomide chemoresistance by promoting stability of PDK1 mRNA in an m6A-dependent manner in glioblastoma multiforme cells.
    Cancer science, 2021, Volume: 112, Issue:11

    Topics: Adenosine; Aerobiosis; Alpha-Ketoglutarate-Dependent Dioxygenase FTO; Antineoplastic Agents, Alkylat

2021
Long noncoding RNA just proximal to X-inactive specific transcript facilitates aerobic glycolysis and temozolomide chemoresistance by promoting stability of PDK1 mRNA in an m6A-dependent manner in glioblastoma multiforme cells.
    Cancer science, 2021, Volume: 112, Issue:11

    Topics: Adenosine; Aerobiosis; Alpha-Ketoglutarate-Dependent Dioxygenase FTO; Antineoplastic Agents, Alkylat

2021
Long noncoding RNA just proximal to X-inactive specific transcript facilitates aerobic glycolysis and temozolomide chemoresistance by promoting stability of PDK1 mRNA in an m6A-dependent manner in glioblastoma multiforme cells.
    Cancer science, 2021, Volume: 112, Issue:11

    Topics: Adenosine; Aerobiosis; Alpha-Ketoglutarate-Dependent Dioxygenase FTO; Antineoplastic Agents, Alkylat

2021
Treating ICB-resistant glioma with anti-CD40 and mitotic spindle checkpoint controller BAL101553 (lisavanbulin).
    JCI insight, 2021, 09-22, Volume: 6, Issue:18

    Topics: Animals; Antibodies, Monoclonal; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemothe

2021
Treating ICB-resistant glioma with anti-CD40 and mitotic spindle checkpoint controller BAL101553 (lisavanbulin).
    JCI insight, 2021, 09-22, Volume: 6, Issue:18

    Topics: Animals; Antibodies, Monoclonal; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemothe

2021
Treating ICB-resistant glioma with anti-CD40 and mitotic spindle checkpoint controller BAL101553 (lisavanbulin).
    JCI insight, 2021, 09-22, Volume: 6, Issue:18

    Topics: Animals; Antibodies, Monoclonal; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemothe

2021
Tailoring drug co-delivery nanosystem for mitigating U-87 stem cells drug resistance.
    Drug delivery and translational research, 2022, Volume: 12, Issue:5

    Topics: Apoptosis; Brain Neoplasms; Cell Line, Tumor; Dendrimers; Drug Resistance; Drug Resistance, Neoplasm

2022
Tailoring drug co-delivery nanosystem for mitigating U-87 stem cells drug resistance.
    Drug delivery and translational research, 2022, Volume: 12, Issue:5

    Topics: Apoptosis; Brain Neoplasms; Cell Line, Tumor; Dendrimers; Drug Resistance; Drug Resistance, Neoplasm

2022
Tailoring drug co-delivery nanosystem for mitigating U-87 stem cells drug resistance.
    Drug delivery and translational research, 2022, Volume: 12, Issue:5

    Topics: Apoptosis; Brain Neoplasms; Cell Line, Tumor; Dendrimers; Drug Resistance; Drug Resistance, Neoplasm

2022
Molecular characteristics of single patient-derived glioma stem-like cells from primary and recurrent glioblastoma.
    Anti-cancer drugs, 2022, 01-01, Volume: 33, Issue:1

    Topics: Animals; Brain Neoplasms; Cell Proliferation; Drug Resistance, Neoplasm; Gene Expression Regulation;

2022
Molecular characteristics of single patient-derived glioma stem-like cells from primary and recurrent glioblastoma.
    Anti-cancer drugs, 2022, 01-01, Volume: 33, Issue:1

    Topics: Animals; Brain Neoplasms; Cell Proliferation; Drug Resistance, Neoplasm; Gene Expression Regulation;

2022
Molecular characteristics of single patient-derived glioma stem-like cells from primary and recurrent glioblastoma.
    Anti-cancer drugs, 2022, 01-01, Volume: 33, Issue:1

    Topics: Animals; Brain Neoplasms; Cell Proliferation; Drug Resistance, Neoplasm; Gene Expression Regulation;

2022
Epigenetic instability may alter cell state transitions and anticancer drug resistance.
    PLoS computational biology, 2021, Volume: 17, Issue:8

    Topics: Antineoplastic Agents; Antineoplastic Agents, Alkylating; Brain Neoplasms; Drug Resistance, Neoplasm

2021
Epigenetic instability may alter cell state transitions and anticancer drug resistance.
    PLoS computational biology, 2021, Volume: 17, Issue:8

    Topics: Antineoplastic Agents; Antineoplastic Agents, Alkylating; Brain Neoplasms; Drug Resistance, Neoplasm

2021
Epigenetic instability may alter cell state transitions and anticancer drug resistance.
    PLoS computational biology, 2021, Volume: 17, Issue:8

    Topics: Antineoplastic Agents; Antineoplastic Agents, Alkylating; Brain Neoplasms; Drug Resistance, Neoplasm

2021
Combinatorial Effect of Temozolomide and Naringenin in Human Glioblastoma Multiforme Cell Lines.
    Nutrition and cancer, 2022, Volume: 74, Issue:3

    Topics: Antineoplastic Agents; Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cell Line, Tum

2022
Combinatorial Effect of Temozolomide and Naringenin in Human Glioblastoma Multiforme Cell Lines.
    Nutrition and cancer, 2022, Volume: 74, Issue:3

    Topics: Antineoplastic Agents; Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cell Line, Tum

2022
Combinatorial Effect of Temozolomide and Naringenin in Human Glioblastoma Multiforme Cell Lines.
    Nutrition and cancer, 2022, Volume: 74, Issue:3

    Topics: Antineoplastic Agents; Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cell Line, Tum

2022
Silencing lncRNA LINC01410 suppresses cell viability yet promotes apoptosis and sensitivity to temozolomide in glioblastoma cells by inactivating PTEN/AKT pathway via targeting miR-370-3p.
    Immunopharmacology and immunotoxicology, 2021, Volume: 43, Issue:6

    Topics: Adult; Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cell Surviva

2021
Silencing lncRNA LINC01410 suppresses cell viability yet promotes apoptosis and sensitivity to temozolomide in glioblastoma cells by inactivating PTEN/AKT pathway via targeting miR-370-3p.
    Immunopharmacology and immunotoxicology, 2021, Volume: 43, Issue:6

    Topics: Adult; Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cell Surviva

2021
Silencing lncRNA LINC01410 suppresses cell viability yet promotes apoptosis and sensitivity to temozolomide in glioblastoma cells by inactivating PTEN/AKT pathway via targeting miR-370-3p.
    Immunopharmacology and immunotoxicology, 2021, Volume: 43, Issue:6

    Topics: Adult; Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cell Surviva

2021
Cytoprotective agent troxipide-cyanine dye conjugate with cytotoxic and antiproliferative activity in patient-derived glioblastoma cell lines.
    Bioorganic & medicinal chemistry letters, 2021, 10-15, Volume: 50

    Topics: Antineoplastic Agents; Brain Neoplasms; Carbocyanines; Cell Line, Tumor; Cell Proliferation; Cell Su

2021
Cytoprotective agent troxipide-cyanine dye conjugate with cytotoxic and antiproliferative activity in patient-derived glioblastoma cell lines.
    Bioorganic & medicinal chemistry letters, 2021, 10-15, Volume: 50

    Topics: Antineoplastic Agents; Brain Neoplasms; Carbocyanines; Cell Line, Tumor; Cell Proliferation; Cell Su

2021
Cytoprotective agent troxipide-cyanine dye conjugate with cytotoxic and antiproliferative activity in patient-derived glioblastoma cell lines.
    Bioorganic & medicinal chemistry letters, 2021, 10-15, Volume: 50

    Topics: Antineoplastic Agents; Brain Neoplasms; Carbocyanines; Cell Line, Tumor; Cell Proliferation; Cell Su

2021
The Combined Treatment with Chemotherapeutic Agents and the Dualsteric Muscarinic Agonist Iper-8-Naphthalimide Affects Drug Resistance in Glioblastoma Stem Cells.
    Cells, 2021, 07-24, Volume: 10, Issue:8

    Topics: Antineoplastic Combined Chemotherapy Protocols; ATP-Binding Cassette Transporters; Brain Neoplasms;

2021
The Combined Treatment with Chemotherapeutic Agents and the Dualsteric Muscarinic Agonist Iper-8-Naphthalimide Affects Drug Resistance in Glioblastoma Stem Cells.
    Cells, 2021, 07-24, Volume: 10, Issue:8

    Topics: Antineoplastic Combined Chemotherapy Protocols; ATP-Binding Cassette Transporters; Brain Neoplasms;

2021
The Combined Treatment with Chemotherapeutic Agents and the Dualsteric Muscarinic Agonist Iper-8-Naphthalimide Affects Drug Resistance in Glioblastoma Stem Cells.
    Cells, 2021, 07-24, Volume: 10, Issue:8

    Topics: Antineoplastic Combined Chemotherapy Protocols; ATP-Binding Cassette Transporters; Brain Neoplasms;

2021
Alkylaminophenol and GPR17 Agonist for Glioblastoma Therapy: A Combinational Approach for Enhanced Cell Death Activity.
    Cells, 2021, 08-03, Volume: 10, Issue:8

    Topics: Animals; Antineoplastic Agents; Apoptosis; Brain Neoplasms; Calcium; Caspase 3; Cell Line, Tumor; Ce

2021
Alkylaminophenol and GPR17 Agonist for Glioblastoma Therapy: A Combinational Approach for Enhanced Cell Death Activity.
    Cells, 2021, 08-03, Volume: 10, Issue:8

    Topics: Animals; Antineoplastic Agents; Apoptosis; Brain Neoplasms; Calcium; Caspase 3; Cell Line, Tumor; Ce

2021
Alkylaminophenol and GPR17 Agonist for Glioblastoma Therapy: A Combinational Approach for Enhanced Cell Death Activity.
    Cells, 2021, 08-03, Volume: 10, Issue:8

    Topics: Animals; Antineoplastic Agents; Apoptosis; Brain Neoplasms; Calcium; Caspase 3; Cell Line, Tumor; Ce

2021
Proton therapy for newly diagnosed glioblastoma: more room for investigation.
    Neuro-oncology, 2021, 11-02, Volume: 23, Issue:11

    Topics: Brain Neoplasms; Glioblastoma; Humans; Proton Therapy; Temozolomide

2021
Proton therapy for newly diagnosed glioblastoma: more room for investigation.
    Neuro-oncology, 2021, 11-02, Volume: 23, Issue:11

    Topics: Brain Neoplasms; Glioblastoma; Humans; Proton Therapy; Temozolomide

2021
Proton therapy for newly diagnosed glioblastoma: more room for investigation.
    Neuro-oncology, 2021, 11-02, Volume: 23, Issue:11

    Topics: Brain Neoplasms; Glioblastoma; Humans; Proton Therapy; Temozolomide

2021
Answer to the comment of Hai Lu et al. regarding "Hepatotoxicity by combination treatment of temozolomide, artesunate and Chinese herbs in a glioblastoma multiforme patient: case report and review of the literature. Arch Toxicol (2016)".
    Archives of toxicology, 2017, Volume: 91, Issue:6

    Topics: Artemisinins; Artesunate; Brain Neoplasms; Chemical and Drug Induced Liver Injury; Dacarbazine; Glio

2017
Answer to the comment of Hai Lu et al. regarding "Hepatotoxicity by combination treatment of temozolomide, artesunate and Chinese herbs in a glioblastoma multiforme patient: case report and review of the literature. Arch Toxicol (2016)".
    Archives of toxicology, 2017, Volume: 91, Issue:6

    Topics: Artemisinins; Artesunate; Brain Neoplasms; Chemical and Drug Induced Liver Injury; Dacarbazine; Glio

2017
Answer to the comment of Hai Lu et al. regarding "Hepatotoxicity by combination treatment of temozolomide, artesunate and Chinese herbs in a glioblastoma multiforme patient: case report and review of the literature. Arch Toxicol (2016)".
    Archives of toxicology, 2017, Volume: 91, Issue:6

    Topics: Artemisinins; Artesunate; Brain Neoplasms; Chemical and Drug Induced Liver Injury; Dacarbazine; Glio

2017
The allosteric AKT inhibitor MK2206 shows a synergistic interaction with chemotherapy and radiotherapy in glioblastoma spheroid cultures.
    BMC cancer, 2017, 03-21, Volume: 17, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Blotting, Western; Brain Neoplasms; Cell Line, Tumor; Cell Prolif

2017
The allosteric AKT inhibitor MK2206 shows a synergistic interaction with chemotherapy and radiotherapy in glioblastoma spheroid cultures.
    BMC cancer, 2017, 03-21, Volume: 17, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Blotting, Western; Brain Neoplasms; Cell Line, Tumor; Cell Prolif

2017
The allosteric AKT inhibitor MK2206 shows a synergistic interaction with chemotherapy and radiotherapy in glioblastoma spheroid cultures.
    BMC cancer, 2017, 03-21, Volume: 17, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Blotting, Western; Brain Neoplasms; Cell Line, Tumor; Cell Prolif

2017
MiR-223/PAX6 Axis Regulates Glioblastoma Stem Cell Proliferation and the Chemo Resistance to TMZ via Regulating PI3K/Akt Pathway.
    Journal of cellular biochemistry, 2017, Volume: 118, Issue:10

    Topics: Brain Neoplasms; Cell Proliferation; Dacarbazine; Drug Resistance, Neoplasm; Female; Glioblastoma; H

2017
MiR-223/PAX6 Axis Regulates Glioblastoma Stem Cell Proliferation and the Chemo Resistance to TMZ via Regulating PI3K/Akt Pathway.
    Journal of cellular biochemistry, 2017, Volume: 118, Issue:10

    Topics: Brain Neoplasms; Cell Proliferation; Dacarbazine; Drug Resistance, Neoplasm; Female; Glioblastoma; H

2017
MiR-223/PAX6 Axis Regulates Glioblastoma Stem Cell Proliferation and the Chemo Resistance to TMZ via Regulating PI3K/Akt Pathway.
    Journal of cellular biochemistry, 2017, Volume: 118, Issue:10

    Topics: Brain Neoplasms; Cell Proliferation; Dacarbazine; Drug Resistance, Neoplasm; Female; Glioblastoma; H

2017
Tumortropic adipose-derived stem cells carrying smart nanotherapeutics for targeted delivery and dual-modality therapy of orthotopic glioblastoma.
    Journal of controlled release : official journal of the Controlled Release Society, 2017, 05-28, Volume: 254

    Topics: Adipocytes; Animals; Antineoplastic Agents; Biological Transport; Blood-Brain Barrier; Brain Neoplas

2017
Tumortropic adipose-derived stem cells carrying smart nanotherapeutics for targeted delivery and dual-modality therapy of orthotopic glioblastoma.
    Journal of controlled release : official journal of the Controlled Release Society, 2017, 05-28, Volume: 254

    Topics: Adipocytes; Animals; Antineoplastic Agents; Biological Transport; Blood-Brain Barrier; Brain Neoplas

2017
Tumortropic adipose-derived stem cells carrying smart nanotherapeutics for targeted delivery and dual-modality therapy of orthotopic glioblastoma.
    Journal of controlled release : official journal of the Controlled Release Society, 2017, 05-28, Volume: 254

    Topics: Adipocytes; Animals; Antineoplastic Agents; Biological Transport; Blood-Brain Barrier; Brain Neoplas

2017
Treatment strategy and IDH status improve nomogram validity in newly diagnosed GBM patients.
    Neuro-oncology, 2017, 05-01, Volume: 19, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Asian People; Brain Neoplasms; Ch

2017
Treatment strategy and IDH status improve nomogram validity in newly diagnosed GBM patients.
    Neuro-oncology, 2017, 05-01, Volume: 19, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Asian People; Brain Neoplasms; Ch

2017
Treatment strategy and IDH status improve nomogram validity in newly diagnosed GBM patients.
    Neuro-oncology, 2017, 05-01, Volume: 19, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Asian People; Brain Neoplasms; Ch

2017
Temozolomide-Mediated Apoptotic Death Is Improved by Thymoquinone in U87MG Cell Line.
    Cancer investigation, 2017, Apr-21, Volume: 35, Issue:4

    Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Benzoquinones; Brain Neoplasms; Cell Line

2017
Temozolomide-Mediated Apoptotic Death Is Improved by Thymoquinone in U87MG Cell Line.
    Cancer investigation, 2017, Apr-21, Volume: 35, Issue:4

    Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Benzoquinones; Brain Neoplasms; Cell Line

2017
Temozolomide-Mediated Apoptotic Death Is Improved by Thymoquinone in U87MG Cell Line.
    Cancer investigation, 2017, Apr-21, Volume: 35, Issue:4

    Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Benzoquinones; Brain Neoplasms; Cell Line

2017
Lithium enhances the antitumour effect of temozolomide against TP53 wild-type glioblastoma cells via NFAT1/FasL signalling.
    British journal of cancer, 2017, May-09, Volume: 116, Issue:10

    Topics: Aged; Animals; Antibodies, Neutralizing; Antineoplastic Combined Chemotherapy Protocols; Apoptosis;

2017
Lithium enhances the antitumour effect of temozolomide against TP53 wild-type glioblastoma cells via NFAT1/FasL signalling.
    British journal of cancer, 2017, May-09, Volume: 116, Issue:10

    Topics: Aged; Animals; Antibodies, Neutralizing; Antineoplastic Combined Chemotherapy Protocols; Apoptosis;

2017
Lithium enhances the antitumour effect of temozolomide against TP53 wild-type glioblastoma cells via NFAT1/FasL signalling.
    British journal of cancer, 2017, May-09, Volume: 116, Issue:10

    Topics: Aged; Animals; Antibodies, Neutralizing; Antineoplastic Combined Chemotherapy Protocols; Apoptosis;

2017
Management and Survival Patterns of Patients with Gliomatosis Cerebri: A SEER-Based Analysis.
    World neurosurgery, 2017, Volume: 103

    Topics: Adult; Age Factors; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Astrocytoma; Brain N

2017
Management and Survival Patterns of Patients with Gliomatosis Cerebri: A SEER-Based Analysis.
    World neurosurgery, 2017, Volume: 103

    Topics: Adult; Age Factors; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Astrocytoma; Brain N

2017
Management and Survival Patterns of Patients with Gliomatosis Cerebri: A SEER-Based Analysis.
    World neurosurgery, 2017, Volume: 103

    Topics: Adult; Age Factors; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Astrocytoma; Brain N

2017
Is more better? The impact of extended adjuvant temozolomide in newly diagnosed glioblastoma: a secondary analysis of EORTC and NRG Oncology/RTOG.
    Neuro-oncology, 2017, Aug-01, Volume: 19, Issue:8

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modalit

2017
Is more better? The impact of extended adjuvant temozolomide in newly diagnosed glioblastoma: a secondary analysis of EORTC and NRG Oncology/RTOG.
    Neuro-oncology, 2017, Aug-01, Volume: 19, Issue:8

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modalit

2017
Is more better? The impact of extended adjuvant temozolomide in newly diagnosed glioblastoma: a secondary analysis of EORTC and NRG Oncology/RTOG.
    Neuro-oncology, 2017, Aug-01, Volume: 19, Issue:8

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modalit

2017
Dual bioluminescence and near-infrared fluorescence monitoring to evaluate spherical nucleic acid nanoconjugate activity in vivo.
    Proceedings of the National Academy of Sciences of the United States of America, 2017, 04-18, Volume: 114, Issue:16

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; DNA Modification Methylase

2017
Dual bioluminescence and near-infrared fluorescence monitoring to evaluate spherical nucleic acid nanoconjugate activity in vivo.
    Proceedings of the National Academy of Sciences of the United States of America, 2017, 04-18, Volume: 114, Issue:16

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; DNA Modification Methylase

2017
Dual bioluminescence and near-infrared fluorescence monitoring to evaluate spherical nucleic acid nanoconjugate activity in vivo.
    Proceedings of the National Academy of Sciences of the United States of America, 2017, 04-18, Volume: 114, Issue:16

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; DNA Modification Methylase

2017
Mustard-inspired delivery shuttle for enhanced blood-brain barrier penetration and effective drug delivery in glioma therapy.
    Biomaterials science, 2017, May-02, Volume: 5, Issue:5

    Topics: Animals; Antineoplastic Agents, Alkylating; Biological Transport; Blood-Brain Barrier; Brain Neoplas

2017
Mustard-inspired delivery shuttle for enhanced blood-brain barrier penetration and effective drug delivery in glioma therapy.
    Biomaterials science, 2017, May-02, Volume: 5, Issue:5

    Topics: Animals; Antineoplastic Agents, Alkylating; Biological Transport; Blood-Brain Barrier; Brain Neoplas

2017
Mustard-inspired delivery shuttle for enhanced blood-brain barrier penetration and effective drug delivery in glioma therapy.
    Biomaterials science, 2017, May-02, Volume: 5, Issue:5

    Topics: Animals; Antineoplastic Agents, Alkylating; Biological Transport; Blood-Brain Barrier; Brain Neoplas

2017
Sex as a biological variable in response to temozolomide.
    Neuro-oncology, 2017, 06-01, Volume: 19, Issue:6

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Glioblastoma; Mice; Sex Factors; Surviv

2017
Sex as a biological variable in response to temozolomide.
    Neuro-oncology, 2017, 06-01, Volume: 19, Issue:6

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Glioblastoma; Mice; Sex Factors; Surviv

2017
Sex as a biological variable in response to temozolomide.
    Neuro-oncology, 2017, 06-01, Volume: 19, Issue:6

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Glioblastoma; Mice; Sex Factors; Surviv

2017
β-Asarone promotes Temozolomide's entry into glioma cells and decreases the expression of P-glycoprotein and MDR1.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2017, Volume: 90

    Topics: Allylbenzene Derivatives; Animals; Anisoles; Antineoplastic Agents, Alkylating; ATP Binding Cassette

2017
β-Asarone promotes Temozolomide's entry into glioma cells and decreases the expression of P-glycoprotein and MDR1.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2017, Volume: 90

    Topics: Allylbenzene Derivatives; Animals; Anisoles; Antineoplastic Agents, Alkylating; ATP Binding Cassette

2017
β-Asarone promotes Temozolomide's entry into glioma cells and decreases the expression of P-glycoprotein and MDR1.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2017, Volume: 90

    Topics: Allylbenzene Derivatives; Animals; Anisoles; Antineoplastic Agents, Alkylating; ATP Binding Cassette

2017
Influence of incidental radiation dose in the subventricular zone on survival in patients with glioblastoma multiforme treated with surgery, radiotherapy, and temozolomide.
    Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico, 2017, Volume: 19, Issue:10

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Female;

2017
Influence of incidental radiation dose in the subventricular zone on survival in patients with glioblastoma multiforme treated with surgery, radiotherapy, and temozolomide.
    Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico, 2017, Volume: 19, Issue:10

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Female;

2017
Influence of incidental radiation dose in the subventricular zone on survival in patients with glioblastoma multiforme treated with surgery, radiotherapy, and temozolomide.
    Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico, 2017, Volume: 19, Issue:10

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Female;

2017
Dual treatment with shikonin and temozolomide reduces glioblastoma tumor growth, migration and glial-to-mesenchymal transition.
    Cellular oncology (Dordrecht), 2017, Volume: 40, Issue:3

    Topics: Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Cell Line, Tumor; Cell Movement; Ce

2017
Dual treatment with shikonin and temozolomide reduces glioblastoma tumor growth, migration and glial-to-mesenchymal transition.
    Cellular oncology (Dordrecht), 2017, Volume: 40, Issue:3

    Topics: Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Cell Line, Tumor; Cell Movement; Ce

2017
Dual treatment with shikonin and temozolomide reduces glioblastoma tumor growth, migration and glial-to-mesenchymal transition.
    Cellular oncology (Dordrecht), 2017, Volume: 40, Issue:3

    Topics: Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Cell Line, Tumor; Cell Movement; Ce

2017
Differential pro-apoptotic effects of synthetic 4-thiazolidinone derivative Les-3288, doxorubicin and temozolomide in human glioma U251 cells.
    Croatian medical journal, 2017, Apr-14, Volume: 58, Issue:2

    Topics: Antineoplastic Agents; Apoptosis; Blood-Brain Barrier; Brain Neoplasms; Caspase 3; Cell Line, Tumor;

2017
Differential pro-apoptotic effects of synthetic 4-thiazolidinone derivative Les-3288, doxorubicin and temozolomide in human glioma U251 cells.
    Croatian medical journal, 2017, Apr-14, Volume: 58, Issue:2

    Topics: Antineoplastic Agents; Apoptosis; Blood-Brain Barrier; Brain Neoplasms; Caspase 3; Cell Line, Tumor;

2017
Differential pro-apoptotic effects of synthetic 4-thiazolidinone derivative Les-3288, doxorubicin and temozolomide in human glioma U251 cells.
    Croatian medical journal, 2017, Apr-14, Volume: 58, Issue:2

    Topics: Antineoplastic Agents; Apoptosis; Blood-Brain Barrier; Brain Neoplasms; Caspase 3; Cell Line, Tumor;

2017
Correlations of MGMT genetic polymorphisms with temozolomide resistance and prognosis of patients with malignant gliomas: a population-based study in China.
    Cancer gene therapy, 2017, Volume: 24, Issue:5

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Asian People; Brain Neoplasms; China; Dacarbazine; D

2017
Correlations of MGMT genetic polymorphisms with temozolomide resistance and prognosis of patients with malignant gliomas: a population-based study in China.
    Cancer gene therapy, 2017, Volume: 24, Issue:5

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Asian People; Brain Neoplasms; China; Dacarbazine; D

2017
Correlations of MGMT genetic polymorphisms with temozolomide resistance and prognosis of patients with malignant gliomas: a population-based study in China.
    Cancer gene therapy, 2017, Volume: 24, Issue:5

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Asian People; Brain Neoplasms; China; Dacarbazine; D

2017
Promoting oligodendroglial-oriented differentiation of glioma stem cell: a repurposing of quetiapine for the treatment of malignant glioma.
    Oncotarget, 2017, Jun-06, Volume: 8, Issue:23

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Cell Differentiation; Cell

2017
Promoting oligodendroglial-oriented differentiation of glioma stem cell: a repurposing of quetiapine for the treatment of malignant glioma.
    Oncotarget, 2017, Jun-06, Volume: 8, Issue:23

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Cell Differentiation; Cell

2017
Promoting oligodendroglial-oriented differentiation of glioma stem cell: a repurposing of quetiapine for the treatment of malignant glioma.
    Oncotarget, 2017, Jun-06, Volume: 8, Issue:23

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Cell Differentiation; Cell

2017
Tumor microtubes convey resistance to surgical lesions and chemotherapy in gliomas.
    Neuro-oncology, 2017, Oct-01, Volume: 19, Issue:10

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; D

2017
Tumor microtubes convey resistance to surgical lesions and chemotherapy in gliomas.
    Neuro-oncology, 2017, Oct-01, Volume: 19, Issue:10

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; D

2017
Tumor microtubes convey resistance to surgical lesions and chemotherapy in gliomas.
    Neuro-oncology, 2017, Oct-01, Volume: 19, Issue:10

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; D

2017
The stem cell/cancer stem cell marker ALDH1A3 regulates the expression of the survival factor tissue transglutaminase, in mesenchymal glioma stem cells.
    Oncotarget, 2017, Apr-04, Volume: 8, Issue:14

    Topics: Aldehyde Oxidoreductases; Biomarkers, Tumor; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation;

2017
The stem cell/cancer stem cell marker ALDH1A3 regulates the expression of the survival factor tissue transglutaminase, in mesenchymal glioma stem cells.
    Oncotarget, 2017, Apr-04, Volume: 8, Issue:14

    Topics: Aldehyde Oxidoreductases; Biomarkers, Tumor; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation;

2017
The stem cell/cancer stem cell marker ALDH1A3 regulates the expression of the survival factor tissue transglutaminase, in mesenchymal glioma stem cells.
    Oncotarget, 2017, Apr-04, Volume: 8, Issue:14

    Topics: Aldehyde Oxidoreductases; Biomarkers, Tumor; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation;

2017
MiR-198 enhances temozolomide sensitivity in glioblastoma by targeting MGMT.
    Journal of neuro-oncology, 2017, Volume: 133, Issue:1

    Topics: Adult; Aged; Animals; Antineoplastic Agents, Alkylating; Astrocytes; Brain Neoplasms; Cell Line, Tum

2017
MiR-198 enhances temozolomide sensitivity in glioblastoma by targeting MGMT.
    Journal of neuro-oncology, 2017, Volume: 133, Issue:1

    Topics: Adult; Aged; Animals; Antineoplastic Agents, Alkylating; Astrocytes; Brain Neoplasms; Cell Line, Tum

2017
MiR-198 enhances temozolomide sensitivity in glioblastoma by targeting MGMT.
    Journal of neuro-oncology, 2017, Volume: 133, Issue:1

    Topics: Adult; Aged; Animals; Antineoplastic Agents, Alkylating; Astrocytes; Brain Neoplasms; Cell Line, Tum

2017
Biological activity of tumor-treating fields in preclinical glioma models.
    Cell death & disease, 2017, 04-20, Volume: 8, Issue:4

    Topics: Apoptosis; Brain Neoplasms; Caspases; Cell Cycle; Cell Line, Tumor; Cell Movement; Cell Survival; Da

2017
Biological activity of tumor-treating fields in preclinical glioma models.
    Cell death & disease, 2017, 04-20, Volume: 8, Issue:4

    Topics: Apoptosis; Brain Neoplasms; Caspases; Cell Cycle; Cell Line, Tumor; Cell Movement; Cell Survival; Da

2017
Biological activity of tumor-treating fields in preclinical glioma models.
    Cell death & disease, 2017, 04-20, Volume: 8, Issue:4

    Topics: Apoptosis; Brain Neoplasms; Caspases; Cell Cycle; Cell Line, Tumor; Cell Movement; Cell Survival; Da

2017
IDH1 R132H mutation regulates glioma chemosensitivity through Nrf2 pathway.
    Oncotarget, 2017, Apr-25, Volume: 8, Issue:17

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Dacarbazine; Drug Resistance,

2017
IDH1 R132H mutation regulates glioma chemosensitivity through Nrf2 pathway.
    Oncotarget, 2017, Apr-25, Volume: 8, Issue:17

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Dacarbazine; Drug Resistance,

2017
IDH1 R132H mutation regulates glioma chemosensitivity through Nrf2 pathway.
    Oncotarget, 2017, Apr-25, Volume: 8, Issue:17

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Dacarbazine; Drug Resistance,

2017
A case of glioblastoma resected immediately after administering bevacizumab: consideration on histopathological findings and safety of surgery.
    Brain tumor pathology, 2017, Volume: 34, Issue:2

    Topics: Adult; Bevacizumab; Brain Neoplasms; Combined Modality Therapy; Craniotomy; Dacarbazine; Humans; Int

2017
A case of glioblastoma resected immediately after administering bevacizumab: consideration on histopathological findings and safety of surgery.
    Brain tumor pathology, 2017, Volume: 34, Issue:2

    Topics: Adult; Bevacizumab; Brain Neoplasms; Combined Modality Therapy; Craniotomy; Dacarbazine; Humans; Int

2017
A case of glioblastoma resected immediately after administering bevacizumab: consideration on histopathological findings and safety of surgery.
    Brain tumor pathology, 2017, Volume: 34, Issue:2

    Topics: Adult; Bevacizumab; Brain Neoplasms; Combined Modality Therapy; Craniotomy; Dacarbazine; Humans; Int

2017
Prognostic implications of the subcellular localization of survivin in glioblastomas treated with radiotherapy plus concomitant and adjuvant temozolomide.
    Journal of neurosurgery, 2018, Volume: 128, Issue:3

    Topics: Aged; Antineoplastic Agents, Alkylating; Brain; Brain Neoplasms; Cell Nucleus; Chemotherapy, Adjuvan

2018
Prognostic implications of the subcellular localization of survivin in glioblastomas treated with radiotherapy plus concomitant and adjuvant temozolomide.
    Journal of neurosurgery, 2018, Volume: 128, Issue:3

    Topics: Aged; Antineoplastic Agents, Alkylating; Brain; Brain Neoplasms; Cell Nucleus; Chemotherapy, Adjuvan

2018
Prognostic implications of the subcellular localization of survivin in glioblastomas treated with radiotherapy plus concomitant and adjuvant temozolomide.
    Journal of neurosurgery, 2018, Volume: 128, Issue:3

    Topics: Aged; Antineoplastic Agents, Alkylating; Brain; Brain Neoplasms; Cell Nucleus; Chemotherapy, Adjuvan

2018
Small molecules targeting histone demethylase genes (KDMs) inhibit growth of temozolomide-resistant glioblastoma cells.
    Oncotarget, 2017, May-23, Volume: 8, Issue:21

    Topics: Aminopyridines; Animals; Blood-Brain Barrier; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation;

2017
Small molecules targeting histone demethylase genes (KDMs) inhibit growth of temozolomide-resistant glioblastoma cells.
    Oncotarget, 2017, May-23, Volume: 8, Issue:21

    Topics: Aminopyridines; Animals; Blood-Brain Barrier; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation;

2017
Small molecules targeting histone demethylase genes (KDMs) inhibit growth of temozolomide-resistant glioblastoma cells.
    Oncotarget, 2017, May-23, Volume: 8, Issue:21

    Topics: Aminopyridines; Animals; Blood-Brain Barrier; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation;

2017
Expression and function of ABCG2 and XIAP in glioblastomas.
    Journal of neuro-oncology, 2017, Volume: 133, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Animals; Antineoplastic Agents; ATP Binding Cassette Transporter, Su

2017
Expression and function of ABCG2 and XIAP in glioblastomas.
    Journal of neuro-oncology, 2017, Volume: 133, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Animals; Antineoplastic Agents; ATP Binding Cassette Transporter, Su

2017
Expression and function of ABCG2 and XIAP in glioblastomas.
    Journal of neuro-oncology, 2017, Volume: 133, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Animals; Antineoplastic Agents; ATP Binding Cassette Transporter, Su

2017
Recurrence Pattern Analysis of Primary Glioblastoma.
    World neurosurgery, 2017, Volume: 103

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherap

2017
Recurrence Pattern Analysis of Primary Glioblastoma.
    World neurosurgery, 2017, Volume: 103

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherap

2017
Recurrence Pattern Analysis of Primary Glioblastoma.
    World neurosurgery, 2017, Volume: 103

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherap

2017
EMAP-II sensitize U87MG and glioma stem-like cells to temozolomide via induction of autophagy-mediated cell death and G2/M arrest.
    Cell cycle (Georgetown, Tex.), 2017, Jun-03, Volume: 16, Issue:11

    Topics: Apoptosis; Autophagy; Brain Neoplasms; Cell Cycle Checkpoints; Cell Line, Tumor; Cytokines; Dacarbaz

2017
EMAP-II sensitize U87MG and glioma stem-like cells to temozolomide via induction of autophagy-mediated cell death and G2/M arrest.
    Cell cycle (Georgetown, Tex.), 2017, Jun-03, Volume: 16, Issue:11

    Topics: Apoptosis; Autophagy; Brain Neoplasms; Cell Cycle Checkpoints; Cell Line, Tumor; Cytokines; Dacarbaz

2017
EMAP-II sensitize U87MG and glioma stem-like cells to temozolomide via induction of autophagy-mediated cell death and G2/M arrest.
    Cell cycle (Georgetown, Tex.), 2017, Jun-03, Volume: 16, Issue:11

    Topics: Apoptosis; Autophagy; Brain Neoplasms; Cell Cycle Checkpoints; Cell Line, Tumor; Cytokines; Dacarbaz

2017
Depletion of adult neurogenesis using the chemotherapy drug temozolomide in mice induces behavioural and biological changes relevant to depression.
    Translational psychiatry, 2017, 04-25, Volume: 7, Issue:4

    Topics: Animals; Antineoplastic Agents, Alkylating; Behavior, Animal; Biochemical Phenomena; Brain; Brain Ne

2017
Depletion of adult neurogenesis using the chemotherapy drug temozolomide in mice induces behavioural and biological changes relevant to depression.
    Translational psychiatry, 2017, 04-25, Volume: 7, Issue:4

    Topics: Animals; Antineoplastic Agents, Alkylating; Behavior, Animal; Biochemical Phenomena; Brain; Brain Ne

2017
Depletion of adult neurogenesis using the chemotherapy drug temozolomide in mice induces behavioural and biological changes relevant to depression.
    Translational psychiatry, 2017, 04-25, Volume: 7, Issue:4

    Topics: Animals; Antineoplastic Agents, Alkylating; Behavior, Animal; Biochemical Phenomena; Brain; Brain Ne

2017
Downregulation of β-arrestin 1 suppresses glioblastoma cell malignant progression vis inhibition of Src signaling.
    Experimental cell research, 2017, 08-01, Volume: 357, Issue:1

    Topics: Animals; beta-Arrestin 1; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Dacarbazine; Diseas

2017
Downregulation of β-arrestin 1 suppresses glioblastoma cell malignant progression vis inhibition of Src signaling.
    Experimental cell research, 2017, 08-01, Volume: 357, Issue:1

    Topics: Animals; beta-Arrestin 1; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Dacarbazine; Diseas

2017
Downregulation of β-arrestin 1 suppresses glioblastoma cell malignant progression vis inhibition of Src signaling.
    Experimental cell research, 2017, 08-01, Volume: 357, Issue:1

    Topics: Animals; beta-Arrestin 1; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Dacarbazine; Diseas

2017
Aspirin inhibits the SHH/GLI1 signaling pathway and sensitizes malignant glioma cells to temozolomide therapy.
    Aging, 2017, Volume: 9, Issue:4

    Topics: Antineoplastic Agents, Alkylating; Apoptosis; Aspirin; Brain Neoplasms; Cell Line, Tumor; Dacarbazin

2017
Aspirin inhibits the SHH/GLI1 signaling pathway and sensitizes malignant glioma cells to temozolomide therapy.
    Aging, 2017, Volume: 9, Issue:4

    Topics: Antineoplastic Agents, Alkylating; Apoptosis; Aspirin; Brain Neoplasms; Cell Line, Tumor; Dacarbazin

2017
Aspirin inhibits the SHH/GLI1 signaling pathway and sensitizes malignant glioma cells to temozolomide therapy.
    Aging, 2017, Volume: 9, Issue:4

    Topics: Antineoplastic Agents, Alkylating; Apoptosis; Aspirin; Brain Neoplasms; Cell Line, Tumor; Dacarbazin

2017
Repositioning chlorpromazine for treating chemoresistant glioma through the inhibition of cytochrome c oxidase bearing the COX4-1 regulatory subunit.
    Oncotarget, 2017, Jun-06, Volume: 8, Issue:23

    Topics: Animals; Antineoplastic Agents, Alkylating; Antipsychotic Agents; Brain Neoplasms; Cattle; Cell Line

2017
Repositioning chlorpromazine for treating chemoresistant glioma through the inhibition of cytochrome c oxidase bearing the COX4-1 regulatory subunit.
    Oncotarget, 2017, Jun-06, Volume: 8, Issue:23

    Topics: Animals; Antineoplastic Agents, Alkylating; Antipsychotic Agents; Brain Neoplasms; Cattle; Cell Line

2017
Repositioning chlorpromazine for treating chemoresistant glioma through the inhibition of cytochrome c oxidase bearing the COX4-1 regulatory subunit.
    Oncotarget, 2017, Jun-06, Volume: 8, Issue:23

    Topics: Animals; Antineoplastic Agents, Alkylating; Antipsychotic Agents; Brain Neoplasms; Cattle; Cell Line

2017
Long-term benefit of intra-arterial bevacizumab for recurrent glioblastoma.
    Journal of experimental therapeutics & oncology, 2017, Volume: 12, Issue:1

    Topics: Adult; Bevacizumab; Blood-Brain Barrier; Brain Neoplasms; Dacarbazine; Glioblastoma; Humans; Male; N

2017
Long-term benefit of intra-arterial bevacizumab for recurrent glioblastoma.
    Journal of experimental therapeutics & oncology, 2017, Volume: 12, Issue:1

    Topics: Adult; Bevacizumab; Blood-Brain Barrier; Brain Neoplasms; Dacarbazine; Glioblastoma; Humans; Male; N

2017
Long-term benefit of intra-arterial bevacizumab for recurrent glioblastoma.
    Journal of experimental therapeutics & oncology, 2017, Volume: 12, Issue:1

    Topics: Adult; Bevacizumab; Blood-Brain Barrier; Brain Neoplasms; Dacarbazine; Glioblastoma; Humans; Male; N

2017
Developing an Algorithm for Optimizing Care of Elderly Patients With Glioblastoma.
    Neurosurgery, 2018, Jan-01, Volume: 82, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Algorithms; Antineoplastic Agents, Alkylating; Brain Neoplasms; Daca

2018
Developing an Algorithm for Optimizing Care of Elderly Patients With Glioblastoma.
    Neurosurgery, 2018, Jan-01, Volume: 82, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Algorithms; Antineoplastic Agents, Alkylating; Brain Neoplasms; Daca

2018
Developing an Algorithm for Optimizing Care of Elderly Patients With Glioblastoma.
    Neurosurgery, 2018, Jan-01, Volume: 82, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Algorithms; Antineoplastic Agents, Alkylating; Brain Neoplasms; Daca

2018
Combination therapy with micellarized cyclopamine and temozolomide attenuate glioblastoma growth through Gli1 down-regulation.
    Oncotarget, 2017, Jun-27, Volume: 8, Issue:26

    Topics: Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cell Survival; Daca

2017
Combination therapy with micellarized cyclopamine and temozolomide attenuate glioblastoma growth through Gli1 down-regulation.
    Oncotarget, 2017, Jun-27, Volume: 8, Issue:26

    Topics: Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cell Survival; Daca

2017
Combination therapy with micellarized cyclopamine and temozolomide attenuate glioblastoma growth through Gli1 down-regulation.
    Oncotarget, 2017, Jun-27, Volume: 8, Issue:26

    Topics: Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cell Survival; Daca

2017
MDM2 Degrades Deacetylated Nucleolin Through Ubiquitination to Promote Glioma Stem-Like Cell Enrichment for Chemotherapeutic Resistance.
    Molecular neurobiology, 2018, Volume: 55, Issue:4

    Topics: Acetylation; Brain Neoplasms; Cell Line, Tumor; Down-Regulation; Drug Resistance, Neoplasm; Gene Exp

2018
MDM2 Degrades Deacetylated Nucleolin Through Ubiquitination to Promote Glioma Stem-Like Cell Enrichment for Chemotherapeutic Resistance.
    Molecular neurobiology, 2018, Volume: 55, Issue:4

    Topics: Acetylation; Brain Neoplasms; Cell Line, Tumor; Down-Regulation; Drug Resistance, Neoplasm; Gene Exp

2018
MDM2 Degrades Deacetylated Nucleolin Through Ubiquitination to Promote Glioma Stem-Like Cell Enrichment for Chemotherapeutic Resistance.
    Molecular neurobiology, 2018, Volume: 55, Issue:4

    Topics: Acetylation; Brain Neoplasms; Cell Line, Tumor; Down-Regulation; Drug Resistance, Neoplasm; Gene Exp

2018
TREATMENT OF PROGRESSION OF DIFFUSE ASTROCYTOMA BY HERBAL MEDICINE: CASE REPORT.
    African journal of traditional, complementary, and alternative medicines : AJTCAM, 2016, Volume: 13, Issue:6

    Topics: Adult; Antineoplastic Agents; Astrocytoma; Brain Neoplasms; Combined Modality Therapy; Dacarbazine;

2016
TREATMENT OF PROGRESSION OF DIFFUSE ASTROCYTOMA BY HERBAL MEDICINE: CASE REPORT.
    African journal of traditional, complementary, and alternative medicines : AJTCAM, 2016, Volume: 13, Issue:6

    Topics: Adult; Antineoplastic Agents; Astrocytoma; Brain Neoplasms; Combined Modality Therapy; Dacarbazine;

2016
TREATMENT OF PROGRESSION OF DIFFUSE ASTROCYTOMA BY HERBAL MEDICINE: CASE REPORT.
    African journal of traditional, complementary, and alternative medicines : AJTCAM, 2016, Volume: 13, Issue:6

    Topics: Adult; Antineoplastic Agents; Astrocytoma; Brain Neoplasms; Combined Modality Therapy; Dacarbazine;

2016
Comparative analysis of the effects of a sphingosine kinase inhibitor to temozolomide and radiation treatment on glioblastoma cell lines.
    Cancer biology & therapy, 2017, 06-03, Volume: 18, Issue:6

    Topics: Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cell Survival; Chem

2017
Comparative analysis of the effects of a sphingosine kinase inhibitor to temozolomide and radiation treatment on glioblastoma cell lines.
    Cancer biology & therapy, 2017, 06-03, Volume: 18, Issue:6

    Topics: Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cell Survival; Chem

2017
Comparative analysis of the effects of a sphingosine kinase inhibitor to temozolomide and radiation treatment on glioblastoma cell lines.
    Cancer biology & therapy, 2017, 06-03, Volume: 18, Issue:6

    Topics: Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cell Survival; Chem

2017
Reversing glioma malignancy: a new look at the role of antidepressant drugs as adjuvant therapy for glioblastoma multiforme.
    Cancer chemotherapy and pharmacology, 2017, Volume: 79, Issue:6

    Topics: Antidepressive Agents; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Cell Su

2017
Reversing glioma malignancy: a new look at the role of antidepressant drugs as adjuvant therapy for glioblastoma multiforme.
    Cancer chemotherapy and pharmacology, 2017, Volume: 79, Issue:6

    Topics: Antidepressive Agents; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Cell Su

2017
Reversing glioma malignancy: a new look at the role of antidepressant drugs as adjuvant therapy for glioblastoma multiforme.
    Cancer chemotherapy and pharmacology, 2017, Volume: 79, Issue:6

    Topics: Antidepressive Agents; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Cell Su

2017
MiR-181b modulates chemosensitivity of glioblastoma multiforme cells to temozolomide by targeting the epidermal growth factor receptor.
    Journal of neuro-oncology, 2017, Volume: 133, Issue:3

    Topics: Animals; Antineoplastic Agents, Alkylating; Apoptosis; Brain; Brain Neoplasms; Cell Line, Tumor; Dac

2017
MiR-181b modulates chemosensitivity of glioblastoma multiforme cells to temozolomide by targeting the epidermal growth factor receptor.
    Journal of neuro-oncology, 2017, Volume: 133, Issue:3

    Topics: Animals; Antineoplastic Agents, Alkylating; Apoptosis; Brain; Brain Neoplasms; Cell Line, Tumor; Dac

2017
MiR-181b modulates chemosensitivity of glioblastoma multiforme cells to temozolomide by targeting the epidermal growth factor receptor.
    Journal of neuro-oncology, 2017, Volume: 133, Issue:3

    Topics: Animals; Antineoplastic Agents, Alkylating; Apoptosis; Brain; Brain Neoplasms; Cell Line, Tumor; Dac

2017
The redox couple avarol/avarone in the fight with malignant gliomas: the case study of U-251 MG cells.
    Natural product research, 2018, Volume: 32, Issue:5

    Topics: Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Cell Line, Tumor; Comet Assay; Cycl

2018
The redox couple avarol/avarone in the fight with malignant gliomas: the case study of U-251 MG cells.
    Natural product research, 2018, Volume: 32, Issue:5

    Topics: Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Cell Line, Tumor; Comet Assay; Cycl

2018
The redox couple avarol/avarone in the fight with malignant gliomas: the case study of U-251 MG cells.
    Natural product research, 2018, Volume: 32, Issue:5

    Topics: Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Cell Line, Tumor; Comet Assay; Cycl

2018
Establishment of a tumor sphere cell line from a metastatic brain neuroendocrine tumor.
    Medical molecular morphology, 2017, Volume: 50, Issue:4

    Topics: AC133 Antigen; Aged; Aldehyde Dehydrogenase; Animals; Antineoplastic Agents, Alkylating; Biomarkers,

2017
Establishment of a tumor sphere cell line from a metastatic brain neuroendocrine tumor.
    Medical molecular morphology, 2017, Volume: 50, Issue:4

    Topics: AC133 Antigen; Aged; Aldehyde Dehydrogenase; Animals; Antineoplastic Agents, Alkylating; Biomarkers,

2017
Establishment of a tumor sphere cell line from a metastatic brain neuroendocrine tumor.
    Medical molecular morphology, 2017, Volume: 50, Issue:4

    Topics: AC133 Antigen; Aged; Aldehyde Dehydrogenase; Animals; Antineoplastic Agents, Alkylating; Biomarkers,

2017
Defining optimal cutoff value of MGMT promoter methylation by ROC analysis for clinical setting in glioblastoma patients.
    Journal of neuro-oncology, 2017, Volume: 133, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Area Under Curve; Brain Neoplasms; CpG Islands; Dacarbazine; DNA

2017
Defining optimal cutoff value of MGMT promoter methylation by ROC analysis for clinical setting in glioblastoma patients.
    Journal of neuro-oncology, 2017, Volume: 133, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Area Under Curve; Brain Neoplasms; CpG Islands; Dacarbazine; DNA

2017
Defining optimal cutoff value of MGMT promoter methylation by ROC analysis for clinical setting in glioblastoma patients.
    Journal of neuro-oncology, 2017, Volume: 133, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Area Under Curve; Brain Neoplasms; CpG Islands; Dacarbazine; DNA

2017
A Survival Analysis with Identification of Prognostic Factors in a Series of 110 Patients with Newly Diagnosed Glioblastoma Before and After Introduction of the Stupp Regimen: A Single-Center Observational Study.
    World neurosurgery, 2017, Volume: 104

    Topics: Adult; Aged; Brain Neoplasms; Carmustine; Chemotherapy, Adjuvant; Combined Modality Therapy; Craniot

2017
A Survival Analysis with Identification of Prognostic Factors in a Series of 110 Patients with Newly Diagnosed Glioblastoma Before and After Introduction of the Stupp Regimen: A Single-Center Observational Study.
    World neurosurgery, 2017, Volume: 104

    Topics: Adult; Aged; Brain Neoplasms; Carmustine; Chemotherapy, Adjuvant; Combined Modality Therapy; Craniot

2017
A Survival Analysis with Identification of Prognostic Factors in a Series of 110 Patients with Newly Diagnosed Glioblastoma Before and After Introduction of the Stupp Regimen: A Single-Center Observational Study.
    World neurosurgery, 2017, Volume: 104

    Topics: Adult; Aged; Brain Neoplasms; Carmustine; Chemotherapy, Adjuvant; Combined Modality Therapy; Craniot

2017
Changes in tumor cell heterogeneity after chemotherapy treatment in a xenograft model of glioblastoma.
    Neuroscience, 2017, 07-25, Volume: 356

    Topics: Animals; Brain Neoplasms; Cell Line, Tumor; Dacarbazine; Disease Models, Animal; Glioblastoma; Heter

2017
Changes in tumor cell heterogeneity after chemotherapy treatment in a xenograft model of glioblastoma.
    Neuroscience, 2017, 07-25, Volume: 356

    Topics: Animals; Brain Neoplasms; Cell Line, Tumor; Dacarbazine; Disease Models, Animal; Glioblastoma; Heter

2017
Changes in tumor cell heterogeneity after chemotherapy treatment in a xenograft model of glioblastoma.
    Neuroscience, 2017, 07-25, Volume: 356

    Topics: Animals; Brain Neoplasms; Cell Line, Tumor; Dacarbazine; Disease Models, Animal; Glioblastoma; Heter

2017
Guanosine promotes cytotoxicity via adenosine receptors and induces apoptosis in temozolomide-treated A172 glioma cells.
    Purinergic signalling, 2017, Volume: 13, Issue:3

    Topics: Antineoplastic Agents, Alkylating; Apoptosis; Autophagy; Brain Neoplasms; Cell Line, Tumor; Cell Sur

2017
Guanosine promotes cytotoxicity via adenosine receptors and induces apoptosis in temozolomide-treated A172 glioma cells.
    Purinergic signalling, 2017, Volume: 13, Issue:3

    Topics: Antineoplastic Agents, Alkylating; Apoptosis; Autophagy; Brain Neoplasms; Cell Line, Tumor; Cell Sur

2017
Guanosine promotes cytotoxicity via adenosine receptors and induces apoptosis in temozolomide-treated A172 glioma cells.
    Purinergic signalling, 2017, Volume: 13, Issue:3

    Topics: Antineoplastic Agents, Alkylating; Apoptosis; Autophagy; Brain Neoplasms; Cell Line, Tumor; Cell Sur

2017
Impact of interim progression during the surgery-to-radiotherapy interval and its predictors in glioblastoma treated with temozolomide-based radiochemotherapy.
    Journal of neuro-oncology, 2017, Volume: 134, Issue:1

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Dacarbazine; Dis

2017
Impact of interim progression during the surgery-to-radiotherapy interval and its predictors in glioblastoma treated with temozolomide-based radiochemotherapy.
    Journal of neuro-oncology, 2017, Volume: 134, Issue:1

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Dacarbazine; Dis

2017
Impact of interim progression during the surgery-to-radiotherapy interval and its predictors in glioblastoma treated with temozolomide-based radiochemotherapy.
    Journal of neuro-oncology, 2017, Volume: 134, Issue:1

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Dacarbazine; Dis

2017
Front-line glioblastoma chemotherapeutic temozolomide is toxic to Trypanosoma brucei and potently enhances melarsoprol and eflornithine.
    Experimental parasitology, 2017, Volume: 178

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Drug Therapy, Combination; Eflornit

2017
Front-line glioblastoma chemotherapeutic temozolomide is toxic to Trypanosoma brucei and potently enhances melarsoprol and eflornithine.
    Experimental parasitology, 2017, Volume: 178

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Drug Therapy, Combination; Eflornit

2017
Front-line glioblastoma chemotherapeutic temozolomide is toxic to Trypanosoma brucei and potently enhances melarsoprol and eflornithine.
    Experimental parasitology, 2017, Volume: 178

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Drug Therapy, Combination; Eflornit

2017
Atorvastatin augments temozolomide's efficacy in glioblastoma via prenylation-dependent inhibition of Ras signaling.
    Biochemical and biophysical research communications, 2017, 07-29, Volume: 489, Issue:3

    Topics: Animals; Atorvastatin; Brain Neoplasms; Cell Proliferation; Cell Survival; Dacarbazine; Disease Mode

2017
Atorvastatin augments temozolomide's efficacy in glioblastoma via prenylation-dependent inhibition of Ras signaling.
    Biochemical and biophysical research communications, 2017, 07-29, Volume: 489, Issue:3

    Topics: Animals; Atorvastatin; Brain Neoplasms; Cell Proliferation; Cell Survival; Dacarbazine; Disease Mode

2017
Atorvastatin augments temozolomide's efficacy in glioblastoma via prenylation-dependent inhibition of Ras signaling.
    Biochemical and biophysical research communications, 2017, 07-29, Volume: 489, Issue:3

    Topics: Animals; Atorvastatin; Brain Neoplasms; Cell Proliferation; Cell Survival; Dacarbazine; Disease Mode

2017
Therapeutic targeting of chemoresistant and recurrent glioblastoma stem cells with a proapoptotic variant of oncolytic herpes simplex virus.
    International journal of cancer, 2017, 10-15, Volume: 141, Issue:8

    Topics: Animals; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cohort Studies; Dacarbazine; Drug Resistance,

2017
Therapeutic targeting of chemoresistant and recurrent glioblastoma stem cells with a proapoptotic variant of oncolytic herpes simplex virus.
    International journal of cancer, 2017, 10-15, Volume: 141, Issue:8

    Topics: Animals; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cohort Studies; Dacarbazine; Drug Resistance,

2017
Therapeutic targeting of chemoresistant and recurrent glioblastoma stem cells with a proapoptotic variant of oncolytic herpes simplex virus.
    International journal of cancer, 2017, 10-15, Volume: 141, Issue:8

    Topics: Animals; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cohort Studies; Dacarbazine; Drug Resistance,

2017
CBF1 is clinically prognostic and serves as a target to block cellular invasion and chemoresistance of EMT-like glioblastoma cells.
    British journal of cancer, 2017, Jun-27, Volume: 117, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Blotting, Western; Brain Neoplasms; Cell Line, Tumor; Cell Surviv

2017
CBF1 is clinically prognostic and serves as a target to block cellular invasion and chemoresistance of EMT-like glioblastoma cells.
    British journal of cancer, 2017, Jun-27, Volume: 117, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Blotting, Western; Brain Neoplasms; Cell Line, Tumor; Cell Surviv

2017
CBF1 is clinically prognostic and serves as a target to block cellular invasion and chemoresistance of EMT-like glioblastoma cells.
    British journal of cancer, 2017, Jun-27, Volume: 117, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Blotting, Western; Brain Neoplasms; Cell Line, Tumor; Cell Surviv

2017
The rs16906252:C>T SNP is not associated with increased overall survival or temozolomide response in a Han-Chinese glioma cohort.
    PloS one, 2017, Volume: 12, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Brain Neoplasms; China; Cohort Studies; Dacar

2017
The rs16906252:C>T SNP is not associated with increased overall survival or temozolomide response in a Han-Chinese glioma cohort.
    PloS one, 2017, Volume: 12, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Brain Neoplasms; China; Cohort Studies; Dacar

2017
The rs16906252:C>T SNP is not associated with increased overall survival or temozolomide response in a Han-Chinese glioma cohort.
    PloS one, 2017, Volume: 12, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Brain Neoplasms; China; Cohort Studies; Dacar

2017
Survival Outcomes of Elderly Patients With Glioblastoma Multiforme in Their 75th Year or Older Treated With Adjuvant Therapy.
    International journal of radiation oncology, biology, physics, 2017, 07-15, Volume: 98, Issue:4

    Topics: Age Factors; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2017
Survival Outcomes of Elderly Patients With Glioblastoma Multiforme in Their 75th Year or Older Treated With Adjuvant Therapy.
    International journal of radiation oncology, biology, physics, 2017, 07-15, Volume: 98, Issue:4

    Topics: Age Factors; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2017
Survival Outcomes of Elderly Patients With Glioblastoma Multiforme in Their 75th Year or Older Treated With Adjuvant Therapy.
    International journal of radiation oncology, biology, physics, 2017, 07-15, Volume: 98, Issue:4

    Topics: Age Factors; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2017
High Expression of Glypican-1 Predicts Dissemination and Poor Prognosis in Glioblastomas.
    World neurosurgery, 2017, Volume: 105

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain; Brain Neoplasms; Dacarbazine; Disease Progres

2017
High Expression of Glypican-1 Predicts Dissemination and Poor Prognosis in Glioblastomas.
    World neurosurgery, 2017, Volume: 105

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain; Brain Neoplasms; Dacarbazine; Disease Progres

2017
High Expression of Glypican-1 Predicts Dissemination and Poor Prognosis in Glioblastomas.
    World neurosurgery, 2017, Volume: 105

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain; Brain Neoplasms; Dacarbazine; Disease Progres

2017
Low Dose of Doxorubicin Potentiates the Effect of Temozolomide in Glioblastoma Cells.
    Molecular neurobiology, 2018, Volume: 55, Issue:5

    Topics: Brain Neoplasms; Cell Count; Cell Line, Tumor; Cell Proliferation; Cellular Senescence; Dose-Respons

2018
Low Dose of Doxorubicin Potentiates the Effect of Temozolomide in Glioblastoma Cells.
    Molecular neurobiology, 2018, Volume: 55, Issue:5

    Topics: Brain Neoplasms; Cell Count; Cell Line, Tumor; Cell Proliferation; Cellular Senescence; Dose-Respons

2018
Low Dose of Doxorubicin Potentiates the Effect of Temozolomide in Glioblastoma Cells.
    Molecular neurobiology, 2018, Volume: 55, Issue:5

    Topics: Brain Neoplasms; Cell Count; Cell Line, Tumor; Cell Proliferation; Cellular Senescence; Dose-Respons

2018
Effects of Connexin43 Overexpression on U251 Cell Growth, Migration, and Apoptosis.
    Medical science monitor : international medical journal of experimental and clinical research, 2017, Jun-15, Volume: 23

    Topics: Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cell Survival; Conn

2017
Effects of Connexin43 Overexpression on U251 Cell Growth, Migration, and Apoptosis.
    Medical science monitor : international medical journal of experimental and clinical research, 2017, Jun-15, Volume: 23

    Topics: Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cell Survival; Conn

2017
Effects of Connexin43 Overexpression on U251 Cell Growth, Migration, and Apoptosis.
    Medical science monitor : international medical journal of experimental and clinical research, 2017, Jun-15, Volume: 23

    Topics: Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cell Survival; Conn

2017
Connective tissue growth factor promotes temozolomide resistance in glioblastoma through TGF-β1-dependent activation of Smad/ERK signaling.
    Cell death & disease, 2017, 06-15, Volume: 8, Issue:6

    Topics: Animals; Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Connective

2017
Connective tissue growth factor promotes temozolomide resistance in glioblastoma through TGF-β1-dependent activation of Smad/ERK signaling.
    Cell death & disease, 2017, 06-15, Volume: 8, Issue:6

    Topics: Animals; Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Connective

2017
Connective tissue growth factor promotes temozolomide resistance in glioblastoma through TGF-β1-dependent activation of Smad/ERK signaling.
    Cell death & disease, 2017, 06-15, Volume: 8, Issue:6

    Topics: Animals; Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Connective

2017
New strategies for cancer management: how can temozolomide carrier modifications improve its delivery?
    Therapeutic delivery, 2017, Volume: 8, Issue:7

    Topics: Antineoplastic Agents, Alkylating; Blood-Brain Barrier; Brain Neoplasms; Dacarbazine; Drug Carriers;

2017
New strategies for cancer management: how can temozolomide carrier modifications improve its delivery?
    Therapeutic delivery, 2017, Volume: 8, Issue:7

    Topics: Antineoplastic Agents, Alkylating; Blood-Brain Barrier; Brain Neoplasms; Dacarbazine; Drug Carriers;

2017
New strategies for cancer management: how can temozolomide carrier modifications improve its delivery?
    Therapeutic delivery, 2017, Volume: 8, Issue:7

    Topics: Antineoplastic Agents, Alkylating; Blood-Brain Barrier; Brain Neoplasms; Dacarbazine; Drug Carriers;

2017
Frameless stereotactic radiotherapy alone and combined with temozolomide for presumed canine gliomas.
    Veterinary and comparative oncology, 2018, Volume: 16, Issue:1

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine;

2018
Frameless stereotactic radiotherapy alone and combined with temozolomide for presumed canine gliomas.
    Veterinary and comparative oncology, 2018, Volume: 16, Issue:1

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine;

2018
Frameless stereotactic radiotherapy alone and combined with temozolomide for presumed canine gliomas.
    Veterinary and comparative oncology, 2018, Volume: 16, Issue:1

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine;

2018
A Novel Theranostic Strategy for
    Molecular cancer therapeutics, 2017, Volume: 16, Issue:9

    Topics: Animals; Antineoplastic Agents; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cell Survival; Dacarba

2017
A Novel Theranostic Strategy for
    Molecular cancer therapeutics, 2017, Volume: 16, Issue:9

    Topics: Animals; Antineoplastic Agents; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cell Survival; Dacarba

2017
A Novel Theranostic Strategy for
    Molecular cancer therapeutics, 2017, Volume: 16, Issue:9

    Topics: Animals; Antineoplastic Agents; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cell Survival; Dacarba

2017
Liposomal temozolomide drug delivery using convection enhanced delivery.
    Journal of controlled release : official journal of the Controlled Release Society, 2017, 09-10, Volume: 261

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Convection; Dacarbazine; Drug Delivery

2017
Liposomal temozolomide drug delivery using convection enhanced delivery.
    Journal of controlled release : official journal of the Controlled Release Society, 2017, 09-10, Volume: 261

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Convection; Dacarbazine; Drug Delivery

2017
Liposomal temozolomide drug delivery using convection enhanced delivery.
    Journal of controlled release : official journal of the Controlled Release Society, 2017, 09-10, Volume: 261

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Convection; Dacarbazine; Drug Delivery

2017
Systemic Intravenous Adoptive Transfer of Autologous Lymphokine-activated αβ T-Cells Improves Temozolomide-induced Lymphopenia in Patients with Glioma.
    Anticancer research, 2017, Volume: 37, Issue:7

    Topics: Administration, Intravenous; Adolescent; Adult; Aged; Brain Neoplasms; Cell Line, Tumor; Child; Daca

2017
Systemic Intravenous Adoptive Transfer of Autologous Lymphokine-activated αβ T-Cells Improves Temozolomide-induced Lymphopenia in Patients with Glioma.
    Anticancer research, 2017, Volume: 37, Issue:7

    Topics: Administration, Intravenous; Adolescent; Adult; Aged; Brain Neoplasms; Cell Line, Tumor; Child; Daca

2017
Systemic Intravenous Adoptive Transfer of Autologous Lymphokine-activated αβ T-Cells Improves Temozolomide-induced Lymphopenia in Patients with Glioma.
    Anticancer research, 2017, Volume: 37, Issue:7

    Topics: Administration, Intravenous; Adolescent; Adult; Aged; Brain Neoplasms; Cell Line, Tumor; Child; Daca

2017
Long Non-Coding RNA MALAT1 Decreases the Sensitivity of Resistant Glioblastoma Cell Lines to Temozolomide.
    Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 2017, Volume: 42, Issue:3

    Topics: Antineoplastic Agents, Alkylating; Brain; Brain Neoplasms; Cell Line, Tumor; Dacarbazine; Drug Resis

2017
Long Non-Coding RNA MALAT1 Decreases the Sensitivity of Resistant Glioblastoma Cell Lines to Temozolomide.
    Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 2017, Volume: 42, Issue:3

    Topics: Antineoplastic Agents, Alkylating; Brain; Brain Neoplasms; Cell Line, Tumor; Dacarbazine; Drug Resis

2017
Long Non-Coding RNA MALAT1 Decreases the Sensitivity of Resistant Glioblastoma Cell Lines to Temozolomide.
    Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 2017, Volume: 42, Issue:3

    Topics: Antineoplastic Agents, Alkylating; Brain; Brain Neoplasms; Cell Line, Tumor; Dacarbazine; Drug Resis

2017
Long-term outcomes of concomitant chemoradiotherapy with temozolomide for newly diagnosed glioblastoma patients: A single-center analysis.
    Medicine, 2017, Volume: 96, Issue:27

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherap

2017
Long-term outcomes of concomitant chemoradiotherapy with temozolomide for newly diagnosed glioblastoma patients: A single-center analysis.
    Medicine, 2017, Volume: 96, Issue:27

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherap

2017
Long-term outcomes of concomitant chemoradiotherapy with temozolomide for newly diagnosed glioblastoma patients: A single-center analysis.
    Medicine, 2017, Volume: 96, Issue:27

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherap

2017
In vitro nuclear magnetic resonance spectroscopy metabolic biomarkers for the combination of temozolomide with PI3K inhibition in paediatric glioblastoma cells.
    PloS one, 2017, Volume: 12, Issue:7

    Topics: Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Brain Neoplasms; Cell Line, Tumor

2017
In vitro nuclear magnetic resonance spectroscopy metabolic biomarkers for the combination of temozolomide with PI3K inhibition in paediatric glioblastoma cells.
    PloS one, 2017, Volume: 12, Issue:7

    Topics: Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Brain Neoplasms; Cell Line, Tumor

2017
In vitro nuclear magnetic resonance spectroscopy metabolic biomarkers for the combination of temozolomide with PI3K inhibition in paediatric glioblastoma cells.
    PloS one, 2017, Volume: 12, Issue:7

    Topics: Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Brain Neoplasms; Cell Line, Tumor

2017
Genomic profiling of long non-coding RNA and mRNA expression associated with acquired temozolomide resistance in glioblastoma cells.
    International journal of oncology, 2017, Volume: 51, Issue:2

    Topics: Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Cell Survival; Dacarbazine; Drug Resistance,

2017
Genomic profiling of long non-coding RNA and mRNA expression associated with acquired temozolomide resistance in glioblastoma cells.
    International journal of oncology, 2017, Volume: 51, Issue:2

    Topics: Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Cell Survival; Dacarbazine; Drug Resistance,

2017
Genomic profiling of long non-coding RNA and mRNA expression associated with acquired temozolomide resistance in glioblastoma cells.
    International journal of oncology, 2017, Volume: 51, Issue:2

    Topics: Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Cell Survival; Dacarbazine; Drug Resistance,

2017
Risk of severe acute liver injury among patients with brain cancer treated with temozolomide: a nested case-control study using the healthcore integrated research database.
    Journal of neuro-oncology, 2017, Volume: 134, Issue:1

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Case

2017
Risk of severe acute liver injury among patients with brain cancer treated with temozolomide: a nested case-control study using the healthcore integrated research database.
    Journal of neuro-oncology, 2017, Volume: 134, Issue:1

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Case

2017
Risk of severe acute liver injury among patients with brain cancer treated with temozolomide: a nested case-control study using the healthcore integrated research database.
    Journal of neuro-oncology, 2017, Volume: 134, Issue:1

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Case

2017
A polymeric temozolomide nanocomposite against orthotopic glioblastoma xenograft: tumor-specific homing directed by nestin.
    Nanoscale, 2017, Aug-03, Volume: 9, Issue:30

    Topics: Animals; Blood-Brain Barrier; Brain Neoplasms; Cell Line, Tumor; Dacarbazine; Ferric Compounds; Glio

2017
A polymeric temozolomide nanocomposite against orthotopic glioblastoma xenograft: tumor-specific homing directed by nestin.
    Nanoscale, 2017, Aug-03, Volume: 9, Issue:30

    Topics: Animals; Blood-Brain Barrier; Brain Neoplasms; Cell Line, Tumor; Dacarbazine; Ferric Compounds; Glio

2017
A polymeric temozolomide nanocomposite against orthotopic glioblastoma xenograft: tumor-specific homing directed by nestin.
    Nanoscale, 2017, Aug-03, Volume: 9, Issue:30

    Topics: Animals; Blood-Brain Barrier; Brain Neoplasms; Cell Line, Tumor; Dacarbazine; Ferric Compounds; Glio

2017
Perfusion of surgical cavity wall enhancement in early post-treatment MR imaging may stratify the time-to-progression in glioblastoma.
    PloS one, 2017, Volume: 12, Issue:7

    Topics: Aged; Brain Neoplasms; Chemoradiotherapy; Combined Modality Therapy; Contrast Media; Dacarbazine; Di

2017
Perfusion of surgical cavity wall enhancement in early post-treatment MR imaging may stratify the time-to-progression in glioblastoma.
    PloS one, 2017, Volume: 12, Issue:7

    Topics: Aged; Brain Neoplasms; Chemoradiotherapy; Combined Modality Therapy; Contrast Media; Dacarbazine; Di

2017
Perfusion of surgical cavity wall enhancement in early post-treatment MR imaging may stratify the time-to-progression in glioblastoma.
    PloS one, 2017, Volume: 12, Issue:7

    Topics: Aged; Brain Neoplasms; Chemoradiotherapy; Combined Modality Therapy; Contrast Media; Dacarbazine; Di

2017
β-asarone inhibited cell growth and promoted autophagy via P53/Bcl-2/Bclin-1 and P53/AMPK/mTOR pathways in Human Glioma U251 cells.
    Journal of cellular physiology, 2018, Volume: 233, Issue:3

    Topics: Allylbenzene Derivatives; AMP-Activated Protein Kinases; Anisoles; Antineoplastic Agents; Antineopla

2018
β-asarone inhibited cell growth and promoted autophagy via P53/Bcl-2/Bclin-1 and P53/AMPK/mTOR pathways in Human Glioma U251 cells.
    Journal of cellular physiology, 2018, Volume: 233, Issue:3

    Topics: Allylbenzene Derivatives; AMP-Activated Protein Kinases; Anisoles; Antineoplastic Agents; Antineopla

2018
β-asarone inhibited cell growth and promoted autophagy via P53/Bcl-2/Bclin-1 and P53/AMPK/mTOR pathways in Human Glioma U251 cells.
    Journal of cellular physiology, 2018, Volume: 233, Issue:3

    Topics: Allylbenzene Derivatives; AMP-Activated Protein Kinases; Anisoles; Antineoplastic Agents; Antineopla

2018
FERMT3 contributes to glioblastoma cell proliferation and chemoresistance to temozolomide through integrin mediated Wnt signaling.
    Neuroscience letters, 2017, Sep-14, Volume: 657

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Dacarbazin

2017
FERMT3 contributes to glioblastoma cell proliferation and chemoresistance to temozolomide through integrin mediated Wnt signaling.
    Neuroscience letters, 2017, Sep-14, Volume: 657

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Dacarbazin

2017
FERMT3 contributes to glioblastoma cell proliferation and chemoresistance to temozolomide through integrin mediated Wnt signaling.
    Neuroscience letters, 2017, Sep-14, Volume: 657

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Dacarbazin

2017
Melanocortin Receptor-4 and Glioblastoma Cells: Effects of the Selective Antagonist ML00253764 Alone and in Combination with Temozolomide In Vitro and In Vivo.
    Molecular neurobiology, 2018, Volume: 55, Issue:6

    Topics: Animals; Apoptosis; Brain Neoplasms; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Drug Synergis

2018
Melanocortin Receptor-4 and Glioblastoma Cells: Effects of the Selective Antagonist ML00253764 Alone and in Combination with Temozolomide In Vitro and In Vivo.
    Molecular neurobiology, 2018, Volume: 55, Issue:6

    Topics: Animals; Apoptosis; Brain Neoplasms; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Drug Synergis

2018
Melanocortin Receptor-4 and Glioblastoma Cells: Effects of the Selective Antagonist ML00253764 Alone and in Combination with Temozolomide In Vitro and In Vivo.
    Molecular neurobiology, 2018, Volume: 55, Issue:6

    Topics: Animals; Apoptosis; Brain Neoplasms; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Drug Synergis

2018
Successful use of equine anti-thymocyte globulin (ATGAM) for fulminant myocarditis secondary to nivolumab therapy.
    British journal of cancer, 2017, Sep-26, Volume: 117, Issue:7

    Topics: Animals; Antibodies, Monoclonal; Antilymphocyte Serum; Antineoplastic Combined Chemotherapy Protocol

2017
Successful use of equine anti-thymocyte globulin (ATGAM) for fulminant myocarditis secondary to nivolumab therapy.
    British journal of cancer, 2017, Sep-26, Volume: 117, Issue:7

    Topics: Animals; Antibodies, Monoclonal; Antilymphocyte Serum; Antineoplastic Combined Chemotherapy Protocol

2017
Successful use of equine anti-thymocyte globulin (ATGAM) for fulminant myocarditis secondary to nivolumab therapy.
    British journal of cancer, 2017, Sep-26, Volume: 117, Issue:7

    Topics: Animals; Antibodies, Monoclonal; Antilymphocyte Serum; Antineoplastic Combined Chemotherapy Protocol

2017
Feasibility and safety of extended adjuvant temozolomide beyond six cycles for patients with glioblastoma.
    Hong Kong medical journal = Xianggang yi xue za zhi, 2017, Volume: 23, Issue:6

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Chemotherapy, Ad

2017
Feasibility and safety of extended adjuvant temozolomide beyond six cycles for patients with glioblastoma.
    Hong Kong medical journal = Xianggang yi xue za zhi, 2017, Volume: 23, Issue:6

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Chemotherapy, Ad

2017
Feasibility and safety of extended adjuvant temozolomide beyond six cycles for patients with glioblastoma.
    Hong Kong medical journal = Xianggang yi xue za zhi, 2017, Volume: 23, Issue:6

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Chemotherapy, Ad

2017
AAV-mediated direct in vivo CRISPR screen identifies functional suppressors in glioblastoma.
    Nature neuroscience, 2017, Volume: 20, Issue:10

    Topics: Animals; Brain Neoplasms; Cells, Cultured; CRISPR-Cas Systems; Dacarbazine; Dependovirus; DNA Mutati

2017
AAV-mediated direct in vivo CRISPR screen identifies functional suppressors in glioblastoma.
    Nature neuroscience, 2017, Volume: 20, Issue:10

    Topics: Animals; Brain Neoplasms; Cells, Cultured; CRISPR-Cas Systems; Dacarbazine; Dependovirus; DNA Mutati

2017
AAV-mediated direct in vivo CRISPR screen identifies functional suppressors in glioblastoma.
    Nature neuroscience, 2017, Volume: 20, Issue:10

    Topics: Animals; Brain Neoplasms; Cells, Cultured; CRISPR-Cas Systems; Dacarbazine; Dependovirus; DNA Mutati

2017
Blastomycosis and Histoplasmosis in a Patient with Glioblastoma Receiving Temozolomide.
    South Dakota medicine : the journal of the South Dakota State Medical Association, 2016, Volume: 69, Issue:10

    Topics: Antineoplastic Agents, Alkylating; Blastomycosis; Brain Neoplasms; Chemotherapy, Adjuvant; Dacarbazi

2016
Blastomycosis and Histoplasmosis in a Patient with Glioblastoma Receiving Temozolomide.
    South Dakota medicine : the journal of the South Dakota State Medical Association, 2016, Volume: 69, Issue:10

    Topics: Antineoplastic Agents, Alkylating; Blastomycosis; Brain Neoplasms; Chemotherapy, Adjuvant; Dacarbazi

2016
Blastomycosis and Histoplasmosis in a Patient with Glioblastoma Receiving Temozolomide.
    South Dakota medicine : the journal of the South Dakota State Medical Association, 2016, Volume: 69, Issue:10

    Topics: Antineoplastic Agents, Alkylating; Blastomycosis; Brain Neoplasms; Chemotherapy, Adjuvant; Dacarbazi

2016
Specificity protein 1-modulated superoxide dismutase 2 enhances temozolomide resistance in glioblastoma, which is independent of O
    Redox biology, 2017, Volume: 13

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Dacarbazine; DNA Modi

2017
Specificity protein 1-modulated superoxide dismutase 2 enhances temozolomide resistance in glioblastoma, which is independent of O
    Redox biology, 2017, Volume: 13

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Dacarbazine; DNA Modi

2017
Specificity protein 1-modulated superoxide dismutase 2 enhances temozolomide resistance in glioblastoma, which is independent of O
    Redox biology, 2017, Volume: 13

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Dacarbazine; DNA Modi

2017
Genetic driver mutations define the expression signature and microenvironmental composition of high-grade gliomas.
    Glia, 2017, Volume: 65, Issue:12

    Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Cerebral Vent

2017
Genetic driver mutations define the expression signature and microenvironmental composition of high-grade gliomas.
    Glia, 2017, Volume: 65, Issue:12

    Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Cerebral Vent

2017
Genetic driver mutations define the expression signature and microenvironmental composition of high-grade gliomas.
    Glia, 2017, Volume: 65, Issue:12

    Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Cerebral Vent

2017
Induction of Mitochondrial Dysfunction and Oxidative Damage by Antibiotic Drug Doxycycline Enhances the Responsiveness of Glioblastoma to Chemotherapy.
    Medical science monitor : international medical journal of experimental and clinical research, 2017, Aug-26, Volume: 23

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Brain Neoplasms; Cell Line, Tumo

2017
Induction of Mitochondrial Dysfunction and Oxidative Damage by Antibiotic Drug Doxycycline Enhances the Responsiveness of Glioblastoma to Chemotherapy.
    Medical science monitor : international medical journal of experimental and clinical research, 2017, Aug-26, Volume: 23

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Brain Neoplasms; Cell Line, Tumo

2017
Induction of Mitochondrial Dysfunction and Oxidative Damage by Antibiotic Drug Doxycycline Enhances the Responsiveness of Glioblastoma to Chemotherapy.
    Medical science monitor : international medical journal of experimental and clinical research, 2017, Aug-26, Volume: 23

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Brain Neoplasms; Cell Line, Tumo

2017
The use of TMZ embedded hydrogels for the treatment of orthotopic human glioma xenografts.
    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2017, Volume: 45

    Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Cell Line, Tumor; Dacarbazine; Disease Models, Anim

2017
The use of TMZ embedded hydrogels for the treatment of orthotopic human glioma xenografts.
    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2017, Volume: 45

    Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Cell Line, Tumor; Dacarbazine; Disease Models, Anim

2017
The use of TMZ embedded hydrogels for the treatment of orthotopic human glioma xenografts.
    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2017, Volume: 45

    Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Cell Line, Tumor; Dacarbazine; Disease Models, Anim

2017
Phase I/II Trial of Combination of Temozolomide Chemotherapy and Immunotherapy With Fusions of Dendritic and Glioma Cells in Patients With Glioblastoma.
    Neurosurgery, 2017, 07-01, Volume: 81, Issue:1

    Topics: Brain Neoplasms; Dacarbazine; Glioblastoma; Glioma; Humans; Immunotherapy; Temozolomide

2017
Phase I/II Trial of Combination of Temozolomide Chemotherapy and Immunotherapy With Fusions of Dendritic and Glioma Cells in Patients With Glioblastoma.
    Neurosurgery, 2017, 07-01, Volume: 81, Issue:1

    Topics: Brain Neoplasms; Dacarbazine; Glioblastoma; Glioma; Humans; Immunotherapy; Temozolomide

2017
Phase I/II Trial of Combination of Temozolomide Chemotherapy and Immunotherapy With Fusions of Dendritic and Glioma Cells in Patients With Glioblastoma.
    Neurosurgery, 2017, 07-01, Volume: 81, Issue:1

    Topics: Brain Neoplasms; Dacarbazine; Glioblastoma; Glioma; Humans; Immunotherapy; Temozolomide

2017
Zika virus has oncolytic activity against glioblastoma stem cells.
    The Journal of experimental medicine, 2017, Oct-02, Volume: 214, Issue:10

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; C

2017
Zika virus has oncolytic activity against glioblastoma stem cells.
    The Journal of experimental medicine, 2017, Oct-02, Volume: 214, Issue:10

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; C

2017
Zika virus has oncolytic activity against glioblastoma stem cells.
    The Journal of experimental medicine, 2017, Oct-02, Volume: 214, Issue:10

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; C

2017
Prognostic importance of temozolomide-induced neutropenia in glioblastoma, IDH-wildtype patients.
    Neurosurgical review, 2018, Volume: 41, Issue:2

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Female; Glioblastoma;

2018
Prognostic importance of temozolomide-induced neutropenia in glioblastoma, IDH-wildtype patients.
    Neurosurgical review, 2018, Volume: 41, Issue:2

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Female; Glioblastoma;

2018
Prognostic importance of temozolomide-induced neutropenia in glioblastoma, IDH-wildtype patients.
    Neurosurgical review, 2018, Volume: 41, Issue:2

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Female; Glioblastoma;

2018
Significance of perivascular tumour cells defined by CD109 expression in progression of glioma.
    The Journal of pathology, 2017, Volume: 243, Issue:4

    Topics: Animals; Antigens, CD; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Proliferation; Dacar

2017
Significance of perivascular tumour cells defined by CD109 expression in progression of glioma.
    The Journal of pathology, 2017, Volume: 243, Issue:4

    Topics: Animals; Antigens, CD; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Proliferation; Dacar

2017
Significance of perivascular tumour cells defined by CD109 expression in progression of glioma.
    The Journal of pathology, 2017, Volume: 243, Issue:4

    Topics: Animals; Antigens, CD; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Proliferation; Dacar

2017
MicroRNA-132 induces temozolomide resistance and promotes the formation of cancer stem cell phenotypes by targeting tumor suppressor candidate 3 in glioblastoma.
    International journal of molecular medicine, 2017, Volume: 40, Issue:5

    Topics: 3' Untranslated Regions; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Dacar

2017
MicroRNA-132 induces temozolomide resistance and promotes the formation of cancer stem cell phenotypes by targeting tumor suppressor candidate 3 in glioblastoma.
    International journal of molecular medicine, 2017, Volume: 40, Issue:5

    Topics: 3' Untranslated Regions; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Dacar

2017
MicroRNA-132 induces temozolomide resistance and promotes the formation of cancer stem cell phenotypes by targeting tumor suppressor candidate 3 in glioblastoma.
    International journal of molecular medicine, 2017, Volume: 40, Issue:5

    Topics: 3' Untranslated Regions; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Dacar

2017
Identification of WISP1 as a novel oncogene in glioblastoma.
    International journal of oncology, 2017, Volume: 51, Issue:4

    Topics: Brain Neoplasms; CCN Intercellular Signaling Proteins; Cell Line, Tumor; Cell Movement; Cell Prolife

2017
Identification of WISP1 as a novel oncogene in glioblastoma.
    International journal of oncology, 2017, Volume: 51, Issue:4

    Topics: Brain Neoplasms; CCN Intercellular Signaling Proteins; Cell Line, Tumor; Cell Movement; Cell Prolife

2017
Identification of WISP1 as a novel oncogene in glioblastoma.
    International journal of oncology, 2017, Volume: 51, Issue:4

    Topics: Brain Neoplasms; CCN Intercellular Signaling Proteins; Cell Line, Tumor; Cell Movement; Cell Prolife

2017
Controlled release of liposome-encapsulated temozolomide for brain tumour treatment by convection-enhanced delivery.
    Journal of drug targeting, 2018, Volume: 26, Issue:4

    Topics: 1,2-Dipalmitoylphosphatidylcholine; Animals; Antineoplastic Agents, Alkylating; Brain; Brain Neoplas

2018
Controlled release of liposome-encapsulated temozolomide for brain tumour treatment by convection-enhanced delivery.
    Journal of drug targeting, 2018, Volume: 26, Issue:4

    Topics: 1,2-Dipalmitoylphosphatidylcholine; Animals; Antineoplastic Agents, Alkylating; Brain; Brain Neoplas

2018
Controlled release of liposome-encapsulated temozolomide for brain tumour treatment by convection-enhanced delivery.
    Journal of drug targeting, 2018, Volume: 26, Issue:4

    Topics: 1,2-Dipalmitoylphosphatidylcholine; Animals; Antineoplastic Agents, Alkylating; Brain; Brain Neoplas

2018
Survival improvements with adjuvant therapy in patients with glioblastoma.
    ANZ journal of surgery, 2018, Volume: 88, Issue:3

    Topics: Adult; Aged; Analysis of Variance; Australia; Brain Neoplasms; Chemoradiotherapy, Adjuvant; Cohort S

2018
Survival improvements with adjuvant therapy in patients with glioblastoma.
    ANZ journal of surgery, 2018, Volume: 88, Issue:3

    Topics: Adult; Aged; Analysis of Variance; Australia; Brain Neoplasms; Chemoradiotherapy, Adjuvant; Cohort S

2018
Survival improvements with adjuvant therapy in patients with glioblastoma.
    ANZ journal of surgery, 2018, Volume: 88, Issue:3

    Topics: Adult; Aged; Analysis of Variance; Australia; Brain Neoplasms; Chemoradiotherapy, Adjuvant; Cohort S

2018
Temozolomide resistant human brain tumor stem cells are susceptible to recombinant vesicular stomatitis virus and double-deleted Vaccinia virus in vitro.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2017, Volume: 95

    Topics: Brain Neoplasms; Cell Death; Cell Differentiation; Cell Self Renewal; Dacarbazine; Drug Resistance,

2017
Temozolomide resistant human brain tumor stem cells are susceptible to recombinant vesicular stomatitis virus and double-deleted Vaccinia virus in vitro.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2017, Volume: 95

    Topics: Brain Neoplasms; Cell Death; Cell Differentiation; Cell Self Renewal; Dacarbazine; Drug Resistance,

2017
Temozolomide resistant human brain tumor stem cells are susceptible to recombinant vesicular stomatitis virus and double-deleted Vaccinia virus in vitro.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2017, Volume: 95

    Topics: Brain Neoplasms; Cell Death; Cell Differentiation; Cell Self Renewal; Dacarbazine; Drug Resistance,

2017
Impact of mesenchymal stem cells' secretome on glioblastoma pathophysiology.
    Journal of translational medicine, 2017, 10-02, Volume: 15, Issue:1

    Topics: Brain Neoplasms; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cell Survival; Culture Media,

2017
Impact of mesenchymal stem cells' secretome on glioblastoma pathophysiology.
    Journal of translational medicine, 2017, 10-02, Volume: 15, Issue:1

    Topics: Brain Neoplasms; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cell Survival; Culture Media,

2017
Impact of mesenchymal stem cells' secretome on glioblastoma pathophysiology.
    Journal of translational medicine, 2017, 10-02, Volume: 15, Issue:1

    Topics: Brain Neoplasms; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cell Survival; Culture Media,

2017
HB-EGF is associated with DNA damage and Mcl-1 turnover in human glioma cell lines treated by Temozolomide.
    Biochemical and biophysical research communications, 2017, 12-02, Volume: 493, Issue:4

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Dacarbazine; DNA Breaks, Doubl

2017
HB-EGF is associated with DNA damage and Mcl-1 turnover in human glioma cell lines treated by Temozolomide.
    Biochemical and biophysical research communications, 2017, 12-02, Volume: 493, Issue:4

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Dacarbazine; DNA Breaks, Doubl

2017
HB-EGF is associated with DNA damage and Mcl-1 turnover in human glioma cell lines treated by Temozolomide.
    Biochemical and biophysical research communications, 2017, 12-02, Volume: 493, Issue:4

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Dacarbazine; DNA Breaks, Doubl

2017
Divergent evolution of temozolomide resistance in glioblastoma stem cells is reflected in extracellular vesicles and coupled with radiosensitization.
    Neuro-oncology, 2018, 01-22, Volume: 20, Issue:2

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; D

2018
Divergent evolution of temozolomide resistance in glioblastoma stem cells is reflected in extracellular vesicles and coupled with radiosensitization.
    Neuro-oncology, 2018, 01-22, Volume: 20, Issue:2

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; D

2018
Divergent evolution of temozolomide resistance in glioblastoma stem cells is reflected in extracellular vesicles and coupled with radiosensitization.
    Neuro-oncology, 2018, 01-22, Volume: 20, Issue:2

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; D

2018
Concurrent radiotherapy with temozolomide vs. concurrent radiotherapy with a cisplatinum-based polychemotherapy regimen : Acute toxicity in pediatric high-grade glioma patients.
    Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 2018, Volume: 194, Issue:3

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Chemoradiotherapy; Chil

2018
Concurrent radiotherapy with temozolomide vs. concurrent radiotherapy with a cisplatinum-based polychemotherapy regimen : Acute toxicity in pediatric high-grade glioma patients.
    Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 2018, Volume: 194, Issue:3

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Chemoradiotherapy; Chil

2018
Concurrent radiotherapy with temozolomide vs. concurrent radiotherapy with a cisplatinum-based polychemotherapy regimen : Acute toxicity in pediatric high-grade glioma patients.
    Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 2018, Volume: 194, Issue:3

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Chemoradiotherapy; Chil

2018
Dynamic stroma reorganization drives blood vessel dysmorphia during glioma growth.
    EMBO molecular medicine, 2017, Volume: 9, Issue:12

    Topics: Animals; Antibodies, Monoclonal; Antineoplastic Agents, Alkylating; Blood Vessels; Brain Neoplasms;

2017
Dynamic stroma reorganization drives blood vessel dysmorphia during glioma growth.
    EMBO molecular medicine, 2017, Volume: 9, Issue:12

    Topics: Animals; Antibodies, Monoclonal; Antineoplastic Agents, Alkylating; Blood Vessels; Brain Neoplasms;

2017
Dynamic stroma reorganization drives blood vessel dysmorphia during glioma growth.
    EMBO molecular medicine, 2017, Volume: 9, Issue:12

    Topics: Animals; Antibodies, Monoclonal; Antineoplastic Agents, Alkylating; Blood Vessels; Brain Neoplasms;

2017
Hyperthermia with different temperatures inhibits proliferation and promotes apoptosis through the EGFR/STAT3 pathway in C6 rat glioma cells.
    Molecular medicine reports, 2017, Volume: 16, Issue:6

    Topics: Animals; Apoptosis; Brain Neoplasms; Carcinogenesis; Cell Line, Tumor; Cell Proliferation; Dacarbazi

2017
Hyperthermia with different temperatures inhibits proliferation and promotes apoptosis through the EGFR/STAT3 pathway in C6 rat glioma cells.
    Molecular medicine reports, 2017, Volume: 16, Issue:6

    Topics: Animals; Apoptosis; Brain Neoplasms; Carcinogenesis; Cell Line, Tumor; Cell Proliferation; Dacarbazi

2017
Hyperthermia with different temperatures inhibits proliferation and promotes apoptosis through the EGFR/STAT3 pathway in C6 rat glioma cells.
    Molecular medicine reports, 2017, Volume: 16, Issue:6

    Topics: Animals; Apoptosis; Brain Neoplasms; Carcinogenesis; Cell Line, Tumor; Cell Proliferation; Dacarbazi

2017
Sequential proton boost after standard chemoradiation for high-grade glioma.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2017, Volume: 125, Issue:2

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy, Adjuvant; Dacarb

2017
Sequential proton boost after standard chemoradiation for high-grade glioma.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2017, Volume: 125, Issue:2

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy, Adjuvant; Dacarb

2017
Sequential proton boost after standard chemoradiation for high-grade glioma.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2017, Volume: 125, Issue:2

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy, Adjuvant; Dacarb

2017
Epidermal Growth Factor Receptor Expression Predicts Time and Patterns of Recurrence in Patients with Glioblastoma After Radiotherapy and Temozolomide.
    World neurosurgery, 2018, Volume: 109

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Biomarkers, Tumor; Brain Neoplasm

2018
Epidermal Growth Factor Receptor Expression Predicts Time and Patterns of Recurrence in Patients with Glioblastoma After Radiotherapy and Temozolomide.
    World neurosurgery, 2018, Volume: 109

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Biomarkers, Tumor; Brain Neoplasm

2018
Epidermal Growth Factor Receptor Expression Predicts Time and Patterns of Recurrence in Patients with Glioblastoma After Radiotherapy and Temozolomide.
    World neurosurgery, 2018, Volume: 109

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Biomarkers, Tumor; Brain Neoplasm

2018
Immunotherapy with subcutaneous immunogenic autologous tumor lysate increases murine glioblastoma survival.
    Scientific reports, 2017, 10-24, Volume: 7, Issue:1

    Topics: Animals; Brain; Brain Neoplasms; Cell Line, Tumor; Combined Modality Therapy; Dendritic Cells; Femal

2017
Immunotherapy with subcutaneous immunogenic autologous tumor lysate increases murine glioblastoma survival.
    Scientific reports, 2017, 10-24, Volume: 7, Issue:1

    Topics: Animals; Brain; Brain Neoplasms; Cell Line, Tumor; Combined Modality Therapy; Dendritic Cells; Femal

2017
Immunotherapy with subcutaneous immunogenic autologous tumor lysate increases murine glioblastoma survival.
    Scientific reports, 2017, 10-24, Volume: 7, Issue:1

    Topics: Animals; Brain; Brain Neoplasms; Cell Line, Tumor; Combined Modality Therapy; Dendritic Cells; Femal

2017
Comparison between the Prebolus T1 Measurement and the Fixed T1 Value in Dynamic Contrast-Enhanced MR Imaging for the Differentiation of True Progression from Pseudoprogression in Glioblastoma Treated with Concurrent Radiation Therapy and Temozolomide Che
    AJNR. American journal of neuroradiology, 2017, Volume: 38, Issue:12

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Contrast Media;

2017
Comparison between the Prebolus T1 Measurement and the Fixed T1 Value in Dynamic Contrast-Enhanced MR Imaging for the Differentiation of True Progression from Pseudoprogression in Glioblastoma Treated with Concurrent Radiation Therapy and Temozolomide Che
    AJNR. American journal of neuroradiology, 2017, Volume: 38, Issue:12

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Contrast Media;

2017
Comparison between the Prebolus T1 Measurement and the Fixed T1 Value in Dynamic Contrast-Enhanced MR Imaging for the Differentiation of True Progression from Pseudoprogression in Glioblastoma Treated with Concurrent Radiation Therapy and Temozolomide Che
    AJNR. American journal of neuroradiology, 2017, Volume: 38, Issue:12

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Contrast Media;

2017
Recycling drug screen repurposes hydroxyurea as a sensitizer of glioblastomas to temozolomide targeting de novo DNA synthesis, irrespective of molecular subtype.
    Neuro-oncology, 2018, 04-09, Volume: 20, Issue:5

    Topics: Animals; Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cell Proliferation; DNA Repl

2018
Recycling drug screen repurposes hydroxyurea as a sensitizer of glioblastomas to temozolomide targeting de novo DNA synthesis, irrespective of molecular subtype.
    Neuro-oncology, 2018, 04-09, Volume: 20, Issue:5

    Topics: Animals; Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cell Proliferation; DNA Repl

2018
Recycling drug screen repurposes hydroxyurea as a sensitizer of glioblastomas to temozolomide targeting de novo DNA synthesis, irrespective of molecular subtype.
    Neuro-oncology, 2018, 04-09, Volume: 20, Issue:5

    Topics: Animals; Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cell Proliferation; DNA Repl

2018
Clinical and economic evaluation of modulated electrohyperthermia concurrent to dose-dense temozolomide 21/28 days regimen in the treatment of recurrent glioblastoma: a retrospective analysis of a two-centre German cohort trial with systematic comparison
    BMJ open, 2017, Nov-03, Volume: 7, Issue:11

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cost-Benefit Analysis; Dacarbazine;

2017
Clinical and economic evaluation of modulated electrohyperthermia concurrent to dose-dense temozolomide 21/28 days regimen in the treatment of recurrent glioblastoma: a retrospective analysis of a two-centre German cohort trial with systematic comparison
    BMJ open, 2017, Nov-03, Volume: 7, Issue:11

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cost-Benefit Analysis; Dacarbazine;

2017
Clinical and economic evaluation of modulated electrohyperthermia concurrent to dose-dense temozolomide 21/28 days regimen in the treatment of recurrent glioblastoma: a retrospective analysis of a two-centre German cohort trial with systematic comparison
    BMJ open, 2017, Nov-03, Volume: 7, Issue:11

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cost-Benefit Analysis; Dacarbazine;

2017
Increased signal intensity within glioblastoma resection cavities on fluid-attenuated inversion recovery imaging to detect early progressive disease in patients receiving radiotherapy with concomitant temozolomide therapy.
    Neuroradiology, 2018, Volume: 60, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2018
Increased signal intensity within glioblastoma resection cavities on fluid-attenuated inversion recovery imaging to detect early progressive disease in patients receiving radiotherapy with concomitant temozolomide therapy.
    Neuroradiology, 2018, Volume: 60, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2018
Increased signal intensity within glioblastoma resection cavities on fluid-attenuated inversion recovery imaging to detect early progressive disease in patients receiving radiotherapy with concomitant temozolomide therapy.
    Neuroradiology, 2018, Volume: 60, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2018
Comparative assessment of three methods to analyze MGMT methylation status in a series of 350 gliomas and gangliogliomas.
    Pathology, research and practice, 2017, Volume: 213, Issue:12

    Topics: Adult; Aged; Brain Neoplasms; Dacarbazine; DNA Methylation; DNA Modification Methylases; DNA Repair

2017
Comparative assessment of three methods to analyze MGMT methylation status in a series of 350 gliomas and gangliogliomas.
    Pathology, research and practice, 2017, Volume: 213, Issue:12

    Topics: Adult; Aged; Brain Neoplasms; Dacarbazine; DNA Methylation; DNA Modification Methylases; DNA Repair

2017
Comparative assessment of three methods to analyze MGMT methylation status in a series of 350 gliomas and gangliogliomas.
    Pathology, research and practice, 2017, Volume: 213, Issue:12

    Topics: Adult; Aged; Brain Neoplasms; Dacarbazine; DNA Methylation; DNA Modification Methylases; DNA Repair

2017
Glutathione reductase mediates drug resistance in glioblastoma cells by regulating redox homeostasis.
    Journal of neurochemistry, 2018, Volume: 144, Issue:1

    Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Buthionine Sulfoximine; Cell Line, Tumor; Cisplatin

2018
Glutathione reductase mediates drug resistance in glioblastoma cells by regulating redox homeostasis.
    Journal of neurochemistry, 2018, Volume: 144, Issue:1

    Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Buthionine Sulfoximine; Cell Line, Tumor; Cisplatin

2018
Glutathione reductase mediates drug resistance in glioblastoma cells by regulating redox homeostasis.
    Journal of neurochemistry, 2018, Volume: 144, Issue:1

    Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Buthionine Sulfoximine; Cell Line, Tumor; Cisplatin

2018
Tramadol attenuates the sensitivity of glioblastoma to temozolomide through the suppression of Cx43‑mediated gap junction intercellular communication.
    International journal of oncology, 2018, Volume: 52, Issue:1

    Topics: Analgesics, Opioid; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Communication; Cell Lin

2018
Tramadol attenuates the sensitivity of glioblastoma to temozolomide through the suppression of Cx43‑mediated gap junction intercellular communication.
    International journal of oncology, 2018, Volume: 52, Issue:1

    Topics: Analgesics, Opioid; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Communication; Cell Lin

2018
Tramadol attenuates the sensitivity of glioblastoma to temozolomide through the suppression of Cx43‑mediated gap junction intercellular communication.
    International journal of oncology, 2018, Volume: 52, Issue:1

    Topics: Analgesics, Opioid; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Communication; Cell Lin

2018
FTY720 inhibits the Nrf2/ARE pathway in human glioblastoma cell lines and sensitizes glioblastoma cells to temozolomide.
    Pharmacological reports : PR, 2017, Volume: 69, Issue:6

    Topics: Antineoplastic Agents, Alkylating; Antioxidant Response Elements; Apoptosis; Autophagy; Brain Neopla

2017
FTY720 inhibits the Nrf2/ARE pathway in human glioblastoma cell lines and sensitizes glioblastoma cells to temozolomide.
    Pharmacological reports : PR, 2017, Volume: 69, Issue:6

    Topics: Antineoplastic Agents, Alkylating; Antioxidant Response Elements; Apoptosis; Autophagy; Brain Neopla

2017
FTY720 inhibits the Nrf2/ARE pathway in human glioblastoma cell lines and sensitizes glioblastoma cells to temozolomide.
    Pharmacological reports : PR, 2017, Volume: 69, Issue:6

    Topics: Antineoplastic Agents, Alkylating; Antioxidant Response Elements; Apoptosis; Autophagy; Brain Neopla

2017
Upregulation of CASC2 sensitized glioma to temozolomide cytotoxicity through autophagy inhibition by sponging miR-193a-5p and regulating mTOR expression.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2018, Volume: 97

    Topics: Antineoplastic Agents, Alkylating; Apoptosis; Autophagy; Brain Neoplasms; Cell Line, Tumor; Cell Sur

2018
Upregulation of CASC2 sensitized glioma to temozolomide cytotoxicity through autophagy inhibition by sponging miR-193a-5p and regulating mTOR expression.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2018, Volume: 97

    Topics: Antineoplastic Agents, Alkylating; Apoptosis; Autophagy; Brain Neoplasms; Cell Line, Tumor; Cell Sur

2018
Upregulation of CASC2 sensitized glioma to temozolomide cytotoxicity through autophagy inhibition by sponging miR-193a-5p and regulating mTOR expression.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2018, Volume: 97

    Topics: Antineoplastic Agents, Alkylating; Apoptosis; Autophagy; Brain Neoplasms; Cell Line, Tumor; Cell Sur

2018
Long-term impact of temozolomide on 1p/19q-codeleted low-grade glioma growth kinetics.
    Journal of neuro-oncology, 2018, Volume: 136, Issue:3

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain; Brain Neoplasms; Chromosome Deletion; Chromos

2018
Long-term impact of temozolomide on 1p/19q-codeleted low-grade glioma growth kinetics.
    Journal of neuro-oncology, 2018, Volume: 136, Issue:3

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain; Brain Neoplasms; Chromosome Deletion; Chromos

2018
Long-term impact of temozolomide on 1p/19q-codeleted low-grade glioma growth kinetics.
    Journal of neuro-oncology, 2018, Volume: 136, Issue:3

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain; Brain Neoplasms; Chromosome Deletion; Chromos

2018
Enhancement of invadopodia activity in glioma cells by sublethal doses of irradiation and temozolomide.
    Journal of neurosurgery, 2018, Volume: 129, Issue:3

    Topics: Brain Neoplasms; Cell Line, Tumor; Combined Modality Therapy; Dose-Response Relationship, Drug; Glio

2018
Enhancement of invadopodia activity in glioma cells by sublethal doses of irradiation and temozolomide.
    Journal of neurosurgery, 2018, Volume: 129, Issue:3

    Topics: Brain Neoplasms; Cell Line, Tumor; Combined Modality Therapy; Dose-Response Relationship, Drug; Glio

2018
Enhancement of invadopodia activity in glioma cells by sublethal doses of irradiation and temozolomide.
    Journal of neurosurgery, 2018, Volume: 129, Issue:3

    Topics: Brain Neoplasms; Cell Line, Tumor; Combined Modality Therapy; Dose-Response Relationship, Drug; Glio

2018
Injectable Hydrogels for Localized Chemotherapy and Radiotherapy in Brain Tumors.
    Journal of pharmaceutical sciences, 2018, Volume: 107, Issue:3

    Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Cell Line, Tumor; Combined Modality Therapy; Dacarb

2018
Injectable Hydrogels for Localized Chemotherapy and Radiotherapy in Brain Tumors.
    Journal of pharmaceutical sciences, 2018, Volume: 107, Issue:3

    Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Cell Line, Tumor; Combined Modality Therapy; Dacarb

2018
Injectable Hydrogels for Localized Chemotherapy and Radiotherapy in Brain Tumors.
    Journal of pharmaceutical sciences, 2018, Volume: 107, Issue:3

    Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Cell Line, Tumor; Combined Modality Therapy; Dacarb

2018
NKG2D-Dependent Antitumor Effects of Chemotherapy and Radiotherapy against Glioblastoma.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2018, 02-15, Volume: 24, Issue:4

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Chemoradiotherapy; Ge

2018
NKG2D-Dependent Antitumor Effects of Chemotherapy and Radiotherapy against Glioblastoma.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2018, 02-15, Volume: 24, Issue:4

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Chemoradiotherapy; Ge

2018
NKG2D-Dependent Antitumor Effects of Chemotherapy and Radiotherapy against Glioblastoma.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2018, 02-15, Volume: 24, Issue:4

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Chemoradiotherapy; Ge

2018
Analysis of the cancer genome atlas (TCGA) database identifies an inverse relationship between interleukin-13 receptor α1 and α2 gene expression and poor prognosis and drug resistance in subjects with glioblastoma multiforme.
    Journal of neuro-oncology, 2018, Volume: 136, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Biomarkers, Pharmacological; Biom

2018
Analysis of the cancer genome atlas (TCGA) database identifies an inverse relationship between interleukin-13 receptor α1 and α2 gene expression and poor prognosis and drug resistance in subjects with glioblastoma multiforme.
    Journal of neuro-oncology, 2018, Volume: 136, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Biomarkers, Pharmacological; Biom

2018
Analysis of the cancer genome atlas (TCGA) database identifies an inverse relationship between interleukin-13 receptor α1 and α2 gene expression and poor prognosis and drug resistance in subjects with glioblastoma multiforme.
    Journal of neuro-oncology, 2018, Volume: 136, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Biomarkers, Pharmacological; Biom

2018
Modelling glioblastoma tumour-host cell interactions using adult brain organotypic slice co-culture.
    Disease models & mechanisms, 2018, 02-22, Volume: 11, Issue:2

    Topics: Aging; Animals; Antigens, CD; Biomarkers, Tumor; Brain; Brain Neoplasms; Cell Communication; Cell Pr

2018
Modelling glioblastoma tumour-host cell interactions using adult brain organotypic slice co-culture.
    Disease models & mechanisms, 2018, 02-22, Volume: 11, Issue:2

    Topics: Aging; Animals; Antigens, CD; Biomarkers, Tumor; Brain; Brain Neoplasms; Cell Communication; Cell Pr

2018
Modelling glioblastoma tumour-host cell interactions using adult brain organotypic slice co-culture.
    Disease models & mechanisms, 2018, 02-22, Volume: 11, Issue:2

    Topics: Aging; Animals; Antigens, CD; Biomarkers, Tumor; Brain; Brain Neoplasms; Cell Communication; Cell Pr

2018
Targeted nanocomplex carrying siRNA against MALAT1 sensitizes glioblastoma to temozolomide.
    Nucleic acids research, 2018, 02-16, Volume: 46, Issue:3

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Drug Resistance, Neop

2018
Targeted nanocomplex carrying siRNA against MALAT1 sensitizes glioblastoma to temozolomide.
    Nucleic acids research, 2018, 02-16, Volume: 46, Issue:3

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Drug Resistance, Neop

2018
Targeted nanocomplex carrying siRNA against MALAT1 sensitizes glioblastoma to temozolomide.
    Nucleic acids research, 2018, 02-16, Volume: 46, Issue:3

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Drug Resistance, Neop

2018
MRI to MGMT: predicting methylation status in glioblastoma patients using convolutional recurrent neural networks.
    Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing, 2018, Volume: 23

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Computational Biology; Dacarbazine; Databases, G

2018
MRI to MGMT: predicting methylation status in glioblastoma patients using convolutional recurrent neural networks.
    Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing, 2018, Volume: 23

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Computational Biology; Dacarbazine; Databases, G

2018
MRI to MGMT: predicting methylation status in glioblastoma patients using convolutional recurrent neural networks.
    Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing, 2018, Volume: 23

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Computational Biology; Dacarbazine; Databases, G

2018
Farewell to monomodality treatment in patients with WHO lower grade glioma?
    European journal of cancer (Oxford, England : 1990), 2018, Volume: 88

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Clinical Trials, Phase III as

2018
Farewell to monomodality treatment in patients with WHO lower grade glioma?
    European journal of cancer (Oxford, England : 1990), 2018, Volume: 88

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Clinical Trials, Phase III as

2018
Farewell to monomodality treatment in patients with WHO lower grade glioma?
    European journal of cancer (Oxford, England : 1990), 2018, Volume: 88

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Clinical Trials, Phase III as

2018
Anticancer activity of osmium(VI) nitrido complexes in patient-derived glioblastoma initiating cells and in vivo mouse models.
    Cancer letters, 2018, 03-01, Volume: 416

    Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Cell Line, Tumor; Cell Survival; Cisplatin; Coordin

2018
Anticancer activity of osmium(VI) nitrido complexes in patient-derived glioblastoma initiating cells and in vivo mouse models.
    Cancer letters, 2018, 03-01, Volume: 416

    Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Cell Line, Tumor; Cell Survival; Cisplatin; Coordin

2018
Anticancer activity of osmium(VI) nitrido complexes in patient-derived glioblastoma initiating cells and in vivo mouse models.
    Cancer letters, 2018, 03-01, Volume: 416

    Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Cell Line, Tumor; Cell Survival; Cisplatin; Coordin

2018
Calvarium mass as the first presentation of glioblastoma multiforme: A very rare manifestation of high-grade glioma.
    Neuro-Chirurgie, 2018, Volume: 64, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Frontal Lobe; Glioblastoma; Humans;

2018
Calvarium mass as the first presentation of glioblastoma multiforme: A very rare manifestation of high-grade glioma.
    Neuro-Chirurgie, 2018, Volume: 64, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Frontal Lobe; Glioblastoma; Humans;

2018
Calvarium mass as the first presentation of glioblastoma multiforme: A very rare manifestation of high-grade glioma.
    Neuro-Chirurgie, 2018, Volume: 64, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Frontal Lobe; Glioblastoma; Humans;

2018
The JAK2/STAT3 inhibitor pacritinib effectively inhibits patient-derived GBM brain tumor initiating cells in vitro and when used in combination with temozolomide increases survival in an orthotopic xenograft model.
    PloS one, 2017, Volume: 12, Issue:12

    Topics: Animals; Apoptosis; Blood-Brain Barrier; Brain Neoplasms; Bridged-Ring Compounds; Cell Proliferation

2017
The JAK2/STAT3 inhibitor pacritinib effectively inhibits patient-derived GBM brain tumor initiating cells in vitro and when used in combination with temozolomide increases survival in an orthotopic xenograft model.
    PloS one, 2017, Volume: 12, Issue:12

    Topics: Animals; Apoptosis; Blood-Brain Barrier; Brain Neoplasms; Bridged-Ring Compounds; Cell Proliferation

2017
The JAK2/STAT3 inhibitor pacritinib effectively inhibits patient-derived GBM brain tumor initiating cells in vitro and when used in combination with temozolomide increases survival in an orthotopic xenograft model.
    PloS one, 2017, Volume: 12, Issue:12

    Topics: Animals; Apoptosis; Blood-Brain Barrier; Brain Neoplasms; Bridged-Ring Compounds; Cell Proliferation

2017
Novel Targeting of Transcription and Metabolism in Glioblastoma.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2018, 03-01, Volume: 24, Issue:5

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Brain; Brain Neoplasms; Cell Lin

2018
Novel Targeting of Transcription and Metabolism in Glioblastoma.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2018, 03-01, Volume: 24, Issue:5

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Brain; Brain Neoplasms; Cell Lin

2018
Novel Targeting of Transcription and Metabolism in Glioblastoma.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2018, 03-01, Volume: 24, Issue:5

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Brain; Brain Neoplasms; Cell Lin

2018
Addition of carbonic anhydrase 9 inhibitor SLC-0111 to temozolomide treatment delays glioblastoma growth in vivo.
    JCI insight, 2017, 12-21, Volume: 2, Issue:24

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Cell Proliferation; DNA Da

2017
Addition of carbonic anhydrase 9 inhibitor SLC-0111 to temozolomide treatment delays glioblastoma growth in vivo.
    JCI insight, 2017, 12-21, Volume: 2, Issue:24

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Cell Proliferation; DNA Da

2017
Addition of carbonic anhydrase 9 inhibitor SLC-0111 to temozolomide treatment delays glioblastoma growth in vivo.
    JCI insight, 2017, 12-21, Volume: 2, Issue:24

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Cell Proliferation; DNA Da

2017
    The British journal of radiology, 2018, Volume: 91, Issue:1084

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Dihydroxyphenylalanine; Female; Gli

2018
    The British journal of radiology, 2018, Volume: 91, Issue:1084

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Dihydroxyphenylalanine; Female; Gli

2018
    The British journal of radiology, 2018, Volume: 91, Issue:1084

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Dihydroxyphenylalanine; Female; Gli

2018
Differential Characterization of Temozolomide-Resistant Human Glioma Cells.
    International journal of molecular sciences, 2018, Jan-02, Volume: 19, Issue:1

    Topics: Brain Neoplasms; Cell Adhesion; Cell Line, Tumor; Cell Movement; Connexin 43; Dacarbazine; DNA Modif

2018
Differential Characterization of Temozolomide-Resistant Human Glioma Cells.
    International journal of molecular sciences, 2018, Jan-02, Volume: 19, Issue:1

    Topics: Brain Neoplasms; Cell Adhesion; Cell Line, Tumor; Cell Movement; Connexin 43; Dacarbazine; DNA Modif

2018
Differential Characterization of Temozolomide-Resistant Human Glioma Cells.
    International journal of molecular sciences, 2018, Jan-02, Volume: 19, Issue:1

    Topics: Brain Neoplasms; Cell Adhesion; Cell Line, Tumor; Cell Movement; Connexin 43; Dacarbazine; DNA Modif

2018
Aldehyde dehydrogenase 1A3 (ALDH1A3) is regulated by autophagy in human glioblastoma cells.
    Cancer letters, 2018, 03-28, Volume: 417

    Topics: Aldehyde Oxidoreductases; Antineoplastic Agents, Alkylating; Autophagy; Brain Neoplasms; Cell Line,

2018
Aldehyde dehydrogenase 1A3 (ALDH1A3) is regulated by autophagy in human glioblastoma cells.
    Cancer letters, 2018, 03-28, Volume: 417

    Topics: Aldehyde Oxidoreductases; Antineoplastic Agents, Alkylating; Autophagy; Brain Neoplasms; Cell Line,

2018
Aldehyde dehydrogenase 1A3 (ALDH1A3) is regulated by autophagy in human glioblastoma cells.
    Cancer letters, 2018, 03-28, Volume: 417

    Topics: Aldehyde Oxidoreductases; Antineoplastic Agents, Alkylating; Autophagy; Brain Neoplasms; Cell Line,

2018
High-Dose Metformin Plus Temozolomide Shows Increased Anti-tumor Effects in Glioblastoma In Vitro and In Vivo Compared with Monotherapy.
    Cancer research and treatment, 2018, Volume: 50, Issue:4

    Topics: AMP-Activated Protein Kinases; Animals; Antineoplastic Combined Chemotherapy Protocols; Brain Neopla

2018
High-Dose Metformin Plus Temozolomide Shows Increased Anti-tumor Effects in Glioblastoma In Vitro and In Vivo Compared with Monotherapy.
    Cancer research and treatment, 2018, Volume: 50, Issue:4

    Topics: AMP-Activated Protein Kinases; Animals; Antineoplastic Combined Chemotherapy Protocols; Brain Neopla

2018
High-Dose Metformin Plus Temozolomide Shows Increased Anti-tumor Effects in Glioblastoma In Vitro and In Vivo Compared with Monotherapy.
    Cancer research and treatment, 2018, Volume: 50, Issue:4

    Topics: AMP-Activated Protein Kinases; Animals; Antineoplastic Combined Chemotherapy Protocols; Brain Neopla

2018
Temozolomide-induced increase of tumorigenicity can be diminished by targeting of mitochondria in in vitro models of patient individual glioblastoma.
    PloS one, 2018, Volume: 13, Issue:1

    Topics: Anti-Bacterial Agents; Antineoplastic Agents, Alkylating; Biomarkers, Tumor; Brain Neoplasms; Cell D

2018
Temozolomide-induced increase of tumorigenicity can be diminished by targeting of mitochondria in in vitro models of patient individual glioblastoma.
    PloS one, 2018, Volume: 13, Issue:1

    Topics: Anti-Bacterial Agents; Antineoplastic Agents, Alkylating; Biomarkers, Tumor; Brain Neoplasms; Cell D

2018
Temozolomide-induced increase of tumorigenicity can be diminished by targeting of mitochondria in in vitro models of patient individual glioblastoma.
    PloS one, 2018, Volume: 13, Issue:1

    Topics: Anti-Bacterial Agents; Antineoplastic Agents, Alkylating; Biomarkers, Tumor; Brain Neoplasms; Cell D

2018
NKG2D ligands in glioma stem-like cells: expression in situ and in vitro.
    Histochemistry and cell biology, 2018, Volume: 149, Issue:3

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Differentiation; Dacarbazine;

2018
NKG2D ligands in glioma stem-like cells: expression in situ and in vitro.
    Histochemistry and cell biology, 2018, Volume: 149, Issue:3

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Differentiation; Dacarbazine;

2018
NKG2D ligands in glioma stem-like cells: expression in situ and in vitro.
    Histochemistry and cell biology, 2018, Volume: 149, Issue:3

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Differentiation; Dacarbazine;

2018
Biomimetic brain tumor niche regulates glioblastoma cells towards a cancer stem cell phenotype.
    Journal of neuro-oncology, 2018, Volume: 137, Issue:3

    Topics: AC133 Antigen; Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cell

2018
Biomimetic brain tumor niche regulates glioblastoma cells towards a cancer stem cell phenotype.
    Journal of neuro-oncology, 2018, Volume: 137, Issue:3

    Topics: AC133 Antigen; Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cell

2018
Biomimetic brain tumor niche regulates glioblastoma cells towards a cancer stem cell phenotype.
    Journal of neuro-oncology, 2018, Volume: 137, Issue:3

    Topics: AC133 Antigen; Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cell

2018
Up-regulation of MSH6 is associated with temozolomide resistance in human glioblastoma.
    Biochemical and biophysical research communications, 2018, 02-19, Volume: 496, Issue:4

    Topics: Adult; Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Dacarbazine; DNA-Binding Prote

2018
Up-regulation of MSH6 is associated with temozolomide resistance in human glioblastoma.
    Biochemical and biophysical research communications, 2018, 02-19, Volume: 496, Issue:4

    Topics: Adult; Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Dacarbazine; DNA-Binding Prote

2018
Up-regulation of MSH6 is associated with temozolomide resistance in human glioblastoma.
    Biochemical and biophysical research communications, 2018, 02-19, Volume: 496, Issue:4

    Topics: Adult; Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Dacarbazine; DNA-Binding Prote

2018
Photon vs. proton radiochemotherapy: Effects on brain tissue volume and perfusion.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2018, Volume: 128, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain; Brain Neoplasms; Cerebrova

2018
Photon vs. proton radiochemotherapy: Effects on brain tissue volume and perfusion.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2018, Volume: 128, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain; Brain Neoplasms; Cerebrova

2018
Photon vs. proton radiochemotherapy: Effects on brain tissue volume and perfusion.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2018, Volume: 128, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain; Brain Neoplasms; Cerebrova

2018
Loss of ATRX suppresses ATM dependent DNA damage repair by modulating H3K9me3 to enhance temozolomide sensitivity in glioma.
    Cancer letters, 2018, 04-10, Volume: 419

    Topics: Animals; Antineoplastic Agents, Alkylating; Ataxia Telangiectasia Mutated Proteins; Brain Neoplasms;

2018
Loss of ATRX suppresses ATM dependent DNA damage repair by modulating H3K9me3 to enhance temozolomide sensitivity in glioma.
    Cancer letters, 2018, 04-10, Volume: 419

    Topics: Animals; Antineoplastic Agents, Alkylating; Ataxia Telangiectasia Mutated Proteins; Brain Neoplasms;

2018
Loss of ATRX suppresses ATM dependent DNA damage repair by modulating H3K9me3 to enhance temozolomide sensitivity in glioma.
    Cancer letters, 2018, 04-10, Volume: 419

    Topics: Animals; Antineoplastic Agents, Alkylating; Ataxia Telangiectasia Mutated Proteins; Brain Neoplasms;

2018
Where does O
    Cancer, 2018, 04-01, Volume: 124, Issue:7

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; DNA Methylation; Glioblastoma; Humans; O(6)-Meth

2018
Where does O
    Cancer, 2018, 04-01, Volume: 124, Issue:7

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; DNA Methylation; Glioblastoma; Humans; O(6)-Meth

2018
Where does O
    Cancer, 2018, 04-01, Volume: 124, Issue:7

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; DNA Methylation; Glioblastoma; Humans; O(6)-Meth

2018
Standard dose and dose-escalated radiation therapy are associated with favorable survival in select elderly patients with newly diagnosed glioblastoma.
    Journal of neuro-oncology, 2018, Volume: 138, Issue:1

    Topics: Age Factors; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dose-Respo

2018
Standard dose and dose-escalated radiation therapy are associated with favorable survival in select elderly patients with newly diagnosed glioblastoma.
    Journal of neuro-oncology, 2018, Volume: 138, Issue:1

    Topics: Age Factors; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dose-Respo

2018
Standard dose and dose-escalated radiation therapy are associated with favorable survival in select elderly patients with newly diagnosed glioblastoma.
    Journal of neuro-oncology, 2018, Volume: 138, Issue:1

    Topics: Age Factors; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dose-Respo

2018
Chemotherapy of Diffuse Astrocytoma (WHO grade II) in Adults.
    Progress in neurological surgery, 2018, Volume: 31

    Topics: Adult; Astrocytoma; Brain Neoplasms; Chemotherapy, Adjuvant; Dacarbazine; Glioma; Humans; Procarbazi

2018
Chemotherapy of Diffuse Astrocytoma (WHO grade II) in Adults.
    Progress in neurological surgery, 2018, Volume: 31

    Topics: Adult; Astrocytoma; Brain Neoplasms; Chemotherapy, Adjuvant; Dacarbazine; Glioma; Humans; Procarbazi

2018
Chemotherapy of Diffuse Astrocytoma (WHO grade II) in Adults.
    Progress in neurological surgery, 2018, Volume: 31

    Topics: Adult; Astrocytoma; Brain Neoplasms; Chemotherapy, Adjuvant; Dacarbazine; Glioma; Humans; Procarbazi

2018
Chemotherapy of Oligodendrogliomas.
    Progress in neurological surgery, 2018, Volume: 31

    Topics: Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Chemotherapy, Adjuvant; Dacarbazine

2018
Chemotherapy of Oligodendrogliomas.
    Progress in neurological surgery, 2018, Volume: 31

    Topics: Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Chemotherapy, Adjuvant; Dacarbazine

2018
Chemotherapy of Oligodendrogliomas.
    Progress in neurological surgery, 2018, Volume: 31

    Topics: Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Chemotherapy, Adjuvant; Dacarbazine

2018
Long non-coding RNA TUSC7 inhibits temozolomide resistance by targeting miR-10a in glioblastoma.
    Cancer chemotherapy and pharmacology, 2018, Volume: 81, Issue:4

    Topics: Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cell Cycle; Cell Proliferation; Drug

2018
Long non-coding RNA TUSC7 inhibits temozolomide resistance by targeting miR-10a in glioblastoma.
    Cancer chemotherapy and pharmacology, 2018, Volume: 81, Issue:4

    Topics: Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cell Cycle; Cell Proliferation; Drug

2018
Long non-coding RNA TUSC7 inhibits temozolomide resistance by targeting miR-10a in glioblastoma.
    Cancer chemotherapy and pharmacology, 2018, Volume: 81, Issue:4

    Topics: Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cell Cycle; Cell Proliferation; Drug

2018
Quantitative Magnetization Transfer in Monitoring Glioblastoma (GBM) Response to Therapy.
    Scientific reports, 2018, 02-06, Volume: 8, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Brain; Brain Neoplasms; Disease Progression; Female; Gamma Rays;

2018
Quantitative Magnetization Transfer in Monitoring Glioblastoma (GBM) Response to Therapy.
    Scientific reports, 2018, 02-06, Volume: 8, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Brain; Brain Neoplasms; Disease Progression; Female; Gamma Rays;

2018
Quantitative Magnetization Transfer in Monitoring Glioblastoma (GBM) Response to Therapy.
    Scientific reports, 2018, 02-06, Volume: 8, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Brain; Brain Neoplasms; Disease Progression; Female; Gamma Rays;

2018
Interference with PSMB4 Expression Exerts an Anti-Tumor Effect by Decreasing the Invasion and Proliferation of Human Glioblastoma Cells.
    Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 2018, Volume: 45, Issue:2

    Topics: Animals; Apoptosis; Brain Neoplasms; Cathepsin B; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Mov

2018
Interference with PSMB4 Expression Exerts an Anti-Tumor Effect by Decreasing the Invasion and Proliferation of Human Glioblastoma Cells.
    Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 2018, Volume: 45, Issue:2

    Topics: Animals; Apoptosis; Brain Neoplasms; Cathepsin B; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Mov

2018
Interference with PSMB4 Expression Exerts an Anti-Tumor Effect by Decreasing the Invasion and Proliferation of Human Glioblastoma Cells.
    Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 2018, Volume: 45, Issue:2

    Topics: Animals; Apoptosis; Brain Neoplasms; Cathepsin B; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Mov

2018
Fasudil increases temozolomide sensitivity and suppresses temozolomide-resistant glioma growth via inhibiting ROCK2/ABCG2.
    Cell death & disease, 2018, 02-07, Volume: 9, Issue:2

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Antineoplastic Combined Chemotherapy Protoco

2018
Fasudil increases temozolomide sensitivity and suppresses temozolomide-resistant glioma growth via inhibiting ROCK2/ABCG2.
    Cell death & disease, 2018, 02-07, Volume: 9, Issue:2

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Antineoplastic Combined Chemotherapy Protoco

2018
Fasudil increases temozolomide sensitivity and suppresses temozolomide-resistant glioma growth via inhibiting ROCK2/ABCG2.
    Cell death & disease, 2018, 02-07, Volume: 9, Issue:2

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Antineoplastic Combined Chemotherapy Protoco

2018
A primitive neuroectodermal tumor in an adult: Case report of a unique location and MRI characteristics.
    Medicine, 2018, Volume: 97, Issue:7

    Topics: Adult; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cerebral Ventricles; Chemotherapy, Adjuva

2018
A primitive neuroectodermal tumor in an adult: Case report of a unique location and MRI characteristics.
    Medicine, 2018, Volume: 97, Issue:7

    Topics: Adult; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cerebral Ventricles; Chemotherapy, Adjuva

2018
A primitive neuroectodermal tumor in an adult: Case report of a unique location and MRI characteristics.
    Medicine, 2018, Volume: 97, Issue:7

    Topics: Adult; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cerebral Ventricles; Chemotherapy, Adjuva

2018
Temozolomide affects Extracellular Vesicles Released by Glioblastoma Cells.
    Biochimie, 2018, Volume: 155

    Topics: Brain Neoplasms; Cell Adhesion; Cell Line, Tumor; Extracellular Vesicles; Female; Glioblastoma; Huma

2018
Temozolomide affects Extracellular Vesicles Released by Glioblastoma Cells.
    Biochimie, 2018, Volume: 155

    Topics: Brain Neoplasms; Cell Adhesion; Cell Line, Tumor; Extracellular Vesicles; Female; Glioblastoma; Huma

2018
Temozolomide affects Extracellular Vesicles Released by Glioblastoma Cells.
    Biochimie, 2018, Volume: 155

    Topics: Brain Neoplasms; Cell Adhesion; Cell Line, Tumor; Extracellular Vesicles; Female; Glioblastoma; Huma

2018
MiR-634 sensitizes glioma cells to temozolomide by targeting CYR61 through Raf-ERK signaling pathway.
    Cancer medicine, 2018, Volume: 7, Issue:3

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Cysteine-Rich Pro

2018
MiR-634 sensitizes glioma cells to temozolomide by targeting CYR61 through Raf-ERK signaling pathway.
    Cancer medicine, 2018, Volume: 7, Issue:3

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Cysteine-Rich Pro

2018
MiR-634 sensitizes glioma cells to temozolomide by targeting CYR61 through Raf-ERK signaling pathway.
    Cancer medicine, 2018, Volume: 7, Issue:3

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Cysteine-Rich Pro

2018
Advantages and Disadvantages of Combined Chemotherapy with Carmustine Wafer and Bevacizumab in Patients with Newly Diagnosed Glioblastoma: A Single-Institutional Experience.
    World neurosurgery, 2018, Volume: 113

    Topics: Adult; Aged; Angiogenesis Inhibitors; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; B

2018
Advantages and Disadvantages of Combined Chemotherapy with Carmustine Wafer and Bevacizumab in Patients with Newly Diagnosed Glioblastoma: A Single-Institutional Experience.
    World neurosurgery, 2018, Volume: 113

    Topics: Adult; Aged; Angiogenesis Inhibitors; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; B

2018
Advantages and Disadvantages of Combined Chemotherapy with Carmustine Wafer and Bevacizumab in Patients with Newly Diagnosed Glioblastoma: A Single-Institutional Experience.
    World neurosurgery, 2018, Volume: 113

    Topics: Adult; Aged; Angiogenesis Inhibitors; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; B

2018
Transcriptional control of O
    Journal of neurochemistry, 2018, Volume: 144, Issue:6

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; Gen

2018
Transcriptional control of O
    Journal of neurochemistry, 2018, Volume: 144, Issue:6

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; Gen

2018
Transcriptional control of O
    Journal of neurochemistry, 2018, Volume: 144, Issue:6

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; Gen

2018
Risk Factors for Malignant Transformation of Low-Grade Glioma.
    International journal of radiation oncology, biology, physics, 2018, 03-15, Volume: 100, Issue:4

    Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Analysis of Variance; Antineoplastic Agents

2018
Risk Factors for Malignant Transformation of Low-Grade Glioma.
    International journal of radiation oncology, biology, physics, 2018, 03-15, Volume: 100, Issue:4

    Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Analysis of Variance; Antineoplastic Agents

2018
Risk Factors for Malignant Transformation of Low-Grade Glioma.
    International journal of radiation oncology, biology, physics, 2018, 03-15, Volume: 100, Issue:4

    Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Analysis of Variance; Antineoplastic Agents

2018
A HIF-independent, CD133-mediated mechanism of cisplatin resistance in glioblastoma cells.
    Cellular oncology (Dordrecht), 2018, Volume: 41, Issue:3

    Topics: AC133 Antigen; Basic Helix-Loop-Helix Transcription Factors; Brain Neoplasms; Cell Line, Tumor; Cisp

2018
A HIF-independent, CD133-mediated mechanism of cisplatin resistance in glioblastoma cells.
    Cellular oncology (Dordrecht), 2018, Volume: 41, Issue:3

    Topics: AC133 Antigen; Basic Helix-Loop-Helix Transcription Factors; Brain Neoplasms; Cell Line, Tumor; Cisp

2018
A HIF-independent, CD133-mediated mechanism of cisplatin resistance in glioblastoma cells.
    Cellular oncology (Dordrecht), 2018, Volume: 41, Issue:3

    Topics: AC133 Antigen; Basic Helix-Loop-Helix Transcription Factors; Brain Neoplasms; Cell Line, Tumor; Cisp

2018
ATP binding cassette (ABC) transporters: expression and clinical value in glioblastoma.
    Journal of neuro-oncology, 2018, Volume: 138, Issue:3

    Topics: Antineoplastic Agents, Alkylating; ATP-Binding Cassette Transporters; Biomarkers, Tumor; Brain Neopl

2018
ATP binding cassette (ABC) transporters: expression and clinical value in glioblastoma.
    Journal of neuro-oncology, 2018, Volume: 138, Issue:3

    Topics: Antineoplastic Agents, Alkylating; ATP-Binding Cassette Transporters; Biomarkers, Tumor; Brain Neopl

2018
ATP binding cassette (ABC) transporters: expression and clinical value in glioblastoma.
    Journal of neuro-oncology, 2018, Volume: 138, Issue:3

    Topics: Antineoplastic Agents, Alkylating; ATP-Binding Cassette Transporters; Biomarkers, Tumor; Brain Neopl

2018
Upregulation of miR-125b, miR-181d, and miR-221 Predicts Poor Prognosis in MGMT Promoter-Unmethylated Glioblastoma Patients.
    American journal of clinical pathology, 2018, Mar-29, Volume: 149, Issue:5

    Topics: Brain Neoplasms; DNA Methylation; DNA Modification Methylases; DNA Repair Enzymes; Gene Expression R

2018
Upregulation of miR-125b, miR-181d, and miR-221 Predicts Poor Prognosis in MGMT Promoter-Unmethylated Glioblastoma Patients.
    American journal of clinical pathology, 2018, Mar-29, Volume: 149, Issue:5

    Topics: Brain Neoplasms; DNA Methylation; DNA Modification Methylases; DNA Repair Enzymes; Gene Expression R

2018
Upregulation of miR-125b, miR-181d, and miR-221 Predicts Poor Prognosis in MGMT Promoter-Unmethylated Glioblastoma Patients.
    American journal of clinical pathology, 2018, Mar-29, Volume: 149, Issue:5

    Topics: Brain Neoplasms; DNA Methylation; DNA Modification Methylases; DNA Repair Enzymes; Gene Expression R

2018
Tumor Volume Changes During and After Temozolomide Treatment for Newly Diagnosed Higher-Grade Glioma (III and IV).
    World neurosurgery, 2018, Volume: 114

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neoplasms; Com

2018
Tumor Volume Changes During and After Temozolomide Treatment for Newly Diagnosed Higher-Grade Glioma (III and IV).
    World neurosurgery, 2018, Volume: 114

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neoplasms; Com

2018
Tumor Volume Changes During and After Temozolomide Treatment for Newly Diagnosed Higher-Grade Glioma (III and IV).
    World neurosurgery, 2018, Volume: 114

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neoplasms; Com

2018
Characterizing the molecular mechanisms of acquired temozolomide resistance in the U251 glioblastoma cell line by protein microarray.
    Oncology reports, 2018, Volume: 39, Issue:5

    Topics: Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Dacarbazine; Drug Resistance, Neop

2018
Characterizing the molecular mechanisms of acquired temozolomide resistance in the U251 glioblastoma cell line by protein microarray.
    Oncology reports, 2018, Volume: 39, Issue:5

    Topics: Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Dacarbazine; Drug Resistance, Neop

2018
Characterizing the molecular mechanisms of acquired temozolomide resistance in the U251 glioblastoma cell line by protein microarray.
    Oncology reports, 2018, Volume: 39, Issue:5

    Topics: Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Dacarbazine; Drug Resistance, Neop

2018
XRCC3 contributes to temozolomide resistance of glioblastoma cells by promoting DNA double-strand break repair.
    Cancer letters, 2018, 06-28, Volume: 424

    Topics: Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; DNA Breaks, Double-Stranded; DNA Repair; DNA-

2018
XRCC3 contributes to temozolomide resistance of glioblastoma cells by promoting DNA double-strand break repair.
    Cancer letters, 2018, 06-28, Volume: 424

    Topics: Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; DNA Breaks, Double-Stranded; DNA Repair; DNA-

2018
XRCC3 contributes to temozolomide resistance of glioblastoma cells by promoting DNA double-strand break repair.
    Cancer letters, 2018, 06-28, Volume: 424

    Topics: Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; DNA Breaks, Double-Stranded; DNA Repair; DNA-

2018
DMC is not better than TMZ on intracranial anti-glioma effects.
    Journal of cellular biochemistry, 2018, Volume: 119, Issue:7

    Topics: Animals; Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cell Proliferation; Curcumin

2018
DMC is not better than TMZ on intracranial anti-glioma effects.
    Journal of cellular biochemistry, 2018, Volume: 119, Issue:7

    Topics: Animals; Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cell Proliferation; Curcumin

2018
DMC is not better than TMZ on intracranial anti-glioma effects.
    Journal of cellular biochemistry, 2018, Volume: 119, Issue:7

    Topics: Animals; Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cell Proliferation; Curcumin

2018
Improvement of health related quality of life in patients with recurrent glioma treated with bevacizumab plus daily temozolomide as the salvage therapy.
    Clinical neurology and neurosurgery, 2018, Volume: 169

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Immunological; An

2018
Improvement of health related quality of life in patients with recurrent glioma treated with bevacizumab plus daily temozolomide as the salvage therapy.
    Clinical neurology and neurosurgery, 2018, Volume: 169

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Immunological; An

2018
Improvement of health related quality of life in patients with recurrent glioma treated with bevacizumab plus daily temozolomide as the salvage therapy.
    Clinical neurology and neurosurgery, 2018, Volume: 169

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Immunological; An

2018
A Comparative Analysis of the Usefulness of Survival Prediction Models for Patients with Glioblastoma in the Temozolomide Era: The Importance of Methylguanine Methyltransferase Promoter Methylation, Extent of Resection, and Subventricular Zone Location.
    World neurosurgery, 2018, Volume: 115

    Topics: Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Comb

2018
A Comparative Analysis of the Usefulness of Survival Prediction Models for Patients with Glioblastoma in the Temozolomide Era: The Importance of Methylguanine Methyltransferase Promoter Methylation, Extent of Resection, and Subventricular Zone Location.
    World neurosurgery, 2018, Volume: 115

    Topics: Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Comb

2018
A Comparative Analysis of the Usefulness of Survival Prediction Models for Patients with Glioblastoma in the Temozolomide Era: The Importance of Methylguanine Methyltransferase Promoter Methylation, Extent of Resection, and Subventricular Zone Location.
    World neurosurgery, 2018, Volume: 115

    Topics: Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Comb

2018
Identification of Key Candidate Proteins and Pathways Associated with Temozolomide Resistance in Glioblastoma Based on Subcellular Proteomics and Bioinformatical Analysis.
    BioMed research international, 2018, Volume: 2018

    Topics: Biomarkers, Tumor; Brain Neoplasms; Cell Line, Tumor; Computational Biology; Dacarbazine; Down-Regul

2018
Identification of Key Candidate Proteins and Pathways Associated with Temozolomide Resistance in Glioblastoma Based on Subcellular Proteomics and Bioinformatical Analysis.
    BioMed research international, 2018, Volume: 2018

    Topics: Biomarkers, Tumor; Brain Neoplasms; Cell Line, Tumor; Computational Biology; Dacarbazine; Down-Regul

2018
Identification of Key Candidate Proteins and Pathways Associated with Temozolomide Resistance in Glioblastoma Based on Subcellular Proteomics and Bioinformatical Analysis.
    BioMed research international, 2018, Volume: 2018

    Topics: Biomarkers, Tumor; Brain Neoplasms; Cell Line, Tumor; Computational Biology; Dacarbazine; Down-Regul

2018
Prognostic value of the Glasgow Prognostic Score for glioblastoma multiforme patients treated with radiotherapy and temozolomide.
    Journal of neuro-oncology, 2018, Volume: 139, Issue:2

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Female; Glioblas

2018
Prognostic value of the Glasgow Prognostic Score for glioblastoma multiforme patients treated with radiotherapy and temozolomide.
    Journal of neuro-oncology, 2018, Volume: 139, Issue:2

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Female; Glioblas

2018
Prognostic value of the Glasgow Prognostic Score for glioblastoma multiforme patients treated with radiotherapy and temozolomide.
    Journal of neuro-oncology, 2018, Volume: 139, Issue:2

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Female; Glioblas

2018
Quantitative dynamic susceptibility contrast perfusion-weighted imaging-guided customized gamma knife re-irradiation of recurrent high-grade gliomas.
    Journal of neuro-oncology, 2018, Volume: 139, Issue:1

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Child; Contrast Media;

2018
Quantitative dynamic susceptibility contrast perfusion-weighted imaging-guided customized gamma knife re-irradiation of recurrent high-grade gliomas.
    Journal of neuro-oncology, 2018, Volume: 139, Issue:1

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Child; Contrast Media;

2018
Quantitative dynamic susceptibility contrast perfusion-weighted imaging-guided customized gamma knife re-irradiation of recurrent high-grade gliomas.
    Journal of neuro-oncology, 2018, Volume: 139, Issue:1

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Child; Contrast Media;

2018
Regimen of procarbazine, lomustine, and vincristine versus temozolomide for gliomas.
    Cancer, 2018, 07-01, Volume: 124, Issue:13

    Topics: Adult; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Brain Neop

2018
Regimen of procarbazine, lomustine, and vincristine versus temozolomide for gliomas.
    Cancer, 2018, 07-01, Volume: 124, Issue:13

    Topics: Adult; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Brain Neop

2018
Regimen of procarbazine, lomustine, and vincristine versus temozolomide for gliomas.
    Cancer, 2018, 07-01, Volume: 124, Issue:13

    Topics: Adult; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Brain Neop

2018
Inhibition of NF-κB results in anti-glioma activity and reduces temozolomide-induced chemoresistance by down-regulating MGMT gene expression.
    Cancer letters, 2018, 08-01, Volume: 428

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Brain; Brain Neoplasms; Cell Line, Tumor; D

2018
Inhibition of NF-κB results in anti-glioma activity and reduces temozolomide-induced chemoresistance by down-regulating MGMT gene expression.
    Cancer letters, 2018, 08-01, Volume: 428

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Brain; Brain Neoplasms; Cell Line, Tumor; D

2018
Inhibition of NF-κB results in anti-glioma activity and reduces temozolomide-induced chemoresistance by down-regulating MGMT gene expression.
    Cancer letters, 2018, 08-01, Volume: 428

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Brain; Brain Neoplasms; Cell Line, Tumor; D

2018
Quality of Life in Patients With Glioblastoma Treated With Tumor-Treating Fields.
    JAMA, 2018, 05-01, Volume: 319, Issue:17

    Topics: Adult; Brain Neoplasms; Glioblastoma; Humans; Quality of Life; Temozolomide

2018
Quality of Life in Patients With Glioblastoma Treated With Tumor-Treating Fields.
    JAMA, 2018, 05-01, Volume: 319, Issue:17

    Topics: Adult; Brain Neoplasms; Glioblastoma; Humans; Quality of Life; Temozolomide

2018
Quality of Life in Patients With Glioblastoma Treated With Tumor-Treating Fields.
    JAMA, 2018, 05-01, Volume: 319, Issue:17

    Topics: Adult; Brain Neoplasms; Glioblastoma; Humans; Quality of Life; Temozolomide

2018
Receptor-mediated PLGA nanoparticles for glioblastoma multiforme treatment.
    International journal of pharmaceutics, 2018, Jul-10, Volume: 545, Issue:1-2

    Topics: Antibodies, Monoclonal; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Cell P

2018
Receptor-mediated PLGA nanoparticles for glioblastoma multiforme treatment.
    International journal of pharmaceutics, 2018, Jul-10, Volume: 545, Issue:1-2

    Topics: Antibodies, Monoclonal; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Cell P

2018
Receptor-mediated PLGA nanoparticles for glioblastoma multiforme treatment.
    International journal of pharmaceutics, 2018, Jul-10, Volume: 545, Issue:1-2

    Topics: Antibodies, Monoclonal; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Cell P

2018
MGMT promoter methylation in patients with glioblastoma: is methylation-sensitive high-resolution melting superior to methylation-sensitive polymerase chain reaction assay?
    Journal of neurosurgery, 2018, 05-04, Volume: 130, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Alleles; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Li

2018
MGMT promoter methylation in patients with glioblastoma: is methylation-sensitive high-resolution melting superior to methylation-sensitive polymerase chain reaction assay?
    Journal of neurosurgery, 2018, 05-04, Volume: 130, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Alleles; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Li

2018
MGMT promoter methylation in patients with glioblastoma: is methylation-sensitive high-resolution melting superior to methylation-sensitive polymerase chain reaction assay?
    Journal of neurosurgery, 2018, 05-04, Volume: 130, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Alleles; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Li

2018
Alterations in Cell Motility, Proliferation, and Metabolism in Novel Models of Acquired Temozolomide Resistant Glioblastoma.
    Scientific reports, 2018, 05-08, Volume: 8, Issue:1

    Topics: Actin Cytoskeleton; Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Carmustine; Cell

2018
Alterations in Cell Motility, Proliferation, and Metabolism in Novel Models of Acquired Temozolomide Resistant Glioblastoma.
    Scientific reports, 2018, 05-08, Volume: 8, Issue:1

    Topics: Actin Cytoskeleton; Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Carmustine; Cell

2018
Alterations in Cell Motility, Proliferation, and Metabolism in Novel Models of Acquired Temozolomide Resistant Glioblastoma.
    Scientific reports, 2018, 05-08, Volume: 8, Issue:1

    Topics: Actin Cytoskeleton; Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Carmustine; Cell

2018
Temozolomide rechallenge in recurrent glioblastoma: when is it useful?
    Future oncology (London, England), 2018, Volume: 14, Issue:11

    Topics: Adult; Aged; Brain Neoplasms; Dacarbazine; Disease-Free Survival; Female; Glioblastoma; Humans; Magn

2018
Temozolomide rechallenge in recurrent glioblastoma: when is it useful?
    Future oncology (London, England), 2018, Volume: 14, Issue:11

    Topics: Adult; Aged; Brain Neoplasms; Dacarbazine; Disease-Free Survival; Female; Glioblastoma; Humans; Magn

2018
Temozolomide rechallenge in recurrent glioblastoma: when is it useful?
    Future oncology (London, England), 2018, Volume: 14, Issue:11

    Topics: Adult; Aged; Brain Neoplasms; Dacarbazine; Disease-Free Survival; Female; Glioblastoma; Humans; Magn

2018
Overexpression of Fn14 in gliomas: tumor progression and poor prognosis.
    Future oncology (London, England), 2018, Volume: 14, Issue:13

    Topics: Antineoplastic Agents, Alkylating; Biomarkers, Tumor; Brain; Brain Neoplasms; Cell Line, Tumor; Chem

2018
Overexpression of Fn14 in gliomas: tumor progression and poor prognosis.
    Future oncology (London, England), 2018, Volume: 14, Issue:13

    Topics: Antineoplastic Agents, Alkylating; Biomarkers, Tumor; Brain; Brain Neoplasms; Cell Line, Tumor; Chem

2018
Overexpression of Fn14 in gliomas: tumor progression and poor prognosis.
    Future oncology (London, England), 2018, Volume: 14, Issue:13

    Topics: Antineoplastic Agents, Alkylating; Biomarkers, Tumor; Brain; Brain Neoplasms; Cell Line, Tumor; Chem

2018
Temozolomide combined with PD-1 Antibody therapy for mouse orthotopic glioma model.
    Biochemical and biophysical research communications, 2018, 07-02, Volume: 501, Issue:4

    Topics: Animals; Antibodies, Neoplasm; Brain; Brain Neoplasms; CD4-Positive T-Lymphocytes; CD8-Positive T-Ly

2018
Temozolomide combined with PD-1 Antibody therapy for mouse orthotopic glioma model.
    Biochemical and biophysical research communications, 2018, 07-02, Volume: 501, Issue:4

    Topics: Animals; Antibodies, Neoplasm; Brain; Brain Neoplasms; CD4-Positive T-Lymphocytes; CD8-Positive T-Ly

2018
Temozolomide combined with PD-1 Antibody therapy for mouse orthotopic glioma model.
    Biochemical and biophysical research communications, 2018, 07-02, Volume: 501, Issue:4

    Topics: Animals; Antibodies, Neoplasm; Brain; Brain Neoplasms; CD4-Positive T-Lymphocytes; CD8-Positive T-Ly

2018
[Clinical efficacy of stereotactic radiation therapy combined with temozolomide on recurrent brain glioma].
    Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences, 2018, Apr-28, Volume: 43, Issue:4

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Combined Modality Therapy; Da

2018
[Clinical efficacy of stereotactic radiation therapy combined with temozolomide on recurrent brain glioma].
    Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences, 2018, Apr-28, Volume: 43, Issue:4

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Combined Modality Therapy; Da

2018
[Clinical efficacy of stereotactic radiation therapy combined with temozolomide on recurrent brain glioma].
    Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences, 2018, Apr-28, Volume: 43, Issue:4

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Combined Modality Therapy; Da

2018
Enhanced efficacy of combined temozolomide and bromodomain inhibitor therapy for gliomas using targeted nanoparticles.
    Nature communications, 2018, 05-18, Volume: 9, Issue:1

    Topics: Animals; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Apoptosis; Azepines; Blood-Brain

2018
Enhanced efficacy of combined temozolomide and bromodomain inhibitor therapy for gliomas using targeted nanoparticles.
    Nature communications, 2018, 05-18, Volume: 9, Issue:1

    Topics: Animals; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Apoptosis; Azepines; Blood-Brain

2018
Enhanced efficacy of combined temozolomide and bromodomain inhibitor therapy for gliomas using targeted nanoparticles.
    Nature communications, 2018, 05-18, Volume: 9, Issue:1

    Topics: Animals; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Apoptosis; Azepines; Blood-Brain

2018
Patterns of care and outcomes of chemoradiation versus radiation alone for MGMT promoter unmethylated glioblastoma.
    Clinical neurology and neurosurgery, 2018, Volume: 170

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Cohort Studies; Databases, Fa

2018
Patterns of care and outcomes of chemoradiation versus radiation alone for MGMT promoter unmethylated glioblastoma.
    Clinical neurology and neurosurgery, 2018, Volume: 170

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Cohort Studies; Databases, Fa

2018
Patterns of care and outcomes of chemoradiation versus radiation alone for MGMT promoter unmethylated glioblastoma.
    Clinical neurology and neurosurgery, 2018, Volume: 170

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Cohort Studies; Databases, Fa

2018
Down-regulation of MDR1 by Ad-DKK3 via Akt/NFκB pathways augments the anti-tumor effect of temozolomide in glioblastoma cells and a murine xenograft model.
    Journal of neuro-oncology, 2018, Volume: 139, Issue:2

    Topics: Animals; Antineoplastic Agents, Alkylating; ATP Binding Cassette Transporter, Subfamily B, Member 1;

2018
Down-regulation of MDR1 by Ad-DKK3 via Akt/NFκB pathways augments the anti-tumor effect of temozolomide in glioblastoma cells and a murine xenograft model.
    Journal of neuro-oncology, 2018, Volume: 139, Issue:2

    Topics: Animals; Antineoplastic Agents, Alkylating; ATP Binding Cassette Transporter, Subfamily B, Member 1;

2018
Down-regulation of MDR1 by Ad-DKK3 via Akt/NFκB pathways augments the anti-tumor effect of temozolomide in glioblastoma cells and a murine xenograft model.
    Journal of neuro-oncology, 2018, Volume: 139, Issue:2

    Topics: Animals; Antineoplastic Agents, Alkylating; ATP Binding Cassette Transporter, Subfamily B, Member 1;

2018
Regulation of the oxidative balance with coenzyme Q10 sensitizes human glioblastoma cells to radiation and temozolomide.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2018, Volume: 128, Issue:2

    Topics: Antioxidants; Apoptosis; Brain Neoplasms; Dacarbazine; DNA Damage; Glioblastoma; Humans; Hydrogen Pe

2018
Regulation of the oxidative balance with coenzyme Q10 sensitizes human glioblastoma cells to radiation and temozolomide.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2018, Volume: 128, Issue:2

    Topics: Antioxidants; Apoptosis; Brain Neoplasms; Dacarbazine; DNA Damage; Glioblastoma; Humans; Hydrogen Pe

2018
Regulation of the oxidative balance with coenzyme Q10 sensitizes human glioblastoma cells to radiation and temozolomide.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2018, Volume: 128, Issue:2

    Topics: Antioxidants; Apoptosis; Brain Neoplasms; Dacarbazine; DNA Damage; Glioblastoma; Humans; Hydrogen Pe

2018
Role of Molecular Pathology in the Treatment of Anaplastic Gliomas and Glioblastomas.
    Journal of the National Comprehensive Cancer Network : JNCCN, 2018, Volume: 16, Issue:5S

    Topics: Antineoplastic Agents, Alkylating; Biomarkers, Tumor; Brain; Brain Neoplasms; Chemoradiotherapy, Adj

2018
Role of Molecular Pathology in the Treatment of Anaplastic Gliomas and Glioblastomas.
    Journal of the National Comprehensive Cancer Network : JNCCN, 2018, Volume: 16, Issue:5S

    Topics: Antineoplastic Agents, Alkylating; Biomarkers, Tumor; Brain; Brain Neoplasms; Chemoradiotherapy, Adj

2018
Role of Molecular Pathology in the Treatment of Anaplastic Gliomas and Glioblastomas.
    Journal of the National Comprehensive Cancer Network : JNCCN, 2018, Volume: 16, Issue:5S

    Topics: Antineoplastic Agents, Alkylating; Biomarkers, Tumor; Brain; Brain Neoplasms; Chemoradiotherapy, Adj

2018
Superselective intraarterial cerebral infusion of cetuximab with blood brain barrier disruption combined with Stupp Protocol for newly diagnosed glioblastoma.
    Journal of experimental therapeutics & oncology, 2018, Volume: 12, Issue:3

    Topics: Angiography, Digital Subtraction; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Immunolo

2018
Superselective intraarterial cerebral infusion of cetuximab with blood brain barrier disruption combined with Stupp Protocol for newly diagnosed glioblastoma.
    Journal of experimental therapeutics & oncology, 2018, Volume: 12, Issue:3

    Topics: Angiography, Digital Subtraction; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Immunolo

2018
Superselective intraarterial cerebral infusion of cetuximab with blood brain barrier disruption combined with Stupp Protocol for newly diagnosed glioblastoma.
    Journal of experimental therapeutics & oncology, 2018, Volume: 12, Issue:3

    Topics: Angiography, Digital Subtraction; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Immunolo

2018
Treatment outcomes of hypofractionated radiotherapy combined with temozolomide followed by bevacizumab salvage therapy in glioblastoma patients aged > 75 years.
    International journal of clinical oncology, 2018, Volume: 23, Issue:5

    Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Brain Neoplasm

2018
Treatment outcomes of hypofractionated radiotherapy combined with temozolomide followed by bevacizumab salvage therapy in glioblastoma patients aged > 75 years.
    International journal of clinical oncology, 2018, Volume: 23, Issue:5

    Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Brain Neoplasm

2018
Treatment outcomes of hypofractionated radiotherapy combined with temozolomide followed by bevacizumab salvage therapy in glioblastoma patients aged > 75 years.
    International journal of clinical oncology, 2018, Volume: 23, Issue:5

    Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Brain Neoplasm

2018
Memory and attention recovery in patients with High Grade Glioma who completed the Stupp protocol: A before-after study.
    Clinical neurology and neurosurgery, 2018, Volume: 171

    Topics: Adult; Aged; Attention; Brain Neoplasms; Cognition; Combined Modality Therapy; Dacarbazine; Female;

2018
Memory and attention recovery in patients with High Grade Glioma who completed the Stupp protocol: A before-after study.
    Clinical neurology and neurosurgery, 2018, Volume: 171

    Topics: Adult; Aged; Attention; Brain Neoplasms; Cognition; Combined Modality Therapy; Dacarbazine; Female;

2018
Memory and attention recovery in patients with High Grade Glioma who completed the Stupp protocol: A before-after study.
    Clinical neurology and neurosurgery, 2018, Volume: 171

    Topics: Adult; Aged; Attention; Brain Neoplasms; Cognition; Combined Modality Therapy; Dacarbazine; Female;

2018
Identification of a DNA Repair-Related Multigene Signature as a Novel Prognostic Predictor of Glioblastoma.
    World neurosurgery, 2018, Volume: 117

    Topics: Adenine Phosphoribosyltransferase; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms;

2018
Identification of a DNA Repair-Related Multigene Signature as a Novel Prognostic Predictor of Glioblastoma.
    World neurosurgery, 2018, Volume: 117

    Topics: Adenine Phosphoribosyltransferase; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms;

2018
Identification of a DNA Repair-Related Multigene Signature as a Novel Prognostic Predictor of Glioblastoma.
    World neurosurgery, 2018, Volume: 117

    Topics: Adenine Phosphoribosyltransferase; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms;

2018
Synergistic Anticancer Effects of Formononetin and Temozolomide on Glioma C6 Cells.
    Biological & pharmaceutical bulletin, 2018, Aug-01, Volume: 41, Issue:8

    Topics: Animals; Antineoplastic Agents; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Dr

2018
Synergistic Anticancer Effects of Formononetin and Temozolomide on Glioma C6 Cells.
    Biological & pharmaceutical bulletin, 2018, Aug-01, Volume: 41, Issue:8

    Topics: Animals; Antineoplastic Agents; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Dr

2018
Synergistic Anticancer Effects of Formononetin and Temozolomide on Glioma C6 Cells.
    Biological & pharmaceutical bulletin, 2018, Aug-01, Volume: 41, Issue:8

    Topics: Animals; Antineoplastic Agents; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Dr

2018
Lactoferrin- and RGD-comodified, temozolomide and vincristine-coloaded nanostructured lipid carriers for gliomatosis cerebri combination therapy.
    International journal of nanomedicine, 2018, Volume: 13

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Cell Line, Tumor; Dacarbaz

2018
Lactoferrin- and RGD-comodified, temozolomide and vincristine-coloaded nanostructured lipid carriers for gliomatosis cerebri combination therapy.
    International journal of nanomedicine, 2018, Volume: 13

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Cell Line, Tumor; Dacarbaz

2018
Lactoferrin- and RGD-comodified, temozolomide and vincristine-coloaded nanostructured lipid carriers for gliomatosis cerebri combination therapy.
    International journal of nanomedicine, 2018, Volume: 13

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Cell Line, Tumor; Dacarbaz

2018
miR-1268a regulates ABCC1 expression to mediate temozolomide resistance in glioblastoma.
    Journal of neuro-oncology, 2018, Volume: 138, Issue:3

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; G

2018
miR-1268a regulates ABCC1 expression to mediate temozolomide resistance in glioblastoma.
    Journal of neuro-oncology, 2018, Volume: 138, Issue:3

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; G

2018
miR-1268a regulates ABCC1 expression to mediate temozolomide resistance in glioblastoma.
    Journal of neuro-oncology, 2018, Volume: 138, Issue:3

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; G

2018
Improved survival of Swedish glioblastoma patients treated according to Stupp.
    Acta neurologica Scandinavica, 2018, Volume: 138, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cohort Studies;

2018
Improved survival of Swedish glioblastoma patients treated according to Stupp.
    Acta neurologica Scandinavica, 2018, Volume: 138, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cohort Studies;

2018
Improved survival of Swedish glioblastoma patients treated according to Stupp.
    Acta neurologica Scandinavica, 2018, Volume: 138, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cohort Studies;

2018
Elevation of the TP53 isoform Δ133p53β in glioblastomas: an alternative to mutant p53 in promoting tumor development.
    The Journal of pathology, 2018, Volume: 246, Issue:1

    Topics: Animals; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Antineoplastic Agents, Alkylating;

2018
Elevation of the TP53 isoform Δ133p53β in glioblastomas: an alternative to mutant p53 in promoting tumor development.
    The Journal of pathology, 2018, Volume: 246, Issue:1

    Topics: Animals; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Antineoplastic Agents, Alkylating;

2018
Elevation of the TP53 isoform Δ133p53β in glioblastomas: an alternative to mutant p53 in promoting tumor development.
    The Journal of pathology, 2018, Volume: 246, Issue:1

    Topics: Animals; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Antineoplastic Agents, Alkylating;

2018
Fabrication and Characterization of Chitosan-Hyaluronic Acid Scaffolds with Varying Stiffness for Glioblastoma Cell Culture.
    Advanced healthcare materials, 2018, Volume: 7, Issue:15

    Topics: Antineoplastic Agents; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Chitosan; Glioblastoma

2018
Fabrication and Characterization of Chitosan-Hyaluronic Acid Scaffolds with Varying Stiffness for Glioblastoma Cell Culture.
    Advanced healthcare materials, 2018, Volume: 7, Issue:15

    Topics: Antineoplastic Agents; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Chitosan; Glioblastoma

2018
Fabrication and Characterization of Chitosan-Hyaluronic Acid Scaffolds with Varying Stiffness for Glioblastoma Cell Culture.
    Advanced healthcare materials, 2018, Volume: 7, Issue:15

    Topics: Antineoplastic Agents; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Chitosan; Glioblastoma

2018
The TNF receptor family member Fn14 is highly expressed in recurrent glioblastoma and in GBM patient-derived xenografts with acquired temozolomide resistance.
    Neuro-oncology, 2018, 09-03, Volume: 20, Issue:10

    Topics: Animals; Antineoplastic Agents, Alkylating; Apoptosis; Biomarkers, Tumor; Brain Neoplasms; Cell Move

2018
The TNF receptor family member Fn14 is highly expressed in recurrent glioblastoma and in GBM patient-derived xenografts with acquired temozolomide resistance.
    Neuro-oncology, 2018, 09-03, Volume: 20, Issue:10

    Topics: Animals; Antineoplastic Agents, Alkylating; Apoptosis; Biomarkers, Tumor; Brain Neoplasms; Cell Move

2018
The TNF receptor family member Fn14 is highly expressed in recurrent glioblastoma and in GBM patient-derived xenografts with acquired temozolomide resistance.
    Neuro-oncology, 2018, 09-03, Volume: 20, Issue:10

    Topics: Animals; Antineoplastic Agents, Alkylating; Apoptosis; Biomarkers, Tumor; Brain Neoplasms; Cell Move

2018
[Establishment of a glioma orthotopic xenograft model based on imaging technology].
    Yao xue xue bao = Acta pharmaceutica Sinica, 2016, Volume: 51, Issue:8

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Dacarbazine; Disease

2016
[Establishment of a glioma orthotopic xenograft model based on imaging technology].
    Yao xue xue bao = Acta pharmaceutica Sinica, 2016, Volume: 51, Issue:8

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Dacarbazine; Disease

2016
[Establishment of a glioma orthotopic xenograft model based on imaging technology].
    Yao xue xue bao = Acta pharmaceutica Sinica, 2016, Volume: 51, Issue:8

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Dacarbazine; Disease

2016
USE OF PERFUSION MRI FOR DETERMINATION OF IRRADIATION VOLUMES IN RADIOTHERAPY OF PATIENTS WITH BRAIN GLIOMA.
    Georgian medical news, 2018, Issue:278

    Topics: Antineoplastic Agents, Alkylating; Brain; Brain Neoplasms; Contrast Media; Diffusion Magnetic Resona

2018
USE OF PERFUSION MRI FOR DETERMINATION OF IRRADIATION VOLUMES IN RADIOTHERAPY OF PATIENTS WITH BRAIN GLIOMA.
    Georgian medical news, 2018, Issue:278

    Topics: Antineoplastic Agents, Alkylating; Brain; Brain Neoplasms; Contrast Media; Diffusion Magnetic Resona

2018
USE OF PERFUSION MRI FOR DETERMINATION OF IRRADIATION VOLUMES IN RADIOTHERAPY OF PATIENTS WITH BRAIN GLIOMA.
    Georgian medical news, 2018, Issue:278

    Topics: Antineoplastic Agents, Alkylating; Brain; Brain Neoplasms; Contrast Media; Diffusion Magnetic Resona

2018
Tumor-treating fields: time for demystification.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2018, 08-01, Volume: 29, Issue:8

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Electric Stimulation

2018
Tumor-treating fields: time for demystification.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2018, 08-01, Volume: 29, Issue:8

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Electric Stimulation

2018
Tumor-treating fields: time for demystification.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2018, 08-01, Volume: 29, Issue:8

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Electric Stimulation

2018
Combination with TMZ and miR-505 inhibits the development of glioblastoma by regulating the WNT7B/Wnt/β-catenin signaling pathway.
    Gene, 2018, Sep-25, Volume: 672

    Topics: Animals; Antineoplastic Agents, Alkylating; Base Sequence; beta Catenin; Binding Sites; Brain Neopla

2018
Combination with TMZ and miR-505 inhibits the development of glioblastoma by regulating the WNT7B/Wnt/β-catenin signaling pathway.
    Gene, 2018, Sep-25, Volume: 672

    Topics: Animals; Antineoplastic Agents, Alkylating; Base Sequence; beta Catenin; Binding Sites; Brain Neopla

2018
Combination with TMZ and miR-505 inhibits the development of glioblastoma by regulating the WNT7B/Wnt/β-catenin signaling pathway.
    Gene, 2018, Sep-25, Volume: 672

    Topics: Animals; Antineoplastic Agents, Alkylating; Base Sequence; beta Catenin; Binding Sites; Brain Neopla

2018
High expression of a novel splicing variant of VEGF, L-VEGF144 in glioblastoma multiforme is associated with a poorer prognosis in bevacizumab treatment.
    Journal of neuro-oncology, 2018, Volume: 140, Issue:1

    Topics: Adult; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Immunological; Bevacizumab; Brain N

2018
High expression of a novel splicing variant of VEGF, L-VEGF144 in glioblastoma multiforme is associated with a poorer prognosis in bevacizumab treatment.
    Journal of neuro-oncology, 2018, Volume: 140, Issue:1

    Topics: Adult; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Immunological; Bevacizumab; Brain N

2018
High expression of a novel splicing variant of VEGF, L-VEGF144 in glioblastoma multiforme is associated with a poorer prognosis in bevacizumab treatment.
    Journal of neuro-oncology, 2018, Volume: 140, Issue:1

    Topics: Adult; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Immunological; Bevacizumab; Brain N

2018
Clinical and Molecular Recursive Partitioning Analysis of High-grade Glioma Treated With IMRT.
    American journal of clinical oncology, 2019, Volume: 42, Issue:1

    Topics: Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chromosome Deletion; DNA Methylation; DNA

2019
Clinical and Molecular Recursive Partitioning Analysis of High-grade Glioma Treated With IMRT.
    American journal of clinical oncology, 2019, Volume: 42, Issue:1

    Topics: Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chromosome Deletion; DNA Methylation; DNA

2019
Clinical and Molecular Recursive Partitioning Analysis of High-grade Glioma Treated With IMRT.
    American journal of clinical oncology, 2019, Volume: 42, Issue:1

    Topics: Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chromosome Deletion; DNA Methylation; DNA

2019
Efficacy of D,L-methadone in the treatment of glioblastoma in vitro.
    CNS oncology, 2018, 07-01, Volume: 7, Issue:3

    Topics: Adult; Analgesics, Opioid; Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cell Line,

2018
Efficacy of D,L-methadone in the treatment of glioblastoma in vitro.
    CNS oncology, 2018, 07-01, Volume: 7, Issue:3

    Topics: Adult; Analgesics, Opioid; Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cell Line,

2018
Efficacy of D,L-methadone in the treatment of glioblastoma in vitro.
    CNS oncology, 2018, 07-01, Volume: 7, Issue:3

    Topics: Adult; Analgesics, Opioid; Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cell Line,

2018
Getting to the brain.
    Nature nanotechnology, 2018, Volume: 13, Issue:7

    Topics: Animals; Antineoplastic Agents; Azepines; Blood-Brain Barrier; Brain; Brain Neoplasms; Drug Carriers

2018
Getting to the brain.
    Nature nanotechnology, 2018, Volume: 13, Issue:7

    Topics: Animals; Antineoplastic Agents; Azepines; Blood-Brain Barrier; Brain; Brain Neoplasms; Drug Carriers

2018
Getting to the brain.
    Nature nanotechnology, 2018, Volume: 13, Issue:7

    Topics: Animals; Antineoplastic Agents; Azepines; Blood-Brain Barrier; Brain; Brain Neoplasms; Drug Carriers

2018
Clinical correlates of severe thrombocytopenia from temozolomide in glioblastoma patients.
    Internal medicine journal, 2018, Volume: 48, Issue:10

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Ad

2018
Clinical correlates of severe thrombocytopenia from temozolomide in glioblastoma patients.
    Internal medicine journal, 2018, Volume: 48, Issue:10

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Ad

2018
Clinical correlates of severe thrombocytopenia from temozolomide in glioblastoma patients.
    Internal medicine journal, 2018, Volume: 48, Issue:10

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Ad

2018
Euphol, a tetracyclic triterpene, from Euphorbia tirucalli induces autophagy and sensitizes temozolomide cytotoxicity on glioblastoma cells.
    Investigational new drugs, 2019, Volume: 37, Issue:2

    Topics: Antineoplastic Agents, Alkylating; Apoptosis; Autophagy; Brain Neoplasms; Cell Movement; Cell Prolif

2019
Euphol, a tetracyclic triterpene, from Euphorbia tirucalli induces autophagy and sensitizes temozolomide cytotoxicity on glioblastoma cells.
    Investigational new drugs, 2019, Volume: 37, Issue:2

    Topics: Antineoplastic Agents, Alkylating; Apoptosis; Autophagy; Brain Neoplasms; Cell Movement; Cell Prolif

2019
Euphol, a tetracyclic triterpene, from Euphorbia tirucalli induces autophagy and sensitizes temozolomide cytotoxicity on glioblastoma cells.
    Investigational new drugs, 2019, Volume: 37, Issue:2

    Topics: Antineoplastic Agents, Alkylating; Apoptosis; Autophagy; Brain Neoplasms; Cell Movement; Cell Prolif

2019
Perivascular signals alter global gene expression profile of glioblastoma and response to temozolomide in a gelatin hydrogel.
    Biomaterials, 2019, Volume: 198

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line; Cell Line, Tumor; Drug Delivery Syste

2019
Perivascular signals alter global gene expression profile of glioblastoma and response to temozolomide in a gelatin hydrogel.
    Biomaterials, 2019, Volume: 198

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line; Cell Line, Tumor; Drug Delivery Syste

2019
Perivascular signals alter global gene expression profile of glioblastoma and response to temozolomide in a gelatin hydrogel.
    Biomaterials, 2019, Volume: 198

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line; Cell Line, Tumor; Drug Delivery Syste

2019
Effectiveness of temozolomide combined with whole brain radiotherapy for non-small cell lung cancer brain metastases.
    Thoracic cancer, 2018, Volume: 9, Issue:9

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Biomarkers; Brain Neoplasms; Carcinoma,

2018
Effectiveness of temozolomide combined with whole brain radiotherapy for non-small cell lung cancer brain metastases.
    Thoracic cancer, 2018, Volume: 9, Issue:9

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Biomarkers; Brain Neoplasms; Carcinoma,

2018
Effectiveness of temozolomide combined with whole brain radiotherapy for non-small cell lung cancer brain metastases.
    Thoracic cancer, 2018, Volume: 9, Issue:9

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Biomarkers; Brain Neoplasms; Carcinoma,

2018
[
    Molecular imaging and biology, 2019, Volume: 21, Issue:2

    Topics: Animals; Bevacizumab; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Disease Models, Animal;

2019
[
    Molecular imaging and biology, 2019, Volume: 21, Issue:2

    Topics: Animals; Bevacizumab; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Disease Models, Animal;

2019
[
    Molecular imaging and biology, 2019, Volume: 21, Issue:2

    Topics: Animals; Bevacizumab; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Disease Models, Animal;

2019
C1q/TNF-related peptide 8 (CTRP8) promotes temozolomide resistance in human glioblastoma.
    Molecular oncology, 2018, Volume: 12, Issue:9

    Topics: Adiponectin; Antineoplastic Agents, Alkylating; Apoptosis; bcl-X Protein; Brain Neoplasms; Caspase 3

2018
C1q/TNF-related peptide 8 (CTRP8) promotes temozolomide resistance in human glioblastoma.
    Molecular oncology, 2018, Volume: 12, Issue:9

    Topics: Adiponectin; Antineoplastic Agents, Alkylating; Apoptosis; bcl-X Protein; Brain Neoplasms; Caspase 3

2018
C1q/TNF-related peptide 8 (CTRP8) promotes temozolomide resistance in human glioblastoma.
    Molecular oncology, 2018, Volume: 12, Issue:9

    Topics: Adiponectin; Antineoplastic Agents, Alkylating; Apoptosis; bcl-X Protein; Brain Neoplasms; Caspase 3

2018
Genetic variants related to angiogenesis and apoptosis in patients with glioma.
    Arquivos de neuro-psiquiatria, 2018, Volume: 76, Issue:6

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Apoptosis; Brain Neop

2018
Genetic variants related to angiogenesis and apoptosis in patients with glioma.
    Arquivos de neuro-psiquiatria, 2018, Volume: 76, Issue:6

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Apoptosis; Brain Neop

2018
Genetic variants related to angiogenesis and apoptosis in patients with glioma.
    Arquivos de neuro-psiquiatria, 2018, Volume: 76, Issue:6

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Apoptosis; Brain Neop

2018
    Science translational medicine, 2018, 07-04, Volume: 10, Issue:448

    Topics: Antineoplastic Agents, Alkylating; B-Cell Lymphoma 3 Protein; Brain Neoplasms; Carbonic Anhydrase II

2018
    Science translational medicine, 2018, 07-04, Volume: 10, Issue:448

    Topics: Antineoplastic Agents, Alkylating; B-Cell Lymphoma 3 Protein; Brain Neoplasms; Carbonic Anhydrase II

2018
    Science translational medicine, 2018, 07-04, Volume: 10, Issue:448

    Topics: Antineoplastic Agents, Alkylating; B-Cell Lymphoma 3 Protein; Brain Neoplasms; Carbonic Anhydrase II

2018
Early platelet variation during concomitant chemo-radiotherapy predicts adjuvant temozolomide-induced thrombocytopenia in newly diagnosed glioblastoma patients.
    Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2019, Volume: 27, Issue:2

    Topics: Aged; Antineoplastic Agents, Alkylating; Blood Platelets; Brain Neoplasms; Chemoradiotherapy; Female

2019
Early platelet variation during concomitant chemo-radiotherapy predicts adjuvant temozolomide-induced thrombocytopenia in newly diagnosed glioblastoma patients.
    Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2019, Volume: 27, Issue:2

    Topics: Aged; Antineoplastic Agents, Alkylating; Blood Platelets; Brain Neoplasms; Chemoradiotherapy; Female

2019
Early platelet variation during concomitant chemo-radiotherapy predicts adjuvant temozolomide-induced thrombocytopenia in newly diagnosed glioblastoma patients.
    Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2019, Volume: 27, Issue:2

    Topics: Aged; Antineoplastic Agents, Alkylating; Blood Platelets; Brain Neoplasms; Chemoradiotherapy; Female

2019
Coordinated autophagy modulation overcomes glioblastoma chemoresistance through disruption of mitochondrial bioenergetics.
    Scientific reports, 2018, 07-09, Volume: 8, Issue:1

    Topics: Antineoplastic Agents; Autophagy; Autophagy-Related Protein 5; Brain Neoplasms; Cell Line, Tumor; Ce

2018
Coordinated autophagy modulation overcomes glioblastoma chemoresistance through disruption of mitochondrial bioenergetics.
    Scientific reports, 2018, 07-09, Volume: 8, Issue:1

    Topics: Antineoplastic Agents; Autophagy; Autophagy-Related Protein 5; Brain Neoplasms; Cell Line, Tumor; Ce

2018
Coordinated autophagy modulation overcomes glioblastoma chemoresistance through disruption of mitochondrial bioenergetics.
    Scientific reports, 2018, 07-09, Volume: 8, Issue:1

    Topics: Antineoplastic Agents; Autophagy; Autophagy-Related Protein 5; Brain Neoplasms; Cell Line, Tumor; Ce

2018
Cell surface vimentin-targeted monoclonal antibody 86C increases sensitivity to temozolomide in glioma stem cells.
    Cancer letters, 2018, 10-01, Volume: 433

    Topics: Animals; Antibodies, Monoclonal; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Ce

2018
Cell surface vimentin-targeted monoclonal antibody 86C increases sensitivity to temozolomide in glioma stem cells.
    Cancer letters, 2018, 10-01, Volume: 433

    Topics: Animals; Antibodies, Monoclonal; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Ce

2018
Cell surface vimentin-targeted monoclonal antibody 86C increases sensitivity to temozolomide in glioma stem cells.
    Cancer letters, 2018, 10-01, Volume: 433

    Topics: Animals; Antibodies, Monoclonal; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Ce

2018
Data-Driven Predictive Models of Diffuse Low-Grade Gliomas Under Chemotherapy.
    IEEE journal of biomedical and health informatics, 2019, Volume: 23, Issue:1

    Topics: Algorithms; Antineoplastic Agents; Brain; Brain Neoplasms; Computational Biology; Glioma; Humans; Ma

2019
Data-Driven Predictive Models of Diffuse Low-Grade Gliomas Under Chemotherapy.
    IEEE journal of biomedical and health informatics, 2019, Volume: 23, Issue:1

    Topics: Algorithms; Antineoplastic Agents; Brain; Brain Neoplasms; Computational Biology; Glioma; Humans; Ma

2019
Data-Driven Predictive Models of Diffuse Low-Grade Gliomas Under Chemotherapy.
    IEEE journal of biomedical and health informatics, 2019, Volume: 23, Issue:1

    Topics: Algorithms; Antineoplastic Agents; Brain; Brain Neoplasms; Computational Biology; Glioma; Humans; Ma

2019
Verapamil potentiates anti-glioblastoma efficacy of temozolomide by modulating apoptotic signaling.
    Toxicology in vitro : an international journal published in association with BIBRA, 2018, Volume: 52

    Topics: Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Dacarbazine; Drug S

2018
Verapamil potentiates anti-glioblastoma efficacy of temozolomide by modulating apoptotic signaling.
    Toxicology in vitro : an international journal published in association with BIBRA, 2018, Volume: 52

    Topics: Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Dacarbazine; Drug S

2018
Verapamil potentiates anti-glioblastoma efficacy of temozolomide by modulating apoptotic signaling.
    Toxicology in vitro : an international journal published in association with BIBRA, 2018, Volume: 52

    Topics: Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Dacarbazine; Drug S

2018
Delivery of MGMT mRNA to glioma cells by reactive astrocyte-derived exosomes confers a temozolomide resistance phenotype.
    Cancer letters, 2018, 10-01, Volume: 433

    Topics: Antineoplastic Agents, Alkylating; Apoptosis; Astrocytes; Brain Neoplasms; Cell Line, Tumor; DNA Mod

2018
Delivery of MGMT mRNA to glioma cells by reactive astrocyte-derived exosomes confers a temozolomide resistance phenotype.
    Cancer letters, 2018, 10-01, Volume: 433

    Topics: Antineoplastic Agents, Alkylating; Apoptosis; Astrocytes; Brain Neoplasms; Cell Line, Tumor; DNA Mod

2018
Delivery of MGMT mRNA to glioma cells by reactive astrocyte-derived exosomes confers a temozolomide resistance phenotype.
    Cancer letters, 2018, 10-01, Volume: 433

    Topics: Antineoplastic Agents, Alkylating; Apoptosis; Astrocytes; Brain Neoplasms; Cell Line, Tumor; DNA Mod

2018
Brain Targeting by Liposome-Biomolecular Corona Boosts Anticancer Efficacy of Temozolomide in Glioblastoma Cells.
    ACS chemical neuroscience, 2018, 12-19, Volume: 9, Issue:12

    Topics: Antineoplastic Agents, Alkylating; Apolipoproteins; Blood-Brain Barrier; Brain; Brain Neoplasms; Cel

2018
Brain Targeting by Liposome-Biomolecular Corona Boosts Anticancer Efficacy of Temozolomide in Glioblastoma Cells.
    ACS chemical neuroscience, 2018, 12-19, Volume: 9, Issue:12

    Topics: Antineoplastic Agents, Alkylating; Apolipoproteins; Blood-Brain Barrier; Brain; Brain Neoplasms; Cel

2018
Brain Targeting by Liposome-Biomolecular Corona Boosts Anticancer Efficacy of Temozolomide in Glioblastoma Cells.
    ACS chemical neuroscience, 2018, 12-19, Volume: 9, Issue:12

    Topics: Antineoplastic Agents, Alkylating; Apolipoproteins; Blood-Brain Barrier; Brain; Brain Neoplasms; Cel

2018
Dehydroepiandrosterone Induces Temozolomide Resistance Through Modulating Phosphorylation and Acetylation of Sp1 in Glioblastoma.
    Molecular neurobiology, 2019, Volume: 56, Issue:4

    Topics: Acetylation; Brain Neoplasms; Cell Line, Tumor; Cell Nucleus; Dehydroepiandrosterone; DNA Damage; Dr

2019
Dehydroepiandrosterone Induces Temozolomide Resistance Through Modulating Phosphorylation and Acetylation of Sp1 in Glioblastoma.
    Molecular neurobiology, 2019, Volume: 56, Issue:4

    Topics: Acetylation; Brain Neoplasms; Cell Line, Tumor; Cell Nucleus; Dehydroepiandrosterone; DNA Damage; Dr

2019
Dehydroepiandrosterone Induces Temozolomide Resistance Through Modulating Phosphorylation and Acetylation of Sp1 in Glioblastoma.
    Molecular neurobiology, 2019, Volume: 56, Issue:4

    Topics: Acetylation; Brain Neoplasms; Cell Line, Tumor; Cell Nucleus; Dehydroepiandrosterone; DNA Damage; Dr

2019
The prognostic improvement of add-on bevacizumab for progressive disease during concomitant temozolomide and radiation therapy in patients with glioblastoma and anaplastic astrocytoma.
    Journal of neurosurgical sciences, 2020, Volume: 64, Issue:6

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Brain Neoplasms; Glioblastoma; Humans;

2020
The prognostic improvement of add-on bevacizumab for progressive disease during concomitant temozolomide and radiation therapy in patients with glioblastoma and anaplastic astrocytoma.
    Journal of neurosurgical sciences, 2020, Volume: 64, Issue:6

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Brain Neoplasms; Glioblastoma; Humans;

2020
The prognostic improvement of add-on bevacizumab for progressive disease during concomitant temozolomide and radiation therapy in patients with glioblastoma and anaplastic astrocytoma.
    Journal of neurosurgical sciences, 2020, Volume: 64, Issue:6

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Brain Neoplasms; Glioblastoma; Humans;

2020
Associations of anticoagulant use with outcome in newly diagnosed glioblastoma.
    European journal of cancer (Oxford, England : 1990), 2018, Volume: 101

    Topics: Anticoagulants; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; B

2018
Associations of anticoagulant use with outcome in newly diagnosed glioblastoma.
    European journal of cancer (Oxford, England : 1990), 2018, Volume: 101

    Topics: Anticoagulants; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; B

2018
Associations of anticoagulant use with outcome in newly diagnosed glioblastoma.
    European journal of cancer (Oxford, England : 1990), 2018, Volume: 101

    Topics: Anticoagulants; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; B

2018
A multi-sequence and habitat-based MRI radiomics signature for preoperative prediction of MGMT promoter methylation in astrocytomas with prognostic implication.
    European radiology, 2019, Volume: 29, Issue:2

    Topics: Antineoplastic Agents, Alkylating; Astrocytoma; Biomarkers, Tumor; Brain Neoplasms; DNA Methylation;

2019
A multi-sequence and habitat-based MRI radiomics signature for preoperative prediction of MGMT promoter methylation in astrocytomas with prognostic implication.
    European radiology, 2019, Volume: 29, Issue:2

    Topics: Antineoplastic Agents, Alkylating; Astrocytoma; Biomarkers, Tumor; Brain Neoplasms; DNA Methylation;

2019
A multi-sequence and habitat-based MRI radiomics signature for preoperative prediction of MGMT promoter methylation in astrocytomas with prognostic implication.
    European radiology, 2019, Volume: 29, Issue:2

    Topics: Antineoplastic Agents, Alkylating; Astrocytoma; Biomarkers, Tumor; Brain Neoplasms; DNA Methylation;

2019
Modulation of Cell State to Improve Drug Therapy.
    CPT: pharmacometrics & systems pharmacology, 2018, Volume: 7, Issue:9

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Humans; Mo

2018
Modulation of Cell State to Improve Drug Therapy.
    CPT: pharmacometrics & systems pharmacology, 2018, Volume: 7, Issue:9

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Humans; Mo

2018
Modulation of Cell State to Improve Drug Therapy.
    CPT: pharmacometrics & systems pharmacology, 2018, Volume: 7, Issue:9

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Humans; Mo

2018
Newcastle disease virus enhances the growth-inhibiting and proapoptotic effects of temozolomide on glioblastoma cells in vitro and in vivo.
    Scientific reports, 2018, 07-31, Volume: 8, Issue:1

    Topics: AMP-Activated Protein Kinases; Animals; Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasm

2018
Newcastle disease virus enhances the growth-inhibiting and proapoptotic effects of temozolomide on glioblastoma cells in vitro and in vivo.
    Scientific reports, 2018, 07-31, Volume: 8, Issue:1

    Topics: AMP-Activated Protein Kinases; Animals; Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasm

2018
Newcastle disease virus enhances the growth-inhibiting and proapoptotic effects of temozolomide on glioblastoma cells in vitro and in vivo.
    Scientific reports, 2018, 07-31, Volume: 8, Issue:1

    Topics: AMP-Activated Protein Kinases; Animals; Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasm

2018
Successful Novel Treatment of a Paraspinal Primitive Neuroectodermal Tumor with Predominantly Glial Differentiation: A 3-Year Follow-Up After Surgery, Intensity-Modulated Radiation Therapy and Oral Temozolomide.
    World neurosurgery, 2018, Volume: 119

    Topics: Administration, Oral; Antineoplastic Agents, Alkylating; Brain Neoplasms; Female; Humans; Longitudin

2018
Successful Novel Treatment of a Paraspinal Primitive Neuroectodermal Tumor with Predominantly Glial Differentiation: A 3-Year Follow-Up After Surgery, Intensity-Modulated Radiation Therapy and Oral Temozolomide.
    World neurosurgery, 2018, Volume: 119

    Topics: Administration, Oral; Antineoplastic Agents, Alkylating; Brain Neoplasms; Female; Humans; Longitudin

2018
Successful Novel Treatment of a Paraspinal Primitive Neuroectodermal Tumor with Predominantly Glial Differentiation: A 3-Year Follow-Up After Surgery, Intensity-Modulated Radiation Therapy and Oral Temozolomide.
    World neurosurgery, 2018, Volume: 119

    Topics: Administration, Oral; Antineoplastic Agents, Alkylating; Brain Neoplasms; Female; Humans; Longitudin

2018
Pyr3 Induces Apoptosis and Inhibits Migration in Human Glioblastoma Cells.
    Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 2018, Volume: 48, Issue:4

    Topics: Animals; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cell Movement; Cell Proliferation; Dacarbazin

2018
Pyr3 Induces Apoptosis and Inhibits Migration in Human Glioblastoma Cells.
    Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 2018, Volume: 48, Issue:4

    Topics: Animals; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cell Movement; Cell Proliferation; Dacarbazin

2018
Pyr3 Induces Apoptosis and Inhibits Migration in Human Glioblastoma Cells.
    Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 2018, Volume: 48, Issue:4

    Topics: Animals; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cell Movement; Cell Proliferation; Dacarbazin

2018
A Novel Tumor-Suppressor, CDH18, Inhibits Glioma Cell Invasiveness Via UQCRC2 and Correlates with the Prognosis of Glioma Patients.
    Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 2018, Volume: 48, Issue:4

    Topics: Aged; Animals; Biomarkers, Tumor; Brain Neoplasms; Cadherins; Cell Line, Tumor; Cell Movement; Cell

2018
A Novel Tumor-Suppressor, CDH18, Inhibits Glioma Cell Invasiveness Via UQCRC2 and Correlates with the Prognosis of Glioma Patients.
    Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 2018, Volume: 48, Issue:4

    Topics: Aged; Animals; Biomarkers, Tumor; Brain Neoplasms; Cadherins; Cell Line, Tumor; Cell Movement; Cell

2018
A Novel Tumor-Suppressor, CDH18, Inhibits Glioma Cell Invasiveness Via UQCRC2 and Correlates with the Prognosis of Glioma Patients.
    Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 2018, Volume: 48, Issue:4

    Topics: Aged; Animals; Biomarkers, Tumor; Brain Neoplasms; Cadherins; Cell Line, Tumor; Cell Movement; Cell

2018
Good tolerability of maintenance temozolomide in glioblastoma patients after severe hematological toxicity during concomitant radiotherapy and temozolomide treatment: report of two cases.
    Anti-cancer drugs, 2018, Volume: 29, Issue:9

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Female; Glioblastoma; Hematol

2018
Good tolerability of maintenance temozolomide in glioblastoma patients after severe hematological toxicity during concomitant radiotherapy and temozolomide treatment: report of two cases.
    Anti-cancer drugs, 2018, Volume: 29, Issue:9

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Female; Glioblastoma; Hematol

2018
Good tolerability of maintenance temozolomide in glioblastoma patients after severe hematological toxicity during concomitant radiotherapy and temozolomide treatment: report of two cases.
    Anti-cancer drugs, 2018, Volume: 29, Issue:9

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Female; Glioblastoma; Hematol

2018
Inhibition of autophagy increases susceptibility of glioblastoma stem cells to temozolomide by igniting ferroptosis.
    Cell death & disease, 2018, 08-06, Volume: 9, Issue:8

    Topics: Animals; Apoptosis; Autophagy; Brain Neoplasms; Cell Line, Tumor; Glioblastoma; Humans; Kaplan-Meier

2018
Inhibition of autophagy increases susceptibility of glioblastoma stem cells to temozolomide by igniting ferroptosis.
    Cell death & disease, 2018, 08-06, Volume: 9, Issue:8

    Topics: Animals; Apoptosis; Autophagy; Brain Neoplasms; Cell Line, Tumor; Glioblastoma; Humans; Kaplan-Meier

2018
Inhibition of autophagy increases susceptibility of glioblastoma stem cells to temozolomide by igniting ferroptosis.
    Cell death & disease, 2018, 08-06, Volume: 9, Issue:8

    Topics: Animals; Apoptosis; Autophagy; Brain Neoplasms; Cell Line, Tumor; Glioblastoma; Humans; Kaplan-Meier

2018
Exosomal transfer of miR-151a enhances chemosensitivity to temozolomide in drug-resistant glioblastoma.
    Cancer letters, 2018, 11-01, Volume: 436

    Topics: Adult; Animals; Antineoplastic Agents, Alkylating; Biomarkers, Tumor; Brain Neoplasms; Cell Line, Tu

2018
Exosomal transfer of miR-151a enhances chemosensitivity to temozolomide in drug-resistant glioblastoma.
    Cancer letters, 2018, 11-01, Volume: 436

    Topics: Adult; Animals; Antineoplastic Agents, Alkylating; Biomarkers, Tumor; Brain Neoplasms; Cell Line, Tu

2018
Exosomal transfer of miR-151a enhances chemosensitivity to temozolomide in drug-resistant glioblastoma.
    Cancer letters, 2018, 11-01, Volume: 436

    Topics: Adult; Animals; Antineoplastic Agents, Alkylating; Biomarkers, Tumor; Brain Neoplasms; Cell Line, Tu

2018
Incorporating diffusion- and perfusion-weighted MRI into a radiomics model improves diagnostic performance for pseudoprogression in glioblastoma patients.
    Neuro-oncology, 2019, 02-19, Volume: 21, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherap

2019
Incorporating diffusion- and perfusion-weighted MRI into a radiomics model improves diagnostic performance for pseudoprogression in glioblastoma patients.
    Neuro-oncology, 2019, 02-19, Volume: 21, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherap

2019
Incorporating diffusion- and perfusion-weighted MRI into a radiomics model improves diagnostic performance for pseudoprogression in glioblastoma patients.
    Neuro-oncology, 2019, 02-19, Volume: 21, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherap

2019
Bevacizumab therapy for recurrent gliomas: another disappointment?
    The Lancet. Oncology, 2018, Volume: 19, Issue:9

    Topics: Bevacizumab; Brain Neoplasms; Glioma; Humans; Neoplasm Recurrence, Local; Temozolomide

2018
Bevacizumab therapy for recurrent gliomas: another disappointment?
    The Lancet. Oncology, 2018, Volume: 19, Issue:9

    Topics: Bevacizumab; Brain Neoplasms; Glioma; Humans; Neoplasm Recurrence, Local; Temozolomide

2018
Bevacizumab therapy for recurrent gliomas: another disappointment?
    The Lancet. Oncology, 2018, Volume: 19, Issue:9

    Topics: Bevacizumab; Brain Neoplasms; Glioma; Humans; Neoplasm Recurrence, Local; Temozolomide

2018
CD73 Downregulation Decreases In Vitro and In Vivo Glioblastoma Growth.
    Molecular neurobiology, 2019, Volume: 56, Issue:5

    Topics: 5'-Nucleotidase; Adenosine; Animals; Biomarkers, Tumor; Brain Neoplasms; Cell Line, Tumor; Cell Move

2019
CD73 Downregulation Decreases In Vitro and In Vivo Glioblastoma Growth.
    Molecular neurobiology, 2019, Volume: 56, Issue:5

    Topics: 5'-Nucleotidase; Adenosine; Animals; Biomarkers, Tumor; Brain Neoplasms; Cell Line, Tumor; Cell Move

2019
CD73 Downregulation Decreases In Vitro and In Vivo Glioblastoma Growth.
    Molecular neurobiology, 2019, Volume: 56, Issue:5

    Topics: 5'-Nucleotidase; Adenosine; Animals; Biomarkers, Tumor; Brain Neoplasms; Cell Line, Tumor; Cell Move

2019
Combinations of four or more CpGs methylation present equivalent predictive value for MGMT expression and temozolomide therapeutic prognosis in gliomas.
    CNS neuroscience & therapeutics, 2019, Volume: 25, Issue:3

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Biomarkers, Tumor; Brain Neoplasms; Cohort Studies;

2019
Combinations of four or more CpGs methylation present equivalent predictive value for MGMT expression and temozolomide therapeutic prognosis in gliomas.
    CNS neuroscience & therapeutics, 2019, Volume: 25, Issue:3

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Biomarkers, Tumor; Brain Neoplasms; Cohort Studies;

2019
Combinations of four or more CpGs methylation present equivalent predictive value for MGMT expression and temozolomide therapeutic prognosis in gliomas.
    CNS neuroscience & therapeutics, 2019, Volume: 25, Issue:3

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Biomarkers, Tumor; Brain Neoplasms; Cohort Studies;

2019
MAPK8 mediates resistance to temozolomide and apoptosis of glioblastoma cells through MAPK signaling pathway.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2018, Volume: 106

    Topics: Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation;

2018
MAPK8 mediates resistance to temozolomide and apoptosis of glioblastoma cells through MAPK signaling pathway.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2018, Volume: 106

    Topics: Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation;

2018
MAPK8 mediates resistance to temozolomide and apoptosis of glioblastoma cells through MAPK signaling pathway.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2018, Volume: 106

    Topics: Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation;

2018
Bevacizumab, irinotecan, temozolomide, tyrosine kinase inhibition, and MEK inhibition are effective against pleomorphic xanthoastrocytoma regardless of V600E status.
    Journal of neuro-oncology, 2018, Volume: 140, Issue:2

    Topics: Animals; Antineoplastic Agents; Astrocytoma; Bevacizumab; Brain Neoplasms; Cell Line, Tumor; Female;

2018
Bevacizumab, irinotecan, temozolomide, tyrosine kinase inhibition, and MEK inhibition are effective against pleomorphic xanthoastrocytoma regardless of V600E status.
    Journal of neuro-oncology, 2018, Volume: 140, Issue:2

    Topics: Animals; Antineoplastic Agents; Astrocytoma; Bevacizumab; Brain Neoplasms; Cell Line, Tumor; Female;

2018
Bevacizumab, irinotecan, temozolomide, tyrosine kinase inhibition, and MEK inhibition are effective against pleomorphic xanthoastrocytoma regardless of V600E status.
    Journal of neuro-oncology, 2018, Volume: 140, Issue:2

    Topics: Animals; Antineoplastic Agents; Astrocytoma; Bevacizumab; Brain Neoplasms; Cell Line, Tumor; Female;

2018
Estimated lifetime survival benefit of tumor treating fields and temozolomide for newly diagnosed glioblastoma patients.
    CNS oncology, 2018, 07-01, Volume: 7, Issue:3

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Disease-Free Survival

2018
Estimated lifetime survival benefit of tumor treating fields and temozolomide for newly diagnosed glioblastoma patients.
    CNS oncology, 2018, 07-01, Volume: 7, Issue:3

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Disease-Free Survival

2018
Estimated lifetime survival benefit of tumor treating fields and temozolomide for newly diagnosed glioblastoma patients.
    CNS oncology, 2018, 07-01, Volume: 7, Issue:3

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Disease-Free Survival

2018
Optimization of a preclinical therapy of cannabinoids in combination with temozolomide against glioma.
    Biochemical pharmacology, 2018, Volume: 157

    Topics: Administration, Oral; Animals; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Cann

2018
Optimization of a preclinical therapy of cannabinoids in combination with temozolomide against glioma.
    Biochemical pharmacology, 2018, Volume: 157

    Topics: Administration, Oral; Animals; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Cann

2018
Optimization of a preclinical therapy of cannabinoids in combination with temozolomide against glioma.
    Biochemical pharmacology, 2018, Volume: 157

    Topics: Administration, Oral; Animals; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Cann

2018
Proapoptotic effects of novel thiazole derivative on human glioma cells.
    Anti-cancer drugs, 2019, Volume: 30, Issue:1

    Topics: Antineoplastic Agents; Apoptosis; Benzofurans; Brain Neoplasms; Cell Line, Tumor; DNA Damage; Doxoru

2019
Proapoptotic effects of novel thiazole derivative on human glioma cells.
    Anti-cancer drugs, 2019, Volume: 30, Issue:1

    Topics: Antineoplastic Agents; Apoptosis; Benzofurans; Brain Neoplasms; Cell Line, Tumor; DNA Damage; Doxoru

2019
Proapoptotic effects of novel thiazole derivative on human glioma cells.
    Anti-cancer drugs, 2019, Volume: 30, Issue:1

    Topics: Antineoplastic Agents; Apoptosis; Benzofurans; Brain Neoplasms; Cell Line, Tumor; DNA Damage; Doxoru

2019
Oxaliplatin disrupts pathological features of glioma cells and associated macrophages independent of apoptosis induction.
    Journal of neuro-oncology, 2018, Volume: 140, Issue:3

    Topics: Animals; Antineoplastic Agents; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Endoplasmic Reticulum

2018
Oxaliplatin disrupts pathological features of glioma cells and associated macrophages independent of apoptosis induction.
    Journal of neuro-oncology, 2018, Volume: 140, Issue:3

    Topics: Animals; Antineoplastic Agents; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Endoplasmic Reticulum

2018
Oxaliplatin disrupts pathological features of glioma cells and associated macrophages independent of apoptosis induction.
    Journal of neuro-oncology, 2018, Volume: 140, Issue:3

    Topics: Animals; Antineoplastic Agents; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Endoplasmic Reticulum

2018
MIM1, the Mcl-1 - specific BH3 mimetic induces apoptosis in human U87MG glioblastoma cells.
    Toxicology in vitro : an international journal published in association with BIBRA, 2018, Volume: 53

    Topics: Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cell Cycle; Cell Line, Tumor; Cell Su

2018
MIM1, the Mcl-1 - specific BH3 mimetic induces apoptosis in human U87MG glioblastoma cells.
    Toxicology in vitro : an international journal published in association with BIBRA, 2018, Volume: 53

    Topics: Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cell Cycle; Cell Line, Tumor; Cell Su

2018
MIM1, the Mcl-1 - specific BH3 mimetic induces apoptosis in human U87MG glioblastoma cells.
    Toxicology in vitro : an international journal published in association with BIBRA, 2018, Volume: 53

    Topics: Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cell Cycle; Cell Line, Tumor; Cell Su

2018
Adeno-associated virus 2 mediated gene transfer of vascular endothelial growth factor Trap: a new treatment option for glioma.
    Cancer biology & therapy, 2019, Volume: 20, Issue:1

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Brain Neoplasms; Cell Line, Tu

2019
Adeno-associated virus 2 mediated gene transfer of vascular endothelial growth factor Trap: a new treatment option for glioma.
    Cancer biology & therapy, 2019, Volume: 20, Issue:1

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Brain Neoplasms; Cell Line, Tu

2019
Adeno-associated virus 2 mediated gene transfer of vascular endothelial growth factor Trap: a new treatment option for glioma.
    Cancer biology & therapy, 2019, Volume: 20, Issue:1

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Brain Neoplasms; Cell Line, Tu

2019
Aspirin Affects Tumor Angiogenesis and Sensitizes Human Glioblastoma Endothelial Cells to Temozolomide, Bevacizumab, and Sunitinib, Impairing Vascular Endothelial Growth Factor-Related Signaling.
    World neurosurgery, 2018, Volume: 120

    Topics: Angiogenesis Inhibitors; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Antineoplas

2018
Aspirin Affects Tumor Angiogenesis and Sensitizes Human Glioblastoma Endothelial Cells to Temozolomide, Bevacizumab, and Sunitinib, Impairing Vascular Endothelial Growth Factor-Related Signaling.
    World neurosurgery, 2018, Volume: 120

    Topics: Angiogenesis Inhibitors; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Antineoplas

2018
Aspirin Affects Tumor Angiogenesis and Sensitizes Human Glioblastoma Endothelial Cells to Temozolomide, Bevacizumab, and Sunitinib, Impairing Vascular Endothelial Growth Factor-Related Signaling.
    World neurosurgery, 2018, Volume: 120

    Topics: Angiogenesis Inhibitors; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Antineoplas

2018
Dose-dense temozolomide for recurrent high-grade gliomas: a single-center retrospective study.
    Medical oncology (Northwood, London, England), 2018, Aug-28, Volume: 35, Issue:10

    Topics: Adult; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dose-Response Relationship, Drug; Female;

2018
Dose-dense temozolomide for recurrent high-grade gliomas: a single-center retrospective study.
    Medical oncology (Northwood, London, England), 2018, Aug-28, Volume: 35, Issue:10

    Topics: Adult; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dose-Response Relationship, Drug; Female;

2018
Dose-dense temozolomide for recurrent high-grade gliomas: a single-center retrospective study.
    Medical oncology (Northwood, London, England), 2018, Aug-28, Volume: 35, Issue:10

    Topics: Adult; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dose-Response Relationship, Drug; Female;

2018
FoxG1 facilitates proliferation and inhibits differentiation by downregulating FoxO/Smad signaling in glioblastoma.
    Biochemical and biophysical research communications, 2018, 09-26, Volume: 504, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Differentiation; Cell Line, Tumor; Cell Pro

2018
FoxG1 facilitates proliferation and inhibits differentiation by downregulating FoxO/Smad signaling in glioblastoma.
    Biochemical and biophysical research communications, 2018, 09-26, Volume: 504, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Differentiation; Cell Line, Tumor; Cell Pro

2018
FoxG1 facilitates proliferation and inhibits differentiation by downregulating FoxO/Smad signaling in glioblastoma.
    Biochemical and biophysical research communications, 2018, 09-26, Volume: 504, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Differentiation; Cell Line, Tumor; Cell Pro

2018
Nose-to-brain delivery of temozolomide-loaded PLGA nanoparticles functionalized with anti-EPHA3 for glioblastoma targeting.
    Drug delivery, 2018, Volume: 25, Issue:1

    Topics: Animals; Antibodies, Monoclonal; Antineoplastic Agents; Brain Neoplasms; Cell Line, Tumor; Drug Carr

2018
Nose-to-brain delivery of temozolomide-loaded PLGA nanoparticles functionalized with anti-EPHA3 for glioblastoma targeting.
    Drug delivery, 2018, Volume: 25, Issue:1

    Topics: Animals; Antibodies, Monoclonal; Antineoplastic Agents; Brain Neoplasms; Cell Line, Tumor; Drug Carr

2018
Nose-to-brain delivery of temozolomide-loaded PLGA nanoparticles functionalized with anti-EPHA3 for glioblastoma targeting.
    Drug delivery, 2018, Volume: 25, Issue:1

    Topics: Animals; Antibodies, Monoclonal; Antineoplastic Agents; Brain Neoplasms; Cell Line, Tumor; Drug Carr

2018
Cell Subpopulations Overexpressing p75NTR Have Tumor-initiating Properties in the C6 Glioma Cell Line.
    Anticancer research, 2018, Volume: 38, Issue:9

    Topics: Animals; Biomarkers, Tumor; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Cell Survival; Da

2018
Cell Subpopulations Overexpressing p75NTR Have Tumor-initiating Properties in the C6 Glioma Cell Line.
    Anticancer research, 2018, Volume: 38, Issue:9

    Topics: Animals; Biomarkers, Tumor; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Cell Survival; Da

2018
Cell Subpopulations Overexpressing p75NTR Have Tumor-initiating Properties in the C6 Glioma Cell Line.
    Anticancer research, 2018, Volume: 38, Issue:9

    Topics: Animals; Biomarkers, Tumor; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Cell Survival; Da

2018
Targeting Glioma Initiating Cells with A combined therapy of cannabinoids and temozolomide.
    Biochemical pharmacology, 2018, Volume: 157

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Cannabidiol; Cell Line, Tu

2018
Targeting Glioma Initiating Cells with A combined therapy of cannabinoids and temozolomide.
    Biochemical pharmacology, 2018, Volume: 157

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Cannabidiol; Cell Line, Tu

2018
Targeting Glioma Initiating Cells with A combined therapy of cannabinoids and temozolomide.
    Biochemical pharmacology, 2018, Volume: 157

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Cannabidiol; Cell Line, Tu

2018
Achievable Central Nervous System Concentrations of the Green Tea Catechin EGCG Induce Stress in Glioblastoma Cells in Vitro.
    Nutrition and cancer, 2018, Volume: 70, Issue:7

    Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Autophagy; Brain Neoplasms; Catechin; Cen

2018
Achievable Central Nervous System Concentrations of the Green Tea Catechin EGCG Induce Stress in Glioblastoma Cells in Vitro.
    Nutrition and cancer, 2018, Volume: 70, Issue:7

    Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Autophagy; Brain Neoplasms; Catechin; Cen

2018
Achievable Central Nervous System Concentrations of the Green Tea Catechin EGCG Induce Stress in Glioblastoma Cells in Vitro.
    Nutrition and cancer, 2018, Volume: 70, Issue:7

    Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Autophagy; Brain Neoplasms; Catechin; Cen

2018
A tension-mediated glycocalyx-integrin feedback loop promotes mesenchymal-like glioblastoma.
    Nature cell biology, 2018, Volume: 20, Issue:10

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Survival; Feedback, Physiological;

2018
A tension-mediated glycocalyx-integrin feedback loop promotes mesenchymal-like glioblastoma.
    Nature cell biology, 2018, Volume: 20, Issue:10

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Survival; Feedback, Physiological;

2018
A tension-mediated glycocalyx-integrin feedback loop promotes mesenchymal-like glioblastoma.
    Nature cell biology, 2018, Volume: 20, Issue:10

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Survival; Feedback, Physiological;

2018
SOX3 can promote the malignant behavior of glioblastoma cells.
    Cellular oncology (Dordrecht), 2019, Volume: 42, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Autophagy; Brain Neoplasms; Cell Line, Tumor; Cell Movement; Cell Pr

2019
SOX3 can promote the malignant behavior of glioblastoma cells.
    Cellular oncology (Dordrecht), 2019, Volume: 42, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Autophagy; Brain Neoplasms; Cell Line, Tumor; Cell Movement; Cell Pr

2019
SOX3 can promote the malignant behavior of glioblastoma cells.
    Cellular oncology (Dordrecht), 2019, Volume: 42, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Autophagy; Brain Neoplasms; Cell Line, Tumor; Cell Movement; Cell Pr

2019
FOXO1 associated with sensitivity to chemotherapy drugs and glial-mesenchymal transition in glioma.
    Journal of cellular biochemistry, 2019, Volume: 120, Issue:1

    Topics: Animals; Antineoplastic Agents, Alkylating; Biomarkers, Tumor; Brain Neoplasms; Carmustine; Cell Adh

2019
FOXO1 associated with sensitivity to chemotherapy drugs and glial-mesenchymal transition in glioma.
    Journal of cellular biochemistry, 2019, Volume: 120, Issue:1

    Topics: Animals; Antineoplastic Agents, Alkylating; Biomarkers, Tumor; Brain Neoplasms; Carmustine; Cell Adh

2019
FOXO1 associated with sensitivity to chemotherapy drugs and glial-mesenchymal transition in glioma.
    Journal of cellular biochemistry, 2019, Volume: 120, Issue:1

    Topics: Animals; Antineoplastic Agents, Alkylating; Biomarkers, Tumor; Brain Neoplasms; Carmustine; Cell Adh

2019
PDZ-RhoGEF Is a Signaling Effector for TROY-Induced Glioblastoma Cell Invasion and Survival.
    Neoplasia (New York, N.Y.), 2018, Volume: 20, Issue:10

    Topics: Animals; Brain Neoplasms; Cell Line, Tumor; Cell Survival; Female; Focal Adhesion Kinase 2; Gene Exp

2018
PDZ-RhoGEF Is a Signaling Effector for TROY-Induced Glioblastoma Cell Invasion and Survival.
    Neoplasia (New York, N.Y.), 2018, Volume: 20, Issue:10

    Topics: Animals; Brain Neoplasms; Cell Line, Tumor; Cell Survival; Female; Focal Adhesion Kinase 2; Gene Exp

2018
PDZ-RhoGEF Is a Signaling Effector for TROY-Induced Glioblastoma Cell Invasion and Survival.
    Neoplasia (New York, N.Y.), 2018, Volume: 20, Issue:10

    Topics: Animals; Brain Neoplasms; Cell Line, Tumor; Cell Survival; Female; Focal Adhesion Kinase 2; Gene Exp

2018
Whole-Genome Multi-omic Study of Survival in Patients with Glioblastoma Multiforme.
    G3 (Bethesda, Md.), 2018, 11-06, Volume: 8, Issue:11

    Topics: Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; DNA Copy Number Variations; DNA Methylatio

2018
Whole-Genome Multi-omic Study of Survival in Patients with Glioblastoma Multiforme.
    G3 (Bethesda, Md.), 2018, 11-06, Volume: 8, Issue:11

    Topics: Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; DNA Copy Number Variations; DNA Methylatio

2018
Whole-Genome Multi-omic Study of Survival in Patients with Glioblastoma Multiforme.
    G3 (Bethesda, Md.), 2018, 11-06, Volume: 8, Issue:11

    Topics: Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; DNA Copy Number Variations; DNA Methylatio

2018
Validation of a novel molecular RPA classification in glioblastoma (GBM-molRPA) treated with chemoradiation: A multi-institutional collaborative study.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2018, Volume: 129, Issue:2

    Topics: Adult; Aged; Brain Neoplasms; Chemoradiotherapy; DNA Methylation; DNA Modification Methylases; DNA R

2018
Validation of a novel molecular RPA classification in glioblastoma (GBM-molRPA) treated with chemoradiation: A multi-institutional collaborative study.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2018, Volume: 129, Issue:2

    Topics: Adult; Aged; Brain Neoplasms; Chemoradiotherapy; DNA Methylation; DNA Modification Methylases; DNA R

2018
Validation of a novel molecular RPA classification in glioblastoma (GBM-molRPA) treated with chemoradiation: A multi-institutional collaborative study.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2018, Volume: 129, Issue:2

    Topics: Adult; Aged; Brain Neoplasms; Chemoradiotherapy; DNA Methylation; DNA Modification Methylases; DNA R

2018
Development and validation of simple step protein precipitation UHPLC-MS/MS methods for quantitation of temozolomide in cancer patient plasma samples.
    Journal of pharmaceutical and biomedical analysis, 2019, Jan-05, Volume: 162

    Topics: Administration, Oral; Antineoplastic Agents, Alkylating; Brain Neoplasms; Calibration; Chemical Prec

2019
Development and validation of simple step protein precipitation UHPLC-MS/MS methods for quantitation of temozolomide in cancer patient plasma samples.
    Journal of pharmaceutical and biomedical analysis, 2019, Jan-05, Volume: 162

    Topics: Administration, Oral; Antineoplastic Agents, Alkylating; Brain Neoplasms; Calibration; Chemical Prec

2019
Development and validation of simple step protein precipitation UHPLC-MS/MS methods for quantitation of temozolomide in cancer patient plasma samples.
    Journal of pharmaceutical and biomedical analysis, 2019, Jan-05, Volume: 162

    Topics: Administration, Oral; Antineoplastic Agents, Alkylating; Brain Neoplasms; Calibration; Chemical Prec

2019
Diagnostic utility of restriction spectrum imaging (RSI) in glioblastoma patients after concurrent radiation-temozolomide treatment: A pilot study.
    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2018, Volume: 58

    Topics: Adult; Aged; Biopsy; Brain Neoplasms; Chemoradiotherapy; Diffusion Magnetic Resonance Imaging; Femal

2018
Diagnostic utility of restriction spectrum imaging (RSI) in glioblastoma patients after concurrent radiation-temozolomide treatment: A pilot study.
    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2018, Volume: 58

    Topics: Adult; Aged; Biopsy; Brain Neoplasms; Chemoradiotherapy; Diffusion Magnetic Resonance Imaging; Femal

2018
Diagnostic utility of restriction spectrum imaging (RSI) in glioblastoma patients after concurrent radiation-temozolomide treatment: A pilot study.
    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2018, Volume: 58

    Topics: Adult; Aged; Biopsy; Brain Neoplasms; Chemoradiotherapy; Diffusion Magnetic Resonance Imaging; Femal

2018
Carbonic Anhydrase XII Inhibitors Overcome P-Glycoprotein-Mediated Resistance to Temozolomide in Glioblastoma.
    Molecular cancer therapeutics, 2018, Volume: 17, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Brain Neoplasms; Carbonic Anhydras

2018
Carbonic Anhydrase XII Inhibitors Overcome P-Glycoprotein-Mediated Resistance to Temozolomide in Glioblastoma.
    Molecular cancer therapeutics, 2018, Volume: 17, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Brain Neoplasms; Carbonic Anhydras

2018
Carbonic Anhydrase XII Inhibitors Overcome P-Glycoprotein-Mediated Resistance to Temozolomide in Glioblastoma.
    Molecular cancer therapeutics, 2018, Volume: 17, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Brain Neoplasms; Carbonic Anhydras

2018
Polyethylenimine-Spherical Nucleic Acid Nanoparticles against Gli1 Reduce the Chemoresistance and Stemness of Glioblastoma Cells.
    Molecular pharmaceutics, 2018, 11-05, Volume: 15, Issue:11

    Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Drug C

2018
Polyethylenimine-Spherical Nucleic Acid Nanoparticles against Gli1 Reduce the Chemoresistance and Stemness of Glioblastoma Cells.
    Molecular pharmaceutics, 2018, 11-05, Volume: 15, Issue:11

    Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Drug C

2018
Polyethylenimine-Spherical Nucleic Acid Nanoparticles against Gli1 Reduce the Chemoresistance and Stemness of Glioblastoma Cells.
    Molecular pharmaceutics, 2018, 11-05, Volume: 15, Issue:11

    Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Drug C

2018
Juniperus Communis Extract Exerts Antitumor Effects in Human Glioblastomas Through Blood-Brain Barrier.
    Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 2018, Volume: 49, Issue:6

    Topics: Animals; Apoptosis; Blood-Brain Barrier; Brain Neoplasms; Caspase 3; Cell Cycle Checkpoints; Cell Li

2018
Juniperus Communis Extract Exerts Antitumor Effects in Human Glioblastomas Through Blood-Brain Barrier.
    Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 2018, Volume: 49, Issue:6

    Topics: Animals; Apoptosis; Blood-Brain Barrier; Brain Neoplasms; Caspase 3; Cell Cycle Checkpoints; Cell Li

2018
Juniperus Communis Extract Exerts Antitumor Effects in Human Glioblastomas Through Blood-Brain Barrier.
    Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 2018, Volume: 49, Issue:6

    Topics: Animals; Apoptosis; Blood-Brain Barrier; Brain Neoplasms; Caspase 3; Cell Cycle Checkpoints; Cell Li

2018
Feasibility and robustness of dynamic
    Scientific reports, 2018, 10-03, Volume: 8, Issue:1

    Topics: Aged; Antineoplastic Agents; Brain Neoplasms; Carbon; Female; Glioma; Heavy Ion Radiotherapy; Humans

2018
Feasibility and robustness of dynamic
    Scientific reports, 2018, 10-03, Volume: 8, Issue:1

    Topics: Aged; Antineoplastic Agents; Brain Neoplasms; Carbon; Female; Glioma; Heavy Ion Radiotherapy; Humans

2018
Feasibility and robustness of dynamic
    Scientific reports, 2018, 10-03, Volume: 8, Issue:1

    Topics: Aged; Antineoplastic Agents; Brain Neoplasms; Carbon; Female; Glioma; Heavy Ion Radiotherapy; Humans

2018
Radiotherapy plus temozolomide or PCV in patients with anaplastic oligodendroglioma 1p19q codeleted.
    Revista de neurologia, 2018, Oct-16, Volume: 67, Issue:8

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Brai

2018
Radiotherapy plus temozolomide or PCV in patients with anaplastic oligodendroglioma 1p19q codeleted.
    Revista de neurologia, 2018, Oct-16, Volume: 67, Issue:8

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Brai

2018
Radiotherapy plus temozolomide or PCV in patients with anaplastic oligodendroglioma 1p19q codeleted.
    Revista de neurologia, 2018, Oct-16, Volume: 67, Issue:8

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Brai

2018
Thioridazine inhibits autophagy and sensitizes glioblastoma cells to temozolomide.
    International journal of cancer, 2019, 04-01, Volume: 144, Issue:7

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Autophagosomes; Autophagy; Brain Neoplasms;

2019
Thioridazine inhibits autophagy and sensitizes glioblastoma cells to temozolomide.
    International journal of cancer, 2019, 04-01, Volume: 144, Issue:7

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Autophagosomes; Autophagy; Brain Neoplasms;

2019
Thioridazine inhibits autophagy and sensitizes glioblastoma cells to temozolomide.
    International journal of cancer, 2019, 04-01, Volume: 144, Issue:7

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Autophagosomes; Autophagy; Brain Neoplasms;

2019
Resveratrol restores sensitivity of glioma cells to temozolamide through inhibiting the activation of Wnt signaling pathway.
    Journal of cellular physiology, 2019, Volume: 234, Issue:5

    Topics: Animals; Apoptosis; Brain Neoplasms; Cell Line; Cell Line, Tumor; Cell Proliferation; Cell Survival;

2019
Resveratrol restores sensitivity of glioma cells to temozolamide through inhibiting the activation of Wnt signaling pathway.
    Journal of cellular physiology, 2019, Volume: 234, Issue:5

    Topics: Animals; Apoptosis; Brain Neoplasms; Cell Line; Cell Line, Tumor; Cell Proliferation; Cell Survival;

2019
Resveratrol restores sensitivity of glioma cells to temozolamide through inhibiting the activation of Wnt signaling pathway.
    Journal of cellular physiology, 2019, Volume: 234, Issue:5

    Topics: Animals; Apoptosis; Brain Neoplasms; Cell Line; Cell Line, Tumor; Cell Proliferation; Cell Survival;

2019
Cordycepin Augments the Chemosensitivity of Human Glioma Cells to Temozolomide by Activating AMPK and Inhibiting the AKT Signaling Pathway.
    Molecular pharmaceutics, 2018, 11-05, Volume: 15, Issue:11

    Topics: AMP-Activated Protein Kinases; Animals; Antineoplastic Combined Chemotherapy Protocols; Brain Neopla

2018
Cordycepin Augments the Chemosensitivity of Human Glioma Cells to Temozolomide by Activating AMPK and Inhibiting the AKT Signaling Pathway.
    Molecular pharmaceutics, 2018, 11-05, Volume: 15, Issue:11

    Topics: AMP-Activated Protein Kinases; Animals; Antineoplastic Combined Chemotherapy Protocols; Brain Neopla

2018
Cordycepin Augments the Chemosensitivity of Human Glioma Cells to Temozolomide by Activating AMPK and Inhibiting the AKT Signaling Pathway.
    Molecular pharmaceutics, 2018, 11-05, Volume: 15, Issue:11

    Topics: AMP-Activated Protein Kinases; Animals; Antineoplastic Combined Chemotherapy Protocols; Brain Neopla

2018
Polymer-Temozolomide Conjugates as Therapeutics for Treating Glioblastoma.
    Molecular pharmaceutics, 2018, 11-05, Volume: 15, Issue:11

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Drug Carriers; Drug Compoundin

2018
Polymer-Temozolomide Conjugates as Therapeutics for Treating Glioblastoma.
    Molecular pharmaceutics, 2018, 11-05, Volume: 15, Issue:11

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Drug Carriers; Drug Compoundin

2018
Polymer-Temozolomide Conjugates as Therapeutics for Treating Glioblastoma.
    Molecular pharmaceutics, 2018, 11-05, Volume: 15, Issue:11

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Drug Carriers; Drug Compoundin

2018
Plasma and brain pharmacokinetics of letrozole and drug interaction studies with temozolomide in NOD-scid gamma mice and sprague dawley rats.
    Cancer chemotherapy and pharmacology, 2019, Volume: 83, Issue:1

    Topics: Animals; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Brain; Brain Neoplasms; Drug Inte

2019
Plasma and brain pharmacokinetics of letrozole and drug interaction studies with temozolomide in NOD-scid gamma mice and sprague dawley rats.
    Cancer chemotherapy and pharmacology, 2019, Volume: 83, Issue:1

    Topics: Animals; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Brain; Brain Neoplasms; Drug Inte

2019
Plasma and brain pharmacokinetics of letrozole and drug interaction studies with temozolomide in NOD-scid gamma mice and sprague dawley rats.
    Cancer chemotherapy and pharmacology, 2019, Volume: 83, Issue:1

    Topics: Animals; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Brain; Brain Neoplasms; Drug Inte

2019
Loss of programmed cell death 10 activates tumor cells and leads to temozolomide-resistance in glioblastoma.
    Journal of neuro-oncology, 2019, Volume: 141, Issue:1

    Topics: Animals; Antineoplastic Agents, Alkylating; Apoptosis; Apoptosis Regulatory Proteins; Brain Neoplasm

2019
Loss of programmed cell death 10 activates tumor cells and leads to temozolomide-resistance in glioblastoma.
    Journal of neuro-oncology, 2019, Volume: 141, Issue:1

    Topics: Animals; Antineoplastic Agents, Alkylating; Apoptosis; Apoptosis Regulatory Proteins; Brain Neoplasm

2019
Loss of programmed cell death 10 activates tumor cells and leads to temozolomide-resistance in glioblastoma.
    Journal of neuro-oncology, 2019, Volume: 141, Issue:1

    Topics: Animals; Antineoplastic Agents, Alkylating; Apoptosis; Apoptosis Regulatory Proteins; Brain Neoplasm

2019
Studies examining the synergy between Dihydrotanshinone and Temozolomide against MGMT+ glioblastoma cells in vitro: Predicting interactions with the blood-brain barrier.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2019, Volume: 109

    Topics: Abietanes; Antineoplastic Agents, Alkylating; Blood-Brain Barrier; Brain Neoplasms; Cell Line, Tumor

2019
Studies examining the synergy between Dihydrotanshinone and Temozolomide against MGMT+ glioblastoma cells in vitro: Predicting interactions with the blood-brain barrier.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2019, Volume: 109

    Topics: Abietanes; Antineoplastic Agents, Alkylating; Blood-Brain Barrier; Brain Neoplasms; Cell Line, Tumor

2019
Studies examining the synergy between Dihydrotanshinone and Temozolomide against MGMT+ glioblastoma cells in vitro: Predicting interactions with the blood-brain barrier.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2019, Volume: 109

    Topics: Abietanes; Antineoplastic Agents, Alkylating; Blood-Brain Barrier; Brain Neoplasms; Cell Line, Tumor

2019
A Novel Venom-Derived Peptide for Brachytherapy of Glioblastoma: Preclinical Studies in Mice.
    Molecules (Basel, Switzerland), 2018, Nov-08, Volume: 23, Issue:11

    Topics: Animals; Brachytherapy; Brain Neoplasms; Cell Proliferation; Cell Survival; Disintegrins; Drug Syner

2018
A Novel Venom-Derived Peptide for Brachytherapy of Glioblastoma: Preclinical Studies in Mice.
    Molecules (Basel, Switzerland), 2018, Nov-08, Volume: 23, Issue:11

    Topics: Animals; Brachytherapy; Brain Neoplasms; Cell Proliferation; Cell Survival; Disintegrins; Drug Syner

2018
A Novel Venom-Derived Peptide for Brachytherapy of Glioblastoma: Preclinical Studies in Mice.
    Molecules (Basel, Switzerland), 2018, Nov-08, Volume: 23, Issue:11

    Topics: Animals; Brachytherapy; Brain Neoplasms; Cell Proliferation; Cell Survival; Disintegrins; Drug Syner

2018
Podoplanin expression is a prognostic biomarker but may be dispensable for the malignancy of glioblastoma.
    Neuro-oncology, 2019, 02-19, Volume: 21, Issue:3

    Topics: Animals; Antineoplastic Agents, Alkylating; Apoptosis; Brain; Brain Neoplasms; Cell Line, Tumor; Cel

2019
Podoplanin expression is a prognostic biomarker but may be dispensable for the malignancy of glioblastoma.
    Neuro-oncology, 2019, 02-19, Volume: 21, Issue:3

    Topics: Animals; Antineoplastic Agents, Alkylating; Apoptosis; Brain; Brain Neoplasms; Cell Line, Tumor; Cel

2019
Podoplanin expression is a prognostic biomarker but may be dispensable for the malignancy of glioblastoma.
    Neuro-oncology, 2019, 02-19, Volume: 21, Issue:3

    Topics: Animals; Antineoplastic Agents, Alkylating; Apoptosis; Brain; Brain Neoplasms; Cell Line, Tumor; Cel

2019
Knockdown of BCL6 Inhibited Malignant Phenotype and Enhanced Sensitivity of Glioblastoma Cells to TMZ through AKT Pathway.
    BioMed research international, 2018, Volume: 2018

    Topics: Antineoplastic Agents; Brain; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Drug Resistance

2018
Knockdown of BCL6 Inhibited Malignant Phenotype and Enhanced Sensitivity of Glioblastoma Cells to TMZ through AKT Pathway.
    BioMed research international, 2018, Volume: 2018

    Topics: Antineoplastic Agents; Brain; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Drug Resistance

2018
Knockdown of BCL6 Inhibited Malignant Phenotype and Enhanced Sensitivity of Glioblastoma Cells to TMZ through AKT Pathway.
    BioMed research international, 2018, Volume: 2018

    Topics: Antineoplastic Agents; Brain; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Drug Resistance

2018
Hypoxia-mediated mitochondria apoptosis inhibition induces temozolomide treatment resistance through miR-26a/Bad/Bax axis.
    Cell death & disease, 2018, 11-13, Volume: 9, Issue:11

    Topics: Animals; Antagomirs; Antineoplastic Agents, Alkylating; Apoptosis; bcl-2-Associated X Protein; bcl-A

2018
Hypoxia-mediated mitochondria apoptosis inhibition induces temozolomide treatment resistance through miR-26a/Bad/Bax axis.
    Cell death & disease, 2018, 11-13, Volume: 9, Issue:11

    Topics: Animals; Antagomirs; Antineoplastic Agents, Alkylating; Apoptosis; bcl-2-Associated X Protein; bcl-A

2018
Hypoxia-mediated mitochondria apoptosis inhibition induces temozolomide treatment resistance through miR-26a/Bad/Bax axis.
    Cell death & disease, 2018, 11-13, Volume: 9, Issue:11

    Topics: Animals; Antagomirs; Antineoplastic Agents, Alkylating; Apoptosis; bcl-2-Associated X Protein; bcl-A

2018
Functional analysis of protein disulfide isomerase P5 in glioblastoma cells as a novel anticancer target.
    Oncology reports, 2019, Volume: 41, Issue:2

    Topics: Anacardic Acids; Antineoplastic Agents; Brain Neoplasms; Cell Line, Tumor; Cell Membrane; Drug Scree

2019
Functional analysis of protein disulfide isomerase P5 in glioblastoma cells as a novel anticancer target.
    Oncology reports, 2019, Volume: 41, Issue:2

    Topics: Anacardic Acids; Antineoplastic Agents; Brain Neoplasms; Cell Line, Tumor; Cell Membrane; Drug Scree

2019
Functional analysis of protein disulfide isomerase P5 in glioblastoma cells as a novel anticancer target.
    Oncology reports, 2019, Volume: 41, Issue:2

    Topics: Anacardic Acids; Antineoplastic Agents; Brain Neoplasms; Cell Line, Tumor; Cell Membrane; Drug Scree

2019
20(S)-ginsenoside-Rg3 reverses temozolomide resistance and restrains epithelial-mesenchymal transition progression in glioblastoma.
    Cancer science, 2019, Volume: 110, Issue:1

    Topics: Animals; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Phytogenic; Brain Neoplasms; Cell

2019
20(S)-ginsenoside-Rg3 reverses temozolomide resistance and restrains epithelial-mesenchymal transition progression in glioblastoma.
    Cancer science, 2019, Volume: 110, Issue:1

    Topics: Animals; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Phytogenic; Brain Neoplasms; Cell

2019
20(S)-ginsenoside-Rg3 reverses temozolomide resistance and restrains epithelial-mesenchymal transition progression in glioblastoma.
    Cancer science, 2019, Volume: 110, Issue:1

    Topics: Animals; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Phytogenic; Brain Neoplasms; Cell

2019
Tumour volume reduction following PET guided intensity modulated radiation therapy and temozolomide in IDH mutated anaplastic glioma.
    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2019, Volume: 59

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Female; Humans;

2019
Tumour volume reduction following PET guided intensity modulated radiation therapy and temozolomide in IDH mutated anaplastic glioma.
    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2019, Volume: 59

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Female; Humans;

2019
Tumour volume reduction following PET guided intensity modulated radiation therapy and temozolomide in IDH mutated anaplastic glioma.
    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2019, Volume: 59

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Female; Humans;

2019
Down-regulation of ABCE1 inhibits temozolomide resistance in glioma through the PI3K/Akt/NF-κB signaling pathway.
    Bioscience reports, 2018, 12-21, Volume: 38, Issue:6

    Topics: Animals; Antineoplastic Agents, Alkylating; ATP-Binding Cassette Transporters; Brain Neoplasms; Cell

2018
Down-regulation of ABCE1 inhibits temozolomide resistance in glioma through the PI3K/Akt/NF-κB signaling pathway.
    Bioscience reports, 2018, 12-21, Volume: 38, Issue:6

    Topics: Animals; Antineoplastic Agents, Alkylating; ATP-Binding Cassette Transporters; Brain Neoplasms; Cell

2018
Down-regulation of ABCE1 inhibits temozolomide resistance in glioma through the PI3K/Akt/NF-κB signaling pathway.
    Bioscience reports, 2018, 12-21, Volume: 38, Issue:6

    Topics: Animals; Antineoplastic Agents, Alkylating; ATP-Binding Cassette Transporters; Brain Neoplasms; Cell

2018
Carnosic acid potentiates the anticancer effect of temozolomide by inducing apoptosis and autophagy in glioma.
    Journal of neuro-oncology, 2019, Volume: 141, Issue:2

    Topics: Abietanes; Antineoplastic Agents, Alkylating; Apoptosis; Autophagy; Brain Neoplasms; Cell Cycle Chec

2019
Carnosic acid potentiates the anticancer effect of temozolomide by inducing apoptosis and autophagy in glioma.
    Journal of neuro-oncology, 2019, Volume: 141, Issue:2

    Topics: Abietanes; Antineoplastic Agents, Alkylating; Apoptosis; Autophagy; Brain Neoplasms; Cell Cycle Chec

2019
Carnosic acid potentiates the anticancer effect of temozolomide by inducing apoptosis and autophagy in glioma.
    Journal of neuro-oncology, 2019, Volume: 141, Issue:2

    Topics: Abietanes; Antineoplastic Agents, Alkylating; Apoptosis; Autophagy; Brain Neoplasms; Cell Cycle Chec

2019
Increase of pseudoprogression and other treatment related effects in low-grade glioma patients treated with proton radiation and temozolomide.
    Journal of neuro-oncology, 2019, Volume: 142, Issue:1

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Thera

2019
Increase of pseudoprogression and other treatment related effects in low-grade glioma patients treated with proton radiation and temozolomide.
    Journal of neuro-oncology, 2019, Volume: 142, Issue:1

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Thera

2019
Increase of pseudoprogression and other treatment related effects in low-grade glioma patients treated with proton radiation and temozolomide.
    Journal of neuro-oncology, 2019, Volume: 142, Issue:1

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Thera

2019
Increased compliance with tumor treating fields therapy is prognostic for improved survival in the treatment of glioblastoma: a subgroup analysis of the EF-14 phase III trial.
    Journal of neuro-oncology, 2019, Volume: 141, Issue:2

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Clinical Trials, Phase III as Topic

2019
Increased compliance with tumor treating fields therapy is prognostic for improved survival in the treatment of glioblastoma: a subgroup analysis of the EF-14 phase III trial.
    Journal of neuro-oncology, 2019, Volume: 141, Issue:2

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Clinical Trials, Phase III as Topic

2019
Increased compliance with tumor treating fields therapy is prognostic for improved survival in the treatment of glioblastoma: a subgroup analysis of the EF-14 phase III trial.
    Journal of neuro-oncology, 2019, Volume: 141, Issue:2

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Clinical Trials, Phase III as Topic

2019
Increased compliance with tumor treating fields therapy is prognostic for improved survival in the treatment of glioblastoma: a subgroup analysis of the EF-14 phase III trial.
    Journal of neuro-oncology, 2019, Volume: 141, Issue:2

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Clinical Trials, Phase III as Topic

2019
Increased compliance with tumor treating fields therapy is prognostic for improved survival in the treatment of glioblastoma: a subgroup analysis of the EF-14 phase III trial.
    Journal of neuro-oncology, 2019, Volume: 141, Issue:2

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Clinical Trials, Phase III as Topic

2019
Increased compliance with tumor treating fields therapy is prognostic for improved survival in the treatment of glioblastoma: a subgroup analysis of the EF-14 phase III trial.
    Journal of neuro-oncology, 2019, Volume: 141, Issue:2

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Clinical Trials, Phase III as Topic

2019
Increased compliance with tumor treating fields therapy is prognostic for improved survival in the treatment of glioblastoma: a subgroup analysis of the EF-14 phase III trial.
    Journal of neuro-oncology, 2019, Volume: 141, Issue:2

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Clinical Trials, Phase III as Topic

2019
Increased compliance with tumor treating fields therapy is prognostic for improved survival in the treatment of glioblastoma: a subgroup analysis of the EF-14 phase III trial.
    Journal of neuro-oncology, 2019, Volume: 141, Issue:2

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Clinical Trials, Phase III as Topic

2019
Increased compliance with tumor treating fields therapy is prognostic for improved survival in the treatment of glioblastoma: a subgroup analysis of the EF-14 phase III trial.
    Journal of neuro-oncology, 2019, Volume: 141, Issue:2

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Clinical Trials, Phase III as Topic

2019
Increased compliance with tumor treating fields therapy is prognostic for improved survival in the treatment of glioblastoma: a subgroup analysis of the EF-14 phase III trial.
    Journal of neuro-oncology, 2019, Volume: 141, Issue:2

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Clinical Trials, Phase III as Topic

2019
Increased compliance with tumor treating fields therapy is prognostic for improved survival in the treatment of glioblastoma: a subgroup analysis of the EF-14 phase III trial.
    Journal of neuro-oncology, 2019, Volume: 141, Issue:2

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Clinical Trials, Phase III as Topic

2019
Increased compliance with tumor treating fields therapy is prognostic for improved survival in the treatment of glioblastoma: a subgroup analysis of the EF-14 phase III trial.
    Journal of neuro-oncology, 2019, Volume: 141, Issue:2

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Clinical Trials, Phase III as Topic

2019
Increased compliance with tumor treating fields therapy is prognostic for improved survival in the treatment of glioblastoma: a subgroup analysis of the EF-14 phase III trial.
    Journal of neuro-oncology, 2019, Volume: 141, Issue:2

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Clinical Trials, Phase III as Topic

2019
Increased compliance with tumor treating fields therapy is prognostic for improved survival in the treatment of glioblastoma: a subgroup analysis of the EF-14 phase III trial.
    Journal of neuro-oncology, 2019, Volume: 141, Issue:2

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Clinical Trials, Phase III as Topic

2019
Increased compliance with tumor treating fields therapy is prognostic for improved survival in the treatment of glioblastoma: a subgroup analysis of the EF-14 phase III trial.
    Journal of neuro-oncology, 2019, Volume: 141, Issue:2

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Clinical Trials, Phase III as Topic

2019
Increased compliance with tumor treating fields therapy is prognostic for improved survival in the treatment of glioblastoma: a subgroup analysis of the EF-14 phase III trial.
    Journal of neuro-oncology, 2019, Volume: 141, Issue:2

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Clinical Trials, Phase III as Topic

2019
Increased compliance with tumor treating fields therapy is prognostic for improved survival in the treatment of glioblastoma: a subgroup analysis of the EF-14 phase III trial.
    Journal of neuro-oncology, 2019, Volume: 141, Issue:2

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Clinical Trials, Phase III as Topic

2019
Increased compliance with tumor treating fields therapy is prognostic for improved survival in the treatment of glioblastoma: a subgroup analysis of the EF-14 phase III trial.
    Journal of neuro-oncology, 2019, Volume: 141, Issue:2

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Clinical Trials, Phase III as Topic

2019
Increased compliance with tumor treating fields therapy is prognostic for improved survival in the treatment of glioblastoma: a subgroup analysis of the EF-14 phase III trial.
    Journal of neuro-oncology, 2019, Volume: 141, Issue:2

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Clinical Trials, Phase III as Topic

2019
Increased compliance with tumor treating fields therapy is prognostic for improved survival in the treatment of glioblastoma: a subgroup analysis of the EF-14 phase III trial.
    Journal of neuro-oncology, 2019, Volume: 141, Issue:2

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Clinical Trials, Phase III as Topic

2019
Increased compliance with tumor treating fields therapy is prognostic for improved survival in the treatment of glioblastoma: a subgroup analysis of the EF-14 phase III trial.
    Journal of neuro-oncology, 2019, Volume: 141, Issue:2

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Clinical Trials, Phase III as Topic

2019
Increased compliance with tumor treating fields therapy is prognostic for improved survival in the treatment of glioblastoma: a subgroup analysis of the EF-14 phase III trial.
    Journal of neuro-oncology, 2019, Volume: 141, Issue:2

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Clinical Trials, Phase III as Topic

2019
Increased compliance with tumor treating fields therapy is prognostic for improved survival in the treatment of glioblastoma: a subgroup analysis of the EF-14 phase III trial.
    Journal of neuro-oncology, 2019, Volume: 141, Issue:2

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Clinical Trials, Phase III as Topic

2019
Increased compliance with tumor treating fields therapy is prognostic for improved survival in the treatment of glioblastoma: a subgroup analysis of the EF-14 phase III trial.
    Journal of neuro-oncology, 2019, Volume: 141, Issue:2

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Clinical Trials, Phase III as Topic

2019
Increased compliance with tumor treating fields therapy is prognostic for improved survival in the treatment of glioblastoma: a subgroup analysis of the EF-14 phase III trial.
    Journal of neuro-oncology, 2019, Volume: 141, Issue:2

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Clinical Trials, Phase III as Topic

2019
Increased compliance with tumor treating fields therapy is prognostic for improved survival in the treatment of glioblastoma: a subgroup analysis of the EF-14 phase III trial.
    Journal of neuro-oncology, 2019, Volume: 141, Issue:2

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Clinical Trials, Phase III as Topic

2019
Increased compliance with tumor treating fields therapy is prognostic for improved survival in the treatment of glioblastoma: a subgroup analysis of the EF-14 phase III trial.
    Journal of neuro-oncology, 2019, Volume: 141, Issue:2

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Clinical Trials, Phase III as Topic

2019
Re-irradiation for recurrent glioma: outcome evaluation, toxicity and prognostic factors assessment. A multicenter study of the Radiation Oncology Italian Association (AIRO).
    Journal of neuro-oncology, 2019, Volume: 142, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modalit

2019
Re-irradiation for recurrent glioma: outcome evaluation, toxicity and prognostic factors assessment. A multicenter study of the Radiation Oncology Italian Association (AIRO).
    Journal of neuro-oncology, 2019, Volume: 142, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modalit

2019
Re-irradiation for recurrent glioma: outcome evaluation, toxicity and prognostic factors assessment. A multicenter study of the Radiation Oncology Italian Association (AIRO).
    Journal of neuro-oncology, 2019, Volume: 142, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modalit

2019
BET inhibitor I-BET151 sensitizes GBM cells to temozolomide via PUMA induction.
    Cancer gene therapy, 2020, Volume: 27, Issue:3-4

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Apoptosis Regulatory Proteins; B

2020
BET inhibitor I-BET151 sensitizes GBM cells to temozolomide via PUMA induction.
    Cancer gene therapy, 2020, Volume: 27, Issue:3-4

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Apoptosis Regulatory Proteins; B

2020
BET inhibitor I-BET151 sensitizes GBM cells to temozolomide via PUMA induction.
    Cancer gene therapy, 2020, Volume: 27, Issue:3-4

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Apoptosis Regulatory Proteins; B

2020
Association of patterns of care, prognostic factors, and use of radiotherapy-temozolomide therapy with survival in patients with newly diagnosed glioblastoma: a French national population-based study.
    Journal of neuro-oncology, 2019, Volume: 142, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modalit

2019
Association of patterns of care, prognostic factors, and use of radiotherapy-temozolomide therapy with survival in patients with newly diagnosed glioblastoma: a French national population-based study.
    Journal of neuro-oncology, 2019, Volume: 142, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modalit

2019
Association of patterns of care, prognostic factors, and use of radiotherapy-temozolomide therapy with survival in patients with newly diagnosed glioblastoma: a French national population-based study.
    Journal of neuro-oncology, 2019, Volume: 142, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modalit

2019
PLK4 is a determinant of temozolomide sensitivity through phosphorylation of IKBKE in glioblastoma.
    Cancer letters, 2019, 02-28, Volume: 443

    Topics: Adolescent; Adult; Aged; Animals; Brain Neoplasms; Cell Line, Tumor; Child; Disease Progression; Dru

2019
PLK4 is a determinant of temozolomide sensitivity through phosphorylation of IKBKE in glioblastoma.
    Cancer letters, 2019, 02-28, Volume: 443

    Topics: Adolescent; Adult; Aged; Animals; Brain Neoplasms; Cell Line, Tumor; Child; Disease Progression; Dru

2019
PLK4 is a determinant of temozolomide sensitivity through phosphorylation of IKBKE in glioblastoma.
    Cancer letters, 2019, 02-28, Volume: 443

    Topics: Adolescent; Adult; Aged; Animals; Brain Neoplasms; Cell Line, Tumor; Child; Disease Progression; Dru

2019
Piezoelectric barium titanate nanostimulators for the treatment of glioblastoma multiforme.
    Journal of colloid and interface science, 2019, Mar-07, Volume: 538

    Topics: Antineoplastic Agents, Alkylating; Apoptosis; Barium Compounds; Blood-Brain Barrier; Brain Neoplasms

2019
Piezoelectric barium titanate nanostimulators for the treatment of glioblastoma multiforme.
    Journal of colloid and interface science, 2019, Mar-07, Volume: 538

    Topics: Antineoplastic Agents, Alkylating; Apoptosis; Barium Compounds; Blood-Brain Barrier; Brain Neoplasms

2019
Piezoelectric barium titanate nanostimulators for the treatment of glioblastoma multiforme.
    Journal of colloid and interface science, 2019, Mar-07, Volume: 538

    Topics: Antineoplastic Agents, Alkylating; Apoptosis; Barium Compounds; Blood-Brain Barrier; Brain Neoplasms

2019
A prospective longitudinal evaluation of cognition and depression in postoperative patients with high-grade glioma following radiotherapy and chemotherapy.
    Journal of cancer research and therapeutics, 2018, Volume: 14, Issue:Supplement

    Topics: Adult; Antineoplastic Agents, Alkylating; Brain; Brain Neoplasms; Chemoradiotherapy, Adjuvant; Cogni

2018
A prospective longitudinal evaluation of cognition and depression in postoperative patients with high-grade glioma following radiotherapy and chemotherapy.
    Journal of cancer research and therapeutics, 2018, Volume: 14, Issue:Supplement

    Topics: Adult; Antineoplastic Agents, Alkylating; Brain; Brain Neoplasms; Chemoradiotherapy, Adjuvant; Cogni

2018
A prospective longitudinal evaluation of cognition and depression in postoperative patients with high-grade glioma following radiotherapy and chemotherapy.
    Journal of cancer research and therapeutics, 2018, Volume: 14, Issue:Supplement

    Topics: Adult; Antineoplastic Agents, Alkylating; Brain; Brain Neoplasms; Chemoradiotherapy, Adjuvant; Cogni

2018
Efficacy of arginine depletion by ADI-PEG20 in an intracranial model of GBM.
    Cell death & disease, 2018, 12-13, Volume: 9, Issue:12

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Arginine; Argininosuccinate Synthase; Brain

2018
Efficacy of arginine depletion by ADI-PEG20 in an intracranial model of GBM.
    Cell death & disease, 2018, 12-13, Volume: 9, Issue:12

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Arginine; Argininosuccinate Synthase; Brain

2018
Efficacy of arginine depletion by ADI-PEG20 in an intracranial model of GBM.
    Cell death & disease, 2018, 12-13, Volume: 9, Issue:12

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Arginine; Argininosuccinate Synthase; Brain

2018
MiR-181b-5p modulates chemosensitivity of glioma cells to temozolomide by targeting Bcl-2.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2019, Volume: 109

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Cell Survival; Dose-R

2019
MiR-181b-5p modulates chemosensitivity of glioma cells to temozolomide by targeting Bcl-2.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2019, Volume: 109

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Cell Survival; Dose-R

2019
MiR-181b-5p modulates chemosensitivity of glioma cells to temozolomide by targeting Bcl-2.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2019, Volume: 109

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Cell Survival; Dose-R

2019
Cell quiescence correlates with enhanced glioblastoma cell invasion and cytotoxic resistance.
    Experimental cell research, 2019, 01-15, Volume: 374, Issue:2

    Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Cell Division; Cell Line, Tumor; Cell Movement; Cel

2019
Cell quiescence correlates with enhanced glioblastoma cell invasion and cytotoxic resistance.
    Experimental cell research, 2019, 01-15, Volume: 374, Issue:2

    Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Cell Division; Cell Line, Tumor; Cell Movement; Cel

2019
Cell quiescence correlates with enhanced glioblastoma cell invasion and cytotoxic resistance.
    Experimental cell research, 2019, 01-15, Volume: 374, Issue:2

    Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Cell Division; Cell Line, Tumor; Cell Movement; Cel

2019
Inhibition of Cyclin D1 Expression in Human Glioblastoma Cells is Associated with Increased Temozolomide Chemosensitivity.
    Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 2018, Volume: 51, Issue:6

    Topics: Adult; Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cell Prolife

2018
Inhibition of Cyclin D1 Expression in Human Glioblastoma Cells is Associated with Increased Temozolomide Chemosensitivity.
    Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 2018, Volume: 51, Issue:6

    Topics: Adult; Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cell Prolife

2018
Inhibition of Cyclin D1 Expression in Human Glioblastoma Cells is Associated with Increased Temozolomide Chemosensitivity.
    Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 2018, Volume: 51, Issue:6

    Topics: Adult; Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cell Prolife

2018
Study on Therapeutic Action and Mechanism of TMZ Combined with RITA Against Glioblastoma.
    Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 2018, Volume: 51, Issue:6

    Topics: Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation;

2018
Study on Therapeutic Action and Mechanism of TMZ Combined with RITA Against Glioblastoma.
    Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 2018, Volume: 51, Issue:6

    Topics: Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation;

2018
Study on Therapeutic Action and Mechanism of TMZ Combined with RITA Against Glioblastoma.
    Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 2018, Volume: 51, Issue:6

    Topics: Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation;

2018
The HIF‑1α/miR‑224‑3p/ATG5 axis affects cell mobility and chemosensitivity by regulating hypoxia‑induced protective autophagy in glioblastoma and astrocytoma.
    Oncology reports, 2019, Volume: 41, Issue:3

    Topics: Adult; Animals; Antineoplastic Agents, Alkylating; Astrocytoma; Autophagy; Autophagy-Related Protein

2019
The HIF‑1α/miR‑224‑3p/ATG5 axis affects cell mobility and chemosensitivity by regulating hypoxia‑induced protective autophagy in glioblastoma and astrocytoma.
    Oncology reports, 2019, Volume: 41, Issue:3

    Topics: Adult; Animals; Antineoplastic Agents, Alkylating; Astrocytoma; Autophagy; Autophagy-Related Protein

2019
The HIF‑1α/miR‑224‑3p/ATG5 axis affects cell mobility and chemosensitivity by regulating hypoxia‑induced protective autophagy in glioblastoma and astrocytoma.
    Oncology reports, 2019, Volume: 41, Issue:3

    Topics: Adult; Animals; Antineoplastic Agents, Alkylating; Astrocytoma; Autophagy; Autophagy-Related Protein

2019
Local delivery of temozolomide via a biologically inert carrier (Temodex) prolongs survival in glioma patients, irrespectively of the methylation status of MGMT.
    Neoplasma, 2019, Mar-05, Volume: 66, Issue:2

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; DNA Methylation; DNA Modification Methylases; DN

2019
Local delivery of temozolomide via a biologically inert carrier (Temodex) prolongs survival in glioma patients, irrespectively of the methylation status of MGMT.
    Neoplasma, 2019, Mar-05, Volume: 66, Issue:2

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; DNA Methylation; DNA Modification Methylases; DN

2019
Local delivery of temozolomide via a biologically inert carrier (Temodex) prolongs survival in glioma patients, irrespectively of the methylation status of MGMT.
    Neoplasma, 2019, Mar-05, Volume: 66, Issue:2

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; DNA Methylation; DNA Modification Methylases; DN

2019
Knockdown of SLC34A2 inhibits cell proliferation, metastasis, and elevates chemosensitivity in glioma.
    Journal of cellular biochemistry, 2019, Volume: 120, Issue:6

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Cell Movement; Cell P

2019
Knockdown of SLC34A2 inhibits cell proliferation, metastasis, and elevates chemosensitivity in glioma.
    Journal of cellular biochemistry, 2019, Volume: 120, Issue:6

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Cell Movement; Cell P

2019
Knockdown of SLC34A2 inhibits cell proliferation, metastasis, and elevates chemosensitivity in glioma.
    Journal of cellular biochemistry, 2019, Volume: 120, Issue:6

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Cell Movement; Cell P

2019
Delivery of liposome encapsulated temozolomide to brain tumour: Understanding the drug transport for optimisation.
    International journal of pharmaceutics, 2019, Feb-25, Volume: 557

    Topics: Administration, Intravenous; Administration, Oral; Antineoplastic Agents, Alkylating; Biological Tra

2019
Delivery of liposome encapsulated temozolomide to brain tumour: Understanding the drug transport for optimisation.
    International journal of pharmaceutics, 2019, Feb-25, Volume: 557

    Topics: Administration, Intravenous; Administration, Oral; Antineoplastic Agents, Alkylating; Biological Tra

2019
Delivery of liposome encapsulated temozolomide to brain tumour: Understanding the drug transport for optimisation.
    International journal of pharmaceutics, 2019, Feb-25, Volume: 557

    Topics: Administration, Intravenous; Administration, Oral; Antineoplastic Agents, Alkylating; Biological Tra

2019
Isofuranodiene synergizes with temozolomide in inducing glioma cells death.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2019, Volume: 52

    Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Brain Neoplasms; Cell Death; Cell Line, Tumor; Cell Su

2019
Isofuranodiene synergizes with temozolomide in inducing glioma cells death.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2019, Volume: 52

    Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Brain Neoplasms; Cell Death; Cell Line, Tumor; Cell Su

2019
Isofuranodiene synergizes with temozolomide in inducing glioma cells death.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2019, Volume: 52

    Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Brain Neoplasms; Cell Death; Cell Line, Tumor; Cell Su

2019
Biodegradable wafers releasing Temozolomide and Carmustine for the treatment of brain cancer.
    Journal of controlled release : official journal of the Controlled Release Society, 2019, 02-10, Volume: 295

    Topics: Animals; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Brain Ne

2019
Biodegradable wafers releasing Temozolomide and Carmustine for the treatment of brain cancer.
    Journal of controlled release : official journal of the Controlled Release Society, 2019, 02-10, Volume: 295

    Topics: Animals; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Brain Ne

2019
Biodegradable wafers releasing Temozolomide and Carmustine for the treatment of brain cancer.
    Journal of controlled release : official journal of the Controlled Release Society, 2019, 02-10, Volume: 295

    Topics: Animals; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Brain Ne

2019
Conventionally fractionated stereotactic radiotherapy (CFRT) in combination with dose-dense temozolomide (TMZ) in relapsed malignant glioma: A case report.
    Medicine, 2019, Volume: 98, Issue:1

    Topics: Adult; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Female; Gliobl

2019
Conventionally fractionated stereotactic radiotherapy (CFRT) in combination with dose-dense temozolomide (TMZ) in relapsed malignant glioma: A case report.
    Medicine, 2019, Volume: 98, Issue:1

    Topics: Adult; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Female; Gliobl

2019
Conventionally fractionated stereotactic radiotherapy (CFRT) in combination with dose-dense temozolomide (TMZ) in relapsed malignant glioma: A case report.
    Medicine, 2019, Volume: 98, Issue:1

    Topics: Adult; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Female; Gliobl

2019
Downregulation of miR-196b Promotes Glioma Cell Sensitivity to Temozolomide Chemotherapy and Radiotherapy.
    Annals of clinical and laboratory science, 2018, Volume: 48, Issue:6

    Topics: Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Caspase 3; Caspase 7; Cell Line, Tumo

2018
Downregulation of miR-196b Promotes Glioma Cell Sensitivity to Temozolomide Chemotherapy and Radiotherapy.
    Annals of clinical and laboratory science, 2018, Volume: 48, Issue:6

    Topics: Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Caspase 3; Caspase 7; Cell Line, Tumo

2018
Downregulation of miR-196b Promotes Glioma Cell Sensitivity to Temozolomide Chemotherapy and Radiotherapy.
    Annals of clinical and laboratory science, 2018, Volume: 48, Issue:6

    Topics: Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Caspase 3; Caspase 7; Cell Line, Tumo

2018
Optimal extent of resection for glioblastoma according to site, extension, and size: a population-based study in the temozolomide era.
    Neurosurgical review, 2019, Volume: 42, Issue:4

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Biopsy; Brain Neoplasms; Female; Glioblastoma; Human

2019
Optimal extent of resection for glioblastoma according to site, extension, and size: a population-based study in the temozolomide era.
    Neurosurgical review, 2019, Volume: 42, Issue:4

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Biopsy; Brain Neoplasms; Female; Glioblastoma; Human

2019
Optimal extent of resection for glioblastoma according to site, extension, and size: a population-based study in the temozolomide era.
    Neurosurgical review, 2019, Volume: 42, Issue:4

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Biopsy; Brain Neoplasms; Female; Glioblastoma; Human

2019
Medroxyprogesterone effects on colony growth, autophagy and mitochondria of C6 glioma cells are augmented with tibolone and temozolomide: Cell kinetic and electron microscopical studies with a broad review of the literature.
    Clinical neurology and neurosurgery, 2019, Volume: 177

    Topics: Autophagy; Brain Neoplasms; Glioblastoma; Glioma; Humans; Medroxyprogesterone; Medroxyprogesterone A

2019
Medroxyprogesterone effects on colony growth, autophagy and mitochondria of C6 glioma cells are augmented with tibolone and temozolomide: Cell kinetic and electron microscopical studies with a broad review of the literature.
    Clinical neurology and neurosurgery, 2019, Volume: 177

    Topics: Autophagy; Brain Neoplasms; Glioblastoma; Glioma; Humans; Medroxyprogesterone; Medroxyprogesterone A

2019
Medroxyprogesterone effects on colony growth, autophagy and mitochondria of C6 glioma cells are augmented with tibolone and temozolomide: Cell kinetic and electron microscopical studies with a broad review of the literature.
    Clinical neurology and neurosurgery, 2019, Volume: 177

    Topics: Autophagy; Brain Neoplasms; Glioblastoma; Glioma; Humans; Medroxyprogesterone; Medroxyprogesterone A

2019
[Temozolomide (TMZ)].
    Nihon rinsho. Japanese journal of clinical medicine, 2016, Volume: 74 Suppl 7

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Humans; Temozolomide

2016
[Temozolomide (TMZ)].
    Nihon rinsho. Japanese journal of clinical medicine, 2016, Volume: 74 Suppl 7

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Humans; Temozolomide

2016
[Temozolomide (TMZ)].
    Nihon rinsho. Japanese journal of clinical medicine, 2016, Volume: 74 Suppl 7

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Humans; Temozolomide

2016
Increased Expression of GRP78 Correlates with Adverse Outcome in Recurrent Glioblastoma Multiforme Patients.
    Turkish neurosurgery, 2020, Volume: 30, Issue:1

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Biomarkers, Tumor; Brain Neoplasms; Chemoradiotherap

2020
Increased Expression of GRP78 Correlates with Adverse Outcome in Recurrent Glioblastoma Multiforme Patients.
    Turkish neurosurgery, 2020, Volume: 30, Issue:1

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Biomarkers, Tumor; Brain Neoplasms; Chemoradiotherap

2020
Increased Expression of GRP78 Correlates with Adverse Outcome in Recurrent Glioblastoma Multiforme Patients.
    Turkish neurosurgery, 2020, Volume: 30, Issue:1

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Biomarkers, Tumor; Brain Neoplasms; Chemoradiotherap

2020
MCCK1 enhances the anticancer effect of temozolomide in attenuating the invasion, migration and epithelial-mesenchymal transition of glioblastoma cells in vitro and in vivo.
    Cancer medicine, 2019, Volume: 8, Issue:2

    Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Brain Neo

2019
MCCK1 enhances the anticancer effect of temozolomide in attenuating the invasion, migration and epithelial-mesenchymal transition of glioblastoma cells in vitro and in vivo.
    Cancer medicine, 2019, Volume: 8, Issue:2

    Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Brain Neo

2019
MCCK1 enhances the anticancer effect of temozolomide in attenuating the invasion, migration and epithelial-mesenchymal transition of glioblastoma cells in vitro and in vivo.
    Cancer medicine, 2019, Volume: 8, Issue:2

    Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Brain Neo

2019
Momelotinib sensitizes glioblastoma cells to temozolomide by enhancement of autophagy via JAK2/STAT3 inhibition.
    Oncology reports, 2019, Volume: 41, Issue:3

    Topics: Adult; Animals; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; A

2019
Momelotinib sensitizes glioblastoma cells to temozolomide by enhancement of autophagy via JAK2/STAT3 inhibition.
    Oncology reports, 2019, Volume: 41, Issue:3

    Topics: Adult; Animals; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; A

2019
Momelotinib sensitizes glioblastoma cells to temozolomide by enhancement of autophagy via JAK2/STAT3 inhibition.
    Oncology reports, 2019, Volume: 41, Issue:3

    Topics: Adult; Animals; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; A

2019
Modulation of temozolomide dose differentially affects T-cell response to immune checkpoint inhibition.
    Neuro-oncology, 2019, 06-10, Volume: 21, Issue:6

    Topics: Animals; Antibodies, Monoclonal; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dose-Response R

2019
Modulation of temozolomide dose differentially affects T-cell response to immune checkpoint inhibition.
    Neuro-oncology, 2019, 06-10, Volume: 21, Issue:6

    Topics: Animals; Antibodies, Monoclonal; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dose-Response R

2019
Modulation of temozolomide dose differentially affects T-cell response to immune checkpoint inhibition.
    Neuro-oncology, 2019, 06-10, Volume: 21, Issue:6

    Topics: Animals; Antibodies, Monoclonal; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dose-Response R

2019
Blood-Brain Barrier Opening in Primary Brain Tumors with Non-invasive MR-Guided Focused Ultrasound: A Clinical Safety and Feasibility Study.
    Scientific reports, 2019, 01-23, Volume: 9, Issue:1

    Topics: Adult; Aged; Animals; Antineoplastic Agents; Blood-Brain Barrier; Brain Neoplasms; Doxorubicin; Drug

2019
Blood-Brain Barrier Opening in Primary Brain Tumors with Non-invasive MR-Guided Focused Ultrasound: A Clinical Safety and Feasibility Study.
    Scientific reports, 2019, 01-23, Volume: 9, Issue:1

    Topics: Adult; Aged; Animals; Antineoplastic Agents; Blood-Brain Barrier; Brain Neoplasms; Doxorubicin; Drug

2019
Blood-Brain Barrier Opening in Primary Brain Tumors with Non-invasive MR-Guided Focused Ultrasound: A Clinical Safety and Feasibility Study.
    Scientific reports, 2019, 01-23, Volume: 9, Issue:1

    Topics: Adult; Aged; Animals; Antineoplastic Agents; Blood-Brain Barrier; Brain Neoplasms; Doxorubicin; Drug

2019
Blood-Brain Barrier Opening in Primary Brain Tumors with Non-invasive MR-Guided Focused Ultrasound: A Clinical Safety and Feasibility Study.
    Scientific reports, 2019, 01-23, Volume: 9, Issue:1

    Topics: Adult; Aged; Animals; Antineoplastic Agents; Blood-Brain Barrier; Brain Neoplasms; Doxorubicin; Drug

2019
Blood-Brain Barrier Opening in Primary Brain Tumors with Non-invasive MR-Guided Focused Ultrasound: A Clinical Safety and Feasibility Study.
    Scientific reports, 2019, 01-23, Volume: 9, Issue:1

    Topics: Adult; Aged; Animals; Antineoplastic Agents; Blood-Brain Barrier; Brain Neoplasms; Doxorubicin; Drug

2019
Blood-Brain Barrier Opening in Primary Brain Tumors with Non-invasive MR-Guided Focused Ultrasound: A Clinical Safety and Feasibility Study.
    Scientific reports, 2019, 01-23, Volume: 9, Issue:1

    Topics: Adult; Aged; Animals; Antineoplastic Agents; Blood-Brain Barrier; Brain Neoplasms; Doxorubicin; Drug

2019
Blood-Brain Barrier Opening in Primary Brain Tumors with Non-invasive MR-Guided Focused Ultrasound: A Clinical Safety and Feasibility Study.
    Scientific reports, 2019, 01-23, Volume: 9, Issue:1

    Topics: Adult; Aged; Animals; Antineoplastic Agents; Blood-Brain Barrier; Brain Neoplasms; Doxorubicin; Drug

2019
Blood-Brain Barrier Opening in Primary Brain Tumors with Non-invasive MR-Guided Focused Ultrasound: A Clinical Safety and Feasibility Study.
    Scientific reports, 2019, 01-23, Volume: 9, Issue:1

    Topics: Adult; Aged; Animals; Antineoplastic Agents; Blood-Brain Barrier; Brain Neoplasms; Doxorubicin; Drug

2019
Blood-Brain Barrier Opening in Primary Brain Tumors with Non-invasive MR-Guided Focused Ultrasound: A Clinical Safety and Feasibility Study.
    Scientific reports, 2019, 01-23, Volume: 9, Issue:1

    Topics: Adult; Aged; Animals; Antineoplastic Agents; Blood-Brain Barrier; Brain Neoplasms; Doxorubicin; Drug

2019
Blood-Brain Barrier Opening in Primary Brain Tumors with Non-invasive MR-Guided Focused Ultrasound: A Clinical Safety and Feasibility Study.
    Scientific reports, 2019, 01-23, Volume: 9, Issue:1

    Topics: Adult; Aged; Animals; Antineoplastic Agents; Blood-Brain Barrier; Brain Neoplasms; Doxorubicin; Drug

2019
Blood-Brain Barrier Opening in Primary Brain Tumors with Non-invasive MR-Guided Focused Ultrasound: A Clinical Safety and Feasibility Study.
    Scientific reports, 2019, 01-23, Volume: 9, Issue:1

    Topics: Adult; Aged; Animals; Antineoplastic Agents; Blood-Brain Barrier; Brain Neoplasms; Doxorubicin; Drug

2019
Blood-Brain Barrier Opening in Primary Brain Tumors with Non-invasive MR-Guided Focused Ultrasound: A Clinical Safety and Feasibility Study.
    Scientific reports, 2019, 01-23, Volume: 9, Issue:1

    Topics: Adult; Aged; Animals; Antineoplastic Agents; Blood-Brain Barrier; Brain Neoplasms; Doxorubicin; Drug

2019
Influence of molecular classification in anaplastic glioma for determining outcome and future approach to management.
    Journal of medical imaging and radiation oncology, 2019, Volume: 63, Issue:2

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Contrast

2019
Influence of molecular classification in anaplastic glioma for determining outcome and future approach to management.
    Journal of medical imaging and radiation oncology, 2019, Volume: 63, Issue:2

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Contrast

2019
Influence of molecular classification in anaplastic glioma for determining outcome and future approach to management.
    Journal of medical imaging and radiation oncology, 2019, Volume: 63, Issue:2

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Contrast

2019
The functional synergism of microRNA clustering provides therapeutically relevant epigenetic interference in glioblastoma.
    Nature communications, 2019, 01-25, Volume: 10, Issue:1

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; C

2019
The functional synergism of microRNA clustering provides therapeutically relevant epigenetic interference in glioblastoma.
    Nature communications, 2019, 01-25, Volume: 10, Issue:1

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; C

2019
The functional synergism of microRNA clustering provides therapeutically relevant epigenetic interference in glioblastoma.
    Nature communications, 2019, 01-25, Volume: 10, Issue:1

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; C

2019
Glioblastoma Treatment with Temozolomide and Bevacizumab and Overall Survival in a Rural Tertiary Healthcare Practice.
    BioMed research international, 2018, Volume: 2018

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bevacizu

2018
Glioblastoma Treatment with Temozolomide and Bevacizumab and Overall Survival in a Rural Tertiary Healthcare Practice.
    BioMed research international, 2018, Volume: 2018

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bevacizu

2018
Glioblastoma Treatment with Temozolomide and Bevacizumab and Overall Survival in a Rural Tertiary Healthcare Practice.
    BioMed research international, 2018, Volume: 2018

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bevacizu

2018
A novel 3D in vitro model of glioblastoma reveals resistance to temozolomide which was potentiated by hypoxia.
    Journal of neuro-oncology, 2019, Volume: 142, Issue:2

    Topics: AC133 Antigen; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Culture Techniques; Cell Hyp

2019
A novel 3D in vitro model of glioblastoma reveals resistance to temozolomide which was potentiated by hypoxia.
    Journal of neuro-oncology, 2019, Volume: 142, Issue:2

    Topics: AC133 Antigen; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Culture Techniques; Cell Hyp

2019
A novel 3D in vitro model of glioblastoma reveals resistance to temozolomide which was potentiated by hypoxia.
    Journal of neuro-oncology, 2019, Volume: 142, Issue:2

    Topics: AC133 Antigen; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Culture Techniques; Cell Hyp

2019
Targeted and Synergic Glioblastoma Treatment: Multifunctional Nanoparticles Delivering Verteporfin as Adjuvant Therapy for Temozolomide Chemotherapy.
    Molecular pharmaceutics, 2019, 03-04, Volume: 16, Issue:3

    Topics: Animals; Brain Neoplasms; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Survival; Chemotherapy, Adj

2019
Targeted and Synergic Glioblastoma Treatment: Multifunctional Nanoparticles Delivering Verteporfin as Adjuvant Therapy for Temozolomide Chemotherapy.
    Molecular pharmaceutics, 2019, 03-04, Volume: 16, Issue:3

    Topics: Animals; Brain Neoplasms; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Survival; Chemotherapy, Adj

2019
Targeted and Synergic Glioblastoma Treatment: Multifunctional Nanoparticles Delivering Verteporfin as Adjuvant Therapy for Temozolomide Chemotherapy.
    Molecular pharmaceutics, 2019, 03-04, Volume: 16, Issue:3

    Topics: Animals; Brain Neoplasms; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Survival; Chemotherapy, Adj

2019
pH as a potential therapeutic target to improve temozolomide antitumor efficacy : A mechanistic modeling study.
    Pharmacology research & perspectives, 2019, Volume: 7, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Computer Simulation; Cytoplasm

2019
pH as a potential therapeutic target to improve temozolomide antitumor efficacy : A mechanistic modeling study.
    Pharmacology research & perspectives, 2019, Volume: 7, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Computer Simulation; Cytoplasm

2019
pH as a potential therapeutic target to improve temozolomide antitumor efficacy : A mechanistic modeling study.
    Pharmacology research & perspectives, 2019, Volume: 7, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Computer Simulation; Cytoplasm

2019
Crosslink between Temozolomide and PD-L1 immune-checkpoint inhibition in glioblastoma multiforme.
    BMC cancer, 2019, Feb-01, Volume: 19, Issue:1

    Topics: Antineoplastic Agents, Alkylating; B7-H1 Antigen; Brain Neoplasms; Cell Line, Tumor; Gene Expression

2019
Crosslink between Temozolomide and PD-L1 immune-checkpoint inhibition in glioblastoma multiforme.
    BMC cancer, 2019, Feb-01, Volume: 19, Issue:1

    Topics: Antineoplastic Agents, Alkylating; B7-H1 Antigen; Brain Neoplasms; Cell Line, Tumor; Gene Expression

2019
Crosslink between Temozolomide and PD-L1 immune-checkpoint inhibition in glioblastoma multiforme.
    BMC cancer, 2019, Feb-01, Volume: 19, Issue:1

    Topics: Antineoplastic Agents, Alkylating; B7-H1 Antigen; Brain Neoplasms; Cell Line, Tumor; Gene Expression

2019
Leptomeningeal Gliomatosis: A Single Institution Study of 31 Patients.
    Anticancer research, 2019, Volume: 39, Issue:2

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carmustine; Combined M

2019
Leptomeningeal Gliomatosis: A Single Institution Study of 31 Patients.
    Anticancer research, 2019, Volume: 39, Issue:2

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carmustine; Combined M

2019
Leptomeningeal Gliomatosis: A Single Institution Study of 31 Patients.
    Anticancer research, 2019, Volume: 39, Issue:2

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carmustine; Combined M

2019
Determining a cut-off residual tumor volume threshold for patients with newly diagnosed glioblastoma treated with temozolomide chemoradiotherapy: A multicenter cohort study.
    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2019, Volume: 63

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Brain Neoplasms; Chemoradiotherapy, Adjuvant; Cohort Stu

2019
Determining a cut-off residual tumor volume threshold for patients with newly diagnosed glioblastoma treated with temozolomide chemoradiotherapy: A multicenter cohort study.
    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2019, Volume: 63

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Brain Neoplasms; Chemoradiotherapy, Adjuvant; Cohort Stu

2019
Determining a cut-off residual tumor volume threshold for patients with newly diagnosed glioblastoma treated with temozolomide chemoradiotherapy: A multicenter cohort study.
    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2019, Volume: 63

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Brain Neoplasms; Chemoradiotherapy, Adjuvant; Cohort Stu

2019
Dissociation Between 11C-Methionine-Positron Emission Tomography and Gadolinium-Enhanced Magnetic Resonance Imaging in Longitudinal Features of Glioblastoma After Postoperative Radiotherapy.
    World neurosurgery, 2019, Volume: 125

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Contrast

2019
Dissociation Between 11C-Methionine-Positron Emission Tomography and Gadolinium-Enhanced Magnetic Resonance Imaging in Longitudinal Features of Glioblastoma After Postoperative Radiotherapy.
    World neurosurgery, 2019, Volume: 125

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Contrast

2019
Dissociation Between 11C-Methionine-Positron Emission Tomography and Gadolinium-Enhanced Magnetic Resonance Imaging in Longitudinal Features of Glioblastoma After Postoperative Radiotherapy.
    World neurosurgery, 2019, Volume: 125

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Contrast

2019
The Impact of
    Medicina (Kaunas, Lithuania), 2019, Feb-01, Volume: 55, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Biomarkers, Tumor; Brain Neoplasm

2019
The Impact of
    Medicina (Kaunas, Lithuania), 2019, Feb-01, Volume: 55, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Biomarkers, Tumor; Brain Neoplasm

2019
The Impact of
    Medicina (Kaunas, Lithuania), 2019, Feb-01, Volume: 55, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Biomarkers, Tumor; Brain Neoplasm

2019
A Human iPSC-derived 3D platform using primary brain cancer cells to study drug development and personalized medicine.
    Scientific reports, 2019, 02-05, Volume: 9, Issue:1

    Topics: Antibiotics, Antineoplastic; Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cell Lin

2019
A Human iPSC-derived 3D platform using primary brain cancer cells to study drug development and personalized medicine.
    Scientific reports, 2019, 02-05, Volume: 9, Issue:1

    Topics: Antibiotics, Antineoplastic; Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cell Lin

2019
A Human iPSC-derived 3D platform using primary brain cancer cells to study drug development and personalized medicine.
    Scientific reports, 2019, 02-05, Volume: 9, Issue:1

    Topics: Antibiotics, Antineoplastic; Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cell Lin

2019
The physiological mTOR complex 1 inhibitor DDIT4 mediates therapy resistance in glioblastoma.
    British journal of cancer, 2019, Volume: 120, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; Gli

2019
The physiological mTOR complex 1 inhibitor DDIT4 mediates therapy resistance in glioblastoma.
    British journal of cancer, 2019, Volume: 120, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; Gli

2019
The physiological mTOR complex 1 inhibitor DDIT4 mediates therapy resistance in glioblastoma.
    British journal of cancer, 2019, Volume: 120, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; Gli

2019
Glioblastoma Recurrence and the Role of O
    JCO clinical cancer informatics, 2019, Volume: 3

    Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Cohort Studies; Combined Modality Therapy; DNA Meth

2019
Glioblastoma Recurrence and the Role of O
    JCO clinical cancer informatics, 2019, Volume: 3

    Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Cohort Studies; Combined Modality Therapy; DNA Meth

2019
Glioblastoma Recurrence and the Role of O
    JCO clinical cancer informatics, 2019, Volume: 3

    Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Cohort Studies; Combined Modality Therapy; DNA Meth

2019
Postsurgical Approaches in Low-Grade Oligodendroglioma: Is Chemotherapy Alone Still an Option?
    The oncologist, 2019, Volume: 24, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Brain; Brain Neoplas

2019
Postsurgical Approaches in Low-Grade Oligodendroglioma: Is Chemotherapy Alone Still an Option?
    The oncologist, 2019, Volume: 24, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Brain; Brain Neoplas

2019
Postsurgical Approaches in Low-Grade Oligodendroglioma: Is Chemotherapy Alone Still an Option?
    The oncologist, 2019, Volume: 24, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Brain; Brain Neoplas

2019
Improving survival in molecularly selected glioblastoma.
    Lancet (London, England), 2019, 02-16, Volume: 393, Issue:10172

    Topics: Adult; Brain Neoplasms; Combined Modality Therapy; DNA Modification Methylases; DNA Repair Enzymes;

2019
Improving survival in molecularly selected glioblastoma.
    Lancet (London, England), 2019, 02-16, Volume: 393, Issue:10172

    Topics: Adult; Brain Neoplasms; Combined Modality Therapy; DNA Modification Methylases; DNA Repair Enzymes;

2019
Improving survival in molecularly selected glioblastoma.
    Lancet (London, England), 2019, 02-16, Volume: 393, Issue:10172

    Topics: Adult; Brain Neoplasms; Combined Modality Therapy; DNA Modification Methylases; DNA Repair Enzymes;

2019
Oroxylin A increases the sensitivity of temozolomide on glioma cells by hypoxia-inducible factor 1α/hedgehog pathway under hypoxia.
    Journal of cellular physiology, 2019, Volume: 234, Issue:10

    Topics: Animals; Brain Neoplasms; Cell Movement; Cell Proliferation; Flavonoids; Gene Expression Regulation,

2019
Oroxylin A increases the sensitivity of temozolomide on glioma cells by hypoxia-inducible factor 1α/hedgehog pathway under hypoxia.
    Journal of cellular physiology, 2019, Volume: 234, Issue:10

    Topics: Animals; Brain Neoplasms; Cell Movement; Cell Proliferation; Flavonoids; Gene Expression Regulation,

2019
Oroxylin A increases the sensitivity of temozolomide on glioma cells by hypoxia-inducible factor 1α/hedgehog pathway under hypoxia.
    Journal of cellular physiology, 2019, Volume: 234, Issue:10

    Topics: Animals; Brain Neoplasms; Cell Movement; Cell Proliferation; Flavonoids; Gene Expression Regulation,

2019
Lomustine-temozolomide combination efficacious in newly diagnosed glioblastoma.
    Nature reviews. Clinical oncology, 2019, Volume: 16, Issue:5

    Topics: Brain Neoplasms; Clinical Trials, Phase III as Topic; DNA Methylation; DNA Modification Methylases;

2019
Lomustine-temozolomide combination efficacious in newly diagnosed glioblastoma.
    Nature reviews. Clinical oncology, 2019, Volume: 16, Issue:5

    Topics: Brain Neoplasms; Clinical Trials, Phase III as Topic; DNA Methylation; DNA Modification Methylases;

2019
Lomustine-temozolomide combination efficacious in newly diagnosed glioblastoma.
    Nature reviews. Clinical oncology, 2019, Volume: 16, Issue:5

    Topics: Brain Neoplasms; Clinical Trials, Phase III as Topic; DNA Methylation; DNA Modification Methylases;

2019
Ibudilast sensitizes glioblastoma to temozolomide by targeting Macrophage Migration Inhibitory Factor (MIF).
    Scientific reports, 2019, 02-27, Volume: 9, Issue:1

    Topics: Aged; Animals; Antineoplastic Agents; Brain Neoplasms; Cell Line, Tumor; DNA Methylation; DNA Modifi

2019
Ibudilast sensitizes glioblastoma to temozolomide by targeting Macrophage Migration Inhibitory Factor (MIF).
    Scientific reports, 2019, 02-27, Volume: 9, Issue:1

    Topics: Aged; Animals; Antineoplastic Agents; Brain Neoplasms; Cell Line, Tumor; DNA Methylation; DNA Modifi

2019
Ibudilast sensitizes glioblastoma to temozolomide by targeting Macrophage Migration Inhibitory Factor (MIF).
    Scientific reports, 2019, 02-27, Volume: 9, Issue:1

    Topics: Aged; Animals; Antineoplastic Agents; Brain Neoplasms; Cell Line, Tumor; DNA Methylation; DNA Modifi

2019
What is the Role of Tumor-treating Fields in Newly Diagnosed Glioblastoma?
    The neurologist, 2019, Volume: 24, Issue:2

    Topics: Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Electric Stimul

2019
What is the Role of Tumor-treating Fields in Newly Diagnosed Glioblastoma?
    The neurologist, 2019, Volume: 24, Issue:2

    Topics: Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Electric Stimul

2019
What is the Role of Tumor-treating Fields in Newly Diagnosed Glioblastoma?
    The neurologist, 2019, Volume: 24, Issue:2

    Topics: Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Electric Stimul

2019
High density is a property of slow-cycling and treatment-resistant human glioblastoma cells.
    Experimental cell research, 2019, 05-01, Volume: 378, Issue:1

    Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Cell Proliferation; Cell Self Renewal; Drug Resista

2019
High density is a property of slow-cycling and treatment-resistant human glioblastoma cells.
    Experimental cell research, 2019, 05-01, Volume: 378, Issue:1

    Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Cell Proliferation; Cell Self Renewal; Drug Resista

2019
High density is a property of slow-cycling and treatment-resistant human glioblastoma cells.
    Experimental cell research, 2019, 05-01, Volume: 378, Issue:1

    Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Cell Proliferation; Cell Self Renewal; Drug Resista

2019
Development of transferrin-modified poly(lactic-co-glycolic acid) nanoparticles for glioma therapy.
    Anti-cancer drugs, 2019, Volume: 30, Issue:6

    Topics: Animals; Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cell Proliferation; Drug Car

2019
Development of transferrin-modified poly(lactic-co-glycolic acid) nanoparticles for glioma therapy.
    Anti-cancer drugs, 2019, Volume: 30, Issue:6

    Topics: Animals; Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cell Proliferation; Drug Car

2019
Development of transferrin-modified poly(lactic-co-glycolic acid) nanoparticles for glioma therapy.
    Anti-cancer drugs, 2019, Volume: 30, Issue:6

    Topics: Animals; Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cell Proliferation; Drug Car

2019
HERC3-Mediated SMAD7 Ubiquitination Degradation Promotes Autophagy-Induced EMT and Chemoresistance in Glioblastoma.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2019, 06-15, Volume: 25, Issue:12

    Topics: Animals; Antineoplastic Agents, Alkylating; Autophagy; Brain Neoplasms; Cell Line, Tumor; Drug Resis

2019
HERC3-Mediated SMAD7 Ubiquitination Degradation Promotes Autophagy-Induced EMT and Chemoresistance in Glioblastoma.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2019, 06-15, Volume: 25, Issue:12

    Topics: Animals; Antineoplastic Agents, Alkylating; Autophagy; Brain Neoplasms; Cell Line, Tumor; Drug Resis

2019
HERC3-Mediated SMAD7 Ubiquitination Degradation Promotes Autophagy-Induced EMT and Chemoresistance in Glioblastoma.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2019, 06-15, Volume: 25, Issue:12

    Topics: Animals; Antineoplastic Agents, Alkylating; Autophagy; Brain Neoplasms; Cell Line, Tumor; Drug Resis

2019
Tubastatin A, an inhibitor of HDAC6, enhances temozolomide‑induced apoptosis and reverses the malignant phenotype of glioblastoma cells.
    International journal of oncology, 2019, Volume: 54, Issue:5

    Topics: Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Cell Survival; Drug Synergism; Epithelial-Mes

2019
Tubastatin A, an inhibitor of HDAC6, enhances temozolomide‑induced apoptosis and reverses the malignant phenotype of glioblastoma cells.
    International journal of oncology, 2019, Volume: 54, Issue:5

    Topics: Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Cell Survival; Drug Synergism; Epithelial-Mes

2019
Tubastatin A, an inhibitor of HDAC6, enhances temozolomide‑induced apoptosis and reverses the malignant phenotype of glioblastoma cells.
    International journal of oncology, 2019, Volume: 54, Issue:5

    Topics: Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Cell Survival; Drug Synergism; Epithelial-Mes

2019
The lncRNA TP73-AS1 is linked to aggressiveness in glioblastoma and promotes temozolomide resistance in glioblastoma cancer stem cells.
    Cell death & disease, 2019, 03-13, Volume: 10, Issue:3

    Topics: Aldehyde Dehydrogenase 1 Family; Antineoplastic Agents, Alkylating; Biomarkers, Tumor; Brain Neoplas

2019
The lncRNA TP73-AS1 is linked to aggressiveness in glioblastoma and promotes temozolomide resistance in glioblastoma cancer stem cells.
    Cell death & disease, 2019, 03-13, Volume: 10, Issue:3

    Topics: Aldehyde Dehydrogenase 1 Family; Antineoplastic Agents, Alkylating; Biomarkers, Tumor; Brain Neoplas

2019
The lncRNA TP73-AS1 is linked to aggressiveness in glioblastoma and promotes temozolomide resistance in glioblastoma cancer stem cells.
    Cell death & disease, 2019, 03-13, Volume: 10, Issue:3

    Topics: Aldehyde Dehydrogenase 1 Family; Antineoplastic Agents, Alkylating; Biomarkers, Tumor; Brain Neoplas

2019
Triple conjugated carbon dots as a nano-drug delivery model for glioblastoma brain tumors.
    Nanoscale, 2019, Mar-28, Volume: 11, Issue:13

    Topics: Brain Neoplasms; Carbon; Cell Line, Tumor; Cell Proliferation; Cell Survival; Drug Carriers; Drug Sy

2019
Triple conjugated carbon dots as a nano-drug delivery model for glioblastoma brain tumors.
    Nanoscale, 2019, Mar-28, Volume: 11, Issue:13

    Topics: Brain Neoplasms; Carbon; Cell Line, Tumor; Cell Proliferation; Cell Survival; Drug Carriers; Drug Sy

2019
Triple conjugated carbon dots as a nano-drug delivery model for glioblastoma brain tumors.
    Nanoscale, 2019, Mar-28, Volume: 11, Issue:13

    Topics: Brain Neoplasms; Carbon; Cell Line, Tumor; Cell Proliferation; Cell Survival; Drug Carriers; Drug Sy

2019
Targeting NFE2L2, a transcription factor upstream of MMP-2: A potential therapeutic strategy for temozolomide resistant glioblastoma.
    Biochemical pharmacology, 2019, Volume: 164

    Topics: Animals; Antineoplastic Agents, Alkylating; Base Sequence; Brain Neoplasms; Cell Line, Tumor; Cell P

2019
Targeting NFE2L2, a transcription factor upstream of MMP-2: A potential therapeutic strategy for temozolomide resistant glioblastoma.
    Biochemical pharmacology, 2019, Volume: 164

    Topics: Animals; Antineoplastic Agents, Alkylating; Base Sequence; Brain Neoplasms; Cell Line, Tumor; Cell P

2019
Targeting NFE2L2, a transcription factor upstream of MMP-2: A potential therapeutic strategy for temozolomide resistant glioblastoma.
    Biochemical pharmacology, 2019, Volume: 164

    Topics: Animals; Antineoplastic Agents, Alkylating; Base Sequence; Brain Neoplasms; Cell Line, Tumor; Cell P

2019
D,L-Methadone does not improve radio- and chemotherapy in glioblastoma in vitro.
    Cancer chemotherapy and pharmacology, 2019, Volume: 83, Issue:6

    Topics: Adult; Aged; Analgesics, Opioid; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Ce

2019
D,L-Methadone does not improve radio- and chemotherapy in glioblastoma in vitro.
    Cancer chemotherapy and pharmacology, 2019, Volume: 83, Issue:6

    Topics: Adult; Aged; Analgesics, Opioid; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Ce

2019
D,L-Methadone does not improve radio- and chemotherapy in glioblastoma in vitro.
    Cancer chemotherapy and pharmacology, 2019, Volume: 83, Issue:6

    Topics: Adult; Aged; Analgesics, Opioid; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Ce

2019
CtIP contributes to non-homologous end joining formation through interacting with ligase IV and promotion of TMZ resistance in glioma cells.
    European review for medical and pharmacological sciences, 2019, Volume: 23, Issue:5

    Topics: Brain Neoplasms; Cell Line, Tumor; Cell Survival; DNA End-Joining Repair; DNA Ligase ATP; Drug Resis

2019
CtIP contributes to non-homologous end joining formation through interacting with ligase IV and promotion of TMZ resistance in glioma cells.
    European review for medical and pharmacological sciences, 2019, Volume: 23, Issue:5

    Topics: Brain Neoplasms; Cell Line, Tumor; Cell Survival; DNA End-Joining Repair; DNA Ligase ATP; Drug Resis

2019
CtIP contributes to non-homologous end joining formation through interacting with ligase IV and promotion of TMZ resistance in glioma cells.
    European review for medical and pharmacological sciences, 2019, Volume: 23, Issue:5

    Topics: Brain Neoplasms; Cell Line, Tumor; Cell Survival; DNA End-Joining Repair; DNA Ligase ATP; Drug Resis

2019
A Real-World Claims Analysis of Costs and Patterns of Care in Treated Patients with Glioblastoma Multiforme in the United States.
    Journal of managed care & specialty pharmacy, 2019, Volume: 25, Issue:4

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Brain Neoplasm

2019
A Real-World Claims Analysis of Costs and Patterns of Care in Treated Patients with Glioblastoma Multiforme in the United States.
    Journal of managed care & specialty pharmacy, 2019, Volume: 25, Issue:4

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Brain Neoplasm

2019
A Real-World Claims Analysis of Costs and Patterns of Care in Treated Patients with Glioblastoma Multiforme in the United States.
    Journal of managed care & specialty pharmacy, 2019, Volume: 25, Issue:4

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Brain Neoplasm

2019
Exosomal transfer of miR-1238 contributes to temozolomide-resistance in glioblastoma.
    EBioMedicine, 2019, Volume: 42

    Topics: Animals; Apoptosis; Biological Transport; Biomarkers, Tumor; Brain Neoplasms; Cell Line, Tumor; Cell

2019
Exosomal transfer of miR-1238 contributes to temozolomide-resistance in glioblastoma.
    EBioMedicine, 2019, Volume: 42

    Topics: Animals; Apoptosis; Biological Transport; Biomarkers, Tumor; Brain Neoplasms; Cell Line, Tumor; Cell

2019
Exosomal transfer of miR-1238 contributes to temozolomide-resistance in glioblastoma.
    EBioMedicine, 2019, Volume: 42

    Topics: Animals; Apoptosis; Biological Transport; Biomarkers, Tumor; Brain Neoplasms; Cell Line, Tumor; Cell

2019
Are There Thresholds in Glioblastoma Cell Death Responses Triggered by Temozolomide?
    International journal of molecular sciences, 2019, Mar-28, Volume: 20, Issue:7

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Death; Cell Line, Tumor; Dose-Response Rela

2019
Are There Thresholds in Glioblastoma Cell Death Responses Triggered by Temozolomide?
    International journal of molecular sciences, 2019, Mar-28, Volume: 20, Issue:7

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Death; Cell Line, Tumor; Dose-Response Rela

2019
Are There Thresholds in Glioblastoma Cell Death Responses Triggered by Temozolomide?
    International journal of molecular sciences, 2019, Mar-28, Volume: 20, Issue:7

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Death; Cell Line, Tumor; Dose-Response Rela

2019
Interleukin-8/CXCR2 signaling regulates therapy-induced plasticity and enhances tumorigenicity in glioblastoma.
    Cell death & disease, 2019, 03-29, Volume: 10, Issue:4

    Topics: Animals; Brain Neoplasms; Carcinogenesis; Cell Line, Tumor; Cell Plasticity; Drug Resistance, Neopla

2019
Interleukin-8/CXCR2 signaling regulates therapy-induced plasticity and enhances tumorigenicity in glioblastoma.
    Cell death & disease, 2019, 03-29, Volume: 10, Issue:4

    Topics: Animals; Brain Neoplasms; Carcinogenesis; Cell Line, Tumor; Cell Plasticity; Drug Resistance, Neopla

2019
Interleukin-8/CXCR2 signaling regulates therapy-induced plasticity and enhances tumorigenicity in glioblastoma.
    Cell death & disease, 2019, 03-29, Volume: 10, Issue:4

    Topics: Animals; Brain Neoplasms; Carcinogenesis; Cell Line, Tumor; Cell Plasticity; Drug Resistance, Neopla

2019
Mild thermotherapy and hyperbaric oxygen enhance sensitivity of TMZ/PSi nanoparticles via decreasing the stemness in glioma.
    Journal of nanobiotechnology, 2019, Apr-01, Volume: 17, Issue:1

    Topics: Animals; Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cell Proli

2019
Mild thermotherapy and hyperbaric oxygen enhance sensitivity of TMZ/PSi nanoparticles via decreasing the stemness in glioma.
    Journal of nanobiotechnology, 2019, Apr-01, Volume: 17, Issue:1

    Topics: Animals; Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cell Proli

2019
Mild thermotherapy and hyperbaric oxygen enhance sensitivity of TMZ/PSi nanoparticles via decreasing the stemness in glioma.
    Journal of nanobiotechnology, 2019, Apr-01, Volume: 17, Issue:1

    Topics: Animals; Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cell Proli

2019
How to integrate immunotherapy into standard of care in glioblastoma.
    Neuro-oncology, 2019, 06-10, Volume: 21, Issue:6

    Topics: Brain Neoplasms; Glioblastoma; Humans; Immunotherapy; Standard of Care; T-Lymphocytes; Temozolomide

2019
How to integrate immunotherapy into standard of care in glioblastoma.
    Neuro-oncology, 2019, 06-10, Volume: 21, Issue:6

    Topics: Brain Neoplasms; Glioblastoma; Humans; Immunotherapy; Standard of Care; T-Lymphocytes; Temozolomide

2019
How to integrate immunotherapy into standard of care in glioblastoma.
    Neuro-oncology, 2019, 06-10, Volume: 21, Issue:6

    Topics: Brain Neoplasms; Glioblastoma; Humans; Immunotherapy; Standard of Care; T-Lymphocytes; Temozolomide

2019
Temozolomide Treatment Induces lncRNA MALAT1 in an NF-κB and p53 Codependent Manner in Glioblastoma.
    Cancer research, 2019, 05-15, Volume: 79, Issue:10

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; DNA Damage; Gene Knoc

2019
Temozolomide Treatment Induces lncRNA MALAT1 in an NF-κB and p53 Codependent Manner in Glioblastoma.
    Cancer research, 2019, 05-15, Volume: 79, Issue:10

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; DNA Damage; Gene Knoc

2019
Temozolomide Treatment Induces lncRNA MALAT1 in an NF-κB and p53 Codependent Manner in Glioblastoma.
    Cancer research, 2019, 05-15, Volume: 79, Issue:10

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; DNA Damage; Gene Knoc

2019
Assessment of Early Therapeutic Response to Nitroxoline in Temozolomide-Resistant Glioblastoma by Amide Proton Transfer Imaging: A Preliminary Comparative Study with Diffusion-weighted Imaging.
    Scientific reports, 2019, 04-03, Volume: 9, Issue:1

    Topics: Algorithms; Amides; Animals; Brain Neoplasms; Diffusion Magnetic Resonance Imaging; Glioblastoma; Gl

2019
Assessment of Early Therapeutic Response to Nitroxoline in Temozolomide-Resistant Glioblastoma by Amide Proton Transfer Imaging: A Preliminary Comparative Study with Diffusion-weighted Imaging.
    Scientific reports, 2019, 04-03, Volume: 9, Issue:1

    Topics: Algorithms; Amides; Animals; Brain Neoplasms; Diffusion Magnetic Resonance Imaging; Glioblastoma; Gl

2019
Assessment of Early Therapeutic Response to Nitroxoline in Temozolomide-Resistant Glioblastoma by Amide Proton Transfer Imaging: A Preliminary Comparative Study with Diffusion-weighted Imaging.
    Scientific reports, 2019, 04-03, Volume: 9, Issue:1

    Topics: Algorithms; Amides; Animals; Brain Neoplasms; Diffusion Magnetic Resonance Imaging; Glioblastoma; Gl

2019
Long-term glioblastoma survival following recovery from cytomegalovirus colitis: A case report.
    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2019, Volume: 64

    Topics: Aged; Brain Neoplasms; Chemoradiotherapy; Colitis; Cytomegalovirus Infections; Female; Glioblastoma;

2019
Long-term glioblastoma survival following recovery from cytomegalovirus colitis: A case report.
    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2019, Volume: 64

    Topics: Aged; Brain Neoplasms; Chemoradiotherapy; Colitis; Cytomegalovirus Infections; Female; Glioblastoma;

2019
Long-term glioblastoma survival following recovery from cytomegalovirus colitis: A case report.
    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2019, Volume: 64

    Topics: Aged; Brain Neoplasms; Chemoradiotherapy; Colitis; Cytomegalovirus Infections; Female; Glioblastoma;

2019
Dose-intensified chemoradiation is associated with altered patterns of failure and favorable survival in patients with newly diagnosed glioblastoma.
    Journal of neuro-oncology, 2019, Volume: 143, Issue:2

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Clinical Trials,

2019
Dose-intensified chemoradiation is associated with altered patterns of failure and favorable survival in patients with newly diagnosed glioblastoma.
    Journal of neuro-oncology, 2019, Volume: 143, Issue:2

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Clinical Trials,

2019
Dose-intensified chemoradiation is associated with altered patterns of failure and favorable survival in patients with newly diagnosed glioblastoma.
    Journal of neuro-oncology, 2019, Volume: 143, Issue:2

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Clinical Trials,

2019
Use of metformin and outcome of patients with newly diagnosed glioblastoma: Pooled analysis.
    International journal of cancer, 2020, 02-01, Volume: 146, Issue:3

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Antineoplastic Combin

2020
Use of metformin and outcome of patients with newly diagnosed glioblastoma: Pooled analysis.
    International journal of cancer, 2020, 02-01, Volume: 146, Issue:3

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Antineoplastic Combin

2020
Use of metformin and outcome of patients with newly diagnosed glioblastoma: Pooled analysis.
    International journal of cancer, 2020, 02-01, Volume: 146, Issue:3

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Antineoplastic Combin

2020
miR-126-3p sensitizes glioblastoma cells to temozolomide by inactivating Wnt/β-catenin signaling via targeting SOX2.
    Life sciences, 2019, Jun-01, Volume: 226

    Topics: Antineoplastic Agents, Alkylating; Apoptosis; beta Catenin; Brain Neoplasms; Cell Line, Tumor; Cell

2019
miR-126-3p sensitizes glioblastoma cells to temozolomide by inactivating Wnt/β-catenin signaling via targeting SOX2.
    Life sciences, 2019, Jun-01, Volume: 226

    Topics: Antineoplastic Agents, Alkylating; Apoptosis; beta Catenin; Brain Neoplasms; Cell Line, Tumor; Cell

2019
miR-126-3p sensitizes glioblastoma cells to temozolomide by inactivating Wnt/β-catenin signaling via targeting SOX2.
    Life sciences, 2019, Jun-01, Volume: 226

    Topics: Antineoplastic Agents, Alkylating; Apoptosis; beta Catenin; Brain Neoplasms; Cell Line, Tumor; Cell

2019
Bioengineering fluorescent virus-like particle/RNAi nanocomplexes act synergistically with temozolomide to eradicate brain tumors.
    Nanoscale, 2019, Apr-25, Volume: 11, Issue:17

    Topics: Animals; Apolipoproteins E; Blood-Brain Barrier; Brain Neoplasms; Cell Line, Tumor; Cell Movement; C

2019
Bioengineering fluorescent virus-like particle/RNAi nanocomplexes act synergistically with temozolomide to eradicate brain tumors.
    Nanoscale, 2019, Apr-25, Volume: 11, Issue:17

    Topics: Animals; Apolipoproteins E; Blood-Brain Barrier; Brain Neoplasms; Cell Line, Tumor; Cell Movement; C

2019
Bioengineering fluorescent virus-like particle/RNAi nanocomplexes act synergistically with temozolomide to eradicate brain tumors.
    Nanoscale, 2019, Apr-25, Volume: 11, Issue:17

    Topics: Animals; Apolipoproteins E; Blood-Brain Barrier; Brain Neoplasms; Cell Line, Tumor; Cell Movement; C

2019
Modulation of Antioxidant Potential with Coenzyme Q10 Suppressed Invasion of Temozolomide-Resistant Rat Glioma
    Oxidative medicine and cellular longevity, 2019, Volume: 2019

    Topics: Animals; Antioxidants; Brain Neoplasms; Drug Resistance, Neoplasm; Glioblastoma; Humans; Male; Mice;

2019
Modulation of Antioxidant Potential with Coenzyme Q10 Suppressed Invasion of Temozolomide-Resistant Rat Glioma
    Oxidative medicine and cellular longevity, 2019, Volume: 2019

    Topics: Animals; Antioxidants; Brain Neoplasms; Drug Resistance, Neoplasm; Glioblastoma; Humans; Male; Mice;

2019
Modulation of Antioxidant Potential with Coenzyme Q10 Suppressed Invasion of Temozolomide-Resistant Rat Glioma
    Oxidative medicine and cellular longevity, 2019, Volume: 2019

    Topics: Animals; Antioxidants; Brain Neoplasms; Drug Resistance, Neoplasm; Glioblastoma; Humans; Male; Mice;

2019
Stem cell-associated heterogeneity in Glioblastoma results from intrinsic tumor plasticity shaped by the microenvironment.
    Nature communications, 2019, 04-16, Volume: 10, Issue:1

    Topics: Animals; Antineoplastic Agents, Alkylating; Biopsy; Brain Neoplasms; Cell Line, Tumor; Cell Plastici

2019
Stem cell-associated heterogeneity in Glioblastoma results from intrinsic tumor plasticity shaped by the microenvironment.
    Nature communications, 2019, 04-16, Volume: 10, Issue:1

    Topics: Animals; Antineoplastic Agents, Alkylating; Biopsy; Brain Neoplasms; Cell Line, Tumor; Cell Plastici

2019
Stem cell-associated heterogeneity in Glioblastoma results from intrinsic tumor plasticity shaped by the microenvironment.
    Nature communications, 2019, 04-16, Volume: 10, Issue:1

    Topics: Animals; Antineoplastic Agents, Alkylating; Biopsy; Brain Neoplasms; Cell Line, Tumor; Cell Plastici

2019
Estrogen receptor beta enhances chemotherapy response of GBM cells by down regulating DNA damage response pathways.
    Scientific reports, 2019, 04-16, Volume: 9, Issue:1

    Topics: Animals; Antineoplastic Agents, Alkylating; Apoptosis; Ataxia Telangiectasia Mutated Proteins; Brain

2019
Estrogen receptor beta enhances chemotherapy response of GBM cells by down regulating DNA damage response pathways.
    Scientific reports, 2019, 04-16, Volume: 9, Issue:1

    Topics: Animals; Antineoplastic Agents, Alkylating; Apoptosis; Ataxia Telangiectasia Mutated Proteins; Brain

2019
Estrogen receptor beta enhances chemotherapy response of GBM cells by down regulating DNA damage response pathways.
    Scientific reports, 2019, 04-16, Volume: 9, Issue:1

    Topics: Animals; Antineoplastic Agents, Alkylating; Apoptosis; Ataxia Telangiectasia Mutated Proteins; Brain

2019
Genome-Wide CRISPR-Cas9 Screens Expose Genetic Vulnerabilities and Mechanisms of Temozolomide Sensitivity in Glioblastoma Stem Cells.
    Cell reports, 2019, 04-16, Volume: 27, Issue:3

    Topics: Animals; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; CRISPR-Cas Systems; Drug Resistance,

2019
Genome-Wide CRISPR-Cas9 Screens Expose Genetic Vulnerabilities and Mechanisms of Temozolomide Sensitivity in Glioblastoma Stem Cells.
    Cell reports, 2019, 04-16, Volume: 27, Issue:3

    Topics: Animals; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; CRISPR-Cas Systems; Drug Resistance,

2019
Genome-Wide CRISPR-Cas9 Screens Expose Genetic Vulnerabilities and Mechanisms of Temozolomide Sensitivity in Glioblastoma Stem Cells.
    Cell reports, 2019, 04-16, Volume: 27, Issue:3

    Topics: Animals; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; CRISPR-Cas Systems; Drug Resistance,

2019
In vitro and in vivo Study on Glioma Treatment Enhancement by Combining Temozolomide with Calycosin and Formononetin.
    Journal of ethnopharmacology, 2019, Oct-05, Volume: 242

    Topics: Animals; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Brain Ne

2019
In vitro and in vivo Study on Glioma Treatment Enhancement by Combining Temozolomide with Calycosin and Formononetin.
    Journal of ethnopharmacology, 2019, Oct-05, Volume: 242

    Topics: Animals; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Brain Ne

2019
In vitro and in vivo Study on Glioma Treatment Enhancement by Combining Temozolomide with Calycosin and Formononetin.
    Journal of ethnopharmacology, 2019, Oct-05, Volume: 242

    Topics: Animals; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Brain Ne

2019
Role of multidimensional assessment of frailty in predicting outcomes in older patients with glioblastoma treated with adjuvant concurrent chemo-radiation.
    Journal of geriatric oncology, 2019, Volume: 10, Issue:5

    Topics: Age Factors; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy, Adjuvant;

2019
Role of multidimensional assessment of frailty in predicting outcomes in older patients with glioblastoma treated with adjuvant concurrent chemo-radiation.
    Journal of geriatric oncology, 2019, Volume: 10, Issue:5

    Topics: Age Factors; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy, Adjuvant;

2019
Role of multidimensional assessment of frailty in predicting outcomes in older patients with glioblastoma treated with adjuvant concurrent chemo-radiation.
    Journal of geriatric oncology, 2019, Volume: 10, Issue:5

    Topics: Age Factors; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy, Adjuvant;

2019
Furanodienone overcomes temozolomide resistance in glioblastoma through the downregulation of CSPG4-Akt-ERK signalling by inhibiting EGR1-dependent transcription.
    Phytotherapy research : PTR, 2019, Volume: 33, Issue:6

    Topics: Adult; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cell Survival; Chondroitin Sulfate Proteoglycan

2019
Furanodienone overcomes temozolomide resistance in glioblastoma through the downregulation of CSPG4-Akt-ERK signalling by inhibiting EGR1-dependent transcription.
    Phytotherapy research : PTR, 2019, Volume: 33, Issue:6

    Topics: Adult; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cell Survival; Chondroitin Sulfate Proteoglycan

2019
Furanodienone overcomes temozolomide resistance in glioblastoma through the downregulation of CSPG4-Akt-ERK signalling by inhibiting EGR1-dependent transcription.
    Phytotherapy research : PTR, 2019, Volume: 33, Issue:6

    Topics: Adult; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cell Survival; Chondroitin Sulfate Proteoglycan

2019
Provocative Question: Should Ketogenic Metabolic Therapy Become the Standard of Care for Glioblastoma?
    Neurochemical research, 2019, Volume: 44, Issue:10

    Topics: Brain Neoplasms; Glioblastoma; Glucose; Glutamine; Humans; Ketone Bodies; Mitochondria; Standard of

2019
Provocative Question: Should Ketogenic Metabolic Therapy Become the Standard of Care for Glioblastoma?
    Neurochemical research, 2019, Volume: 44, Issue:10

    Topics: Brain Neoplasms; Glioblastoma; Glucose; Glutamine; Humans; Ketone Bodies; Mitochondria; Standard of

2019
Provocative Question: Should Ketogenic Metabolic Therapy Become the Standard of Care for Glioblastoma?
    Neurochemical research, 2019, Volume: 44, Issue:10

    Topics: Brain Neoplasms; Glioblastoma; Glucose; Glutamine; Humans; Ketone Bodies; Mitochondria; Standard of

2019
Pattern of failure in anaplastic glioma patients with an IDH1/2 mutation.
    Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 2020, Volume: 196, Issue:1

    Topics: Adult; Astrocytoma; Brain Neoplasms; Combined Modality Therapy; DNA Mutational Analysis; Female; Fol

2020
Pattern of failure in anaplastic glioma patients with an IDH1/2 mutation.
    Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 2020, Volume: 196, Issue:1

    Topics: Adult; Astrocytoma; Brain Neoplasms; Combined Modality Therapy; DNA Mutational Analysis; Female; Fol

2020
Pattern of failure in anaplastic glioma patients with an IDH1/2 mutation.
    Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 2020, Volume: 196, Issue:1

    Topics: Adult; Astrocytoma; Brain Neoplasms; Combined Modality Therapy; DNA Mutational Analysis; Female; Fol

2020
The efficacy of a coordinated pharmacological blockade in glioblastoma stem cells with nine repurposed drugs using the CUSP9 strategy.
    Journal of cancer research and clinical oncology, 2019, Volume: 145, Issue:6

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Aprepitant; Auranofin; Brain Neoplasms; Cap

2019
The efficacy of a coordinated pharmacological blockade in glioblastoma stem cells with nine repurposed drugs using the CUSP9 strategy.
    Journal of cancer research and clinical oncology, 2019, Volume: 145, Issue:6

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Aprepitant; Auranofin; Brain Neoplasms; Cap

2019
The efficacy of a coordinated pharmacological blockade in glioblastoma stem cells with nine repurposed drugs using the CUSP9 strategy.
    Journal of cancer research and clinical oncology, 2019, Volume: 145, Issue:6

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Aprepitant; Auranofin; Brain Neoplasms; Cap

2019
Bioengineered scaffolds for 3D culture demonstrate extracellular matrix-mediated mechanisms of chemotherapy resistance in glioblastoma.
    Matrix biology : journal of the International Society for Matrix Biology, 2020, Volume: 85-86

    Topics: Brain Neoplasms; Cell Line, Tumor; Cell Movement; Cell Proliferation; Drug Resistance, Neoplasm; Ext

2020
Bioengineered scaffolds for 3D culture demonstrate extracellular matrix-mediated mechanisms of chemotherapy resistance in glioblastoma.
    Matrix biology : journal of the International Society for Matrix Biology, 2020, Volume: 85-86

    Topics: Brain Neoplasms; Cell Line, Tumor; Cell Movement; Cell Proliferation; Drug Resistance, Neoplasm; Ext

2020
Bioengineered scaffolds for 3D culture demonstrate extracellular matrix-mediated mechanisms of chemotherapy resistance in glioblastoma.
    Matrix biology : journal of the International Society for Matrix Biology, 2020, Volume: 85-86

    Topics: Brain Neoplasms; Cell Line, Tumor; Cell Movement; Cell Proliferation; Drug Resistance, Neoplasm; Ext

2020
R406 elicits anti-Warburg effect via Syk-dependent and -independent mechanisms to trigger apoptosis in glioma stem cells.
    Cell death & disease, 2019, 05-01, Volume: 10, Issue:5

    Topics: Animals; Antineoplastic Agents; Apoptosis; Brain Neoplasms; Cell Adhesion; Drug Resistance, Neoplasm

2019
R406 elicits anti-Warburg effect via Syk-dependent and -independent mechanisms to trigger apoptosis in glioma stem cells.
    Cell death & disease, 2019, 05-01, Volume: 10, Issue:5

    Topics: Animals; Antineoplastic Agents; Apoptosis; Brain Neoplasms; Cell Adhesion; Drug Resistance, Neoplasm

2019
R406 elicits anti-Warburg effect via Syk-dependent and -independent mechanisms to trigger apoptosis in glioma stem cells.
    Cell death & disease, 2019, 05-01, Volume: 10, Issue:5

    Topics: Animals; Antineoplastic Agents; Apoptosis; Brain Neoplasms; Cell Adhesion; Drug Resistance, Neoplasm

2019
Inhibition of cyclin E1 overcomes temozolomide resistance in glioblastoma by Mcl-1 degradation.
    Molecular carcinogenesis, 2019, Volume: 58, Issue:8

    Topics: Animals; Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cell Cycle Checkpoints; Cell

2019
Inhibition of cyclin E1 overcomes temozolomide resistance in glioblastoma by Mcl-1 degradation.
    Molecular carcinogenesis, 2019, Volume: 58, Issue:8

    Topics: Animals; Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cell Cycle Checkpoints; Cell

2019
Inhibition of cyclin E1 overcomes temozolomide resistance in glioblastoma by Mcl-1 degradation.
    Molecular carcinogenesis, 2019, Volume: 58, Issue:8

    Topics: Animals; Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cell Cycle Checkpoints; Cell

2019
Synergistic Suppression of Glioblastoma Cell Growth by Combined Application of Temozolomide and Dopamine D2 Receptor Antagonists.
    World neurosurgery, 2019, Volume: 128

    Topics: Animals; Antineoplastic Agents, Alkylating; Autophagy; Brain Neoplasms; Cell Line, Tumor; Cell Proli

2019
Synergistic Suppression of Glioblastoma Cell Growth by Combined Application of Temozolomide and Dopamine D2 Receptor Antagonists.
    World neurosurgery, 2019, Volume: 128

    Topics: Animals; Antineoplastic Agents, Alkylating; Autophagy; Brain Neoplasms; Cell Line, Tumor; Cell Proli

2019
Synergistic Suppression of Glioblastoma Cell Growth by Combined Application of Temozolomide and Dopamine D2 Receptor Antagonists.
    World neurosurgery, 2019, Volume: 128

    Topics: Animals; Antineoplastic Agents, Alkylating; Autophagy; Brain Neoplasms; Cell Line, Tumor; Cell Proli

2019
Lnc-TALC promotes O
    Nature communications, 2019, 05-03, Volume: 10, Issue:1

    Topics: Adult; Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; DNA Modificati

2019
Lnc-TALC promotes O
    Nature communications, 2019, 05-03, Volume: 10, Issue:1

    Topics: Adult; Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; DNA Modificati

2019
Lnc-TALC promotes O
    Nature communications, 2019, 05-03, Volume: 10, Issue:1

    Topics: Adult; Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; DNA Modificati

2019
Downregulation of miR‑186 promotes the proliferation and drug resistance of glioblastoma cells by targeting Twist1.
    Molecular medicine reports, 2019, Volume: 19, Issue:6

    Topics: 3' Untranslated Regions; Adult; Aged; Antagomirs; Brain Neoplasms; Case-Control Studies; Cell Line,

2019
Downregulation of miR‑186 promotes the proliferation and drug resistance of glioblastoma cells by targeting Twist1.
    Molecular medicine reports, 2019, Volume: 19, Issue:6

    Topics: 3' Untranslated Regions; Adult; Aged; Antagomirs; Brain Neoplasms; Case-Control Studies; Cell Line,

2019
Downregulation of miR‑186 promotes the proliferation and drug resistance of glioblastoma cells by targeting Twist1.
    Molecular medicine reports, 2019, Volume: 19, Issue:6

    Topics: 3' Untranslated Regions; Adult; Aged; Antagomirs; Brain Neoplasms; Case-Control Studies; Cell Line,

2019
Pam
    Investigational new drugs, 2020, Volume: 38, Issue:2

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Differentiation; Cell Line, Tumor; Cell Sur

2020
Pam
    Investigational new drugs, 2020, Volume: 38, Issue:2

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Differentiation; Cell Line, Tumor; Cell Sur

2020
Pam
    Investigational new drugs, 2020, Volume: 38, Issue:2

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Differentiation; Cell Line, Tumor; Cell Sur

2020
Targeted therapy based on p53 reactivation reduces both glioblastoma cell growth and resistance to temozolomide.
    International journal of oncology, 2019, Volume: 54, Issue:6

    Topics: Brain Neoplasms; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cell Survival; Drug Resistance, N

2019
Targeted therapy based on p53 reactivation reduces both glioblastoma cell growth and resistance to temozolomide.
    International journal of oncology, 2019, Volume: 54, Issue:6

    Topics: Brain Neoplasms; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cell Survival; Drug Resistance, N

2019
Targeted therapy based on p53 reactivation reduces both glioblastoma cell growth and resistance to temozolomide.
    International journal of oncology, 2019, Volume: 54, Issue:6

    Topics: Brain Neoplasms; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cell Survival; Drug Resistance, N

2019
Novel predictive epigenetic signature for temozolomide in non-G-CIMP glioblastomas.
    Clinical epigenetics, 2019, 05-14, Volume: 11, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Cell Survi

2019
Novel predictive epigenetic signature for temozolomide in non-G-CIMP glioblastomas.
    Clinical epigenetics, 2019, 05-14, Volume: 11, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Cell Survi

2019
Novel predictive epigenetic signature for temozolomide in non-G-CIMP glioblastomas.
    Clinical epigenetics, 2019, 05-14, Volume: 11, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Cell Survi

2019
Identification of SEC61G as a Novel Prognostic Marker for Predicting Survival and Response to Therapies in Patients with Glioblastoma.
    Medical science monitor : international medical journal of experimental and clinical research, 2019, May-16, Volume: 25

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Biomarkers, Tumor; Brain Neoplasm

2019
Identification of SEC61G as a Novel Prognostic Marker for Predicting Survival and Response to Therapies in Patients with Glioblastoma.
    Medical science monitor : international medical journal of experimental and clinical research, 2019, May-16, Volume: 25

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Biomarkers, Tumor; Brain Neoplasm

2019
Identification of SEC61G as a Novel Prognostic Marker for Predicting Survival and Response to Therapies in Patients with Glioblastoma.
    Medical science monitor : international medical journal of experimental and clinical research, 2019, May-16, Volume: 25

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Biomarkers, Tumor; Brain Neoplasm

2019
Susceptibility and Tumor Size Changes During the Time Course of Standard Treatment in Recurrent Glioblastoma.
    Journal of neuroimaging : official journal of the American Society of Neuroimaging, 2019, Volume: 29, Issue:5

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Disease Progression; Female; Gliobl

2019
Susceptibility and Tumor Size Changes During the Time Course of Standard Treatment in Recurrent Glioblastoma.
    Journal of neuroimaging : official journal of the American Society of Neuroimaging, 2019, Volume: 29, Issue:5

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Disease Progression; Female; Gliobl

2019
Susceptibility and Tumor Size Changes During the Time Course of Standard Treatment in Recurrent Glioblastoma.
    Journal of neuroimaging : official journal of the American Society of Neuroimaging, 2019, Volume: 29, Issue:5

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Disease Progression; Female; Gliobl

2019
Xenograft-based, platform-independent gene signatures to predict response to alkylating chemotherapy, radiation, and combination therapy for glioblastoma.
    Neuro-oncology, 2019, 09-06, Volume: 21, Issue:9

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherap

2019
Xenograft-based, platform-independent gene signatures to predict response to alkylating chemotherapy, radiation, and combination therapy for glioblastoma.
    Neuro-oncology, 2019, 09-06, Volume: 21, Issue:9

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherap

2019
Xenograft-based, platform-independent gene signatures to predict response to alkylating chemotherapy, radiation, and combination therapy for glioblastoma.
    Neuro-oncology, 2019, 09-06, Volume: 21, Issue:9

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherap

2019
RETRACTED: IP1867B suppresses the insulin-like growth factor 1 receptor (IGF1R) ablating epidermal growth factor receptor inhibitor resistance in adult high grade gliomas.
    Cancer letters, 2019, 08-28, Volume: 458

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Aspirin; Brain Neoplasms; Cell Hypoxia; Dru

2019
RETRACTED: IP1867B suppresses the insulin-like growth factor 1 receptor (IGF1R) ablating epidermal growth factor receptor inhibitor resistance in adult high grade gliomas.
    Cancer letters, 2019, 08-28, Volume: 458

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Aspirin; Brain Neoplasms; Cell Hypoxia; Dru

2019
RETRACTED: IP1867B suppresses the insulin-like growth factor 1 receptor (IGF1R) ablating epidermal growth factor receptor inhibitor resistance in adult high grade gliomas.
    Cancer letters, 2019, 08-28, Volume: 458

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Aspirin; Brain Neoplasms; Cell Hypoxia; Dru

2019
Survival trends in glioblastoma and association with treating facility volume.
    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2019, Volume: 68

    Topics: Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Databases, Fact

2019
Survival trends in glioblastoma and association with treating facility volume.
    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2019, Volume: 68

    Topics: Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Databases, Fact

2019
Survival trends in glioblastoma and association with treating facility volume.
    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2019, Volume: 68

    Topics: Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Databases, Fact

2019
A bioprinted human-glioblastoma-on-a-chip for the identification of patient-specific responses to chemoradiotherapy.
    Nature biomedical engineering, 2019, Volume: 3, Issue:7

    Topics: Bioprinting; Brain; Brain Neoplasms; Cell Line, Tumor; Chemoradiotherapy; Drug Combinations; Drug Ev

2019
A bioprinted human-glioblastoma-on-a-chip for the identification of patient-specific responses to chemoradiotherapy.
    Nature biomedical engineering, 2019, Volume: 3, Issue:7

    Topics: Bioprinting; Brain; Brain Neoplasms; Cell Line, Tumor; Chemoradiotherapy; Drug Combinations; Drug Ev

2019
A bioprinted human-glioblastoma-on-a-chip for the identification of patient-specific responses to chemoradiotherapy.
    Nature biomedical engineering, 2019, Volume: 3, Issue:7

    Topics: Bioprinting; Brain; Brain Neoplasms; Cell Line, Tumor; Chemoradiotherapy; Drug Combinations; Drug Ev

2019
Cerebral aspergillosis within new tumour site presents as incidental new brain lesion in patient receiving temozolomide for glioblastoma multiforme.
    BMJ case reports, 2019, May-31, Volume: 12, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Aspergillosis; Brain Abscess; Brain Neoplasms; Combined Modality

2019
Cerebral aspergillosis within new tumour site presents as incidental new brain lesion in patient receiving temozolomide for glioblastoma multiforme.
    BMJ case reports, 2019, May-31, Volume: 12, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Aspergillosis; Brain Abscess; Brain Neoplasms; Combined Modality

2019
Cerebral aspergillosis within new tumour site presents as incidental new brain lesion in patient receiving temozolomide for glioblastoma multiforme.
    BMJ case reports, 2019, May-31, Volume: 12, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Aspergillosis; Brain Abscess; Brain Neoplasms; Combined Modality

2019
Oleuropein modulates glioblastoma miRNA pattern different from
    Human & experimental toxicology, 2019, Volume: 38, Issue:9

    Topics: Antineoplastic Agents, Alkylating; Antineoplastic Agents, Phytogenic; Brain Neoplasms; Cell Line, Tu

2019
Oleuropein modulates glioblastoma miRNA pattern different from
    Human & experimental toxicology, 2019, Volume: 38, Issue:9

    Topics: Antineoplastic Agents, Alkylating; Antineoplastic Agents, Phytogenic; Brain Neoplasms; Cell Line, Tu

2019
Oleuropein modulates glioblastoma miRNA pattern different from
    Human & experimental toxicology, 2019, Volume: 38, Issue:9

    Topics: Antineoplastic Agents, Alkylating; Antineoplastic Agents, Phytogenic; Brain Neoplasms; Cell Line, Tu

2019
Super-early initiation of temozolomide prolongs the survival of glioblastoma patients without gross-total resection: a retrospective cohort study.
    Journal of neuro-oncology, 2019, Volume: 144, Issue:1

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Female; Follow-Up Studi

2019
Super-early initiation of temozolomide prolongs the survival of glioblastoma patients without gross-total resection: a retrospective cohort study.
    Journal of neuro-oncology, 2019, Volume: 144, Issue:1

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Female; Follow-Up Studi

2019
Super-early initiation of temozolomide prolongs the survival of glioblastoma patients without gross-total resection: a retrospective cohort study.
    Journal of neuro-oncology, 2019, Volume: 144, Issue:1

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Female; Follow-Up Studi

2019
Bufothionine Promotes Apoptosis via Triggering ER Stress and Synergizes with Temozolomide in Glioblastoma Multiforme Cells.
    Anatomical record (Hoboken, N.J. : 2007), 2019, Volume: 302, Issue:11

    Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Brain Neoplasms; Cell Proliferation; Drug

2019
Bufothionine Promotes Apoptosis via Triggering ER Stress and Synergizes with Temozolomide in Glioblastoma Multiforme Cells.
    Anatomical record (Hoboken, N.J. : 2007), 2019, Volume: 302, Issue:11

    Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Brain Neoplasms; Cell Proliferation; Drug

2019
Bufothionine Promotes Apoptosis via Triggering ER Stress and Synergizes with Temozolomide in Glioblastoma Multiforme Cells.
    Anatomical record (Hoboken, N.J. : 2007), 2019, Volume: 302, Issue:11

    Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Brain Neoplasms; Cell Proliferation; Drug

2019
Inhibition of Metabolic Shift can Decrease Therapy Resistance in Human High-Grade Glioma Cells.
    Pathology oncology research : POR, 2020, Volume: 26, Issue:1

    Topics: Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Drug Resistance, Neoplasm; Drug Synergism; En

2020
Inhibition of Metabolic Shift can Decrease Therapy Resistance in Human High-Grade Glioma Cells.
    Pathology oncology research : POR, 2020, Volume: 26, Issue:1

    Topics: Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Drug Resistance, Neoplasm; Drug Synergism; En

2020
Inhibition of Metabolic Shift can Decrease Therapy Resistance in Human High-Grade Glioma Cells.
    Pathology oncology research : POR, 2020, Volume: 26, Issue:1

    Topics: Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Drug Resistance, Neoplasm; Drug Synergism; En

2020
Angiopep-2 Modified Cationic Lipid-Poly-Lactic-Co-Glycolic Acid Delivery Temozolomide and DNA Repair Inhibitor Dbait to Achieve Synergetic Chemo-Radiotherapy Against Glioma.
    Journal of nanoscience and nanotechnology, 2019, 12-01, Volume: 19, Issue:12

    Topics: Brain Neoplasms; Cell Line, Tumor; Chemoradiotherapy; DNA Repair; Glioblastoma; Glioma; Glycolates;

2019
Angiopep-2 Modified Cationic Lipid-Poly-Lactic-Co-Glycolic Acid Delivery Temozolomide and DNA Repair Inhibitor Dbait to Achieve Synergetic Chemo-Radiotherapy Against Glioma.
    Journal of nanoscience and nanotechnology, 2019, 12-01, Volume: 19, Issue:12

    Topics: Brain Neoplasms; Cell Line, Tumor; Chemoradiotherapy; DNA Repair; Glioblastoma; Glioma; Glycolates;

2019
Angiopep-2 Modified Cationic Lipid-Poly-Lactic-Co-Glycolic Acid Delivery Temozolomide and DNA Repair Inhibitor Dbait to Achieve Synergetic Chemo-Radiotherapy Against Glioma.
    Journal of nanoscience and nanotechnology, 2019, 12-01, Volume: 19, Issue:12

    Topics: Brain Neoplasms; Cell Line, Tumor; Chemoradiotherapy; DNA Repair; Glioblastoma; Glioma; Glycolates;

2019
    Journal of biomedical nanotechnology, 2019, 07-01, Volume: 15, Issue:7

    Topics: Adult; Brain Neoplasms; Cell Line, Tumor; Dacarbazine; Glioblastoma; Humans; Neoplastic Stem Cells;

2019
    Journal of biomedical nanotechnology, 2019, 07-01, Volume: 15, Issue:7

    Topics: Adult; Brain Neoplasms; Cell Line, Tumor; Dacarbazine; Glioblastoma; Humans; Neoplastic Stem Cells;

2019
    Journal of biomedical nanotechnology, 2019, 07-01, Volume: 15, Issue:7

    Topics: Adult; Brain Neoplasms; Cell Line, Tumor; Dacarbazine; Glioblastoma; Humans; Neoplastic Stem Cells;

2019
Afatinib and Temozolomide combination inhibits tumorigenesis by targeting EGFRvIII-cMet signaling in glioblastoma cells.
    Journal of experimental & clinical cancer research : CR, 2019, Jun-18, Volume: 38, Issue:1

    Topics: Afatinib; Animals; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Cell Line, Tumor

2019
Afatinib and Temozolomide combination inhibits tumorigenesis by targeting EGFRvIII-cMet signaling in glioblastoma cells.
    Journal of experimental & clinical cancer research : CR, 2019, Jun-18, Volume: 38, Issue:1

    Topics: Afatinib; Animals; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Cell Line, Tumor

2019
Afatinib and Temozolomide combination inhibits tumorigenesis by targeting EGFRvIII-cMet signaling in glioblastoma cells.
    Journal of experimental & clinical cancer research : CR, 2019, Jun-18, Volume: 38, Issue:1

    Topics: Afatinib; Animals; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Cell Line, Tumor

2019
microRNA-181d associated with the methylation status of the MGMT gene in Glioblastoma multiforme cancer stem cells submitted to treatments with ionizing radiation and temozolomide.
    Brain research, 2019, 10-01, Volume: 1720

    Topics: Aged; Aged, 80 and over; Biomarkers, Tumor; Brain Neoplasms; Brazil; DNA Methylation; DNA Modificati

2019
microRNA-181d associated with the methylation status of the MGMT gene in Glioblastoma multiforme cancer stem cells submitted to treatments with ionizing radiation and temozolomide.
    Brain research, 2019, 10-01, Volume: 1720

    Topics: Aged; Aged, 80 and over; Biomarkers, Tumor; Brain Neoplasms; Brazil; DNA Methylation; DNA Modificati

2019
microRNA-181d associated with the methylation status of the MGMT gene in Glioblastoma multiforme cancer stem cells submitted to treatments with ionizing radiation and temozolomide.
    Brain research, 2019, 10-01, Volume: 1720

    Topics: Aged; Aged, 80 and over; Biomarkers, Tumor; Brain Neoplasms; Brazil; DNA Methylation; DNA Modificati

2019
MPC1 deletion is associated with poor prognosis and temozolomide resistance in glioblastoma.
    Journal of neuro-oncology, 2019, Volume: 144, Issue:2

    Topics: Antineoplastic Agents, Alkylating; Biomarkers, Tumor; Brain Neoplasms; Drug Resistance, Neoplasm; Fe

2019
MPC1 deletion is associated with poor prognosis and temozolomide resistance in glioblastoma.
    Journal of neuro-oncology, 2019, Volume: 144, Issue:2

    Topics: Antineoplastic Agents, Alkylating; Biomarkers, Tumor; Brain Neoplasms; Drug Resistance, Neoplasm; Fe

2019
MPC1 deletion is associated with poor prognosis and temozolomide resistance in glioblastoma.
    Journal of neuro-oncology, 2019, Volume: 144, Issue:2

    Topics: Antineoplastic Agents, Alkylating; Biomarkers, Tumor; Brain Neoplasms; Drug Resistance, Neoplasm; Fe

2019
Human organotypic brain slice culture: a novel framework for environmental research in neuro-oncology.
    Life science alliance, 2019, Volume: 2, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Astrocytes; Brain; Brain Neoplasms; Cell Movement; Cell Proliferatio

2019
Human organotypic brain slice culture: a novel framework for environmental research in neuro-oncology.
    Life science alliance, 2019, Volume: 2, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Astrocytes; Brain; Brain Neoplasms; Cell Movement; Cell Proliferatio

2019
Human organotypic brain slice culture: a novel framework for environmental research in neuro-oncology.
    Life science alliance, 2019, Volume: 2, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Astrocytes; Brain; Brain Neoplasms; Cell Movement; Cell Proliferatio

2019
Temozolomide-induced aplastic anaemia and incidental low-grade B-cell non-Hodgkin lymphoma in a geriatric patient with glioblastoma multiforme.
    BMJ case reports, 2019, Jun-29, Volume: 12, Issue:6

    Topics: Aged, 80 and over; Anemia, Aplastic; Antineoplastic Agents, Alkylating; Brain; Brain Neoplasms; Fata

2019
Temozolomide-induced aplastic anaemia and incidental low-grade B-cell non-Hodgkin lymphoma in a geriatric patient with glioblastoma multiforme.
    BMJ case reports, 2019, Jun-29, Volume: 12, Issue:6

    Topics: Aged, 80 and over; Anemia, Aplastic; Antineoplastic Agents, Alkylating; Brain; Brain Neoplasms; Fata

2019
Temozolomide-induced aplastic anaemia and incidental low-grade B-cell non-Hodgkin lymphoma in a geriatric patient with glioblastoma multiforme.
    BMJ case reports, 2019, Jun-29, Volume: 12, Issue:6

    Topics: Aged, 80 and over; Anemia, Aplastic; Antineoplastic Agents, Alkylating; Brain; Brain Neoplasms; Fata

2019
Ultrasmall theranostic gadolinium-based nanoparticles improve high-grade rat glioma survival.
    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2019, Volume: 67

    Topics: Animals; Brain Neoplasms; Chemoradiotherapy; Contrast Media; Gadolinium; Glioma; Magnetic Resonance

2019
Ultrasmall theranostic gadolinium-based nanoparticles improve high-grade rat glioma survival.
    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2019, Volume: 67

    Topics: Animals; Brain Neoplasms; Chemoradiotherapy; Contrast Media; Gadolinium; Glioma; Magnetic Resonance

2019
Ultrasmall theranostic gadolinium-based nanoparticles improve high-grade rat glioma survival.
    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2019, Volume: 67

    Topics: Animals; Brain Neoplasms; Chemoradiotherapy; Contrast Media; Gadolinium; Glioma; Magnetic Resonance

2019
The Prognostic Value of the Pretreatment Neutrophil/Lymphocyte Ratio in Patients with Glioblastoma Multiforme Brain Tumors: A Retrospective Cohort Study of Patients Treated with Combined Modality Surgery, Radiation Therapy, and Temozolomide Chemotherapy.
    Oncology, 2019, Volume: 97, Issue:5

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Brain Neoplasms; Combined Modality Therapy; Female; Glio

2019
The Prognostic Value of the Pretreatment Neutrophil/Lymphocyte Ratio in Patients with Glioblastoma Multiforme Brain Tumors: A Retrospective Cohort Study of Patients Treated with Combined Modality Surgery, Radiation Therapy, and Temozolomide Chemotherapy.
    Oncology, 2019, Volume: 97, Issue:5

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Brain Neoplasms; Combined Modality Therapy; Female; Glio

2019
The Prognostic Value of the Pretreatment Neutrophil/Lymphocyte Ratio in Patients with Glioblastoma Multiforme Brain Tumors: A Retrospective Cohort Study of Patients Treated with Combined Modality Surgery, Radiation Therapy, and Temozolomide Chemotherapy.
    Oncology, 2019, Volume: 97, Issue:5

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Brain Neoplasms; Combined Modality Therapy; Female; Glio

2019
ID1 Is Critical for Tumorigenesis and Regulates Chemoresistance in Glioblastoma.
    Cancer research, 2019, 08-15, Volume: 79, Issue:16

    Topics: Animals; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Brain Ne

2019
ID1 Is Critical for Tumorigenesis and Regulates Chemoresistance in Glioblastoma.
    Cancer research, 2019, 08-15, Volume: 79, Issue:16

    Topics: Animals; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Brain Ne

2019
ID1 Is Critical for Tumorigenesis and Regulates Chemoresistance in Glioblastoma.
    Cancer research, 2019, 08-15, Volume: 79, Issue:16

    Topics: Animals; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Brain Ne

2019
Identification of GSK3β inhibitor kenpaullone as a temozolomide enhancer against glioblastoma.
    Scientific reports, 2019, 07-11, Volume: 9, Issue:1

    Topics: Animals; Benzazepines; Brain Neoplasms; Cell Line, Tumor; Cell Survival; Chemotherapy, Adjuvant; Dru

2019
Identification of GSK3β inhibitor kenpaullone as a temozolomide enhancer against glioblastoma.
    Scientific reports, 2019, 07-11, Volume: 9, Issue:1

    Topics: Animals; Benzazepines; Brain Neoplasms; Cell Line, Tumor; Cell Survival; Chemotherapy, Adjuvant; Dru

2019
Identification of GSK3β inhibitor kenpaullone as a temozolomide enhancer against glioblastoma.
    Scientific reports, 2019, 07-11, Volume: 9, Issue:1

    Topics: Animals; Benzazepines; Brain Neoplasms; Cell Line, Tumor; Cell Survival; Chemotherapy, Adjuvant; Dru

2019
Codelivery of paclitaxel and temozolomide through a photopolymerizable hydrogel prevents glioblastoma recurrence after surgical resection.
    Journal of controlled release : official journal of the Controlled Release Society, 2019, 09-10, Volume: 309

    Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Cell Line, Tumor; Drug Combinations; Drug Delivery

2019
Codelivery of paclitaxel and temozolomide through a photopolymerizable hydrogel prevents glioblastoma recurrence after surgical resection.
    Journal of controlled release : official journal of the Controlled Release Society, 2019, 09-10, Volume: 309

    Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Cell Line, Tumor; Drug Combinations; Drug Delivery

2019
Codelivery of paclitaxel and temozolomide through a photopolymerizable hydrogel prevents glioblastoma recurrence after surgical resection.
    Journal of controlled release : official journal of the Controlled Release Society, 2019, 09-10, Volume: 309

    Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Cell Line, Tumor; Drug Combinations; Drug Delivery

2019
Combined elevation of TRIB2 and MAP3K1 indicates poor prognosis and chemoresistance to temozolomide in glioblastoma.
    CNS neuroscience & therapeutics, 2020, Volume: 26, Issue:3

    Topics: Adult; Antineoplastic Agents, Alkylating; Brain Neoplasms; Calcium-Calmodulin-Dependent Protein Kina

2020
Combined elevation of TRIB2 and MAP3K1 indicates poor prognosis and chemoresistance to temozolomide in glioblastoma.
    CNS neuroscience & therapeutics, 2020, Volume: 26, Issue:3

    Topics: Adult; Antineoplastic Agents, Alkylating; Brain Neoplasms; Calcium-Calmodulin-Dependent Protein Kina

2020
Combined elevation of TRIB2 and MAP3K1 indicates poor prognosis and chemoresistance to temozolomide in glioblastoma.
    CNS neuroscience & therapeutics, 2020, Volume: 26, Issue:3

    Topics: Adult; Antineoplastic Agents, Alkylating; Brain Neoplasms; Calcium-Calmodulin-Dependent Protein Kina

2020
Acquired temozolomide resistance in MGMT-deficient glioblastoma cells is associated with regulation of DNA repair by DHC2.
    Brain : a journal of neurology, 2019, 08-01, Volume: 142, Issue:8

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chromobox Protein Homolog 5; Cytoplasmi

2019
Acquired temozolomide resistance in MGMT-deficient glioblastoma cells is associated with regulation of DNA repair by DHC2.
    Brain : a journal of neurology, 2019, 08-01, Volume: 142, Issue:8

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chromobox Protein Homolog 5; Cytoplasmi

2019
Acquired temozolomide resistance in MGMT-deficient glioblastoma cells is associated with regulation of DNA repair by DHC2.
    Brain : a journal of neurology, 2019, 08-01, Volume: 142, Issue:8

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chromobox Protein Homolog 5; Cytoplasmi

2019
Efficacy of EGFR plus TNF inhibition in a preclinical model of temozolomide-resistant glioblastoma.
    Neuro-oncology, 2019, 12-17, Volume: 21, Issue:12

    Topics: Afatinib; Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Brain Neoplasms; Cell

2019
Efficacy of EGFR plus TNF inhibition in a preclinical model of temozolomide-resistant glioblastoma.
    Neuro-oncology, 2019, 12-17, Volume: 21, Issue:12

    Topics: Afatinib; Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Brain Neoplasms; Cell

2019
Efficacy of EGFR plus TNF inhibition in a preclinical model of temozolomide-resistant glioblastoma.
    Neuro-oncology, 2019, 12-17, Volume: 21, Issue:12

    Topics: Afatinib; Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Brain Neoplasms; Cell

2019
Valproic acid-induced amphiregulin secretion confers resistance to temozolomide treatment in human glioma cells.
    BMC cancer, 2019, Aug-01, Volume: 19, Issue:1

    Topics: Amphiregulin; Antibodies, Blocking; Antineoplastic Agents, Alkylating; Biomarkers, Tumor; Brain Neop

2019
Valproic acid-induced amphiregulin secretion confers resistance to temozolomide treatment in human glioma cells.
    BMC cancer, 2019, Aug-01, Volume: 19, Issue:1

    Topics: Amphiregulin; Antibodies, Blocking; Antineoplastic Agents, Alkylating; Biomarkers, Tumor; Brain Neop

2019
Valproic acid-induced amphiregulin secretion confers resistance to temozolomide treatment in human glioma cells.
    BMC cancer, 2019, Aug-01, Volume: 19, Issue:1

    Topics: Amphiregulin; Antibodies, Blocking; Antineoplastic Agents, Alkylating; Biomarkers, Tumor; Brain Neop

2019
Exosomes derived from microRNA-199a-overexpressing mesenchymal stem cells inhibit glioma progression by down-regulating AGAP2.
    Aging, 2019, 08-05, Volume: 11, Issue:15

    Topics: Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cell Movement; Cell

2019
Exosomes derived from microRNA-199a-overexpressing mesenchymal stem cells inhibit glioma progression by down-regulating AGAP2.
    Aging, 2019, 08-05, Volume: 11, Issue:15

    Topics: Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cell Movement; Cell

2019
Exosomes derived from microRNA-199a-overexpressing mesenchymal stem cells inhibit glioma progression by down-regulating AGAP2.
    Aging, 2019, 08-05, Volume: 11, Issue:15

    Topics: Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cell Movement; Cell

2019
MELK-dependent FOXM1 phosphorylation is essential for proliferation of glioma stem cells.
    Stem cells (Dayton, Ohio), 2013, Volume: 31, Issue:6

    Topics: Animals; Brain Neoplasms; Cell Cycle Proteins; Cell Proliferation; Cells, Cultured; Dacarbazine; For

2013
MELK-dependent FOXM1 phosphorylation is essential for proliferation of glioma stem cells.
    Stem cells (Dayton, Ohio), 2013, Volume: 31, Issue:6

    Topics: Animals; Brain Neoplasms; Cell Cycle Proteins; Cell Proliferation; Cells, Cultured; Dacarbazine; For

2013
MELK-dependent FOXM1 phosphorylation is essential for proliferation of glioma stem cells.
    Stem cells (Dayton, Ohio), 2013, Volume: 31, Issue:6

    Topics: Animals; Brain Neoplasms; Cell Cycle Proteins; Cell Proliferation; Cells, Cultured; Dacarbazine; For

2013
Reversing the Warburg effect as a treatment for glioblastoma.
    The Journal of biological chemistry, 2013, Mar-29, Volume: 288, Issue:13

    Topics: Adenosine Triphosphate; Animals; Annexin A5; Antineoplastic Agents; Antineoplastic Agents, Alkylatin

2013
Reversing the Warburg effect as a treatment for glioblastoma.
    The Journal of biological chemistry, 2013, Mar-29, Volume: 288, Issue:13

    Topics: Adenosine Triphosphate; Animals; Annexin A5; Antineoplastic Agents; Antineoplastic Agents, Alkylatin

2013
Reversing the Warburg effect as a treatment for glioblastoma.
    The Journal of biological chemistry, 2013, Mar-29, Volume: 288, Issue:13

    Topics: Adenosine Triphosphate; Animals; Annexin A5; Antineoplastic Agents; Antineoplastic Agents, Alkylatin

2013
Morphologic MRI features, diffusion tensor imaging and radiation dosimetric analysis to differentiate pseudo-progression from early tumor progression.
    Journal of neuro-oncology, 2013, Volume: 112, Issue:3

    Topics: Antineoplastic Agents; Brain Neoplasms; Chemoradiotherapy; Dacarbazine; Diffusion Magnetic Resonance

2013
Morphologic MRI features, diffusion tensor imaging and radiation dosimetric analysis to differentiate pseudo-progression from early tumor progression.
    Journal of neuro-oncology, 2013, Volume: 112, Issue:3

    Topics: Antineoplastic Agents; Brain Neoplasms; Chemoradiotherapy; Dacarbazine; Diffusion Magnetic Resonance

2013
Morphologic MRI features, diffusion tensor imaging and radiation dosimetric analysis to differentiate pseudo-progression from early tumor progression.
    Journal of neuro-oncology, 2013, Volume: 112, Issue:3

    Topics: Antineoplastic Agents; Brain Neoplasms; Chemoradiotherapy; Dacarbazine; Diffusion Magnetic Resonance

2013
The impact of sequential vs. combined radiochemotherapy with temozolomide, resection and MGMT promoter hypermethylation on survival of patients with primary glioblastoma--a single centre retrospective study.
    British journal of neurosurgery, 2013, Volume: 27, Issue:4

    Topics: Antineoplastic Agents, Alkylating; Antineoplastic Protocols; Biomarkers, Tumor; Brain Neoplasms; Che

2013
The impact of sequential vs. combined radiochemotherapy with temozolomide, resection and MGMT promoter hypermethylation on survival of patients with primary glioblastoma--a single centre retrospective study.
    British journal of neurosurgery, 2013, Volume: 27, Issue:4

    Topics: Antineoplastic Agents, Alkylating; Antineoplastic Protocols; Biomarkers, Tumor; Brain Neoplasms; Che

2013
The impact of sequential vs. combined radiochemotherapy with temozolomide, resection and MGMT promoter hypermethylation on survival of patients with primary glioblastoma--a single centre retrospective study.
    British journal of neurosurgery, 2013, Volume: 27, Issue:4

    Topics: Antineoplastic Agents, Alkylating; Antineoplastic Protocols; Biomarkers, Tumor; Brain Neoplasms; Che

2013
Treatment of children with glioblastoma with conformal radiation, temozolomide, and bevacizumab as adjuncts to surgical resection.
    Journal of pediatric hematology/oncology, 2013, Volume: 35, Issue:3

    Topics: Adolescent; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Bevac

2013
Treatment of children with glioblastoma with conformal radiation, temozolomide, and bevacizumab as adjuncts to surgical resection.
    Journal of pediatric hematology/oncology, 2013, Volume: 35, Issue:3

    Topics: Adolescent; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Bevac

2013
Treatment of children with glioblastoma with conformal radiation, temozolomide, and bevacizumab as adjuncts to surgical resection.
    Journal of pediatric hematology/oncology, 2013, Volume: 35, Issue:3

    Topics: Adolescent; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Bevac

2013
Bilateral ptosis as initial presentation of gliomatosis cerebri: case report.
    Journal of neurological surgery. Part A, Central European neurosurgery, 2013, Volume: 74 Suppl 1

    Topics: Anticonvulsants; Antineoplastic Agents, Alkylating; Blepharoptosis; Brain Neoplasms; Chemoradiothera

2013
Bilateral ptosis as initial presentation of gliomatosis cerebri: case report.
    Journal of neurological surgery. Part A, Central European neurosurgery, 2013, Volume: 74 Suppl 1

    Topics: Anticonvulsants; Antineoplastic Agents, Alkylating; Blepharoptosis; Brain Neoplasms; Chemoradiothera

2013
Bilateral ptosis as initial presentation of gliomatosis cerebri: case report.
    Journal of neurological surgery. Part A, Central European neurosurgery, 2013, Volume: 74 Suppl 1

    Topics: Anticonvulsants; Antineoplastic Agents, Alkylating; Blepharoptosis; Brain Neoplasms; Chemoradiothera

2013
Prognostic factors for overall survival after radiosurgery for brain metastases from melanoma.
    American journal of clinical oncology, 2014, Volume: 37, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cohort Studies;

2014
Prognostic factors for overall survival after radiosurgery for brain metastases from melanoma.
    American journal of clinical oncology, 2014, Volume: 37, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cohort Studies;

2014
Prognostic factors for overall survival after radiosurgery for brain metastases from melanoma.
    American journal of clinical oncology, 2014, Volume: 37, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cohort Studies;

2014
Inhibition of prolyl 4-hydroxylase, beta polypeptide (P4HB) attenuates temozolomide resistance in malignant glioma via the endoplasmic reticulum stress response (ERSR) pathways.
    Neuro-oncology, 2013, Volume: 15, Issue:5

    Topics: Animals; Antineoplastic Agents, Alkylating; Apoptosis; Blotting, Western; Brain Neoplasms; Cell Prol

2013
Inhibition of prolyl 4-hydroxylase, beta polypeptide (P4HB) attenuates temozolomide resistance in malignant glioma via the endoplasmic reticulum stress response (ERSR) pathways.
    Neuro-oncology, 2013, Volume: 15, Issue:5

    Topics: Animals; Antineoplastic Agents, Alkylating; Apoptosis; Blotting, Western; Brain Neoplasms; Cell Prol

2013
Inhibition of prolyl 4-hydroxylase, beta polypeptide (P4HB) attenuates temozolomide resistance in malignant glioma via the endoplasmic reticulum stress response (ERSR) pathways.
    Neuro-oncology, 2013, Volume: 15, Issue:5

    Topics: Animals; Antineoplastic Agents, Alkylating; Apoptosis; Blotting, Western; Brain Neoplasms; Cell Prol

2013
Patterns of care and outcome for patients with glioblastoma diagnosed during 2008-2010 in Spain.
    Neuro-oncology, 2013, Volume: 15, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modalit

2013
Patterns of care and outcome for patients with glioblastoma diagnosed during 2008-2010 in Spain.
    Neuro-oncology, 2013, Volume: 15, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modalit

2013
Patterns of care and outcome for patients with glioblastoma diagnosed during 2008-2010 in Spain.
    Neuro-oncology, 2013, Volume: 15, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modalit

2013
Steroid management in newly diagnosed glioblastoma.
    Journal of neuro-oncology, 2013, Volume: 113, Issue:1

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Dacarbazine; Fem

2013
Steroid management in newly diagnosed glioblastoma.
    Journal of neuro-oncology, 2013, Volume: 113, Issue:1

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Dacarbazine; Fem

2013
Steroid management in newly diagnosed glioblastoma.
    Journal of neuro-oncology, 2013, Volume: 113, Issue:1

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Dacarbazine; Fem

2013
Neoadjuvant chemotherapy may optimize the extent of resection of World Health Organization grade II gliomas: a case series of 17 patients.
    Journal of neuro-oncology, 2013, Volume: 113, Issue:2

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Biomarkers, Tumor; Brain Neoplasms; Comb

2013
Neoadjuvant chemotherapy may optimize the extent of resection of World Health Organization grade II gliomas: a case series of 17 patients.
    Journal of neuro-oncology, 2013, Volume: 113, Issue:2

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Biomarkers, Tumor; Brain Neoplasms; Comb

2013
Neoadjuvant chemotherapy may optimize the extent of resection of World Health Organization grade II gliomas: a case series of 17 patients.
    Journal of neuro-oncology, 2013, Volume: 113, Issue:2

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Biomarkers, Tumor; Brain Neoplasms; Comb

2013
Efficacy of protracted temozolomide dosing is limited in MGMT unmethylated GBM xenograft models.
    Neuro-oncology, 2013, Volume: 15, Issue:6

    Topics: Animals; Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cell Proliferation; Dacarbaz

2013
Efficacy of protracted temozolomide dosing is limited in MGMT unmethylated GBM xenograft models.
    Neuro-oncology, 2013, Volume: 15, Issue:6

    Topics: Animals; Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cell Proliferation; Dacarbaz

2013
Efficacy of protracted temozolomide dosing is limited in MGMT unmethylated GBM xenograft models.
    Neuro-oncology, 2013, Volume: 15, Issue:6

    Topics: Animals; Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cell Proliferation; Dacarbaz

2013
Leptomeningeal and intramedullary metastases of glioblastoma multiforme in a patient reoperated during adjuvant radiochemotherapy.
    World journal of surgical oncology, 2013, Mar-05, Volume: 11

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy, Adjuvant; Combined Modality T

2013
Leptomeningeal and intramedullary metastases of glioblastoma multiforme in a patient reoperated during adjuvant radiochemotherapy.
    World journal of surgical oncology, 2013, Mar-05, Volume: 11

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy, Adjuvant; Combined Modality T

2013
Leptomeningeal and intramedullary metastases of glioblastoma multiforme in a patient reoperated during adjuvant radiochemotherapy.
    World journal of surgical oncology, 2013, Mar-05, Volume: 11

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy, Adjuvant; Combined Modality T

2013
Combined temozolomide and sunitinib treatment leads to better tumour control but increased vascular resistance in O6-methylguanine methyltransferase-methylated gliomas.
    European journal of cancer (Oxford, England : 1990), 2013, Volume: 49, Issue:9

    Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; C

2013
Combined temozolomide and sunitinib treatment leads to better tumour control but increased vascular resistance in O6-methylguanine methyltransferase-methylated gliomas.
    European journal of cancer (Oxford, England : 1990), 2013, Volume: 49, Issue:9

    Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; C

2013
Combined temozolomide and sunitinib treatment leads to better tumour control but increased vascular resistance in O6-methylguanine methyltransferase-methylated gliomas.
    European journal of cancer (Oxford, England : 1990), 2013, Volume: 49, Issue:9

    Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; C

2013
Molecular analysis of a recurrent glioblastoma treated with bevacizumab.
    Brain tumor pathology, 2014, Volume: 31, Issue:1

    Topics: Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Bevaci

2014
Molecular analysis of a recurrent glioblastoma treated with bevacizumab.
    Brain tumor pathology, 2014, Volume: 31, Issue:1

    Topics: Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Bevaci

2014
Molecular analysis of a recurrent glioblastoma treated with bevacizumab.
    Brain tumor pathology, 2014, Volume: 31, Issue:1

    Topics: Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Bevaci

2014
[Regulation of MGMT and application for the therapy to attenuate the chemoresistance].
    Nihon rinsho. Japanese journal of clinical medicine, 2012, Volume: 70 Suppl 8

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; DNA Modification Methylases; DNA Re

2012
[Regulation of MGMT and application for the therapy to attenuate the chemoresistance].
    Nihon rinsho. Japanese journal of clinical medicine, 2012, Volume: 70 Suppl 8

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; DNA Modification Methylases; DNA Re

2012
[Regulation of MGMT and application for the therapy to attenuate the chemoresistance].
    Nihon rinsho. Japanese journal of clinical medicine, 2012, Volume: 70 Suppl 8

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; DNA Modification Methylases; DNA Re

2012
Predictive value of the SLC22A18 protein expression in glioblastoma patients receiving temozolomide therapy.
    Journal of translational medicine, 2013, Mar-20, Volume: 11

    Topics: Antineoplastic Agents; Blotting, Western; Brain Neoplasms; Dacarbazine; DNA Methylation; Female; Gli

2013
Predictive value of the SLC22A18 protein expression in glioblastoma patients receiving temozolomide therapy.
    Journal of translational medicine, 2013, Mar-20, Volume: 11

    Topics: Antineoplastic Agents; Blotting, Western; Brain Neoplasms; Dacarbazine; DNA Methylation; Female; Gli

2013
Predictive value of the SLC22A18 protein expression in glioblastoma patients receiving temozolomide therapy.
    Journal of translational medicine, 2013, Mar-20, Volume: 11

    Topics: Antineoplastic Agents; Blotting, Western; Brain Neoplasms; Dacarbazine; DNA Methylation; Female; Gli

2013
Effect of lomeguatrib-temozolomide combination on MGMT promoter methylation and expression in primary glioblastoma tumor cells.
    Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine, 2013, Volume: 34, Issue:3

    Topics: Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Blotti

2013
Effect of lomeguatrib-temozolomide combination on MGMT promoter methylation and expression in primary glioblastoma tumor cells.
    Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine, 2013, Volume: 34, Issue:3

    Topics: Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Blotti

2013
Effect of lomeguatrib-temozolomide combination on MGMT promoter methylation and expression in primary glioblastoma tumor cells.
    Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine, 2013, Volume: 34, Issue:3

    Topics: Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Blotti

2013
Valproic acid use during radiation therapy for glioblastoma associated with improved survival.
    International journal of radiation oncology, biology, physics, 2013, Jul-01, Volume: 86, Issue:3

    Topics: Adolescent; Adult; Aged; Anticonvulsants; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combin

2013
Valproic acid use during radiation therapy for glioblastoma associated with improved survival.
    International journal of radiation oncology, biology, physics, 2013, Jul-01, Volume: 86, Issue:3

    Topics: Adolescent; Adult; Aged; Anticonvulsants; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combin

2013
Valproic acid use during radiation therapy for glioblastoma associated with improved survival.
    International journal of radiation oncology, biology, physics, 2013, Jul-01, Volume: 86, Issue:3

    Topics: Adolescent; Adult; Aged; Anticonvulsants; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combin

2013
Outcomes for patients with anaplastic astrocytoma treated with chemoradiation, radiation therapy alone or radiation therapy followed by chemotherapy: a retrospective review within the era of temozolomide.
    Journal of neuro-oncology, 2013, Volume: 113, Issue:2

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Astrocytoma; Brain Ne

2013
Outcomes for patients with anaplastic astrocytoma treated with chemoradiation, radiation therapy alone or radiation therapy followed by chemotherapy: a retrospective review within the era of temozolomide.
    Journal of neuro-oncology, 2013, Volume: 113, Issue:2

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Astrocytoma; Brain Ne

2013
Outcomes for patients with anaplastic astrocytoma treated with chemoradiation, radiation therapy alone or radiation therapy followed by chemotherapy: a retrospective review within the era of temozolomide.
    Journal of neuro-oncology, 2013, Volume: 113, Issue:2

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Astrocytoma; Brain Ne

2013
Focused ultrasound-induced blood-brain barrier opening to enhance temozolomide delivery for glioblastoma treatment: a preclinical study.
    PloS one, 2013, Volume: 8, Issue:3

    Topics: Animals; Antineoplastic Agents, Alkylating; Blood-Brain Barrier; Brain; Brain Neoplasms; Cell Line,

2013
Focused ultrasound-induced blood-brain barrier opening to enhance temozolomide delivery for glioblastoma treatment: a preclinical study.
    PloS one, 2013, Volume: 8, Issue:3

    Topics: Animals; Antineoplastic Agents, Alkylating; Blood-Brain Barrier; Brain; Brain Neoplasms; Cell Line,

2013
Focused ultrasound-induced blood-brain barrier opening to enhance temozolomide delivery for glioblastoma treatment: a preclinical study.
    PloS one, 2013, Volume: 8, Issue:3

    Topics: Animals; Antineoplastic Agents, Alkylating; Blood-Brain Barrier; Brain; Brain Neoplasms; Cell Line,

2013
Myeloablative temozolomide enhances CD8⁺ T-cell responses to vaccine and is required for efficacy against brain tumors in mice.
    PloS one, 2013, Volume: 8, Issue:3

    Topics: Animals; Antigens; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cancer Vaccines; CD8-Positive

2013
Myeloablative temozolomide enhances CD8⁺ T-cell responses to vaccine and is required for efficacy against brain tumors in mice.
    PloS one, 2013, Volume: 8, Issue:3

    Topics: Animals; Antigens; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cancer Vaccines; CD8-Positive

2013
Myeloablative temozolomide enhances CD8⁺ T-cell responses to vaccine and is required for efficacy against brain tumors in mice.
    PloS one, 2013, Volume: 8, Issue:3

    Topics: Animals; Antigens; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cancer Vaccines; CD8-Positive

2013
Pediatric glioblastoma with oligodendroglioma component: aggressive clinical phenotype with distinct molecular characteristics.
    Neuropathology : official journal of the Japanese Society of Neuropathology, 2013, Volume: 33, Issue:6

    Topics: Brain Neoplasms; Chemoradiotherapy; Child; Dacarbazine; Fatal Outcome; Glioblastoma; Humans; Male; M

2013
Pediatric glioblastoma with oligodendroglioma component: aggressive clinical phenotype with distinct molecular characteristics.
    Neuropathology : official journal of the Japanese Society of Neuropathology, 2013, Volume: 33, Issue:6

    Topics: Brain Neoplasms; Chemoradiotherapy; Child; Dacarbazine; Fatal Outcome; Glioblastoma; Humans; Male; M

2013
Pediatric glioblastoma with oligodendroglioma component: aggressive clinical phenotype with distinct molecular characteristics.
    Neuropathology : official journal of the Japanese Society of Neuropathology, 2013, Volume: 33, Issue:6

    Topics: Brain Neoplasms; Chemoradiotherapy; Child; Dacarbazine; Fatal Outcome; Glioblastoma; Humans; Male; M

2013
Increased subventricular zone radiation dose correlates with survival in glioblastoma patients after gross total resection.
    International journal of radiation oncology, biology, physics, 2013, Jul-15, Volume: 86, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Analysis of Variance; Antineoplastic Agents, Alkylating; Brain Neopl

2013
Increased subventricular zone radiation dose correlates with survival in glioblastoma patients after gross total resection.
    International journal of radiation oncology, biology, physics, 2013, Jul-15, Volume: 86, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Analysis of Variance; Antineoplastic Agents, Alkylating; Brain Neopl

2013
Increased subventricular zone radiation dose correlates with survival in glioblastoma patients after gross total resection.
    International journal of radiation oncology, biology, physics, 2013, Jul-15, Volume: 86, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Analysis of Variance; Antineoplastic Agents, Alkylating; Brain Neopl

2013
Durable response of intracranial cellular hemangioma to bevacizumab and temozolomide.
    Journal of neurosurgery. Pediatrics, 2013, Volume: 11, Issue:6

    Topics: Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Brai

2013
Durable response of intracranial cellular hemangioma to bevacizumab and temozolomide.
    Journal of neurosurgery. Pediatrics, 2013, Volume: 11, Issue:6

    Topics: Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Brai

2013
Durable response of intracranial cellular hemangioma to bevacizumab and temozolomide.
    Journal of neurosurgery. Pediatrics, 2013, Volume: 11, Issue:6

    Topics: Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Brai

2013
Cerebellar glioblastoma multiforme: a retrospective study of 28 patients at a single institution.
    The International journal of neuroscience, 2013, Volume: 123, Issue:10

    Topics: Adolescent; Adult; Age Factors; Aged; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Brai

2013
Cerebellar glioblastoma multiforme: a retrospective study of 28 patients at a single institution.
    The International journal of neuroscience, 2013, Volume: 123, Issue:10

    Topics: Adolescent; Adult; Age Factors; Aged; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Brai

2013
Cerebellar glioblastoma multiforme: a retrospective study of 28 patients at a single institution.
    The International journal of neuroscience, 2013, Volume: 123, Issue:10

    Topics: Adolescent; Adult; Age Factors; Aged; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Brai

2013
MiR-139 inhibits Mcl-1 expression and potentiates TMZ-induced apoptosis in glioma.
    CNS neuroscience & therapeutics, 2013, Volume: 19, Issue:7

    Topics: 3' Untranslated Regions; Animals; Antineoplastic Agents, Alkylating; Apoptosis; Blotting, Western; B

2013
MiR-139 inhibits Mcl-1 expression and potentiates TMZ-induced apoptosis in glioma.
    CNS neuroscience & therapeutics, 2013, Volume: 19, Issue:7

    Topics: 3' Untranslated Regions; Animals; Antineoplastic Agents, Alkylating; Apoptosis; Blotting, Western; B

2013
MiR-139 inhibits Mcl-1 expression and potentiates TMZ-induced apoptosis in glioma.
    CNS neuroscience & therapeutics, 2013, Volume: 19, Issue:7

    Topics: 3' Untranslated Regions; Animals; Antineoplastic Agents, Alkylating; Apoptosis; Blotting, Western; B

2013
Organotypic slice cultures of human glioblastoma reveal different susceptibilities to treatments.
    Neuro-oncology, 2013, Volume: 15, Issue:6

    Topics: Adult; Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Carbon; Cell Proliferation; Da

2013
Organotypic slice cultures of human glioblastoma reveal different susceptibilities to treatments.
    Neuro-oncology, 2013, Volume: 15, Issue:6

    Topics: Adult; Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Carbon; Cell Proliferation; Da

2013
Organotypic slice cultures of human glioblastoma reveal different susceptibilities to treatments.
    Neuro-oncology, 2013, Volume: 15, Issue:6

    Topics: Adult; Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Carbon; Cell Proliferation; Da

2013
Apoptosis induction in human glioblastoma multiforme T98G cells upon temozolomide and quercetin treatment.
    Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine, 2013, Volume: 34, Issue:4

    Topics: Antineoplastic Agents, Alkylating; Antioxidants; Apoptosis; Brain Neoplasms; Caspase 12; Caspase 3;

2013
Apoptosis induction in human glioblastoma multiforme T98G cells upon temozolomide and quercetin treatment.
    Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine, 2013, Volume: 34, Issue:4

    Topics: Antineoplastic Agents, Alkylating; Antioxidants; Apoptosis; Brain Neoplasms; Caspase 12; Caspase 3;

2013
Apoptosis induction in human glioblastoma multiforme T98G cells upon temozolomide and quercetin treatment.
    Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine, 2013, Volume: 34, Issue:4

    Topics: Antineoplastic Agents, Alkylating; Antioxidants; Apoptosis; Brain Neoplasms; Caspase 12; Caspase 3;

2013
Development of a preclinical therapeutic model of human brain metastasis with chemoradiotherapy.
    International journal of molecular sciences, 2013, Apr-16, Volume: 14, Issue:4

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Chemoradiotherapy; Da

2013
Development of a preclinical therapeutic model of human brain metastasis with chemoradiotherapy.
    International journal of molecular sciences, 2013, Apr-16, Volume: 14, Issue:4

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Chemoradiotherapy; Da

2013
Development of a preclinical therapeutic model of human brain metastasis with chemoradiotherapy.
    International journal of molecular sciences, 2013, Apr-16, Volume: 14, Issue:4

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Chemoradiotherapy; Da

2013
Relapse in medulloblastoma: what can be done after abandoning high-dose chemotherapy? A mono-institutional experience.
    Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 2013, Volume: 29, Issue:7

    Topics: Administration, Intravenous; Administration, Oral; Adolescent; Adult; Antineoplastic Combined Chemot

2013
Relapse in medulloblastoma: what can be done after abandoning high-dose chemotherapy? A mono-institutional experience.
    Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 2013, Volume: 29, Issue:7

    Topics: Administration, Intravenous; Administration, Oral; Adolescent; Adult; Antineoplastic Combined Chemot

2013
Relapse in medulloblastoma: what can be done after abandoning high-dose chemotherapy? A mono-institutional experience.
    Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 2013, Volume: 29, Issue:7

    Topics: Administration, Intravenous; Administration, Oral; Adolescent; Adult; Antineoplastic Combined Chemot

2013
Caveolin-1 is a negative regulator of tumor growth in glioblastoma and modulates chemosensitivity to temozolomide.
    Cell cycle (Georgetown, Tex.), 2013, May-15, Volume: 12, Issue:10

    Topics: Animals; Apoptosis; Biomarkers, Tumor; Brain Neoplasms; Caveolin 1; Cell Line, Tumor; Dacarbazine; D

2013
Caveolin-1 is a negative regulator of tumor growth in glioblastoma and modulates chemosensitivity to temozolomide.
    Cell cycle (Georgetown, Tex.), 2013, May-15, Volume: 12, Issue:10

    Topics: Animals; Apoptosis; Biomarkers, Tumor; Brain Neoplasms; Caveolin 1; Cell Line, Tumor; Dacarbazine; D

2013
Caveolin-1 is a negative regulator of tumor growth in glioblastoma and modulates chemosensitivity to temozolomide.
    Cell cycle (Georgetown, Tex.), 2013, May-15, Volume: 12, Issue:10

    Topics: Animals; Apoptosis; Biomarkers, Tumor; Brain Neoplasms; Caveolin 1; Cell Line, Tumor; Dacarbazine; D

2013
Concurrent bevacizumab and temozolomide alter the patterns of failure in radiation treatment of glioblastoma multiforme.
    Radiation oncology (London, England), 2013, Apr-25, Volume: 8

    Topics: Adult; Aged; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Beva

2013
Concurrent bevacizumab and temozolomide alter the patterns of failure in radiation treatment of glioblastoma multiforme.
    Radiation oncology (London, England), 2013, Apr-25, Volume: 8

    Topics: Adult; Aged; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Beva

2013
Concurrent bevacizumab and temozolomide alter the patterns of failure in radiation treatment of glioblastoma multiforme.
    Radiation oncology (London, England), 2013, Apr-25, Volume: 8

    Topics: Adult; Aged; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Beva

2013
The mTOR inhibitor RAD001 potentiates autophagic cell death induced by temozolomide in a glioblastoma cell line.
    Anticancer research, 2013, Volume: 33, Issue:5

    Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Autophagy; Blotting, Western; Brain Neopl

2013
The mTOR inhibitor RAD001 potentiates autophagic cell death induced by temozolomide in a glioblastoma cell line.
    Anticancer research, 2013, Volume: 33, Issue:5

    Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Autophagy; Blotting, Western; Brain Neopl

2013
The mTOR inhibitor RAD001 potentiates autophagic cell death induced by temozolomide in a glioblastoma cell line.
    Anticancer research, 2013, Volume: 33, Issue:5

    Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Autophagy; Blotting, Western; Brain Neopl

2013
Glioma cell death induced by irradiation or alkylating agent chemotherapy is independent of the intrinsic ceramide pathway.
    PloS one, 2013, Volume: 8, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Death; Cell Line, Tumor; Cell Proliferation

2013
Glioma cell death induced by irradiation or alkylating agent chemotherapy is independent of the intrinsic ceramide pathway.
    PloS one, 2013, Volume: 8, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Death; Cell Line, Tumor; Cell Proliferation

2013
Glioma cell death induced by irradiation or alkylating agent chemotherapy is independent of the intrinsic ceramide pathway.
    PloS one, 2013, Volume: 8, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Death; Cell Line, Tumor; Cell Proliferation

2013
Immediate post-operative brachytherapy prior to irradiation and temozolomide for newly diagnosed glioblastoma.
    Journal of neuro-oncology, 2013, Volume: 113, Issue:3

    Topics: Aged; Antineoplastic Agents, Alkylating; Brachytherapy; Brain Neoplasms; Case-Control Studies; Chemo

2013
Immediate post-operative brachytherapy prior to irradiation and temozolomide for newly diagnosed glioblastoma.
    Journal of neuro-oncology, 2013, Volume: 113, Issue:3

    Topics: Aged; Antineoplastic Agents, Alkylating; Brachytherapy; Brain Neoplasms; Case-Control Studies; Chemo

2013
Immediate post-operative brachytherapy prior to irradiation and temozolomide for newly diagnosed glioblastoma.
    Journal of neuro-oncology, 2013, Volume: 113, Issue:3

    Topics: Aged; Antineoplastic Agents, Alkylating; Brachytherapy; Brain Neoplasms; Case-Control Studies; Chemo

2013
Defining pseudoprogression in glioblastoma multiforme.
    European journal of neurology, 2013, Volume: 20, Issue:10

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Brain; Brain Neoplasms; Chemoradi

2013
Defining pseudoprogression in glioblastoma multiforme.
    European journal of neurology, 2013, Volume: 20, Issue:10

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Brain; Brain Neoplasms; Chemoradi

2013
Defining pseudoprogression in glioblastoma multiforme.
    European journal of neurology, 2013, Volume: 20, Issue:10

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Brain; Brain Neoplasms; Chemoradi

2013
Effect of valproic acid on seizure control and on survival in patients with glioblastoma multiforme.
    Neuro-oncology, 2013, Volume: 15, Issue:7

    Topics: Adult; Aged; Aged, 80 and over; Anticonvulsants; Antineoplastic Agents, Alkylating; Brain Neoplasms;

2013
Effect of valproic acid on seizure control and on survival in patients with glioblastoma multiforme.
    Neuro-oncology, 2013, Volume: 15, Issue:7

    Topics: Adult; Aged; Aged, 80 and over; Anticonvulsants; Antineoplastic Agents, Alkylating; Brain Neoplasms;

2013
Effect of valproic acid on seizure control and on survival in patients with glioblastoma multiforme.
    Neuro-oncology, 2013, Volume: 15, Issue:7

    Topics: Adult; Aged; Aged, 80 and over; Anticonvulsants; Antineoplastic Agents, Alkylating; Brain Neoplasms;

2013
Activation of executioner caspases is a predictor of progression-free survival in glioblastoma patients: a systems medicine approach.
    Cell death & disease, 2013, May-16, Volume: 4

    Topics: Adult; Aged; Algorithms; Antineoplastic Agents, Alkylating; Apoptosis Regulatory Proteins; Apoptotic

2013
Activation of executioner caspases is a predictor of progression-free survival in glioblastoma patients: a systems medicine approach.
    Cell death & disease, 2013, May-16, Volume: 4

    Topics: Adult; Aged; Algorithms; Antineoplastic Agents, Alkylating; Apoptosis Regulatory Proteins; Apoptotic

2013
Activation of executioner caspases is a predictor of progression-free survival in glioblastoma patients: a systems medicine approach.
    Cell death & disease, 2013, May-16, Volume: 4

    Topics: Adult; Aged; Algorithms; Antineoplastic Agents, Alkylating; Apoptosis Regulatory Proteins; Apoptotic

2013
Plasmablastic lymphoma after standard-dose temozolomide for newly diagnosed glioblastoma.
    Neurology, 2013, Jul-02, Volume: 81, Issue:1

    Topics: Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Glioblastoma; Humans; Lymphom

2013
Plasmablastic lymphoma after standard-dose temozolomide for newly diagnosed glioblastoma.
    Neurology, 2013, Jul-02, Volume: 81, Issue:1

    Topics: Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Glioblastoma; Humans; Lymphom

2013
Plasmablastic lymphoma after standard-dose temozolomide for newly diagnosed glioblastoma.
    Neurology, 2013, Jul-02, Volume: 81, Issue:1

    Topics: Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Glioblastoma; Humans; Lymphom

2013
Connexin43 confers Temozolomide resistance in human glioma cells by modulating the mitochondrial apoptosis pathway.
    Neuropharmacology, 2013, Volume: 75

    Topics: Analysis of Variance; Annexin A5; Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cel

2013
Connexin43 confers Temozolomide resistance in human glioma cells by modulating the mitochondrial apoptosis pathway.
    Neuropharmacology, 2013, Volume: 75

    Topics: Analysis of Variance; Annexin A5; Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cel

2013
Connexin43 confers Temozolomide resistance in human glioma cells by modulating the mitochondrial apoptosis pathway.
    Neuropharmacology, 2013, Volume: 75

    Topics: Analysis of Variance; Annexin A5; Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cel

2013
Trans-1-amino-3-18F-fluorocyclobutanecarboxylic acid (anti-18F-FACBC) is a feasible alternative to 11C-methyl-L-methionine and magnetic resonance imaging for monitoring treatment response in gliomas.
    Nuclear medicine and biology, 2013, Volume: 40, Issue:6

    Topics: Animals; Blood-Brain Barrier; Brain Neoplasms; Carboxylic Acids; Cell Line, Tumor; Cell Proliferatio

2013
Trans-1-amino-3-18F-fluorocyclobutanecarboxylic acid (anti-18F-FACBC) is a feasible alternative to 11C-methyl-L-methionine and magnetic resonance imaging for monitoring treatment response in gliomas.
    Nuclear medicine and biology, 2013, Volume: 40, Issue:6

    Topics: Animals; Blood-Brain Barrier; Brain Neoplasms; Carboxylic Acids; Cell Line, Tumor; Cell Proliferatio

2013
Trans-1-amino-3-18F-fluorocyclobutanecarboxylic acid (anti-18F-FACBC) is a feasible alternative to 11C-methyl-L-methionine and magnetic resonance imaging for monitoring treatment response in gliomas.
    Nuclear medicine and biology, 2013, Volume: 40, Issue:6

    Topics: Animals; Blood-Brain Barrier; Brain Neoplasms; Carboxylic Acids; Cell Line, Tumor; Cell Proliferatio

2013
Glioma initiating cells form a differentiation niche via the induction of extracellular matrices and integrin αV.
    PloS one, 2013, Volume: 8, Issue:5

    Topics: Animals; Brain Neoplasms; Carcinogenesis; Cell Adhesion; Cell Differentiation; Cell Movement; Cell S

2013
Glioma initiating cells form a differentiation niche via the induction of extracellular matrices and integrin αV.
    PloS one, 2013, Volume: 8, Issue:5

    Topics: Animals; Brain Neoplasms; Carcinogenesis; Cell Adhesion; Cell Differentiation; Cell Movement; Cell S

2013
Glioma initiating cells form a differentiation niche via the induction of extracellular matrices and integrin αV.
    PloS one, 2013, Volume: 8, Issue:5

    Topics: Animals; Brain Neoplasms; Carcinogenesis; Cell Adhesion; Cell Differentiation; Cell Movement; Cell S

2013
Restoration of sensitivity in chemo-resistant glioma cells by cold atmospheric plasma.
    PloS one, 2013, Volume: 8, Issue:5

    Topics: Adult; Atmosphere; Brain Neoplasms; Cell Death; Cell Division; Cell Line, Tumor; Cell Proliferation;

2013
Restoration of sensitivity in chemo-resistant glioma cells by cold atmospheric plasma.
    PloS one, 2013, Volume: 8, Issue:5

    Topics: Adult; Atmosphere; Brain Neoplasms; Cell Death; Cell Division; Cell Line, Tumor; Cell Proliferation;

2013
Restoration of sensitivity in chemo-resistant glioma cells by cold atmospheric plasma.
    PloS one, 2013, Volume: 8, Issue:5

    Topics: Adult; Atmosphere; Brain Neoplasms; Cell Death; Cell Division; Cell Line, Tumor; Cell Proliferation;

2013
Synergistic interactions between camptothecin and EGFR or RAC1 inhibitors and between imatinib and Notch signaling or RAC1 inhibitors in glioblastoma cell lines.
    Cancer chemotherapy and pharmacology, 2013, Volume: 72, Issue:2

    Topics: Antineoplastic Agents, Alkylating; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemot

2013
Synergistic interactions between camptothecin and EGFR or RAC1 inhibitors and between imatinib and Notch signaling or RAC1 inhibitors in glioblastoma cell lines.
    Cancer chemotherapy and pharmacology, 2013, Volume: 72, Issue:2

    Topics: Antineoplastic Agents, Alkylating; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemot

2013
Synergistic interactions between camptothecin and EGFR or RAC1 inhibitors and between imatinib and Notch signaling or RAC1 inhibitors in glioblastoma cell lines.
    Cancer chemotherapy and pharmacology, 2013, Volume: 72, Issue:2

    Topics: Antineoplastic Agents, Alkylating; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemot

2013
Factors predicting temozolomide induced clinically significant acute hematologic toxicity in patients with high-grade gliomas: a clinical audit.
    Clinical neurology and neurosurgery, 2013, Volume: 115, Issue:9

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cohort Studies; Community-Acquired

2013
Factors predicting temozolomide induced clinically significant acute hematologic toxicity in patients with high-grade gliomas: a clinical audit.
    Clinical neurology and neurosurgery, 2013, Volume: 115, Issue:9

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cohort Studies; Community-Acquired

2013
Factors predicting temozolomide induced clinically significant acute hematologic toxicity in patients with high-grade gliomas: a clinical audit.
    Clinical neurology and neurosurgery, 2013, Volume: 115, Issue:9

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cohort Studies; Community-Acquired

2013
Differentiation of true progression from pseudoprogression in glioblastoma treated with radiation therapy and concomitant temozolomide: comparison study of standard and high-b-value diffusion-weighted imaging.
    Radiology, 2013, Volume: 269, Issue:3

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Dacarbazine; Dif

2013
Differentiation of true progression from pseudoprogression in glioblastoma treated with radiation therapy and concomitant temozolomide: comparison study of standard and high-b-value diffusion-weighted imaging.
    Radiology, 2013, Volume: 269, Issue:3

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Dacarbazine; Dif

2013
Differentiation of true progression from pseudoprogression in glioblastoma treated with radiation therapy and concomitant temozolomide: comparison study of standard and high-b-value diffusion-weighted imaging.
    Radiology, 2013, Volume: 269, Issue:3

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Dacarbazine; Dif

2013
Melanoma of unknown primary origin presenting as a rapidly enlarging adrenal mass.
    BMJ case reports, 2013, Jun-19, Volume: 2013

    Topics: Adrenal Gland Neoplasms; Aged; Antineoplastic Agents; Brain Neoplasms; Combined Modality Therapy; Da

2013
Melanoma of unknown primary origin presenting as a rapidly enlarging adrenal mass.
    BMJ case reports, 2013, Jun-19, Volume: 2013

    Topics: Adrenal Gland Neoplasms; Aged; Antineoplastic Agents; Brain Neoplasms; Combined Modality Therapy; Da

2013
Melanoma of unknown primary origin presenting as a rapidly enlarging adrenal mass.
    BMJ case reports, 2013, Jun-19, Volume: 2013

    Topics: Adrenal Gland Neoplasms; Aged; Antineoplastic Agents; Brain Neoplasms; Combined Modality Therapy; Da

2013
Should we continue temozolomide beyond six cycles in the adjuvant treatment of glioblastoma without an evidence of clinical benefit? A cost analysis based on prescribing patterns in Spain.
    Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico, 2014, Volume: 16, Issue:3

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant; Cost-Benefit Analysis; D

2014
Should we continue temozolomide beyond six cycles in the adjuvant treatment of glioblastoma without an evidence of clinical benefit? A cost analysis based on prescribing patterns in Spain.
    Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico, 2014, Volume: 16, Issue:3

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant; Cost-Benefit Analysis; D

2014
Should we continue temozolomide beyond six cycles in the adjuvant treatment of glioblastoma without an evidence of clinical benefit? A cost analysis based on prescribing patterns in Spain.
    Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico, 2014, Volume: 16, Issue:3

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant; Cost-Benefit Analysis; D

2014
Solitary brain metastasis as first manifestation of small-cell parotid gland carcinoma with high sensitivity to temozolomide therapy on basis of tumor O6-methylguanine-DNA-methyltransferase expression.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2013, Aug-10, Volume: 31, Issue:23

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Carcinoma, Small Cell; Dacarbazine; Female; Huma

2013
Solitary brain metastasis as first manifestation of small-cell parotid gland carcinoma with high sensitivity to temozolomide therapy on basis of tumor O6-methylguanine-DNA-methyltransferase expression.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2013, Aug-10, Volume: 31, Issue:23

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Carcinoma, Small Cell; Dacarbazine; Female; Huma

2013
Solitary brain metastasis as first manifestation of small-cell parotid gland carcinoma with high sensitivity to temozolomide therapy on basis of tumor O6-methylguanine-DNA-methyltransferase expression.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2013, Aug-10, Volume: 31, Issue:23

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Carcinoma, Small Cell; Dacarbazine; Female; Huma

2013
The ZEB1 pathway links glioblastoma initiation, invasion and chemoresistance.
    EMBO molecular medicine, 2013, Volume: 5, Issue:8

    Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Cell Line, Tumor; Cell Survival; Dacarbazine; DNA M

2013
The ZEB1 pathway links glioblastoma initiation, invasion and chemoresistance.
    EMBO molecular medicine, 2013, Volume: 5, Issue:8

    Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Cell Line, Tumor; Cell Survival; Dacarbazine; DNA M

2013
The ZEB1 pathway links glioblastoma initiation, invasion and chemoresistance.
    EMBO molecular medicine, 2013, Volume: 5, Issue:8

    Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Cell Line, Tumor; Cell Survival; Dacarbazine; DNA M

2013
Extracellular sphingosine-1-phosphate: a novel actor in human glioblastoma stem cell survival.
    PloS one, 2013, Volume: 8, Issue:6

    Topics: Brain Neoplasms; Cell Line, Tumor; Cell Separation; Cell Survival; Dacarbazine; Drug Resistance, Neo

2013
Extracellular sphingosine-1-phosphate: a novel actor in human glioblastoma stem cell survival.
    PloS one, 2013, Volume: 8, Issue:6

    Topics: Brain Neoplasms; Cell Line, Tumor; Cell Separation; Cell Survival; Dacarbazine; Drug Resistance, Neo

2013
Extracellular sphingosine-1-phosphate: a novel actor in human glioblastoma stem cell survival.
    PloS one, 2013, Volume: 8, Issue:6

    Topics: Brain Neoplasms; Cell Line, Tumor; Cell Separation; Cell Survival; Dacarbazine; Drug Resistance, Neo

2013
Pulsed versus conventional radiation therapy in combination with temozolomide in a murine orthotopic model of glioblastoma multiforme.
    International journal of radiation oncology, biology, physics, 2013, Aug-01, Volume: 86, Issue:5

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Cranial Irra

2013
Pulsed versus conventional radiation therapy in combination with temozolomide in a murine orthotopic model of glioblastoma multiforme.
    International journal of radiation oncology, biology, physics, 2013, Aug-01, Volume: 86, Issue:5

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Cranial Irra

2013
Pulsed versus conventional radiation therapy in combination with temozolomide in a murine orthotopic model of glioblastoma multiforme.
    International journal of radiation oncology, biology, physics, 2013, Aug-01, Volume: 86, Issue:5

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Cranial Irra

2013
LRIG1 dictates the chemo-sensitivity of temozolomide (TMZ) in U251 glioblastoma cells via down-regulation of EGFR/topoisomerase-2/Bcl-2.
    Biochemical and biophysical research communications, 2013, Aug-09, Volume: 437, Issue:4

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Cell Survival; Dacarbazine; DN

2013
LRIG1 dictates the chemo-sensitivity of temozolomide (TMZ) in U251 glioblastoma cells via down-regulation of EGFR/topoisomerase-2/Bcl-2.
    Biochemical and biophysical research communications, 2013, Aug-09, Volume: 437, Issue:4

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Cell Survival; Dacarbazine; DN

2013
LRIG1 dictates the chemo-sensitivity of temozolomide (TMZ) in U251 glioblastoma cells via down-regulation of EGFR/topoisomerase-2/Bcl-2.
    Biochemical and biophysical research communications, 2013, Aug-09, Volume: 437, Issue:4

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Cell Survival; Dacarbazine; DN

2013
Early assessment of the efficacy of temozolomide chemotherapy in experimental glioblastoma using [18F]FLT-PET imaging.
    PloS one, 2013, Volume: 8, Issue:7

    Topics: Animals; Antineoplastic Agents, Alkylating; Biomarkers, Pharmacological; Brain Neoplasms; Dacarbazin

2013
Early assessment of the efficacy of temozolomide chemotherapy in experimental glioblastoma using [18F]FLT-PET imaging.
    PloS one, 2013, Volume: 8, Issue:7

    Topics: Animals; Antineoplastic Agents, Alkylating; Biomarkers, Pharmacological; Brain Neoplasms; Dacarbazin

2013
Early assessment of the efficacy of temozolomide chemotherapy in experimental glioblastoma using [18F]FLT-PET imaging.
    PloS one, 2013, Volume: 8, Issue:7

    Topics: Animals; Antineoplastic Agents, Alkylating; Biomarkers, Pharmacological; Brain Neoplasms; Dacarbazin

2013
Observational, retrospective study of the effectiveness of 5-aminolevulinic acid in malignant glioma surgery in Spain (The VISIONA study).
    Neurologia (Barcelona, Spain), 2014, Volume: 29, Issue:3

    Topics: Aminolevulinic Acid; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Disease-Free S

2014
Observational, retrospective study of the effectiveness of 5-aminolevulinic acid in malignant glioma surgery in Spain (The VISIONA study).
    Neurologia (Barcelona, Spain), 2014, Volume: 29, Issue:3

    Topics: Aminolevulinic Acid; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Disease-Free S

2014
Observational, retrospective study of the effectiveness of 5-aminolevulinic acid in malignant glioma surgery in Spain (The VISIONA study).
    Neurologia (Barcelona, Spain), 2014, Volume: 29, Issue:3

    Topics: Aminolevulinic Acid; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Disease-Free S

2014
Antitumor activity of (2E,5Z)-5-(2-hydroxybenzylidene)-2-((4-phenoxyphenyl)imino) thiazolidin-4-one, a novel microtubule-depolymerizing agent, in U87MG human glioblastoma cells and corresponding mouse xenograft model.
    Journal of pharmacological sciences, 2013, Volume: 122, Issue:3

    Topics: Animals; Antineoplastic Agents; Apoptosis; Brain Neoplasms; Cell Division; Cell Proliferation; Dacar

2013
Antitumor activity of (2E,5Z)-5-(2-hydroxybenzylidene)-2-((4-phenoxyphenyl)imino) thiazolidin-4-one, a novel microtubule-depolymerizing agent, in U87MG human glioblastoma cells and corresponding mouse xenograft model.
    Journal of pharmacological sciences, 2013, Volume: 122, Issue:3

    Topics: Animals; Antineoplastic Agents; Apoptosis; Brain Neoplasms; Cell Division; Cell Proliferation; Dacar

2013
Antitumor activity of (2E,5Z)-5-(2-hydroxybenzylidene)-2-((4-phenoxyphenyl)imino) thiazolidin-4-one, a novel microtubule-depolymerizing agent, in U87MG human glioblastoma cells and corresponding mouse xenograft model.
    Journal of pharmacological sciences, 2013, Volume: 122, Issue:3

    Topics: Animals; Antineoplastic Agents; Apoptosis; Brain Neoplasms; Cell Division; Cell Proliferation; Dacar

2013
Polo-like kinase 1 inhibition causes decreased proliferation by cell cycle arrest, leading to cell death in glioblastoma.
    Cancer gene therapy, 2013, Volume: 20, Issue:9

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Cycle Checkpoints; Cell Cycle Proteins; Cel

2013
Polo-like kinase 1 inhibition causes decreased proliferation by cell cycle arrest, leading to cell death in glioblastoma.
    Cancer gene therapy, 2013, Volume: 20, Issue:9

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Cycle Checkpoints; Cell Cycle Proteins; Cel

2013
Polo-like kinase 1 inhibition causes decreased proliferation by cell cycle arrest, leading to cell death in glioblastoma.
    Cancer gene therapy, 2013, Volume: 20, Issue:9

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Cycle Checkpoints; Cell Cycle Proteins; Cel

2013
Enhanced accumulation of curcumin and temozolomide loaded magnetic nanoparticles executes profound cytotoxic effect in glioblastoma spheroid model.
    European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 2013, Volume: 85, Issue:3 Pt A

    Topics: Acridine Orange; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Brain Neoplasms; Cell Cu

2013
Enhanced accumulation of curcumin and temozolomide loaded magnetic nanoparticles executes profound cytotoxic effect in glioblastoma spheroid model.
    European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 2013, Volume: 85, Issue:3 Pt A

    Topics: Acridine Orange; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Brain Neoplasms; Cell Cu

2013
Enhanced accumulation of curcumin and temozolomide loaded magnetic nanoparticles executes profound cytotoxic effect in glioblastoma spheroid model.
    European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 2013, Volume: 85, Issue:3 Pt A

    Topics: Acridine Orange; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Brain Neoplasms; Cell Cu

2013
Convection-enhanced delivery and in vivo imaging of polymeric nanoparticles for the treatment of malignant glioma.
    Nanomedicine : nanotechnology, biology, and medicine, 2014, Volume: 10, Issue:1

    Topics: Animals; Brain Neoplasms; Cell Line, Tumor; Convection; Dacarbazine; Drug Delivery Systems; Ferric C

2014
Convection-enhanced delivery and in vivo imaging of polymeric nanoparticles for the treatment of malignant glioma.
    Nanomedicine : nanotechnology, biology, and medicine, 2014, Volume: 10, Issue:1

    Topics: Animals; Brain Neoplasms; Cell Line, Tumor; Convection; Dacarbazine; Drug Delivery Systems; Ferric C

2014
Convection-enhanced delivery and in vivo imaging of polymeric nanoparticles for the treatment of malignant glioma.
    Nanomedicine : nanotechnology, biology, and medicine, 2014, Volume: 10, Issue:1

    Topics: Animals; Brain Neoplasms; Cell Line, Tumor; Convection; Dacarbazine; Drug Delivery Systems; Ferric C

2014
Temozolomide downregulates P-glycoprotein expression in glioblastoma stem cells by interfering with the Wnt3a/glycogen synthase-3 kinase/β-catenin pathway.
    Neuro-oncology, 2013, Volume: 15, Issue:11

    Topics: Animals; Antineoplastic Agents, Alkylating; ATP Binding Cassette Transporter, Subfamily B; ATP Bindi

2013
Temozolomide downregulates P-glycoprotein expression in glioblastoma stem cells by interfering with the Wnt3a/glycogen synthase-3 kinase/β-catenin pathway.
    Neuro-oncology, 2013, Volume: 15, Issue:11

    Topics: Animals; Antineoplastic Agents, Alkylating; ATP Binding Cassette Transporter, Subfamily B; ATP Bindi

2013
Temozolomide downregulates P-glycoprotein expression in glioblastoma stem cells by interfering with the Wnt3a/glycogen synthase-3 kinase/β-catenin pathway.
    Neuro-oncology, 2013, Volume: 15, Issue:11

    Topics: Animals; Antineoplastic Agents, Alkylating; ATP Binding Cassette Transporter, Subfamily B; ATP Bindi

2013
Prolonged administration of adjuvant temozolomide improves survival in adult patients with glioblastoma.
    Anticancer research, 2013, Volume: 33, Issue:8

    Topics: Adolescent; Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms

2013
Prolonged administration of adjuvant temozolomide improves survival in adult patients with glioblastoma.
    Anticancer research, 2013, Volume: 33, Issue:8

    Topics: Adolescent; Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms

2013
Prolonged administration of adjuvant temozolomide improves survival in adult patients with glioblastoma.
    Anticancer research, 2013, Volume: 33, Issue:8

    Topics: Adolescent; Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms

2013
Cytoplasmic TRADD confers a worse prognosis in glioblastoma.
    Neoplasia (New York, N.Y.), 2013, Volume: 15, Issue:8

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Blotting, Western; Brain Neoplasms; Cell Line, Tumor

2013
Cytoplasmic TRADD confers a worse prognosis in glioblastoma.
    Neoplasia (New York, N.Y.), 2013, Volume: 15, Issue:8

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Blotting, Western; Brain Neoplasms; Cell Line, Tumor

2013
Cytoplasmic TRADD confers a worse prognosis in glioblastoma.
    Neoplasia (New York, N.Y.), 2013, Volume: 15, Issue:8

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Blotting, Western; Brain Neoplasms; Cell Line, Tumor

2013
Comparison of the clinical efficacy of temozolomide (TMZ) versus nimustine (ACNU)-based chemotherapy in newly diagnosed glioblastoma.
    Neurosurgical review, 2014, Volume: 37, Issue:1

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Brain Neoplasms;

2014
Comparison of the clinical efficacy of temozolomide (TMZ) versus nimustine (ACNU)-based chemotherapy in newly diagnosed glioblastoma.
    Neurosurgical review, 2014, Volume: 37, Issue:1

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Brain Neoplasms;

2014
Comparison of the clinical efficacy of temozolomide (TMZ) versus nimustine (ACNU)-based chemotherapy in newly diagnosed glioblastoma.
    Neurosurgical review, 2014, Volume: 37, Issue:1

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Brain Neoplasms;

2014
The timing of neural stem cell-based virotherapy is critical for optimal therapeutic efficacy when applied with radiation and chemotherapy for the treatment of glioblastoma.
    Stem cells translational medicine, 2013, Volume: 2, Issue:9

    Topics: Adenoviridae; Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Transformed; C

2013
The timing of neural stem cell-based virotherapy is critical for optimal therapeutic efficacy when applied with radiation and chemotherapy for the treatment of glioblastoma.
    Stem cells translational medicine, 2013, Volume: 2, Issue:9

    Topics: Adenoviridae; Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Transformed; C

2013
The timing of neural stem cell-based virotherapy is critical for optimal therapeutic efficacy when applied with radiation and chemotherapy for the treatment of glioblastoma.
    Stem cells translational medicine, 2013, Volume: 2, Issue:9

    Topics: Adenoviridae; Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Transformed; C

2013
Central diabetes insipidus: a previously unreported side effect of temozolomide.
    The Journal of clinical endocrinology and metabolism, 2013, Volume: 98, Issue:10

    Topics: Adult; Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neoplasms; Dacarbazine; Diabetes Insipi

2013
Central diabetes insipidus: a previously unreported side effect of temozolomide.
    The Journal of clinical endocrinology and metabolism, 2013, Volume: 98, Issue:10

    Topics: Adult; Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neoplasms; Dacarbazine; Diabetes Insipi

2013
Central diabetes insipidus: a previously unreported side effect of temozolomide.
    The Journal of clinical endocrinology and metabolism, 2013, Volume: 98, Issue:10

    Topics: Adult; Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neoplasms; Dacarbazine; Diabetes Insipi

2013
Comparison of carbon ion radiotherapy to photon radiation alone or in combination with temozolomide in patients with high-grade gliomas: explorative hypothesis-generating retrospective analysis.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2013, Volume: 108, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Child; Child, Preschool; Daca

2013
Comparison of carbon ion radiotherapy to photon radiation alone or in combination with temozolomide in patients with high-grade gliomas: explorative hypothesis-generating retrospective analysis.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2013, Volume: 108, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Child; Child, Preschool; Daca

2013
Comparison of carbon ion radiotherapy to photon radiation alone or in combination with temozolomide in patients with high-grade gliomas: explorative hypothesis-generating retrospective analysis.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2013, Volume: 108, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Child; Child, Preschool; Daca

2013
Chemoirradiation for glioblastoma multiforme: the national cancer institute experience.
    PloS one, 2013, Volume: 8, Issue:8

    Topics: Adult; Aged; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Antineoplastic Agents, Alky

2013
Chemoirradiation for glioblastoma multiforme: the national cancer institute experience.
    PloS one, 2013, Volume: 8, Issue:8

    Topics: Adult; Aged; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Antineoplastic Agents, Alky

2013
Chemoirradiation for glioblastoma multiforme: the national cancer institute experience.
    PloS one, 2013, Volume: 8, Issue:8

    Topics: Adult; Aged; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Antineoplastic Agents, Alky

2013
The Cdk inhibitor flavopiridol enhances temozolomide-induced cytotoxicity in human glioma cells.
    Journal of neuro-oncology, 2013, Volume: 115, Issue:2

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Cycle; Colony-Forming Units Assay;

2013
The Cdk inhibitor flavopiridol enhances temozolomide-induced cytotoxicity in human glioma cells.
    Journal of neuro-oncology, 2013, Volume: 115, Issue:2

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Cycle; Colony-Forming Units Assay;

2013
The Cdk inhibitor flavopiridol enhances temozolomide-induced cytotoxicity in human glioma cells.
    Journal of neuro-oncology, 2013, Volume: 115, Issue:2

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Cycle; Colony-Forming Units Assay;

2013
An automated system for detecting nonadherence in laboratory testing and monitoring for myelosuppression in patients receiving self-administered oral chemotherapy.
    Journal of oncology practice, 2013, Volume: 9, Issue:5

    Topics: Administration, Oral; Adult; Aged; Antineoplastic Agents, Alkylating; Blood Cell Count; Brain Neopla

2013
An automated system for detecting nonadherence in laboratory testing and monitoring for myelosuppression in patients receiving self-administered oral chemotherapy.
    Journal of oncology practice, 2013, Volume: 9, Issue:5

    Topics: Administration, Oral; Adult; Aged; Antineoplastic Agents, Alkylating; Blood Cell Count; Brain Neopla

2013
An automated system for detecting nonadherence in laboratory testing and monitoring for myelosuppression in patients receiving self-administered oral chemotherapy.
    Journal of oncology practice, 2013, Volume: 9, Issue:5

    Topics: Administration, Oral; Adult; Aged; Antineoplastic Agents, Alkylating; Blood Cell Count; Brain Neopla

2013
Establishment and characterization of primary glioblastoma cell lines from fresh and frozen material: a detailed comparison.
    PloS one, 2013, Volume: 8, Issue:8

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Benzamides; Brain Neoplasms; Carmustine; Cell

2013
Establishment and characterization of primary glioblastoma cell lines from fresh and frozen material: a detailed comparison.
    PloS one, 2013, Volume: 8, Issue:8

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Benzamides; Brain Neoplasms; Carmustine; Cell

2013
Establishment and characterization of primary glioblastoma cell lines from fresh and frozen material: a detailed comparison.
    PloS one, 2013, Volume: 8, Issue:8

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Benzamides; Brain Neoplasms; Carmustine; Cell

2013
Stupp-treated glioblastoma accompanied by EBV-positive primary CNS lymphoma.
    British journal of neurosurgery, 2014, Volume: 28, Issue:2

    Topics: Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Clinical Protocols; Dac

2014
Stupp-treated glioblastoma accompanied by EBV-positive primary CNS lymphoma.
    British journal of neurosurgery, 2014, Volume: 28, Issue:2

    Topics: Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Clinical Protocols; Dac

2014
Stupp-treated glioblastoma accompanied by EBV-positive primary CNS lymphoma.
    British journal of neurosurgery, 2014, Volume: 28, Issue:2

    Topics: Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Clinical Protocols; Dac

2014
Toca 511 gene transfer and 5-fluorocytosine in combination with temozolomide demonstrates synergistic therapeutic efficacy in a temozolomide-sensitive glioblastoma model.
    Cancer gene therapy, 2013, Volume: 20, Issue:10

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Cytosine Deaminase; Dacarb

2013
Toca 511 gene transfer and 5-fluorocytosine in combination with temozolomide demonstrates synergistic therapeutic efficacy in a temozolomide-sensitive glioblastoma model.
    Cancer gene therapy, 2013, Volume: 20, Issue:10

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Cytosine Deaminase; Dacarb

2013
Toca 511 gene transfer and 5-fluorocytosine in combination with temozolomide demonstrates synergistic therapeutic efficacy in a temozolomide-sensitive glioblastoma model.
    Cancer gene therapy, 2013, Volume: 20, Issue:10

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Cytosine Deaminase; Dacarb

2013
Meningeal seeding from glioblastoma multiforme treated with radiotherapy and temozolomide.
    Asian journal of surgery, 2017, Volume: 40, Issue:1

    Topics: Adult; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy, Adjuvant; Dacarbazine;

2017
Meningeal seeding from glioblastoma multiforme treated with radiotherapy and temozolomide.
    Asian journal of surgery, 2017, Volume: 40, Issue:1

    Topics: Adult; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy, Adjuvant; Dacarbazine;

2017
Meningeal seeding from glioblastoma multiforme treated with radiotherapy and temozolomide.
    Asian journal of surgery, 2017, Volume: 40, Issue:1

    Topics: Adult; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy, Adjuvant; Dacarbazine;

2017
Glioblastoma management in the temozolomide era: have we improved outcome?
    Journal of neuro-oncology, 2013, Volume: 115, Issue:2

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Daca

2013
Glioblastoma management in the temozolomide era: have we improved outcome?
    Journal of neuro-oncology, 2013, Volume: 115, Issue:2

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Daca

2013
Glioblastoma management in the temozolomide era: have we improved outcome?
    Journal of neuro-oncology, 2013, Volume: 115, Issue:2

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Daca

2013
Concomitant and adjuvant temozolomide of newly diagnosed glioblastoma in elderly patients.
    Clinical neurology and neurosurgery, 2013, Volume: 115, Issue:10

    Topics: Adult; Age Factors; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Che

2013
Concomitant and adjuvant temozolomide of newly diagnosed glioblastoma in elderly patients.
    Clinical neurology and neurosurgery, 2013, Volume: 115, Issue:10

    Topics: Adult; Age Factors; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Che

2013
Concomitant and adjuvant temozolomide of newly diagnosed glioblastoma in elderly patients.
    Clinical neurology and neurosurgery, 2013, Volume: 115, Issue:10

    Topics: Adult; Age Factors; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Che

2013
Triacetin-based acetate supplementation as a chemotherapeutic adjuvant therapy in glioma.
    International journal of cancer, 2014, Mar-15, Volume: 134, Issue:6

    Topics: Amidohydrolases; Animals; Antifungal Agents; Aspartic Acid; Astrocytes; Brain; Brain Neoplasms; Cell

2014
Triacetin-based acetate supplementation as a chemotherapeutic adjuvant therapy in glioma.
    International journal of cancer, 2014, Mar-15, Volume: 134, Issue:6

    Topics: Amidohydrolases; Animals; Antifungal Agents; Aspartic Acid; Astrocytes; Brain; Brain Neoplasms; Cell

2014
Triacetin-based acetate supplementation as a chemotherapeutic adjuvant therapy in glioma.
    International journal of cancer, 2014, Mar-15, Volume: 134, Issue:6

    Topics: Amidohydrolases; Animals; Antifungal Agents; Aspartic Acid; Astrocytes; Brain; Brain Neoplasms; Cell

2014
Clinical variables serve as prognostic factors in a model for survival from glioblastoma multiforme: an observational study of a cohort of consecutive non-selected patients from a single institution.
    BMC cancer, 2013, Sep-03, Volume: 13

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Biom

2013
Clinical variables serve as prognostic factors in a model for survival from glioblastoma multiforme: an observational study of a cohort of consecutive non-selected patients from a single institution.
    BMC cancer, 2013, Sep-03, Volume: 13

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Biom

2013
Clinical variables serve as prognostic factors in a model for survival from glioblastoma multiforme: an observational study of a cohort of consecutive non-selected patients from a single institution.
    BMC cancer, 2013, Sep-03, Volume: 13

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Biom

2013
Glioblastoma occurring after the surgical resection of a craniopharyngioma.
    British journal of neurosurgery, 2014, Volume: 28, Issue:2

    Topics: Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Clinical Protocols; Cra

2014
Glioblastoma occurring after the surgical resection of a craniopharyngioma.
    British journal of neurosurgery, 2014, Volume: 28, Issue:2

    Topics: Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Clinical Protocols; Cra

2014
Glioblastoma occurring after the surgical resection of a craniopharyngioma.
    British journal of neurosurgery, 2014, Volume: 28, Issue:2

    Topics: Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Clinical Protocols; Cra

2014
YB-1 dependent oncolytic adenovirus efficiently inhibits tumor growth of glioma cancer stem like cells.
    Journal of translational medicine, 2013, Sep-18, Volume: 11

    Topics: Adenoviridae; Animals; Astrocytes; Brain Neoplasms; Cell Hypoxia; Cell Line, Tumor; Cell Proliferati

2013
YB-1 dependent oncolytic adenovirus efficiently inhibits tumor growth of glioma cancer stem like cells.
    Journal of translational medicine, 2013, Sep-18, Volume: 11

    Topics: Adenoviridae; Animals; Astrocytes; Brain Neoplasms; Cell Hypoxia; Cell Line, Tumor; Cell Proliferati

2013
YB-1 dependent oncolytic adenovirus efficiently inhibits tumor growth of glioma cancer stem like cells.
    Journal of translational medicine, 2013, Sep-18, Volume: 11

    Topics: Adenoviridae; Animals; Astrocytes; Brain Neoplasms; Cell Hypoxia; Cell Line, Tumor; Cell Proliferati

2013
miR-125b inhibits Connexin43 and promotes glioma growth.
    Cellular and molecular neurobiology, 2013, Volume: 33, Issue:8

    Topics: 3' Untranslated Regions; Animals; Apoptosis; Base Sequence; Brain Neoplasms; Cell Line, Tumor; Cell

2013
miR-125b inhibits Connexin43 and promotes glioma growth.
    Cellular and molecular neurobiology, 2013, Volume: 33, Issue:8

    Topics: 3' Untranslated Regions; Animals; Apoptosis; Base Sequence; Brain Neoplasms; Cell Line, Tumor; Cell

2013
miR-125b inhibits Connexin43 and promotes glioma growth.
    Cellular and molecular neurobiology, 2013, Volume: 33, Issue:8

    Topics: 3' Untranslated Regions; Animals; Apoptosis; Base Sequence; Brain Neoplasms; Cell Line, Tumor; Cell

2013
Time trends in glioblastoma multiforme survival: the role of temozolomide.
    Neuro-oncology, 2013, Volume: 15, Issue:12

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Brai

2013
Time trends in glioblastoma multiforme survival: the role of temozolomide.
    Neuro-oncology, 2013, Volume: 15, Issue:12

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Brai

2013
Time trends in glioblastoma multiforme survival: the role of temozolomide.
    Neuro-oncology, 2013, Volume: 15, Issue:12

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Brai

2013
Mitochondrial protein ATPase family, AAA domain containing 3A correlates with radioresistance in glioblastoma.
    Neuro-oncology, 2013, Volume: 15, Issue:10

    Topics: Adenosine Triphosphatases; Antineoplastic Agents, Alkylating; ATPases Associated with Diverse Cellul

2013
Mitochondrial protein ATPase family, AAA domain containing 3A correlates with radioresistance in glioblastoma.
    Neuro-oncology, 2013, Volume: 15, Issue:10

    Topics: Adenosine Triphosphatases; Antineoplastic Agents, Alkylating; ATPases Associated with Diverse Cellul

2013
Mitochondrial protein ATPase family, AAA domain containing 3A correlates with radioresistance in glioblastoma.
    Neuro-oncology, 2013, Volume: 15, Issue:10

    Topics: Adenosine Triphosphatases; Antineoplastic Agents, Alkylating; ATPases Associated with Diverse Cellul

2013
Long-term treatment with temozolomide in malignant glioma.
    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2014, Volume: 21, Issue:1

    Topics: Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Combin

2014
Long-term treatment with temozolomide in malignant glioma.
    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2014, Volume: 21, Issue:1

    Topics: Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Combin

2014
Long-term treatment with temozolomide in malignant glioma.
    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2014, Volume: 21, Issue:1

    Topics: Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Combin

2014
The temozolomide derivative 2T-P400 inhibits glioma growth via administration route of intravenous injection.
    Journal of neuro-oncology, 2014, Volume: 116, Issue:1

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; D

2014
The temozolomide derivative 2T-P400 inhibits glioma growth via administration route of intravenous injection.
    Journal of neuro-oncology, 2014, Volume: 116, Issue:1

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; D

2014
The temozolomide derivative 2T-P400 inhibits glioma growth via administration route of intravenous injection.
    Journal of neuro-oncology, 2014, Volume: 116, Issue:1

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; D

2014
Temozolomide and irradiation combined treatment-induced Nrf2 activation increases chemoradiation sensitivity in human glioblastoma cells.
    Journal of neuro-oncology, 2014, Volume: 116, Issue:1

    Topics: Adult; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Dacarbazine; Down-Regul

2014
Temozolomide and irradiation combined treatment-induced Nrf2 activation increases chemoradiation sensitivity in human glioblastoma cells.
    Journal of neuro-oncology, 2014, Volume: 116, Issue:1

    Topics: Adult; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Dacarbazine; Down-Regul

2014
Temozolomide and irradiation combined treatment-induced Nrf2 activation increases chemoradiation sensitivity in human glioblastoma cells.
    Journal of neuro-oncology, 2014, Volume: 116, Issue:1

    Topics: Adult; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Dacarbazine; Down-Regul

2014
A case of adult onset medulloblastoma during maintenance chemotherapy for anaplastic astrocytoma one year after radiotherapy.
    Turkish neurosurgery, 2013, Volume: 23, Issue:4

    Topics: Adult; Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neoplasms; Cerebellar Neoplasms; Chemor

2013
A case of adult onset medulloblastoma during maintenance chemotherapy for anaplastic astrocytoma one year after radiotherapy.
    Turkish neurosurgery, 2013, Volume: 23, Issue:4

    Topics: Adult; Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neoplasms; Cerebellar Neoplasms; Chemor

2013
A case of adult onset medulloblastoma during maintenance chemotherapy for anaplastic astrocytoma one year after radiotherapy.
    Turkish neurosurgery, 2013, Volume: 23, Issue:4

    Topics: Adult; Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neoplasms; Cerebellar Neoplasms; Chemor

2013
A survival analysis of GBM patients in the West of Scotland pre- and post-introduction of the Stupp regime.
    British journal of neurosurgery, 2014, Volume: 28, Issue:3

    Topics: Adolescent; Adult; Age Factors; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradio

2014
A survival analysis of GBM patients in the West of Scotland pre- and post-introduction of the Stupp regime.
    British journal of neurosurgery, 2014, Volume: 28, Issue:3

    Topics: Adolescent; Adult; Age Factors; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradio

2014
A survival analysis of GBM patients in the West of Scotland pre- and post-introduction of the Stupp regime.
    British journal of neurosurgery, 2014, Volume: 28, Issue:3

    Topics: Adolescent; Adult; Age Factors; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradio

2014
Biliverdin reductase plays a crucial role in hypoxia-induced chemoresistance in human glioblastoma.
    Biochemical and biophysical research communications, 2013, Nov-01, Volume: 440, Issue:4

    Topics: Antineoplastic Agents, Alkylating; Antineoplastic Agents, Phytogenic; Apoptosis; Brain Neoplasms; Ce

2013
Biliverdin reductase plays a crucial role in hypoxia-induced chemoresistance in human glioblastoma.
    Biochemical and biophysical research communications, 2013, Nov-01, Volume: 440, Issue:4

    Topics: Antineoplastic Agents, Alkylating; Antineoplastic Agents, Phytogenic; Apoptosis; Brain Neoplasms; Ce

2013
Biliverdin reductase plays a crucial role in hypoxia-induced chemoresistance in human glioblastoma.
    Biochemical and biophysical research communications, 2013, Nov-01, Volume: 440, Issue:4

    Topics: Antineoplastic Agents, Alkylating; Antineoplastic Agents, Phytogenic; Apoptosis; Brain Neoplasms; Ce

2013
Clinical course of central neurocytoma with malignant transformation-an indication for craniospinal irradiation.
    Pathology oncology research : POR, 2014, Volume: 20, Issue:2

    Topics: Adult; Brain Neoplasms; Cell Transformation, Neoplastic; Cerebrospinal Fluid; Chemotherapy, Adjuvant

2014
Clinical course of central neurocytoma with malignant transformation-an indication for craniospinal irradiation.
    Pathology oncology research : POR, 2014, Volume: 20, Issue:2

    Topics: Adult; Brain Neoplasms; Cell Transformation, Neoplastic; Cerebrospinal Fluid; Chemotherapy, Adjuvant

2014
Clinical course of central neurocytoma with malignant transformation-an indication for craniospinal irradiation.
    Pathology oncology research : POR, 2014, Volume: 20, Issue:2

    Topics: Adult; Brain Neoplasms; Cell Transformation, Neoplastic; Cerebrospinal Fluid; Chemotherapy, Adjuvant

2014
High expression of leptin receptor leads to temozolomide resistance with exhibiting stem/progenitor cell features in gliobalastoma.
    Cell cycle (Georgetown, Tex.), 2013, Dec-15, Volume: 12, Issue:24

    Topics: AC133 Antigen; Antigens, CD; Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cell Lin

2013
High expression of leptin receptor leads to temozolomide resistance with exhibiting stem/progenitor cell features in gliobalastoma.
    Cell cycle (Georgetown, Tex.), 2013, Dec-15, Volume: 12, Issue:24

    Topics: AC133 Antigen; Antigens, CD; Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cell Lin

2013
High expression of leptin receptor leads to temozolomide resistance with exhibiting stem/progenitor cell features in gliobalastoma.
    Cell cycle (Georgetown, Tex.), 2013, Dec-15, Volume: 12, Issue:24

    Topics: AC133 Antigen; Antigens, CD; Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cell Lin

2013
Factors associated with a higher rate of distant failure after primary treatment for glioblastoma.
    Journal of neuro-oncology, 2014, Volume: 116, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Disease Progression; DNA Modificati

2014
Factors associated with a higher rate of distant failure after primary treatment for glioblastoma.
    Journal of neuro-oncology, 2014, Volume: 116, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Disease Progression; DNA Modificati

2014
Factors associated with a higher rate of distant failure after primary treatment for glioblastoma.
    Journal of neuro-oncology, 2014, Volume: 116, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Disease Progression; DNA Modificati

2014
Retrospective analysis of bevacizumab in combination with ifosfamide, carboplatin, and etoposide in patients with second recurrence of glioblastoma.
    Neurologia medico-chirurgica, 2013, Volume: 53, Issue:11

    Topics: Adult; Aged; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Beva

2013
Retrospective analysis of bevacizumab in combination with ifosfamide, carboplatin, and etoposide in patients with second recurrence of glioblastoma.
    Neurologia medico-chirurgica, 2013, Volume: 53, Issue:11

    Topics: Adult; Aged; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Beva

2013
Retrospective analysis of bevacizumab in combination with ifosfamide, carboplatin, and etoposide in patients with second recurrence of glioblastoma.
    Neurologia medico-chirurgica, 2013, Volume: 53, Issue:11

    Topics: Adult; Aged; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Beva

2013
Treatment results of glioblastoma during the last 30 years in a single institute.
    Neurologia medico-chirurgica, 2013, Volume: 53, Issue:11

    Topics: Age Factors; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2013
Treatment results of glioblastoma during the last 30 years in a single institute.
    Neurologia medico-chirurgica, 2013, Volume: 53, Issue:11

    Topics: Age Factors; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2013
Treatment results of glioblastoma during the last 30 years in a single institute.
    Neurologia medico-chirurgica, 2013, Volume: 53, Issue:11

    Topics: Age Factors; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemothera

2013
Effectiveness of adjuvant temozolomide treatment in patients with glioblastoma.
    Neurosciences (Riyadh, Saudi Arabia), 2013, Volume: 18, Issue:4

    Topics: Aged; Antineoplastic Agents; Brain Neoplasms; Canada; Chemotherapy, Adjuvant; Dacarbazine; Female; G

2013
Effectiveness of adjuvant temozolomide treatment in patients with glioblastoma.
    Neurosciences (Riyadh, Saudi Arabia), 2013, Volume: 18, Issue:4

    Topics: Aged; Antineoplastic Agents; Brain Neoplasms; Canada; Chemotherapy, Adjuvant; Dacarbazine; Female; G

2013
Effectiveness of adjuvant temozolomide treatment in patients with glioblastoma.
    Neurosciences (Riyadh, Saudi Arabia), 2013, Volume: 18, Issue:4

    Topics: Aged; Antineoplastic Agents; Brain Neoplasms; Canada; Chemotherapy, Adjuvant; Dacarbazine; Female; G

2013
Inhibition of MMP14 potentiates the therapeutic effect of temozolomide and radiation in gliomas.
    Cancer medicine, 2013, Volume: 2, Issue:4

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Division; Cell Line, Tumor; Cell P

2013
Inhibition of MMP14 potentiates the therapeutic effect of temozolomide and radiation in gliomas.
    Cancer medicine, 2013, Volume: 2, Issue:4

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Division; Cell Line, Tumor; Cell P

2013
Inhibition of MMP14 potentiates the therapeutic effect of temozolomide and radiation in gliomas.
    Cancer medicine, 2013, Volume: 2, Issue:4

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Division; Cell Line, Tumor; Cell P

2013
Health-related quality of life and cognitive functioning in long-term anaplastic oligodendroglioma and oligoastrocytoma survivors.
    Journal of neuro-oncology, 2014, Volume: 116, Issue:1

    Topics: Aged; Astrocytoma; Brain Neoplasms; Cognition Disorders; Cohort Studies; Dacarbazine; DNA Modificati

2014
Health-related quality of life and cognitive functioning in long-term anaplastic oligodendroglioma and oligoastrocytoma survivors.
    Journal of neuro-oncology, 2014, Volume: 116, Issue:1

    Topics: Aged; Astrocytoma; Brain Neoplasms; Cognition Disorders; Cohort Studies; Dacarbazine; DNA Modificati

2014
Health-related quality of life and cognitive functioning in long-term anaplastic oligodendroglioma and oligoastrocytoma survivors.
    Journal of neuro-oncology, 2014, Volume: 116, Issue:1

    Topics: Aged; Astrocytoma; Brain Neoplasms; Cognition Disorders; Cohort Studies; Dacarbazine; DNA Modificati

2014
Combination of anti-VEGF therapy and temozolomide in two experimental human glioma models.
    Journal of neuro-oncology, 2014, Volume: 116, Issue:1

    Topics: Animals; Antibodies; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protoco

2014
Combination of anti-VEGF therapy and temozolomide in two experimental human glioma models.
    Journal of neuro-oncology, 2014, Volume: 116, Issue:1

    Topics: Animals; Antibodies; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protoco

2014
Combination of anti-VEGF therapy and temozolomide in two experimental human glioma models.
    Journal of neuro-oncology, 2014, Volume: 116, Issue:1

    Topics: Animals; Antibodies; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protoco

2014
Temporal relationship of post-operative radiotherapy with temozolomide and oncologic outcome for glioblastoma.
    Journal of neuro-oncology, 2014, Volume: 116, Issue:2

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cohort Studies; Dacarbazine; Female

2014
Temporal relationship of post-operative radiotherapy with temozolomide and oncologic outcome for glioblastoma.
    Journal of neuro-oncology, 2014, Volume: 116, Issue:2

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cohort Studies; Dacarbazine; Female

2014
Temporal relationship of post-operative radiotherapy with temozolomide and oncologic outcome for glioblastoma.
    Journal of neuro-oncology, 2014, Volume: 116, Issue:2

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cohort Studies; Dacarbazine; Female

2014
Cisplatin and temozolomide combination in the treatment of supratentorial anaplastic ependymoma.
    Chemotherapy, 2013, Volume: 59, Issue:3

    Topics: Antineoplastic Agents; Brain Neoplasms; Cisplatin; Dacarbazine; Drug Therapy, Combination; Ependymom

2013
Cisplatin and temozolomide combination in the treatment of supratentorial anaplastic ependymoma.
    Chemotherapy, 2013, Volume: 59, Issue:3

    Topics: Antineoplastic Agents; Brain Neoplasms; Cisplatin; Dacarbazine; Drug Therapy, Combination; Ependymom

2013
Cisplatin and temozolomide combination in the treatment of supratentorial anaplastic ependymoma.
    Chemotherapy, 2013, Volume: 59, Issue:3

    Topics: Antineoplastic Agents; Brain Neoplasms; Cisplatin; Dacarbazine; Drug Therapy, Combination; Ependymom

2013
Employment following chemoradiotherapy in glioblastoma: a prospective case series.
    Journal of cancer survivorship : research and practice, 2014, Volume: 8, Issue:1

    Topics: Adolescent; Adult; Aged; Brain Damage, Chronic; Brain Neoplasms; Chemoradiotherapy; Combined Modalit

2014
Employment following chemoradiotherapy in glioblastoma: a prospective case series.
    Journal of cancer survivorship : research and practice, 2014, Volume: 8, Issue:1

    Topics: Adolescent; Adult; Aged; Brain Damage, Chronic; Brain Neoplasms; Chemoradiotherapy; Combined Modalit

2014
Employment following chemoradiotherapy in glioblastoma: a prospective case series.
    Journal of cancer survivorship : research and practice, 2014, Volume: 8, Issue:1

    Topics: Adolescent; Adult; Aged; Brain Damage, Chronic; Brain Neoplasms; Chemoradiotherapy; Combined Modalit

2014
Treatment of newly diagnosed malignant glioma in the elderly people: new trials that impact therapy.
    International journal of clinical practice, 2013, Volume: 67, Issue:12

    Topics: Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Carmustine; Chemoradiotherapy; Dacarbazine

2013
Treatment of newly diagnosed malignant glioma in the elderly people: new trials that impact therapy.
    International journal of clinical practice, 2013, Volume: 67, Issue:12

    Topics: Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Carmustine; Chemoradiotherapy; Dacarbazine

2013
Treatment of newly diagnosed malignant glioma in the elderly people: new trials that impact therapy.
    International journal of clinical practice, 2013, Volume: 67, Issue:12

    Topics: Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Carmustine; Chemoradiotherapy; Dacarbazine

2013
Toxicity and outcome of radiotherapy with concomitant and adjuvant temozolomide in elderly patients with glioblastoma: a retrospective study.
    Neurologia medico-chirurgica, 2014, Volume: 54, Issue:4

    Topics: Age Factors; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradio

2014
Toxicity and outcome of radiotherapy with concomitant and adjuvant temozolomide in elderly patients with glioblastoma: a retrospective study.
    Neurologia medico-chirurgica, 2014, Volume: 54, Issue:4

    Topics: Age Factors; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradio

2014
Toxicity and outcome of radiotherapy with concomitant and adjuvant temozolomide in elderly patients with glioblastoma: a retrospective study.
    Neurologia medico-chirurgica, 2014, Volume: 54, Issue:4

    Topics: Age Factors; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradio

2014
Central neurotoxicity of standard treatment in patients with newly-diagnosed high-grade glioma: a prospective longitudinal study.
    Journal of neuro-oncology, 2014, Volume: 116, Issue:2

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Atrophy; Brain Neoplasms; Cerebral Corte

2014
Central neurotoxicity of standard treatment in patients with newly-diagnosed high-grade glioma: a prospective longitudinal study.
    Journal of neuro-oncology, 2014, Volume: 116, Issue:2

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Atrophy; Brain Neoplasms; Cerebral Corte

2014
Central neurotoxicity of standard treatment in patients with newly-diagnosed high-grade glioma: a prospective longitudinal study.
    Journal of neuro-oncology, 2014, Volume: 116, Issue:2

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Atrophy; Brain Neoplasms; Cerebral Corte

2014
Is there pseudoprogression in secondary glioblastomas?
    International journal of radiation oncology, biology, physics, 2013, Dec-01, Volume: 87, Issue:5

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy, Adjuvant; Chromo

2013
Is there pseudoprogression in secondary glioblastomas?
    International journal of radiation oncology, biology, physics, 2013, Dec-01, Volume: 87, Issue:5

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy, Adjuvant; Chromo

2013
Is there pseudoprogression in secondary glioblastomas?
    International journal of radiation oncology, biology, physics, 2013, Dec-01, Volume: 87, Issue:5

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy, Adjuvant; Chromo

2013
Evaluation of post-operative complications associated with repeat resection and BCNU wafer implantation in recurrent glioblastoma.
    Acta neurochirurgica, 2014, Volume: 156, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Carmustine; Comb

2014
Evaluation of post-operative complications associated with repeat resection and BCNU wafer implantation in recurrent glioblastoma.
    Acta neurochirurgica, 2014, Volume: 156, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Carmustine; Comb

2014
Evaluation of post-operative complications associated with repeat resection and BCNU wafer implantation in recurrent glioblastoma.
    Acta neurochirurgica, 2014, Volume: 156, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Carmustine; Comb

2014
Temozolomide-related acute lymphoblastic leukemia with translocation (4;11)(q21;q23) in a glioblastoma patient.
    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2014, Volume: 21, Issue:4

    Topics: Antineoplastic Agents, Alkylating; Bone Marrow; Brain Neoplasms; Cytogenetic Analysis; Dacarbazine;

2014
Temozolomide-related acute lymphoblastic leukemia with translocation (4;11)(q21;q23) in a glioblastoma patient.
    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2014, Volume: 21, Issue:4

    Topics: Antineoplastic Agents, Alkylating; Bone Marrow; Brain Neoplasms; Cytogenetic Analysis; Dacarbazine;

2014
Temozolomide-related acute lymphoblastic leukemia with translocation (4;11)(q21;q23) in a glioblastoma patient.
    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2014, Volume: 21, Issue:4

    Topics: Antineoplastic Agents, Alkylating; Bone Marrow; Brain Neoplasms; Cytogenetic Analysis; Dacarbazine;

2014
Inhibition of elongation factor-2 kinase augments the antitumor activity of Temozolomide against glioma.
    PloS one, 2013, Volume: 8, Issue:11

    Topics: Animals; Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cell Movem

2013
Inhibition of elongation factor-2 kinase augments the antitumor activity of Temozolomide against glioma.
    PloS one, 2013, Volume: 8, Issue:11

    Topics: Animals; Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cell Movem

2013
Inhibition of elongation factor-2 kinase augments the antitumor activity of Temozolomide against glioma.
    PloS one, 2013, Volume: 8, Issue:11

    Topics: Animals; Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cell Movem

2013
Increased sensitivity to radiochemotherapy in IDH1 mutant glioblastoma as demonstrated by serial quantitative MR volumetry.
    Neuro-oncology, 2014, Volume: 16, Issue:3

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Dacarbazine; Glioblastoma; Hu

2014
Increased sensitivity to radiochemotherapy in IDH1 mutant glioblastoma as demonstrated by serial quantitative MR volumetry.
    Neuro-oncology, 2014, Volume: 16, Issue:3

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Dacarbazine; Glioblastoma; Hu

2014
Increased sensitivity to radiochemotherapy in IDH1 mutant glioblastoma as demonstrated by serial quantitative MR volumetry.
    Neuro-oncology, 2014, Volume: 16, Issue:3

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Dacarbazine; Glioblastoma; Hu

2014
Response of primary glioblastoma cells to therapy is patient specific and independent of cancer stem cell phenotype.
    Neuro-oncology, 2014, Volume: 16, Issue:3

    Topics: AC133 Antigen; Antigens, CD; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Survival; Chem

2014
Response of primary glioblastoma cells to therapy is patient specific and independent of cancer stem cell phenotype.
    Neuro-oncology, 2014, Volume: 16, Issue:3

    Topics: AC133 Antigen; Antigens, CD; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Survival; Chem

2014
Response of primary glioblastoma cells to therapy is patient specific and independent of cancer stem cell phenotype.
    Neuro-oncology, 2014, Volume: 16, Issue:3

    Topics: AC133 Antigen; Antigens, CD; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Survival; Chem

2014
Lobarstin enhances chemosensitivity in human glioblastoma T98G cells.
    Anticancer research, 2013, Volume: 33, Issue:12

    Topics: Antineoplastic Agents; Base Sequence; Benzofurans; Brain Neoplasms; Cell Line, Tumor; Comet Assay; D

2013
Lobarstin enhances chemosensitivity in human glioblastoma T98G cells.
    Anticancer research, 2013, Volume: 33, Issue:12

    Topics: Antineoplastic Agents; Base Sequence; Benzofurans; Brain Neoplasms; Cell Line, Tumor; Comet Assay; D

2013
Lobarstin enhances chemosensitivity in human glioblastoma T98G cells.
    Anticancer research, 2013, Volume: 33, Issue:12

    Topics: Antineoplastic Agents; Base Sequence; Benzofurans; Brain Neoplasms; Cell Line, Tumor; Comet Assay; D

2013
Mechanism of temozolomide-induced antitumour effects on glioma cells.
    The Journal of international medical research, 2014, Volume: 42, Issue:1

    Topics: Antineoplastic Agents; Apoptosis; Brain Neoplasms; Cell Cycle; Dacarbazine; Flow Cytometry; Glioma;

2014
Mechanism of temozolomide-induced antitumour effects on glioma cells.
    The Journal of international medical research, 2014, Volume: 42, Issue:1

    Topics: Antineoplastic Agents; Apoptosis; Brain Neoplasms; Cell Cycle; Dacarbazine; Flow Cytometry; Glioma;

2014
Mechanism of temozolomide-induced antitumour effects on glioma cells.
    The Journal of international medical research, 2014, Volume: 42, Issue:1

    Topics: Antineoplastic Agents; Apoptosis; Brain Neoplasms; Cell Cycle; Dacarbazine; Flow Cytometry; Glioma;

2014
Mutational analysis reveals the origin and therapy-driven evolution of recurrent glioma.
    Science (New York, N.Y.), 2014, Jan-10, Volume: 343, Issue:6167

    Topics: Antineoplastic Agents, Alkylating; Brain; Brain Neoplasms; Dacarbazine; DNA Helicases; DNA Mutationa

2014
Mutational analysis reveals the origin and therapy-driven evolution of recurrent glioma.
    Science (New York, N.Y.), 2014, Jan-10, Volume: 343, Issue:6167

    Topics: Antineoplastic Agents, Alkylating; Brain; Brain Neoplasms; Dacarbazine; DNA Helicases; DNA Mutationa

2014
Mutational analysis reveals the origin and therapy-driven evolution of recurrent glioma.
    Science (New York, N.Y.), 2014, Jan-10, Volume: 343, Issue:6167

    Topics: Antineoplastic Agents, Alkylating; Brain; Brain Neoplasms; Dacarbazine; DNA Helicases; DNA Mutationa

2014
Concomitant treatment with pertussis toxin plus temozolomide increases the survival of rats bearing intracerebral RG2 glioma.
    Journal of cancer research and clinical oncology, 2014, Volume: 140, Issue:2

    Topics: Animals; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Apoptosi

2014
Concomitant treatment with pertussis toxin plus temozolomide increases the survival of rats bearing intracerebral RG2 glioma.
    Journal of cancer research and clinical oncology, 2014, Volume: 140, Issue:2

    Topics: Animals; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Apoptosi

2014
Concomitant treatment with pertussis toxin plus temozolomide increases the survival of rats bearing intracerebral RG2 glioma.
    Journal of cancer research and clinical oncology, 2014, Volume: 140, Issue:2

    Topics: Animals; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Apoptosi

2014
[Results of postoperative radiochemotherapy of glioblastoma multiforme].
    Magyar onkologia, 2013, Volume: 57, Issue:4

    Topics: Adult; Aged; Antineoplastic Agents; Brain Neoplasms; Chemoradiotherapy, Adjuvant; Dacarbazine; Disea

2013
[Results of postoperative radiochemotherapy of glioblastoma multiforme].
    Magyar onkologia, 2013, Volume: 57, Issue:4

    Topics: Adult; Aged; Antineoplastic Agents; Brain Neoplasms; Chemoradiotherapy, Adjuvant; Dacarbazine; Disea

2013
[Results of postoperative radiochemotherapy of glioblastoma multiforme].
    Magyar onkologia, 2013, Volume: 57, Issue:4

    Topics: Adult; Aged; Antineoplastic Agents; Brain Neoplasms; Chemoradiotherapy, Adjuvant; Dacarbazine; Disea

2013
[Our experience with targeted therapy in glioblastoma multiforme].
    Magyar onkologia, 2013, Volume: 57, Issue:4

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humaniz

2013
[Our experience with targeted therapy in glioblastoma multiforme].
    Magyar onkologia, 2013, Volume: 57, Issue:4

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humaniz

2013
[Our experience with targeted therapy in glioblastoma multiforme].
    Magyar onkologia, 2013, Volume: 57, Issue:4

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humaniz

2013
Local delivery of angiogenesis-inhibitor minocycline combined with radiotherapy and oral temozolomide chemotherapy in 9L glioma.
    Journal of neurosurgery, 2014, Volume: 120, Issue:3

    Topics: Administration, Oral; Angiogenesis Inhibitors; Animals; Antineoplastic Agents, Alkylating; Brain Neo

2014
Local delivery of angiogenesis-inhibitor minocycline combined with radiotherapy and oral temozolomide chemotherapy in 9L glioma.
    Journal of neurosurgery, 2014, Volume: 120, Issue:3

    Topics: Administration, Oral; Angiogenesis Inhibitors; Animals; Antineoplastic Agents, Alkylating; Brain Neo

2014
Local delivery of angiogenesis-inhibitor minocycline combined with radiotherapy and oral temozolomide chemotherapy in 9L glioma.
    Journal of neurosurgery, 2014, Volume: 120, Issue:3

    Topics: Administration, Oral; Angiogenesis Inhibitors; Animals; Antineoplastic Agents, Alkylating; Brain Neo

2014
EGFR wild type antagonizes EGFRvIII-mediated activation of Met in glioblastoma.
    Oncogene, 2015, Jan-02, Volume: 34, Issue:1

    Topics: Brain Neoplasms; Cell Line, Tumor; Dacarbazine; Epidermal Growth Factor; ErbB Receptors; Gene Expres

2015
EGFR wild type antagonizes EGFRvIII-mediated activation of Met in glioblastoma.
    Oncogene, 2015, Jan-02, Volume: 34, Issue:1

    Topics: Brain Neoplasms; Cell Line, Tumor; Dacarbazine; Epidermal Growth Factor; ErbB Receptors; Gene Expres

2015
EGFR wild type antagonizes EGFRvIII-mediated activation of Met in glioblastoma.
    Oncogene, 2015, Jan-02, Volume: 34, Issue:1

    Topics: Brain Neoplasms; Cell Line, Tumor; Dacarbazine; Epidermal Growth Factor; ErbB Receptors; Gene Expres

2015
Extraneural metastases of anaplastic oligodendroglioma.
    APMIS : acta pathologica, microbiologica, et immunologica Scandinavica, 2014, Volume: 122, Issue:7

    Topics: Antineoplastic Agents, Alkylating; Bone Neoplasms; Brain Neoplasms; Dacarbazine; Humans; Lymphatic M

2014
Extraneural metastases of anaplastic oligodendroglioma.
    APMIS : acta pathologica, microbiologica, et immunologica Scandinavica, 2014, Volume: 122, Issue:7

    Topics: Antineoplastic Agents, Alkylating; Bone Neoplasms; Brain Neoplasms; Dacarbazine; Humans; Lymphatic M

2014
Extraneural metastases of anaplastic oligodendroglioma.
    APMIS : acta pathologica, microbiologica, et immunologica Scandinavica, 2014, Volume: 122, Issue:7

    Topics: Antineoplastic Agents, Alkylating; Bone Neoplasms; Brain Neoplasms; Dacarbazine; Humans; Lymphatic M

2014
Vemurafenib in pediatric patients with BRAFV600E mutated high-grade gliomas.
    Pediatric blood & cancer, 2014, Volume: 61, Issue:6

    Topics: Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Proto

2014
Vemurafenib in pediatric patients with BRAFV600E mutated high-grade gliomas.
    Pediatric blood & cancer, 2014, Volume: 61, Issue:6

    Topics: Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Proto

2014
Vemurafenib in pediatric patients with BRAFV600E mutated high-grade gliomas.
    Pediatric blood & cancer, 2014, Volume: 61, Issue:6

    Topics: Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Proto

2014
Concomitant viral and bacterial encephalitis after temozolomide for glioblastoma.
    The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques, 2014, Volume: 41, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Encephalitis, Viral; Glioblastoma;

2014
Concomitant viral and bacterial encephalitis after temozolomide for glioblastoma.
    The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques, 2014, Volume: 41, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Encephalitis, Viral; Glioblastoma;

2014
Concomitant viral and bacterial encephalitis after temozolomide for glioblastoma.
    The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques, 2014, Volume: 41, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Encephalitis, Viral; Glioblastoma;

2014
A fatal case of acute interstitial pneumonia (AIP) in a woman affected by glioblastoma.
    Current drug safety, 2014, Volume: 9, Issue:1

    Topics: Aged; Antineoplastic Agents, Alkylating; Blood Gas Analysis; Brain Neoplasms; Bronchoalveolar Lavage

2014
A fatal case of acute interstitial pneumonia (AIP) in a woman affected by glioblastoma.
    Current drug safety, 2014, Volume: 9, Issue:1

    Topics: Aged; Antineoplastic Agents, Alkylating; Blood Gas Analysis; Brain Neoplasms; Bronchoalveolar Lavage

2014
A fatal case of acute interstitial pneumonia (AIP) in a woman affected by glioblastoma.
    Current drug safety, 2014, Volume: 9, Issue:1

    Topics: Aged; Antineoplastic Agents, Alkylating; Blood Gas Analysis; Brain Neoplasms; Bronchoalveolar Lavage

2014
Improved hippocampal dose with reduced margin radiotherapy for glioblastoma multiforme.
    Radiation oncology (London, England), 2014, Jan-10, Volume: 9

    Topics: Brain Neoplasms; Chemoradiotherapy; Chemotherapy, Adjuvant; Clinical Trials, Phase III as Topic; Dac

2014
Improved hippocampal dose with reduced margin radiotherapy for glioblastoma multiforme.
    Radiation oncology (London, England), 2014, Jan-10, Volume: 9

    Topics: Brain Neoplasms; Chemoradiotherapy; Chemotherapy, Adjuvant; Clinical Trials, Phase III as Topic; Dac

2014
Improved hippocampal dose with reduced margin radiotherapy for glioblastoma multiforme.
    Radiation oncology (London, England), 2014, Jan-10, Volume: 9

    Topics: Brain Neoplasms; Chemoradiotherapy; Chemotherapy, Adjuvant; Clinical Trials, Phase III as Topic; Dac

2014
Enhanced cytotoxic effect of radiation and temozolomide in malignant glioma cells: targeting PI3K-AKT-mTOR signaling, HSP90 and histone deacetylases.
    BMC cancer, 2014, Jan-13, Volume: 14

    Topics: Antineoplastic Agents, Alkylating; Apoptosis; Autophagy; Brain Neoplasms; Cell Line, Tumor; Cell Mov

2014
Enhanced cytotoxic effect of radiation and temozolomide in malignant glioma cells: targeting PI3K-AKT-mTOR signaling, HSP90 and histone deacetylases.
    BMC cancer, 2014, Jan-13, Volume: 14

    Topics: Antineoplastic Agents, Alkylating; Apoptosis; Autophagy; Brain Neoplasms; Cell Line, Tumor; Cell Mov

2014
Enhanced cytotoxic effect of radiation and temozolomide in malignant glioma cells: targeting PI3K-AKT-mTOR signaling, HSP90 and histone deacetylases.
    BMC cancer, 2014, Jan-13, Volume: 14

    Topics: Antineoplastic Agents, Alkylating; Apoptosis; Autophagy; Brain Neoplasms; Cell Line, Tumor; Cell Mov

2014
Outcome-based determination of optimal pyrosequencing assay for MGMT methylation detection in glioblastoma patients.
    Journal of neuro-oncology, 2014, Volume: 116, Issue:3

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cohort Studies; Dacarbazine; Disease Notificatio

2014
Outcome-based determination of optimal pyrosequencing assay for MGMT methylation detection in glioblastoma patients.
    Journal of neuro-oncology, 2014, Volume: 116, Issue:3

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cohort Studies; Dacarbazine; Disease Notificatio

2014
Outcome-based determination of optimal pyrosequencing assay for MGMT methylation detection in glioblastoma patients.
    Journal of neuro-oncology, 2014, Volume: 116, Issue:3

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cohort Studies; Dacarbazine; Disease Notificatio

2014
Synergistic inhibition of angiogenesis and glioma cell-induced angiogenesis by the combination of temozolomide and enediyne antibiotic lidamycin.
    Cancer biology & therapy, 2014, Volume: 15, Issue:4

    Topics: Aminoglycosides; Angiogenesis Inhibitors; Animals; Anti-Bacterial Agents; Apoptosis; Brain; Brain Ne

2014
Synergistic inhibition of angiogenesis and glioma cell-induced angiogenesis by the combination of temozolomide and enediyne antibiotic lidamycin.
    Cancer biology & therapy, 2014, Volume: 15, Issue:4

    Topics: Aminoglycosides; Angiogenesis Inhibitors; Animals; Anti-Bacterial Agents; Apoptosis; Brain; Brain Ne

2014
Synergistic inhibition of angiogenesis and glioma cell-induced angiogenesis by the combination of temozolomide and enediyne antibiotic lidamycin.
    Cancer biology & therapy, 2014, Volume: 15, Issue:4

    Topics: Aminoglycosides; Angiogenesis Inhibitors; Animals; Anti-Bacterial Agents; Apoptosis; Brain; Brain Ne

2014
Potential application of temozolomide in mesenchymal stem cell-based TRAIL gene therapy against malignant glioma.
    Stem cells translational medicine, 2014, Volume: 3, Issue:2

    Topics: Adult; Animals; Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Dac

2014
Potential application of temozolomide in mesenchymal stem cell-based TRAIL gene therapy against malignant glioma.
    Stem cells translational medicine, 2014, Volume: 3, Issue:2

    Topics: Adult; Animals; Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Dac

2014
Potential application of temozolomide in mesenchymal stem cell-based TRAIL gene therapy against malignant glioma.
    Stem cells translational medicine, 2014, Volume: 3, Issue:2

    Topics: Adult; Animals; Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Dac

2014
Hyperdiploid tumor cells increase phenotypic heterogeneity within Glioblastoma tumors.
    Molecular bioSystems, 2014, Volume: 10, Issue:4

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Division; Cell Proliferation; Daca

2014
Hyperdiploid tumor cells increase phenotypic heterogeneity within Glioblastoma tumors.
    Molecular bioSystems, 2014, Volume: 10, Issue:4

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Division; Cell Proliferation; Daca

2014
Hyperdiploid tumor cells increase phenotypic heterogeneity within Glioblastoma tumors.
    Molecular bioSystems, 2014, Volume: 10, Issue:4

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Division; Cell Proliferation; Daca

2014
Large volume reirradiation as salvage therapy for glioblastoma after progression on bevacizumab.
    Journal of neuro-oncology, 2014, Volume: 117, Issue:1

    Topics: Adult; Aged; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Antineoplastic Agents, Alky

2014
Large volume reirradiation as salvage therapy for glioblastoma after progression on bevacizumab.
    Journal of neuro-oncology, 2014, Volume: 117, Issue:1

    Topics: Adult; Aged; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Antineoplastic Agents, Alky

2014
Large volume reirradiation as salvage therapy for glioblastoma after progression on bevacizumab.
    Journal of neuro-oncology, 2014, Volume: 117, Issue:1

    Topics: Adult; Aged; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Antineoplastic Agents, Alky

2014
Factors impacting survival following second surgery in patients with glioblastoma in the temozolomide treatment era, incorporating neutrophil/lymphocyte ratio and time to first progression.
    Journal of neuro-oncology, 2014, Volume: 117, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Fem

2014
Factors impacting survival following second surgery in patients with glioblastoma in the temozolomide treatment era, incorporating neutrophil/lymphocyte ratio and time to first progression.
    Journal of neuro-oncology, 2014, Volume: 117, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Fem

2014
Factors impacting survival following second surgery in patients with glioblastoma in the temozolomide treatment era, incorporating neutrophil/lymphocyte ratio and time to first progression.
    Journal of neuro-oncology, 2014, Volume: 117, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Fem

2014
Conditional probability of survival and post-progression survival in patients with glioblastoma in the temozolomide treatment era.
    Journal of neuro-oncology, 2014, Volume: 117, Issue:1

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Antineoplastic Combin

2014
Conditional probability of survival and post-progression survival in patients with glioblastoma in the temozolomide treatment era.
    Journal of neuro-oncology, 2014, Volume: 117, Issue:1

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Antineoplastic Combin

2014
Conditional probability of survival and post-progression survival in patients with glioblastoma in the temozolomide treatment era.
    Journal of neuro-oncology, 2014, Volume: 117, Issue:1

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Antineoplastic Combin

2014
The adherens junction-associated protein 1 is a negative transcriptional regulator of MAGEA2, which potentiates temozolomide-induced apoptosis in GBM.
    International journal of oncology, 2014, Volume: 44, Issue:4

    Topics: Adherens Junctions; Antineoplastic Agents, Alkylating; Apoptosis; bcl-2-Associated X Protein; Brain

2014
The adherens junction-associated protein 1 is a negative transcriptional regulator of MAGEA2, which potentiates temozolomide-induced apoptosis in GBM.
    International journal of oncology, 2014, Volume: 44, Issue:4

    Topics: Adherens Junctions; Antineoplastic Agents, Alkylating; Apoptosis; bcl-2-Associated X Protein; Brain

2014
The adherens junction-associated protein 1 is a negative transcriptional regulator of MAGEA2, which potentiates temozolomide-induced apoptosis in GBM.
    International journal of oncology, 2014, Volume: 44, Issue:4

    Topics: Adherens Junctions; Antineoplastic Agents, Alkylating; Apoptosis; bcl-2-Associated X Protein; Brain

2014
EFEMP1 induces γ-secretase/Notch-mediated temozolomide resistance in glioblastoma.
    Oncotarget, 2014, Jan-30, Volume: 5, Issue:2

    Topics: Amyloid Precursor Protein Secretases; Animals; Antineoplastic Agents, Alkylating; Antineoplastic Com

2014
EFEMP1 induces γ-secretase/Notch-mediated temozolomide resistance in glioblastoma.
    Oncotarget, 2014, Jan-30, Volume: 5, Issue:2

    Topics: Amyloid Precursor Protein Secretases; Animals; Antineoplastic Agents, Alkylating; Antineoplastic Com

2014
EFEMP1 induces γ-secretase/Notch-mediated temozolomide resistance in glioblastoma.
    Oncotarget, 2014, Jan-30, Volume: 5, Issue:2

    Topics: Amyloid Precursor Protein Secretases; Animals; Antineoplastic Agents, Alkylating; Antineoplastic Com

2014
Initial and cumulative recurrence patterns of glioblastoma after temozolomide-based chemoradiotherapy and salvage treatment: a retrospective cohort study in a single institution.
    Radiation oncology (London, England), 2013, Apr-23, Volume: 8

    Topics: Adult; Aged; Antineoplastic Agents; Brain Neoplasms; Chemoradiotherapy; Cohort Studies; Dacarbazine;

2013
Initial and cumulative recurrence patterns of glioblastoma after temozolomide-based chemoradiotherapy and salvage treatment: a retrospective cohort study in a single institution.
    Radiation oncology (London, England), 2013, Apr-23, Volume: 8

    Topics: Adult; Aged; Antineoplastic Agents; Brain Neoplasms; Chemoradiotherapy; Cohort Studies; Dacarbazine;

2013
Initial and cumulative recurrence patterns of glioblastoma after temozolomide-based chemoradiotherapy and salvage treatment: a retrospective cohort study in a single institution.
    Radiation oncology (London, England), 2013, Apr-23, Volume: 8

    Topics: Adult; Aged; Antineoplastic Agents; Brain Neoplasms; Chemoradiotherapy; Cohort Studies; Dacarbazine;

2013
Temozolomide does not impair gene therapy-mediated antitumor immunity in syngeneic brain tumor models.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2014, Mar-15, Volume: 20, Issue:6

    Topics: Adenoviridae; Animals; Antineoplastic Agents; Brain Neoplasms; Dacarbazine; Disease Models, Animal;

2014
Temozolomide does not impair gene therapy-mediated antitumor immunity in syngeneic brain tumor models.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2014, Mar-15, Volume: 20, Issue:6

    Topics: Adenoviridae; Animals; Antineoplastic Agents; Brain Neoplasms; Dacarbazine; Disease Models, Animal;

2014
Temozolomide does not impair gene therapy-mediated antitumor immunity in syngeneic brain tumor models.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2014, Mar-15, Volume: 20, Issue:6

    Topics: Adenoviridae; Animals; Antineoplastic Agents; Brain Neoplasms; Dacarbazine; Disease Models, Animal;

2014
Asparagine depletion potentiates the cytotoxic effect of chemotherapy against brain tumors.
    Molecular cancer research : MCR, 2014, Volume: 12, Issue:5

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Asparagine; Aspartate-Ammonia

2014
Asparagine depletion potentiates the cytotoxic effect of chemotherapy against brain tumors.
    Molecular cancer research : MCR, 2014, Volume: 12, Issue:5

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Asparagine; Aspartate-Ammonia

2014
Asparagine depletion potentiates the cytotoxic effect of chemotherapy against brain tumors.
    Molecular cancer research : MCR, 2014, Volume: 12, Issue:5

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Asparagine; Aspartate-Ammonia

2014
[Management of patients with metastatic cutaneous melanoma: French national guidelines. French National Cancer Institute].
    Annales de dermatologie et de venereologie, 2014, Volume: 141, Issue:2

    Topics: Antibodies, Monoclonal; Antineoplastic Agents; Bone Neoplasms; Brain Neoplasms; Combined Modality Th

2014
[Management of patients with metastatic cutaneous melanoma: French national guidelines. French National Cancer Institute].
    Annales de dermatologie et de venereologie, 2014, Volume: 141, Issue:2

    Topics: Antibodies, Monoclonal; Antineoplastic Agents; Bone Neoplasms; Brain Neoplasms; Combined Modality Th

2014
[Management of patients with metastatic cutaneous melanoma: French national guidelines. French National Cancer Institute].
    Annales de dermatologie et de venereologie, 2014, Volume: 141, Issue:2

    Topics: Antibodies, Monoclonal; Antineoplastic Agents; Bone Neoplasms; Brain Neoplasms; Combined Modality Th

2014
MGMT promoter methylation in plasma of glioma patients receiving temozolomide.
    Journal of neuro-oncology, 2014, Volume: 117, Issue:2

    Topics: Aged; Antineoplastic Agents, Alkylating; Biomarkers, Tumor; Brain Neoplasms; Dacarbazine; Disease-Fr

2014
MGMT promoter methylation in plasma of glioma patients receiving temozolomide.
    Journal of neuro-oncology, 2014, Volume: 117, Issue:2

    Topics: Aged; Antineoplastic Agents, Alkylating; Biomarkers, Tumor; Brain Neoplasms; Dacarbazine; Disease-Fr

2014
MGMT promoter methylation in plasma of glioma patients receiving temozolomide.
    Journal of neuro-oncology, 2014, Volume: 117, Issue:2

    Topics: Aged; Antineoplastic Agents, Alkylating; Biomarkers, Tumor; Brain Neoplasms; Dacarbazine; Disease-Fr

2014
Bevacizumab in glioblastoma--still much to learn.
    The New England journal of medicine, 2014, Feb-20, Volume: 370, Issue:8

    Topics: Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Bevacizumab; Brain Neoplasms; Dacarbazin

2014
Bevacizumab in glioblastoma--still much to learn.
    The New England journal of medicine, 2014, Feb-20, Volume: 370, Issue:8

    Topics: Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Bevacizumab; Brain Neoplasms; Dacarbazin

2014
Bevacizumab in glioblastoma--still much to learn.
    The New England journal of medicine, 2014, Feb-20, Volume: 370, Issue:8

    Topics: Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Bevacizumab; Brain Neoplasms; Dacarbazin

2014
Outcome of conventional treatment and prognostic factor in elderly glioblastoma patients.
    Acta neurochirurgica, 2014, Volume: 156, Issue:4

    Topics: Adult; Age Factors; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Che

2014
Outcome of conventional treatment and prognostic factor in elderly glioblastoma patients.
    Acta neurochirurgica, 2014, Volume: 156, Issue:4

    Topics: Adult; Age Factors; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Che

2014
Outcome of conventional treatment and prognostic factor in elderly glioblastoma patients.
    Acta neurochirurgica, 2014, Volume: 156, Issue:4

    Topics: Adult; Age Factors; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Che

2014
The NFκB inhibitor, SN50, induces differentiation of glioma stem cells and suppresses their oncogenic phenotype.
    Cancer biology & therapy, 2014, Volume: 15, Issue:5

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Differentiation; Dacarbazine; Drug

2014
The NFκB inhibitor, SN50, induces differentiation of glioma stem cells and suppresses their oncogenic phenotype.
    Cancer biology & therapy, 2014, Volume: 15, Issue:5

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Differentiation; Dacarbazine; Drug

2014
The NFκB inhibitor, SN50, induces differentiation of glioma stem cells and suppresses their oncogenic phenotype.
    Cancer biology & therapy, 2014, Volume: 15, Issue:5

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Differentiation; Dacarbazine; Drug

2014
miR-181 subunits enhance the chemosensitivity of temozolomide by Rap1B-mediated cytoskeleton remodeling in glioblastoma cells.
    Medical oncology (Northwood, London, England), 2014, Volume: 31, Issue:4

    Topics: Actins; Antineoplastic Agents, Alkylating; Base Sequence; Brain Neoplasms; Cell Line, Tumor; Cell Mo

2014
miR-181 subunits enhance the chemosensitivity of temozolomide by Rap1B-mediated cytoskeleton remodeling in glioblastoma cells.
    Medical oncology (Northwood, London, England), 2014, Volume: 31, Issue:4

    Topics: Actins; Antineoplastic Agents, Alkylating; Base Sequence; Brain Neoplasms; Cell Line, Tumor; Cell Mo

2014
miR-181 subunits enhance the chemosensitivity of temozolomide by Rap1B-mediated cytoskeleton remodeling in glioblastoma cells.
    Medical oncology (Northwood, London, England), 2014, Volume: 31, Issue:4

    Topics: Actins; Antineoplastic Agents, Alkylating; Base Sequence; Brain Neoplasms; Cell Line, Tumor; Cell Mo

2014
Patterns of care and survival of glioblastoma patients: a comparative study between 2004 and 2008 in Lyon, France.
    Revue neurologique, 2014, Volume: 170, Issue:3

    Topics: Aged; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Bevacizumab

2014
Patterns of care and survival of glioblastoma patients: a comparative study between 2004 and 2008 in Lyon, France.
    Revue neurologique, 2014, Volume: 170, Issue:3

    Topics: Aged; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Bevacizumab

2014
Patterns of care and survival of glioblastoma patients: a comparative study between 2004 and 2008 in Lyon, France.
    Revue neurologique, 2014, Volume: 170, Issue:3

    Topics: Aged; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Bevacizumab

2014
BRAF-V600 mutations have no prognostic impact in stage IV melanoma patients treated with monochemotherapy.
    PloS one, 2014, Volume: 9, Issue:2

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Female; Follow-Up Stud

2014
BRAF-V600 mutations have no prognostic impact in stage IV melanoma patients treated with monochemotherapy.
    PloS one, 2014, Volume: 9, Issue:2

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Female; Follow-Up Stud

2014
BRAF-V600 mutations have no prognostic impact in stage IV melanoma patients treated with monochemotherapy.
    PloS one, 2014, Volume: 9, Issue:2

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Female; Follow-Up Stud

2014
Quantitative metabolome analysis profiles activation of glutaminolysis in glioma with IDH1 mutation.
    Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine, 2014, Volume: 35, Issue:6

    Topics: Brain Neoplasms; Cell Line, Tumor; Dacarbazine; Glioma; Glutaminase; Glutamine; Glutarates; HEK293 C

2014
Quantitative metabolome analysis profiles activation of glutaminolysis in glioma with IDH1 mutation.
    Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine, 2014, Volume: 35, Issue:6

    Topics: Brain Neoplasms; Cell Line, Tumor; Dacarbazine; Glioma; Glutaminase; Glutamine; Glutarates; HEK293 C

2014
Quantitative metabolome analysis profiles activation of glutaminolysis in glioma with IDH1 mutation.
    Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine, 2014, Volume: 35, Issue:6

    Topics: Brain Neoplasms; Cell Line, Tumor; Dacarbazine; Glioma; Glutaminase; Glutamine; Glutarates; HEK293 C

2014
Analysis of salivary fluid and chemosensory functions in patients treated for primary malignant brain tumors.
    Clinical oral investigations, 2015, Volume: 19, Issue:1

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Case-Control Studies; Combined Moda

2015
Analysis of salivary fluid and chemosensory functions in patients treated for primary malignant brain tumors.
    Clinical oral investigations, 2015, Volume: 19, Issue:1

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Case-Control Studies; Combined Moda

2015
Analysis of salivary fluid and chemosensory functions in patients treated for primary malignant brain tumors.
    Clinical oral investigations, 2015, Volume: 19, Issue:1

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Case-Control Studies; Combined Moda

2015
Conversion of differentiated cancer cells into cancer stem-like cells in a glioblastoma model after primary chemotherapy.
    Cell death and differentiation, 2014, Volume: 21, Issue:7

    Topics: Animals; Antineoplastic Agents, Alkylating; Basic Helix-Loop-Helix Transcription Factors; Brain Neop

2014
Conversion of differentiated cancer cells into cancer stem-like cells in a glioblastoma model after primary chemotherapy.
    Cell death and differentiation, 2014, Volume: 21, Issue:7

    Topics: Animals; Antineoplastic Agents, Alkylating; Basic Helix-Loop-Helix Transcription Factors; Brain Neop

2014
Conversion of differentiated cancer cells into cancer stem-like cells in a glioblastoma model after primary chemotherapy.
    Cell death and differentiation, 2014, Volume: 21, Issue:7

    Topics: Animals; Antineoplastic Agents, Alkylating; Basic Helix-Loop-Helix Transcription Factors; Brain Neop

2014
Odds of death after glioblastoma diagnosis in the United States by chemotherapeutic era.
    Cancer medicine, 2014, Volume: 3, Issue:3

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antibodies, Monoclonal, Humanized; Bevacizumab; Brain Ne

2014
Odds of death after glioblastoma diagnosis in the United States by chemotherapeutic era.
    Cancer medicine, 2014, Volume: 3, Issue:3

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antibodies, Monoclonal, Humanized; Bevacizumab; Brain Ne

2014
Odds of death after glioblastoma diagnosis in the United States by chemotherapeutic era.
    Cancer medicine, 2014, Volume: 3, Issue:3

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antibodies, Monoclonal, Humanized; Bevacizumab; Brain Ne

2014
In vivo chemical exchange saturation transfer imaging allows early detection of a therapeutic response in glioblastoma.
    Proceedings of the National Academy of Sciences of the United States of America, 2014, Mar-25, Volume: 111, Issue:12

    Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Dacarbazine; Glioblastoma; Humans; Mice; Mice, SCID

2014
In vivo chemical exchange saturation transfer imaging allows early detection of a therapeutic response in glioblastoma.
    Proceedings of the National Academy of Sciences of the United States of America, 2014, Mar-25, Volume: 111, Issue:12

    Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Dacarbazine; Glioblastoma; Humans; Mice; Mice, SCID

2014
In vivo chemical exchange saturation transfer imaging allows early detection of a therapeutic response in glioblastoma.
    Proceedings of the National Academy of Sciences of the United States of America, 2014, Mar-25, Volume: 111, Issue:12

    Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Dacarbazine; Glioblastoma; Humans; Mice; Mice, SCID

2014
A novel temozolomide-perillyl alcohol conjugate exhibits superior activity against breast cancer cells in vitro and intracranial triple-negative tumor growth in vivo.
    Molecular cancer therapeutics, 2014, Volume: 13, Issue:5

    Topics: Animals; Brain Neoplasms; Cell Line, Tumor; Cell Survival; Dacarbazine; Disease Models, Animal; DNA

2014
A novel temozolomide-perillyl alcohol conjugate exhibits superior activity against breast cancer cells in vitro and intracranial triple-negative tumor growth in vivo.
    Molecular cancer therapeutics, 2014, Volume: 13, Issue:5

    Topics: Animals; Brain Neoplasms; Cell Line, Tumor; Cell Survival; Dacarbazine; Disease Models, Animal; DNA

2014
A novel temozolomide-perillyl alcohol conjugate exhibits superior activity against breast cancer cells in vitro and intracranial triple-negative tumor growth in vivo.
    Molecular cancer therapeutics, 2014, Volume: 13, Issue:5

    Topics: Animals; Brain Neoplasms; Cell Line, Tumor; Cell Survival; Dacarbazine; Disease Models, Animal; DNA

2014
A BRCA1 deficient-like signature is enriched in breast cancer brain metastases and predicts DNA damage-induced poly (ADP-ribose) polymerase inhibitor sensitivity.
    Breast cancer research : BCR, 2014, Mar-14, Volume: 16, Issue:2

    Topics: Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Brain Neoplasms; BRCA1 Protein; B

2014
A BRCA1 deficient-like signature is enriched in breast cancer brain metastases and predicts DNA damage-induced poly (ADP-ribose) polymerase inhibitor sensitivity.
    Breast cancer research : BCR, 2014, Mar-14, Volume: 16, Issue:2

    Topics: Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Brain Neoplasms; BRCA1 Protein; B

2014
A BRCA1 deficient-like signature is enriched in breast cancer brain metastases and predicts DNA damage-induced poly (ADP-ribose) polymerase inhibitor sensitivity.
    Breast cancer research : BCR, 2014, Mar-14, Volume: 16, Issue:2

    Topics: Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Brain Neoplasms; BRCA1 Protein; B

2014
Profound prevention of experimental brain metastases of breast cancer by temozolomide in an MGMT-dependent manner.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2014, May-15, Volume: 20, Issue:10

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Breast Neoplasms; Cell Line, Tumor; Dac

2014
Profound prevention of experimental brain metastases of breast cancer by temozolomide in an MGMT-dependent manner.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2014, May-15, Volume: 20, Issue:10

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Breast Neoplasms; Cell Line, Tumor; Dac

2014
Profound prevention of experimental brain metastases of breast cancer by temozolomide in an MGMT-dependent manner.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2014, May-15, Volume: 20, Issue:10

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Breast Neoplasms; Cell Line, Tumor; Dac

2014
Impact of systemic treatment on survival after whole brain radiotherapy in patients with brain metastases.
    Medical oncology (Northwood, London, England), 2014, Volume: 31, Issue:4

    Topics: Aged; Antineoplastic Agents; Brain; Brain Neoplasms; Dacarbazine; Female; Humans; Male; Middle Aged;

2014
Impact of systemic treatment on survival after whole brain radiotherapy in patients with brain metastases.
    Medical oncology (Northwood, London, England), 2014, Volume: 31, Issue:4

    Topics: Aged; Antineoplastic Agents; Brain; Brain Neoplasms; Dacarbazine; Female; Humans; Male; Middle Aged;

2014
Impact of systemic treatment on survival after whole brain radiotherapy in patients with brain metastases.
    Medical oncology (Northwood, London, England), 2014, Volume: 31, Issue:4

    Topics: Aged; Antineoplastic Agents; Brain; Brain Neoplasms; Dacarbazine; Female; Humans; Male; Middle Aged;

2014
Relationship between survival and increased radiation dose to subventricular zone in glioblastoma is controversial.
    Journal of neuro-oncology, 2014, Volume: 118, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherap

2014
Relationship between survival and increased radiation dose to subventricular zone in glioblastoma is controversial.
    Journal of neuro-oncology, 2014, Volume: 118, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherap

2014
Relationship between survival and increased radiation dose to subventricular zone in glioblastoma is controversial.
    Journal of neuro-oncology, 2014, Volume: 118, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherap

2014
Antitumor effect of fibrin glue containing temozolomide against malignant glioma.
    Cancer science, 2014, Volume: 105, Issue:5

    Topics: Animals; Antineoplastic Agents, Alkylating; Apoptosis; Autophagy; Brain Neoplasms; Cell Line, Tumor;

2014
Antitumor effect of fibrin glue containing temozolomide against malignant glioma.
    Cancer science, 2014, Volume: 105, Issue:5

    Topics: Animals; Antineoplastic Agents, Alkylating; Apoptosis; Autophagy; Brain Neoplasms; Cell Line, Tumor;

2014
Antitumor effect of fibrin glue containing temozolomide against malignant glioma.
    Cancer science, 2014, Volume: 105, Issue:5

    Topics: Animals; Antineoplastic Agents, Alkylating; Apoptosis; Autophagy; Brain Neoplasms; Cell Line, Tumor;

2014
Temozolomide resistance in glioblastoma cells occurs partly through epidermal growth factor receptor-mediated induction of connexin 43.
    Cell death & disease, 2014, Mar-27, Volume: 5

    Topics: Brain Neoplasms; Cell Line, Tumor; Cell Survival; Coloring Agents; Connexin 43; Dacarbazine; Drug Re

2014
Temozolomide resistance in glioblastoma cells occurs partly through epidermal growth factor receptor-mediated induction of connexin 43.
    Cell death & disease, 2014, Mar-27, Volume: 5

    Topics: Brain Neoplasms; Cell Line, Tumor; Cell Survival; Coloring Agents; Connexin 43; Dacarbazine; Drug Re

2014
Temozolomide resistance in glioblastoma cells occurs partly through epidermal growth factor receptor-mediated induction of connexin 43.
    Cell death & disease, 2014, Mar-27, Volume: 5

    Topics: Brain Neoplasms; Cell Line, Tumor; Cell Survival; Coloring Agents; Connexin 43; Dacarbazine; Drug Re

2014
Fractionated radiotherapy is the main stimulus for the induction of cell death and of Hsp70 release of p53 mutated glioblastoma cell lines.
    Radiation oncology (London, England), 2014, Mar-30, Volume: 9, Issue:1

    Topics: Antineoplastic Agents; Apoptosis; Brain Neoplasms; Cell Cycle; Cell Death; Cell Line, Tumor; Dacarba

2014
Fractionated radiotherapy is the main stimulus for the induction of cell death and of Hsp70 release of p53 mutated glioblastoma cell lines.
    Radiation oncology (London, England), 2014, Mar-30, Volume: 9, Issue:1

    Topics: Antineoplastic Agents; Apoptosis; Brain Neoplasms; Cell Cycle; Cell Death; Cell Line, Tumor; Dacarba

2014
Fractionated radiotherapy is the main stimulus for the induction of cell death and of Hsp70 release of p53 mutated glioblastoma cell lines.
    Radiation oncology (London, England), 2014, Mar-30, Volume: 9, Issue:1

    Topics: Antineoplastic Agents; Apoptosis; Brain Neoplasms; Cell Cycle; Cell Death; Cell Line, Tumor; Dacarba

2014
Liver toxicity during temozolomide chemotherapy caused by Chinese herbs.
    BMC complementary and alternative medicine, 2014, Mar-30, Volume: 14

    Topics: Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Antineoplastic Agents, Alkylating; Bevac

2014
Liver toxicity during temozolomide chemotherapy caused by Chinese herbs.
    BMC complementary and alternative medicine, 2014, Mar-30, Volume: 14

    Topics: Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Antineoplastic Agents, Alkylating; Bevac

2014
Liver toxicity during temozolomide chemotherapy caused by Chinese herbs.
    BMC complementary and alternative medicine, 2014, Mar-30, Volume: 14

    Topics: Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Antineoplastic Agents, Alkylating; Bevac

2014
First use of (18)F-labeled ML-10 PET to assess apoptosis change in a newly diagnosed glioblastoma multiforme patient before and early after therapy.
    Brain and behavior, 2014, Volume: 4, Issue:2

    Topics: Aged; Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Dacarbazine; Glioblastoma; Huma

2014
First use of (18)F-labeled ML-10 PET to assess apoptosis change in a newly diagnosed glioblastoma multiforme patient before and early after therapy.
    Brain and behavior, 2014, Volume: 4, Issue:2

    Topics: Aged; Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Dacarbazine; Glioblastoma; Huma

2014
First use of (18)F-labeled ML-10 PET to assess apoptosis change in a newly diagnosed glioblastoma multiforme patient before and early after therapy.
    Brain and behavior, 2014, Volume: 4, Issue:2

    Topics: Aged; Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Dacarbazine; Glioblastoma; Huma

2014
Durable therapeutic efficacy utilizing combinatorial blockade against IDO, CTLA-4, and PD-L1 in mice with brain tumors.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2014, Oct-15, Volume: 20, Issue:20

    Topics: Animals; Antibodies, Monoclonal; Antineoplastic Agents; B7-H1 Antigen; Brain Neoplasms; Cell Line, T

2014
Durable therapeutic efficacy utilizing combinatorial blockade against IDO, CTLA-4, and PD-L1 in mice with brain tumors.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2014, Oct-15, Volume: 20, Issue:20

    Topics: Animals; Antibodies, Monoclonal; Antineoplastic Agents; B7-H1 Antigen; Brain Neoplasms; Cell Line, T

2014
Durable therapeutic efficacy utilizing combinatorial blockade against IDO, CTLA-4, and PD-L1 in mice with brain tumors.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2014, Oct-15, Volume: 20, Issue:20

    Topics: Animals; Antibodies, Monoclonal; Antineoplastic Agents; B7-H1 Antigen; Brain Neoplasms; Cell Line, T

2014
microRNA expression pattern modulates temozolomide response in GBM tumors with cancer stem cells.
    Cellular and molecular neurobiology, 2014, Volume: 34, Issue:5

    Topics: Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cohort Studies; Dacarbazine; Drug Resistan

2014
microRNA expression pattern modulates temozolomide response in GBM tumors with cancer stem cells.
    Cellular and molecular neurobiology, 2014, Volume: 34, Issue:5

    Topics: Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cohort Studies; Dacarbazine; Drug Resistan

2014
microRNA expression pattern modulates temozolomide response in GBM tumors with cancer stem cells.
    Cellular and molecular neurobiology, 2014, Volume: 34, Issue:5

    Topics: Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cohort Studies; Dacarbazine; Drug Resistan

2014
Combined EGFR and autophagy modulation impairs cell migration and enhances radiosensitivity in human glioblastoma cells.
    Journal of cellular physiology, 2014, Volume: 229, Issue:11

    Topics: Autophagy; Autophagy-Related Protein 7; Brain Neoplasms; Cell Line, Tumor; Cell Movement; Clone Cell

2014
Combined EGFR and autophagy modulation impairs cell migration and enhances radiosensitivity in human glioblastoma cells.
    Journal of cellular physiology, 2014, Volume: 229, Issue:11

    Topics: Autophagy; Autophagy-Related Protein 7; Brain Neoplasms; Cell Line, Tumor; Cell Movement; Clone Cell

2014
Combined EGFR and autophagy modulation impairs cell migration and enhances radiosensitivity in human glioblastoma cells.
    Journal of cellular physiology, 2014, Volume: 229, Issue:11

    Topics: Autophagy; Autophagy-Related Protein 7; Brain Neoplasms; Cell Line, Tumor; Cell Movement; Clone Cell

2014
Combination treatment with theranostic nanoparticles for glioblastoma sensitization to TMZ.
    Molecular imaging and biology, 2014, Volume: 16, Issue:5

    Topics: Animals; Brain Neoplasms; Cell Line, Tumor; Cell Survival; Dacarbazine; Glioblastoma; Humans; Iron;

2014
Combination treatment with theranostic nanoparticles for glioblastoma sensitization to TMZ.
    Molecular imaging and biology, 2014, Volume: 16, Issue:5

    Topics: Animals; Brain Neoplasms; Cell Line, Tumor; Cell Survival; Dacarbazine; Glioblastoma; Humans; Iron;

2014
Combination treatment with theranostic nanoparticles for glioblastoma sensitization to TMZ.
    Molecular imaging and biology, 2014, Volume: 16, Issue:5

    Topics: Animals; Brain Neoplasms; Cell Line, Tumor; Cell Survival; Dacarbazine; Glioblastoma; Humans; Iron;

2014
Hypofractionated chemoradiotherapy with temozolomide as a treatment option for glioblastoma patients with poor prognostic features.
    International journal of clinical oncology, 2015, Volume: 20, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Biopsy; Brain Neoplasms; Chemorad

2015
Hypofractionated chemoradiotherapy with temozolomide as a treatment option for glioblastoma patients with poor prognostic features.
    International journal of clinical oncology, 2015, Volume: 20, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Biopsy; Brain Neoplasms; Chemorad

2015
Hypofractionated chemoradiotherapy with temozolomide as a treatment option for glioblastoma patients with poor prognostic features.
    International journal of clinical oncology, 2015, Volume: 20, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Biopsy; Brain Neoplasms; Chemorad

2015
Glioblastoma: If this is the "Temozolomide Era" Where is the Evidence?
    The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques, 2014, Volume: 41, Issue:3

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Evidence-Based Medicine; Glioblasto

2014
Glioblastoma: If this is the "Temozolomide Era" Where is the Evidence?
    The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques, 2014, Volume: 41, Issue:3

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Evidence-Based Medicine; Glioblasto

2014
Glioblastoma: If this is the "Temozolomide Era" Where is the Evidence?
    The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques, 2014, Volume: 41, Issue:3

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Evidence-Based Medicine; Glioblasto

2014
Glioblastoma treatment in the elderly in the temozolomide therapy era.
    The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques, 2014, Volume: 41, Issue:3

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Coho

2014
Glioblastoma treatment in the elderly in the temozolomide therapy era.
    The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques, 2014, Volume: 41, Issue:3

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Coho

2014
Glioblastoma treatment in the elderly in the temozolomide therapy era.
    The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques, 2014, Volume: 41, Issue:3

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Coho

2014
Temozolomide induces autophagy via ATM‑AMPK‑ULK1 pathways in glioma.
    Molecular medicine reports, 2014, Volume: 10, Issue:1

    Topics: AMP-Activated Protein Kinases; Antineoplastic Agents, Alkylating; Ataxia Telangiectasia Mutated Prot

2014
Temozolomide induces autophagy via ATM‑AMPK‑ULK1 pathways in glioma.
    Molecular medicine reports, 2014, Volume: 10, Issue:1

    Topics: AMP-Activated Protein Kinases; Antineoplastic Agents, Alkylating; Ataxia Telangiectasia Mutated Prot

2014
Temozolomide induces autophagy via ATM‑AMPK‑ULK1 pathways in glioma.
    Molecular medicine reports, 2014, Volume: 10, Issue:1

    Topics: AMP-Activated Protein Kinases; Antineoplastic Agents, Alkylating; Ataxia Telangiectasia Mutated Prot

2014
IDH1 mutation and MGMT methylation status predict survival in patients with anaplastic astrocytoma treated with temozolomide-based chemoradiotherapy.
    Journal of neuro-oncology, 2014, Volume: 118, Issue:2

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Astrocytoma; Biomarkers; Brain Neoplasms; Chemoradio

2014
IDH1 mutation and MGMT methylation status predict survival in patients with anaplastic astrocytoma treated with temozolomide-based chemoradiotherapy.
    Journal of neuro-oncology, 2014, Volume: 118, Issue:2

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Astrocytoma; Biomarkers; Brain Neoplasms; Chemoradio

2014
IDH1 mutation and MGMT methylation status predict survival in patients with anaplastic astrocytoma treated with temozolomide-based chemoradiotherapy.
    Journal of neuro-oncology, 2014, Volume: 118, Issue:2

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Astrocytoma; Biomarkers; Brain Neoplasms; Chemoradio

2014
SDHB mutations are associated with response to temozolomide in patients with metastatic pheochromocytoma or paraganglioma.
    International journal of cancer, 2014, Dec-01, Volume: 135, Issue:11

    Topics: Adrenal Gland Neoplasms; Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Biomarke

2014
SDHB mutations are associated with response to temozolomide in patients with metastatic pheochromocytoma or paraganglioma.
    International journal of cancer, 2014, Dec-01, Volume: 135, Issue:11

    Topics: Adrenal Gland Neoplasms; Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Biomarke

2014
SDHB mutations are associated with response to temozolomide in patients with metastatic pheochromocytoma or paraganglioma.
    International journal of cancer, 2014, Dec-01, Volume: 135, Issue:11

    Topics: Adrenal Gland Neoplasms; Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Biomarke

2014
Differential expression of miR200a-3p and miR21 in grade II-III and grade IV gliomas: evidence that miR200a-3p is regulated by O⁶-methylguanine methyltransferase and promotes temozolomide responsiveness.
    Cancer biology & therapy, 2014, Volume: 15, Issue:7

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor

2014
Differential expression of miR200a-3p and miR21 in grade II-III and grade IV gliomas: evidence that miR200a-3p is regulated by O⁶-methylguanine methyltransferase and promotes temozolomide responsiveness.
    Cancer biology & therapy, 2014, Volume: 15, Issue:7

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor

2014
Differential expression of miR200a-3p and miR21 in grade II-III and grade IV gliomas: evidence that miR200a-3p is regulated by O⁶-methylguanine methyltransferase and promotes temozolomide responsiveness.
    Cancer biology & therapy, 2014, Volume: 15, Issue:7

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor

2014
Experimental study of combined therapy for malignant glioma.
    Bulletin of experimental biology and medicine, 2014, Volume: 156, Issue:4

    Topics: Animals; Animals, Outbred Strains; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms;

2014
Experimental study of combined therapy for malignant glioma.
    Bulletin of experimental biology and medicine, 2014, Volume: 156, Issue:4

    Topics: Animals; Animals, Outbred Strains; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms;

2014
Experimental study of combined therapy for malignant glioma.
    Bulletin of experimental biology and medicine, 2014, Volume: 156, Issue:4

    Topics: Animals; Animals, Outbred Strains; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms;

2014
[Bevacizumab associated with radiotherapy and temozolomide as a first line treatment for high-grade gliomas: one answer but too many questions].
    Revue neurologique, 2014, Volume: 170, Issue:4

    Topics: Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Antineoplastic Agents, Alkylating; Bevac

2014
[Bevacizumab associated with radiotherapy and temozolomide as a first line treatment for high-grade gliomas: one answer but too many questions].
    Revue neurologique, 2014, Volume: 170, Issue:4

    Topics: Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Antineoplastic Agents, Alkylating; Bevac

2014
[Bevacizumab associated with radiotherapy and temozolomide as a first line treatment for high-grade gliomas: one answer but too many questions].
    Revue neurologique, 2014, Volume: 170, Issue:4

    Topics: Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Antineoplastic Agents, Alkylating; Bevac

2014
Combined PDK1 and CHK1 inhibition is required to kill glioblastoma stem-like cells in vitro and in vivo.
    Cell death & disease, 2014, May-08, Volume: 5

    Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Cell Death; Cell Line, Tumor; Checkpoint Kinase 1;

2014
Combined PDK1 and CHK1 inhibition is required to kill glioblastoma stem-like cells in vitro and in vivo.
    Cell death & disease, 2014, May-08, Volume: 5

    Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Cell Death; Cell Line, Tumor; Checkpoint Kinase 1;

2014
Combined PDK1 and CHK1 inhibition is required to kill glioblastoma stem-like cells in vitro and in vivo.
    Cell death & disease, 2014, May-08, Volume: 5

    Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Cell Death; Cell Line, Tumor; Checkpoint Kinase 1;

2014
Bak and Mcl-1 are essential for Temozolomide induced cell death in human glioma.
    Oncotarget, 2014, May-15, Volume: 5, Issue:9

    Topics: Antineoplastic Agents, Alkylating; Apoptosis; bcl-2 Homologous Antagonist-Killer Protein; Blotting,

2014
Bak and Mcl-1 are essential for Temozolomide induced cell death in human glioma.
    Oncotarget, 2014, May-15, Volume: 5, Issue:9

    Topics: Antineoplastic Agents, Alkylating; Apoptosis; bcl-2 Homologous Antagonist-Killer Protein; Blotting,

2014
Bak and Mcl-1 are essential for Temozolomide induced cell death in human glioma.
    Oncotarget, 2014, May-15, Volume: 5, Issue:9

    Topics: Antineoplastic Agents, Alkylating; Apoptosis; bcl-2 Homologous Antagonist-Killer Protein; Blotting,

2014
A nanoparticle carrying the p53 gene targets tumors including cancer stem cells, sensitizes glioblastoma to chemotherapy and improves survival.
    ACS nano, 2014, Jun-24, Volume: 8, Issue:6

    Topics: Animals; Antineoplastic Agents; Apoptosis; Blood-Brain Barrier; Brain Neoplasms; Cell Line, Tumor; D

2014
A nanoparticle carrying the p53 gene targets tumors including cancer stem cells, sensitizes glioblastoma to chemotherapy and improves survival.
    ACS nano, 2014, Jun-24, Volume: 8, Issue:6

    Topics: Animals; Antineoplastic Agents; Apoptosis; Blood-Brain Barrier; Brain Neoplasms; Cell Line, Tumor; D

2014
A nanoparticle carrying the p53 gene targets tumors including cancer stem cells, sensitizes glioblastoma to chemotherapy and improves survival.
    ACS nano, 2014, Jun-24, Volume: 8, Issue:6

    Topics: Animals; Antineoplastic Agents; Apoptosis; Blood-Brain Barrier; Brain Neoplasms; Cell Line, Tumor; D

2014
Kinomic exploration of temozolomide and radiation resistance in Glioblastoma multiforme xenolines.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2014, Volume: 111, Issue:3

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Dacarbazine; Drug Res

2014
Kinomic exploration of temozolomide and radiation resistance in Glioblastoma multiforme xenolines.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2014, Volume: 111, Issue:3

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Dacarbazine; Drug Res

2014
Kinomic exploration of temozolomide and radiation resistance in Glioblastoma multiforme xenolines.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2014, Volume: 111, Issue:3

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Dacarbazine; Drug Res

2014
Multiple cerebral hemorrhagic foci from metastases during temozolomide treatment in a patient with corticotroph pituitary carcinoma.
    The Journal of clinical endocrinology and metabolism, 2014, Volume: 99, Issue:8

    Topics: ACTH-Secreting Pituitary Adenoma; Adenoma; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cereb

2014
Multiple cerebral hemorrhagic foci from metastases during temozolomide treatment in a patient with corticotroph pituitary carcinoma.
    The Journal of clinical endocrinology and metabolism, 2014, Volume: 99, Issue:8

    Topics: ACTH-Secreting Pituitary Adenoma; Adenoma; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cereb

2014
Multiple cerebral hemorrhagic foci from metastases during temozolomide treatment in a patient with corticotroph pituitary carcinoma.
    The Journal of clinical endocrinology and metabolism, 2014, Volume: 99, Issue:8

    Topics: ACTH-Secreting Pituitary Adenoma; Adenoma; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cereb

2014
Elderly patients aged 65-75 years with glioblastoma multiforme may benefit from long course radiation therapy with temozolomide.
    Journal of neuro-oncology, 2014, Volume: 119, Issue:1

    Topics: Age Factors; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined M

2014
Elderly patients aged 65-75 years with glioblastoma multiforme may benefit from long course radiation therapy with temozolomide.
    Journal of neuro-oncology, 2014, Volume: 119, Issue:1

    Topics: Age Factors; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined M

2014
Elderly patients aged 65-75 years with glioblastoma multiforme may benefit from long course radiation therapy with temozolomide.
    Journal of neuro-oncology, 2014, Volume: 119, Issue:1

    Topics: Age Factors; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined M

2014
Discordant in vitro and in vivo chemopotentiating effects of the PARP inhibitor veliparib in temozolomide-sensitive versus -resistant glioblastoma multiforme xenografts.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2014, Jul-15, Volume: 20, Issue:14

    Topics: Animals; Antineoplastic Agents, Alkylating; Benzimidazoles; Brain Neoplasms; Cell Line, Tumor; Dacar

2014
Discordant in vitro and in vivo chemopotentiating effects of the PARP inhibitor veliparib in temozolomide-sensitive versus -resistant glioblastoma multiforme xenografts.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2014, Jul-15, Volume: 20, Issue:14

    Topics: Animals; Antineoplastic Agents, Alkylating; Benzimidazoles; Brain Neoplasms; Cell Line, Tumor; Dacar

2014
Discordant in vitro and in vivo chemopotentiating effects of the PARP inhibitor veliparib in temozolomide-sensitive versus -resistant glioblastoma multiforme xenografts.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2014, Jul-15, Volume: 20, Issue:14

    Topics: Animals; Antineoplastic Agents, Alkylating; Benzimidazoles; Brain Neoplasms; Cell Line, Tumor; Dacar

2014
Synergy of enediyne antibiotic lidamycin and temozolomide in suppressing glioma growth with potentiated apoptosis induction.
    Journal of neuro-oncology, 2014, Volume: 119, Issue:1

    Topics: Aminoglycosides; Animals; Antibiotics, Antineoplastic; Antineoplastic Agents, Alkylating; Apoptosis;

2014
Synergy of enediyne antibiotic lidamycin and temozolomide in suppressing glioma growth with potentiated apoptosis induction.
    Journal of neuro-oncology, 2014, Volume: 119, Issue:1

    Topics: Aminoglycosides; Animals; Antibiotics, Antineoplastic; Antineoplastic Agents, Alkylating; Apoptosis;

2014
Synergy of enediyne antibiotic lidamycin and temozolomide in suppressing glioma growth with potentiated apoptosis induction.
    Journal of neuro-oncology, 2014, Volume: 119, Issue:1

    Topics: Aminoglycosides; Animals; Antibiotics, Antineoplastic; Antineoplastic Agents, Alkylating; Apoptosis;

2014
[Intranasal administration of temozolomide for brain-targeting delivery: therapeutic effect on glioma in rats].
    Nan fang yi ke da xue xue bao = Journal of Southern Medical University, 2014, Volume: 34, Issue:5

    Topics: Administration, Intranasal; Animals; Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms;

2014
[Intranasal administration of temozolomide for brain-targeting delivery: therapeutic effect on glioma in rats].
    Nan fang yi ke da xue xue bao = Journal of Southern Medical University, 2014, Volume: 34, Issue:5

    Topics: Administration, Intranasal; Animals; Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms;

2014
[Intranasal administration of temozolomide for brain-targeting delivery: therapeutic effect on glioma in rats].
    Nan fang yi ke da xue xue bao = Journal of Southern Medical University, 2014, Volume: 34, Issue:5

    Topics: Administration, Intranasal; Animals; Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms;

2014
MiR-124 governs glioma growth and angiogenesis and enhances chemosensitivity by targeting R-Ras and N-Ras.
    Neuro-oncology, 2014, Volume: 16, Issue:10

    Topics: Animals; Apoptosis; Brain; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Dacarbazine; Genes

2014
MiR-124 governs glioma growth and angiogenesis and enhances chemosensitivity by targeting R-Ras and N-Ras.
    Neuro-oncology, 2014, Volume: 16, Issue:10

    Topics: Animals; Apoptosis; Brain; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Dacarbazine; Genes

2014
MiR-124 governs glioma growth and angiogenesis and enhances chemosensitivity by targeting R-Ras and N-Ras.
    Neuro-oncology, 2014, Volume: 16, Issue:10

    Topics: Animals; Apoptosis; Brain; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Dacarbazine; Genes

2014
The effect of field strength on glioblastoma multiforme response in patients treated with the NovoTTF™-100A system.
    World journal of surgical oncology, 2014, May-22, Volume: 12

    Topics: Adult; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Cranial Irradi

2014
The effect of field strength on glioblastoma multiforme response in patients treated with the NovoTTF™-100A system.
    World journal of surgical oncology, 2014, May-22, Volume: 12

    Topics: Adult; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Cranial Irradi

2014
The effect of field strength on glioblastoma multiforme response in patients treated with the NovoTTF™-100A system.
    World journal of surgical oncology, 2014, May-22, Volume: 12

    Topics: Adult; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Cranial Irradi

2014
Whole brain radiation therapy followed by intensity-modulated boosting treatment combined with concomitant temozolomide for brain metastases from non-small-cell lung cancer.
    Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico, 2014, Volume: 16, Issue:11

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Carcinoma, Non-Small-Cell Lung; Com

2014
Whole brain radiation therapy followed by intensity-modulated boosting treatment combined with concomitant temozolomide for brain metastases from non-small-cell lung cancer.
    Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico, 2014, Volume: 16, Issue:11

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Carcinoma, Non-Small-Cell Lung; Com

2014
Whole brain radiation therapy followed by intensity-modulated boosting treatment combined with concomitant temozolomide for brain metastases from non-small-cell lung cancer.
    Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico, 2014, Volume: 16, Issue:11

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Carcinoma, Non-Small-Cell Lung; Com

2014
Quercetin sensitizes human glioblastoma cells to temozolomide in vitro via inhibition of Hsp27.
    Acta pharmacologica Sinica, 2014, Volume: 35, Issue:6

    Topics: Antineoplastic Agents, Alkylating; Brain; Brain Neoplasms; Caspase 3; Cell Line, Tumor; Dacarbazine;

2014
Quercetin sensitizes human glioblastoma cells to temozolomide in vitro via inhibition of Hsp27.
    Acta pharmacologica Sinica, 2014, Volume: 35, Issue:6

    Topics: Antineoplastic Agents, Alkylating; Brain; Brain Neoplasms; Caspase 3; Cell Line, Tumor; Dacarbazine;

2014
Quercetin sensitizes human glioblastoma cells to temozolomide in vitro via inhibition of Hsp27.
    Acta pharmacologica Sinica, 2014, Volume: 35, Issue:6

    Topics: Antineoplastic Agents, Alkylating; Brain; Brain Neoplasms; Caspase 3; Cell Line, Tumor; Dacarbazine;

2014
Longitudinal quality of life data: a comparison of continuous and ordinal approaches.
    Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation, 2014, Volume: 23, Issue:10

    Topics: Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Appetite; Brain Neoplas

2014
Longitudinal quality of life data: a comparison of continuous and ordinal approaches.
    Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation, 2014, Volume: 23, Issue:10

    Topics: Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Appetite; Brain Neoplas

2014
Longitudinal quality of life data: a comparison of continuous and ordinal approaches.
    Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation, 2014, Volume: 23, Issue:10

    Topics: Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Appetite; Brain Neoplas

2014
Patterns of failure for glioblastoma multiforme following limited-margin radiation and concurrent temozolomide.
    Radiation oncology (London, England), 2014, Jun-06, Volume: 9

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Dacarbazine; Fem

2014
Patterns of failure for glioblastoma multiforme following limited-margin radiation and concurrent temozolomide.
    Radiation oncology (London, England), 2014, Jun-06, Volume: 9

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Dacarbazine; Fem

2014
Patterns of failure for glioblastoma multiforme following limited-margin radiation and concurrent temozolomide.
    Radiation oncology (London, England), 2014, Jun-06, Volume: 9

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Dacarbazine; Fem

2014
Molecular targeting of TRF2 suppresses the growth and tumorigenesis of glioblastoma stem cells.
    Glia, 2014, Volume: 62, Issue:10

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Carcinogenesis; Cell Differentiation; C

2014
Molecular targeting of TRF2 suppresses the growth and tumorigenesis of glioblastoma stem cells.
    Glia, 2014, Volume: 62, Issue:10

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Carcinogenesis; Cell Differentiation; C

2014
Molecular targeting of TRF2 suppresses the growth and tumorigenesis of glioblastoma stem cells.
    Glia, 2014, Volume: 62, Issue:10

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Carcinogenesis; Cell Differentiation; C

2014
Bevacizumab as secondline treatment of glioblastoma -  worth the effort?
    Klinicka onkologie : casopis Ceske a Slovenske onkologicke spolecnosti, 2014, Volume: 27, Issue:3

    Topics: Adult; Aged; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Bevacizumab; Brain Neoplasm

2014
Bevacizumab as secondline treatment of glioblastoma -  worth the effort?
    Klinicka onkologie : casopis Ceske a Slovenske onkologicke spolecnosti, 2014, Volume: 27, Issue:3

    Topics: Adult; Aged; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Bevacizumab; Brain Neoplasm

2014
Bevacizumab as secondline treatment of glioblastoma -  worth the effort?
    Klinicka onkologie : casopis Ceske a Slovenske onkologicke spolecnosti, 2014, Volume: 27, Issue:3

    Topics: Adult; Aged; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Bevacizumab; Brain Neoplasm

2014
Hyperoxia resensitizes chemoresistant glioblastoma cells to temozolomide through unfolded protein response.
    Anticancer research, 2014, Volume: 34, Issue:6

    Topics: Antineoplastic Agents, Alkylating; Apoptosis; Blotting, Western; Brain Neoplasms; Cell Proliferation

2014
Hyperoxia resensitizes chemoresistant glioblastoma cells to temozolomide through unfolded protein response.
    Anticancer research, 2014, Volume: 34, Issue:6

    Topics: Antineoplastic Agents, Alkylating; Apoptosis; Blotting, Western; Brain Neoplasms; Cell Proliferation

2014
Hyperoxia resensitizes chemoresistant glioblastoma cells to temozolomide through unfolded protein response.
    Anticancer research, 2014, Volume: 34, Issue:6

    Topics: Antineoplastic Agents, Alkylating; Apoptosis; Blotting, Western; Brain Neoplasms; Cell Proliferation

2014
TERT promoter mutations lead to high transcriptional activity under hypoxia and temozolomide treatment and predict poor prognosis in gliomas.
    PloS one, 2014, Volume: 9, Issue:6

    Topics: Antineoplastic Agents, Alkylating; Biomarkers, Tumor; Brain Neoplasms; Dacarbazine; Female; Follow-U

2014
TERT promoter mutations lead to high transcriptional activity under hypoxia and temozolomide treatment and predict poor prognosis in gliomas.
    PloS one, 2014, Volume: 9, Issue:6

    Topics: Antineoplastic Agents, Alkylating; Biomarkers, Tumor; Brain Neoplasms; Dacarbazine; Female; Follow-U

2014
TERT promoter mutations lead to high transcriptional activity under hypoxia and temozolomide treatment and predict poor prognosis in gliomas.
    PloS one, 2014, Volume: 9, Issue:6

    Topics: Antineoplastic Agents, Alkylating; Biomarkers, Tumor; Brain Neoplasms; Dacarbazine; Female; Follow-U

2014
MiR-143 acts as a tumor suppressor by targeting N-RAS and enhances temozolomide-induced apoptosis in glioma.
    Oncotarget, 2014, Jul-30, Volume: 5, Issue:14

    Topics: Animals; Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cell Proli

2014
MiR-143 acts as a tumor suppressor by targeting N-RAS and enhances temozolomide-induced apoptosis in glioma.
    Oncotarget, 2014, Jul-30, Volume: 5, Issue:14

    Topics: Animals; Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cell Proli

2014
MiR-143 acts as a tumor suppressor by targeting N-RAS and enhances temozolomide-induced apoptosis in glioma.
    Oncotarget, 2014, Jul-30, Volume: 5, Issue:14

    Topics: Animals; Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cell Proli

2014
A complex mechanism for HDGF-mediated cell growth, migration, invasion, and TMZ chemosensitivity in glioma.
    Journal of neuro-oncology, 2014, Volume: 119, Issue:2

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cadherins; C

2014
A complex mechanism for HDGF-mediated cell growth, migration, invasion, and TMZ chemosensitivity in glioma.
    Journal of neuro-oncology, 2014, Volume: 119, Issue:2

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cadherins; C

2014
A complex mechanism for HDGF-mediated cell growth, migration, invasion, and TMZ chemosensitivity in glioma.
    Journal of neuro-oncology, 2014, Volume: 119, Issue:2

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cadherins; C

2014
3-Dimensional magnetic resonance spectroscopic imaging at 3 Tesla for early response assessment of glioblastoma patients during external beam radiation therapy.
    International journal of radiation oncology, biology, physics, 2014, Sep-01, Volume: 90, Issue:1

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Aspartic Acid; Biomarkers, Tumor; Brain Neoplasms; C

2014
3-Dimensional magnetic resonance spectroscopic imaging at 3 Tesla for early response assessment of glioblastoma patients during external beam radiation therapy.
    International journal of radiation oncology, biology, physics, 2014, Sep-01, Volume: 90, Issue:1

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Aspartic Acid; Biomarkers, Tumor; Brain Neoplasms; C

2014
3-Dimensional magnetic resonance spectroscopic imaging at 3 Tesla for early response assessment of glioblastoma patients during external beam radiation therapy.
    International journal of radiation oncology, biology, physics, 2014, Sep-01, Volume: 90, Issue:1

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Aspartic Acid; Biomarkers, Tumor; Brain Neoplasms; C

2014
The impact of concurrent temozolomide with adjuvant radiation and IDH mutation status among patients with anaplastic astrocytoma.
    Journal of neuro-oncology, 2014, Volume: 120, Issue:1

    Topics: Adult; Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neoplasms; Chemoradiotherapy, Adjuvant;

2014
The impact of concurrent temozolomide with adjuvant radiation and IDH mutation status among patients with anaplastic astrocytoma.
    Journal of neuro-oncology, 2014, Volume: 120, Issue:1

    Topics: Adult; Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neoplasms; Chemoradiotherapy, Adjuvant;

2014
The impact of concurrent temozolomide with adjuvant radiation and IDH mutation status among patients with anaplastic astrocytoma.
    Journal of neuro-oncology, 2014, Volume: 120, Issue:1

    Topics: Adult; Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neoplasms; Chemoradiotherapy, Adjuvant;

2014
Significant anti-tumor effect of bevacizumab in treatment of pineal gland glioblastoma multiforme.
    Targeted oncology, 2014, Volume: 9, Issue:4

    Topics: Aged; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Bevacizumab

2014
Significant anti-tumor effect of bevacizumab in treatment of pineal gland glioblastoma multiforme.
    Targeted oncology, 2014, Volume: 9, Issue:4

    Topics: Aged; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Bevacizumab

2014
Significant anti-tumor effect of bevacizumab in treatment of pineal gland glioblastoma multiforme.
    Targeted oncology, 2014, Volume: 9, Issue:4

    Topics: Aged; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Bevacizumab

2014
miR-128 and miR-149 enhance the chemosensitivity of temozolomide by Rap1B-mediated cytoskeletal remodeling in glioblastoma.
    Oncology reports, 2014, Volume: 32, Issue:3

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Cell Movement; Cell Proliferat

2014
miR-128 and miR-149 enhance the chemosensitivity of temozolomide by Rap1B-mediated cytoskeletal remodeling in glioblastoma.
    Oncology reports, 2014, Volume: 32, Issue:3

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Cell Movement; Cell Proliferat

2014
miR-128 and miR-149 enhance the chemosensitivity of temozolomide by Rap1B-mediated cytoskeletal remodeling in glioblastoma.
    Oncology reports, 2014, Volume: 32, Issue:3

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Cell Movement; Cell Proliferat

2014
Analyzing temozolomide medication errors: potentially fatal.
    Journal of neuro-oncology, 2014, Volume: 120, Issue:1

    Topics: Adverse Drug Reaction Reporting Systems; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarba

2014
Analyzing temozolomide medication errors: potentially fatal.
    Journal of neuro-oncology, 2014, Volume: 120, Issue:1

    Topics: Adverse Drug Reaction Reporting Systems; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarba

2014
Analyzing temozolomide medication errors: potentially fatal.
    Journal of neuro-oncology, 2014, Volume: 120, Issue:1

    Topics: Adverse Drug Reaction Reporting Systems; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarba

2014
Treatment-related Acute Myeloid Leukaemia After Temozolomide for Glioblastoma Multiforme.
    Annals of the Academy of Medicine, Singapore, 2014, Volume: 43, Issue:6

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Female; Glioblastoma; Humans; Leuke

2014
Treatment-related Acute Myeloid Leukaemia After Temozolomide for Glioblastoma Multiforme.
    Annals of the Academy of Medicine, Singapore, 2014, Volume: 43, Issue:6

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Female; Glioblastoma; Humans; Leuke

2014
Treatment-related Acute Myeloid Leukaemia After Temozolomide for Glioblastoma Multiforme.
    Annals of the Academy of Medicine, Singapore, 2014, Volume: 43, Issue:6

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Female; Glioblastoma; Humans; Leuke

2014
Survival outcomes of giant cell glioblastoma: institutional experience in the management of 20 patients.
    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2014, Volume: 21, Issue:12

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Disease Pr

2014
Survival outcomes of giant cell glioblastoma: institutional experience in the management of 20 patients.
    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2014, Volume: 21, Issue:12

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Disease Pr

2014
Survival outcomes of giant cell glioblastoma: institutional experience in the management of 20 patients.
    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2014, Volume: 21, Issue:12

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Disease Pr

2014
Effect of neoadjuvant temozolomide upon volume reduction and resection of diffuse low-grade glioma.
    Journal of neuro-oncology, 2014, Volume: 120, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemother

2014
Effect of neoadjuvant temozolomide upon volume reduction and resection of diffuse low-grade glioma.
    Journal of neuro-oncology, 2014, Volume: 120, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemother

2014
Effect of neoadjuvant temozolomide upon volume reduction and resection of diffuse low-grade glioma.
    Journal of neuro-oncology, 2014, Volume: 120, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemother

2014
Toxicity profile of temozolomide in the treatment of 300 malignant glioma patients in Korea.
    Journal of Korean medical science, 2014, Volume: 29, Issue:7

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anorexia; Antineoplastic Agents, Alkylating; Brain Neopl

2014
Toxicity profile of temozolomide in the treatment of 300 malignant glioma patients in Korea.
    Journal of Korean medical science, 2014, Volume: 29, Issue:7

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anorexia; Antineoplastic Agents, Alkylating; Brain Neopl

2014
Toxicity profile of temozolomide in the treatment of 300 malignant glioma patients in Korea.
    Journal of Korean medical science, 2014, Volume: 29, Issue:7

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anorexia; Antineoplastic Agents, Alkylating; Brain Neopl

2014
Aplysin enhances temozolomide sensitivity in glioma cells by increasing miR-181 level.
    Cancer chemotherapy and pharmacology, 2014, Volume: 74, Issue:3

    Topics: Animals; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Apoptosi

2014
Aplysin enhances temozolomide sensitivity in glioma cells by increasing miR-181 level.
    Cancer chemotherapy and pharmacology, 2014, Volume: 74, Issue:3

    Topics: Animals; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Apoptosi

2014
Aplysin enhances temozolomide sensitivity in glioma cells by increasing miR-181 level.
    Cancer chemotherapy and pharmacology, 2014, Volume: 74, Issue:3

    Topics: Animals; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Apoptosi

2014
Local delivery of cancer-cell glycolytic inhibitors in high-grade glioma.
    Neuro-oncology, 2015, Volume: 17, Issue:1

    Topics: Absorbable Implants; Animals; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Brain Neopla

2015
Local delivery of cancer-cell glycolytic inhibitors in high-grade glioma.
    Neuro-oncology, 2015, Volume: 17, Issue:1

    Topics: Absorbable Implants; Animals; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Brain Neopla

2015
Local delivery of cancer-cell glycolytic inhibitors in high-grade glioma.
    Neuro-oncology, 2015, Volume: 17, Issue:1

    Topics: Absorbable Implants; Animals; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Brain Neopla

2015
Seizure reduction in a low-grade glioma: more than a beneficial side effect of temozolomide.
    Journal of neurology, neurosurgery, and psychiatry, 2015, Volume: 86, Issue:4

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease-

2015
Seizure reduction in a low-grade glioma: more than a beneficial side effect of temozolomide.
    Journal of neurology, neurosurgery, and psychiatry, 2015, Volume: 86, Issue:4

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease-

2015
Seizure reduction in a low-grade glioma: more than a beneficial side effect of temozolomide.
    Journal of neurology, neurosurgery, and psychiatry, 2015, Volume: 86, Issue:4

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease-

2015
FANCD2 re-expression is associated with glioma grade and chemical inhibition of the Fanconi Anaemia pathway sensitises gliomas to chemotherapeutic agents.
    Oncotarget, 2014, Aug-15, Volume: 5, Issue:15

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Carmustine; Cell Line, Tumor; Curcumin; Dacarbaz

2014
FANCD2 re-expression is associated with glioma grade and chemical inhibition of the Fanconi Anaemia pathway sensitises gliomas to chemotherapeutic agents.
    Oncotarget, 2014, Aug-15, Volume: 5, Issue:15

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Carmustine; Cell Line, Tumor; Curcumin; Dacarbaz

2014
FANCD2 re-expression is associated with glioma grade and chemical inhibition of the Fanconi Anaemia pathway sensitises gliomas to chemotherapeutic agents.
    Oncotarget, 2014, Aug-15, Volume: 5, Issue:15

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Carmustine; Cell Line, Tumor; Curcumin; Dacarbaz

2014
Survival in granular cell astrocytomas.
    Journal of neurological surgery. Part A, Central European neurosurgery, 2015, Volume: 76, Issue:1

    Topics: Adult; Age Factors; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Astrocytoma; Brain N

2015
Survival in granular cell astrocytomas.
    Journal of neurological surgery. Part A, Central European neurosurgery, 2015, Volume: 76, Issue:1

    Topics: Adult; Age Factors; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Astrocytoma; Brain N

2015
Survival in granular cell astrocytomas.
    Journal of neurological surgery. Part A, Central European neurosurgery, 2015, Volume: 76, Issue:1

    Topics: Adult; Age Factors; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Astrocytoma; Brain N

2015
Radio-chemotherapy with temozolomide in elderly patients with glioblastoma. A mono-institutional experience.
    Anticancer research, 2014, Volume: 34, Issue:8

    Topics: Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Daca

2014
Radio-chemotherapy with temozolomide in elderly patients with glioblastoma. A mono-institutional experience.
    Anticancer research, 2014, Volume: 34, Issue:8

    Topics: Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Daca

2014
Radio-chemotherapy with temozolomide in elderly patients with glioblastoma. A mono-institutional experience.
    Anticancer research, 2014, Volume: 34, Issue:8

    Topics: Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Daca

2014
Novel MSH6 mutations in treatment-naïve glioblastoma and anaplastic oligodendroglioma contribute to temozolomide resistance independently of MGMT promoter methylation.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2014, Sep-15, Volume: 20, Issue:18

    Topics: Adult; Aged; Aged, 80 and over; Animals; Antineoplastic Agents, Alkylating; Blotting, Western; Brain

2014
Novel MSH6 mutations in treatment-naïve glioblastoma and anaplastic oligodendroglioma contribute to temozolomide resistance independently of MGMT promoter methylation.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2014, Sep-15, Volume: 20, Issue:18

    Topics: Adult; Aged; Aged, 80 and over; Animals; Antineoplastic Agents, Alkylating; Blotting, Western; Brain

2014
Novel MSH6 mutations in treatment-naïve glioblastoma and anaplastic oligodendroglioma contribute to temozolomide resistance independently of MGMT promoter methylation.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2014, Sep-15, Volume: 20, Issue:18

    Topics: Adult; Aged; Aged, 80 and over; Animals; Antineoplastic Agents, Alkylating; Blotting, Western; Brain

2014
Hypoxia-induced miR-497 decreases glioma cell sensitivity to TMZ by inhibiting apoptosis.
    FEBS letters, 2014, Sep-17, Volume: 588, Issue:18

    Topics: Antineoplastic Agents, Alkylating; Apoptosis; Apoptosis Regulatory Proteins; Base Sequence; Binding

2014
Hypoxia-induced miR-497 decreases glioma cell sensitivity to TMZ by inhibiting apoptosis.
    FEBS letters, 2014, Sep-17, Volume: 588, Issue:18

    Topics: Antineoplastic Agents, Alkylating; Apoptosis; Apoptosis Regulatory Proteins; Base Sequence; Binding

2014
Hypoxia-induced miR-497 decreases glioma cell sensitivity to TMZ by inhibiting apoptosis.
    FEBS letters, 2014, Sep-17, Volume: 588, Issue:18

    Topics: Antineoplastic Agents, Alkylating; Apoptosis; Apoptosis Regulatory Proteins; Base Sequence; Binding

2014
Exogenous IGFBP-2 promotes proliferation, invasion, and chemoresistance to temozolomide in glioma cells via the integrin β1-ERK pathway.
    British journal of cancer, 2014, Sep-23, Volume: 111, Issue:7

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Dacarbazin

2014
Exogenous IGFBP-2 promotes proliferation, invasion, and chemoresistance to temozolomide in glioma cells via the integrin β1-ERK pathway.
    British journal of cancer, 2014, Sep-23, Volume: 111, Issue:7

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Dacarbazin

2014
Exogenous IGFBP-2 promotes proliferation, invasion, and chemoresistance to temozolomide in glioma cells via the integrin β1-ERK pathway.
    British journal of cancer, 2014, Sep-23, Volume: 111, Issue:7

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Dacarbazin

2014
Is the absolute value of O(6)-methylguanine-DNA methyltransferase gene messenger RNA a prognostic factor, and does it predict the results of treatment of glioblastoma with temozolomide?
    Journal of neurosurgery, 2014, Volume: 121, Issue:4

    Topics: Adult; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Disease-Free Survival; Femal

2014
Is the absolute value of O(6)-methylguanine-DNA methyltransferase gene messenger RNA a prognostic factor, and does it predict the results of treatment of glioblastoma with temozolomide?
    Journal of neurosurgery, 2014, Volume: 121, Issue:4

    Topics: Adult; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Disease-Free Survival; Femal

2014
Is the absolute value of O(6)-methylguanine-DNA methyltransferase gene messenger RNA a prognostic factor, and does it predict the results of treatment of glioblastoma with temozolomide?
    Journal of neurosurgery, 2014, Volume: 121, Issue:4

    Topics: Adult; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Disease-Free Survival; Femal

2014
Treatment of poorly differentiated glioma using a combination of monoclonal antibodies to extracellular connexin-43 fragment, temozolomide, and radiotherapy.
    Bulletin of experimental biology and medicine, 2014, Volume: 157, Issue:4

    Topics: Animals; Antibodies, Monoclonal; Antineoplastic Agents, Alkylating; Blood-Brain Barrier; Brain Neopl

2014
Treatment of poorly differentiated glioma using a combination of monoclonal antibodies to extracellular connexin-43 fragment, temozolomide, and radiotherapy.
    Bulletin of experimental biology and medicine, 2014, Volume: 157, Issue:4

    Topics: Animals; Antibodies, Monoclonal; Antineoplastic Agents, Alkylating; Blood-Brain Barrier; Brain Neopl

2014
Treatment of poorly differentiated glioma using a combination of monoclonal antibodies to extracellular connexin-43 fragment, temozolomide, and radiotherapy.
    Bulletin of experimental biology and medicine, 2014, Volume: 157, Issue:4

    Topics: Animals; Antibodies, Monoclonal; Antineoplastic Agents, Alkylating; Blood-Brain Barrier; Brain Neopl

2014
RIST: a potent new combination therapy for glioblastoma.
    International journal of cancer, 2015, Feb-15, Volume: 136, Issue:4

    Topics: Adolescent; Animals; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Camptothecin;

2015
RIST: a potent new combination therapy for glioblastoma.
    International journal of cancer, 2015, Feb-15, Volume: 136, Issue:4

    Topics: Adolescent; Animals; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Camptothecin;

2015
RIST: a potent new combination therapy for glioblastoma.
    International journal of cancer, 2015, Feb-15, Volume: 136, Issue:4

    Topics: Adolescent; Animals; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Camptothecin;

2015
RNA-seq of 272 gliomas revealed a novel, recurrent PTPRZ1-MET fusion transcript in secondary glioblastomas.
    Genome research, 2014, Volume: 24, Issue:11

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Blotting, Western; Brain Neoplasms; Cell

2014
RNA-seq of 272 gliomas revealed a novel, recurrent PTPRZ1-MET fusion transcript in secondary glioblastomas.
    Genome research, 2014, Volume: 24, Issue:11

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Blotting, Western; Brain Neoplasms; Cell

2014
RNA-seq of 272 gliomas revealed a novel, recurrent PTPRZ1-MET fusion transcript in secondary glioblastomas.
    Genome research, 2014, Volume: 24, Issue:11

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Blotting, Western; Brain Neoplasms; Cell

2014
Clinicopathological and molecular features of malignant optic pathway glioma in an adult.
    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2015, Volume: 22, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2015
Clinicopathological and molecular features of malignant optic pathway glioma in an adult.
    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2015, Volume: 22, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2015
Clinicopathological and molecular features of malignant optic pathway glioma in an adult.
    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2015, Volume: 22, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2015
Low-dose rate stereotactic iodine-125 brachytherapy for the treatment of inoperable primary and recurrent glioblastoma: single-center experience with 201 cases.
    Journal of neuro-oncology, 2014, Volume: 120, Issue:3

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brachytherapy; Brain

2014
Low-dose rate stereotactic iodine-125 brachytherapy for the treatment of inoperable primary and recurrent glioblastoma: single-center experience with 201 cases.
    Journal of neuro-oncology, 2014, Volume: 120, Issue:3

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brachytherapy; Brain

2014
Low-dose rate stereotactic iodine-125 brachytherapy for the treatment of inoperable primary and recurrent glioblastoma: single-center experience with 201 cases.
    Journal of neuro-oncology, 2014, Volume: 120, Issue:3

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brachytherapy; Brain

2014
Cilengitide in glioblastoma: when did it fail?
    The Lancet. Oncology, 2014, Volume: 15, Issue:10

    Topics: Brain Neoplasms; Dacarbazine; DNA Modification Methylases; DNA Repair Enzymes; Female; Glioblastoma;

2014
Cilengitide in glioblastoma: when did it fail?
    The Lancet. Oncology, 2014, Volume: 15, Issue:10

    Topics: Brain Neoplasms; Dacarbazine; DNA Modification Methylases; DNA Repair Enzymes; Female; Glioblastoma;

2014
Cilengitide in glioblastoma: when did it fail?
    The Lancet. Oncology, 2014, Volume: 15, Issue:10

    Topics: Brain Neoplasms; Dacarbazine; DNA Modification Methylases; DNA Repair Enzymes; Female; Glioblastoma;

2014
Primary brain tumors: introduction.
    Seminars in oncology, 2014, Volume: 41, Issue:4

    Topics: Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Astrocytoma; Beva

2014
Primary brain tumors: introduction.
    Seminars in oncology, 2014, Volume: 41, Issue:4

    Topics: Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Astrocytoma; Beva

2014
Primary brain tumors: introduction.
    Seminars in oncology, 2014, Volume: 41, Issue:4

    Topics: Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Astrocytoma; Beva

2014
Temozolomide in low-grade gliomas: living longer and better.
    Journal of neurology, neurosurgery, and psychiatry, 2015, Volume: 86, Issue:4

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Female; Glioma; Humans; Male; Seizu

2015
Temozolomide in low-grade gliomas: living longer and better.
    Journal of neurology, neurosurgery, and psychiatry, 2015, Volume: 86, Issue:4

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Female; Glioma; Humans; Male; Seizu

2015
Temozolomide in low-grade gliomas: living longer and better.
    Journal of neurology, neurosurgery, and psychiatry, 2015, Volume: 86, Issue:4

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Female; Glioma; Humans; Male; Seizu

2015
Nocardia abscesses mimicking tumor progression in gliomatosis cerebri responding to temozolomide.
    Journal of neuro-oncology, 2015, Volume: 121, Issue:1

    Topics: Aged; Antineoplastic Agents, Alkylating; Brain; Brain Abscess; Brain Neoplasms; Dacarbazine; Humans;

2015
Nocardia abscesses mimicking tumor progression in gliomatosis cerebri responding to temozolomide.
    Journal of neuro-oncology, 2015, Volume: 121, Issue:1

    Topics: Aged; Antineoplastic Agents, Alkylating; Brain; Brain Abscess; Brain Neoplasms; Dacarbazine; Humans;

2015
Nocardia abscesses mimicking tumor progression in gliomatosis cerebri responding to temozolomide.
    Journal of neuro-oncology, 2015, Volume: 121, Issue:1

    Topics: Aged; Antineoplastic Agents, Alkylating; Brain; Brain Abscess; Brain Neoplasms; Dacarbazine; Humans;

2015
The butterfly effect on glioblastoma: is volumetric extent of resection more effective than biopsy for these tumors?
    Journal of neuro-oncology, 2014, Volume: 120, Issue:3

    Topics: Antineoplastic Agents, Alkylating; Biopsy, Needle; Brain; Brain Neoplasms; Dacarbazine; Female; Glio

2014
The butterfly effect on glioblastoma: is volumetric extent of resection more effective than biopsy for these tumors?
    Journal of neuro-oncology, 2014, Volume: 120, Issue:3

    Topics: Antineoplastic Agents, Alkylating; Biopsy, Needle; Brain; Brain Neoplasms; Dacarbazine; Female; Glio

2014
The butterfly effect on glioblastoma: is volumetric extent of resection more effective than biopsy for these tumors?
    Journal of neuro-oncology, 2014, Volume: 120, Issue:3

    Topics: Antineoplastic Agents, Alkylating; Biopsy, Needle; Brain; Brain Neoplasms; Dacarbazine; Female; Glio

2014
Molecular imaging coupled to pattern recognition distinguishes response to temozolomide in preclinical glioblastoma.
    NMR in biomedicine, 2014, Volume: 27, Issue:11

    Topics: Animals; Antineoplastic Agents, Alkylating; Apoptosis; Brain; Brain Neoplasms; Cell Line, Tumor; Dac

2014
Molecular imaging coupled to pattern recognition distinguishes response to temozolomide in preclinical glioblastoma.
    NMR in biomedicine, 2014, Volume: 27, Issue:11

    Topics: Animals; Antineoplastic Agents, Alkylating; Apoptosis; Brain; Brain Neoplasms; Cell Line, Tumor; Dac

2014
Molecular imaging coupled to pattern recognition distinguishes response to temozolomide in preclinical glioblastoma.
    NMR in biomedicine, 2014, Volume: 27, Issue:11

    Topics: Animals; Antineoplastic Agents, Alkylating; Apoptosis; Brain; Brain Neoplasms; Cell Line, Tumor; Dac

2014
VAMP8 facilitates cellular proliferation and temozolomide resistance in human glioma cells.
    Neuro-oncology, 2015, Volume: 17, Issue:3

    Topics: Antineoplastic Agents, Alkylating; Autophagy; Biomarkers, Tumor; Brain Neoplasms; Cell Cycle; Cell P

2015
VAMP8 facilitates cellular proliferation and temozolomide resistance in human glioma cells.
    Neuro-oncology, 2015, Volume: 17, Issue:3

    Topics: Antineoplastic Agents, Alkylating; Autophagy; Biomarkers, Tumor; Brain Neoplasms; Cell Cycle; Cell P

2015
VAMP8 facilitates cellular proliferation and temozolomide resistance in human glioma cells.
    Neuro-oncology, 2015, Volume: 17, Issue:3

    Topics: Antineoplastic Agents, Alkylating; Autophagy; Biomarkers, Tumor; Brain Neoplasms; Cell Cycle; Cell P

2015
SapC-DOPS-induced lysosomal cell death synergizes with TMZ in glioblastoma.
    Oncotarget, 2014, Oct-30, Volume: 5, Issue:20

    Topics: Animals; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Brain Ne

2014
SapC-DOPS-induced lysosomal cell death synergizes with TMZ in glioblastoma.
    Oncotarget, 2014, Oct-30, Volume: 5, Issue:20

    Topics: Animals; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Brain Ne

2014
SapC-DOPS-induced lysosomal cell death synergizes with TMZ in glioblastoma.
    Oncotarget, 2014, Oct-30, Volume: 5, Issue:20

    Topics: Animals; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Brain Ne

2014
CUSP9* treatment protocol for recurrent glioblastoma: aprepitant, artesunate, auranofin, captopril, celecoxib, disulfiram, itraconazole, ritonavir, sertraline augmenting continuous low dose temozolomide.
    Oncotarget, 2014, Sep-30, Volume: 5, Issue:18

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Aprepitant; Artemisinins; Artesunate; Auran

2014
CUSP9* treatment protocol for recurrent glioblastoma: aprepitant, artesunate, auranofin, captopril, celecoxib, disulfiram, itraconazole, ritonavir, sertraline augmenting continuous low dose temozolomide.
    Oncotarget, 2014, Sep-30, Volume: 5, Issue:18

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Aprepitant; Artemisinins; Artesunate; Auran

2014
CUSP9* treatment protocol for recurrent glioblastoma: aprepitant, artesunate, auranofin, captopril, celecoxib, disulfiram, itraconazole, ritonavir, sertraline augmenting continuous low dose temozolomide.
    Oncotarget, 2014, Sep-30, Volume: 5, Issue:18

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Aprepitant; Artemisinins; Artesunate; Auran

2014
Ficus carica latex prevents invasion through induction of let-7d expression in GBM cell lines.
    Cellular and molecular neurobiology, 2015, Volume: 35, Issue:2

    Topics: Antineoplastic Agents; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Cell Surviv

2015
Ficus carica latex prevents invasion through induction of let-7d expression in GBM cell lines.
    Cellular and molecular neurobiology, 2015, Volume: 35, Issue:2

    Topics: Antineoplastic Agents; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Cell Surviv

2015
Ficus carica latex prevents invasion through induction of let-7d expression in GBM cell lines.
    Cellular and molecular neurobiology, 2015, Volume: 35, Issue:2

    Topics: Antineoplastic Agents; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Cell Surviv

2015
Glioblastoma recurrence patterns after radiation therapy with regard to the subventricular zone.
    International journal of radiation oncology, biology, physics, 2014, Nov-15, Volume: 90, Issue:4

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chil

2014
Glioblastoma recurrence patterns after radiation therapy with regard to the subventricular zone.
    International journal of radiation oncology, biology, physics, 2014, Nov-15, Volume: 90, Issue:4

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chil

2014
Glioblastoma recurrence patterns after radiation therapy with regard to the subventricular zone.
    International journal of radiation oncology, biology, physics, 2014, Nov-15, Volume: 90, Issue:4

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chil

2014
Annexin A5 promotes invasion and chemoresistance to temozolomide in glioblastoma multiforme cells.
    Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine, 2014, Volume: 35, Issue:12

    Topics: Annexin A5; Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cadherins; Cell Line, Tum

2014
Annexin A5 promotes invasion and chemoresistance to temozolomide in glioblastoma multiforme cells.
    Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine, 2014, Volume: 35, Issue:12

    Topics: Annexin A5; Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cadherins; Cell Line, Tum

2014
Annexin A5 promotes invasion and chemoresistance to temozolomide in glioblastoma multiforme cells.
    Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine, 2014, Volume: 35, Issue:12

    Topics: Annexin A5; Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cadherins; Cell Line, Tum

2014
Asiatic acid induces endoplasmic reticulum stress and apoptotic death in glioblastoma multiforme cells both in vitro and in vivo.
    Molecular carcinogenesis, 2015, Volume: 54, Issue:11

    Topics: Animals; Apoptosis; Apoptosis Regulatory Proteins; Brain Neoplasms; Cell Line, Tumor; Dacarbazine; E

2015
Asiatic acid induces endoplasmic reticulum stress and apoptotic death in glioblastoma multiforme cells both in vitro and in vivo.
    Molecular carcinogenesis, 2015, Volume: 54, Issue:11

    Topics: Animals; Apoptosis; Apoptosis Regulatory Proteins; Brain Neoplasms; Cell Line, Tumor; Dacarbazine; E

2015
Asiatic acid induces endoplasmic reticulum stress and apoptotic death in glioblastoma multiforme cells both in vitro and in vivo.
    Molecular carcinogenesis, 2015, Volume: 54, Issue:11

    Topics: Animals; Apoptosis; Apoptosis Regulatory Proteins; Brain Neoplasms; Cell Line, Tumor; Dacarbazine; E

2015
A sphingosine kinase inhibitor combined with temozolomide induces glioblastoma cell death through accumulation of dihydrosphingosine and dihydroceramide, endoplasmic reticulum stress and autophagy.
    Cell death & disease, 2014, Sep-25, Volume: 5

    Topics: Antineoplastic Agents; Apoptosis; Autophagy; Brain Neoplasms; Cell Death; Cell Line, Tumor; Ceramide

2014
A sphingosine kinase inhibitor combined with temozolomide induces glioblastoma cell death through accumulation of dihydrosphingosine and dihydroceramide, endoplasmic reticulum stress and autophagy.
    Cell death & disease, 2014, Sep-25, Volume: 5

    Topics: Antineoplastic Agents; Apoptosis; Autophagy; Brain Neoplasms; Cell Death; Cell Line, Tumor; Ceramide

2014
A sphingosine kinase inhibitor combined with temozolomide induces glioblastoma cell death through accumulation of dihydrosphingosine and dihydroceramide, endoplasmic reticulum stress and autophagy.
    Cell death & disease, 2014, Sep-25, Volume: 5

    Topics: Antineoplastic Agents; Apoptosis; Autophagy; Brain Neoplasms; Cell Death; Cell Line, Tumor; Ceramide

2014
Inhibition of Na+/K+-ATPase induces hybrid cell death and enhanced sensitivity to chemotherapy in human glioblastoma cells.
    BMC cancer, 2014, Sep-26, Volume: 14

    Topics: Antineoplastic Agents; Apoptosis; Brain Neoplasms; Calcium; Cell Line, Tumor; Dacarbazine; Drug Resi

2014
Inhibition of Na+/K+-ATPase induces hybrid cell death and enhanced sensitivity to chemotherapy in human glioblastoma cells.
    BMC cancer, 2014, Sep-26, Volume: 14

    Topics: Antineoplastic Agents; Apoptosis; Brain Neoplasms; Calcium; Cell Line, Tumor; Dacarbazine; Drug Resi

2014
Inhibition of Na+/K+-ATPase induces hybrid cell death and enhanced sensitivity to chemotherapy in human glioblastoma cells.
    BMC cancer, 2014, Sep-26, Volume: 14

    Topics: Antineoplastic Agents; Apoptosis; Brain Neoplasms; Calcium; Cell Line, Tumor; Dacarbazine; Drug Resi

2014
Radiation therapy dose escalation for glioblastoma multiforme in the era of temozolomide.
    International journal of radiation oncology, biology, physics, 2014, Nov-15, Volume: 90, Issue:4

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbaz

2014
Radiation therapy dose escalation for glioblastoma multiforme in the era of temozolomide.
    International journal of radiation oncology, biology, physics, 2014, Nov-15, Volume: 90, Issue:4

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbaz

2014
Radiation therapy dose escalation for glioblastoma multiforme in the era of temozolomide.
    International journal of radiation oncology, biology, physics, 2014, Nov-15, Volume: 90, Issue:4

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbaz

2014
Concomitant treatment with temozolomide enhances apoptotic cell death in glioma cells induced by photodynamic therapy with talaporfin sodium.
    Photodiagnosis and photodynamic therapy, 2014, Volume: 11, Issue:4

    Topics: Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Dacarbazine; Drug T

2014
Concomitant treatment with temozolomide enhances apoptotic cell death in glioma cells induced by photodynamic therapy with talaporfin sodium.
    Photodiagnosis and photodynamic therapy, 2014, Volume: 11, Issue:4

    Topics: Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Dacarbazine; Drug T

2014
Concomitant treatment with temozolomide enhances apoptotic cell death in glioma cells induced by photodynamic therapy with talaporfin sodium.
    Photodiagnosis and photodynamic therapy, 2014, Volume: 11, Issue:4

    Topics: Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Dacarbazine; Drug T

2014
A co-culture model with brain tumor-specific bioluminescence demonstrates astrocyte-induced drug resistance in glioblastoma.
    Journal of translational medicine, 2014, Oct-04, Volume: 12

    Topics: Astrocytes; Brain Neoplasms; Cell Compartmentation; Cell Count; Cell Line, Tumor; Cell Survival; Coc

2014
A co-culture model with brain tumor-specific bioluminescence demonstrates astrocyte-induced drug resistance in glioblastoma.
    Journal of translational medicine, 2014, Oct-04, Volume: 12

    Topics: Astrocytes; Brain Neoplasms; Cell Compartmentation; Cell Count; Cell Line, Tumor; Cell Survival; Coc

2014
A co-culture model with brain tumor-specific bioluminescence demonstrates astrocyte-induced drug resistance in glioblastoma.
    Journal of translational medicine, 2014, Oct-04, Volume: 12

    Topics: Astrocytes; Brain Neoplasms; Cell Compartmentation; Cell Count; Cell Line, Tumor; Cell Survival; Coc

2014
ADC texture--an imaging biomarker for high-grade glioma?
    Medical physics, 2014, Volume: 41, Issue:10

    Topics: Adult; Age Factors; Aged; Antineoplastic Agents, Alkylating; Brain; Brain Neoplasms; Chemoradiothera

2014
ADC texture--an imaging biomarker for high-grade glioma?
    Medical physics, 2014, Volume: 41, Issue:10

    Topics: Adult; Age Factors; Aged; Antineoplastic Agents, Alkylating; Brain; Brain Neoplasms; Chemoradiothera

2014
ADC texture--an imaging biomarker for high-grade glioma?
    Medical physics, 2014, Volume: 41, Issue:10

    Topics: Adult; Age Factors; Aged; Antineoplastic Agents, Alkylating; Brain; Brain Neoplasms; Chemoradiothera

2014
Retrospective analysis of safety and feasibility of a 3 days on/11 days off temozolomide dosing regimen in recurrent adult malignant gliomas.
    CNS oncology, 2014, Volume: 3, Issue:4

    Topics: Administration, Oral; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine;

2014
Retrospective analysis of safety and feasibility of a 3 days on/11 days off temozolomide dosing regimen in recurrent adult malignant gliomas.
    CNS oncology, 2014, Volume: 3, Issue:4

    Topics: Administration, Oral; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine;

2014
Retrospective analysis of safety and feasibility of a 3 days on/11 days off temozolomide dosing regimen in recurrent adult malignant gliomas.
    CNS oncology, 2014, Volume: 3, Issue:4

    Topics: Administration, Oral; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine;

2014
Incidence of Pneumocystis jirovecii pneumonia after temozolomide for CNS malignancies without prophylaxis.
    CNS oncology, 2014, Volume: 3, Issue:4

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chil

2014
Incidence of Pneumocystis jirovecii pneumonia after temozolomide for CNS malignancies without prophylaxis.
    CNS oncology, 2014, Volume: 3, Issue:4

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chil

2014
Incidence of Pneumocystis jirovecii pneumonia after temozolomide for CNS malignancies without prophylaxis.
    CNS oncology, 2014, Volume: 3, Issue:4

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chil

2014
Improvement in treatment results of glioblastoma over the last three decades and beneficial factors.
    British journal of neurosurgery, 2015, Volume: 29, Issue:2

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant; Dacarbazine; Female; Gli

2015
Improvement in treatment results of glioblastoma over the last three decades and beneficial factors.
    British journal of neurosurgery, 2015, Volume: 29, Issue:2

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant; Dacarbazine; Female; Gli

2015
Improvement in treatment results of glioblastoma over the last three decades and beneficial factors.
    British journal of neurosurgery, 2015, Volume: 29, Issue:2

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant; Dacarbazine; Female; Gli

2015
Dual mTORC1/2 blockade inhibits glioblastoma brain tumor initiating cells in vitro and in vivo and synergizes with temozolomide to increase orthotopic xenograft survival.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2014, Nov-15, Volume: 20, Issue:22

    Topics: Animals; Antineoplastic Agents; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Ce

2014
Dual mTORC1/2 blockade inhibits glioblastoma brain tumor initiating cells in vitro and in vivo and synergizes with temozolomide to increase orthotopic xenograft survival.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2014, Nov-15, Volume: 20, Issue:22

    Topics: Animals; Antineoplastic Agents; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Ce

2014
Dual mTORC1/2 blockade inhibits glioblastoma brain tumor initiating cells in vitro and in vivo and synergizes with temozolomide to increase orthotopic xenograft survival.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2014, Nov-15, Volume: 20, Issue:22

    Topics: Animals; Antineoplastic Agents; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Ce

2014
Glioblastoma treated with concurrent radiation therapy and temozolomide chemotherapy: differentiation of true progression from pseudoprogression with quantitative dynamic contrast-enhanced MR imaging.
    Radiology, 2015, Volume: 274, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modalit

2015
Glioblastoma treated with concurrent radiation therapy and temozolomide chemotherapy: differentiation of true progression from pseudoprogression with quantitative dynamic contrast-enhanced MR imaging.
    Radiology, 2015, Volume: 274, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modalit

2015
Glioblastoma treated with concurrent radiation therapy and temozolomide chemotherapy: differentiation of true progression from pseudoprogression with quantitative dynamic contrast-enhanced MR imaging.
    Radiology, 2015, Volume: 274, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modalit

2015
Downregulation of BRCA1-BRCA2-containing complex subunit 3 sensitizes glioma cells to temozolomide.
    Oncotarget, 2014, Nov-15, Volume: 5, Issue:21

    Topics: Animals; Antineoplastic Agents, Alkylating; Apoptosis; Blotting, Western; Brain Neoplasms; Cell Prol

2014
Downregulation of BRCA1-BRCA2-containing complex subunit 3 sensitizes glioma cells to temozolomide.
    Oncotarget, 2014, Nov-15, Volume: 5, Issue:21

    Topics: Animals; Antineoplastic Agents, Alkylating; Apoptosis; Blotting, Western; Brain Neoplasms; Cell Prol

2014
Downregulation of BRCA1-BRCA2-containing complex subunit 3 sensitizes glioma cells to temozolomide.
    Oncotarget, 2014, Nov-15, Volume: 5, Issue:21

    Topics: Animals; Antineoplastic Agents, Alkylating; Apoptosis; Blotting, Western; Brain Neoplasms; Cell Prol

2014
Intracranial microcapsule chemotherapy delivery for the localized treatment of rodent metastatic breast adenocarcinoma in the brain.
    Proceedings of the National Academy of Sciences of the United States of America, 2014, Nov-11, Volume: 111, Issue:45

    Topics: Adenocarcinoma; Animals; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Capsules;

2014
Intracranial microcapsule chemotherapy delivery for the localized treatment of rodent metastatic breast adenocarcinoma in the brain.
    Proceedings of the National Academy of Sciences of the United States of America, 2014, Nov-11, Volume: 111, Issue:45

    Topics: Adenocarcinoma; Animals; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Capsules;

2014
Intracranial microcapsule chemotherapy delivery for the localized treatment of rodent metastatic breast adenocarcinoma in the brain.
    Proceedings of the National Academy of Sciences of the United States of America, 2014, Nov-11, Volume: 111, Issue:45

    Topics: Adenocarcinoma; Animals; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Capsules;

2014
Estrogen receptor β agonist enhances temozolomide sensitivity of glioma cells by inhibiting PI3K/AKT/mTOR pathway.
    Molecular medicine reports, 2015, Volume: 11, Issue:2

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Cell Survival; Dacarbazine; Es

2015
Estrogen receptor β agonist enhances temozolomide sensitivity of glioma cells by inhibiting PI3K/AKT/mTOR pathway.
    Molecular medicine reports, 2015, Volume: 11, Issue:2

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Cell Survival; Dacarbazine; Es

2015
Estrogen receptor β agonist enhances temozolomide sensitivity of glioma cells by inhibiting PI3K/AKT/mTOR pathway.
    Molecular medicine reports, 2015, Volume: 11, Issue:2

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Cell Survival; Dacarbazine; Es

2015
Comparison of ADC metrics and their association with outcome for patients with newly diagnosed glioblastoma being treated with radiation therapy, temozolomide, erlotinib and bevacizumab.
    Journal of neuro-oncology, 2015, Volume: 121, Issue:2

    Topics: Adult; Aged; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Bevacizumab; Brain; Brain Neo

2015
Comparison of ADC metrics and their association with outcome for patients with newly diagnosed glioblastoma being treated with radiation therapy, temozolomide, erlotinib and bevacizumab.
    Journal of neuro-oncology, 2015, Volume: 121, Issue:2

    Topics: Adult; Aged; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Bevacizumab; Brain; Brain Neo

2015
Comparison of ADC metrics and their association with outcome for patients with newly diagnosed glioblastoma being treated with radiation therapy, temozolomide, erlotinib and bevacizumab.
    Journal of neuro-oncology, 2015, Volume: 121, Issue:2

    Topics: Adult; Aged; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Bevacizumab; Brain; Brain Neo

2015
Evaluation of novel imidazotetrazine analogues designed to overcome temozolomide resistance and glioblastoma regrowth.
    Molecular cancer therapeutics, 2015, Volume: 14, Issue:1

    Topics: Aniline Compounds; Animals; Antineoplastic Agents, Alkylating; Ataxia Telangiectasia Mutated Protein

2015
Evaluation of novel imidazotetrazine analogues designed to overcome temozolomide resistance and glioblastoma regrowth.
    Molecular cancer therapeutics, 2015, Volume: 14, Issue:1

    Topics: Aniline Compounds; Animals; Antineoplastic Agents, Alkylating; Ataxia Telangiectasia Mutated Protein

2015
Evaluation of novel imidazotetrazine analogues designed to overcome temozolomide resistance and glioblastoma regrowth.
    Molecular cancer therapeutics, 2015, Volume: 14, Issue:1

    Topics: Aniline Compounds; Animals; Antineoplastic Agents, Alkylating; Ataxia Telangiectasia Mutated Protein

2015
Glutathione depletion sensitizes cisplatin- and temozolomide-resistant glioma cells in vitro and in vivo.
    Cell death & disease, 2014, Oct-30, Volume: 5

    Topics: Animals; Apoptosis; Brain Neoplasms; Buthionine Sulfoximine; Cell Line, Tumor; Cell Survival; Cispla

2014
Glutathione depletion sensitizes cisplatin- and temozolomide-resistant glioma cells in vitro and in vivo.
    Cell death & disease, 2014, Oct-30, Volume: 5

    Topics: Animals; Apoptosis; Brain Neoplasms; Buthionine Sulfoximine; Cell Line, Tumor; Cell Survival; Cispla

2014
Glutathione depletion sensitizes cisplatin- and temozolomide-resistant glioma cells in vitro and in vivo.
    Cell death & disease, 2014, Oct-30, Volume: 5

    Topics: Animals; Apoptosis; Brain Neoplasms; Buthionine Sulfoximine; Cell Line, Tumor; Cell Survival; Cispla

2014
Livin contributes to tumor hypoxia-induced resistance to cytotoxic therapies in glioblastoma multiforme.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2015, Jan-15, Volume: 21, Issue:2

    Topics: Adaptor Proteins, Signal Transducing; Animals; Antineoplastic Agents, Alkylating; Apoptosis; Brain N

2015
Livin contributes to tumor hypoxia-induced resistance to cytotoxic therapies in glioblastoma multiforme.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2015, Jan-15, Volume: 21, Issue:2

    Topics: Adaptor Proteins, Signal Transducing; Animals; Antineoplastic Agents, Alkylating; Apoptosis; Brain N

2015
Livin contributes to tumor hypoxia-induced resistance to cytotoxic therapies in glioblastoma multiforme.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2015, Jan-15, Volume: 21, Issue:2

    Topics: Adaptor Proteins, Signal Transducing; Animals; Antineoplastic Agents, Alkylating; Apoptosis; Brain N

2015
Combination of the mTOR inhibitor RAD001 with temozolomide and radiation effectively inhibits the growth of glioblastoma cells in culture.
    Oncology reports, 2015, Volume: 33, Issue:1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Brain Neoplasms; Cell Proliferation; Cell

2015
Combination of the mTOR inhibitor RAD001 with temozolomide and radiation effectively inhibits the growth of glioblastoma cells in culture.
    Oncology reports, 2015, Volume: 33, Issue:1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Brain Neoplasms; Cell Proliferation; Cell

2015
Combination of the mTOR inhibitor RAD001 with temozolomide and radiation effectively inhibits the growth of glioblastoma cells in culture.
    Oncology reports, 2015, Volume: 33, Issue:1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Brain Neoplasms; Cell Proliferation; Cell

2015
Suppressor of fused (Sufu) represses Gli1 transcription and nuclear accumulation, inhibits glioma cell proliferation, invasion and vasculogenic mimicry, improving glioma chemo-sensitivity and prognosis.
    Oncotarget, 2014, Nov-30, Volume: 5, Issue:22

    Topics: Adult; Animals; Brain Neoplasms; Cell Line, Tumor; Cell Nucleus; Cell Proliferation; Dacarbazine; Di

2014
Suppressor of fused (Sufu) represses Gli1 transcription and nuclear accumulation, inhibits glioma cell proliferation, invasion and vasculogenic mimicry, improving glioma chemo-sensitivity and prognosis.
    Oncotarget, 2014, Nov-30, Volume: 5, Issue:22

    Topics: Adult; Animals; Brain Neoplasms; Cell Line, Tumor; Cell Nucleus; Cell Proliferation; Dacarbazine; Di

2014
Suppressor of fused (Sufu) represses Gli1 transcription and nuclear accumulation, inhibits glioma cell proliferation, invasion and vasculogenic mimicry, improving glioma chemo-sensitivity and prognosis.
    Oncotarget, 2014, Nov-30, Volume: 5, Issue:22

    Topics: Adult; Animals; Brain Neoplasms; Cell Line, Tumor; Cell Nucleus; Cell Proliferation; Dacarbazine; Di

2014
Inhibition of EZH2 reverses chemotherapeutic drug TMZ chemosensitivity in glioblastoma.
    International journal of clinical and experimental pathology, 2014, Volume: 7, Issue:10

    Topics: Antineoplastic Agents, Alkylating; Apoptosis; ATP Binding Cassette Transporter, Subfamily G, Member

2014
Inhibition of EZH2 reverses chemotherapeutic drug TMZ chemosensitivity in glioblastoma.
    International journal of clinical and experimental pathology, 2014, Volume: 7, Issue:10

    Topics: Antineoplastic Agents, Alkylating; Apoptosis; ATP Binding Cassette Transporter, Subfamily G, Member

2014
Inhibition of EZH2 reverses chemotherapeutic drug TMZ chemosensitivity in glioblastoma.
    International journal of clinical and experimental pathology, 2014, Volume: 7, Issue:10

    Topics: Antineoplastic Agents, Alkylating; Apoptosis; ATP Binding Cassette Transporter, Subfamily G, Member

2014
Mutational analysis reveals the origin and therapy-driven evolution of recurrent glioma.
    Neurosurgery, 2014, Volume: 75, Issue:6

    Topics: Antineoplastic Agents; Brain Neoplasms; Cell Transformation, Neoplastic; Dacarbazine; Glioma; Humans

2014
Mutational analysis reveals the origin and therapy-driven evolution of recurrent glioma.
    Neurosurgery, 2014, Volume: 75, Issue:6

    Topics: Antineoplastic Agents; Brain Neoplasms; Cell Transformation, Neoplastic; Dacarbazine; Glioma; Humans

2014
Mutational analysis reveals the origin and therapy-driven evolution of recurrent glioma.
    Neurosurgery, 2014, Volume: 75, Issue:6

    Topics: Antineoplastic Agents; Brain Neoplasms; Cell Transformation, Neoplastic; Dacarbazine; Glioma; Humans

2014
Prognosis prediction of measurable enhancing lesion after completion of standard concomitant chemoradiotherapy and adjuvant temozolomide in glioblastoma patients: application of dynamic susceptibility contrast perfusion and diffusion-weighted imaging.
    PloS one, 2014, Volume: 9, Issue:11

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chem

2014
Prognosis prediction of measurable enhancing lesion after completion of standard concomitant chemoradiotherapy and adjuvant temozolomide in glioblastoma patients: application of dynamic susceptibility contrast perfusion and diffusion-weighted imaging.
    PloS one, 2014, Volume: 9, Issue:11

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chem

2014
Prognosis prediction of measurable enhancing lesion after completion of standard concomitant chemoradiotherapy and adjuvant temozolomide in glioblastoma patients: application of dynamic susceptibility contrast perfusion and diffusion-weighted imaging.
    PloS one, 2014, Volume: 9, Issue:11

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chem

2014
Modulation of A1 and A2B adenosine receptor activity: a new strategy to sensitise glioblastoma stem cells to chemotherapy.
    Cell death & disease, 2014, Nov-27, Volume: 5

    Topics: Adenosine A1 Receptor Agonists; Adenosine A2 Receptor Agonists; Apoptosis; Brain Neoplasms; Cell Dif

2014
Modulation of A1 and A2B adenosine receptor activity: a new strategy to sensitise glioblastoma stem cells to chemotherapy.
    Cell death & disease, 2014, Nov-27, Volume: 5

    Topics: Adenosine A1 Receptor Agonists; Adenosine A2 Receptor Agonists; Apoptosis; Brain Neoplasms; Cell Dif

2014
Modulation of A1 and A2B adenosine receptor activity: a new strategy to sensitise glioblastoma stem cells to chemotherapy.
    Cell death & disease, 2014, Nov-27, Volume: 5

    Topics: Adenosine A1 Receptor Agonists; Adenosine A2 Receptor Agonists; Apoptosis; Brain Neoplasms; Cell Dif

2014
Medical treatment of orthotopic glioblastoma with transferrin-conjugated nanoparticles encapsulating zoledronic acid.
    Oncotarget, 2014, Nov-15, Volume: 5, Issue:21

    Topics: Animals; Apoptosis; Blood-Brain Barrier; Brain Neoplasms; Cell Growth Processes; Cell Line, Tumor; D

2014
Medical treatment of orthotopic glioblastoma with transferrin-conjugated nanoparticles encapsulating zoledronic acid.
    Oncotarget, 2014, Nov-15, Volume: 5, Issue:21

    Topics: Animals; Apoptosis; Blood-Brain Barrier; Brain Neoplasms; Cell Growth Processes; Cell Line, Tumor; D

2014
Medical treatment of orthotopic glioblastoma with transferrin-conjugated nanoparticles encapsulating zoledronic acid.
    Oncotarget, 2014, Nov-15, Volume: 5, Issue:21

    Topics: Animals; Apoptosis; Blood-Brain Barrier; Brain Neoplasms; Cell Growth Processes; Cell Line, Tumor; D

2014
Vanishing bile duct syndrome in the context of concurrent temozolomide for glioblastoma.
    BMJ case reports, 2014, Nov-28, Volume: 2014

    Topics: Antineoplastic Agents, Alkylating; Biopsy, Needle; Brain Neoplasms; Chemical and Drug Induced Liver

2014
Vanishing bile duct syndrome in the context of concurrent temozolomide for glioblastoma.
    BMJ case reports, 2014, Nov-28, Volume: 2014

    Topics: Antineoplastic Agents, Alkylating; Biopsy, Needle; Brain Neoplasms; Chemical and Drug Induced Liver

2014
Vanishing bile duct syndrome in the context of concurrent temozolomide for glioblastoma.
    BMJ case reports, 2014, Nov-28, Volume: 2014

    Topics: Antineoplastic Agents, Alkylating; Biopsy, Needle; Brain Neoplasms; Chemical and Drug Induced Liver

2014
Knockdown of CDC2 expression inhibits proliferation, enhances apoptosis, and increases chemosensitivity to temozolomide in glioblastoma cells.
    Medical oncology (Northwood, London, England), 2015, Volume: 32, Issue:1

    Topics: Adult; Aged; Antineoplastic Agents; Apoptosis; Blotting, Western; Brain Neoplasms; CDC2 Protein Kina

2015
Knockdown of CDC2 expression inhibits proliferation, enhances apoptosis, and increases chemosensitivity to temozolomide in glioblastoma cells.
    Medical oncology (Northwood, London, England), 2015, Volume: 32, Issue:1

    Topics: Adult; Aged; Antineoplastic Agents; Apoptosis; Blotting, Western; Brain Neoplasms; CDC2 Protein Kina

2015
Knockdown of CDC2 expression inhibits proliferation, enhances apoptosis, and increases chemosensitivity to temozolomide in glioblastoma cells.
    Medical oncology (Northwood, London, England), 2015, Volume: 32, Issue:1

    Topics: Adult; Aged; Antineoplastic Agents; Apoptosis; Blotting, Western; Brain Neoplasms; CDC2 Protein Kina

2015
Long-term therapy with temozolomide is a feasible option for newly diagnosed glioblastoma: a single-institution experience with as many as 101 temozolomide cycles.
    Neurosurgical focus, 2014, Volume: 37, Issue:6

    Topics: Adrenal Cortex Hormones; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms

2014
Long-term therapy with temozolomide is a feasible option for newly diagnosed glioblastoma: a single-institution experience with as many as 101 temozolomide cycles.
    Neurosurgical focus, 2014, Volume: 37, Issue:6

    Topics: Adrenal Cortex Hormones; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms

2014
Long-term therapy with temozolomide is a feasible option for newly diagnosed glioblastoma: a single-institution experience with as many as 101 temozolomide cycles.
    Neurosurgical focus, 2014, Volume: 37, Issue:6

    Topics: Adrenal Cortex Hormones; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms

2014
Standard (60 Gy) or short-course (40 Gy) irradiation plus concomitant and adjuvant temozolomide for elderly patients with glioblastoma: a propensity-matched analysis.
    International journal of radiation oncology, biology, physics, 2015, Jan-01, Volume: 91, Issue:1

    Topics: Adrenal Cortex Hormones; Age Factors; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Br

2015
Standard (60 Gy) or short-course (40 Gy) irradiation plus concomitant and adjuvant temozolomide for elderly patients with glioblastoma: a propensity-matched analysis.
    International journal of radiation oncology, biology, physics, 2015, Jan-01, Volume: 91, Issue:1

    Topics: Adrenal Cortex Hormones; Age Factors; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Br

2015
Standard (60 Gy) or short-course (40 Gy) irradiation plus concomitant and adjuvant temozolomide for elderly patients with glioblastoma: a propensity-matched analysis.
    International journal of radiation oncology, biology, physics, 2015, Jan-01, Volume: 91, Issue:1

    Topics: Adrenal Cortex Hormones; Age Factors; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Br

2015
Combination of photodynamic therapy and temozolomide on glioma in a rat C6 glioma model.
    Photodiagnosis and photodynamic therapy, 2014, Volume: 11, Issue:4

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Dacarbazine; Drug The

2014
Combination of photodynamic therapy and temozolomide on glioma in a rat C6 glioma model.
    Photodiagnosis and photodynamic therapy, 2014, Volume: 11, Issue:4

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Dacarbazine; Drug The

2014
Combination of photodynamic therapy and temozolomide on glioma in a rat C6 glioma model.
    Photodiagnosis and photodynamic therapy, 2014, Volume: 11, Issue:4

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Dacarbazine; Drug The

2014
Prediction of clinical outcome in glioblastoma using a biologically relevant nine-microRNA signature.
    Molecular oncology, 2015, Volume: 9, Issue:3

    Topics: Aged; Brain Neoplasms; Cell Line, Tumor; Dacarbazine; Databases, Genetic; Female; Gene Expression Pr

2015
Prediction of clinical outcome in glioblastoma using a biologically relevant nine-microRNA signature.
    Molecular oncology, 2015, Volume: 9, Issue:3

    Topics: Aged; Brain Neoplasms; Cell Line, Tumor; Dacarbazine; Databases, Genetic; Female; Gene Expression Pr

2015
Prediction of clinical outcome in glioblastoma using a biologically relevant nine-microRNA signature.
    Molecular oncology, 2015, Volume: 9, Issue:3

    Topics: Aged; Brain Neoplasms; Cell Line, Tumor; Dacarbazine; Databases, Genetic; Female; Gene Expression Pr

2015
Olanzapine inhibits proliferation, migration and anchorage-independent growth in human glioblastoma cell lines and enhances temozolomide's antiproliferative effect.
    Journal of neuro-oncology, 2015, Volume: 122, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Antipsychotic Agents; Apoptosis; Benzodiazepines; Blotting, Weste

2015
Olanzapine inhibits proliferation, migration and anchorage-independent growth in human glioblastoma cell lines and enhances temozolomide's antiproliferative effect.
    Journal of neuro-oncology, 2015, Volume: 122, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Antipsychotic Agents; Apoptosis; Benzodiazepines; Blotting, Weste

2015
Olanzapine inhibits proliferation, migration and anchorage-independent growth in human glioblastoma cell lines and enhances temozolomide's antiproliferative effect.
    Journal of neuro-oncology, 2015, Volume: 122, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Antipsychotic Agents; Apoptosis; Benzodiazepines; Blotting, Weste

2015
Glioblastoma multiforme and hepatitis B: do the right thing(s).
    European review for medical and pharmacological sciences, 2014, Volume: 18, Issue:23

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Glioblastoma; Hepatitis B; Hepatiti

2014
Glioblastoma multiforme and hepatitis B: do the right thing(s).
    European review for medical and pharmacological sciences, 2014, Volume: 18, Issue:23

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Glioblastoma; Hepatitis B; Hepatiti

2014
Glioblastoma multiforme and hepatitis B: do the right thing(s).
    European review for medical and pharmacological sciences, 2014, Volume: 18, Issue:23

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Glioblastoma; Hepatitis B; Hepatiti

2014
miR-155 Regulates Glioma Cells Invasion and Chemosensitivity by p38 Isforms In Vitro.
    Journal of cellular biochemistry, 2015, Volume: 116, Issue:7

    Topics: Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cell Movement; Cell Proliferation; Dacarbazine; Gene K

2015
miR-155 Regulates Glioma Cells Invasion and Chemosensitivity by p38 Isforms In Vitro.
    Journal of cellular biochemistry, 2015, Volume: 116, Issue:7

    Topics: Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cell Movement; Cell Proliferation; Dacarbazine; Gene K

2015
miR-155 Regulates Glioma Cells Invasion and Chemosensitivity by p38 Isforms In Vitro.
    Journal of cellular biochemistry, 2015, Volume: 116, Issue:7

    Topics: Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cell Movement; Cell Proliferation; Dacarbazine; Gene K

2015
Chemotherapeutic effect of tamoxifen on temozolomide-resistant gliomas.
    Anti-cancer drugs, 2015, Volume: 26, Issue:3

    Topics: Animals; Antineoplastic Agents, Hormonal; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Dacarbazine;

2015
Chemotherapeutic effect of tamoxifen on temozolomide-resistant gliomas.
    Anti-cancer drugs, 2015, Volume: 26, Issue:3

    Topics: Animals; Antineoplastic Agents, Hormonal; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Dacarbazine;

2015
Chemotherapeutic effect of tamoxifen on temozolomide-resistant gliomas.
    Anti-cancer drugs, 2015, Volume: 26, Issue:3

    Topics: Animals; Antineoplastic Agents, Hormonal; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Dacarbazine;

2015
Autophagy inhibition improves the efficacy of curcumin/temozolomide combination therapy in glioblastomas.
    Cancer letters, 2015, Mar-28, Volume: 358, Issue:2

    Topics: Animals; Apoptosis; Autophagy; Brain Neoplasms; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Survi

2015
Autophagy inhibition improves the efficacy of curcumin/temozolomide combination therapy in glioblastomas.
    Cancer letters, 2015, Mar-28, Volume: 358, Issue:2

    Topics: Animals; Apoptosis; Autophagy; Brain Neoplasms; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Survi

2015
Autophagy inhibition improves the efficacy of curcumin/temozolomide combination therapy in glioblastomas.
    Cancer letters, 2015, Mar-28, Volume: 358, Issue:2

    Topics: Animals; Apoptosis; Autophagy; Brain Neoplasms; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Survi

2015
Silencing erythropoietin receptor on glioma cells reinforces efficacy of temozolomide and X-rays through senescence and mitotic catastrophe.
    Oncotarget, 2015, Feb-10, Volume: 6, Issue:4

    Topics: Animals; Antineoplastic Agents, Alkylating; Blotting, Western; Brain Neoplasms; Cell Cycle Checkpoin

2015
Silencing erythropoietin receptor on glioma cells reinforces efficacy of temozolomide and X-rays through senescence and mitotic catastrophe.
    Oncotarget, 2015, Feb-10, Volume: 6, Issue:4

    Topics: Animals; Antineoplastic Agents, Alkylating; Blotting, Western; Brain Neoplasms; Cell Cycle Checkpoin

2015
Silencing erythropoietin receptor on glioma cells reinforces efficacy of temozolomide and X-rays through senescence and mitotic catastrophe.
    Oncotarget, 2015, Feb-10, Volume: 6, Issue:4

    Topics: Animals; Antineoplastic Agents, Alkylating; Blotting, Western; Brain Neoplasms; Cell Cycle Checkpoin

2015
Tamoxifen in combination with temozolomide induce a synergistic inhibition of PKC-pan in GBM cell lines.
    Biochimica et biophysica acta, 2015, Volume: 1850, Issue:4

    Topics: Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Dacarbazine; Drug Synergism; Gliob

2015
Tamoxifen in combination with temozolomide induce a synergistic inhibition of PKC-pan in GBM cell lines.
    Biochimica et biophysica acta, 2015, Volume: 1850, Issue:4

    Topics: Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Dacarbazine; Drug Synergism; Gliob

2015
Tamoxifen in combination with temozolomide induce a synergistic inhibition of PKC-pan in GBM cell lines.
    Biochimica et biophysica acta, 2015, Volume: 1850, Issue:4

    Topics: Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Dacarbazine; Drug Synergism; Gliob

2015
Single cell-derived clonal analysis of human glioblastoma links functional and genomic heterogeneity.
    Proceedings of the National Academy of Sciences of the United States of America, 2015, Jan-20, Volume: 112, Issue:3

    Topics: Antineoplastic Agents; Brain Neoplasms; Cell Line, Tumor; Dacarbazine; Drug Resistance, Neoplasm; Gl

2015
Single cell-derived clonal analysis of human glioblastoma links functional and genomic heterogeneity.
    Proceedings of the National Academy of Sciences of the United States of America, 2015, Jan-20, Volume: 112, Issue:3

    Topics: Antineoplastic Agents; Brain Neoplasms; Cell Line, Tumor; Dacarbazine; Drug Resistance, Neoplasm; Gl

2015
Single cell-derived clonal analysis of human glioblastoma links functional and genomic heterogeneity.
    Proceedings of the National Academy of Sciences of the United States of America, 2015, Jan-20, Volume: 112, Issue:3

    Topics: Antineoplastic Agents; Brain Neoplasms; Cell Line, Tumor; Dacarbazine; Drug Resistance, Neoplasm; Gl

2015
Salvage therapy with lomustine for temozolomide refractory recurrent anaplastic astrocytoma: a retrospective study.
    Journal of neuro-oncology, 2015, Volume: 122, Issue:2

    Topics: Adult; Antineoplastic Agents, Alkylating; Astrocytoma; Biomarkers, Tumor; Brain Neoplasms; Dacarbazi

2015
Salvage therapy with lomustine for temozolomide refractory recurrent anaplastic astrocytoma: a retrospective study.
    Journal of neuro-oncology, 2015, Volume: 122, Issue:2

    Topics: Adult; Antineoplastic Agents, Alkylating; Astrocytoma; Biomarkers, Tumor; Brain Neoplasms; Dacarbazi

2015
Salvage therapy with lomustine for temozolomide refractory recurrent anaplastic astrocytoma: a retrospective study.
    Journal of neuro-oncology, 2015, Volume: 122, Issue:2

    Topics: Adult; Antineoplastic Agents, Alkylating; Astrocytoma; Biomarkers, Tumor; Brain Neoplasms; Dacarbazi

2015
Erastin sensitizes glioblastoma cells to temozolomide by restraining xCT and cystathionine-γ-lyase function.
    Oncology reports, 2015, Volume: 33, Issue:3

    Topics: Amino Acid Transport System y+; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocol

2015
Erastin sensitizes glioblastoma cells to temozolomide by restraining xCT and cystathionine-γ-lyase function.
    Oncology reports, 2015, Volume: 33, Issue:3

    Topics: Amino Acid Transport System y+; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocol

2015
Erastin sensitizes glioblastoma cells to temozolomide by restraining xCT and cystathionine-γ-lyase function.
    Oncology reports, 2015, Volume: 33, Issue:3

    Topics: Amino Acid Transport System y+; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocol

2015
Effects of hnRNP A2/B1 Knockdown on Inhibition of Glioblastoma Cell Invasion, Growth and Survival.
    Molecular neurobiology, 2016, Volume: 53, Issue:2

    Topics: Brain Neoplasms; Cell Adhesion; Cell Line, Tumor; Cell Proliferation; Cell Survival; Dacarbazine; Dr

2016
Effects of hnRNP A2/B1 Knockdown on Inhibition of Glioblastoma Cell Invasion, Growth and Survival.
    Molecular neurobiology, 2016, Volume: 53, Issue:2

    Topics: Brain Neoplasms; Cell Adhesion; Cell Line, Tumor; Cell Proliferation; Cell Survival; Dacarbazine; Dr

2016
Effects of hnRNP A2/B1 Knockdown on Inhibition of Glioblastoma Cell Invasion, Growth and Survival.
    Molecular neurobiology, 2016, Volume: 53, Issue:2

    Topics: Brain Neoplasms; Cell Adhesion; Cell Line, Tumor; Cell Proliferation; Cell Survival; Dacarbazine; Dr

2016
Diffusion and perfusion MRI to differentiate treatment-related changes including pseudoprogression from recurrent tumors in high-grade gliomas with histopathologic evidence.
    AJNR. American journal of neuroradiology, 2015, Volume: 36, Issue:5

    Topics: Aged; Antineoplastic Agents; Brain Diseases; Brain Neoplasms; Dacarbazine; Disease Progression; Fema

2015
Diffusion and perfusion MRI to differentiate treatment-related changes including pseudoprogression from recurrent tumors in high-grade gliomas with histopathologic evidence.
    AJNR. American journal of neuroradiology, 2015, Volume: 36, Issue:5

    Topics: Aged; Antineoplastic Agents; Brain Diseases; Brain Neoplasms; Dacarbazine; Disease Progression; Fema

2015
Diffusion and perfusion MRI to differentiate treatment-related changes including pseudoprogression from recurrent tumors in high-grade gliomas with histopathologic evidence.
    AJNR. American journal of neuroradiology, 2015, Volume: 36, Issue:5

    Topics: Aged; Antineoplastic Agents; Brain Diseases; Brain Neoplasms; Dacarbazine; Disease Progression; Fema

2015
Temozolomide resistance in glioblastoma occurs by miRNA-9-targeted PTCH1, independent of sonic hedgehog level.
    Oncotarget, 2015, Jan-20, Volume: 6, Issue:2

    Topics: 3' Untranslated Regions; Animals; Antineoplastic Agents, Alkylating; ATP Binding Cassette Transporte

2015
Temozolomide resistance in glioblastoma occurs by miRNA-9-targeted PTCH1, independent of sonic hedgehog level.
    Oncotarget, 2015, Jan-20, Volume: 6, Issue:2

    Topics: 3' Untranslated Regions; Animals; Antineoplastic Agents, Alkylating; ATP Binding Cassette Transporte

2015
Temozolomide resistance in glioblastoma occurs by miRNA-9-targeted PTCH1, independent of sonic hedgehog level.
    Oncotarget, 2015, Jan-20, Volume: 6, Issue:2

    Topics: 3' Untranslated Regions; Animals; Antineoplastic Agents, Alkylating; ATP Binding Cassette Transporte

2015
Outcome of salvage treatment for recurrent glioblastoma.
    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2015, Volume: 22, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherap

2015
Outcome of salvage treatment for recurrent glioblastoma.
    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2015, Volume: 22, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherap

2015
Outcome of salvage treatment for recurrent glioblastoma.
    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2015, Volume: 22, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherap

2015
Targeting miR-381-NEFL axis sensitizes glioblastoma cells to temozolomide by regulating stemness factors and multidrug resistance factors.
    Oncotarget, 2015, Feb-20, Volume: 6, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Cell Movement; Cell Proliferat

2015
Targeting miR-381-NEFL axis sensitizes glioblastoma cells to temozolomide by regulating stemness factors and multidrug resistance factors.
    Oncotarget, 2015, Feb-20, Volume: 6, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Cell Movement; Cell Proliferat

2015
Targeting miR-381-NEFL axis sensitizes glioblastoma cells to temozolomide by regulating stemness factors and multidrug resistance factors.
    Oncotarget, 2015, Feb-20, Volume: 6, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Cell Movement; Cell Proliferat

2015
Biological tumor volume in 18FET-PET before radiochemotherapy correlates with survival in GBM.
    Neurology, 2015, Feb-17, Volume: 84, Issue:7

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain; Brain Neoplasms; Chemoradiotherapy; Combined

2015
Biological tumor volume in 18FET-PET before radiochemotherapy correlates with survival in GBM.
    Neurology, 2015, Feb-17, Volume: 84, Issue:7

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain; Brain Neoplasms; Chemoradiotherapy; Combined

2015
Biological tumor volume in 18FET-PET before radiochemotherapy correlates with survival in GBM.
    Neurology, 2015, Feb-17, Volume: 84, Issue:7

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain; Brain Neoplasms; Chemoradiotherapy; Combined

2015
Clinical benefit in recurrent glioblastoma from adjuvant NovoTTF-100A and TCCC after temozolomide and bevacizumab failure: a preliminary observation.
    Cancer medicine, 2015, Volume: 4, Issue:3

    Topics: Adult; Aged; Angiogenesis Inhibitors; Antimetabolites, Antineoplastic; Antineoplastic Agents, Alkyla

2015
Clinical benefit in recurrent glioblastoma from adjuvant NovoTTF-100A and TCCC after temozolomide and bevacizumab failure: a preliminary observation.
    Cancer medicine, 2015, Volume: 4, Issue:3

    Topics: Adult; Aged; Angiogenesis Inhibitors; Antimetabolites, Antineoplastic; Antineoplastic Agents, Alkyla

2015
Clinical benefit in recurrent glioblastoma from adjuvant NovoTTF-100A and TCCC after temozolomide and bevacizumab failure: a preliminary observation.
    Cancer medicine, 2015, Volume: 4, Issue:3

    Topics: Adult; Aged; Angiogenesis Inhibitors; Antimetabolites, Antineoplastic; Antineoplastic Agents, Alkyla

2015
p53 upregulated modulator of apoptosis sensitizes drug-resistant U251 glioblastoma stem cells to temozolomide through enhanced apoptosis.
    Molecular medicine reports, 2015, Volume: 11, Issue:6

    Topics: AC133 Antigen; Animals; Antigens, CD; Antineoplastic Agents, Alkylating; Apoptosis; Apoptosis Regula

2015
p53 upregulated modulator of apoptosis sensitizes drug-resistant U251 glioblastoma stem cells to temozolomide through enhanced apoptosis.
    Molecular medicine reports, 2015, Volume: 11, Issue:6

    Topics: AC133 Antigen; Animals; Antigens, CD; Antineoplastic Agents, Alkylating; Apoptosis; Apoptosis Regula

2015
p53 upregulated modulator of apoptosis sensitizes drug-resistant U251 glioblastoma stem cells to temozolomide through enhanced apoptosis.
    Molecular medicine reports, 2015, Volume: 11, Issue:6

    Topics: AC133 Antigen; Animals; Antigens, CD; Antineoplastic Agents, Alkylating; Apoptosis; Apoptosis Regula

2015
Glioma cells escaped from cytotoxicity of temozolomide and vincristine by communicating with human astrocytes.
    Medical oncology (Northwood, London, England), 2015, Volume: 32, Issue:3

    Topics: Antineoplastic Agents; Apoptosis; Astrocytes; Brain Neoplasms; Calcium; Cell Communication; Cocultur

2015
Glioma cells escaped from cytotoxicity of temozolomide and vincristine by communicating with human astrocytes.
    Medical oncology (Northwood, London, England), 2015, Volume: 32, Issue:3

    Topics: Antineoplastic Agents; Apoptosis; Astrocytes; Brain Neoplasms; Calcium; Cell Communication; Cocultur

2015
Glioma cells escaped from cytotoxicity of temozolomide and vincristine by communicating with human astrocytes.
    Medical oncology (Northwood, London, England), 2015, Volume: 32, Issue:3

    Topics: Antineoplastic Agents; Apoptosis; Astrocytes; Brain Neoplasms; Calcium; Cell Communication; Cocultur

2015
Impact of 1p/19q codeletion and histology on outcomes of anaplastic gliomas treated with radiation therapy and temozolomide.
    International journal of radiation oncology, biology, physics, 2015, Feb-01, Volume: 91, Issue:2

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Brai

2015
Impact of 1p/19q codeletion and histology on outcomes of anaplastic gliomas treated with radiation therapy and temozolomide.
    International journal of radiation oncology, biology, physics, 2015, Feb-01, Volume: 91, Issue:2

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Brai

2015
Impact of 1p/19q codeletion and histology on outcomes of anaplastic gliomas treated with radiation therapy and temozolomide.
    International journal of radiation oncology, biology, physics, 2015, Feb-01, Volume: 91, Issue:2

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Brai

2015
Combined anti-Galectin-1 and anti-EGFR siRNA-loaded chitosan-lipid nanocapsules decrease temozolomide resistance in glioblastoma: in vivo evaluation.
    International journal of pharmaceutics, 2015, Mar-15, Volume: 481, Issue:1-2

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Chitosan; Dacarbazine

2015
Combined anti-Galectin-1 and anti-EGFR siRNA-loaded chitosan-lipid nanocapsules decrease temozolomide resistance in glioblastoma: in vivo evaluation.
    International journal of pharmaceutics, 2015, Mar-15, Volume: 481, Issue:1-2

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Chitosan; Dacarbazine

2015
Combined anti-Galectin-1 and anti-EGFR siRNA-loaded chitosan-lipid nanocapsules decrease temozolomide resistance in glioblastoma: in vivo evaluation.
    International journal of pharmaceutics, 2015, Mar-15, Volume: 481, Issue:1-2

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Chitosan; Dacarbazine

2015
The effect of valproic acid in combination with irradiation and temozolomide on primary human glioblastoma cells.
    Journal of neuro-oncology, 2015, Volume: 122, Issue:2

    Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Cel

2015
The effect of valproic acid in combination with irradiation and temozolomide on primary human glioblastoma cells.
    Journal of neuro-oncology, 2015, Volume: 122, Issue:2

    Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Cel

2015
The effect of valproic acid in combination with irradiation and temozolomide on primary human glioblastoma cells.
    Journal of neuro-oncology, 2015, Volume: 122, Issue:2

    Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Cel

2015
Elderly patients with glioblastoma multiforme treated with concurrent temozolomide and standard- versus abbreviated-course radiotherapy.
    The Permanente journal, 2015,Winter, Volume: 19, Issue:1

    Topics: Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Thera

2015
Elderly patients with glioblastoma multiforme treated with concurrent temozolomide and standard- versus abbreviated-course radiotherapy.
    The Permanente journal, 2015,Winter, Volume: 19, Issue:1

    Topics: Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Thera

2015
Elderly patients with glioblastoma multiforme treated with concurrent temozolomide and standard- versus abbreviated-course radiotherapy.
    The Permanente journal, 2015,Winter, Volume: 19, Issue:1

    Topics: Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Thera

2015
Over-expression of tetraspanin 8 in malignant glioma regulates tumor cell progression.
    Biochemical and biophysical research communications, 2015, Mar-13, Volume: 458, Issue:3

    Topics: Antineoplastic Agents, Alkylating; Apoptosis; Brain; Brain Neoplasms; Cell Line, Tumor; Dacarbazine;

2015
Over-expression of tetraspanin 8 in malignant glioma regulates tumor cell progression.
    Biochemical and biophysical research communications, 2015, Mar-13, Volume: 458, Issue:3

    Topics: Antineoplastic Agents, Alkylating; Apoptosis; Brain; Brain Neoplasms; Cell Line, Tumor; Dacarbazine;

2015
Over-expression of tetraspanin 8 in malignant glioma regulates tumor cell progression.
    Biochemical and biophysical research communications, 2015, Mar-13, Volume: 458, Issue:3

    Topics: Antineoplastic Agents, Alkylating; Apoptosis; Brain; Brain Neoplasms; Cell Line, Tumor; Dacarbazine;

2015
Glioma cell VEGFR-2 confers resistance to chemotherapeutic and antiangiogenic treatments in PTEN-deficient glioblastoma.
    Oncotarget, 2015, Oct-13, Volume: 6, Issue:31

    Topics: Angiogenesis Inhibitors; Animals; Bevacizumab; Brain Neoplasms; Cell Line, Tumor; Cell Movement; Cel

2015
Glioma cell VEGFR-2 confers resistance to chemotherapeutic and antiangiogenic treatments in PTEN-deficient glioblastoma.
    Oncotarget, 2015, Oct-13, Volume: 6, Issue:31

    Topics: Angiogenesis Inhibitors; Animals; Bevacizumab; Brain Neoplasms; Cell Line, Tumor; Cell Movement; Cel

2015
Glioma cell VEGFR-2 confers resistance to chemotherapeutic and antiangiogenic treatments in PTEN-deficient glioblastoma.
    Oncotarget, 2015, Oct-13, Volume: 6, Issue:31

    Topics: Angiogenesis Inhibitors; Animals; Bevacizumab; Brain Neoplasms; Cell Line, Tumor; Cell Movement; Cel

2015
Imp2 regulates GBM progression by activating IGF2/PI3K/Akt pathway.
    Cancer biology & therapy, 2015, Volume: 16, Issue:4

    Topics: Brain Neoplasms; Cell Line, Tumor; Cell Movement; Cell Proliferation; Dacarbazine; Epithelial-Mesenc

2015
Imp2 regulates GBM progression by activating IGF2/PI3K/Akt pathway.
    Cancer biology & therapy, 2015, Volume: 16, Issue:4

    Topics: Brain Neoplasms; Cell Line, Tumor; Cell Movement; Cell Proliferation; Dacarbazine; Epithelial-Mesenc

2015
Imp2 regulates GBM progression by activating IGF2/PI3K/Akt pathway.
    Cancer biology & therapy, 2015, Volume: 16, Issue:4

    Topics: Brain Neoplasms; Cell Line, Tumor; Cell Movement; Cell Proliferation; Dacarbazine; Epithelial-Mesenc

2015
Prognostic value of MGMT promoter status in non-resectable glioblastoma after adjuvant therapy.
    Clinical neurology and neurosurgery, 2015, Volume: 132

    Topics: Aged; Antineoplastic Agents, Alkylating; Biomarkers, Tumor; Biopsy, Needle; Brain Neoplasms; Chemoth

2015
Prognostic value of MGMT promoter status in non-resectable glioblastoma after adjuvant therapy.
    Clinical neurology and neurosurgery, 2015, Volume: 132

    Topics: Aged; Antineoplastic Agents, Alkylating; Biomarkers, Tumor; Biopsy, Needle; Brain Neoplasms; Chemoth

2015
Prognostic value of MGMT promoter status in non-resectable glioblastoma after adjuvant therapy.
    Clinical neurology and neurosurgery, 2015, Volume: 132

    Topics: Aged; Antineoplastic Agents, Alkylating; Biomarkers, Tumor; Biopsy, Needle; Brain Neoplasms; Chemoth

2015
Evolution of DNA repair defects during malignant progression of low-grade gliomas after temozolomide treatment.
    Acta neuropathologica, 2015, Volume: 129, Issue:4

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cohort Studies; Dacarbazine; Disease Progression

2015
Evolution of DNA repair defects during malignant progression of low-grade gliomas after temozolomide treatment.
    Acta neuropathologica, 2015, Volume: 129, Issue:4

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cohort Studies; Dacarbazine; Disease Progression

2015
Evolution of DNA repair defects during malignant progression of low-grade gliomas after temozolomide treatment.
    Acta neuropathologica, 2015, Volume: 129, Issue:4

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cohort Studies; Dacarbazine; Disease Progression

2015
Glioblastoma adaptation traced through decline of an IDH1 clonal driver and macro-evolution of a double-minute chromosome.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2015, Volume: 26, Issue:5

    Topics: Adult; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant; Chromosomes, Huma

2015
Glioblastoma adaptation traced through decline of an IDH1 clonal driver and macro-evolution of a double-minute chromosome.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2015, Volume: 26, Issue:5

    Topics: Adult; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant; Chromosomes, Huma

2015
Glioblastoma adaptation traced through decline of an IDH1 clonal driver and macro-evolution of a double-minute chromosome.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2015, Volume: 26, Issue:5

    Topics: Adult; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant; Chromosomes, Huma

2015
Genomically amplified Akt3 activates DNA repair pathway and promotes glioma progression.
    Proceedings of the National Academy of Sciences of the United States of America, 2015, Mar-17, Volume: 112, Issue:11

    Topics: Animals; Brain Neoplasms; Cell Line, Tumor; Dacarbazine; Disease Progression; DNA Damage; DNA Repair

2015
Genomically amplified Akt3 activates DNA repair pathway and promotes glioma progression.
    Proceedings of the National Academy of Sciences of the United States of America, 2015, Mar-17, Volume: 112, Issue:11

    Topics: Animals; Brain Neoplasms; Cell Line, Tumor; Dacarbazine; Disease Progression; DNA Damage; DNA Repair

2015
Genomically amplified Akt3 activates DNA repair pathway and promotes glioma progression.
    Proceedings of the National Academy of Sciences of the United States of America, 2015, Mar-17, Volume: 112, Issue:11

    Topics: Animals; Brain Neoplasms; Cell Line, Tumor; Dacarbazine; Disease Progression; DNA Damage; DNA Repair

2015
EGFR amplified and overexpressing glioblastomas and association with better response to adjuvant metronomic temozolomide.
    Journal of the National Cancer Institute, 2015, Volume: 107, Issue:5

    Topics: Administration, Metronomic; Adult; Analysis of Variance; Antineoplastic Agents, Alkylating; Brain Ne

2015
EGFR amplified and overexpressing glioblastomas and association with better response to adjuvant metronomic temozolomide.
    Journal of the National Cancer Institute, 2015, Volume: 107, Issue:5

    Topics: Administration, Metronomic; Adult; Analysis of Variance; Antineoplastic Agents, Alkylating; Brain Ne

2015
EGFR amplified and overexpressing glioblastomas and association with better response to adjuvant metronomic temozolomide.
    Journal of the National Cancer Institute, 2015, Volume: 107, Issue:5

    Topics: Administration, Metronomic; Adult; Analysis of Variance; Antineoplastic Agents, Alkylating; Brain Ne

2015
Coexpression analysis of CD133 and CD44 identifies proneural and mesenchymal subtypes of glioblastoma multiforme.
    Oncotarget, 2015, Mar-20, Volume: 6, Issue:8

    Topics: AC133 Antigen; Antigens, CD; Biomarkers, Tumor; Brain Neoplasms; Cell Proliferation; Dacarbazine; Ge

2015
Coexpression analysis of CD133 and CD44 identifies proneural and mesenchymal subtypes of glioblastoma multiforme.
    Oncotarget, 2015, Mar-20, Volume: 6, Issue:8

    Topics: AC133 Antigen; Antigens, CD; Biomarkers, Tumor; Brain Neoplasms; Cell Proliferation; Dacarbazine; Ge

2015
Coexpression analysis of CD133 and CD44 identifies proneural and mesenchymal subtypes of glioblastoma multiforme.
    Oncotarget, 2015, Mar-20, Volume: 6, Issue:8

    Topics: AC133 Antigen; Antigens, CD; Biomarkers, Tumor; Brain Neoplasms; Cell Proliferation; Dacarbazine; Ge

2015
Treatment results and prognostic factors for intracranial nongerminomatous germ cell tumors: single institute experience.
    Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 2015, Volume: 31, Issue:5

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Brain Neoplasms; Chemotherapy

2015
Treatment results and prognostic factors for intracranial nongerminomatous germ cell tumors: single institute experience.
    Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 2015, Volume: 31, Issue:5

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Brain Neoplasms; Chemotherapy

2015
Treatment results and prognostic factors for intracranial nongerminomatous germ cell tumors: single institute experience.
    Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 2015, Volume: 31, Issue:5

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Brain Neoplasms; Chemotherapy

2015
The effect of silibinin in enhancing toxicity of temozolomide and etoposide in p53 and PTEN-mutated resistant glioma cell lines.
    Anticancer research, 2015, Volume: 35, Issue:3

    Topics: Antineoplastic Agents; Brain Neoplasms; Cell Line, Tumor; Dacarbazine; Drug Resistance, Neoplasm; Dr

2015
The effect of silibinin in enhancing toxicity of temozolomide and etoposide in p53 and PTEN-mutated resistant glioma cell lines.
    Anticancer research, 2015, Volume: 35, Issue:3

    Topics: Antineoplastic Agents; Brain Neoplasms; Cell Line, Tumor; Dacarbazine; Drug Resistance, Neoplasm; Dr

2015
The effect of silibinin in enhancing toxicity of temozolomide and etoposide in p53 and PTEN-mutated resistant glioma cell lines.
    Anticancer research, 2015, Volume: 35, Issue:3

    Topics: Antineoplastic Agents; Brain Neoplasms; Cell Line, Tumor; Dacarbazine; Drug Resistance, Neoplasm; Dr

2015
Decitabine nanoconjugate sensitizes human glioblastoma cells to temozolomide.
    Molecular pharmaceutics, 2015, Apr-06, Volume: 12, Issue:4

    Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents, Alkylating; Apoptosis; Azacitidine; Biocompa

2015
Decitabine nanoconjugate sensitizes human glioblastoma cells to temozolomide.
    Molecular pharmaceutics, 2015, Apr-06, Volume: 12, Issue:4

    Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents, Alkylating; Apoptosis; Azacitidine; Biocompa

2015
Decitabine nanoconjugate sensitizes human glioblastoma cells to temozolomide.
    Molecular pharmaceutics, 2015, Apr-06, Volume: 12, Issue:4

    Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents, Alkylating; Apoptosis; Azacitidine; Biocompa

2015
Temozolomide nanoparticles for targeted glioblastoma therapy.
    ACS applied materials & interfaces, 2015, Apr-01, Volume: 7, Issue:12

    Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Cell Line, Tumor; Dacarbazine; Drug Carriers; Drug

2015
Temozolomide nanoparticles for targeted glioblastoma therapy.
    ACS applied materials & interfaces, 2015, Apr-01, Volume: 7, Issue:12

    Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Cell Line, Tumor; Dacarbazine; Drug Carriers; Drug

2015
Temozolomide nanoparticles for targeted glioblastoma therapy.
    ACS applied materials & interfaces, 2015, Apr-01, Volume: 7, Issue:12

    Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Cell Line, Tumor; Dacarbazine; Drug Carriers; Drug

2015
A transcriptomic signature mediated by HOXA9 promotes human glioblastoma initiation, aggressiveness and resistance to temozolomide.
    Oncotarget, 2015, Apr-10, Volume: 6, Issue:10

    Topics: Animals; Brain Neoplasms; Cell Proliferation; Dacarbazine; Gene Expression; Glioblastoma; Homeodomai

2015
A transcriptomic signature mediated by HOXA9 promotes human glioblastoma initiation, aggressiveness and resistance to temozolomide.
    Oncotarget, 2015, Apr-10, Volume: 6, Issue:10

    Topics: Animals; Brain Neoplasms; Cell Proliferation; Dacarbazine; Gene Expression; Glioblastoma; Homeodomai

2015
A transcriptomic signature mediated by HOXA9 promotes human glioblastoma initiation, aggressiveness and resistance to temozolomide.
    Oncotarget, 2015, Apr-10, Volume: 6, Issue:10

    Topics: Animals; Brain Neoplasms; Cell Proliferation; Dacarbazine; Gene Expression; Glioblastoma; Homeodomai

2015
Elimination of cancer stem-like cells and potentiation of temozolomide sensitivity by Honokiol in glioblastoma multiforme cells.
    PloS one, 2015, Volume: 10, Issue:3

    Topics: Antineoplastic Agents; Apoptosis; Basic Helix-Loop-Helix Transcription Factors; Biphenyl Compounds;

2015
Elimination of cancer stem-like cells and potentiation of temozolomide sensitivity by Honokiol in glioblastoma multiforme cells.
    PloS one, 2015, Volume: 10, Issue:3

    Topics: Antineoplastic Agents; Apoptosis; Basic Helix-Loop-Helix Transcription Factors; Biphenyl Compounds;

2015
Elimination of cancer stem-like cells and potentiation of temozolomide sensitivity by Honokiol in glioblastoma multiforme cells.
    PloS one, 2015, Volume: 10, Issue:3

    Topics: Antineoplastic Agents; Apoptosis; Basic Helix-Loop-Helix Transcription Factors; Biphenyl Compounds;

2015
The evolving genomic landscape of recurrent gliomas.
    World neurosurgery, 2015, Volume: 83, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; DNA Helicases; Genomics; Glioma; Hu

2015
The evolving genomic landscape of recurrent gliomas.
    World neurosurgery, 2015, Volume: 83, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; DNA Helicases; Genomics; Glioma; Hu

2015
The evolving genomic landscape of recurrent gliomas.
    World neurosurgery, 2015, Volume: 83, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; DNA Helicases; Genomics; Glioma; Hu

2015
Post-surgical therapeutic approaches to glioblastoma patients submitted to biopsy (BA) or "partial" resection (PR): the possibilities to treat also them without renunciations. Study from the Brescia Neuro-Oncology Group.
    La Radiologia medica, 2015, Volume: 120, Issue:10

    Topics: Antineoplastic Agents, Alkylating; Biopsy; Brain Neoplasms; Dacarbazine; Glioblastoma; Humans; Middl

2015
Post-surgical therapeutic approaches to glioblastoma patients submitted to biopsy (BA) or "partial" resection (PR): the possibilities to treat also them without renunciations. Study from the Brescia Neuro-Oncology Group.
    La Radiologia medica, 2015, Volume: 120, Issue:10

    Topics: Antineoplastic Agents, Alkylating; Biopsy; Brain Neoplasms; Dacarbazine; Glioblastoma; Humans; Middl

2015
Post-surgical therapeutic approaches to glioblastoma patients submitted to biopsy (BA) or "partial" resection (PR): the possibilities to treat also them without renunciations. Study from the Brescia Neuro-Oncology Group.
    La Radiologia medica, 2015, Volume: 120, Issue:10

    Topics: Antineoplastic Agents, Alkylating; Biopsy; Brain Neoplasms; Dacarbazine; Glioblastoma; Humans; Middl

2015
Focused ultrasound with microbubbles increases temozolomide delivery in U87 transfected mice.
    Neurosurgery, 2015, Volume: 76, Issue:4

    Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Cell Line, Tumor; Dacarbazine; Disease Models, Anim

2015
Focused ultrasound with microbubbles increases temozolomide delivery in U87 transfected mice.
    Neurosurgery, 2015, Volume: 76, Issue:4

    Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Cell Line, Tumor; Dacarbazine; Disease Models, Anim

2015
Focused ultrasound with microbubbles increases temozolomide delivery in U87 transfected mice.
    Neurosurgery, 2015, Volume: 76, Issue:4

    Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Cell Line, Tumor; Dacarbazine; Disease Models, Anim

2015
Preclinical impact of bevacizumab on brain and tumor distribution of irinotecan and temozolomide.
    Journal of neuro-oncology, 2015, Volume: 122, Issue:2

    Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Phytogen

2015
Preclinical impact of bevacizumab on brain and tumor distribution of irinotecan and temozolomide.
    Journal of neuro-oncology, 2015, Volume: 122, Issue:2

    Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Phytogen

2015
Preclinical impact of bevacizumab on brain and tumor distribution of irinotecan and temozolomide.
    Journal of neuro-oncology, 2015, Volume: 122, Issue:2

    Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Phytogen

2015
Identification of imaging biomarkers for the assessment of tumour response to different treatments in a preclinical glioma model.
    European journal of nuclear medicine and molecular imaging, 2015, Volume: 42, Issue:7

    Topics: Animals; Antineoplastic Agents; Biomarkers, Tumor; Brain Neoplasms; Carbonic Anhydrases; Cell Line,

2015
Identification of imaging biomarkers for the assessment of tumour response to different treatments in a preclinical glioma model.
    European journal of nuclear medicine and molecular imaging, 2015, Volume: 42, Issue:7

    Topics: Animals; Antineoplastic Agents; Biomarkers, Tumor; Brain Neoplasms; Carbonic Anhydrases; Cell Line,

2015
Identification of imaging biomarkers for the assessment of tumour response to different treatments in a preclinical glioma model.
    European journal of nuclear medicine and molecular imaging, 2015, Volume: 42, Issue:7

    Topics: Animals; Antineoplastic Agents; Biomarkers, Tumor; Brain Neoplasms; Carbonic Anhydrases; Cell Line,

2015
Temozolomide and radiotherapy versus radiotherapy alone in high grade gliomas: a very long term comparative study and literature review.
    BioMed research international, 2015, Volume: 2015

    Topics: Adult; Aged; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Female; Glioma; Humans; Male;

2015
Temozolomide and radiotherapy versus radiotherapy alone in high grade gliomas: a very long term comparative study and literature review.
    BioMed research international, 2015, Volume: 2015

    Topics: Adult; Aged; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Female; Glioma; Humans; Male;

2015
Temozolomide and radiotherapy versus radiotherapy alone in high grade gliomas: a very long term comparative study and literature review.
    BioMed research international, 2015, Volume: 2015

    Topics: Adult; Aged; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Female; Glioma; Humans; Male;

2015
The metalloprotease-disintegrin ADAM8 contributes to temozolomide chemoresistance and enhanced invasiveness of human glioblastoma cells.
    Neuro-oncology, 2015, Volume: 17, Issue:11

    Topics: ADAM Proteins; Antineoplastic Agents; Blotting, Western; Brain Neoplasms; Cell Separation; Cell Surv

2015
The metalloprotease-disintegrin ADAM8 contributes to temozolomide chemoresistance and enhanced invasiveness of human glioblastoma cells.
    Neuro-oncology, 2015, Volume: 17, Issue:11

    Topics: ADAM Proteins; Antineoplastic Agents; Blotting, Western; Brain Neoplasms; Cell Separation; Cell Surv

2015
The metalloprotease-disintegrin ADAM8 contributes to temozolomide chemoresistance and enhanced invasiveness of human glioblastoma cells.
    Neuro-oncology, 2015, Volume: 17, Issue:11

    Topics: ADAM Proteins; Antineoplastic Agents; Blotting, Western; Brain Neoplasms; Cell Separation; Cell Surv

2015
Hypofractionated versus standard radiation therapy with or without temozolomide for older glioblastoma patients.
    International journal of radiation oncology, biology, physics, 2015, Jun-01, Volume: 92, Issue:2

    Topics: Age Factors; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazin

2015
Hypofractionated versus standard radiation therapy with or without temozolomide for older glioblastoma patients.
    International journal of radiation oncology, biology, physics, 2015, Jun-01, Volume: 92, Issue:2

    Topics: Age Factors; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazin

2015
Hypofractionated versus standard radiation therapy with or without temozolomide for older glioblastoma patients.
    International journal of radiation oncology, biology, physics, 2015, Jun-01, Volume: 92, Issue:2

    Topics: Age Factors; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazin

2015
Epithelial-to-mesenchymal transition in paired human primary and recurrent glioblastomas.
    International journal of oncology, 2015, Volume: 46, Issue:6

    Topics: Biomarkers, Tumor; Brain Neoplasms; Cell Line, Tumor; Dacarbazine; Epithelial-Mesenchymal Transition

2015
Epithelial-to-mesenchymal transition in paired human primary and recurrent glioblastomas.
    International journal of oncology, 2015, Volume: 46, Issue:6

    Topics: Biomarkers, Tumor; Brain Neoplasms; Cell Line, Tumor; Dacarbazine; Epithelial-Mesenchymal Transition

2015
Epithelial-to-mesenchymal transition in paired human primary and recurrent glioblastomas.
    International journal of oncology, 2015, Volume: 46, Issue:6

    Topics: Biomarkers, Tumor; Brain Neoplasms; Cell Line, Tumor; Dacarbazine; Epithelial-Mesenchymal Transition

2015
The Effect of Timing of Concurrent Chemoradiation in Patients With Newly Diagnosed Glioblastoma.
    Neurosurgery, 2015, Volume: 77, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Algorithms; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chem

2015
The Effect of Timing of Concurrent Chemoradiation in Patients With Newly Diagnosed Glioblastoma.
    Neurosurgery, 2015, Volume: 77, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Algorithms; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chem

2015
The Effect of Timing of Concurrent Chemoradiation in Patients With Newly Diagnosed Glioblastoma.
    Neurosurgery, 2015, Volume: 77, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Algorithms; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chem

2015
Recurrence of glioblastoma after radio-chemotherapy is associated with an angiogenic switch to the CXCL12-CXCR4 pathway.
    Oncotarget, 2015, May-10, Volume: 6, Issue:13

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Benzylamines; Brain Neoplasms; Chemokine

2015
Recurrence of glioblastoma after radio-chemotherapy is associated with an angiogenic switch to the CXCL12-CXCR4 pathway.
    Oncotarget, 2015, May-10, Volume: 6, Issue:13

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Benzylamines; Brain Neoplasms; Chemokine

2015
Recurrence of glioblastoma after radio-chemotherapy is associated with an angiogenic switch to the CXCL12-CXCR4 pathway.
    Oncotarget, 2015, May-10, Volume: 6, Issue:13

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Benzylamines; Brain Neoplasms; Chemokine

2015
Silencing of R-Spondin1 increases radiosensitivity of glioma cells.
    Oncotarget, 2015, Volume: 6, Issue:12

    Topics: Adult; Aged; Aged, 80 and over; Animals; Antineoplastic Agents; Antineoplastic Agents, Alkylating; A

2015
Silencing of R-Spondin1 increases radiosensitivity of glioma cells.
    Oncotarget, 2015, Volume: 6, Issue:12

    Topics: Adult; Aged; Aged, 80 and over; Animals; Antineoplastic Agents; Antineoplastic Agents, Alkylating; A

2015
Silencing of R-Spondin1 increases radiosensitivity of glioma cells.
    Oncotarget, 2015, Volume: 6, Issue:12

    Topics: Adult; Aged; Aged, 80 and over; Animals; Antineoplastic Agents; Antineoplastic Agents, Alkylating; A

2015
Metformin inhibits growth of human glioblastoma cells and enhances therapeutic response.
    PloS one, 2015, Volume: 10, Issue:4

    Topics: Adenylate Kinase; Animals; Apoptosis; Autophagy; Brain Neoplasms; Cell Division; Cell Line, Tumor; D

2015
Metformin inhibits growth of human glioblastoma cells and enhances therapeutic response.
    PloS one, 2015, Volume: 10, Issue:4

    Topics: Adenylate Kinase; Animals; Apoptosis; Autophagy; Brain Neoplasms; Cell Division; Cell Line, Tumor; D

2015
Metformin inhibits growth of human glioblastoma cells and enhances therapeutic response.
    PloS one, 2015, Volume: 10, Issue:4

    Topics: Adenylate Kinase; Animals; Apoptosis; Autophagy; Brain Neoplasms; Cell Division; Cell Line, Tumor; D

2015
MicroRNA profiling of Chinese primary glioblastoma reveals a temozolomide-chemoresistant subtype.
    Oncotarget, 2015, May-10, Volume: 6, Issue:13

    Topics: Adult; Antineoplastic Agents, Alkylating; Asian People; Biomarkers, Tumor; Brain Neoplasms; China; C

2015
MicroRNA profiling of Chinese primary glioblastoma reveals a temozolomide-chemoresistant subtype.
    Oncotarget, 2015, May-10, Volume: 6, Issue:13

    Topics: Adult; Antineoplastic Agents, Alkylating; Asian People; Biomarkers, Tumor; Brain Neoplasms; China; C

2015
MicroRNA profiling of Chinese primary glioblastoma reveals a temozolomide-chemoresistant subtype.
    Oncotarget, 2015, May-10, Volume: 6, Issue:13

    Topics: Adult; Antineoplastic Agents, Alkylating; Asian People; Biomarkers, Tumor; Brain Neoplasms; China; C

2015
ABT-888 enhances cytotoxic effects of temozolomide independent of MGMT status in serum free cultured glioma cells.
    Journal of translational medicine, 2015, Feb-26, Volume: 13

    Topics: Apoptosis; Autophagy; Benzimidazoles; Brain Neoplasms; Culture Media, Serum-Free; Dacarbazine; DNA B

2015
ABT-888 enhances cytotoxic effects of temozolomide independent of MGMT status in serum free cultured glioma cells.
    Journal of translational medicine, 2015, Feb-26, Volume: 13

    Topics: Apoptosis; Autophagy; Benzimidazoles; Brain Neoplasms; Culture Media, Serum-Free; Dacarbazine; DNA B

2015
ABT-888 enhances cytotoxic effects of temozolomide independent of MGMT status in serum free cultured glioma cells.
    Journal of translational medicine, 2015, Feb-26, Volume: 13

    Topics: Apoptosis; Autophagy; Benzimidazoles; Brain Neoplasms; Culture Media, Serum-Free; Dacarbazine; DNA B

2015
Combined treatment of Nimotuzumab and rapamycin is effective against temozolomide-resistant human gliomas regardless of the EGFR mutation status.
    BMC cancer, 2015, Apr-11, Volume: 15

    Topics: Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Brain

2015
Combined treatment of Nimotuzumab and rapamycin is effective against temozolomide-resistant human gliomas regardless of the EGFR mutation status.
    BMC cancer, 2015, Apr-11, Volume: 15

    Topics: Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Brain

2015
Combined treatment of Nimotuzumab and rapamycin is effective against temozolomide-resistant human gliomas regardless of the EGFR mutation status.
    BMC cancer, 2015, Apr-11, Volume: 15

    Topics: Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Brain

2015
The DNA damage/repair cascade in glioblastoma cell lines after chemotherapeutic agent treatment.
    International journal of oncology, 2015, Volume: 46, Issue:6

    Topics: Antineoplastic Agents; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Dacarbazine

2015
The DNA damage/repair cascade in glioblastoma cell lines after chemotherapeutic agent treatment.
    International journal of oncology, 2015, Volume: 46, Issue:6

    Topics: Antineoplastic Agents; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Dacarbazine

2015
The DNA damage/repair cascade in glioblastoma cell lines after chemotherapeutic agent treatment.
    International journal of oncology, 2015, Volume: 46, Issue:6

    Topics: Antineoplastic Agents; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Dacarbazine

2015
Amino acid PET tracers are reliable markers of treatment responses to single-agent or combination therapies including temozolomide, interferon-β, and/or bevacizumab for glioblastoma.
    Nuclear medicine and biology, 2015, Volume: 42, Issue:7

    Topics: Amino Acids; Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bevaciz

2015
Amino acid PET tracers are reliable markers of treatment responses to single-agent or combination therapies including temozolomide, interferon-β, and/or bevacizumab for glioblastoma.
    Nuclear medicine and biology, 2015, Volume: 42, Issue:7

    Topics: Amino Acids; Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bevaciz

2015
Amino acid PET tracers are reliable markers of treatment responses to single-agent or combination therapies including temozolomide, interferon-β, and/or bevacizumab for glioblastoma.
    Nuclear medicine and biology, 2015, Volume: 42, Issue:7

    Topics: Amino Acids; Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bevaciz

2015
The MGMT promoter SNP rs16906252 is a risk factor for MGMT methylation in glioblastoma and is predictive of response to temozolomide.
    Neuro-oncology, 2015, Volume: 17, Issue:12

    Topics: Adult; Aged; Aged, 80 and over; Alleles; Antineoplastic Agents, Alkylating; Biomarkers; Brain Neopla

2015
The MGMT promoter SNP rs16906252 is a risk factor for MGMT methylation in glioblastoma and is predictive of response to temozolomide.
    Neuro-oncology, 2015, Volume: 17, Issue:12

    Topics: Adult; Aged; Aged, 80 and over; Alleles; Antineoplastic Agents, Alkylating; Biomarkers; Brain Neopla

2015
The MGMT promoter SNP rs16906252 is a risk factor for MGMT methylation in glioblastoma and is predictive of response to temozolomide.
    Neuro-oncology, 2015, Volume: 17, Issue:12

    Topics: Adult; Aged; Aged, 80 and over; Alleles; Antineoplastic Agents, Alkylating; Biomarkers; Brain Neopla

2015
Feasibility of the EORTC/NCIC Trial Protocol in a Neurosurgical Outpatient Unit: The Case for Neurosurgical Neuro-Oncology.
    Journal of neurological surgery. Part A, Central European neurosurgery, 2015, Volume: 76, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Ambulatory Care; Antineoplastic Agents, Alkylating; Brain Neoplasms;

2015
Feasibility of the EORTC/NCIC Trial Protocol in a Neurosurgical Outpatient Unit: The Case for Neurosurgical Neuro-Oncology.
    Journal of neurological surgery. Part A, Central European neurosurgery, 2015, Volume: 76, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Ambulatory Care; Antineoplastic Agents, Alkylating; Brain Neoplasms;

2015
Feasibility of the EORTC/NCIC Trial Protocol in a Neurosurgical Outpatient Unit: The Case for Neurosurgical Neuro-Oncology.
    Journal of neurological surgery. Part A, Central European neurosurgery, 2015, Volume: 76, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Ambulatory Care; Antineoplastic Agents, Alkylating; Brain Neoplasms;

2015
Risk factors for glioblastoma therapy associated complications.
    Clinical neurology and neurosurgery, 2015, Volume: 134

    Topics: Age Factors; Antineoplastic Agents; Brain Neoplasms; Chemoradiotherapy, Adjuvant; Cohort Studies; Da

2015
Risk factors for glioblastoma therapy associated complications.
    Clinical neurology and neurosurgery, 2015, Volume: 134

    Topics: Age Factors; Antineoplastic Agents; Brain Neoplasms; Chemoradiotherapy, Adjuvant; Cohort Studies; Da

2015
Risk factors for glioblastoma therapy associated complications.
    Clinical neurology and neurosurgery, 2015, Volume: 134

    Topics: Age Factors; Antineoplastic Agents; Brain Neoplasms; Chemoradiotherapy, Adjuvant; Cohort Studies; Da

2015
SEL1L SNP rs12435998, a predictor of glioblastoma survival and response to radio-chemotherapy.
    Oncotarget, 2015, May-20, Volume: 6, Issue:14

    Topics: Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Blotting, Western; Brain Neoplasm

2015
SEL1L SNP rs12435998, a predictor of glioblastoma survival and response to radio-chemotherapy.
    Oncotarget, 2015, May-20, Volume: 6, Issue:14

    Topics: Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Blotting, Western; Brain Neoplasm

2015
SEL1L SNP rs12435998, a predictor of glioblastoma survival and response to radio-chemotherapy.
    Oncotarget, 2015, May-20, Volume: 6, Issue:14

    Topics: Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Blotting, Western; Brain Neoplasm

2015
Treating anaplastic oligodendrogliomas and WHO grade 2 gliomas: PCV or temozolomide? The case for PCV.
    Oncology (Williston Park, N.Y.), 2015, Volume: 29, Issue:4

    Topics: Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms;

2015
Treating anaplastic oligodendrogliomas and WHO grade 2 gliomas: PCV or temozolomide? The case for PCV.
    Oncology (Williston Park, N.Y.), 2015, Volume: 29, Issue:4

    Topics: Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms;

2015
Treating anaplastic oligodendrogliomas and WHO grade 2 gliomas: PCV or temozolomide? The case for PCV.
    Oncology (Williston Park, N.Y.), 2015, Volume: 29, Issue:4

    Topics: Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms;

2015
Combination of the multipotent mesenchymal stromal cell transplantation with administration of temozolomide increases survival of rats with experimental glioblastoma.
    Molecular medicine reports, 2015, Volume: 12, Issue:2

    Topics: Animals; Brain Neoplasms; Cell Line, Tumor; Combined Modality Therapy; Dacarbazine; Disease Models,

2015
Combination of the multipotent mesenchymal stromal cell transplantation with administration of temozolomide increases survival of rats with experimental glioblastoma.
    Molecular medicine reports, 2015, Volume: 12, Issue:2

    Topics: Animals; Brain Neoplasms; Cell Line, Tumor; Combined Modality Therapy; Dacarbazine; Disease Models,

2015
Combination of the multipotent mesenchymal stromal cell transplantation with administration of temozolomide increases survival of rats with experimental glioblastoma.
    Molecular medicine reports, 2015, Volume: 12, Issue:2

    Topics: Animals; Brain Neoplasms; Cell Line, Tumor; Combined Modality Therapy; Dacarbazine; Disease Models,

2015
Chip-based analysis of exosomal mRNA mediating drug resistance in glioblastoma.
    Nature communications, 2015, May-11, Volume: 6

    Topics: Animals; Biomarkers, Tumor; Brain Neoplasms; Cell Line, Tumor; Dacarbazine; Drug Resistance, Neoplas

2015
Chip-based analysis of exosomal mRNA mediating drug resistance in glioblastoma.
    Nature communications, 2015, May-11, Volume: 6

    Topics: Animals; Biomarkers, Tumor; Brain Neoplasms; Cell Line, Tumor; Dacarbazine; Drug Resistance, Neoplas

2015
Chip-based analysis of exosomal mRNA mediating drug resistance in glioblastoma.
    Nature communications, 2015, May-11, Volume: 6

    Topics: Animals; Biomarkers, Tumor; Brain Neoplasms; Cell Line, Tumor; Dacarbazine; Drug Resistance, Neoplas

2015
miR-20a mediates temozolomide-resistance in glioblastoma cells via negatively regulating LRIG1 expression.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2015, Volume: 71

    Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Dacarbazine;

2015
miR-20a mediates temozolomide-resistance in glioblastoma cells via negatively regulating LRIG1 expression.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2015, Volume: 71

    Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Dacarbazine;

2015
miR-20a mediates temozolomide-resistance in glioblastoma cells via negatively regulating LRIG1 expression.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2015, Volume: 71

    Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Dacarbazine;

2015
Long-term Results of a Survey of Prolonged Adjuvant Treatment with Temozolomide in Patients with Glioblastoma (SV3 Study).
    Clinical oncology (Royal College of Radiologists (Great Britain)), 2015, Volume: 27, Issue:8

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Dacarbazine; Glioblastoma; He

2015
Long-term Results of a Survey of Prolonged Adjuvant Treatment with Temozolomide in Patients with Glioblastoma (SV3 Study).
    Clinical oncology (Royal College of Radiologists (Great Britain)), 2015, Volume: 27, Issue:8

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Dacarbazine; Glioblastoma; He

2015
Long-term Results of a Survey of Prolonged Adjuvant Treatment with Temozolomide in Patients with Glioblastoma (SV3 Study).
    Clinical oncology (Royal College of Radiologists (Great Britain)), 2015, Volume: 27, Issue:8

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Dacarbazine; Glioblastoma; He

2015
Survival benefit of levetiracetam in patients treated with concomitant chemoradiotherapy and adjuvant chemotherapy with temozolomide for glioblastoma multiforme.
    Cancer, 2015, Sep-01, Volume: 121, Issue:17

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Brain Ne

2015
Survival benefit of levetiracetam in patients treated with concomitant chemoradiotherapy and adjuvant chemotherapy with temozolomide for glioblastoma multiforme.
    Cancer, 2015, Sep-01, Volume: 121, Issue:17

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Brain Ne

2015
Survival benefit of levetiracetam in patients treated with concomitant chemoradiotherapy and adjuvant chemotherapy with temozolomide for glioblastoma multiforme.
    Cancer, 2015, Sep-01, Volume: 121, Issue:17

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Brain Ne

2015
Potentiation of temozolomide antitumor effect by purine receptor ligands able to restrain the in vitro growth of human glioblastoma stem cells.
    Purinergic signalling, 2015, Volume: 11, Issue:3

    Topics: Adenosine A3 Receptor Antagonists; Adenosine Triphosphate; Antineoplastic Agents, Alkylating; Apopto

2015
Potentiation of temozolomide antitumor effect by purine receptor ligands able to restrain the in vitro growth of human glioblastoma stem cells.
    Purinergic signalling, 2015, Volume: 11, Issue:3

    Topics: Adenosine A3 Receptor Antagonists; Adenosine Triphosphate; Antineoplastic Agents, Alkylating; Apopto

2015
Potentiation of temozolomide antitumor effect by purine receptor ligands able to restrain the in vitro growth of human glioblastoma stem cells.
    Purinergic signalling, 2015, Volume: 11, Issue:3

    Topics: Adenosine A3 Receptor Antagonists; Adenosine Triphosphate; Antineoplastic Agents, Alkylating; Apopto

2015
Temozolomide-loaded photopolymerizable PEG-DMA-based hydrogel for the treatment of glioblastoma.
    Journal of controlled release : official journal of the Controlled Release Society, 2015, Jul-28, Volume: 210

    Topics: Animals; Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cell Proli

2015
Temozolomide-loaded photopolymerizable PEG-DMA-based hydrogel for the treatment of glioblastoma.
    Journal of controlled release : official journal of the Controlled Release Society, 2015, Jul-28, Volume: 210

    Topics: Animals; Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cell Proli

2015
Temozolomide-loaded photopolymerizable PEG-DMA-based hydrogel for the treatment of glioblastoma.
    Journal of controlled release : official journal of the Controlled Release Society, 2015, Jul-28, Volume: 210

    Topics: Animals; Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cell Proli

2015
Upfront chemotherapy and subsequent resection for molecularly defined gliomas.
    Journal of neuro-oncology, 2015, Volume: 124, Issue:1

    Topics: Adult; Antineoplastic Agents; Brain Neoplasms; Chromosome Deletion; Chromosomes, Human, Pair 1; Daca

2015
Upfront chemotherapy and subsequent resection for molecularly defined gliomas.
    Journal of neuro-oncology, 2015, Volume: 124, Issue:1

    Topics: Adult; Antineoplastic Agents; Brain Neoplasms; Chromosome Deletion; Chromosomes, Human, Pair 1; Daca

2015
Upfront chemotherapy and subsequent resection for molecularly defined gliomas.
    Journal of neuro-oncology, 2015, Volume: 124, Issue:1

    Topics: Adult; Antineoplastic Agents; Brain Neoplasms; Chromosome Deletion; Chromosomes, Human, Pair 1; Daca

2015
Temozolomide induced bone marrow Suppression--A single institution outcome analysis and review of the literature.
    American journal of hematology, 2015, Volume: 90, Issue:9

    Topics: Adolescent; Adult; Aged; Anemia, Aplastic; Antineoplastic Agents, Alkylating; Astrocytoma; Bone Marr

2015
Temozolomide induced bone marrow Suppression--A single institution outcome analysis and review of the literature.
    American journal of hematology, 2015, Volume: 90, Issue:9

    Topics: Adolescent; Adult; Aged; Anemia, Aplastic; Antineoplastic Agents, Alkylating; Astrocytoma; Bone Marr

2015
Temozolomide induced bone marrow Suppression--A single institution outcome analysis and review of the literature.
    American journal of hematology, 2015, Volume: 90, Issue:9

    Topics: Adolescent; Adult; Aged; Anemia, Aplastic; Antineoplastic Agents, Alkylating; Astrocytoma; Bone Marr

2015
Impact of glycemia on survival of glioblastoma patients treated with radiation and temozolomide.
    Journal of neuro-oncology, 2015, Volume: 124, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Antineoplastic Agents, Hormonal; Brain Neoplasms; Dacarbazine; De

2015
Impact of glycemia on survival of glioblastoma patients treated with radiation and temozolomide.
    Journal of neuro-oncology, 2015, Volume: 124, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Antineoplastic Agents, Hormonal; Brain Neoplasms; Dacarbazine; De

2015
Impact of glycemia on survival of glioblastoma patients treated with radiation and temozolomide.
    Journal of neuro-oncology, 2015, Volume: 124, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Antineoplastic Agents, Hormonal; Brain Neoplasms; Dacarbazine; De

2015
A Model to Predict the Feasibility of Concurrent Chemoradiotherapy With Temozolomide in Glioblastoma Multiforme Patients Over Age 65.
    American journal of clinical oncology, 2017, Volume: 40, Issue:5

    Topics: Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Daca

2017
A Model to Predict the Feasibility of Concurrent Chemoradiotherapy With Temozolomide in Glioblastoma Multiforme Patients Over Age 65.
    American journal of clinical oncology, 2017, Volume: 40, Issue:5

    Topics: Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Daca

2017
A Model to Predict the Feasibility of Concurrent Chemoradiotherapy With Temozolomide in Glioblastoma Multiforme Patients Over Age 65.
    American journal of clinical oncology, 2017, Volume: 40, Issue:5

    Topics: Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Daca

2017
[Perampanel in the treatment of a patient with glioblastoma multiforme without IDH1 mutation and without MGMT promotor methylation].
    Fortschritte der Neurologie-Psychiatrie, 2015, Volume: 83, Issue:5

    Topics: Alkylating Agents; Brain Neoplasms; Dacarbazine; Epilepsies, Partial; Excitatory Amino Acid Antagoni

2015
[Perampanel in the treatment of a patient with glioblastoma multiforme without IDH1 mutation and without MGMT promotor methylation].
    Fortschritte der Neurologie-Psychiatrie, 2015, Volume: 83, Issue:5

    Topics: Alkylating Agents; Brain Neoplasms; Dacarbazine; Epilepsies, Partial; Excitatory Amino Acid Antagoni

2015
[Perampanel in the treatment of a patient with glioblastoma multiforme without IDH1 mutation and without MGMT promotor methylation].
    Fortschritte der Neurologie-Psychiatrie, 2015, Volume: 83, Issue:5

    Topics: Alkylating Agents; Brain Neoplasms; Dacarbazine; Epilepsies, Partial; Excitatory Amino Acid Antagoni

2015
Adjuvant temozolomide-based chemoradiotherapy versus radiotherapy alone in patients with WHO III astrocytoma: The Mainz experience.
    Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 2015, Volume: 191, Issue:8

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Astrocytoma; Brain Neoplasms; Chemoradi

2015
Adjuvant temozolomide-based chemoradiotherapy versus radiotherapy alone in patients with WHO III astrocytoma: The Mainz experience.
    Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 2015, Volume: 191, Issue:8

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Astrocytoma; Brain Neoplasms; Chemoradi

2015
Adjuvant temozolomide-based chemoradiotherapy versus radiotherapy alone in patients with WHO III astrocytoma: The Mainz experience.
    Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 2015, Volume: 191, Issue:8

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Astrocytoma; Brain Neoplasms; Chemoradi

2015
Clinical and Dosimetric Predictors of Acute Severe Lymphopenia During Radiation Therapy and Concurrent Temozolomide for High-Grade Glioma.
    International journal of radiation oncology, biology, physics, 2015, Aug-01, Volume: 92, Issue:5

    Topics: Acute Disease; Adult; Age Factors; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain

2015
Clinical and Dosimetric Predictors of Acute Severe Lymphopenia During Radiation Therapy and Concurrent Temozolomide for High-Grade Glioma.
    International journal of radiation oncology, biology, physics, 2015, Aug-01, Volume: 92, Issue:5

    Topics: Acute Disease; Adult; Age Factors; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain

2015
Clinical and Dosimetric Predictors of Acute Severe Lymphopenia During Radiation Therapy and Concurrent Temozolomide for High-Grade Glioma.
    International journal of radiation oncology, biology, physics, 2015, Aug-01, Volume: 92, Issue:5

    Topics: Acute Disease; Adult; Age Factors; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain

2015
Down regulation of Akirin-2 increases chemosensitivity in human glioblastomas more efficiently than Twist-1.
    Oncotarget, 2015, Aug-28, Volume: 6, Issue:25

    Topics: Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Caspase 3; Caspase 7; CD11b Antigen;

2015
Down regulation of Akirin-2 increases chemosensitivity in human glioblastomas more efficiently than Twist-1.
    Oncotarget, 2015, Aug-28, Volume: 6, Issue:25

    Topics: Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Caspase 3; Caspase 7; CD11b Antigen;

2015
Down regulation of Akirin-2 increases chemosensitivity in human glioblastomas more efficiently than Twist-1.
    Oncotarget, 2015, Aug-28, Volume: 6, Issue:25

    Topics: Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Caspase 3; Caspase 7; CD11b Antigen;

2015
Impact of oligodendroglial component in glioblastoma (GBM-O): Is the outcome favourable than glioblastoma?
    Clinical neurology and neurosurgery, 2015, Volume: 135

    Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Ne

2015
Impact of oligodendroglial component in glioblastoma (GBM-O): Is the outcome favourable than glioblastoma?
    Clinical neurology and neurosurgery, 2015, Volume: 135

    Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Ne

2015
Impact of oligodendroglial component in glioblastoma (GBM-O): Is the outcome favourable than glioblastoma?
    Clinical neurology and neurosurgery, 2015, Volume: 135

    Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Ne

2015
Metronomic chemotherapy with daily low-dose temozolomide and celecoxib in elderly patients with newly diagnosed glioblastoma multiforme: a retrospective analysis.
    Journal of neuro-oncology, 2015, Volume: 124, Issue:2

    Topics: Aged; Aged, 80 and over; Antineoplastic Agents; Brain Neoplasms; Celecoxib; Chemoradiotherapy; Comor

2015
Metronomic chemotherapy with daily low-dose temozolomide and celecoxib in elderly patients with newly diagnosed glioblastoma multiforme: a retrospective analysis.
    Journal of neuro-oncology, 2015, Volume: 124, Issue:2

    Topics: Aged; Aged, 80 and over; Antineoplastic Agents; Brain Neoplasms; Celecoxib; Chemoradiotherapy; Comor

2015
Metronomic chemotherapy with daily low-dose temozolomide and celecoxib in elderly patients with newly diagnosed glioblastoma multiforme: a retrospective analysis.
    Journal of neuro-oncology, 2015, Volume: 124, Issue:2

    Topics: Aged; Aged, 80 and over; Antineoplastic Agents; Brain Neoplasms; Celecoxib; Chemoradiotherapy; Comor

2015
Orthogonal targeting of EGFRvIII expressing glioblastomas through simultaneous EGFR and PLK1 inhibition.
    Oncotarget, 2015, May-20, Volume: 6, Issue:14

    Topics: Animals; Antineoplastic Agents, Alkylating; Blotting, Western; Brain Neoplasms; Cell Cycle Proteins;

2015
Orthogonal targeting of EGFRvIII expressing glioblastomas through simultaneous EGFR and PLK1 inhibition.
    Oncotarget, 2015, May-20, Volume: 6, Issue:14

    Topics: Animals; Antineoplastic Agents, Alkylating; Blotting, Western; Brain Neoplasms; Cell Cycle Proteins;

2015
Orthogonal targeting of EGFRvIII expressing glioblastomas through simultaneous EGFR and PLK1 inhibition.
    Oncotarget, 2015, May-20, Volume: 6, Issue:14

    Topics: Animals; Antineoplastic Agents, Alkylating; Blotting, Western; Brain Neoplasms; Cell Cycle Proteins;

2015
[A pleural transudate with a 0 g/L protein level].
    Revue des maladies respiratoires, 2015, Volume: 32, Issue:5

    Topics: Analgesics; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Brain Neoplasms; Catheters,

2015
[A pleural transudate with a 0 g/L protein level].
    Revue des maladies respiratoires, 2015, Volume: 32, Issue:5

    Topics: Analgesics; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Brain Neoplasms; Catheters,

2015
[A pleural transudate with a 0 g/L protein level].
    Revue des maladies respiratoires, 2015, Volume: 32, Issue:5

    Topics: Analgesics; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Brain Neoplasms; Catheters,

2015
Photodynamic therapy in the treatment of brain tumours. A feasibility study.
    Photodiagnosis and photodynamic therapy, 2015, Volume: 12, Issue:3

    Topics: Adolescent; Adult; Aged; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Dihematoporphyrin

2015
Photodynamic therapy in the treatment of brain tumours. A feasibility study.
    Photodiagnosis and photodynamic therapy, 2015, Volume: 12, Issue:3

    Topics: Adolescent; Adult; Aged; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Dihematoporphyrin

2015
Photodynamic therapy in the treatment of brain tumours. A feasibility study.
    Photodiagnosis and photodynamic therapy, 2015, Volume: 12, Issue:3

    Topics: Adolescent; Adult; Aged; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Dihematoporphyrin

2015
Brain Stem and Entire Spinal Leptomeningeal Dissemination of Supratentorial Glioblastoma Multiforme in a Patient during Postoperative Radiochemotherapy: Case Report and Review of the Literatures.
    Medicine, 2015, Volume: 94, Issue:24

    Topics: Adult; Antineoplastic Agents; Brain Neoplasms; Brain Stem Neoplasms; Chemoradiotherapy; Cisplatin; D

2015
Brain Stem and Entire Spinal Leptomeningeal Dissemination of Supratentorial Glioblastoma Multiforme in a Patient during Postoperative Radiochemotherapy: Case Report and Review of the Literatures.
    Medicine, 2015, Volume: 94, Issue:24

    Topics: Adult; Antineoplastic Agents; Brain Neoplasms; Brain Stem Neoplasms; Chemoradiotherapy; Cisplatin; D

2015
Brain Stem and Entire Spinal Leptomeningeal Dissemination of Supratentorial Glioblastoma Multiforme in a Patient during Postoperative Radiochemotherapy: Case Report and Review of the Literatures.
    Medicine, 2015, Volume: 94, Issue:24

    Topics: Adult; Antineoplastic Agents; Brain Neoplasms; Brain Stem Neoplasms; Chemoradiotherapy; Cisplatin; D

2015
Hypercellularity Components of Glioblastoma Identified by High b-Value Diffusion-Weighted Imaging.
    International journal of radiation oncology, biology, physics, 2015, Jul-15, Volume: 92, Issue:4

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Edema; Brain Neoplasms; Chemoradiotherapy; Dac

2015
Hypercellularity Components of Glioblastoma Identified by High b-Value Diffusion-Weighted Imaging.
    International journal of radiation oncology, biology, physics, 2015, Jul-15, Volume: 92, Issue:4

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Edema; Brain Neoplasms; Chemoradiotherapy; Dac

2015
Hypercellularity Components of Glioblastoma Identified by High b-Value Diffusion-Weighted Imaging.
    International journal of radiation oncology, biology, physics, 2015, Jul-15, Volume: 92, Issue:4

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Edema; Brain Neoplasms; Chemoradiotherapy; Dac

2015
The Synergistic Effect of Combination Progesterone and Temozolomide on Human Glioblastoma Cells.
    PloS one, 2015, Volume: 10, Issue:6

    Topics: Anti-Inflammatory Agents; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Pr

2015
The Synergistic Effect of Combination Progesterone and Temozolomide on Human Glioblastoma Cells.
    PloS one, 2015, Volume: 10, Issue:6

    Topics: Anti-Inflammatory Agents; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Pr

2015
The Synergistic Effect of Combination Progesterone and Temozolomide on Human Glioblastoma Cells.
    PloS one, 2015, Volume: 10, Issue:6

    Topics: Anti-Inflammatory Agents; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Pr

2015
Digital PCR quantification of MGMT methylation refines prediction of clinical benefit from alkylating agents in glioblastoma and metastatic colorectal cancer.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2015, Volume: 26, Issue:9

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Colorectal Neoplasms; Dacarbazine; Disease-Free

2015
Digital PCR quantification of MGMT methylation refines prediction of clinical benefit from alkylating agents in glioblastoma and metastatic colorectal cancer.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2015, Volume: 26, Issue:9

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Colorectal Neoplasms; Dacarbazine; Disease-Free

2015
Digital PCR quantification of MGMT methylation refines prediction of clinical benefit from alkylating agents in glioblastoma and metastatic colorectal cancer.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2015, Volume: 26, Issue:9

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Colorectal Neoplasms; Dacarbazine; Disease-Free

2015
Digital PCR quantification of MGMT methylation refines prediction of clinical benefit from alkylating agents in glioblastoma and metastatic colorectal cancer.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2015, Volume: 26, Issue:9

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Colorectal Neoplasms; Dacarbazine; Disease-Free

2015
Digital PCR quantification of MGMT methylation refines prediction of clinical benefit from alkylating agents in glioblastoma and metastatic colorectal cancer.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2015, Volume: 26, Issue:9

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Colorectal Neoplasms; Dacarbazine; Disease-Free

2015
Digital PCR quantification of MGMT methylation refines prediction of clinical benefit from alkylating agents in glioblastoma and metastatic colorectal cancer.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2015, Volume: 26, Issue:9

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Colorectal Neoplasms; Dacarbazine; Disease-Free

2015
Digital PCR quantification of MGMT methylation refines prediction of clinical benefit from alkylating agents in glioblastoma and metastatic colorectal cancer.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2015, Volume: 26, Issue:9

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Colorectal Neoplasms; Dacarbazine; Disease-Free

2015
Digital PCR quantification of MGMT methylation refines prediction of clinical benefit from alkylating agents in glioblastoma and metastatic colorectal cancer.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2015, Volume: 26, Issue:9

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Colorectal Neoplasms; Dacarbazine; Disease-Free

2015
Digital PCR quantification of MGMT methylation refines prediction of clinical benefit from alkylating agents in glioblastoma and metastatic colorectal cancer.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2015, Volume: 26, Issue:9

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Colorectal Neoplasms; Dacarbazine; Disease-Free

2015
Digital PCR quantification of MGMT methylation refines prediction of clinical benefit from alkylating agents in glioblastoma and metastatic colorectal cancer.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2015, Volume: 26, Issue:9

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Colorectal Neoplasms; Dacarbazine; Disease-Free

2015
Digital PCR quantification of MGMT methylation refines prediction of clinical benefit from alkylating agents in glioblastoma and metastatic colorectal cancer.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2015, Volume: 26, Issue:9

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Colorectal Neoplasms; Dacarbazine; Disease-Free

2015
Digital PCR quantification of MGMT methylation refines prediction of clinical benefit from alkylating agents in glioblastoma and metastatic colorectal cancer.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2015, Volume: 26, Issue:9

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Colorectal Neoplasms; Dacarbazine; Disease-Free

2015
Digital PCR quantification of MGMT methylation refines prediction of clinical benefit from alkylating agents in glioblastoma and metastatic colorectal cancer.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2015, Volume: 26, Issue:9

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Colorectal Neoplasms; Dacarbazine; Disease-Free

2015
Digital PCR quantification of MGMT methylation refines prediction of clinical benefit from alkylating agents in glioblastoma and metastatic colorectal cancer.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2015, Volume: 26, Issue:9

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Colorectal Neoplasms; Dacarbazine; Disease-Free

2015
Digital PCR quantification of MGMT methylation refines prediction of clinical benefit from alkylating agents in glioblastoma and metastatic colorectal cancer.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2015, Volume: 26, Issue:9

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Colorectal Neoplasms; Dacarbazine; Disease-Free

2015
Digital PCR quantification of MGMT methylation refines prediction of clinical benefit from alkylating agents in glioblastoma and metastatic colorectal cancer.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2015, Volume: 26, Issue:9

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Colorectal Neoplasms; Dacarbazine; Disease-Free

2015
Digital PCR quantification of MGMT methylation refines prediction of clinical benefit from alkylating agents in glioblastoma and metastatic colorectal cancer.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2015, Volume: 26, Issue:9

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Colorectal Neoplasms; Dacarbazine; Disease-Free

2015
Digital PCR quantification of MGMT methylation refines prediction of clinical benefit from alkylating agents in glioblastoma and metastatic colorectal cancer.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2015, Volume: 26, Issue:9

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Colorectal Neoplasms; Dacarbazine; Disease-Free

2015
Digital PCR quantification of MGMT methylation refines prediction of clinical benefit from alkylating agents in glioblastoma and metastatic colorectal cancer.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2015, Volume: 26, Issue:9

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Colorectal Neoplasms; Dacarbazine; Disease-Free

2015
Digital PCR quantification of MGMT methylation refines prediction of clinical benefit from alkylating agents in glioblastoma and metastatic colorectal cancer.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2015, Volume: 26, Issue:9

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Colorectal Neoplasms; Dacarbazine; Disease-Free

2015
Digital PCR quantification of MGMT methylation refines prediction of clinical benefit from alkylating agents in glioblastoma and metastatic colorectal cancer.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2015, Volume: 26, Issue:9

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Colorectal Neoplasms; Dacarbazine; Disease-Free

2015
Digital PCR quantification of MGMT methylation refines prediction of clinical benefit from alkylating agents in glioblastoma and metastatic colorectal cancer.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2015, Volume: 26, Issue:9

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Colorectal Neoplasms; Dacarbazine; Disease-Free

2015
Digital PCR quantification of MGMT methylation refines prediction of clinical benefit from alkylating agents in glioblastoma and metastatic colorectal cancer.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2015, Volume: 26, Issue:9

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Colorectal Neoplasms; Dacarbazine; Disease-Free

2015
Digital PCR quantification of MGMT methylation refines prediction of clinical benefit from alkylating agents in glioblastoma and metastatic colorectal cancer.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2015, Volume: 26, Issue:9

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Colorectal Neoplasms; Dacarbazine; Disease-Free

2015
Digital PCR quantification of MGMT methylation refines prediction of clinical benefit from alkylating agents in glioblastoma and metastatic colorectal cancer.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2015, Volume: 26, Issue:9

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Colorectal Neoplasms; Dacarbazine; Disease-Free

2015
Digital PCR quantification of MGMT methylation refines prediction of clinical benefit from alkylating agents in glioblastoma and metastatic colorectal cancer.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2015, Volume: 26, Issue:9

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Colorectal Neoplasms; Dacarbazine; Disease-Free

2015
Digital PCR quantification of MGMT methylation refines prediction of clinical benefit from alkylating agents in glioblastoma and metastatic colorectal cancer.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2015, Volume: 26, Issue:9

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Colorectal Neoplasms; Dacarbazine; Disease-Free

2015
Management of glioblastoma in Victoria, Australia (2006-2008).
    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2015, Volume: 22, Issue:9

    Topics: Aged; Antineoplastic Agents; Brain Neoplasms; Chemoradiotherapy; Cohort Studies; Dacarbazine; Female

2015
Management of glioblastoma in Victoria, Australia (2006-2008).
    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2015, Volume: 22, Issue:9

    Topics: Aged; Antineoplastic Agents; Brain Neoplasms; Chemoradiotherapy; Cohort Studies; Dacarbazine; Female

2015
Management of glioblastoma in Victoria, Australia (2006-2008).
    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2015, Volume: 22, Issue:9

    Topics: Aged; Antineoplastic Agents; Brain Neoplasms; Chemoradiotherapy; Cohort Studies; Dacarbazine; Female

2015
A Potential Role for the Inhibition of PI3K Signaling in Glioblastoma Therapy.
    PloS one, 2015, Volume: 10, Issue:6

    Topics: Antineoplastic Agents; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cell Movement; Cell Proliferati

2015
A Potential Role for the Inhibition of PI3K Signaling in Glioblastoma Therapy.
    PloS one, 2015, Volume: 10, Issue:6

    Topics: Antineoplastic Agents; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cell Movement; Cell Proliferati

2015
A Potential Role for the Inhibition of PI3K Signaling in Glioblastoma Therapy.
    PloS one, 2015, Volume: 10, Issue:6

    Topics: Antineoplastic Agents; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cell Movement; Cell Proliferati

2015
Patients With Proneural Glioblastoma May Derive Overall Survival Benefit From the Addition of Bevacizumab to First-Line Radiotherapy and Temozolomide: Retrospective Analysis of the AVAglio Trial.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2015, Sep-01, Volume: 33, Issue:25

    Topics: Adult; Aged; Angiogenesis Inhibitors; Antineoplastic Agents, Alkylating; Bevacizumab; Brain Neoplasm

2015
Patients With Proneural Glioblastoma May Derive Overall Survival Benefit From the Addition of Bevacizumab to First-Line Radiotherapy and Temozolomide: Retrospective Analysis of the AVAglio Trial.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2015, Sep-01, Volume: 33, Issue:25

    Topics: Adult; Aged; Angiogenesis Inhibitors; Antineoplastic Agents, Alkylating; Bevacizumab; Brain Neoplasm

2015
Patients With Proneural Glioblastoma May Derive Overall Survival Benefit From the Addition of Bevacizumab to First-Line Radiotherapy and Temozolomide: Retrospective Analysis of the AVAglio Trial.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2015, Sep-01, Volume: 33, Issue:25

    Topics: Adult; Aged; Angiogenesis Inhibitors; Antineoplastic Agents, Alkylating; Bevacizumab; Brain Neoplasm

2015
Brain Exposure of Two Selective Dual CDK4 and CDK6 Inhibitors and the Antitumor Activity of CDK4 and CDK6 Inhibition in Combination with Temozolomide in an Intracranial Glioblastoma Xenograft.
    Drug metabolism and disposition: the biological fate of chemicals, 2015, Volume: 43, Issue:9

    Topics: Aminopyridines; Animals; Antineoplastic Combined Chemotherapy Protocols; Benzimidazoles; Brain; Brai

2015
Brain Exposure of Two Selective Dual CDK4 and CDK6 Inhibitors and the Antitumor Activity of CDK4 and CDK6 Inhibition in Combination with Temozolomide in an Intracranial Glioblastoma Xenograft.
    Drug metabolism and disposition: the biological fate of chemicals, 2015, Volume: 43, Issue:9

    Topics: Aminopyridines; Animals; Antineoplastic Combined Chemotherapy Protocols; Benzimidazoles; Brain; Brai

2015
Brain Exposure of Two Selective Dual CDK4 and CDK6 Inhibitors and the Antitumor Activity of CDK4 and CDK6 Inhibition in Combination with Temozolomide in an Intracranial Glioblastoma Xenograft.
    Drug metabolism and disposition: the biological fate of chemicals, 2015, Volume: 43, Issue:9

    Topics: Aminopyridines; Animals; Antineoplastic Combined Chemotherapy Protocols; Benzimidazoles; Brain; Brai

2015
An image guided small animal radiation therapy platform (SmART) to monitor glioblastoma progression and therapy response.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2015, Volume: 116, Issue:3

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Chemoradiotherapy; Co

2015
An image guided small animal radiation therapy platform (SmART) to monitor glioblastoma progression and therapy response.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2015, Volume: 116, Issue:3

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Chemoradiotherapy; Co

2015
An image guided small animal radiation therapy platform (SmART) to monitor glioblastoma progression and therapy response.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2015, Volume: 116, Issue:3

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Chemoradiotherapy; Co

2015
[Exceptional metastasis of glioblastoma].
    The Pan African medical journal, 2015, Volume: 20

    Topics: Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Gl

2015
[Exceptional metastasis of glioblastoma].
    The Pan African medical journal, 2015, Volume: 20

    Topics: Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Gl

2015
[Exceptional metastasis of glioblastoma].
    The Pan African medical journal, 2015, Volume: 20

    Topics: Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Gl

2015
A new anti-glioma therapy, AG119: pre-clinical assessment in a mouse GL261 glioma model.
    BMC cancer, 2015, Jul-17, Volume: 15

    Topics: Angiogenesis Inhibitors; Animals; Brain Neoplasms; Cell Line, Tumor; Dacarbazine; Disease Models, An

2015
A new anti-glioma therapy, AG119: pre-clinical assessment in a mouse GL261 glioma model.
    BMC cancer, 2015, Jul-17, Volume: 15

    Topics: Angiogenesis Inhibitors; Animals; Brain Neoplasms; Cell Line, Tumor; Dacarbazine; Disease Models, An

2015
A new anti-glioma therapy, AG119: pre-clinical assessment in a mouse GL261 glioma model.
    BMC cancer, 2015, Jul-17, Volume: 15

    Topics: Angiogenesis Inhibitors; Animals; Brain Neoplasms; Cell Line, Tumor; Dacarbazine; Disease Models, An

2015
NVP-BEZ235, a novel dual PI3K-mTOR inhibitor displays anti-glioma activity and reduces chemoresistance to temozolomide in human glioma cells.
    Cancer letters, 2015, Oct-10, Volume: 367, Issue:1

    Topics: Animals; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Apoptosi

2015
NVP-BEZ235, a novel dual PI3K-mTOR inhibitor displays anti-glioma activity and reduces chemoresistance to temozolomide in human glioma cells.
    Cancer letters, 2015, Oct-10, Volume: 367, Issue:1

    Topics: Animals; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Apoptosi

2015
NVP-BEZ235, a novel dual PI3K-mTOR inhibitor displays anti-glioma activity and reduces chemoresistance to temozolomide in human glioma cells.
    Cancer letters, 2015, Oct-10, Volume: 367, Issue:1

    Topics: Animals; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Apoptosi

2015
Liposome encapsulated of temozolomide for the treatment of glioma tumor: preparation, characterization and evaluation.
    Drug discoveries & therapeutics, 2015, Volume: 9, Issue:3

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Female; Glioma; Liposomes;

2015
Liposome encapsulated of temozolomide for the treatment of glioma tumor: preparation, characterization and evaluation.
    Drug discoveries & therapeutics, 2015, Volume: 9, Issue:3

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Female; Glioma; Liposomes;

2015
Liposome encapsulated of temozolomide for the treatment of glioma tumor: preparation, characterization and evaluation.
    Drug discoveries & therapeutics, 2015, Volume: 9, Issue:3

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Female; Glioma; Liposomes;

2015
Novel RGD containing, temozolomide-loading nanostructured lipid carriers for glioblastoma multiforme chemotherapy.
    Drug delivery, 2016, Volume: 23, Issue:4

    Topics: Animals; Brain Neoplasms; Cell Line, Tumor; Dacarbazine; Drug Carriers; Drug Liberation; Glioblastom

2016
Novel RGD containing, temozolomide-loading nanostructured lipid carriers for glioblastoma multiforme chemotherapy.
    Drug delivery, 2016, Volume: 23, Issue:4

    Topics: Animals; Brain Neoplasms; Cell Line, Tumor; Dacarbazine; Drug Carriers; Drug Liberation; Glioblastom

2016
Novel RGD containing, temozolomide-loading nanostructured lipid carriers for glioblastoma multiforme chemotherapy.
    Drug delivery, 2016, Volume: 23, Issue:4

    Topics: Animals; Brain Neoplasms; Cell Line, Tumor; Dacarbazine; Drug Carriers; Drug Liberation; Glioblastom

2016
Temozolomide competes for P-glycoprotein and contributes to chemoresistance in glioblastoma cells.
    Cancer letters, 2015, Oct-10, Volume: 367, Issue:1

    Topics: Animals; Antineoplastic Agents, Alkylating; ATP Binding Cassette Transporter, Subfamily B; Binding,

2015
Temozolomide competes for P-glycoprotein and contributes to chemoresistance in glioblastoma cells.
    Cancer letters, 2015, Oct-10, Volume: 367, Issue:1

    Topics: Animals; Antineoplastic Agents, Alkylating; ATP Binding Cassette Transporter, Subfamily B; Binding,

2015
Temozolomide competes for P-glycoprotein and contributes to chemoresistance in glioblastoma cells.
    Cancer letters, 2015, Oct-10, Volume: 367, Issue:1

    Topics: Animals; Antineoplastic Agents, Alkylating; ATP Binding Cassette Transporter, Subfamily B; Binding,

2015
Microenvironmental Modulation of Decorin and Lumican in Temozolomide-Resistant Glioblastoma and Neuroblastoma Cancer Stem-Like Cells.
    PloS one, 2015, Volume: 10, Issue:7

    Topics: Brain Neoplasms; Chondroitin Sulfate Proteoglycans; Dacarbazine; Decorin; Glioblastoma; Humans; Kera

2015
Microenvironmental Modulation of Decorin and Lumican in Temozolomide-Resistant Glioblastoma and Neuroblastoma Cancer Stem-Like Cells.
    PloS one, 2015, Volume: 10, Issue:7

    Topics: Brain Neoplasms; Chondroitin Sulfate Proteoglycans; Dacarbazine; Decorin; Glioblastoma; Humans; Kera

2015
Microenvironmental Modulation of Decorin and Lumican in Temozolomide-Resistant Glioblastoma and Neuroblastoma Cancer Stem-Like Cells.
    PloS one, 2015, Volume: 10, Issue:7

    Topics: Brain Neoplasms; Chondroitin Sulfate Proteoglycans; Dacarbazine; Decorin; Glioblastoma; Humans; Kera

2015
Induction of microRNA-146a is involved in curcumin-mediated enhancement of temozolomide cytotoxicity against human glioblastoma.
    Molecular medicine reports, 2015, Volume: 12, Issue:4

    Topics: Antineoplastic Agents; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Curcumin; D

2015
Induction of microRNA-146a is involved in curcumin-mediated enhancement of temozolomide cytotoxicity against human glioblastoma.
    Molecular medicine reports, 2015, Volume: 12, Issue:4

    Topics: Antineoplastic Agents; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Curcumin; D

2015
Induction of microRNA-146a is involved in curcumin-mediated enhancement of temozolomide cytotoxicity against human glioblastoma.
    Molecular medicine reports, 2015, Volume: 12, Issue:4

    Topics: Antineoplastic Agents; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Curcumin; D

2015
MGMT inactivation and clinical response in newly diagnosed GBM patients treated with Gliadel.
    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2015, Volume: 22, Issue:12

    Topics: Aged; Aged, 80 and over; Brain Neoplasms; Carmustine; Chemoradiotherapy; Dacarbazine; Decanoic Acids

2015
MGMT inactivation and clinical response in newly diagnosed GBM patients treated with Gliadel.
    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2015, Volume: 22, Issue:12

    Topics: Aged; Aged, 80 and over; Brain Neoplasms; Carmustine; Chemoradiotherapy; Dacarbazine; Decanoic Acids

2015
MGMT inactivation and clinical response in newly diagnosed GBM patients treated with Gliadel.
    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2015, Volume: 22, Issue:12

    Topics: Aged; Aged, 80 and over; Brain Neoplasms; Carmustine; Chemoradiotherapy; Dacarbazine; Decanoic Acids

2015
miR-144-3p exerts anti-tumor effects in glioblastoma by targeting c-Met.
    Journal of neurochemistry, 2015, Volume: 135, Issue:2

    Topics: 3' Untranslated Regions; Animals; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Apoptosi

2015
miR-144-3p exerts anti-tumor effects in glioblastoma by targeting c-Met.
    Journal of neurochemistry, 2015, Volume: 135, Issue:2

    Topics: 3' Untranslated Regions; Animals; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Apoptosi

2015
miR-144-3p exerts anti-tumor effects in glioblastoma by targeting c-Met.
    Journal of neurochemistry, 2015, Volume: 135, Issue:2

    Topics: 3' Untranslated Regions; Animals; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Apoptosi

2015
Dynamic contrast enhanced T1 MRI perfusion differentiates pseudoprogression from recurrent glioblastoma.
    Journal of neuro-oncology, 2015, Volume: 125, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Alkaloids; Antineoplastic Agents, Alkylating; Brain Neoplasms; Contr

2015
Dynamic contrast enhanced T1 MRI perfusion differentiates pseudoprogression from recurrent glioblastoma.
    Journal of neuro-oncology, 2015, Volume: 125, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Alkaloids; Antineoplastic Agents, Alkylating; Brain Neoplasms; Contr

2015
Dynamic contrast enhanced T1 MRI perfusion differentiates pseudoprogression from recurrent glioblastoma.
    Journal of neuro-oncology, 2015, Volume: 125, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Alkaloids; Antineoplastic Agents, Alkylating; Brain Neoplasms; Contr

2015
Independent Poor Prognostic Factors for True Progression after Radiation Therapy and Concomitant Temozolomide in Patients with Glioblastoma: Subependymal Enhancement and Low ADC Value.
    AJNR. American journal of neuroradiology, 2015, Volume: 36, Issue:10

    Topics: Adult; Aged; Aged, 80 and over; Brain Neoplasms; Chemoradiotherapy; Cranial Irradiation; Dacarbazine

2015
Independent Poor Prognostic Factors for True Progression after Radiation Therapy and Concomitant Temozolomide in Patients with Glioblastoma: Subependymal Enhancement and Low ADC Value.
    AJNR. American journal of neuroradiology, 2015, Volume: 36, Issue:10

    Topics: Adult; Aged; Aged, 80 and over; Brain Neoplasms; Chemoradiotherapy; Cranial Irradiation; Dacarbazine

2015
Independent Poor Prognostic Factors for True Progression after Radiation Therapy and Concomitant Temozolomide in Patients with Glioblastoma: Subependymal Enhancement and Low ADC Value.
    AJNR. American journal of neuroradiology, 2015, Volume: 36, Issue:10

    Topics: Adult; Aged; Aged, 80 and over; Brain Neoplasms; Chemoradiotherapy; Cranial Irradiation; Dacarbazine

2015
Temozolomide Treatment for Pediatric Refractory Anaplastic Ependymoma with Low MGMT Protein Expression.
    Pediatric blood & cancer, 2016, Volume: 63, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Child, Preschool; Dacarbazine; DNA Modification

2016
Temozolomide Treatment for Pediatric Refractory Anaplastic Ependymoma with Low MGMT Protein Expression.
    Pediatric blood & cancer, 2016, Volume: 63, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Child, Preschool; Dacarbazine; DNA Modification

2016
Temozolomide Treatment for Pediatric Refractory Anaplastic Ependymoma with Low MGMT Protein Expression.
    Pediatric blood & cancer, 2016, Volume: 63, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Child, Preschool; Dacarbazine; DNA Modification

2016
A New Epigenetic Mechanism of Temozolomide Action in Glioma Cells.
    PloS one, 2015, Volume: 10, Issue:8

    Topics: 5-Methylcytosine; Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Dac

2015
A New Epigenetic Mechanism of Temozolomide Action in Glioma Cells.
    PloS one, 2015, Volume: 10, Issue:8

    Topics: 5-Methylcytosine; Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Dac

2015
A New Epigenetic Mechanism of Temozolomide Action in Glioma Cells.
    PloS one, 2015, Volume: 10, Issue:8

    Topics: 5-Methylcytosine; Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Dac

2015
Diagnosis and Management of Spinal Metastasis of Glioblastoma.
    The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques, 2015, Volume: 42, Issue:6

    Topics: Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Brai

2015
Diagnosis and Management of Spinal Metastasis of Glioblastoma.
    The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques, 2015, Volume: 42, Issue:6

    Topics: Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Brai

2015
Diagnosis and Management of Spinal Metastasis of Glioblastoma.
    The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques, 2015, Volume: 42, Issue:6

    Topics: Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Brai

2015
Investigating a signature of temozolomide resistance in GBM cell lines using metabolomics.
    Journal of neuro-oncology, 2015, Volume: 125, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms;

2015
Investigating a signature of temozolomide resistance in GBM cell lines using metabolomics.
    Journal of neuro-oncology, 2015, Volume: 125, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms;

2015
Investigating a signature of temozolomide resistance in GBM cell lines using metabolomics.
    Journal of neuro-oncology, 2015, Volume: 125, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms;

2015
Temozolomide as salvage treatment for recurrent intracranial ependymomas of the adult: a retrospective study.
    Neuro-oncology, 2016, Volume: 18, Issue:2

    Topics: Adolescent; Adult; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Ependymoma; Fema

2016
Temozolomide as salvage treatment for recurrent intracranial ependymomas of the adult: a retrospective study.
    Neuro-oncology, 2016, Volume: 18, Issue:2

    Topics: Adolescent; Adult; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Ependymoma; Fema

2016
Temozolomide as salvage treatment for recurrent intracranial ependymomas of the adult: a retrospective study.
    Neuro-oncology, 2016, Volume: 18, Issue:2

    Topics: Adolescent; Adult; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Ependymoma; Fema

2016
Encapsulation of temozolomide in a tumor-targeting nanocomplex enhances anti-cancer efficacy and reduces toxicity in a mouse model of glioblastoma.
    Cancer letters, 2015, Dec-01, Volume: 369, Issue:1

    Topics: Animals; Antineoplastic Agents; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cell Survival; Dacarba

2015
Encapsulation of temozolomide in a tumor-targeting nanocomplex enhances anti-cancer efficacy and reduces toxicity in a mouse model of glioblastoma.
    Cancer letters, 2015, Dec-01, Volume: 369, Issue:1

    Topics: Animals; Antineoplastic Agents; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cell Survival; Dacarba

2015
Encapsulation of temozolomide in a tumor-targeting nanocomplex enhances anti-cancer efficacy and reduces toxicity in a mouse model of glioblastoma.
    Cancer letters, 2015, Dec-01, Volume: 369, Issue:1

    Topics: Animals; Antineoplastic Agents; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cell Survival; Dacarba

2015
BC3EE2,9B, a synthetic carbazole derivative, upregulates autophagy and synergistically sensitizes human GBM8901 glioblastoma cells to temozolomide.
    International journal of molecular medicine, 2015, Volume: 36, Issue:5

    Topics: Antineoplastic Agents; Autophagy; Brain Neoplasms; Carbazoles; Cell Cycle Checkpoints; Cell Line, Tu

2015
BC3EE2,9B, a synthetic carbazole derivative, upregulates autophagy and synergistically sensitizes human GBM8901 glioblastoma cells to temozolomide.
    International journal of molecular medicine, 2015, Volume: 36, Issue:5

    Topics: Antineoplastic Agents; Autophagy; Brain Neoplasms; Carbazoles; Cell Cycle Checkpoints; Cell Line, Tu

2015
BC3EE2,9B, a synthetic carbazole derivative, upregulates autophagy and synergistically sensitizes human GBM8901 glioblastoma cells to temozolomide.
    International journal of molecular medicine, 2015, Volume: 36, Issue:5

    Topics: Antineoplastic Agents; Autophagy; Brain Neoplasms; Carbazoles; Cell Cycle Checkpoints; Cell Line, Tu

2015
Metformin influences progression in diabetic glioblastoma patients.
    Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 2015, Volume: 191, Issue:12

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Blood Glucose; Brain;

2015
Metformin influences progression in diabetic glioblastoma patients.
    Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 2015, Volume: 191, Issue:12

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Blood Glucose; Brain;

2015
Metformin influences progression in diabetic glioblastoma patients.
    Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 2015, Volume: 191, Issue:12

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Blood Glucose; Brain;

2015
Interferon-α/β enhances temozolomide activity against MGMT-positive glioma stem-like cells.
    Oncology reports, 2015, Volume: 34, Issue:5

    Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Cel

2015
Interferon-α/β enhances temozolomide activity against MGMT-positive glioma stem-like cells.
    Oncology reports, 2015, Volume: 34, Issue:5

    Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Cel

2015
Interferon-α/β enhances temozolomide activity against MGMT-positive glioma stem-like cells.
    Oncology reports, 2015, Volume: 34, Issue:5

    Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Cel

2015
Inhibition of DNA-repair genes Ercc1 and Mgmt enhances temozolomide efficacy in gliomas treatment: a pre-clinical study.
    Oncotarget, 2015, Oct-06, Volume: 6, Issue:30

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Death; Cell Line, Tumor; Cell Prol

2015
Inhibition of DNA-repair genes Ercc1 and Mgmt enhances temozolomide efficacy in gliomas treatment: a pre-clinical study.
    Oncotarget, 2015, Oct-06, Volume: 6, Issue:30

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Death; Cell Line, Tumor; Cell Prol

2015
Inhibition of DNA-repair genes Ercc1 and Mgmt enhances temozolomide efficacy in gliomas treatment: a pre-clinical study.
    Oncotarget, 2015, Oct-06, Volume: 6, Issue:30

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Death; Cell Line, Tumor; Cell Prol

2015
DNMT1 mediates chemosensitivity by reducing methylation of miRNA-20a promoter in glioma cells.
    Experimental & molecular medicine, 2015, Sep-04, Volume: 47

    Topics: Animals; Antineoplastic Agents, Alkylating; Apoptosis; Brain; Brain Neoplasms; Dacarbazine; DNA (Cyt

2015
DNMT1 mediates chemosensitivity by reducing methylation of miRNA-20a promoter in glioma cells.
    Experimental & molecular medicine, 2015, Sep-04, Volume: 47

    Topics: Animals; Antineoplastic Agents, Alkylating; Apoptosis; Brain; Brain Neoplasms; Dacarbazine; DNA (Cyt

2015
DNMT1 mediates chemosensitivity by reducing methylation of miRNA-20a promoter in glioma cells.
    Experimental & molecular medicine, 2015, Sep-04, Volume: 47

    Topics: Animals; Antineoplastic Agents, Alkylating; Apoptosis; Brain; Brain Neoplasms; Dacarbazine; DNA (Cyt

2015
Spatiotemporal Evolution of the Primary Glioblastoma Genome.
    Cancer cell, 2015, Sep-14, Volume: 28, Issue:3

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Glioblastoma; Glioma; Humans; Isoci

2015
Spatiotemporal Evolution of the Primary Glioblastoma Genome.
    Cancer cell, 2015, Sep-14, Volume: 28, Issue:3

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Glioblastoma; Glioma; Humans; Isoci

2015
Spatiotemporal Evolution of the Primary Glioblastoma Genome.
    Cancer cell, 2015, Sep-14, Volume: 28, Issue:3

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Glioblastoma; Glioma; Humans; Isoci

2015
Withholding temozolomide in glioblastoma patients with unmethylated MGMT promoter--still a dilemma?
    Neuro-oncology, 2015, Volume: 17, Issue:11

    Topics: Antineoplastic Agents; Brain Neoplasms; Dacarbazine; DNA Methylation; DNA Modification Methylases; D

2015
Withholding temozolomide in glioblastoma patients with unmethylated MGMT promoter--still a dilemma?
    Neuro-oncology, 2015, Volume: 17, Issue:11

    Topics: Antineoplastic Agents; Brain Neoplasms; Dacarbazine; DNA Methylation; DNA Modification Methylases; D

2015
Withholding temozolomide in glioblastoma patients with unmethylated MGMT promoter--still a dilemma?
    Neuro-oncology, 2015, Volume: 17, Issue:11

    Topics: Antineoplastic Agents; Brain Neoplasms; Dacarbazine; DNA Methylation; DNA Modification Methylases; D

2015
Combined Delivery of Temozolomide and Anti-miR221 PNA Using Mesoporous Silica Nanoparticles Induces Apoptosis in Resistant Glioma Cells.
    Small (Weinheim an der Bergstrasse, Germany), 2015, Nov-11, Volume: 11, Issue:42

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Brain Neoplasms; Cell Line, Tumo

2015
Combined Delivery of Temozolomide and Anti-miR221 PNA Using Mesoporous Silica Nanoparticles Induces Apoptosis in Resistant Glioma Cells.
    Small (Weinheim an der Bergstrasse, Germany), 2015, Nov-11, Volume: 11, Issue:42

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Brain Neoplasms; Cell Line, Tumo

2015
Combined Delivery of Temozolomide and Anti-miR221 PNA Using Mesoporous Silica Nanoparticles Induces Apoptosis in Resistant Glioma Cells.
    Small (Weinheim an der Bergstrasse, Germany), 2015, Nov-11, Volume: 11, Issue:42

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Brain Neoplasms; Cell Line, Tumo

2015
Afatinib, an irreversible ErbB family blocker, with protracted temozolomide in recurrent glioblastoma: a case report.
    Oncotarget, 2015, Oct-20, Volume: 6, Issue:32

    Topics: Afatinib; Brain Neoplasms; Clinical Trials, Phase I as Topic; Clinical Trials, Phase II as Topic; Co

2015
Afatinib, an irreversible ErbB family blocker, with protracted temozolomide in recurrent glioblastoma: a case report.
    Oncotarget, 2015, Oct-20, Volume: 6, Issue:32

    Topics: Afatinib; Brain Neoplasms; Clinical Trials, Phase I as Topic; Clinical Trials, Phase II as Topic; Co

2015
Afatinib, an irreversible ErbB family blocker, with protracted temozolomide in recurrent glioblastoma: a case report.
    Oncotarget, 2015, Oct-20, Volume: 6, Issue:32

    Topics: Afatinib; Brain Neoplasms; Clinical Trials, Phase I as Topic; Clinical Trials, Phase II as Topic; Co

2015
Predictors of survival and effect of short (40 Gy) or standard-course (60 Gy) irradiation plus concomitant temozolomide in elderly patients with glioblastoma: a multicenter retrospective study of AINO (Italian Association of Neuro-Oncology).
    Journal of neuro-oncology, 2015, Volume: 125, Issue:2

    Topics: Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Comb

2015
Predictors of survival and effect of short (40 Gy) or standard-course (60 Gy) irradiation plus concomitant temozolomide in elderly patients with glioblastoma: a multicenter retrospective study of AINO (Italian Association of Neuro-Oncology).
    Journal of neuro-oncology, 2015, Volume: 125, Issue:2

    Topics: Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Comb

2015
Predictors of survival and effect of short (40 Gy) or standard-course (60 Gy) irradiation plus concomitant temozolomide in elderly patients with glioblastoma: a multicenter retrospective study of AINO (Italian Association of Neuro-Oncology).
    Journal of neuro-oncology, 2015, Volume: 125, Issue:2

    Topics: Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Comb

2015
A stapled peptide antagonist of MDM2 carried by polymeric micelles sensitizes glioblastoma to temozolomide treatment through p53 activation.
    Journal of controlled release : official journal of the Controlled Release Society, 2015, Nov-28, Volume: 218

    Topics: Animals; Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cell Cycle; Cell Line, Tumor

2015
A stapled peptide antagonist of MDM2 carried by polymeric micelles sensitizes glioblastoma to temozolomide treatment through p53 activation.
    Journal of controlled release : official journal of the Controlled Release Society, 2015, Nov-28, Volume: 218

    Topics: Animals; Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cell Cycle; Cell Line, Tumor

2015
A stapled peptide antagonist of MDM2 carried by polymeric micelles sensitizes glioblastoma to temozolomide treatment through p53 activation.
    Journal of controlled release : official journal of the Controlled Release Society, 2015, Nov-28, Volume: 218

    Topics: Animals; Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cell Cycle; Cell Line, Tumor

2015
Metformin and temozolomide act synergistically to inhibit growth of glioma cells and glioma stem cells in vitro and in vivo.
    Oncotarget, 2015, Oct-20, Volume: 6, Issue:32

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Cell Differentiation; Cell

2015
Metformin and temozolomide act synergistically to inhibit growth of glioma cells and glioma stem cells in vitro and in vivo.
    Oncotarget, 2015, Oct-20, Volume: 6, Issue:32

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Cell Differentiation; Cell

2015
Metformin and temozolomide act synergistically to inhibit growth of glioma cells and glioma stem cells in vitro and in vivo.
    Oncotarget, 2015, Oct-20, Volume: 6, Issue:32

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Cell Differentiation; Cell

2015
Pediatric gliosarcoma treated with adjuvant radiotherapy and temozolomide.
    Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 2015, Volume: 31, Issue:12

    Topics: Adolescent; Antineoplastic Agents, Alkylating; Brain Neoplasms; Child; Combined Modality Therapy; Da

2015
Pediatric gliosarcoma treated with adjuvant radiotherapy and temozolomide.
    Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 2015, Volume: 31, Issue:12

    Topics: Adolescent; Antineoplastic Agents, Alkylating; Brain Neoplasms; Child; Combined Modality Therapy; Da

2015
Pediatric gliosarcoma treated with adjuvant radiotherapy and temozolomide.
    Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 2015, Volume: 31, Issue:12

    Topics: Adolescent; Antineoplastic Agents, Alkylating; Brain Neoplasms; Child; Combined Modality Therapy; Da

2015
Timing of Adjuvant Radiotherapy in Glioblastoma Patients: A Single-Institution Experience With More Than 400 Patients.
    Neurosurgery, 2016, Volume: 78, Issue:5

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Biomarkers; Biopsy; Brain Neoplasms; Combined Modali

2016
Timing of Adjuvant Radiotherapy in Glioblastoma Patients: A Single-Institution Experience With More Than 400 Patients.
    Neurosurgery, 2016, Volume: 78, Issue:5

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Biomarkers; Biopsy; Brain Neoplasms; Combined Modali

2016
Timing of Adjuvant Radiotherapy in Glioblastoma Patients: A Single-Institution Experience With More Than 400 Patients.
    Neurosurgery, 2016, Volume: 78, Issue:5

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Biomarkers; Biopsy; Brain Neoplasms; Combined Modali

2016
The radiosensitivity index predicts for overall survival in glioblastoma.
    Oncotarget, 2015, Oct-27, Volume: 6, Issue:33

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Dacarbazine; Fem

2015
The radiosensitivity index predicts for overall survival in glioblastoma.
    Oncotarget, 2015, Oct-27, Volume: 6, Issue:33

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Dacarbazine; Fem

2015
The radiosensitivity index predicts for overall survival in glioblastoma.
    Oncotarget, 2015, Oct-27, Volume: 6, Issue:33

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Dacarbazine; Fem

2015
Glioblastoma in the elderly: the effect of aggressive and modern therapies on survival.
    Journal of neurosurgery, 2016, Volume: 124, Issue:4

    Topics: Aged; Aged, 80 and over; Aging; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Phytogenic

2016
Glioblastoma in the elderly: the effect of aggressive and modern therapies on survival.
    Journal of neurosurgery, 2016, Volume: 124, Issue:4

    Topics: Aged; Aged, 80 and over; Aging; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Phytogenic

2016
Glioblastoma in the elderly: the effect of aggressive and modern therapies on survival.
    Journal of neurosurgery, 2016, Volume: 124, Issue:4

    Topics: Aged; Aged, 80 and over; Aging; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Phytogenic

2016
Combination of temozolomide and Taxol exerts a synergistic inhibitory effect on Taxol‑resistant glioma cells via inhibition of glucose metabolism.
    Molecular medicine reports, 2015, Volume: 12, Issue:5

    Topics: Antineoplastic Agents; Brain; Brain Neoplasms; Cell Line, Tumor; Dacarbazine; Drug Resistance, Neopl

2015
Combination of temozolomide and Taxol exerts a synergistic inhibitory effect on Taxol‑resistant glioma cells via inhibition of glucose metabolism.
    Molecular medicine reports, 2015, Volume: 12, Issue:5

    Topics: Antineoplastic Agents; Brain; Brain Neoplasms; Cell Line, Tumor; Dacarbazine; Drug Resistance, Neopl

2015
Combination of temozolomide and Taxol exerts a synergistic inhibitory effect on Taxol‑resistant glioma cells via inhibition of glucose metabolism.
    Molecular medicine reports, 2015, Volume: 12, Issue:5

    Topics: Antineoplastic Agents; Brain; Brain Neoplasms; Cell Line, Tumor; Dacarbazine; Drug Resistance, Neopl

2015
Clinical, Radiographic, and Pathologic Findings in Patients Undergoing Reoperation Following Radiation Therapy and Temozolomide for Newly Diagnosed Glioblastoma.
    American journal of clinical oncology, 2017, Volume: 40, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherap

2017
Clinical, Radiographic, and Pathologic Findings in Patients Undergoing Reoperation Following Radiation Therapy and Temozolomide for Newly Diagnosed Glioblastoma.
    American journal of clinical oncology, 2017, Volume: 40, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherap

2017
Clinical, Radiographic, and Pathologic Findings in Patients Undergoing Reoperation Following Radiation Therapy and Temozolomide for Newly Diagnosed Glioblastoma.
    American journal of clinical oncology, 2017, Volume: 40, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherap

2017
Resveratrol sensitizes glioblastoma-initiating cells to temozolomide by inducing cell apoptosis and promoting differentiation.
    Oncology reports, 2016, Volume: 35, Issue:1

    Topics: Apoptosis; Ataxia Telangiectasia Mutated Proteins; Brain Neoplasms; Cell Differentiation; Cell Line,

2016
Resveratrol sensitizes glioblastoma-initiating cells to temozolomide by inducing cell apoptosis and promoting differentiation.
    Oncology reports, 2016, Volume: 35, Issue:1

    Topics: Apoptosis; Ataxia Telangiectasia Mutated Proteins; Brain Neoplasms; Cell Differentiation; Cell Line,

2016
Resveratrol sensitizes glioblastoma-initiating cells to temozolomide by inducing cell apoptosis and promoting differentiation.
    Oncology reports, 2016, Volume: 35, Issue:1

    Topics: Apoptosis; Ataxia Telangiectasia Mutated Proteins; Brain Neoplasms; Cell Differentiation; Cell Line,

2016
IDH mutation and MGMT promoter methylation in glioblastoma: results of a prospective registry.
    Oncotarget, 2015, Dec-01, Volume: 6, Issue:38

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Biomarkers, Tumor; Br

2015
IDH mutation and MGMT promoter methylation in glioblastoma: results of a prospective registry.
    Oncotarget, 2015, Dec-01, Volume: 6, Issue:38

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Biomarkers, Tumor; Br

2015
IDH mutation and MGMT promoter methylation in glioblastoma: results of a prospective registry.
    Oncotarget, 2015, Dec-01, Volume: 6, Issue:38

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Biomarkers, Tumor; Br

2015
Dexamethasone administration during definitive radiation and temozolomide renders a poor prognosis in a retrospective analysis of newly diagnosed glioblastoma patients.
    Radiation oncology (London, England), 2015, Oct-31, Volume: 10

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Brain N

2015
Dexamethasone administration during definitive radiation and temozolomide renders a poor prognosis in a retrospective analysis of newly diagnosed glioblastoma patients.
    Radiation oncology (London, England), 2015, Oct-31, Volume: 10

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Brain N

2015
Dexamethasone administration during definitive radiation and temozolomide renders a poor prognosis in a retrospective analysis of newly diagnosed glioblastoma patients.
    Radiation oncology (London, England), 2015, Oct-31, Volume: 10

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Brain N

2015
Determination of an optimal dosing schedule for combining Irinophore C™ and temozolomide in an orthotopic model of glioblastoma.
    Journal of controlled release : official journal of the Controlled Release Society, 2015, Dec-28, Volume: 220, Issue:Pt A

    Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemoth

2015
Determination of an optimal dosing schedule for combining Irinophore C™ and temozolomide in an orthotopic model of glioblastoma.
    Journal of controlled release : official journal of the Controlled Release Society, 2015, Dec-28, Volume: 220, Issue:Pt A

    Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemoth

2015
Determination of an optimal dosing schedule for combining Irinophore C™ and temozolomide in an orthotopic model of glioblastoma.
    Journal of controlled release : official journal of the Controlled Release Society, 2015, Dec-28, Volume: 220, Issue:Pt A

    Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemoth

2015
Temozolomide reverses doxorubicin resistance by inhibiting P-glycoprotein in malignant glioma cells.
    Journal of neuro-oncology, 2016, Volume: 126, Issue:2

    Topics: Adenosine Triphosphatases; Animals; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfami

2016
Temozolomide reverses doxorubicin resistance by inhibiting P-glycoprotein in malignant glioma cells.
    Journal of neuro-oncology, 2016, Volume: 126, Issue:2

    Topics: Adenosine Triphosphatases; Animals; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfami

2016
Temozolomide reverses doxorubicin resistance by inhibiting P-glycoprotein in malignant glioma cells.
    Journal of neuro-oncology, 2016, Volume: 126, Issue:2

    Topics: Adenosine Triphosphatases; Animals; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfami

2016
Validation of the Effectiveness and Safety of Temozolomide during and after Radiotherapy for Newly Diagnosed Glioblastomas: 10-year Experience of a Single Institution.
    Journal of Korean medical science, 2015, Volume: 30, Issue:11

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chem

2015
Validation of the Effectiveness and Safety of Temozolomide during and after Radiotherapy for Newly Diagnosed Glioblastomas: 10-year Experience of a Single Institution.
    Journal of Korean medical science, 2015, Volume: 30, Issue:11

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chem

2015
Validation of the Effectiveness and Safety of Temozolomide during and after Radiotherapy for Newly Diagnosed Glioblastomas: 10-year Experience of a Single Institution.
    Journal of Korean medical science, 2015, Volume: 30, Issue:11

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chem

2015
Nucleolin antagonist triggers autophagic cell death in human glioblastoma primary cells and decreased in vivo tumor growth in orthotopic brain tumor model.
    Oncotarget, 2015, Dec-08, Volume: 6, Issue:39

    Topics: Adult; Aged; Animals; Antineoplastic Agents, Alkylating; Autophagy; Brain Neoplasms; Cell Line, Tumo

2015
Nucleolin antagonist triggers autophagic cell death in human glioblastoma primary cells and decreased in vivo tumor growth in orthotopic brain tumor model.
    Oncotarget, 2015, Dec-08, Volume: 6, Issue:39

    Topics: Adult; Aged; Animals; Antineoplastic Agents, Alkylating; Autophagy; Brain Neoplasms; Cell Line, Tumo

2015
Nucleolin antagonist triggers autophagic cell death in human glioblastoma primary cells and decreased in vivo tumor growth in orthotopic brain tumor model.
    Oncotarget, 2015, Dec-08, Volume: 6, Issue:39

    Topics: Adult; Aged; Animals; Antineoplastic Agents, Alkylating; Autophagy; Brain Neoplasms; Cell Line, Tumo

2015
Connexin 43 Inhibition Sensitizes Chemoresistant Glioblastoma Cells to Temozolomide.
    Cancer research, 2016, Jan-01, Volume: 76, Issue:1

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Biomimetic Materials; Brain Neoplasms; Cell

2016
Connexin 43 Inhibition Sensitizes Chemoresistant Glioblastoma Cells to Temozolomide.
    Cancer research, 2016, Jan-01, Volume: 76, Issue:1

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Biomimetic Materials; Brain Neoplasms; Cell

2016
Connexin 43 Inhibition Sensitizes Chemoresistant Glioblastoma Cells to Temozolomide.
    Cancer research, 2016, Jan-01, Volume: 76, Issue:1

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Biomimetic Materials; Brain Neoplasms; Cell

2016
Seizure reduction is a prognostic marker in low-grade glioma patients treated with temozolomide.
    Journal of neuro-oncology, 2016, Volume: 126, Issue:2

    Topics: Adult; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Disease-Free Survival; Femal

2016
Seizure reduction is a prognostic marker in low-grade glioma patients treated with temozolomide.
    Journal of neuro-oncology, 2016, Volume: 126, Issue:2

    Topics: Adult; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Disease-Free Survival; Femal

2016
Seizure reduction is a prognostic marker in low-grade glioma patients treated with temozolomide.
    Journal of neuro-oncology, 2016, Volume: 126, Issue:2

    Topics: Adult; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Disease-Free Survival; Femal

2016
Nanoparticle-Delivered Antisense MicroRNA-21 Enhances the Effects of Temozolomide on Glioblastoma Cells.
    Molecular pharmaceutics, 2015, Dec-07, Volume: 12, Issue:12

    Topics: Antineoplastic Agents, Alkylating; Antisense Elements (Genetics); Brain Neoplasms; Caspase 3; Cell L

2015
Nanoparticle-Delivered Antisense MicroRNA-21 Enhances the Effects of Temozolomide on Glioblastoma Cells.
    Molecular pharmaceutics, 2015, Dec-07, Volume: 12, Issue:12

    Topics: Antineoplastic Agents, Alkylating; Antisense Elements (Genetics); Brain Neoplasms; Caspase 3; Cell L

2015
Nanoparticle-Delivered Antisense MicroRNA-21 Enhances the Effects of Temozolomide on Glioblastoma Cells.
    Molecular pharmaceutics, 2015, Dec-07, Volume: 12, Issue:12

    Topics: Antineoplastic Agents, Alkylating; Antisense Elements (Genetics); Brain Neoplasms; Caspase 3; Cell L

2015
The histone demethylase KDM5A is a key factor for the resistance to temozolomide in glioblastoma.
    Cell cycle (Georgetown, Tex.), 2015, Volume: 14, Issue:21

    Topics: Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Brain

2015
The histone demethylase KDM5A is a key factor for the resistance to temozolomide in glioblastoma.
    Cell cycle (Georgetown, Tex.), 2015, Volume: 14, Issue:21

    Topics: Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Brain

2015
The histone demethylase KDM5A is a key factor for the resistance to temozolomide in glioblastoma.
    Cell cycle (Georgetown, Tex.), 2015, Volume: 14, Issue:21

    Topics: Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Brain

2015
Anti-tumor activities of luteolin and silibinin in glioblastoma cells: overexpression of miR-7-1-3p augmented luteolin and silibinin to inhibit autophagy and induce apoptosis in glioblastoma in vivo.
    Apoptosis : an international journal on programmed cell death, 2016, Volume: 21, Issue:3

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Autophagy; Brain Neoplasms; Carm

2016
Anti-tumor activities of luteolin and silibinin in glioblastoma cells: overexpression of miR-7-1-3p augmented luteolin and silibinin to inhibit autophagy and induce apoptosis in glioblastoma in vivo.
    Apoptosis : an international journal on programmed cell death, 2016, Volume: 21, Issue:3

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Autophagy; Brain Neoplasms; Carm

2016
Anti-tumor activities of luteolin and silibinin in glioblastoma cells: overexpression of miR-7-1-3p augmented luteolin and silibinin to inhibit autophagy and induce apoptosis in glioblastoma in vivo.
    Apoptosis : an international journal on programmed cell death, 2016, Volume: 21, Issue:3

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Autophagy; Brain Neoplasms; Carm

2016
Amino acid positron emission tomography to monitor chemotherapy response and predict seizure control and progression-free survival in WHO grade II gliomas.
    Neuro-oncology, 2016, Volume: 18, Issue:5

    Topics: Adult; Amino Acids; Antineoplastic Agents; Area Under Curve; Brain Neoplasms; Dacarbazine; Disease-F

2016
Amino acid positron emission tomography to monitor chemotherapy response and predict seizure control and progression-free survival in WHO grade II gliomas.
    Neuro-oncology, 2016, Volume: 18, Issue:5

    Topics: Adult; Amino Acids; Antineoplastic Agents; Area Under Curve; Brain Neoplasms; Dacarbazine; Disease-F

2016
Amino acid positron emission tomography to monitor chemotherapy response and predict seizure control and progression-free survival in WHO grade II gliomas.
    Neuro-oncology, 2016, Volume: 18, Issue:5

    Topics: Adult; Amino Acids; Antineoplastic Agents; Area Under Curve; Brain Neoplasms; Dacarbazine; Disease-F

2016
Topological robustness analysis of protein interaction networks reveals key targets for overcoming chemotherapy resistance in glioma.
    Scientific reports, 2015, Nov-19, Volume: 5

    Topics: Brain Neoplasms; Cell Line, Tumor; Cell Survival; Dacarbazine; Drug Resistance, Neoplasm; Gene Knock

2015
Topological robustness analysis of protein interaction networks reveals key targets for overcoming chemotherapy resistance in glioma.
    Scientific reports, 2015, Nov-19, Volume: 5

    Topics: Brain Neoplasms; Cell Line, Tumor; Cell Survival; Dacarbazine; Drug Resistance, Neoplasm; Gene Knock

2015
Topological robustness analysis of protein interaction networks reveals key targets for overcoming chemotherapy resistance in glioma.
    Scientific reports, 2015, Nov-19, Volume: 5

    Topics: Brain Neoplasms; Cell Line, Tumor; Cell Survival; Dacarbazine; Drug Resistance, Neoplasm; Gene Knock

2015
Evolving management of low grade glioma: No consensus amongst treating clinicians.
    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2016, Volume: 23

    Topics: Adult; Australia; Brain Neoplasms; Cohort Studies; Consensus; Dacarbazine; Disease Management; Femal

2016
Evolving management of low grade glioma: No consensus amongst treating clinicians.
    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2016, Volume: 23

    Topics: Adult; Australia; Brain Neoplasms; Cohort Studies; Consensus; Dacarbazine; Disease Management; Femal

2016
Evolving management of low grade glioma: No consensus amongst treating clinicians.
    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2016, Volume: 23

    Topics: Adult; Australia; Brain Neoplasms; Cohort Studies; Consensus; Dacarbazine; Disease Management; Femal

2016
Wnt/β-catenin pathway regulates MGMT gene expression in cancer and inhibition of Wnt signalling prevents chemoresistance.
    Nature communications, 2015, Nov-25, Volume: 6

    Topics: Animals; Antineoplastic Agents; Benzeneacetamides; beta Catenin; Brain Neoplasms; Camptothecin; Cele

2015
Wnt/β-catenin pathway regulates MGMT gene expression in cancer and inhibition of Wnt signalling prevents chemoresistance.
    Nature communications, 2015, Nov-25, Volume: 6

    Topics: Animals; Antineoplastic Agents; Benzeneacetamides; beta Catenin; Brain Neoplasms; Camptothecin; Cele

2015
Wnt/β-catenin pathway regulates MGMT gene expression in cancer and inhibition of Wnt signalling prevents chemoresistance.
    Nature communications, 2015, Nov-25, Volume: 6

    Topics: Animals; Antineoplastic Agents; Benzeneacetamides; beta Catenin; Brain Neoplasms; Camptothecin; Cele

2015
Antitumor action of temozolomide, ritonavir and aprepitant against human glioma cells.
    Journal of neuro-oncology, 2016, Volume: 126, Issue:3

    Topics: Antiemetics; Antineoplastic Agents, Alkylating; Apoptosis; Aprepitant; Brain Neoplasms; Cell Prolife

2016
Antitumor action of temozolomide, ritonavir and aprepitant against human glioma cells.
    Journal of neuro-oncology, 2016, Volume: 126, Issue:3

    Topics: Antiemetics; Antineoplastic Agents, Alkylating; Apoptosis; Aprepitant; Brain Neoplasms; Cell Prolife

2016
Antitumor action of temozolomide, ritonavir and aprepitant against human glioma cells.
    Journal of neuro-oncology, 2016, Volume: 126, Issue:3

    Topics: Antiemetics; Antineoplastic Agents, Alkylating; Apoptosis; Aprepitant; Brain Neoplasms; Cell Prolife

2016
Glioblastomas with IDH1/2 mutations have a short clinical history and have a favorable clinical outcome.
    Japanese journal of clinical oncology, 2016, Volume: 46, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Che

2016
Glioblastomas with IDH1/2 mutations have a short clinical history and have a favorable clinical outcome.
    Japanese journal of clinical oncology, 2016, Volume: 46, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Che

2016
Glioblastomas with IDH1/2 mutations have a short clinical history and have a favorable clinical outcome.
    Japanese journal of clinical oncology, 2016, Volume: 46, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Che

2016
Co-expression of Cytoskeletal Protein Adducin 3 and CD133 in Neurospheres and a Temozolomide-resistant Subclone of Glioblastoma.
    Anticancer research, 2015, Volume: 35, Issue:12

    Topics: AC133 Antigen; Antigens, CD; Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Calmodul

2015
Co-expression of Cytoskeletal Protein Adducin 3 and CD133 in Neurospheres and a Temozolomide-resistant Subclone of Glioblastoma.
    Anticancer research, 2015, Volume: 35, Issue:12

    Topics: AC133 Antigen; Antigens, CD; Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Calmodul

2015
Co-expression of Cytoskeletal Protein Adducin 3 and CD133 in Neurospheres and a Temozolomide-resistant Subclone of Glioblastoma.
    Anticancer research, 2015, Volume: 35, Issue:12

    Topics: AC133 Antigen; Antigens, CD; Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Calmodul

2015
SRPX2 Enhances the Epithelial-Mesenchymal Transition and Temozolomide Resistance in Glioblastoma Cells.
    Cellular and molecular neurobiology, 2016, Volume: 36, Issue:7

    Topics: Brain Neoplasms; Cell Line, Tumor; Cell Movement; Dacarbazine; Drug Resistance, Neoplasm; Epithelial

2016
SRPX2 Enhances the Epithelial-Mesenchymal Transition and Temozolomide Resistance in Glioblastoma Cells.
    Cellular and molecular neurobiology, 2016, Volume: 36, Issue:7

    Topics: Brain Neoplasms; Cell Line, Tumor; Cell Movement; Dacarbazine; Drug Resistance, Neoplasm; Epithelial

2016
SRPX2 Enhances the Epithelial-Mesenchymal Transition and Temozolomide Resistance in Glioblastoma Cells.
    Cellular and molecular neurobiology, 2016, Volume: 36, Issue:7

    Topics: Brain Neoplasms; Cell Line, Tumor; Cell Movement; Dacarbazine; Drug Resistance, Neoplasm; Epithelial

2016
Sulforaphane reverses chemo-resistance to temozolomide in glioblastoma cells by NF-κB-dependent pathway downregulating MGMT expression.
    International journal of oncology, 2016, Volume: 48, Issue:2

    Topics: Animals; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Dacarbazine; DNA Modifica

2016
Sulforaphane reverses chemo-resistance to temozolomide in glioblastoma cells by NF-κB-dependent pathway downregulating MGMT expression.
    International journal of oncology, 2016, Volume: 48, Issue:2

    Topics: Animals; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Dacarbazine; DNA Modifica

2016
Sulforaphane reverses chemo-resistance to temozolomide in glioblastoma cells by NF-κB-dependent pathway downregulating MGMT expression.
    International journal of oncology, 2016, Volume: 48, Issue:2

    Topics: Animals; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Dacarbazine; DNA Modifica

2016
Patient-derived glioblastoma cells show significant heterogeneity in treatment responses to the inhibitor-of-apoptosis-protein antagonist birinapant.
    British journal of cancer, 2016, Jan-19, Volume: 114, Issue:2

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Blotting, Western; Brain Neoplas

2016
Patient-derived glioblastoma cells show significant heterogeneity in treatment responses to the inhibitor-of-apoptosis-protein antagonist birinapant.
    British journal of cancer, 2016, Jan-19, Volume: 114, Issue:2

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Blotting, Western; Brain Neoplas

2016
Patient-derived glioblastoma cells show significant heterogeneity in treatment responses to the inhibitor-of-apoptosis-protein antagonist birinapant.
    British journal of cancer, 2016, Jan-19, Volume: 114, Issue:2

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Blotting, Western; Brain Neoplas

2016
Multiple resections and survival of recurrent glioblastoma patients in the temozolomide era.
    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2016, Volume: 24

    Topics: Adult; Aged; Antineoplastic Agents; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Female;

2016
Multiple resections and survival of recurrent glioblastoma patients in the temozolomide era.
    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2016, Volume: 24

    Topics: Adult; Aged; Antineoplastic Agents; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Female;

2016
Multiple resections and survival of recurrent glioblastoma patients in the temozolomide era.
    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2016, Volume: 24

    Topics: Adult; Aged; Antineoplastic Agents; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Female;

2016
A versatile ex vivo technique for assaying tumor angiogenesis and microglia in the brain.
    Oncotarget, 2016, Jan-12, Volume: 7, Issue:2

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; D

2016
A versatile ex vivo technique for assaying tumor angiogenesis and microglia in the brain.
    Oncotarget, 2016, Jan-12, Volume: 7, Issue:2

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; D

2016
A versatile ex vivo technique for assaying tumor angiogenesis and microglia in the brain.
    Oncotarget, 2016, Jan-12, Volume: 7, Issue:2

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; D

2016
High-grade glioma in children and adolescents: a single-center experience.
    Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 2016, Volume: 32, Issue:2

    Topics: Adolescent; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Astro

2016
High-grade glioma in children and adolescents: a single-center experience.
    Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 2016, Volume: 32, Issue:2

    Topics: Adolescent; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Astro

2016
High-grade glioma in children and adolescents: a single-center experience.
    Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 2016, Volume: 32, Issue:2

    Topics: Adolescent; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Astro

2016
Immunohistochemical analysis of O6-methylguanine-DNA methyltransferase (MGMT) protein expression as prognostic marker in glioblastoma patients treated with radiation therapy with concomitant and adjuvant Temozolomide.
    Journal of the Egyptian National Cancer Institute, 2016, Volume: 28, Issue:1

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Biomarkers, Tumor; Brain Neoplasms; Chemotherapy, Ad

2016
Immunohistochemical analysis of O6-methylguanine-DNA methyltransferase (MGMT) protein expression as prognostic marker in glioblastoma patients treated with radiation therapy with concomitant and adjuvant Temozolomide.
    Journal of the Egyptian National Cancer Institute, 2016, Volume: 28, Issue:1

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Biomarkers, Tumor; Brain Neoplasms; Chemotherapy, Ad

2016
Immunohistochemical analysis of O6-methylguanine-DNA methyltransferase (MGMT) protein expression as prognostic marker in glioblastoma patients treated with radiation therapy with concomitant and adjuvant Temozolomide.
    Journal of the Egyptian National Cancer Institute, 2016, Volume: 28, Issue:1

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Biomarkers, Tumor; Brain Neoplasms; Chemotherapy, Ad

2016
A novel drug conjugate, NEO212, targeting proneural and mesenchymal subtypes of patient-derived glioma cancer stem cells.
    Cancer letters, 2016, Feb-28, Volume: 371, Issue:2

    Topics: Animals; Antineoplastic Agents, Alkylating; Apoptosis; Biomarkers, Tumor; Brain Neoplasms; Dacarbazi

2016
A novel drug conjugate, NEO212, targeting proneural and mesenchymal subtypes of patient-derived glioma cancer stem cells.
    Cancer letters, 2016, Feb-28, Volume: 371, Issue:2

    Topics: Animals; Antineoplastic Agents, Alkylating; Apoptosis; Biomarkers, Tumor; Brain Neoplasms; Dacarbazi

2016
A novel drug conjugate, NEO212, targeting proneural and mesenchymal subtypes of patient-derived glioma cancer stem cells.
    Cancer letters, 2016, Feb-28, Volume: 371, Issue:2

    Topics: Animals; Antineoplastic Agents, Alkylating; Apoptosis; Biomarkers, Tumor; Brain Neoplasms; Dacarbazi

2016
EpiBrainRad: an epidemiologic study of the neurotoxicity induced by radiotherapy in high grade glioma patients.
    BMC neurology, 2015, Dec-18, Volume: 15

    Topics: Adult; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant; Cognition Disorde

2015
EpiBrainRad: an epidemiologic study of the neurotoxicity induced by radiotherapy in high grade glioma patients.
    BMC neurology, 2015, Dec-18, Volume: 15

    Topics: Adult; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant; Cognition Disorde

2015
EpiBrainRad: an epidemiologic study of the neurotoxicity induced by radiotherapy in high grade glioma patients.
    BMC neurology, 2015, Dec-18, Volume: 15

    Topics: Adult; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant; Cognition Disorde

2015
Intra-arterial administration improves temozolomide delivery and efficacy in a model of intracerebral metastasis, but has unexpected brain toxicity.
    Journal of neuro-oncology, 2016, Volume: 126, Issue:3

    Topics: Animals; Antineoplastic Agents, Alkylating; Blood-Brain Barrier; Brain Neoplasms; Dacarbazine; Drug

2016
Intra-arterial administration improves temozolomide delivery and efficacy in a model of intracerebral metastasis, but has unexpected brain toxicity.
    Journal of neuro-oncology, 2016, Volume: 126, Issue:3

    Topics: Animals; Antineoplastic Agents, Alkylating; Blood-Brain Barrier; Brain Neoplasms; Dacarbazine; Drug

2016
Intra-arterial administration improves temozolomide delivery and efficacy in a model of intracerebral metastasis, but has unexpected brain toxicity.
    Journal of neuro-oncology, 2016, Volume: 126, Issue:3

    Topics: Animals; Antineoplastic Agents, Alkylating; Blood-Brain Barrier; Brain Neoplasms; Dacarbazine; Drug

2016
High levels of apoptosis are induced in human glioma cell lines by co-administration of peptide nucleic acids targeting miR-221 and miR-222.
    International journal of oncology, 2016, Volume: 48, Issue:3

    Topics: Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cell Survival; Dacarbazine; Drug Resistance, Neoplasm;

2016
High levels of apoptosis are induced in human glioma cell lines by co-administration of peptide nucleic acids targeting miR-221 and miR-222.
    International journal of oncology, 2016, Volume: 48, Issue:3

    Topics: Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cell Survival; Dacarbazine; Drug Resistance, Neoplasm;

2016
High levels of apoptosis are induced in human glioma cell lines by co-administration of peptide nucleic acids targeting miR-221 and miR-222.
    International journal of oncology, 2016, Volume: 48, Issue:3

    Topics: Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cell Survival; Dacarbazine; Drug Resistance, Neoplasm;

2016
Double Blockade of Glioma Cell Proliferation and Migration by Temozolomide Conjugated with NPPB, a Chloride Channel Blocker.
    ACS chemical neuroscience, 2016, Mar-16, Volume: 7, Issue:3

    Topics: Antineoplastic Agents; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cell Movement; Cell Proliferati

2016
Double Blockade of Glioma Cell Proliferation and Migration by Temozolomide Conjugated with NPPB, a Chloride Channel Blocker.
    ACS chemical neuroscience, 2016, Mar-16, Volume: 7, Issue:3

    Topics: Antineoplastic Agents; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cell Movement; Cell Proliferati

2016
Double Blockade of Glioma Cell Proliferation and Migration by Temozolomide Conjugated with NPPB, a Chloride Channel Blocker.
    ACS chemical neuroscience, 2016, Mar-16, Volume: 7, Issue:3

    Topics: Antineoplastic Agents; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cell Movement; Cell Proliferati

2016
Plasmid pORF-hTRAIL targeting to glioma using transferrin-modified polyamidoamine dendrimer.
    Drug design, development and therapy, 2016, Volume: 10

    Topics: Animals; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Dacarbazine; Dendrimers; Gene Expression Regu

2016
Plasmid pORF-hTRAIL targeting to glioma using transferrin-modified polyamidoamine dendrimer.
    Drug design, development and therapy, 2016, Volume: 10

    Topics: Animals; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Dacarbazine; Dendrimers; Gene Expression Regu

2016
Plasmid pORF-hTRAIL targeting to glioma using transferrin-modified polyamidoamine dendrimer.
    Drug design, development and therapy, 2016, Volume: 10

    Topics: Animals; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Dacarbazine; Dendrimers; Gene Expression Regu

2016
In Vitro Validation of Intratumoral Modulation Therapy for Glioblastoma.
    Anticancer research, 2016, Volume: 36, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cell Survival; Chem

2016
In Vitro Validation of Intratumoral Modulation Therapy for Glioblastoma.
    Anticancer research, 2016, Volume: 36, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cell Survival; Chem

2016
In Vitro Validation of Intratumoral Modulation Therapy for Glioblastoma.
    Anticancer research, 2016, Volume: 36, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cell Survival; Chem

2016
MiR-16 modulate temozolomide resistance by regulating BCL-2 in human glioma cells.
    International journal of clinical and experimental pathology, 2015, Volume: 8, Issue:10

    Topics: Antineoplastic Agents, Alkylating; Apoptosis; Blotting, Western; Brain Neoplasms; Cell Line, Tumor;

2015
MiR-16 modulate temozolomide resistance by regulating BCL-2 in human glioma cells.
    International journal of clinical and experimental pathology, 2015, Volume: 8, Issue:10

    Topics: Antineoplastic Agents, Alkylating; Apoptosis; Blotting, Western; Brain Neoplasms; Cell Line, Tumor;

2015
MiR-16 modulate temozolomide resistance by regulating BCL-2 in human glioma cells.
    International journal of clinical and experimental pathology, 2015, Volume: 8, Issue:10

    Topics: Antineoplastic Agents, Alkylating; Apoptosis; Blotting, Western; Brain Neoplasms; Cell Line, Tumor;

2015
Association between treatment-related lymphopenia and overall survival in elderly patients with newly diagnosed glioblastoma.
    Journal of neuro-oncology, 2016, Volume: 127, Issue:2

    Topics: Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Daca

2016
Association between treatment-related lymphopenia and overall survival in elderly patients with newly diagnosed glioblastoma.
    Journal of neuro-oncology, 2016, Volume: 127, Issue:2

    Topics: Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Daca

2016
Association between treatment-related lymphopenia and overall survival in elderly patients with newly diagnosed glioblastoma.
    Journal of neuro-oncology, 2016, Volume: 127, Issue:2

    Topics: Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Daca

2016
Current trends in the management of glioblastoma in a French University Hospital and associated direct costs.
    Journal of clinical pharmacy and therapeutics, 2016, Volume: 41, Issue:1

    Topics: Aged; Antineoplastic Agents; Bevacizumab; Brain Neoplasms; Chemoradiotherapy; Dacarbazine; Drug Cost

2016
Current trends in the management of glioblastoma in a French University Hospital and associated direct costs.
    Journal of clinical pharmacy and therapeutics, 2016, Volume: 41, Issue:1

    Topics: Aged; Antineoplastic Agents; Bevacizumab; Brain Neoplasms; Chemoradiotherapy; Dacarbazine; Drug Cost

2016
Current trends in the management of glioblastoma in a French University Hospital and associated direct costs.
    Journal of clinical pharmacy and therapeutics, 2016, Volume: 41, Issue:1

    Topics: Aged; Antineoplastic Agents; Bevacizumab; Brain Neoplasms; Chemoradiotherapy; Dacarbazine; Drug Cost

2016
Singapore Cancer Network (SCAN) Guidelines for Systemic Therapy of High-Grade Glioma.
    Annals of the Academy of Medicine, Singapore, 2015, Volume: 44, Issue:10

    Topics: Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Astrocytoma; Beva

2015
Singapore Cancer Network (SCAN) Guidelines for Systemic Therapy of High-Grade Glioma.
    Annals of the Academy of Medicine, Singapore, 2015, Volume: 44, Issue:10

    Topics: Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Astrocytoma; Beva

2015
Singapore Cancer Network (SCAN) Guidelines for Systemic Therapy of High-Grade Glioma.
    Annals of the Academy of Medicine, Singapore, 2015, Volume: 44, Issue:10

    Topics: Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Astrocytoma; Beva

2015
SGEF Is Regulated via TWEAK/Fn14/NF-κB Signaling and Promotes Survival by Modulation of the DNA Repair Response to Temozolomide.
    Molecular cancer research : MCR, 2016, Volume: 14, Issue:3

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Cell Survival; Cytokine TWEAK;

2016
SGEF Is Regulated via TWEAK/Fn14/NF-κB Signaling and Promotes Survival by Modulation of the DNA Repair Response to Temozolomide.
    Molecular cancer research : MCR, 2016, Volume: 14, Issue:3

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Cell Survival; Cytokine TWEAK;

2016
SGEF Is Regulated via TWEAK/Fn14/NF-κB Signaling and Promotes Survival by Modulation of the DNA Repair Response to Temozolomide.
    Molecular cancer research : MCR, 2016, Volume: 14, Issue:3

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Cell Survival; Cytokine TWEAK;

2016
Nimotuzumab enhances temozolomide-induced growth suppression of glioma cells expressing mutant EGFR in vivo.
    Cancer medicine, 2016, Volume: 5, Issue:3

    Topics: Animals; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Brain Neoplasms; Cell Line, Tumor

2016
Nimotuzumab enhances temozolomide-induced growth suppression of glioma cells expressing mutant EGFR in vivo.
    Cancer medicine, 2016, Volume: 5, Issue:3

    Topics: Animals; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Brain Neoplasms; Cell Line, Tumor

2016
Nimotuzumab enhances temozolomide-induced growth suppression of glioma cells expressing mutant EGFR in vivo.
    Cancer medicine, 2016, Volume: 5, Issue:3

    Topics: Animals; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Brain Neoplasms; Cell Line, Tumor

2016
Involvement of DDX6 gene in radio- and chemoresistance in glioblastoma.
    International journal of oncology, 2016, Volume: 48, Issue:3

    Topics: Animals; Brain Neoplasms; Cell Proliferation; Cell Survival; Dacarbazine; DEAD-box RNA Helicases; Dr

2016
Involvement of DDX6 gene in radio- and chemoresistance in glioblastoma.
    International journal of oncology, 2016, Volume: 48, Issue:3

    Topics: Animals; Brain Neoplasms; Cell Proliferation; Cell Survival; Dacarbazine; DEAD-box RNA Helicases; Dr

2016
Involvement of DDX6 gene in radio- and chemoresistance in glioblastoma.
    International journal of oncology, 2016, Volume: 48, Issue:3

    Topics: Animals; Brain Neoplasms; Cell Proliferation; Cell Survival; Dacarbazine; DEAD-box RNA Helicases; Dr

2016
Does Valproic Acid or Levetiracetam Improve Survival in Glioblastoma? A Pooled Analysis of Prospective Clinical Trials in Newly Diagnosed Glioblastoma.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2016, Mar-01, Volume: 34, Issue:7

    Topics: Adolescent; Adult; Aged; Anticonvulsants; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemor

2016
Does Valproic Acid or Levetiracetam Improve Survival in Glioblastoma? A Pooled Analysis of Prospective Clinical Trials in Newly Diagnosed Glioblastoma.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2016, Mar-01, Volume: 34, Issue:7

    Topics: Adolescent; Adult; Aged; Anticonvulsants; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemor

2016
Does Valproic Acid or Levetiracetam Improve Survival in Glioblastoma? A Pooled Analysis of Prospective Clinical Trials in Newly Diagnosed Glioblastoma.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2016, Mar-01, Volume: 34, Issue:7

    Topics: Adolescent; Adult; Aged; Anticonvulsants; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemor

2016
Core pathway mutations induce de-differentiation of murine astrocytes into glioblastoma stem cells that are sensitive to radiation but resistant to temozolomide.
    Neuro-oncology, 2016, Volume: 18, Issue:7

    Topics: Animals; Astrocytes; Brain Neoplasms; Cell Differentiation; Cell Line, Tumor; Dacarbazine; Drug Resi

2016
Core pathway mutations induce de-differentiation of murine astrocytes into glioblastoma stem cells that are sensitive to radiation but resistant to temozolomide.
    Neuro-oncology, 2016, Volume: 18, Issue:7

    Topics: Animals; Astrocytes; Brain Neoplasms; Cell Differentiation; Cell Line, Tumor; Dacarbazine; Drug Resi

2016
Core pathway mutations induce de-differentiation of murine astrocytes into glioblastoma stem cells that are sensitive to radiation but resistant to temozolomide.
    Neuro-oncology, 2016, Volume: 18, Issue:7

    Topics: Animals; Astrocytes; Brain Neoplasms; Cell Differentiation; Cell Line, Tumor; Dacarbazine; Drug Resi

2016
Prognostic factors and survival study in high-grade glioma in the elderly.
    British journal of neurosurgery, 2016, Volume: 30, Issue:3

    Topics: Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Thera

2016
Prognostic factors and survival study in high-grade glioma in the elderly.
    British journal of neurosurgery, 2016, Volume: 30, Issue:3

    Topics: Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Thera

2016
Prognostic factors and survival study in high-grade glioma in the elderly.
    British journal of neurosurgery, 2016, Volume: 30, Issue:3

    Topics: Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Thera

2016
Metronomic Doses of Temozolomide Enhance the Efficacy of Carbon Nanotube CpG Immunotherapy in an Invasive Glioma Model.
    PloS one, 2016, Volume: 11, Issue:2

    Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Cell Death; Cell Line, Tumor; Dacarbazine; Disease

2016
Metronomic Doses of Temozolomide Enhance the Efficacy of Carbon Nanotube CpG Immunotherapy in an Invasive Glioma Model.
    PloS one, 2016, Volume: 11, Issue:2

    Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Cell Death; Cell Line, Tumor; Dacarbazine; Disease

2016
Metronomic Doses of Temozolomide Enhance the Efficacy of Carbon Nanotube CpG Immunotherapy in an Invasive Glioma Model.
    PloS one, 2016, Volume: 11, Issue:2

    Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Cell Death; Cell Line, Tumor; Dacarbazine; Disease

2016
Valproic acid, compared to other antiepileptic drugs, is associated with improved overall and progression-free survival in glioblastoma but worse outcome in grade II/III gliomas treated with temozolomide.
    Journal of neuro-oncology, 2016, Volume: 127, Issue:3

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anticonvulsants; Antineoplastic Agents, Alkylating; Brai

2016
Valproic acid, compared to other antiepileptic drugs, is associated with improved overall and progression-free survival in glioblastoma but worse outcome in grade II/III gliomas treated with temozolomide.
    Journal of neuro-oncology, 2016, Volume: 127, Issue:3

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anticonvulsants; Antineoplastic Agents, Alkylating; Brai

2016
Valproic acid, compared to other antiepileptic drugs, is associated with improved overall and progression-free survival in glioblastoma but worse outcome in grade II/III gliomas treated with temozolomide.
    Journal of neuro-oncology, 2016, Volume: 127, Issue:3

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anticonvulsants; Antineoplastic Agents, Alkylating; Brai

2016
Craniospinal irradiation with concomitant and adjuvant temozolomide--a feasibility assessment of toxicity in patients with glioblastoma with a PNET component.
    Journal of neuro-oncology, 2016, Volume: 127, Issue:2

    Topics: Adolescent; Adult; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Chemothera

2016
Craniospinal irradiation with concomitant and adjuvant temozolomide--a feasibility assessment of toxicity in patients with glioblastoma with a PNET component.
    Journal of neuro-oncology, 2016, Volume: 127, Issue:2

    Topics: Adolescent; Adult; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Chemothera

2016
Craniospinal irradiation with concomitant and adjuvant temozolomide--a feasibility assessment of toxicity in patients with glioblastoma with a PNET component.
    Journal of neuro-oncology, 2016, Volume: 127, Issue:2

    Topics: Adolescent; Adult; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Chemothera

2016
Monoamine oxidase A (MAO A) inhibitors decrease glioma progression.
    Oncotarget, 2016, Mar-22, Volume: 7, Issue:12

    Topics: Animals; Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cell Proliferation; Dacarbaz

2016
Monoamine oxidase A (MAO A) inhibitors decrease glioma progression.
    Oncotarget, 2016, Mar-22, Volume: 7, Issue:12

    Topics: Animals; Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cell Proliferation; Dacarbaz

2016
Monoamine oxidase A (MAO A) inhibitors decrease glioma progression.
    Oncotarget, 2016, Mar-22, Volume: 7, Issue:12

    Topics: Animals; Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cell Proliferation; Dacarbaz

2016
Additive antiangiogenesis effect of ginsenoside Rg3 with low-dose metronomic temozolomide on rat glioma cells both in vivo and in vitro.
    Journal of experimental & clinical cancer research : CR, 2016, Feb-13, Volume: 35

    Topics: Administration, Metronomic; Angiogenesis Inhibitors; Animals; Antineoplastic Agents, Alkylating; Ant

2016
Additive antiangiogenesis effect of ginsenoside Rg3 with low-dose metronomic temozolomide on rat glioma cells both in vivo and in vitro.
    Journal of experimental & clinical cancer research : CR, 2016, Feb-13, Volume: 35

    Topics: Administration, Metronomic; Angiogenesis Inhibitors; Animals; Antineoplastic Agents, Alkylating; Ant

2016
Additive antiangiogenesis effect of ginsenoside Rg3 with low-dose metronomic temozolomide on rat glioma cells both in vivo and in vitro.
    Journal of experimental & clinical cancer research : CR, 2016, Feb-13, Volume: 35

    Topics: Administration, Metronomic; Angiogenesis Inhibitors; Animals; Antineoplastic Agents, Alkylating; Ant

2016
mTOR inhibition decreases SOX2-SOX9 mediated glioma stem cell activity and temozolomide resistance.
    Expert opinion on therapeutic targets, 2016, Volume: 20, Issue:4

    Topics: Adult; Animals; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Cell Line, Tumor; D

2016
mTOR inhibition decreases SOX2-SOX9 mediated glioma stem cell activity and temozolomide resistance.
    Expert opinion on therapeutic targets, 2016, Volume: 20, Issue:4

    Topics: Adult; Animals; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Cell Line, Tumor; D

2016
mTOR inhibition decreases SOX2-SOX9 mediated glioma stem cell activity and temozolomide resistance.
    Expert opinion on therapeutic targets, 2016, Volume: 20, Issue:4

    Topics: Adult; Animals; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Cell Line, Tumor; D

2016
Non-thermal atmospheric plasma induces ROS-independent cell death in U373MG glioma cells and augments the cytotoxicity of temozolomide.
    British journal of cancer, 2016, Feb-16, Volume: 114, Issue:4

    Topics: Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Dacarbazine; Drug S

2016
Non-thermal atmospheric plasma induces ROS-independent cell death in U373MG glioma cells and augments the cytotoxicity of temozolomide.
    British journal of cancer, 2016, Feb-16, Volume: 114, Issue:4

    Topics: Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Dacarbazine; Drug S

2016
Non-thermal atmospheric plasma induces ROS-independent cell death in U373MG glioma cells and augments the cytotoxicity of temozolomide.
    British journal of cancer, 2016, Feb-16, Volume: 114, Issue:4

    Topics: Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Dacarbazine; Drug S

2016
Assessment of Quantitative and Allelic MGMT Methylation Patterns as a Prognostic Marker in Glioblastoma.
    Journal of neuropathology and experimental neurology, 2016, Volume: 75, Issue:3

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chi-Square Distribution; Dacarbazin

2016
Assessment of Quantitative and Allelic MGMT Methylation Patterns as a Prognostic Marker in Glioblastoma.
    Journal of neuropathology and experimental neurology, 2016, Volume: 75, Issue:3

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chi-Square Distribution; Dacarbazin

2016
Assessment of Quantitative and Allelic MGMT Methylation Patterns as a Prognostic Marker in Glioblastoma.
    Journal of neuropathology and experimental neurology, 2016, Volume: 75, Issue:3

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chi-Square Distribution; Dacarbazin

2016
MR Studies of Glioblastoma Models Treated with Dual PI3K/mTOR Inhibitor and Temozolomide:Metabolic Changes Are Associated with Enhanced Survival.
    Molecular cancer therapeutics, 2016, Volume: 15, Issue:5

    Topics: Animals; Brain Neoplasms; Cell Line, Tumor; Dacarbazine; Disease Models, Animal; Female; Glioblastom

2016
MR Studies of Glioblastoma Models Treated with Dual PI3K/mTOR Inhibitor and Temozolomide:Metabolic Changes Are Associated with Enhanced Survival.
    Molecular cancer therapeutics, 2016, Volume: 15, Issue:5

    Topics: Animals; Brain Neoplasms; Cell Line, Tumor; Dacarbazine; Disease Models, Animal; Female; Glioblastom

2016
MR Studies of Glioblastoma Models Treated with Dual PI3K/mTOR Inhibitor and Temozolomide:Metabolic Changes Are Associated with Enhanced Survival.
    Molecular cancer therapeutics, 2016, Volume: 15, Issue:5

    Topics: Animals; Brain Neoplasms; Cell Line, Tumor; Dacarbazine; Disease Models, Animal; Female; Glioblastom

2016
BIRC3 is a novel driver of therapeutic resistance in Glioblastoma.
    Scientific reports, 2016, Feb-18, Volume: 6

    Topics: Animals; Baculoviral IAP Repeat-Containing 3 Protein; Brain Neoplasms; Cell Line, Tumor; Dacarbazine

2016
BIRC3 is a novel driver of therapeutic resistance in Glioblastoma.
    Scientific reports, 2016, Feb-18, Volume: 6

    Topics: Animals; Baculoviral IAP Repeat-Containing 3 Protein; Brain Neoplasms; Cell Line, Tumor; Dacarbazine

2016
BIRC3 is a novel driver of therapeutic resistance in Glioblastoma.
    Scientific reports, 2016, Feb-18, Volume: 6

    Topics: Animals; Baculoviral IAP Repeat-Containing 3 Protein; Brain Neoplasms; Cell Line, Tumor; Dacarbazine

2016
Combination Therapy with AKT3 and PI3KCA siRNA Enhances the Antitumor Effect of Temozolomide and Carmustine in T98G Glioblastoma Multiforme Cells.
    BioDrugs : clinical immunotherapeutics, biopharmaceuticals and gene therapy, 2016, Volume: 30, Issue:2

    Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Autophagy; Brain Neoplasms; Carmustine; C

2016
Combination Therapy with AKT3 and PI3KCA siRNA Enhances the Antitumor Effect of Temozolomide and Carmustine in T98G Glioblastoma Multiforme Cells.
    BioDrugs : clinical immunotherapeutics, biopharmaceuticals and gene therapy, 2016, Volume: 30, Issue:2

    Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Autophagy; Brain Neoplasms; Carmustine; C

2016
Combination Therapy with AKT3 and PI3KCA siRNA Enhances the Antitumor Effect of Temozolomide and Carmustine in T98G Glioblastoma Multiforme Cells.
    BioDrugs : clinical immunotherapeutics, biopharmaceuticals and gene therapy, 2016, Volume: 30, Issue:2

    Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Autophagy; Brain Neoplasms; Carmustine; C

2016
SPOCK1 is upregulated in recurrent glioblastoma and contributes to metastasis and Temozolomide resistance.
    Cell proliferation, 2016, Volume: 49, Issue:2

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Cell Movement; Dacarbazine; Dr

2016
SPOCK1 is upregulated in recurrent glioblastoma and contributes to metastasis and Temozolomide resistance.
    Cell proliferation, 2016, Volume: 49, Issue:2

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Cell Movement; Dacarbazine; Dr

2016
SPOCK1 is upregulated in recurrent glioblastoma and contributes to metastasis and Temozolomide resistance.
    Cell proliferation, 2016, Volume: 49, Issue:2

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Cell Movement; Dacarbazine; Dr

2016
Downregulation of miR-137 and miR-6500-3p promotes cell proliferation in pediatric high-grade gliomas.
    Oncotarget, 2016, Apr-12, Volume: 7, Issue:15

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Cycle Proteins; Cell Line, Tumor; Cell Prol

2016
Downregulation of miR-137 and miR-6500-3p promotes cell proliferation in pediatric high-grade gliomas.
    Oncotarget, 2016, Apr-12, Volume: 7, Issue:15

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Cycle Proteins; Cell Line, Tumor; Cell Prol

2016
Downregulation of miR-137 and miR-6500-3p promotes cell proliferation in pediatric high-grade gliomas.
    Oncotarget, 2016, Apr-12, Volume: 7, Issue:15

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Cycle Proteins; Cell Line, Tumor; Cell Prol

2016
Intratumoral heterogeneity identified at the epigenetic, genetic and transcriptional level in glioblastoma.
    Scientific reports, 2016, Mar-04, Volume: 6

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Biomarkers, Pharmacological; Biom

2016
Intratumoral heterogeneity identified at the epigenetic, genetic and transcriptional level in glioblastoma.
    Scientific reports, 2016, Mar-04, Volume: 6

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Biomarkers, Pharmacological; Biom

2016
Intratumoral heterogeneity identified at the epigenetic, genetic and transcriptional level in glioblastoma.
    Scientific reports, 2016, Mar-04, Volume: 6

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Biomarkers, Pharmacological; Biom

2016
Which elderly newly diagnosed glioblastoma patients can benefit from radiotherapy and temozolomide? A PERNO prospective study.
    Journal of neuro-oncology, 2016, Volume: 128, Issue:1

    Topics: Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; DNA Methyl

2016
Which elderly newly diagnosed glioblastoma patients can benefit from radiotherapy and temozolomide? A PERNO prospective study.
    Journal of neuro-oncology, 2016, Volume: 128, Issue:1

    Topics: Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; DNA Methyl

2016
Which elderly newly diagnosed glioblastoma patients can benefit from radiotherapy and temozolomide? A PERNO prospective study.
    Journal of neuro-oncology, 2016, Volume: 128, Issue:1

    Topics: Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; DNA Methyl

2016
Endoplasmic reticulum stress-inducing drugs sensitize glioma cells to temozolomide through downregulation of MGMT, MPG, and Rad51.
    Neuro-oncology, 2016, Volume: 18, Issue:8

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Cell Survival; Dacarb

2016
Endoplasmic reticulum stress-inducing drugs sensitize glioma cells to temozolomide through downregulation of MGMT, MPG, and Rad51.
    Neuro-oncology, 2016, Volume: 18, Issue:8

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Cell Survival; Dacarb

2016
Endoplasmic reticulum stress-inducing drugs sensitize glioma cells to temozolomide through downregulation of MGMT, MPG, and Rad51.
    Neuro-oncology, 2016, Volume: 18, Issue:8

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Cell Survival; Dacarb

2016
The Error-Prone DNA Polymerase κ Promotes Temozolomide Resistance in Glioblastoma through Rad17-Dependent Activation of ATR-Chk1 Signaling.
    Cancer research, 2016, 04-15, Volume: 76, Issue:8

    Topics: Animals; Antineoplastic Agents, Alkylating; Ataxia Telangiectasia Mutated Proteins; Brain Neoplasms;

2016
The Error-Prone DNA Polymerase κ Promotes Temozolomide Resistance in Glioblastoma through Rad17-Dependent Activation of ATR-Chk1 Signaling.
    Cancer research, 2016, 04-15, Volume: 76, Issue:8

    Topics: Animals; Antineoplastic Agents, Alkylating; Ataxia Telangiectasia Mutated Proteins; Brain Neoplasms;

2016
The Error-Prone DNA Polymerase κ Promotes Temozolomide Resistance in Glioblastoma through Rad17-Dependent Activation of ATR-Chk1 Signaling.
    Cancer research, 2016, 04-15, Volume: 76, Issue:8

    Topics: Animals; Antineoplastic Agents, Alkylating; Ataxia Telangiectasia Mutated Proteins; Brain Neoplasms;

2016
Adaptive Immune Response to and Survival Effect of Temozolomide- and Valproic Acid-induced Autophagy in Glioblastoma.
    Anticancer research, 2016, Volume: 36, Issue:3

    Topics: Adaptive Immunity; Animals; Antineoplastic Combined Chemotherapy Protocols; Autophagy; Brain Neoplas

2016
Adaptive Immune Response to and Survival Effect of Temozolomide- and Valproic Acid-induced Autophagy in Glioblastoma.
    Anticancer research, 2016, Volume: 36, Issue:3

    Topics: Adaptive Immunity; Animals; Antineoplastic Combined Chemotherapy Protocols; Autophagy; Brain Neoplas

2016
Adaptive Immune Response to and Survival Effect of Temozolomide- and Valproic Acid-induced Autophagy in Glioblastoma.
    Anticancer research, 2016, Volume: 36, Issue:3

    Topics: Adaptive Immunity; Animals; Antineoplastic Combined Chemotherapy Protocols; Autophagy; Brain Neoplas

2016
Does valproic acid affect tumor growth and improve survival in glioblastomas?
    CNS oncology, 2016, Volume: 5, Issue:2

    Topics: Anticonvulsants; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Differentiation; Cell Prol

2016
Does valproic acid affect tumor growth and improve survival in glioblastomas?
    CNS oncology, 2016, Volume: 5, Issue:2

    Topics: Anticonvulsants; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Differentiation; Cell Prol

2016
Does valproic acid affect tumor growth and improve survival in glioblastomas?
    CNS oncology, 2016, Volume: 5, Issue:2

    Topics: Anticonvulsants; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Differentiation; Cell Prol

2016
Delivery of a drug cache to glioma cells overexpressing platelet-derived growth factor receptor using lipid nanocarriers.
    Nanomedicine (London, England), 2016, Volume: 11, Issue:6

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain; Brain Neoplasms; Cell Line, Tumor; Dacarbazine; D

2016
Delivery of a drug cache to glioma cells overexpressing platelet-derived growth factor receptor using lipid nanocarriers.
    Nanomedicine (London, England), 2016, Volume: 11, Issue:6

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain; Brain Neoplasms; Cell Line, Tumor; Dacarbazine; D

2016
Delivery of a drug cache to glioma cells overexpressing platelet-derived growth factor receptor using lipid nanocarriers.
    Nanomedicine (London, England), 2016, Volume: 11, Issue:6

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain; Brain Neoplasms; Cell Line, Tumor; Dacarbazine; D

2016
Pneumocystis jirovecii pneumonia complicating the progress of a patient with glioblastoma multiforme receiving temozolomide.
    Archivos de bronconeumologia, 2016, Volume: 52, Issue:10

    Topics: Adrenal Cortex Hormones; Aged; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemothera

2016
Pneumocystis jirovecii pneumonia complicating the progress of a patient with glioblastoma multiforme receiving temozolomide.
    Archivos de bronconeumologia, 2016, Volume: 52, Issue:10

    Topics: Adrenal Cortex Hormones; Aged; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemothera

2016
Pneumocystis jirovecii pneumonia complicating the progress of a patient with glioblastoma multiforme receiving temozolomide.
    Archivos de bronconeumologia, 2016, Volume: 52, Issue:10

    Topics: Adrenal Cortex Hormones; Aged; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemothera

2016
Radiotherapy plus concomitant temozolomide in primary gliosarcoma.
    Journal of neuro-oncology, 2016, Volume: 128, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherap

2016
Radiotherapy plus concomitant temozolomide in primary gliosarcoma.
    Journal of neuro-oncology, 2016, Volume: 128, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherap

2016
Radiotherapy plus concomitant temozolomide in primary gliosarcoma.
    Journal of neuro-oncology, 2016, Volume: 128, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherap

2016
A Retrospective Comparative Study of Concomitant Chemoradiotherapy followed by Adjuvant Temozolomide Versus Radiotherapy Alone In Newly Diagnosed Glioblastoma Multiforme - An Experience at Radium Institute, Patna Medical College and Hospital, India.
    The Gulf journal of oncology, 2016, Volume: 1, Issue:20

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Combined Modality Therapy; Da

2016
A Retrospective Comparative Study of Concomitant Chemoradiotherapy followed by Adjuvant Temozolomide Versus Radiotherapy Alone In Newly Diagnosed Glioblastoma Multiforme - An Experience at Radium Institute, Patna Medical College and Hospital, India.
    The Gulf journal of oncology, 2016, Volume: 1, Issue:20

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Combined Modality Therapy; Da

2016
A Retrospective Comparative Study of Concomitant Chemoradiotherapy followed by Adjuvant Temozolomide Versus Radiotherapy Alone In Newly Diagnosed Glioblastoma Multiforme - An Experience at Radium Institute, Patna Medical College and Hospital, India.
    The Gulf journal of oncology, 2016, Volume: 1, Issue:20

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Combined Modality Therapy; Da

2016
MRSI-based molecular imaging of therapy response to temozolomide in preclinical glioblastoma using source analysis.
    NMR in biomedicine, 2016, Volume: 29, Issue:6

    Topics: Animals; Antineoplastic Agents, Alkylating; Biomarkers, Tumor; Brain Neoplasms; Cell Line, Tumor; Da

2016
MRSI-based molecular imaging of therapy response to temozolomide in preclinical glioblastoma using source analysis.
    NMR in biomedicine, 2016, Volume: 29, Issue:6

    Topics: Animals; Antineoplastic Agents, Alkylating; Biomarkers, Tumor; Brain Neoplasms; Cell Line, Tumor; Da

2016
MRSI-based molecular imaging of therapy response to temozolomide in preclinical glioblastoma using source analysis.
    NMR in biomedicine, 2016, Volume: 29, Issue:6

    Topics: Animals; Antineoplastic Agents, Alkylating; Biomarkers, Tumor; Brain Neoplasms; Cell Line, Tumor; Da

2016
Sulfasalazine impacts on ferroptotic cell death and alleviates the tumor microenvironment and glioma-induced brain edema.
    Oncotarget, 2016, Jun-14, Volume: 7, Issue:24

    Topics: Amino Acid Transport System X-AG; Animals; Animals, Newborn; Anti-Inflammatory Agents, Non-Steroidal

2016
Sulfasalazine impacts on ferroptotic cell death and alleviates the tumor microenvironment and glioma-induced brain edema.
    Oncotarget, 2016, Jun-14, Volume: 7, Issue:24

    Topics: Amino Acid Transport System X-AG; Animals; Animals, Newborn; Anti-Inflammatory Agents, Non-Steroidal

2016
Sulfasalazine impacts on ferroptotic cell death and alleviates the tumor microenvironment and glioma-induced brain edema.
    Oncotarget, 2016, Jun-14, Volume: 7, Issue:24

    Topics: Amino Acid Transport System X-AG; Animals; Animals, Newborn; Anti-Inflammatory Agents, Non-Steroidal

2016
Assessment of early response to tumor-treating fields in newly diagnosed glioblastoma using physiologic and metabolic MRI: initial experience.
    CNS oncology, 2016, Volume: 5, Issue:3

    Topics: Anisotropy; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cerebral Blood Volume; Choline; Crea

2016
Assessment of early response to tumor-treating fields in newly diagnosed glioblastoma using physiologic and metabolic MRI: initial experience.
    CNS oncology, 2016, Volume: 5, Issue:3

    Topics: Anisotropy; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cerebral Blood Volume; Choline; Crea

2016
Assessment of early response to tumor-treating fields in newly diagnosed glioblastoma using physiologic and metabolic MRI: initial experience.
    CNS oncology, 2016, Volume: 5, Issue:3

    Topics: Anisotropy; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cerebral Blood Volume; Choline; Crea

2016
Bevacizumab is superior to Temozolomide in causing mitochondrial dysfunction in human brain tumors.
    Neurological research, 2016, Volume: 38, Issue:4

    Topics: Angiogenesis Inhibitors; Antineoplastic Agents, Alkylating; Bevacizumab; Brain Neoplasms; Calcium Ch

2016
Bevacizumab is superior to Temozolomide in causing mitochondrial dysfunction in human brain tumors.
    Neurological research, 2016, Volume: 38, Issue:4

    Topics: Angiogenesis Inhibitors; Antineoplastic Agents, Alkylating; Bevacizumab; Brain Neoplasms; Calcium Ch

2016
Bevacizumab is superior to Temozolomide in causing mitochondrial dysfunction in human brain tumors.
    Neurological research, 2016, Volume: 38, Issue:4

    Topics: Angiogenesis Inhibitors; Antineoplastic Agents, Alkylating; Bevacizumab; Brain Neoplasms; Calcium Ch

2016
KLF8 Promotes Temozolomide Resistance in Glioma Cells via β-Catenin Activation.
    Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 2016, Volume: 38, Issue:4

    Topics: Animals; Antineoplastic Agents, Alkylating; Apoptosis; beta Catenin; Blotting, Western; Brain Neopla

2016
KLF8 Promotes Temozolomide Resistance in Glioma Cells via β-Catenin Activation.
    Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 2016, Volume: 38, Issue:4

    Topics: Animals; Antineoplastic Agents, Alkylating; Apoptosis; beta Catenin; Blotting, Western; Brain Neopla

2016
KLF8 Promotes Temozolomide Resistance in Glioma Cells via β-Catenin Activation.
    Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 2016, Volume: 38, Issue:4

    Topics: Animals; Antineoplastic Agents, Alkylating; Apoptosis; beta Catenin; Blotting, Western; Brain Neopla

2016
Downregulation of HIF-1a sensitizes U251 glioma cells to the temozolomide (TMZ) treatment.
    Experimental cell research, 2016, 05-01, Volume: 343, Issue:2

    Topics: Apoptosis; Brain Neoplasms; Cell Differentiation; Cell Line, Tumor; Cell Movement; Cell Proliferatio

2016
Downregulation of HIF-1a sensitizes U251 glioma cells to the temozolomide (TMZ) treatment.
    Experimental cell research, 2016, 05-01, Volume: 343, Issue:2

    Topics: Apoptosis; Brain Neoplasms; Cell Differentiation; Cell Line, Tumor; Cell Movement; Cell Proliferatio

2016
Downregulation of HIF-1a sensitizes U251 glioma cells to the temozolomide (TMZ) treatment.
    Experimental cell research, 2016, 05-01, Volume: 343, Issue:2

    Topics: Apoptosis; Brain Neoplasms; Cell Differentiation; Cell Line, Tumor; Cell Movement; Cell Proliferatio

2016
Chemical Screening Identifies EUrd as a Novel Inhibitor Against Temozolomide-Resistant Glioblastoma-Initiating Cells.
    Stem cells (Dayton, Ohio), 2016, Volume: 34, Issue:8

    Topics: 5'-Nucleotidase; Animals; Brain Neoplasms; Carcinogenesis; Cell Cycle Checkpoints; Cell Death; Cell

2016
Chemical Screening Identifies EUrd as a Novel Inhibitor Against Temozolomide-Resistant Glioblastoma-Initiating Cells.
    Stem cells (Dayton, Ohio), 2016, Volume: 34, Issue:8

    Topics: 5'-Nucleotidase; Animals; Brain Neoplasms; Carcinogenesis; Cell Cycle Checkpoints; Cell Death; Cell

2016
Chemical Screening Identifies EUrd as a Novel Inhibitor Against Temozolomide-Resistant Glioblastoma-Initiating Cells.
    Stem cells (Dayton, Ohio), 2016, Volume: 34, Issue:8

    Topics: 5'-Nucleotidase; Animals; Brain Neoplasms; Carcinogenesis; Cell Cycle Checkpoints; Cell Death; Cell

2016
KCa3.1 channel inhibition sensitizes malignant gliomas to temozolomide treatment.
    Oncotarget, 2016, May-24, Volume: 7, Issue:21

    Topics: Animals; Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; CDC2 Protein Kinase; Cell Li

2016
KCa3.1 channel inhibition sensitizes malignant gliomas to temozolomide treatment.
    Oncotarget, 2016, May-24, Volume: 7, Issue:21

    Topics: Animals; Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; CDC2 Protein Kinase; Cell Li

2016
KCa3.1 channel inhibition sensitizes malignant gliomas to temozolomide treatment.
    Oncotarget, 2016, May-24, Volume: 7, Issue:21

    Topics: Animals; Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; CDC2 Protein Kinase; Cell Li

2016
Chemotherapy for intracranial ependymoma in adults.
    BMC cancer, 2016, Apr-23, Volume: 16

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Dacarbazine; Dis

2016
Chemotherapy for intracranial ependymoma in adults.
    BMC cancer, 2016, Apr-23, Volume: 16

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Dacarbazine; Dis

2016
Chemotherapy for intracranial ependymoma in adults.
    BMC cancer, 2016, Apr-23, Volume: 16

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Dacarbazine; Dis

2016
CD95 maintains stem cell-like and non-classical EMT programs in primary human glioblastoma cells.
    Cell death & disease, 2016, 04-28, Volume: 7

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Class Ia Phosphatidylinositol 3-Kinase; Dacarbaz

2016
CD95 maintains stem cell-like and non-classical EMT programs in primary human glioblastoma cells.
    Cell death & disease, 2016, 04-28, Volume: 7

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Class Ia Phosphatidylinositol 3-Kinase; Dacarbaz

2016
CD95 maintains stem cell-like and non-classical EMT programs in primary human glioblastoma cells.
    Cell death & disease, 2016, 04-28, Volume: 7

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Class Ia Phosphatidylinositol 3-Kinase; Dacarbaz

2016
Selective Estrogen Receptor β Agonist LY500307 as a Novel Therapeutic Agent for Glioblastoma.
    Scientific reports, 2016, 04-29, Volume: 6

    Topics: Animals; Antineoplastic Agents; Apoptosis; Benzopyrans; Brain Neoplasms; Caspase 3; Cell Line, Tumor

2016
Selective Estrogen Receptor β Agonist LY500307 as a Novel Therapeutic Agent for Glioblastoma.
    Scientific reports, 2016, 04-29, Volume: 6

    Topics: Animals; Antineoplastic Agents; Apoptosis; Benzopyrans; Brain Neoplasms; Caspase 3; Cell Line, Tumor

2016
Selective Estrogen Receptor β Agonist LY500307 as a Novel Therapeutic Agent for Glioblastoma.
    Scientific reports, 2016, 04-29, Volume: 6

    Topics: Animals; Antineoplastic Agents; Apoptosis; Benzopyrans; Brain Neoplasms; Caspase 3; Cell Line, Tumor

2016
Persistent bone marrow depression following short-term treatment with temozolomide.
    BMJ case reports, 2016, Apr-29, Volume: 2016

    Topics: Aged; Anemia, Aplastic; Bone Marrow Diseases; Bone Marrow Failure Disorders; Brain Neoplasms; Dacarb

2016
Persistent bone marrow depression following short-term treatment with temozolomide.
    BMJ case reports, 2016, Apr-29, Volume: 2016

    Topics: Aged; Anemia, Aplastic; Bone Marrow Diseases; Bone Marrow Failure Disorders; Brain Neoplasms; Dacarb

2016
Persistent bone marrow depression following short-term treatment with temozolomide.
    BMJ case reports, 2016, Apr-29, Volume: 2016

    Topics: Aged; Anemia, Aplastic; Bone Marrow Diseases; Bone Marrow Failure Disorders; Brain Neoplasms; Dacarb

2016
Protein Markers Predict Survival in Glioma Patients.
    Molecular & cellular proteomics : MCP, 2016, Volume: 15, Issue:7

    Topics: Adult; Aged; Aged, 80 and over; Biomarkers, Tumor; Brain Neoplasms; Dacarbazine; Female; Glioblastom

2016
Protein Markers Predict Survival in Glioma Patients.
    Molecular & cellular proteomics : MCP, 2016, Volume: 15, Issue:7

    Topics: Adult; Aged; Aged, 80 and over; Biomarkers, Tumor; Brain Neoplasms; Dacarbazine; Female; Glioblastom

2016
Protein Markers Predict Survival in Glioma Patients.
    Molecular & cellular proteomics : MCP, 2016, Volume: 15, Issue:7

    Topics: Adult; Aged; Aged, 80 and over; Biomarkers, Tumor; Brain Neoplasms; Dacarbazine; Female; Glioblastom

2016
Clinical outcome of an alternative fotemustine schedule in elderly patients with recurrent glioblastoma: a mono-institutional retrospective study.
    Journal of neuro-oncology, 2016, Volume: 128, Issue:3

    Topics: Aged; Aged, 80 and over; Antineoplastic Agents; Brain Neoplasms; Dacarbazine; DNA Methylation; DNA M

2016
Clinical outcome of an alternative fotemustine schedule in elderly patients with recurrent glioblastoma: a mono-institutional retrospective study.
    Journal of neuro-oncology, 2016, Volume: 128, Issue:3

    Topics: Aged; Aged, 80 and over; Antineoplastic Agents; Brain Neoplasms; Dacarbazine; DNA Methylation; DNA M

2016
Clinical outcome of an alternative fotemustine schedule in elderly patients with recurrent glioblastoma: a mono-institutional retrospective study.
    Journal of neuro-oncology, 2016, Volume: 128, Issue:3

    Topics: Aged; Aged, 80 and over; Antineoplastic Agents; Brain Neoplasms; Dacarbazine; DNA Methylation; DNA M

2016
Prognostic and therapeutic factors of gliosarcoma from a multi-institutional series.
    Journal of neuro-oncology, 2016, Volume: 129, Issue:1

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbaz

2016
Prognostic and therapeutic factors of gliosarcoma from a multi-institutional series.
    Journal of neuro-oncology, 2016, Volume: 129, Issue:1

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbaz

2016
Prognostic and therapeutic factors of gliosarcoma from a multi-institutional series.
    Journal of neuro-oncology, 2016, Volume: 129, Issue:1

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbaz

2016
Combination therapy in a xenograft model of glioblastoma: enhancement of the antitumor activity of temozolomide by an MDM2 antagonist.
    Journal of neurosurgery, 2017, Volume: 126, Issue:2

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Disease Mode

2017
Combination therapy in a xenograft model of glioblastoma: enhancement of the antitumor activity of temozolomide by an MDM2 antagonist.
    Journal of neurosurgery, 2017, Volume: 126, Issue:2

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Disease Mode

2017
Combination therapy in a xenograft model of glioblastoma: enhancement of the antitumor activity of temozolomide by an MDM2 antagonist.
    Journal of neurosurgery, 2017, Volume: 126, Issue:2

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Disease Mode

2017
Pseudoprogression in children, adolescents and young adults with non-brainstem high grade glioma and diffuse intrinsic pontine glioma.
    Journal of neuro-oncology, 2016, Volume: 129, Issue:1

    Topics: Adolescent; Adult; Antineoplastic Agents, Alkylating; Brain Neoplasms; Brain Stem Neoplasms; Child;

2016
Pseudoprogression in children, adolescents and young adults with non-brainstem high grade glioma and diffuse intrinsic pontine glioma.
    Journal of neuro-oncology, 2016, Volume: 129, Issue:1

    Topics: Adolescent; Adult; Antineoplastic Agents, Alkylating; Brain Neoplasms; Brain Stem Neoplasms; Child;

2016
Pseudoprogression in children, adolescents and young adults with non-brainstem high grade glioma and diffuse intrinsic pontine glioma.
    Journal of neuro-oncology, 2016, Volume: 129, Issue:1

    Topics: Adolescent; Adult; Antineoplastic Agents, Alkylating; Brain Neoplasms; Brain Stem Neoplasms; Child;

2016
Radiologic response to radiation therapy concurrent with temozolomide for progressive simple dysembryoplastic neuroepithelial tumor.
    Acta neurochirurgica, 2016, Volume: 158, Issue:7

    Topics: Adult; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Female; Glioma; Humans; Neop

2016
Radiologic response to radiation therapy concurrent with temozolomide for progressive simple dysembryoplastic neuroepithelial tumor.
    Acta neurochirurgica, 2016, Volume: 158, Issue:7

    Topics: Adult; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Female; Glioma; Humans; Neop

2016
Radiologic response to radiation therapy concurrent with temozolomide for progressive simple dysembryoplastic neuroepithelial tumor.
    Acta neurochirurgica, 2016, Volume: 158, Issue:7

    Topics: Adult; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Female; Glioma; Humans; Neop

2016
NOTCH blockade combined with radiation therapy and temozolomide prolongs survival of orthotopic glioblastoma.
    Oncotarget, 2016, Jul-05, Volume: 7, Issue:27

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Benzazepines; Brain Neoplasms; Cell Line, T

2016
NOTCH blockade combined with radiation therapy and temozolomide prolongs survival of orthotopic glioblastoma.
    Oncotarget, 2016, Jul-05, Volume: 7, Issue:27

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Benzazepines; Brain Neoplasms; Cell Line, T

2016
NOTCH blockade combined with radiation therapy and temozolomide prolongs survival of orthotopic glioblastoma.
    Oncotarget, 2016, Jul-05, Volume: 7, Issue:27

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Benzazepines; Brain Neoplasms; Cell Line, T

2016
Accelerated hyperfractionation plus temozolomide in glioblastoma.
    Radiation oncology (London, England), 2016, May-21, Volume: 11

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chil

2016
Accelerated hyperfractionation plus temozolomide in glioblastoma.
    Radiation oncology (London, England), 2016, May-21, Volume: 11

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chil

2016
Accelerated hyperfractionation plus temozolomide in glioblastoma.
    Radiation oncology (London, England), 2016, May-21, Volume: 11

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chil

2016
Combined-Modality Therapy With Radiation and Chemotherapy for Elderly Patients With Glioblastoma in the Temozolomide Era: A National Cancer Database Analysis.
    JAMA neurology, 2016, 07-01, Volume: 73, Issue:7

    Topics: Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cohort Studies; Combine

2016
Combined-Modality Therapy With Radiation and Chemotherapy for Elderly Patients With Glioblastoma in the Temozolomide Era: A National Cancer Database Analysis.
    JAMA neurology, 2016, 07-01, Volume: 73, Issue:7

    Topics: Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cohort Studies; Combine

2016
Combined-Modality Therapy With Radiation and Chemotherapy for Elderly Patients With Glioblastoma in the Temozolomide Era: A National Cancer Database Analysis.
    JAMA neurology, 2016, 07-01, Volume: 73, Issue:7

    Topics: Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cohort Studies; Combine

2016
Neurobehavioral radiation mitigation to standard brain cancer therapy regimens by Mn(III) n-butoxyethylpyridylporphyrin-based redox modifier.
    Environmental and molecular mutagenesis, 2016, Volume: 57, Issue:5

    Topics: Animals; Antineoplastic Agents; Behavior, Animal; Brain; Brain Neoplasms; Cell Line, Tumor; Cisplati

2016
Neurobehavioral radiation mitigation to standard brain cancer therapy regimens by Mn(III) n-butoxyethylpyridylporphyrin-based redox modifier.
    Environmental and molecular mutagenesis, 2016, Volume: 57, Issue:5

    Topics: Animals; Antineoplastic Agents; Behavior, Animal; Brain; Brain Neoplasms; Cell Line, Tumor; Cisplati

2016
Neurobehavioral radiation mitigation to standard brain cancer therapy regimens by Mn(III) n-butoxyethylpyridylporphyrin-based redox modifier.
    Environmental and molecular mutagenesis, 2016, Volume: 57, Issue:5

    Topics: Animals; Antineoplastic Agents; Behavior, Animal; Brain; Brain Neoplasms; Cell Line, Tumor; Cisplati

2016
Frequent Nek1 overexpression in human gliomas.
    Biochemical and biophysical research communications, 2016, 08-05, Volume: 476, Issue:4

    Topics: Adult; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Dac

2016
Frequent Nek1 overexpression in human gliomas.
    Biochemical and biophysical research communications, 2016, 08-05, Volume: 476, Issue:4

    Topics: Adult; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Dac

2016
Frequent Nek1 overexpression in human gliomas.
    Biochemical and biophysical research communications, 2016, 08-05, Volume: 476, Issue:4

    Topics: Adult; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Dac

2016
Temozolomide induces radiologic pseudoprogression and tumor cell vanishing in oligodendroglioma.
    Neurology, 2016, 07-05, Volume: 87, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Diffusion Magnetic Resonance Imagin

2016
Temozolomide induces radiologic pseudoprogression and tumor cell vanishing in oligodendroglioma.
    Neurology, 2016, 07-05, Volume: 87, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Diffusion Magnetic Resonance Imagin

2016
Temozolomide induces radiologic pseudoprogression and tumor cell vanishing in oligodendroglioma.
    Neurology, 2016, 07-05, Volume: 87, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Diffusion Magnetic Resonance Imagin

2016
HDAC6 promotes cell proliferation and confers resistance to temozolomide in glioblastoma.
    Cancer letters, 2016, 08-28, Volume: 379, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation;

2016
HDAC6 promotes cell proliferation and confers resistance to temozolomide in glioblastoma.
    Cancer letters, 2016, 08-28, Volume: 379, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation;

2016
HDAC6 promotes cell proliferation and confers resistance to temozolomide in glioblastoma.
    Cancer letters, 2016, 08-28, Volume: 379, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation;

2016
Clonal evolution of glioblastoma under therapy.
    Nature genetics, 2016, Volume: 48, Issue:7

    Topics: Antineoplastic Agents, Alkylating; Biomarkers, Tumor; Brain Neoplasms; Cell Proliferation; Clonal Ev

2016
Clonal evolution of glioblastoma under therapy.
    Nature genetics, 2016, Volume: 48, Issue:7

    Topics: Antineoplastic Agents, Alkylating; Biomarkers, Tumor; Brain Neoplasms; Cell Proliferation; Clonal Ev

2016
Clonal evolution of glioblastoma under therapy.
    Nature genetics, 2016, Volume: 48, Issue:7

    Topics: Antineoplastic Agents, Alkylating; Biomarkers, Tumor; Brain Neoplasms; Cell Proliferation; Clonal Ev

2016
Long noncoding RNA RP11-838N2.4 enhances the cytotoxic effects of temozolomide by inhibiting the functions of miR-10a in glioblastoma cell lines.
    Oncotarget, 2016, Jul-12, Volume: 7, Issue:28

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Dacarbazine; Drug Res

2016
Long noncoding RNA RP11-838N2.4 enhances the cytotoxic effects of temozolomide by inhibiting the functions of miR-10a in glioblastoma cell lines.
    Oncotarget, 2016, Jul-12, Volume: 7, Issue:28

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Dacarbazine; Drug Res

2016
Long noncoding RNA RP11-838N2.4 enhances the cytotoxic effects of temozolomide by inhibiting the functions of miR-10a in glioblastoma cell lines.
    Oncotarget, 2016, Jul-12, Volume: 7, Issue:28

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Dacarbazine; Drug Res

2016
Malignant transformation of low-grade gliomas in patients undergoing adjuvant therapy.
    Acta neurologica Belgica, 2017, Volume: 117, Issue:1

    Topics: Adult; Antineoplastic Agents; Brain Neoplasms; Cell Transformation, Neoplastic; Chemoradiotherapy, A

2017
Malignant transformation of low-grade gliomas in patients undergoing adjuvant therapy.
    Acta neurologica Belgica, 2017, Volume: 117, Issue:1

    Topics: Adult; Antineoplastic Agents; Brain Neoplasms; Cell Transformation, Neoplastic; Chemoradiotherapy, A

2017
Malignant transformation of low-grade gliomas in patients undergoing adjuvant therapy.
    Acta neurologica Belgica, 2017, Volume: 117, Issue:1

    Topics: Adult; Antineoplastic Agents; Brain Neoplasms; Cell Transformation, Neoplastic; Chemoradiotherapy, A

2017
Fluoxetine synergizes with temozolomide to induce the CHOP-dependent endoplasmic reticulum stress-related apoptosis pathway in glioma cells.
    Oncology reports, 2016, Volume: 36, Issue:2

    Topics: Animals; Antineoplastic Agents; Apoptosis; Brain Neoplasms; Caspase 3; Cell Line, Tumor; Cell Prolif

2016
Fluoxetine synergizes with temozolomide to induce the CHOP-dependent endoplasmic reticulum stress-related apoptosis pathway in glioma cells.
    Oncology reports, 2016, Volume: 36, Issue:2

    Topics: Animals; Antineoplastic Agents; Apoptosis; Brain Neoplasms; Caspase 3; Cell Line, Tumor; Cell Prolif

2016
Fluoxetine synergizes with temozolomide to induce the CHOP-dependent endoplasmic reticulum stress-related apoptosis pathway in glioma cells.
    Oncology reports, 2016, Volume: 36, Issue:2

    Topics: Animals; Antineoplastic Agents; Apoptosis; Brain Neoplasms; Caspase 3; Cell Line, Tumor; Cell Prolif

2016
ER stress in temozolomide-treated glioblastomas interferes with DNA repair and induces apoptosis.
    Oncotarget, 2016, Jul-12, Volume: 7, Issue:28

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Brain Neoplasms; Cell Line, Tumo

2016
ER stress in temozolomide-treated glioblastomas interferes with DNA repair and induces apoptosis.
    Oncotarget, 2016, Jul-12, Volume: 7, Issue:28

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Brain Neoplasms; Cell Line, Tumo

2016
ER stress in temozolomide-treated glioblastomas interferes with DNA repair and induces apoptosis.
    Oncotarget, 2016, Jul-12, Volume: 7, Issue:28

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Brain Neoplasms; Cell Line, Tumo

2016
Inhibition of MNK pathways enhances cancer cell response to chemotherapy with temozolomide and targeted radionuclide therapy.
    Cellular signalling, 2016, Volume: 28, Issue:9

    Topics: Aniline Compounds; Antineoplastic Agents; Brain Neoplasms; Cell Line, Tumor; Dacarbazine; Eukaryotic

2016
Inhibition of MNK pathways enhances cancer cell response to chemotherapy with temozolomide and targeted radionuclide therapy.
    Cellular signalling, 2016, Volume: 28, Issue:9

    Topics: Aniline Compounds; Antineoplastic Agents; Brain Neoplasms; Cell Line, Tumor; Dacarbazine; Eukaryotic

2016
Inhibition of MNK pathways enhances cancer cell response to chemotherapy with temozolomide and targeted radionuclide therapy.
    Cellular signalling, 2016, Volume: 28, Issue:9

    Topics: Aniline Compounds; Antineoplastic Agents; Brain Neoplasms; Cell Line, Tumor; Dacarbazine; Eukaryotic

2016
Adult-onset atypical teratoid/rhabdoid tumor featuring long spindle cells with nuclear palisading and perivascular pseudorosettes.
    Neuropathology : official journal of the Japanese Society of Neuropathology, 2017, Volume: 37, Issue:1

    Topics: Angiogenesis Inhibitors; Antineoplastic Agents, Alkylating; Bevacizumab; Brain Neoplasms; Combined M

2017
Adult-onset atypical teratoid/rhabdoid tumor featuring long spindle cells with nuclear palisading and perivascular pseudorosettes.
    Neuropathology : official journal of the Japanese Society of Neuropathology, 2017, Volume: 37, Issue:1

    Topics: Angiogenesis Inhibitors; Antineoplastic Agents, Alkylating; Bevacizumab; Brain Neoplasms; Combined M

2017
Adult-onset atypical teratoid/rhabdoid tumor featuring long spindle cells with nuclear palisading and perivascular pseudorosettes.
    Neuropathology : official journal of the Japanese Society of Neuropathology, 2017, Volume: 37, Issue:1

    Topics: Angiogenesis Inhibitors; Antineoplastic Agents, Alkylating; Bevacizumab; Brain Neoplasms; Combined M

2017
Connection between Proliferation Rate and Temozolomide Sensitivity of Primary Glioblastoma Cell Culture and Expression of YB-1 and LRP/MVP.
    Biochemistry. Biokhimiia, 2016, Volume: 81, Issue:6

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Proliferation; Dacarbazine; Gene Expression

2016
Connection between Proliferation Rate and Temozolomide Sensitivity of Primary Glioblastoma Cell Culture and Expression of YB-1 and LRP/MVP.
    Biochemistry. Biokhimiia, 2016, Volume: 81, Issue:6

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Proliferation; Dacarbazine; Gene Expression

2016
Connection between Proliferation Rate and Temozolomide Sensitivity of Primary Glioblastoma Cell Culture and Expression of YB-1 and LRP/MVP.
    Biochemistry. Biokhimiia, 2016, Volume: 81, Issue:6

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Proliferation; Dacarbazine; Gene Expression

2016
Concurrent TERT promoter and BRAF V600E mutation in epithelioid glioblastoma and concomitant low-grade astrocytoma.
    Neuropathology : official journal of the Japanese Society of Neuropathology, 2017, Volume: 37, Issue:1

    Topics: Adolescent; Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neoplasms; Cranial Irradiation; Da

2017
Concurrent TERT promoter and BRAF V600E mutation in epithelioid glioblastoma and concomitant low-grade astrocytoma.
    Neuropathology : official journal of the Japanese Society of Neuropathology, 2017, Volume: 37, Issue:1

    Topics: Adolescent; Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neoplasms; Cranial Irradiation; Da

2017
Concurrent TERT promoter and BRAF V600E mutation in epithelioid glioblastoma and concomitant low-grade astrocytoma.
    Neuropathology : official journal of the Japanese Society of Neuropathology, 2017, Volume: 37, Issue:1

    Topics: Adolescent; Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neoplasms; Cranial Irradiation; Da

2017
Role of irradiation for patients over 80 years old with glioblastoma: a retrospective cohort study.
    Journal of neuro-oncology, 2016, Volume: 129, Issue:2

    Topics: Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cohort Studies; Cranial Irrad

2016
Role of irradiation for patients over 80 years old with glioblastoma: a retrospective cohort study.
    Journal of neuro-oncology, 2016, Volume: 129, Issue:2

    Topics: Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cohort Studies; Cranial Irrad

2016
Role of irradiation for patients over 80 years old with glioblastoma: a retrospective cohort study.
    Journal of neuro-oncology, 2016, Volume: 129, Issue:2

    Topics: Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cohort Studies; Cranial Irrad

2016
Patterns of relapse in patients with high grade glioma receiving combined treatments including stereotactic re-irradiation for a first relapse.
    Cancer radiotherapie : journal de la Societe francaise de radiotherapie oncologique, 2016, Volume: 20, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Bevacizumab; Brain Neoplasms; Camptothecin; C

2016
Patterns of relapse in patients with high grade glioma receiving combined treatments including stereotactic re-irradiation for a first relapse.
    Cancer radiotherapie : journal de la Societe francaise de radiotherapie oncologique, 2016, Volume: 20, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Bevacizumab; Brain Neoplasms; Camptothecin; C

2016
Patterns of relapse in patients with high grade glioma receiving combined treatments including stereotactic re-irradiation for a first relapse.
    Cancer radiotherapie : journal de la Societe francaise de radiotherapie oncologique, 2016, Volume: 20, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Bevacizumab; Brain Neoplasms; Camptothecin; C

2016
NRF2 and glutathione are key resistance mediators to temozolomide in glioma and melanoma cells.
    Oncotarget, 2016, Jul-26, Volume: 7, Issue:30

    Topics: Animals; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Brain Ne

2016
NRF2 and glutathione are key resistance mediators to temozolomide in glioma and melanoma cells.
    Oncotarget, 2016, Jul-26, Volume: 7, Issue:30

    Topics: Animals; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Brain Ne

2016
NRF2 and glutathione are key resistance mediators to temozolomide in glioma and melanoma cells.
    Oncotarget, 2016, Jul-26, Volume: 7, Issue:30

    Topics: Animals; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Brain Ne

2016
Augmented HR Repair Mediates Acquired Temozolomide Resistance in Glioblastoma.
    Molecular cancer research : MCR, 2016, Volume: 14, Issue:10

    Topics: Animals; Brain Neoplasms; Cell Line, Tumor; Dacarbazine; DNA Breaks, Double-Stranded; DNA Modificati

2016
Augmented HR Repair Mediates Acquired Temozolomide Resistance in Glioblastoma.
    Molecular cancer research : MCR, 2016, Volume: 14, Issue:10

    Topics: Animals; Brain Neoplasms; Cell Line, Tumor; Dacarbazine; DNA Breaks, Double-Stranded; DNA Modificati

2016
Augmented HR Repair Mediates Acquired Temozolomide Resistance in Glioblastoma.
    Molecular cancer research : MCR, 2016, Volume: 14, Issue:10

    Topics: Animals; Brain Neoplasms; Cell Line, Tumor; Dacarbazine; DNA Breaks, Double-Stranded; DNA Modificati

2016
Anticancer drug candidate CBL0137, which inhibits histone chaperone FACT, is efficacious in preclinical orthotopic models of temozolomide-responsive and -resistant glioblastoma.
    Neuro-oncology, 2017, 02-01, Volume: 19, Issue:2

    Topics: Animals; Antineoplastic Agents; Apoptosis; Blood-Brain Barrier; Brain Neoplasms; Carbazoles; Cell Pr

2017
Anticancer drug candidate CBL0137, which inhibits histone chaperone FACT, is efficacious in preclinical orthotopic models of temozolomide-responsive and -resistant glioblastoma.
    Neuro-oncology, 2017, 02-01, Volume: 19, Issue:2

    Topics: Animals; Antineoplastic Agents; Apoptosis; Blood-Brain Barrier; Brain Neoplasms; Carbazoles; Cell Pr

2017
Anticancer drug candidate CBL0137, which inhibits histone chaperone FACT, is efficacious in preclinical orthotopic models of temozolomide-responsive and -resistant glioblastoma.
    Neuro-oncology, 2017, 02-01, Volume: 19, Issue:2

    Topics: Animals; Antineoplastic Agents; Apoptosis; Blood-Brain Barrier; Brain Neoplasms; Carbazoles; Cell Pr

2017
Concurrent Chemoradiotherapy with Temozolomide Followed by Adjuvant Temozolomide for Newly Diagnosed Glioblastoma Patients: A Retrospective Multicenter Observation Study in Korea.
    Cancer research and treatment, 2017, Volume: 49, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Biopsy; Brain Neoplasms; Chemorad

2017
Concurrent Chemoradiotherapy with Temozolomide Followed by Adjuvant Temozolomide for Newly Diagnosed Glioblastoma Patients: A Retrospective Multicenter Observation Study in Korea.
    Cancer research and treatment, 2017, Volume: 49, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Biopsy; Brain Neoplasms; Chemorad

2017
Concurrent Chemoradiotherapy with Temozolomide Followed by Adjuvant Temozolomide for Newly Diagnosed Glioblastoma Patients: A Retrospective Multicenter Observation Study in Korea.
    Cancer research and treatment, 2017, Volume: 49, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Biopsy; Brain Neoplasms; Chemorad

2017
miR-29c contribute to glioma cells temozolomide sensitivity by targeting O6-methylguanine-DNA methyltransferases indirectely.
    Oncotarget, 2016, Aug-02, Volume: 7, Issue:31

    Topics: Alkylating Agents; Animals; Brain Neoplasms; Cell Line, Tumor; Cell Survival; Dacarbazine; DNA Repai

2016
miR-29c contribute to glioma cells temozolomide sensitivity by targeting O6-methylguanine-DNA methyltransferases indirectely.
    Oncotarget, 2016, Aug-02, Volume: 7, Issue:31

    Topics: Alkylating Agents; Animals; Brain Neoplasms; Cell Line, Tumor; Cell Survival; Dacarbazine; DNA Repai

2016
miR-29c contribute to glioma cells temozolomide sensitivity by targeting O6-methylguanine-DNA methyltransferases indirectely.
    Oncotarget, 2016, Aug-02, Volume: 7, Issue:31

    Topics: Alkylating Agents; Animals; Brain Neoplasms; Cell Line, Tumor; Cell Survival; Dacarbazine; DNA Repai

2016
OTX015 (MK-8628), a novel BET inhibitor, displays in vitro and in vivo antitumor effects alone and in combination with conventional therapies in glioblastoma models.
    International journal of cancer, 2016, 11-01, Volume: 139, Issue:9

    Topics: Acetanilides; Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Blood-

2016
OTX015 (MK-8628), a novel BET inhibitor, displays in vitro and in vivo antitumor effects alone and in combination with conventional therapies in glioblastoma models.
    International journal of cancer, 2016, 11-01, Volume: 139, Issue:9

    Topics: Acetanilides; Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Blood-

2016
OTX015 (MK-8628), a novel BET inhibitor, displays in vitro and in vivo antitumor effects alone and in combination with conventional therapies in glioblastoma models.
    International journal of cancer, 2016, 11-01, Volume: 139, Issue:9

    Topics: Acetanilides; Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Blood-

2016
The effects of sequential treatments on hippocampal volumes in malignant glioma patients.
    Journal of neuro-oncology, 2016, Volume: 129, Issue:3

    Topics: Adult; Aged; Antineoplastic Agents; Atrophy; Bevacizumab; Brain Neoplasms; Dacarbazine; Female; Glio

2016
The effects of sequential treatments on hippocampal volumes in malignant glioma patients.
    Journal of neuro-oncology, 2016, Volume: 129, Issue:3

    Topics: Adult; Aged; Antineoplastic Agents; Atrophy; Bevacizumab; Brain Neoplasms; Dacarbazine; Female; Glio

2016
The effects of sequential treatments on hippocampal volumes in malignant glioma patients.
    Journal of neuro-oncology, 2016, Volume: 129, Issue:3

    Topics: Adult; Aged; Antineoplastic Agents; Atrophy; Bevacizumab; Brain Neoplasms; Dacarbazine; Female; Glio

2016
Prognostic value of the S100B protein in newly diagnosed and recurrent glioma patients: a serial analysis.
    Journal of neuro-oncology, 2016, Volume: 129, Issue:3

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Female; Gl

2016
Prognostic value of the S100B protein in newly diagnosed and recurrent glioma patients: a serial analysis.
    Journal of neuro-oncology, 2016, Volume: 129, Issue:3

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Female; Gl

2016
Prognostic value of the S100B protein in newly diagnosed and recurrent glioma patients: a serial analysis.
    Journal of neuro-oncology, 2016, Volume: 129, Issue:3

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Female; Gl

2016
Impact of tapering and discontinuation of bevacizumab in patients with progressive glioblastoma.
    Journal of neuro-oncology, 2016, Volume: 129, Issue:3

    Topics: Adult; Aged; Antineoplastic Agents, Immunological; Bevacizumab; Brain Neoplasms; Dacarbazine; Diseas

2016
Impact of tapering and discontinuation of bevacizumab in patients with progressive glioblastoma.
    Journal of neuro-oncology, 2016, Volume: 129, Issue:3

    Topics: Adult; Aged; Antineoplastic Agents, Immunological; Bevacizumab; Brain Neoplasms; Dacarbazine; Diseas

2016
Impact of tapering and discontinuation of bevacizumab in patients with progressive glioblastoma.
    Journal of neuro-oncology, 2016, Volume: 129, Issue:3

    Topics: Adult; Aged; Antineoplastic Agents, Immunological; Bevacizumab; Brain Neoplasms; Dacarbazine; Diseas

2016
Recurrent Glioblastoma: Combination of High Cerebral Blood Flow with MGMT Promoter Methylation Is Associated with Benefit from Low-Dose Temozolomide Rechallenge at First Recurrence.
    Radiology, 2017, Volume: 282, Issue:1

    Topics: Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Blood Volume; Brain Neoplasms; Cerebrova

2017
Recurrent Glioblastoma: Combination of High Cerebral Blood Flow with MGMT Promoter Methylation Is Associated with Benefit from Low-Dose Temozolomide Rechallenge at First Recurrence.
    Radiology, 2017, Volume: 282, Issue:1

    Topics: Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Blood Volume; Brain Neoplasms; Cerebrova

2017
Recurrent Glioblastoma: Combination of High Cerebral Blood Flow with MGMT Promoter Methylation Is Associated with Benefit from Low-Dose Temozolomide Rechallenge at First Recurrence.
    Radiology, 2017, Volume: 282, Issue:1

    Topics: Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Blood Volume; Brain Neoplasms; Cerebrova

2017
Slowing down glioblastoma progression in mice by running or the anti-malarial drug dihydroartemisinin? Induction of oxidative stress in murine glioblastoma therapy.
    Oncotarget, 2016, Aug-30, Volume: 7, Issue:35

    Topics: Animals; Antimalarials; Artemisinins; Brain Neoplasms; Cell Line, Tumor; Combined Modality Therapy;

2016
Slowing down glioblastoma progression in mice by running or the anti-malarial drug dihydroartemisinin? Induction of oxidative stress in murine glioblastoma therapy.
    Oncotarget, 2016, Aug-30, Volume: 7, Issue:35

    Topics: Animals; Antimalarials; Artemisinins; Brain Neoplasms; Cell Line, Tumor; Combined Modality Therapy;

2016
Slowing down glioblastoma progression in mice by running or the anti-malarial drug dihydroartemisinin? Induction of oxidative stress in murine glioblastoma therapy.
    Oncotarget, 2016, Aug-30, Volume: 7, Issue:35

    Topics: Animals; Antimalarials; Artemisinins; Brain Neoplasms; Cell Line, Tumor; Combined Modality Therapy;

2016
miR-423-5p contributes to a malignant phenotype and temozolomide chemoresistance in glioblastomas.
    Neuro-oncology, 2017, Volume: 19, Issue:1

    Topics: Animals; Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cell Cycle Proteins; Cell Pr

2017
miR-423-5p contributes to a malignant phenotype and temozolomide chemoresistance in glioblastomas.
    Neuro-oncology, 2017, Volume: 19, Issue:1

    Topics: Animals; Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cell Cycle Proteins; Cell Pr

2017
miR-423-5p contributes to a malignant phenotype and temozolomide chemoresistance in glioblastomas.
    Neuro-oncology, 2017, Volume: 19, Issue:1

    Topics: Animals; Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cell Cycle Proteins; Cell Pr

2017
RLIP76 Depletion Enhances Autophagic Flux in U251 Cells.
    Cellular and molecular neurobiology, 2017, Volume: 37, Issue:3

    Topics: Apoptosis; ATP-Binding Cassette Transporters; Autophagosomes; Autophagy; Brain Neoplasms; Cell Line,

2017
RLIP76 Depletion Enhances Autophagic Flux in U251 Cells.
    Cellular and molecular neurobiology, 2017, Volume: 37, Issue:3

    Topics: Apoptosis; ATP-Binding Cassette Transporters; Autophagosomes; Autophagy; Brain Neoplasms; Cell Line,

2017
RLIP76 Depletion Enhances Autophagic Flux in U251 Cells.
    Cellular and molecular neurobiology, 2017, Volume: 37, Issue:3

    Topics: Apoptosis; ATP-Binding Cassette Transporters; Autophagosomes; Autophagy; Brain Neoplasms; Cell Line,

2017
The survival significance of a measurable enhancing lesion after completing standard treatment for newly diagnosed glioblastoma.
    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2016, Volume: 34

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Daca

2016
The survival significance of a measurable enhancing lesion after completing standard treatment for newly diagnosed glioblastoma.
    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2016, Volume: 34

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Daca

2016
The survival significance of a measurable enhancing lesion after completing standard treatment for newly diagnosed glioblastoma.
    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2016, Volume: 34

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Daca

2016
Glioblastoma in the elderly - How do we choose who to treat?
    Journal of geriatric oncology, 2016, Volume: 7, Issue:6

    Topics: Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Attitude of Health Personnel; Brain Neop

2016
Glioblastoma in the elderly - How do we choose who to treat?
    Journal of geriatric oncology, 2016, Volume: 7, Issue:6

    Topics: Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Attitude of Health Personnel; Brain Neop

2016
Glioblastoma in the elderly - How do we choose who to treat?
    Journal of geriatric oncology, 2016, Volume: 7, Issue:6

    Topics: Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Attitude of Health Personnel; Brain Neop

2016
Antidepressant drugs can modify cytotoxic action of temozolomide.
    European journal of cancer care, 2017, Volume: 26, Issue:5

    Topics: Antidepressive Agents; Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cell Division;

2017
Antidepressant drugs can modify cytotoxic action of temozolomide.
    European journal of cancer care, 2017, Volume: 26, Issue:5

    Topics: Antidepressive Agents; Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cell Division;

2017
Antidepressant drugs can modify cytotoxic action of temozolomide.
    European journal of cancer care, 2017, Volume: 26, Issue:5

    Topics: Antidepressive Agents; Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cell Division;

2017
Analysis of Treatment Tolerance and Factors Associated with Overall Survival in Elderly Patients with Glioblastoma.
    World neurosurgery, 2016, Volume: 95

    Topics: Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy, Adju

2016
Analysis of Treatment Tolerance and Factors Associated with Overall Survival in Elderly Patients with Glioblastoma.
    World neurosurgery, 2016, Volume: 95

    Topics: Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy, Adju

2016
Analysis of Treatment Tolerance and Factors Associated with Overall Survival in Elderly Patients with Glioblastoma.
    World neurosurgery, 2016, Volume: 95

    Topics: Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy, Adju

2016
HMGA1 silencing reduces stemness and temozolomide resistance in glioblastoma stem cells.
    Expert opinion on therapeutic targets, 2016, Volume: 20, Issue:10

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Dacarbazine; Drug Resistance,

2016
HMGA1 silencing reduces stemness and temozolomide resistance in glioblastoma stem cells.
    Expert opinion on therapeutic targets, 2016, Volume: 20, Issue:10

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Dacarbazine; Drug Resistance,

2016
HMGA1 silencing reduces stemness and temozolomide resistance in glioblastoma stem cells.
    Expert opinion on therapeutic targets, 2016, Volume: 20, Issue:10

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Dacarbazine; Drug Resistance,

2016
Targeting hyperactivated DNA-PKcs by KU0060648 inhibits glioma progression and enhances temozolomide therapy via suppression of AKT signaling.
    Oncotarget, 2016, Aug-23, Volume: 7, Issue:34

    Topics: Animals; Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Dacarbazin

2016
Targeting hyperactivated DNA-PKcs by KU0060648 inhibits glioma progression and enhances temozolomide therapy via suppression of AKT signaling.
    Oncotarget, 2016, Aug-23, Volume: 7, Issue:34

    Topics: Animals; Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Dacarbazin

2016
Targeting hyperactivated DNA-PKcs by KU0060648 inhibits glioma progression and enhances temozolomide therapy via suppression of AKT signaling.
    Oncotarget, 2016, Aug-23, Volume: 7, Issue:34

    Topics: Animals; Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Dacarbazin

2016
Integrin αVβ3 silencing sensitizes malignant glioma cells to temozolomide by suppression of homologous recombination repair.
    Oncotarget, 2017, Apr-25, Volume: 8, Issue:17

    Topics: Animals; Antineoplastic Agents, Alkylating; Apoptosis; Apoptosis Regulatory Proteins; Brain Neoplasm

2017
Integrin αVβ3 silencing sensitizes malignant glioma cells to temozolomide by suppression of homologous recombination repair.
    Oncotarget, 2017, Apr-25, Volume: 8, Issue:17

    Topics: Animals; Antineoplastic Agents, Alkylating; Apoptosis; Apoptosis Regulatory Proteins; Brain Neoplasm

2017
Integrin αVβ3 silencing sensitizes malignant glioma cells to temozolomide by suppression of homologous recombination repair.
    Oncotarget, 2017, Apr-25, Volume: 8, Issue:17

    Topics: Animals; Antineoplastic Agents, Alkylating; Apoptosis; Apoptosis Regulatory Proteins; Brain Neoplasm

2017
Predicting the cell death responsiveness and sensitization of glioma cells to TRAIL and temozolomide.
    Oncotarget, 2016, Sep-20, Volume: 7, Issue:38

    Topics: Antineoplastic Agents, Alkylating; Apoptosis; Biphenyl Compounds; Brain Neoplasms; Cell Line, Tumor;

2016
Predicting the cell death responsiveness and sensitization of glioma cells to TRAIL and temozolomide.
    Oncotarget, 2016, Sep-20, Volume: 7, Issue:38

    Topics: Antineoplastic Agents, Alkylating; Apoptosis; Biphenyl Compounds; Brain Neoplasms; Cell Line, Tumor;

2016
Predicting the cell death responsiveness and sensitization of glioma cells to TRAIL and temozolomide.
    Oncotarget, 2016, Sep-20, Volume: 7, Issue:38

    Topics: Antineoplastic Agents, Alkylating; Apoptosis; Biphenyl Compounds; Brain Neoplasms; Cell Line, Tumor;

2016
A combination of TERT promoter mutation and MGMT methylation status predicts clinically relevant subgroups of newly diagnosed glioblastomas.
    Acta neuropathologica communications, 2016, 08-08, Volume: 4, Issue:1

    Topics: Adult; Antineoplastic Agents, Alkylating; Biomarkers, Tumor; Brain Neoplasms; Cohort Studies; Combin

2016
A combination of TERT promoter mutation and MGMT methylation status predicts clinically relevant subgroups of newly diagnosed glioblastomas.
    Acta neuropathologica communications, 2016, 08-08, Volume: 4, Issue:1

    Topics: Adult; Antineoplastic Agents, Alkylating; Biomarkers, Tumor; Brain Neoplasms; Cohort Studies; Combin

2016
A combination of TERT promoter mutation and MGMT methylation status predicts clinically relevant subgroups of newly diagnosed glioblastomas.
    Acta neuropathologica communications, 2016, 08-08, Volume: 4, Issue:1

    Topics: Adult; Antineoplastic Agents, Alkylating; Biomarkers, Tumor; Brain Neoplasms; Cohort Studies; Combin

2016
GSK621 Targets Glioma Cells via Activating AMP-Activated Protein Kinase Signalings.
    PloS one, 2016, Volume: 11, Issue:8

    Topics: AMP-Activated Protein Kinases; Antineoplastic Agents; Apoptosis; Brain Neoplasms; Cell Line, Tumor;

2016
GSK621 Targets Glioma Cells via Activating AMP-Activated Protein Kinase Signalings.
    PloS one, 2016, Volume: 11, Issue:8

    Topics: AMP-Activated Protein Kinases; Antineoplastic Agents; Apoptosis; Brain Neoplasms; Cell Line, Tumor;

2016
GSK621 Targets Glioma Cells via Activating AMP-Activated Protein Kinase Signalings.
    PloS one, 2016, Volume: 11, Issue:8

    Topics: AMP-Activated Protein Kinases; Antineoplastic Agents; Apoptosis; Brain Neoplasms; Cell Line, Tumor;

2016
Serial analysis of 3D H-1 MRSI for patients with newly diagnosed GBM treated with combination therapy that includes bevacizumab.
    Journal of neuro-oncology, 2016, Volume: 130, Issue:1

    Topics: Adult; Aged; Antineoplastic Agents, Immunological; Aspartic Acid; Bevacizumab; Brain Neoplasms; Chol

2016
Serial analysis of 3D H-1 MRSI for patients with newly diagnosed GBM treated with combination therapy that includes bevacizumab.
    Journal of neuro-oncology, 2016, Volume: 130, Issue:1

    Topics: Adult; Aged; Antineoplastic Agents, Immunological; Aspartic Acid; Bevacizumab; Brain Neoplasms; Chol

2016
Serial analysis of 3D H-1 MRSI for patients with newly diagnosed GBM treated with combination therapy that includes bevacizumab.
    Journal of neuro-oncology, 2016, Volume: 130, Issue:1

    Topics: Adult; Aged; Antineoplastic Agents, Immunological; Aspartic Acid; Bevacizumab; Brain Neoplasms; Chol

2016
Validation of the high-performance of pyrosequencing for clinical MGMT testing on a cohort of glioblastoma patients from a prospective dedicated multicentric trial.
    Oncotarget, 2016, 09-20, Volume: 7, Issue:38

    Topics: Adult; Aged; Brain Neoplasms; Dacarbazine; Disease-Free Survival; DNA Methylation; DNA Modification

2016
Validation of the high-performance of pyrosequencing for clinical MGMT testing on a cohort of glioblastoma patients from a prospective dedicated multicentric trial.
    Oncotarget, 2016, 09-20, Volume: 7, Issue:38

    Topics: Adult; Aged; Brain Neoplasms; Dacarbazine; Disease-Free Survival; DNA Methylation; DNA Modification

2016
Validation of the high-performance of pyrosequencing for clinical MGMT testing on a cohort of glioblastoma patients from a prospective dedicated multicentric trial.
    Oncotarget, 2016, 09-20, Volume: 7, Issue:38

    Topics: Adult; Aged; Brain Neoplasms; Dacarbazine; Disease-Free Survival; DNA Methylation; DNA Modification

2016
Molecular dissection of the valproic acid effects on glioma cells.
    Oncotarget, 2016, Sep-27, Volume: 7, Issue:39

    Topics: Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Chromatin; Dacarbazine; Decision Support Syst

2016
Molecular dissection of the valproic acid effects on glioma cells.
    Oncotarget, 2016, Sep-27, Volume: 7, Issue:39

    Topics: Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Chromatin; Dacarbazine; Decision Support Syst

2016
Molecular dissection of the valproic acid effects on glioma cells.
    Oncotarget, 2016, Sep-27, Volume: 7, Issue:39

    Topics: Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Chromatin; Dacarbazine; Decision Support Syst

2016
Zinc enhances temozolomide cytotoxicity in glioblastoma multiforme model systems.
    Oncotarget, 2016, Nov-15, Volume: 7, Issue:46

    Topics: Animals; Antineoplastic Agents, Alkylating; Apoptosis; Apoptosis Regulatory Proteins; bcl-2-Associat

2016
Zinc enhances temozolomide cytotoxicity in glioblastoma multiforme model systems.
    Oncotarget, 2016, Nov-15, Volume: 7, Issue:46

    Topics: Animals; Antineoplastic Agents, Alkylating; Apoptosis; Apoptosis Regulatory Proteins; bcl-2-Associat

2016
Zinc enhances temozolomide cytotoxicity in glioblastoma multiforme model systems.
    Oncotarget, 2016, Nov-15, Volume: 7, Issue:46

    Topics: Animals; Antineoplastic Agents, Alkylating; Apoptosis; Apoptosis Regulatory Proteins; bcl-2-Associat

2016
Reversibility of glioma stem cells' phenotypes explains their complex in vitro and in vivo behavior: Discovery of a novel neurosphere-specific enzyme, cGMP-dependent protein kinase 1, using the genomic landscape of human glioma stem cells as a discovery t
    Oncotarget, 2016, 09-27, Volume: 7, Issue:39

    Topics: Animals; Apoptosis; Biomarkers, Tumor; Brain Neoplasms; Cell Line, Tumor; Cell Movement; Cell Prolif

2016
Reversibility of glioma stem cells' phenotypes explains their complex in vitro and in vivo behavior: Discovery of a novel neurosphere-specific enzyme, cGMP-dependent protein kinase 1, using the genomic landscape of human glioma stem cells as a discovery t
    Oncotarget, 2016, 09-27, Volume: 7, Issue:39

    Topics: Animals; Apoptosis; Biomarkers, Tumor; Brain Neoplasms; Cell Line, Tumor; Cell Movement; Cell Prolif

2016
Reversibility of glioma stem cells' phenotypes explains their complex in vitro and in vivo behavior: Discovery of a novel neurosphere-specific enzyme, cGMP-dependent protein kinase 1, using the genomic landscape of human glioma stem cells as a discovery t
    Oncotarget, 2016, 09-27, Volume: 7, Issue:39

    Topics: Animals; Apoptosis; Biomarkers, Tumor; Brain Neoplasms; Cell Line, Tumor; Cell Movement; Cell Prolif

2016
Changes in PlGF and MET-HGF expressions in paired initial and recurrent glioblastoma.
    Journal of neuro-oncology, 2016, Volume: 130, Issue:3

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Dose-Response Relation

2016
Changes in PlGF and MET-HGF expressions in paired initial and recurrent glioblastoma.
    Journal of neuro-oncology, 2016, Volume: 130, Issue:3

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Dose-Response Relation

2016
Changes in PlGF and MET-HGF expressions in paired initial and recurrent glioblastoma.
    Journal of neuro-oncology, 2016, Volume: 130, Issue:3

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Dose-Response Relation

2016
Association of early changes in 1H MRSI parameters with survival for patients with newly diagnosed glioblastoma receiving a multimodality treatment regimen.
    Neuro-oncology, 2017, 03-01, Volume: 19, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Cho

2017
Association of early changes in 1H MRSI parameters with survival for patients with newly diagnosed glioblastoma receiving a multimodality treatment regimen.
    Neuro-oncology, 2017, 03-01, Volume: 19, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Cho

2017
Association of early changes in 1H MRSI parameters with survival for patients with newly diagnosed glioblastoma receiving a multimodality treatment regimen.
    Neuro-oncology, 2017, 03-01, Volume: 19, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Cho

2017
Inhibiting stemness and invasive properties of glioblastoma tumorsphere by combined treatment with temozolomide and a newly designed biguanide (HL156A).
    Oncotarget, 2016, 10-04, Volume: 7, Issue:40

    Topics: Animals; Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cell Proliferation; Dacarbaz

2016
Inhibiting stemness and invasive properties of glioblastoma tumorsphere by combined treatment with temozolomide and a newly designed biguanide (HL156A).
    Oncotarget, 2016, 10-04, Volume: 7, Issue:40

    Topics: Animals; Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cell Proliferation; Dacarbaz

2016
Inhibiting stemness and invasive properties of glioblastoma tumorsphere by combined treatment with temozolomide and a newly designed biguanide (HL156A).
    Oncotarget, 2016, 10-04, Volume: 7, Issue:40

    Topics: Animals; Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cell Proliferation; Dacarbaz

2016
Targeting hexokinase 2 enhances response to radio-chemotherapy in glioblastoma.
    Oncotarget, 2016, 10-25, Volume: 7, Issue:43

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; C

2016
Targeting hexokinase 2 enhances response to radio-chemotherapy in glioblastoma.
    Oncotarget, 2016, 10-25, Volume: 7, Issue:43

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; C

2016
Targeting hexokinase 2 enhances response to radio-chemotherapy in glioblastoma.
    Oncotarget, 2016, 10-25, Volume: 7, Issue:43

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; C

2016
Radiation combined with temozolomide contraindicated for young adults diagnosed with anaplastic glioma.
    Oncotarget, 2016, Nov-29, Volume: 7, Issue:48

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chin

2016
Radiation combined with temozolomide contraindicated for young adults diagnosed with anaplastic glioma.
    Oncotarget, 2016, Nov-29, Volume: 7, Issue:48

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chin

2016
Radiation combined with temozolomide contraindicated for young adults diagnosed with anaplastic glioma.
    Oncotarget, 2016, Nov-29, Volume: 7, Issue:48

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chin

2016
Widely metastatic atypical pituitary adenoma with mTOR pathway STK11(F298L) mutation treated with everolimus therapy.
    CNS oncology, 2016, Volume: 5, Issue:4

    Topics: Adenoma; Adrenocorticotropic Hormone; AMP-Activated Protein Kinase Kinases; Antineoplastic Agents; B

2016
Widely metastatic atypical pituitary adenoma with mTOR pathway STK11(F298L) mutation treated with everolimus therapy.
    CNS oncology, 2016, Volume: 5, Issue:4

    Topics: Adenoma; Adrenocorticotropic Hormone; AMP-Activated Protein Kinase Kinases; Antineoplastic Agents; B

2016
Widely metastatic atypical pituitary adenoma with mTOR pathway STK11(F298L) mutation treated with everolimus therapy.
    CNS oncology, 2016, Volume: 5, Issue:4

    Topics: Adenoma; Adrenocorticotropic Hormone; AMP-Activated Protein Kinase Kinases; Antineoplastic Agents; B

2016
Artesunate enhances the therapeutic response of glioma cells to temozolomide by inhibition of homologous recombination and senescence.
    Oncotarget, 2016, Oct-11, Volume: 7, Issue:41

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Artemisinins; Artesunate; Brain Neoplasms;

2016
Artesunate enhances the therapeutic response of glioma cells to temozolomide by inhibition of homologous recombination and senescence.
    Oncotarget, 2016, Oct-11, Volume: 7, Issue:41

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Artemisinins; Artesunate; Brain Neoplasms;

2016
Artesunate enhances the therapeutic response of glioma cells to temozolomide by inhibition of homologous recombination and senescence.
    Oncotarget, 2016, Oct-11, Volume: 7, Issue:41

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Artemisinins; Artesunate; Brain Neoplasms;

2016
MRI and 11C-methyl-L-methionine PET Differentiate Bevacizumab True Responders After Initiating Therapy for Recurrent Glioblastoma.
    Clinical nuclear medicine, 2016, Volume: 41, Issue:11

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Brain Neoplasms; Dacarbazi

2016
MRI and 11C-methyl-L-methionine PET Differentiate Bevacizumab True Responders After Initiating Therapy for Recurrent Glioblastoma.
    Clinical nuclear medicine, 2016, Volume: 41, Issue:11

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Brain Neoplasms; Dacarbazi

2016
MRI and 11C-methyl-L-methionine PET Differentiate Bevacizumab True Responders After Initiating Therapy for Recurrent Glioblastoma.
    Clinical nuclear medicine, 2016, Volume: 41, Issue:11

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Brain Neoplasms; Dacarbazi

2016
Increased Expression of System xc- in Glioblastoma Confers an Altered Metabolic State and Temozolomide Resistance.
    Molecular cancer research : MCR, 2016, Volume: 14, Issue:12

    Topics: Amino Acid Transport System y+; Animals; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Cell

2016
Increased Expression of System xc- in Glioblastoma Confers an Altered Metabolic State and Temozolomide Resistance.
    Molecular cancer research : MCR, 2016, Volume: 14, Issue:12

    Topics: Amino Acid Transport System y+; Animals; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Cell

2016
Increased Expression of System xc- in Glioblastoma Confers an Altered Metabolic State and Temozolomide Resistance.
    Molecular cancer research : MCR, 2016, Volume: 14, Issue:12

    Topics: Amino Acid Transport System y+; Animals; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Cell

2016
Targeting Gliomas: Can a New Alkylating Hybrid Compound Make a Difference?
    ACS chemical neuroscience, 2017, 01-18, Volume: 8, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Apoptosis; ATP Binding Cassette Transporter, Subfamily B, Member

2017
Targeting Gliomas: Can a New Alkylating Hybrid Compound Make a Difference?
    ACS chemical neuroscience, 2017, 01-18, Volume: 8, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Apoptosis; ATP Binding Cassette Transporter, Subfamily B, Member

2017
Targeting Gliomas: Can a New Alkylating Hybrid Compound Make a Difference?
    ACS chemical neuroscience, 2017, 01-18, Volume: 8, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Apoptosis; ATP Binding Cassette Transporter, Subfamily B, Member

2017
Combination of Palonosetron, Aprepitant, and Dexamethasone Effectively Controls Chemotherapy-induced Nausea and Vomiting in Patients Treated with Concomitant Temozolomide and Radiotherapy: Results of a Prospective Study.
    Neurologia medico-chirurgica, 2016, Nov-15, Volume: 56, Issue:11

    Topics: Adult; Aged; Antiemetics; Antineoplastic Agents, Alkylating; Aprepitant; Brain Neoplasms; Dacarbazin

2016
Combination of Palonosetron, Aprepitant, and Dexamethasone Effectively Controls Chemotherapy-induced Nausea and Vomiting in Patients Treated with Concomitant Temozolomide and Radiotherapy: Results of a Prospective Study.
    Neurologia medico-chirurgica, 2016, Nov-15, Volume: 56, Issue:11

    Topics: Adult; Aged; Antiemetics; Antineoplastic Agents, Alkylating; Aprepitant; Brain Neoplasms; Dacarbazin

2016
Combination of Palonosetron, Aprepitant, and Dexamethasone Effectively Controls Chemotherapy-induced Nausea and Vomiting in Patients Treated with Concomitant Temozolomide and Radiotherapy: Results of a Prospective Study.
    Neurologia medico-chirurgica, 2016, Nov-15, Volume: 56, Issue:11

    Topics: Adult; Aged; Antiemetics; Antineoplastic Agents, Alkylating; Aprepitant; Brain Neoplasms; Dacarbazin

2016
FK228 augmented temozolomide sensitivity in human glioma cells by blocking PI3K/AKT/mTOR signal pathways.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2016, Volume: 84

    Topics: Animals; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Dacarbazine; Depsipeptide

2016
FK228 augmented temozolomide sensitivity in human glioma cells by blocking PI3K/AKT/mTOR signal pathways.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2016, Volume: 84

    Topics: Animals; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Dacarbazine; Depsipeptide

2016
FK228 augmented temozolomide sensitivity in human glioma cells by blocking PI3K/AKT/mTOR signal pathways.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2016, Volume: 84

    Topics: Animals; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Dacarbazine; Depsipeptide

2016
Permeability Surface Area Product Using Perfusion Computed Tomography Is a Valuable Prognostic Factor in Glioblastomas Treated with Radiotherapy Plus Concomitant and Adjuvant Temozolomide.
    World neurosurgery, 2017, Volume: 97

    Topics: Adult; Age Factors; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant

2017
Permeability Surface Area Product Using Perfusion Computed Tomography Is a Valuable Prognostic Factor in Glioblastomas Treated with Radiotherapy Plus Concomitant and Adjuvant Temozolomide.
    World neurosurgery, 2017, Volume: 97

    Topics: Adult; Age Factors; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant

2017
Permeability Surface Area Product Using Perfusion Computed Tomography Is a Valuable Prognostic Factor in Glioblastomas Treated with Radiotherapy Plus Concomitant and Adjuvant Temozolomide.
    World neurosurgery, 2017, Volume: 97

    Topics: Adult; Age Factors; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant

2017
Inhibition of carbonic anhydrase IX in glioblastoma multiforme.
    European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 2016, Volume: 109

    Topics: Acetazolamide; Antineoplastic Agents; Brain Neoplasms; Carbonic Anhydrase Inhibitors; Carbonic Anhyd

2016
Inhibition of carbonic anhydrase IX in glioblastoma multiforme.
    European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 2016, Volume: 109

    Topics: Acetazolamide; Antineoplastic Agents; Brain Neoplasms; Carbonic Anhydrase Inhibitors; Carbonic Anhyd

2016
Inhibition of carbonic anhydrase IX in glioblastoma multiforme.
    European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 2016, Volume: 109

    Topics: Acetazolamide; Antineoplastic Agents; Brain Neoplasms; Carbonic Anhydrase Inhibitors; Carbonic Anhyd

2016
Analysis of expression and prognostic significance of vimentin and the response to temozolomide in glioma patients.
    Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine, 2016, Volume: 37, Issue:11

    Topics: Adult; Antineoplastic Agents, Alkylating; Biomarkers, Tumor; Brain Neoplasms; Dacarbazine; Female; F

2016
Analysis of expression and prognostic significance of vimentin and the response to temozolomide in glioma patients.
    Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine, 2016, Volume: 37, Issue:11

    Topics: Adult; Antineoplastic Agents, Alkylating; Biomarkers, Tumor; Brain Neoplasms; Dacarbazine; Female; F

2016
Analysis of expression and prognostic significance of vimentin and the response to temozolomide in glioma patients.
    Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine, 2016, Volume: 37, Issue:11

    Topics: Adult; Antineoplastic Agents, Alkylating; Biomarkers, Tumor; Brain Neoplasms; Dacarbazine; Female; F

2016
Reciprocal regulation of the cholinic phenotype and epithelial-mesenchymal transition in glioblastoma cells.
    Oncotarget, 2016, Nov-08, Volume: 7, Issue:45

    Topics: Brain Neoplasms; Cell Line, Tumor; Cell Survival; Choline; Choline Kinase; Dacarbazine; Energy Metab

2016
Reciprocal regulation of the cholinic phenotype and epithelial-mesenchymal transition in glioblastoma cells.
    Oncotarget, 2016, Nov-08, Volume: 7, Issue:45

    Topics: Brain Neoplasms; Cell Line, Tumor; Cell Survival; Choline; Choline Kinase; Dacarbazine; Energy Metab

2016
Reciprocal regulation of the cholinic phenotype and epithelial-mesenchymal transition in glioblastoma cells.
    Oncotarget, 2016, Nov-08, Volume: 7, Issue:45

    Topics: Brain Neoplasms; Cell Line, Tumor; Cell Survival; Choline; Choline Kinase; Dacarbazine; Energy Metab

2016
MiRNA203 suppresses the expression of protumorigenic STAT1 in glioblastoma to inhibit tumorigenesis.
    Oncotarget, 2016, Dec-20, Volume: 7, Issue:51

    Topics: Animals; Antineoplastic Agents; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cell Movement; Cell Pr

2016
MiRNA203 suppresses the expression of protumorigenic STAT1 in glioblastoma to inhibit tumorigenesis.
    Oncotarget, 2016, Dec-20, Volume: 7, Issue:51

    Topics: Animals; Antineoplastic Agents; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cell Movement; Cell Pr

2016
MiRNA203 suppresses the expression of protumorigenic STAT1 in glioblastoma to inhibit tumorigenesis.
    Oncotarget, 2016, Dec-20, Volume: 7, Issue:51

    Topics: Animals; Antineoplastic Agents; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cell Movement; Cell Pr

2016
3D bioprinted glioma stem cells for brain tumor model and applications of drug susceptibility.
    Biofabrication, 2016, 10-11, Volume: 8, Issue:4

    Topics: Alginates; Antineoplastic Agents, Alkylating; Bioprinting; Brain Neoplasms; Cell Line, Tumor; Cell P

2016
3D bioprinted glioma stem cells for brain tumor model and applications of drug susceptibility.
    Biofabrication, 2016, 10-11, Volume: 8, Issue:4

    Topics: Alginates; Antineoplastic Agents, Alkylating; Bioprinting; Brain Neoplasms; Cell Line, Tumor; Cell P

2016
3D bioprinted glioma stem cells for brain tumor model and applications of drug susceptibility.
    Biofabrication, 2016, 10-11, Volume: 8, Issue:4

    Topics: Alginates; Antineoplastic Agents, Alkylating; Bioprinting; Brain Neoplasms; Cell Line, Tumor; Cell P

2016
Bone marrow response as a potential biomarker of outcomes in glioblastoma patients.
    Journal of neurosurgery, 2017, Volume: 127, Issue:1

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Bone Marrow; Brain Ne

2017
Bone marrow response as a potential biomarker of outcomes in glioblastoma patients.
    Journal of neurosurgery, 2017, Volume: 127, Issue:1

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Bone Marrow; Brain Ne

2017
Bone marrow response as a potential biomarker of outcomes in glioblastoma patients.
    Journal of neurosurgery, 2017, Volume: 127, Issue:1

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Bone Marrow; Brain Ne

2017
IDH mutation and MGMT promoter methylation are associated with the pseudoprogression and improved prognosis of glioblastoma multiforme patients who have undergone concurrent and adjuvant temozolomide-based chemoradiotherapy.
    Clinical neurology and neurosurgery, 2016, Volume: 151

    Topics: Adult; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy, Adjuvant; Dacarbazine;

2016
IDH mutation and MGMT promoter methylation are associated with the pseudoprogression and improved prognosis of glioblastoma multiforme patients who have undergone concurrent and adjuvant temozolomide-based chemoradiotherapy.
    Clinical neurology and neurosurgery, 2016, Volume: 151

    Topics: Adult; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy, Adjuvant; Dacarbazine;

2016
IDH mutation and MGMT promoter methylation are associated with the pseudoprogression and improved prognosis of glioblastoma multiforme patients who have undergone concurrent and adjuvant temozolomide-based chemoradiotherapy.
    Clinical neurology and neurosurgery, 2016, Volume: 151

    Topics: Adult; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy, Adjuvant; Dacarbazine;

2016
Comparative effectiveness of radiotherapy with vs. without temozolomide in older patients with glioblastoma.
    Journal of neuro-oncology, 2017, Volume: 131, Issue:2

    Topics: Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cohort Studies; Combine

2017
Comparative effectiveness of radiotherapy with vs. without temozolomide in older patients with glioblastoma.
    Journal of neuro-oncology, 2017, Volume: 131, Issue:2

    Topics: Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cohort Studies; Combine

2017
Comparative effectiveness of radiotherapy with vs. without temozolomide in older patients with glioblastoma.
    Journal of neuro-oncology, 2017, Volume: 131, Issue:2

    Topics: Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cohort Studies; Combine

2017
Metformin treatment reduces temozolomide resistance of glioblastoma cells.
    Oncotarget, 2016, Nov-29, Volume: 7, Issue:48

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Cell Line, Tumor; Cell Mov

2016
Metformin treatment reduces temozolomide resistance of glioblastoma cells.
    Oncotarget, 2016, Nov-29, Volume: 7, Issue:48

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Cell Line, Tumor; Cell Mov

2016
Metformin treatment reduces temozolomide resistance of glioblastoma cells.
    Oncotarget, 2016, Nov-29, Volume: 7, Issue:48

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Cell Line, Tumor; Cell Mov

2016
MicroRNA-101 reverses temozolomide resistance by inhibition of GSK3β in glioblastoma.
    Oncotarget, 2016, Nov-29, Volume: 7, Issue:48

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Dacarbazine; DNA Meth

2016
MicroRNA-101 reverses temozolomide resistance by inhibition of GSK3β in glioblastoma.
    Oncotarget, 2016, Nov-29, Volume: 7, Issue:48

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Dacarbazine; DNA Meth

2016
MicroRNA-101 reverses temozolomide resistance by inhibition of GSK3β in glioblastoma.
    Oncotarget, 2016, Nov-29, Volume: 7, Issue:48

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Dacarbazine; DNA Meth

2016
DNA Repair Capacity in Multiple Pathways Predicts Chemoresistance in Glioblastoma Multiforme.
    Cancer research, 2017, 01-01, Volume: 77, Issue:1

    Topics: Animals; Antineoplastic Agents; Area Under Curve; Brain Neoplasms; Cell Line, Tumor; Dacarbazine; DN

2017
DNA Repair Capacity in Multiple Pathways Predicts Chemoresistance in Glioblastoma Multiforme.
    Cancer research, 2017, 01-01, Volume: 77, Issue:1

    Topics: Animals; Antineoplastic Agents; Area Under Curve; Brain Neoplasms; Cell Line, Tumor; Dacarbazine; DN

2017
DNA Repair Capacity in Multiple Pathways Predicts Chemoresistance in Glioblastoma Multiforme.
    Cancer research, 2017, 01-01, Volume: 77, Issue:1

    Topics: Animals; Antineoplastic Agents; Area Under Curve; Brain Neoplasms; Cell Line, Tumor; Dacarbazine; DN

2017
Silencing of histone deacetylase 2 suppresses malignancy for proliferation, migration, and invasion of glioblastoma cells and enhances temozolomide sensitivity.
    Cancer chemotherapy and pharmacology, 2016, Volume: 78, Issue:6

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Cell Movement; Cell Proliferat

2016
Silencing of histone deacetylase 2 suppresses malignancy for proliferation, migration, and invasion of glioblastoma cells and enhances temozolomide sensitivity.
    Cancer chemotherapy and pharmacology, 2016, Volume: 78, Issue:6

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Cell Movement; Cell Proliferat

2016
Silencing of histone deacetylase 2 suppresses malignancy for proliferation, migration, and invasion of glioblastoma cells and enhances temozolomide sensitivity.
    Cancer chemotherapy and pharmacology, 2016, Volume: 78, Issue:6

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Cell Movement; Cell Proliferat

2016
MR Imaging Analysis of Non-Measurable Enhancing Lesions Newly Appearing after Concomitant Chemoradiotherapy in Glioblastoma Patients for Prognosis Prediction.
    PloS one, 2016, Volume: 11, Issue:11

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Dacarbazine; Dis

2016
MR Imaging Analysis of Non-Measurable Enhancing Lesions Newly Appearing after Concomitant Chemoradiotherapy in Glioblastoma Patients for Prognosis Prediction.
    PloS one, 2016, Volume: 11, Issue:11

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Dacarbazine; Dis

2016
MR Imaging Analysis of Non-Measurable Enhancing Lesions Newly Appearing after Concomitant Chemoradiotherapy in Glioblastoma Patients for Prognosis Prediction.
    PloS one, 2016, Volume: 11, Issue:11

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Dacarbazine; Dis

2016
Exosomal miR-221 targets DNM3 to induce tumor progression and temozolomide resistance in glioma.
    Journal of neuro-oncology, 2017, Volume: 131, Issue:2

    Topics: Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation;

2017
Exosomal miR-221 targets DNM3 to induce tumor progression and temozolomide resistance in glioma.
    Journal of neuro-oncology, 2017, Volume: 131, Issue:2

    Topics: Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation;

2017
Exosomal miR-221 targets DNM3 to induce tumor progression and temozolomide resistance in glioma.
    Journal of neuro-oncology, 2017, Volume: 131, Issue:2

    Topics: Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation;

2017
Temozolomide inhibits cellular growth and motility via targeting ERK signaling in glioma C6 cells.
    Molecular medicine reports, 2016, Volume: 14, Issue:6

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Transformed; Cell Line, Tumo

2016
Temozolomide inhibits cellular growth and motility via targeting ERK signaling in glioma C6 cells.
    Molecular medicine reports, 2016, Volume: 14, Issue:6

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Transformed; Cell Line, Tumo

2016
Temozolomide inhibits cellular growth and motility via targeting ERK signaling in glioma C6 cells.
    Molecular medicine reports, 2016, Volume: 14, Issue:6

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Transformed; Cell Line, Tumo

2016
Prognostic relevance of miRNA-155 methylation in anaplastic glioma.
    Oncotarget, 2016, Dec-13, Volume: 7, Issue:50

    Topics: Antineoplastic Agents, Alkylating; Biomarkers, Tumor; Brain Neoplasms; Cell Line, Tumor; Dacarbazine

2016
Prognostic relevance of miRNA-155 methylation in anaplastic glioma.
    Oncotarget, 2016, Dec-13, Volume: 7, Issue:50

    Topics: Antineoplastic Agents, Alkylating; Biomarkers, Tumor; Brain Neoplasms; Cell Line, Tumor; Dacarbazine

2016
Prognostic relevance of miRNA-155 methylation in anaplastic glioma.
    Oncotarget, 2016, Dec-13, Volume: 7, Issue:50

    Topics: Antineoplastic Agents, Alkylating; Biomarkers, Tumor; Brain Neoplasms; Cell Line, Tumor; Dacarbazine

2016
Cutaneous invasive aspergillosis in a patient with glioblastoma receiving long-term temozolomide and corticosteroid therapy.
    Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy, 2017, Volume: 23, Issue:4

    Topics: Adrenal Cortex Hormones; Aged; Aspergillosis; Brain Neoplasms; Combined Modality Therapy; Dacarbazin

2017
Cutaneous invasive aspergillosis in a patient with glioblastoma receiving long-term temozolomide and corticosteroid therapy.
    Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy, 2017, Volume: 23, Issue:4

    Topics: Adrenal Cortex Hormones; Aged; Aspergillosis; Brain Neoplasms; Combined Modality Therapy; Dacarbazin

2017
Cutaneous invasive aspergillosis in a patient with glioblastoma receiving long-term temozolomide and corticosteroid therapy.
    Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy, 2017, Volume: 23, Issue:4

    Topics: Adrenal Cortex Hormones; Aged; Aspergillosis; Brain Neoplasms; Combined Modality Therapy; Dacarbazin

2017
Valproic acid reduces hair loss and improves survival in patients receiving temozolomide-based radiation therapy for high-grade glioma.
    European journal of clinical pharmacology, 2017, Volume: 73, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Alopecia; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemor

2017
Valproic acid reduces hair loss and improves survival in patients receiving temozolomide-based radiation therapy for high-grade glioma.
    European journal of clinical pharmacology, 2017, Volume: 73, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Alopecia; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemor

2017
Valproic acid reduces hair loss and improves survival in patients receiving temozolomide-based radiation therapy for high-grade glioma.
    European journal of clinical pharmacology, 2017, Volume: 73, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Alopecia; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemor

2017
Silver nanoparticles enhance the sensitivity of temozolomide on human glioma cells.
    Oncotarget, 2017, Jan-31, Volume: 8, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Brain

2017
Silver nanoparticles enhance the sensitivity of temozolomide on human glioma cells.
    Oncotarget, 2017, Jan-31, Volume: 8, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Brain

2017
Silver nanoparticles enhance the sensitivity of temozolomide on human glioma cells.
    Oncotarget, 2017, Jan-31, Volume: 8, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Brain

2017
The Inhibition of microRNA-128 on IGF-1-Activating mTOR Signaling Involves in Temozolomide-Induced Glioma Cell Apoptotic Death.
    PloS one, 2016, Volume: 11, Issue:11

    Topics: Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Dacarbazine; Glioma; Humans; Insulin-

2016
The Inhibition of microRNA-128 on IGF-1-Activating mTOR Signaling Involves in Temozolomide-Induced Glioma Cell Apoptotic Death.
    PloS one, 2016, Volume: 11, Issue:11

    Topics: Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Dacarbazine; Glioma; Humans; Insulin-

2016
The Inhibition of microRNA-128 on IGF-1-Activating mTOR Signaling Involves in Temozolomide-Induced Glioma Cell Apoptotic Death.
    PloS one, 2016, Volume: 11, Issue:11

    Topics: Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Dacarbazine; Glioma; Humans; Insulin-

2016
GANT61, a GLI inhibitor, sensitizes glioma cells to the temozolomide treatment.
    Journal of experimental & clinical cancer research : CR, 2016, 11-28, Volume: 35, Issue:1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Cell Line, Tumor; Cell Movement; Ce

2016
GANT61, a GLI inhibitor, sensitizes glioma cells to the temozolomide treatment.
    Journal of experimental & clinical cancer research : CR, 2016, 11-28, Volume: 35, Issue:1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Cell Line, Tumor; Cell Movement; Ce

2016
GANT61, a GLI inhibitor, sensitizes glioma cells to the temozolomide treatment.
    Journal of experimental & clinical cancer research : CR, 2016, 11-28, Volume: 35, Issue:1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Cell Line, Tumor; Cell Movement; Ce

2016
MiR-433-3p suppresses cell growth and enhances chemosensitivity by targeting CREB in human glioma.
    Oncotarget, 2017, Jan-17, Volume: 8, Issue:3

    Topics: 3' Untranslated Regions; Adult; Brain Neoplasms; Cell Line, Tumor; Cell Movement; Cell Proliferation

2017
MiR-433-3p suppresses cell growth and enhances chemosensitivity by targeting CREB in human glioma.
    Oncotarget, 2017, Jan-17, Volume: 8, Issue:3

    Topics: 3' Untranslated Regions; Adult; Brain Neoplasms; Cell Line, Tumor; Cell Movement; Cell Proliferation

2017
MiR-433-3p suppresses cell growth and enhances chemosensitivity by targeting CREB in human glioma.
    Oncotarget, 2017, Jan-17, Volume: 8, Issue:3

    Topics: 3' Untranslated Regions; Adult; Brain Neoplasms; Cell Line, Tumor; Cell Movement; Cell Proliferation

2017
pH-Sensitive O6-Benzylguanosine Polymer Modified Magnetic Nanoparticles for Treatment of Glioblastomas.
    Bioconjugate chemistry, 2017, 01-18, Volume: 28, Issue:1

    Topics: Brain Neoplasms; Cell Line, Tumor; Dacarbazine; Glioblastoma; Guanosine; Humans; Hydrogen-Ion Concen

2017
pH-Sensitive O6-Benzylguanosine Polymer Modified Magnetic Nanoparticles for Treatment of Glioblastomas.
    Bioconjugate chemistry, 2017, 01-18, Volume: 28, Issue:1

    Topics: Brain Neoplasms; Cell Line, Tumor; Dacarbazine; Glioblastoma; Guanosine; Humans; Hydrogen-Ion Concen

2017
pH-Sensitive O6-Benzylguanosine Polymer Modified Magnetic Nanoparticles for Treatment of Glioblastomas.
    Bioconjugate chemistry, 2017, 01-18, Volume: 28, Issue:1

    Topics: Brain Neoplasms; Cell Line, Tumor; Dacarbazine; Glioblastoma; Guanosine; Humans; Hydrogen-Ion Concen

2017
Use of an anti-viral drug, Ribavirin, as an anti-glioblastoma therapeutic.
    Oncogene, 2017, 05-25, Volume: 36, Issue:21

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Antiviral Agents; Brain Neoplasms; Cell Lin

2017
Use of an anti-viral drug, Ribavirin, as an anti-glioblastoma therapeutic.
    Oncogene, 2017, 05-25, Volume: 36, Issue:21

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Antiviral Agents; Brain Neoplasms; Cell Lin

2017
Use of an anti-viral drug, Ribavirin, as an anti-glioblastoma therapeutic.
    Oncogene, 2017, 05-25, Volume: 36, Issue:21

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Antiviral Agents; Brain Neoplasms; Cell Lin

2017
Immune modulation associated with vascular endothelial growth factor (VEGF) blockade in patients with glioblastoma.
    Cancer immunology, immunotherapy : CII, 2017, Volume: 66, Issue:3

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Brain Neoplasms; Chemoradiotherap

2017
Immune modulation associated with vascular endothelial growth factor (VEGF) blockade in patients with glioblastoma.
    Cancer immunology, immunotherapy : CII, 2017, Volume: 66, Issue:3

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Brain Neoplasms; Chemoradiotherap

2017
Immune modulation associated with vascular endothelial growth factor (VEGF) blockade in patients with glioblastoma.
    Cancer immunology, immunotherapy : CII, 2017, Volume: 66, Issue:3

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Brain Neoplasms; Chemoradiotherap

2017
Case 38-2016. A 52-Year-Old Woman with Recurrent Oligodendroglioma.
    The New England journal of medicine, 2016, 12-15, Volume: 375, Issue:24

    Topics: Antineoplastic Agents, Alkylating; Biopsy; Brain Neoplasms; Chemotherapy, Adjuvant; Dacarbazine; Dia

2016
Case 38-2016. A 52-Year-Old Woman with Recurrent Oligodendroglioma.
    The New England journal of medicine, 2016, 12-15, Volume: 375, Issue:24

    Topics: Antineoplastic Agents, Alkylating; Biopsy; Brain Neoplasms; Chemotherapy, Adjuvant; Dacarbazine; Dia

2016
Case 38-2016. A 52-Year-Old Woman with Recurrent Oligodendroglioma.
    The New England journal of medicine, 2016, 12-15, Volume: 375, Issue:24

    Topics: Antineoplastic Agents, Alkylating; Biopsy; Brain Neoplasms; Chemotherapy, Adjuvant; Dacarbazine; Dia

2016
Pathological characterization of nivolumab-related liver injury in a patient with glioblastoma.
    Immunotherapy, 2016, Volume: 8, Issue:12

    Topics: Aged; Antibodies, Monoclonal; Antineoplastic Agents; Autoimmunity; Brain Neoplasms; Chemical and Dru

2016
Pathological characterization of nivolumab-related liver injury in a patient with glioblastoma.
    Immunotherapy, 2016, Volume: 8, Issue:12

    Topics: Aged; Antibodies, Monoclonal; Antineoplastic Agents; Autoimmunity; Brain Neoplasms; Chemical and Dru

2016
Pathological characterization of nivolumab-related liver injury in a patient with glioblastoma.
    Immunotherapy, 2016, Volume: 8, Issue:12

    Topics: Aged; Antibodies, Monoclonal; Antineoplastic Agents; Autoimmunity; Brain Neoplasms; Chemical and Dru

2016
Regression of a glioblastoma multiforme: spontaneous versus a potential antineoplastic effect of dexamethasone and levetiracetam.
    BMJ case reports, 2016, Dec-23, Volume: 2016

    Topics: Antineoplastic Combined Chemotherapy Protocols; Astrocytoma; Brain Neoplasms; Cognition Disorders; D

2016
Regression of a glioblastoma multiforme: spontaneous versus a potential antineoplastic effect of dexamethasone and levetiracetam.
    BMJ case reports, 2016, Dec-23, Volume: 2016

    Topics: Antineoplastic Combined Chemotherapy Protocols; Astrocytoma; Brain Neoplasms; Cognition Disorders; D

2016
Regression of a glioblastoma multiforme: spontaneous versus a potential antineoplastic effect of dexamethasone and levetiracetam.
    BMJ case reports, 2016, Dec-23, Volume: 2016

    Topics: Antineoplastic Combined Chemotherapy Protocols; Astrocytoma; Brain Neoplasms; Cognition Disorders; D

2016
Prognostic parameters and outcome after re-irradiation for progressive glioblastoma.
    Acta neurologica Scandinavica, 2017, Volume: 136, Issue:3

    Topics: Adult; Aged; Brain Neoplasms; Dacarbazine; Female; Glioblastoma; Humans; Male; Middle Aged; Radiosur

2017
Prognostic parameters and outcome after re-irradiation for progressive glioblastoma.
    Acta neurologica Scandinavica, 2017, Volume: 136, Issue:3

    Topics: Adult; Aged; Brain Neoplasms; Dacarbazine; Female; Glioblastoma; Humans; Male; Middle Aged; Radiosur

2017
Prognostic parameters and outcome after re-irradiation for progressive glioblastoma.
    Acta neurologica Scandinavica, 2017, Volume: 136, Issue:3

    Topics: Adult; Aged; Brain Neoplasms; Dacarbazine; Female; Glioblastoma; Humans; Male; Middle Aged; Radiosur

2017
Comments regarding "Hepatotoxicity by combination treatment of temozolomide, artesunate and Chinese herbs in a glioblastoma multiforme patient: case report review of the literature".
    Archives of toxicology, 2017, Volume: 91, Issue:6

    Topics: Artemisinins; Artesunate; Brain Neoplasms; Chemical and Drug Induced Liver Injury; Dacarbazine; Glio

2017
Comments regarding "Hepatotoxicity by combination treatment of temozolomide, artesunate and Chinese herbs in a glioblastoma multiforme patient: case report review of the literature".
    Archives of toxicology, 2017, Volume: 91, Issue:6

    Topics: Artemisinins; Artesunate; Brain Neoplasms; Chemical and Drug Induced Liver Injury; Dacarbazine; Glio

2017
Comments regarding "Hepatotoxicity by combination treatment of temozolomide, artesunate and Chinese herbs in a glioblastoma multiforme patient: case report review of the literature".
    Archives of toxicology, 2017, Volume: 91, Issue:6

    Topics: Artemisinins; Artesunate; Brain Neoplasms; Chemical and Drug Induced Liver Injury; Dacarbazine; Glio

2017
Acute liver injury induced by levetiracetam and temozolomide co-treatment.
    Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver, 2017, Volume: 49, Issue:3

    Topics: Adult; Aged; Anticonvulsants; Antineoplastic Agents, Alkylating; Brain Neoplasms; Case-Control Studi

2017
Acute liver injury induced by levetiracetam and temozolomide co-treatment.
    Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver, 2017, Volume: 49, Issue:3

    Topics: Adult; Aged; Anticonvulsants; Antineoplastic Agents, Alkylating; Brain Neoplasms; Case-Control Studi

2017
Acute liver injury induced by levetiracetam and temozolomide co-treatment.
    Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver, 2017, Volume: 49, Issue:3

    Topics: Adult; Aged; Anticonvulsants; Antineoplastic Agents, Alkylating; Brain Neoplasms; Case-Control Studi

2017
Role of miR-223/paired box 6 signaling in temozolomide chemoresistance in glioblastoma multiforme cells.
    Molecular medicine reports, 2017, Volume: 15, Issue:2

    Topics: 3' Untranslated Regions; Antagomirs; Antineoplastic Agents, Alkylating; Base Sequence; Brain Neoplas

2017
Role of miR-223/paired box 6 signaling in temozolomide chemoresistance in glioblastoma multiforme cells.
    Molecular medicine reports, 2017, Volume: 15, Issue:2

    Topics: 3' Untranslated Regions; Antagomirs; Antineoplastic Agents, Alkylating; Base Sequence; Brain Neoplas

2017
Role of miR-223/paired box 6 signaling in temozolomide chemoresistance in glioblastoma multiforme cells.
    Molecular medicine reports, 2017, Volume: 15, Issue:2

    Topics: 3' Untranslated Regions; Antagomirs; Antineoplastic Agents, Alkylating; Base Sequence; Brain Neoplas

2017
Up-regulation of miR-497 confers resistance to temozolomide in human glioma cells by targeting mTOR/Bcl-2.
    Cancer medicine, 2017, Volume: 6, Issue:2

    Topics: 3' Untranslated Regions; Animals; Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cel

2017
Up-regulation of miR-497 confers resistance to temozolomide in human glioma cells by targeting mTOR/Bcl-2.
    Cancer medicine, 2017, Volume: 6, Issue:2

    Topics: 3' Untranslated Regions; Animals; Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cel

2017
Up-regulation of miR-497 confers resistance to temozolomide in human glioma cells by targeting mTOR/Bcl-2.
    Cancer medicine, 2017, Volume: 6, Issue:2

    Topics: 3' Untranslated Regions; Animals; Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cel

2017
The efficacy and roles of combining temozolomide with whole brain radiotherapy in protection neurocognitive function and improvement quality of life of non-small-cell lung cancer patients with brain metastases.
    BMC cancer, 2017, 01-10, Volume: 17, Issue:1

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms;

2017
The efficacy and roles of combining temozolomide with whole brain radiotherapy in protection neurocognitive function and improvement quality of life of non-small-cell lung cancer patients with brain metastases.
    BMC cancer, 2017, 01-10, Volume: 17, Issue:1

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms;

2017
The efficacy and roles of combining temozolomide with whole brain radiotherapy in protection neurocognitive function and improvement quality of life of non-small-cell lung cancer patients with brain metastases.
    BMC cancer, 2017, 01-10, Volume: 17, Issue:1

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms;

2017
Mesenchymal subtype of glioblastomas with high DNA-PKcs expression is associated with better response to radiotherapy and temozolomide.
    Journal of neuro-oncology, 2017, Volume: 132, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; DNA

2017
Mesenchymal subtype of glioblastomas with high DNA-PKcs expression is associated with better response to radiotherapy and temozolomide.
    Journal of neuro-oncology, 2017, Volume: 132, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; DNA

2017
Mesenchymal subtype of glioblastomas with high DNA-PKcs expression is associated with better response to radiotherapy and temozolomide.
    Journal of neuro-oncology, 2017, Volume: 132, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; DNA

2017
Identification of aurintricarboxylic acid as a selective inhibitor of the TWEAK-Fn14 signaling pathway in glioblastoma cells.
    Oncotarget, 2017, Feb-14, Volume: 8, Issue:7

    Topics: Animals; Antineoplastic Agents, Alkylating; Aurintricarboxylic Acid; Brain Neoplasms; Cell Line, Tum

2017
Identification of aurintricarboxylic acid as a selective inhibitor of the TWEAK-Fn14 signaling pathway in glioblastoma cells.
    Oncotarget, 2017, Feb-14, Volume: 8, Issue:7

    Topics: Animals; Antineoplastic Agents, Alkylating; Aurintricarboxylic Acid; Brain Neoplasms; Cell Line, Tum

2017
Identification of aurintricarboxylic acid as a selective inhibitor of the TWEAK-Fn14 signaling pathway in glioblastoma cells.
    Oncotarget, 2017, Feb-14, Volume: 8, Issue:7

    Topics: Animals; Antineoplastic Agents, Alkylating; Aurintricarboxylic Acid; Brain Neoplasms; Cell Line, Tum

2017
Overexpression of ILK promotes temozolomide resistance in glioma cells.
    Molecular medicine reports, 2017, Volume: 15, Issue:3

    Topics: Antineoplastic Agents, Alkylating; bcl-2-Associated X Protein; Brain Neoplasms; Caspase 3; Cell Line

2017
Overexpression of ILK promotes temozolomide resistance in glioma cells.
    Molecular medicine reports, 2017, Volume: 15, Issue:3

    Topics: Antineoplastic Agents, Alkylating; bcl-2-Associated X Protein; Brain Neoplasms; Caspase 3; Cell Line

2017
Overexpression of ILK promotes temozolomide resistance in glioma cells.
    Molecular medicine reports, 2017, Volume: 15, Issue:3

    Topics: Antineoplastic Agents, Alkylating; bcl-2-Associated X Protein; Brain Neoplasms; Caspase 3; Cell Line

2017
The PI3K inhibitor GDC-0941 enhances radiosensitization and reduces chemoresistance to temozolomide in GBM cell lines.
    Neuroscience, 2017, 03-27, Volume: 346

    Topics: Antineoplastic Agents; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Proto

2017
The PI3K inhibitor GDC-0941 enhances radiosensitization and reduces chemoresistance to temozolomide in GBM cell lines.
    Neuroscience, 2017, 03-27, Volume: 346

    Topics: Antineoplastic Agents; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Proto

2017
The PI3K inhibitor GDC-0941 enhances radiosensitization and reduces chemoresistance to temozolomide in GBM cell lines.
    Neuroscience, 2017, 03-27, Volume: 346

    Topics: Antineoplastic Agents; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Proto

2017
Impact of Including Peritumoral Edema in Radiotherapy Target Volume on Patterns of Failure in Glioblastoma following Temozolomide-based Chemoradiotherapy.
    Scientific reports, 2017, 02-08, Volume: 7

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Edema; Brain Neoplasms; Chemoradiotherapy; Coh

2017
Impact of Including Peritumoral Edema in Radiotherapy Target Volume on Patterns of Failure in Glioblastoma following Temozolomide-based Chemoradiotherapy.
    Scientific reports, 2017, 02-08, Volume: 7

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Edema; Brain Neoplasms; Chemoradiotherapy; Coh

2017
Impact of Including Peritumoral Edema in Radiotherapy Target Volume on Patterns of Failure in Glioblastoma following Temozolomide-based Chemoradiotherapy.
    Scientific reports, 2017, 02-08, Volume: 7

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Edema; Brain Neoplasms; Chemoradiotherapy; Coh

2017
DNA-Targeted Inhibition of MGMT.
    Chembiochem : a European journal of chemical biology, 2017, 05-18, Volume: 18, Issue:10

    Topics: Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Dacarbazine; DNA; DNA Modification Me

2017
DNA-Targeted Inhibition of MGMT.
    Chembiochem : a European journal of chemical biology, 2017, 05-18, Volume: 18, Issue:10

    Topics: Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Dacarbazine; DNA; DNA Modification Me

2017
DNA-Targeted Inhibition of MGMT.
    Chembiochem : a European journal of chemical biology, 2017, 05-18, Volume: 18, Issue:10

    Topics: Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Dacarbazine; DNA; DNA Modification Me

2017
Atorvastatin Promotes Cytotoxicity and Reduces Migration and Proliferation of Human A172 Glioma Cells.
    Molecular neurobiology, 2018, Volume: 55, Issue:2

    Topics: Antineoplastic Agents, Alkylating; Apoptosis; Atorvastatin; Autophagy; Brain Neoplasms; Cell Line, T

2018
Atorvastatin Promotes Cytotoxicity and Reduces Migration and Proliferation of Human A172 Glioma Cells.
    Molecular neurobiology, 2018, Volume: 55, Issue:2

    Topics: Antineoplastic Agents, Alkylating; Apoptosis; Atorvastatin; Autophagy; Brain Neoplasms; Cell Line, T

2018
Atorvastatin Promotes Cytotoxicity and Reduces Migration and Proliferation of Human A172 Glioma Cells.
    Molecular neurobiology, 2018, Volume: 55, Issue:2

    Topics: Antineoplastic Agents, Alkylating; Apoptosis; Atorvastatin; Autophagy; Brain Neoplasms; Cell Line, T

2018
FoxM1-mediated RFC5 expression promotes temozolomide resistance.
    Cell biology and toxicology, 2017, Volume: 33, Issue:6

    Topics: Brain Neoplasms; Cell Line, Tumor; Dacarbazine; DNA Repair; Drug Resistance, Neoplasm; Forkhead Box

2017
FoxM1-mediated RFC5 expression promotes temozolomide resistance.
    Cell biology and toxicology, 2017, Volume: 33, Issue:6

    Topics: Brain Neoplasms; Cell Line, Tumor; Dacarbazine; DNA Repair; Drug Resistance, Neoplasm; Forkhead Box

2017
FoxM1-mediated RFC5 expression promotes temozolomide resistance.
    Cell biology and toxicology, 2017, Volume: 33, Issue:6

    Topics: Brain Neoplasms; Cell Line, Tumor; Dacarbazine; DNA Repair; Drug Resistance, Neoplasm; Forkhead Box

2017
MALAT1 is a prognostic factor in glioblastoma multiforme and induces chemoresistance to temozolomide through suppressing miR-203 and promoting thymidylate synthase expression.
    Oncotarget, 2017, Apr-04, Volume: 8, Issue:14

    Topics: Antineoplastic Agents, Alkylating; Apoptosis; Biomarkers, Tumor; Brain Neoplasms; Cell Cycle; Cell P

2017
MALAT1 is a prognostic factor in glioblastoma multiforme and induces chemoresistance to temozolomide through suppressing miR-203 and promoting thymidylate synthase expression.
    Oncotarget, 2017, Apr-04, Volume: 8, Issue:14

    Topics: Antineoplastic Agents, Alkylating; Apoptosis; Biomarkers, Tumor; Brain Neoplasms; Cell Cycle; Cell P

2017
MALAT1 is a prognostic factor in glioblastoma multiforme and induces chemoresistance to temozolomide through suppressing miR-203 and promoting thymidylate synthase expression.
    Oncotarget, 2017, Apr-04, Volume: 8, Issue:14

    Topics: Antineoplastic Agents, Alkylating; Apoptosis; Biomarkers, Tumor; Brain Neoplasms; Cell Cycle; Cell P

2017
High-dose Neural Stem Cell Radiation May Not Improve Survival in Glioblastoma.
    Clinical oncology (Royal College of Radiologists (Great Britain)), 2017, Volume: 29, Issue:6

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy, Adjuvant; Contra

2017
High-dose Neural Stem Cell Radiation May Not Improve Survival in Glioblastoma.
    Clinical oncology (Royal College of Radiologists (Great Britain)), 2017, Volume: 29, Issue:6

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy, Adjuvant; Contra

2017
High-dose Neural Stem Cell Radiation May Not Improve Survival in Glioblastoma.
    Clinical oncology (Royal College of Radiologists (Great Britain)), 2017, Volume: 29, Issue:6

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy, Adjuvant; Contra

2017
The Effect of Ascorbic Acid over the Etoposide- and Temozolomide-Mediated Cytotoxicity in Glioblastoma Cell Culture: A Molecular Study.
    Turkish neurosurgery, 2018, Volume: 28, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Ascorbic Acid; Br

2018
The Effect of Ascorbic Acid over the Etoposide- and Temozolomide-Mediated Cytotoxicity in Glioblastoma Cell Culture: A Molecular Study.
    Turkish neurosurgery, 2018, Volume: 28, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Ascorbic Acid; Br

2018
The Effect of Ascorbic Acid over the Etoposide- and Temozolomide-Mediated Cytotoxicity in Glioblastoma Cell Culture: A Molecular Study.
    Turkish neurosurgery, 2018, Volume: 28, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Ascorbic Acid; Br

2018
Temozolomide during radiotherapy of glioblastoma multiforme : Daily administration improves survival.
    Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 2017, Volume: 193, Issue:11

    Topics: Adult; Aged; Brain Neoplasms; Chemoradiotherapy; Combined Modality Therapy; Dacarbazine; Dose-Respon

2017
Temozolomide during radiotherapy of glioblastoma multiforme : Daily administration improves survival.
    Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 2017, Volume: 193, Issue:11

    Topics: Adult; Aged; Brain Neoplasms; Chemoradiotherapy; Combined Modality Therapy; Dacarbazine; Dose-Respon

2017
Temozolomide during radiotherapy of glioblastoma multiforme : Daily administration improves survival.
    Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 2017, Volume: 193, Issue:11

    Topics: Adult; Aged; Brain Neoplasms; Chemoradiotherapy; Combined Modality Therapy; Dacarbazine; Dose-Respon

2017
Chemosensitivity of IDH1-Mutated Gliomas Due to an Impairment in PARP1-Mediated DNA Repair.
    Cancer research, 2017, 04-01, Volume: 77, Issue:7

    Topics: Brain Neoplasms; Cell Line, Tumor; Dacarbazine; DNA Repair; Glioma; Humans; Isocitrate Dehydrogenase

2017
Chemosensitivity of IDH1-Mutated Gliomas Due to an Impairment in PARP1-Mediated DNA Repair.
    Cancer research, 2017, 04-01, Volume: 77, Issue:7

    Topics: Brain Neoplasms; Cell Line, Tumor; Dacarbazine; DNA Repair; Glioma; Humans; Isocitrate Dehydrogenase

2017
Chemosensitivity of IDH1-Mutated Gliomas Due to an Impairment in PARP1-Mediated DNA Repair.
    Cancer research, 2017, 04-01, Volume: 77, Issue:7

    Topics: Brain Neoplasms; Cell Line, Tumor; Dacarbazine; DNA Repair; Glioma; Humans; Isocitrate Dehydrogenase

2017
The clinical value of patient-derived glioblastoma tumorspheres in predicting treatment response.
    Neuro-oncology, 2017, Aug-01, Volume: 19, Issue:8

    Topics: Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Dacarbazine; Disease-Fr

2017
The clinical value of patient-derived glioblastoma tumorspheres in predicting treatment response.
    Neuro-oncology, 2017, Aug-01, Volume: 19, Issue:8

    Topics: Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Dacarbazine; Disease-Fr

2017
The clinical value of patient-derived glioblastoma tumorspheres in predicting treatment response.
    Neuro-oncology, 2017, Aug-01, Volume: 19, Issue:8

    Topics: Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Dacarbazine; Disease-Fr

2017
A mathematical model of low grade gliomas treated with temozolomide and its therapeutical implications.
    Mathematical biosciences, 2017, Volume: 288

    Topics: Brain Neoplasms; Cell Proliferation; Dacarbazine; Disease Progression; Female; Glioma; Humans; Male;

2017
A mathematical model of low grade gliomas treated with temozolomide and its therapeutical implications.
    Mathematical biosciences, 2017, Volume: 288

    Topics: Brain Neoplasms; Cell Proliferation; Dacarbazine; Disease Progression; Female; Glioma; Humans; Male;

2017
A mathematical model of low grade gliomas treated with temozolomide and its therapeutical implications.
    Mathematical biosciences, 2017, Volume: 288

    Topics: Brain Neoplasms; Cell Proliferation; Dacarbazine; Disease Progression; Female; Glioma; Humans; Male;

2017
miR-124 suppresses glioblastoma growth and potentiates chemosensitivity by inhibiting AURKA.
    Biochemical and biophysical research communications, 2017, 04-22, Volume: 486, Issue:1

    Topics: 3' Untranslated Regions; Aged; Antineoplastic Combined Chemotherapy Protocols; Aurora Kinase A; Azep

2017
miR-124 suppresses glioblastoma growth and potentiates chemosensitivity by inhibiting AURKA.
    Biochemical and biophysical research communications, 2017, 04-22, Volume: 486, Issue:1

    Topics: 3' Untranslated Regions; Aged; Antineoplastic Combined Chemotherapy Protocols; Aurora Kinase A; Azep

2017
miR-124 suppresses glioblastoma growth and potentiates chemosensitivity by inhibiting AURKA.
    Biochemical and biophysical research communications, 2017, 04-22, Volume: 486, Issue:1

    Topics: 3' Untranslated Regions; Aged; Antineoplastic Combined Chemotherapy Protocols; Aurora Kinase A; Azep

2017
FoxO3a induces temozolomide resistance in glioblastoma cells via the regulation of β-catenin nuclear accumulation.
    Oncology reports, 2017, Volume: 37, Issue:4

    Topics: Apoptosis; beta Catenin; Brain Neoplasms; Cell Line, Tumor; Cell Nucleus; Cell Proliferation; Dacarb

2017
FoxO3a induces temozolomide resistance in glioblastoma cells via the regulation of β-catenin nuclear accumulation.
    Oncology reports, 2017, Volume: 37, Issue:4

    Topics: Apoptosis; beta Catenin; Brain Neoplasms; Cell Line, Tumor; Cell Nucleus; Cell Proliferation; Dacarb

2017
FoxO3a induces temozolomide resistance in glioblastoma cells via the regulation of β-catenin nuclear accumulation.
    Oncology reports, 2017, Volume: 37, Issue:4

    Topics: Apoptosis; beta Catenin; Brain Neoplasms; Cell Line, Tumor; Cell Nucleus; Cell Proliferation; Dacarb

2017
Theranostic 3-Dimensional nano brain-implant for prolonged and localized treatment of recurrent glioma.
    Scientific reports, 2017, 03-06, Volume: 7

    Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Cell Line; Dacarbazine; Delayed-Action Preparations

2017
Theranostic 3-Dimensional nano brain-implant for prolonged and localized treatment of recurrent glioma.
    Scientific reports, 2017, 03-06, Volume: 7

    Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Cell Line; Dacarbazine; Delayed-Action Preparations

2017
Theranostic 3-Dimensional nano brain-implant for prolonged and localized treatment of recurrent glioma.
    Scientific reports, 2017, 03-06, Volume: 7

    Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Cell Line; Dacarbazine; Delayed-Action Preparations

2017
Predictive models for diffuse low-grade glioma patients under chemotherapy.
    Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference, 2016, Volume: 2016

    Topics: Brain Neoplasms; Dacarbazine; Databases, Factual; Glioma; Humans; Linear Models; Magnetic Resonance

2016
Predictive models for diffuse low-grade glioma patients under chemotherapy.
    Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference, 2016, Volume: 2016

    Topics: Brain Neoplasms; Dacarbazine; Databases, Factual; Glioma; Humans; Linear Models; Magnetic Resonance

2016
Predictive models for diffuse low-grade glioma patients under chemotherapy.
    Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference, 2016, Volume: 2016

    Topics: Brain Neoplasms; Dacarbazine; Databases, Factual; Glioma; Humans; Linear Models; Magnetic Resonance

2016
A Case of Therapy-Related Acute Myeloid Leukemia Associated with Adjuvant Temozolomide Chemotherapy for Anaplastic Astrocytoma.
    World neurosurgery, 2017, Volume: 101

    Topics: Adult; Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neoplasms; Chemotherapy, Adjuvant; Daca

2017
A Case of Therapy-Related Acute Myeloid Leukemia Associated with Adjuvant Temozolomide Chemotherapy for Anaplastic Astrocytoma.
    World neurosurgery, 2017, Volume: 101

    Topics: Adult; Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neoplasms; Chemotherapy, Adjuvant; Daca

2017
A Case of Therapy-Related Acute Myeloid Leukemia Associated with Adjuvant Temozolomide Chemotherapy for Anaplastic Astrocytoma.
    World neurosurgery, 2017, Volume: 101

    Topics: Adult; Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neoplasms; Chemotherapy, Adjuvant; Daca

2017
Rutin increases the cytotoxicity of temozolomide in glioblastoma via autophagy inhibition.
    Journal of neuro-oncology, 2017, Volume: 132, Issue:3

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Autophagy; Brain Neoplasms; Cell

2017
Rutin increases the cytotoxicity of temozolomide in glioblastoma via autophagy inhibition.
    Journal of neuro-oncology, 2017, Volume: 132, Issue:3

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Autophagy; Brain Neoplasms; Cell

2017
Rutin increases the cytotoxicity of temozolomide in glioblastoma via autophagy inhibition.
    Journal of neuro-oncology, 2017, Volume: 132, Issue:3

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Autophagy; Brain Neoplasms; Cell

2017
Limited role for extended maintenance temozolomide for newly diagnosed glioblastoma.
    Neurology, 2017, Apr-11, Volume: 88, Issue:15

    Topics: Adult; Age Factors; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cohort Studies; Dacarb

2017
Limited role for extended maintenance temozolomide for newly diagnosed glioblastoma.
    Neurology, 2017, Apr-11, Volume: 88, Issue:15

    Topics: Adult; Age Factors; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cohort Studies; Dacarb

2017
Limited role for extended maintenance temozolomide for newly diagnosed glioblastoma.
    Neurology, 2017, Apr-11, Volume: 88, Issue:15

    Topics: Adult; Age Factors; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cohort Studies; Dacarb

2017
Novel recursive partitioning analysis classification for newly diagnosed glioblastoma: A multi-institutional study highlighting the MGMT promoter methylation and IDH1 gene mutation status.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2017, Volume: 123, Issue:1

    Topics: Adult; Aged; Brain Neoplasms; Dacarbazine; DNA Methylation; DNA Modification Methylases; DNA Repair

2017
Novel recursive partitioning analysis classification for newly diagnosed glioblastoma: A multi-institutional study highlighting the MGMT promoter methylation and IDH1 gene mutation status.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2017, Volume: 123, Issue:1

    Topics: Adult; Aged; Brain Neoplasms; Dacarbazine; DNA Methylation; DNA Modification Methylases; DNA Repair

2017
Novel recursive partitioning analysis classification for newly diagnosed glioblastoma: A multi-institutional study highlighting the MGMT promoter methylation and IDH1 gene mutation status.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2017, Volume: 123, Issue:1

    Topics: Adult; Aged; Brain Neoplasms; Dacarbazine; DNA Methylation; DNA Modification Methylases; DNA Repair

2017
Management of malignant glioma--quo vadis?
    Onkologie, 2008, Volume: 31, Issue:6

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant; Dacarbazine; Glioma; Hum

2008
Management of malignant glioma--quo vadis?
    Onkologie, 2008, Volume: 31, Issue:6

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant; Dacarbazine; Glioma; Hum

2008
Management of malignant glioma--quo vadis?
    Onkologie, 2008, Volume: 31, Issue:6

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant; Dacarbazine; Glioma; Hum

2008
Temozolomide in newly diagnosed malignant gliomas: administered concomitantly with radiotherapy, and thereafter as consolidation treatment.
    Onkologie, 2008, Volume: 31, Issue:6

    Topics: Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant;

2008
Temozolomide in newly diagnosed malignant gliomas: administered concomitantly with radiotherapy, and thereafter as consolidation treatment.
    Onkologie, 2008, Volume: 31, Issue:6

    Topics: Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant;

2008
Temozolomide in newly diagnosed malignant gliomas: administered concomitantly with radiotherapy, and thereafter as consolidation treatment.
    Onkologie, 2008, Volume: 31, Issue:6

    Topics: Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant;

2008
Accelerated hypofractionated intensity-modulated radiotherapy with concurrent and adjuvant temozolomide for patients with glioblastoma multiforme: a safety and efficacy analysis.
    International journal of radiation oncology, biology, physics, 2009, Feb-01, Volume: 73, Issue:2

    Topics: Adult; Aged; Analysis of Variance; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy,

2009
Accelerated hypofractionated intensity-modulated radiotherapy with concurrent and adjuvant temozolomide for patients with glioblastoma multiforme: a safety and efficacy analysis.
    International journal of radiation oncology, biology, physics, 2009, Feb-01, Volume: 73, Issue:2

    Topics: Adult; Aged; Analysis of Variance; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy,

2009
Accelerated hypofractionated intensity-modulated radiotherapy with concurrent and adjuvant temozolomide for patients with glioblastoma multiforme: a safety and efficacy analysis.
    International journal of radiation oncology, biology, physics, 2009, Feb-01, Volume: 73, Issue:2

    Topics: Adult; Aged; Analysis of Variance; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy,

2009
Individual adjuvant therapy for malignant gliomas based on O6-methylguanine-DNA methyltransferase messenger RNA quantitation by real-time reverse-transcription polymerase chain-reaction.
    Oncology reports, 2008, Volume: 20, Issue:1

    Topics: Adult; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Evidence-Based Medicine; Female; Gli

2008
Individual adjuvant therapy for malignant gliomas based on O6-methylguanine-DNA methyltransferase messenger RNA quantitation by real-time reverse-transcription polymerase chain-reaction.
    Oncology reports, 2008, Volume: 20, Issue:1

    Topics: Adult; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Evidence-Based Medicine; Female; Gli

2008
Individual adjuvant therapy for malignant gliomas based on O6-methylguanine-DNA methyltransferase messenger RNA quantitation by real-time reverse-transcription polymerase chain-reaction.
    Oncology reports, 2008, Volume: 20, Issue:1

    Topics: Adult; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Evidence-Based Medicine; Female; Gli

2008
Autophagy-inducing agents augment the antitumor effect of telerase-selve oncolytic adenovirus OBP-405 on glioblastoma cells.
    Gene therapy, 2008, Volume: 15, Issue:17

    Topics: Adenoviridae; Animals; Autophagy; Brain Neoplasms; Cell Line, Tumor; Dacarbazine; Genetic Therapy; G

2008
Autophagy-inducing agents augment the antitumor effect of telerase-selve oncolytic adenovirus OBP-405 on glioblastoma cells.
    Gene therapy, 2008, Volume: 15, Issue:17

    Topics: Adenoviridae; Animals; Autophagy; Brain Neoplasms; Cell Line, Tumor; Dacarbazine; Genetic Therapy; G

2008
Autophagy-inducing agents augment the antitumor effect of telerase-selve oncolytic adenovirus OBP-405 on glioblastoma cells.
    Gene therapy, 2008, Volume: 15, Issue:17

    Topics: Adenoviridae; Animals; Autophagy; Brain Neoplasms; Cell Line, Tumor; Dacarbazine; Genetic Therapy; G

2008
Temozolomide preferentially depletes cancer stem cells in glioblastoma.
    Cancer research, 2008, Jul-15, Volume: 68, Issue:14

    Topics: AC133 Antigen; Antigens, CD; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; C

2008
Temozolomide preferentially depletes cancer stem cells in glioblastoma.
    Cancer research, 2008, Jul-15, Volume: 68, Issue:14

    Topics: AC133 Antigen; Antigens, CD; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; C

2008
Temozolomide preferentially depletes cancer stem cells in glioblastoma.
    Cancer research, 2008, Jul-15, Volume: 68, Issue:14

    Topics: AC133 Antigen; Antigens, CD; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; C

2008
Enhancement of survival of 9L gliosarcoma bearing rats following intracerebral delivery of drugs in combination with microbeam radiation therapy.
    European journal of radiology, 2008, Volume: 68, Issue:3 Suppl

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Chemotherapy, Adjuvan

2008
Enhancement of survival of 9L gliosarcoma bearing rats following intracerebral delivery of drugs in combination with microbeam radiation therapy.
    European journal of radiology, 2008, Volume: 68, Issue:3 Suppl

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Chemotherapy, Adjuvan

2008
Enhancement of survival of 9L gliosarcoma bearing rats following intracerebral delivery of drugs in combination with microbeam radiation therapy.
    European journal of radiology, 2008, Volume: 68, Issue:3 Suppl

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Chemotherapy, Adjuvan

2008
Enhanced antitumor effect of combined-modality treatment using convection-enhanced delivery of hydrophilic nitrosourea with irradiation or systemic administration of temozolomide in intracranial brain tumor xenografts.
    Neurological research, 2008, Volume: 30, Issue:9

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Cell Line, Tumor; Combined

2008
Enhanced antitumor effect of combined-modality treatment using convection-enhanced delivery of hydrophilic nitrosourea with irradiation or systemic administration of temozolomide in intracranial brain tumor xenografts.
    Neurological research, 2008, Volume: 30, Issue:9

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Cell Line, Tumor; Combined

2008
Enhanced antitumor effect of combined-modality treatment using convection-enhanced delivery of hydrophilic nitrosourea with irradiation or systemic administration of temozolomide in intracranial brain tumor xenografts.
    Neurological research, 2008, Volume: 30, Issue:9

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Cell Line, Tumor; Combined

2008
A novel tool to analyze MRI recurrence patterns in glioblastoma.
    Neuro-oncology, 2008, Volume: 10, Issue:6

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Glioblas

2008
A novel tool to analyze MRI recurrence patterns in glioblastoma.
    Neuro-oncology, 2008, Volume: 10, Issue:6

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Glioblas

2008
A novel tool to analyze MRI recurrence patterns in glioblastoma.
    Neuro-oncology, 2008, Volume: 10, Issue:6

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Glioblas

2008
Mismatch repair deficiency does not mediate clinical resistance to temozolomide in malignant glioma.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2008, Aug-01, Volume: 14, Issue:15

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Base Pair Mismatch; Brain Neoplas

2008
Mismatch repair deficiency does not mediate clinical resistance to temozolomide in malignant glioma.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2008, Aug-01, Volume: 14, Issue:15

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Base Pair Mismatch; Brain Neoplas

2008
Mismatch repair deficiency does not mediate clinical resistance to temozolomide in malignant glioma.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2008, Aug-01, Volume: 14, Issue:15

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Base Pair Mismatch; Brain Neoplas

2008
Efficacy of the HSP90 inhibitor 17-AAG in human glioma cell lines and tumorigenic glioma stem cells.
    Neuro-oncology, 2009, Volume: 11, Issue:2

    Topics: Animals; Antineoplastic Agents, Alkylating; Benzoquinones; Blotting, Western; Brain Neoplasms; Cell

2009
Efficacy of the HSP90 inhibitor 17-AAG in human glioma cell lines and tumorigenic glioma stem cells.
    Neuro-oncology, 2009, Volume: 11, Issue:2

    Topics: Animals; Antineoplastic Agents, Alkylating; Benzoquinones; Blotting, Western; Brain Neoplasms; Cell

2009
Efficacy of the HSP90 inhibitor 17-AAG in human glioma cell lines and tumorigenic glioma stem cells.
    Neuro-oncology, 2009, Volume: 11, Issue:2

    Topics: Animals; Antineoplastic Agents, Alkylating; Benzoquinones; Blotting, Western; Brain Neoplasms; Cell

2009
A MDR1 (ABCB1) gene single nucleotide polymorphism predicts outcome of temozolomide treatment in glioblastoma patients.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2009, Volume: 20, Issue:1

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; ATP Binding Cassette

2009
A MDR1 (ABCB1) gene single nucleotide polymorphism predicts outcome of temozolomide treatment in glioblastoma patients.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2009, Volume: 20, Issue:1

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; ATP Binding Cassette

2009
A MDR1 (ABCB1) gene single nucleotide polymorphism predicts outcome of temozolomide treatment in glioblastoma patients.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2009, Volume: 20, Issue:1

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; ATP Binding Cassette

2009
Quality of life in low-grade glioma patients receiving temozolomide.
    Neuro-oncology, 2009, Volume: 11, Issue:1

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neoplasms; Dacarbazine; Female; H

2009
Quality of life in low-grade glioma patients receiving temozolomide.
    Neuro-oncology, 2009, Volume: 11, Issue:1

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neoplasms; Dacarbazine; Female; H

2009
Quality of life in low-grade glioma patients receiving temozolomide.
    Neuro-oncology, 2009, Volume: 11, Issue:1

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neoplasms; Dacarbazine; Female; H

2009
Disseminated salmonellosis in a patient treated with temozolomide.
    The Journal of infection, 2008, Volume: 57, Issue:5

    Topics: Adult; Anti-Infective Agents; Antineoplastic Agents, Alkylating; Arthritis, Infectious; Astrocytoma;

2008
Disseminated salmonellosis in a patient treated with temozolomide.
    The Journal of infection, 2008, Volume: 57, Issue:5

    Topics: Adult; Anti-Infective Agents; Antineoplastic Agents, Alkylating; Arthritis, Infectious; Astrocytoma;

2008
Disseminated salmonellosis in a patient treated with temozolomide.
    The Journal of infection, 2008, Volume: 57, Issue:5

    Topics: Adult; Anti-Infective Agents; Antineoplastic Agents, Alkylating; Arthritis, Infectious; Astrocytoma;

2008
Therapeutic efficacy of a herpes simplex virus with radiation or temozolomide for intracranial glioblastoma after convection-enhanced delivery.
    Molecular therapy : the journal of the American Society of Gene Therapy, 2008, Volume: 16, Issue:11

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Convection;

2008
Therapeutic efficacy of a herpes simplex virus with radiation or temozolomide for intracranial glioblastoma after convection-enhanced delivery.
    Molecular therapy : the journal of the American Society of Gene Therapy, 2008, Volume: 16, Issue:11

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Convection;

2008
Therapeutic efficacy of a herpes simplex virus with radiation or temozolomide for intracranial glioblastoma after convection-enhanced delivery.
    Molecular therapy : the journal of the American Society of Gene Therapy, 2008, Volume: 16, Issue:11

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Convection;

2008
Temozolomide rechallenge in recurrent malignant glioma by using a continuous temozolomide schedule: the "rescue" approach.
    Cancer, 2008, Oct-15, Volume: 113, Issue:8

    Topics: Adult; Aged; Antineoplastic Agents; Brain Neoplasms; Dacarbazine; Disease-Free Survival; Female; Gli

2008
Temozolomide rechallenge in recurrent malignant glioma by using a continuous temozolomide schedule: the "rescue" approach.
    Cancer, 2008, Oct-15, Volume: 113, Issue:8

    Topics: Adult; Aged; Antineoplastic Agents; Brain Neoplasms; Dacarbazine; Disease-Free Survival; Female; Gli

2008
Temozolomide rechallenge in recurrent malignant glioma by using a continuous temozolomide schedule: the "rescue" approach.
    Cancer, 2008, Oct-15, Volume: 113, Issue:8

    Topics: Adult; Aged; Antineoplastic Agents; Brain Neoplasms; Dacarbazine; Disease-Free Survival; Female; Gli

2008
Effects, in an in-vivo model system, of 1,2,3,4-tetrahydroisoquinoline on glioma.
    Anti-cancer drugs, 2008, Volume: 19, Issue:9

    Topics: Animals; Antineoplastic Agents; Astrocytes; Brain Neoplasms; Carmustine; Cell Line, Tumor; Dacarbazi

2008
Effects, in an in-vivo model system, of 1,2,3,4-tetrahydroisoquinoline on glioma.
    Anti-cancer drugs, 2008, Volume: 19, Issue:9

    Topics: Animals; Antineoplastic Agents; Astrocytes; Brain Neoplasms; Carmustine; Cell Line, Tumor; Dacarbazi

2008
Effects, in an in-vivo model system, of 1,2,3,4-tetrahydroisoquinoline on glioma.
    Anti-cancer drugs, 2008, Volume: 19, Issue:9

    Topics: Animals; Antineoplastic Agents; Astrocytes; Brain Neoplasms; Carmustine; Cell Line, Tumor; Dacarbazi

2008
Cytotoxic and apoptotic effects of bortezomib and gefitinib compared to alkylating agents on human glioblastoma cells.
    Journal of experimental therapeutics & oncology, 2008, Volume: 7, Issue:2

    Topics: Animals; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Apoptosis; Boronic Acids; Bortezo

2008
Cytotoxic and apoptotic effects of bortezomib and gefitinib compared to alkylating agents on human glioblastoma cells.
    Journal of experimental therapeutics & oncology, 2008, Volume: 7, Issue:2

    Topics: Animals; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Apoptosis; Boronic Acids; Bortezo

2008
Cytotoxic and apoptotic effects of bortezomib and gefitinib compared to alkylating agents on human glioblastoma cells.
    Journal of experimental therapeutics & oncology, 2008, Volume: 7, Issue:2

    Topics: Animals; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Apoptosis; Boronic Acids; Bortezo

2008
DNA repair enzyme expression and differential response to temozolomide in a patient with both glioblastoma and metastatic pancreatic neuroendocrine tumor.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2008, Oct-10, Volume: 26, Issue:29

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2008
DNA repair enzyme expression and differential response to temozolomide in a patient with both glioblastoma and metastatic pancreatic neuroendocrine tumor.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2008, Oct-10, Volume: 26, Issue:29

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2008
DNA repair enzyme expression and differential response to temozolomide in a patient with both glioblastoma and metastatic pancreatic neuroendocrine tumor.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2008, Oct-10, Volume: 26, Issue:29

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2008
Sagopilone crosses the blood-brain barrier in vivo to inhibit brain tumor growth and metastases.
    Neuro-oncology, 2009, Volume: 11, Issue:2

    Topics: Animals; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Phytogenic; Benzothiazoles; Blood

2009
Sagopilone crosses the blood-brain barrier in vivo to inhibit brain tumor growth and metastases.
    Neuro-oncology, 2009, Volume: 11, Issue:2

    Topics: Animals; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Phytogenic; Benzothiazoles; Blood

2009
Sagopilone crosses the blood-brain barrier in vivo to inhibit brain tumor growth and metastases.
    Neuro-oncology, 2009, Volume: 11, Issue:2

    Topics: Animals; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Phytogenic; Benzothiazoles; Blood

2009
Frequently asked questions in the medical management of high-grade glioma: a short guide with practical answers.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2008, Volume: 19 Suppl 7

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant; Clinical Trials as Topic

2008
Frequently asked questions in the medical management of high-grade glioma: a short guide with practical answers.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2008, Volume: 19 Suppl 7

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant; Clinical Trials as Topic

2008
Frequently asked questions in the medical management of high-grade glioma: a short guide with practical answers.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2008, Volume: 19 Suppl 7

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant; Clinical Trials as Topic

2008
Low-grade glioma: a challenge in therapeutic options: the role of radiotherapy.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2008, Volume: 19 Suppl 7

    Topics: Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Chemotherapy, Adjuvant; Dacarbazine

2008
Low-grade glioma: a challenge in therapeutic options: the role of radiotherapy.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2008, Volume: 19 Suppl 7

    Topics: Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Chemotherapy, Adjuvant; Dacarbazine

2008
Low-grade glioma: a challenge in therapeutic options: the role of radiotherapy.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2008, Volume: 19 Suppl 7

    Topics: Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Chemotherapy, Adjuvant; Dacarbazine

2008
Feasibility of using bevacizumab with radiation therapy and temozolomide in newly diagnosed high-grade glioma.
    International journal of radiation oncology, biology, physics, 2008, Oct-01, Volume: 72, Issue:2

    Topics: Adult; Aged; Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Ant

2008
Feasibility of using bevacizumab with radiation therapy and temozolomide in newly diagnosed high-grade glioma.
    International journal of radiation oncology, biology, physics, 2008, Oct-01, Volume: 72, Issue:2

    Topics: Adult; Aged; Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Ant

2008
Feasibility of using bevacizumab with radiation therapy and temozolomide in newly diagnosed high-grade glioma.
    International journal of radiation oncology, biology, physics, 2008, Oct-01, Volume: 72, Issue:2

    Topics: Adult; Aged; Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Ant

2008
The prognostic value of nestin expression in newly diagnosed glioblastoma: report from the Radiation Therapy Oncology Group.
    Radiation oncology (London, England), 2008, Sep-25, Volume: 3

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Lineage; Combined Modality Therapy; Dacarba

2008
The prognostic value of nestin expression in newly diagnosed glioblastoma: report from the Radiation Therapy Oncology Group.
    Radiation oncology (London, England), 2008, Sep-25, Volume: 3

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Lineage; Combined Modality Therapy; Dacarba

2008
The prognostic value of nestin expression in newly diagnosed glioblastoma: report from the Radiation Therapy Oncology Group.
    Radiation oncology (London, England), 2008, Sep-25, Volume: 3

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Lineage; Combined Modality Therapy; Dacarba

2008
Concomitant (without adjuvant) temozolomide and radiation to treat glioblastoma: a retrospective study.
    Clinical oncology (Royal College of Radiologists (Great Britain)), 2009, Volume: 21, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Ad

2009
Concomitant (without adjuvant) temozolomide and radiation to treat glioblastoma: a retrospective study.
    Clinical oncology (Royal College of Radiologists (Great Britain)), 2009, Volume: 21, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Ad

2009
Concomitant (without adjuvant) temozolomide and radiation to treat glioblastoma: a retrospective study.
    Clinical oncology (Royal College of Radiologists (Great Britain)), 2009, Volume: 21, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Ad

2009
Independent association of extent of resection with survival in patients with malignant brain astrocytoma.
    Journal of neurosurgery, 2009, Volume: 110, Issue:1

    Topics: Aged; Analysis of Variance; Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neoplasms; Carmust

2009
Independent association of extent of resection with survival in patients with malignant brain astrocytoma.
    Journal of neurosurgery, 2009, Volume: 110, Issue:1

    Topics: Aged; Analysis of Variance; Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neoplasms; Carmust

2009
Independent association of extent of resection with survival in patients with malignant brain astrocytoma.
    Journal of neurosurgery, 2009, Volume: 110, Issue:1

    Topics: Aged; Analysis of Variance; Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neoplasms; Carmust

2009
MGMT promoter hypermethylation correlates with a survival benefit from temozolomide in patients with recurrent anaplastic astrocytoma but not glioblastoma.
    European journal of cancer (Oxford, England : 1990), 2009, Volume: 45, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neoplasms; Dac

2009
MGMT promoter hypermethylation correlates with a survival benefit from temozolomide in patients with recurrent anaplastic astrocytoma but not glioblastoma.
    European journal of cancer (Oxford, England : 1990), 2009, Volume: 45, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neoplasms; Dac

2009
MGMT promoter hypermethylation correlates with a survival benefit from temozolomide in patients with recurrent anaplastic astrocytoma but not glioblastoma.
    European journal of cancer (Oxford, England : 1990), 2009, Volume: 45, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neoplasms; Dac

2009
[Alveolo-interstitial pneumonia due to Temozolamide].
    Revue des maladies respiratoires, 2008, Volume: 25, Issue:7

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Bronchoalveolar Lavage; Dacarbazine; Female; Gli

2008
[Alveolo-interstitial pneumonia due to Temozolamide].
    Revue des maladies respiratoires, 2008, Volume: 25, Issue:7

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Bronchoalveolar Lavage; Dacarbazine; Female; Gli

2008
[Alveolo-interstitial pneumonia due to Temozolamide].
    Revue des maladies respiratoires, 2008, Volume: 25, Issue:7

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Bronchoalveolar Lavage; Dacarbazine; Female; Gli

2008
Proapoptotic receptor agonists, targeted radionuclide therapy, and the treatment of central nervous system malignancies: in regard to Fiveash et Al. (Int J Radiat Oncol Biol Phys 2008;71:507-516).
    International journal of radiation oncology, biology, physics, 2008, Nov-15, Volume: 72, Issue:4

    Topics: Animals; Antibodies, Monoclonal; Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cell

2008
Proapoptotic receptor agonists, targeted radionuclide therapy, and the treatment of central nervous system malignancies: in regard to Fiveash et Al. (Int J Radiat Oncol Biol Phys 2008;71:507-516).
    International journal of radiation oncology, biology, physics, 2008, Nov-15, Volume: 72, Issue:4

    Topics: Animals; Antibodies, Monoclonal; Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cell

2008
Proapoptotic receptor agonists, targeted radionuclide therapy, and the treatment of central nervous system malignancies: in regard to Fiveash et Al. (Int J Radiat Oncol Biol Phys 2008;71:507-516).
    International journal of radiation oncology, biology, physics, 2008, Nov-15, Volume: 72, Issue:4

    Topics: Animals; Antibodies, Monoclonal; Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cell

2008
Differential effect of sunitinib on the distribution of temozolomide in an orthotopic glioma model.
    Neuro-oncology, 2009, Volume: 11, Issue:3

    Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Agents; Brain Neoplasms; Dacarbazine; Drug Interact

2009
Differential effect of sunitinib on the distribution of temozolomide in an orthotopic glioma model.
    Neuro-oncology, 2009, Volume: 11, Issue:3

    Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Agents; Brain Neoplasms; Dacarbazine; Drug Interact

2009
Differential effect of sunitinib on the distribution of temozolomide in an orthotopic glioma model.
    Neuro-oncology, 2009, Volume: 11, Issue:3

    Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Agents; Brain Neoplasms; Dacarbazine; Drug Interact

2009
Tuberculosis in a patient on temozolomide: a case report.
    Journal of neuro-oncology, 2009, Volume: 92, Issue:1

    Topics: Anti-Infective Agents; Anti-Inflammatory Agents; Anti-Ulcer Agents; Antibiotics, Antitubercular; Ant

2009
Tuberculosis in a patient on temozolomide: a case report.
    Journal of neuro-oncology, 2009, Volume: 92, Issue:1

    Topics: Anti-Infective Agents; Anti-Inflammatory Agents; Anti-Ulcer Agents; Antibiotics, Antitubercular; Ant

2009
Tuberculosis in a patient on temozolomide: a case report.
    Journal of neuro-oncology, 2009, Volume: 92, Issue:1

    Topics: Anti-Infective Agents; Anti-Inflammatory Agents; Anti-Ulcer Agents; Antibiotics, Antitubercular; Ant

2009
Characterization of a side population of astrocytoma cells in response to temozolomide.
    Journal of neurosurgery, 2008, Volume: 109, Issue:5

    Topics: Animals; Antineoplastic Agents, Alkylating; Astrocytoma; ATP Binding Cassette Transporter, Subfamily

2008
Characterization of a side population of astrocytoma cells in response to temozolomide.
    Journal of neurosurgery, 2008, Volume: 109, Issue:5

    Topics: Animals; Antineoplastic Agents, Alkylating; Astrocytoma; ATP Binding Cassette Transporter, Subfamily

2008
Characterization of a side population of astrocytoma cells in response to temozolomide.
    Journal of neurosurgery, 2008, Volume: 109, Issue:5

    Topics: Animals; Antineoplastic Agents, Alkylating; Astrocytoma; ATP Binding Cassette Transporter, Subfamily

2008
ACNU-based chemotherapy for recurrent glioma in the temozolomide era.
    Journal of neuro-oncology, 2009, Volume: 92, Issue:1

    Topics: Adult; Aged; Antineoplastic Agents; Brain Neoplasms; Dacarbazine; Disease-Free Survival; Female; Gli

2009
ACNU-based chemotherapy for recurrent glioma in the temozolomide era.
    Journal of neuro-oncology, 2009, Volume: 92, Issue:1

    Topics: Adult; Aged; Antineoplastic Agents; Brain Neoplasms; Dacarbazine; Disease-Free Survival; Female; Gli

2009
ACNU-based chemotherapy for recurrent glioma in the temozolomide era.
    Journal of neuro-oncology, 2009, Volume: 92, Issue:1

    Topics: Adult; Aged; Antineoplastic Agents; Brain Neoplasms; Dacarbazine; Disease-Free Survival; Female; Gli

2009
Treatment-related myelodysplastic syndrome after temozolomide use in a child: first report.
    Journal of pediatric hematology/oncology, 2008, Volume: 30, Issue:11

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Child; Combined Modality Therapy; Cranial Irradi

2008
Treatment-related myelodysplastic syndrome after temozolomide use in a child: first report.
    Journal of pediatric hematology/oncology, 2008, Volume: 30, Issue:11

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Child; Combined Modality Therapy; Cranial Irradi

2008
Treatment-related myelodysplastic syndrome after temozolomide use in a child: first report.
    Journal of pediatric hematology/oncology, 2008, Volume: 30, Issue:11

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Child; Combined Modality Therapy; Cranial Irradi

2008
Optimizing radiotherapy of brain tumours by a combination of temozolomide & lonidamine.
    The Indian journal of medical research, 2008, Volume: 128, Issue:2

    Topics: Acridine Orange; Analysis of Variance; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line

2008
Optimizing radiotherapy of brain tumours by a combination of temozolomide & lonidamine.
    The Indian journal of medical research, 2008, Volume: 128, Issue:2

    Topics: Acridine Orange; Analysis of Variance; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line

2008
Optimizing radiotherapy of brain tumours by a combination of temozolomide & lonidamine.
    The Indian journal of medical research, 2008, Volume: 128, Issue:2

    Topics: Acridine Orange; Analysis of Variance; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line

2008
Evaluation of MGMT promoter methylation status and correlation with temozolomide response in orthotopic glioblastoma xenograft model.
    Journal of neuro-oncology, 2009, Volume: 92, Issue:1

    Topics: Animals; Antineoplastic Agents, Alkylating; Base Sequence; Blotting, Western; Brain Neoplasms; Dacar

2009
Evaluation of MGMT promoter methylation status and correlation with temozolomide response in orthotopic glioblastoma xenograft model.
    Journal of neuro-oncology, 2009, Volume: 92, Issue:1

    Topics: Animals; Antineoplastic Agents, Alkylating; Base Sequence; Blotting, Western; Brain Neoplasms; Dacar

2009
Evaluation of MGMT promoter methylation status and correlation with temozolomide response in orthotopic glioblastoma xenograft model.
    Journal of neuro-oncology, 2009, Volume: 92, Issue:1

    Topics: Animals; Antineoplastic Agents, Alkylating; Base Sequence; Blotting, Western; Brain Neoplasms; Dacar

2009
Erythropoietin augments survival of glioma cells after radiation and temozolomide.
    International journal of radiation oncology, biology, physics, 2008, Nov-01, Volume: 72, Issue:3

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Division; Cell Line, Tumor; Cell M

2008
Erythropoietin augments survival of glioma cells after radiation and temozolomide.
    International journal of radiation oncology, biology, physics, 2008, Nov-01, Volume: 72, Issue:3

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Division; Cell Line, Tumor; Cell M

2008
Erythropoietin augments survival of glioma cells after radiation and temozolomide.
    International journal of radiation oncology, biology, physics, 2008, Nov-01, Volume: 72, Issue:3

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Division; Cell Line, Tumor; Cell M

2008
Activation of KATP channels increases anticancer drug delivery to brain tumors and survival.
    European journal of pharmacology, 2009, Jan-14, Volume: 602, Issue:2-3

    Topics: Animals; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Antineopl

2009
Activation of KATP channels increases anticancer drug delivery to brain tumors and survival.
    European journal of pharmacology, 2009, Jan-14, Volume: 602, Issue:2-3

    Topics: Animals; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Antineopl

2009
Activation of KATP channels increases anticancer drug delivery to brain tumors and survival.
    European journal of pharmacology, 2009, Jan-14, Volume: 602, Issue:2-3

    Topics: Animals; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Antineopl

2009
Radiochemotherapy in patients with primary glioblastoma comparing two temozolomide dose regimens: is the survival really so impressive?: in regard to Combs et al. (Int J Radiat Oncol Biol Phys 2008;71:999-1005).
    International journal of radiation oncology, biology, physics, 2008, Dec-01, Volume: 72, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Follow-U

2008
Radiochemotherapy in patients with primary glioblastoma comparing two temozolomide dose regimens: is the survival really so impressive?: in regard to Combs et al. (Int J Radiat Oncol Biol Phys 2008;71:999-1005).
    International journal of radiation oncology, biology, physics, 2008, Dec-01, Volume: 72, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Follow-U

2008
Radiochemotherapy in patients with primary glioblastoma comparing two temozolomide dose regimens: is the survival really so impressive?: in regard to Combs et al. (Int J Radiat Oncol Biol Phys 2008;71:999-1005).
    International journal of radiation oncology, biology, physics, 2008, Dec-01, Volume: 72, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Follow-U

2008
Prolonged and severe thrombocytopenia with pancytopenia induced by radiation-combined temozolomide therapy in a patient with newly diagnosed glioblastoma--analysis of O6-methylguanine-DNA methyltransferase status.
    Journal of neuro-oncology, 2009, Volume: 92, Issue:2

    Topics: Antineoplastic Agents, Alkylating; Base Sequence; Blotting, Western; Brain Neoplasms; Combined Modal

2009
Prolonged and severe thrombocytopenia with pancytopenia induced by radiation-combined temozolomide therapy in a patient with newly diagnosed glioblastoma--analysis of O6-methylguanine-DNA methyltransferase status.
    Journal of neuro-oncology, 2009, Volume: 92, Issue:2

    Topics: Antineoplastic Agents, Alkylating; Base Sequence; Blotting, Western; Brain Neoplasms; Combined Modal

2009
Prolonged and severe thrombocytopenia with pancytopenia induced by radiation-combined temozolomide therapy in a patient with newly diagnosed glioblastoma--analysis of O6-methylguanine-DNA methyltransferase status.
    Journal of neuro-oncology, 2009, Volume: 92, Issue:2

    Topics: Antineoplastic Agents, Alkylating; Base Sequence; Blotting, Western; Brain Neoplasms; Combined Modal

2009
Targeted inhibition of cyclic AMP phosphodiesterase-4 promotes brain tumor regression.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2008, Dec-01, Volume: 14, Issue:23

    Topics: Adolescent; Adult; Aged; Animals; Antineoplastic Agents; Blotting, Western; Brain Neoplasms; Cell Li

2008
Targeted inhibition of cyclic AMP phosphodiesterase-4 promotes brain tumor regression.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2008, Dec-01, Volume: 14, Issue:23

    Topics: Adolescent; Adult; Aged; Animals; Antineoplastic Agents; Blotting, Western; Brain Neoplasms; Cell Li

2008
Targeted inhibition of cyclic AMP phosphodiesterase-4 promotes brain tumor regression.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2008, Dec-01, Volume: 14, Issue:23

    Topics: Adolescent; Adult; Aged; Animals; Antineoplastic Agents; Blotting, Western; Brain Neoplasms; Cell Li

2008
Combining bevacizumab with temozolomide increases the antitumor efficacy of temozolomide in a human glioblastoma orthotopic xenograft model.
    Neoplasia (New York, N.Y.), 2008, Volume: 10, Issue:12

    Topics: Angiogenesis Inhibitors; Animals; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineo

2008
Combining bevacizumab with temozolomide increases the antitumor efficacy of temozolomide in a human glioblastoma orthotopic xenograft model.
    Neoplasia (New York, N.Y.), 2008, Volume: 10, Issue:12

    Topics: Angiogenesis Inhibitors; Animals; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineo

2008
Combining bevacizumab with temozolomide increases the antitumor efficacy of temozolomide in a human glioblastoma orthotopic xenograft model.
    Neoplasia (New York, N.Y.), 2008, Volume: 10, Issue:12

    Topics: Angiogenesis Inhibitors; Animals; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineo

2008
Radiotherapy followed by adjuvant temozolomide treatment of malignant glioma.
    Surgical neurology, 2008, Volume: 70 Suppl 1

    Topics: Antineoplastic Agents, Alkylating; Biopsy; Brain Neoplasms; Dacarbazine; Female; Follow-Up Studies;

2008
Radiotherapy followed by adjuvant temozolomide treatment of malignant glioma.
    Surgical neurology, 2008, Volume: 70 Suppl 1

    Topics: Antineoplastic Agents, Alkylating; Biopsy; Brain Neoplasms; Dacarbazine; Female; Follow-Up Studies;

2008
Radiotherapy followed by adjuvant temozolomide treatment of malignant glioma.
    Surgical neurology, 2008, Volume: 70 Suppl 1

    Topics: Antineoplastic Agents, Alkylating; Biopsy; Brain Neoplasms; Dacarbazine; Female; Follow-Up Studies;

2008
Pituitary carcinoma presenting with multiple metastases: case report.
    Journal of child neurology, 2008, Volume: 23, Issue:12

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Child; Dacarbazine; Female; Humans; Magnetic Res

2008
Pituitary carcinoma presenting with multiple metastases: case report.
    Journal of child neurology, 2008, Volume: 23, Issue:12

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Child; Dacarbazine; Female; Humans; Magnetic Res

2008
Pituitary carcinoma presenting with multiple metastases: case report.
    Journal of child neurology, 2008, Volume: 23, Issue:12

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Child; Dacarbazine; Female; Humans; Magnetic Res

2008
p53 Small-molecule inhibitor enhances temozolomide cytotoxic activity against intracranial glioblastoma xenografts.
    Cancer research, 2008, Dec-15, Volume: 68, Issue:24

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Benzothiazoles; Brain Neoplasms; Dacarbazin

2008
p53 Small-molecule inhibitor enhances temozolomide cytotoxic activity against intracranial glioblastoma xenografts.
    Cancer research, 2008, Dec-15, Volume: 68, Issue:24

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Benzothiazoles; Brain Neoplasms; Dacarbazin

2008
p53 Small-molecule inhibitor enhances temozolomide cytotoxic activity against intracranial glioblastoma xenografts.
    Cancer research, 2008, Dec-15, Volume: 68, Issue:24

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Benzothiazoles; Brain Neoplasms; Dacarbazin

2008
[Diagnostic and treatment delays do not modify the treatment outcome of patients with multiform glioblastoma].
    Cancer radiotherapie : journal de la Societe francaise de radiotherapie oncologique, 2009, Volume: 13, Issue:1

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Brain Neoplasms; Carmustine; Chil

2009
[Diagnostic and treatment delays do not modify the treatment outcome of patients with multiform glioblastoma].
    Cancer radiotherapie : journal de la Societe francaise de radiotherapie oncologique, 2009, Volume: 13, Issue:1

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Brain Neoplasms; Carmustine; Chil

2009
[Diagnostic and treatment delays do not modify the treatment outcome of patients with multiform glioblastoma].
    Cancer radiotherapie : journal de la Societe francaise de radiotherapie oncologique, 2009, Volume: 13, Issue:1

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Brain Neoplasms; Carmustine; Chil

2009
Extended exposure to alkylator chemotherapy: delayed appearance of myelodysplasia.
    Journal of neuro-oncology, 2009, Volume: 93, Issue:2

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Female; Follow-Up Stud

2009
Extended exposure to alkylator chemotherapy: delayed appearance of myelodysplasia.
    Journal of neuro-oncology, 2009, Volume: 93, Issue:2

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Female; Follow-Up Stud

2009
Extended exposure to alkylator chemotherapy: delayed appearance of myelodysplasia.
    Journal of neuro-oncology, 2009, Volume: 93, Issue:2

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Female; Follow-Up Stud

2009
Efficacy of temozolomide for recurrent embryonal brain tumors in children.
    Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 2009, Volume: 25, Issue:5

    Topics: Administration, Oral; Adolescent; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; D

2009
Efficacy of temozolomide for recurrent embryonal brain tumors in children.
    Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 2009, Volume: 25, Issue:5

    Topics: Administration, Oral; Adolescent; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; D

2009
Efficacy of temozolomide for recurrent embryonal brain tumors in children.
    Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 2009, Volume: 25, Issue:5

    Topics: Administration, Oral; Adolescent; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; D

2009
Early clinical and neuroradiological worsening after radiotherapy and concomitant temozolomide in patients with glioblastoma: tumour progression or radionecrosis?
    Clinical neurology and neurosurgery, 2009, Volume: 111, Issue:4

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Ataxia; Brain Neoplasms; Chemotherapy, Adjuvant; Con

2009
Early clinical and neuroradiological worsening after radiotherapy and concomitant temozolomide in patients with glioblastoma: tumour progression or radionecrosis?
    Clinical neurology and neurosurgery, 2009, Volume: 111, Issue:4

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Ataxia; Brain Neoplasms; Chemotherapy, Adjuvant; Con

2009
Early clinical and neuroradiological worsening after radiotherapy and concomitant temozolomide in patients with glioblastoma: tumour progression or radionecrosis?
    Clinical neurology and neurosurgery, 2009, Volume: 111, Issue:4

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Ataxia; Brain Neoplasms; Chemotherapy, Adjuvant; Con

2009
A new model for prediction of drug distribution in tumor and normal tissues: pharmacokinetics of temozolomide in glioma patients.
    Cancer research, 2009, Jan-01, Volume: 69, Issue:1

    Topics: Administration, Oral; Antineoplastic Agents, Alkylating; Brain; Brain Neoplasms; Carbon Radioisotope

2009
A new model for prediction of drug distribution in tumor and normal tissues: pharmacokinetics of temozolomide in glioma patients.
    Cancer research, 2009, Jan-01, Volume: 69, Issue:1

    Topics: Administration, Oral; Antineoplastic Agents, Alkylating; Brain; Brain Neoplasms; Carbon Radioisotope

2009
A new model for prediction of drug distribution in tumor and normal tissues: pharmacokinetics of temozolomide in glioma patients.
    Cancer research, 2009, Jan-01, Volume: 69, Issue:1

    Topics: Administration, Oral; Antineoplastic Agents, Alkylating; Brain; Brain Neoplasms; Carbon Radioisotope

2009
Anti-proliferative effect of the gastrin-release peptide receptor antagonist RC-3095 plus temozolomide in experimental glioblastoma models.
    Journal of neuro-oncology, 2009, Volume: 93, Issue:2

    Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bombesin; Brain Neop

2009
Anti-proliferative effect of the gastrin-release peptide receptor antagonist RC-3095 plus temozolomide in experimental glioblastoma models.
    Journal of neuro-oncology, 2009, Volume: 93, Issue:2

    Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bombesin; Brain Neop

2009
Anti-proliferative effect of the gastrin-release peptide receptor antagonist RC-3095 plus temozolomide in experimental glioblastoma models.
    Journal of neuro-oncology, 2009, Volume: 93, Issue:2

    Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bombesin; Brain Neop

2009
High-dose radiotherapy to 78 Gy with or without temozolomide for high grade gliomas.
    Journal of neuro-oncology, 2009, Volume: 93, Issue:3

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Comb

2009
High-dose radiotherapy to 78 Gy with or without temozolomide for high grade gliomas.
    Journal of neuro-oncology, 2009, Volume: 93, Issue:3

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Comb

2009
High-dose radiotherapy to 78 Gy with or without temozolomide for high grade gliomas.
    Journal of neuro-oncology, 2009, Volume: 93, Issue:3

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Comb

2009
In vitro and in vivo radiosensitization of glioblastoma cells by the poly (ADP-ribose) polymerase inhibitor E7016.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2009, Jan-15, Volume: 15, Issue:2

    Topics: Animals; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Comet Assay; Dacarbazine; DNA Repair; Enzyme

2009
In vitro and in vivo radiosensitization of glioblastoma cells by the poly (ADP-ribose) polymerase inhibitor E7016.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2009, Jan-15, Volume: 15, Issue:2

    Topics: Animals; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Comet Assay; Dacarbazine; DNA Repair; Enzyme

2009
In vitro and in vivo radiosensitization of glioblastoma cells by the poly (ADP-ribose) polymerase inhibitor E7016.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2009, Jan-15, Volume: 15, Issue:2

    Topics: Animals; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Comet Assay; Dacarbazine; DNA Repair; Enzyme

2009
Pseudoprogression after radiotherapy with concurrent temozolomide for high-grade glioma: clinical observations and working recommendations.
    Surgical neurology, 2009, Volume: 72, Issue:4

    Topics: Adult; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; D

2009
Pseudoprogression after radiotherapy with concurrent temozolomide for high-grade glioma: clinical observations and working recommendations.
    Surgical neurology, 2009, Volume: 72, Issue:4

    Topics: Adult; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; D

2009
Pseudoprogression after radiotherapy with concurrent temozolomide for high-grade glioma: clinical observations and working recommendations.
    Surgical neurology, 2009, Volume: 72, Issue:4

    Topics: Adult; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; D

2009
Combined magnetic resonance and fluorescence imaging of the living mouse brain reveals glioma response to chemotherapy.
    NeuroImage, 2009, Apr-01, Volume: 45, Issue:2

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Dacarbazine; Glioma;

2009
Combined magnetic resonance and fluorescence imaging of the living mouse brain reveals glioma response to chemotherapy.
    NeuroImage, 2009, Apr-01, Volume: 45, Issue:2

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Dacarbazine; Glioma;

2009
Combined magnetic resonance and fluorescence imaging of the living mouse brain reveals glioma response to chemotherapy.
    NeuroImage, 2009, Apr-01, Volume: 45, Issue:2

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Dacarbazine; Glioma;

2009
Risk analysis of severe myelotoxicity with temozolomide: the effects of clinical and genetic factors.
    Neuro-oncology, 2009, Volume: 11, Issue:6

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Biomarkers, Tumor; Br

2009
Risk analysis of severe myelotoxicity with temozolomide: the effects of clinical and genetic factors.
    Neuro-oncology, 2009, Volume: 11, Issue:6

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Biomarkers, Tumor; Br

2009
Risk analysis of severe myelotoxicity with temozolomide: the effects of clinical and genetic factors.
    Neuro-oncology, 2009, Volume: 11, Issue:6

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Biomarkers, Tumor; Br

2009
Recurrence pattern after temozolomide concomitant with and adjuvant to radiotherapy in newly diagnosed patients with glioblastoma: correlation With MGMT promoter methylation status.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2009, Mar-10, Volume: 27, Issue:8

    Topics: Adult; Aged; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; DNA Methylation; DNA Modificat

2009
Recurrence pattern after temozolomide concomitant with and adjuvant to radiotherapy in newly diagnosed patients with glioblastoma: correlation With MGMT promoter methylation status.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2009, Mar-10, Volume: 27, Issue:8

    Topics: Adult; Aged; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; DNA Methylation; DNA Modificat

2009
Recurrence pattern after temozolomide concomitant with and adjuvant to radiotherapy in newly diagnosed patients with glioblastoma: correlation With MGMT promoter methylation status.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2009, Mar-10, Volume: 27, Issue:8

    Topics: Adult; Aged; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; DNA Methylation; DNA Modificat

2009
Editorial: on the road to multi-modal and pluri-disciplinary treatment of glioblastomas.
    Acta neurochirurgica, 2009, Volume: 151, Issue:2

    Topics: Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Brain

2009
Editorial: on the road to multi-modal and pluri-disciplinary treatment of glioblastomas.
    Acta neurochirurgica, 2009, Volume: 151, Issue:2

    Topics: Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Brain

2009
Editorial: on the road to multi-modal and pluri-disciplinary treatment of glioblastomas.
    Acta neurochirurgica, 2009, Volume: 151, Issue:2

    Topics: Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Brain

2009
Tonsillary carcinoma after temozolomide treatment for glioblastoma multiforme: treatment-related or dual-pathology?
    Journal of neuro-oncology, 2009, Volume: 94, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Carcinoma, Squamous Cell; Dacarbazine; Glioblast

2009
Tonsillary carcinoma after temozolomide treatment for glioblastoma multiforme: treatment-related or dual-pathology?
    Journal of neuro-oncology, 2009, Volume: 94, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Carcinoma, Squamous Cell; Dacarbazine; Glioblast

2009
Tonsillary carcinoma after temozolomide treatment for glioblastoma multiforme: treatment-related or dual-pathology?
    Journal of neuro-oncology, 2009, Volume: 94, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Carcinoma, Squamous Cell; Dacarbazine; Glioblast

2009
Cilengitide modulates attachment and viability of human glioma cells, but not sensitivity to irradiation or temozolomide in vitro.
    Neuro-oncology, 2009, Volume: 11, Issue:6

    Topics: Animals; Antineoplastic Agents, Alkylating; bcl-X Protein; Brain Neoplasms; Cell Adhesion; Cell Move

2009
Cilengitide modulates attachment and viability of human glioma cells, but not sensitivity to irradiation or temozolomide in vitro.
    Neuro-oncology, 2009, Volume: 11, Issue:6

    Topics: Animals; Antineoplastic Agents, Alkylating; bcl-X Protein; Brain Neoplasms; Cell Adhesion; Cell Move

2009
Cilengitide modulates attachment and viability of human glioma cells, but not sensitivity to irradiation or temozolomide in vitro.
    Neuro-oncology, 2009, Volume: 11, Issue:6

    Topics: Animals; Antineoplastic Agents, Alkylating; bcl-X Protein; Brain Neoplasms; Cell Adhesion; Cell Move

2009
Treg depletion with a low-dose metronomic temozolomide regimen in a rat glioma model.
    Cancer immunology, immunotherapy : CII, 2009, Volume: 58, Issue:10

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Dose-Response Relationship

2009
Treg depletion with a low-dose metronomic temozolomide regimen in a rat glioma model.
    Cancer immunology, immunotherapy : CII, 2009, Volume: 58, Issue:10

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Dose-Response Relationship

2009
Treg depletion with a low-dose metronomic temozolomide regimen in a rat glioma model.
    Cancer immunology, immunotherapy : CII, 2009, Volume: 58, Issue:10

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Dose-Response Relationship

2009
Effect of adding temozolomide to radiation therapy on the incidence of pseudo-progression.
    Journal of neuro-oncology, 2009, Volume: 94, Issue:1

    Topics: Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Di

2009
Effect of adding temozolomide to radiation therapy on the incidence of pseudo-progression.
    Journal of neuro-oncology, 2009, Volume: 94, Issue:1

    Topics: Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Di

2009
Effect of adding temozolomide to radiation therapy on the incidence of pseudo-progression.
    Journal of neuro-oncology, 2009, Volume: 94, Issue:1

    Topics: Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Di

2009
Valproic acid related idiosyncratic drug induced hepatotoxicity in a glioblastoma patient treated with temozolomide.
    Acta neurologica Belgica, 2008, Volume: 108, Issue:4

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemical and Drug Induced Liver Injury; Chemothe

2008
Valproic acid related idiosyncratic drug induced hepatotoxicity in a glioblastoma patient treated with temozolomide.
    Acta neurologica Belgica, 2008, Volume: 108, Issue:4

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemical and Drug Induced Liver Injury; Chemothe

2008
Valproic acid related idiosyncratic drug induced hepatotoxicity in a glioblastoma patient treated with temozolomide.
    Acta neurologica Belgica, 2008, Volume: 108, Issue:4

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemical and Drug Induced Liver Injury; Chemothe

2008
Rechallenge with temozolomide in patients with recurrent gliomas.
    Journal of neurology, 2009, Volume: 256, Issue:5

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain; Brain Neoplasms; Cohort Studies; Dacarbazine;

2009
Rechallenge with temozolomide in patients with recurrent gliomas.
    Journal of neurology, 2009, Volume: 256, Issue:5

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain; Brain Neoplasms; Cohort Studies; Dacarbazine;

2009
Rechallenge with temozolomide in patients with recurrent gliomas.
    Journal of neurology, 2009, Volume: 256, Issue:5

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain; Brain Neoplasms; Cohort Studies; Dacarbazine;

2009
MSH6 inactivation and emergent temozolomide resistance in human glioblastomas.
    Clinical neurosurgery, 2008, Volume: 55

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant; Dacarbazine; Disease Pro

2008
MSH6 inactivation and emergent temozolomide resistance in human glioblastomas.
    Clinical neurosurgery, 2008, Volume: 55

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant; Dacarbazine; Disease Pro

2008
MSH6 inactivation and emergent temozolomide resistance in human glioblastomas.
    Clinical neurosurgery, 2008, Volume: 55

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant; Dacarbazine; Disease Pro

2008
The side story of stem-like glioma cells.
    Cell stem cell, 2009, Mar-06, Volume: 4, Issue:3

    Topics: Animals; Antineoplastic Agents, Alkylating; ATP Binding Cassette Transporter, Subfamily G, Member 2;

2009
The side story of stem-like glioma cells.
    Cell stem cell, 2009, Mar-06, Volume: 4, Issue:3

    Topics: Animals; Antineoplastic Agents, Alkylating; ATP Binding Cassette Transporter, Subfamily G, Member 2;

2009
The side story of stem-like glioma cells.
    Cell stem cell, 2009, Mar-06, Volume: 4, Issue:3

    Topics: Animals; Antineoplastic Agents, Alkylating; ATP Binding Cassette Transporter, Subfamily G, Member 2;

2009
Management of temozolomide toxicity by nurse practitioners in neuro-oncology.
    Oncology nursing forum, 2009, Volume: 36, Issue:2

    Topics: Analysis of Variance; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chi-Square Distribution; D

2009
Management of temozolomide toxicity by nurse practitioners in neuro-oncology.
    Oncology nursing forum, 2009, Volume: 36, Issue:2

    Topics: Analysis of Variance; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chi-Square Distribution; D

2009
Management of temozolomide toxicity by nurse practitioners in neuro-oncology.
    Oncology nursing forum, 2009, Volume: 36, Issue:2

    Topics: Analysis of Variance; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chi-Square Distribution; D

2009
Homogeneous MGMT immunoreactivity correlates with an unmethylated MGMT promoter status in brain metastases of various solid tumors.
    PloS one, 2009, Volume: 4, Issue:3

    Topics: Alkylating Agents; Brain Neoplasms; Breast Neoplasms; Dacarbazine; DNA Methylation; DNA Modification

2009
Homogeneous MGMT immunoreactivity correlates with an unmethylated MGMT promoter status in brain metastases of various solid tumors.
    PloS one, 2009, Volume: 4, Issue:3

    Topics: Alkylating Agents; Brain Neoplasms; Breast Neoplasms; Dacarbazine; DNA Methylation; DNA Modification

2009
Homogeneous MGMT immunoreactivity correlates with an unmethylated MGMT promoter status in brain metastases of various solid tumors.
    PloS one, 2009, Volume: 4, Issue:3

    Topics: Alkylating Agents; Brain Neoplasms; Breast Neoplasms; Dacarbazine; DNA Methylation; DNA Modification

2009
Pathologic correlates of primary central nervous system lymphoma defined in an orthotopic xenograft model.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2009, Mar-15, Volume: 15, Issue:6

    Topics: Animals; Brain Neoplasms; Cell Polarity; Dacarbazine; DNA Modification Methylases; DNA Repair Enzyme

2009
Pathologic correlates of primary central nervous system lymphoma defined in an orthotopic xenograft model.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2009, Mar-15, Volume: 15, Issue:6

    Topics: Animals; Brain Neoplasms; Cell Polarity; Dacarbazine; DNA Modification Methylases; DNA Repair Enzyme

2009
Pathologic correlates of primary central nervous system lymphoma defined in an orthotopic xenograft model.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2009, Mar-15, Volume: 15, Issue:6

    Topics: Animals; Brain Neoplasms; Cell Polarity; Dacarbazine; DNA Modification Methylases; DNA Repair Enzyme

2009
Combination of adenoviral virotherapy and temozolomide chemotherapy eradicates malignant glioma through autophagic and apoptotic cell death in vivo.
    British journal of cancer, 2009, Apr-07, Volume: 100, Issue:7

    Topics: Adenoviridae; Animals; Antineoplastic Agents, Alkylating; Apoptosis; Autophagy; Brain Neoplasms; Cas

2009
Combination of adenoviral virotherapy and temozolomide chemotherapy eradicates malignant glioma through autophagic and apoptotic cell death in vivo.
    British journal of cancer, 2009, Apr-07, Volume: 100, Issue:7

    Topics: Adenoviridae; Animals; Antineoplastic Agents, Alkylating; Apoptosis; Autophagy; Brain Neoplasms; Cas

2009
Combination of adenoviral virotherapy and temozolomide chemotherapy eradicates malignant glioma through autophagic and apoptotic cell death in vivo.
    British journal of cancer, 2009, Apr-07, Volume: 100, Issue:7

    Topics: Adenoviridae; Animals; Antineoplastic Agents, Alkylating; Apoptosis; Autophagy; Brain Neoplasms; Cas

2009
Long-term use of temozolomide: could you use temozolomide safely for life in gliomas?
    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2009, Volume: 16, Issue:6

    Topics: Adolescent; Adult; Antineoplastic Agents, Alkylating; Astrocytoma; Brain; Brain Neoplasms; Dacarbazi

2009
Long-term use of temozolomide: could you use temozolomide safely for life in gliomas?
    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2009, Volume: 16, Issue:6

    Topics: Adolescent; Adult; Antineoplastic Agents, Alkylating; Astrocytoma; Brain; Brain Neoplasms; Dacarbazi

2009
Long-term use of temozolomide: could you use temozolomide safely for life in gliomas?
    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2009, Volume: 16, Issue:6

    Topics: Adolescent; Adult; Antineoplastic Agents, Alkylating; Astrocytoma; Brain; Brain Neoplasms; Dacarbazi

2009
Delivery of temozolomide to the tumor bed via biodegradable gel matrices in a novel model of intracranial glioma with resection.
    Journal of neuro-oncology, 2009, Volume: 94, Issue:2

    Topics: Animals; Antineoplastic Agents, Alkylating; Biocompatible Materials; Brain; Brain Neoplasms; Combine

2009
Delivery of temozolomide to the tumor bed via biodegradable gel matrices in a novel model of intracranial glioma with resection.
    Journal of neuro-oncology, 2009, Volume: 94, Issue:2

    Topics: Animals; Antineoplastic Agents, Alkylating; Biocompatible Materials; Brain; Brain Neoplasms; Combine

2009
Delivery of temozolomide to the tumor bed via biodegradable gel matrices in a novel model of intracranial glioma with resection.
    Journal of neuro-oncology, 2009, Volume: 94, Issue:2

    Topics: Animals; Antineoplastic Agents, Alkylating; Biocompatible Materials; Brain; Brain Neoplasms; Combine

2009
Cytomegalovirus associated colonic pseudotumor: a consequence of iatrogenic immunosuppression in a patient with primary brain tumor receiving radiation and temozolomide.
    Journal of neuro-oncology, 2009, Volume: 94, Issue:3

    Topics: Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cytomegalovirus Infections; Dacarbazine; F

2009
Cytomegalovirus associated colonic pseudotumor: a consequence of iatrogenic immunosuppression in a patient with primary brain tumor receiving radiation and temozolomide.
    Journal of neuro-oncology, 2009, Volume: 94, Issue:3

    Topics: Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cytomegalovirus Infections; Dacarbazine; F

2009
Cytomegalovirus associated colonic pseudotumor: a consequence of iatrogenic immunosuppression in a patient with primary brain tumor receiving radiation and temozolomide.
    Journal of neuro-oncology, 2009, Volume: 94, Issue:3

    Topics: Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cytomegalovirus Infections; Dacarbazine; F

2009
CRAdRGDflt-IL24 virotherapy in combination with chemotherapy of experimental glioma.
    Cancer gene therapy, 2009, Volume: 16, Issue:10

    Topics: Adenoviridae; Animals; Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cell Growth Pr

2009
CRAdRGDflt-IL24 virotherapy in combination with chemotherapy of experimental glioma.
    Cancer gene therapy, 2009, Volume: 16, Issue:10

    Topics: Adenoviridae; Animals; Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cell Growth Pr

2009
CRAdRGDflt-IL24 virotherapy in combination with chemotherapy of experimental glioma.
    Cancer gene therapy, 2009, Volume: 16, Issue:10

    Topics: Adenoviridae; Animals; Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cell Growth Pr

2009
[Research and therapeutic trials on gliomas].
    Soins; la revue de reference infirmiere, 2009, Issue:733

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Clinical Trials as Topic; Combined Modality Ther

2009
[Research and therapeutic trials on gliomas].
    Soins; la revue de reference infirmiere, 2009, Issue:733

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Clinical Trials as Topic; Combined Modality Ther

2009
[Research and therapeutic trials on gliomas].
    Soins; la revue de reference infirmiere, 2009, Issue:733

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Clinical Trials as Topic; Combined Modality Ther

2009
Glioma-associated endothelial cells are chemoresistant to temozolomide.
    Journal of neuro-oncology, 2009, Volume: 95, Issue:1

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Death; Cell Movement; Cell Prolife

2009
Glioma-associated endothelial cells are chemoresistant to temozolomide.
    Journal of neuro-oncology, 2009, Volume: 95, Issue:1

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Death; Cell Movement; Cell Prolife

2009
Glioma-associated endothelial cells are chemoresistant to temozolomide.
    Journal of neuro-oncology, 2009, Volume: 95, Issue:1

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Death; Cell Movement; Cell Prolife

2009
Preradiation chemotherapy with ACNU-CDDP in patients with newly diagnosed glioblastoma: a retrospective analysis.
    Chemotherapy, 2009, Volume: 55, Issue:3

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Chemothera

2009
Preradiation chemotherapy with ACNU-CDDP in patients with newly diagnosed glioblastoma: a retrospective analysis.
    Chemotherapy, 2009, Volume: 55, Issue:3

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Chemothera

2009
Preradiation chemotherapy with ACNU-CDDP in patients with newly diagnosed glioblastoma: a retrospective analysis.
    Chemotherapy, 2009, Volume: 55, Issue:3

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Chemothera

2009
IgE, allergy, and risk of glioma: update from the San Francisco Bay Area Adult Glioma Study in the temozolomide era.
    International journal of cancer, 2009, Aug-01, Volume: 125, Issue:3

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Case-Control Studies; Confounding F

2009
IgE, allergy, and risk of glioma: update from the San Francisco Bay Area Adult Glioma Study in the temozolomide era.
    International journal of cancer, 2009, Aug-01, Volume: 125, Issue:3

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Case-Control Studies; Confounding F

2009
IgE, allergy, and risk of glioma: update from the San Francisco Bay Area Adult Glioma Study in the temozolomide era.
    International journal of cancer, 2009, Aug-01, Volume: 125, Issue:3

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Case-Control Studies; Confounding F

2009
Efficacy of temozolomide treatment in patients with high-grade glioma.
    Anticancer research, 2009, Volume: 29, Issue:3

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carboplatin; Chemother

2009
Efficacy of temozolomide treatment in patients with high-grade glioma.
    Anticancer research, 2009, Volume: 29, Issue:3

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carboplatin; Chemother

2009
Efficacy of temozolomide treatment in patients with high-grade glioma.
    Anticancer research, 2009, Volume: 29, Issue:3

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carboplatin; Chemother

2009
EGFRvIII and DNA double-strand break repair: a molecular mechanism for radioresistance in glioblastoma.
    Cancer research, 2009, May-15, Volume: 69, Issue:10

    Topics: Animals; Astrocytes; Brain Neoplasms; Cell Line, Tumor; Combined Modality Therapy; Dacarbazine; DNA

2009
EGFRvIII and DNA double-strand break repair: a molecular mechanism for radioresistance in glioblastoma.
    Cancer research, 2009, May-15, Volume: 69, Issue:10

    Topics: Animals; Astrocytes; Brain Neoplasms; Cell Line, Tumor; Combined Modality Therapy; Dacarbazine; DNA

2009
EGFRvIII and DNA double-strand break repair: a molecular mechanism for radioresistance in glioblastoma.
    Cancer research, 2009, May-15, Volume: 69, Issue:10

    Topics: Animals; Astrocytes; Brain Neoplasms; Cell Line, Tumor; Combined Modality Therapy; Dacarbazine; DNA

2009
Induction of oligodendrogenesis in glioblastoma-initiating cells by IFN-mediated activation of STAT3 signaling.
    Cancer letters, 2009, Oct-18, Volume: 284, Issue:1

    Topics: Antineoplastic Agents; Brain Neoplasms; Cell Differentiation; Cell Line, Tumor; Dacarbazine; Drug Re

2009
Induction of oligodendrogenesis in glioblastoma-initiating cells by IFN-mediated activation of STAT3 signaling.
    Cancer letters, 2009, Oct-18, Volume: 284, Issue:1

    Topics: Antineoplastic Agents; Brain Neoplasms; Cell Differentiation; Cell Line, Tumor; Dacarbazine; Drug Re

2009
Induction of oligodendrogenesis in glioblastoma-initiating cells by IFN-mediated activation of STAT3 signaling.
    Cancer letters, 2009, Oct-18, Volume: 284, Issue:1

    Topics: Antineoplastic Agents; Brain Neoplasms; Cell Differentiation; Cell Line, Tumor; Dacarbazine; Drug Re

2009
Stevens-Johnson Syndrome and toxic epidermal necrolysis overlap due to oral temozolomide and cranial radiotherapy.
    American journal of clinical dermatology, 2009, Volume: 10, Issue:4

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Glioblas

2009
Stevens-Johnson Syndrome and toxic epidermal necrolysis overlap due to oral temozolomide and cranial radiotherapy.
    American journal of clinical dermatology, 2009, Volume: 10, Issue:4

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Glioblas

2009
Stevens-Johnson Syndrome and toxic epidermal necrolysis overlap due to oral temozolomide and cranial radiotherapy.
    American journal of clinical dermatology, 2009, Volume: 10, Issue:4

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Glioblas

2009
Effect of IFN-beta on human glioma cell lines with temozolomide resistance.
    International journal of oncology, 2009, Volume: 35, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms;

2009
Effect of IFN-beta on human glioma cell lines with temozolomide resistance.
    International journal of oncology, 2009, Volume: 35, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms;

2009
Effect of IFN-beta on human glioma cell lines with temozolomide resistance.
    International journal of oncology, 2009, Volume: 35, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms;

2009
Overall survival of newly diagnosed glioblastoma patients receiving carmustine wafers followed by radiation and concurrent temozolomide plus rotational multiagent chemotherapy.
    Cancer, 2009, Aug-01, Volume: 115, Issue:15

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carmustine; Combined M

2009
Overall survival of newly diagnosed glioblastoma patients receiving carmustine wafers followed by radiation and concurrent temozolomide plus rotational multiagent chemotherapy.
    Cancer, 2009, Aug-01, Volume: 115, Issue:15

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carmustine; Combined M

2009
Overall survival of newly diagnosed glioblastoma patients receiving carmustine wafers followed by radiation and concurrent temozolomide plus rotational multiagent chemotherapy.
    Cancer, 2009, Aug-01, Volume: 115, Issue:15

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carmustine; Combined M

2009
Temozolomide concomitant and adjuvant to radiotherapy in elderly patients with glioblastoma: correlation with MGMT promoter methylation status.
    Cancer, 2009, Aug-01, Volume: 115, Issue:15

    Topics: Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant; Combined Modality

2009
Temozolomide concomitant and adjuvant to radiotherapy in elderly patients with glioblastoma: correlation with MGMT promoter methylation status.
    Cancer, 2009, Aug-01, Volume: 115, Issue:15

    Topics: Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant; Combined Modality

2009
Temozolomide concomitant and adjuvant to radiotherapy in elderly patients with glioblastoma: correlation with MGMT promoter methylation status.
    Cancer, 2009, Aug-01, Volume: 115, Issue:15

    Topics: Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant; Combined Modality

2009
Inhibition of c-Jun N-terminal kinase enhances temozolomide-induced cytotoxicity in human glioma cells.
    Journal of neuro-oncology, 2009, Volume: 95, Issue:3

    Topics: Activating Transcription Factor 2; Anthracenes; Antineoplastic Agents, Alkylating; beta-Galactosidas

2009
Inhibition of c-Jun N-terminal kinase enhances temozolomide-induced cytotoxicity in human glioma cells.
    Journal of neuro-oncology, 2009, Volume: 95, Issue:3

    Topics: Activating Transcription Factor 2; Anthracenes; Antineoplastic Agents, Alkylating; beta-Galactosidas

2009
Inhibition of c-Jun N-terminal kinase enhances temozolomide-induced cytotoxicity in human glioma cells.
    Journal of neuro-oncology, 2009, Volume: 95, Issue:3

    Topics: Activating Transcription Factor 2; Anthracenes; Antineoplastic Agents, Alkylating; beta-Galactosidas

2009
Extent of MGMT promoter methylation correlates with outcome in glioblastomas given temozolomide and radiotherapy.
    British journal of cancer, 2009, Jul-07, Volume: 101, Issue:1

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Chemo

2009
Extent of MGMT promoter methylation correlates with outcome in glioblastomas given temozolomide and radiotherapy.
    British journal of cancer, 2009, Jul-07, Volume: 101, Issue:1

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Chemo

2009
Extent of MGMT promoter methylation correlates with outcome in glioblastomas given temozolomide and radiotherapy.
    British journal of cancer, 2009, Jul-07, Volume: 101, Issue:1

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Chemo

2009
Combined modality treatment of newly diagnosed glioblastoma multiforme in a regional neurosurgical centre.
    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2009, Volume: 16, Issue:9

    Topics: Adrenal Cortex Hormones; Adult; Aged; Anticonvulsants; Antineoplastic Agents, Alkylating; Brain Neop

2009
Combined modality treatment of newly diagnosed glioblastoma multiforme in a regional neurosurgical centre.
    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2009, Volume: 16, Issue:9

    Topics: Adrenal Cortex Hormones; Adult; Aged; Anticonvulsants; Antineoplastic Agents, Alkylating; Brain Neop

2009
Combined modality treatment of newly diagnosed glioblastoma multiforme in a regional neurosurgical centre.
    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2009, Volume: 16, Issue:9

    Topics: Adrenal Cortex Hormones; Adult; Aged; Anticonvulsants; Antineoplastic Agents, Alkylating; Brain Neop

2009
The prognostic role of Beclin 1 protein expression in high-grade gliomas.
    Autophagy, 2009, Volume: 5, Issue:7

    Topics: Antineoplastic Agents, Alkylating; Apoptosis Regulatory Proteins; Autophagy; Beclin-1; Biomarkers, T

2009
The prognostic role of Beclin 1 protein expression in high-grade gliomas.
    Autophagy, 2009, Volume: 5, Issue:7

    Topics: Antineoplastic Agents, Alkylating; Apoptosis Regulatory Proteins; Autophagy; Beclin-1; Biomarkers, T

2009
The prognostic role of Beclin 1 protein expression in high-grade gliomas.
    Autophagy, 2009, Volume: 5, Issue:7

    Topics: Antineoplastic Agents, Alkylating; Apoptosis Regulatory Proteins; Autophagy; Beclin-1; Biomarkers, T

2009
[Central nervous system glioma. Multi-drug chemotherapy including temozolomide].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2009, Volume: 36, Issue:6

    Topics: Antineoplastic Agents; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Proto

2009
[Central nervous system glioma. Multi-drug chemotherapy including temozolomide].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2009, Volume: 36, Issue:6

    Topics: Antineoplastic Agents; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Proto

2009
[Central nervous system glioma. Multi-drug chemotherapy including temozolomide].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2009, Volume: 36, Issue:6

    Topics: Antineoplastic Agents; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Proto

2009
FEN1 is overexpressed in testis, lung and brain tumors.
    Anticancer research, 2009, Volume: 29, Issue:7

    Topics: Antineoplastic Agents; Apoptosis; Base Sequence; Brain Neoplasms; Cisplatin; Dacarbazine; Flap Endon

2009
FEN1 is overexpressed in testis, lung and brain tumors.
    Anticancer research, 2009, Volume: 29, Issue:7

    Topics: Antineoplastic Agents; Apoptosis; Base Sequence; Brain Neoplasms; Cisplatin; Dacarbazine; Flap Endon

2009
FEN1 is overexpressed in testis, lung and brain tumors.
    Anticancer research, 2009, Volume: 29, Issue:7

    Topics: Antineoplastic Agents; Apoptosis; Base Sequence; Brain Neoplasms; Cisplatin; Dacarbazine; Flap Endon

2009
Pseudoprogression and MGMT status in glioblastoma patients: implications in clinical practice.
    Anticancer research, 2009, Volume: 29, Issue:7

    Topics: Aged; Antineoplastic Agents; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease Progre

2009
Pseudoprogression and MGMT status in glioblastoma patients: implications in clinical practice.
    Anticancer research, 2009, Volume: 29, Issue:7

    Topics: Aged; Antineoplastic Agents; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease Progre

2009
Pseudoprogression and MGMT status in glioblastoma patients: implications in clinical practice.
    Anticancer research, 2009, Volume: 29, Issue:7

    Topics: Aged; Antineoplastic Agents; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease Progre

2009
Comparing neuropsychological tasks to optimize brief cognitive batteries for brain tumor clinical trials.
    Journal of neuro-oncology, 2010, Volume: 96, Issue:2

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Attention; Brain Neoplasms; Cognition Disorders; Dac

2010
Comparing neuropsychological tasks to optimize brief cognitive batteries for brain tumor clinical trials.
    Journal of neuro-oncology, 2010, Volume: 96, Issue:2

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Attention; Brain Neoplasms; Cognition Disorders; Dac

2010
Comparing neuropsychological tasks to optimize brief cognitive batteries for brain tumor clinical trials.
    Journal of neuro-oncology, 2010, Volume: 96, Issue:2

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Attention; Brain Neoplasms; Cognition Disorders; Dac

2010
Comment re: Temozolomide preferentially depletes cancer stem cells.
    Cancer research, 2009, Aug-01, Volume: 69, Issue:15

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Glioblastoma; Humans; Magnetic Reso

2009
Comment re: Temozolomide preferentially depletes cancer stem cells.
    Cancer research, 2009, Aug-01, Volume: 69, Issue:15

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Glioblastoma; Humans; Magnetic Reso

2009
Comment re: Temozolomide preferentially depletes cancer stem cells.
    Cancer research, 2009, Aug-01, Volume: 69, Issue:15

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Glioblastoma; Humans; Magnetic Reso

2009
[Detection of O6-methylguanine-DNA methyltransferase promoter methylation in chemotherapy for glioma].
    Ai zheng = Aizheng = Chinese journal of cancer, 2009, Volume: 28, Issue:6

    Topics: Adolescent; Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Agents, Alkylating; Azaciti

2009
[Detection of O6-methylguanine-DNA methyltransferase promoter methylation in chemotherapy for glioma].
    Ai zheng = Aizheng = Chinese journal of cancer, 2009, Volume: 28, Issue:6

    Topics: Adolescent; Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Agents, Alkylating; Azaciti

2009
[Detection of O6-methylguanine-DNA methyltransferase promoter methylation in chemotherapy for glioma].
    Ai zheng = Aizheng = Chinese journal of cancer, 2009, Volume: 28, Issue:6

    Topics: Adolescent; Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Agents, Alkylating; Azaciti

2009
Perioperative high-dose-rate brachytherapy in the treatment of recurrent malignant gliomas.
    Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 2009, Volume: 185, Issue:8

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Astrocytoma; Brachytherapy; Brain Neoplasms; Chemoth

2009
Perioperative high-dose-rate brachytherapy in the treatment of recurrent malignant gliomas.
    Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 2009, Volume: 185, Issue:8

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Astrocytoma; Brachytherapy; Brain Neoplasms; Chemoth

2009
Perioperative high-dose-rate brachytherapy in the treatment of recurrent malignant gliomas.
    Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 2009, Volume: 185, Issue:8

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Astrocytoma; Brachytherapy; Brain Neoplasms; Chemoth

2009
Methionine restriction reduces the chemosensitivity of central nervous system tumour cell lines.
    Anticancer research, 2009, Volume: 29, Issue:8

    Topics: Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Cell Proliferation; Cerebellar Neop

2009
Methionine restriction reduces the chemosensitivity of central nervous system tumour cell lines.
    Anticancer research, 2009, Volume: 29, Issue:8

    Topics: Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Cell Proliferation; Cerebellar Neop

2009
Methionine restriction reduces the chemosensitivity of central nervous system tumour cell lines.
    Anticancer research, 2009, Volume: 29, Issue:8

    Topics: Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Cell Proliferation; Cerebellar Neop

2009
Radiosensitizing effects of temozolomide observed in vivo only in a subset of O6-methylguanine-DNA methyltransferase methylated glioblastoma multiforme xenografts.
    International journal of radiation oncology, biology, physics, 2009, Sep-01, Volume: 75, Issue:1

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Combined Modality The

2009
Radiosensitizing effects of temozolomide observed in vivo only in a subset of O6-methylguanine-DNA methyltransferase methylated glioblastoma multiforme xenografts.
    International journal of radiation oncology, biology, physics, 2009, Sep-01, Volume: 75, Issue:1

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Combined Modality The

2009
Radiosensitizing effects of temozolomide observed in vivo only in a subset of O6-methylguanine-DNA methyltransferase methylated glioblastoma multiforme xenografts.
    International journal of radiation oncology, biology, physics, 2009, Sep-01, Volume: 75, Issue:1

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Combined Modality The

2009
Prognostic and predictive value of p53 in low MGMT expressing glioblastoma treated with surgery, radiation and adjuvant temozolomide chemotherapy.
    Neurological research, 2010, Volume: 32, Issue:7

    Topics: Brain Neoplasms; Chemotherapy, Adjuvant; Combined Modality Therapy; Dacarbazine; Disease-Free Surviv

2010
Prognostic and predictive value of p53 in low MGMT expressing glioblastoma treated with surgery, radiation and adjuvant temozolomide chemotherapy.
    Neurological research, 2010, Volume: 32, Issue:7

    Topics: Brain Neoplasms; Chemotherapy, Adjuvant; Combined Modality Therapy; Dacarbazine; Disease-Free Surviv

2010
Prognostic and predictive value of p53 in low MGMT expressing glioblastoma treated with surgery, radiation and adjuvant temozolomide chemotherapy.
    Neurological research, 2010, Volume: 32, Issue:7

    Topics: Brain Neoplasms; Chemotherapy, Adjuvant; Combined Modality Therapy; Dacarbazine; Disease-Free Surviv

2010
Efficacy of temozolomide as adjuvant chemotherapy after postsurgical radiotherapy alone for glioblastomas.
    Clinical neurology and neurosurgery, 2009, Volume: 111, Issue:9

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Case-Control Studies; C

2009
Efficacy of temozolomide as adjuvant chemotherapy after postsurgical radiotherapy alone for glioblastomas.
    Clinical neurology and neurosurgery, 2009, Volume: 111, Issue:9

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Case-Control Studies; C

2009
Efficacy of temozolomide as adjuvant chemotherapy after postsurgical radiotherapy alone for glioblastomas.
    Clinical neurology and neurosurgery, 2009, Volume: 111, Issue:9

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Case-Control Studies; C

2009
Cognitive functioning in glioblastoma patients during radiotherapy and temozolomide treatment: initial findings.
    Journal of neuro-oncology, 2010, Volume: 97, Issue:1

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Attention; Brain Neoplasms; Cognition Di

2010
Cognitive functioning in glioblastoma patients during radiotherapy and temozolomide treatment: initial findings.
    Journal of neuro-oncology, 2010, Volume: 97, Issue:1

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Attention; Brain Neoplasms; Cognition Di

2010
Cognitive functioning in glioblastoma patients during radiotherapy and temozolomide treatment: initial findings.
    Journal of neuro-oncology, 2010, Volume: 97, Issue:1

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Attention; Brain Neoplasms; Cognition Di

2010
Modulation of KCa channels increases anticancer drug delivery to brain tumors and prolongs survival in xenograft model.
    Cancer biology & therapy, 2009, Volume: 8, Issue:20

    Topics: Animals; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Antineopl

2009
Modulation of KCa channels increases anticancer drug delivery to brain tumors and prolongs survival in xenograft model.
    Cancer biology & therapy, 2009, Volume: 8, Issue:20

    Topics: Animals; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Antineopl

2009
Modulation of KCa channels increases anticancer drug delivery to brain tumors and prolongs survival in xenograft model.
    Cancer biology & therapy, 2009, Volume: 8, Issue:20

    Topics: Animals; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Antineopl

2009
O(6)-Methylguanine-DNA methyltransferase expression and prognostic value in brain metastases of lung cancers.
    Lung cancer (Amsterdam, Netherlands), 2010, Volume: 68, Issue:3

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms;

2010
O(6)-Methylguanine-DNA methyltransferase expression and prognostic value in brain metastases of lung cancers.
    Lung cancer (Amsterdam, Netherlands), 2010, Volume: 68, Issue:3

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms;

2010
O(6)-Methylguanine-DNA methyltransferase expression and prognostic value in brain metastases of lung cancers.
    Lung cancer (Amsterdam, Netherlands), 2010, Volume: 68, Issue:3

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms;

2010
Glioblastoma masquerading as a hypertensive putaminal hemorrhage: a diagnostic pitfall.
    Neurologia medico-chirurgica, 2009, Volume: 49, Issue:9

    Topics: Antihypertensive Agents; Antineoplastic Agents, Alkylating; Biopsy; Brain Neoplasms; Dacarbazine; Di

2009
Glioblastoma masquerading as a hypertensive putaminal hemorrhage: a diagnostic pitfall.
    Neurologia medico-chirurgica, 2009, Volume: 49, Issue:9

    Topics: Antihypertensive Agents; Antineoplastic Agents, Alkylating; Biopsy; Brain Neoplasms; Dacarbazine; Di

2009
Glioblastoma masquerading as a hypertensive putaminal hemorrhage: a diagnostic pitfall.
    Neurologia medico-chirurgica, 2009, Volume: 49, Issue:9

    Topics: Antihypertensive Agents; Antineoplastic Agents, Alkylating; Biopsy; Brain Neoplasms; Dacarbazine; Di

2009
Secondary gliosarcoma after diagnosis of glioblastoma: clinical experience with 30 consecutive patients.
    Journal of neurosurgery, 2010, Volume: 112, Issue:5

    Topics: Adult; Aged; Antineoplastic Agents; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Female;

2010
Secondary gliosarcoma after diagnosis of glioblastoma: clinical experience with 30 consecutive patients.
    Journal of neurosurgery, 2010, Volume: 112, Issue:5

    Topics: Adult; Aged; Antineoplastic Agents; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Female;

2010
Secondary gliosarcoma after diagnosis of glioblastoma: clinical experience with 30 consecutive patients.
    Journal of neurosurgery, 2010, Volume: 112, Issue:5

    Topics: Adult; Aged; Antineoplastic Agents; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Female;

2010
Concurrent temozolomide and radiation, a reasonable option for elderly patients with glioblastoma multiforme?
    American journal of clinical oncology, 2010, Volume: 33, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modalit

2010
Concurrent temozolomide and radiation, a reasonable option for elderly patients with glioblastoma multiforme?
    American journal of clinical oncology, 2010, Volume: 33, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modalit

2010
Concurrent temozolomide and radiation, a reasonable option for elderly patients with glioblastoma multiforme?
    American journal of clinical oncology, 2010, Volume: 33, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modalit

2010
Recurrent glioblastoma of childhood treated with bevacizumab: case report and molecular features.
    Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 2010, Volume: 26, Issue:1

    Topics: Adolescent; Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Anti

2010
Recurrent glioblastoma of childhood treated with bevacizumab: case report and molecular features.
    Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 2010, Volume: 26, Issue:1

    Topics: Adolescent; Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Anti

2010
Recurrent glioblastoma of childhood treated with bevacizumab: case report and molecular features.
    Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 2010, Volume: 26, Issue:1

    Topics: Adolescent; Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Anti

2010
Recurrent PNET with MGMT methylation responds to temozolomide.
    The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques, 2009, Volume: 36, Issue:5

    Topics: Adult; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Humans; Magnetic Resonance I

2009
Recurrent PNET with MGMT methylation responds to temozolomide.
    The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques, 2009, Volume: 36, Issue:5

    Topics: Adult; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Humans; Magnetic Resonance I

2009
Recurrent PNET with MGMT methylation responds to temozolomide.
    The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques, 2009, Volume: 36, Issue:5

    Topics: Adult; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Humans; Magnetic Resonance I

2009
The correlation and prognostic significance of MGMT promoter methylation and MGMT protein in glioblastomas.
    Neurosurgery, 2009, Volume: 65, Issue:5

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Thera

2009
The correlation and prognostic significance of MGMT promoter methylation and MGMT protein in glioblastomas.
    Neurosurgery, 2009, Volume: 65, Issue:5

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Thera

2009
The correlation and prognostic significance of MGMT promoter methylation and MGMT protein in glioblastomas.
    Neurosurgery, 2009, Volume: 65, Issue:5

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Thera

2009
A mathematical model of brain tumour response to radiotherapy and chemotherapy considering radiobiological aspects.
    Journal of theoretical biology, 2010, Feb-07, Volume: 262, Issue:3

    Topics: Antineoplastic Agents; Brain Neoplasms; Cell Proliferation; Dacarbazine; Dose-Response Relationship,

2010
A mathematical model of brain tumour response to radiotherapy and chemotherapy considering radiobiological aspects.
    Journal of theoretical biology, 2010, Feb-07, Volume: 262, Issue:3

    Topics: Antineoplastic Agents; Brain Neoplasms; Cell Proliferation; Dacarbazine; Dose-Response Relationship,

2010
A mathematical model of brain tumour response to radiotherapy and chemotherapy considering radiobiological aspects.
    Journal of theoretical biology, 2010, Feb-07, Volume: 262, Issue:3

    Topics: Antineoplastic Agents; Brain Neoplasms; Cell Proliferation; Dacarbazine; Dose-Response Relationship,

2010
Inter- and intrapatients comparison of WHO grade II glioma kinetics before and after surgical resection.
    Neurosurgical review, 2010, Volume: 33, Issue:1

    Topics: Adolescent; Adult; Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neoplasms; Child; Dacarbazi

2010
Inter- and intrapatients comparison of WHO grade II glioma kinetics before and after surgical resection.
    Neurosurgical review, 2010, Volume: 33, Issue:1

    Topics: Adolescent; Adult; Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neoplasms; Child; Dacarbazi

2010
Inter- and intrapatients comparison of WHO grade II glioma kinetics before and after surgical resection.
    Neurosurgical review, 2010, Volume: 33, Issue:1

    Topics: Adolescent; Adult; Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neoplasms; Child; Dacarbazi

2010
Intrathecal liposomal cytarabine in combination with temozolomide in low-grade oligoastrocytoma with leptomeningeal dissemination.
    Journal of neuro-oncology, 2010, Volume: 97, Issue:3

    Topics: Adult; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Cytar

2010
Intrathecal liposomal cytarabine in combination with temozolomide in low-grade oligoastrocytoma with leptomeningeal dissemination.
    Journal of neuro-oncology, 2010, Volume: 97, Issue:3

    Topics: Adult; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Cytar

2010
Intrathecal liposomal cytarabine in combination with temozolomide in low-grade oligoastrocytoma with leptomeningeal dissemination.
    Journal of neuro-oncology, 2010, Volume: 97, Issue:3

    Topics: Adult; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Cytar

2010
Therapy-related myelodysplastic syndrome/acute myeloid leukemia after treatment with temozolomide in a patient with glioblastoma multiforme.
    Annals of clinical and laboratory science, 2009,Fall, Volume: 39, Issue:4

    Topics: Adult; Aged; Biopsy; Bone Marrow Cells; Brain Neoplasms; Dacarbazine; Disease Progression; Female; G

2009
Therapy-related myelodysplastic syndrome/acute myeloid leukemia after treatment with temozolomide in a patient with glioblastoma multiforme.
    Annals of clinical and laboratory science, 2009,Fall, Volume: 39, Issue:4

    Topics: Adult; Aged; Biopsy; Bone Marrow Cells; Brain Neoplasms; Dacarbazine; Disease Progression; Female; G

2009
Therapy-related myelodysplastic syndrome/acute myeloid leukemia after treatment with temozolomide in a patient with glioblastoma multiforme.
    Annals of clinical and laboratory science, 2009,Fall, Volume: 39, Issue:4

    Topics: Adult; Aged; Biopsy; Bone Marrow Cells; Brain Neoplasms; Dacarbazine; Disease Progression; Female; G

2009
Immunological factors relating to the antitumor effect of temozolomide chemoimmunotherapy in a murine glioma model.
    Clinical and vaccine immunology : CVI, 2010, Volume: 17, Issue:1

    Topics: Animals; Antineoplastic Agents; Brain Neoplasms; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocy

2010
Immunological factors relating to the antitumor effect of temozolomide chemoimmunotherapy in a murine glioma model.
    Clinical and vaccine immunology : CVI, 2010, Volume: 17, Issue:1

    Topics: Animals; Antineoplastic Agents; Brain Neoplasms; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocy

2010
Immunological factors relating to the antitumor effect of temozolomide chemoimmunotherapy in a murine glioma model.
    Clinical and vaccine immunology : CVI, 2010, Volume: 17, Issue:1

    Topics: Animals; Antineoplastic Agents; Brain Neoplasms; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocy

2010
The importance of tumor volume in the prognosis of patients with glioblastoma: comparison of computerized volumetry and geometric models.
    Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 2009, Volume: 185, Issue:11

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Camptothecin; Chemothe

2009
The importance of tumor volume in the prognosis of patients with glioblastoma: comparison of computerized volumetry and geometric models.
    Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 2009, Volume: 185, Issue:11

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Camptothecin; Chemothe

2009
The importance of tumor volume in the prognosis of patients with glioblastoma: comparison of computerized volumetry and geometric models.
    Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 2009, Volume: 185, Issue:11

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Camptothecin; Chemothe

2009
Anaplastic glioma: how to prognosticate outcome and choose a treatment strategy. [corrected].
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2009, Dec-10, Volume: 27, Issue:35

    Topics: Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms;

2009
Anaplastic glioma: how to prognosticate outcome and choose a treatment strategy. [corrected].
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2009, Dec-10, Volume: 27, Issue:35

    Topics: Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms;

2009
Anaplastic glioma: how to prognosticate outcome and choose a treatment strategy. [corrected].
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2009, Dec-10, Volume: 27, Issue:35

    Topics: Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms;

2009
Six year survival after prolonged temozolomide treatment in a 30-year-old patient with glioblastoma.
    Acta neurologica Belgica, 2009, Volume: 109, Issue:3

    Topics: Adult; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Female; Glioblastoma; Humans

2009
Six year survival after prolonged temozolomide treatment in a 30-year-old patient with glioblastoma.
    Acta neurologica Belgica, 2009, Volume: 109, Issue:3

    Topics: Adult; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Female; Glioblastoma; Humans

2009
Six year survival after prolonged temozolomide treatment in a 30-year-old patient with glioblastoma.
    Acta neurologica Belgica, 2009, Volume: 109, Issue:3

    Topics: Adult; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Female; Glioblastoma; Humans

2009
Inhibition of Y-box binding protein-1 slows the growth of glioblastoma multiforme and sensitizes to temozolomide independent O6-methylguanine-DNA methyltransferase.
    Molecular cancer therapeutics, 2009, Volume: 8, Issue:12

    Topics: Adult; Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Cell Movement;

2009
Inhibition of Y-box binding protein-1 slows the growth of glioblastoma multiforme and sensitizes to temozolomide independent O6-methylguanine-DNA methyltransferase.
    Molecular cancer therapeutics, 2009, Volume: 8, Issue:12

    Topics: Adult; Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Cell Movement;

2009
Inhibition of Y-box binding protein-1 slows the growth of glioblastoma multiforme and sensitizes to temozolomide independent O6-methylguanine-DNA methyltransferase.
    Molecular cancer therapeutics, 2009, Volume: 8, Issue:12

    Topics: Adult; Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Cell Movement;

2009
Trans-sodium crocetinate enhancing survival and glioma response on magnetic resonance imaging to radiation and temozolomide.
    Journal of neurosurgery, 2010, Volume: 113, Issue:2

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Carotenoids; Cell Line, Tumor; Combined

2010
Trans-sodium crocetinate enhancing survival and glioma response on magnetic resonance imaging to radiation and temozolomide.
    Journal of neurosurgery, 2010, Volume: 113, Issue:2

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Carotenoids; Cell Line, Tumor; Combined

2010
Trans-sodium crocetinate enhancing survival and glioma response on magnetic resonance imaging to radiation and temozolomide.
    Journal of neurosurgery, 2010, Volume: 113, Issue:2

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Carotenoids; Cell Line, Tumor; Combined

2010
Brain metastases from melanoma: is there a role for concurrent temozolomide in addition to whole brain radiation therapy?
    American journal of clinical oncology, 2010, Volume: 33, Issue:6

    Topics: Administration, Oral; Aged; Antineoplastic Agents; Brain Neoplasms; Cohort Studies; Combined Modalit

2010
Brain metastases from melanoma: is there a role for concurrent temozolomide in addition to whole brain radiation therapy?
    American journal of clinical oncology, 2010, Volume: 33, Issue:6

    Topics: Administration, Oral; Aged; Antineoplastic Agents; Brain Neoplasms; Cohort Studies; Combined Modalit

2010
Brain metastases from melanoma: is there a role for concurrent temozolomide in addition to whole brain radiation therapy?
    American journal of clinical oncology, 2010, Volume: 33, Issue:6

    Topics: Administration, Oral; Aged; Antineoplastic Agents; Brain Neoplasms; Cohort Studies; Combined Modalit

2010
Brain metastases from melanoma: is there a role for concurrent temozolomide in addition to whole brain radiation therapy?
    American journal of clinical oncology, 2010, Volume: 33, Issue:6

    Topics: Administration, Oral; Aged; Antineoplastic Agents; Brain Neoplasms; Cohort Studies; Combined Modalit

2010
Brain metastases from melanoma: is there a role for concurrent temozolomide in addition to whole brain radiation therapy?
    American journal of clinical oncology, 2010, Volume: 33, Issue:6

    Topics: Administration, Oral; Aged; Antineoplastic Agents; Brain Neoplasms; Cohort Studies; Combined Modalit

2010
Brain metastases from melanoma: is there a role for concurrent temozolomide in addition to whole brain radiation therapy?
    American journal of clinical oncology, 2010, Volume: 33, Issue:6

    Topics: Administration, Oral; Aged; Antineoplastic Agents; Brain Neoplasms; Cohort Studies; Combined Modalit

2010
Brain metastases from melanoma: is there a role for concurrent temozolomide in addition to whole brain radiation therapy?
    American journal of clinical oncology, 2010, Volume: 33, Issue:6

    Topics: Administration, Oral; Aged; Antineoplastic Agents; Brain Neoplasms; Cohort Studies; Combined Modalit

2010
Brain metastases from melanoma: is there a role for concurrent temozolomide in addition to whole brain radiation therapy?
    American journal of clinical oncology, 2010, Volume: 33, Issue:6

    Topics: Administration, Oral; Aged; Antineoplastic Agents; Brain Neoplasms; Cohort Studies; Combined Modalit

2010
Brain metastases from melanoma: is there a role for concurrent temozolomide in addition to whole brain radiation therapy?
    American journal of clinical oncology, 2010, Volume: 33, Issue:6

    Topics: Administration, Oral; Aged; Antineoplastic Agents; Brain Neoplasms; Cohort Studies; Combined Modalit

2010
Brain metastases from melanoma: is there a role for concurrent temozolomide in addition to whole brain radiation therapy?
    American journal of clinical oncology, 2010, Volume: 33, Issue:6

    Topics: Administration, Oral; Aged; Antineoplastic Agents; Brain Neoplasms; Cohort Studies; Combined Modalit

2010
Brain metastases from melanoma: is there a role for concurrent temozolomide in addition to whole brain radiation therapy?
    American journal of clinical oncology, 2010, Volume: 33, Issue:6

    Topics: Administration, Oral; Aged; Antineoplastic Agents; Brain Neoplasms; Cohort Studies; Combined Modalit

2010
Brain metastases from melanoma: is there a role for concurrent temozolomide in addition to whole brain radiation therapy?
    American journal of clinical oncology, 2010, Volume: 33, Issue:6

    Topics: Administration, Oral; Aged; Antineoplastic Agents; Brain Neoplasms; Cohort Studies; Combined Modalit

2010
Neoplastic meningitis from breast cancer: feasibility and activity of long-term intrathecal liposomal Ara-C combined with dose-dense temozolomide.
    Anticancer research, 2009, Volume: 29, Issue:12

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Breast Neoplasms; Combined M

2009
Neoplastic meningitis from breast cancer: feasibility and activity of long-term intrathecal liposomal Ara-C combined with dose-dense temozolomide.
    Anticancer research, 2009, Volume: 29, Issue:12

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Breast Neoplasms; Combined M

2009
Neoplastic meningitis from breast cancer: feasibility and activity of long-term intrathecal liposomal Ara-C combined with dose-dense temozolomide.
    Anticancer research, 2009, Volume: 29, Issue:12

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Breast Neoplasms; Combined M

2009
Clinical characteristics and outcomes for a modern series of primary gliosarcoma patients.
    Cancer, 2010, Mar-01, Volume: 116, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Ad

2010
Clinical characteristics and outcomes for a modern series of primary gliosarcoma patients.
    Cancer, 2010, Mar-01, Volume: 116, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Ad

2010
Clinical characteristics and outcomes for a modern series of primary gliosarcoma patients.
    Cancer, 2010, Mar-01, Volume: 116, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Ad

2010
Up-front temozolomide in elderly patients with glioblastoma.
    Journal of neuro-oncology, 2010, Volume: 99, Issue:1

    Topics: Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; DNA Modifi

2010
Up-front temozolomide in elderly patients with glioblastoma.
    Journal of neuro-oncology, 2010, Volume: 99, Issue:1

    Topics: Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; DNA Modifi

2010
Up-front temozolomide in elderly patients with glioblastoma.
    Journal of neuro-oncology, 2010, Volume: 99, Issue:1

    Topics: Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; DNA Modifi

2010
Bevacizumab and dose-intense temozolomide in recurrent high-grade glioma.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2010, Volume: 21, Issue:8

    Topics: Adolescent; Adult; Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanize

2010
Bevacizumab and dose-intense temozolomide in recurrent high-grade glioma.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2010, Volume: 21, Issue:8

    Topics: Adolescent; Adult; Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanize

2010
Bevacizumab and dose-intense temozolomide in recurrent high-grade glioma.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2010, Volume: 21, Issue:8

    Topics: Adolescent; Adult; Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanize

2010
Long-term temozolomide treatment induces marked amino metabolism modifications and an increase in TMZ sensitivity in Hs683 oligodendroglioma cells.
    Neoplasia (New York, N.Y.), 2010, Volume: 12, Issue:1

    Topics: Amino Acids; Animals; Antineoplastic Agents, Alkylating; Apoptosis; Blotting, Western; Brain Neoplas

2010
Long-term temozolomide treatment induces marked amino metabolism modifications and an increase in TMZ sensitivity in Hs683 oligodendroglioma cells.
    Neoplasia (New York, N.Y.), 2010, Volume: 12, Issue:1

    Topics: Amino Acids; Animals; Antineoplastic Agents, Alkylating; Apoptosis; Blotting, Western; Brain Neoplas

2010
Long-term temozolomide treatment induces marked amino metabolism modifications and an increase in TMZ sensitivity in Hs683 oligodendroglioma cells.
    Neoplasia (New York, N.Y.), 2010, Volume: 12, Issue:1

    Topics: Amino Acids; Animals; Antineoplastic Agents, Alkylating; Apoptosis; Blotting, Western; Brain Neoplas

2010
Patient-tailored, imaging-guided, long-term temozolomide chemotherapy in patients with glioblastoma.
    Molecular imaging, 2010, Volume: 9, Issue:1

    Topics: Adult; Antineoplastic Agents, Alkylating; Brain Neoplasms; Carbon Radioisotopes; Dacarbazine; Dideox

2010
Patient-tailored, imaging-guided, long-term temozolomide chemotherapy in patients with glioblastoma.
    Molecular imaging, 2010, Volume: 9, Issue:1

    Topics: Adult; Antineoplastic Agents, Alkylating; Brain Neoplasms; Carbon Radioisotopes; Dacarbazine; Dideox

2010
Patient-tailored, imaging-guided, long-term temozolomide chemotherapy in patients with glioblastoma.
    Molecular imaging, 2010, Volume: 9, Issue:1

    Topics: Adult; Antineoplastic Agents, Alkylating; Brain Neoplasms; Carbon Radioisotopes; Dacarbazine; Dideox

2010
O6-Methylguanine DNA methyltransferase protein expression in tumor cells predicts outcome of temozolomide therapy in glioblastoma patients.
    Neuro-oncology, 2010, Volume: 12, Issue:1

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Biomarkers, Tumor; Blotting, West

2010
O6-Methylguanine DNA methyltransferase protein expression in tumor cells predicts outcome of temozolomide therapy in glioblastoma patients.
    Neuro-oncology, 2010, Volume: 12, Issue:1

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Biomarkers, Tumor; Blotting, West

2010
O6-Methylguanine DNA methyltransferase protein expression in tumor cells predicts outcome of temozolomide therapy in glioblastoma patients.
    Neuro-oncology, 2010, Volume: 12, Issue:1

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Biomarkers, Tumor; Blotting, West

2010
Noninvasive detection of temozolomide in brain tumor xenografts by magnetic resonance spectroscopy.
    Neuro-oncology, 2010, Volume: 12, Issue:1

    Topics: Animals; Antineoplastic Agents; Blood-Brain Barrier; Brain Neoplasms; Carbon Radioisotopes; Cell Lin

2010
Noninvasive detection of temozolomide in brain tumor xenografts by magnetic resonance spectroscopy.
    Neuro-oncology, 2010, Volume: 12, Issue:1

    Topics: Animals; Antineoplastic Agents; Blood-Brain Barrier; Brain Neoplasms; Carbon Radioisotopes; Cell Lin

2010
Noninvasive detection of temozolomide in brain tumor xenografts by magnetic resonance spectroscopy.
    Neuro-oncology, 2010, Volume: 12, Issue:1

    Topics: Animals; Antineoplastic Agents; Blood-Brain Barrier; Brain Neoplasms; Carbon Radioisotopes; Cell Lin

2010
Commentary on Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial (Lancet Oncol. 2009;10:459-466).
    Cancer, 2010, Apr-15, Volume: 116, Issue:8

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant; Clinical Trials, Phase I

2010
Commentary on Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial (Lancet Oncol. 2009;10:459-466).
    Cancer, 2010, Apr-15, Volume: 116, Issue:8

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant; Clinical Trials, Phase I

2010
Commentary on Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial (Lancet Oncol. 2009;10:459-466).
    Cancer, 2010, Apr-15, Volume: 116, Issue:8

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant; Clinical Trials, Phase I

2010
Promoter methylation analysis of O6-methylguanine-DNA methyltransferase in glioblastoma: detection by locked nucleic acid based quantitative PCR using an imprinted gene (SNURF) as a reference.
    BMC cancer, 2010, Feb-18, Volume: 10

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Carmustine; Dacarbazine; DNA Methyl

2010
Promoter methylation analysis of O6-methylguanine-DNA methyltransferase in glioblastoma: detection by locked nucleic acid based quantitative PCR using an imprinted gene (SNURF) as a reference.
    BMC cancer, 2010, Feb-18, Volume: 10

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Carmustine; Dacarbazine; DNA Methyl

2010
Promoter methylation analysis of O6-methylguanine-DNA methyltransferase in glioblastoma: detection by locked nucleic acid based quantitative PCR using an imprinted gene (SNURF) as a reference.
    BMC cancer, 2010, Feb-18, Volume: 10

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Carmustine; Dacarbazine; DNA Methyl

2010
Temozolomide and MGMT forever?
    Neuro-oncology, 2010, Volume: 12, Issue:3

    Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Clinical Trials as Topic; Dacarbazine; DNA Modifica

2010
Temozolomide and MGMT forever?
    Neuro-oncology, 2010, Volume: 12, Issue:3

    Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Clinical Trials as Topic; Dacarbazine; DNA Modifica

2010
Temozolomide and MGMT forever?
    Neuro-oncology, 2010, Volume: 12, Issue:3

    Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Clinical Trials as Topic; Dacarbazine; DNA Modifica

2010
Pseudoprogression following chemoradiotherapy for glioblastoma multiforme.
    The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques, 2010, Volume: 37, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2010
Pseudoprogression following chemoradiotherapy for glioblastoma multiforme.
    The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques, 2010, Volume: 37, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2010
Pseudoprogression following chemoradiotherapy for glioblastoma multiforme.
    The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques, 2010, Volume: 37, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease

2010
Combination of intracranial temozolomide with intracranial carmustine improves survival when compared with either treatment alone in a rodent glioma model.
    Neurosurgery, 2010, Volume: 66, Issue:3

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Carmustine; Dacarbazine; Disease Models

2010
Combination of intracranial temozolomide with intracranial carmustine improves survival when compared with either treatment alone in a rodent glioma model.
    Neurosurgery, 2010, Volume: 66, Issue:3

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Carmustine; Dacarbazine; Disease Models

2010
Combination of intracranial temozolomide with intracranial carmustine improves survival when compared with either treatment alone in a rodent glioma model.
    Neurosurgery, 2010, Volume: 66, Issue:3

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Carmustine; Dacarbazine; Disease Models

2010
MGMT modulates glioblastoma angiogenesis and response to the tyrosine kinase inhibitor sunitinib.
    Neuro-oncology, 2010, Volume: 12, Issue:8

    Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Combined Chemotherapy Protocols; Blotting, Western;

2010
MGMT modulates glioblastoma angiogenesis and response to the tyrosine kinase inhibitor sunitinib.
    Neuro-oncology, 2010, Volume: 12, Issue:8

    Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Combined Chemotherapy Protocols; Blotting, Western;

2010
MGMT modulates glioblastoma angiogenesis and response to the tyrosine kinase inhibitor sunitinib.
    Neuro-oncology, 2010, Volume: 12, Issue:8

    Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Combined Chemotherapy Protocols; Blotting, Western;

2010
Patent watch.
    Nature reviews. Drug discovery, 2010, Volume: 9, Issue:3

    Topics: Antineoplastic Agents, Alkylating; Antiparkinson Agents; Benzothiazoles; Brain Neoplasms; Dacarbazin

2010
Patent watch.
    Nature reviews. Drug discovery, 2010, Volume: 9, Issue:3

    Topics: Antineoplastic Agents, Alkylating; Antiparkinson Agents; Benzothiazoles; Brain Neoplasms; Dacarbazin

2010
Patent watch.
    Nature reviews. Drug discovery, 2010, Volume: 9, Issue:3

    Topics: Antineoplastic Agents, Alkylating; Antiparkinson Agents; Benzothiazoles; Brain Neoplasms; Dacarbazin

2010
Patterns and timing of recurrence after temozolomide-based chemoradiation for glioblastoma.
    International journal of radiation oncology, biology, physics, 2010, Nov-15, Volume: 78, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modalit

2010
Patterns and timing of recurrence after temozolomide-based chemoradiation for glioblastoma.
    International journal of radiation oncology, biology, physics, 2010, Nov-15, Volume: 78, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modalit

2010
Patterns and timing of recurrence after temozolomide-based chemoradiation for glioblastoma.
    International journal of radiation oncology, biology, physics, 2010, Nov-15, Volume: 78, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modalit

2010
Can hsp90alpha-targeted siRNA combined with TMZ be a future therapy for glioma?
    Cancer investigation, 2010, Volume: 28, Issue:6

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Cell Survival; Chemotherapy, A

2010
Can hsp90alpha-targeted siRNA combined with TMZ be a future therapy for glioma?
    Cancer investigation, 2010, Volume: 28, Issue:6

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Cell Survival; Chemotherapy, A

2010
Can hsp90alpha-targeted siRNA combined with TMZ be a future therapy for glioma?
    Cancer investigation, 2010, Volume: 28, Issue:6

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Cell Survival; Chemotherapy, A

2010
A small interference RNA screen revealed proteasome inhibition as strategy for glioblastoma therapy.
    Clinical neurosurgery, 2009, Volume: 56

    Topics: Animals; Antineoplastic Agents, Alkylating; Boronic Acids; Bortezomib; Brain Neoplasms; Cell Culture

2009
A small interference RNA screen revealed proteasome inhibition as strategy for glioblastoma therapy.
    Clinical neurosurgery, 2009, Volume: 56

    Topics: Animals; Antineoplastic Agents, Alkylating; Boronic Acids; Bortezomib; Brain Neoplasms; Cell Culture

2009
A small interference RNA screen revealed proteasome inhibition as strategy for glioblastoma therapy.
    Clinical neurosurgery, 2009, Volume: 56

    Topics: Animals; Antineoplastic Agents, Alkylating; Boronic Acids; Bortezomib; Brain Neoplasms; Cell Culture

2009
Far-distant metastases along the CSF pathway of glioblastoma multiforme during continuous low-dose chemotherapy with temozolomide and celecoxib.
    Neurosurgical review, 2010, Volume: 33, Issue:3

    Topics: Adult; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Brain Neoplasms; Celecoxib; Central

2010
Far-distant metastases along the CSF pathway of glioblastoma multiforme during continuous low-dose chemotherapy with temozolomide and celecoxib.
    Neurosurgical review, 2010, Volume: 33, Issue:3

    Topics: Adult; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Brain Neoplasms; Celecoxib; Central

2010
Far-distant metastases along the CSF pathway of glioblastoma multiforme during continuous low-dose chemotherapy with temozolomide and celecoxib.
    Neurosurgical review, 2010, Volume: 33, Issue:3

    Topics: Adult; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Brain Neoplasms; Celecoxib; Central

2010
Morphologic and molecular characterization of ATRT xenografts adapted for orthotopic therapeutic testing.
    Neuro-oncology, 2010, Volume: 12, Issue:4

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Female; Glioblastoma; Huma

2010
Morphologic and molecular characterization of ATRT xenografts adapted for orthotopic therapeutic testing.
    Neuro-oncology, 2010, Volume: 12, Issue:4

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Female; Glioblastoma; Huma

2010
Morphologic and molecular characterization of ATRT xenografts adapted for orthotopic therapeutic testing.
    Neuro-oncology, 2010, Volume: 12, Issue:4

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Female; Glioblastoma; Huma

2010
Therapy for recurrent high-grade gliomas: does continuous dose-intense temozolomide have a role?
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2010, Apr-20, Volume: 28, Issue:12

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant; Dacarbazine; Disease Pro

2010
Therapy for recurrent high-grade gliomas: does continuous dose-intense temozolomide have a role?
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2010, Apr-20, Volume: 28, Issue:12

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant; Dacarbazine; Disease Pro

2010
Therapy for recurrent high-grade gliomas: does continuous dose-intense temozolomide have a role?
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2010, Apr-20, Volume: 28, Issue:12

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant; Dacarbazine; Disease Pro

2010
Bevacizumab is active as a single agent against recurrent malignant gliomas.
    Anticancer research, 2010, Volume: 30, Issue:2

    Topics: Adult; Aged; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chem

2010
Bevacizumab is active as a single agent against recurrent malignant gliomas.
    Anticancer research, 2010, Volume: 30, Issue:2

    Topics: Adult; Aged; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chem

2010
Bevacizumab is active as a single agent against recurrent malignant gliomas.
    Anticancer research, 2010, Volume: 30, Issue:2

    Topics: Adult; Aged; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chem

2010
MicroRNA-181 family predicts response to concomitant chemoradiotherapy with temozolomide in glioblastoma patients.
    Neoplasma, 2010, Volume: 57, Issue:3

    Topics: Adult; Aged; Biomarkers, Tumor; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; DNA Methyla

2010
MicroRNA-181 family predicts response to concomitant chemoradiotherapy with temozolomide in glioblastoma patients.
    Neoplasma, 2010, Volume: 57, Issue:3

    Topics: Adult; Aged; Biomarkers, Tumor; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; DNA Methyla

2010
MicroRNA-181 family predicts response to concomitant chemoradiotherapy with temozolomide in glioblastoma patients.
    Neoplasma, 2010, Volume: 57, Issue:3

    Topics: Adult; Aged; Biomarkers, Tumor; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; DNA Methyla

2010
Survival of patients with newly diagnosed glioblastoma treated with radiation and temozolomide in research studies in the United States.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2010, Apr-15, Volume: 16, Issue:8

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Benzodiazepines; Biomedical Research; Brain Neoplasm

2010
Survival of patients with newly diagnosed glioblastoma treated with radiation and temozolomide in research studies in the United States.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2010, Apr-15, Volume: 16, Issue:8

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Benzodiazepines; Biomedical Research; Brain Neoplasm

2010
Survival of patients with newly diagnosed glioblastoma treated with radiation and temozolomide in research studies in the United States.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2010, Apr-15, Volume: 16, Issue:8

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Benzodiazepines; Biomedical Research; Brain Neoplasm

2010
Changes of the O6-methylguanine-DNA methyltransferase promoter methylation and MGMT protein expression after adjuvant treatment in glioblastoma.
    Oncology reports, 2010, Volume: 23, Issue:5

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Biopsy; Brain Neoplasms; Cell Line, Tum

2010
Changes of the O6-methylguanine-DNA methyltransferase promoter methylation and MGMT protein expression after adjuvant treatment in glioblastoma.
    Oncology reports, 2010, Volume: 23, Issue:5

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Biopsy; Brain Neoplasms; Cell Line, Tum

2010
Changes of the O6-methylguanine-DNA methyltransferase promoter methylation and MGMT protein expression after adjuvant treatment in glioblastoma.
    Oncology reports, 2010, Volume: 23, Issue:5

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Biopsy; Brain Neoplasms; Cell Line, Tum

2010
Inhibition of metalloproteinases derived from tumours: new insights in the treatment of human glioblastoma.
    Neuroscience, 2010, Jun-30, Volume: 168, Issue:2

    Topics: Antineoplastic Agents; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Cell Survival; Chemota

2010
Inhibition of metalloproteinases derived from tumours: new insights in the treatment of human glioblastoma.
    Neuroscience, 2010, Jun-30, Volume: 168, Issue:2

    Topics: Antineoplastic Agents; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Cell Survival; Chemota

2010
Inhibition of metalloproteinases derived from tumours: new insights in the treatment of human glioblastoma.
    Neuroscience, 2010, Jun-30, Volume: 168, Issue:2

    Topics: Antineoplastic Agents; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Cell Survival; Chemota

2010
Sensitivity to temozolomide in brain tumor initiating cells.
    Neuro-oncology, 2010, Volume: 12, Issue:7

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Survival; Dacarbazine; Glioblastoma; Humans

2010
Sensitivity to temozolomide in brain tumor initiating cells.
    Neuro-oncology, 2010, Volume: 12, Issue:7

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Survival; Dacarbazine; Glioblastoma; Humans

2010
Sensitivity to temozolomide in brain tumor initiating cells.
    Neuro-oncology, 2010, Volume: 12, Issue:7

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Survival; Dacarbazine; Glioblastoma; Humans

2010
The chemokine receptor CXCR7 is highly expressed in human glioma cells and mediates antiapoptotic effects.
    Cancer research, 2010, Apr-15, Volume: 70, Issue:8

    Topics: Apoptosis; Apoptosis Regulatory Proteins; Brain Neoplasms; Camptothecin; Cell Movement; Cell Prolife

2010
The chemokine receptor CXCR7 is highly expressed in human glioma cells and mediates antiapoptotic effects.
    Cancer research, 2010, Apr-15, Volume: 70, Issue:8

    Topics: Apoptosis; Apoptosis Regulatory Proteins; Brain Neoplasms; Camptothecin; Cell Movement; Cell Prolife

2010
The chemokine receptor CXCR7 is highly expressed in human glioma cells and mediates antiapoptotic effects.
    Cancer research, 2010, Apr-15, Volume: 70, Issue:8

    Topics: Apoptosis; Apoptosis Regulatory Proteins; Brain Neoplasms; Camptothecin; Cell Movement; Cell Prolife

2010
Temozolomide/PLGA microparticles: a new protocol for treatment of glioma in rats.
    Medical oncology (Northwood, London, England), 2011, Volume: 28, Issue:3

    Topics: Animals; Antineoplastic Agents; Apoptosis; Brain Neoplasms; Dacarbazine; Glioma; In Situ Nick-End La

2011
Temozolomide/PLGA microparticles: a new protocol for treatment of glioma in rats.
    Medical oncology (Northwood, London, England), 2011, Volume: 28, Issue:3

    Topics: Animals; Antineoplastic Agents; Apoptosis; Brain Neoplasms; Dacarbazine; Glioma; In Situ Nick-End La

2011
Temozolomide/PLGA microparticles: a new protocol for treatment of glioma in rats.
    Medical oncology (Northwood, London, England), 2011, Volume: 28, Issue:3

    Topics: Animals; Antineoplastic Agents; Apoptosis; Brain Neoplasms; Dacarbazine; Glioma; In Situ Nick-End La

2011
Pattern of failure after limited margin radiotherapy and temozolomide for glioblastoma.
    International journal of radiation oncology, biology, physics, 2011, Jan-01, Volume: 79, Issue:1

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Arsenic Trioxide; Arsenicals; Brain Neoplasms; Combi

2011
Pattern of failure after limited margin radiotherapy and temozolomide for glioblastoma.
    International journal of radiation oncology, biology, physics, 2011, Jan-01, Volume: 79, Issue:1

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Arsenic Trioxide; Arsenicals; Brain Neoplasms; Combi

2011
Pattern of failure after limited margin radiotherapy and temozolomide for glioblastoma.
    International journal of radiation oncology, biology, physics, 2011, Jan-01, Volume: 79, Issue:1

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Arsenic Trioxide; Arsenicals; Brain Neoplasms; Combi

2011
Gene expression profiling predicts response to temozolomide in malignant gliomas.
    International journal of oncology, 2010, Volume: 36, Issue:6

    Topics: Antineoplastic Agents, Alkylating; Blotting, Western; Brain Neoplasms; Cell Line, Tumor; Dacarbazine

2010
Gene expression profiling predicts response to temozolomide in malignant gliomas.
    International journal of oncology, 2010, Volume: 36, Issue:6

    Topics: Antineoplastic Agents, Alkylating; Blotting, Western; Brain Neoplasms; Cell Line, Tumor; Dacarbazine

2010
Gene expression profiling predicts response to temozolomide in malignant gliomas.
    International journal of oncology, 2010, Volume: 36, Issue:6

    Topics: Antineoplastic Agents, Alkylating; Blotting, Western; Brain Neoplasms; Cell Line, Tumor; Dacarbazine

2010
Prognostic value of MGMT promoter methylation in glioblastoma patients treated with temozolomide-based chemoradiation: a Portuguese multicentre study.
    Oncology reports, 2010, Volume: 23, Issue:6

    Topics: Antineoplastic Agents; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; DNA Methylation; Fem

2010
Prognostic value of MGMT promoter methylation in glioblastoma patients treated with temozolomide-based chemoradiation: a Portuguese multicentre study.
    Oncology reports, 2010, Volume: 23, Issue:6

    Topics: Antineoplastic Agents; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; DNA Methylation; Fem

2010
Prognostic value of MGMT promoter methylation in glioblastoma patients treated with temozolomide-based chemoradiation: a Portuguese multicentre study.
    Oncology reports, 2010, Volume: 23, Issue:6

    Topics: Antineoplastic Agents; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; DNA Methylation; Fem

2010
Intracerebral hemorrhage secondary to thrombocytopenia in a patient treated with temozolomide.
    Clinical neurology and neurosurgery, 2010, Volume: 112, Issue:8

    Topics: Adult; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cerebral Hemorrhage; Dacarbazine; Dose-Re

2010
Intracerebral hemorrhage secondary to thrombocytopenia in a patient treated with temozolomide.
    Clinical neurology and neurosurgery, 2010, Volume: 112, Issue:8

    Topics: Adult; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cerebral Hemorrhage; Dacarbazine; Dose-Re

2010
Intracerebral hemorrhage secondary to thrombocytopenia in a patient treated with temozolomide.
    Clinical neurology and neurosurgery, 2010, Volume: 112, Issue:8

    Topics: Adult; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cerebral Hemorrhage; Dacarbazine; Dose-Re

2010
Effectiveness of temozolomide treatment used at the same time with radiotherapy and adjuvant temozolomide; concomitant therapy of glioblastoma multiforme: multivariate analysis and other prognostic factors.
    Journal of neurosurgical sciences, 2010, Volume: 54, Issue:1

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant;

2010
Effectiveness of temozolomide treatment used at the same time with radiotherapy and adjuvant temozolomide; concomitant therapy of glioblastoma multiforme: multivariate analysis and other prognostic factors.
    Journal of neurosurgical sciences, 2010, Volume: 54, Issue:1

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant;

2010
Effectiveness of temozolomide treatment used at the same time with radiotherapy and adjuvant temozolomide; concomitant therapy of glioblastoma multiforme: multivariate analysis and other prognostic factors.
    Journal of neurosurgical sciences, 2010, Volume: 54, Issue:1

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant;

2010
Expression of CD74 in high grade gliomas: a potential role in temozolomide resistance.
    Journal of neuro-oncology, 2010, Volume: 100, Issue:2

    Topics: Animals; Antigens, Differentiation, B-Lymphocyte; Antineoplastic Agents; Blotting, Western; Brain Ne

2010
Expression of CD74 in high grade gliomas: a potential role in temozolomide resistance.
    Journal of neuro-oncology, 2010, Volume: 100, Issue:2

    Topics: Animals; Antigens, Differentiation, B-Lymphocyte; Antineoplastic Agents; Blotting, Western; Brain Ne

2010
Expression of CD74 in high grade gliomas: a potential role in temozolomide resistance.
    Journal of neuro-oncology, 2010, Volume: 100, Issue:2

    Topics: Animals; Antigens, Differentiation, B-Lymphocyte; Antineoplastic Agents; Blotting, Western; Brain Ne

2010
Biodegradable carmustine wafers (Gliadel) alone or in combination with chemoradiotherapy: the French experience.
    Annals of surgical oncology, 2010, Volume: 17, Issue:7

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Biocompa

2010
Biodegradable carmustine wafers (Gliadel) alone or in combination with chemoradiotherapy: the French experience.
    Annals of surgical oncology, 2010, Volume: 17, Issue:7

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Biocompa

2010
Biodegradable carmustine wafers (Gliadel) alone or in combination with chemoradiotherapy: the French experience.
    Annals of surgical oncology, 2010, Volume: 17, Issue:7

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Biocompa

2010
Continuous low-dose temozolomide and celecoxib in recurrent glioblastoma.
    Journal of neuro-oncology, 2010, Volume: 100, Issue:3

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Brai

2010
Continuous low-dose temozolomide and celecoxib in recurrent glioblastoma.
    Journal of neuro-oncology, 2010, Volume: 100, Issue:3

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Brai

2010
Continuous low-dose temozolomide and celecoxib in recurrent glioblastoma.
    Journal of neuro-oncology, 2010, Volume: 100, Issue:3

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Brai

2010
Minimally cytotoxic doses of temozolomide produce radiosensitization in human glioblastoma cells regardless of MGMT expression.
    Molecular cancer therapeutics, 2010, Volume: 9, Issue:5

    Topics: Adult; Antineoplastic Agents; Brain Neoplasms; Dacarbazine; DNA Mismatch Repair; DNA Modification Me

2010
Minimally cytotoxic doses of temozolomide produce radiosensitization in human glioblastoma cells regardless of MGMT expression.
    Molecular cancer therapeutics, 2010, Volume: 9, Issue:5

    Topics: Adult; Antineoplastic Agents; Brain Neoplasms; Dacarbazine; DNA Mismatch Repair; DNA Modification Me

2010
Minimally cytotoxic doses of temozolomide produce radiosensitization in human glioblastoma cells regardless of MGMT expression.
    Molecular cancer therapeutics, 2010, Volume: 9, Issue:5

    Topics: Adult; Antineoplastic Agents; Brain Neoplasms; Dacarbazine; DNA Mismatch Repair; DNA Modification Me

2010
Nitrosourea-based chemotherapy for low grade gliomas failing initial treatment with temozolomide.
    Journal of neuro-oncology, 2010, Volume: 100, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Dis

2010
Nitrosourea-based chemotherapy for low grade gliomas failing initial treatment with temozolomide.
    Journal of neuro-oncology, 2010, Volume: 100, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Dis

2010
Nitrosourea-based chemotherapy for low grade gliomas failing initial treatment with temozolomide.
    Journal of neuro-oncology, 2010, Volume: 100, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Dis

2010
Evaluation of diffusion parameters as early biomarkers of disease progression in glioblastoma multiforme.
    Neuro-oncology, 2010, Volume: 12, Issue:9

    Topics: Antineoplastic Agents; Biomarkers, Tumor; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; D

2010
Evaluation of diffusion parameters as early biomarkers of disease progression in glioblastoma multiforme.
    Neuro-oncology, 2010, Volume: 12, Issue:9

    Topics: Antineoplastic Agents; Biomarkers, Tumor; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; D

2010
Evaluation of diffusion parameters as early biomarkers of disease progression in glioblastoma multiforme.
    Neuro-oncology, 2010, Volume: 12, Issue:9

    Topics: Antineoplastic Agents; Biomarkers, Tumor; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; D

2010
Preoperative chemotherapy for infiltrative low-grade oligoastrocytoma: a useful strategy to maximize surgical resection -case report-.
    Neurologia medico-chirurgica, 2010, Volume: 50, Issue:5

    Topics: Adult; Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neoplasms; Chemotherapy, Adjuvant; Corp

2010
Preoperative chemotherapy for infiltrative low-grade oligoastrocytoma: a useful strategy to maximize surgical resection -case report-.
    Neurologia medico-chirurgica, 2010, Volume: 50, Issue:5

    Topics: Adult; Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neoplasms; Chemotherapy, Adjuvant; Corp

2010
Preoperative chemotherapy for infiltrative low-grade oligoastrocytoma: a useful strategy to maximize surgical resection -case report-.
    Neurologia medico-chirurgica, 2010, Volume: 50, Issue:5

    Topics: Adult; Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neoplasms; Chemotherapy, Adjuvant; Corp

2010
Efficient delivery of liposome-mediated MGMT-siRNA reinforces the cytotoxity of temozolomide in GBM-initiating cells.
    Gene therapy, 2010, Volume: 17, Issue:11

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Combined Modality The

2010
Efficient delivery of liposome-mediated MGMT-siRNA reinforces the cytotoxity of temozolomide in GBM-initiating cells.
    Gene therapy, 2010, Volume: 17, Issue:11

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Combined Modality The

2010
Efficient delivery of liposome-mediated MGMT-siRNA reinforces the cytotoxity of temozolomide in GBM-initiating cells.
    Gene therapy, 2010, Volume: 17, Issue:11

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Combined Modality The

2010
Initial experience involving treatment and retreatment with carmustine wafers in combination with oral temozolomide: long-term survival in a child with relapsed glioblastoma multiforme.
    Journal of pediatric hematology/oncology, 2010, Volume: 32, Issue:5

    Topics: Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carmustine; Child; Combined Modalit

2010
Initial experience involving treatment and retreatment with carmustine wafers in combination with oral temozolomide: long-term survival in a child with relapsed glioblastoma multiforme.
    Journal of pediatric hematology/oncology, 2010, Volume: 32, Issue:5

    Topics: Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carmustine; Child; Combined Modalit

2010
Initial experience involving treatment and retreatment with carmustine wafers in combination with oral temozolomide: long-term survival in a child with relapsed glioblastoma multiforme.
    Journal of pediatric hematology/oncology, 2010, Volume: 32, Issue:5

    Topics: Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carmustine; Child; Combined Modalit

2010
Embryonic stem cell (ESC)-mediated transgene delivery induces growth suppression, apoptosis and radiosensitization, and overcomes temozolomide resistance in malignant gliomas.
    Cancer gene therapy, 2010, Volume: 17, Issue:9

    Topics: Animals; Antineoplastic Agents, Alkylating; Apoptosis; Blotting, Western; Brain Neoplasms; Cell Prol

2010
Embryonic stem cell (ESC)-mediated transgene delivery induces growth suppression, apoptosis and radiosensitization, and overcomes temozolomide resistance in malignant gliomas.
    Cancer gene therapy, 2010, Volume: 17, Issue:9

    Topics: Animals; Antineoplastic Agents, Alkylating; Apoptosis; Blotting, Western; Brain Neoplasms; Cell Prol

2010
Embryonic stem cell (ESC)-mediated transgene delivery induces growth suppression, apoptosis and radiosensitization, and overcomes temozolomide resistance in malignant gliomas.
    Cancer gene therapy, 2010, Volume: 17, Issue:9

    Topics: Animals; Antineoplastic Agents, Alkylating; Apoptosis; Blotting, Western; Brain Neoplasms; Cell Prol

2010
Changes in relative cerebral blood volume 1 month after radiation-temozolomide therapy can help predict overall survival in patients with glioblastoma.
    Radiology, 2010, Volume: 256, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Blood Volume; Brain Neoplasms; Da

2010
Changes in relative cerebral blood volume 1 month after radiation-temozolomide therapy can help predict overall survival in patients with glioblastoma.
    Radiology, 2010, Volume: 256, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Blood Volume; Brain Neoplasms; Da

2010
Changes in relative cerebral blood volume 1 month after radiation-temozolomide therapy can help predict overall survival in patients with glioblastoma.
    Radiology, 2010, Volume: 256, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Blood Volume; Brain Neoplasms; Da

2010
PTEN loss compromises homologous recombination repair in astrocytes: implications for glioblastoma therapy with temozolomide or poly(ADP-ribose) polymerase inhibitors.
    Cancer research, 2010, Jul-01, Volume: 70, Issue:13

    Topics: Animals; Antineoplastic Agents, Alkylating; Astrocytes; Benzimidazoles; Brain Neoplasms; Cyclin-Depe

2010
PTEN loss compromises homologous recombination repair in astrocytes: implications for glioblastoma therapy with temozolomide or poly(ADP-ribose) polymerase inhibitors.
    Cancer research, 2010, Jul-01, Volume: 70, Issue:13

    Topics: Animals; Antineoplastic Agents, Alkylating; Astrocytes; Benzimidazoles; Brain Neoplasms; Cyclin-Depe

2010
PTEN loss compromises homologous recombination repair in astrocytes: implications for glioblastoma therapy with temozolomide or poly(ADP-ribose) polymerase inhibitors.
    Cancer research, 2010, Jul-01, Volume: 70, Issue:13

    Topics: Animals; Antineoplastic Agents, Alkylating; Astrocytes; Benzimidazoles; Brain Neoplasms; Cyclin-Depe

2010
Temozolomide (Temodar).
    AJNR. American journal of neuroradiology, 2010, Volume: 31, Issue:8

    Topics: Administration, Oral; Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neoplasms; Dacarbazine;

2010
Temozolomide (Temodar).
    AJNR. American journal of neuroradiology, 2010, Volume: 31, Issue:8

    Topics: Administration, Oral; Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neoplasms; Dacarbazine;

2010
Temozolomide (Temodar).
    AJNR. American journal of neuroradiology, 2010, Volume: 31, Issue:8

    Topics: Administration, Oral; Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neoplasms; Dacarbazine;

2010
High-grade malignant glioma: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2010, Volume: 21 Suppl 5

    Topics: Adrenal Cortex Hormones; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Europe; Fo

2010
High-grade malignant glioma: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2010, Volume: 21 Suppl 5

    Topics: Adrenal Cortex Hormones; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Europe; Fo

2010
High-grade malignant glioma: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2010, Volume: 21 Suppl 5

    Topics: Adrenal Cortex Hormones; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Europe; Fo

2010
High-grade malignant glioma: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2010, Volume: 21 Suppl 5

    Topics: Adrenal Cortex Hormones; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Europe; Fo

2010
High-grade malignant glioma: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2010, Volume: 21 Suppl 5

    Topics: Adrenal Cortex Hormones; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Europe; Fo

2010
High-grade malignant glioma: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2010, Volume: 21 Suppl 5

    Topics: Adrenal Cortex Hormones; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Europe; Fo

2010
High-grade malignant glioma: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2010, Volume: 21 Suppl 5

    Topics: Adrenal Cortex Hormones; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Europe; Fo

2010
High-grade malignant glioma: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2010, Volume: 21 Suppl 5

    Topics: Adrenal Cortex Hormones; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Europe; Fo

2010
High-grade malignant glioma: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2010, Volume: 21 Suppl 5

    Topics: Adrenal Cortex Hormones; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Europe; Fo

2010
High-grade malignant glioma: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2010, Volume: 21 Suppl 5

    Topics: Adrenal Cortex Hormones; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Europe; Fo

2010
High-grade malignant glioma: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2010, Volume: 21 Suppl 5

    Topics: Adrenal Cortex Hormones; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Europe; Fo

2010
High-grade malignant glioma: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2010, Volume: 21 Suppl 5

    Topics: Adrenal Cortex Hormones; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Europe; Fo

2010
Up-front temozolomide in elderly patients with anaplastic oligodendroglioma and oligoastrocytoma.
    Journal of neuro-oncology, 2011, Volume: 101, Issue:3

    Topics: Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; DNA Methyl

2011
Up-front temozolomide in elderly patients with anaplastic oligodendroglioma and oligoastrocytoma.
    Journal of neuro-oncology, 2011, Volume: 101, Issue:3

    Topics: Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; DNA Methyl

2011
Up-front temozolomide in elderly patients with anaplastic oligodendroglioma and oligoastrocytoma.
    Journal of neuro-oncology, 2011, Volume: 101, Issue:3

    Topics: Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; DNA Methyl

2011
MGMT gene promoter methylation in pediatric glioblastomas.
    Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 2010, Volume: 26, Issue:11

    Topics: Adolescent; Antineoplastic Agents, Alkylating; Brain Neoplasms; Child; Child, Preschool; Dacarbazine

2010
MGMT gene promoter methylation in pediatric glioblastomas.
    Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 2010, Volume: 26, Issue:11

    Topics: Adolescent; Antineoplastic Agents, Alkylating; Brain Neoplasms; Child; Child, Preschool; Dacarbazine

2010
MGMT gene promoter methylation in pediatric glioblastomas.
    Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 2010, Volume: 26, Issue:11

    Topics: Adolescent; Antineoplastic Agents, Alkylating; Brain Neoplasms; Child; Child, Preschool; Dacarbazine

2010
Effect of aberrant p53 function on temozolomide sensitivity of glioma cell lines and brain tumor initiating cells from glioblastoma.
    Journal of neuro-oncology, 2011, Volume: 102, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Blotting, Western; Brain Neoplasms; Dacarbazine; DNA Methylation;

2011
Effect of aberrant p53 function on temozolomide sensitivity of glioma cell lines and brain tumor initiating cells from glioblastoma.
    Journal of neuro-oncology, 2011, Volume: 102, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Blotting, Western; Brain Neoplasms; Dacarbazine; DNA Methylation;

2011
Effect of aberrant p53 function on temozolomide sensitivity of glioma cell lines and brain tumor initiating cells from glioblastoma.
    Journal of neuro-oncology, 2011, Volume: 102, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Blotting, Western; Brain Neoplasms; Dacarbazine; DNA Methylation;

2011
Rash in four patients with brain tumor-related epilepsy in monotherapy with oxcarbazepine, during radiotherapy.
    Journal of neurology, 2010, Volume: 257, Issue:11

    Topics: Anticonvulsants; Antineoplastic Agents; Brain Neoplasms; Carbamazepine; Combined Modality Therapy; C

2010
Rash in four patients with brain tumor-related epilepsy in monotherapy with oxcarbazepine, during radiotherapy.
    Journal of neurology, 2010, Volume: 257, Issue:11

    Topics: Anticonvulsants; Antineoplastic Agents; Brain Neoplasms; Carbamazepine; Combined Modality Therapy; C

2010
Rash in four patients with brain tumor-related epilepsy in monotherapy with oxcarbazepine, during radiotherapy.
    Journal of neurology, 2010, Volume: 257, Issue:11

    Topics: Anticonvulsants; Antineoplastic Agents; Brain Neoplasms; Carbamazepine; Combined Modality Therapy; C

2010
Convection-enhanced delivery of a synthetic retinoid Am80, loaded into polymeric micelles, prolongs the survival of rats bearing intracranial glioblastoma xenografts.
    The Tohoku journal of experimental medicine, 2010, Volume: 221, Issue:4

    Topics: Animals; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Apoptosis; Benzoates; Brain Neopl

2010
Convection-enhanced delivery of a synthetic retinoid Am80, loaded into polymeric micelles, prolongs the survival of rats bearing intracranial glioblastoma xenografts.
    The Tohoku journal of experimental medicine, 2010, Volume: 221, Issue:4

    Topics: Animals; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Apoptosis; Benzoates; Brain Neopl

2010
Convection-enhanced delivery of a synthetic retinoid Am80, loaded into polymeric micelles, prolongs the survival of rats bearing intracranial glioblastoma xenografts.
    The Tohoku journal of experimental medicine, 2010, Volume: 221, Issue:4

    Topics: Animals; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Apoptosis; Benzoates; Brain Neopl

2010
Influence of iMRI-guidance on the extent of resection and survival of patients with glioblastoma multiforme.
    Technology in cancer research & treatment, 2010, Volume: 9, Issue:4

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Female; Glioblastoma; Humans; Magne

2010
Influence of iMRI-guidance on the extent of resection and survival of patients with glioblastoma multiforme.
    Technology in cancer research & treatment, 2010, Volume: 9, Issue:4

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Female; Glioblastoma; Humans; Magne

2010
Influence of iMRI-guidance on the extent of resection and survival of patients with glioblastoma multiforme.
    Technology in cancer research & treatment, 2010, Volume: 9, Issue:4

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Female; Glioblastoma; Humans; Magne

2010
Radiation induced early necrosis in patients with malignant gliomas receiving temozolomide.
    Clinical neurology and neurosurgery, 2010, Volume: 112, Issue:8

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbaz

2010
Radiation induced early necrosis in patients with malignant gliomas receiving temozolomide.
    Clinical neurology and neurosurgery, 2010, Volume: 112, Issue:8

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbaz

2010
Radiation induced early necrosis in patients with malignant gliomas receiving temozolomide.
    Clinical neurology and neurosurgery, 2010, Volume: 112, Issue:8

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbaz

2010
Effect of alternative temozolomide schedules on glioblastoma O(6)-methylguanine-DNA methyltransferase activity and survival.
    British journal of cancer, 2010, Aug-10, Volume: 103, Issue:4

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Dacarbazine; Dose-Res

2010
Effect of alternative temozolomide schedules on glioblastoma O(6)-methylguanine-DNA methyltransferase activity and survival.
    British journal of cancer, 2010, Aug-10, Volume: 103, Issue:4

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Dacarbazine; Dose-Res

2010
Effect of alternative temozolomide schedules on glioblastoma O(6)-methylguanine-DNA methyltransferase activity and survival.
    British journal of cancer, 2010, Aug-10, Volume: 103, Issue:4

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Dacarbazine; Dose-Res

2010
Pseudoprogression in patients with malignant gliomas treated with concurrent temozolomide and radiotherapy: potential role of p53.
    Journal of neuro-oncology, 2011, Volume: 102, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modalit

2011
Pseudoprogression in patients with malignant gliomas treated with concurrent temozolomide and radiotherapy: potential role of p53.
    Journal of neuro-oncology, 2011, Volume: 102, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modalit

2011
Pseudoprogression in patients with malignant gliomas treated with concurrent temozolomide and radiotherapy: potential role of p53.
    Journal of neuro-oncology, 2011, Volume: 102, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modalit

2011
MiR-21 protected human glioblastoma U87MG cells from chemotherapeutic drug temozolomide induced apoptosis by decreasing Bax/Bcl-2 ratio and caspase-3 activity.
    Brain research, 2010, Sep-17, Volume: 1352

    Topics: Antineoplastic Agents, Alkylating; Apoptosis; bcl-2-Associated X Protein; Brain Neoplasms; Caspase 3

2010
MiR-21 protected human glioblastoma U87MG cells from chemotherapeutic drug temozolomide induced apoptosis by decreasing Bax/Bcl-2 ratio and caspase-3 activity.
    Brain research, 2010, Sep-17, Volume: 1352

    Topics: Antineoplastic Agents, Alkylating; Apoptosis; bcl-2-Associated X Protein; Brain Neoplasms; Caspase 3

2010
MiR-21 protected human glioblastoma U87MG cells from chemotherapeutic drug temozolomide induced apoptosis by decreasing Bax/Bcl-2 ratio and caspase-3 activity.
    Brain research, 2010, Sep-17, Volume: 1352

    Topics: Antineoplastic Agents, Alkylating; Apoptosis; bcl-2-Associated X Protein; Brain Neoplasms; Caspase 3

2010
A pilot study of hypofractionated radiation therapy with temozolomide for adults with glioblastoma multiforme.
    Journal of neuro-oncology, 2011, Volume: 102, Issue:2

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbaz

2011
A pilot study of hypofractionated radiation therapy with temozolomide for adults with glioblastoma multiforme.
    Journal of neuro-oncology, 2011, Volume: 102, Issue:2

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbaz

2011
A pilot study of hypofractionated radiation therapy with temozolomide for adults with glioblastoma multiforme.
    Journal of neuro-oncology, 2011, Volume: 102, Issue:2

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbaz

2011
Patterns of care and survival in a retrospective analysis of 1059 patients with glioblastoma multiforme treated between 2002 and 2007: a multicenter study by the Central Nervous System Study Group of Airo (italian Association of Radiation Oncology).
    Neurosurgery, 2010, Volume: 67, Issue:2

    Topics: Adult; Age Factors; Aged; Aged, 80 and over; Analysis of Variance; Antineoplastic Agents; Antineopla

2010
Patterns of care and survival in a retrospective analysis of 1059 patients with glioblastoma multiforme treated between 2002 and 2007: a multicenter study by the Central Nervous System Study Group of Airo (italian Association of Radiation Oncology).
    Neurosurgery, 2010, Volume: 67, Issue:2

    Topics: Adult; Age Factors; Aged; Aged, 80 and over; Analysis of Variance; Antineoplastic Agents; Antineopla

2010
Patterns of care and survival in a retrospective analysis of 1059 patients with glioblastoma multiforme treated between 2002 and 2007: a multicenter study by the Central Nervous System Study Group of Airo (italian Association of Radiation Oncology).
    Neurosurgery, 2010, Volume: 67, Issue:2

    Topics: Adult; Age Factors; Aged; Aged, 80 and over; Analysis of Variance; Antineoplastic Agents; Antineopla

2010
Prognostic value of early [18F]fluoroethyltyrosine positron emission tomography after radiochemotherapy in glioblastoma multiforme.
    International journal of radiation oncology, biology, physics, 2011, May-01, Volume: 80, Issue:1

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbaz

2011
Prognostic value of early [18F]fluoroethyltyrosine positron emission tomography after radiochemotherapy in glioblastoma multiforme.
    International journal of radiation oncology, biology, physics, 2011, May-01, Volume: 80, Issue:1

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbaz

2011
Prognostic value of early [18F]fluoroethyltyrosine positron emission tomography after radiochemotherapy in glioblastoma multiforme.
    International journal of radiation oncology, biology, physics, 2011, May-01, Volume: 80, Issue:1

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbaz

2011
Combination of 6-thioguanine, capecitabine, and celecoxib with temozolomide or lomustine for recurrent high-grade glioma.
    Journal of neuro-oncology, 2011, Volume: 102, Issue:2

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Capecitabine; Celecoxi

2011
Combination of 6-thioguanine, capecitabine, and celecoxib with temozolomide or lomustine for recurrent high-grade glioma.
    Journal of neuro-oncology, 2011, Volume: 102, Issue:2

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Capecitabine; Celecoxi

2011
Combination of 6-thioguanine, capecitabine, and celecoxib with temozolomide or lomustine for recurrent high-grade glioma.
    Journal of neuro-oncology, 2011, Volume: 102, Issue:2

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Capecitabine; Celecoxi

2011
Temozolomide, quercetin and cell death in the MOGGCCM astrocytoma cell line.
    Chemico-biological interactions, 2010, Oct-06, Volume: 188, Issue:1

    Topics: Apoptosis; Astrocytoma; Blotting, Western; Brain Neoplasms; Cell Death; Cell Line, Tumor; Dacarbazin

2010
Temozolomide, quercetin and cell death in the MOGGCCM astrocytoma cell line.
    Chemico-biological interactions, 2010, Oct-06, Volume: 188, Issue:1

    Topics: Apoptosis; Astrocytoma; Blotting, Western; Brain Neoplasms; Cell Death; Cell Line, Tumor; Dacarbazin

2010
Temozolomide, quercetin and cell death in the MOGGCCM astrocytoma cell line.
    Chemico-biological interactions, 2010, Oct-06, Volume: 188, Issue:1

    Topics: Apoptosis; Astrocytoma; Blotting, Western; Brain Neoplasms; Cell Death; Cell Line, Tumor; Dacarbazin

2010
Acute lymphoblastic leukemia after temozolomide treatment for anaplastic astrocytoma in a child with a germline TP53 mutation.
    Pediatric blood & cancer, 2010, Volume: 55, Issue:3

    Topics: Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neoplasms; Child; Dacarbazine; Female; Frontal

2010
Acute lymphoblastic leukemia after temozolomide treatment for anaplastic astrocytoma in a child with a germline TP53 mutation.
    Pediatric blood & cancer, 2010, Volume: 55, Issue:3

    Topics: Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neoplasms; Child; Dacarbazine; Female; Frontal

2010
Acute lymphoblastic leukemia after temozolomide treatment for anaplastic astrocytoma in a child with a germline TP53 mutation.
    Pediatric blood & cancer, 2010, Volume: 55, Issue:3

    Topics: Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neoplasms; Child; Dacarbazine; Female; Frontal

2010
Long-term outcomes in children with glioblastoma.
    Journal of neurosurgery. Pediatrics, 2010, Volume: 6, Issue:2

    Topics: Adolescent; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant; Child; Child

2010
Long-term outcomes in children with glioblastoma.
    Journal of neurosurgery. Pediatrics, 2010, Volume: 6, Issue:2

    Topics: Adolescent; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant; Child; Child

2010
Long-term outcomes in children with glioblastoma.
    Journal of neurosurgery. Pediatrics, 2010, Volume: 6, Issue:2

    Topics: Adolescent; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant; Child; Child

2010
Kitten-transmitted Bordetella bronchiseptica infection in a patient receiving temozolomide for glioblastoma.
    Journal of neuro-oncology, 2011, Volume: 102, Issue:2

    Topics: Animals; Antineoplastic Agents, Alkylating; Bordetella bronchiseptica; Bordetella Infections; Brain

2011
Kitten-transmitted Bordetella bronchiseptica infection in a patient receiving temozolomide for glioblastoma.
    Journal of neuro-oncology, 2011, Volume: 102, Issue:2

    Topics: Animals; Antineoplastic Agents, Alkylating; Bordetella bronchiseptica; Bordetella Infections; Brain

2011
Kitten-transmitted Bordetella bronchiseptica infection in a patient receiving temozolomide for glioblastoma.
    Journal of neuro-oncology, 2011, Volume: 102, Issue:2

    Topics: Animals; Antineoplastic Agents, Alkylating; Bordetella bronchiseptica; Bordetella Infections; Brain

2011
[Side effects of temozolomide treatment in patient with glioblastoma multiforme--case study].
    Przeglad lekarski, 2010, Volume: 67, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant; Dacarbazine; Female; Gli

2010
[Side effects of temozolomide treatment in patient with glioblastoma multiforme--case study].
    Przeglad lekarski, 2010, Volume: 67, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant; Dacarbazine; Female; Gli

2010
[Side effects of temozolomide treatment in patient with glioblastoma multiforme--case study].
    Przeglad lekarski, 2010, Volume: 67, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant; Dacarbazine; Female; Gli

2010
Correlation between O6-methylguanine-DNA methyltransferase and survival in elderly patients with glioblastoma treated with radiotherapy plus concomitant and adjuvant temozolomide.
    Journal of neuro-oncology, 2011, Volume: 102, Issue:2

    Topics: Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Thera

2011
Correlation between O6-methylguanine-DNA methyltransferase and survival in elderly patients with glioblastoma treated with radiotherapy plus concomitant and adjuvant temozolomide.
    Journal of neuro-oncology, 2011, Volume: 102, Issue:2

    Topics: Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Thera

2011
Correlation between O6-methylguanine-DNA methyltransferase and survival in elderly patients with glioblastoma treated with radiotherapy plus concomitant and adjuvant temozolomide.
    Journal of neuro-oncology, 2011, Volume: 102, Issue:2

    Topics: Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Thera

2011
First-line treatment of malignant glioma with carmustine implants followed by concomitant radiochemotherapy: a multicenter experience.
    Neurosurgical review, 2010, Volume: 33, Issue:4

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Carmustine; Combined Modality Thera

2010
First-line treatment of malignant glioma with carmustine implants followed by concomitant radiochemotherapy: a multicenter experience.
    Neurosurgical review, 2010, Volume: 33, Issue:4

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Carmustine; Combined Modality Thera

2010
First-line treatment of malignant glioma with carmustine implants followed by concomitant radiochemotherapy: a multicenter experience.
    Neurosurgical review, 2010, Volume: 33, Issue:4

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Carmustine; Combined Modality Thera

2010
Hepatic encephalopathy after treatment with temozolomide.
    Journal of neuro-oncology, 2011, Volume: 103, Issue:1

    Topics: Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Fe

2011
Hepatic encephalopathy after treatment with temozolomide.
    Journal of neuro-oncology, 2011, Volume: 103, Issue:1

    Topics: Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Fe

2011
Hepatic encephalopathy after treatment with temozolomide.
    Journal of neuro-oncology, 2011, Volume: 103, Issue:1

    Topics: Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Fe

2011
Favorable prognosis in patients with high-grade glioma with radiation necrosis: the University of Colorado reoperation series.
    International journal of radiation oncology, biology, physics, 2011, Sep-01, Volume: 81, Issue:1

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neoplasms; Carmustine; Colorado;

2011
Favorable prognosis in patients with high-grade glioma with radiation necrosis: the University of Colorado reoperation series.
    International journal of radiation oncology, biology, physics, 2011, Sep-01, Volume: 81, Issue:1

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neoplasms; Carmustine; Colorado;

2011
Favorable prognosis in patients with high-grade glioma with radiation necrosis: the University of Colorado reoperation series.
    International journal of radiation oncology, biology, physics, 2011, Sep-01, Volume: 81, Issue:1

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neoplasms; Carmustine; Colorado;

2011
Gamma-secretase inhibitors enhance temozolomide treatment of human gliomas by inhibiting neurosphere repopulation and xenograft recurrence.
    Cancer research, 2010, Sep-01, Volume: 70, Issue:17

    Topics: Amyloid Precursor Protein Secretases; Animals; Antineoplastic Agents, Alkylating; Antineoplastic Com

2010
Gamma-secretase inhibitors enhance temozolomide treatment of human gliomas by inhibiting neurosphere repopulation and xenograft recurrence.
    Cancer research, 2010, Sep-01, Volume: 70, Issue:17

    Topics: Amyloid Precursor Protein Secretases; Animals; Antineoplastic Agents, Alkylating; Antineoplastic Com

2010
Gamma-secretase inhibitors enhance temozolomide treatment of human gliomas by inhibiting neurosphere repopulation and xenograft recurrence.
    Cancer research, 2010, Sep-01, Volume: 70, Issue:17

    Topics: Amyloid Precursor Protein Secretases; Animals; Antineoplastic Agents, Alkylating; Antineoplastic Com

2010
Combination of temozolomide with immunocytokine F16-IL2 for the treatment of glioblastoma.
    British journal of cancer, 2010, Sep-07, Volume: 103, Issue:6

    Topics: Animals; Antineoplastic Agents; Apoptosis; Brain Neoplasms; Cell Proliferation; Dacarbazine; Gliobla

2010
Combination of temozolomide with immunocytokine F16-IL2 for the treatment of glioblastoma.
    British journal of cancer, 2010, Sep-07, Volume: 103, Issue:6

    Topics: Animals; Antineoplastic Agents; Apoptosis; Brain Neoplasms; Cell Proliferation; Dacarbazine; Gliobla

2010
Combination of temozolomide with immunocytokine F16-IL2 for the treatment of glioblastoma.
    British journal of cancer, 2010, Sep-07, Volume: 103, Issue:6

    Topics: Animals; Antineoplastic Agents; Apoptosis; Brain Neoplasms; Cell Proliferation; Dacarbazine; Gliobla

2010
Aplastic anemia as a cause of death in a patient with glioblastoma multiforme treated with temozolomide.
    Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 2010, Volume: 186, Issue:8

    Topics: Anemia, Aplastic; Antineoplastic Agents, Alkylating; Blood Cell Count; Brain Neoplasms; Cause of Dea

2010
Aplastic anemia as a cause of death in a patient with glioblastoma multiforme treated with temozolomide.
    Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 2010, Volume: 186, Issue:8

    Topics: Anemia, Aplastic; Antineoplastic Agents, Alkylating; Blood Cell Count; Brain Neoplasms; Cause of Dea

2010
Aplastic anemia as a cause of death in a patient with glioblastoma multiforme treated with temozolomide.
    Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 2010, Volume: 186, Issue:8

    Topics: Anemia, Aplastic; Antineoplastic Agents, Alkylating; Blood Cell Count; Brain Neoplasms; Cause of Dea

2010
Low peripheral lymphocyte count before focal radiotherapy plus concomitant temozolomide predicts severe lymphopenia during malignant glioma treatment.
    Neurologia medico-chirurgica, 2010, Volume: 50, Issue:8

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant; Combined Mo

2010
Low peripheral lymphocyte count before focal radiotherapy plus concomitant temozolomide predicts severe lymphopenia during malignant glioma treatment.
    Neurologia medico-chirurgica, 2010, Volume: 50, Issue:8

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant; Combined Mo

2010
Low peripheral lymphocyte count before focal radiotherapy plus concomitant temozolomide predicts severe lymphopenia during malignant glioma treatment.
    Neurologia medico-chirurgica, 2010, Volume: 50, Issue:8

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant; Combined Mo

2010
Brain metastasis of undifferentiated sarcoma and response to temozolomide treatment. Case report.
    Neurologia medico-chirurgica, 2010, Volume: 50, Issue:8

    Topics: Adult; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; D

2010
Brain metastasis of undifferentiated sarcoma and response to temozolomide treatment. Case report.
    Neurologia medico-chirurgica, 2010, Volume: 50, Issue:8

    Topics: Adult; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; D

2010
Brain metastasis of undifferentiated sarcoma and response to temozolomide treatment. Case report.
    Neurologia medico-chirurgica, 2010, Volume: 50, Issue:8

    Topics: Adult; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; D

2010
In vitro novel combinations of psychotropics and anti-cancer modalities in U87 human glioblastoma cells.
    International journal of oncology, 2010, Volume: 37, Issue:4

    Topics: Adenosine Triphosphate; Antineoplastic Combined Chemotherapy Protocols; Benzamides; Brain Neoplasms;

2010
In vitro novel combinations of psychotropics and anti-cancer modalities in U87 human glioblastoma cells.
    International journal of oncology, 2010, Volume: 37, Issue:4

    Topics: Adenosine Triphosphate; Antineoplastic Combined Chemotherapy Protocols; Benzamides; Brain Neoplasms;

2010
In vitro novel combinations of psychotropics and anti-cancer modalities in U87 human glioblastoma cells.
    International journal of oncology, 2010, Volume: 37, Issue:4

    Topics: Adenosine Triphosphate; Antineoplastic Combined Chemotherapy Protocols; Benzamides; Brain Neoplasms;

2010
Feasibility study of 21-day-on/7-day-off temozolomide in children with brain tumors.
    Journal of neuro-oncology, 2011, Volume: 103, Issue:1

    Topics: Adolescent; Antineoplastic Agents, Alkylating; Brain Neoplasms; Child; Child, Preschool; Dacarbazine

2011
Feasibility study of 21-day-on/7-day-off temozolomide in children with brain tumors.
    Journal of neuro-oncology, 2011, Volume: 103, Issue:1

    Topics: Adolescent; Antineoplastic Agents, Alkylating; Brain Neoplasms; Child; Child, Preschool; Dacarbazine

2011
Feasibility study of 21-day-on/7-day-off temozolomide in children with brain tumors.
    Journal of neuro-oncology, 2011, Volume: 103, Issue:1

    Topics: Adolescent; Antineoplastic Agents, Alkylating; Brain Neoplasms; Child; Child, Preschool; Dacarbazine

2011
Temozolomide/PLGA microparticles plus vatalanib inhibits tumor growth and angiogenesis in an orthotopic glioma model.
    European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 2010, Volume: 76, Issue:3

    Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protoc

2010
Temozolomide/PLGA microparticles plus vatalanib inhibits tumor growth and angiogenesis in an orthotopic glioma model.
    European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 2010, Volume: 76, Issue:3

    Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protoc

2010
Temozolomide/PLGA microparticles plus vatalanib inhibits tumor growth and angiogenesis in an orthotopic glioma model.
    European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 2010, Volume: 76, Issue:3

    Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protoc

2010
Long-term in vitro treatment of human glioblastoma cells with temozolomide increases resistance in vivo through up-regulation of GLUT transporter and aldo-keto reductase enzyme AKR1C expression.
    Neoplasia (New York, N.Y.), 2010, Volume: 12, Issue:9

    Topics: Alcohol Oxidoreductases; Aldehyde Reductase; Aldo-Keto Reductases; Animals; Antineoplastic Agents, A

2010
Long-term in vitro treatment of human glioblastoma cells with temozolomide increases resistance in vivo through up-regulation of GLUT transporter and aldo-keto reductase enzyme AKR1C expression.
    Neoplasia (New York, N.Y.), 2010, Volume: 12, Issue:9

    Topics: Alcohol Oxidoreductases; Aldehyde Reductase; Aldo-Keto Reductases; Animals; Antineoplastic Agents, A

2010
Long-term in vitro treatment of human glioblastoma cells with temozolomide increases resistance in vivo through up-regulation of GLUT transporter and aldo-keto reductase enzyme AKR1C expression.
    Neoplasia (New York, N.Y.), 2010, Volume: 12, Issue:9

    Topics: Alcohol Oxidoreductases; Aldehyde Reductase; Aldo-Keto Reductases; Animals; Antineoplastic Agents, A

2010
Correlation of MRI sequences to assess progressive glioblastoma multiforme treated with bevacizumab.
    Journal of neuro-oncology, 2011, Volume: 103, Issue:2

    Topics: Adult; Aged; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Antin

2011
Correlation of MRI sequences to assess progressive glioblastoma multiforme treated with bevacizumab.
    Journal of neuro-oncology, 2011, Volume: 103, Issue:2

    Topics: Adult; Aged; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Antin

2011
Correlation of MRI sequences to assess progressive glioblastoma multiforme treated with bevacizumab.
    Journal of neuro-oncology, 2011, Volume: 103, Issue:2

    Topics: Adult; Aged; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Antin

2011
Postoperative radiotherapy and concomitant temozolomide for elderly patients with glioblastoma.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2010, Volume: 97, Issue:3

    Topics: Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant;

2010
Postoperative radiotherapy and concomitant temozolomide for elderly patients with glioblastoma.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2010, Volume: 97, Issue:3

    Topics: Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant;

2010
Postoperative radiotherapy and concomitant temozolomide for elderly patients with glioblastoma.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2010, Volume: 97, Issue:3

    Topics: Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant;

2010
Patterns of failure and comparison of different target volume delineations in patients with glioblastoma treated with conformal radiotherapy plus concomitant and adjuvant temozolomide.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2010, Volume: 97, Issue:3

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant; Combined Mo

2010
Patterns of failure and comparison of different target volume delineations in patients with glioblastoma treated with conformal radiotherapy plus concomitant and adjuvant temozolomide.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2010, Volume: 97, Issue:3

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant; Combined Mo

2010
Patterns of failure and comparison of different target volume delineations in patients with glioblastoma treated with conformal radiotherapy plus concomitant and adjuvant temozolomide.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2010, Volume: 97, Issue:3

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant; Combined Mo

2010
Quantitative analysis of O6-methylguanine DNA methyltransferase (MGMT) promoter methylation in patients with low-grade gliomas.
    Journal of neuro-oncology, 2011, Volume: 103, Issue:2

    Topics: Adult; Aged; Antineoplastic Agents; Brain Neoplasms; Dacarbazine; Disease-Free Survival; DNA Methyla

2011
Quantitative analysis of O6-methylguanine DNA methyltransferase (MGMT) promoter methylation in patients with low-grade gliomas.
    Journal of neuro-oncology, 2011, Volume: 103, Issue:2

    Topics: Adult; Aged; Antineoplastic Agents; Brain Neoplasms; Dacarbazine; Disease-Free Survival; DNA Methyla

2011
Quantitative analysis of O6-methylguanine DNA methyltransferase (MGMT) promoter methylation in patients with low-grade gliomas.
    Journal of neuro-oncology, 2011, Volume: 103, Issue:2

    Topics: Adult; Aged; Antineoplastic Agents; Brain Neoplasms; Dacarbazine; Disease-Free Survival; DNA Methyla

2011
Predominant influence of MGMT methylation in non-resectable glioblastoma after radiotherapy plus temozolomide.
    Journal of neurology, neurosurgery, and psychiatry, 2011, Volume: 82, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modalit

2011
Predominant influence of MGMT methylation in non-resectable glioblastoma after radiotherapy plus temozolomide.
    Journal of neurology, neurosurgery, and psychiatry, 2011, Volume: 82, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modalit

2011
Predominant influence of MGMT methylation in non-resectable glioblastoma after radiotherapy plus temozolomide.
    Journal of neurology, neurosurgery, and psychiatry, 2011, Volume: 82, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modalit

2011
Temozolomide during and after radiation therapy for WHO grade III gliomas: preliminary report of a prospective multicenter study.
    Journal of neuro-oncology, 2011, Volume: 103, Issue:3

    Topics: Adolescent; Adult; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Da

2011
Temozolomide during and after radiation therapy for WHO grade III gliomas: preliminary report of a prospective multicenter study.
    Journal of neuro-oncology, 2011, Volume: 103, Issue:3

    Topics: Adolescent; Adult; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Da

2011
Temozolomide during and after radiation therapy for WHO grade III gliomas: preliminary report of a prospective multicenter study.
    Journal of neuro-oncology, 2011, Volume: 103, Issue:3

    Topics: Adolescent; Adult; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Da

2011
Urticarial hypersensitivity reaction caused by temozolomide.
    Journal of drugs in dermatology : JDD, 2010, Volume: 9, Issue:9

    Topics: Adult; Anti-Inflammatory Agents; Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neoplasms; Da

2010
Urticarial hypersensitivity reaction caused by temozolomide.
    Journal of drugs in dermatology : JDD, 2010, Volume: 9, Issue:9

    Topics: Adult; Anti-Inflammatory Agents; Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neoplasms; Da

2010
Urticarial hypersensitivity reaction caused by temozolomide.
    Journal of drugs in dermatology : JDD, 2010, Volume: 9, Issue:9

    Topics: Adult; Anti-Inflammatory Agents; Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neoplasms; Da

2010
Leptomeningeal metastases from small cell lung cancer responsive to temozolomide therapy.
    Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer, 2010, Volume: 5, Issue:10

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Female; Humans; Lung Neoplasms; Mal

2010
Leptomeningeal metastases from small cell lung cancer responsive to temozolomide therapy.
    Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer, 2010, Volume: 5, Issue:10

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Female; Humans; Lung Neoplasms; Mal

2010
Leptomeningeal metastases from small cell lung cancer responsive to temozolomide therapy.
    Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer, 2010, Volume: 5, Issue:10

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Female; Humans; Lung Neoplasms; Mal

2010
High-field iMRI in glioblastoma surgery: improvement of resection radicality and survival for the patient?
    Acta neurochirurgica. Supplement, 2011, Volume: 109

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Diffusion Magnetic Resonance Imagin

2011
High-field iMRI in glioblastoma surgery: improvement of resection radicality and survival for the patient?
    Acta neurochirurgica. Supplement, 2011, Volume: 109

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Diffusion Magnetic Resonance Imagin

2011
High-field iMRI in glioblastoma surgery: improvement of resection radicality and survival for the patient?
    Acta neurochirurgica. Supplement, 2011, Volume: 109

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Diffusion Magnetic Resonance Imagin

2011
IDH1 or IDH2 mutations predict longer survival and response to temozolomide in low-grade gliomas.
    Neurology, 2010, Oct-26, Volume: 75, Issue:17

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chi-Square Distribution

2010
IDH1 or IDH2 mutations predict longer survival and response to temozolomide in low-grade gliomas.
    Neurology, 2010, Oct-26, Volume: 75, Issue:17

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chi-Square Distribution

2010
IDH1 or IDH2 mutations predict longer survival and response to temozolomide in low-grade gliomas.
    Neurology, 2010, Oct-26, Volume: 75, Issue:17

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chi-Square Distribution

2010
What role should cilengitide have in the treatment of glioblastoma?
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2010, Nov-20, Volume: 28, Issue:33

    Topics: Brain Neoplasms; Clinical Trials as Topic; Dacarbazine; Glioblastoma; Humans; Snake Venoms; Temozolo

2010
What role should cilengitide have in the treatment of glioblastoma?
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2010, Nov-20, Volume: 28, Issue:33

    Topics: Brain Neoplasms; Clinical Trials as Topic; Dacarbazine; Glioblastoma; Humans; Snake Venoms; Temozolo

2010
What role should cilengitide have in the treatment of glioblastoma?
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2010, Nov-20, Volume: 28, Issue:33

    Topics: Brain Neoplasms; Clinical Trials as Topic; Dacarbazine; Glioblastoma; Humans; Snake Venoms; Temozolo

2010
Irradiation and bevacizumab in high-grade glioma retreatment settings.
    International journal of radiation oncology, biology, physics, 2012, Jan-01, Volume: 82, Issue:1

    Topics: Adolescent; Adult; Aged; Analysis of Variance; Angiogenesis Inhibitors; Antibodies, Monoclonal, Huma

2012
Irradiation and bevacizumab in high-grade glioma retreatment settings.
    International journal of radiation oncology, biology, physics, 2012, Jan-01, Volume: 82, Issue:1

    Topics: Adolescent; Adult; Aged; Analysis of Variance; Angiogenesis Inhibitors; Antibodies, Monoclonal, Huma

2012
Irradiation and bevacizumab in high-grade glioma retreatment settings.
    International journal of radiation oncology, biology, physics, 2012, Jan-01, Volume: 82, Issue:1

    Topics: Adolescent; Adult; Aged; Analysis of Variance; Angiogenesis Inhibitors; Antibodies, Monoclonal, Huma

2012
Assessment of perfusion MRI-derived parameters in evaluating and predicting response to antiangiogenic therapy in patients with newly diagnosed glioblastoma.
    Neuro-oncology, 2011, Volume: 13, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant; Combined Modality Therap

2011
Assessment of perfusion MRI-derived parameters in evaluating and predicting response to antiangiogenic therapy in patients with newly diagnosed glioblastoma.
    Neuro-oncology, 2011, Volume: 13, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant; Combined Modality Therap

2011
Assessment of perfusion MRI-derived parameters in evaluating and predicting response to antiangiogenic therapy in patients with newly diagnosed glioblastoma.
    Neuro-oncology, 2011, Volume: 13, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant; Combined Modality Therap

2011
MGMT promoter methylation in pediatric high-grade gliomas.
    Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 2011, Volume: 27, Issue:1

    Topics: Antineoplastic Agents; Brain Neoplasms; Child; Combined Modality Therapy; Dacarbazine; DNA Methylati

2011
MGMT promoter methylation in pediatric high-grade gliomas.
    Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 2011, Volume: 27, Issue:1

    Topics: Antineoplastic Agents; Brain Neoplasms; Child; Combined Modality Therapy; Dacarbazine; DNA Methylati

2011
MGMT promoter methylation in pediatric high-grade gliomas.
    Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 2011, Volume: 27, Issue:1

    Topics: Antineoplastic Agents; Brain Neoplasms; Child; Combined Modality Therapy; Dacarbazine; DNA Methylati

2011
Fractionated stereotactic reirradiation and concurrent temozolomide in patients with recurrent glioblastoma.
    Journal of neuro-oncology, 2011, Volume: 103, Issue:3

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbaz

2011
Fractionated stereotactic reirradiation and concurrent temozolomide in patients with recurrent glioblastoma.
    Journal of neuro-oncology, 2011, Volume: 103, Issue:3

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbaz

2011
Fractionated stereotactic reirradiation and concurrent temozolomide in patients with recurrent glioblastoma.
    Journal of neuro-oncology, 2011, Volume: 103, Issue:3

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbaz

2011
Radiographic patterns of relapse in glioblastoma.
    Journal of neuro-oncology, 2011, Volume: 101, Issue:2

    Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Mod

2011
Radiographic patterns of relapse in glioblastoma.
    Journal of neuro-oncology, 2011, Volume: 101, Issue:2

    Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Mod

2011
Radiographic patterns of relapse in glioblastoma.
    Journal of neuro-oncology, 2011, Volume: 101, Issue:2

    Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Mod

2011
Clinical significance of molecular biomarkers in glioblastoma.
    The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques, 2010, Volume: 37, Issue:5

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Biomarkers; Brain Neo

2010
Clinical significance of molecular biomarkers in glioblastoma.
    The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques, 2010, Volume: 37, Issue:5

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Biomarkers; Brain Neo

2010
Clinical significance of molecular biomarkers in glioblastoma.
    The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques, 2010, Volume: 37, Issue:5

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Biomarkers; Brain Neo

2010
Usefulness of MS-MLPA for detection of MGMT promoter methylation in the evaluation of pseudoprogression in glioblastoma patients.
    Neuro-oncology, 2011, Volume: 13, Issue:2

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Disease Progression; D

2011
Usefulness of MS-MLPA for detection of MGMT promoter methylation in the evaluation of pseudoprogression in glioblastoma patients.
    Neuro-oncology, 2011, Volume: 13, Issue:2

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Disease Progression; D

2011
Usefulness of MS-MLPA for detection of MGMT promoter methylation in the evaluation of pseudoprogression in glioblastoma patients.
    Neuro-oncology, 2011, Volume: 13, Issue:2

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Disease Progression; D

2011
Neuro-oncology, a decade of temozolomide and beyond.
    Expert review of anticancer therapy, 2010, Volume: 10, Issue:11

    Topics: Antineoplastic Agents; Brain Neoplasms; Dacarbazine; Humans; Quality of Life; Temozolomide; Treatmen

2010
Neuro-oncology, a decade of temozolomide and beyond.
    Expert review of anticancer therapy, 2010, Volume: 10, Issue:11

    Topics: Antineoplastic Agents; Brain Neoplasms; Dacarbazine; Humans; Quality of Life; Temozolomide; Treatmen

2010
Neuro-oncology, a decade of temozolomide and beyond.
    Expert review of anticancer therapy, 2010, Volume: 10, Issue:11

    Topics: Antineoplastic Agents; Brain Neoplasms; Dacarbazine; Humans; Quality of Life; Temozolomide; Treatmen

2010
Synergistic therapeutic effects of cytokine-induced killer cells and temozolomide against glioblastoma.
    Oncology reports, 2011, Volume: 25, Issue:1

    Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Combined Modality Therapy; Cytokine-Induced Killer

2011
Synergistic therapeutic effects of cytokine-induced killer cells and temozolomide against glioblastoma.
    Oncology reports, 2011, Volume: 25, Issue:1

    Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Combined Modality Therapy; Cytokine-Induced Killer

2011
Synergistic therapeutic effects of cytokine-induced killer cells and temozolomide against glioblastoma.
    Oncology reports, 2011, Volume: 25, Issue:1

    Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Combined Modality Therapy; Cytokine-Induced Killer

2011
Advances in translational research provide a rationale for clinical re-evaluation of high-dose radiotherapy for glioblastoma.
    Medical hypotheses, 2011, Volume: 76, Issue:3

    Topics: Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms;

2011
Advances in translational research provide a rationale for clinical re-evaluation of high-dose radiotherapy for glioblastoma.
    Medical hypotheses, 2011, Volume: 76, Issue:3

    Topics: Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms;

2011
Advances in translational research provide a rationale for clinical re-evaluation of high-dose radiotherapy for glioblastoma.
    Medical hypotheses, 2011, Volume: 76, Issue:3

    Topics: Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms;

2011
Taming glioblastoma by targeting angiogenesis: 3 years later.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2011, Jan-10, Volume: 29, Issue:2

    Topics: Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic A

2011
Taming glioblastoma by targeting angiogenesis: 3 years later.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2011, Jan-10, Volume: 29, Issue:2

    Topics: Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic A

2011
Taming glioblastoma by targeting angiogenesis: 3 years later.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2011, Jan-10, Volume: 29, Issue:2

    Topics: Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic A

2011
Non-stem cell origin for oligodendroglioma.
    Cancer cell, 2010, Dec-14, Volume: 18, Issue:6

    Topics: Animals; Antigens; Benzamides; Brain Neoplasms; Cell Differentiation; Cell Line, Tumor; Dacarbazine;

2010
Non-stem cell origin for oligodendroglioma.
    Cancer cell, 2010, Dec-14, Volume: 18, Issue:6

    Topics: Animals; Antigens; Benzamides; Brain Neoplasms; Cell Differentiation; Cell Line, Tumor; Dacarbazine;

2010
Non-stem cell origin for oligodendroglioma.
    Cancer cell, 2010, Dec-14, Volume: 18, Issue:6

    Topics: Animals; Antigens; Benzamides; Brain Neoplasms; Cell Differentiation; Cell Line, Tumor; Dacarbazine;

2010
First-line temozolomide chemotherapy in progressive low-grade astrocytomas after radiotherapy: molecular characteristics in relation to response.
    Neuro-oncology, 2011, Volume: 13, Issue:2

    Topics: Adult; Antineoplastic Agents, Alkylating; Astrocytoma; Biomarkers, Tumor; Brain Neoplasms; Chromosom

2011
First-line temozolomide chemotherapy in progressive low-grade astrocytomas after radiotherapy: molecular characteristics in relation to response.
    Neuro-oncology, 2011, Volume: 13, Issue:2

    Topics: Adult; Antineoplastic Agents, Alkylating; Astrocytoma; Biomarkers, Tumor; Brain Neoplasms; Chromosom

2011
First-line temozolomide chemotherapy in progressive low-grade astrocytomas after radiotherapy: molecular characteristics in relation to response.
    Neuro-oncology, 2011, Volume: 13, Issue:2

    Topics: Adult; Antineoplastic Agents, Alkylating; Astrocytoma; Biomarkers, Tumor; Brain Neoplasms; Chromosom

2011
Radiotherapy and temozolomide for newly diagnosed glioblastoma and anaplastic astrocytoma: validation of Radiation Therapy Oncology Group-Recursive Partitioning Analysis in the IMRT and temozolomide era.
    Journal of neuro-oncology, 2011, Volume: 104, Issue:1

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neoplasms; Chi-Square Distributio

2011
Radiotherapy and temozolomide for newly diagnosed glioblastoma and anaplastic astrocytoma: validation of Radiation Therapy Oncology Group-Recursive Partitioning Analysis in the IMRT and temozolomide era.
    Journal of neuro-oncology, 2011, Volume: 104, Issue:1

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neoplasms; Chi-Square Distributio

2011
Radiotherapy and temozolomide for newly diagnosed glioblastoma and anaplastic astrocytoma: validation of Radiation Therapy Oncology Group-Recursive Partitioning Analysis in the IMRT and temozolomide era.
    Journal of neuro-oncology, 2011, Volume: 104, Issue:1

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neoplasms; Chi-Square Distributio

2011
Case of atypical teratoid/rhabdoid tumor in an adult, with long survival.
    Brain tumor pathology, 2011, Volume: 28, Issue:1

    Topics: Adult; Biomarkers, Tumor; Brain Neoplasms; Chromosomal Proteins, Non-Histone; Combined Modality Ther

2011
Case of atypical teratoid/rhabdoid tumor in an adult, with long survival.
    Brain tumor pathology, 2011, Volume: 28, Issue:1

    Topics: Adult; Biomarkers, Tumor; Brain Neoplasms; Chromosomal Proteins, Non-Histone; Combined Modality Ther

2011
Case of atypical teratoid/rhabdoid tumor in an adult, with long survival.
    Brain tumor pathology, 2011, Volume: 28, Issue:1

    Topics: Adult; Biomarkers, Tumor; Brain Neoplasms; Chromosomal Proteins, Non-Histone; Combined Modality Ther

2011
Intracranial microcapsule drug delivery device for the treatment of an experimental gliosarcoma model.
    Biomaterials, 2011, Volume: 32, Issue:10

    Topics: Animals; Brain; Brain Neoplasms; Capsules; Dacarbazine; Disease Models, Animal; Drug Delivery System

2011
Intracranial microcapsule drug delivery device for the treatment of an experimental gliosarcoma model.
    Biomaterials, 2011, Volume: 32, Issue:10

    Topics: Animals; Brain; Brain Neoplasms; Capsules; Dacarbazine; Disease Models, Animal; Drug Delivery System

2011
Intracranial microcapsule drug delivery device for the treatment of an experimental gliosarcoma model.
    Biomaterials, 2011, Volume: 32, Issue:10

    Topics: Animals; Brain; Brain Neoplasms; Capsules; Dacarbazine; Disease Models, Animal; Drug Delivery System

2011
A combined preclinical therapy of cannabinoids and temozolomide against glioma.
    Molecular cancer therapeutics, 2011, Volume: 10, Issue:1

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Autophagy; Brain Neoplasms; Cell Growth Pro

2011
A combined preclinical therapy of cannabinoids and temozolomide against glioma.
    Molecular cancer therapeutics, 2011, Volume: 10, Issue:1

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Autophagy; Brain Neoplasms; Cell Growth Pro

2011
A combined preclinical therapy of cannabinoids and temozolomide against glioma.
    Molecular cancer therapeutics, 2011, Volume: 10, Issue:1

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Autophagy; Brain Neoplasms; Cell Growth Pro

2011
Dural venous sinus thrombosis in anaplastic astrocytoma following concurrent temozolomide and focal brain radiotherapy plus bevacizumab.
    Journal of neuro-oncology, 2011, Volume: 104, Issue:2

    Topics: Adult; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Astrocytom

2011
Dural venous sinus thrombosis in anaplastic astrocytoma following concurrent temozolomide and focal brain radiotherapy plus bevacizumab.
    Journal of neuro-oncology, 2011, Volume: 104, Issue:2

    Topics: Adult; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Astrocytom

2011
Dural venous sinus thrombosis in anaplastic astrocytoma following concurrent temozolomide and focal brain radiotherapy plus bevacizumab.
    Journal of neuro-oncology, 2011, Volume: 104, Issue:2

    Topics: Adult; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Astrocytom

2011
Impact of temozolomide chemotherapy on seizure frequency in patients with low-grade gliomas.
    Journal of neurosurgery, 2011, Volume: 114, Issue:6

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chi-Square Distribution; Dacarbazin

2011
Impact of temozolomide chemotherapy on seizure frequency in patients with low-grade gliomas.
    Journal of neurosurgery, 2011, Volume: 114, Issue:6

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chi-Square Distribution; Dacarbazin

2011
Impact of temozolomide chemotherapy on seizure frequency in patients with low-grade gliomas.
    Journal of neurosurgery, 2011, Volume: 114, Issue:6

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chi-Square Distribution; Dacarbazin

2011
Lonafarnib (SCH66336) improves the activity of temozolomide and radiation for orthotopic malignant gliomas.
    Journal of neuro-oncology, 2011, Volume: 104, Issue:1

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; D

2011
Lonafarnib (SCH66336) improves the activity of temozolomide and radiation for orthotopic malignant gliomas.
    Journal of neuro-oncology, 2011, Volume: 104, Issue:1

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; D

2011
Lonafarnib (SCH66336) improves the activity of temozolomide and radiation for orthotopic malignant gliomas.
    Journal of neuro-oncology, 2011, Volume: 104, Issue:1

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; D

2011
Green tea epigallocatechin gallate enhances therapeutic efficacy of temozolomide in orthotopic mouse glioblastoma models.
    Cancer letters, 2011, Mar-28, Volume: 302, Issue:2

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Camellia sinensis; Catechin; Cell Line,

2011
Green tea epigallocatechin gallate enhances therapeutic efficacy of temozolomide in orthotopic mouse glioblastoma models.
    Cancer letters, 2011, Mar-28, Volume: 302, Issue:2

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Camellia sinensis; Catechin; Cell Line,

2011
Green tea epigallocatechin gallate enhances therapeutic efficacy of temozolomide in orthotopic mouse glioblastoma models.
    Cancer letters, 2011, Mar-28, Volume: 302, Issue:2

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Camellia sinensis; Catechin; Cell Line,

2011
Induction of autophagy in temozolomide treated malignant gliomas.
    Neuropathology : official journal of the Japanese Society of Neuropathology, 2011, Volume: 31, Issue:5

    Topics: Adolescent; Adult; Aged; Autophagy; Brain Neoplasms; Child; Child, Preschool; Dacarbazine; Female; G

2011
Induction of autophagy in temozolomide treated malignant gliomas.
    Neuropathology : official journal of the Japanese Society of Neuropathology, 2011, Volume: 31, Issue:5

    Topics: Adolescent; Adult; Aged; Autophagy; Brain Neoplasms; Child; Child, Preschool; Dacarbazine; Female; G

2011
Induction of autophagy in temozolomide treated malignant gliomas.
    Neuropathology : official journal of the Japanese Society of Neuropathology, 2011, Volume: 31, Issue:5

    Topics: Adolescent; Adult; Aged; Autophagy; Brain Neoplasms; Child; Child, Preschool; Dacarbazine; Female; G

2011
Clinical features, management and outcomes of high-grade glioma patients in Ramathibodi Hospital.
    Journal of the Medical Association of Thailand = Chotmaihet thangphaet, 2010, Volume: 93 Suppl 2

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Carmustine; Combined Mo

2010
Clinical features, management and outcomes of high-grade glioma patients in Ramathibodi Hospital.
    Journal of the Medical Association of Thailand = Chotmaihet thangphaet, 2010, Volume: 93 Suppl 2

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Carmustine; Combined Mo

2010
Clinical features, management and outcomes of high-grade glioma patients in Ramathibodi Hospital.
    Journal of the Medical Association of Thailand = Chotmaihet thangphaet, 2010, Volume: 93 Suppl 2

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Carmustine; Combined Mo

2010
Retrospective comparison of chemoradiotherapy followed by adjuvant chemotherapy, with or without prior gliadel implantation (carmustine) after initial surgery in patients with newly diagnosed high-grade gliomas.
    International journal of radiation oncology, biology, physics, 2012, Feb-01, Volume: 82, Issue:2

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Antineoplastic Combin

2012
Retrospective comparison of chemoradiotherapy followed by adjuvant chemotherapy, with or without prior gliadel implantation (carmustine) after initial surgery in patients with newly diagnosed high-grade gliomas.
    International journal of radiation oncology, biology, physics, 2012, Feb-01, Volume: 82, Issue:2

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Antineoplastic Combin

2012
Retrospective comparison of chemoradiotherapy followed by adjuvant chemotherapy, with or without prior gliadel implantation (carmustine) after initial surgery in patients with newly diagnosed high-grade gliomas.
    International journal of radiation oncology, biology, physics, 2012, Feb-01, Volume: 82, Issue:2

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Antineoplastic Combin

2012
Prognostic factors for patients with gliomatosis cerebri: retrospective analysis of 17 consecutive cases.
    Neurosurgical review, 2010, Volume: 34, Issue:2

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Biopsy; Brain Neo

2010
Prognostic factors for patients with gliomatosis cerebri: retrospective analysis of 17 consecutive cases.
    Neurosurgical review, 2010, Volume: 34, Issue:2

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Biopsy; Brain Neo

2010
Prognostic factors for patients with gliomatosis cerebri: retrospective analysis of 17 consecutive cases.
    Neurosurgical review, 2010, Volume: 34, Issue:2

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Biopsy; Brain Neo

2010
Inhibition of PI3K/mTOR pathways in glioblastoma and implications for combination therapy with temozolomide.
    Neuro-oncology, 2011, Volume: 13, Issue:4

    Topics: Animals; Antineoplastic Agents, Alkylating; Blotting, Western; Brain Neoplasms; Cell Line, Tumor; Ce

2011
Inhibition of PI3K/mTOR pathways in glioblastoma and implications for combination therapy with temozolomide.
    Neuro-oncology, 2011, Volume: 13, Issue:4

    Topics: Animals; Antineoplastic Agents, Alkylating; Blotting, Western; Brain Neoplasms; Cell Line, Tumor; Ce

2011
Inhibition of PI3K/mTOR pathways in glioblastoma and implications for combination therapy with temozolomide.
    Neuro-oncology, 2011, Volume: 13, Issue:4

    Topics: Animals; Antineoplastic Agents, Alkylating; Blotting, Western; Brain Neoplasms; Cell Line, Tumor; Ce

2011
TMZ-induced PrPc/par-4 interaction promotes the survival of human glioma cells.
    International journal of cancer, 2012, Jan-15, Volume: 130, Issue:2

    Topics: Animals; Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cell Cycle; Cell Line, Tumor

2012
TMZ-induced PrPc/par-4 interaction promotes the survival of human glioma cells.
    International journal of cancer, 2012, Jan-15, Volume: 130, Issue:2

    Topics: Animals; Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cell Cycle; Cell Line, Tumor

2012
TMZ-induced PrPc/par-4 interaction promotes the survival of human glioma cells.
    International journal of cancer, 2012, Jan-15, Volume: 130, Issue:2

    Topics: Animals; Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cell Cycle; Cell Line, Tumor

2012
GRP78/BiP modulation of GRP78/BiP in altering sensitivity to chemotherapy.
    Methods in enzymology, 2011, Volume: 491

    Topics: Activating Transcription Factor 6; Animals; Antineoplastic Agents; Brain Neoplasms; Catechin; Cell L

2011
GRP78/BiP modulation of GRP78/BiP in altering sensitivity to chemotherapy.
    Methods in enzymology, 2011, Volume: 491

    Topics: Activating Transcription Factor 6; Animals; Antineoplastic Agents; Brain Neoplasms; Catechin; Cell L

2011
GRP78/BiP modulation of GRP78/BiP in altering sensitivity to chemotherapy.
    Methods in enzymology, 2011, Volume: 491

    Topics: Activating Transcription Factor 6; Animals; Antineoplastic Agents; Brain Neoplasms; Catechin; Cell L

2011
O6-methylguanine DNA methyltransferase expression in tumor cells predicts outcome of radiotherapy plus concomitant and adjuvant temozolomide therapy in patients with primary glioblastoma.
    Brain tumor pathology, 2011, Volume: 28, Issue:2

    Topics: Adult; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Biomarkers

2011
O6-methylguanine DNA methyltransferase expression in tumor cells predicts outcome of radiotherapy plus concomitant and adjuvant temozolomide therapy in patients with primary glioblastoma.
    Brain tumor pathology, 2011, Volume: 28, Issue:2

    Topics: Adult; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Biomarkers

2011
O6-methylguanine DNA methyltransferase expression in tumor cells predicts outcome of radiotherapy plus concomitant and adjuvant temozolomide therapy in patients with primary glioblastoma.
    Brain tumor pathology, 2011, Volume: 28, Issue:2

    Topics: Adult; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Biomarkers

2011
Immune modulation effects of concomitant temozolomide and radiation therapy on peripheral blood mononuclear cells in patients with glioblastoma multiforme.
    Neuro-oncology, 2011, Volume: 13, Issue:4

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Blood Cells; Brain Neoplasms; Combined Modality Ther

2011
Immune modulation effects of concomitant temozolomide and radiation therapy on peripheral blood mononuclear cells in patients with glioblastoma multiforme.
    Neuro-oncology, 2011, Volume: 13, Issue:4

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Blood Cells; Brain Neoplasms; Combined Modality Ther

2011
Immune modulation effects of concomitant temozolomide and radiation therapy on peripheral blood mononuclear cells in patients with glioblastoma multiforme.
    Neuro-oncology, 2011, Volume: 13, Issue:4

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Blood Cells; Brain Neoplasms; Combined Modality Ther

2011
Neural stem/progenitors and glioma stem-like cells have differential sensitivity to chemotherapy.
    Neurology, 2011, Mar-29, Volume: 76, Issue:13

    Topics: Animals; Antineoplastic Agents; Apoptosis; Boronic Acids; Bortezomib; Brain Neoplasms; Caspase 3; Ce

2011
Neural stem/progenitors and glioma stem-like cells have differential sensitivity to chemotherapy.
    Neurology, 2011, Mar-29, Volume: 76, Issue:13

    Topics: Animals; Antineoplastic Agents; Apoptosis; Boronic Acids; Bortezomib; Brain Neoplasms; Caspase 3; Ce

2011
Neural stem/progenitors and glioma stem-like cells have differential sensitivity to chemotherapy.
    Neurology, 2011, Mar-29, Volume: 76, Issue:13

    Topics: Animals; Antineoplastic Agents; Apoptosis; Boronic Acids; Bortezomib; Brain Neoplasms; Caspase 3; Ce

2011
Rad51 inhibition is an effective means of targeting DNA repair in glioma models and CD133+ tumor-derived cells.
    Neuro-oncology, 2011, Volume: 13, Issue:5

    Topics: AC133 Antigen; Antigens, CD; Antineoplastic Agents, Alkylating; Apoptosis; Blotting, Western; Brain

2011
Rad51 inhibition is an effective means of targeting DNA repair in glioma models and CD133+ tumor-derived cells.
    Neuro-oncology, 2011, Volume: 13, Issue:5

    Topics: AC133 Antigen; Antigens, CD; Antineoplastic Agents, Alkylating; Apoptosis; Blotting, Western; Brain

2011
Rad51 inhibition is an effective means of targeting DNA repair in glioma models and CD133+ tumor-derived cells.
    Neuro-oncology, 2011, Volume: 13, Issue:5

    Topics: AC133 Antigen; Antigens, CD; Antineoplastic Agents, Alkylating; Apoptosis; Blotting, Western; Brain

2011
O-methylguanine-DNA methyltransferase (MGMT) mRNA expression predicts outcome in malignant glioma independent of MGMT promoter methylation.
    PloS one, 2011, Feb-18, Volume: 6, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Ad

2011
O-methylguanine-DNA methyltransferase (MGMT) mRNA expression predicts outcome in malignant glioma independent of MGMT promoter methylation.
    PloS one, 2011, Feb-18, Volume: 6, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Ad

2011
O-methylguanine-DNA methyltransferase (MGMT) mRNA expression predicts outcome in malignant glioma independent of MGMT promoter methylation.
    PloS one, 2011, Feb-18, Volume: 6, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Ad

2011
N-methylpurine DNA glycosylase and DNA polymerase beta modulate BER inhibitor potentiation of glioma cells to temozolomide.
    Neuro-oncology, 2011, Volume: 13, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Apoptosis; Blotting, Western; Brain; Brain Neoplasms; Cell Line,

2011
N-methylpurine DNA glycosylase and DNA polymerase beta modulate BER inhibitor potentiation of glioma cells to temozolomide.
    Neuro-oncology, 2011, Volume: 13, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Apoptosis; Blotting, Western; Brain; Brain Neoplasms; Cell Line,

2011
N-methylpurine DNA glycosylase and DNA polymerase beta modulate BER inhibitor potentiation of glioma cells to temozolomide.
    Neuro-oncology, 2011, Volume: 13, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Apoptosis; Blotting, Western; Brain; Brain Neoplasms; Cell Line,

2011
Comparison of corticotropin-releasing factor, dexamethasone, and temozolomide: treatment efficacy and toxicity in U87 and C6 intracranial gliomas.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2011, May-15, Volume: 17, Issue:10

    Topics: Animals; Antineoplastic Agents; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Corticotropin-Releasin

2011
Comparison of corticotropin-releasing factor, dexamethasone, and temozolomide: treatment efficacy and toxicity in U87 and C6 intracranial gliomas.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2011, May-15, Volume: 17, Issue:10

    Topics: Animals; Antineoplastic Agents; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Corticotropin-Releasin

2011
Comparison of corticotropin-releasing factor, dexamethasone, and temozolomide: treatment efficacy and toxicity in U87 and C6 intracranial gliomas.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2011, May-15, Volume: 17, Issue:10

    Topics: Animals; Antineoplastic Agents; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Corticotropin-Releasin

2011
Pseudoprogression in patients with glioblastoma multiforme after concurrent radiotherapy and temozolomide.
    American journal of clinical oncology, 2012, Volume: 35, Issue:3

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant;

2012
Pseudoprogression in patients with glioblastoma multiforme after concurrent radiotherapy and temozolomide.
    American journal of clinical oncology, 2012, Volume: 35, Issue:3

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant;

2012
Pseudoprogression in patients with glioblastoma multiforme after concurrent radiotherapy and temozolomide.
    American journal of clinical oncology, 2012, Volume: 35, Issue:3

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant;

2012
Temozolomide-induced modification of the CXC chemokine network in experimental gliomas.
    International journal of oncology, 2011, Volume: 38, Issue:5

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Chemokines, CXC; Daca

2011
Temozolomide-induced modification of the CXC chemokine network in experimental gliomas.
    International journal of oncology, 2011, Volume: 38, Issue:5

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Chemokines, CXC; Daca

2011
Temozolomide-induced modification of the CXC chemokine network in experimental gliomas.
    International journal of oncology, 2011, Volume: 38, Issue:5

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Chemokines, CXC; Daca

2011
Temozolomide induced c-Myc-mediated apoptosis via Akt signalling in MGMT expressing glioblastoma cells.
    International journal of radiation biology, 2011, Volume: 87, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cell Cycle; Cell Line, Tumor; Dacarba

2011
Temozolomide induced c-Myc-mediated apoptosis via Akt signalling in MGMT expressing glioblastoma cells.
    International journal of radiation biology, 2011, Volume: 87, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cell Cycle; Cell Line, Tumor; Dacarba

2011
Temozolomide induced c-Myc-mediated apoptosis via Akt signalling in MGMT expressing glioblastoma cells.
    International journal of radiation biology, 2011, Volume: 87, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cell Cycle; Cell Line, Tumor; Dacarba

2011
Can the therapeutic effects of temozolomide be potentiated by stimulating AMP-activated protein kinase with olanzepine and metformin?
    British journal of pharmacology, 2011, Volume: 164, Issue:5

    Topics: AMP-Activated Protein Kinases; Animals; Antineoplastic Agents, Alkylating; Apoptosis; Benzodiazepine

2011
Can the therapeutic effects of temozolomide be potentiated by stimulating AMP-activated protein kinase with olanzepine and metformin?
    British journal of pharmacology, 2011, Volume: 164, Issue:5

    Topics: AMP-Activated Protein Kinases; Animals; Antineoplastic Agents, Alkylating; Apoptosis; Benzodiazepine

2011
Can the therapeutic effects of temozolomide be potentiated by stimulating AMP-activated protein kinase with olanzepine and metformin?
    British journal of pharmacology, 2011, Volume: 164, Issue:5

    Topics: AMP-Activated Protein Kinases; Animals; Antineoplastic Agents, Alkylating; Apoptosis; Benzodiazepine

2011
[Comparison of MGMT and ERCC₂ expression in temozolomide for the treatment of malignant glioma drug resistance and their genetic relationship].
    Zhonghua yi xue za zhi, 2011, Jan-04, Volume: 91, Issue:1

    Topics: Adult; Aged; Brain Neoplasms; Dacarbazine; Drug Resistance, Neoplasm; Female; Gene Expression; Genes

2011
[Comparison of MGMT and ERCC₂ expression in temozolomide for the treatment of malignant glioma drug resistance and their genetic relationship].
    Zhonghua yi xue za zhi, 2011, Jan-04, Volume: 91, Issue:1

    Topics: Adult; Aged; Brain Neoplasms; Dacarbazine; Drug Resistance, Neoplasm; Female; Gene Expression; Genes

2011
[Comparison of MGMT and ERCC₂ expression in temozolomide for the treatment of malignant glioma drug resistance and their genetic relationship].
    Zhonghua yi xue za zhi, 2011, Jan-04, Volume: 91, Issue:1

    Topics: Adult; Aged; Brain Neoplasms; Dacarbazine; Drug Resistance, Neoplasm; Female; Gene Expression; Genes

2011
Promoter methylation and expression of MGMT and the DNA mismatch repair genes MLH1, MSH2, MSH6 and PMS2 in paired primary and recurrent glioblastomas.
    International journal of cancer, 2011, Aug-01, Volume: 129, Issue:3

    Topics: Adaptor Proteins, Signal Transducing; Adenosine Triphosphatases; Adult; Aged; Antineoplastic Agents;

2011
Promoter methylation and expression of MGMT and the DNA mismatch repair genes MLH1, MSH2, MSH6 and PMS2 in paired primary and recurrent glioblastomas.
    International journal of cancer, 2011, Aug-01, Volume: 129, Issue:3

    Topics: Adaptor Proteins, Signal Transducing; Adenosine Triphosphatases; Adult; Aged; Antineoplastic Agents;

2011
Promoter methylation and expression of MGMT and the DNA mismatch repair genes MLH1, MSH2, MSH6 and PMS2 in paired primary and recurrent glioblastomas.
    International journal of cancer, 2011, Aug-01, Volume: 129, Issue:3

    Topics: Adaptor Proteins, Signal Transducing; Adenosine Triphosphatases; Adult; Aged; Antineoplastic Agents;

2011
Radiation-induced astrocytoma with rapid malignant transformation: case report.
    Neurologia medico-chirurgica, 2011, Volume: 51, Issue:3

    Topics: Antineoplastic Agents, Alkylating; Astrocytoma; Basal Ganglia; Brain Neoplasms; Cell Transformation,

2011
Radiation-induced astrocytoma with rapid malignant transformation: case report.
    Neurologia medico-chirurgica, 2011, Volume: 51, Issue:3

    Topics: Antineoplastic Agents, Alkylating; Astrocytoma; Basal Ganglia; Brain Neoplasms; Cell Transformation,

2011
Radiation-induced astrocytoma with rapid malignant transformation: case report.
    Neurologia medico-chirurgica, 2011, Volume: 51, Issue:3

    Topics: Antineoplastic Agents, Alkylating; Astrocytoma; Basal Ganglia; Brain Neoplasms; Cell Transformation,

2011
MGMT promoter methylation and temozolomide response in choroid plexus carcinoma.
    Brain tumor pathology, 2011, Volume: 28, Issue:3

    Topics: Adult; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy, Adjuvant; Choroid Plex

2011
MGMT promoter methylation and temozolomide response in choroid plexus carcinoma.
    Brain tumor pathology, 2011, Volume: 28, Issue:3

    Topics: Adult; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy, Adjuvant; Choroid Plex

2011
MGMT promoter methylation and temozolomide response in choroid plexus carcinoma.
    Brain tumor pathology, 2011, Volume: 28, Issue:3

    Topics: Adult; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy, Adjuvant; Choroid Plex

2011
Enhanced brain targeting of temozolomide in polysorbate-80 coated polybutylcyanoacrylate nanoparticles.
    International journal of nanomedicine, 2011, Volume: 6

    Topics: Animals; Blood-Brain Barrier; Brain; Brain Neoplasms; Dacarbazine; Microscopy, Electron, Transmissio

2011
Enhanced brain targeting of temozolomide in polysorbate-80 coated polybutylcyanoacrylate nanoparticles.
    International journal of nanomedicine, 2011, Volume: 6

    Topics: Animals; Blood-Brain Barrier; Brain; Brain Neoplasms; Dacarbazine; Microscopy, Electron, Transmissio

2011
Enhanced brain targeting of temozolomide in polysorbate-80 coated polybutylcyanoacrylate nanoparticles.
    International journal of nanomedicine, 2011, Volume: 6

    Topics: Animals; Blood-Brain Barrier; Brain; Brain Neoplasms; Dacarbazine; Microscopy, Electron, Transmissio

2011
[Benefit of a prolonged adjuvant treatment with temozolomide for the management of patients with glioblastoma].
    Cancer radiotherapie : journal de la Societe francaise de radiotherapie oncologique, 2011, Volume: 15, Issue:3

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant; Combined Mo

2011
[Benefit of a prolonged adjuvant treatment with temozolomide for the management of patients with glioblastoma].
    Cancer radiotherapie : journal de la Societe francaise de radiotherapie oncologique, 2011, Volume: 15, Issue:3

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant; Combined Mo

2011
[Benefit of a prolonged adjuvant treatment with temozolomide for the management of patients with glioblastoma].
    Cancer radiotherapie : journal de la Societe francaise de radiotherapie oncologique, 2011, Volume: 15, Issue:3

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant; Combined Mo

2011
Growth-inhibitory and chemosensitizing effects of the glutathione-S-transferase-π-activated nitric oxide donor PABA/NO in malignant gliomas.
    International journal of cancer, 2012, Mar-01, Volume: 130, Issue:5

    Topics: 4-Aminobenzoic Acid; Animals; Antineoplastic Combined Chemotherapy Protocols; Azo Compounds; Brain N

2012
Growth-inhibitory and chemosensitizing effects of the glutathione-S-transferase-π-activated nitric oxide donor PABA/NO in malignant gliomas.
    International journal of cancer, 2012, Mar-01, Volume: 130, Issue:5

    Topics: 4-Aminobenzoic Acid; Animals; Antineoplastic Combined Chemotherapy Protocols; Azo Compounds; Brain N

2012
Growth-inhibitory and chemosensitizing effects of the glutathione-S-transferase-π-activated nitric oxide donor PABA/NO in malignant gliomas.
    International journal of cancer, 2012, Mar-01, Volume: 130, Issue:5

    Topics: 4-Aminobenzoic Acid; Animals; Antineoplastic Combined Chemotherapy Protocols; Azo Compounds; Brain N

2012
A GATA4-regulated tumor suppressor network represses formation of malignant human astrocytomas.
    The Journal of experimental medicine, 2011, Apr-11, Volume: 208, Issue:4

    Topics: Animals; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Cyclin D1; Cyclin-Dependent Kinase I

2011
A GATA4-regulated tumor suppressor network represses formation of malignant human astrocytomas.
    The Journal of experimental medicine, 2011, Apr-11, Volume: 208, Issue:4

    Topics: Animals; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Cyclin D1; Cyclin-Dependent Kinase I

2011
A GATA4-regulated tumor suppressor network represses formation of malignant human astrocytomas.
    The Journal of experimental medicine, 2011, Apr-11, Volume: 208, Issue:4

    Topics: Animals; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Cyclin D1; Cyclin-Dependent Kinase I

2011
Benefits of interferon-β and temozolomide combination therapy for newly diagnosed primary glioblastoma with the unmethylated MGMT promoter: A multicenter study.
    Cancer, 2011, Apr-15, Volume: 117, Issue:8

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Brain Ne

2011
Benefits of interferon-β and temozolomide combination therapy for newly diagnosed primary glioblastoma with the unmethylated MGMT promoter: A multicenter study.
    Cancer, 2011, Apr-15, Volume: 117, Issue:8

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Brain Ne

2011
Benefits of interferon-β and temozolomide combination therapy for newly diagnosed primary glioblastoma with the unmethylated MGMT promoter: A multicenter study.
    Cancer, 2011, Apr-15, Volume: 117, Issue:8

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Brain Ne

2011
Cytoreductive surgery of glioblastoma as the key to successful adjuvant therapies: new arguments in an old discussion.
    Acta neurochirurgica, 2011, Volume: 153, Issue:6

    Topics: Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Carmustine; Chemotherapy, Adjuvant; Combin

2011
Cytoreductive surgery of glioblastoma as the key to successful adjuvant therapies: new arguments in an old discussion.
    Acta neurochirurgica, 2011, Volume: 153, Issue:6

    Topics: Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Carmustine; Chemotherapy, Adjuvant; Combin

2011
Cytoreductive surgery of glioblastoma as the key to successful adjuvant therapies: new arguments in an old discussion.
    Acta neurochirurgica, 2011, Volume: 153, Issue:6

    Topics: Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Carmustine; Chemotherapy, Adjuvant; Combin

2011
Safety and efficacy of stereotactic radiosurgery and adjuvant bevacizumab in patients with recurrent malignant gliomas.
    International journal of radiation oncology, biology, physics, 2012, Apr-01, Volume: 82, Issue:5

    Topics: Adult; Aged; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Antineoplastic Agents, Alky

2012
Safety and efficacy of stereotactic radiosurgery and adjuvant bevacizumab in patients with recurrent malignant gliomas.
    International journal of radiation oncology, biology, physics, 2012, Apr-01, Volume: 82, Issue:5

    Topics: Adult; Aged; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Antineoplastic Agents, Alky

2012
Safety and efficacy of stereotactic radiosurgery and adjuvant bevacizumab in patients with recurrent malignant gliomas.
    International journal of radiation oncology, biology, physics, 2012, Apr-01, Volume: 82, Issue:5

    Topics: Adult; Aged; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Antineoplastic Agents, Alky

2012
Prognostic impact of postoperative, pre-irradiation (18)F-fluoroethyl-l-tyrosine uptake in glioblastoma patients treated with radiochemotherapy.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2011, Volume: 99, Issue:2

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Contrast

2011
Prognostic impact of postoperative, pre-irradiation (18)F-fluoroethyl-l-tyrosine uptake in glioblastoma patients treated with radiochemotherapy.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2011, Volume: 99, Issue:2

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Contrast

2011
Prognostic impact of postoperative, pre-irradiation (18)F-fluoroethyl-l-tyrosine uptake in glioblastoma patients treated with radiochemotherapy.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2011, Volume: 99, Issue:2

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Contrast

2011
Response to temozolomide in supratentorial multifocal recurrence of malignant ependymoma.
    Anticancer research, 2011, Volume: 31, Issue:3

    Topics: Adult; Antineoplastic Agents; Brain Neoplasms; Dacarbazine; Disease Progression; Ependymoma; Female;

2011
Response to temozolomide in supratentorial multifocal recurrence of malignant ependymoma.
    Anticancer research, 2011, Volume: 31, Issue:3

    Topics: Adult; Antineoplastic Agents; Brain Neoplasms; Dacarbazine; Disease Progression; Ependymoma; Female;

2011
Response to temozolomide in supratentorial multifocal recurrence of malignant ependymoma.
    Anticancer research, 2011, Volume: 31, Issue:3

    Topics: Adult; Antineoplastic Agents; Brain Neoplasms; Dacarbazine; Disease Progression; Ependymoma; Female;

2011
Pathological changes after autologous formalin-fixed tumor vaccine therapy combined with temozolomide for glioblastoma - three case reports - .
    Neurologia medico-chirurgica, 2011, Volume: 51, Issue:4

    Topics: Adjuvants, Immunologic; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cancer Vacc

2011
Pathological changes after autologous formalin-fixed tumor vaccine therapy combined with temozolomide for glioblastoma - three case reports - .
    Neurologia medico-chirurgica, 2011, Volume: 51, Issue:4

    Topics: Adjuvants, Immunologic; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cancer Vacc

2011
Pathological changes after autologous formalin-fixed tumor vaccine therapy combined with temozolomide for glioblastoma - three case reports - .
    Neurologia medico-chirurgica, 2011, Volume: 51, Issue:4

    Topics: Adjuvants, Immunologic; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cancer Vacc

2011
Cediranib enhances control of wild type EGFR and EGFRvIII-expressing gliomas through potentiating temozolomide, but not through radiosensitization: implications for the clinic.
    Journal of neuro-oncology, 2011, Volume: 105, Issue:2

    Topics: Animals; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Brain Ne

2011
Cediranib enhances control of wild type EGFR and EGFRvIII-expressing gliomas through potentiating temozolomide, but not through radiosensitization: implications for the clinic.
    Journal of neuro-oncology, 2011, Volume: 105, Issue:2

    Topics: Animals; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Brain Ne

2011
Cediranib enhances control of wild type EGFR and EGFRvIII-expressing gliomas through potentiating temozolomide, but not through radiosensitization: implications for the clinic.
    Journal of neuro-oncology, 2011, Volume: 105, Issue:2

    Topics: Animals; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Brain Ne

2011
Seizure control: a secondary benefit of chemotherapeutic temozolomide in brain cancer patients.
    Epilepsy research, 2011, Volume: 95, Issue:3

    Topics: Adult; Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neoplasms; Dacarbazine; Electroencephal

2011
Seizure control: a secondary benefit of chemotherapeutic temozolomide in brain cancer patients.
    Epilepsy research, 2011, Volume: 95, Issue:3

    Topics: Adult; Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neoplasms; Dacarbazine; Electroencephal

2011
Seizure control: a secondary benefit of chemotherapeutic temozolomide in brain cancer patients.
    Epilepsy research, 2011, Volume: 95, Issue:3

    Topics: Adult; Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neoplasms; Dacarbazine; Electroencephal

2011
How fine a slice: treatment of newly diagnosed glioblastoma with an epidermal growth factor receptor variant III peptide vaccine.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2011, Jun-10, Volume: 29, Issue:17

    Topics: Brain Neoplasms; Cancer Vaccines; Combined Modality Therapy; Dacarbazine; DNA Methylation; DNA Modif

2011
How fine a slice: treatment of newly diagnosed glioblastoma with an epidermal growth factor receptor variant III peptide vaccine.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2011, Jun-10, Volume: 29, Issue:17

    Topics: Brain Neoplasms; Cancer Vaccines; Combined Modality Therapy; Dacarbazine; DNA Methylation; DNA Modif

2011
How fine a slice: treatment of newly diagnosed glioblastoma with an epidermal growth factor receptor variant III peptide vaccine.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2011, Jun-10, Volume: 29, Issue:17

    Topics: Brain Neoplasms; Cancer Vaccines; Combined Modality Therapy; Dacarbazine; DNA Methylation; DNA Modif

2011
Overall survival and extent of surgery in adult versus elderly glioblastoma patients: A population based retrospective study.
    Wiener klinische Wochenschrift, 2011, Volume: 123, Issue:11-12

    Topics: Adult; Age Factors; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Biopsy; Brain; Brain

2011
Overall survival and extent of surgery in adult versus elderly glioblastoma patients: A population based retrospective study.
    Wiener klinische Wochenschrift, 2011, Volume: 123, Issue:11-12

    Topics: Adult; Age Factors; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Biopsy; Brain; Brain

2011
Overall survival and extent of surgery in adult versus elderly glioblastoma patients: A population based retrospective study.
    Wiener klinische Wochenschrift, 2011, Volume: 123, Issue:11-12

    Topics: Adult; Age Factors; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Biopsy; Brain; Brain

2011
Detection of early response to temozolomide treatment in brain tumors using hyperpolarized 13C MR metabolic imaging.
    Journal of magnetic resonance imaging : JMRI, 2011, Volume: 33, Issue:6

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Carbon Isotopes; Cell Line, Tumor; Daca

2011
Detection of early response to temozolomide treatment in brain tumors using hyperpolarized 13C MR metabolic imaging.
    Journal of magnetic resonance imaging : JMRI, 2011, Volume: 33, Issue:6

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Carbon Isotopes; Cell Line, Tumor; Daca

2011
Detection of early response to temozolomide treatment in brain tumors using hyperpolarized 13C MR metabolic imaging.
    Journal of magnetic resonance imaging : JMRI, 2011, Volume: 33, Issue:6

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Carbon Isotopes; Cell Line, Tumor; Daca

2011
Primary gliosarcoma--clinical experience from a regional cancer centre in north India.
    British journal of neurosurgery, 2011, Volume: 25, Issue:6

    Topics: Adult; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cancer Care Facilities; Combined Modality

2011
Primary gliosarcoma--clinical experience from a regional cancer centre in north India.
    British journal of neurosurgery, 2011, Volume: 25, Issue:6

    Topics: Adult; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cancer Care Facilities; Combined Modality

2011
Primary gliosarcoma--clinical experience from a regional cancer centre in north India.
    British journal of neurosurgery, 2011, Volume: 25, Issue:6

    Topics: Adult; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cancer Care Facilities; Combined Modality

2011
Predicting the outcome of grade II glioma treated with temozolomide using proton magnetic resonance spectroscopy.
    British journal of cancer, 2011, Jun-07, Volume: 104, Issue:12

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Aspartic Acid; Brain Neoplasms; Choline; Creatine; D

2011
Predicting the outcome of grade II glioma treated with temozolomide using proton magnetic resonance spectroscopy.
    British journal of cancer, 2011, Jun-07, Volume: 104, Issue:12

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Aspartic Acid; Brain Neoplasms; Choline; Creatine; D

2011
Predicting the outcome of grade II glioma treated with temozolomide using proton magnetic resonance spectroscopy.
    British journal of cancer, 2011, Jun-07, Volume: 104, Issue:12

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Aspartic Acid; Brain Neoplasms; Choline; Creatine; D

2011
The effect of PTEN on proliferation and drug-, and radiosensitivity in malignant glioma cells.
    Anticancer research, 2011, Volume: 31, Issue:5

    Topics: Adenoviridae; Antineoplastic Agents, Alkylating; Apoptosis; Blotting, Western; Brain Neoplasms; Cell

2011
The effect of PTEN on proliferation and drug-, and radiosensitivity in malignant glioma cells.
    Anticancer research, 2011, Volume: 31, Issue:5

    Topics: Adenoviridae; Antineoplastic Agents, Alkylating; Apoptosis; Blotting, Western; Brain Neoplasms; Cell

2011
The effect of PTEN on proliferation and drug-, and radiosensitivity in malignant glioma cells.
    Anticancer research, 2011, Volume: 31, Issue:5

    Topics: Adenoviridae; Antineoplastic Agents, Alkylating; Apoptosis; Blotting, Western; Brain Neoplasms; Cell

2011
Leptomeningeal dissemination of anaplastic glioma: prolonged survival in two patients treated with temozolomide.
    Journal of neuro-oncology, 2011, Volume: 105, Issue:3

    Topics: Aged; Antineoplastic Agents; Brain Neoplasms; Dacarbazine; Glioma; Humans; Male; Meningeal Carcinoma

2011
Leptomeningeal dissemination of anaplastic glioma: prolonged survival in two patients treated with temozolomide.
    Journal of neuro-oncology, 2011, Volume: 105, Issue:3

    Topics: Aged; Antineoplastic Agents; Brain Neoplasms; Dacarbazine; Glioma; Humans; Male; Meningeal Carcinoma

2011
Leptomeningeal dissemination of anaplastic glioma: prolonged survival in two patients treated with temozolomide.
    Journal of neuro-oncology, 2011, Volume: 105, Issue:3

    Topics: Aged; Antineoplastic Agents; Brain Neoplasms; Dacarbazine; Glioma; Humans; Male; Meningeal Carcinoma

2011
International retrospective study of over 1000 adults with anaplastic oligodendroglial tumors.
    Neuro-oncology, 2011, Volume: 13, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Chr

2011
International retrospective study of over 1000 adults with anaplastic oligodendroglial tumors.
    Neuro-oncology, 2011, Volume: 13, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Chr

2011
International retrospective study of over 1000 adults with anaplastic oligodendroglial tumors.
    Neuro-oncology, 2011, Volume: 13, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Chr

2011
Rare phenomenon: liver metastases from glioblastoma multiforme.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2011, Aug-10, Volume: 29, Issue:23

    Topics: Aged; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Bevacizumab;

2011
Rare phenomenon: liver metastases from glioblastoma multiforme.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2011, Aug-10, Volume: 29, Issue:23

    Topics: Aged; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Bevacizumab;

2011
Rare phenomenon: liver metastases from glioblastoma multiforme.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2011, Aug-10, Volume: 29, Issue:23

    Topics: Aged; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Bevacizumab;

2011
Glioblastoma: patterns of recurrence and efficacy of salvage treatments.
    The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques, 2011, Volume: 38, Issue:4

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Disease Progression; F

2011
Glioblastoma: patterns of recurrence and efficacy of salvage treatments.
    The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques, 2011, Volume: 38, Issue:4

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Disease Progression; F

2011
Glioblastoma: patterns of recurrence and efficacy of salvage treatments.
    The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques, 2011, Volume: 38, Issue:4

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Disease Progression; F

2011
Immunotherapy for glioblastoma: the devil is in the details.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2011, Aug-01, Volume: 29, Issue:22

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cancer Vaccines; Chemotherapy, Adjuvant; Clinica

2011
Immunotherapy for glioblastoma: the devil is in the details.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2011, Aug-01, Volume: 29, Issue:22

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cancer Vaccines; Chemotherapy, Adjuvant; Clinica

2011
Immunotherapy for glioblastoma: the devil is in the details.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2011, Aug-01, Volume: 29, Issue:22

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cancer Vaccines; Chemotherapy, Adjuvant; Clinica

2011
YB-1 dependent virotherapy in combination with temozolomide as a multimodal therapy approach to eradicate malignant glioma.
    International journal of cancer, 2011, Sep-01, Volume: 129, Issue:5

    Topics: Adenoviridae; Animals; Antineoplastic Combined Chemotherapy Protocols; Blotting, Southern; Blotting,

2011
YB-1 dependent virotherapy in combination with temozolomide as a multimodal therapy approach to eradicate malignant glioma.
    International journal of cancer, 2011, Sep-01, Volume: 129, Issue:5

    Topics: Adenoviridae; Animals; Antineoplastic Combined Chemotherapy Protocols; Blotting, Southern; Blotting,

2011
YB-1 dependent virotherapy in combination with temozolomide as a multimodal therapy approach to eradicate malignant glioma.
    International journal of cancer, 2011, Sep-01, Volume: 129, Issue:5

    Topics: Adenoviridae; Animals; Antineoplastic Combined Chemotherapy Protocols; Blotting, Southern; Blotting,

2011
A small-molecule IAP inhibitor overcomes resistance to cytotoxic therapies in malignant gliomas in vitro and in vivo.
    Neuro-oncology, 2011, Volume: 13, Issue:8

    Topics: Animals; Antineoplastic Agents; Apoptosis; Blotting, Western; Brain Neoplasms; Cell Line, Tumor; Cel

2011
A small-molecule IAP inhibitor overcomes resistance to cytotoxic therapies in malignant gliomas in vitro and in vivo.
    Neuro-oncology, 2011, Volume: 13, Issue:8

    Topics: Animals; Antineoplastic Agents; Apoptosis; Blotting, Western; Brain Neoplasms; Cell Line, Tumor; Cel

2011
A small-molecule IAP inhibitor overcomes resistance to cytotoxic therapies in malignant gliomas in vitro and in vivo.
    Neuro-oncology, 2011, Volume: 13, Issue:8

    Topics: Animals; Antineoplastic Agents; Apoptosis; Blotting, Western; Brain Neoplasms; Cell Line, Tumor; Cel

2011
Prolonged temozolomide for treatment of glioblastoma: preliminary clinical results and prognostic value of p53 overexpression.
    Journal of neuro-oncology, 2012, Volume: 106, Issue:1

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Proliferation; Chemotherapy, A

2012
Prolonged temozolomide for treatment of glioblastoma: preliminary clinical results and prognostic value of p53 overexpression.
    Journal of neuro-oncology, 2012, Volume: 106, Issue:1

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Proliferation; Chemotherapy, A

2012
Prolonged temozolomide for treatment of glioblastoma: preliminary clinical results and prognostic value of p53 overexpression.
    Journal of neuro-oncology, 2012, Volume: 106, Issue:1

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Proliferation; Chemotherapy, A

2012
Intravenous administration of temozolomide as a useful alternative over oral treatment with temozolomide capsules in patients with gliomas.
    Journal of neuro-oncology, 2012, Volume: 106, Issue:1

    Topics: Adult; Antineoplastic Agents, Alkylating; Brain Neoplasms; Capsules; Child; Child, Preschool; Dacarb

2012
Intravenous administration of temozolomide as a useful alternative over oral treatment with temozolomide capsules in patients with gliomas.
    Journal of neuro-oncology, 2012, Volume: 106, Issue:1

    Topics: Adult; Antineoplastic Agents, Alkylating; Brain Neoplasms; Capsules; Child; Child, Preschool; Dacarb

2012
Intravenous administration of temozolomide as a useful alternative over oral treatment with temozolomide capsules in patients with gliomas.
    Journal of neuro-oncology, 2012, Volume: 106, Issue:1

    Topics: Adult; Antineoplastic Agents, Alkylating; Brain Neoplasms; Capsules; Child; Child, Preschool; Dacarb

2012
Determination of temozolomide in serum and brain tumor with micellar electrokinetic capillary chromatography.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2011, Aug-01, Volume: 879, Issue:23

    Topics: Antineoplastic Agents; Brain Chemistry; Brain Neoplasms; Chromatography, Micellar Electrokinetic Cap

2011
Determination of temozolomide in serum and brain tumor with micellar electrokinetic capillary chromatography.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2011, Aug-01, Volume: 879, Issue:23

    Topics: Antineoplastic Agents; Brain Chemistry; Brain Neoplasms; Chromatography, Micellar Electrokinetic Cap

2011
Determination of temozolomide in serum and brain tumor with micellar electrokinetic capillary chromatography.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2011, Aug-01, Volume: 879, Issue:23

    Topics: Antineoplastic Agents; Brain Chemistry; Brain Neoplasms; Chromatography, Micellar Electrokinetic Cap

2011
[Cutaneous neutrophils infiltrates. Case 4. Pseudo-tumoral cutaneous alternariosis].
    Annales de pathologie, 2011, Volume: 31, Issue:3

    Topics: Aged, 80 and over; Alternaria; Antifungal Agents; Antineoplastic Agents, Alkylating; Brain Neoplasms

2011
[Cutaneous neutrophils infiltrates. Case 4. Pseudo-tumoral cutaneous alternariosis].
    Annales de pathologie, 2011, Volume: 31, Issue:3

    Topics: Aged, 80 and over; Alternaria; Antifungal Agents; Antineoplastic Agents, Alkylating; Brain Neoplasms

2011
[Cutaneous neutrophils infiltrates. Case 4. Pseudo-tumoral cutaneous alternariosis].
    Annales de pathologie, 2011, Volume: 31, Issue:3

    Topics: Aged, 80 and over; Alternaria; Antifungal Agents; Antineoplastic Agents, Alkylating; Brain Neoplasms

2011
Immunosuppression in patients with high-grade gliomas treated with radiation and temozolomide.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2011, Aug-15, Volume: 17, Issue:16

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; CD4 Lymphocyte C

2011
Immunosuppression in patients with high-grade gliomas treated with radiation and temozolomide.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2011, Aug-15, Volume: 17, Issue:16

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; CD4 Lymphocyte C

2011
Immunosuppression in patients with high-grade gliomas treated with radiation and temozolomide.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2011, Aug-15, Volume: 17, Issue:16

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; CD4 Lymphocyte C

2011
[Problems of chemotherapy for glioma].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2011, Volume: 38, Issue:6

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; DNA; DNA Mismatch Repair; Drug Resi

2011
[Problems of chemotherapy for glioma].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2011, Volume: 38, Issue:6

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; DNA; DNA Mismatch Repair; Drug Resi

2011
[Problems of chemotherapy for glioma].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2011, Volume: 38, Issue:6

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; DNA; DNA Mismatch Repair; Drug Resi

2011
Combination of neoadjuvant chemotherapy followed by surgical resection as a new strategy for WHO grade II gliomas: a study of cognitive status and quality of life.
    Journal of neuro-oncology, 2012, Volume: 106, Issue:2

    Topics: Adult; Antineoplastic Agents; Brain Neoplasms; Chemotherapy, Adjuvant; Cognition; Dacarbazine; Femal

2012
Combination of neoadjuvant chemotherapy followed by surgical resection as a new strategy for WHO grade II gliomas: a study of cognitive status and quality of life.
    Journal of neuro-oncology, 2012, Volume: 106, Issue:2

    Topics: Adult; Antineoplastic Agents; Brain Neoplasms; Chemotherapy, Adjuvant; Cognition; Dacarbazine; Femal

2012
Combination of neoadjuvant chemotherapy followed by surgical resection as a new strategy for WHO grade II gliomas: a study of cognitive status and quality of life.
    Journal of neuro-oncology, 2012, Volume: 106, Issue:2

    Topics: Adult; Antineoplastic Agents; Brain Neoplasms; Chemotherapy, Adjuvant; Cognition; Dacarbazine; Femal

2012
MGMT promoter gene methylation in pediatric glioblastoma: analysis using MS-MLPA.
    Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 2011, Volume: 27, Issue:11

    Topics: Adolescent; Antineoplastic Agents; Brain Neoplasms; Child; Child, Preschool; Dacarbazine; Disease-Fr

2011
MGMT promoter gene methylation in pediatric glioblastoma: analysis using MS-MLPA.
    Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 2011, Volume: 27, Issue:11

    Topics: Adolescent; Antineoplastic Agents; Brain Neoplasms; Child; Child, Preschool; Dacarbazine; Disease-Fr

2011
MGMT promoter gene methylation in pediatric glioblastoma: analysis using MS-MLPA.
    Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 2011, Volume: 27, Issue:11

    Topics: Adolescent; Antineoplastic Agents; Brain Neoplasms; Child; Child, Preschool; Dacarbazine; Disease-Fr

2011
Ifosfamide, carboplatin and etoposide in recurrent malignant glioma.
    Oncology, 2011, Volume: 80, Issue:5-6

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Astrocytoma; Brain Neoplasms; Carboplat

2011
Ifosfamide, carboplatin and etoposide in recurrent malignant glioma.
    Oncology, 2011, Volume: 80, Issue:5-6

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Astrocytoma; Brain Neoplasms; Carboplat

2011
Ifosfamide, carboplatin and etoposide in recurrent malignant glioma.
    Oncology, 2011, Volume: 80, Issue:5-6

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Astrocytoma; Brain Neoplasms; Carboplat

2011
Gene expression profiles predicting the response to IFN-β and a combination of temozolomide and IFN-β in malignant gliomas.
    International journal of oncology, 2011, Volume: 39, Issue:3

    Topics: 2',5'-Oligoadenylate Synthetase; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Ce

2011
Gene expression profiles predicting the response to IFN-β and a combination of temozolomide and IFN-β in malignant gliomas.
    International journal of oncology, 2011, Volume: 39, Issue:3

    Topics: 2',5'-Oligoadenylate Synthetase; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Ce

2011
Gene expression profiles predicting the response to IFN-β and a combination of temozolomide and IFN-β in malignant gliomas.
    International journal of oncology, 2011, Volume: 39, Issue:3

    Topics: 2',5'-Oligoadenylate Synthetase; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Ce

2011
Hepatitis B virus reactivation associated with temozolomide for malignant glioma: a case report and recommendation for prophylaxis.
    International journal of clinical oncology, 2012, Volume: 17, Issue:3

    Topics: Antineoplastic Agents, Alkylating; Antiviral Agents; Astrocytoma; Brain Neoplasms; Carrier State; Ch

2012
Hepatitis B virus reactivation associated with temozolomide for malignant glioma: a case report and recommendation for prophylaxis.
    International journal of clinical oncology, 2012, Volume: 17, Issue:3

    Topics: Antineoplastic Agents, Alkylating; Antiviral Agents; Astrocytoma; Brain Neoplasms; Carrier State; Ch

2012
Hepatitis B virus reactivation associated with temozolomide for malignant glioma: a case report and recommendation for prophylaxis.
    International journal of clinical oncology, 2012, Volume: 17, Issue:3

    Topics: Antineoplastic Agents, Alkylating; Antiviral Agents; Astrocytoma; Brain Neoplasms; Carrier State; Ch

2012
[Significant regression of glioblastoma with low level of Mgmt gene expression following radiotherapy].
    Voprosy onkologii, 2011, Volume: 57, Issue:2

    Topics: Adult; Antineoplastic Agents, Alkylating; Biomarkers, Tumor; Brain Neoplasms; Chemotherapy, Adjuvant

2011
[Significant regression of glioblastoma with low level of Mgmt gene expression following radiotherapy].
    Voprosy onkologii, 2011, Volume: 57, Issue:2

    Topics: Adult; Antineoplastic Agents, Alkylating; Biomarkers, Tumor; Brain Neoplasms; Chemotherapy, Adjuvant

2011
[Significant regression of glioblastoma with low level of Mgmt gene expression following radiotherapy].
    Voprosy onkologii, 2011, Volume: 57, Issue:2

    Topics: Adult; Antineoplastic Agents, Alkylating; Biomarkers, Tumor; Brain Neoplasms; Chemotherapy, Adjuvant

2011
In regard McDonald et al., to Pattern of failure after limited margin radiotherapy and temozolomide for glioblastoma (Int J Radiat Oncol Biol Phys 2011;79:130-136).
    International journal of radiation oncology, biology, physics, 2011, Sep-01, Volume: 81, Issue:1

    Topics: Antineoplastic Agents; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease Progression;

2011
In regard McDonald et al., to Pattern of failure after limited margin radiotherapy and temozolomide for glioblastoma (Int J Radiat Oncol Biol Phys 2011;79:130-136).
    International journal of radiation oncology, biology, physics, 2011, Sep-01, Volume: 81, Issue:1

    Topics: Antineoplastic Agents; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease Progression;

2011
In regard McDonald et al., to Pattern of failure after limited margin radiotherapy and temozolomide for glioblastoma (Int J Radiat Oncol Biol Phys 2011;79:130-136).
    International journal of radiation oncology, biology, physics, 2011, Sep-01, Volume: 81, Issue:1

    Topics: Antineoplastic Agents; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease Progression;

2011
Method for novel anti-cancer drug development using tumor explants of surgical specimens.
    Journal of visualized experiments : JoVE, 2011, Jul-29, Issue:53

    Topics: Antineoplastic Agents; Brain Neoplasms; Dacarbazine; Drug Screening Assays, Antitumor; Flow Cytometr

2011
Method for novel anti-cancer drug development using tumor explants of surgical specimens.
    Journal of visualized experiments : JoVE, 2011, Jul-29, Issue:53

    Topics: Antineoplastic Agents; Brain Neoplasms; Dacarbazine; Drug Screening Assays, Antitumor; Flow Cytometr

2011
Method for novel anti-cancer drug development using tumor explants of surgical specimens.
    Journal of visualized experiments : JoVE, 2011, Jul-29, Issue:53

    Topics: Antineoplastic Agents; Brain Neoplasms; Dacarbazine; Drug Screening Assays, Antitumor; Flow Cytometr

2011
Prolonged survival when temozolomide is added to accelerated radiotherapy for glioblastoma multiforme.
    Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 2011, Volume: 187, Issue:9

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant;

2011
Prolonged survival when temozolomide is added to accelerated radiotherapy for glioblastoma multiforme.
    Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 2011, Volume: 187, Issue:9

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant;

2011
Prolonged survival when temozolomide is added to accelerated radiotherapy for glioblastoma multiforme.
    Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 2011, Volume: 187, Issue:9

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant;

2011
Temozolomide in relapsed pediatric brain tumors: 14 cases from a single center.
    Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 2012, Volume: 28, Issue:1

    Topics: Adolescent; Antineoplastic Agents, Alkylating; Brain Neoplasms; Child; Child, Preschool; Dacarbazine

2012
Temozolomide in relapsed pediatric brain tumors: 14 cases from a single center.
    Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 2012, Volume: 28, Issue:1

    Topics: Adolescent; Antineoplastic Agents, Alkylating; Brain Neoplasms; Child; Child, Preschool; Dacarbazine

2012
Temozolomide in relapsed pediatric brain tumors: 14 cases from a single center.
    Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 2012, Volume: 28, Issue:1

    Topics: Adolescent; Antineoplastic Agents, Alkylating; Brain Neoplasms; Child; Child, Preschool; Dacarbazine

2012
Early-stage progress on glioma vaccines.
    Journal of the National Cancer Institute, 2011, Sep-21, Volume: 103, Issue:18

    Topics: Antibodies, Monoclonal; Antineoplastic Agents; Brain Neoplasms; Cancer Vaccines; Clinical Trials as

2011
Early-stage progress on glioma vaccines.
    Journal of the National Cancer Institute, 2011, Sep-21, Volume: 103, Issue:18

    Topics: Antibodies, Monoclonal; Antineoplastic Agents; Brain Neoplasms; Cancer Vaccines; Clinical Trials as

2011
Early-stage progress on glioma vaccines.
    Journal of the National Cancer Institute, 2011, Sep-21, Volume: 103, Issue:18

    Topics: Antibodies, Monoclonal; Antineoplastic Agents; Brain Neoplasms; Cancer Vaccines; Clinical Trials as

2011
Adult glioblastoma multiforme survival in the temozolomide era: a population-based analysis of Surveillance, Epidemiology, and End Results registries.
    Cancer, 2012, Apr-15, Volume: 118, Issue:8

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Fem

2012
Adult glioblastoma multiforme survival in the temozolomide era: a population-based analysis of Surveillance, Epidemiology, and End Results registries.
    Cancer, 2012, Apr-15, Volume: 118, Issue:8

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Fem

2012
Adult glioblastoma multiforme survival in the temozolomide era: a population-based analysis of Surveillance, Epidemiology, and End Results registries.
    Cancer, 2012, Apr-15, Volume: 118, Issue:8

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Fem

2012
Inhibition of STAT3 reverses alkylator resistance through modulation of the AKT and β-catenin signaling pathways.
    Oncology reports, 2011, Volume: 26, Issue:5

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; beta Catenin; Brain Neoplasms; Cell Line

2011
Inhibition of STAT3 reverses alkylator resistance through modulation of the AKT and β-catenin signaling pathways.
    Oncology reports, 2011, Volume: 26, Issue:5

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; beta Catenin; Brain Neoplasms; Cell Line

2011
Inhibition of STAT3 reverses alkylator resistance through modulation of the AKT and β-catenin signaling pathways.
    Oncology reports, 2011, Volume: 26, Issue:5

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; beta Catenin; Brain Neoplasms; Cell Line

2011
Bevacizumab-induced reversible posterior leukoencephalopathy syndrome and successful retreatment in a patient with glioblastoma.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2011, Oct-01, Volume: 29, Issue:28

    Topics: Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Brai

2011
Bevacizumab-induced reversible posterior leukoencephalopathy syndrome and successful retreatment in a patient with glioblastoma.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2011, Oct-01, Volume: 29, Issue:28

    Topics: Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Brai

2011
Bevacizumab-induced reversible posterior leukoencephalopathy syndrome and successful retreatment in a patient with glioblastoma.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2011, Oct-01, Volume: 29, Issue:28

    Topics: Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Brai

2011
Communicating hydrocephalus following surgery and adjuvant radiochemotherapy for glioblastoma.
    Journal of neurosurgery, 2011, Volume: 115, Issue:6

    Topics: Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cerebrospinal Fluid Shunts; Chemoradiother

2011
Communicating hydrocephalus following surgery and adjuvant radiochemotherapy for glioblastoma.
    Journal of neurosurgery, 2011, Volume: 115, Issue:6

    Topics: Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cerebrospinal Fluid Shunts; Chemoradiother

2011
Communicating hydrocephalus following surgery and adjuvant radiochemotherapy for glioblastoma.
    Journal of neurosurgery, 2011, Volume: 115, Issue:6

    Topics: Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cerebrospinal Fluid Shunts; Chemoradiother

2011
Prognostic significance of IDH-1 and MGMT in patients with glioblastoma: one step forward, and one step back?
    Radiation oncology (London, England), 2011, Sep-13, Volume: 6

    Topics: Adult; Aged; Brain Neoplasms; Dacarbazine; DNA Methylation; Glioblastoma; Humans; Isocitrate Dehydro

2011
Prognostic significance of IDH-1 and MGMT in patients with glioblastoma: one step forward, and one step back?
    Radiation oncology (London, England), 2011, Sep-13, Volume: 6

    Topics: Adult; Aged; Brain Neoplasms; Dacarbazine; DNA Methylation; Glioblastoma; Humans; Isocitrate Dehydro

2011
Prognostic significance of IDH-1 and MGMT in patients with glioblastoma: one step forward, and one step back?
    Radiation oncology (London, England), 2011, Sep-13, Volume: 6

    Topics: Adult; Aged; Brain Neoplasms; Dacarbazine; DNA Methylation; Glioblastoma; Humans; Isocitrate Dehydro

2011
Improvement in the standard treatment for experimental glioma by fusing antibody Fc domain to endostatin.
    Journal of neurosurgery, 2011, Volume: 115, Issue:6

    Topics: Administration, Oral; Angiogenesis Inhibitors; Animals; Antineoplastic Agents, Alkylating; Antineopl

2011
Improvement in the standard treatment for experimental glioma by fusing antibody Fc domain to endostatin.
    Journal of neurosurgery, 2011, Volume: 115, Issue:6

    Topics: Administration, Oral; Angiogenesis Inhibitors; Animals; Antineoplastic Agents, Alkylating; Antineopl

2011
Improvement in the standard treatment for experimental glioma by fusing antibody Fc domain to endostatin.
    Journal of neurosurgery, 2011, Volume: 115, Issue:6

    Topics: Administration, Oral; Angiogenesis Inhibitors; Animals; Antineoplastic Agents, Alkylating; Antineopl

2011
Noscapine inhibits tumor growth in TMZ-resistant gliomas.
    Cancer letters, 2011, Dec-22, Volume: 312, Issue:2

    Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Cell Division; Dacarbazine; Drug Resistance, Neopla

2011
Noscapine inhibits tumor growth in TMZ-resistant gliomas.
    Cancer letters, 2011, Dec-22, Volume: 312, Issue:2

    Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Cell Division; Dacarbazine; Drug Resistance, Neopla

2011
Noscapine inhibits tumor growth in TMZ-resistant gliomas.
    Cancer letters, 2011, Dec-22, Volume: 312, Issue:2

    Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Cell Division; Dacarbazine; Drug Resistance, Neopla

2011
Conditional probability of survival in patients with newly diagnosed glioblastoma.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2011, Nov-01, Volume: 29, Issue:31

    Topics: Adult; Age Factors; Aged; Antineoplastic Agents; Brain Neoplasms; Chemotherapy, Adjuvant; Clinical T

2011
Conditional probability of survival in patients with newly diagnosed glioblastoma.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2011, Nov-01, Volume: 29, Issue:31

    Topics: Adult; Age Factors; Aged; Antineoplastic Agents; Brain Neoplasms; Chemotherapy, Adjuvant; Clinical T

2011
Conditional probability of survival in patients with newly diagnosed glioblastoma.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2011, Nov-01, Volume: 29, Issue:31

    Topics: Adult; Age Factors; Aged; Antineoplastic Agents; Brain Neoplasms; Chemotherapy, Adjuvant; Clinical T

2011
Protein alterations associated with temozolomide resistance in subclones of human glioblastoma cell lines.
    Journal of neuro-oncology, 2012, Volume: 107, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Apoptosis; Biomarkers, Tumor; Blotting, Western; Brain Neoplasms;

2012
Protein alterations associated with temozolomide resistance in subclones of human glioblastoma cell lines.
    Journal of neuro-oncology, 2012, Volume: 107, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Apoptosis; Biomarkers, Tumor; Blotting, Western; Brain Neoplasms;

2012
Protein alterations associated with temozolomide resistance in subclones of human glioblastoma cell lines.
    Journal of neuro-oncology, 2012, Volume: 107, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Apoptosis; Biomarkers, Tumor; Blotting, Western; Brain Neoplasms;

2012
Rechallenge with temozolomide in recurrent glioma.
    Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 2011, Volume: 32 Suppl 2

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Drug Administration Schedule; Gliom

2011
Rechallenge with temozolomide in recurrent glioma.
    Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 2011, Volume: 32 Suppl 2

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Drug Administration Schedule; Gliom

2011
Rechallenge with temozolomide in recurrent glioma.
    Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 2011, Volume: 32 Suppl 2

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Drug Administration Schedule; Gliom

2011
Low-dose fractionated radiotherapy and concomitant chemotherapy in glioblastoma multiforme with poor prognosis: a feasibility study.
    Neuro-oncology, 2012, Volume: 14, Issue:1

    Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms;

2012
Low-dose fractionated radiotherapy and concomitant chemotherapy in glioblastoma multiforme with poor prognosis: a feasibility study.
    Neuro-oncology, 2012, Volume: 14, Issue:1

    Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms;

2012
Low-dose fractionated radiotherapy and concomitant chemotherapy in glioblastoma multiforme with poor prognosis: a feasibility study.
    Neuro-oncology, 2012, Volume: 14, Issue:1

    Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms;

2012
Primary central nervous system lymphoma presenting as Parinaud syndrome.
    Canadian journal of ophthalmology. Journal canadien d'ophtalmologie, 2011, Volume: 46, Issue:5

    Topics: Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Cranial Irradiation; Dacarbazine; D

2011
Primary central nervous system lymphoma presenting as Parinaud syndrome.
    Canadian journal of ophthalmology. Journal canadien d'ophtalmologie, 2011, Volume: 46, Issue:5

    Topics: Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Cranial Irradiation; Dacarbazine; D

2011
Primary central nervous system lymphoma presenting as Parinaud syndrome.
    Canadian journal of ophthalmology. Journal canadien d'ophtalmologie, 2011, Volume: 46, Issue:5

    Topics: Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Cranial Irradiation; Dacarbazine; D

2011
Toxicity after radiochemotherapy for glioblastoma using temozolomide--a retrospective evaluation.
    Radiation oncology (London, England), 2011, Oct-21, Volume: 6

    Topics: Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Dacarbazine; Disease Pr

2011
Toxicity after radiochemotherapy for glioblastoma using temozolomide--a retrospective evaluation.
    Radiation oncology (London, England), 2011, Oct-21, Volume: 6

    Topics: Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Dacarbazine; Disease Pr

2011
Toxicity after radiochemotherapy for glioblastoma using temozolomide--a retrospective evaluation.
    Radiation oncology (London, England), 2011, Oct-21, Volume: 6

    Topics: Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Dacarbazine; Disease Pr

2011
Reactivation of hepatitis B virus after glioblastoma treatment with temozolomide--case report.
    Neurologia medico-chirurgica, 2011, Volume: 51, Issue:10

    Topics: Acute Disease; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Fatal Outcome; Gliob

2011
Reactivation of hepatitis B virus after glioblastoma treatment with temozolomide--case report.
    Neurologia medico-chirurgica, 2011, Volume: 51, Issue:10

    Topics: Acute Disease; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Fatal Outcome; Gliob

2011
Reactivation of hepatitis B virus after glioblastoma treatment with temozolomide--case report.
    Neurologia medico-chirurgica, 2011, Volume: 51, Issue:10

    Topics: Acute Disease; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Fatal Outcome; Gliob

2011
IDH mutations predict longer survival and response to temozolomide in secondary glioblastoma.
    Cancer science, 2012, Volume: 103, Issue:2

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Base Sequence; Biomarkers, Tumor; Brain Neoplasms; D

2012
IDH mutations predict longer survival and response to temozolomide in secondary glioblastoma.
    Cancer science, 2012, Volume: 103, Issue:2

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Base Sequence; Biomarkers, Tumor; Brain Neoplasms; D

2012
IDH mutations predict longer survival and response to temozolomide in secondary glioblastoma.
    Cancer science, 2012, Volume: 103, Issue:2

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Base Sequence; Biomarkers, Tumor; Brain Neoplasms; D

2012
Avastin: more questions than answers. . .
    Journal of neurosurgery, 2012, Volume: 116, Issue:2

    Topics: Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic A

2012
Avastin: more questions than answers. . .
    Journal of neurosurgery, 2012, Volume: 116, Issue:2

    Topics: Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic A

2012
Avastin: more questions than answers. . .
    Journal of neurosurgery, 2012, Volume: 116, Issue:2

    Topics: Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic A

2012
Radiochemotherapy with temozolomide for patients with glioblastoma. Prognostic factors and long-term outcome of unselected patients from a single institution.
    Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 2011, Volume: 187, Issue:11

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Biopsy; Brain Neoplasms; Chemorad

2011
Radiochemotherapy with temozolomide for patients with glioblastoma. Prognostic factors and long-term outcome of unselected patients from a single institution.
    Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 2011, Volume: 187, Issue:11

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Biopsy; Brain Neoplasms; Chemorad

2011
Radiochemotherapy with temozolomide for patients with glioblastoma. Prognostic factors and long-term outcome of unselected patients from a single institution.
    Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 2011, Volume: 187, Issue:11

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Biopsy; Brain Neoplasms; Chemorad

2011
Valproic acid sensitizes human glioma cells for temozolomide and γ-radiation.
    Journal of neuro-oncology, 2012, Volume: 107, Issue:1

    Topics: Anticonvulsants; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Proliferation; Dacarbazine

2012
Valproic acid sensitizes human glioma cells for temozolomide and γ-radiation.
    Journal of neuro-oncology, 2012, Volume: 107, Issue:1

    Topics: Anticonvulsants; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Proliferation; Dacarbazine

2012
Valproic acid sensitizes human glioma cells for temozolomide and γ-radiation.
    Journal of neuro-oncology, 2012, Volume: 107, Issue:1

    Topics: Anticonvulsants; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Proliferation; Dacarbazine

2012
Reirradiation and concomitant metronomic temozolomide: an efficient combination for local control in medulloblastoma disease?
    Journal of pediatric hematology/oncology, 2011, Volume: 33, Issue:8

    Topics: Administration, Metronomic; Adolescent; Adult; Antineoplastic Agents, Alkylating; Brain Neoplasms; C

2011
Reirradiation and concomitant metronomic temozolomide: an efficient combination for local control in medulloblastoma disease?
    Journal of pediatric hematology/oncology, 2011, Volume: 33, Issue:8

    Topics: Administration, Metronomic; Adolescent; Adult; Antineoplastic Agents, Alkylating; Brain Neoplasms; C

2011
Reirradiation and concomitant metronomic temozolomide: an efficient combination for local control in medulloblastoma disease?
    Journal of pediatric hematology/oncology, 2011, Volume: 33, Issue:8

    Topics: Administration, Metronomic; Adolescent; Adult; Antineoplastic Agents, Alkylating; Brain Neoplasms; C

2011
Glioblastoma survival in the United States before and during the temozolomide era.
    Journal of neuro-oncology, 2012, Volume: 107, Issue:2

    Topics: Adult; Age Factors; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dac

2012
Glioblastoma survival in the United States before and during the temozolomide era.
    Journal of neuro-oncology, 2012, Volume: 107, Issue:2

    Topics: Adult; Age Factors; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dac

2012
Glioblastoma survival in the United States before and during the temozolomide era.
    Journal of neuro-oncology, 2012, Volume: 107, Issue:2

    Topics: Adult; Age Factors; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dac

2012
Concurrent temozolomide and dose-escalated intensity-modulated radiation therapy in newly diagnosed glioblastoma.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2012, Jan-01, Volume: 18, Issue:1

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Dacarbazine; Dos

2012
Concurrent temozolomide and dose-escalated intensity-modulated radiation therapy in newly diagnosed glioblastoma.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2012, Jan-01, Volume: 18, Issue:1

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Dacarbazine; Dos

2012
Concurrent temozolomide and dose-escalated intensity-modulated radiation therapy in newly diagnosed glioblastoma.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2012, Jan-01, Volume: 18, Issue:1

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Dacarbazine; Dos

2012
Downregulation of miR-221/222 sensitizes glioma cells to temozolomide by regulating apoptosis independently of p53 status.
    Oncology reports, 2012, Volume: 27, Issue:3

    Topics: Apoptosis; Apoptosis Regulatory Proteins; Apoptotic Protease-Activating Factor 1; bcl-2-Associated X

2012
Downregulation of miR-221/222 sensitizes glioma cells to temozolomide by regulating apoptosis independently of p53 status.
    Oncology reports, 2012, Volume: 27, Issue:3

    Topics: Apoptosis; Apoptosis Regulatory Proteins; Apoptotic Protease-Activating Factor 1; bcl-2-Associated X

2012
Downregulation of miR-221/222 sensitizes glioma cells to temozolomide by regulating apoptosis independently of p53 status.
    Oncology reports, 2012, Volume: 27, Issue:3

    Topics: Apoptosis; Apoptosis Regulatory Proteins; Apoptotic Protease-Activating Factor 1; bcl-2-Associated X

2012
Resveratrol enhances the therapeutic effect of temozolomide against malignant glioma in vitro and in vivo by inhibiting autophagy.
    Free radical biology & medicine, 2012, Jan-15, Volume: 52, Issue:2

    Topics: Animals; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Apoptosi

2012
Resveratrol enhances the therapeutic effect of temozolomide against malignant glioma in vitro and in vivo by inhibiting autophagy.
    Free radical biology & medicine, 2012, Jan-15, Volume: 52, Issue:2

    Topics: Animals; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Apoptosi

2012
Resveratrol enhances the therapeutic effect of temozolomide against malignant glioma in vitro and in vivo by inhibiting autophagy.
    Free radical biology & medicine, 2012, Jan-15, Volume: 52, Issue:2

    Topics: Animals; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Apoptosi

2012
Higher topoisomerase 2 alpha gene transcript levels predict better prognosis in GBM patients receiving temozolomide chemotherapy: identification of temozolomide as a TOP2A inhibitor.
    Journal of neuro-oncology, 2012, Volume: 107, Issue:2

    Topics: Antigens, Neoplasm; Antineoplastic Agents; Brain Neoplasms; Camptothecin; Cell Line, Tumor; Cell Pro

2012
Higher topoisomerase 2 alpha gene transcript levels predict better prognosis in GBM patients receiving temozolomide chemotherapy: identification of temozolomide as a TOP2A inhibitor.
    Journal of neuro-oncology, 2012, Volume: 107, Issue:2

    Topics: Antigens, Neoplasm; Antineoplastic Agents; Brain Neoplasms; Camptothecin; Cell Line, Tumor; Cell Pro

2012
Higher topoisomerase 2 alpha gene transcript levels predict better prognosis in GBM patients receiving temozolomide chemotherapy: identification of temozolomide as a TOP2A inhibitor.
    Journal of neuro-oncology, 2012, Volume: 107, Issue:2

    Topics: Antigens, Neoplasm; Antineoplastic Agents; Brain Neoplasms; Camptothecin; Cell Line, Tumor; Cell Pro

2012
Patterns of imaging failures in glioblastoma patients treated with chemoradiation: a retrospective study.
    Medical oncology (Northwood, London, England), 2012, Volume: 29, Issue:3

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Brain Neoplasms; Chemoradiotherap

2012
Patterns of imaging failures in glioblastoma patients treated with chemoradiation: a retrospective study.
    Medical oncology (Northwood, London, England), 2012, Volume: 29, Issue:3

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Brain Neoplasms; Chemoradiotherap

2012
Patterns of imaging failures in glioblastoma patients treated with chemoradiation: a retrospective study.
    Medical oncology (Northwood, London, England), 2012, Volume: 29, Issue:3

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Brain Neoplasms; Chemoradiotherap

2012
Prolonged administration of temozolomide in adult patients with anaplastic glioma.
    Anticancer research, 2011, Volume: 31, Issue:11

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Carcinoma; Dacarbazine; Disease Pro

2011
Prolonged administration of temozolomide in adult patients with anaplastic glioma.
    Anticancer research, 2011, Volume: 31, Issue:11

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Carcinoma; Dacarbazine; Disease Pro

2011
Prolonged administration of temozolomide in adult patients with anaplastic glioma.
    Anticancer research, 2011, Volume: 31, Issue:11

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Carcinoma; Dacarbazine; Disease Pro

2011
Prognostic impact of hemoglobin level and other factors in patients with high-grade gliomas treated with postoperative radiochemotherapy and sequential chemotherapy based on temozolomide: a 10-year experience at a single institution.
    Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 2011, Volume: 187, Issue:12

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neoplasms; Chemoradiotherapy, Adj

2011
Prognostic impact of hemoglobin level and other factors in patients with high-grade gliomas treated with postoperative radiochemotherapy and sequential chemotherapy based on temozolomide: a 10-year experience at a single institution.
    Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 2011, Volume: 187, Issue:12

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neoplasms; Chemoradiotherapy, Adj

2011
Prognostic impact of hemoglobin level and other factors in patients with high-grade gliomas treated with postoperative radiochemotherapy and sequential chemotherapy based on temozolomide: a 10-year experience at a single institution.
    Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 2011, Volume: 187, Issue:12

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neoplasms; Chemoradiotherapy, Adj

2011
Temozolomide induced liver injury.
    Acta neurologica Belgica, 2011, Volume: 111, Issue:3

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemical and Drug Induced Liver Injury; Chemorad

2011
Temozolomide induced liver injury.
    Acta neurologica Belgica, 2011, Volume: 111, Issue:3

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemical and Drug Induced Liver Injury; Chemorad

2011
Temozolomide induced liver injury.
    Acta neurologica Belgica, 2011, Volume: 111, Issue:3

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemical and Drug Induced Liver Injury; Chemorad

2011
Early post-treatment pseudo-progression amongst glioblastoma multiforme patients treated with radiotherapy and temozolomide: a retrospective analysis.
    Journal of medical imaging and radiation oncology, 2011, Volume: 55, Issue:6

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Dacarbazine; Fem

2011
Early post-treatment pseudo-progression amongst glioblastoma multiforme patients treated with radiotherapy and temozolomide: a retrospective analysis.
    Journal of medical imaging and radiation oncology, 2011, Volume: 55, Issue:6

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Dacarbazine; Fem

2011
Early post-treatment pseudo-progression amongst glioblastoma multiforme patients treated with radiotherapy and temozolomide: a retrospective analysis.
    Journal of medical imaging and radiation oncology, 2011, Volume: 55, Issue:6

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Dacarbazine; Fem

2011
Inhibition of Aurora kinases enhances chemosensitivity to temozolomide and causes radiosensitization in glioblastoma cells.
    Journal of cancer research and clinical oncology, 2012, Volume: 138, Issue:3

    Topics: Antineoplastic Agents, Alkylating; Apoptosis; Aurora Kinase B; Aurora Kinases; Benzamides; Blotting,

2012
Inhibition of Aurora kinases enhances chemosensitivity to temozolomide and causes radiosensitization in glioblastoma cells.
    Journal of cancer research and clinical oncology, 2012, Volume: 138, Issue:3

    Topics: Antineoplastic Agents, Alkylating; Apoptosis; Aurora Kinase B; Aurora Kinases; Benzamides; Blotting,

2012
Inhibition of Aurora kinases enhances chemosensitivity to temozolomide and causes radiosensitization in glioblastoma cells.
    Journal of cancer research and clinical oncology, 2012, Volume: 138, Issue:3

    Topics: Antineoplastic Agents, Alkylating; Apoptosis; Aurora Kinase B; Aurora Kinases; Benzamides; Blotting,

2012
[Efficacy and safety of 3-dimensional conformal radiotherapy combined with temozolomide for glioma].
    Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences, 2011, Volume: 36, Issue:11

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbaz

2011
[Efficacy and safety of 3-dimensional conformal radiotherapy combined with temozolomide for glioma].
    Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences, 2011, Volume: 36, Issue:11

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbaz

2011
[Efficacy and safety of 3-dimensional conformal radiotherapy combined with temozolomide for glioma].
    Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences, 2011, Volume: 36, Issue:11

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbaz

2011
Oncolytic virus-mediated manipulation of DNA damage responses: synergy with chemotherapy in killing glioblastoma stem cells.
    Journal of the National Cancer Institute, 2012, Jan-04, Volume: 104, Issue:1

    Topics: Animals; Antineoplastic Agents, Alkylating; Ataxia Telangiectasia Mutated Proteins; Brain Neoplasms;

2012
Oncolytic virus-mediated manipulation of DNA damage responses: synergy with chemotherapy in killing glioblastoma stem cells.
    Journal of the National Cancer Institute, 2012, Jan-04, Volume: 104, Issue:1

    Topics: Animals; Antineoplastic Agents, Alkylating; Ataxia Telangiectasia Mutated Proteins; Brain Neoplasms;

2012
Oncolytic virus-mediated manipulation of DNA damage responses: synergy with chemotherapy in killing glioblastoma stem cells.
    Journal of the National Cancer Institute, 2012, Jan-04, Volume: 104, Issue:1

    Topics: Animals; Antineoplastic Agents, Alkylating; Ataxia Telangiectasia Mutated Proteins; Brain Neoplasms;

2012
Neuronal markers are expressed in human gliomas and NSE knockdown sensitizes glioblastoma cells to radiotherapy and temozolomide.
    BMC cancer, 2011, Dec-20, Volume: 11

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Biomarkers, Tumor; Biopsy; Blotting, Western; Brain

2011
Neuronal markers are expressed in human gliomas and NSE knockdown sensitizes glioblastoma cells to radiotherapy and temozolomide.
    BMC cancer, 2011, Dec-20, Volume: 11

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Biomarkers, Tumor; Biopsy; Blotting, Western; Brain

2011
Neuronal markers are expressed in human gliomas and NSE knockdown sensitizes glioblastoma cells to radiotherapy and temozolomide.
    BMC cancer, 2011, Dec-20, Volume: 11

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Biomarkers, Tumor; Biopsy; Blotting, Western; Brain

2011
Retrospective study of patients with brain metastases from melanoma receiving concurrent whole-brain radiation and temozolomide.
    Anticancer research, 2011, Volume: 31, Issue:12

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Brain Neoplasms; Combined Modality Therapy; D

2011
Retrospective study of patients with brain metastases from melanoma receiving concurrent whole-brain radiation and temozolomide.
    Anticancer research, 2011, Volume: 31, Issue:12

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Brain Neoplasms; Combined Modality Therapy; D

2011
Retrospective study of patients with brain metastases from melanoma receiving concurrent whole-brain radiation and temozolomide.
    Anticancer research, 2011, Volume: 31, Issue:12

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Brain Neoplasms; Combined Modality Therapy; D

2011
Complete remission after bevacizumab plus temozolomide in a patient with recurrent glioblastoma multiforme.
    Acta oncologica (Stockholm, Sweden), 2012, Volume: 51, Issue:4

    Topics: Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Brai

2012
Complete remission after bevacizumab plus temozolomide in a patient with recurrent glioblastoma multiforme.
    Acta oncologica (Stockholm, Sweden), 2012, Volume: 51, Issue:4

    Topics: Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Brai

2012
Complete remission after bevacizumab plus temozolomide in a patient with recurrent glioblastoma multiforme.
    Acta oncologica (Stockholm, Sweden), 2012, Volume: 51, Issue:4

    Topics: Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Brai

2012
Volumetric and MGMT parameters in glioblastoma patients: survival analysis.
    BMC cancer, 2012, Jan-03, Volume: 12

    Topics: Adult; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Dacarbazine; Disease-F

2012
Volumetric and MGMT parameters in glioblastoma patients: survival analysis.
    BMC cancer, 2012, Jan-03, Volume: 12

    Topics: Adult; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Dacarbazine; Disease-F

2012
Volumetric and MGMT parameters in glioblastoma patients: survival analysis.
    BMC cancer, 2012, Jan-03, Volume: 12

    Topics: Adult; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Dacarbazine; Disease-F

2012
Radiotherapy with and without temozolomide in elderly patients with glioblastoma.
    Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 2012, Volume: 188, Issue:2

    Topics: Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Daca

2012
Radiotherapy with and without temozolomide in elderly patients with glioblastoma.
    Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 2012, Volume: 188, Issue:2

    Topics: Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Daca

2012
Radiotherapy with and without temozolomide in elderly patients with glioblastoma.
    Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 2012, Volume: 188, Issue:2

    Topics: Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Daca

2012
[Brain metastasis in breast cancer].
    Voprosy onkologii, 2011, Volume: 57, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Antibodies, Monoclonal; Antineoplastic Agents, Alkylating; Antineopl

2011
[Brain metastasis in breast cancer].
    Voprosy onkologii, 2011, Volume: 57, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Antibodies, Monoclonal; Antineoplastic Agents, Alkylating; Antineopl

2011
[Brain metastasis in breast cancer].
    Voprosy onkologii, 2011, Volume: 57, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Antibodies, Monoclonal; Antineoplastic Agents, Alkylating; Antineopl

2011
Patterns of care and survival for patients with glioblastoma multiforme diagnosed during 2006.
    Neuro-oncology, 2012, Volume: 14, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Ad

2012
Patterns of care and survival for patients with glioblastoma multiforme diagnosed during 2006.
    Neuro-oncology, 2012, Volume: 14, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Ad

2012
Patterns of care and survival for patients with glioblastoma multiforme diagnosed during 2006.
    Neuro-oncology, 2012, Volume: 14, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Ad

2012
Temozolomide for pediatric high-grade gliomas.
    Current neurology and neuroscience reports, 2012, Volume: 12, Issue:2

    Topics: Adolescent; Antineoplastic Agents, Alkylating; Brain Neoplasms; Child; Child, Preschool; Dacarbazine

2012
Temozolomide for pediatric high-grade gliomas.
    Current neurology and neuroscience reports, 2012, Volume: 12, Issue:2

    Topics: Adolescent; Antineoplastic Agents, Alkylating; Brain Neoplasms; Child; Child, Preschool; Dacarbazine

2012
Temozolomide for pediatric high-grade gliomas.
    Current neurology and neuroscience reports, 2012, Volume: 12, Issue:2

    Topics: Adolescent; Antineoplastic Agents, Alkylating; Brain Neoplasms; Child; Child, Preschool; Dacarbazine

2012
Presence of an oligodendroglioma-like component in newly diagnosed glioblastoma identifies a pathogenetically heterogeneous subgroup and lacks prognostic value: central pathology review of the EORTC_26981/NCIC_CE.3 trial.
    Acta neuropathologica, 2012, Volume: 123, Issue:6

    Topics: Adolescent; Adult; Aged; Brain Neoplasms; Chemoradiotherapy; Clinical Trials, Phase III as Topic; Da

2012
Presence of an oligodendroglioma-like component in newly diagnosed glioblastoma identifies a pathogenetically heterogeneous subgroup and lacks prognostic value: central pathology review of the EORTC_26981/NCIC_CE.3 trial.
    Acta neuropathologica, 2012, Volume: 123, Issue:6

    Topics: Adolescent; Adult; Aged; Brain Neoplasms; Chemoradiotherapy; Clinical Trials, Phase III as Topic; Da

2012
Presence of an oligodendroglioma-like component in newly diagnosed glioblastoma identifies a pathogenetically heterogeneous subgroup and lacks prognostic value: central pathology review of the EORTC_26981/NCIC_CE.3 trial.
    Acta neuropathologica, 2012, Volume: 123, Issue:6

    Topics: Adolescent; Adult; Aged; Brain Neoplasms; Chemoradiotherapy; Clinical Trials, Phase III as Topic; Da

2012
[Retrospective analysis of 24 recurrent glioblastoma after chemoradiation and treated with nitrosoureas or irinotecan and bevacizumab].
    Bulletin du cancer, 2012, Feb-01, Volume: 99, Issue:2

    Topics: Adult; Aged; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Che

2012
[Retrospective analysis of 24 recurrent glioblastoma after chemoradiation and treated with nitrosoureas or irinotecan and bevacizumab].
    Bulletin du cancer, 2012, Feb-01, Volume: 99, Issue:2

    Topics: Adult; Aged; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Che

2012
[Retrospective analysis of 24 recurrent glioblastoma after chemoradiation and treated with nitrosoureas or irinotecan and bevacizumab].
    Bulletin du cancer, 2012, Feb-01, Volume: 99, Issue:2

    Topics: Adult; Aged; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Che

2012
Prospective cohort study of radiotherapy with concomitant and adjuvant temozolomide chemotherapy for glioblastoma patients with no or minimal residual enhancing tumor load after surgery.
    Journal of neuro-oncology, 2012, Volume: 108, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cohort Studies;

2012
Prospective cohort study of radiotherapy with concomitant and adjuvant temozolomide chemotherapy for glioblastoma patients with no or minimal residual enhancing tumor load after surgery.
    Journal of neuro-oncology, 2012, Volume: 108, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cohort Studies;

2012
Prospective cohort study of radiotherapy with concomitant and adjuvant temozolomide chemotherapy for glioblastoma patients with no or minimal residual enhancing tumor load after surgery.
    Journal of neuro-oncology, 2012, Volume: 108, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cohort Studies;

2012
[Protracted low-dose temozolomide combined with concomitant whole brain radiotherapy for brain metastases from non-small cell lung cancer].
    Zhonghua zhong liu za zhi [Chinese journal of oncology], 2011, Volume: 33, Issue:10

    Topics: Adult; Aged; Agranulocytosis; Antineoplastic Agents, Alkylating; Brain Neoplasms; Carcinoma, Non-Sma

2011
[Protracted low-dose temozolomide combined with concomitant whole brain radiotherapy for brain metastases from non-small cell lung cancer].
    Zhonghua zhong liu za zhi [Chinese journal of oncology], 2011, Volume: 33, Issue:10

    Topics: Adult; Aged; Agranulocytosis; Antineoplastic Agents, Alkylating; Brain Neoplasms; Carcinoma, Non-Sma

2011
[Protracted low-dose temozolomide combined with concomitant whole brain radiotherapy for brain metastases from non-small cell lung cancer].
    Zhonghua zhong liu za zhi [Chinese journal of oncology], 2011, Volume: 33, Issue:10

    Topics: Adult; Aged; Agranulocytosis; Antineoplastic Agents, Alkylating; Brain Neoplasms; Carcinoma, Non-Sma

2011
Different involvement of autophagy in human malignant glioma cell lines undergoing irradiation and temozolomide combined treatments.
    Journal of cellular biochemistry, 2012, Volume: 113, Issue:7

    Topics: Apoptosis Regulatory Proteins; Autophagy; Autophagy-Related Protein 5; Beclin-1; Brain Neoplasms; Ce

2012
Different involvement of autophagy in human malignant glioma cell lines undergoing irradiation and temozolomide combined treatments.
    Journal of cellular biochemistry, 2012, Volume: 113, Issue:7

    Topics: Apoptosis Regulatory Proteins; Autophagy; Autophagy-Related Protein 5; Beclin-1; Brain Neoplasms; Ce

2012
Different involvement of autophagy in human malignant glioma cell lines undergoing irradiation and temozolomide combined treatments.
    Journal of cellular biochemistry, 2012, Volume: 113, Issue:7

    Topics: Apoptosis Regulatory Proteins; Autophagy; Autophagy-Related Protein 5; Beclin-1; Brain Neoplasms; Ce

2012
Induction of brain tumor stem cell apoptosis by FTY720: a potential therapeutic agent for glioblastoma.
    Neuro-oncology, 2012, Volume: 14, Issue:4

    Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Apoptosis

2012
Induction of brain tumor stem cell apoptosis by FTY720: a potential therapeutic agent for glioblastoma.
    Neuro-oncology, 2012, Volume: 14, Issue:4

    Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Apoptosis

2012
Induction of brain tumor stem cell apoptosis by FTY720: a potential therapeutic agent for glioblastoma.
    Neuro-oncology, 2012, Volume: 14, Issue:4

    Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Apoptosis

2012
O(6) -methylguanine-DNA methyltransferase (MGMT) promoter methylation and low MGMT-encoded protein expression as prognostic markers in glioblastoma patients treated with biodegradable carmustine wafer implants after initial surgery followed by radiotherap
    Cancer, 2012, Sep-15, Volume: 118, Issue:18

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Biomarkers, Tumor; Brain Neoplasms; Carmustine; Chem

2012
O(6) -methylguanine-DNA methyltransferase (MGMT) promoter methylation and low MGMT-encoded protein expression as prognostic markers in glioblastoma patients treated with biodegradable carmustine wafer implants after initial surgery followed by radiotherap
    Cancer, 2012, Sep-15, Volume: 118, Issue:18

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Biomarkers, Tumor; Brain Neoplasms; Carmustine; Chem

2012
O(6) -methylguanine-DNA methyltransferase (MGMT) promoter methylation and low MGMT-encoded protein expression as prognostic markers in glioblastoma patients treated with biodegradable carmustine wafer implants after initial surgery followed by radiotherap
    Cancer, 2012, Sep-15, Volume: 118, Issue:18

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Biomarkers, Tumor; Brain Neoplasms; Carmustine; Chem

2012
Cotard's syndrome with glioblastoma multiforme.
    Palliative & supportive care, 2012, Volume: 10, Issue:2

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Combined Modality Therapy; Co

2012
Cotard's syndrome with glioblastoma multiforme.
    Palliative & supportive care, 2012, Volume: 10, Issue:2

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Combined Modality Therapy; Co

2012
Cotard's syndrome with glioblastoma multiforme.
    Palliative & supportive care, 2012, Volume: 10, Issue:2

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Combined Modality Therapy; Co

2012
Glioblastoma: clinical characteristics, prognostic factors and survival in 492 patients.
    Clinical neurology and neurosurgery, 2012, Volume: 114, Issue:7

    Topics: Adult; Age Factors; Aged; Aged, 80 and over; Analysis of Variance; Antineoplastic Agents, Alkylating

2012
Glioblastoma: clinical characteristics, prognostic factors and survival in 492 patients.
    Clinical neurology and neurosurgery, 2012, Volume: 114, Issue:7

    Topics: Adult; Age Factors; Aged; Aged, 80 and over; Analysis of Variance; Antineoplastic Agents, Alkylating

2012
Glioblastoma: clinical characteristics, prognostic factors and survival in 492 patients.
    Clinical neurology and neurosurgery, 2012, Volume: 114, Issue:7

    Topics: Adult; Age Factors; Aged; Aged, 80 and over; Analysis of Variance; Antineoplastic Agents, Alkylating

2012
Extended adjuvant temozolomide for treatment of newly diagnosed glioblastoma multiforme.
    Journal of neuro-oncology, 2012, Volume: 108, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Ad

2012
Extended adjuvant temozolomide for treatment of newly diagnosed glioblastoma multiforme.
    Journal of neuro-oncology, 2012, Volume: 108, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Ad

2012
Extended adjuvant temozolomide for treatment of newly diagnosed glioblastoma multiforme.
    Journal of neuro-oncology, 2012, Volume: 108, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Ad

2012
The effects of temozolomide delivered by prolonged intracerebral microinfusion against the rat brainstem GBM allograft model.
    Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 2012, Volume: 28, Issue:5

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Brain Stem; Cell Line, Tumor; Dacarbazi

2012
The effects of temozolomide delivered by prolonged intracerebral microinfusion against the rat brainstem GBM allograft model.
    Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 2012, Volume: 28, Issue:5

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Brain Stem; Cell Line, Tumor; Dacarbazi

2012
The effects of temozolomide delivered by prolonged intracerebral microinfusion against the rat brainstem GBM allograft model.
    Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 2012, Volume: 28, Issue:5

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Brain Stem; Cell Line, Tumor; Dacarbazi

2012
Blood glutamate scavengers prolong the survival of rats and mice with brain-implanted gliomas.
    Investigational new drugs, 2012, Volume: 30, Issue:6

    Topics: Animals; Antineoplastic Agents, Alkylating; Aspartate Aminotransferases; Brain; Brain Neoplasms; Cel

2012
Blood glutamate scavengers prolong the survival of rats and mice with brain-implanted gliomas.
    Investigational new drugs, 2012, Volume: 30, Issue:6

    Topics: Animals; Antineoplastic Agents, Alkylating; Aspartate Aminotransferases; Brain; Brain Neoplasms; Cel

2012
Blood glutamate scavengers prolong the survival of rats and mice with brain-implanted gliomas.
    Investigational new drugs, 2012, Volume: 30, Issue:6

    Topics: Animals; Antineoplastic Agents, Alkylating; Aspartate Aminotransferases; Brain; Brain Neoplasms; Cel

2012
Blood glutamate scavengers prolong the survival of rats and mice with brain-implanted gliomas.
    Investigational new drugs, 2012, Volume: 30, Issue:6

    Topics: Animals; Antineoplastic Agents, Alkylating; Aspartate Aminotransferases; Brain; Brain Neoplasms; Cel

2012
Blood glutamate scavengers prolong the survival of rats and mice with brain-implanted gliomas.
    Investigational new drugs, 2012, Volume: 30, Issue:6

    Topics: Animals; Antineoplastic Agents, Alkylating; Aspartate Aminotransferases; Brain; Brain Neoplasms; Cel

2012
Blood glutamate scavengers prolong the survival of rats and mice with brain-implanted gliomas.
    Investigational new drugs, 2012, Volume: 30, Issue:6

    Topics: Animals; Antineoplastic Agents, Alkylating; Aspartate Aminotransferases; Brain; Brain Neoplasms; Cel

2012
Blood glutamate scavengers prolong the survival of rats and mice with brain-implanted gliomas.
    Investigational new drugs, 2012, Volume: 30, Issue:6

    Topics: Animals; Antineoplastic Agents, Alkylating; Aspartate Aminotransferases; Brain; Brain Neoplasms; Cel

2012
Blood glutamate scavengers prolong the survival of rats and mice with brain-implanted gliomas.
    Investigational new drugs, 2012, Volume: 30, Issue:6

    Topics: Animals; Antineoplastic Agents, Alkylating; Aspartate Aminotransferases; Brain; Brain Neoplasms; Cel

2012
Blood glutamate scavengers prolong the survival of rats and mice with brain-implanted gliomas.
    Investigational new drugs, 2012, Volume: 30, Issue:6

    Topics: Animals; Antineoplastic Agents, Alkylating; Aspartate Aminotransferases; Brain; Brain Neoplasms; Cel

2012
Blood glutamate scavengers prolong the survival of rats and mice with brain-implanted gliomas.
    Investigational new drugs, 2012, Volume: 30, Issue:6

    Topics: Animals; Antineoplastic Agents, Alkylating; Aspartate Aminotransferases; Brain; Brain Neoplasms; Cel

2012
Blood glutamate scavengers prolong the survival of rats and mice with brain-implanted gliomas.
    Investigational new drugs, 2012, Volume: 30, Issue:6

    Topics: Animals; Antineoplastic Agents, Alkylating; Aspartate Aminotransferases; Brain; Brain Neoplasms; Cel

2012
Blood glutamate scavengers prolong the survival of rats and mice with brain-implanted gliomas.
    Investigational new drugs, 2012, Volume: 30, Issue:6

    Topics: Animals; Antineoplastic Agents, Alkylating; Aspartate Aminotransferases; Brain; Brain Neoplasms; Cel

2012
Blood glutamate scavengers prolong the survival of rats and mice with brain-implanted gliomas.
    Investigational new drugs, 2012, Volume: 30, Issue:6

    Topics: Animals; Antineoplastic Agents, Alkylating; Aspartate Aminotransferases; Brain; Brain Neoplasms; Cel

2012
Blood glutamate scavengers prolong the survival of rats and mice with brain-implanted gliomas.
    Investigational new drugs, 2012, Volume: 30, Issue:6

    Topics: Animals; Antineoplastic Agents, Alkylating; Aspartate Aminotransferases; Brain; Brain Neoplasms; Cel

2012
Blood glutamate scavengers prolong the survival of rats and mice with brain-implanted gliomas.
    Investigational new drugs, 2012, Volume: 30, Issue:6

    Topics: Animals; Antineoplastic Agents, Alkylating; Aspartate Aminotransferases; Brain; Brain Neoplasms; Cel

2012
Blood glutamate scavengers prolong the survival of rats and mice with brain-implanted gliomas.
    Investigational new drugs, 2012, Volume: 30, Issue:6

    Topics: Animals; Antineoplastic Agents, Alkylating; Aspartate Aminotransferases; Brain; Brain Neoplasms; Cel

2012
Blood glutamate scavengers prolong the survival of rats and mice with brain-implanted gliomas.
    Investigational new drugs, 2012, Volume: 30, Issue:6

    Topics: Animals; Antineoplastic Agents, Alkylating; Aspartate Aminotransferases; Brain; Brain Neoplasms; Cel

2012
Blood glutamate scavengers prolong the survival of rats and mice with brain-implanted gliomas.
    Investigational new drugs, 2012, Volume: 30, Issue:6

    Topics: Animals; Antineoplastic Agents, Alkylating; Aspartate Aminotransferases; Brain; Brain Neoplasms; Cel

2012
Blood glutamate scavengers prolong the survival of rats and mice with brain-implanted gliomas.
    Investigational new drugs, 2012, Volume: 30, Issue:6

    Topics: Animals; Antineoplastic Agents, Alkylating; Aspartate Aminotransferases; Brain; Brain Neoplasms; Cel

2012
Blood glutamate scavengers prolong the survival of rats and mice with brain-implanted gliomas.
    Investigational new drugs, 2012, Volume: 30, Issue:6

    Topics: Animals; Antineoplastic Agents, Alkylating; Aspartate Aminotransferases; Brain; Brain Neoplasms; Cel

2012
Blood glutamate scavengers prolong the survival of rats and mice with brain-implanted gliomas.
    Investigational new drugs, 2012, Volume: 30, Issue:6

    Topics: Animals; Antineoplastic Agents, Alkylating; Aspartate Aminotransferases; Brain; Brain Neoplasms; Cel

2012
Blood glutamate scavengers prolong the survival of rats and mice with brain-implanted gliomas.
    Investigational new drugs, 2012, Volume: 30, Issue:6

    Topics: Animals; Antineoplastic Agents, Alkylating; Aspartate Aminotransferases; Brain; Brain Neoplasms; Cel

2012
Blood glutamate scavengers prolong the survival of rats and mice with brain-implanted gliomas.
    Investigational new drugs, 2012, Volume: 30, Issue:6

    Topics: Animals; Antineoplastic Agents, Alkylating; Aspartate Aminotransferases; Brain; Brain Neoplasms; Cel

2012
Blood glutamate scavengers prolong the survival of rats and mice with brain-implanted gliomas.
    Investigational new drugs, 2012, Volume: 30, Issue:6

    Topics: Animals; Antineoplastic Agents, Alkylating; Aspartate Aminotransferases; Brain; Brain Neoplasms; Cel

2012
Blood glutamate scavengers prolong the survival of rats and mice with brain-implanted gliomas.
    Investigational new drugs, 2012, Volume: 30, Issue:6

    Topics: Animals; Antineoplastic Agents, Alkylating; Aspartate Aminotransferases; Brain; Brain Neoplasms; Cel

2012
Blood glutamate scavengers prolong the survival of rats and mice with brain-implanted gliomas.
    Investigational new drugs, 2012, Volume: 30, Issue:6

    Topics: Animals; Antineoplastic Agents, Alkylating; Aspartate Aminotransferases; Brain; Brain Neoplasms; Cel

2012
Blood glutamate scavengers prolong the survival of rats and mice with brain-implanted gliomas.
    Investigational new drugs, 2012, Volume: 30, Issue:6

    Topics: Animals; Antineoplastic Agents, Alkylating; Aspartate Aminotransferases; Brain; Brain Neoplasms; Cel

2012
Blood glutamate scavengers prolong the survival of rats and mice with brain-implanted gliomas.
    Investigational new drugs, 2012, Volume: 30, Issue:6

    Topics: Animals; Antineoplastic Agents, Alkylating; Aspartate Aminotransferases; Brain; Brain Neoplasms; Cel

2012
Blood glutamate scavengers prolong the survival of rats and mice with brain-implanted gliomas.
    Investigational new drugs, 2012, Volume: 30, Issue:6

    Topics: Animals; Antineoplastic Agents, Alkylating; Aspartate Aminotransferases; Brain; Brain Neoplasms; Cel

2012
Blood glutamate scavengers prolong the survival of rats and mice with brain-implanted gliomas.
    Investigational new drugs, 2012, Volume: 30, Issue:6

    Topics: Animals; Antineoplastic Agents, Alkylating; Aspartate Aminotransferases; Brain; Brain Neoplasms; Cel

2012
Blood glutamate scavengers prolong the survival of rats and mice with brain-implanted gliomas.
    Investigational new drugs, 2012, Volume: 30, Issue:6

    Topics: Animals; Antineoplastic Agents, Alkylating; Aspartate Aminotransferases; Brain; Brain Neoplasms; Cel

2012
Blood glutamate scavengers prolong the survival of rats and mice with brain-implanted gliomas.
    Investigational new drugs, 2012, Volume: 30, Issue:6

    Topics: Animals; Antineoplastic Agents, Alkylating; Aspartate Aminotransferases; Brain; Brain Neoplasms; Cel

2012
Blood glutamate scavengers prolong the survival of rats and mice with brain-implanted gliomas.
    Investigational new drugs, 2012, Volume: 30, Issue:6

    Topics: Animals; Antineoplastic Agents, Alkylating; Aspartate Aminotransferases; Brain; Brain Neoplasms; Cel

2012
Blood glutamate scavengers prolong the survival of rats and mice with brain-implanted gliomas.
    Investigational new drugs, 2012, Volume: 30, Issue:6

    Topics: Animals; Antineoplastic Agents, Alkylating; Aspartate Aminotransferases; Brain; Brain Neoplasms; Cel

2012
Blood glutamate scavengers prolong the survival of rats and mice with brain-implanted gliomas.
    Investigational new drugs, 2012, Volume: 30, Issue:6

    Topics: Animals; Antineoplastic Agents, Alkylating; Aspartate Aminotransferases; Brain; Brain Neoplasms; Cel

2012
Blood glutamate scavengers prolong the survival of rats and mice with brain-implanted gliomas.
    Investigational new drugs, 2012, Volume: 30, Issue:6

    Topics: Animals; Antineoplastic Agents, Alkylating; Aspartate Aminotransferases; Brain; Brain Neoplasms; Cel

2012
Blood glutamate scavengers prolong the survival of rats and mice with brain-implanted gliomas.
    Investigational new drugs, 2012, Volume: 30, Issue:6

    Topics: Animals; Antineoplastic Agents, Alkylating; Aspartate Aminotransferases; Brain; Brain Neoplasms; Cel

2012
Blood glutamate scavengers prolong the survival of rats and mice with brain-implanted gliomas.
    Investigational new drugs, 2012, Volume: 30, Issue:6

    Topics: Animals; Antineoplastic Agents, Alkylating; Aspartate Aminotransferases; Brain; Brain Neoplasms; Cel

2012
Blood glutamate scavengers prolong the survival of rats and mice with brain-implanted gliomas.
    Investigational new drugs, 2012, Volume: 30, Issue:6

    Topics: Animals; Antineoplastic Agents, Alkylating; Aspartate Aminotransferases; Brain; Brain Neoplasms; Cel

2012
Blood glutamate scavengers prolong the survival of rats and mice with brain-implanted gliomas.
    Investigational new drugs, 2012, Volume: 30, Issue:6

    Topics: Animals; Antineoplastic Agents, Alkylating; Aspartate Aminotransferases; Brain; Brain Neoplasms; Cel

2012
Blood glutamate scavengers prolong the survival of rats and mice with brain-implanted gliomas.
    Investigational new drugs, 2012, Volume: 30, Issue:6

    Topics: Animals; Antineoplastic Agents, Alkylating; Aspartate Aminotransferases; Brain; Brain Neoplasms; Cel

2012
Blood glutamate scavengers prolong the survival of rats and mice with brain-implanted gliomas.
    Investigational new drugs, 2012, Volume: 30, Issue:6

    Topics: Animals; Antineoplastic Agents, Alkylating; Aspartate Aminotransferases; Brain; Brain Neoplasms; Cel

2012
Blood glutamate scavengers prolong the survival of rats and mice with brain-implanted gliomas.
    Investigational new drugs, 2012, Volume: 30, Issue:6

    Topics: Animals; Antineoplastic Agents, Alkylating; Aspartate Aminotransferases; Brain; Brain Neoplasms; Cel

2012
Blood glutamate scavengers prolong the survival of rats and mice with brain-implanted gliomas.
    Investigational new drugs, 2012, Volume: 30, Issue:6

    Topics: Animals; Antineoplastic Agents, Alkylating; Aspartate Aminotransferases; Brain; Brain Neoplasms; Cel

2012
Blood glutamate scavengers prolong the survival of rats and mice with brain-implanted gliomas.
    Investigational new drugs, 2012, Volume: 30, Issue:6

    Topics: Animals; Antineoplastic Agents, Alkylating; Aspartate Aminotransferases; Brain; Brain Neoplasms; Cel

2012
Blood glutamate scavengers prolong the survival of rats and mice with brain-implanted gliomas.
    Investigational new drugs, 2012, Volume: 30, Issue:6

    Topics: Animals; Antineoplastic Agents, Alkylating; Aspartate Aminotransferases; Brain; Brain Neoplasms; Cel

2012
Blood glutamate scavengers prolong the survival of rats and mice with brain-implanted gliomas.
    Investigational new drugs, 2012, Volume: 30, Issue:6

    Topics: Animals; Antineoplastic Agents, Alkylating; Aspartate Aminotransferases; Brain; Brain Neoplasms; Cel

2012
Blood glutamate scavengers prolong the survival of rats and mice with brain-implanted gliomas.
    Investigational new drugs, 2012, Volume: 30, Issue:6

    Topics: Animals; Antineoplastic Agents, Alkylating; Aspartate Aminotransferases; Brain; Brain Neoplasms; Cel

2012
Dose dense 1 week on/1 week off temozolomide in recurrent glioma: a retrospective study.
    Journal of neuro-oncology, 2012, Volume: 108, Issue:1

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Disease-Free Survival;

2012
Dose dense 1 week on/1 week off temozolomide in recurrent glioma: a retrospective study.
    Journal of neuro-oncology, 2012, Volume: 108, Issue:1

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Disease-Free Survival;

2012
Dose dense 1 week on/1 week off temozolomide in recurrent glioma: a retrospective study.
    Journal of neuro-oncology, 2012, Volume: 108, Issue:1

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Disease-Free Survival;

2012
Twice-daily dosing of temozolomide in combination with fotemustine for the treatment of patients with refractory glioblastoma.
    Anticancer research, 2012, Volume: 32, Issue:3

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Dacarbazine; Drug Admi

2012
Twice-daily dosing of temozolomide in combination with fotemustine for the treatment of patients with refractory glioblastoma.
    Anticancer research, 2012, Volume: 32, Issue:3

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Dacarbazine; Drug Admi

2012
Twice-daily dosing of temozolomide in combination with fotemustine for the treatment of patients with refractory glioblastoma.
    Anticancer research, 2012, Volume: 32, Issue:3

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Dacarbazine; Drug Admi

2012
Impact of antiepileptic drugs on thrombocytopenia in glioblastoma patients treated with standard chemoradiotherapy.
    Journal of neuro-oncology, 2012, Volume: 108, Issue:3

    Topics: Anticonvulsants; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Dacarbazine;

2012
Impact of antiepileptic drugs on thrombocytopenia in glioblastoma patients treated with standard chemoradiotherapy.
    Journal of neuro-oncology, 2012, Volume: 108, Issue:3

    Topics: Anticonvulsants; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Dacarbazine;

2012
Impact of antiepileptic drugs on thrombocytopenia in glioblastoma patients treated with standard chemoradiotherapy.
    Journal of neuro-oncology, 2012, Volume: 108, Issue:3

    Topics: Anticonvulsants; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Dacarbazine;

2012
MGMT gene promoter methylation as a potent prognostic factor in glioblastoma treated with temozolomide-based chemoradiotherapy: a single-institution study.
    International journal of radiation oncology, biology, physics, 2012, Nov-01, Volume: 84, Issue:3

    Topics: Adult; Age Factors; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Disease-F

2012
MGMT gene promoter methylation as a potent prognostic factor in glioblastoma treated with temozolomide-based chemoradiotherapy: a single-institution study.
    International journal of radiation oncology, biology, physics, 2012, Nov-01, Volume: 84, Issue:3

    Topics: Adult; Age Factors; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Disease-F

2012
MGMT gene promoter methylation as a potent prognostic factor in glioblastoma treated with temozolomide-based chemoradiotherapy: a single-institution study.
    International journal of radiation oncology, biology, physics, 2012, Nov-01, Volume: 84, Issue:3

    Topics: Adult; Age Factors; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Disease-F

2012
Proton and carbon ion radiotherapy for primary brain tumors delivered with active raster scanning at the Heidelberg Ion Therapy Center (HIT): early treatment results and study concepts.
    Radiation oncology (London, England), 2012, Mar-21, Volume: 7

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Brain Neoplasms; Carbon; Child; Combined Modality Th

2012
Proton and carbon ion radiotherapy for primary brain tumors delivered with active raster scanning at the Heidelberg Ion Therapy Center (HIT): early treatment results and study concepts.
    Radiation oncology (London, England), 2012, Mar-21, Volume: 7

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Brain Neoplasms; Carbon; Child; Combined Modality Th

2012
Proton and carbon ion radiotherapy for primary brain tumors delivered with active raster scanning at the Heidelberg Ion Therapy Center (HIT): early treatment results and study concepts.
    Radiation oncology (London, England), 2012, Mar-21, Volume: 7

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Brain Neoplasms; Carbon; Child; Combined Modality Th

2012
Superselective intra-arterial cerebral infusion of novel agents after blood-brain disruption for the treatment of recurrent glioblastoma multiforme: a technical case series.
    Neurosurgery clinics of North America, 2012, Volume: 23, Issue:2

    Topics: Adult; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Bevacizumab

2012
Superselective intra-arterial cerebral infusion of novel agents after blood-brain disruption for the treatment of recurrent glioblastoma multiforme: a technical case series.
    Neurosurgery clinics of North America, 2012, Volume: 23, Issue:2

    Topics: Adult; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Bevacizumab

2012
Superselective intra-arterial cerebral infusion of novel agents after blood-brain disruption for the treatment of recurrent glioblastoma multiforme: a technical case series.
    Neurosurgery clinics of North America, 2012, Volume: 23, Issue:2

    Topics: Adult; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Bevacizumab

2012
Successful pregnancy and delivery after concomitant temozolomide and radiotherapy treatment of glioblastoma multiforme.
    Clinical oncology (Royal College of Radiologists (Great Britain)), 2012, Volume: 24, Issue:4

    Topics: Adult; Antineoplastic Agents; Brain Neoplasms; Chemoradiotherapy; Dacarbazine; Female; Glioblastoma;

2012
Successful pregnancy and delivery after concomitant temozolomide and radiotherapy treatment of glioblastoma multiforme.
    Clinical oncology (Royal College of Radiologists (Great Britain)), 2012, Volume: 24, Issue:4

    Topics: Adult; Antineoplastic Agents; Brain Neoplasms; Chemoradiotherapy; Dacarbazine; Female; Glioblastoma;

2012
Successful pregnancy and delivery after concomitant temozolomide and radiotherapy treatment of glioblastoma multiforme.
    Clinical oncology (Royal College of Radiologists (Great Britain)), 2012, Volume: 24, Issue:4

    Topics: Adult; Antineoplastic Agents; Brain Neoplasms; Chemoradiotherapy; Dacarbazine; Female; Glioblastoma;

2012
Expression of O⁶-methylguanine DNA methyltransferase (MGMT) and immunohistochemical analysis of 12 pineal parenchymal tumors.
    Neuropathology : official journal of the Japanese Society of Neuropathology, 2012, Volume: 32, Issue:6

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; DNA Modification Methy

2012
Expression of O⁶-methylguanine DNA methyltransferase (MGMT) and immunohistochemical analysis of 12 pineal parenchymal tumors.
    Neuropathology : official journal of the Japanese Society of Neuropathology, 2012, Volume: 32, Issue:6

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; DNA Modification Methy

2012
Expression of O⁶-methylguanine DNA methyltransferase (MGMT) and immunohistochemical analysis of 12 pineal parenchymal tumors.
    Neuropathology : official journal of the Japanese Society of Neuropathology, 2012, Volume: 32, Issue:6

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; DNA Modification Methy

2012
Smac mimetic sensitizes glioblastoma cells to Temozolomide-induced apoptosis in a RIP1- and NF-κB-dependent manner.
    Oncogene, 2013, Feb-21, Volume: 32, Issue:8

    Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Apoptosis Regulatory Proteins; Biomimetic

2013
Smac mimetic sensitizes glioblastoma cells to Temozolomide-induced apoptosis in a RIP1- and NF-κB-dependent manner.
    Oncogene, 2013, Feb-21, Volume: 32, Issue:8

    Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Apoptosis Regulatory Proteins; Biomimetic

2013
Smac mimetic sensitizes glioblastoma cells to Temozolomide-induced apoptosis in a RIP1- and NF-κB-dependent manner.
    Oncogene, 2013, Feb-21, Volume: 32, Issue:8

    Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Apoptosis Regulatory Proteins; Biomimetic

2013
SSBP2 variants are associated with survival in glioblastoma patients.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2012, Jun-01, Volume: 18, Issue:11

    Topics: Brain Neoplasms; Dacarbazine; DNA-Binding Proteins; Female; Genome-Wide Association Study; Glioblast

2012
SSBP2 variants are associated with survival in glioblastoma patients.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2012, Jun-01, Volume: 18, Issue:11

    Topics: Brain Neoplasms; Dacarbazine; DNA-Binding Proteins; Female; Genome-Wide Association Study; Glioblast

2012
SSBP2 variants are associated with survival in glioblastoma patients.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2012, Jun-01, Volume: 18, Issue:11

    Topics: Brain Neoplasms; Dacarbazine; DNA-Binding Proteins; Female; Genome-Wide Association Study; Glioblast

2012
Paradoxical relationship between the degree of EGFR amplification and outcome in glioblastomas.
    The American journal of surgical pathology, 2012, Volume: 36, Issue:8

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Biomarkers, Tumor; Brain Neoplasm

2012
Paradoxical relationship between the degree of EGFR amplification and outcome in glioblastomas.
    The American journal of surgical pathology, 2012, Volume: 36, Issue:8

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Biomarkers, Tumor; Brain Neoplasm

2012
Paradoxical relationship between the degree of EGFR amplification and outcome in glioblastomas.
    The American journal of surgical pathology, 2012, Volume: 36, Issue:8

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Biomarkers, Tumor; Brain Neoplasm

2012
Temozolomide loaded PLGA-based superparamagnetic nanoparticles for magnetic resonance imaging and treatment of malignant glioma.
    International journal of pharmaceutics, 2012, Jul-01, Volume: 430, Issue:1-2

    Topics: Animals; Antineoplastic Agents, Alkylating; Biological Transport; Brain Neoplasms; Cell Line, Tumor;

2012
Temozolomide loaded PLGA-based superparamagnetic nanoparticles for magnetic resonance imaging and treatment of malignant glioma.
    International journal of pharmaceutics, 2012, Jul-01, Volume: 430, Issue:1-2

    Topics: Animals; Antineoplastic Agents, Alkylating; Biological Transport; Brain Neoplasms; Cell Line, Tumor;

2012
Temozolomide loaded PLGA-based superparamagnetic nanoparticles for magnetic resonance imaging and treatment of malignant glioma.
    International journal of pharmaceutics, 2012, Jul-01, Volume: 430, Issue:1-2

    Topics: Animals; Antineoplastic Agents, Alkylating; Biological Transport; Brain Neoplasms; Cell Line, Tumor;

2012
Rational incorporation of selenium into temozolomide elicits superior antitumor activity associated with both apoptotic and autophagic cell death.
    PloS one, 2012, Volume: 7, Issue:4

    Topics: Animals; Antineoplastic Agents, Alkylating; Apoptosis; Apoptosis Regulatory Proteins; Autophagy; Bec

2012
Rational incorporation of selenium into temozolomide elicits superior antitumor activity associated with both apoptotic and autophagic cell death.
    PloS one, 2012, Volume: 7, Issue:4

    Topics: Animals; Antineoplastic Agents, Alkylating; Apoptosis; Apoptosis Regulatory Proteins; Autophagy; Bec

2012
Rational incorporation of selenium into temozolomide elicits superior antitumor activity associated with both apoptotic and autophagic cell death.
    PloS one, 2012, Volume: 7, Issue:4

    Topics: Animals; Antineoplastic Agents, Alkylating; Apoptosis; Apoptosis Regulatory Proteins; Autophagy; Bec

2012
Radiotherapy with concurrent or sequential temozolomide in elderly patients with glioblastoma multiforme.
    Journal of medical imaging and radiation oncology, 2012, Volume: 56, Issue:2

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbaz

2012
Radiotherapy with concurrent or sequential temozolomide in elderly patients with glioblastoma multiforme.
    Journal of medical imaging and radiation oncology, 2012, Volume: 56, Issue:2

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbaz

2012
Radiotherapy with concurrent or sequential temozolomide in elderly patients with glioblastoma multiforme.
    Journal of medical imaging and radiation oncology, 2012, Volume: 56, Issue:2

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbaz

2012
High-dose methotrexate and temozolomide associated with intrathecal liposomal cytarabine for the treatment of primary or secondary central nervous system lymphoma: a preliminary experience.
    Clinical neurology and neurosurgery, 2012, Volume: 114, Issue:10

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Central Nervous System Neopla

2012
High-dose methotrexate and temozolomide associated with intrathecal liposomal cytarabine for the treatment of primary or secondary central nervous system lymphoma: a preliminary experience.
    Clinical neurology and neurosurgery, 2012, Volume: 114, Issue:10

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Central Nervous System Neopla

2012
High-dose methotrexate and temozolomide associated with intrathecal liposomal cytarabine for the treatment of primary or secondary central nervous system lymphoma: a preliminary experience.
    Clinical neurology and neurosurgery, 2012, Volume: 114, Issue:10

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Central Nervous System Neopla

2012
MicroRNA-21 inhibitor sensitizes human glioblastoma U251 stem cells to chemotherapeutic drug temozolomide.
    Journal of molecular neuroscience : MN, 2012, Volume: 47, Issue:2

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Dacarbazine; Glioblastoma; Hum

2012
MicroRNA-21 inhibitor sensitizes human glioblastoma U251 stem cells to chemotherapeutic drug temozolomide.
    Journal of molecular neuroscience : MN, 2012, Volume: 47, Issue:2

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Dacarbazine; Glioblastoma; Hum

2012
MicroRNA-21 inhibitor sensitizes human glioblastoma U251 stem cells to chemotherapeutic drug temozolomide.
    Journal of molecular neuroscience : MN, 2012, Volume: 47, Issue:2

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Dacarbazine; Glioblastoma; Hum

2012
DW-MRI as a biomarker to compare therapeutic outcomes in radiotherapy regimens incorporating temozolomide or gemcitabine in glioblastoma.
    PloS one, 2012, Volume: 7, Issue:4

    Topics: Animals; Antineoplastic Agents, Alkylating; Biomarkers; Brain Neoplasms; Cell Line; Chemoradiotherap

2012
DW-MRI as a biomarker to compare therapeutic outcomes in radiotherapy regimens incorporating temozolomide or gemcitabine in glioblastoma.
    PloS one, 2012, Volume: 7, Issue:4

    Topics: Animals; Antineoplastic Agents, Alkylating; Biomarkers; Brain Neoplasms; Cell Line; Chemoradiotherap

2012
DW-MRI as a biomarker to compare therapeutic outcomes in radiotherapy regimens incorporating temozolomide or gemcitabine in glioblastoma.
    PloS one, 2012, Volume: 7, Issue:4

    Topics: Animals; Antineoplastic Agents, Alkylating; Biomarkers; Brain Neoplasms; Cell Line; Chemoradiotherap

2012
Radiotherapy and temozolomide in anaplastic astrocytoma: a retrospective multicenter study by the Central Nervous System Study Group of AIRO (Italian Association of Radiation Oncology).
    Neuro-oncology, 2012, Volume: 14, Issue:6

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chem

2012
Radiotherapy and temozolomide in anaplastic astrocytoma: a retrospective multicenter study by the Central Nervous System Study Group of AIRO (Italian Association of Radiation Oncology).
    Neuro-oncology, 2012, Volume: 14, Issue:6

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chem

2012
Radiotherapy and temozolomide in anaplastic astrocytoma: a retrospective multicenter study by the Central Nervous System Study Group of AIRO (Italian Association of Radiation Oncology).
    Neuro-oncology, 2012, Volume: 14, Issue:6

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chem

2012
Up-regulation of endogenous PML induced by a combination of interferon-beta and temozolomide enhances p73/YAP-mediated apoptosis in glioblastoma.
    Cancer letters, 2012, Oct-28, Volume: 323, Issue:2

    Topics: Adaptor Proteins, Signal Transducing; Apoptosis; Base Sequence; Blotting, Western; Brain Neoplasms;

2012
Up-regulation of endogenous PML induced by a combination of interferon-beta and temozolomide enhances p73/YAP-mediated apoptosis in glioblastoma.
    Cancer letters, 2012, Oct-28, Volume: 323, Issue:2

    Topics: Adaptor Proteins, Signal Transducing; Apoptosis; Base Sequence; Blotting, Western; Brain Neoplasms;

2012
Up-regulation of endogenous PML induced by a combination of interferon-beta and temozolomide enhances p73/YAP-mediated apoptosis in glioblastoma.
    Cancer letters, 2012, Oct-28, Volume: 323, Issue:2

    Topics: Adaptor Proteins, Signal Transducing; Apoptosis; Base Sequence; Blotting, Western; Brain Neoplasms;

2012
Efficacy of clinically relevant temozolomide dosing schemes in glioblastoma cancer stem cell lines.
    Journal of neuro-oncology, 2012, Volume: 109, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Dacarbazine; DNA Modification

2012
Efficacy of clinically relevant temozolomide dosing schemes in glioblastoma cancer stem cell lines.
    Journal of neuro-oncology, 2012, Volume: 109, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Dacarbazine; DNA Modification

2012
Efficacy of clinically relevant temozolomide dosing schemes in glioblastoma cancer stem cell lines.
    Journal of neuro-oncology, 2012, Volume: 109, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Dacarbazine; DNA Modification

2012
Distinct molecular mechanisms of acquired resistance to temozolomide in glioblastoma cells.
    Journal of neurochemistry, 2012, Volume: 122, Issue:2

    Topics: Antineoplastic Agents, Alkylating; Blotting, Western; Brain Neoplasms; Cell Cycle; Cell Line, Tumor;

2012
Distinct molecular mechanisms of acquired resistance to temozolomide in glioblastoma cells.
    Journal of neurochemistry, 2012, Volume: 122, Issue:2

    Topics: Antineoplastic Agents, Alkylating; Blotting, Western; Brain Neoplasms; Cell Cycle; Cell Line, Tumor;

2012
Distinct molecular mechanisms of acquired resistance to temozolomide in glioblastoma cells.
    Journal of neurochemistry, 2012, Volume: 122, Issue:2

    Topics: Antineoplastic Agents, Alkylating; Blotting, Western; Brain Neoplasms; Cell Cycle; Cell Line, Tumor;

2012
miR-181d: a predictive glioblastoma biomarker that downregulates MGMT expression.
    Neuro-oncology, 2012, Volume: 14, Issue:6

    Topics: Antineoplastic Agents, Alkylating; Biomarkers, Tumor; Brain Neoplasms; Dacarbazine; DNA Modification

2012
miR-181d: a predictive glioblastoma biomarker that downregulates MGMT expression.
    Neuro-oncology, 2012, Volume: 14, Issue:6

    Topics: Antineoplastic Agents, Alkylating; Biomarkers, Tumor; Brain Neoplasms; Dacarbazine; DNA Modification

2012
miR-181d: a predictive glioblastoma biomarker that downregulates MGMT expression.
    Neuro-oncology, 2012, Volume: 14, Issue:6

    Topics: Antineoplastic Agents, Alkylating; Biomarkers, Tumor; Brain Neoplasms; Dacarbazine; DNA Modification

2012
Prognosis of pediatric high-grade gliomas with temozolomide treatment: a retrospective, multicenter study.
    Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 2012, Volume: 28, Issue:7

    Topics: Adolescent; Antineoplastic Agents, Alkylating; Brain Neoplasms; Child; Child, Preschool; Dacarbazine

2012
Prognosis of pediatric high-grade gliomas with temozolomide treatment: a retrospective, multicenter study.
    Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 2012, Volume: 28, Issue:7

    Topics: Adolescent; Antineoplastic Agents, Alkylating; Brain Neoplasms; Child; Child, Preschool; Dacarbazine

2012
Prognosis of pediatric high-grade gliomas with temozolomide treatment: a retrospective, multicenter study.
    Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 2012, Volume: 28, Issue:7

    Topics: Adolescent; Antineoplastic Agents, Alkylating; Brain Neoplasms; Child; Child, Preschool; Dacarbazine

2012
Treatment of elderly patients with glioblastoma.
    The Lancet. Oncology, 2012, Volume: 13, Issue:7

    Topics: Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neoplasms; Dacarbazine; Female; Humans; Male;

2012
Treatment of elderly patients with glioblastoma.
    The Lancet. Oncology, 2012, Volume: 13, Issue:7

    Topics: Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neoplasms; Dacarbazine; Female; Humans; Male;

2012
Treatment of elderly patients with glioblastoma.
    The Lancet. Oncology, 2012, Volume: 13, Issue:7

    Topics: Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neoplasms; Dacarbazine; Female; Humans; Male;

2012
A retrospective pooled analysis of response patterns and risk factors in recurrent malignant glioma patients receiving a nitrosourea-based chemotherapy.
    Journal of translational medicine, 2012, May-14, Volume: 10

    Topics: Adult; Aged; Brain Neoplasms; Dacarbazine; Female; Glioma; Humans; Logistic Models; Male; Middle Age

2012
A retrospective pooled analysis of response patterns and risk factors in recurrent malignant glioma patients receiving a nitrosourea-based chemotherapy.
    Journal of translational medicine, 2012, May-14, Volume: 10

    Topics: Adult; Aged; Brain Neoplasms; Dacarbazine; Female; Glioma; Humans; Logistic Models; Male; Middle Age

2012
A retrospective pooled analysis of response patterns and risk factors in recurrent malignant glioma patients receiving a nitrosourea-based chemotherapy.
    Journal of translational medicine, 2012, May-14, Volume: 10

    Topics: Adult; Aged; Brain Neoplasms; Dacarbazine; Female; Glioma; Humans; Logistic Models; Male; Middle Age

2012
Intracranial MEMS based temozolomide delivery in a 9L rat gliosarcoma model.
    Biomaterials, 2012, Volume: 33, Issue:23

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Drug Delivery Systems; Equ

2012
Intracranial MEMS based temozolomide delivery in a 9L rat gliosarcoma model.
    Biomaterials, 2012, Volume: 33, Issue:23

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Drug Delivery Systems; Equ

2012
Intracranial MEMS based temozolomide delivery in a 9L rat gliosarcoma model.
    Biomaterials, 2012, Volume: 33, Issue:23

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Drug Delivery Systems; Equ

2012
Integrin α5β1 plays a critical role in resistance to temozolomide by interfering with the p53 pathway in high-grade glioma.
    Cancer research, 2012, Jul-15, Volume: 72, Issue:14

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Dacarbazine; Drug Res

2012
Integrin α5β1 plays a critical role in resistance to temozolomide by interfering with the p53 pathway in high-grade glioma.
    Cancer research, 2012, Jul-15, Volume: 72, Issue:14

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Dacarbazine; Drug Res

2012
Integrin α5β1 plays a critical role in resistance to temozolomide by interfering with the p53 pathway in high-grade glioma.
    Cancer research, 2012, Jul-15, Volume: 72, Issue:14

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Dacarbazine; Drug Res

2012
The impact of bevacizumab on temozolomide concentrations in intracranial U87 gliomas.
    Cancer chemotherapy and pharmacology, 2012, Volume: 70, Issue:1

    Topics: Animals; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Area Und

2012
The impact of bevacizumab on temozolomide concentrations in intracranial U87 gliomas.
    Cancer chemotherapy and pharmacology, 2012, Volume: 70, Issue:1

    Topics: Animals; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Area Und

2012
The impact of bevacizumab on temozolomide concentrations in intracranial U87 gliomas.
    Cancer chemotherapy and pharmacology, 2012, Volume: 70, Issue:1

    Topics: Animals; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Area Und

2012
Change in platelet levels during radiotherapy with concurrent and adjuvant temozolomide for the treatment of glioblastoma: a novel prognostic factor for survival.
    Journal of cancer research and clinical oncology, 2012, Volume: 138, Issue:10

    Topics: Antineoplastic Agents, Alkylating; Blood Platelets; Brain Neoplasms; Chemotherapy, Adjuvant; Combine

2012
Change in platelet levels during radiotherapy with concurrent and adjuvant temozolomide for the treatment of glioblastoma: a novel prognostic factor for survival.
    Journal of cancer research and clinical oncology, 2012, Volume: 138, Issue:10

    Topics: Antineoplastic Agents, Alkylating; Blood Platelets; Brain Neoplasms; Chemotherapy, Adjuvant; Combine

2012
Change in platelet levels during radiotherapy with concurrent and adjuvant temozolomide for the treatment of glioblastoma: a novel prognostic factor for survival.
    Journal of cancer research and clinical oncology, 2012, Volume: 138, Issue:10

    Topics: Antineoplastic Agents, Alkylating; Blood Platelets; Brain Neoplasms; Chemotherapy, Adjuvant; Combine

2012
Waiting times before initiation of radiotherapy might not affect outcomes for patients with glioblastoma: a French retrospective analysis of patients treated in the era of concomitant temozolomide and radiotherapy.
    Journal of neuro-oncology, 2012, Volume: 109, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherap

2012
Waiting times before initiation of radiotherapy might not affect outcomes for patients with glioblastoma: a French retrospective analysis of patients treated in the era of concomitant temozolomide and radiotherapy.
    Journal of neuro-oncology, 2012, Volume: 109, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherap

2012
Waiting times before initiation of radiotherapy might not affect outcomes for patients with glioblastoma: a French retrospective analysis of patients treated in the era of concomitant temozolomide and radiotherapy.
    Journal of neuro-oncology, 2012, Volume: 109, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherap

2012
Resection of gliomas in the cingulate gyrus: functional outcome and survival.
    Journal of neuro-oncology, 2012, Volume: 109, Issue:2

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Female; Glioma; Gyrus

2012
Resection of gliomas in the cingulate gyrus: functional outcome and survival.
    Journal of neuro-oncology, 2012, Volume: 109, Issue:2

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Female; Glioma; Gyrus

2012
Resection of gliomas in the cingulate gyrus: functional outcome and survival.
    Journal of neuro-oncology, 2012, Volume: 109, Issue:2

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Female; Glioma; Gyrus

2012
Initial treatment patterns over time for anaplastic oligodendroglial tumors.
    Neuro-oncology, 2012, Volume: 14, Issue:6

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chem

2012
Initial treatment patterns over time for anaplastic oligodendroglial tumors.
    Neuro-oncology, 2012, Volume: 14, Issue:6

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chem

2012
Initial treatment patterns over time for anaplastic oligodendroglial tumors.
    Neuro-oncology, 2012, Volume: 14, Issue:6

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chem

2012
Combination hyperbaric oxygen and temozolomide therapy in C6 rat glioma model.
    Acta cirurgica brasileira, 2012, Volume: 27, Issue:6

    Topics: Animals; Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Combined M

2012
Combination hyperbaric oxygen and temozolomide therapy in C6 rat glioma model.
    Acta cirurgica brasileira, 2012, Volume: 27, Issue:6

    Topics: Animals; Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Combined M

2012
Combination hyperbaric oxygen and temozolomide therapy in C6 rat glioma model.
    Acta cirurgica brasileira, 2012, Volume: 27, Issue:6

    Topics: Animals; Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Combined M

2012
Radiotherapy and concomitant temozolomide may improve survival of elderly patients with glioblastoma.
    Journal of neuro-oncology, 2012, Volume: 109, Issue:2

    Topics: Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Thera

2012
Radiotherapy and concomitant temozolomide may improve survival of elderly patients with glioblastoma.
    Journal of neuro-oncology, 2012, Volume: 109, Issue:2

    Topics: Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Thera

2012
Radiotherapy and concomitant temozolomide may improve survival of elderly patients with glioblastoma.
    Journal of neuro-oncology, 2012, Volume: 109, Issue:2

    Topics: Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Thera

2012
Late and prolonged pseudoprogression in glioblastoma after treatment with lomustine and temozolomide.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2012, Jul-20, Volume: 30, Issue:21

    Topics: Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms;

2012
Late and prolonged pseudoprogression in glioblastoma after treatment with lomustine and temozolomide.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2012, Jul-20, Volume: 30, Issue:21

    Topics: Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms;

2012
Late and prolonged pseudoprogression in glioblastoma after treatment with lomustine and temozolomide.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2012, Jul-20, Volume: 30, Issue:21

    Topics: Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms;

2012
Valproic acid downregulates the expression of MGMT and sensitizes temozolomide-resistant glioma cells.
    Journal of biomedicine & biotechnology, 2012, Volume: 2012

    Topics: Animals; Brain Neoplasms; Cell Line, Tumor; Dacarbazine; DNA Modification Methylases; DNA Repair Enz

2012
Valproic acid downregulates the expression of MGMT and sensitizes temozolomide-resistant glioma cells.
    Journal of biomedicine & biotechnology, 2012, Volume: 2012

    Topics: Animals; Brain Neoplasms; Cell Line, Tumor; Dacarbazine; DNA Modification Methylases; DNA Repair Enz

2012
Valproic acid downregulates the expression of MGMT and sensitizes temozolomide-resistant glioma cells.
    Journal of biomedicine & biotechnology, 2012, Volume: 2012

    Topics: Animals; Brain Neoplasms; Cell Line, Tumor; Dacarbazine; DNA Modification Methylases; DNA Repair Enz

2012
Safety and efficacy of Gliadel wafers for newly diagnosed and recurrent glioblastoma.
    Acta neurochirurgica, 2012, Volume: 154, Issue:8

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Carmustine; Daca

2012
Safety and efficacy of Gliadel wafers for newly diagnosed and recurrent glioblastoma.
    Acta neurochirurgica, 2012, Volume: 154, Issue:8

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Carmustine; Daca

2012
Safety and efficacy of Gliadel wafers for newly diagnosed and recurrent glioblastoma.
    Acta neurochirurgica, 2012, Volume: 154, Issue:8

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Carmustine; Daca

2012
Bevacizumab for glioblastoma multiforme after traumatic subarachnoid hemorrhage.
    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2012, Volume: 19, Issue:9

    Topics: Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Antineoplastic Agents, Alkylating; Bevac

2012
Bevacizumab for glioblastoma multiforme after traumatic subarachnoid hemorrhage.
    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2012, Volume: 19, Issue:9

    Topics: Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Antineoplastic Agents, Alkylating; Bevac

2012
Bevacizumab for glioblastoma multiforme after traumatic subarachnoid hemorrhage.
    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2012, Volume: 19, Issue:9

    Topics: Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Antineoplastic Agents, Alkylating; Bevac

2012
Knockdown of CDK6 enhances glioma sensitivity to chemotherapy.
    Oncology reports, 2012, Volume: 28, Issue:3

    Topics: Animals; Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neoplasms; Cell Line, Tumor; Cell Pro

2012
Knockdown of CDK6 enhances glioma sensitivity to chemotherapy.
    Oncology reports, 2012, Volume: 28, Issue:3

    Topics: Animals; Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neoplasms; Cell Line, Tumor; Cell Pro

2012
Knockdown of CDK6 enhances glioma sensitivity to chemotherapy.
    Oncology reports, 2012, Volume: 28, Issue:3

    Topics: Animals; Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neoplasms; Cell Line, Tumor; Cell Pro

2012
IDH1 mutation as a potential novel biomarker for distinguishing pseudoprogression from true progression in patients with glioblastoma treated with temozolomide and radiotherapy.
    Brain tumor pathology, 2013, Volume: 30, Issue:2

    Topics: Adult; Antineoplastic Agents, Alkylating; Biomarkers, Tumor; Brain Neoplasms; Combined Modality Ther

2013
IDH1 mutation as a potential novel biomarker for distinguishing pseudoprogression from true progression in patients with glioblastoma treated with temozolomide and radiotherapy.
    Brain tumor pathology, 2013, Volume: 30, Issue:2

    Topics: Adult; Antineoplastic Agents, Alkylating; Biomarkers, Tumor; Brain Neoplasms; Combined Modality Ther

2013
IDH1 mutation as a potential novel biomarker for distinguishing pseudoprogression from true progression in patients with glioblastoma treated with temozolomide and radiotherapy.
    Brain tumor pathology, 2013, Volume: 30, Issue:2

    Topics: Adult; Antineoplastic Agents, Alkylating; Biomarkers, Tumor; Brain Neoplasms; Combined Modality Ther

2013
MicroRNA-21 inhibition enhances in vitro chemosensitivity of temozolomide-resistant glioblastoma cells.
    Anticancer research, 2012, Volume: 32, Issue:7

    Topics: Antineoplastic Agents, Alkylating; Biomarkers, Tumor; Brain Neoplasms; Cell Line, Tumor; Combined Mo

2012
MicroRNA-21 inhibition enhances in vitro chemosensitivity of temozolomide-resistant glioblastoma cells.
    Anticancer research, 2012, Volume: 32, Issue:7

    Topics: Antineoplastic Agents, Alkylating; Biomarkers, Tumor; Brain Neoplasms; Cell Line, Tumor; Combined Mo

2012
MicroRNA-21 inhibition enhances in vitro chemosensitivity of temozolomide-resistant glioblastoma cells.
    Anticancer research, 2012, Volume: 32, Issue:7

    Topics: Antineoplastic Agents, Alkylating; Biomarkers, Tumor; Brain Neoplasms; Cell Line, Tumor; Combined Mo

2012
Hyperoxia resensitizes chemoresistant human glioblastoma cells to temozolomide.
    Journal of neuro-oncology, 2012, Volume: 109, Issue:3

    Topics: Antineoplastic Agents, Alkylating; Apoptosis; Blotting, Western; Brain Neoplasms; Cell Line, Tumor;

2012
Hyperoxia resensitizes chemoresistant human glioblastoma cells to temozolomide.
    Journal of neuro-oncology, 2012, Volume: 109, Issue:3

    Topics: Antineoplastic Agents, Alkylating; Apoptosis; Blotting, Western; Brain Neoplasms; Cell Line, Tumor;

2012
Hyperoxia resensitizes chemoresistant human glioblastoma cells to temozolomide.
    Journal of neuro-oncology, 2012, Volume: 109, Issue:3

    Topics: Antineoplastic Agents, Alkylating; Apoptosis; Blotting, Western; Brain Neoplasms; Cell Line, Tumor;

2012
Radiation necrosis of a high-grade glioma.
    Medicine and health, Rhode Island, 2012, Volume: 95, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Antineoplastic Agents, Phytogenic; Brain Neoplasms; Dacarbazine;

2012
Radiation necrosis of a high-grade glioma.
    Medicine and health, Rhode Island, 2012, Volume: 95, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Antineoplastic Agents, Phytogenic; Brain Neoplasms; Dacarbazine;

2012
Radiation necrosis of a high-grade glioma.
    Medicine and health, Rhode Island, 2012, Volume: 95, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Antineoplastic Agents, Phytogenic; Brain Neoplasms; Dacarbazine;

2012
Helping patients make the best decision regarding duration of temozolomide chemotherapy treatment.
    Continuum (Minneapolis, Minn.), 2012, Volume: 18, Issue:2

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Female;

2012
Helping patients make the best decision regarding duration of temozolomide chemotherapy treatment.
    Continuum (Minneapolis, Minn.), 2012, Volume: 18, Issue:2

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Female;

2012
Helping patients make the best decision regarding duration of temozolomide chemotherapy treatment.
    Continuum (Minneapolis, Minn.), 2012, Volume: 18, Issue:2

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Female;

2012
CXCR4-positive subset of glioma is enriched for cancer stem cells.
    Oncology research, 2011, Volume: 19, Issue:12

    Topics: AC133 Antigen; Animals; Antigens, CD; Antineoplastic Agents, Alkylating; Blotting, Western; Brain Ne

2011
CXCR4-positive subset of glioma is enriched for cancer stem cells.
    Oncology research, 2011, Volume: 19, Issue:12

    Topics: AC133 Antigen; Animals; Antigens, CD; Antineoplastic Agents, Alkylating; Blotting, Western; Brain Ne

2011
CXCR4-positive subset of glioma is enriched for cancer stem cells.
    Oncology research, 2011, Volume: 19, Issue:12

    Topics: AC133 Antigen; Animals; Antigens, CD; Antineoplastic Agents, Alkylating; Blotting, Western; Brain Ne

2011
Local delivery of slow-releasing temozolomide microspheres inhibits intracranial xenograft glioma growth.
    Journal of cancer research and clinical oncology, 2012, Volume: 138, Issue:12

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Growth Processes; Cell Line, Tumor

2012
Local delivery of slow-releasing temozolomide microspheres inhibits intracranial xenograft glioma growth.
    Journal of cancer research and clinical oncology, 2012, Volume: 138, Issue:12

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Growth Processes; Cell Line, Tumor

2012
Local delivery of slow-releasing temozolomide microspheres inhibits intracranial xenograft glioma growth.
    Journal of cancer research and clinical oncology, 2012, Volume: 138, Issue:12

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Growth Processes; Cell Line, Tumor

2012
O6-Methylguanine-methyltransferase (MGMT) promoter methylation status in glioma stem-like cells is correlated to temozolomide sensitivity under differentiation-promoting conditions.
    International journal of molecular sciences, 2012, Volume: 13, Issue:6

    Topics: Aged; Algorithms; Brain Neoplasms; Cell Differentiation; Cell Line, Tumor; Dacarbazine; DNA Methylat

2012
O6-Methylguanine-methyltransferase (MGMT) promoter methylation status in glioma stem-like cells is correlated to temozolomide sensitivity under differentiation-promoting conditions.
    International journal of molecular sciences, 2012, Volume: 13, Issue:6

    Topics: Aged; Algorithms; Brain Neoplasms; Cell Differentiation; Cell Line, Tumor; Dacarbazine; DNA Methylat

2012
O6-Methylguanine-methyltransferase (MGMT) promoter methylation status in glioma stem-like cells is correlated to temozolomide sensitivity under differentiation-promoting conditions.
    International journal of molecular sciences, 2012, Volume: 13, Issue:6

    Topics: Aged; Algorithms; Brain Neoplasms; Cell Differentiation; Cell Line, Tumor; Dacarbazine; DNA Methylat

2012
A restricted cell population propagates glioblastoma growth after chemotherapy.
    Nature, 2012, Aug-23, Volume: 488, Issue:7412

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Proliferation; Cell Tracking; Daca

2012
A restricted cell population propagates glioblastoma growth after chemotherapy.
    Nature, 2012, Aug-23, Volume: 488, Issue:7412

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Proliferation; Cell Tracking; Daca

2012
A restricted cell population propagates glioblastoma growth after chemotherapy.
    Nature, 2012, Aug-23, Volume: 488, Issue:7412

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Proliferation; Cell Tracking; Daca

2012
Interdisciplinary treatment of glioblastoma: analysis of prognostic factors and treatment results in unselected patients.
    Neoplasma, 2012, Volume: 59, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Female; Gli

2012
Interdisciplinary treatment of glioblastoma: analysis of prognostic factors and treatment results in unselected patients.
    Neoplasma, 2012, Volume: 59, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Female; Gli

2012
Interdisciplinary treatment of glioblastoma: analysis of prognostic factors and treatment results in unselected patients.
    Neoplasma, 2012, Volume: 59, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Female; Gli

2012
A population-based study on the effect of temozolomide in the treatment of glioblastoma multiforme.
    Neuro-oncology, 2012, Volume: 14, Issue:9

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Female;

2012
A population-based study on the effect of temozolomide in the treatment of glioblastoma multiforme.
    Neuro-oncology, 2012, Volume: 14, Issue:9

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Female;

2012
A population-based study on the effect of temozolomide in the treatment of glioblastoma multiforme.
    Neuro-oncology, 2012, Volume: 14, Issue:9

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Female;

2012
CT322, a VEGFR-2 antagonist, demonstrates anti-glioma efficacy in orthotopic brain tumor model as a single agent or in combination with temozolomide and radiation therapy.
    Journal of neuro-oncology, 2012, Volume: 110, Issue:1

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Cell Line, Tumor; Chemorad

2012
CT322, a VEGFR-2 antagonist, demonstrates anti-glioma efficacy in orthotopic brain tumor model as a single agent or in combination with temozolomide and radiation therapy.
    Journal of neuro-oncology, 2012, Volume: 110, Issue:1

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Cell Line, Tumor; Chemorad

2012
CT322, a VEGFR-2 antagonist, demonstrates anti-glioma efficacy in orthotopic brain tumor model as a single agent or in combination with temozolomide and radiation therapy.
    Journal of neuro-oncology, 2012, Volume: 110, Issue:1

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Cell Line, Tumor; Chemorad

2012
Presentation, management, and outcome of elderly patients with newly-diagnosed anaplastic astrocytoma.
    Journal of neuro-oncology, 2012, Volume: 110, Issue:2

    Topics: Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neoplasms; Combined M

2012
Presentation, management, and outcome of elderly patients with newly-diagnosed anaplastic astrocytoma.
    Journal of neuro-oncology, 2012, Volume: 110, Issue:2

    Topics: Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neoplasms; Combined M

2012
Presentation, management, and outcome of elderly patients with newly-diagnosed anaplastic astrocytoma.
    Journal of neuro-oncology, 2012, Volume: 110, Issue:2

    Topics: Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neoplasms; Combined M

2012
Glioblastoma therapy in the elderly: one age does not fit all.
    The Lancet. Oncology, 2012, Volume: 13, Issue:9

    Topics: Brain Neoplasms; Dacarbazine; Female; Glioblastoma; Humans; Male; Temozolomide

2012
Glioblastoma therapy in the elderly: one age does not fit all.
    The Lancet. Oncology, 2012, Volume: 13, Issue:9

    Topics: Brain Neoplasms; Dacarbazine; Female; Glioblastoma; Humans; Male; Temozolomide

2012
Glioblastoma therapy in the elderly: one age does not fit all.
    The Lancet. Oncology, 2012, Volume: 13, Issue:9

    Topics: Brain Neoplasms; Dacarbazine; Female; Glioblastoma; Humans; Male; Temozolomide

2012
Protracted low dose of oral vinorelbine and temozolomide with whole-brain radiotherapy in the treatment for breast cancer patients with brain metastases.
    Cancer chemotherapy and pharmacology, 2012, Volume: 70, Issue:4

    Topics: Administration, Oral; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms;

2012
Protracted low dose of oral vinorelbine and temozolomide with whole-brain radiotherapy in the treatment for breast cancer patients with brain metastases.
    Cancer chemotherapy and pharmacology, 2012, Volume: 70, Issue:4

    Topics: Administration, Oral; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms;

2012
Protracted low dose of oral vinorelbine and temozolomide with whole-brain radiotherapy in the treatment for breast cancer patients with brain metastases.
    Cancer chemotherapy and pharmacology, 2012, Volume: 70, Issue:4

    Topics: Administration, Oral; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms;

2012
The synergistic therapeutic effect of temozolomide and hyperbaric oxygen on glioma U251 cell lines is accompanied by alterations in vascular endothelial growth factor and multidrug resistance-associated protein-1 levels.
    The Journal of international medical research, 2012, Volume: 40, Issue:3

    Topics: Antineoplastic Agents, Alkylating; Apoptosis; ATP Binding Cassette Transporter, Subfamily B, Member

2012
The synergistic therapeutic effect of temozolomide and hyperbaric oxygen on glioma U251 cell lines is accompanied by alterations in vascular endothelial growth factor and multidrug resistance-associated protein-1 levels.
    The Journal of international medical research, 2012, Volume: 40, Issue:3

    Topics: Antineoplastic Agents, Alkylating; Apoptosis; ATP Binding Cassette Transporter, Subfamily B, Member

2012
The synergistic therapeutic effect of temozolomide and hyperbaric oxygen on glioma U251 cell lines is accompanied by alterations in vascular endothelial growth factor and multidrug resistance-associated protein-1 levels.
    The Journal of international medical research, 2012, Volume: 40, Issue:3

    Topics: Antineoplastic Agents, Alkylating; Apoptosis; ATP Binding Cassette Transporter, Subfamily B, Member

2012
Prognostic relevance of c-Myc and BMI1 expression in patients with glioblastoma.
    American journal of clinical pathology, 2012, Volume: 138, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modalit

2012
Prognostic relevance of c-Myc and BMI1 expression in patients with glioblastoma.
    American journal of clinical pathology, 2012, Volume: 138, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modalit

2012
Prognostic relevance of c-Myc and BMI1 expression in patients with glioblastoma.
    American journal of clinical pathology, 2012, Volume: 138, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modalit

2012
Cancer: Resolving the stem-cell debate.
    Nature, 2012, Aug-23, Volume: 488, Issue:7412

    Topics: Animals; Brain Neoplasms; Cell Lineage; Cell Tracking; Dacarbazine; Female; Glioblastoma; Humans; Ma

2012
Cancer: Resolving the stem-cell debate.
    Nature, 2012, Aug-23, Volume: 488, Issue:7412

    Topics: Animals; Brain Neoplasms; Cell Lineage; Cell Tracking; Dacarbazine; Female; Glioblastoma; Humans; Ma

2012
Cancer: Resolving the stem-cell debate.
    Nature, 2012, Aug-23, Volume: 488, Issue:7412

    Topics: Animals; Brain Neoplasms; Cell Lineage; Cell Tracking; Dacarbazine; Female; Glioblastoma; Humans; Ma

2012
Prognosis of patients with multifocal glioblastoma: a case-control study.
    Journal of neurosurgery, 2012, Volume: 117, Issue:4

    Topics: Aged; Antineoplastic Agents; Brain Neoplasms; Case-Control Studies; Cohort Studies; Combined Modalit

2012
Prognosis of patients with multifocal glioblastoma: a case-control study.
    Journal of neurosurgery, 2012, Volume: 117, Issue:4

    Topics: Aged; Antineoplastic Agents; Brain Neoplasms; Case-Control Studies; Cohort Studies; Combined Modalit

2012
Prognosis of patients with multifocal glioblastoma: a case-control study.
    Journal of neurosurgery, 2012, Volume: 117, Issue:4

    Topics: Aged; Antineoplastic Agents; Brain Neoplasms; Case-Control Studies; Cohort Studies; Combined Modalit

2012
Perillyl alcohol for the treatment of temozolomide-resistant gliomas.
    Molecular cancer therapeutics, 2012, Volume: 11, Issue:11

    Topics: Administration, Intranasal; Animals; Brain Neoplasms; Cell Death; Cell Line, Tumor; Cell Proliferati

2012
Perillyl alcohol for the treatment of temozolomide-resistant gliomas.
    Molecular cancer therapeutics, 2012, Volume: 11, Issue:11

    Topics: Administration, Intranasal; Animals; Brain Neoplasms; Cell Death; Cell Line, Tumor; Cell Proliferati

2012
Perillyl alcohol for the treatment of temozolomide-resistant gliomas.
    Molecular cancer therapeutics, 2012, Volume: 11, Issue:11

    Topics: Administration, Intranasal; Animals; Brain Neoplasms; Cell Death; Cell Line, Tumor; Cell Proliferati

2012
Potentiation of etoposide and temozolomide cytotoxicity by curcumin and turmeric force™ in brain tumor cell lines.
    Journal of complementary & integrative medicine, 2012, Aug-10, Volume: 9

    Topics: Antineoplastic Agents; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Phytogenic; Antineo

2012
Potentiation of etoposide and temozolomide cytotoxicity by curcumin and turmeric force™ in brain tumor cell lines.
    Journal of complementary & integrative medicine, 2012, Aug-10, Volume: 9

    Topics: Antineoplastic Agents; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Phytogenic; Antineo

2012
Potentiation of etoposide and temozolomide cytotoxicity by curcumin and turmeric force™ in brain tumor cell lines.
    Journal of complementary & integrative medicine, 2012, Aug-10, Volume: 9

    Topics: Antineoplastic Agents; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Phytogenic; Antineo

2012
The T genotype of the MGMT C>T (rs16906252) enhancer single-nucleotide polymorphism (SNP) is associated with promoter methylation and longer survival in glioblastoma patients.
    European journal of cancer (Oxford, England : 1990), 2013, Volume: 49, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cohort Studies;

2013
The T genotype of the MGMT C>T (rs16906252) enhancer single-nucleotide polymorphism (SNP) is associated with promoter methylation and longer survival in glioblastoma patients.
    European journal of cancer (Oxford, England : 1990), 2013, Volume: 49, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cohort Studies;

2013
The T genotype of the MGMT C>T (rs16906252) enhancer single-nucleotide polymorphism (SNP) is associated with promoter methylation and longer survival in glioblastoma patients.
    European journal of cancer (Oxford, England : 1990), 2013, Volume: 49, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cohort Studies;

2013
Methylation mediated silencing of miR-23b expression and its role in glioma stem cells.
    Neuroscience letters, 2012, Oct-24, Volume: 528, Issue:2

    Topics: Antineoplastic Agents; Azacitidine; Brain Neoplasms; Cell Cycle Checkpoints; Cell Line, Tumor; Cell

2012
Methylation mediated silencing of miR-23b expression and its role in glioma stem cells.
    Neuroscience letters, 2012, Oct-24, Volume: 528, Issue:2

    Topics: Antineoplastic Agents; Azacitidine; Brain Neoplasms; Cell Cycle Checkpoints; Cell Line, Tumor; Cell

2012
Methylation mediated silencing of miR-23b expression and its role in glioma stem cells.
    Neuroscience letters, 2012, Oct-24, Volume: 528, Issue:2

    Topics: Antineoplastic Agents; Azacitidine; Brain Neoplasms; Cell Cycle Checkpoints; Cell Line, Tumor; Cell

2012
Abbreviated course of radiation therapy with concurrent temozolomide for high-grade glioma in patients of advanced age or poor functional status.
    Journal of neuro-oncology, 2012, Volume: 110, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherap

2012
Abbreviated course of radiation therapy with concurrent temozolomide for high-grade glioma in patients of advanced age or poor functional status.
    Journal of neuro-oncology, 2012, Volume: 110, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherap

2012
Abbreviated course of radiation therapy with concurrent temozolomide for high-grade glioma in patients of advanced age or poor functional status.
    Journal of neuro-oncology, 2012, Volume: 110, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherap

2012
Fasting enhances the response of glioma to chemo- and radiotherapy.
    PloS one, 2012, Volume: 7, Issue:9

    Topics: Animals; Antineoplastic Agents, Alkylating; Astrocytoma; Blood Glucose; Body Weight; Brain Neoplasms

2012
Fasting enhances the response of glioma to chemo- and radiotherapy.
    PloS one, 2012, Volume: 7, Issue:9

    Topics: Animals; Antineoplastic Agents, Alkylating; Astrocytoma; Blood Glucose; Body Weight; Brain Neoplasms

2012
Fasting enhances the response of glioma to chemo- and radiotherapy.
    PloS one, 2012, Volume: 7, Issue:9

    Topics: Animals; Antineoplastic Agents, Alkylating; Astrocytoma; Blood Glucose; Body Weight; Brain Neoplasms

2012
Fasting enhances the response of glioma to chemo- and radiotherapy.
    PloS one, 2012, Volume: 7, Issue:9

    Topics: Animals; Antineoplastic Agents, Alkylating; Astrocytoma; Blood Glucose; Body Weight; Brain Neoplasms

2012
Fasting enhances the response of glioma to chemo- and radiotherapy.
    PloS one, 2012, Volume: 7, Issue:9

    Topics: Animals; Antineoplastic Agents, Alkylating; Astrocytoma; Blood Glucose; Body Weight; Brain Neoplasms

2012
Fasting enhances the response of glioma to chemo- and radiotherapy.
    PloS one, 2012, Volume: 7, Issue:9

    Topics: Animals; Antineoplastic Agents, Alkylating; Astrocytoma; Blood Glucose; Body Weight; Brain Neoplasms

2012
Fasting enhances the response of glioma to chemo- and radiotherapy.
    PloS one, 2012, Volume: 7, Issue:9

    Topics: Animals; Antineoplastic Agents, Alkylating; Astrocytoma; Blood Glucose; Body Weight; Brain Neoplasms

2012
Fasting enhances the response of glioma to chemo- and radiotherapy.
    PloS one, 2012, Volume: 7, Issue:9

    Topics: Animals; Antineoplastic Agents, Alkylating; Astrocytoma; Blood Glucose; Body Weight; Brain Neoplasms

2012
Fasting enhances the response of glioma to chemo- and radiotherapy.
    PloS one, 2012, Volume: 7, Issue:9

    Topics: Animals; Antineoplastic Agents, Alkylating; Astrocytoma; Blood Glucose; Body Weight; Brain Neoplasms

2012
Fasting enhances the response of glioma to chemo- and radiotherapy.
    PloS one, 2012, Volume: 7, Issue:9

    Topics: Animals; Antineoplastic Agents, Alkylating; Astrocytoma; Blood Glucose; Body Weight; Brain Neoplasms

2012
Fasting enhances the response of glioma to chemo- and radiotherapy.
    PloS one, 2012, Volume: 7, Issue:9

    Topics: Animals; Antineoplastic Agents, Alkylating; Astrocytoma; Blood Glucose; Body Weight; Brain Neoplasms

2012
Fasting enhances the response of glioma to chemo- and radiotherapy.
    PloS one, 2012, Volume: 7, Issue:9

    Topics: Animals; Antineoplastic Agents, Alkylating; Astrocytoma; Blood Glucose; Body Weight; Brain Neoplasms

2012
Decision making and management of gliomas: practical considerations.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2012, Volume: 23 Suppl 10

    Topics: Aged; Astrocytoma; Biomarkers, Tumor; Brain Neoplasms; Dacarbazine; DNA Modification Methylases; DNA

2012
Decision making and management of gliomas: practical considerations.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2012, Volume: 23 Suppl 10

    Topics: Aged; Astrocytoma; Biomarkers, Tumor; Brain Neoplasms; Dacarbazine; DNA Modification Methylases; DNA

2012
Decision making and management of gliomas: practical considerations.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2012, Volume: 23 Suppl 10

    Topics: Aged; Astrocytoma; Biomarkers, Tumor; Brain Neoplasms; Dacarbazine; DNA Modification Methylases; DNA

2012
A review of dose-dense temozolomide alone and in combination with bevacizumab in patients with first relapse of glioblastoma.
    Anticancer research, 2012, Volume: 32, Issue:9

    Topics: Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Brai

2012
A review of dose-dense temozolomide alone and in combination with bevacizumab in patients with first relapse of glioblastoma.
    Anticancer research, 2012, Volume: 32, Issue:9

    Topics: Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Brai

2012
A review of dose-dense temozolomide alone and in combination with bevacizumab in patients with first relapse of glioblastoma.
    Anticancer research, 2012, Volume: 32, Issue:9

    Topics: Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Brai

2012
Survival over 6 years in a patient with brain metastases from melanoma treated with temozolomide.
    BMJ case reports, 2012, Sep-24, Volume: 2012

    Topics: Antineoplastic Agents, Alkylating; Brain; Brain Neoplasms; Dacarbazine; Disease-Free Survival; Femal

2012
Survival over 6 years in a patient with brain metastases from melanoma treated with temozolomide.
    BMJ case reports, 2012, Sep-24, Volume: 2012

    Topics: Antineoplastic Agents, Alkylating; Brain; Brain Neoplasms; Dacarbazine; Disease-Free Survival; Femal

2012
Survival over 6 years in a patient with brain metastases from melanoma treated with temozolomide.
    BMJ case reports, 2012, Sep-24, Volume: 2012

    Topics: Antineoplastic Agents, Alkylating; Brain; Brain Neoplasms; Dacarbazine; Disease-Free Survival; Femal

2012
Prime time for molecular marker diagnostics in neuro-oncology.
    Current opinion in neurology, 2012, Volume: 25, Issue:6

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; DNA Meth

2012
Prime time for molecular marker diagnostics in neuro-oncology.
    Current opinion in neurology, 2012, Volume: 25, Issue:6

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; DNA Meth

2012
Prime time for molecular marker diagnostics in neuro-oncology.
    Current opinion in neurology, 2012, Volume: 25, Issue:6

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; DNA Meth

2012
Efficacy of temozolomide in a central nervous system relapse of neuroblastoma with O 6 -methylguanine methyltransferase (MGMT) promoter methylation.
    Journal of pediatric hematology/oncology, 2013, Volume: 35, Issue:1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Camptothecin; Child, Preschool; Com

2013
Efficacy of temozolomide in a central nervous system relapse of neuroblastoma with O 6 -methylguanine methyltransferase (MGMT) promoter methylation.
    Journal of pediatric hematology/oncology, 2013, Volume: 35, Issue:1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Camptothecin; Child, Preschool; Com

2013
Efficacy of temozolomide in a central nervous system relapse of neuroblastoma with O 6 -methylguanine methyltransferase (MGMT) promoter methylation.
    Journal of pediatric hematology/oncology, 2013, Volume: 35, Issue:1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Camptothecin; Child, Preschool; Com

2013
Disulfiram, a drug widely used to control alcoholism, suppresses the self-renewal of glioblastoma and over-rides resistance to temozolomide.
    Oncotarget, 2012, Volume: 3, Issue:10

    Topics: Alcohol Deterrents; Antineoplastic Agents, Alkylating; Apoptosis; Blotting, Western; Brain Neoplasms

2012
Disulfiram, a drug widely used to control alcoholism, suppresses the self-renewal of glioblastoma and over-rides resistance to temozolomide.
    Oncotarget, 2012, Volume: 3, Issue:10

    Topics: Alcohol Deterrents; Antineoplastic Agents, Alkylating; Apoptosis; Blotting, Western; Brain Neoplasms

2012
Disulfiram, a drug widely used to control alcoholism, suppresses the self-renewal of glioblastoma and over-rides resistance to temozolomide.
    Oncotarget, 2012, Volume: 3, Issue:10

    Topics: Alcohol Deterrents; Antineoplastic Agents, Alkylating; Apoptosis; Blotting, Western; Brain Neoplasms

2012
ATM inhibitor KU-55933 increases the TMZ responsiveness of only inherently TMZ sensitive GBM cells.
    Journal of neuro-oncology, 2012, Volume: 110, Issue:3

    Topics: Animals; Antineoplastic Agents, Alkylating; Apoptosis; Ataxia Telangiectasia Mutated Proteins; Blott

2012
ATM inhibitor KU-55933 increases the TMZ responsiveness of only inherently TMZ sensitive GBM cells.
    Journal of neuro-oncology, 2012, Volume: 110, Issue:3

    Topics: Animals; Antineoplastic Agents, Alkylating; Apoptosis; Ataxia Telangiectasia Mutated Proteins; Blott

2012
ATM inhibitor KU-55933 increases the TMZ responsiveness of only inherently TMZ sensitive GBM cells.
    Journal of neuro-oncology, 2012, Volume: 110, Issue:3

    Topics: Animals; Antineoplastic Agents, Alkylating; Apoptosis; Ataxia Telangiectasia Mutated Proteins; Blott

2012
Failure pattern following complete resection plus radiotherapy and temozolomide is at the resection margin in patients with glioblastoma.
    Journal of neuro-oncology, 2013, Volume: 111, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modalit

2013
Failure pattern following complete resection plus radiotherapy and temozolomide is at the resection margin in patients with glioblastoma.
    Journal of neuro-oncology, 2013, Volume: 111, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modalit

2013
Failure pattern following complete resection plus radiotherapy and temozolomide is at the resection margin in patients with glioblastoma.
    Journal of neuro-oncology, 2013, Volume: 111, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modalit

2013
Mibefradil, a novel therapy for glioblastoma multiforme: cell cycle synchronization and interlaced therapy in a murine model.
    Journal of neuro-oncology, 2013, Volume: 111, Issue:2

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Calcium Channel Blockers; Cell Cycle; D

2013
Mibefradil, a novel therapy for glioblastoma multiforme: cell cycle synchronization and interlaced therapy in a murine model.
    Journal of neuro-oncology, 2013, Volume: 111, Issue:2

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Calcium Channel Blockers; Cell Cycle; D

2013
Mibefradil, a novel therapy for glioblastoma multiforme: cell cycle synchronization and interlaced therapy in a murine model.
    Journal of neuro-oncology, 2013, Volume: 111, Issue:2

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Calcium Channel Blockers; Cell Cycle; D

2013
Increased xCT expression correlates with tumor invasion and outcome in patients with glioblastomas.
    Neurosurgery, 2013, Volume: 72, Issue:1

    Topics: Adult; Age Factors; Aged; Aged, 80 and over; Amino Acid Transport System y+; Antineoplastic Agents,

2013
Increased xCT expression correlates with tumor invasion and outcome in patients with glioblastomas.
    Neurosurgery, 2013, Volume: 72, Issue:1

    Topics: Adult; Age Factors; Aged; Aged, 80 and over; Amino Acid Transport System y+; Antineoplastic Agents,

2013
Increased xCT expression correlates with tumor invasion and outcome in patients with glioblastomas.
    Neurosurgery, 2013, Volume: 72, Issue:1

    Topics: Adult; Age Factors; Aged; Aged, 80 and over; Amino Acid Transport System y+; Antineoplastic Agents,

2013
Rapid desensitization with temozolomide in patients with delayed maculopapular rash.
    Journal of investigational allergology & clinical immunology, 2012, Volume: 22, Issue:6

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Desensitization, Immun

2012
Rapid desensitization with temozolomide in patients with delayed maculopapular rash.
    Journal of investigational allergology & clinical immunology, 2012, Volume: 22, Issue:6

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Desensitization, Immun

2012
Rapid desensitization with temozolomide in patients with delayed maculopapular rash.
    Journal of investigational allergology & clinical immunology, 2012, Volume: 22, Issue:6

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Desensitization, Immun

2012
Relapse of herpes encephalitis induced by temozolomide-based chemoradiation in a patient with malignant glioma.
    Journal of neurosurgery, 2013, Volume: 118, Issue:2

    Topics: Adult; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Dacarbazine; Encephali

2013
Relapse of herpes encephalitis induced by temozolomide-based chemoradiation in a patient with malignant glioma.
    Journal of neurosurgery, 2013, Volume: 118, Issue:2

    Topics: Adult; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Dacarbazine; Encephali

2013
Relapse of herpes encephalitis induced by temozolomide-based chemoradiation in a patient with malignant glioma.
    Journal of neurosurgery, 2013, Volume: 118, Issue:2

    Topics: Adult; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Dacarbazine; Encephali

2013
Sarcomatous evolution of oligodendroglioma ("oligosarcoma"): confirmatory report of an uncommon pattern of malignant progression in oligodendroglial tumors.
    Pathology, research and practice, 2012, Dec-15, Volume: 208, Issue:12

    Topics: Adult; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chromosome Deletion; Chromosomes, Human,

2012
Sarcomatous evolution of oligodendroglioma ("oligosarcoma"): confirmatory report of an uncommon pattern of malignant progression in oligodendroglial tumors.
    Pathology, research and practice, 2012, Dec-15, Volume: 208, Issue:12

    Topics: Adult; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chromosome Deletion; Chromosomes, Human,

2012
Sarcomatous evolution of oligodendroglioma ("oligosarcoma"): confirmatory report of an uncommon pattern of malignant progression in oligodendroglial tumors.
    Pathology, research and practice, 2012, Dec-15, Volume: 208, Issue:12

    Topics: Adult; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chromosome Deletion; Chromosomes, Human,

2012
Overexpression of isocitrate dehydrogenase mutant proteins renders glioma cells more sensitive to radiation.
    Neuro-oncology, 2013, Volume: 15, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Apoptosis; Blotting, Western; Brain Neoplasms; Cell Adhesion; Cel

2013
Overexpression of isocitrate dehydrogenase mutant proteins renders glioma cells more sensitive to radiation.
    Neuro-oncology, 2013, Volume: 15, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Apoptosis; Blotting, Western; Brain Neoplasms; Cell Adhesion; Cel

2013
Overexpression of isocitrate dehydrogenase mutant proteins renders glioma cells more sensitive to radiation.
    Neuro-oncology, 2013, Volume: 15, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Apoptosis; Blotting, Western; Brain Neoplasms; Cell Adhesion; Cel

2013
High levels of phosphorylated MAP kinase are associated with poor survival among patients with glioblastoma during the temozolomide era.
    Neuro-oncology, 2013, Volume: 15, Issue:1

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Daca

2013
High levels of phosphorylated MAP kinase are associated with poor survival among patients with glioblastoma during the temozolomide era.
    Neuro-oncology, 2013, Volume: 15, Issue:1

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Daca

2013
High levels of phosphorylated MAP kinase are associated with poor survival among patients with glioblastoma during the temozolomide era.
    Neuro-oncology, 2013, Volume: 15, Issue:1

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Daca

2013
Detection of glioblastoma response to temozolomide combined with bevacizumab based on μMRI and μPET imaging reveals [18F]-fluoro-L-thymidine as an early and robust predictive marker for treatment efficacy.
    Neuro-oncology, 2013, Volume: 15, Issue:1

    Topics: Animals; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Bevacizu

2013
Detection of glioblastoma response to temozolomide combined with bevacizumab based on μMRI and μPET imaging reveals [18F]-fluoro-L-thymidine as an early and robust predictive marker for treatment efficacy.
    Neuro-oncology, 2013, Volume: 15, Issue:1

    Topics: Animals; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Bevacizu

2013
Detection of glioblastoma response to temozolomide combined with bevacizumab based on μMRI and μPET imaging reveals [18F]-fluoro-L-thymidine as an early and robust predictive marker for treatment efficacy.
    Neuro-oncology, 2013, Volume: 15, Issue:1

    Topics: Animals; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Bevacizu

2013
Bevacizumab-induced oral mucositis in background of cutaneous plaque-type psoriasis.
    The Annals of pharmacotherapy, 2012, Volume: 46, Issue:11

    Topics: Adult; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Antineoplastic Agents, Alkylating

2012
Bevacizumab-induced oral mucositis in background of cutaneous plaque-type psoriasis.
    The Annals of pharmacotherapy, 2012, Volume: 46, Issue:11

    Topics: Adult; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Antineoplastic Agents, Alkylating

2012
Bevacizumab-induced oral mucositis in background of cutaneous plaque-type psoriasis.
    The Annals of pharmacotherapy, 2012, Volume: 46, Issue:11

    Topics: Adult; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Antineoplastic Agents, Alkylating

2012
Targeted nitric oxide delivery preferentially induces glioma cell chemosensitivity via altered p53 and O(6) -methylguanine-DNA methyltransferase activity.
    Biotechnology and bioengineering, 2013, Volume: 110, Issue:4

    Topics: Antineoplastic Agents; Brain Neoplasms; Carmustine; Dacarbazine; Drug Resistance, Neoplasm; Glioblas

2013
Targeted nitric oxide delivery preferentially induces glioma cell chemosensitivity via altered p53 and O(6) -methylguanine-DNA methyltransferase activity.
    Biotechnology and bioengineering, 2013, Volume: 110, Issue:4

    Topics: Antineoplastic Agents; Brain Neoplasms; Carmustine; Dacarbazine; Drug Resistance, Neoplasm; Glioblas

2013
Targeted nitric oxide delivery preferentially induces glioma cell chemosensitivity via altered p53 and O(6) -methylguanine-DNA methyltransferase activity.
    Biotechnology and bioengineering, 2013, Volume: 110, Issue:4

    Topics: Antineoplastic Agents; Brain Neoplasms; Carmustine; Dacarbazine; Drug Resistance, Neoplasm; Glioblas

2013
Knockdown of Nrf2 enhances autophagy induced by temozolomide in U251 human glioma cell line.
    Oncology reports, 2013, Volume: 29, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Apoptosis; Autophagy; Blotting, Western; Brain Neoplasms; Dacarba

2013
Knockdown of Nrf2 enhances autophagy induced by temozolomide in U251 human glioma cell line.
    Oncology reports, 2013, Volume: 29, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Apoptosis; Autophagy; Blotting, Western; Brain Neoplasms; Dacarba

2013
Knockdown of Nrf2 enhances autophagy induced by temozolomide in U251 human glioma cell line.
    Oncology reports, 2013, Volume: 29, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Apoptosis; Autophagy; Blotting, Western; Brain Neoplasms; Dacarba

2013
Hypofractionated stereotactic radiotherapy and continuous low-dose temozolomide in patients with recurrent or progressive malignant gliomas.
    Journal of neuro-oncology, 2013, Volume: 111, Issue:2

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Dihydroxyphenylalanine

2013
Hypofractionated stereotactic radiotherapy and continuous low-dose temozolomide in patients with recurrent or progressive malignant gliomas.
    Journal of neuro-oncology, 2013, Volume: 111, Issue:2

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Dihydroxyphenylalanine

2013
Hypofractionated stereotactic radiotherapy and continuous low-dose temozolomide in patients with recurrent or progressive malignant gliomas.
    Journal of neuro-oncology, 2013, Volume: 111, Issue:2

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Dihydroxyphenylalanine

2013
Aldehyde dehydrogenase 1A1--a new mediator of resistance to temozolomide in glioblastoma.
    Neuro-oncology, 2012, Volume: 14, Issue:12

    Topics: Aged; Aldehyde Dehydrogenase; Aldehyde Dehydrogenase 1 Family; Antineoplastic Agents; Biomarkers, Tu

2012
Aldehyde dehydrogenase 1A1--a new mediator of resistance to temozolomide in glioblastoma.
    Neuro-oncology, 2012, Volume: 14, Issue:12

    Topics: Aged; Aldehyde Dehydrogenase; Aldehyde Dehydrogenase 1 Family; Antineoplastic Agents; Biomarkers, Tu

2012
Aldehyde dehydrogenase 1A1--a new mediator of resistance to temozolomide in glioblastoma.
    Neuro-oncology, 2012, Volume: 14, Issue:12

    Topics: Aged; Aldehyde Dehydrogenase; Aldehyde Dehydrogenase 1 Family; Antineoplastic Agents; Biomarkers, Tu

2012
Effective elimination of cancer stem cells by a novel drug combination strategy.
    Stem cells (Dayton, Ohio), 2013, Volume: 31, Issue:1

    Topics: Adenosine Triphosphate; Animals; Brain Neoplasms; Carmustine; Cell Line, Tumor; Cell Survival; Dacar

2013
Effective elimination of cancer stem cells by a novel drug combination strategy.
    Stem cells (Dayton, Ohio), 2013, Volume: 31, Issue:1

    Topics: Adenosine Triphosphate; Animals; Brain Neoplasms; Carmustine; Cell Line, Tumor; Cell Survival; Dacar

2013
Effective elimination of cancer stem cells by a novel drug combination strategy.
    Stem cells (Dayton, Ohio), 2013, Volume: 31, Issue:1

    Topics: Adenosine Triphosphate; Animals; Brain Neoplasms; Carmustine; Cell Line, Tumor; Cell Survival; Dacar

2013
Neuro-oncology: treatment decisions in elderly patients with glioblastoma.
    Nature reviews. Neurology, 2012, Volume: 8, Issue:12

    Topics: Aged; Antineoplastic Agents; Brain Neoplasms; Chemoradiotherapy; Dacarbazine; Glioblastoma; Humans;

2012
Neuro-oncology: treatment decisions in elderly patients with glioblastoma.
    Nature reviews. Neurology, 2012, Volume: 8, Issue:12

    Topics: Aged; Antineoplastic Agents; Brain Neoplasms; Chemoradiotherapy; Dacarbazine; Glioblastoma; Humans;

2012
Neuro-oncology: treatment decisions in elderly patients with glioblastoma.
    Nature reviews. Neurology, 2012, Volume: 8, Issue:12

    Topics: Aged; Antineoplastic Agents; Brain Neoplasms; Chemoradiotherapy; Dacarbazine; Glioblastoma; Humans;

2012
An efficient and practical radiosynthesis of [11C]temozolomide.
    Organic letters, 2012, Dec-07, Volume: 14, Issue:23

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Carbon Radioisotopes; Dacarbazine; Molecular Str

2012
An efficient and practical radiosynthesis of [11C]temozolomide.
    Organic letters, 2012, Dec-07, Volume: 14, Issue:23

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Carbon Radioisotopes; Dacarbazine; Molecular Str

2012
An efficient and practical radiosynthesis of [11C]temozolomide.
    Organic letters, 2012, Dec-07, Volume: 14, Issue:23

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Carbon Radioisotopes; Dacarbazine; Molecular Str

2012
Equinatoxin II potentiates temozolomide- and etoposide-induced glioblastoma cell death.
    Current topics in medicinal chemistry, 2012, Volume: 12, Issue:19

    Topics: Animals; Antineoplastic Agents; Apoptosis; Blotting, Western; Brain Neoplasms; Cell Line, Tumor; Cni

2012
Equinatoxin II potentiates temozolomide- and etoposide-induced glioblastoma cell death.
    Current topics in medicinal chemistry, 2012, Volume: 12, Issue:19

    Topics: Animals; Antineoplastic Agents; Apoptosis; Blotting, Western; Brain Neoplasms; Cell Line, Tumor; Cni

2012
Equinatoxin II potentiates temozolomide- and etoposide-induced glioblastoma cell death.
    Current topics in medicinal chemistry, 2012, Volume: 12, Issue:19

    Topics: Animals; Antineoplastic Agents; Apoptosis; Blotting, Western; Brain Neoplasms; Cell Line, Tumor; Cni

2012
Multimodal magnetic resonance imaging and 18F-L-dihydroxyphenylalanine positron emission tomography in early characterization of pseudoresponse and nonenhancing tumor progression in a pediatric patient with malignant transformation of ganglioglioma treate
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2013, Jan-01, Volume: 31, Issue:1

    Topics: Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Brai

2013
Multimodal magnetic resonance imaging and 18F-L-dihydroxyphenylalanine positron emission tomography in early characterization of pseudoresponse and nonenhancing tumor progression in a pediatric patient with malignant transformation of ganglioglioma treate
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2013, Jan-01, Volume: 31, Issue:1

    Topics: Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Brai

2013
Multimodal magnetic resonance imaging and 18F-L-dihydroxyphenylalanine positron emission tomography in early characterization of pseudoresponse and nonenhancing tumor progression in a pediatric patient with malignant transformation of ganglioglioma treate
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2013, Jan-01, Volume: 31, Issue:1

    Topics: Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Brai

2013
Immunohistochemical molecular gene expression profile of metastatic brain tumor as a potent personalized medicine.
    Brain tumor pathology, 2013, Volume: 30, Issue:3

    Topics: Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain; Brain Neoplasms; Dacarbazine; DNA

2013
Immunohistochemical molecular gene expression profile of metastatic brain tumor as a potent personalized medicine.
    Brain tumor pathology, 2013, Volume: 30, Issue:3

    Topics: Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain; Brain Neoplasms; Dacarbazine; DNA

2013
Immunohistochemical molecular gene expression profile of metastatic brain tumor as a potent personalized medicine.
    Brain tumor pathology, 2013, Volume: 30, Issue:3

    Topics: Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain; Brain Neoplasms; Dacarbazine; DNA

2013
Mutant TP53 enhances the resistance of glioblastoma cells to temozolomide by up-regulating O(6)-methylguanine DNA-methyltransferase.
    Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 2013, Volume: 34, Issue:8

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Dacarbazine; Drug Resistance,

2013
Mutant TP53 enhances the resistance of glioblastoma cells to temozolomide by up-regulating O(6)-methylguanine DNA-methyltransferase.
    Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 2013, Volume: 34, Issue:8

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Dacarbazine; Drug Resistance,

2013
Mutant TP53 enhances the resistance of glioblastoma cells to temozolomide by up-regulating O(6)-methylguanine DNA-methyltransferase.
    Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 2013, Volume: 34, Issue:8

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Dacarbazine; Drug Resistance,

2013
Combination of paclitaxel thermal gel depot with temozolomide and radiotherapy significantly prolongs survival in an experimental rodent glioma model.
    Journal of neuro-oncology, 2013, Volume: 111, Issue:3

    Topics: Analysis of Variance; Animals; Antineoplastic Agents, Phytogenic; Brain Neoplasms; Dacarbazine; Dise

2013
Combination of paclitaxel thermal gel depot with temozolomide and radiotherapy significantly prolongs survival in an experimental rodent glioma model.
    Journal of neuro-oncology, 2013, Volume: 111, Issue:3

    Topics: Analysis of Variance; Animals; Antineoplastic Agents, Phytogenic; Brain Neoplasms; Dacarbazine; Dise

2013
Combination of paclitaxel thermal gel depot with temozolomide and radiotherapy significantly prolongs survival in an experimental rodent glioma model.
    Journal of neuro-oncology, 2013, Volume: 111, Issue:3

    Topics: Analysis of Variance; Animals; Antineoplastic Agents, Phytogenic; Brain Neoplasms; Dacarbazine; Dise

2013
Distance to the neurooncological center: a negative prognostic factor in patients with glioblastoma multiforme. An epidemiological study.
    Anticancer research, 2012, Volume: 32, Issue:12

    Topics: Adult; Aged; Aged, 80 and over; Brain Neoplasms; Chemotherapy, Adjuvant; Cohort Studies; Dacarbazine

2012
Distance to the neurooncological center: a negative prognostic factor in patients with glioblastoma multiforme. An epidemiological study.
    Anticancer research, 2012, Volume: 32, Issue:12

    Topics: Adult; Aged; Aged, 80 and over; Brain Neoplasms; Chemotherapy, Adjuvant; Cohort Studies; Dacarbazine

2012
Distance to the neurooncological center: a negative prognostic factor in patients with glioblastoma multiforme. An epidemiological study.
    Anticancer research, 2012, Volume: 32, Issue:12

    Topics: Adult; Aged; Aged, 80 and over; Brain Neoplasms; Chemotherapy, Adjuvant; Cohort Studies; Dacarbazine

2012
Malignant glioma with angiocentric features.
    Journal of neurosurgery. Pediatrics, 2013, Volume: 11, Issue:3

    Topics: Adolescent; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazi

2013
Malignant glioma with angiocentric features.
    Journal of neurosurgery. Pediatrics, 2013, Volume: 11, Issue:3

    Topics: Adolescent; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazi

2013
Malignant glioma with angiocentric features.
    Journal of neurosurgery. Pediatrics, 2013, Volume: 11, Issue:3

    Topics: Adolescent; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazi

2013
Pharmacologic blockade of FAK autophosphorylation decreases human glioblastoma tumor growth and synergizes with temozolomide.
    Molecular cancer therapeutics, 2013, Volume: 12, Issue:2

    Topics: Animals; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Apoptosi

2013
Pharmacologic blockade of FAK autophosphorylation decreases human glioblastoma tumor growth and synergizes with temozolomide.
    Molecular cancer therapeutics, 2013, Volume: 12, Issue:2

    Topics: Animals; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Apoptosi

2013
Pharmacologic blockade of FAK autophosphorylation decreases human glioblastoma tumor growth and synergizes with temozolomide.
    Molecular cancer therapeutics, 2013, Volume: 12, Issue:2

    Topics: Animals; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Apoptosi

2013
MGMT promoter methylation status and MGMT and CD133 immunohistochemical expression as prognostic markers in glioblastoma patients treated with temozolomide plus radiotherapy.
    Journal of translational medicine, 2012, Dec-17, Volume: 10

    Topics: AC133 Antigen; Adult; Aged; Aged, 80 and over; Antigens, CD; Biomarkers, Tumor; Brain Neoplasms; Dac

2012
MGMT promoter methylation status and MGMT and CD133 immunohistochemical expression as prognostic markers in glioblastoma patients treated with temozolomide plus radiotherapy.
    Journal of translational medicine, 2012, Dec-17, Volume: 10

    Topics: AC133 Antigen; Adult; Aged; Aged, 80 and over; Antigens, CD; Biomarkers, Tumor; Brain Neoplasms; Dac

2012
MGMT promoter methylation status and MGMT and CD133 immunohistochemical expression as prognostic markers in glioblastoma patients treated with temozolomide plus radiotherapy.
    Journal of translational medicine, 2012, Dec-17, Volume: 10

    Topics: AC133 Antigen; Adult; Aged; Aged, 80 and over; Antigens, CD; Biomarkers, Tumor; Brain Neoplasms; Dac

2012
Inhibition of GSH synthesis potentiates temozolomide-induced bystander effect in glioblastoma.
    Cancer letters, 2013, Apr-30, Volume: 331, Issue:1

    Topics: Animals; Antineoplastic Agents, Alkylating; Apoptosis; Blotting, Western; Brain Neoplasms; Bystander

2013
Inhibition of GSH synthesis potentiates temozolomide-induced bystander effect in glioblastoma.
    Cancer letters, 2013, Apr-30, Volume: 331, Issue:1

    Topics: Animals; Antineoplastic Agents, Alkylating; Apoptosis; Blotting, Western; Brain Neoplasms; Bystander

2013
Inhibition of GSH synthesis potentiates temozolomide-induced bystander effect in glioblastoma.
    Cancer letters, 2013, Apr-30, Volume: 331, Issue:1

    Topics: Animals; Antineoplastic Agents, Alkylating; Apoptosis; Blotting, Western; Brain Neoplasms; Bystander

2013
DARPP32, STAT5 and STAT3 mRNA expression ratios in glioblastomas are associated with patient outcome.
    Pathology oncology research : POR, 2013, Volume: 19, Issue:2

    Topics: Apoptosis; Brain Neoplasms; Dacarbazine; Dopamine and cAMP-Regulated Phosphoprotein 32; Female; Glio

2013
DARPP32, STAT5 and STAT3 mRNA expression ratios in glioblastomas are associated with patient outcome.
    Pathology oncology research : POR, 2013, Volume: 19, Issue:2

    Topics: Apoptosis; Brain Neoplasms; Dacarbazine; Dopamine and cAMP-Regulated Phosphoprotein 32; Female; Glio

2013
DARPP32, STAT5 and STAT3 mRNA expression ratios in glioblastomas are associated with patient outcome.
    Pathology oncology research : POR, 2013, Volume: 19, Issue:2

    Topics: Apoptosis; Brain Neoplasms; Dacarbazine; Dopamine and cAMP-Regulated Phosphoprotein 32; Female; Glio

2013
Toxicity and survival in primary glioblastoma patients treated with concomitant plus adjuvant temozolomide versus adjuvant temozolomide: results of a single-institution, retrospective, matched-pair analysis.
    Acta neurochirurgica, 2013, Volume: 155, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherap

2013
Toxicity and survival in primary glioblastoma patients treated with concomitant plus adjuvant temozolomide versus adjuvant temozolomide: results of a single-institution, retrospective, matched-pair analysis.
    Acta neurochirurgica, 2013, Volume: 155, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherap

2013
Toxicity and survival in primary glioblastoma patients treated with concomitant plus adjuvant temozolomide versus adjuvant temozolomide: results of a single-institution, retrospective, matched-pair analysis.
    Acta neurochirurgica, 2013, Volume: 155, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherap

2013
The DNA repair protein ALKBH2 mediates temozolomide resistance in human glioblastoma cells.
    Neuro-oncology, 2013, Volume: 15, Issue:3

    Topics: AlkB Homolog 2, Alpha-Ketoglutarate-Dependent Dioxygenase; Antineoplastic Agents, Alkylating; Blotti

2013
The DNA repair protein ALKBH2 mediates temozolomide resistance in human glioblastoma cells.
    Neuro-oncology, 2013, Volume: 15, Issue:3

    Topics: AlkB Homolog 2, Alpha-Ketoglutarate-Dependent Dioxygenase; Antineoplastic Agents, Alkylating; Blotti

2013
The DNA repair protein ALKBH2 mediates temozolomide resistance in human glioblastoma cells.
    Neuro-oncology, 2013, Volume: 15, Issue:3

    Topics: AlkB Homolog 2, Alpha-Ketoglutarate-Dependent Dioxygenase; Antineoplastic Agents, Alkylating; Blotti

2013
Temozolomide use in adult patients with gliosarcoma: an evolving clinical practice.
    Journal of neuro-oncology, 2013, Volume: 112, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Fem

2013
Temozolomide use in adult patients with gliosarcoma: an evolving clinical practice.
    Journal of neuro-oncology, 2013, Volume: 112, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Fem

2013
Temozolomide use in adult patients with gliosarcoma: an evolving clinical practice.
    Journal of neuro-oncology, 2013, Volume: 112, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Fem

2013
Subcellular real-time imaging of the efficacy of temozolomide on cancer cells in the brain of live mice.
    Anticancer research, 2013, Volume: 33, Issue:1

    Topics: Animals; Apoptosis; Brain Neoplasms; Carcinoma, Lewis Lung; Cell Line, Tumor; Cell Nucleus; Cranioto

2013
Subcellular real-time imaging of the efficacy of temozolomide on cancer cells in the brain of live mice.
    Anticancer research, 2013, Volume: 33, Issue:1

    Topics: Animals; Apoptosis; Brain Neoplasms; Carcinoma, Lewis Lung; Cell Line, Tumor; Cell Nucleus; Cranioto

2013
Subcellular real-time imaging of the efficacy of temozolomide on cancer cells in the brain of live mice.
    Anticancer research, 2013, Volume: 33, Issue:1

    Topics: Animals; Apoptosis; Brain Neoplasms; Carcinoma, Lewis Lung; Cell Line, Tumor; Cell Nucleus; Cranioto

2013
Quantitative probabilistic functional diffusion mapping in newly diagnosed glioblastoma treated with radiochemotherapy.
    Neuro-oncology, 2013, Volume: 15, Issue:3

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Dacarbazine; Diffusion Magnet

2013
Quantitative probabilistic functional diffusion mapping in newly diagnosed glioblastoma treated with radiochemotherapy.
    Neuro-oncology, 2013, Volume: 15, Issue:3

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Dacarbazine; Diffusion Magnet

2013
Quantitative probabilistic functional diffusion mapping in newly diagnosed glioblastoma treated with radiochemotherapy.
    Neuro-oncology, 2013, Volume: 15, Issue:3

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Dacarbazine; Diffusion Magnet

2013
Integration method of 3D MR spectroscopy into treatment planning system for glioblastoma IMRT dose painting with integrated simultaneous boost.
    Radiation oncology (London, England), 2013, Jan-02, Volume: 8

    Topics: Brain Neoplasms; Contrast Media; Dacarbazine; Glioblastoma; Humans; Image Processing, Computer-Assis

2013
Integration method of 3D MR spectroscopy into treatment planning system for glioblastoma IMRT dose painting with integrated simultaneous boost.
    Radiation oncology (London, England), 2013, Jan-02, Volume: 8

    Topics: Brain Neoplasms; Contrast Media; Dacarbazine; Glioblastoma; Humans; Image Processing, Computer-Assis

2013
Integration method of 3D MR spectroscopy into treatment planning system for glioblastoma IMRT dose painting with integrated simultaneous boost.
    Radiation oncology (London, England), 2013, Jan-02, Volume: 8

    Topics: Brain Neoplasms; Contrast Media; Dacarbazine; Glioblastoma; Humans; Image Processing, Computer-Assis

2013
Exclusion of histiocytes/endothelial cells and using endothelial cells as internal reference are crucial for interpretation of MGMT immunohistochemistry in glioblastoma.
    The American journal of surgical pathology, 2013, Volume: 37, Issue:2

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Biomarkers, Tumor; Br

2013
Exclusion of histiocytes/endothelial cells and using endothelial cells as internal reference are crucial for interpretation of MGMT immunohistochemistry in glioblastoma.
    The American journal of surgical pathology, 2013, Volume: 37, Issue:2

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Biomarkers, Tumor; Br

2013
Exclusion of histiocytes/endothelial cells and using endothelial cells as internal reference are crucial for interpretation of MGMT immunohistochemistry in glioblastoma.
    The American journal of surgical pathology, 2013, Volume: 37, Issue:2

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Biomarkers, Tumor; Br

2013
Impact of temozolomide on gonadal function in patients with primary malignant brain tumors.
    Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners, 2013, Volume: 19, Issue:4

    Topics: Adult; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; F

2013
Impact of temozolomide on gonadal function in patients with primary malignant brain tumors.
    Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners, 2013, Volume: 19, Issue:4

    Topics: Adult; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; F

2013
Impact of temozolomide on gonadal function in patients with primary malignant brain tumors.
    Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners, 2013, Volume: 19, Issue:4

    Topics: Adult; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; F

2013
Response to bevacizumab, irinotecan, and temozolomide in children with relapsed medulloblastoma: a multi-institutional experience.
    Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 2013, Volume: 29, Issue:4

    Topics: Adolescent; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Bevac

2013
Response to bevacizumab, irinotecan, and temozolomide in children with relapsed medulloblastoma: a multi-institutional experience.
    Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 2013, Volume: 29, Issue:4

    Topics: Adolescent; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Bevac

2013
Response to bevacizumab, irinotecan, and temozolomide in children with relapsed medulloblastoma: a multi-institutional experience.
    Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 2013, Volume: 29, Issue:4

    Topics: Adolescent; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Bevac

2013
Tetra-O-methyl nordihydroguaiaretic acid, an inhibitor of Sp1-mediated survivin transcription, induces apoptosis and acts synergistically with chemo-radiotherapy in glioblastoma cells.
    Investigational new drugs, 2013, Volume: 31, Issue:4

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Brain Neoplasms; Cell Cycle; Cell

2013
Tetra-O-methyl nordihydroguaiaretic acid, an inhibitor of Sp1-mediated survivin transcription, induces apoptosis and acts synergistically with chemo-radiotherapy in glioblastoma cells.
    Investigational new drugs, 2013, Volume: 31, Issue:4

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Brain Neoplasms; Cell Cycle; Cell

2013
Tetra-O-methyl nordihydroguaiaretic acid, an inhibitor of Sp1-mediated survivin transcription, induces apoptosis and acts synergistically with chemo-radiotherapy in glioblastoma cells.
    Investigational new drugs, 2013, Volume: 31, Issue:4

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Brain Neoplasms; Cell Cycle; Cell

2013
Performance status during and after radiotherapy plus concomitant and adjuvant temozolomide in elderly patients with glioblastoma multiforme.
    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2013, Volume: 20, Issue:4

    Topics: Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy, Adjuvant; Dacarbazine;

2013
Performance status during and after radiotherapy plus concomitant and adjuvant temozolomide in elderly patients with glioblastoma multiforme.
    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2013, Volume: 20, Issue:4

    Topics: Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy, Adjuvant; Dacarbazine;

2013
Performance status during and after radiotherapy plus concomitant and adjuvant temozolomide in elderly patients with glioblastoma multiforme.
    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2013, Volume: 20, Issue:4

    Topics: Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy, Adjuvant; Dacarbazine;

2013
Engineered drug resistant γδ T cells kill glioblastoma cell lines during a chemotherapy challenge: a strategy for combining chemo- and immunotherapy.
    PloS one, 2013, Volume: 8, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Cell Survival; Cells, Cultured

2013
Engineered drug resistant γδ T cells kill glioblastoma cell lines during a chemotherapy challenge: a strategy for combining chemo- and immunotherapy.
    PloS one, 2013, Volume: 8, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Cell Survival; Cells, Cultured

2013
Engineered drug resistant γδ T cells kill glioblastoma cell lines during a chemotherapy challenge: a strategy for combining chemo- and immunotherapy.
    PloS one, 2013, Volume: 8, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Cell Survival; Cells, Cultured

2013
Combined analysis of O6-methylguanine-DNA methyltransferase protein expression and promoter methylation provides optimized prognostication of glioblastoma outcome.
    Neuro-oncology, 2013, Volume: 15, Issue:3

    Topics: Adult; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Dacarbazine; DNA Methy

2013
Combined analysis of O6-methylguanine-DNA methyltransferase protein expression and promoter methylation provides optimized prognostication of glioblastoma outcome.
    Neuro-oncology, 2013, Volume: 15, Issue:3

    Topics: Adult; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Dacarbazine; DNA Methy

2013
Combined analysis of O6-methylguanine-DNA methyltransferase protein expression and promoter methylation provides optimized prognostication of glioblastoma outcome.
    Neuro-oncology, 2013, Volume: 15, Issue:3

    Topics: Adult; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Dacarbazine; DNA Methy

2013
Downregulation of Src enhances the cytotoxic effect of temozolomide through AKT in glioma.
    Oncology reports, 2013, Volume: 29, Issue:4

    Topics: Animals; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Dacarbazine; Down-Regulation; Gene Expression

2013
Downregulation of Src enhances the cytotoxic effect of temozolomide through AKT in glioma.
    Oncology reports, 2013, Volume: 29, Issue:4

    Topics: Animals; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Dacarbazine; Down-Regulation; Gene Expression

2013
Downregulation of Src enhances the cytotoxic effect of temozolomide through AKT in glioma.
    Oncology reports, 2013, Volume: 29, Issue:4

    Topics: Animals; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Dacarbazine; Down-Regulation; Gene Expression

2013
In human glioblastomas transcript elongation by alternative polyadenylation and miRNA targeting is a potent mechanism of MGMT silencing.
    Acta neuropathologica, 2013, Volume: 125, Issue:5

    Topics: 3' Untranslated Regions; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Culture Techniques

2013
In human glioblastomas transcript elongation by alternative polyadenylation and miRNA targeting is a potent mechanism of MGMT silencing.
    Acta neuropathologica, 2013, Volume: 125, Issue:5

    Topics: 3' Untranslated Regions; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Culture Techniques

2013
In human glioblastomas transcript elongation by alternative polyadenylation and miRNA targeting is a potent mechanism of MGMT silencing.
    Acta neuropathologica, 2013, Volume: 125, Issue:5

    Topics: 3' Untranslated Regions; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Culture Techniques

2013
Anti-tumour efficacy on glioma models of PHA-848125, a multi-kinase inhibitor able to cross the blood-brain barrier.
    British journal of pharmacology, 2013, Volume: 169, Issue:1

    Topics: Animals; Antineoplastic Agents; Blood-Brain Barrier; Brain Neoplasms; Cell Line, Tumor; Cell Prolife

2013
Anti-tumour efficacy on glioma models of PHA-848125, a multi-kinase inhibitor able to cross the blood-brain barrier.
    British journal of pharmacology, 2013, Volume: 169, Issue:1

    Topics: Animals; Antineoplastic Agents; Blood-Brain Barrier; Brain Neoplasms; Cell Line, Tumor; Cell Prolife

2013
Anti-tumour efficacy on glioma models of PHA-848125, a multi-kinase inhibitor able to cross the blood-brain barrier.
    British journal of pharmacology, 2013, Volume: 169, Issue:1

    Topics: Animals; Antineoplastic Agents; Blood-Brain Barrier; Brain Neoplasms; Cell Line, Tumor; Cell Prolife

2013
Predictive significance of mean apparent diffusion coefficient value for responsiveness of temozolomide-refractory malignant glioma to bevacizumab: preliminary report.
    International journal of clinical oncology, 2014, Volume: 19, Issue:1

    Topics: Adult; Aged; Antibodies, Monoclonal, Humanized; Bevacizumab; Brain Neoplasms; Dacarbazine; Disease-F

2014
Predictive significance of mean apparent diffusion coefficient value for responsiveness of temozolomide-refractory malignant glioma to bevacizumab: preliminary report.
    International journal of clinical oncology, 2014, Volume: 19, Issue:1

    Topics: Adult; Aged; Antibodies, Monoclonal, Humanized; Bevacizumab; Brain Neoplasms; Dacarbazine; Disease-F

2014
Predictive significance of mean apparent diffusion coefficient value for responsiveness of temozolomide-refractory malignant glioma to bevacizumab: preliminary report.
    International journal of clinical oncology, 2014, Volume: 19, Issue:1

    Topics: Adult; Aged; Antibodies, Monoclonal, Humanized; Bevacizumab; Brain Neoplasms; Dacarbazine; Disease-F

2014
The value of temozolomide in combination with radiotherapy during standard treatment for newly diagnosed glioblastoma.
    Journal of neuro-oncology, 2013, Volume: 112, Issue:2

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Chemotherapy, Ad

2013
The value of temozolomide in combination with radiotherapy during standard treatment for newly diagnosed glioblastoma.
    Journal of neuro-oncology, 2013, Volume: 112, Issue:2

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Chemotherapy, Ad

2013
The value of temozolomide in combination with radiotherapy during standard treatment for newly diagnosed glioblastoma.
    Journal of neuro-oncology, 2013, Volume: 112, Issue:2

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Chemotherapy, Ad

2013
Patterns of relapse in glioblastoma multiforme following concomitant chemoradiotherapy with temozolomide.
    The British journal of radiology, 2013, Volume: 86, Issue:1022

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Daca

2013
Patterns of relapse in glioblastoma multiforme following concomitant chemoradiotherapy with temozolomide.
    The British journal of radiology, 2013, Volume: 86, Issue:1022

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Daca

2013
Patterns of relapse in glioblastoma multiforme following concomitant chemoradiotherapy with temozolomide.
    The British journal of radiology, 2013, Volume: 86, Issue:1022

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Daca

2013
Breast metastasis of anaplastic oligodendroglioma: a case report.
    Tumori, 2012, Volume: 98, Issue:6

    Topics: Antineoplastic Agents, Alkylating; Aphasia; Brain Neoplasms; Breast Neoplasms, Male; Chemoradiothera

2012
Breast metastasis of anaplastic oligodendroglioma: a case report.
    Tumori, 2012, Volume: 98, Issue:6

    Topics: Antineoplastic Agents, Alkylating; Aphasia; Brain Neoplasms; Breast Neoplasms, Male; Chemoradiothera

2012
Breast metastasis of anaplastic oligodendroglioma: a case report.
    Tumori, 2012, Volume: 98, Issue:6

    Topics: Antineoplastic Agents, Alkylating; Aphasia; Brain Neoplasms; Breast Neoplasms, Male; Chemoradiothera

2012
Hypernatremia-associated myelinolysis following the management of sepsis in a patient with glioblastoma treated with radiotherapy and temozolomide.
    Acta neurologica Belgica, 2013, Volume: 113, Issue:4

    Topics: Antineoplastic Agents; Brain Diseases; Brain Neoplasms; Carcinoma; Carcinoma, Papillary; Dacarbazine

2013
Hypernatremia-associated myelinolysis following the management of sepsis in a patient with glioblastoma treated with radiotherapy and temozolomide.
    Acta neurologica Belgica, 2013, Volume: 113, Issue:4

    Topics: Antineoplastic Agents; Brain Diseases; Brain Neoplasms; Carcinoma; Carcinoma, Papillary; Dacarbazine

2013
Hypernatremia-associated myelinolysis following the management of sepsis in a patient with glioblastoma treated with radiotherapy and temozolomide.
    Acta neurologica Belgica, 2013, Volume: 113, Issue:4

    Topics: Antineoplastic Agents; Brain Diseases; Brain Neoplasms; Carcinoma; Carcinoma, Papillary; Dacarbazine

2013
Using susceptibility-weighted imaging to determine response to combined anti-angiogenic, cytotoxic, and radiation therapy in patients with glioblastoma multiforme.
    Neuro-oncology, 2013, Volume: 15, Issue:4

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Chemoradiotherapy; Dac

2013
Using susceptibility-weighted imaging to determine response to combined anti-angiogenic, cytotoxic, and radiation therapy in patients with glioblastoma multiforme.
    Neuro-oncology, 2013, Volume: 15, Issue:4

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Chemoradiotherapy; Dac

2013
Using susceptibility-weighted imaging to determine response to combined anti-angiogenic, cytotoxic, and radiation therapy in patients with glioblastoma multiforme.
    Neuro-oncology, 2013, Volume: 15, Issue:4

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Chemoradiotherapy; Dac

2013
Temozolomide as second-line chemotherapy for relapsed gliomas.
    Journal of neuro-oncology, 2002, Volume: 57, Issue:3

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Female; Glioma; Humans

2002
Temozolomide as second-line chemotherapy for relapsed gliomas.
    Journal of neuro-oncology, 2002, Volume: 57, Issue:3

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Female; Glioma; Humans

2002
Temozolomide as second-line chemotherapy for relapsed gliomas.
    Journal of neuro-oncology, 2002, Volume: 57, Issue:3

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Female; Glioma; Humans

2002
Multifaceted resistance of gliomas to temozolomide.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2002, Volume: 8, Issue:8

    Topics: Alleles; Animals; Antineoplastic Agents, Alkylating; Apoptosis; Base Pair Mismatch; Blotting, Wester

2002
Multifaceted resistance of gliomas to temozolomide.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2002, Volume: 8, Issue:8

    Topics: Alleles; Animals; Antineoplastic Agents, Alkylating; Apoptosis; Base Pair Mismatch; Blotting, Wester

2002
Multifaceted resistance of gliomas to temozolomide.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2002, Volume: 8, Issue:8

    Topics: Alleles; Animals; Antineoplastic Agents, Alkylating; Apoptosis; Base Pair Mismatch; Blotting, Wester

2002
The apurinic/apyrimidinic endonuclease activity of Ape1/Ref-1 contributes to human glioma cell resistance to alkylating agents and is elevated by oxidative stress.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2002, Volume: 8, Issue:9

    Topics: Antineoplastic Agents, Alkylating; Apurinic Acid; Brain Neoplasms; Carbon-Oxygen Lyases; Carmustine;

2002
The apurinic/apyrimidinic endonuclease activity of Ape1/Ref-1 contributes to human glioma cell resistance to alkylating agents and is elevated by oxidative stress.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2002, Volume: 8, Issue:9

    Topics: Antineoplastic Agents, Alkylating; Apurinic Acid; Brain Neoplasms; Carbon-Oxygen Lyases; Carmustine;

2002
The apurinic/apyrimidinic endonuclease activity of Ape1/Ref-1 contributes to human glioma cell resistance to alkylating agents and is elevated by oxidative stress.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2002, Volume: 8, Issue:9

    Topics: Antineoplastic Agents, Alkylating; Apurinic Acid; Brain Neoplasms; Carbon-Oxygen Lyases; Carmustine;

2002
Poly(ADP-ribose) polymerase inhibitor increases growth inhibition and reduces G(2)/M cell accumulation induced by temozolomide in malignant glioma cells.
    Glia, 2002, Volume: 40, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Benzamides; Brain

2002
Poly(ADP-ribose) polymerase inhibitor increases growth inhibition and reduces G(2)/M cell accumulation induced by temozolomide in malignant glioma cells.
    Glia, 2002, Volume: 40, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Benzamides; Brain

2002
Poly(ADP-ribose) polymerase inhibitor increases growth inhibition and reduces G(2)/M cell accumulation induced by temozolomide in malignant glioma cells.
    Glia, 2002, Volume: 40, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Benzamides; Brain

2002
Case report: a patient with primary CNS lymphoma treated with temozolomide to complete response.
    Journal of neuro-oncology, 2002, Volume: 59, Issue:2

    Topics: Administration, Oral; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Female;

2002
Case report: a patient with primary CNS lymphoma treated with temozolomide to complete response.
    Journal of neuro-oncology, 2002, Volume: 59, Issue:2

    Topics: Administration, Oral; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Female;

2002
Case report: a patient with primary CNS lymphoma treated with temozolomide to complete response.
    Journal of neuro-oncology, 2002, Volume: 59, Issue:2

    Topics: Administration, Oral; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Female;

2002
[Temozolomide as therapeutic option for patients with metastatic melanoma and poor prognosis].
    Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete, 2002, Volume: 53, Issue:10

    Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neopl

2002
[Temozolomide as therapeutic option for patients with metastatic melanoma and poor prognosis].
    Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete, 2002, Volume: 53, Issue:10

    Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neopl

2002
[Temozolomide as therapeutic option for patients with metastatic melanoma and poor prognosis].
    Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete, 2002, Volume: 53, Issue:10

    Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neopl

2002
Hemorrhagic cystitis as an unexpected adverse reaction to temozolomide: case report.
    American journal of clinical oncology, 2002, Volume: 25, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Breast Neoplasms; Cystitis; Dacarbazine; Female;

2002
Hemorrhagic cystitis as an unexpected adverse reaction to temozolomide: case report.
    American journal of clinical oncology, 2002, Volume: 25, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Breast Neoplasms; Cystitis; Dacarbazine; Female;

2002
Hemorrhagic cystitis as an unexpected adverse reaction to temozolomide: case report.
    American journal of clinical oncology, 2002, Volume: 25, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Breast Neoplasms; Cystitis; Dacarbazine; Female;

2002
[Treatment of anaplastic astrocytomas and glioblastomas in children by the use of temozolomide (TMZ)].
    Voprosy onkologii, 2002, Volume: 48, Issue:3

    Topics: Adolescent; Adult; Age Factors; Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neoplasms; Bra

2002
[Treatment of anaplastic astrocytomas and glioblastomas in children by the use of temozolomide (TMZ)].
    Voprosy onkologii, 2002, Volume: 48, Issue:3

    Topics: Adolescent; Adult; Age Factors; Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neoplasms; Bra

2002
[Treatment of anaplastic astrocytomas and glioblastomas in children by the use of temozolomide (TMZ)].
    Voprosy onkologii, 2002, Volume: 48, Issue:3

    Topics: Adolescent; Adult; Age Factors; Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neoplasms; Bra

2002
[Complete response of cerebral metastasic melanoma after a combined treatment of radiotherapy and temozolomide].
    Medicina clinica, 2002, Nov-30, Volume: 119, Issue:19

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Humans;

2002
[Complete response of cerebral metastasic melanoma after a combined treatment of radiotherapy and temozolomide].
    Medicina clinica, 2002, Nov-30, Volume: 119, Issue:19

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Humans;

2002
[Complete response of cerebral metastasic melanoma after a combined treatment of radiotherapy and temozolomide].
    Medicina clinica, 2002, Nov-30, Volume: 119, Issue:19

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Humans;

2002
Use of temozolomide with other cytotoxic chemotherapy in the treatment of patients with recurrent brain metastases from lung cancer.
    The oncologist, 2003, Volume: 8, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms;

2003
Use of temozolomide with other cytotoxic chemotherapy in the treatment of patients with recurrent brain metastases from lung cancer.
    The oncologist, 2003, Volume: 8, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms;

2003
Use of temozolomide with other cytotoxic chemotherapy in the treatment of patients with recurrent brain metastases from lung cancer.
    The oncologist, 2003, Volume: 8, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms;

2003
Interobserver variability in the radiological assessment of response to chemotherapy in glioma.
    Neurology, 2003, Mar-11, Volume: 60, Issue:5

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Astrocytoma; Brain Neoplasms; Carboplat

2003
Interobserver variability in the radiological assessment of response to chemotherapy in glioma.
    Neurology, 2003, Mar-11, Volume: 60, Issue:5

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Astrocytoma; Brain Neoplasms; Carboplat

2003
Interobserver variability in the radiological assessment of response to chemotherapy in glioma.
    Neurology, 2003, Mar-11, Volume: 60, Issue:5

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Astrocytoma; Brain Neoplasms; Carboplat

2003
Impact of chromosome 1p status in response of oligodendroglioma to temozolomide: preliminary results.
    Journal of neuro-oncology, 2003, Volume: 61, Issue:3

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chromosomes, Human, Pair 1; Dacarba

2003
Impact of chromosome 1p status in response of oligodendroglioma to temozolomide: preliminary results.
    Journal of neuro-oncology, 2003, Volume: 61, Issue:3

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chromosomes, Human, Pair 1; Dacarba

2003
Impact of chromosome 1p status in response of oligodendroglioma to temozolomide: preliminary results.
    Journal of neuro-oncology, 2003, Volume: 61, Issue:3

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chromosomes, Human, Pair 1; Dacarba

2003
Combined effects of temozolomide and the ribonucleotide reductase inhibitors didox and trimidox in malignant brain tumor cells.
    Cancer chemotherapy and pharmacology, 2003, Volume: 52, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Benzamidines; Brain Neoplasms; Dacarbazine; Drug Synergism; Enzym

2003
Combined effects of temozolomide and the ribonucleotide reductase inhibitors didox and trimidox in malignant brain tumor cells.
    Cancer chemotherapy and pharmacology, 2003, Volume: 52, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Benzamidines; Brain Neoplasms; Dacarbazine; Drug Synergism; Enzym

2003
Combined effects of temozolomide and the ribonucleotide reductase inhibitors didox and trimidox in malignant brain tumor cells.
    Cancer chemotherapy and pharmacology, 2003, Volume: 52, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Benzamidines; Brain Neoplasms; Dacarbazine; Drug Synergism; Enzym

2003
Temozolomide as an alternative to irradiation for elderly patients with newly diagnosed malignant gliomas.
    Cancer, 2003, May-01, Volume: 97, Issue:9

    Topics: Administration, Oral; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; C

2003
Temozolomide as an alternative to irradiation for elderly patients with newly diagnosed malignant gliomas.
    Cancer, 2003, May-01, Volume: 97, Issue:9

    Topics: Administration, Oral; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; C

2003
Temozolomide as an alternative to irradiation for elderly patients with newly diagnosed malignant gliomas.
    Cancer, 2003, May-01, Volume: 97, Issue:9

    Topics: Administration, Oral; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; C

2003
Metabolic activation of temozolomide measured in vivo using positron emission tomography.
    Cancer research, 2003, May-15, Volume: 63, Issue:10

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Biotransformation; Brain Neoplasms; Carbon Dioxide;

2003
Metabolic activation of temozolomide measured in vivo using positron emission tomography.
    Cancer research, 2003, May-15, Volume: 63, Issue:10

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Biotransformation; Brain Neoplasms; Carbon Dioxide;

2003
Metabolic activation of temozolomide measured in vivo using positron emission tomography.
    Cancer research, 2003, May-15, Volume: 63, Issue:10

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Biotransformation; Brain Neoplasms; Carbon Dioxide;

2003
Formation of DNA adducts and induction of lacI mutations in Big Blue Rat-2 cells treated with temozolomide: implications for the treatment of low-grade adult and pediatric brain tumors.
    Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2003, Volume: 12, Issue:6

    Topics: Alkylation; Animals; Antineoplastic Agents, Alkylating; Biomarkers, Tumor; Brain Neoplasms; Dacarbaz

2003
Formation of DNA adducts and induction of lacI mutations in Big Blue Rat-2 cells treated with temozolomide: implications for the treatment of low-grade adult and pediatric brain tumors.
    Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2003, Volume: 12, Issue:6

    Topics: Alkylation; Animals; Antineoplastic Agents, Alkylating; Biomarkers, Tumor; Brain Neoplasms; Dacarbaz

2003
Formation of DNA adducts and induction of lacI mutations in Big Blue Rat-2 cells treated with temozolomide: implications for the treatment of low-grade adult and pediatric brain tumors.
    Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2003, Volume: 12, Issue:6

    Topics: Alkylation; Animals; Antineoplastic Agents, Alkylating; Biomarkers, Tumor; Brain Neoplasms; Dacarbaz

2003
Temozolomide: too early for definitive conclusions.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2003, Oct-01, Volume: 21, Issue:19

    Topics: Adult; Age Factors; Antineoplastic Agents, Alkylating; Brain Neoplasms; Child; Clinical Trials as To

2003
Temozolomide: too early for definitive conclusions.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2003, Oct-01, Volume: 21, Issue:19

    Topics: Adult; Age Factors; Antineoplastic Agents, Alkylating; Brain Neoplasms; Child; Clinical Trials as To

2003
Temozolomide: too early for definitive conclusions.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2003, Oct-01, Volume: 21, Issue:19

    Topics: Adult; Age Factors; Antineoplastic Agents, Alkylating; Brain Neoplasms; Child; Clinical Trials as To

2003
Response of recurrent anaplastic ependymoma to a combination of tamoxifen and isotretinoin.
    Neurology, 2003, Oct-14, Volume: 61, Issue:7

    Topics: Adrenal Cortex Hormones; Adult; Antineoplastic Combined Chemotherapy Protocols; Brain; Brain Neoplas

2003
Response of recurrent anaplastic ependymoma to a combination of tamoxifen and isotretinoin.
    Neurology, 2003, Oct-14, Volume: 61, Issue:7

    Topics: Adrenal Cortex Hormones; Adult; Antineoplastic Combined Chemotherapy Protocols; Brain; Brain Neoplas

2003
Response of recurrent anaplastic ependymoma to a combination of tamoxifen and isotretinoin.
    Neurology, 2003, Oct-14, Volume: 61, Issue:7

    Topics: Adrenal Cortex Hormones; Adult; Antineoplastic Combined Chemotherapy Protocols; Brain; Brain Neoplas

2003
Treatment of glioblastoma multiforme in the elderly in functionally non-critical areas. Clinical remarks on 22 patients.
    Journal of experimental & clinical cancer research : CR, 2003, Volume: 22, Issue:3

    Topics: Aged; Aged, 80 and over; Brain Neoplasms; Dacarbazine; Female; Glioblastoma; Humans; Male; Neoplasm

2003
Treatment of glioblastoma multiforme in the elderly in functionally non-critical areas. Clinical remarks on 22 patients.
    Journal of experimental & clinical cancer research : CR, 2003, Volume: 22, Issue:3

    Topics: Aged; Aged, 80 and over; Brain Neoplasms; Dacarbazine; Female; Glioblastoma; Humans; Male; Neoplasm

2003
Treatment of glioblastoma multiforme in the elderly in functionally non-critical areas. Clinical remarks on 22 patients.
    Journal of experimental & clinical cancer research : CR, 2003, Volume: 22, Issue:3

    Topics: Aged; Aged, 80 and over; Brain Neoplasms; Dacarbazine; Female; Glioblastoma; Humans; Male; Neoplasm

2003
Response to low dose temozolomide in radiation induced gliomatosis cerebri.
    Medical and pediatric oncology, 2003, Volume: 41, Issue:6

    Topics: Adolescent; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Female; Humans; Leukemi

2003
Response to low dose temozolomide in radiation induced gliomatosis cerebri.
    Medical and pediatric oncology, 2003, Volume: 41, Issue:6

    Topics: Adolescent; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Female; Humans; Leukemi

2003
Response to low dose temozolomide in radiation induced gliomatosis cerebri.
    Medical and pediatric oncology, 2003, Volume: 41, Issue:6

    Topics: Adolescent; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Female; Humans; Leukemi

2003
Systemic administration of GPI 15427, a novel poly(ADP-ribose) polymerase-1 inhibitor, increases the antitumor activity of temozolomide against intracranial melanoma, glioma, lymphoma.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2003, Nov-01, Volume: 9, Issue:14

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Drug Synergism; Enzyme Inh

2003
Systemic administration of GPI 15427, a novel poly(ADP-ribose) polymerase-1 inhibitor, increases the antitumor activity of temozolomide against intracranial melanoma, glioma, lymphoma.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2003, Nov-01, Volume: 9, Issue:14

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Drug Synergism; Enzyme Inh

2003
Systemic administration of GPI 15427, a novel poly(ADP-ribose) polymerase-1 inhibitor, increases the antitumor activity of temozolomide against intracranial melanoma, glioma, lymphoma.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2003, Nov-01, Volume: 9, Issue:14

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Drug Synergism; Enzyme Inh

2003
Promises and controversies in the management of low-grade glioma.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2003, Volume: 14, Issue:12

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Clinical Trials, Phase II as Topic; Combined Mod

2003
Promises and controversies in the management of low-grade glioma.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2003, Volume: 14, Issue:12

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Clinical Trials, Phase II as Topic; Combined Mod

2003
Promises and controversies in the management of low-grade glioma.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2003, Volume: 14, Issue:12

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Clinical Trials, Phase II as Topic; Combined Mod

2003
Gliomatosis cerebri: clinical, neurochemical and neuroradiological response to temozolomide administration.
    Magnetic resonance imaging, 2003, Volume: 21, Issue:9

    Topics: Antineoplastic Agents, Alkylating; Brain; Brain Neoplasms; Dacarbazine; Humans; Magnetic Resonance I

2003
Gliomatosis cerebri: clinical, neurochemical and neuroradiological response to temozolomide administration.
    Magnetic resonance imaging, 2003, Volume: 21, Issue:9

    Topics: Antineoplastic Agents, Alkylating; Brain; Brain Neoplasms; Dacarbazine; Humans; Magnetic Resonance I

2003
Gliomatosis cerebri: clinical, neurochemical and neuroradiological response to temozolomide administration.
    Magnetic resonance imaging, 2003, Volume: 21, Issue:9

    Topics: Antineoplastic Agents, Alkylating; Brain; Brain Neoplasms; Dacarbazine; Humans; Magnetic Resonance I

2003
[Temozolomide in patients with melanoma brain metastases treated with whole brain irradiation].
    Medicina clinica, 2004, Mar-27, Volume: 122, Issue:11

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modalit

2004
[Temozolomide in patients with melanoma brain metastases treated with whole brain irradiation].
    Medicina clinica, 2004, Mar-27, Volume: 122, Issue:11

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modalit

2004
[Temozolomide in patients with melanoma brain metastases treated with whole brain irradiation].
    Medicina clinica, 2004, Mar-27, Volume: 122, Issue:11

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modalit

2004
Irinotecan-induced interstitial pneumonia.
    The Lancet. Oncology, 2004, Volume: 5, Issue:5

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Camptothecin; Dacarbazine; D

2004
Irinotecan-induced interstitial pneumonia.
    The Lancet. Oncology, 2004, Volume: 5, Issue:5

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Camptothecin; Dacarbazine; D

2004
Irinotecan-induced interstitial pneumonia.
    The Lancet. Oncology, 2004, Volume: 5, Issue:5

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Camptothecin; Dacarbazine; D

2004
Complete response of multiple melanoma brain metastases after treatment with temozolomide.
    Onkologie, 2004, Volume: 27, Issue:2

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Female; Humans; Magnetic Resonance

2004
Complete response of multiple melanoma brain metastases after treatment with temozolomide.
    Onkologie, 2004, Volume: 27, Issue:2

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Female; Humans; Magnetic Resonance

2004
Complete response of multiple melanoma brain metastases after treatment with temozolomide.
    Onkologie, 2004, Volume: 27, Issue:2

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Female; Humans; Magnetic Resonance

2004
Long-term outcome of oligodendrogliomas.
    Neurology, 2004, May-25, Volume: 62, Issue:10

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Biopsy; Brain Neoplasms; Ci

2004
Long-term outcome of oligodendrogliomas.
    Neurology, 2004, May-25, Volume: 62, Issue:10

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Biopsy; Brain Neoplasms; Ci

2004
Long-term outcome of oligodendrogliomas.
    Neurology, 2004, May-25, Volume: 62, Issue:10

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Biopsy; Brain Neoplasms; Ci

2004
Plasma and cerebrospinal fluid population pharmacokinetics of temozolomide in malignant glioma patients.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2004, Jun-01, Volume: 10, Issue:11

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Area Under Curve; Brain Neoplasms; Chromatography, H

2004
Plasma and cerebrospinal fluid population pharmacokinetics of temozolomide in malignant glioma patients.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2004, Jun-01, Volume: 10, Issue:11

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Area Under Curve; Brain Neoplasms; Chromatography, H

2004
Plasma and cerebrospinal fluid population pharmacokinetics of temozolomide in malignant glioma patients.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2004, Jun-01, Volume: 10, Issue:11

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Area Under Curve; Brain Neoplasms; Chromatography, H

2004
Cooperative function of Chk1 and p38 pathways in activating G2 arrest following exposure to temozolomide.
    Journal of neurosurgery, 2004, Volume: 100, Issue:6

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Checkpoint Kinase 1; Dacarbazine; Drug Resistanc

2004
Cooperative function of Chk1 and p38 pathways in activating G2 arrest following exposure to temozolomide.
    Journal of neurosurgery, 2004, Volume: 100, Issue:6

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Checkpoint Kinase 1; Dacarbazine; Drug Resistanc

2004
Cooperative function of Chk1 and p38 pathways in activating G2 arrest following exposure to temozolomide.
    Journal of neurosurgery, 2004, Volume: 100, Issue:6

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Checkpoint Kinase 1; Dacarbazine; Drug Resistanc

2004
Quality assurance of the EORTC 26981/22981; NCIC CE3 intergroup trial on radiotherapy with or without temozolomide for newly-diagnosed glioblastoma multiforme: the individual case review.
    European journal of cancer (Oxford, England : 1990), 2004, Volume: 40, Issue:11

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Clinical Protocols; Clinical Trials, Phase III a

2004
Quality assurance of the EORTC 26981/22981; NCIC CE3 intergroup trial on radiotherapy with or without temozolomide for newly-diagnosed glioblastoma multiforme: the individual case review.
    European journal of cancer (Oxford, England : 1990), 2004, Volume: 40, Issue:11

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Clinical Protocols; Clinical Trials, Phase III a

2004
Quality assurance of the EORTC 26981/22981; NCIC CE3 intergroup trial on radiotherapy with or without temozolomide for newly-diagnosed glioblastoma multiforme: the individual case review.
    European journal of cancer (Oxford, England : 1990), 2004, Volume: 40, Issue:11

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Clinical Protocols; Clinical Trials, Phase III a

2004
Gliomatosis cerebri: better definition, better treatment.
    Neurology, 2004, Jul-27, Volume: 63, Issue:2

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Astrocyt

2004
Gliomatosis cerebri: better definition, better treatment.
    Neurology, 2004, Jul-27, Volume: 63, Issue:2

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Astrocyt

2004
Gliomatosis cerebri: better definition, better treatment.
    Neurology, 2004, Jul-27, Volume: 63, Issue:2

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Astrocyt

2004
Temozolomide as initial treatment for adults with low-grade oligodendrogliomas or oligoastrocytomas and correlation with chromosome 1p deletions.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2004, Aug-01, Volume: 22, Issue:15

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neoplasms; Chromosome Deletion; C

2004
Temozolomide as initial treatment for adults with low-grade oligodendrogliomas or oligoastrocytomas and correlation with chromosome 1p deletions.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2004, Aug-01, Volume: 22, Issue:15

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neoplasms; Chromosome Deletion; C

2004
Temozolomide as initial treatment for adults with low-grade oligodendrogliomas or oligoastrocytomas and correlation with chromosome 1p deletions.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2004, Aug-01, Volume: 22, Issue:15

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neoplasms; Chromosome Deletion; C

2004
CpG island hypermethylation of the DNA repair enzyme methyltransferase predicts response to temozolomide in primary gliomas.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2004, Aug-01, Volume: 10, Issue:15

    Topics: Adult; Aged; Alkylating Agents; Brain Neoplasms; Carmustine; CpG Islands; Dacarbazine; DNA; DNA Meth

2004
CpG island hypermethylation of the DNA repair enzyme methyltransferase predicts response to temozolomide in primary gliomas.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2004, Aug-01, Volume: 10, Issue:15

    Topics: Adult; Aged; Alkylating Agents; Brain Neoplasms; Carmustine; CpG Islands; Dacarbazine; DNA; DNA Meth

2004
CpG island hypermethylation of the DNA repair enzyme methyltransferase predicts response to temozolomide in primary gliomas.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2004, Aug-01, Volume: 10, Issue:15

    Topics: Adult; Aged; Alkylating Agents; Brain Neoplasms; Carmustine; CpG Islands; Dacarbazine; DNA; DNA Meth

2004
Effect of association of temozolomide with other chemotherapic agents on cell growth inhibition in glioma cell lines.
    Oncology research, 2004, Volume: 14, Issue:7-8

    Topics: Antineoplastic Agents; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Phytogenic; Antineo

2004
Effect of association of temozolomide with other chemotherapic agents on cell growth inhibition in glioma cell lines.
    Oncology research, 2004, Volume: 14, Issue:7-8

    Topics: Antineoplastic Agents; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Phytogenic; Antineo

2004
Effect of association of temozolomide with other chemotherapic agents on cell growth inhibition in glioma cell lines.
    Oncology research, 2004, Volume: 14, Issue:7-8

    Topics: Antineoplastic Agents; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Phytogenic; Antineo

2004
Transcriptional targeting of adenovirally delivered tumor necrosis factor alpha by temozolomide in experimental glioblastoma.
    Cancer research, 2004, Sep-15, Volume: 64, Issue:18

    Topics: Adenoviruses, Human; Animals; Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cell Li

2004
Transcriptional targeting of adenovirally delivered tumor necrosis factor alpha by temozolomide in experimental glioblastoma.
    Cancer research, 2004, Sep-15, Volume: 64, Issue:18

    Topics: Adenoviruses, Human; Animals; Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cell Li

2004
Transcriptional targeting of adenovirally delivered tumor necrosis factor alpha by temozolomide in experimental glioblastoma.
    Cancer research, 2004, Sep-15, Volume: 64, Issue:18

    Topics: Adenoviruses, Human; Animals; Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cell Li

2004
Can we afford to add chemotherapy to radiotherapy for glioblastoma multiforme? Cost-identification analysis of concomitant and adjuvant treatment with temozolomide until patient death.
    Cancer, 2004, Nov-01, Volume: 101, Issue:9

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Cost-Ben

2004
Can we afford to add chemotherapy to radiotherapy for glioblastoma multiforme? Cost-identification analysis of concomitant and adjuvant treatment with temozolomide until patient death.
    Cancer, 2004, Nov-01, Volume: 101, Issue:9

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Cost-Ben

2004
Can we afford to add chemotherapy to radiotherapy for glioblastoma multiforme? Cost-identification analysis of concomitant and adjuvant treatment with temozolomide until patient death.
    Cancer, 2004, Nov-01, Volume: 101, Issue:9

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Cost-Ben

2004
Convection-enhanced delivery of tumor necrosis factor-related apoptosis-inducing ligand with systemic administration of temozolomide prolongs survival in an intracranial glioblastoma xenograft model.
    Cancer research, 2004, Oct-01, Volume: 64, Issue:19

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Apoptosis Regulatory Proteins; B

2004
Convection-enhanced delivery of tumor necrosis factor-related apoptosis-inducing ligand with systemic administration of temozolomide prolongs survival in an intracranial glioblastoma xenograft model.
    Cancer research, 2004, Oct-01, Volume: 64, Issue:19

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Apoptosis Regulatory Proteins; B

2004
Convection-enhanced delivery of tumor necrosis factor-related apoptosis-inducing ligand with systemic administration of temozolomide prolongs survival in an intracranial glioblastoma xenograft model.
    Cancer research, 2004, Oct-01, Volume: 64, Issue:19

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Apoptosis Regulatory Proteins; B

2004
Temozolomide for the treatment of recurrent supratentorial glioma: results of a compassionate use program in Belgium.
    Journal of neuro-oncology, 2004, Volume: 70, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Belgium; Brain Neoplasms; Dacarba

2004
Temozolomide for the treatment of recurrent supratentorial glioma: results of a compassionate use program in Belgium.
    Journal of neuro-oncology, 2004, Volume: 70, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Belgium; Brain Neoplasms; Dacarba

2004
Temozolomide for the treatment of recurrent supratentorial glioma: results of a compassionate use program in Belgium.
    Journal of neuro-oncology, 2004, Volume: 70, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Belgium; Brain Neoplasms; Dacarba

2004
Intracranial metastatic esthesioneuroblastoma responsive to temozolomide.
    Journal of neuro-oncology, 2004, Volume: 70, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Esthesioneuroblastoma, Olfactory; F

2004
Intracranial metastatic esthesioneuroblastoma responsive to temozolomide.
    Journal of neuro-oncology, 2004, Volume: 70, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Esthesioneuroblastoma, Olfactory; F

2004
Intracranial metastatic esthesioneuroblastoma responsive to temozolomide.
    Journal of neuro-oncology, 2004, Volume: 70, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Esthesioneuroblastoma, Olfactory; F

2004
The piperidine nitroxide Tempol potentiates the cytotoxic effects of temozolomide in human glioblastoma cells.
    International journal of oncology, 2004, Volume: 25, Issue:6

    Topics: Antineoplastic Agents, Alkylating; Antioxidants; Apoptosis; Brain Neoplasms; Cell Cycle; Cyclic N-Ox

2004
The piperidine nitroxide Tempol potentiates the cytotoxic effects of temozolomide in human glioblastoma cells.
    International journal of oncology, 2004, Volume: 25, Issue:6

    Topics: Antineoplastic Agents, Alkylating; Antioxidants; Apoptosis; Brain Neoplasms; Cell Cycle; Cyclic N-Ox

2004
The piperidine nitroxide Tempol potentiates the cytotoxic effects of temozolomide in human glioblastoma cells.
    International journal of oncology, 2004, Volume: 25, Issue:6

    Topics: Antineoplastic Agents, Alkylating; Antioxidants; Apoptosis; Brain Neoplasms; Cell Cycle; Cyclic N-Ox

2004
Continuous low-dose chemotherapy plus inhibition of cyclooxygenase-2 as an antiangiogenic therapy of glioblastoma multiforme.
    Journal of cancer research and clinical oncology, 2005, Volume: 131, Issue:1

    Topics: Adult; Angiogenesis Inhibitors; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemother

2005
Continuous low-dose chemotherapy plus inhibition of cyclooxygenase-2 as an antiangiogenic therapy of glioblastoma multiforme.
    Journal of cancer research and clinical oncology, 2005, Volume: 131, Issue:1

    Topics: Adult; Angiogenesis Inhibitors; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemother

2005
Continuous low-dose chemotherapy plus inhibition of cyclooxygenase-2 as an antiangiogenic therapy of glioblastoma multiforme.
    Journal of cancer research and clinical oncology, 2005, Volume: 131, Issue:1

    Topics: Adult; Angiogenesis Inhibitors; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemother

2005
Pharmacokinetic model-predicted anticancer drug concentrations in human tumors.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2004, Dec-01, Volume: 10, Issue:23

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carboplatin; Computer Simu

2004
Pharmacokinetic model-predicted anticancer drug concentrations in human tumors.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2004, Dec-01, Volume: 10, Issue:23

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carboplatin; Computer Simu

2004
Pharmacokinetic model-predicted anticancer drug concentrations in human tumors.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2004, Dec-01, Volume: 10, Issue:23

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carboplatin; Computer Simu

2004
Hierarchical models for tumor xenograft experiments in drug development.
    Journal of biopharmaceutical statistics, 2004, Volume: 14, Issue:4

    Topics: Algorithms; Animals; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Antineoplastic Combin

2004
Hierarchical models for tumor xenograft experiments in drug development.
    Journal of biopharmaceutical statistics, 2004, Volume: 14, Issue:4

    Topics: Algorithms; Animals; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Antineoplastic Combin

2004
Hierarchical models for tumor xenograft experiments in drug development.
    Journal of biopharmaceutical statistics, 2004, Volume: 14, Issue:4

    Topics: Algorithms; Animals; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Antineoplastic Combin

2004
Making inferences about projected completors in longitudinal studies.
    Journal of biopharmaceutical statistics, 2004, Volume: 14, Issue:4

    Topics: Algorithms; Animals; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Antineoplastic Combin

2004
Making inferences about projected completors in longitudinal studies.
    Journal of biopharmaceutical statistics, 2004, Volume: 14, Issue:4

    Topics: Algorithms; Animals; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Antineoplastic Combin

2004
Making inferences about projected completors in longitudinal studies.
    Journal of biopharmaceutical statistics, 2004, Volume: 14, Issue:4

    Topics: Algorithms; Animals; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Antineoplastic Combin

2004
Dexamethasone protected human glioblastoma U87MG cells from temozolomide induced apoptosis by maintaining Bax:Bcl-2 ratio and preventing proteolytic activities.
    Molecular cancer, 2004, Dec-08, Volume: 3, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Antineoplastic Agents, Hormonal; Apoptosis; bcl-2-Associated X Pr

2004
Dexamethasone protected human glioblastoma U87MG cells from temozolomide induced apoptosis by maintaining Bax:Bcl-2 ratio and preventing proteolytic activities.
    Molecular cancer, 2004, Dec-08, Volume: 3, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Antineoplastic Agents, Hormonal; Apoptosis; bcl-2-Associated X Pr

2004
Dexamethasone protected human glioblastoma U87MG cells from temozolomide induced apoptosis by maintaining Bax:Bcl-2 ratio and preventing proteolytic activities.
    Molecular cancer, 2004, Dec-08, Volume: 3, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Antineoplastic Agents, Hormonal; Apoptosis; bcl-2-Associated X Pr

2004
Innovative therapy for patients with brain metastases: oral treatments.
    Journal of chemotherapy (Florence, Italy), 2004, Volume: 16 Suppl 5

    Topics: Administration, Oral; Brain Neoplasms; Capecitabine; Combined Modality Therapy; Dacarbazine; Deoxycy

2004
Innovative therapy for patients with brain metastases: oral treatments.
    Journal of chemotherapy (Florence, Italy), 2004, Volume: 16 Suppl 5

    Topics: Administration, Oral; Brain Neoplasms; Capecitabine; Combined Modality Therapy; Dacarbazine; Deoxycy

2004
Innovative therapy for patients with brain metastases: oral treatments.
    Journal of chemotherapy (Florence, Italy), 2004, Volume: 16 Suppl 5

    Topics: Administration, Oral; Brain Neoplasms; Capecitabine; Combined Modality Therapy; Dacarbazine; Deoxycy

2004
Low-grade primary meningeal lymphoma: case report and review of the literature.
    Neurosurgical review, 2005, Volume: 28, Issue:3

    Topics: Aged; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Gliobl

2005
Low-grade primary meningeal lymphoma: case report and review of the literature.
    Neurosurgical review, 2005, Volume: 28, Issue:3

    Topics: Aged; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Gliobl

2005
Low-grade primary meningeal lymphoma: case report and review of the literature.
    Neurosurgical review, 2005, Volume: 28, Issue:3

    Topics: Aged; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Gliobl

2005
Neoadjuvant temozolomide followed by complete resection of a 1p- and 19q-deleted anaplastic oligoastrocytoma: case study.
    Neuro-oncology, 2005, Volume: 7, Issue:1

    Topics: Adult; Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neoplasms; Chromosome Deletion; Chromos

2005
Neoadjuvant temozolomide followed by complete resection of a 1p- and 19q-deleted anaplastic oligoastrocytoma: case study.
    Neuro-oncology, 2005, Volume: 7, Issue:1

    Topics: Adult; Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neoplasms; Chromosome Deletion; Chromos

2005
Neoadjuvant temozolomide followed by complete resection of a 1p- and 19q-deleted anaplastic oligoastrocytoma: case study.
    Neuro-oncology, 2005, Volume: 7, Issue:1

    Topics: Adult; Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neoplasms; Chromosome Deletion; Chromos

2005
Successful treatment of a chemoresistant tumor with temozolomide in an adult patient: report of a recurrent intracranial mesenchymal chondrosarcoma.
    Journal of neuro-oncology, 2005, Volume: 71, Issue:3

    Topics: Adult; Antineoplastic Agents, Alkylating; Bone Neoplasms; Brain Neoplasms; Chondrosarcoma, Mesenchym

2005
Successful treatment of a chemoresistant tumor with temozolomide in an adult patient: report of a recurrent intracranial mesenchymal chondrosarcoma.
    Journal of neuro-oncology, 2005, Volume: 71, Issue:3

    Topics: Adult; Antineoplastic Agents, Alkylating; Bone Neoplasms; Brain Neoplasms; Chondrosarcoma, Mesenchym

2005
Successful treatment of a chemoresistant tumor with temozolomide in an adult patient: report of a recurrent intracranial mesenchymal chondrosarcoma.
    Journal of neuro-oncology, 2005, Volume: 71, Issue:3

    Topics: Adult; Antineoplastic Agents, Alkylating; Bone Neoplasms; Brain Neoplasms; Chondrosarcoma, Mesenchym

2005
Salvage therapy for primary CNS lymphoma with a combination of rituximab and temozolomide.
    Neurology, 2005, Mar-08, Volume: 64, Issue:5

    Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Agents; Antineoplasti

2005
Salvage therapy for primary CNS lymphoma with a combination of rituximab and temozolomide.
    Neurology, 2005, Mar-08, Volume: 64, Issue:5

    Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Agents; Antineoplasti

2005
Salvage therapy for primary CNS lymphoma with a combination of rituximab and temozolomide.
    Neurology, 2005, Mar-08, Volume: 64, Issue:5

    Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Agents; Antineoplasti

2005
Efficacy and toxicity of postoperative temozolomide radiochemotherapy in malignant glioma.
    Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 2005, Volume: 181, Issue:3

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Brain Neoplasms; Combined Modality Therapy; Dacarbaz

2005
Efficacy and toxicity of postoperative temozolomide radiochemotherapy in malignant glioma.
    Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 2005, Volume: 181, Issue:3

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Brain Neoplasms; Combined Modality Therapy; Dacarbaz

2005
Efficacy and toxicity of postoperative temozolomide radiochemotherapy in malignant glioma.
    Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 2005, Volume: 181, Issue:3

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Brain Neoplasms; Combined Modality Therapy; Dacarbaz

2005
MGMT gene silencing and benefit from temozolomide in glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant; Dacarbazine; Disease-Fre

2005
MGMT gene silencing and benefit from temozolomide in glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant; Dacarbazine; Disease-Fre

2005
MGMT gene silencing and benefit from temozolomide in glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant; Dacarbazine; Disease-Fre

2005
MGMT gene silencing and benefit from temozolomide in glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant; Dacarbazine; Disease-Fre

2005
MGMT gene silencing and benefit from temozolomide in glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant; Dacarbazine; Disease-Fre

2005
MGMT gene silencing and benefit from temozolomide in glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant; Dacarbazine; Disease-Fre

2005
MGMT gene silencing and benefit from temozolomide in glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant; Dacarbazine; Disease-Fre

2005
MGMT gene silencing and benefit from temozolomide in glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant; Dacarbazine; Disease-Fre

2005
MGMT gene silencing and benefit from temozolomide in glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant; Dacarbazine; Disease-Fre

2005
MGMT gene silencing and benefit from temozolomide in glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant; Dacarbazine; Disease-Fre

2005
MGMT gene silencing and benefit from temozolomide in glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant; Dacarbazine; Disease-Fre

2005
MGMT gene silencing and benefit from temozolomide in glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant; Dacarbazine; Disease-Fre

2005
MGMT gene silencing and benefit from temozolomide in glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant; Dacarbazine; Disease-Fre

2005
MGMT gene silencing and benefit from temozolomide in glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant; Dacarbazine; Disease-Fre

2005
MGMT gene silencing and benefit from temozolomide in glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant; Dacarbazine; Disease-Fre

2005
MGMT gene silencing and benefit from temozolomide in glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant; Dacarbazine; Disease-Fre

2005
MGMT gene silencing and benefit from temozolomide in glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant; Dacarbazine; Disease-Fre

2005
MGMT gene silencing and benefit from temozolomide in glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant; Dacarbazine; Disease-Fre

2005
MGMT gene silencing and benefit from temozolomide in glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant; Dacarbazine; Disease-Fre

2005
MGMT gene silencing and benefit from temozolomide in glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant; Dacarbazine; Disease-Fre

2005
MGMT gene silencing and benefit from temozolomide in glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant; Dacarbazine; Disease-Fre

2005
MGMT gene silencing and benefit from temozolomide in glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant; Dacarbazine; Disease-Fre

2005
MGMT gene silencing and benefit from temozolomide in glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant; Dacarbazine; Disease-Fre

2005
MGMT gene silencing and benefit from temozolomide in glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant; Dacarbazine; Disease-Fre

2005
MGMT gene silencing and benefit from temozolomide in glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant; Dacarbazine; Disease-Fre

2005
MGMT gene silencing and benefit from temozolomide in glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant; Dacarbazine; Disease-Fre

2005
MGMT gene silencing and benefit from temozolomide in glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant; Dacarbazine; Disease-Fre

2005
MGMT gene silencing and benefit from temozolomide in glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant; Dacarbazine; Disease-Fre

2005
MGMT gene silencing and benefit from temozolomide in glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant; Dacarbazine; Disease-Fre

2005
MGMT gene silencing and benefit from temozolomide in glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant; Dacarbazine; Disease-Fre

2005
MGMT gene silencing and benefit from temozolomide in glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant; Dacarbazine; Disease-Fre

2005
MGMT gene silencing and benefit from temozolomide in glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant; Dacarbazine; Disease-Fre

2005
MGMT gene silencing and benefit from temozolomide in glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant; Dacarbazine; Disease-Fre

2005
MGMT gene silencing and benefit from temozolomide in glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant; Dacarbazine; Disease-Fre

2005
MGMT gene silencing and benefit from temozolomide in glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant; Dacarbazine; Disease-Fre

2005
MGMT gene silencing and benefit from temozolomide in glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant; Dacarbazine; Disease-Fre

2005
MGMT gene silencing and benefit from temozolomide in glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant; Dacarbazine; Disease-Fre

2005
MGMT gene silencing and benefit from temozolomide in glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant; Dacarbazine; Disease-Fre

2005
MGMT gene silencing and benefit from temozolomide in glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant; Dacarbazine; Disease-Fre

2005
MGMT gene silencing and benefit from temozolomide in glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant; Dacarbazine; Disease-Fre

2005
MGMT gene silencing and benefit from temozolomide in glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant; Dacarbazine; Disease-Fre

2005
MGMT gene silencing and benefit from temozolomide in glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant; Dacarbazine; Disease-Fre

2005
MGMT gene silencing and benefit from temozolomide in glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant; Dacarbazine; Disease-Fre

2005
MGMT gene silencing and benefit from temozolomide in glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant; Dacarbazine; Disease-Fre

2005
MGMT gene silencing and benefit from temozolomide in glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant; Dacarbazine; Disease-Fre

2005
MGMT gene silencing and benefit from temozolomide in glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant; Dacarbazine; Disease-Fre

2005
MGMT gene silencing and benefit from temozolomide in glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant; Dacarbazine; Disease-Fre

2005
MGMT gene silencing and benefit from temozolomide in glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant; Dacarbazine; Disease-Fre

2005
MGMT gene silencing and benefit from temozolomide in glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant; Dacarbazine; Disease-Fre

2005
MGMT gene silencing and benefit from temozolomide in glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant; Dacarbazine; Disease-Fre

2005
MGMT gene silencing and benefit from temozolomide in glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant; Dacarbazine; Disease-Fre

2005
MGMT gene silencing and benefit from temozolomide in glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant; Dacarbazine; Disease-Fre

2005
MGMT gene silencing and benefit from temozolomide in glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant; Dacarbazine; Disease-Fre

2005
MGMT gene silencing and benefit from temozolomide in glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant; Dacarbazine; Disease-Fre

2005
MGMT gene silencing and benefit from temozolomide in glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant; Dacarbazine; Disease-Fre

2005
MGMT gene silencing and benefit from temozolomide in glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant; Dacarbazine; Disease-Fre

2005
MGMT gene silencing and benefit from temozolomide in glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant; Dacarbazine; Disease-Fre

2005
MGMT gene silencing and benefit from temozolomide in glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant; Dacarbazine; Disease-Fre

2005
MGMT gene silencing and benefit from temozolomide in glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant; Dacarbazine; Disease-Fre

2005
MGMT gene silencing and benefit from temozolomide in glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant; Dacarbazine; Disease-Fre

2005
MGMT gene silencing and benefit from temozolomide in glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant; Dacarbazine; Disease-Fre

2005
MGMT gene silencing and benefit from temozolomide in glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant; Dacarbazine; Disease-Fre

2005
MGMT gene silencing and benefit from temozolomide in glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant; Dacarbazine; Disease-Fre

2005
MGMT gene silencing and benefit from temozolomide in glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant; Dacarbazine; Disease-Fre

2005
MGMT gene silencing and benefit from temozolomide in glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant; Dacarbazine; Disease-Fre

2005
MGMT gene silencing and benefit from temozolomide in glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant; Dacarbazine; Disease-Fre

2005
MGMT gene silencing and benefit from temozolomide in glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant; Dacarbazine; Disease-Fre

2005
MGMT gene silencing and benefit from temozolomide in glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant; Dacarbazine; Disease-Fre

2005
MGMT gene silencing and benefit from temozolomide in glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant; Dacarbazine; Disease-Fre

2005
MGMT gene silencing and benefit from temozolomide in glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant; Dacarbazine; Disease-Fre

2005
MGMT gene silencing and benefit from temozolomide in glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant; Dacarbazine; Disease-Fre

2005
MGMT gene silencing and benefit from temozolomide in glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant; Dacarbazine; Disease-Fre

2005
MGMT gene silencing and benefit from temozolomide in glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant; Dacarbazine; Disease-Fre

2005
MGMT gene silencing and benefit from temozolomide in glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant; Dacarbazine; Disease-Fre

2005
MGMT gene silencing and benefit from temozolomide in glioblastoma.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant; Dacarbazine; Disease-Fre

2005
Chemotherapy for brain tumors--a new beginning.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adult; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Brain Neop

2005
Chemotherapy for brain tumors--a new beginning.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adult; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Brain Neop

2005
Chemotherapy for brain tumors--a new beginning.
    The New England journal of medicine, 2005, Mar-10, Volume: 352, Issue:10

    Topics: Adult; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Brain Neop

2005
Cerebral metastases of malignant melanoma: contemporary treatment modalities and survival outcome.
    Neoplasma, 2005, Volume: 52, Issue:2

    Topics: Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Di

2005
Cerebral metastases of malignant melanoma: contemporary treatment modalities and survival outcome.
    Neoplasma, 2005, Volume: 52, Issue:2

    Topics: Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Di

2005
Cerebral metastases of malignant melanoma: contemporary treatment modalities and survival outcome.
    Neoplasma, 2005, Volume: 52, Issue:2

    Topics: Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Di

2005
Pharmaceutical-mediated inactivation of p53 sensitizes U87MG glioma cells to BCNU and temozolomide.
    International journal of cancer, 2005, Aug-20, Volume: 116, Issue:2

    Topics: Antineoplastic Agents, Alkylating; Benzothiazoles; Brain Neoplasms; Carmustine; Dacarbazine; DNA Dam

2005
Pharmaceutical-mediated inactivation of p53 sensitizes U87MG glioma cells to BCNU and temozolomide.
    International journal of cancer, 2005, Aug-20, Volume: 116, Issue:2

    Topics: Antineoplastic Agents, Alkylating; Benzothiazoles; Brain Neoplasms; Carmustine; Dacarbazine; DNA Dam

2005
Pharmaceutical-mediated inactivation of p53 sensitizes U87MG glioma cells to BCNU and temozolomide.
    International journal of cancer, 2005, Aug-20, Volume: 116, Issue:2

    Topics: Antineoplastic Agents, Alkylating; Benzothiazoles; Brain Neoplasms; Carmustine; Dacarbazine; DNA Dam

2005
Temozolomide in combination with BCNU before and after radiotherapy in patients with inoperable newly diagnosed glioblastoma multiforme.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2005, Volume: 16, Issue:7

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carmustine; Combined M

2005
Temozolomide in combination with BCNU before and after radiotherapy in patients with inoperable newly diagnosed glioblastoma multiforme.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2005, Volume: 16, Issue:7

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carmustine; Combined M

2005
Temozolomide in combination with BCNU before and after radiotherapy in patients with inoperable newly diagnosed glioblastoma multiforme.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2005, Volume: 16, Issue:7

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carmustine; Combined M

2005
Treatment of brain metastases from melanoma.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2005, May-01, Volume: 23, Issue:13

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Clinical Trials as Topic; Dacarbazine; Endpoint

2005
Treatment of brain metastases from melanoma.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2005, May-01, Volume: 23, Issue:13

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Clinical Trials as Topic; Dacarbazine; Endpoint

2005
Treatment of brain metastases from melanoma.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2005, May-01, Volume: 23, Issue:13

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Clinical Trials as Topic; Dacarbazine; Endpoint

2005
Combined cimetidine and temozolomide, compared with temozolomide alone: significant increases in survival in nude mice bearing U373 human glioblastoma multiforme orthotopic xenografts.
    Journal of neurosurgery, 2005, Volume: 102, Issue:4

    Topics: Adjuvants, Immunologic; Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cimetidine; Dac

2005
Combined cimetidine and temozolomide, compared with temozolomide alone: significant increases in survival in nude mice bearing U373 human glioblastoma multiforme orthotopic xenografts.
    Journal of neurosurgery, 2005, Volume: 102, Issue:4

    Topics: Adjuvants, Immunologic; Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cimetidine; Dac

2005
Combined cimetidine and temozolomide, compared with temozolomide alone: significant increases in survival in nude mice bearing U373 human glioblastoma multiforme orthotopic xenografts.
    Journal of neurosurgery, 2005, Volume: 102, Issue:4

    Topics: Adjuvants, Immunologic; Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cimetidine; Dac

2005
Cytotoxic T cell targeting of TRP-2 sensitizes human malignant glioma to chemotherapy.
    Oncogene, 2005, Aug-04, Volume: 24, Issue:33

    Topics: Antigens, Neoplasm; Antineoplastic Agents; Brain Neoplasms; Carboplatin; Combined Modality Therapy;

2005
Cytotoxic T cell targeting of TRP-2 sensitizes human malignant glioma to chemotherapy.
    Oncogene, 2005, Aug-04, Volume: 24, Issue:33

    Topics: Antigens, Neoplasm; Antineoplastic Agents; Brain Neoplasms; Carboplatin; Combined Modality Therapy;

2005
Cytotoxic T cell targeting of TRP-2 sensitizes human malignant glioma to chemotherapy.
    Oncogene, 2005, Aug-04, Volume: 24, Issue:33

    Topics: Antigens, Neoplasm; Antineoplastic Agents; Brain Neoplasms; Carboplatin; Combined Modality Therapy;

2005
Treatment of brain tumors.
    The New England journal of medicine, 2005, Jun-02, Volume: 352, Issue:22

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant; Dacarbazine; Gene Silenc

2005
Treatment of brain tumors.
    The New England journal of medicine, 2005, Jun-02, Volume: 352, Issue:22

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant; Dacarbazine; Gene Silenc

2005
Treatment of brain tumors.
    The New England journal of medicine, 2005, Jun-02, Volume: 352, Issue:22

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant; Dacarbazine; Gene Silenc

2005
Treatment of brain tumors.
    The New England journal of medicine, 2005, Jun-02, Volume: 352, Issue:22

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Carmustine; Chemotherapy, Adjuvant; Dacarbazine;

2005
Treatment of brain tumors.
    The New England journal of medicine, 2005, Jun-02, Volume: 352, Issue:22

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Carmustine; Chemotherapy, Adjuvant; Dacarbazine;

2005
Treatment of brain tumors.
    The New England journal of medicine, 2005, Jun-02, Volume: 352, Issue:22

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Carmustine; Chemotherapy, Adjuvant; Dacarbazine;

2005
Use of magnetic resonance imaging to assess blood-brain/blood-glioma barrier opening during conformal radiotherapy.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2005, Jun-20, Volume: 23, Issue:18

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Blood-Brain Barrier; Brain Neoplasms; Carboxymethylc

2005
Use of magnetic resonance imaging to assess blood-brain/blood-glioma barrier opening during conformal radiotherapy.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2005, Jun-20, Volume: 23, Issue:18

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Blood-Brain Barrier; Brain Neoplasms; Carboxymethylc

2005
Use of magnetic resonance imaging to assess blood-brain/blood-glioma barrier opening during conformal radiotherapy.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2005, Jun-20, Volume: 23, Issue:18

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Blood-Brain Barrier; Brain Neoplasms; Carboxymethylc

2005
Maintenance of fertility following treatment with temozolomide for a high grade astrocytoma.
    Journal of neuro-oncology, 2005, Volume: 73, Issue:2

    Topics: Adult; Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neoplasms; Dacarbazine; Fertility; Huma

2005
Maintenance of fertility following treatment with temozolomide for a high grade astrocytoma.
    Journal of neuro-oncology, 2005, Volume: 73, Issue:2

    Topics: Adult; Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neoplasms; Dacarbazine; Fertility; Huma

2005
Maintenance of fertility following treatment with temozolomide for a high grade astrocytoma.
    Journal of neuro-oncology, 2005, Volume: 73, Issue:2

    Topics: Adult; Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neoplasms; Dacarbazine; Fertility; Huma

2005
[Temozolomide in patients with a glioblastoma multiforme: new developments].
    Nederlands tijdschrift voor geneeskunde, 2005, Jun-18, Volume: 149, Issue:25

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant; Dacarbazine; Glioblastom

2005
[Temozolomide in patients with a glioblastoma multiforme: new developments].
    Nederlands tijdschrift voor geneeskunde, 2005, Jun-18, Volume: 149, Issue:25

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant; Dacarbazine; Glioblastom

2005
[Temozolomide in patients with a glioblastoma multiforme: new developments].
    Nederlands tijdschrift voor geneeskunde, 2005, Jun-18, Volume: 149, Issue:25

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant; Dacarbazine; Glioblastom

2005
[Favourable result for temozolomide in recurrent high-grade glioma].
    Nederlands tijdschrift voor geneeskunde, 2005, Jun-18, Volume: 149, Issue:25

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Disease Progression; F

2005
[Favourable result for temozolomide in recurrent high-grade glioma].
    Nederlands tijdschrift voor geneeskunde, 2005, Jun-18, Volume: 149, Issue:25

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Disease Progression; F

2005
[Favourable result for temozolomide in recurrent high-grade glioma].
    Nederlands tijdschrift voor geneeskunde, 2005, Jun-18, Volume: 149, Issue:25

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Disease Progression; F

2005
Modeling antitumor activity in xenograft tumor treatment.
    Biometrical journal. Biometrische Zeitschrift, 2005, Volume: 47, Issue:3

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Camptothecin; Computer Sim

2005
Modeling antitumor activity in xenograft tumor treatment.
    Biometrical journal. Biometrische Zeitschrift, 2005, Volume: 47, Issue:3

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Camptothecin; Computer Sim

2005
Modeling antitumor activity in xenograft tumor treatment.
    Biometrical journal. Biometrische Zeitschrift, 2005, Volume: 47, Issue:3

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Camptothecin; Computer Sim

2005
Economic evaluation of temozolomide in the treatment of recurrent glioblastoma multiforme.
    PharmacoEconomics, 2005, Volume: 23, Issue:8

    Topics: Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms;

2005
Economic evaluation of temozolomide in the treatment of recurrent glioblastoma multiforme.
    PharmacoEconomics, 2005, Volume: 23, Issue:8

    Topics: Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms;

2005
Economic evaluation of temozolomide in the treatment of recurrent glioblastoma multiforme.
    PharmacoEconomics, 2005, Volume: 23, Issue:8

    Topics: Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms;

2005
Perifosine inhibits multiple signaling pathways in glial progenitors and cooperates with temozolomide to arrest cell proliferation in gliomas in vivo.
    Cancer research, 2005, Aug-15, Volume: 65, Issue:16

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; CDC2-CDC28 Kinases; Cell G

2005
Perifosine inhibits multiple signaling pathways in glial progenitors and cooperates with temozolomide to arrest cell proliferation in gliomas in vivo.
    Cancer research, 2005, Aug-15, Volume: 65, Issue:16

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; CDC2-CDC28 Kinases; Cell G

2005
Perifosine inhibits multiple signaling pathways in glial progenitors and cooperates with temozolomide to arrest cell proliferation in gliomas in vivo.
    Cancer research, 2005, Aug-15, Volume: 65, Issue:16

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; CDC2-CDC28 Kinases; Cell G

2005
Current therapies for glioblastoma.
    Clinical advances in hematology & oncology : H&O, 2004, Volume: 2, Issue:9

    Topics: Antineoplastic Agents; Brain Neoplasms; Clinical Trials as Topic; Cranial Irradiation; Craniotomy; D

2004
Current therapies for glioblastoma.
    Clinical advances in hematology & oncology : H&O, 2004, Volume: 2, Issue:9

    Topics: Antineoplastic Agents; Brain Neoplasms; Clinical Trials as Topic; Cranial Irradiation; Craniotomy; D

2004
Current therapies for glioblastoma.
    Clinical advances in hematology & oncology : H&O, 2004, Volume: 2, Issue:9

    Topics: Antineoplastic Agents; Brain Neoplasms; Clinical Trials as Topic; Cranial Irradiation; Craniotomy; D

2004
Simulating chemotherapeutic schemes in the individualized treatment context: the paradigm of glioblastoma multiforme treated by temozolomide in vivo.
    Computers in biology and medicine, 2006, Volume: 36, Issue:11

    Topics: Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cell Cycle; Cell Division; Computer G

2006
Simulating chemotherapeutic schemes in the individualized treatment context: the paradigm of glioblastoma multiforme treated by temozolomide in vivo.
    Computers in biology and medicine, 2006, Volume: 36, Issue:11

    Topics: Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cell Cycle; Cell Division; Computer G

2006
Simulating chemotherapeutic schemes in the individualized treatment context: the paradigm of glioblastoma multiforme treated by temozolomide in vivo.
    Computers in biology and medicine, 2006, Volume: 36, Issue:11

    Topics: Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cell Cycle; Cell Division; Computer G

2006
Patients with high-grade gliomas harboring deletions of chromosomes 9p and 10q benefit from temozolomide treatment.
    Neoplasia (New York, N.Y.), 2005, Volume: 7, Issue:10

    Topics: Adult; Age Factors; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chromosome Deletion; C

2005
Patients with high-grade gliomas harboring deletions of chromosomes 9p and 10q benefit from temozolomide treatment.
    Neoplasia (New York, N.Y.), 2005, Volume: 7, Issue:10

    Topics: Adult; Age Factors; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chromosome Deletion; C

2005
Patients with high-grade gliomas harboring deletions of chromosomes 9p and 10q benefit from temozolomide treatment.
    Neoplasia (New York, N.Y.), 2005, Volume: 7, Issue:10

    Topics: Adult; Age Factors; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chromosome Deletion; C

2005
Does addition of temozolomide to whole brain radiotherapy improve outcome in patients with brain metastases?
    Nature clinical practice. Oncology, 2005, Volume: 2, Issue:4

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Clinical Trials as Topic; Combined Modality Ther

2005
Does addition of temozolomide to whole brain radiotherapy improve outcome in patients with brain metastases?
    Nature clinical practice. Oncology, 2005, Volume: 2, Issue:4

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Clinical Trials as Topic; Combined Modality Ther

2005
Does addition of temozolomide to whole brain radiotherapy improve outcome in patients with brain metastases?
    Nature clinical practice. Oncology, 2005, Volume: 2, Issue:4

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Clinical Trials as Topic; Combined Modality Ther

2005
Salvage temozolomide for prior temozolomide responders.
    Cancer, 2005, Dec-01, Volume: 104, Issue:11

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neoplasms; Dacarbazine; Female; G

2005
Salvage temozolomide for prior temozolomide responders.
    Cancer, 2005, Dec-01, Volume: 104, Issue:11

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neoplasms; Dacarbazine; Female; G

2005
Salvage temozolomide for prior temozolomide responders.
    Cancer, 2005, Dec-01, Volume: 104, Issue:11

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neoplasms; Dacarbazine; Female; G

2005
Efficiency, quality and bureaucracy: not always in the same bag!!
    European journal of cancer (Oxford, England : 1990), 2005, Volume: 41, Issue:14

    Topics: Antineoplastic Agents, Alkylating; Biomedical Research; Brain Neoplasms; Clinical Trials as Topic; D

2005
Efficiency, quality and bureaucracy: not always in the same bag!!
    European journal of cancer (Oxford, England : 1990), 2005, Volume: 41, Issue:14

    Topics: Antineoplastic Agents, Alkylating; Biomedical Research; Brain Neoplasms; Clinical Trials as Topic; D

2005
Efficiency, quality and bureaucracy: not always in the same bag!!
    European journal of cancer (Oxford, England : 1990), 2005, Volume: 41, Issue:14

    Topics: Antineoplastic Agents, Alkylating; Biomedical Research; Brain Neoplasms; Clinical Trials as Topic; D

2005
10 questions about temozolomide and the treatment of brain tumors.
    The neurologist, 2005, Volume: 11, Issue:6

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Humans; Temozolomide

2005
10 questions about temozolomide and the treatment of brain tumors.
    The neurologist, 2005, Volume: 11, Issue:6

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Humans; Temozolomide

2005
10 questions about temozolomide and the treatment of brain tumors.
    The neurologist, 2005, Volume: 11, Issue:6

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Humans; Temozolomide

2005
Poly(ADP-ribose) glycohydrolase inhibitor as chemosensitiser of malignant melanoma for temozolomide.
    European journal of cancer (Oxford, England : 1990), 2005, Volume: 41, Issue:18

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Cell Line, Tumor; Cell Pro

2005
Poly(ADP-ribose) glycohydrolase inhibitor as chemosensitiser of malignant melanoma for temozolomide.
    European journal of cancer (Oxford, England : 1990), 2005, Volume: 41, Issue:18

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Cell Line, Tumor; Cell Pro

2005
Poly(ADP-ribose) glycohydrolase inhibitor as chemosensitiser of malignant melanoma for temozolomide.
    European journal of cancer (Oxford, England : 1990), 2005, Volume: 41, Issue:18

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Cell Line, Tumor; Cell Pro

2005
Higher dosing of temozolomide? Regression of an anaplastic oligoastrocytoma over more than three years.
    Journal of neuro-oncology, 2006, Volume: 77, Issue:2

    Topics: Antineoplastic Agents, Alkylating; Astrocytoma; Bone Marrow; Brain Neoplasms; Dacarbazine; Drug Over

2006
Higher dosing of temozolomide? Regression of an anaplastic oligoastrocytoma over more than three years.
    Journal of neuro-oncology, 2006, Volume: 77, Issue:2

    Topics: Antineoplastic Agents, Alkylating; Astrocytoma; Bone Marrow; Brain Neoplasms; Dacarbazine; Drug Over

2006
Higher dosing of temozolomide? Regression of an anaplastic oligoastrocytoma over more than three years.
    Journal of neuro-oncology, 2006, Volume: 77, Issue:2

    Topics: Antineoplastic Agents, Alkylating; Astrocytoma; Bone Marrow; Brain Neoplasms; Dacarbazine; Drug Over

2006
A congenital brain tumor associated with assisted in vitro fertilization. Case report.
    Journal of neurosurgery, 2005, Volume: 103, Issue:5 Suppl

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Astrocytoma; Brain Neoplasms; Dacarbazine; Fe

2005
A congenital brain tumor associated with assisted in vitro fertilization. Case report.
    Journal of neurosurgery, 2005, Volume: 103, Issue:5 Suppl

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Astrocytoma; Brain Neoplasms; Dacarbazine; Fe

2005
A congenital brain tumor associated with assisted in vitro fertilization. Case report.
    Journal of neurosurgery, 2005, Volume: 103, Issue:5 Suppl

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Astrocytoma; Brain Neoplasms; Dacarbazine; Fe

2005
Combination treatment with temozolomide and thalidomide inhibits tumor growth and angiogenesis in an orthotopic glioma model.
    International journal of oncology, 2006, Volume: 28, Issue:1

    Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cel

2006
Combination treatment with temozolomide and thalidomide inhibits tumor growth and angiogenesis in an orthotopic glioma model.
    International journal of oncology, 2006, Volume: 28, Issue:1

    Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cel

2006
Combination treatment with temozolomide and thalidomide inhibits tumor growth and angiogenesis in an orthotopic glioma model.
    International journal of oncology, 2006, Volume: 28, Issue:1

    Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cel

2006
Combination celecoxib and temozolomide in C6 rat glioma orthotopic model.
    Oncology reports, 2006, Volume: 15, Issue:1

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Celecoxib; Cyclooxygenase

2006
Combination celecoxib and temozolomide in C6 rat glioma orthotopic model.
    Oncology reports, 2006, Volume: 15, Issue:1

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Celecoxib; Cyclooxygenase

2006
Combination celecoxib and temozolomide in C6 rat glioma orthotopic model.
    Oncology reports, 2006, Volume: 15, Issue:1

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Celecoxib; Cyclooxygenase

2006
Chemotherapy for glioblastoma multiforme (GBM).
    Surgical neurology, 2006, Volume: 65, Issue:2

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Glioblastoma; Humans; Temozolomide

2006
Chemotherapy for glioblastoma multiforme (GBM).
    Surgical neurology, 2006, Volume: 65, Issue:2

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Glioblastoma; Humans; Temozolomide

2006
Chemotherapy for glioblastoma multiforme (GBM).
    Surgical neurology, 2006, Volume: 65, Issue:2

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Glioblastoma; Humans; Temozolomide

2006
Biochemotherapy with temozolomide, cisplatin, vinblastine, subcutaneous interleukin-2 and interferon-alpha in patients with metastatic melanoma.
    Melanoma research, 2006, Volume: 16, Issue:1

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Cisplatin; Combined Mo

2006
Biochemotherapy with temozolomide, cisplatin, vinblastine, subcutaneous interleukin-2 and interferon-alpha in patients with metastatic melanoma.
    Melanoma research, 2006, Volume: 16, Issue:1

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Cisplatin; Combined Mo

2006
Biochemotherapy with temozolomide, cisplatin, vinblastine, subcutaneous interleukin-2 and interferon-alpha in patients with metastatic melanoma.
    Melanoma research, 2006, Volume: 16, Issue:1

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Cisplatin; Combined Mo

2006
A case report of a recurrent intracranial ependymoma treated with temozolomide in remission 10 years after completing chemotherapy.
    American journal of clinical oncology, 2006, Volume: 29, Issue:1

    Topics: Adult; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Ependymoma; Female; Humans;

2006
A case report of a recurrent intracranial ependymoma treated with temozolomide in remission 10 years after completing chemotherapy.
    American journal of clinical oncology, 2006, Volume: 29, Issue:1

    Topics: Adult; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Ependymoma; Female; Humans;

2006
A case report of a recurrent intracranial ependymoma treated with temozolomide in remission 10 years after completing chemotherapy.
    American journal of clinical oncology, 2006, Volume: 29, Issue:1

    Topics: Adult; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Ependymoma; Female; Humans;

2006
Progressive low-grade oligodendrogliomas: response to temozolomide and correlation between genetic profile and O6-methylguanine DNA methyltransferase protein expression.
    Cancer, 2006, Apr-15, Volume: 106, Issue:8

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chromosomes, Human, Pai

2006
Progressive low-grade oligodendrogliomas: response to temozolomide and correlation between genetic profile and O6-methylguanine DNA methyltransferase protein expression.
    Cancer, 2006, Apr-15, Volume: 106, Issue:8

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chromosomes, Human, Pai

2006
Progressive low-grade oligodendrogliomas: response to temozolomide and correlation between genetic profile and O6-methylguanine DNA methyltransferase protein expression.
    Cancer, 2006, Apr-15, Volume: 106, Issue:8

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chromosomes, Human, Pai

2006
Antiangiogenic agent, thalidomide increases the antitumor effect of single high dose irradiation (gamma knife radiosurgery) in the rat orthotopic glioma model.
    Oncology reports, 2006, Volume: 15, Issue:5

    Topics: Angiogenesis Inhibitors; Animals; Apoptosis; Brain Neoplasms; Cell Proliferation; Combined Modality

2006
Antiangiogenic agent, thalidomide increases the antitumor effect of single high dose irradiation (gamma knife radiosurgery) in the rat orthotopic glioma model.
    Oncology reports, 2006, Volume: 15, Issue:5

    Topics: Angiogenesis Inhibitors; Animals; Apoptosis; Brain Neoplasms; Cell Proliferation; Combined Modality

2006
Antiangiogenic agent, thalidomide increases the antitumor effect of single high dose irradiation (gamma knife radiosurgery) in the rat orthotopic glioma model.
    Oncology reports, 2006, Volume: 15, Issue:5

    Topics: Angiogenesis Inhibitors; Animals; Apoptosis; Brain Neoplasms; Cell Proliferation; Combined Modality

2006
MGMT promoter methylation correlates with survival benefit and sensitivity to temozolomide in pediatric glioblastoma.
    Pediatric blood & cancer, 2007, Volume: 48, Issue:4

    Topics: Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms;

2007
MGMT promoter methylation correlates with survival benefit and sensitivity to temozolomide in pediatric glioblastoma.
    Pediatric blood & cancer, 2007, Volume: 48, Issue:4

    Topics: Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms;

2007
MGMT promoter methylation correlates with survival benefit and sensitivity to temozolomide in pediatric glioblastoma.
    Pediatric blood & cancer, 2007, Volume: 48, Issue:4

    Topics: Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms;

2007
MGMT promoter methylation correlates with survival benefit and sensitivity to temozolomide in pediatric glioblastoma.
    Pediatric blood & cancer, 2007, Volume: 48, Issue:4

    Topics: Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms;

2007
MGMT promoter methylation correlates with survival benefit and sensitivity to temozolomide in pediatric glioblastoma.
    Pediatric blood & cancer, 2007, Volume: 48, Issue:4

    Topics: Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms;

2007
MGMT promoter methylation correlates with survival benefit and sensitivity to temozolomide in pediatric glioblastoma.
    Pediatric blood & cancer, 2007, Volume: 48, Issue:4

    Topics: Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms;

2007
MGMT promoter methylation correlates with survival benefit and sensitivity to temozolomide in pediatric glioblastoma.
    Pediatric blood & cancer, 2007, Volume: 48, Issue:4

    Topics: Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms;

2007
MGMT promoter methylation correlates with survival benefit and sensitivity to temozolomide in pediatric glioblastoma.
    Pediatric blood & cancer, 2007, Volume: 48, Issue:4

    Topics: Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms;

2007
MGMT promoter methylation correlates with survival benefit and sensitivity to temozolomide in pediatric glioblastoma.
    Pediatric blood & cancer, 2007, Volume: 48, Issue:4

    Topics: Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms;

2007
MGMT promoter methylation correlates with survival benefit and sensitivity to temozolomide in pediatric glioblastoma.
    Pediatric blood & cancer, 2007, Volume: 48, Issue:4

    Topics: Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms;

2007
MGMT promoter methylation correlates with survival benefit and sensitivity to temozolomide in pediatric glioblastoma.
    Pediatric blood & cancer, 2007, Volume: 48, Issue:4

    Topics: Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms;

2007
MGMT promoter methylation correlates with survival benefit and sensitivity to temozolomide in pediatric glioblastoma.
    Pediatric blood & cancer, 2007, Volume: 48, Issue:4

    Topics: Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms;

2007
A hypermutation phenotype and somatic MSH6 mutations in recurrent human malignant gliomas after alkylator chemotherapy.
    Cancer research, 2006, Apr-15, Volume: 66, Issue:8

    Topics: Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; DNA-Binding Proteins; Female;

2006
A hypermutation phenotype and somatic MSH6 mutations in recurrent human malignant gliomas after alkylator chemotherapy.
    Cancer research, 2006, Apr-15, Volume: 66, Issue:8

    Topics: Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; DNA-Binding Proteins; Female;

2006
A hypermutation phenotype and somatic MSH6 mutations in recurrent human malignant gliomas after alkylator chemotherapy.
    Cancer research, 2006, Apr-15, Volume: 66, Issue:8

    Topics: Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; DNA-Binding Proteins; Female;

2006
Radical surgery after chemotherapy: a new therapeutic strategy to envision in grade II glioma.
    Journal of neuro-oncology, 2006, Volume: 80, Issue:2

    Topics: Adult; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Corpus Callosu

2006
Radical surgery after chemotherapy: a new therapeutic strategy to envision in grade II glioma.
    Journal of neuro-oncology, 2006, Volume: 80, Issue:2

    Topics: Adult; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Corpus Callosu

2006
Radical surgery after chemotherapy: a new therapeutic strategy to envision in grade II glioma.
    Journal of neuro-oncology, 2006, Volume: 80, Issue:2

    Topics: Adult; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Corpus Callosu

2006
Complications of a temozolomide overdose: a case report.
    Journal of neuro-oncology, 2006, Volume: 80, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Bacterial Infections; Brain Neoplasms; Combined Modality Therapy;

2006
Complications of a temozolomide overdose: a case report.
    Journal of neuro-oncology, 2006, Volume: 80, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Bacterial Infections; Brain Neoplasms; Combined Modality Therapy;

2006
Complications of a temozolomide overdose: a case report.
    Journal of neuro-oncology, 2006, Volume: 80, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Bacterial Infections; Brain Neoplasms; Combined Modality Therapy;

2006
Whole brain irradiation and temozolomide based chemotherapy in melanoma brain metastases.
    Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico, 2006, Volume: 8, Issue:4

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Brai

2006
Whole brain irradiation and temozolomide based chemotherapy in melanoma brain metastases.
    Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico, 2006, Volume: 8, Issue:4

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Brai

2006
Whole brain irradiation and temozolomide based chemotherapy in melanoma brain metastases.
    Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico, 2006, Volume: 8, Issue:4

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Brai

2006
Enhancement of glioblastoma cell killing by combination treatment with temozolomide and tamoxifen or hypericin.
    Neurosurgical focus, 2006, Apr-15, Volume: 20, Issue:4

    Topics: Animals; Anthracenes; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Antineoplastic Combi

2006
Enhancement of glioblastoma cell killing by combination treatment with temozolomide and tamoxifen or hypericin.
    Neurosurgical focus, 2006, Apr-15, Volume: 20, Issue:4

    Topics: Animals; Anthracenes; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Antineoplastic Combi

2006
Enhancement of glioblastoma cell killing by combination treatment with temozolomide and tamoxifen or hypericin.
    Neurosurgical focus, 2006, Apr-15, Volume: 20, Issue:4

    Topics: Animals; Anthracenes; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Antineoplastic Combi

2006
Listeria brain abscess, Pneumocystis pneumonia and Kaposi's sarcoma after temozolomide.
    Nature clinical practice. Oncology, 2006, Volume: 3, Issue:6

    Topics: Antineoplastic Agents, Alkylating; Brain Abscess; Brain Neoplasms; Dacarbazine; Glioblastoma; Humans

2006
Listeria brain abscess, Pneumocystis pneumonia and Kaposi's sarcoma after temozolomide.
    Nature clinical practice. Oncology, 2006, Volume: 3, Issue:6

    Topics: Antineoplastic Agents, Alkylating; Brain Abscess; Brain Neoplasms; Dacarbazine; Glioblastoma; Humans

2006
Listeria brain abscess, Pneumocystis pneumonia and Kaposi's sarcoma after temozolomide.
    Nature clinical practice. Oncology, 2006, Volume: 3, Issue:6

    Topics: Antineoplastic Agents, Alkylating; Brain Abscess; Brain Neoplasms; Dacarbazine; Glioblastoma; Humans

2006
Apoptosis in malignant glioma cells triggered by the temozolomide-induced DNA lesion O6-methylguanine.
    Oncogene, 2007, Jan-11, Volume: 26, Issue:2

    Topics: Antineoplastic Agents, Alkylating; Apoptosis; Blotting, Western; Brain Neoplasms; Caspases; Cell Cyc

2007
Apoptosis in malignant glioma cells triggered by the temozolomide-induced DNA lesion O6-methylguanine.
    Oncogene, 2007, Jan-11, Volume: 26, Issue:2

    Topics: Antineoplastic Agents, Alkylating; Apoptosis; Blotting, Western; Brain Neoplasms; Caspases; Cell Cyc

2007
Apoptosis in malignant glioma cells triggered by the temozolomide-induced DNA lesion O6-methylguanine.
    Oncogene, 2007, Jan-11, Volume: 26, Issue:2

    Topics: Antineoplastic Agents, Alkylating; Apoptosis; Blotting, Western; Brain Neoplasms; Caspases; Cell Cyc

2007
Irradiation and hypoxia promote homing of haematopoietic progenitor cells towards gliomas by TGF-beta-dependent HIF-1alpha-mediated induction of CXCL12.
    Brain : a journal of neurology, 2006, Volume: 129, Issue:Pt 9

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain; Brain Neoplasms; Cell Hypoxia; Cell Line, Tumor;

2006
Irradiation and hypoxia promote homing of haematopoietic progenitor cells towards gliomas by TGF-beta-dependent HIF-1alpha-mediated induction of CXCL12.
    Brain : a journal of neurology, 2006, Volume: 129, Issue:Pt 9

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain; Brain Neoplasms; Cell Hypoxia; Cell Line, Tumor;

2006
Irradiation and hypoxia promote homing of haematopoietic progenitor cells towards gliomas by TGF-beta-dependent HIF-1alpha-mediated induction of CXCL12.
    Brain : a journal of neurology, 2006, Volume: 129, Issue:Pt 9

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain; Brain Neoplasms; Cell Hypoxia; Cell Line, Tumor;

2006
Early change in glucose metabolic rate measured using FDG-PET in patients with high-grade glioma predicts response to temozolomide but not temozolomide plus radiotherapy.
    International journal of radiation oncology, biology, physics, 2006, Oct-01, Volume: 66, Issue:2

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Brain; Brain Neoplasms; Combined Modalit

2006
Early change in glucose metabolic rate measured using FDG-PET in patients with high-grade glioma predicts response to temozolomide but not temozolomide plus radiotherapy.
    International journal of radiation oncology, biology, physics, 2006, Oct-01, Volume: 66, Issue:2

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Brain; Brain Neoplasms; Combined Modalit

2006
Early change in glucose metabolic rate measured using FDG-PET in patients with high-grade glioma predicts response to temozolomide but not temozolomide plus radiotherapy.
    International journal of radiation oncology, biology, physics, 2006, Oct-01, Volume: 66, Issue:2

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Brain; Brain Neoplasms; Combined Modalit

2006
Temozolomide treatment of refractory epilepsy in a patient with an oligodendroglioma.
    Epilepsia, 2006, Volume: 47, Issue:7

    Topics: Adult; Anticonvulsants; Antineoplastic Agents, Alkylating; Brain Neoplasms; Comorbidity; Dacarbazine

2006
Temozolomide treatment of refractory epilepsy in a patient with an oligodendroglioma.
    Epilepsia, 2006, Volume: 47, Issue:7

    Topics: Adult; Anticonvulsants; Antineoplastic Agents, Alkylating; Brain Neoplasms; Comorbidity; Dacarbazine

2006
Temozolomide treatment of refractory epilepsy in a patient with an oligodendroglioma.
    Epilepsia, 2006, Volume: 47, Issue:7

    Topics: Adult; Anticonvulsants; Antineoplastic Agents, Alkylating; Brain Neoplasms; Comorbidity; Dacarbazine

2006
Is protracted low-dose temozolomide feasible in glioma patients?
    Neurology, 2006, Aug-08, Volume: 67, Issue:3

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Central Nervous System Neoplasms; Combined Modal

2006
Is protracted low-dose temozolomide feasible in glioma patients?
    Neurology, 2006, Aug-08, Volume: 67, Issue:3

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Central Nervous System Neoplasms; Combined Modal

2006
Is protracted low-dose temozolomide feasible in glioma patients?
    Neurology, 2006, Aug-08, Volume: 67, Issue:3

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Central Nervous System Neoplasms; Combined Modal

2006
1p/19q loss within oligodendroglioma is predictive for response to first line temozolomide but not to salvage treatment.
    European journal of cancer (Oxford, England : 1990), 2006, Volume: 42, Issue:15

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chromosomes, Human, Pair 1; Chromosomes, Human,

2006
1p/19q loss within oligodendroglioma is predictive for response to first line temozolomide but not to salvage treatment.
    European journal of cancer (Oxford, England : 1990), 2006, Volume: 42, Issue:15

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chromosomes, Human, Pair 1; Chromosomes, Human,

2006
1p/19q loss within oligodendroglioma is predictive for response to first line temozolomide but not to salvage treatment.
    European journal of cancer (Oxford, England : 1990), 2006, Volume: 42, Issue:15

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chromosomes, Human, Pair 1; Chromosomes, Human,

2006
1p/19q loss within oligodendroglioma is predictive for response to first line temozolomide but not to salvage treatment.
    European journal of cancer (Oxford, England : 1990), 2006, Volume: 42, Issue:15

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chromosomes, Human, Pair 1; Chromosomes, Human,

2006
1p/19q loss within oligodendroglioma is predictive for response to first line temozolomide but not to salvage treatment.
    European journal of cancer (Oxford, England : 1990), 2006, Volume: 42, Issue:15

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chromosomes, Human, Pair 1; Chromosomes, Human,

2006
1p/19q loss within oligodendroglioma is predictive for response to first line temozolomide but not to salvage treatment.
    European journal of cancer (Oxford, England : 1990), 2006, Volume: 42, Issue:15

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chromosomes, Human, Pair 1; Chromosomes, Human,

2006
1p/19q loss within oligodendroglioma is predictive for response to first line temozolomide but not to salvage treatment.
    European journal of cancer (Oxford, England : 1990), 2006, Volume: 42, Issue:15

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chromosomes, Human, Pair 1; Chromosomes, Human,

2006
1p/19q loss within oligodendroglioma is predictive for response to first line temozolomide but not to salvage treatment.
    European journal of cancer (Oxford, England : 1990), 2006, Volume: 42, Issue:15

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chromosomes, Human, Pair 1; Chromosomes, Human,

2006
1p/19q loss within oligodendroglioma is predictive for response to first line temozolomide but not to salvage treatment.
    European journal of cancer (Oxford, England : 1990), 2006, Volume: 42, Issue:15

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chromosomes, Human, Pair 1; Chromosomes, Human,

2006
1p/19q loss within oligodendroglioma is predictive for response to first line temozolomide but not to salvage treatment.
    European journal of cancer (Oxford, England : 1990), 2006, Volume: 42, Issue:15

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chromosomes, Human, Pair 1; Chromosomes, Human,

2006
1p/19q loss within oligodendroglioma is predictive for response to first line temozolomide but not to salvage treatment.
    European journal of cancer (Oxford, England : 1990), 2006, Volume: 42, Issue:15

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chromosomes, Human, Pair 1; Chromosomes, Human,

2006
1p/19q loss within oligodendroglioma is predictive for response to first line temozolomide but not to salvage treatment.
    European journal of cancer (Oxford, England : 1990), 2006, Volume: 42, Issue:15

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chromosomes, Human, Pair 1; Chromosomes, Human,

2006
Gliomatosis cerebri treatment in 11 elderly patients.
    Journal of experimental & clinical cancer research : CR, 2006, Volume: 25, Issue:2

    Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Combined M

2006
Gliomatosis cerebri treatment in 11 elderly patients.
    Journal of experimental & clinical cancer research : CR, 2006, Volume: 25, Issue:2

    Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Combined M

2006
Gliomatosis cerebri treatment in 11 elderly patients.
    Journal of experimental & clinical cancer research : CR, 2006, Volume: 25, Issue:2

    Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Combined M

2006
Re-evaluation of the cost effectiveness of temozolomide for malignant gliomas in British Columbia.
    Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners, 2006, Volume: 12, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; British Columbia

2006
Re-evaluation of the cost effectiveness of temozolomide for malignant gliomas in British Columbia.
    Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners, 2006, Volume: 12, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; British Columbia

2006
Re-evaluation of the cost effectiveness of temozolomide for malignant gliomas in British Columbia.
    Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners, 2006, Volume: 12, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; British Columbia

2006
A pilot study of primary temozolomide chemotherapy and deferred radiotherapy in elderly patients with glioblastoma.
    Journal of neuro-oncology, 2007, Volume: 82, Issue:2

    Topics: Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Female; Gl

2007
A pilot study of primary temozolomide chemotherapy and deferred radiotherapy in elderly patients with glioblastoma.
    Journal of neuro-oncology, 2007, Volume: 82, Issue:2

    Topics: Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Female; Gl

2007
A pilot study of primary temozolomide chemotherapy and deferred radiotherapy in elderly patients with glioblastoma.
    Journal of neuro-oncology, 2007, Volume: 82, Issue:2

    Topics: Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Female; Gl

2007
Development of luciferase tagged brain tumour models in mice for chemotherapy intervention studies.
    European journal of cancer (Oxford, England : 1990), 2006, Volume: 42, Issue:18

    Topics: Animals; Antineoplastic Agents, Alkylating; Blood-Brain Barrier; Brain Neoplasms; Cell Division; Cel

2006
Development of luciferase tagged brain tumour models in mice for chemotherapy intervention studies.
    European journal of cancer (Oxford, England : 1990), 2006, Volume: 42, Issue:18

    Topics: Animals; Antineoplastic Agents, Alkylating; Blood-Brain Barrier; Brain Neoplasms; Cell Division; Cel

2006
Development of luciferase tagged brain tumour models in mice for chemotherapy intervention studies.
    European journal of cancer (Oxford, England : 1990), 2006, Volume: 42, Issue:18

    Topics: Animals; Antineoplastic Agents, Alkylating; Blood-Brain Barrier; Brain Neoplasms; Cell Division; Cel

2006
Local intracerebral administration of O(6)-benzylguanine combined with systemic chemotherapy with temozolomide of a patient suffering from a recurrent glioblastoma.
    Journal of neuro-oncology, 2007, Volume: 82, Issue:1

    Topics: Adult; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Brain Neop

2007
Local intracerebral administration of O(6)-benzylguanine combined with systemic chemotherapy with temozolomide of a patient suffering from a recurrent glioblastoma.
    Journal of neuro-oncology, 2007, Volume: 82, Issue:1

    Topics: Adult; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Brain Neop

2007
Local intracerebral administration of O(6)-benzylguanine combined with systemic chemotherapy with temozolomide of a patient suffering from a recurrent glioblastoma.
    Journal of neuro-oncology, 2007, Volume: 82, Issue:1

    Topics: Adult; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Brain Neop

2007
Ganglioglioma occurring with glioblastoma multiforme: separate lesions or the same lesion?
    Clinical neurology and neurosurgery, 2007, Volume: 109, Issue:2

    Topics: Antineoplastic Agents, Alkylating; Astrocytes; Biomarkers, Tumor; Brain Neoplasms; Chemotherapy, Adj

2007
Ganglioglioma occurring with glioblastoma multiforme: separate lesions or the same lesion?
    Clinical neurology and neurosurgery, 2007, Volume: 109, Issue:2

    Topics: Antineoplastic Agents, Alkylating; Astrocytes; Biomarkers, Tumor; Brain Neoplasms; Chemotherapy, Adj

2007
Ganglioglioma occurring with glioblastoma multiforme: separate lesions or the same lesion?
    Clinical neurology and neurosurgery, 2007, Volume: 109, Issue:2

    Topics: Antineoplastic Agents, Alkylating; Astrocytes; Biomarkers, Tumor; Brain Neoplasms; Chemotherapy, Adj

2007
Spanish co-operative group of Medical Neuro-oncology (GENOM).
    Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico, 2006, Volume: 8, Issue:10

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Glioma;

2006
Spanish co-operative group of Medical Neuro-oncology (GENOM).
    Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico, 2006, Volume: 8, Issue:10

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Glioma;

2006
Spanish co-operative group of Medical Neuro-oncology (GENOM).
    Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico, 2006, Volume: 8, Issue:10

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Glioma;

2006
Toxicity and efficacy of protracted low dose temozolomide for the treatment of low grade gliomas.
    Journal of neuro-oncology, 2007, Volume: 82, Issue:3

    Topics: Adult; Aged; Antineoplastic Agents; Brain Neoplasms; Dacarbazine; Disease-Free Survival; Female; Gli

2007
Toxicity and efficacy of protracted low dose temozolomide for the treatment of low grade gliomas.
    Journal of neuro-oncology, 2007, Volume: 82, Issue:3

    Topics: Adult; Aged; Antineoplastic Agents; Brain Neoplasms; Dacarbazine; Disease-Free Survival; Female; Gli

2007
Toxicity and efficacy of protracted low dose temozolomide for the treatment of low grade gliomas.
    Journal of neuro-oncology, 2007, Volume: 82, Issue:3

    Topics: Adult; Aged; Antineoplastic Agents; Brain Neoplasms; Dacarbazine; Disease-Free Survival; Female; Gli

2007
Potentiation of antiglioma effect with combined temozolomide and interferon-beta.
    Oncology reports, 2006, Volume: 16, Issue:6

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Brain Neoplasms; Cell Line, Tumo

2006
Potentiation of antiglioma effect with combined temozolomide and interferon-beta.
    Oncology reports, 2006, Volume: 16, Issue:6

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Brain Neoplasms; Cell Line, Tumo

2006
Potentiation of antiglioma effect with combined temozolomide and interferon-beta.
    Oncology reports, 2006, Volume: 16, Issue:6

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Brain Neoplasms; Cell Line, Tumo

2006
The impact of thrombocytopenia from temozolomide and radiation in newly diagnosed adults with high-grade gliomas.
    Neuro-oncology, 2007, Volume: 9, Issue:1

    Topics: Adult; Aged; Anemia; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy;

2007
The impact of thrombocytopenia from temozolomide and radiation in newly diagnosed adults with high-grade gliomas.
    Neuro-oncology, 2007, Volume: 9, Issue:1

    Topics: Adult; Aged; Anemia; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy;

2007
The impact of thrombocytopenia from temozolomide and radiation in newly diagnosed adults with high-grade gliomas.
    Neuro-oncology, 2007, Volume: 9, Issue:1

    Topics: Adult; Aged; Anemia; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy;

2007
Interindividual differences in anticancer drug cytotoxicity in primary human glioblastoma cells.
    Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie, 2007, Volume: 58, Issue:4

    Topics: Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Culture Techniques; Dacarbazine; Drug

2007
Interindividual differences in anticancer drug cytotoxicity in primary human glioblastoma cells.
    Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie, 2007, Volume: 58, Issue:4

    Topics: Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Culture Techniques; Dacarbazine; Drug

2007
Interindividual differences in anticancer drug cytotoxicity in primary human glioblastoma cells.
    Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie, 2007, Volume: 58, Issue:4

    Topics: Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Culture Techniques; Dacarbazine; Drug

2007
[Individualized chemotherapy based on drug sensitivity and resistance assay and MGMT protein expression for patients with malignant glioma--analysis of 42 cases].
    Ai zheng = Aizheng = Chinese journal of cancer, 2006, Volume: 25, Issue:12

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Astrocytoma; Brain Neoplasms; Chi

2006
[Individualized chemotherapy based on drug sensitivity and resistance assay and MGMT protein expression for patients with malignant glioma--analysis of 42 cases].
    Ai zheng = Aizheng = Chinese journal of cancer, 2006, Volume: 25, Issue:12

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Astrocytoma; Brain Neoplasms; Chi

2006
[Individualized chemotherapy based on drug sensitivity and resistance assay and MGMT protein expression for patients with malignant glioma--analysis of 42 cases].
    Ai zheng = Aizheng = Chinese journal of cancer, 2006, Volume: 25, Issue:12

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Astrocytoma; Brain Neoplasms; Chi

2006
[Recent advances in the medical treatment of glioma-temozolomide].
    No to shinkei = Brain and nerve, 2006, Volume: 58, Issue:12

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbaz

2006
[Recent advances in the medical treatment of glioma-temozolomide].
    No to shinkei = Brain and nerve, 2006, Volume: 58, Issue:12

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbaz

2006
[Recent advances in the medical treatment of glioma-temozolomide].
    No to shinkei = Brain and nerve, 2006, Volume: 58, Issue:12

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbaz

2006
The Fanconi anemia (FA) pathway confers glioma resistance to DNA alkylating agents.
    Journal of molecular medicine (Berlin, Germany), 2007, Volume: 85, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Carmustine; Cell Line, Tumor; Curcumin; Dacarbaz

2007
The Fanconi anemia (FA) pathway confers glioma resistance to DNA alkylating agents.
    Journal of molecular medicine (Berlin, Germany), 2007, Volume: 85, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Carmustine; Cell Line, Tumor; Curcumin; Dacarbaz

2007
The Fanconi anemia (FA) pathway confers glioma resistance to DNA alkylating agents.
    Journal of molecular medicine (Berlin, Germany), 2007, Volume: 85, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Carmustine; Cell Line, Tumor; Curcumin; Dacarbaz

2007
Salvage therapy for primary central nervous system lymphoma with (90)Y-Ibritumomab and Temozolomide.
    Journal of neuro-oncology, 2007, Volume: 83, Issue:3

    Topics: Aged; Antibodies, Monoclonal; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality

2007
Salvage therapy for primary central nervous system lymphoma with (90)Y-Ibritumomab and Temozolomide.
    Journal of neuro-oncology, 2007, Volume: 83, Issue:3

    Topics: Aged; Antibodies, Monoclonal; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality

2007
Salvage therapy for primary central nervous system lymphoma with (90)Y-Ibritumomab and Temozolomide.
    Journal of neuro-oncology, 2007, Volume: 83, Issue:3

    Topics: Aged; Antibodies, Monoclonal; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality

2007
Local delivery of temozolomide by biodegradable polymers is superior to oral administration in a rodent glioma model.
    Cancer chemotherapy and pharmacology, 2007, Volume: 60, Issue:5

    Topics: Administration, Oral; Animals; Antineoplastic Agents; Biocompatible Materials; Brain Neoplasms; Comb

2007
Local delivery of temozolomide by biodegradable polymers is superior to oral administration in a rodent glioma model.
    Cancer chemotherapy and pharmacology, 2007, Volume: 60, Issue:5

    Topics: Administration, Oral; Animals; Antineoplastic Agents; Biocompatible Materials; Brain Neoplasms; Comb

2007
Local delivery of temozolomide by biodegradable polymers is superior to oral administration in a rodent glioma model.
    Cancer chemotherapy and pharmacology, 2007, Volume: 60, Issue:5

    Topics: Administration, Oral; Animals; Antineoplastic Agents; Biocompatible Materials; Brain Neoplasms; Comb

2007
Preclinical pharmacokinetic and pharmacodynamic evaluation of metronomic and conventional temozolomide dosing regimens.
    The Journal of pharmacology and experimental therapeutics, 2007, Volume: 321, Issue:1

    Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Agents, Alkylating; Blotting, Western; Brain Neopla

2007
Preclinical pharmacokinetic and pharmacodynamic evaluation of metronomic and conventional temozolomide dosing regimens.
    The Journal of pharmacology and experimental therapeutics, 2007, Volume: 321, Issue:1

    Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Agents, Alkylating; Blotting, Western; Brain Neopla

2007
Preclinical pharmacokinetic and pharmacodynamic evaluation of metronomic and conventional temozolomide dosing regimens.
    The Journal of pharmacology and experimental therapeutics, 2007, Volume: 321, Issue:1

    Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Agents, Alkylating; Blotting, Western; Brain Neopla

2007
Prognosis factors of survival time in patients with glioblastoma multiforme: a multivariate analysis of 340 patients.
    Acta neurochirurgica, 2007, Volume: 149, Issue:3

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Brain Neoplasms; Chemotherapy, Adjuvant; Combined Modali

2007
Prognosis factors of survival time in patients with glioblastoma multiforme: a multivariate analysis of 340 patients.
    Acta neurochirurgica, 2007, Volume: 149, Issue:3

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Brain Neoplasms; Chemotherapy, Adjuvant; Combined Modali

2007
Prognosis factors of survival time in patients with glioblastoma multiforme: a multivariate analysis of 340 patients.
    Acta neurochirurgica, 2007, Volume: 149, Issue:3

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Brain Neoplasms; Chemotherapy, Adjuvant; Combined Modali

2007
Cross-priming by temozolomide enhances antitumor immunity of dendritic cell vaccination in murine brain tumor model.
    Vaccine, 2007, Apr-30, Volume: 25, Issue:17

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cross-Priming; Dacarbazine; Dendritic C

2007
Cross-priming by temozolomide enhances antitumor immunity of dendritic cell vaccination in murine brain tumor model.
    Vaccine, 2007, Apr-30, Volume: 25, Issue:17

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cross-Priming; Dacarbazine; Dendritic C

2007
Cross-priming by temozolomide enhances antitumor immunity of dendritic cell vaccination in murine brain tumor model.
    Vaccine, 2007, Apr-30, Volume: 25, Issue:17

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cross-Priming; Dacarbazine; Dendritic C

2007
[Cerebral tumours in the adult. A real increase].
    La Revue du praticien, 2006, Oct-31, Volume: 56, Issue:16

    Topics: Adult; Age Factors; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Clinical Trials, Phase

2006
[Cerebral tumours in the adult. A real increase].
    La Revue du praticien, 2006, Oct-31, Volume: 56, Issue:16

    Topics: Adult; Age Factors; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Clinical Trials, Phase

2006
[Cerebral tumours in the adult. A real increase].
    La Revue du praticien, 2006, Oct-31, Volume: 56, Issue:16

    Topics: Adult; Age Factors; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Clinical Trials, Phase

2006
O (4)-benzylfolic acid inactivates O (6)-alkylguanine-DNA alkyltransferase in brain tumor cell lines.
    Cancer chemotherapy and pharmacology, 2007, Volume: 60, Issue:6

    Topics: Antineoplastic Agents, Alkylating; Binding, Competitive; Brain Neoplasms; Carrier Proteins; Cell Lin

2007
O (4)-benzylfolic acid inactivates O (6)-alkylguanine-DNA alkyltransferase in brain tumor cell lines.
    Cancer chemotherapy and pharmacology, 2007, Volume: 60, Issue:6

    Topics: Antineoplastic Agents, Alkylating; Binding, Competitive; Brain Neoplasms; Carrier Proteins; Cell Lin

2007
O (4)-benzylfolic acid inactivates O (6)-alkylguanine-DNA alkyltransferase in brain tumor cell lines.
    Cancer chemotherapy and pharmacology, 2007, Volume: 60, Issue:6

    Topics: Antineoplastic Agents, Alkylating; Binding, Competitive; Brain Neoplasms; Carrier Proteins; Cell Lin

2007
Fatal outcome related to carmustine implants in glioblastoma multiforme.
    Acta neurochirurgica, 2007, Volume: 149, Issue:3

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neoplasms; Carmustine; Chemothera

2007
Fatal outcome related to carmustine implants in glioblastoma multiforme.
    Acta neurochirurgica, 2007, Volume: 149, Issue:3

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neoplasms; Carmustine; Chemothera

2007
Fatal outcome related to carmustine implants in glioblastoma multiforme.
    Acta neurochirurgica, 2007, Volume: 149, Issue:3

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neoplasms; Carmustine; Chemothera

2007
Dynamics of chemosensitivity and chromosomal instability in recurrent glioblastoma.
    British journal of cancer, 2007, Mar-26, Volume: 96, Issue:6

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Chromosomal Instability; Dacar

2007
Dynamics of chemosensitivity and chromosomal instability in recurrent glioblastoma.
    British journal of cancer, 2007, Mar-26, Volume: 96, Issue:6

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Chromosomal Instability; Dacar

2007
Dynamics of chemosensitivity and chromosomal instability in recurrent glioblastoma.
    British journal of cancer, 2007, Mar-26, Volume: 96, Issue:6

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Chromosomal Instability; Dacar

2007
The inhibition of proliferation and migration of glioma spheroids exposed to temozolomide is less than additive if combined with irradiation.
    Oncology reports, 2007, Volume: 17, Issue:4

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Movement; Cell Proliferation; Combined Moda

2007
The inhibition of proliferation and migration of glioma spheroids exposed to temozolomide is less than additive if combined with irradiation.
    Oncology reports, 2007, Volume: 17, Issue:4

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Movement; Cell Proliferation; Combined Moda

2007
The inhibition of proliferation and migration of glioma spheroids exposed to temozolomide is less than additive if combined with irradiation.
    Oncology reports, 2007, Volume: 17, Issue:4

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Movement; Cell Proliferation; Combined Moda

2007
Hepatitis B reactivation during glioblastoma treatment with temozolomide: a cautionary note.
    Neurology, 2007, Mar-20, Volume: 68, Issue:12

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; DNA, Viral; Glioblastoma; Hepatitis

2007
Hepatitis B reactivation during glioblastoma treatment with temozolomide: a cautionary note.
    Neurology, 2007, Mar-20, Volume: 68, Issue:12

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; DNA, Viral; Glioblastoma; Hepatitis

2007
Hepatitis B reactivation during glioblastoma treatment with temozolomide: a cautionary note.
    Neurology, 2007, Mar-20, Volume: 68, Issue:12

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; DNA, Viral; Glioblastoma; Hepatitis

2007
Oncolytic herpes simplex virus mutants exhibit enhanced replication in glioma cells evading temozolomide chemotherapy through deoxyribonucleic acid repair.
    Clinical neurosurgery, 2006, Volume: 53

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Culture Techniques; Cell Line, Tum

2006
Oncolytic herpes simplex virus mutants exhibit enhanced replication in glioma cells evading temozolomide chemotherapy through deoxyribonucleic acid repair.
    Clinical neurosurgery, 2006, Volume: 53

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Culture Techniques; Cell Line, Tum

2006
Oncolytic herpes simplex virus mutants exhibit enhanced replication in glioma cells evading temozolomide chemotherapy through deoxyribonucleic acid repair.
    Clinical neurosurgery, 2006, Volume: 53

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Culture Techniques; Cell Line, Tum

2006
Loss of the mismatch repair protein MSH6 in human glioblastomas is associated with tumor progression during temozolomide treatment.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2007, Apr-01, Volume: 13, Issue:7

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Proliferation; Dacarbazine; Di

2007
Loss of the mismatch repair protein MSH6 in human glioblastomas is associated with tumor progression during temozolomide treatment.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2007, Apr-01, Volume: 13, Issue:7

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Proliferation; Dacarbazine; Di

2007
Loss of the mismatch repair protein MSH6 in human glioblastomas is associated with tumor progression during temozolomide treatment.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2007, Apr-01, Volume: 13, Issue:7

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Proliferation; Dacarbazine; Di

2007
Loss of the mismatch repair protein MSH6 in human glioblastomas is associated with tumor progression during temozolomide treatment.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2007, Apr-01, Volume: 13, Issue:7

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Proliferation; Dacarbazine; Di

2007
Loss of the mismatch repair protein MSH6 in human glioblastomas is associated with tumor progression during temozolomide treatment.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2007, Apr-01, Volume: 13, Issue:7

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Proliferation; Dacarbazine; Di

2007
Loss of the mismatch repair protein MSH6 in human glioblastomas is associated with tumor progression during temozolomide treatment.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2007, Apr-01, Volume: 13, Issue:7

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Proliferation; Dacarbazine; Di

2007
Loss of the mismatch repair protein MSH6 in human glioblastomas is associated with tumor progression during temozolomide treatment.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2007, Apr-01, Volume: 13, Issue:7

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Proliferation; Dacarbazine; Di

2007
Loss of the mismatch repair protein MSH6 in human glioblastomas is associated with tumor progression during temozolomide treatment.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2007, Apr-01, Volume: 13, Issue:7

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Proliferation; Dacarbazine; Di

2007
Loss of the mismatch repair protein MSH6 in human glioblastomas is associated with tumor progression during temozolomide treatment.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2007, Apr-01, Volume: 13, Issue:7

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Proliferation; Dacarbazine; Di

2007
Loss of the mismatch repair protein MSH6 in human glioblastomas is associated with tumor progression during temozolomide treatment.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2007, Apr-01, Volume: 13, Issue:7

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Proliferation; Dacarbazine; Di

2007
Loss of the mismatch repair protein MSH6 in human glioblastomas is associated with tumor progression during temozolomide treatment.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2007, Apr-01, Volume: 13, Issue:7

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Proliferation; Dacarbazine; Di

2007
Loss of the mismatch repair protein MSH6 in human glioblastomas is associated with tumor progression during temozolomide treatment.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2007, Apr-01, Volume: 13, Issue:7

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Proliferation; Dacarbazine; Di

2007
Taming a mutinous mutant: an errant receptor becomes a prime cancer target.
    Journal of the National Cancer Institute, 2007, Apr-04, Volume: 99, Issue:7

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cancer Vaccines; Combined Modality Therapy; Daca

2007
Taming a mutinous mutant: an errant receptor becomes a prime cancer target.
    Journal of the National Cancer Institute, 2007, Apr-04, Volume: 99, Issue:7

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cancer Vaccines; Combined Modality Therapy; Daca

2007
Taming a mutinous mutant: an errant receptor becomes a prime cancer target.
    Journal of the National Cancer Institute, 2007, Apr-04, Volume: 99, Issue:7

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cancer Vaccines; Combined Modality Therapy; Daca

2007
Temozolomide as prophylaxis for brain metastasis in non-small cell lung cancer.
    Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer, 2006, Volume: 1, Issue:7

    Topics: Antineoplastic Agents, Alkylating; Antineoplastic Agents, Phytogenic; Brain Neoplasms; Camptothecin;

2006
Temozolomide as prophylaxis for brain metastasis in non-small cell lung cancer.
    Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer, 2006, Volume: 1, Issue:7

    Topics: Antineoplastic Agents, Alkylating; Antineoplastic Agents, Phytogenic; Brain Neoplasms; Camptothecin;

2006
Temozolomide as prophylaxis for brain metastasis in non-small cell lung cancer.
    Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer, 2006, Volume: 1, Issue:7

    Topics: Antineoplastic Agents, Alkylating; Antineoplastic Agents, Phytogenic; Brain Neoplasms; Camptothecin;

2006
Fatal reactivation of hepatitis B with temozolomide.
    The New England journal of medicine, 2007, Apr-12, Volume: 356, Issue:15

    Topics: Aged; Anticonvulsants; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Fatal Outcom

2007
Fatal reactivation of hepatitis B with temozolomide.
    The New England journal of medicine, 2007, Apr-12, Volume: 356, Issue:15

    Topics: Aged; Anticonvulsants; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Fatal Outcom

2007
Fatal reactivation of hepatitis B with temozolomide.
    The New England journal of medicine, 2007, Apr-12, Volume: 356, Issue:15

    Topics: Aged; Anticonvulsants; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Fatal Outcom

2007
A small proportion of glioblastoma patients are probably eligible for concomitant/adjuvant temozolomide.
    Clinical oncology (Royal College of Radiologists (Great Britain)), 2007, Volume: 19, Issue:4

    Topics: Adjuvants, Immunologic; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therap

2007
A small proportion of glioblastoma patients are probably eligible for concomitant/adjuvant temozolomide.
    Clinical oncology (Royal College of Radiologists (Great Britain)), 2007, Volume: 19, Issue:4

    Topics: Adjuvants, Immunologic; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therap

2007
A small proportion of glioblastoma patients are probably eligible for concomitant/adjuvant temozolomide.
    Clinical oncology (Royal College of Radiologists (Great Britain)), 2007, Volume: 19, Issue:4

    Topics: Adjuvants, Immunologic; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therap

2007
Multiple gangliogliomas of the optic pathway.
    British journal of neurosurgery, 2006, Volume: 20, Issue:6

    Topics: Adolescent; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Ganglioglioma; Humans;

2006
Multiple gangliogliomas of the optic pathway.
    British journal of neurosurgery, 2006, Volume: 20, Issue:6

    Topics: Adolescent; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Ganglioglioma; Humans;

2006
Multiple gangliogliomas of the optic pathway.
    British journal of neurosurgery, 2006, Volume: 20, Issue:6

    Topics: Adolescent; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Ganglioglioma; Humans;

2006
Methylguanine methyltransferase testing in glioblastoma: when and how?
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2007, Apr-20, Volume: 25, Issue:12

    Topics: Biomarkers, Tumor; Brain Neoplasms; Dacarbazine; Female; Glioblastoma; Humans; Male; Neoplasm Stagin

2007
Methylguanine methyltransferase testing in glioblastoma: when and how?
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2007, Apr-20, Volume: 25, Issue:12

    Topics: Biomarkers, Tumor; Brain Neoplasms; Dacarbazine; Female; Glioblastoma; Humans; Male; Neoplasm Stagin

2007
Methylguanine methyltransferase testing in glioblastoma: when and how?
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2007, Apr-20, Volume: 25, Issue:12

    Topics: Biomarkers, Tumor; Brain Neoplasms; Dacarbazine; Female; Glioblastoma; Humans; Male; Neoplasm Stagin

2007
Dynamic history of low-grade gliomas before and after temozolomide treatment.
    Annals of neurology, 2007, Volume: 61, Issue:5

    Topics: Adult; Aged; Algorithms; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chromosomes; Dacarbazin

2007
Dynamic history of low-grade gliomas before and after temozolomide treatment.
    Annals of neurology, 2007, Volume: 61, Issue:5

    Topics: Adult; Aged; Algorithms; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chromosomes; Dacarbazin

2007
Dynamic history of low-grade gliomas before and after temozolomide treatment.
    Annals of neurology, 2007, Volume: 61, Issue:5

    Topics: Adult; Aged; Algorithms; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chromosomes; Dacarbazin

2007
Phosphatase and tensin homologue deficiency in glioblastoma confers resistance to radiation and temozolomide that is reversed by the protease inhibitor nelfinavir.
    Cancer research, 2007, May-01, Volume: 67, Issue:9

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Dacarbazine; Drug Int

2007
Phosphatase and tensin homologue deficiency in glioblastoma confers resistance to radiation and temozolomide that is reversed by the protease inhibitor nelfinavir.
    Cancer research, 2007, May-01, Volume: 67, Issue:9

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Dacarbazine; Drug Int

2007
Phosphatase and tensin homologue deficiency in glioblastoma confers resistance to radiation and temozolomide that is reversed by the protease inhibitor nelfinavir.
    Cancer research, 2007, May-01, Volume: 67, Issue:9

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Dacarbazine; Drug Int

2007
Adjuvant therapy in glioblastomas: false steps and real advances.
    Expert review of anticancer therapy, 2007, Volume: 7, Issue:5

    Topics: Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carmustine; Chemotherapy, Adjuvant;

2007
Adjuvant therapy in glioblastomas: false steps and real advances.
    Expert review of anticancer therapy, 2007, Volume: 7, Issue:5

    Topics: Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carmustine; Chemotherapy, Adjuvant;

2007
Adjuvant therapy in glioblastomas: false steps and real advances.
    Expert review of anticancer therapy, 2007, Volume: 7, Issue:5

    Topics: Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carmustine; Chemotherapy, Adjuvant;

2007
Magnetic resonance imaging determination of tumor grade and early response to temozolomide in a genetically engineered mouse model of glioma.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2007, May-15, Volume: 13, Issue:10

    Topics: Animals; Brain Neoplasms; Dacarbazine; Disease Models, Animal; Genetic Engineering; Glioma; Magnetic

2007
Magnetic resonance imaging determination of tumor grade and early response to temozolomide in a genetically engineered mouse model of glioma.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2007, May-15, Volume: 13, Issue:10

    Topics: Animals; Brain Neoplasms; Dacarbazine; Disease Models, Animal; Genetic Engineering; Glioma; Magnetic

2007
Magnetic resonance imaging determination of tumor grade and early response to temozolomide in a genetically engineered mouse model of glioma.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2007, May-15, Volume: 13, Issue:10

    Topics: Animals; Brain Neoplasms; Dacarbazine; Disease Models, Animal; Genetic Engineering; Glioma; Magnetic

2007
Mathematical modeling of brain tumors: effects of radiotherapy and chemotherapy.
    Physics in medicine and biology, 2007, Jun-07, Volume: 52, Issue:11

    Topics: Antineoplastic Agents; Brain; Brain Neoplasms; Chemotherapy, Adjuvant; Clinical Trials as Topic; Com

2007
Mathematical modeling of brain tumors: effects of radiotherapy and chemotherapy.
    Physics in medicine and biology, 2007, Jun-07, Volume: 52, Issue:11

    Topics: Antineoplastic Agents; Brain; Brain Neoplasms; Chemotherapy, Adjuvant; Clinical Trials as Topic; Com

2007
Mathematical modeling of brain tumors: effects of radiotherapy and chemotherapy.
    Physics in medicine and biology, 2007, Jun-07, Volume: 52, Issue:11

    Topics: Antineoplastic Agents; Brain; Brain Neoplasms; Chemotherapy, Adjuvant; Clinical Trials as Topic; Com

2007
Unexpected case of aplastic anemia in a patient with glioblastoma multiforme treated with Temozolomide.
    Journal of neuro-oncology, 2007, Volume: 85, Issue:1

    Topics: Adult; Anemia, Aplastic; Antineoplastic Agents, Alkylating; Blood Cell Count; Bone Marrow; Brain Neo

2007
Unexpected case of aplastic anemia in a patient with glioblastoma multiforme treated with Temozolomide.
    Journal of neuro-oncology, 2007, Volume: 85, Issue:1

    Topics: Adult; Anemia, Aplastic; Antineoplastic Agents, Alkylating; Blood Cell Count; Bone Marrow; Brain Neo

2007
Unexpected case of aplastic anemia in a patient with glioblastoma multiforme treated with Temozolomide.
    Journal of neuro-oncology, 2007, Volume: 85, Issue:1

    Topics: Adult; Anemia, Aplastic; Antineoplastic Agents, Alkylating; Blood Cell Count; Bone Marrow; Brain Neo

2007
Temozolomide for low-grade gliomas: predictive impact of 1p/19q loss on response and outcome.
    Neurology, 2007, May-22, Volume: 68, Issue:21

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chromosome Deletion; Chromosomes, H

2007
Temozolomide for low-grade gliomas: predictive impact of 1p/19q loss on response and outcome.
    Neurology, 2007, May-22, Volume: 68, Issue:21

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chromosome Deletion; Chromosomes, H

2007
Temozolomide for low-grade gliomas: predictive impact of 1p/19q loss on response and outcome.
    Neurology, 2007, May-22, Volume: 68, Issue:21

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chromosome Deletion; Chromosomes, H

2007
Preferential migration of regulatory T cells mediated by glioma-secreted chemokines can be blocked with chemotherapy.
    Cancer immunology, immunotherapy : CII, 2008, Volume: 57, Issue:1

    Topics: Antineoplastic Agents; Brain Neoplasms; Carmustine; Cell Line, Tumor; Chemokine CCL2; Chemokine CCL2

2008
Preferential migration of regulatory T cells mediated by glioma-secreted chemokines can be blocked with chemotherapy.
    Cancer immunology, immunotherapy : CII, 2008, Volume: 57, Issue:1

    Topics: Antineoplastic Agents; Brain Neoplasms; Carmustine; Cell Line, Tumor; Chemokine CCL2; Chemokine CCL2

2008
Preferential migration of regulatory T cells mediated by glioma-secreted chemokines can be blocked with chemotherapy.
    Cancer immunology, immunotherapy : CII, 2008, Volume: 57, Issue:1

    Topics: Antineoplastic Agents; Brain Neoplasms; Carmustine; Cell Line, Tumor; Chemokine CCL2; Chemokine CCL2

2008
Complete response to temozolomide treatment in an elderly patient with recurrent primary central nervous system lymphoma--case report.
    Neurologia medico-chirurgica, 2007, Volume: 47, Issue:5

    Topics: Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Female; Humans;

2007
Complete response to temozolomide treatment in an elderly patient with recurrent primary central nervous system lymphoma--case report.
    Neurologia medico-chirurgica, 2007, Volume: 47, Issue:5

    Topics: Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Female; Humans;

2007
Complete response to temozolomide treatment in an elderly patient with recurrent primary central nervous system lymphoma--case report.
    Neurologia medico-chirurgica, 2007, Volume: 47, Issue:5

    Topics: Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Female; Humans;

2007
Improved median survival for glioblastoma multiforme following introduction of adjuvant temozolomide chemotherapy.
    Annals of the Academy of Medicine, Singapore, 2007, Volume: 36, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant; Dacarbazine; Female; Gli

2007
Improved median survival for glioblastoma multiforme following introduction of adjuvant temozolomide chemotherapy.
    Annals of the Academy of Medicine, Singapore, 2007, Volume: 36, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant; Dacarbazine; Female; Gli

2007
Improved median survival for glioblastoma multiforme following introduction of adjuvant temozolomide chemotherapy.
    Annals of the Academy of Medicine, Singapore, 2007, Volume: 36, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant; Dacarbazine; Female; Gli

2007
Salvage chemotherapy in progressive high-grade astrocytoma.
    Annals of the Academy of Medicine, Singapore, 2007, Volume: 36, Issue:5

    Topics: Adult; Astrocytoma; Brain Neoplasms; Dacarbazine; Female; Glioblastoma; Humans; Male; Middle Aged; R

2007
Salvage chemotherapy in progressive high-grade astrocytoma.
    Annals of the Academy of Medicine, Singapore, 2007, Volume: 36, Issue:5

    Topics: Adult; Astrocytoma; Brain Neoplasms; Dacarbazine; Female; Glioblastoma; Humans; Male; Middle Aged; R

2007
Salvage chemotherapy in progressive high-grade astrocytoma.
    Annals of the Academy of Medicine, Singapore, 2007, Volume: 36, Issue:5

    Topics: Adult; Astrocytoma; Brain Neoplasms; Dacarbazine; Female; Glioblastoma; Humans; Male; Middle Aged; R

2007
Inhibition of Aurora-B function increases formation of multinucleated cells in p53 gene deficient cells and enhances anti-tumor effect of temozolomide in human glioma cells.
    Journal of neuro-oncology, 2007, Volume: 83, Issue:3

    Topics: Antineoplastic Agents, Alkylating; Aurora Kinase B; Aurora Kinases; Blotting, Western; Brain Neoplas

2007
Inhibition of Aurora-B function increases formation of multinucleated cells in p53 gene deficient cells and enhances anti-tumor effect of temozolomide in human glioma cells.
    Journal of neuro-oncology, 2007, Volume: 83, Issue:3

    Topics: Antineoplastic Agents, Alkylating; Aurora Kinase B; Aurora Kinases; Blotting, Western; Brain Neoplas

2007
Inhibition of Aurora-B function increases formation of multinucleated cells in p53 gene deficient cells and enhances anti-tumor effect of temozolomide in human glioma cells.
    Journal of neuro-oncology, 2007, Volume: 83, Issue:3

    Topics: Antineoplastic Agents, Alkylating; Aurora Kinase B; Aurora Kinases; Blotting, Western; Brain Neoplas

2007
Temozolomide in pediatric low-grade glioma.
    Pediatric blood & cancer, 2007, Volume: 49, Issue:6

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Astrocytoma; Brain Neoplasms; Carboplati

2007
Temozolomide in pediatric low-grade glioma.
    Pediatric blood & cancer, 2007, Volume: 49, Issue:6

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Astrocytoma; Brain Neoplasms; Carboplati

2007
Temozolomide in pediatric low-grade glioma.
    Pediatric blood & cancer, 2007, Volume: 49, Issue:6

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Astrocytoma; Brain Neoplasms; Carboplati

2007
Radiochemotherapy for brain metastasis: how to define a role for temozolomide.
    Onkologie, 2007, Volume: 30, Issue:7

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Breast Neoplasms; Carcinoma, Non-Small-Cell Lung

2007
Radiochemotherapy for brain metastasis: how to define a role for temozolomide.
    Onkologie, 2007, Volume: 30, Issue:7

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Breast Neoplasms; Carcinoma, Non-Small-Cell Lung

2007
Radiochemotherapy for brain metastasis: how to define a role for temozolomide.
    Onkologie, 2007, Volume: 30, Issue:7

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Breast Neoplasms; Carcinoma, Non-Small-Cell Lung

2007
Defining the standard of care for high-grade glioma--a NICE deal for UK patients?
    Clinical oncology (Royal College of Radiologists (Great Britain)), 2007, Volume: 19, Issue:7

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant; Dacarbazine; Delivery of

2007
Defining the standard of care for high-grade glioma--a NICE deal for UK patients?
    Clinical oncology (Royal College of Radiologists (Great Britain)), 2007, Volume: 19, Issue:7

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant; Dacarbazine; Delivery of

2007
Defining the standard of care for high-grade glioma--a NICE deal for UK patients?
    Clinical oncology (Royal College of Radiologists (Great Britain)), 2007, Volume: 19, Issue:7

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant; Dacarbazine; Delivery of

2007
Biochemotherapy of metastatic melanoma in patients with or without recently diagnosed brain metastases.
    Cancer, 2007, Sep-15, Volume: 110, Issue:6

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Dacarbazine; Female; H

2007
Biochemotherapy of metastatic melanoma in patients with or without recently diagnosed brain metastases.
    Cancer, 2007, Sep-15, Volume: 110, Issue:6

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Dacarbazine; Female; H

2007
Biochemotherapy of metastatic melanoma in patients with or without recently diagnosed brain metastases.
    Cancer, 2007, Sep-15, Volume: 110, Issue:6

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Dacarbazine; Female; H

2007
Prophylactic radiotherapy for glioblastoma in the elderly.
    The New England journal of medicine, 2007, Jul-12, Volume: 357, Issue:2

    Topics: Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Gl

2007
Prophylactic radiotherapy for glioblastoma in the elderly.
    The New England journal of medicine, 2007, Jul-12, Volume: 357, Issue:2

    Topics: Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Gl

2007
Prophylactic radiotherapy for glioblastoma in the elderly.
    The New England journal of medicine, 2007, Jul-12, Volume: 357, Issue:2

    Topics: Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Gl

2007
Predicting human tumor drug concentrations from a preclinical pharmacokinetic model of temozolomide brain disposition.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2007, Jul-15, Volume: 13, Issue:14

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain; Brain Neoplasms; Dacarbazine; Humans; Models, Ani

2007
Predicting human tumor drug concentrations from a preclinical pharmacokinetic model of temozolomide brain disposition.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2007, Jul-15, Volume: 13, Issue:14

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain; Brain Neoplasms; Dacarbazine; Humans; Models, Ani

2007
Predicting human tumor drug concentrations from a preclinical pharmacokinetic model of temozolomide brain disposition.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2007, Jul-15, Volume: 13, Issue:14

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain; Brain Neoplasms; Dacarbazine; Humans; Models, Ani

2007
The fallacy of single-agent chemotherapy for cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2007, Aug-10, Volume: 25, Issue:23

    Topics: Antineoplastic Agents, Alkylating; Biomarkers, Tumor; Brain Neoplasms; Dacarbazine; Glioblastoma; Hu

2007
The fallacy of single-agent chemotherapy for cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2007, Aug-10, Volume: 25, Issue:23

    Topics: Antineoplastic Agents, Alkylating; Biomarkers, Tumor; Brain Neoplasms; Dacarbazine; Glioblastoma; Hu

2007
The fallacy of single-agent chemotherapy for cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2007, Aug-10, Volume: 25, Issue:23

    Topics: Antineoplastic Agents, Alkylating; Biomarkers, Tumor; Brain Neoplasms; Dacarbazine; Glioblastoma; Hu

2007
MS-MLPA: an attractive alternative laboratory assay for robust, reliable, and semiquantitative detection of MGMT promoter hypermethylation in gliomas.
    Laboratory investigation; a journal of technical methods and pathology, 2007, Volume: 87, Issue:10

    Topics: Antineoplastic Agents, Alkylating; Base Sequence; Biopsy; Brain Neoplasms; Cell Line, Tumor; Dacarba

2007
MS-MLPA: an attractive alternative laboratory assay for robust, reliable, and semiquantitative detection of MGMT promoter hypermethylation in gliomas.
    Laboratory investigation; a journal of technical methods and pathology, 2007, Volume: 87, Issue:10

    Topics: Antineoplastic Agents, Alkylating; Base Sequence; Biopsy; Brain Neoplasms; Cell Line, Tumor; Dacarba

2007
MS-MLPA: an attractive alternative laboratory assay for robust, reliable, and semiquantitative detection of MGMT promoter hypermethylation in gliomas.
    Laboratory investigation; a journal of technical methods and pathology, 2007, Volume: 87, Issue:10

    Topics: Antineoplastic Agents, Alkylating; Base Sequence; Biopsy; Brain Neoplasms; Cell Line, Tumor; Dacarba

2007
Efficacy of temozolomide is correlated with 1p loss and methylation of the deoxyribonucleic acid repair gene MGMT in malignant gliomas.
    Neurologia medico-chirurgica, 2007, Volume: 47, Issue:8

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Biomarkers, Tumor; Brain Neoplasms; Chro

2007
Efficacy of temozolomide is correlated with 1p loss and methylation of the deoxyribonucleic acid repair gene MGMT in malignant gliomas.
    Neurologia medico-chirurgica, 2007, Volume: 47, Issue:8

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Biomarkers, Tumor; Brain Neoplasms; Chro

2007
Efficacy of temozolomide is correlated with 1p loss and methylation of the deoxyribonucleic acid repair gene MGMT in malignant gliomas.
    Neurologia medico-chirurgica, 2007, Volume: 47, Issue:8

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Biomarkers, Tumor; Brain Neoplasms; Chro

2007
Predictors of distant brain recurrence for patients with newly diagnosed brain metastases treated with stereotactic radiosurgery alone.
    International journal of radiation oncology, biology, physics, 2008, Jan-01, Volume: 70, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Breast Neoplasms

2008
Predictors of distant brain recurrence for patients with newly diagnosed brain metastases treated with stereotactic radiosurgery alone.
    International journal of radiation oncology, biology, physics, 2008, Jan-01, Volume: 70, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Breast Neoplasms

2008
Predictors of distant brain recurrence for patients with newly diagnosed brain metastases treated with stereotactic radiosurgery alone.
    International journal of radiation oncology, biology, physics, 2008, Jan-01, Volume: 70, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Breast Neoplasms

2008
What approach will lead to cure of glioblastoma multiforme? In regard to Barani et al. (Int J Radiat Oncol Biol Phys 2007;68:324-333) and Jones and Sanghera (Int J Radiat Oncol Biol Phys 2007;68:441-448).
    International journal of radiation oncology, biology, physics, 2007, Oct-01, Volume: 69, Issue:2

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Central Nervous System Neoplasms; Dacarbazine; G

2007
What approach will lead to cure of glioblastoma multiforme? In regard to Barani et al. (Int J Radiat Oncol Biol Phys 2007;68:324-333) and Jones and Sanghera (Int J Radiat Oncol Biol Phys 2007;68:441-448).
    International journal of radiation oncology, biology, physics, 2007, Oct-01, Volume: 69, Issue:2

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Central Nervous System Neoplasms; Dacarbazine; G

2007
What approach will lead to cure of glioblastoma multiforme? In regard to Barani et al. (Int J Radiat Oncol Biol Phys 2007;68:324-333) and Jones and Sanghera (Int J Radiat Oncol Biol Phys 2007;68:441-448).
    International journal of radiation oncology, biology, physics, 2007, Oct-01, Volume: 69, Issue:2

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Central Nervous System Neoplasms; Dacarbazine; G

2007
Bioluminescence monitoring of intracranial glioblastoma xenograft: response to primary and salvage temozolomide therapy.
    Journal of neurosurgery, 2007, Volume: 107, Issue:3

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Disease Models, Animal; Gl

2007
Bioluminescence monitoring of intracranial glioblastoma xenograft: response to primary and salvage temozolomide therapy.
    Journal of neurosurgery, 2007, Volume: 107, Issue:3

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Disease Models, Animal; Gl

2007
Bioluminescence monitoring of intracranial glioblastoma xenograft: response to primary and salvage temozolomide therapy.
    Journal of neurosurgery, 2007, Volume: 107, Issue:3

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Disease Models, Animal; Gl

2007
Pharmacokinetic study of temozolomide on a daily-for-5-days schedule in Japanese patients with relapsed malignant gliomas: first study in Asians.
    International journal of clinical oncology, 2007, Volume: 12, Issue:5

    Topics: Administration, Oral; Adult; Antineoplastic Agents, Alkylating; Area Under Curve; Asian People; Brai

2007
Pharmacokinetic study of temozolomide on a daily-for-5-days schedule in Japanese patients with relapsed malignant gliomas: first study in Asians.
    International journal of clinical oncology, 2007, Volume: 12, Issue:5

    Topics: Administration, Oral; Adult; Antineoplastic Agents, Alkylating; Area Under Curve; Asian People; Brai

2007
Pharmacokinetic study of temozolomide on a daily-for-5-days schedule in Japanese patients with relapsed malignant gliomas: first study in Asians.
    International journal of clinical oncology, 2007, Volume: 12, Issue:5

    Topics: Administration, Oral; Adult; Antineoplastic Agents, Alkylating; Area Under Curve; Asian People; Brai

2007
The unfolded protein response regulator GRP78/BiP as a novel target for increasing chemosensitivity in malignant gliomas.
    Cancer research, 2007, Oct-15, Volume: 67, Issue:20

    Topics: Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Camptothecin; Caspase 7; Catechin;

2007
The unfolded protein response regulator GRP78/BiP as a novel target for increasing chemosensitivity in malignant gliomas.
    Cancer research, 2007, Oct-15, Volume: 67, Issue:20

    Topics: Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Camptothecin; Caspase 7; Catechin;

2007
The unfolded protein response regulator GRP78/BiP as a novel target for increasing chemosensitivity in malignant gliomas.
    Cancer research, 2007, Oct-15, Volume: 67, Issue:20

    Topics: Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Camptothecin; Caspase 7; Catechin;

2007
Adenovirally delivered tumor necrosis factor-alpha improves the antiglioma efficacy of concomitant radiation and temozolomide therapy.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2007, Oct-15, Volume: 13, Issue:20

    Topics: Adenoviridae; Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Combine

2007
Adenovirally delivered tumor necrosis factor-alpha improves the antiglioma efficacy of concomitant radiation and temozolomide therapy.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2007, Oct-15, Volume: 13, Issue:20

    Topics: Adenoviridae; Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Combine

2007
Adenovirally delivered tumor necrosis factor-alpha improves the antiglioma efficacy of concomitant radiation and temozolomide therapy.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2007, Oct-15, Volume: 13, Issue:20

    Topics: Adenoviridae; Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Combine

2007
Defining the standard of care for high-grade glioma--a NICE deal for patients.
    Clinical oncology (Royal College of Radiologists (Great Britain)), 2008, Volume: 20, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Glioblastoma; Humans; Temozolomide

2008
Defining the standard of care for high-grade glioma--a NICE deal for patients.
    Clinical oncology (Royal College of Radiologists (Great Britain)), 2008, Volume: 20, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Glioblastoma; Humans; Temozolomide

2008
Defining the standard of care for high-grade glioma--a NICE deal for patients.
    Clinical oncology (Royal College of Radiologists (Great Britain)), 2008, Volume: 20, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Glioblastoma; Humans; Temozolomide

2008
Differential radiosensitizing potential of temozolomide in MGMT promoter methylated glioblastoma multiforme cell lines.
    International journal of radiation oncology, biology, physics, 2007, Nov-15, Volume: 69, Issue:4

    Topics: Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Cell Survival; Combined Modality Therapy; Dac

2007
Differential radiosensitizing potential of temozolomide in MGMT promoter methylated glioblastoma multiforme cell lines.
    International journal of radiation oncology, biology, physics, 2007, Nov-15, Volume: 69, Issue:4

    Topics: Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Cell Survival; Combined Modality Therapy; Dac

2007
Differential radiosensitizing potential of temozolomide in MGMT promoter methylated glioblastoma multiforme cell lines.
    International journal of radiation oncology, biology, physics, 2007, Nov-15, Volume: 69, Issue:4

    Topics: Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Cell Survival; Combined Modality Therapy; Dac

2007
Postoperative treatment of primary glioblastoma multiforme with radiation and concomitant temozolomide in elderly patients.
    International journal of radiation oncology, biology, physics, 2008, Mar-15, Volume: 70, Issue:4

    Topics: Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Fe

2008
Postoperative treatment of primary glioblastoma multiforme with radiation and concomitant temozolomide in elderly patients.
    International journal of radiation oncology, biology, physics, 2008, Mar-15, Volume: 70, Issue:4

    Topics: Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Fe

2008
Postoperative treatment of primary glioblastoma multiforme with radiation and concomitant temozolomide in elderly patients.
    International journal of radiation oncology, biology, physics, 2008, Mar-15, Volume: 70, Issue:4

    Topics: Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Fe

2008
Variation of O(6)-methylguanine-DNA methyltransferase (MGMT) promoter methylation in serial samples in glioblastoma.
    Journal of neuro-oncology, 2008, Volume: 87, Issue:1

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; DNA Methylation; DNA M

2008
Variation of O(6)-methylguanine-DNA methyltransferase (MGMT) promoter methylation in serial samples in glioblastoma.
    Journal of neuro-oncology, 2008, Volume: 87, Issue:1

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; DNA Methylation; DNA M

2008
Variation of O(6)-methylguanine-DNA methyltransferase (MGMT) promoter methylation in serial samples in glioblastoma.
    Journal of neuro-oncology, 2008, Volume: 87, Issue:1

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; DNA Methylation; DNA M

2008
Postoperative radiotherapy of glioblastoma multiforme: analysis and critical assessment of different treatment strategies and predictive factors.
    Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 2007, Volume: 183, Issue:12

    Topics: Adult; Aged, 80 and over; Animals; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Biopsy;

2007
Postoperative radiotherapy of glioblastoma multiforme: analysis and critical assessment of different treatment strategies and predictive factors.
    Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 2007, Volume: 183, Issue:12

    Topics: Adult; Aged, 80 and over; Animals; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Biopsy;

2007
Postoperative radiotherapy of glioblastoma multiforme: analysis and critical assessment of different treatment strategies and predictive factors.
    Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 2007, Volume: 183, Issue:12

    Topics: Adult; Aged, 80 and over; Animals; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Biopsy;

2007
Diffusion tensor imaging and chemical shift imaging assessment of heterogeneity in low grade glioma under temozolomide chemotherapy.
    Cancer investigation, 2007, Volume: 25, Issue:8

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Choline; Dacarbazine; Diffusion Magnetic Resonan

2007
Diffusion tensor imaging and chemical shift imaging assessment of heterogeneity in low grade glioma under temozolomide chemotherapy.
    Cancer investigation, 2007, Volume: 25, Issue:8

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Choline; Dacarbazine; Diffusion Magnetic Resonan

2007
Diffusion tensor imaging and chemical shift imaging assessment of heterogeneity in low grade glioma under temozolomide chemotherapy.
    Cancer investigation, 2007, Volume: 25, Issue:8

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Choline; Dacarbazine; Diffusion Magnetic Resonan

2007
Acquired hypopigmentation (leukoderma) as a presenting feature of metastatic amelanotic melanoma with brain involvement.
    Archives of neurology, 2007, Volume: 64, Issue:12

    Topics: Anti-Inflammatory Agents; Antineoplastic Agents, Alkylating; Brain; Brain Neoplasms; Dacarbazine; De

2007
Acquired hypopigmentation (leukoderma) as a presenting feature of metastatic amelanotic melanoma with brain involvement.
    Archives of neurology, 2007, Volume: 64, Issue:12

    Topics: Anti-Inflammatory Agents; Antineoplastic Agents, Alkylating; Brain; Brain Neoplasms; Dacarbazine; De

2007
Acquired hypopigmentation (leukoderma) as a presenting feature of metastatic amelanotic melanoma with brain involvement.
    Archives of neurology, 2007, Volume: 64, Issue:12

    Topics: Anti-Inflammatory Agents; Antineoplastic Agents, Alkylating; Brain; Brain Neoplasms; Dacarbazine; De

2007
Encouraging experience of concomitant Temozolomide with radiotherapy followed by adjuvant Temozolomide in newly diagnosed glioblastoma multiforme: single institution experience.
    British journal of neurosurgery, 2007, Volume: 21, Issue:6

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant;

2007
Encouraging experience of concomitant Temozolomide with radiotherapy followed by adjuvant Temozolomide in newly diagnosed glioblastoma multiforme: single institution experience.
    British journal of neurosurgery, 2007, Volume: 21, Issue:6

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant;

2007
Encouraging experience of concomitant Temozolomide with radiotherapy followed by adjuvant Temozolomide in newly diagnosed glioblastoma multiforme: single institution experience.
    British journal of neurosurgery, 2007, Volume: 21, Issue:6

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant;

2007
Immunological responses in a patient with glioblastoma multiforme treated with sequential courses of temozolomide and immunotherapy: case study.
    Neuro-oncology, 2008, Volume: 10, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cancer Vaccines; Combined Modality Therapy; Daca

2008
Immunological responses in a patient with glioblastoma multiforme treated with sequential courses of temozolomide and immunotherapy: case study.
    Neuro-oncology, 2008, Volume: 10, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cancer Vaccines; Combined Modality Therapy; Daca

2008
Immunological responses in a patient with glioblastoma multiforme treated with sequential courses of temozolomide and immunotherapy: case study.
    Neuro-oncology, 2008, Volume: 10, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cancer Vaccines; Combined Modality Therapy; Daca

2008
Antiangiogenic compounds interfere with chemotherapy of brain tumors due to vessel normalization.
    Molecular cancer therapeutics, 2008, Volume: 7, Issue:1

    Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Blood-B

2008
Antiangiogenic compounds interfere with chemotherapy of brain tumors due to vessel normalization.
    Molecular cancer therapeutics, 2008, Volume: 7, Issue:1

    Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Blood-B

2008
Antiangiogenic compounds interfere with chemotherapy of brain tumors due to vessel normalization.
    Molecular cancer therapeutics, 2008, Volume: 7, Issue:1

    Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Blood-B

2008
Effects of the VEGFR inhibitor ZD6474 in combination with radiotherapy and temozolomide in an orthotopic glioma model.
    Journal of neuro-oncology, 2008, Volume: 88, Issue:1

    Topics: Animals; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Brain; B

2008
Effects of the VEGFR inhibitor ZD6474 in combination with radiotherapy and temozolomide in an orthotopic glioma model.
    Journal of neuro-oncology, 2008, Volume: 88, Issue:1

    Topics: Animals; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Brain; B

2008
Effects of the VEGFR inhibitor ZD6474 in combination with radiotherapy and temozolomide in an orthotopic glioma model.
    Journal of neuro-oncology, 2008, Volume: 88, Issue:1

    Topics: Animals; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Brain; B

2008
The added value of concurrently administered temozolomide versus adjuvant temozolomide alone in newly diagnosed glioblastoma.
    Journal of neuro-oncology, 2008, Volume: 88, Issue:1

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Antineoplastic Protocols; Brain Neoplasms; Chemother

2008
The added value of concurrently administered temozolomide versus adjuvant temozolomide alone in newly diagnosed glioblastoma.
    Journal of neuro-oncology, 2008, Volume: 88, Issue:1

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Antineoplastic Protocols; Brain Neoplasms; Chemother

2008
The added value of concurrently administered temozolomide versus adjuvant temozolomide alone in newly diagnosed glioblastoma.
    Journal of neuro-oncology, 2008, Volume: 88, Issue:1

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Antineoplastic Protocols; Brain Neoplasms; Chemother

2008
[Treatment of marignant brain tumor: today and tomorrow].
    No shinkei geka. Neurological surgery, 2008, Volume: 36, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cancer Vaccines; Dacarbazine; Genetic Therapy; H

2008
[Treatment of marignant brain tumor: today and tomorrow].
    No shinkei geka. Neurological surgery, 2008, Volume: 36, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cancer Vaccines; Dacarbazine; Genetic Therapy; H

2008
[Treatment of marignant brain tumor: today and tomorrow].
    No shinkei geka. Neurological surgery, 2008, Volume: 36, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cancer Vaccines; Dacarbazine; Genetic Therapy; H

2008
In vitro and in vivo radiosensitization induced by the DNA methylating agent temozolomide.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2008, Feb-01, Volume: 14, Issue:3

    Topics: Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cell Cycle; Cell Line, Tumor; Dacarba

2008
In vitro and in vivo radiosensitization induced by the DNA methylating agent temozolomide.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2008, Feb-01, Volume: 14, Issue:3

    Topics: Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cell Cycle; Cell Line, Tumor; Dacarba

2008
In vitro and in vivo radiosensitization induced by the DNA methylating agent temozolomide.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2008, Feb-01, Volume: 14, Issue:3

    Topics: Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cell Cycle; Cell Line, Tumor; Dacarba

2008
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma in elderly patients.
    Journal of neuro-oncology, 2008, Volume: 88, Issue:1

    Topics: Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant; Combined Modality

2008
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma in elderly patients.
    Journal of neuro-oncology, 2008, Volume: 88, Issue:1

    Topics: Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant; Combined Modality

2008
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma in elderly patients.
    Journal of neuro-oncology, 2008, Volume: 88, Issue:1

    Topics: Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant; Combined Modality

2008
[Chemotherapy for brain tumors in adult patients].
    Der Nervenarzt, 2008, Volume: 79, Issue:2

    Topics: Adult; Antineoplastic Agents; Brain Neoplasms; Chemotherapy, Adjuvant; Chromosomes, Human, Pair 1; C

2008
[Chemotherapy for brain tumors in adult patients].
    Der Nervenarzt, 2008, Volume: 79, Issue:2

    Topics: Adult; Antineoplastic Agents; Brain Neoplasms; Chemotherapy, Adjuvant; Chromosomes, Human, Pair 1; C

2008
[Chemotherapy for brain tumors in adult patients].
    Der Nervenarzt, 2008, Volume: 79, Issue:2

    Topics: Adult; Antineoplastic Agents; Brain Neoplasms; Chemotherapy, Adjuvant; Chromosomes, Human, Pair 1; C

2008
Astroblastoma with rhabdoid features and favorable long-term outcome: report of a case with a 12-year follow-up.
    Pathology, research and practice, 2008, Volume: 204, Issue:5

    Topics: Antibodies, Antinuclear; Antibodies, Monoclonal; Antineoplastic Agents, Alkylating; Brain Neoplasms;

2008
Astroblastoma with rhabdoid features and favorable long-term outcome: report of a case with a 12-year follow-up.
    Pathology, research and practice, 2008, Volume: 204, Issue:5

    Topics: Antibodies, Antinuclear; Antibodies, Monoclonal; Antineoplastic Agents, Alkylating; Brain Neoplasms;

2008
Astroblastoma with rhabdoid features and favorable long-term outcome: report of a case with a 12-year follow-up.
    Pathology, research and practice, 2008, Volume: 204, Issue:5

    Topics: Antibodies, Antinuclear; Antibodies, Monoclonal; Antineoplastic Agents, Alkylating; Brain Neoplasms;

2008
Treatment of recurrent glioblastoma: can local delivery of mitoxantrone improve survival?
    Journal of neuro-oncology, 2008, Volume: 88, Issue:1

    Topics: Adult; Aged; Aging; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combi

2008
Treatment of recurrent glioblastoma: can local delivery of mitoxantrone improve survival?
    Journal of neuro-oncology, 2008, Volume: 88, Issue:1

    Topics: Adult; Aged; Aging; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combi

2008
Treatment of recurrent glioblastoma: can local delivery of mitoxantrone improve survival?
    Journal of neuro-oncology, 2008, Volume: 88, Issue:1

    Topics: Adult; Aged; Aging; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combi

2008
Evidence of galectin-1 involvement in glioma chemoresistance.
    Toxicology and applied pharmacology, 2008, Jun-01, Volume: 229, Issue:2

    Topics: Animals; Antineoplastic Agents; Apoptosis; Autophagy; Brain Neoplasms; Cell Line, Tumor; Dacarbazine

2008
Evidence of galectin-1 involvement in glioma chemoresistance.
    Toxicology and applied pharmacology, 2008, Jun-01, Volume: 229, Issue:2

    Topics: Animals; Antineoplastic Agents; Apoptosis; Autophagy; Brain Neoplasms; Cell Line, Tumor; Dacarbazine

2008
Evidence of galectin-1 involvement in glioma chemoresistance.
    Toxicology and applied pharmacology, 2008, Jun-01, Volume: 229, Issue:2

    Topics: Animals; Antineoplastic Agents; Apoptosis; Autophagy; Brain Neoplasms; Cell Line, Tumor; Dacarbazine

2008
Complete response after one cycle of temozolomide in an elderly patient with glioblastoma and poor performance status.
    Journal of neuro-oncology, 2008, Volume: 88, Issue:2

    Topics: Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chromosome Deletion; Chromosomes, Human, X

2008
Complete response after one cycle of temozolomide in an elderly patient with glioblastoma and poor performance status.
    Journal of neuro-oncology, 2008, Volume: 88, Issue:2

    Topics: Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chromosome Deletion; Chromosomes, Human, X

2008
Complete response after one cycle of temozolomide in an elderly patient with glioblastoma and poor performance status.
    Journal of neuro-oncology, 2008, Volume: 88, Issue:2

    Topics: Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chromosome Deletion; Chromosomes, Human, X

2008
[Temozolomide: Temodal].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2008, Volume: 35, Issue:3

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Clinical Trials as Topic; Dac

2008
[Temozolomide: Temodal].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2008, Volume: 35, Issue:3

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Clinical Trials as Topic; Dac

2008
[Temozolomide: Temodal].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2008, Volume: 35, Issue:3

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Clinical Trials as Topic; Dac

2008
Glioblastoma in a patient with a hereditary cancer syndrome.
    The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques, 2008, Volume: 35, Issue:1

    Topics: Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cerebral Hemorrhage; Colorectal Neoplasms;

2008
Glioblastoma in a patient with a hereditary cancer syndrome.
    The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques, 2008, Volume: 35, Issue:1

    Topics: Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cerebral Hemorrhage; Colorectal Neoplasms;

2008
Glioblastoma in a patient with a hereditary cancer syndrome.
    The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques, 2008, Volume: 35, Issue:1

    Topics: Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cerebral Hemorrhage; Colorectal Neoplasms;

2008
A retrospective study of the safety of BCNU wafers with concurrent temozolomide and radiotherapy and adjuvant temozolomide for newly diagnosed glioblastoma patients.
    Journal of neuro-oncology, 2008, Volume: 88, Issue:3

    Topics: Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carmustine; Chemotherapy, Adjuvant;

2008
A retrospective study of the safety of BCNU wafers with concurrent temozolomide and radiotherapy and adjuvant temozolomide for newly diagnosed glioblastoma patients.
    Journal of neuro-oncology, 2008, Volume: 88, Issue:3

    Topics: Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carmustine; Chemotherapy, Adjuvant;

2008
A retrospective study of the safety of BCNU wafers with concurrent temozolomide and radiotherapy and adjuvant temozolomide for newly diagnosed glioblastoma patients.
    Journal of neuro-oncology, 2008, Volume: 88, Issue:3

    Topics: Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carmustine; Chemotherapy, Adjuvant;

2008
[The sodium pump could constitute a new target to combat glioblastomas].
    Bulletin du cancer, 2008, Volume: 95, Issue:3

    Topics: Animals; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Phytogenic; Apoptosis; Autophagy;

2008
[The sodium pump could constitute a new target to combat glioblastomas].
    Bulletin du cancer, 2008, Volume: 95, Issue:3

    Topics: Animals; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Phytogenic; Apoptosis; Autophagy;

2008
[The sodium pump could constitute a new target to combat glioblastomas].
    Bulletin du cancer, 2008, Volume: 95, Issue:3

    Topics: Animals; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Phytogenic; Apoptosis; Autophagy;

2008
Comparative evaluation of radiochemotherapy with temozolomide versus standard-of-care postoperative radiation alone in patients with WHO grade III astrocytic tumors.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2008, Volume: 88, Issue:2

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neoplasms; Child; Com

2008
Comparative evaluation of radiochemotherapy with temozolomide versus standard-of-care postoperative radiation alone in patients with WHO grade III astrocytic tumors.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2008, Volume: 88, Issue:2

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neoplasms; Child; Com

2008
Comparative evaluation of radiochemotherapy with temozolomide versus standard-of-care postoperative radiation alone in patients with WHO grade III astrocytic tumors.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2008, Volume: 88, Issue:2

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neoplasms; Child; Com

2008
Low grade astrocytoma presenting with visual loss.
    Journal of neuro-oncology, 2008, Volume: 89, Issue:1

    Topics: Adolescent; Antineoplastic Agents, Alkylating; Astrocytoma; Biomarkers, Tumor; Brain Neoplasms; Daca

2008
Low grade astrocytoma presenting with visual loss.
    Journal of neuro-oncology, 2008, Volume: 89, Issue:1

    Topics: Adolescent; Antineoplastic Agents, Alkylating; Astrocytoma; Biomarkers, Tumor; Brain Neoplasms; Daca

2008
Low grade astrocytoma presenting with visual loss.
    Journal of neuro-oncology, 2008, Volume: 89, Issue:1

    Topics: Adolescent; Antineoplastic Agents, Alkylating; Astrocytoma; Biomarkers, Tumor; Brain Neoplasms; Daca

2008
Cryptococcal meningitis in patients with glioma: a report of two cases.
    Journal of neuro-oncology, 2008, Volume: 89, Issue:1

    Topics: Adult; Aged; Amphotericin B; Anti-Inflammatory Agents; Antifungal Agents; Antineoplastic Agents, Alk

2008
Cryptococcal meningitis in patients with glioma: a report of two cases.
    Journal of neuro-oncology, 2008, Volume: 89, Issue:1

    Topics: Adult; Aged; Amphotericin B; Anti-Inflammatory Agents; Antifungal Agents; Antineoplastic Agents, Alk

2008
Cryptococcal meningitis in patients with glioma: a report of two cases.
    Journal of neuro-oncology, 2008, Volume: 89, Issue:1

    Topics: Adult; Aged; Amphotericin B; Anti-Inflammatory Agents; Antifungal Agents; Antineoplastic Agents, Alk

2008
[Glioblastomas are resistant to apoptosis but less resistant to the autophagic process].
    Bulletin et memoires de l'Academie royale de medecine de Belgique, 2007, Volume: 162, Issue:5-6

    Topics: Algorithms; Antibiotics, Antineoplastic; Antineoplastic Agents, Alkylating; Apoptosis; Autophagy; Br

2007
[Glioblastomas are resistant to apoptosis but less resistant to the autophagic process].
    Bulletin et memoires de l'Academie royale de medecine de Belgique, 2007, Volume: 162, Issue:5-6

    Topics: Algorithms; Antibiotics, Antineoplastic; Antineoplastic Agents, Alkylating; Apoptosis; Autophagy; Br

2007
[Glioblastomas are resistant to apoptosis but less resistant to the autophagic process].
    Bulletin et memoires de l'Academie royale de medecine de Belgique, 2007, Volume: 162, Issue:5-6

    Topics: Algorithms; Antibiotics, Antineoplastic; Antineoplastic Agents, Alkylating; Apoptosis; Autophagy; Br

2007
Multifocal glioblastoma multiforme with synchronous spontaneous hemorrhage: case report.
    Journal of neuro-oncology, 2008, Volume: 89, Issue:1

    Topics: Aged; Antineoplastic Agents, Alkylating; Biomarkers, Tumor; Biopsy; Brain Neoplasms; Cerebral Hemorr

2008
Multifocal glioblastoma multiforme with synchronous spontaneous hemorrhage: case report.
    Journal of neuro-oncology, 2008, Volume: 89, Issue:1

    Topics: Aged; Antineoplastic Agents, Alkylating; Biomarkers, Tumor; Biopsy; Brain Neoplasms; Cerebral Hemorr

2008
Multifocal glioblastoma multiforme with synchronous spontaneous hemorrhage: case report.
    Journal of neuro-oncology, 2008, Volume: 89, Issue:1

    Topics: Aged; Antineoplastic Agents, Alkylating; Biomarkers, Tumor; Biopsy; Brain Neoplasms; Cerebral Hemorr

2008
Knocking down galectin 1 in human hs683 glioblastoma cells impairs both angiogenesis and endoplasmic reticulum stress responses.
    Journal of neuropathology and experimental neurology, 2008, Volume: 67, Issue:5

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Dacarbazine; Down-Reg

2008
Knocking down galectin 1 in human hs683 glioblastoma cells impairs both angiogenesis and endoplasmic reticulum stress responses.
    Journal of neuropathology and experimental neurology, 2008, Volume: 67, Issue:5

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Dacarbazine; Down-Reg

2008
Knocking down galectin 1 in human hs683 glioblastoma cells impairs both angiogenesis and endoplasmic reticulum stress responses.
    Journal of neuropathology and experimental neurology, 2008, Volume: 67, Issue:5

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Dacarbazine; Down-Reg

2008
Modulatory effects of acetazolomide and dexamethasone on temozolomide-mediated apoptosis in human glioblastoma T98G and U87MG cells.
    Cancer investigation, 2008, Volume: 26, Issue:4

    Topics: Acetazolamide; Apoptosis; Aquaporin 1; Brain Edema; Brain Neoplasms; Calpain; Carbonic Anhydrases; C

2008
Modulatory effects of acetazolomide and dexamethasone on temozolomide-mediated apoptosis in human glioblastoma T98G and U87MG cells.
    Cancer investigation, 2008, Volume: 26, Issue:4

    Topics: Acetazolamide; Apoptosis; Aquaporin 1; Brain Edema; Brain Neoplasms; Calpain; Carbonic Anhydrases; C

2008
Modulatory effects of acetazolomide and dexamethasone on temozolomide-mediated apoptosis in human glioblastoma T98G and U87MG cells.
    Cancer investigation, 2008, Volume: 26, Issue:4

    Topics: Acetazolamide; Apoptosis; Aquaporin 1; Brain Edema; Brain Neoplasms; Calpain; Carbonic Anhydrases; C

2008
MGMT promoter methylation status can predict the incidence and outcome of pseudoprogression after concomitant radiochemotherapy in newly diagnosed glioblastoma patients.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2008, May-01, Volume: 26, Issue:13

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Diseases; Brain Neoplasms; Chemotherapy, Adjuv

2008
MGMT promoter methylation status can predict the incidence and outcome of pseudoprogression after concomitant radiochemotherapy in newly diagnosed glioblastoma patients.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2008, May-01, Volume: 26, Issue:13

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Diseases; Brain Neoplasms; Chemotherapy, Adjuv

2008
MGMT promoter methylation status can predict the incidence and outcome of pseudoprogression after concomitant radiochemotherapy in newly diagnosed glioblastoma patients.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2008, May-01, Volume: 26, Issue:13

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Diseases; Brain Neoplasms; Chemotherapy, Adjuv

2008
Malignant gliomas with primitive neuroectodermal tumor-like components: a clinicopathologic and genetic study of 53 cases.
    Brain pathology (Zurich, Switzerland), 2009, Volume: 19, Issue:1

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Comb

2009
Malignant gliomas with primitive neuroectodermal tumor-like components: a clinicopathologic and genetic study of 53 cases.
    Brain pathology (Zurich, Switzerland), 2009, Volume: 19, Issue:1

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Comb

2009
Malignant gliomas with primitive neuroectodermal tumor-like components: a clinicopathologic and genetic study of 53 cases.
    Brain pathology (Zurich, Switzerland), 2009, Volume: 19, Issue:1

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Comb

2009
Adjuvant temozolomide: how long and how much?
    Expert review of anticancer therapy, 2008, Volume: 8, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant; Dacarbazine; Drug Admini

2008
Adjuvant temozolomide: how long and how much?
    Expert review of anticancer therapy, 2008, Volume: 8, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant; Dacarbazine; Drug Admini

2008
Adjuvant temozolomide: how long and how much?
    Expert review of anticancer therapy, 2008, Volume: 8, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant; Dacarbazine; Drug Admini

2008
Enhancement of glioma radiotherapy and chemotherapy response with targeted antibody therapy against death receptor 5.
    International journal of radiation oncology, biology, physics, 2008, Jun-01, Volume: 71, Issue:2

    Topics: Animals; Antibodies, Monoclonal; Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cell

2008
Enhancement of glioma radiotherapy and chemotherapy response with targeted antibody therapy against death receptor 5.
    International journal of radiation oncology, biology, physics, 2008, Jun-01, Volume: 71, Issue:2

    Topics: Animals; Antibodies, Monoclonal; Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cell

2008
Enhancement of glioma radiotherapy and chemotherapy response with targeted antibody therapy against death receptor 5.
    International journal of radiation oncology, biology, physics, 2008, Jun-01, Volume: 71, Issue:2

    Topics: Animals; Antibodies, Monoclonal; Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cell

2008
Preclinical antitumor activity of temozolomide in mice: efficacy against human brain tumor xenografts and synergism with 1,3-bis(2-chloroethyl)-1-nitrosourea.
    Cancer research, 1994, Jul-15, Volume: 54, Issue:14

    Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Car

1994
Preclinical antitumor activity of temozolomide in mice: efficacy against human brain tumor xenografts and synergism with 1,3-bis(2-chloroethyl)-1-nitrosourea.
    Cancer research, 1994, Jul-15, Volume: 54, Issue:14

    Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Car

1994
Preclinical antitumor activity of temozolomide in mice: efficacy against human brain tumor xenografts and synergism with 1,3-bis(2-chloroethyl)-1-nitrosourea.
    Cancer research, 1994, Jul-15, Volume: 54, Issue:14

    Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Car

1994
From triazines and triazenes to temozolomide.
    European journal of cancer (Oxford, England : 1990), 1993, Volume: 29A, Issue:7

    Topics: Animals; Antineoplastic Agents; Astrocytoma; Brain Neoplasms; Chemistry, Pharmaceutical; Dacarbazine

1993
From triazines and triazenes to temozolomide.
    European journal of cancer (Oxford, England : 1990), 1993, Volume: 29A, Issue:7

    Topics: Animals; Antineoplastic Agents; Astrocytoma; Brain Neoplasms; Chemistry, Pharmaceutical; Dacarbazine

1993
From triazines and triazenes to temozolomide.
    European journal of cancer (Oxford, England : 1990), 1993, Volume: 29A, Issue:7

    Topics: Animals; Antineoplastic Agents; Astrocytoma; Brain Neoplasms; Chemistry, Pharmaceutical; Dacarbazine

1993
Uptake of temozolomide in a rat glioma model in the presence and absence of the angiogenesis inhibitor TNP-470.
    Cancer research, 1996, May-01, Volume: 56, Issue:9

    Topics: Animals; Antibiotics, Antineoplastic; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cyclohexan

1996
Uptake of temozolomide in a rat glioma model in the presence and absence of the angiogenesis inhibitor TNP-470.
    Cancer research, 1996, May-01, Volume: 56, Issue:9

    Topics: Animals; Antibiotics, Antineoplastic; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cyclohexan

1996
Uptake of temozolomide in a rat glioma model in the presence and absence of the angiogenesis inhibitor TNP-470.
    Cancer research, 1996, May-01, Volume: 56, Issue:9

    Topics: Animals; Antibiotics, Antineoplastic; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cyclohexan

1996
In vitro evaluation of temozolomide combined with X-irradiation.
    Anti-cancer drugs, 1997, Volume: 8, Issue:1

    Topics: Adenocarcinoma; Antineoplastic Agents, Alkylating; Brain Neoplasms; Colonic Neoplasms; Combined Moda

1997
In vitro evaluation of temozolomide combined with X-irradiation.
    Anti-cancer drugs, 1997, Volume: 8, Issue:1

    Topics: Adenocarcinoma; Antineoplastic Agents, Alkylating; Brain Neoplasms; Colonic Neoplasms; Combined Moda

1997
In vitro evaluation of temozolomide combined with X-irradiation.
    Anti-cancer drugs, 1997, Volume: 8, Issue:1

    Topics: Adenocarcinoma; Antineoplastic Agents, Alkylating; Brain Neoplasms; Colonic Neoplasms; Combined Moda

1997
Activity of temozolomide against human tumor colony-forming units.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 1997, Volume: 3, Issue:10

    Topics: Adrenal Gland Neoplasms; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Brain Neoplasms;

1997
Activity of temozolomide against human tumor colony-forming units.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 1997, Volume: 3, Issue:10

    Topics: Adrenal Gland Neoplasms; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Brain Neoplasms;

1997
Activity of temozolomide against human tumor colony-forming units.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 1997, Volume: 3, Issue:10

    Topics: Adrenal Gland Neoplasms; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Brain Neoplasms;

1997
Role of O6-methylguanine-DNA methyltransferase in resistance of human brain tumor cell lines to the clinically relevant methylating agents temozolomide and streptozotocin.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 1996, Volume: 2, Issue:4

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Drug Resistance, Neoplasm; Guanine;

1996
Role of O6-methylguanine-DNA methyltransferase in resistance of human brain tumor cell lines to the clinically relevant methylating agents temozolomide and streptozotocin.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 1996, Volume: 2, Issue:4

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Drug Resistance, Neoplasm; Guanine;

1996
Role of O6-methylguanine-DNA methyltransferase in resistance of human brain tumor cell lines to the clinically relevant methylating agents temozolomide and streptozotocin.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 1996, Volume: 2, Issue:4

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Drug Resistance, Neoplasm; Guanine;

1996
DNA mismatch repair and O6-alkylguanine-DNA alkyltransferase analysis and response to Temodal in newly diagnosed malignant glioma.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1998, Volume: 16, Issue:12

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; DNA Repair; DNA, Neopl

1998
DNA mismatch repair and O6-alkylguanine-DNA alkyltransferase analysis and response to Temodal in newly diagnosed malignant glioma.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1998, Volume: 16, Issue:12

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; DNA Repair; DNA, Neopl

1998
DNA mismatch repair and O6-alkylguanine-DNA alkyltransferase analysis and response to Temodal in newly diagnosed malignant glioma.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1998, Volume: 16, Issue:12

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; DNA Repair; DNA, Neopl

1998
Sensitivity of short-term cultures derived from human malignant glioma to the anti-cancer drug temozolomide.
    Anti-cancer drugs, 1999, Volume: 10, Issue:2

    Topics: Adult; Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neoplasms; Dacarbazine; Dose-Response R

1999
Sensitivity of short-term cultures derived from human malignant glioma to the anti-cancer drug temozolomide.
    Anti-cancer drugs, 1999, Volume: 10, Issue:2

    Topics: Adult; Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neoplasms; Dacarbazine; Dose-Response R

1999
Sensitivity of short-term cultures derived from human malignant glioma to the anti-cancer drug temozolomide.
    Anti-cancer drugs, 1999, Volume: 10, Issue:2

    Topics: Adult; Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neoplasms; Dacarbazine; Dose-Response R

1999
Oral temozolomide approved for refractory brain tumor.
    American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 1999, Oct-01, Volume: 56, Issue:19

    Topics: Administration, Oral; Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neoplasms; Dacarbazine;

1999
Oral temozolomide approved for refractory brain tumor.
    American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 1999, Oct-01, Volume: 56, Issue:19

    Topics: Administration, Oral; Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neoplasms; Dacarbazine;

1999
Oral temozolomide approved for refractory brain tumor.
    American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 1999, Oct-01, Volume: 56, Issue:19

    Topics: Administration, Oral; Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neoplasms; Dacarbazine;

1999
Biochemical correlates of temozolomide sensitivity in pediatric solid tumor xenograft models.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2000, Volume: 6, Issue:3

    Topics: Adaptor Proteins, Signal Transducing; Animals; Antineoplastic Agents, Alkylating; Base Pair Mismatch

2000
Biochemical correlates of temozolomide sensitivity in pediatric solid tumor xenograft models.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2000, Volume: 6, Issue:3

    Topics: Adaptor Proteins, Signal Transducing; Animals; Antineoplastic Agents, Alkylating; Base Pair Mismatch

2000
Biochemical correlates of temozolomide sensitivity in pediatric solid tumor xenograft models.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2000, Volume: 6, Issue:3

    Topics: Adaptor Proteins, Signal Transducing; Animals; Antineoplastic Agents, Alkylating; Base Pair Mismatch

2000
Salvage therapy with temozolomide in an immunocompetent patient with primary brain lymphoma.
    Journal of the National Cancer Institute, 2000, Apr-05, Volume: 92, Issue:7

    Topics: Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Humans; Immunocompetence; Lym

2000
Salvage therapy with temozolomide in an immunocompetent patient with primary brain lymphoma.
    Journal of the National Cancer Institute, 2000, Apr-05, Volume: 92, Issue:7

    Topics: Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Humans; Immunocompetence; Lym

2000
Salvage therapy with temozolomide in an immunocompetent patient with primary brain lymphoma.
    Journal of the National Cancer Institute, 2000, Apr-05, Volume: 92, Issue:7

    Topics: Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Humans; Immunocompetence; Lym

2000
Temozolomide (Temodal) for treatment of primary brain tumours.
    Intensive & critical care nursing, 2000, Volume: 16, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Drug Monitoring; Glioblastoma; Huma

2000
Temozolomide (Temodal) for treatment of primary brain tumours.
    Intensive & critical care nursing, 2000, Volume: 16, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Drug Monitoring; Glioblastoma; Huma

2000
Temozolomide (Temodal) for treatment of primary brain tumours.
    Intensive & critical care nursing, 2000, Volume: 16, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Drug Monitoring; Glioblastoma; Huma

2000
Temozolomide for malignant brain tumours.
    Lancet (London, England), 2000, Apr-01, Volume: 355, Issue:9210

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Clinical Trials as Topic; Dacarbazine; Glioblast

2000
Temozolomide for malignant brain tumours.
    Lancet (London, England), 2000, Apr-01, Volume: 355, Issue:9210

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Clinical Trials as Topic; Dacarbazine; Glioblast

2000
Temozolomide for malignant brain tumours.
    Lancet (London, England), 2000, Apr-01, Volume: 355, Issue:9210

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Clinical Trials as Topic; Dacarbazine; Glioblast

2000
Survival of human glioma cells treated with various combination of temozolomide and X-rays.
    International journal of radiation oncology, biology, physics, 2000, Jun-01, Volume: 47, Issue:3

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Survival; Combined Modality Therapy; Dacarb

2000
Survival of human glioma cells treated with various combination of temozolomide and X-rays.
    International journal of radiation oncology, biology, physics, 2000, Jun-01, Volume: 47, Issue:3

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Survival; Combined Modality Therapy; Dacarb

2000
Survival of human glioma cells treated with various combination of temozolomide and X-rays.
    International journal of radiation oncology, biology, physics, 2000, Jun-01, Volume: 47, Issue:3

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Survival; Combined Modality Therapy; Dacarb

2000
Temozolomide for refractory anaplastic astrocytoma.
    The Medical letter on drugs and therapeutics, 1999, Dec-17, Volume: 41, Issue:1068

    Topics: Administration, Oral; Adult; Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neoplasms; Clinic

1999
Temozolomide for refractory anaplastic astrocytoma.
    The Medical letter on drugs and therapeutics, 1999, Dec-17, Volume: 41, Issue:1068

    Topics: Administration, Oral; Adult; Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neoplasms; Clinic

1999
Temozolomide for refractory anaplastic astrocytoma.
    The Medical letter on drugs and therapeutics, 1999, Dec-17, Volume: 41, Issue:1068

    Topics: Administration, Oral; Adult; Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neoplasms; Clinic

1999
Antitumor activity of temozolomide combined with irinotecan is partly independent of O6-methylguanine-DNA methyltransferase and mismatch repair phenotypes in xenograft models.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2000, Volume: 6, Issue:10

    Topics: Administration, Oral; Alkylating Agents; Animals; Antineoplastic Agents, Alkylating; Antineoplastic

2000
Antitumor activity of temozolomide combined with irinotecan is partly independent of O6-methylguanine-DNA methyltransferase and mismatch repair phenotypes in xenograft models.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2000, Volume: 6, Issue:10

    Topics: Administration, Oral; Alkylating Agents; Animals; Antineoplastic Agents, Alkylating; Antineoplastic

2000
Antitumor activity of temozolomide combined with irinotecan is partly independent of O6-methylguanine-DNA methyltransferase and mismatch repair phenotypes in xenograft models.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2000, Volume: 6, Issue:10

    Topics: Administration, Oral; Alkylating Agents; Animals; Antineoplastic Agents, Alkylating; Antineoplastic

2000
Antitumor activity of temozolomide combined with irinotecan is partly independent of O6-methylguanine-DNA methyltransferase and mismatch repair phenotypes in xenograft models.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2000, Volume: 6, Issue:10

    Topics: Administration, Oral; Alkylating Agents; Animals; Antineoplastic Agents, Alkylating; Antineoplastic

2000
Antitumor activity of temozolomide combined with irinotecan is partly independent of O6-methylguanine-DNA methyltransferase and mismatch repair phenotypes in xenograft models.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2000, Volume: 6, Issue:10

    Topics: Administration, Oral; Alkylating Agents; Animals; Antineoplastic Agents, Alkylating; Antineoplastic

2000
Antitumor activity of temozolomide combined with irinotecan is partly independent of O6-methylguanine-DNA methyltransferase and mismatch repair phenotypes in xenograft models.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2000, Volume: 6, Issue:10

    Topics: Administration, Oral; Alkylating Agents; Animals; Antineoplastic Agents, Alkylating; Antineoplastic

2000
Antitumor activity of temozolomide combined with irinotecan is partly independent of O6-methylguanine-DNA methyltransferase and mismatch repair phenotypes in xenograft models.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2000, Volume: 6, Issue:10

    Topics: Administration, Oral; Alkylating Agents; Animals; Antineoplastic Agents, Alkylating; Antineoplastic

2000
Antitumor activity of temozolomide combined with irinotecan is partly independent of O6-methylguanine-DNA methyltransferase and mismatch repair phenotypes in xenograft models.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2000, Volume: 6, Issue:10

    Topics: Administration, Oral; Alkylating Agents; Animals; Antineoplastic Agents, Alkylating; Antineoplastic

2000
Antitumor activity of temozolomide combined with irinotecan is partly independent of O6-methylguanine-DNA methyltransferase and mismatch repair phenotypes in xenograft models.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2000, Volume: 6, Issue:10

    Topics: Administration, Oral; Alkylating Agents; Animals; Antineoplastic Agents, Alkylating; Antineoplastic

2000
Antitumor activity of temozolomide combined with irinotecan is partly independent of O6-methylguanine-DNA methyltransferase and mismatch repair phenotypes in xenograft models.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2000, Volume: 6, Issue:10

    Topics: Administration, Oral; Alkylating Agents; Animals; Antineoplastic Agents, Alkylating; Antineoplastic

2000
Antitumor activity of temozolomide combined with irinotecan is partly independent of O6-methylguanine-DNA methyltransferase and mismatch repair phenotypes in xenograft models.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2000, Volume: 6, Issue:10

    Topics: Administration, Oral; Alkylating Agents; Animals; Antineoplastic Agents, Alkylating; Antineoplastic

2000
Antitumor activity of temozolomide combined with irinotecan is partly independent of O6-methylguanine-DNA methyltransferase and mismatch repair phenotypes in xenograft models.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2000, Volume: 6, Issue:10

    Topics: Administration, Oral; Alkylating Agents; Animals; Antineoplastic Agents, Alkylating; Antineoplastic

2000
Antitumor activity of temozolomide combined with irinotecan is partly independent of O6-methylguanine-DNA methyltransferase and mismatch repair phenotypes in xenograft models.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2000, Volume: 6, Issue:10

    Topics: Administration, Oral; Alkylating Agents; Animals; Antineoplastic Agents, Alkylating; Antineoplastic

2000
Antitumor activity of temozolomide combined with irinotecan is partly independent of O6-methylguanine-DNA methyltransferase and mismatch repair phenotypes in xenograft models.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2000, Volume: 6, Issue:10

    Topics: Administration, Oral; Alkylating Agents; Animals; Antineoplastic Agents, Alkylating; Antineoplastic

2000
Antitumor activity of temozolomide combined with irinotecan is partly independent of O6-methylguanine-DNA methyltransferase and mismatch repair phenotypes in xenograft models.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2000, Volume: 6, Issue:10

    Topics: Administration, Oral; Alkylating Agents; Animals; Antineoplastic Agents, Alkylating; Antineoplastic

2000
Antitumor activity of temozolomide combined with irinotecan is partly independent of O6-methylguanine-DNA methyltransferase and mismatch repair phenotypes in xenograft models.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2000, Volume: 6, Issue:10

    Topics: Administration, Oral; Alkylating Agents; Animals; Antineoplastic Agents, Alkylating; Antineoplastic

2000
Antitumor activity of temozolomide combined with irinotecan is partly independent of O6-methylguanine-DNA methyltransferase and mismatch repair phenotypes in xenograft models.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2000, Volume: 6, Issue:10

    Topics: Administration, Oral; Alkylating Agents; Animals; Antineoplastic Agents, Alkylating; Antineoplastic

2000
Antitumor activity of temozolomide combined with irinotecan is partly independent of O6-methylguanine-DNA methyltransferase and mismatch repair phenotypes in xenograft models.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2000, Volume: 6, Issue:10

    Topics: Administration, Oral; Alkylating Agents; Animals; Antineoplastic Agents, Alkylating; Antineoplastic

2000
Antitumor activity of temozolomide combined with irinotecan is partly independent of O6-methylguanine-DNA methyltransferase and mismatch repair phenotypes in xenograft models.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2000, Volume: 6, Issue:10

    Topics: Administration, Oral; Alkylating Agents; Animals; Antineoplastic Agents, Alkylating; Antineoplastic

2000
Antitumor activity of temozolomide combined with irinotecan is partly independent of O6-methylguanine-DNA methyltransferase and mismatch repair phenotypes in xenograft models.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2000, Volume: 6, Issue:10

    Topics: Administration, Oral; Alkylating Agents; Animals; Antineoplastic Agents, Alkylating; Antineoplastic

2000
Antitumor activity of temozolomide combined with irinotecan is partly independent of O6-methylguanine-DNA methyltransferase and mismatch repair phenotypes in xenograft models.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2000, Volume: 6, Issue:10

    Topics: Administration, Oral; Alkylating Agents; Animals; Antineoplastic Agents, Alkylating; Antineoplastic

2000
Antitumor activity of temozolomide combined with irinotecan is partly independent of O6-methylguanine-DNA methyltransferase and mismatch repair phenotypes in xenograft models.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2000, Volume: 6, Issue:10

    Topics: Administration, Oral; Alkylating Agents; Animals; Antineoplastic Agents, Alkylating; Antineoplastic

2000
Antitumor activity of temozolomide combined with irinotecan is partly independent of O6-methylguanine-DNA methyltransferase and mismatch repair phenotypes in xenograft models.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2000, Volume: 6, Issue:10

    Topics: Administration, Oral; Alkylating Agents; Animals; Antineoplastic Agents, Alkylating; Antineoplastic

2000
Antitumor activity of temozolomide combined with irinotecan is partly independent of O6-methylguanine-DNA methyltransferase and mismatch repair phenotypes in xenograft models.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2000, Volume: 6, Issue:10

    Topics: Administration, Oral; Alkylating Agents; Animals; Antineoplastic Agents, Alkylating; Antineoplastic

2000
Antitumor activity of temozolomide combined with irinotecan is partly independent of O6-methylguanine-DNA methyltransferase and mismatch repair phenotypes in xenograft models.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2000, Volume: 6, Issue:10

    Topics: Administration, Oral; Alkylating Agents; Animals; Antineoplastic Agents, Alkylating; Antineoplastic

2000
Antitumor activity of temozolomide combined with irinotecan is partly independent of O6-methylguanine-DNA methyltransferase and mismatch repair phenotypes in xenograft models.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2000, Volume: 6, Issue:10

    Topics: Administration, Oral; Alkylating Agents; Animals; Antineoplastic Agents, Alkylating; Antineoplastic

2000
Antitumor activity of temozolomide combined with irinotecan is partly independent of O6-methylguanine-DNA methyltransferase and mismatch repair phenotypes in xenograft models.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2000, Volume: 6, Issue:10

    Topics: Administration, Oral; Alkylating Agents; Animals; Antineoplastic Agents, Alkylating; Antineoplastic

2000
Temozolomide delivered by intracerebral microinfusion is safe and efficacious against malignant gliomas in rats.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2000, Volume: 6, Issue:10

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain; Brain Neoplasms; Catheterization; Catheters, Indw

2000
Temozolomide delivered by intracerebral microinfusion is safe and efficacious against malignant gliomas in rats.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2000, Volume: 6, Issue:10

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain; Brain Neoplasms; Catheterization; Catheters, Indw

2000
Temozolomide delivered by intracerebral microinfusion is safe and efficacious against malignant gliomas in rats.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2000, Volume: 6, Issue:10

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain; Brain Neoplasms; Catheterization; Catheters, Indw

2000
Effects of temozolomide in malignant brain tumours.
    Lancet (London, England), 2000, Jul-22, Volume: 356, Issue:9226

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Clinical Trials, Phase II as Topic; Clinical Tri

2000
Effects of temozolomide in malignant brain tumours.
    Lancet (London, England), 2000, Jul-22, Volume: 356, Issue:9226

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Clinical Trials, Phase II as Topic; Clinical Tri

2000
Effects of temozolomide in malignant brain tumours.
    Lancet (London, England), 2000, Jul-22, Volume: 356, Issue:9226

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Clinical Trials, Phase II as Topic; Clinical Tri

2000
Synergy between methionine stress and chemotherapy in the treatment of brain tumor xenografts in athymic mice.
    Cancer research, 2001, May-15, Volume: 61, Issue:10

    Topics: Animals; Antimetabolites, Antineoplastic; Antineoplastic Agents, Alkylating; Antineoplastic Combined

2001
Synergy between methionine stress and chemotherapy in the treatment of brain tumor xenografts in athymic mice.
    Cancer research, 2001, May-15, Volume: 61, Issue:10

    Topics: Animals; Antimetabolites, Antineoplastic; Antineoplastic Agents, Alkylating; Antineoplastic Combined

2001
Synergy between methionine stress and chemotherapy in the treatment of brain tumor xenografts in athymic mice.
    Cancer research, 2001, May-15, Volume: 61, Issue:10

    Topics: Animals; Antimetabolites, Antineoplastic; Antineoplastic Agents, Alkylating; Antineoplastic Combined

2001
An Australian experience with temozolomide for the treatment of recurrent high grade gliomas.
    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2001, Volume: 8, Issue:4

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Australia; Brain Neoplasms; Dacarbazine; Disease-Fre

2001
An Australian experience with temozolomide for the treatment of recurrent high grade gliomas.
    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2001, Volume: 8, Issue:4

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Australia; Brain Neoplasms; Dacarbazine; Disease-Fre

2001
An Australian experience with temozolomide for the treatment of recurrent high grade gliomas.
    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2001, Volume: 8, Issue:4

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Australia; Brain Neoplasms; Dacarbazine; Disease-Fre

2001
Temozolomide chemotherapy in recurrent oligodendroglioma.
    Neurology, 2001, Jul-24, Volume: 57, Issue:2

    Topics: Adult; Antineoplastic Agents; Brain Neoplasms; Dacarbazine; Humans; Middle Aged; Neoplasm Recurrence

2001
Temozolomide chemotherapy in recurrent oligodendroglioma.
    Neurology, 2001, Jul-24, Volume: 57, Issue:2

    Topics: Adult; Antineoplastic Agents; Brain Neoplasms; Dacarbazine; Humans; Middle Aged; Neoplasm Recurrence

2001
Temozolomide chemotherapy in recurrent oligodendroglioma.
    Neurology, 2001, Jul-24, Volume: 57, Issue:2

    Topics: Adult; Antineoplastic Agents; Brain Neoplasms; Dacarbazine; Humans; Middle Aged; Neoplasm Recurrence

2001
Treatment of brain metastases of malignant melanoma with temozolomide.
    The New England journal of medicine, 2001, Aug-23, Volume: 345, Issue:8

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Humans; Lung Neoplasms; Magnetic Re

2001
Treatment of brain metastases of malignant melanoma with temozolomide.
    The New England journal of medicine, 2001, Aug-23, Volume: 345, Issue:8

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Humans; Lung Neoplasms; Magnetic Re

2001
Treatment of brain metastases of malignant melanoma with temozolomide.
    The New England journal of medicine, 2001, Aug-23, Volume: 345, Issue:8

    Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Humans; Lung Neoplasms; Magnetic Re

2001
Temozolomide enhances herpes simplex virus thymidine kinase/ganciclovir therapy of malignant glioma.
    Cancer gene therapy, 2001, Volume: 8, Issue:9

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Division; Dacarbazine; Drug Intera

2001
Temozolomide enhances herpes simplex virus thymidine kinase/ganciclovir therapy of malignant glioma.
    Cancer gene therapy, 2001, Volume: 8, Issue:9

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Division; Dacarbazine; Drug Intera

2001
Temozolomide enhances herpes simplex virus thymidine kinase/ganciclovir therapy of malignant glioma.
    Cancer gene therapy, 2001, Volume: 8, Issue:9

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Division; Dacarbazine; Drug Intera

2001
Possible efficacy of temozolomide in a patient with gliomatosis cerebri.
    Neurology, 2001, Nov-27, Volume: 57, Issue:10

    Topics: Adult; Antineoplastic Agents, Alkylating; Brain; Brain Neoplasms; Dacarbazine; Humans; Magnetic Reso

2001
Possible efficacy of temozolomide in a patient with gliomatosis cerebri.
    Neurology, 2001, Nov-27, Volume: 57, Issue:10

    Topics: Adult; Antineoplastic Agents, Alkylating; Brain; Brain Neoplasms; Dacarbazine; Humans; Magnetic Reso

2001
Possible efficacy of temozolomide in a patient with gliomatosis cerebri.
    Neurology, 2001, Nov-27, Volume: 57, Issue:10

    Topics: Adult; Antineoplastic Agents, Alkylating; Brain; Brain Neoplasms; Dacarbazine; Humans; Magnetic Reso

2001
Brain metastases from fallopian tube carcinoma responsive to intra-arterial carboplatin and intravenous etoposide: a case report.
    Journal of neuro-oncology, 2001, Volume: 55, Issue:3

    Topics: Adenocarcinoma, Papillary; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy P

2001
Brain metastases from fallopian tube carcinoma responsive to intra-arterial carboplatin and intravenous etoposide: a case report.
    Journal of neuro-oncology, 2001, Volume: 55, Issue:3

    Topics: Adenocarcinoma, Papillary; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy P

2001
Brain metastases from fallopian tube carcinoma responsive to intra-arterial carboplatin and intravenous etoposide: a case report.
    Journal of neuro-oncology, 2001, Volume: 55, Issue:3

    Topics: Adenocarcinoma, Papillary; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy P

2001
NICE verdict on Temozolomide: where next?
    British journal of cancer, 2002, Feb-12, Volume: 86, Issue:4

    Topics: Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neoplasms; Dacarbazine; Disease-Free Survival;

2002
NICE verdict on Temozolomide: where next?
    British journal of cancer, 2002, Feb-12, Volume: 86, Issue:4

    Topics: Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neoplasms; Dacarbazine; Disease-Free Survival;

2002
NICE verdict on Temozolomide: where next?
    British journal of cancer, 2002, Feb-12, Volume: 86, Issue:4

    Topics: Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neoplasms; Dacarbazine; Disease-Free Survival;

2002
Treatment of metastatic melanoma in the brain with temozolomide and thalidomide.
    The Lancet. Oncology, 2001, Volume: 2, Issue:10

    Topics: Adult; Angiogenesis Inhibitors; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Dru

2001
Treatment of metastatic melanoma in the brain with temozolomide and thalidomide.
    The Lancet. Oncology, 2001, Volume: 2, Issue:10

    Topics: Adult; Angiogenesis Inhibitors; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Dru

2001
Treatment of metastatic melanoma in the brain with temozolomide and thalidomide.
    The Lancet. Oncology, 2001, Volume: 2, Issue:10

    Topics: Adult; Angiogenesis Inhibitors; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Dru

2001
Temozolomide-induced flare in high-grade gliomas: a new clinical entity.
    Internal medicine journal, 2002, Volume: 32, Issue:7

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neoplasms; Dacarbazine; Female; G

2002
Temozolomide-induced flare in high-grade gliomas: a new clinical entity.
    Internal medicine journal, 2002, Volume: 32, Issue:7

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neoplasms; Dacarbazine; Female; G

2002
Temozolomide-induced flare in high-grade gliomas: a new clinical entity.
    Internal medicine journal, 2002, Volume: 32, Issue:7

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neoplasms; Dacarbazine; Female; G

2002